cadherin 3, type 1, P-cadherin (placental)
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy. [provided by RefSeq, Jul 2008]
Gene aliases
CDHP,
PCAD
Chromosome
16
Map location
16q22.1
Gene type
protein-coding
Gene Ontology (GO) terms enrichment
Database references
Statistics for CDH3
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| Protein entries | |
| Sequence variants | |
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Sequence variants for CDH3
List of cell lines/tissues that have CDH3 sequence variants
List of pathways where CDH3 is involved
| Pathway name | Pathway source |
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Protein-Protein Interaction Network for CDH3
Network key
Number of sequence variations per gene
Protein identification for CDH3
Browse by protein identification methods
| Identification method | Quantitative data available |
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