Colorectal Cancer Atlas

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transcription factor 7-like 2 (T-cell specific, HMG-box)

This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.[provided by RefSeq, Oct 2010]
Gene official symbol
TCF7L2

Entrez gene ID
6934

Gene aliases
TCF4

Chromosome
10

Map location
10q25.3

Gene type
protein-coding

Gene Ontology (GO) terms enrichment




Database references
602228
11641
ENSG00000148737
OTTHUMG00000019070
VP_6934
ENSG00000148737-TCF7L2


Statistics for TCF7L2

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PTMs
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Sequence variants
Cell lines/tissues
Pathways involved in
Protein-Protein Interactions



Sequence variants for TCF7L2



List of cell lines/tissues that have TCF7L2 sequence variants




List of pathways where TCF7L2 is involved


Pathway name Pathway source

Protein-Protein Interaction Network for TCF7L2



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Number of sequence variations per gene

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Protein identification for TCF7L2


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Identification method Quantitative data available

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Isoform peptide details


Qualitative proteomic data





Post-translational modifications (PTMs) in TCF7L2


Domains for TCF7L2

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