Colorectal Cancer Atlas

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phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. [provided by RefSeq, Jul 2008]
Gene official symbol
PIK3CA

Entrez gene ID
5290

Gene aliases
CLOVE, CWS5, MCAP, MCM, MCMTC, p110-alpha

Chromosome
3

Map location
3q26.3

Gene type
protein-coding

Gene Ontology (GO) terms enrichment




Database references
171834
8975
ENSG00000121879
OTTHUMG00000157311
VP_5290
ENSG00000121879-PIK3CA


Statistics for PIK3CA

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PTMs
Protein entries
Sequence variants
Cell lines/tissues
Pathways involved in
Protein-Protein Interactions



Sequence variants for PIK3CA



List of cell lines/tissues that have PIK3CA sequence variants




List of pathways where PIK3CA is involved


Pathway name Pathway source

Protein-Protein Interaction Network for PIK3CA



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Number of sequence variations per gene

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Protein identification for PIK3CA


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Identification method Quantitative data available

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Isoform peptide details


Qualitative proteomic data





Post-translational modifications (PTMs) in PIK3CA


Domains for PIK3CA

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