aggrecan
This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene. [provided by RefSeq, Jul 2008]
Gene aliases
AGC1,
AGCAN,
CSPG1,
CSPGCP,
SEDK
Chromosome
15
Map location
15q26.1
Gene type
protein-coding
Gene Ontology (GO) terms enrichment
Database references
Statistics for ACAN
| Domains | |
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| PTMs | |
| Protein entries | |
| Sequence variants | |
| Cell lines/tissues | |
| Pathways involved in | |
| Protein-Protein Interactions |
Sequence variants for ACAN
List of cell lines/tissues that have ACAN sequence variants
List of pathways where ACAN is involved
| Pathway name | Pathway source |
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Protein-Protein Interaction Network for ACAN
Network key
Number of sequence variations per gene
Protein identification for ACAN
Browse by protein identification methods
| Identification method | Quantitative data available |
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