Kirsten rat sarcoma viral oncogene homolog
This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008]
Gene aliases
C-K-RAS,
CFC2,
K-RAS2A,
K-RAS2B,
K-RAS4A,
K-RAS4B,
KI-RAS,
KRAS1,
KRAS2,
NS,
RASK2
Chromosome
12
Map location
12p12.1
Gene type
protein-coding
Gene Ontology (GO) terms enrichment
Database references
Statistics for KRAS
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| PTMs | |
| Protein entries | |
| Sequence variants | |
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| Protein-Protein Interactions |
Sequence variants for KRAS
List of cell lines/tissues that have KRAS sequence variants
List of pathways where KRAS is involved
| Pathway name | Pathway source |
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Protein-Protein Interaction Network for KRAS
Network key
Number of sequence variations per gene
Protein identification for KRAS
Browse by protein identification methods
| Identification method | Quantitative data available |
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