official_symbol	entrez_gene_id	description	go_terms	go_types	pubmed_id
CARD11	84433	caspase recruitment domain family, member 11	positive regulation of cytokine production	Biological process	12154360
PAX8	7849	paired box 8	branching involved in ureteric bud morphogenesis	Biological process	1337742
CSNK2A1	1457	casein kinase 2, alpha 1 polypeptide	PcG protein complex	Cellular component	21282530
PPARG	5468	peroxisome proliferator-activated receptor gamma	response to starvation	Biological process	-
TAF1D	79101	TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa	regulation of gene expression, epigenetic	Biological process	-
PURA	5813	purine-rich element binding protein A	dendrite	Cellular component	-
DGKG	1608	diacylglycerol kinase, gamma 90kDa	plasma membrane	Cellular component	-
VWA7	80737	von Willebrand factor A domain containing 7	extracellular region	Cellular component	-
DTD1	92675	D-tyrosyl-tRNA deacylase 1	DNA binding	Molecular function	-
TGFA	7039	transforming growth factor, alpha	angiogenesis	Biological process	-
P2RX3	5024	purinergic receptor P2X, ligand gated ion channel, 3	integral component of nuclear inner membrane	Cellular component	-
RYR3	6263	ryanodine receptor 3	transmembrane transport	Biological process	-
CTNS	1497	cystinosin, lysosomal cystine transporter	long-term memory	Biological process	-
LY6K	54742	lymphocyte antigen 6 complex, locus K	anchored component of membrane	Cellular component	-
TRIM38	10475	tripartite motif containing 38	positive regulation of NF-kappaB transcription factor activity	Biological process	23077300
RHOBTB3	22836	Rho-related BTB domain containing 3	GTP binding	Molecular function	-
ABCF2	10061	ATP-binding cassette, sub-family F (GCN20), member 2	transporter activity	Molecular function	9878413
ALOX12B	242	arachidonate 12-lipoxygenase, 12R type	oxidation-reduction process	Biological process	15629692
RELA	5970	v-rel avian reticuloendotheliosis viral oncogene homolog A	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	17350185
TSPO	706	translocator protein (18kDa)	protein binding	Molecular function	25416956
FUT10	84750	fucosyltransferase 10 (alpha (1,3) fucosyltransferase)	fucosylation	Biological process	11698403
APC	324	adenomatous polyposis coli	negative regulation of microtubule depolymerization	Biological process	17192415
ZNF395	55893	zinc finger protein 395	DNA binding	Molecular function	14625278
FXN	2395	frataxin	response to iron ion	Biological process	18424449
TREH	11181	trehalase (brush-border membrane glycoprotein)	anchored component of plasma membrane	Cellular component	8773341
DRD1	1812	dopamine receptor D1	positive regulation of potassium ion transport	Biological process	-
KCNT2	343450	potassium channel, sodium activated subfamily T, member 2	ATP binding	Molecular function	-
TP53BP2	7159	tumor protein p53 binding protein 2	response to ionizing radiation	Biological process	-
ZNF623	9831	zinc finger protein 623	DNA binding	Molecular function	-
CCL23	6368	chemokine (C-C motif) ligand 23	inflammatory response	Biological process	-
PPP1R1C	151242	protein phosphatase 1, regulatory (inhibitor) subunit 1C	negative regulation of protein kinase activity	Biological process	-
MYH15	22989	myosin, heavy chain 15	actin binding	Molecular function	-
PSMC2	5701	proteasome (prosome, macropain) 26S subunit, ATPase, 2	membrane	Cellular component	16210410
VDAC1	7416	voltage-dependent anion channel 1	pore complex	Cellular component	9843949
MAPK9	5601	mitogen-activated protein kinase 9	JNK cascade	Biological process	-
OR52N5	390075	olfactory receptor, family 52, subfamily N, member 5	G-protein coupled receptor signaling pathway	Biological process	-
RFC1	5981	replication factor C (activator 1) 1, 145kDa	ATP binding	Molecular function	-
PLA2G2A	5320	phospholipase A2, group IIA (platelets, synovial fluid)	mitochondrion	Cellular component	-
ZNF766	90321	zinc finger protein 766	transcription, DNA-templated	Biological process	-
NDUFA9	4704	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa	mitochondrial electron transport, NADH to ubiquinone	Biological process	9878551
RCAN1	1827	regulator of calcineurin 1	central nervous system development	Biological process	8595418
FGD2	221472	FYVE, RhoGEF and PH domain containing 2	early endosome membrane	Cellular component	-
HSD3B7	80270	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	integral component of membrane	Cellular component	-
OASL	8638	2'-5'-oligoadenylate synthetase-like	interferon-gamma-mediated signaling pathway	Biological process	-
HERC2	8924	HECT and RLD domain containing E3 ubiquitin protein ligase 2	cellular protein metabolic process	Biological process	-
PSMC2	5701	proteasome (prosome, macropain) 26S subunit, ATPase, 2	innate immune response	Biological process	-
OR1J1	347168	olfactory receptor, family 1, subfamily J, member 1	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
OAZ3	51686	ornithine decarboxylase antizyme 3	small molecule metabolic process	Biological process	-
LILRB5	10990	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5	defense response	Biological process	9548455
TNFRSF25	8718	tumor necrosis factor receptor superfamily, member 25	tumor necrosis factor-mediated signaling pathway	Biological process	9052839
KRTAP4-8	728224	keratin associated protein 4-8	keratin filament	Cellular component	-
HOXA4	3201	homeobox A4	anterior/posterior pattern specification	Biological process	-
AMOT	154796	angiomotin	establishment of cell polarity involved in ameboidal cell migration	Biological process	-
STXBP5	134957	syntaxin binding protein 5 (tomosyn)	regulation of gene expression	Biological process	21810271
IL26	55801	interleukin 26	cytosol	Cellular component	18483078
TMEM53	79639	transmembrane protein 53	integral component of membrane	Cellular component	-
SFRP1	6422	secreted frizzled-related protein 1	extracellular space	Cellular component	10980594
LTBR	4055	lymphotoxin beta receptor (TNFR superfamily, member 3)	protein binding	Molecular function	12393901
ICMT	23463	isoprenylcysteine carboxyl methyltransferase	in utero embryonic development	Biological process	-
TRIM26	7726	tripartite motif containing 26	negative regulation of viral entry into host cell	Biological process	18248090
OR52I2	143502	olfactory receptor, family 52, subfamily I, member 2	olfactory receptor activity	Molecular function	-
PDE4B	5142	phosphodiesterase 4B, cAMP-specific	cellular response to drug	Biological process	-
FGF19	9965	fibroblast growth factor 19	positive regulation of ERK1 and ERK2 cascade	Biological process	17623664
TLN2	83660	talin 2	actin cytoskeleton	Cellular component	10320934
NSD1	64324	nuclear receptor binding SET domain protein 1	chromosome	Cellular component	-
CXCR4	7852	chemokine (C-X-C motif) receptor 4	germ cell development	Biological process	-
CAT	847	catalase	hydrogen peroxide catabolic process	Biological process	18379038
PKD2	5311	polycystic kidney disease 2 (autosomal dominant)	metanephric part of ureteric bud development	Biological process	11891195
GTF2I	2969	general transcription factor IIi	neuronal cell body	Cellular component	-
LHX9	56956	LIM homeobox 9	protein binding	Molecular function	25416956
IPO11	51194	importin 11	ribosomal protein import into nucleus	Biological process	-
MYH4	4622	myosin, heavy chain 4, skeletal muscle	sarcomere	Cellular component	3904738
ODC1	4953	ornithine decarboxylase 1	cytoplasm	Cellular component	-
NDUFB11	54539	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa	respiratory electron transport chain	Biological process	-
MARVELD2	153562	MARVEL domain containing 2	bicellular tight junction	Cellular component	20164257
ASAP2	8853	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	enzyme activator activity	Molecular function	9819391
HDAC6	10013	histone deacetylase 6	misfolded protein binding	Molecular function	-
HMGN5	79366	high mobility group nucleosome binding domain 5	nucleus	Cellular component	11161810
CRYAA	1409	crystallin, alpha A	structural constituent of eye lens	Molecular function	-
HENMT1	113802	HEN1 methyltransferase homolog 1 (Arabidopsis)	gene silencing by RNA	Biological process	-
QARS	5859	glutaminyl-tRNA synthetase	ATP binding	Molecular function	-
SPTBN1	6711	spectrin, beta, non-erythrocytic 1	nucleolus	Cellular component	9537418
NPHP3	27031	nephronophthisis 3 (adolescent)	convergent extension involved in gastrulation	Biological process	18371931
SERPINE2	5270	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2	protein binding	Molecular function	19911255
ATP7A	538	ATPase, Cu++ transporting, alpha polypeptide	release of cytochrome c from mitochondria	Biological process	-
GRHL3	57822	grainyhead-like 3 (Drosophila)	chromatin DNA binding	Molecular function	21081122
HTR2A	3356	5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled	detection of temperature stimulus involved in sensory perception of pain	Biological process	-
NOD1	10392	nucleotide-binding oligomerization domain containing 1	positive regulation of dendritic cell antigen processing and presentation	Biological process	-
LLGL1	3996	lethal giant larvae homolog 1 (Drosophila)	axon	Cellular component	-
DRP2	1821	dystrophin related protein 2	cytoskeleton	Cellular component	-
TDRP	157695	testis development related protein	molecular_function	Molecular function	-
FOXP3	50943	forkhead box P3	response to virus	Biological process	20583921
P4HA1	5033	prolyl 4-hydroxylase, alpha polypeptide I	mitochondrion	Cellular component	-
MAPK11	5600	mitogen-activated protein kinase 11	stress-activated MAPK cascade	Biological process	-
CHST5	23563	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5	keratan sulfate biosynthetic process	Biological process	-
STX6	10228	syntaxin 6	protein binding	Molecular function	11384996
SMAD3	4088	SMAD family member 3	cytoplasm	Cellular component	-
APOE	348	apolipoprotein E	high-density lipoprotein particle assembly	Biological process	17305370
LIG1	3978	ligase I, DNA, ATP-dependent	response to hydrogen peroxide	Biological process	-
TBC1D9B	23061	TBC1 domain family, member 9B (with GRAM domain)	GTPase activator activity	Molecular function	-
RAB35	11021	RAB35, member RAS oncogene family	plasma membrane to endosome transport	Biological process	17562788
FAP	2191	fibroblast activation protein, alpha	apical part of cell	Cellular component	-
OR8H2	390151	olfactory receptor, family 8, subfamily H, member 2	sensory perception of smell	Biological process	-
ITSN1	6453	intersectin 1 (SH3 domain protein)	calcium ion binding	Molecular function	9799604
UBB	7314	ubiquitin B	I-kappaB kinase/NF-kappaB signaling	Biological process	-
GAL3ST2	64090	galactose-3-O-sulfotransferase 2	Golgi cisterna membrane	Cellular component	-
CUL9	23113	cullin 9	zinc ion binding	Molecular function	-
ITGA5	3678	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	blood coagulation	Biological process	-
TUBB2B	347733	tubulin, beta 2B class IIb	'de novo' posttranslational protein folding	Biological process	-
SOAT2	8435	sterol O-acyltransferase 2	intestinal cholesterol absorption	Biological process	14615411
FKBP4	2288	FK506 binding protein 4, 59kDa	heat shock protein binding	Molecular function	9660753
GNRH1	2796	gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)	extracellular region	Cellular component	-
TATDN2	9797	TatD DNase domain containing 2	metal ion binding	Molecular function	-
PLCB4	5332	phospholipase C, beta 4	phosphatidylinositol phospholipase C activity	Molecular function	-
KRT28	162605	keratin 28, type I	intermediate filament	Cellular component	-
PCDHB8	56128	protocadherin beta 8	integral component of membrane	Cellular component	-
REL	5966	v-rel avian reticuloendotheliosis viral oncogene homolog	I-kappaB kinase/NF-kappaB signaling	Biological process	-
CALCOCO2	10241	calcium binding and coiled-coil domain 2	cytoskeleton	Cellular component	-
USP21	27005	ubiquitin specific peptidase 21	cytoplasm	Cellular component	-
ZNF569	148266	zinc finger protein 569	protein binding	Molecular function	25416956
GRK7	131890	G protein-coupled receptor kinase 7	termination of G-protein coupled receptor signaling pathway	Biological process	-
NDUFV1	4723	NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa	NADH dehydrogenase (ubiquinone) activity	Molecular function	8288251
SOX3	6658	SRY (sex determining region Y)-box 3	sequence-specific DNA binding transcription factor activity	Molecular function	-
SHROOM2	357	shroom family member 2	melanosome organization	Biological process	-
SYT10	341359	synaptotagmin X	integral component of membrane	Cellular component	-
SIRT6	51548	sirtuin 6	NAD+ binding	Molecular function	-
NLGN3	54413	neuroligin 3	protein binding	Molecular function	17292328
VEGFA	7422	vascular endothelial growth factor A	positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway	Biological process	18440775
MRPS25	64432	mitochondrial ribosomal protein S25	mitochondrion	Cellular component	-
CHSY1	22856	chondroitin sulfate synthase 1	extracellular region	Cellular component	21129727
CPSF1	29894	cleavage and polyadenylation specific factor 1, 160kDa	mRNA 3'-UTR binding	Molecular function	7590244
TRPM3	80036	transient receptor potential cation channel, subfamily M, member 3	calcium channel activity	Molecular function	-
LAMA5	3911	laminin, alpha 5	muscle organ development	Biological process	-
SEC23A	10484	Sec23 homolog A (S. cerevisiae)	COPII vesicle coat	Cellular component	-
MAP3K11	4296	mitogen-activated protein kinase kinase kinase 11	JUN kinase kinase kinase activity	Molecular function	-
CDCA3	83461	cell division cycle associated 3	cellular_component	Cellular component	-
CCL3L3	414062	chemokine (C-C motif) ligand 3-like 3	chemokine activity	Molecular function	-
KCNG2	26251	potassium channel, voltage gated modifier subfamily G, member 2	voltage-gated potassium channel complex	Cellular component	-
HSPA8	3312	heat shock 70kDa protein 8	ATP metabolic process	Biological process	23921388
P2RX7	5027	purinergic receptor P2X, ligand gated ion channel, 7	multicellular organismal protein catabolic process	Biological process	-
ZCCHC17	51538	zinc finger, CCHC domain containing 17	nucleus	Cellular component	-
TMEM219	124446	transmembrane protein 219	integral component of membrane	Cellular component	-
KHDRBS1	10657	KH domain containing, RNA binding, signal transduction associated 1	SH3 domain binding	Molecular function	-
MYLK	4638	myosin light chain kinase	aorta smooth muscle tissue morphogenesis	Biological process	21055718
RYR1	6261	ryanodine receptor 1 (skeletal)	outflow tract morphogenesis	Biological process	-
TAF7	6879	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa	transcription from RNA polymerase II promoter	Biological process	7824954
ZNF740	283337	zinc finger protein 740	nucleus	Cellular component	-
PTK2	5747	protein tyrosine kinase 2	extrinsic component of cytoplasmic side of plasma membrane	Cellular component	-
GNB2L1	10399	guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1	protein phosphatase binding	Molecular function	11278757
HGF	3082	hepatocyte growth factor (hepapoietin A; scatter factor)	mitotic nuclear division	Biological process	2531289
HHIP	64399	hedgehog interacting protein	dorsal/ventral pattern formation	Biological process	-
MARK2	2011	MAP/microtubule affinity-regulating kinase 2	plasma membrane	Cellular component	23902687
TACR1	6869	tachykinin receptor 1	response to ethanol	Biological process	-
IFITM1	8519	interferon induced transmembrane protein 1	intracellular	Cellular component	7559564
UBE2L6	9246	ubiquitin-conjugating enzyme E2L 6	protein ubiquitination	Biological process	-
ITGB2	3689	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	protein kinase binding	Molecular function	12885943
TAF1D	79101	TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa	RNA polymerase transcription factor SL1 complex	Cellular component	-
SPOCK1	6695	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1	negative regulation of endopeptidase activity	Biological process	14511383
MYL1	4632	myosin, light chain 1, alkali; skeletal, fast	muscle filament sliding	Biological process	-
DYNC1I1	1780	dynein, cytoplasmic 1, intermediate chain 1	microtubule binding	Molecular function	-
NSUN6	221078	NOP2/Sun domain family, member 6	methylation	Biological process	-
PRKCQ	5588	protein kinase C, theta	membrane protein ectodomain proteolysis	Biological process	-
RHCG	51458	Rh family, C glycoprotein	amine transport	Biological process	10852913
CRLF1	9244	cytokine receptor-like factor 1	negative regulation of motor neuron apoptotic process	Biological process	-
TNIP1	10318	TNFAIP3 interacting protein 1	defense response	Biological process	9923610
CYP4F11	57834	cytochrome P450, family 4, subfamily F, polypeptide 11	heme binding	Molecular function	10964514
GTF2E1	2960	general transcription factor IIE, polypeptide 1, alpha 56kDa	intermediate filament cytoskeleton	Cellular component	-
DNAJC16	23341	DnaJ (Hsp40) homolog, subfamily C, member 16	cell	Cellular component	-
RUNX2	860	runt-related transcription factor 2	regulation of fibroblast growth factor receptor signaling pathway	Biological process	-
C12orf66	144577	chromosome 12 open reading frame 66	microtubule cytoskeleton	Cellular component	-
F2RL1	2150	coagulation factor II (thrombin) receptor-like 1	defense response to virus	Biological process	18453611
PAPD7	11044	PAP associated domain containing 7	cell division	Biological process	-
STX4	6810	syntaxin 4	perinuclear region of cytoplasm	Cellular component	-
NGLY1	55768	N-glycanase 1	metal ion binding	Molecular function	-
DAB2	1601	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)	Wnt signaling pathway	Biological process	-
BLVRB	645	biliverdin reductase B	oxidation-reduction process	Biological process	-
WNT10A	80326	wingless-type MMTV integration site family, member 10A	cell fate commitment	Biological process	-
USP24	23358	ubiquitin specific peptidase 24	ubiquitin-specific protease activity	Molecular function	-
FGF4	2249	fibroblast growth factor 4	mesenchymal cell proliferation	Biological process	11023873
SSTR2	6752	somatostatin receptor 2	plasma membrane	Cellular component	-
VCPKMT	79609	valosin containing protein lysine (K) methyltransferase	peptidyl-lysine trimethylation	Biological process	22948820
VIMP	55829	VCP-interacting membrane selenoprotein	negative regulation of glucose import	Biological process	12663463
IL33	90865	interleukin 33	positive regulation of type 2 immune response	Biological process	-
ETV1	2115	ets variant 1	nucleus	Cellular component	-
IQGAP1	8826	IQ motif containing GTPase activating protein 1	neuron projection extension	Biological process	15695813
PKD1	5310	polycystic kidney disease 1 (autosomal dominant)	basolateral plasma membrane	Cellular component	10770959
FAS	355	Fas cell surface death receptor	regulation of necrotic cell death	Biological process	-
AKR1B1	231	aldo-keto reductase family 1, member B1 (aldose reductase)	response to stress	Biological process	8435445
F9	2158	coagulation factor IX	proteolysis	Biological process	-
RPS23	6228	ribosomal protein S23	SRP-dependent cotranslational protein targeting to membrane	Biological process	-
SEPHS1	22929	selenophosphate synthetase 1	nuclear membrane	Cellular component	-
TMEM106C	79022	transmembrane protein 106C	protein binding	Molecular function	25416956
HSF1	3297	heat shock transcription factor 1	pronucleus	Cellular component	-
HYAL1	3373	hyaluronoglucosaminidase 1	response to antibiotic	Biological process	11944887
YTHDC2	64848	YTH domain containing 2	endoplasmic reticulum	Cellular component	21559518
GABRA5	2558	gamma-aminobutyric acid (GABA) A receptor, alpha 5	inner ear receptor cell development	Biological process	-
FOXM1	2305	forkhead box M1	DNA repair	Biological process	-
STXBP4	252983	syntaxin binding protein 4	protein stabilization	Biological process	19451233
GPR180	160897	G protein-coupled receptor 180	integral component of membrane	Cellular component	-
USP13	8975	ubiquitin specific peptidase 13 (isopeptidase T-3)	ubiquitin binding	Molecular function	21659512
SOX9	6662	SRY (sex determining region Y)-box 9	positive regulation of cartilage development	Biological process	21401405
ARNT	405	aryl hydrocarbon receptor nuclear translocator	enhancer binding	Molecular function	23275542
UBE2W	55284	ubiquitin-conjugating enzyme E2W (putative)	protein monoubiquitination	Biological process	21229326
COL14A1	7373	collagen, type XIV, alpha 1	proteinaceous extracellular matrix	Cellular component	2187872
SEMA3A	10371	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	regulation of axon extension involved in axon guidance	Biological process	18053124
BGLAP	632	bone gamma-carboxyglutamate (gla) protein	response to gravity	Biological process	-
UGT3A2	167127	UDP glycosyltransferase 3 family, polypeptide A2	integral component of membrane	Cellular component	-
IL5RA	3568	interleukin 5 receptor, alpha	plasma membrane	Cellular component	-
HDAC4	9759	histone deacetylase 4	nucleoplasm	Cellular component	-
TENM4	26011	teneurin transmembrane protein 4	cytoplasm	Cellular component	-
KRT19	3880	keratin 19, type I	sarcomere organization	Biological process	16000376
TMC5	79838	transmembrane channel-like 5	extracellular exosome	Cellular component	23533145
ABI1	10006	abl-interactor 1	cytoskeleton	Cellular component	-
HIPK3	10114	homeodomain interacting protein kinase 3	apoptotic process	Biological process	-
IGKV3D-20	28874	immunoglobulin kappa variable 3D-20	antigen binding	Molecular function	5027703
BCL11B	64919	B-cell CLL/lymphoma 11B (zinc finger protein)	transcription, DNA-templated	Biological process	-
RIPK1	8737	receptor (TNFRSF)-interacting serine-threonine kinase 1	ripoptosome assembly involved in necroptotic process	Biological process	-
SUFU	51684	suppressor of fused homolog (Drosophila)	protein binding	Molecular function	10564661
SFPQ	6421	splicing factor proline/glutamine-rich	regulation of circadian rhythm	Biological process	-
C19orf44	84167	chromosome 19 open reading frame 44	protein binding	Molecular function	25416956
SLC32A1	140679	solute carrier family 32 (GABA vesicular transporter), member 1	clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane	Cellular component	-
NAPA	8775	N-ethylmaleimide-sensitive factor attachment protein, alpha	protein binding	Molecular function	15029241
PRB3	5544	proline-rich protein BstNI subfamily 3	defense response to Gram-negative bacterium	Biological process	1894623
HOXA11	3207	homeobox A11	cartilage development involved in endochondral bone morphogenesis	Biological process	-
ABLIM3	22885	actin binding LIM protein family, member 3	cilium assembly	Biological process	22684256
LYN	4067	LYN proto-oncogene, Src family tyrosine kinase	positive regulation of cell proliferation	Biological process	-
TMPRSS5	80975	transmembrane protease, serine 5	scavenger receptor activity	Molecular function	-
IL6ST	3572	interleukin 6 signal transducer	interleukin-6 receptor complex	Cellular component	12643274
BPIFA1	51297	BPI fold containing family A, member 1	extracellular space	Cellular component	24124190
RORA	6095	RAR-related orphan receptor A	beta-catenin binding	Molecular function	-
NCOA3	8202	nuclear receptor coactivator 3	signal transducer activity	Molecular function	-
GHRHR	2692	growth hormone releasing hormone receptor	secretory granule	Cellular component	10461027
ATP13A5	344905	ATPase type 13A5	plasma membrane	Cellular component	-
RABL2A	11159	RAB, member of RAS oncogene family-like 2A	protein binding	Molecular function	25416956
NR1H4	9971	nuclear receptor subfamily 1, group H, member 4	intracellular receptor signaling pathway	Biological process	-
COMMD2	51122	COMM domain containing 2	regulation of transcription, DNA-templated	Biological process	-
CPNE6	9362	copine VI (neuronal)	dendrite	Cellular component	-
SSTR5	6755	somatostatin receptor 5	plasma membrane	Cellular component	-
ATP6V0C	527	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c	insulin receptor signaling pathway	Biological process	-
MICA	100507436	MHC class I polypeptide-related sequence A	negative regulation of natural killer cell mediated cytotoxicity	Biological process	20068167
MMP17	4326	matrix metallopeptidase 17 (membrane-inserted)	proteinaceous extracellular matrix	Cellular component	-
CDK5R2	8941	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	cyclin-dependent protein kinase 5 holoenzyme complex	Cellular component	-
IL1B	3553	interleukin 1, beta	protein domain specific binding	Molecular function	16575408
PDCL3	79031	phosducin-like 3	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	23792958
PRKD2	25865	protein kinase D2	cell death	Biological process	17077180
ZNF701	55762	zinc finger protein 701	regulation of transcription, DNA-templated	Biological process	-
WIPF2	147179	WAS/WASL interacting protein family, member 2	actin binding	Molecular function	-
MYOCD	93649	myocardin	transcription factor binding	Molecular function	16054032
SOX9	6662	SRY (sex determining region Y)-box 9	negative regulation of myoblast differentiation	Biological process	-
SERPINF2	5345	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2	cell surface	Cellular component	17958745
CFL1	1072	cofilin 1 (non-muscle)	mitotic cytokinesis	Biological process	-
AKR1C3	8644	aldo-keto reductase family 1, member C3	farnesol catabolic process	Biological process	21187079
PHYKPL	85007	5-phosphohydroxy-L-lysine phospho-lyase	mitochondrion	Cellular component	-
SLC2A9	56606	solute carrier family 2 (facilitated glucose transporter), member 9	glucose transmembrane transporter activity	Molecular function	-
SEMA5A	9037	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	positive regulation of axon extension involved in axon guidance	Biological process	-
PGR	5241	progesterone receptor	progesterone receptor signaling pathway	Biological process	-
KCNH1	3756	potassium channel, voltage gated eag related subfamily H, member 1	integral component of plasma membrane	Cellular component	22732247
LCK	3932	LCK proto-oncogene, Src family tyrosine kinase	peptidyl-tyrosine autophosphorylation	Biological process	-
SCN8A	6334	sodium channel, voltage gated, type VIII alpha subunit	neuronal cell body	Cellular component	-
CENPU	79682	centromere protein U	cytosol	Cellular component	-
FOXD4L5	653427	forkhead box D4-like 5	cell differentiation	Biological process	-
FCMR	9214	Fc fragment of IgM receptor	cellular defense response	Biological process	9586636
POLRMT	5442	polymerase (RNA) mitochondrial (DNA directed)	transcription from mitochondrial promoter	Biological process	17337445
CPT1A	1374	carnitine palmitoyltransferase 1A (liver)	integral component of mitochondrial outer membrane	Cellular component	-
DNM2	1785	dynamin 2	negative regulation of membrane tubulation	Biological process	18388313
NISCH	11188	nischarin	early endosome	Cellular component	-
MAG	4099	myelin associated glycoprotein	substantia nigra development	Biological process	22926577
RAB14	51552	RAB14, member RAS oncogene family	intracellular transport	Biological process	15004230
JUN	3725	jun proto-oncogene	learning	Biological process	-
AASDH	132949	aminoadipate-semialdehyde dehydrogenase	acid-thiol ligase activity	Molecular function	-
H3F3A	3020	H3 histone, family 3A	protein binding	Molecular function	19494831
IGF2	3481	insulin-like growth factor 2	protein serine/threonine kinase activator activity	Molecular function	-
TMEM115	11070	transmembrane protein 115	Golgi apparatus	Cellular component	17973242
KRT13	3860	keratin 13, type I	keratin filament	Cellular component	9714826
CALM3	808	calmodulin 3 (phosphorylase kinase, delta)	regulation of cell communication by electrical coupling involved in cardiac conduction	Biological process	-
PABPC4	8761	poly(A) binding protein, cytoplasmic 4 (inducible form)	poly(C) RNA binding	Molecular function	8524242
AMY1A	276	amylase, alpha 1A (salivary)	extracellular exosome	Cellular component	19199708
VARS2	57176	valyl-tRNA synthetase 2, mitochondrial	cytosol	Cellular component	-
RARA	5914	retinoic acid receptor, alpha	nuclear chromatin	Cellular component	17363140
MSLN	10232	mesothelin	extracellular space	Cellular component	-
GNAS	2778	GNAS complex locus	renal water homeostasis	Biological process	-
TAF1B	9014	TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa	TBP-class protein binding	Molecular function	21921199
SFTPB	6439	surfactant protein B	organ morphogenesis	Biological process	10378403
LRRC52	440699	leucine rich repeat containing 52	ion transport	Biological process	-
JUP	3728	junction plakoglobin	protein homodimerization activity	Molecular function	-
CFAP43	80217	cilia and flagella associated protein 43	cell projection	Cellular component	-
MAP1S	55201	microtubule-associated protein 1S	microtubule bundle formation	Biological process	15528209
GFI1	2672	growth factor independent 1 transcription repressor	auditory receptor cell differentiation	Biological process	-
RIPK1	8737	receptor (TNFRSF)-interacting serine-threonine kinase 1	protein autophosphorylation	Biological process	8612133
PAOX	196743	polyamine oxidase (exo-N4-amino)	putrescine biosynthetic process	Biological process	16354669
SCN1B	6324	sodium channel, voltage gated, type I beta subunit	regulation of heart rate by cardiac conduction	Biological process	19808477
CRYAB	1410	crystallin, alpha B	protein folding	Biological process	-
RBMX	27316	RNA binding motif protein, X-linked	nucleotide binding	Molecular function	-
HIST1H3I	8354	histone cluster 1, H3i	DNA binding	Molecular function	-
SOCS3	9021	suppressor of cytokine signaling 3	spongiotrophoblast differentiation	Biological process	-
RASA4	10156	RAS p21 protein activator 4	positive regulation of GTPase activity	Biological process	-
VHL	7428	von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase	positive regulation of cell differentiation	Biological process	12169691
HOXA10	3206	homeobox A10	transcription, DNA-templated	Biological process	-
GATA4	2626	GATA binding protein 4	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	-
MAP2	4133	microtubule-associated protein 2	microtubule	Cellular component	-
PLCB1	23236	phospholipase C, beta 1 (phosphoinositide-specific)	interleukin-15-mediated signaling pathway	Biological process	11743656
UBC	7316	ubiquitin C	carbohydrate metabolic process	Biological process	-
CCL25	6370	chemokine (C-C motif) ligand 25	chemotaxis	Biological process	10640743
NR1H3	10062	nuclear receptor subfamily 1, group H, member 3	positive regulation of fatty acid biosynthetic process	Biological process	17186944
TLR10	81793	toll-like receptor 10	toll-like receptor 5 signaling pathway	Biological process	-
NOVA1	4857	neuro-oncological ventral antigen 1	synaptic transmission	Biological process	8558240
RET	5979	ret proto-oncogene	signal transduction	Biological process	7824936
ID4	3400	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	circadian rhythm	Biological process	-
SRRT	51593	serrate, RNA effector molecule	primary miRNA processing	Biological process	19632182
NFATC1	4772	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	FK506 binding	Molecular function	8702849
PPM1E	22843	protein phosphatase, Mg2+/Mn2+ dependent, 1E	nucleolus	Cellular component	-
HSPB2	3316	heat shock 27kDa protein 2	cytosol	Cellular component	9490724
MTRF1L	54516	mitochondrial translational release factor 1-like	mitochondrial matrix	Cellular component	-
PTPN22	26191	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	negative regulation of T cell activation	Biological process	18299186
CHUK	1147	conserved helix-loop-helix ubiquitous kinase	inflammatory response	Biological process	18626576
S1PR1	1901	sphingosine-1-phosphate receptor 1	sphingolipid binding	Molecular function	-
DDX60	55601	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	protein binding	Molecular function	21791617
F8	2157	coagulation factor VIII, procoagulant component	proteolysis	Biological process	-
STK36	27148	serine/threonine kinase 36	epithelial cilium movement	Biological process	-
NFATC2	4773	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
ADAMTS16	170690	ADAM metallopeptidase with thrombospondin type 1 motif, 16	metalloendopeptidase activity	Molecular function	-
RAB9A	9367	RAB9A, member RAS oncogene family	plasma membrane	Cellular component	-
ACTG1	71	actin gamma 1	plasma membrane	Cellular component	-
CENPW	387103	centromere protein W	protein heterodimerization activity	Molecular function	-
EIF3I	8668	eukaryotic translation initiation factor 3, subunit I	formation of translation preinitiation complex	Biological process	-
TOX3	27324	TOX high mobility group box family member 3	transcription, DNA-templated	Biological process	-
KL	9365	klotho	energy reserve metabolic process	Biological process	-
MOV10	4343	Mov10 RISC complex RNA helicase	poly(A) RNA binding	Molecular function	22658674
CNGA1	1259	cyclic nucleotide gated channel alpha 1	potassium ion transmembrane transport	Biological process	-
CACNA1D	776	calcium channel, voltage-dependent, L type, alpha 1D subunit	regulation of heart rate by cardiac conduction	Biological process	21131953
AOC3	8639	amine oxidase, copper containing 3	calcium ion binding	Molecular function	19764817
CYP2D6	1565	cytochrome P450, family 2, subfamily D, polypeptide 6	xenobiotic metabolic process	Biological process	19438707
RRAGC	64121	Ras-related GTP binding C	intracellular membrane-bounded organelle	Cellular component	-
MTA1	9112	metastasis associated 1	core promoter binding	Molecular function	21965678
DNMT3A	1788	DNA (cytosine-5-)-methyltransferase 3 alpha	cytoplasm	Cellular component	12138111
HIST2H3D	653604	histone cluster 2, H3d	blood coagulation	Biological process	-
NPM1	4869	nucleophosmin (nucleolar phosphoprotein B23, numatrin)	intracellular protein transport	Biological process	12080348
GREM1	26585	gremlin 1, DAN family BMP antagonist	cell surface	Cellular component	-
KDM5A	5927	lysine (K)-specific demethylase 5A	transcription from RNA polymerase II promoter	Biological process	8414517
TGFBR1	7046	transforming growth factor, beta receptor 1	ATP binding	Molecular function	12065756
RBX1	9978	ring-box 1, E3 ubiquitin protein ligase	Cul4A-RING E3 ubiquitin ligase complex	Cellular component	12732143
HAS3	3038	hyaluronan synthase 3	glycosaminoglycan metabolic process	Biological process	-
HIST1H2AI	8329	histone cluster 1, H2ai	enzyme binding	Molecular function	17980597
SLC39A14	23516	solute carrier family 39 (zinc transporter), member 14	zinc ion transmembrane transporter activity	Molecular function	15642354
MSH3	4437	mutS homolog 3	somatic recombination of immunoglobulin gene segments	Biological process	-
TAF4	6874	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa	transcription initiation from RNA polymerase II promoter	Biological process	-
SERPINE2	5270	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2	detection of mechanical stimulus involved in sensory perception	Biological process	-
CSTF1	1477	cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa	poly(A) RNA binding	Molecular function	22658674
ZNF678	339500	zinc finger protein 678	regulation of transcription, DNA-templated	Biological process	-
CHRM1	1128	cholinergic receptor, muscarinic 1	nervous system development	Biological process	2739737
XPO1	7514	exportin 1	transporter activity	Molecular function	-
GSK3B	2932	glycogen synthase kinase 3 beta	nucleoplasm	Cellular component	-
TBC1D3	729873	TBC1 domain family, member 3	regulation of cilium assembly	Biological process	17646400
PCNT	5116	pericentrin	centriole	Cellular component	24421332
ZSCAN23	222696	zinc finger and SCAN domain containing 23	transcription, DNA-templated	Biological process	-
ATM	472	ATM serine/threonine kinase	V(D)J recombination	Biological process	-
USP17L8	392188	ubiquitin specific peptidase 17-like family member 8	ubiquitinyl hydrolase activity	Molecular function	-
SEC24B	10427	SEC24 family member B	COPII vesicle coating	Biological process	-
RETN	56729	resistin	positive regulation of collagen metabolic process	Biological process	-
FAM74A4	401508	family with sequence similarity 74, member A4	protein binding	Molecular function	25416956
FOXF1	2294	forkhead box F1	smooth muscle cell differentiation	Biological process	-
POR	5447	P450 (cytochrome) oxidoreductase	nitric oxide dioxygenase activity	Molecular function	-
NR2C1	7181	nuclear receptor subfamily 2, group C, member 1	zinc ion binding	Molecular function	-
DLG4	1742	discs, large homolog 4 (Drosophila)	PDZ domain binding	Molecular function	-
RAD51C	5889	RAD51 paralog C	positive regulation of G2/M transition of mitotic cell cycle	Biological process	23108668
TNF	7124	tumor necrosis factor	negative regulation of gene expression	Biological process	15345745
NAA10	8260	N(alpha)-acetyltransferase 10, NatA catalytic subunit	N-terminal peptidyl-glutamic acid acetylation	Biological process	-
CLDN19	149461	claudin 19	cytoplasm	Cellular component	-
ACPP	55	acid phosphatase, prostate	purine nucleobase metabolic process	Biological process	-
GORAB	92344	golgin, RAB6-interacting	nucleolus	Cellular component	-
IL18	3606	interleukin 18	immune response	Biological process	8999896
NPFFR2	10886	neuropeptide FF receptor 2	neuropeptide receptor activity	Molecular function	-
SNX33	257364	sorting nexin 33	cleavage furrow formation	Biological process	22718350
ARHGEF2	9181	Rho/Rac guanine nucleotide exchange factor (GEF) 2	positive regulation of NF-kappaB transcription factor activity	Biological process	19043560
RORB	6096	RAR-related orphan receptor B	retinal rod cell development	Biological process	-
BRK1	55845	BRICK1, SCAR/WAVE actin-nucleating complex subunit	cytosol	Cellular component	-
PTGIS	5740	prostaglandin I2 (prostacyclin) synthase	apoptotic signaling pathway	Biological process	11551955
CPLX4	339302	complexin 4	cell	Cellular component	-
IGHV3-23	28442	immunoglobulin heavy variable 3-23	Fc-gamma receptor signaling pathway involved in phagocytosis	Biological process	-
VRK3	51231	vaccinia related kinase 3	protein phosphatase binding	Molecular function	22572157
MORF4L2	9643	mortality factor 4 like 2	positive regulation of striated muscle cell differentiation	Biological process	-
SDPR	8436	serum deprivation response	cytosol	Cellular component	2390065
FURIN	5045	furin (paired basic amino acid cleaving enzyme)	peptide hormone processing	Biological process	9242664
NELL2	4753	NEL-like 2 (chicken)	calcium ion binding	Molecular function	-
SLIT2	9353	slit homolog 2 (Drosophila)	mammary duct terminal end bud growth	Biological process	-
PFDN6	10471	prefoldin subunit 6	'de novo' posttranslational protein folding	Biological process	-
OR52A5	390054	olfactory receptor, family 52, subfamily A, member 5	detection of chemical stimulus involved in sensory perception of smell	Biological process	11121057
SORBS1	10580	sorbin and SH3 domain containing 1	stress fiber assembly	Biological process	-
TGFB1	7040	transforming growth factor, beta 1	growth factor activity	Molecular function	-
SLC18A2	6571	solute carrier family 18 (vesicular monoamine transporter), member 2	synaptic transmission	Biological process	15217342
UBA3	9039	ubiquitin-like modifier activating enzyme 3	cellular protein modification process	Biological process	9694792
REPIN1	29803	replication initiator 1	cytosolic ribosome	Cellular component	-
ASPSCR1	79058	alveolar soft part sarcoma chromosome region, candidate 1	perinuclear region of cytoplasm	Cellular component	-
IGFL3	388555	IGF-like family member 3	extracellular region	Cellular component	-
CITED1	4435	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1	negative regulation of osteoblast differentiation	Biological process	-
RCL1	10171	RNA terminal phosphate cyclase-like 1	nucleolus	Cellular component	-
GNL2	29889	guanine nucleotide binding protein-like 2 (nucleolar)	nucleus	Cellular component	8822211
SPATA20	64847	spermatogenesis associated 20	cell differentiation	Biological process	-
SMAD3	4088	SMAD family member 3	embryonic cranial skeleton morphogenesis	Biological process	-
THOC1	9984	THO complex 1	nucleoplasm	Cellular component	-
KCNN3	3782	potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3	plasma membrane	Cellular component	-
TMEM192	201931	transmembrane protein 192	perinuclear region of cytoplasm	Cellular component	22736246
ZNF175	7728	zinc finger protein 175	intermediate filament cytoskeleton	Cellular component	-
CACYBP	27101	calcyclin binding protein	cellular response to calcium ion	Biological process	-
GGTLC2	91227	gamma-glutamyltransferase light chain 2	glutathione metabolic process	Biological process	18357469
PRKCE	5581	protein kinase C, epsilon	actin monomer binding	Molecular function	-
SELPLG	6404	selectin P ligand	leukocyte migration	Biological process	-
KRT12	3859	keratin 12, type I	epithelium development	Biological process	-
PRAMEF2	65122	PRAME family member 2	negative regulation of cell differentiation	Biological process	-
OXNAD1	92106	oxidoreductase NAD-binding domain containing 1	biological_process	Biological process	-
SPEF1	25876	sperm flagellar 1	biological_process	Biological process	-
HIC2	23119	hypermethylated in cancer 2	plasma membrane	Cellular component	-
TMEM63A	9725	transmembrane protein 63A	extracellular exosome	Cellular component	19056867
NME1	4830	NME/NM23 nucleoside diphosphate kinase 1	nucleoside triphosphate biosynthetic process	Biological process	-
HERC5	51191	HECT and RLD domain containing E3 ubiquitin protein ligase 5	defense response to virus	Biological process	-
DDX23	9416	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23	poly(A) RNA binding	Molecular function	22681889
HIST1H3J	8356	histone cluster 1, H3j	nucleosome assembly	Biological process	25615412
PGRMC1	10857	progesterone receptor membrane component 1	integral component of membrane	Cellular component	-
SIRT7	51547	sirtuin 7	NAD-dependent histone deacetylase activity (H3-K18 specific)	Molecular function	22722849
CXXC1	30827	CXXC finger protein 1	nucleus	Cellular component	-
DOCK2	1794	dedicator of cytokinesis 2	negative thymic T cell selection	Biological process	-
DST	667	dystonin	cytoskeleton organization	Biological process	19403692
PIK3R2	5296	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	epidermal growth factor receptor signaling pathway	Biological process	-
BACE1	23621	beta-site APP-cleaving enzyme 1	Golgi apparatus	Cellular component	10531052
RGS5	8490	regulator of G-protein signaling 5	cytoplasm	Cellular component	-
MGST1	4257	microsomal glutathione S-transferase 1	cellular response to lipid hydroperoxide	Biological process	20727966
TKFC	26007	triokinase/FMN cyclase	triokinase activity	Molecular function	4688871
GFI1	2672	growth factor independent 1 transcription repressor	negative regulation of transcription, DNA-templated	Biological process	12874834
Mar-01	55016	membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase	trans-Golgi network membrane	Cellular component	-
AKR1C8P	340811	aldo-keto reductase family 1, member C8, pseudogene	oxidation-reduction process	Biological process	-
NOX1	27035	NADPH oxidase 1	plasma membrane	Cellular component	-
HBEGF	1839	heparin-binding EGF-like growth factor	integral component of plasma membrane	Cellular component	15389565
C12orf4	57102	chromosome 12 open reading frame 4	regulation of mast cell degranulation	Biological process	-
INVS	27130	inversin	post-embryonic development	Biological process	-
SALL1	6299	spalt-like transcription factor 1	histone deacetylation	Biological process	-
SLC2A7	155184	solute carrier family 2 (facilitated glucose transporter), member 7	hexose transmembrane transport	Biological process	-
GGACT	87769	gamma-glutamylamine cyclotransferase	protein binding	Molecular function	25416956
FXN	2395	frataxin	positive regulation of cell growth	Biological process	15509595
MFF	56947	mitochondrial fission factor	cell junction	Cellular component	-
ABLIM3	22885	actin binding LIM protein family, member 3	lamellipodium assembly	Biological process	22684256
WDR5	11091	WD repeat domain 5	Set1C/COMPASS complex	Cellular component	17998332
HPRT1	3251	hypoxanthine phosphoribosyltransferase 1	cytosol	Cellular component	-
RAD51B	5890	RAD51 paralog B	nucleus	Cellular component	9512535
SNX9	51429	sorting nexin 9	endocytosis	Biological process	22718350
SLC3A1	6519	solute carrier family 3 (amino acid transporter heavy chain), member 1	plasma membrane	Cellular component	-
NDC1	55706	NDC1 transmembrane nucleoporin	membrane	Cellular component	19946888
CCNB2	9133	cyclin B2	in utero embryonic development	Biological process	-
RAD51B	5890	RAD51 paralog B	reciprocal meiotic recombination	Biological process	9441753
IGHMBP2	3508	immunoglobulin mu binding protein 2	ATP binding	Molecular function	19158098
OAS1	4938	2'-5'-oligoadenylate synthetase 1, 40/46kDa	negative regulation of viral genome replication	Biological process	18931074
USB1	79650	U6 snRNA biogenesis 1	3'-5'-exoribonuclease activity	Molecular function	23190533
BBS4	585	Bardet-Biedl syndrome 4	beta-tubulin binding	Molecular function	17574030
GNL3L	54552	guanine nucleotide binding protein-like 3 (nucleolar)-like	ribosome biogenesis	Biological process	-
RREB1	6239	ras responsive element binding protein 1	cytoplasm	Cellular component	9305772
USP17L2	377630	ubiquitin specific peptidase 17-like family member 2	regulation of cell proliferation	Biological process	19188362
MGAT2	4247	mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	post-translational protein modification	Biological process	-
ARHGDIB	397	Rho GDP dissociation inhibitor (GDI) beta	multicellular organismal development	Biological process	8434008
CSGALNACT1	55790	chondroitin sulfate N-acetylgalactosaminyltransferase 1	metal ion binding	Molecular function	12163485
GCG	2641	glucagon	small molecule metabolic process	Biological process	-
SNCA	6622	synuclein, alpha (non A4 component of amyloid precursor)	microtubule binding	Molecular function	-
SCN4B	6330	sodium channel, voltage gated, type IV beta subunit	regulation of sodium ion transmembrane transporter activity	Biological process	17592081
YEATS2	55689	YEATS domain containing 2	chromatin organization	Biological process	-
RAC1	5879	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	positive regulation of substrate adhesion-dependent cell spreading	Biological process	23129259
YWHAG	7532	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma	protein kinase C binding	Molecular function	10433554
SLC43A1	8501	solute carrier family 43 (amino acid system L transporter), member 1	integral component of plasma membrane	Cellular component	12930836
ERGIC1	57222	endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1	endoplasmic reticulum-Golgi intermediate compartment membrane	Cellular component	-
AIMP1	9255	aminoacyl tRNA synthetase complex-interacting multifunctional protein 1	chemotaxis	Biological process	7545917
DDC	1644	dopa decarboxylase (aromatic L-amino acid decarboxylase)	cellular response to alkaloid	Biological process	-
TIMM23	100287932	translocase of inner mitochondrial membrane 23 homolog (yeast)	mitochondrial inner membrane	Cellular component	14726512
TGFBR1	7046	transforming growth factor, beta receptor 1	activin receptor signaling pathway	Biological process	-
CASK	8573	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	extracellular matrix organization	Biological process	-
FMNL1	752	formin-like 1	plasma membrane	Cellular component	-
SRGN	5552	serglycin	platelet activation	Biological process	-
CLEC4A	50856	C-type lectin domain family 4, member A	transmembrane signaling receptor activity	Molecular function	10438934
CAMK2G	818	calcium/calmodulin-dependent protein kinase II gamma	regulation of calcium ion transport	Biological process	15294044
HLA-DQB2	3120	major histocompatibility complex, class II, DQ beta 2	antigen processing and presentation of exogenous peptide antigen via MHC class II	Biological process	-
SETDB2	83852	SET domain, bifurcated 2	protein binding	Molecular function	25416956
TRIM38	10475	tripartite motif containing 38	signal transducer activity	Molecular function	12761501
CLDN16	10686	claudin 16	integral component of membrane	Cellular component	-
SRMS	6725	src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites	non-membrane spanning protein tyrosine kinase activity	Molecular function	-
RNMT	8731	RNA (guanine-7-) methyltransferase	nucleoplasm	Cellular component	-
MDH2	4191	malate dehydrogenase 2, NAD (mitochondrial)	oxaloacetate metabolic process	Biological process	-
PSMD13	5719	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	Biological process	-
MICB	4277	MHC class I polypeptide-related sequence B	natural killer cell mediated cytotoxicity	Biological process	-
WNT11	7481	wingless-type MMTV integration site family, member 11	non-canonical Wnt signaling pathway	Biological process	-
METTL2A	339175	methyltransferase like 2A	tRNA methylation	Biological process	-
GAPDH	2597	glyceraldehyde-3-phosphate dehydrogenase	ribonucleoprotein complex	Cellular component	15479637
SMPD4	55627	sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)	trans-Golgi network	Cellular component	16517606
UCK1	83549	uridine-cytidine kinase 1	nucleobase-containing small molecule metabolic process	Biological process	-
LIPG	9388	lipase, endothelial	cholesterol homeostasis	Biological process	19136670
SAFB	6294	scaffold attachment factor B	hormone metabolic process	Biological process	-
CSF3R	1441	colony stimulating factor 3 receptor (granulocyte)	integral component of plasma membrane	Cellular component	7542747
IL2RB	3560	interleukin 2 receptor, beta	interleukin-2 binding	Molecular function	-
OR51B4	79339	olfactory receptor, family 51, subfamily B, member 4	G-protein coupled receptor activity	Molecular function	-
OR56B2P	390073	olfactory receptor, family 56, subfamily B, member 2 pseudogene	G-protein coupled receptor activity	Molecular function	-
ELOVL4	6785	ELOVL fatty acid elongase 4	fatty acid elongation, saturated fatty acid	Biological process	20937905
FABP4	2167	fatty acid binding protein 4, adipocyte	cytoplasm	Cellular component	16130169
ZAR1	326340	zygote arrest 1	cytoplasm	Cellular component	-
ASPSCR1	79058	alveolar soft part sarcoma chromosome region, candidate 1	extrinsic component of membrane	Cellular component	-
RORC	6097	RAR-related orphan receptor C	sequence-specific DNA binding	Molecular function	-
STAT3	6774	signal transducer and activator of transcription 3 (acute-phase response factor)	nervous system development	Biological process	10205054
EXOSC3	51010	exosome component 3	positive regulation of isotype switching	Biological process	-
DDIT4	54541	DNA-damage-inducible transcript 4	neurotrophin TRK receptor signaling pathway	Biological process	-
HNRNPA1	3178	heterogeneous nuclear ribonucleoprotein A1	RNA binding	Molecular function	8521471
LRP1	4035	low density lipoprotein receptor-related protein 1	positive regulation of protein transport	Biological process	-
KDM7A	80853	lysine (K)-specific demethylase 7A	histone H4-K20 demethylation	Biological process	20622853
PCM1	5108	pericentriolar material 1	intraciliary transport involved in cilium morphogenesis	Biological process	24550735
TRMT112	51504	tRNA methyltransferase 11-2 homolog (S. cerevisiae)	protein binding	Molecular function	18539146
MAPKAPK2	9261	mitogen-activated protein kinase-activated protein kinase 2	toll-like receptor 9 signaling pathway	Biological process	-
OR1D2	4991	olfactory receptor, family 1, subfamily D, member 2	olfactory receptor activity	Molecular function	12663925
LHPP	64077	phospholysine phosphohistidine inorganic pyrophosphate phosphatase	protein homodimerization activity	Molecular function	12801912
PRSS58	136541	protease, serine, 58	proteolysis	Biological process	-
CSTL1	128817	cystatin-like 1	cysteine-type endopeptidase inhibitor activity	Molecular function	-
CDKN1B	1027	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	negative regulation of kinase activity	Biological process	19170105
INSR	3643	insulin receptor	male sex determination	Biological process	-
AP1S3	130340	adaptor-related protein complex 1, sigma 3 subunit	regulation of defense response to virus by virus	Biological process	-
MANF	7873	mesencephalic astrocyte-derived neurotrophic factor	endoplasmic reticulum	Cellular component	-
DPYSL3	1809	dihydropyrimidinase-like 3	response to axon injury	Biological process	-
RUNX1T1	862	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	cytoplasm	Cellular component	-
IMPDH1	3614	IMP (inosine 5'-monophosphate) dehydrogenase 1	GMP biosynthetic process	Biological process	-
MLYCD	23417	malonyl-CoA decarboxylase	mitochondrial matrix	Cellular component	-
GDF2	2658	growth differentiation factor 2	positive regulation of transcription, DNA-templated	Biological process	17068149
TRIM56	81844	tripartite motif containing 56	negative regulation of viral release from host cell	Biological process	-
ZNRD1	30834	zinc ribbon domain containing 1	nucleoplasm	Cellular component	-
EEPD1	80820	endonuclease/exonuclease/phosphatase family domain containing 1	DNA repair	Biological process	-
COQ3	51805	coenzyme Q3 methyltransferase	extrinsic component of mitochondrial inner membrane	Cellular component	-
SRA1	10011	steroid receptor RNA activator 1	intercellular bridge	Cellular component	-
DEFB123	245936	defensin, beta 123	extracellular region	Cellular component	-
BRCA2	675	breast cancer 2, early onset	secretory granule	Cellular component	8589722
WASL	8976	Wiskott-Aldrich syndrome-like	protein complex assembly	Biological process	9422512
CCT5	22948	chaperonin containing TCP1, subunit 5 (epsilon)	binding of sperm to zona pellucida	Biological process	-
RBM15B	29890	RNA binding motif protein 15B	nucleolus	Cellular component	16129689
KLRD1	3824	killer cell lectin-like receptor subfamily D, member 1	MHC class I protein complex binding	Molecular function	18448674
NYX	60506	nyctalopin	molecular_function	Molecular function	-
MAN2C1	4123	mannosidase, alpha, class 2C, member 1	alpha-mannosidase activity	Molecular function	-
KCNC3	3748	potassium channel, voltage gated Shaw related subfamily C, member 3	regulation of ion transmembrane transport	Biological process	-
STEAP1	26872	six transmembrane epithelial antigen of the prostate 1	metal ion binding	Molecular function	-
TNFRSF11B	4982	tumor necrosis factor receptor superfamily, member 11b	extracellular space	Cellular component	15516325
POLE	5426	polymerase (DNA directed), epsilon, catalytic subunit	telomere maintenance via recombination	Biological process	-
GFPT1	2673	glutamine--fructose-6-phosphate transaminase 1	cellular response to insulin stimulus	Biological process	-
HAUS4	54930	HAUS augmin-like complex, subunit 4	centrosome organization	Biological process	19427217
HIPK2	28996	homeodomain interacting protein kinase 2	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	Biological process	18974774
ULK4	54986	unc-51 like kinase 4	protein serine/threonine kinase activity	Molecular function	-
PARP8	79668	poly (ADP-ribose) polymerase family, member 8	intracellular	Cellular component	-
CD3E	916	CD3e molecule, epsilon (CD3-TCR complex)	SH3 domain binding	Molecular function	12110186
C4A	720	complement component 4A (Rodgers blood group)	positive regulation of apoptotic cell clearance	Biological process	19302245
KL	9365	klotho	positive regulation of bone mineralization	Biological process	12110410
TGM3	7053	transglutaminase 3	keratinization	Biological process	-
SLC12A3	6559	solute carrier family 12 (sodium/chloride transporter), member 3	transport	Biological process	8528245
NDUFS1	4719	NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)	respiratory electron transport chain	Biological process	-
TAF1A	9015	TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa	transcription from RNA polymerase I promoter	Biological process	-
HIST1H4H	8365	histone cluster 1, H4h	chromatin organization	Biological process	-
GDPD5	81544	glycerophosphodiester phosphodiesterase domain containing 5	positive regulation of neuron differentiation	Biological process	-
PCSK5	5125	proprotein convertase subtilisin/kexin type 5	embryonic skeletal system development	Biological process	8940009
CYP2D6	1565	cytochrome P450, family 2, subfamily D, polypeptide 6	oxygen binding	Molecular function	-
C1RL	51279	complement component 1, r subcomponent-like	innate immune response	Biological process	-
IFNGR1	3459	interferon gamma receptor 1	cytokine binding	Molecular function	-
SKA2	348235	spindle and kinetochore associated complex subunit 2	cytosol	Cellular component	-
SCN9A	6335	sodium channel, voltage gated, type IX alpha subunit	post-embryonic development	Biological process	-
BTG1	694	B-cell translocation gene 1, anti-proliferative	protein binding	Molecular function	10617598
RBL2	5934	retinoblastoma-like 2	regulation of lipid kinase activity	Biological process	16286473
SMC1A	8243	structural maintenance of chromosomes 1A	sister chromatid cohesion	Biological process	15917200
HECW2	57520	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2	cytoplasm	Cellular component	-
CHAC2	494143	ChaC, cation transport regulator homolog 2 (E. coli)	metabolic process	Biological process	-
HNRNPA0	10949	heterogeneous nuclear ribonucleoprotein A0	inflammatory response	Biological process	-
ZNF230	7773	zinc finger protein 230	metal ion binding	Molecular function	-
GRIN2A	2903	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	ion transmembrane transport	Biological process	-
WISP2	8839	WNT1 inducible signaling pathway protein 2	cell adhesion	Biological process	-
CHUK	1147	conserved helix-loop-helix ubiquitous kinase	MyD88-dependent toll-like receptor signaling pathway	Biological process	-
OR11L1	391189	olfactory receptor, family 11, subfamily L, member 1	molecular_function	Molecular function	-
TUBB6	84617	tubulin, beta 6 class V	'de novo' posttranslational protein folding	Biological process	-
DLK2	65989	delta-like 2 homolog (Drosophila)	calcium ion binding	Molecular function	-
NR1H4	9971	nuclear receptor subfamily 1, group H, member 4	digestive tract development	Biological process	-
MYRFL	196446	myelin regulatory factor-like	regulation of transcription, DNA-templated	Biological process	-
TERF1	7013	telomeric repeat binding factor (NIMA-interacting) 1	positive regulation of mitotic cell cycle	Biological process	9391075
CPPED1	55313	calcineurin-like phosphoesterase domain containing 1	metal ion binding	Molecular function	-
NPHP3	27031	nephronophthisis 3 (adolescent)	determination of left/right symmetry	Biological process	18371931
COL9A1	1297	collagen, type IX, alpha 1	axon guidance	Biological process	-
PPARA	5465	peroxisome proliferator-activated receptor alpha	wound healing	Biological process	-
PARK7	11315	parkinson protein 7	negative regulation of death-inducing signaling complex assembly	Biological process	21785459
ARF6	382	ADP-ribosylation factor 6	regulation of Rac protein signal transduction	Biological process	10036235
SH3BGRL3	83442	SH3 domain binding glutamate-rich protein like 3	regulation of actin cytoskeleton organization	Biological process	24841563
MSH6	2956	mutS homolog 6	ATP binding	Molecular function	15105434
SDCCAG8	10806	serologically defined colon cancer antigen 8	establishment of cell polarity	Biological process	-
SHH	6469	sonic hedgehog	intein-mediated protein splicing	Biological process	-
ADORA1	134	adenosine A1 receptor	negative regulation of leukocyte migration	Biological process	-
ITK	3702	IL2-inducible T-cell kinase	regulation of cell proliferation	Biological process	-
CHRNB2	1141	cholinergic receptor, nicotinic, beta 2 (neuronal)	acetylcholine receptor activity	Molecular function	8906617
AJUBA	84962	ajuba LIM protein	lamellipodium assembly	Biological process	-
DEDD	9191	death effector domain containing	nucleolus	Cellular component	-
CST3	1471	cystatin C	response to nutrient levels	Biological process	-
PRKAG2	51422	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	sterol biosynthetic process	Biological process	9208914
EGF	1950	epidermal growth factor	neurotrophin TRK receptor signaling pathway	Biological process	-
SRF	6722	serum response factor (c-fos serum response element-binding transcription factor)	stress fiber assembly	Biological process	-
OR4P4	81300	olfactory receptor, family 4, subfamily P, member 4	detection of chemical stimulus involved in sensory perception	Biological process	-
PRKDC	5591	protein kinase, DNA-activated, catalytic polypeptide	somitogenesis	Biological process	-
PPP5C	5536	protein phosphatase 5, catalytic subunit	phosphoprotein phosphatase activity	Molecular function	9383998
GDNF	2668	glial cell derived neurotrophic factor	metanephros development	Biological process	-
MVP	9961	major vault protein	ERBB signaling pathway	Biological process	15133037
ABL1	25	ABL proto-oncogene 1, non-receptor tyrosine kinase	negative regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	-
BAZ1A	11177	bromodomain adjacent to zinc finger domain, 1A	regulation of transcription, DNA-templated	Biological process	10662543
GNA12	2768	guanine nucleotide binding protein (G protein) alpha 12	response to drug	Biological process	-
PCM1	5108	pericentriolar material 1	nuclear membrane	Cellular component	-
RXFP3	51289	relaxin/insulin-like family peptide receptor 3	integral component of plasma membrane	Cellular component	10806363
OR52A1	23538	olfactory receptor, family 52, subfamily A, member 1	G-protein coupled receptor activity	Molecular function	-
DSN1	79980	DSN1, MIS12 kinetochore complex component	protein binding	Molecular function	15502821
SNX16	64089	sorting nexin 16	early endosome membrane	Cellular component	-
CNTNAP1	8506	contactin associated protein 1	neuron projection morphogenesis	Biological process	-
UBE2H	7328	ubiquitin-conjugating enzyme E2H	ligase activity	Molecular function	-
BCL2	596	B-cell CLL/lymphoma 2	regulation of protein homodimerization activity	Biological process	9111042
GRID2IP	392862	glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein	long term synaptic depression	Biological process	-
ADCY8	114	adenylate cyclase 8 (brain)	activation of protein kinase A activity	Biological process	-
HIST2H4A	8370	histone cluster 2, H4a	negative regulation of gene expression, epigenetic	Biological process	-
TAC1	6863	tachykinin, precursor 1	positive regulation of corticosterone secretion	Biological process	-
ATP2A1	487	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	maintenance of mitochondrion location	Biological process	19061639
ZNF668	79759	zinc finger protein 668	nucleus	Cellular component	-
CXCR2	3579	chemokine (C-X-C motif) receptor 2	integral component of plasma membrane	Cellular component	10438939
DNAJC13	23317	DnaJ (Hsp40) homolog, subfamily C, member 13	WASH complex	Cellular component	24643499
MZF1	7593	myeloid zinc finger 1	nucleus	Cellular component	-
GNA12	2768	guanine nucleotide binding protein (G protein) alpha 12	adenylate cyclase-modulating G-protein coupled receptor signaling pathway	Biological process	-
EZH2	2146	enhancer of zeste 2 polycomb repressive complex 2 subunit	cytoplasm	Cellular component	-
PLA2G5	5322	phospholipase A2, group V	platelet activating factor biosynthetic process	Biological process	-
SUOX	6821	sulfite oxidase	small molecule metabolic process	Biological process	-
EIF5A	1984	eukaryotic translation initiation factor 5A	nucleus	Cellular component	12210765
RAD51D	5892	RAD51 paralog D	DNA binding	Molecular function	9570954
CLDN11	5010	claudin 11	basal part of cell	Cellular component	-
CYP2U1	113612	cytochrome P450, family 2, subfamily U, polypeptide 1	omega-hydroxylase P450 pathway	Biological process	-
COL5A3	50509	collagen, type V, alpha 3	skin development	Biological process	10722718
TPM2	7169	tropomyosin 2 (beta)	actin binding	Molecular function	17194691
CLDN5	7122	claudin 5	structural molecule activity	Molecular function	-
EXOC4	60412	exocyst complex component 4	protein binding	Molecular function	18329369
SOX8	30812	SRY (sex determining region Y)-box 8	enteric nervous system development	Biological process	-
TCEAL3	85012	transcription elongation factor A (SII)-like 3	transcription, DNA-templated	Biological process	-
PTPN11	5781	protein tyrosine phosphatase, non-receptor type 11	platelet-derived growth factor receptor signaling pathway	Biological process	-
CCNT1	904	cyclin T1	viral process	Biological process	-
ARF4	378	ADP-ribosylation factor 4	response to axon injury	Biological process	-
ANGPT2	285	angiopoietin 2	negative regulation of angiogenesis	Biological process	-
TMOD4	29765	tropomodulin 4 (muscle)	muscle contraction	Biological process	10662549
CYTH2	9266	cytohesin 2	lipid binding	Molecular function	-
HDGF	3068	hepatoma-derived growth factor	heparin binding	Molecular function	-
FGF22	27006	fibroblast growth factor 22	cell surface	Cellular component	-
MC1R	4157	melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)	positive regulation of protein kinase B signaling	Biological process	18292087
COPS2	9318	COP9 signalosome subunit 2	signal transducer activity	Molecular function	9535219
TGFB1	7040	transforming growth factor, beta 1	positive regulation of bone mineralization	Biological process	17401695
GALNT6	11226	polypeptide N-acetylgalactosaminyltransferase 6	integral component of membrane	Cellular component	-
PCBP2	5094	poly(rC) binding protein 2	cytosol	Cellular component	-
GAD1	2571	glutamate decarboxylase 1 (brain, 67kDa)	protein heterodimerization activity	Molecular function	-
SPCS3	60559	signal peptidase complex subunit 3 homolog (S. cerevisiae)	regulation of insulin secretion	Biological process	-
PPM1A	5494	protein phosphatase, Mg2+/Mn2+ dependent, 1A	protein dephosphorylation	Biological process	18930133
TAC1	6863	tachykinin, precursor 1	cell-cell signaling	Biological process	1708336
MYOD1	4654	myogenic differentiation 1	myofibril	Cellular component	-
HES5	388585	hes family bHLH transcription factor 5	negative regulation of inner ear receptor cell differentiation	Biological process	-
EZH2	2146	enhancer of zeste 2 polycomb repressive complex 2 subunit	regulation of cell proliferation	Biological process	-
MACF1	23499	microtubule-actin crosslinking factor 1	actin binding	Molecular function	10559237
TTK	7272	TTK protein kinase	spindle organization	Biological process	10366450
DMP1	1758	dentin matrix acidic phosphoprotein 1	proteinaceous extracellular matrix	Cellular component	-
SNTG1	54212	syntrophin, gamma 1	nucleus	Cellular component	-
WDR5	11091	WD repeat domain 5	nucleus	Cellular component	17500065
CCR3	1232	chemokine (C-C motif) receptor 3	chemokine-mediated signaling pathway	Biological process	10415069
DPRX	503834	divergent-paired related homeobox	sequence-specific DNA binding	Molecular function	-
CYP4F2	8529	cytochrome P450, family 4, subfamily F, polypeptide 2	very long-chain fatty acid metabolic process	Biological process	18433732
TNFRSF11A	8792	tumor necrosis factor receptor superfamily, member 11a, NFKB activator	response to lipopolysaccharide	Biological process	19940926
MYZAP	100820829	myocardial zonula adherens protein	cortical actin cytoskeleton	Cellular component	-
EPHB2	2048	EPH receptor B2	central nervous system projection neuron axonogenesis	Biological process	-
CDH26	60437	cadherin 26	plasma membrane	Cellular component	-
FUBP3	8939	far upstream element (FUSE) binding protein 3	protein binding	Molecular function	16713569
GPBP1L1	60313	GC-rich promoter binding protein 1-like 1	transcription, DNA-templated	Biological process	-
DCSTAMP	81501	dendrocyte expressed seven transmembrane protein	endoplasmic reticulum-Golgi intermediate compartment membrane	Cellular component	-
USP4	7375	ubiquitin specific peptidase 4 (proto-oncogene)	nucleus	Cellular component	16339847
ESR1	2099	estrogen receptor 1	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	12047722
MYF6	4618	myogenic factor 6 (herculin)	positive regulation of myoblast fusion	Biological process	-
CYP27B1	1594	cytochrome P450, family 27, subfamily B, polypeptide 1	calcitriol biosynthetic process from calciol	Biological process	15795327
CABYR	26256	calcium binding tyrosine-(Y)-phosphorylation regulated	nucleus	Cellular component	-
TERT	7015	telomerase reverse transcriptase	mitochondrial nucleoid	Cellular component	21937513
DMTN	2039	dematin actin binding protein	cortical cytoskeleton	Cellular component	-
SSTR3	6753	somatostatin receptor 3	negative regulation of cell proliferation	Biological process	8961277
CBLB	868	Cbl proto-oncogene B, E3 ubiquitin protein ligase	calcium ion binding	Molecular function	-
TDG	6996	thymine-DNA glycosylase	transcription from RNA polymerase II promoter	Biological process	-
LIPF	8513	lipase, gastric	cellular_component	Cellular component	-
RASAL2	9462	RAS protein activator like 2	signal transduction	Biological process	-
RAI14	26064	retinoic acid induced 14	actin cytoskeleton	Cellular component	-
LIMS2	55679	LIM and senescent cell antigen-like domains 2	single organismal cell-cell adhesion	Biological process	-
EMX2	2018	empty spiracles homeobox 2	anterior/posterior pattern specification	Biological process	-
FUT8	2530	fucosyltransferase 8 (alpha (1,6) fucosyltransferase)	cellular protein metabolic process	Biological process	-
ACTR5	79913	ARP5 actin-related protein 5 homolog (yeast)	double-strand break repair	Biological process	19014934
SLC16A1	6566	solute carrier family 16 (monocarboxylate transporter), member 1	mevalonate transport	Biological process	1429658
DSCR4	10281	Down syndrome critical region 4	cellular_component	Cellular component	-
GLRA4	441509	glycine receptor, alpha 4	extracellular ligand-gated ion channel activity	Molecular function	-
GSPT1	2935	G1 to S phase transition 1	translational termination	Biological process	15326224
FGD3	89846	FYVE, RhoGEF and PH domain containing 3	small GTPase mediated signal transduction	Biological process	-
PNKD	25953	paroxysmal nonkinesigenic dyskinesia	regulation of dopamine metabolic process	Biological process	-
KCNH2	3757	potassium channel, voltage gated eag related subfamily H, member 2	positive regulation of potassium ion transmembrane transport	Biological process	7736582
OMP	4975	olfactory marker protein	signal transducer activity	Molecular function	-
OR6B2	389090	olfactory receptor, family 6, subfamily B, member 2	odorant binding	Molecular function	-
SCYL3	57147	SCY1-like 3 (S. cerevisiae)	cell migration	Biological process	12651155
CRYAB	1410	crystallin, alpha B	muscle organ development	Biological process	-
OR10G3	26533	olfactory receptor, family 10, subfamily G, member 3	integral component of membrane	Cellular component	-
HBG1	3047	hemoglobin, gamma A	iron ion binding	Molecular function	-
OR7A5	26659	olfactory receptor, family 7, subfamily A, member 5	G-protein coupled receptor activity	Molecular function	-
SLX1A	548593	SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)	protein binding	Molecular function	19595721
NCKAP1	10787	NCK-associated protein 1	focal adhesion	Cellular component	21423176
SLC22A16	85413	solute carrier family 22 (organic cation/carnitine transporter), member 16	organic cation transmembrane transporter activity	Molecular function	15963465
TOP1	7150	topoisomerase (DNA) I	circadian regulation of gene expression	Biological process	22904072
CAMK1D	57118	calcium/calmodulin-dependent protein kinase ID	ATP binding	Molecular function	-
UBC	7316	ubiquitin C	mitotic cell cycle	Biological process	-
MRAS	22808	muscle RAS oncogene homolog	actin cytoskeleton organization	Biological process	9395237
OSBPL8	114882	oxysterol binding protein-like 8	protein localization to nuclear pore	Biological process	-
MYO1C	4641	myosin IC	stereocilium membrane	Cellular component	-
TAOK3	51347	TAO kinase 3	cellular response to DNA damage stimulus	Biological process	17396146
EEA1	8411	early endosome antigen 1	1-phosphatidylinositol binding	Molecular function	11256955
TRIM8	81603	tripartite motif containing 8	cytokine-mediated signaling pathway	Biological process	-
KLK9	284366	kallikrein-related peptidase 9	extracellular region	Cellular component	-
DLG4	1742	discs, large homolog 4 (Drosophila)	negative regulation of receptor internalization	Biological process	-
TSHB	7252	thyroid stimulating hormone, beta	peptide hormone processing	Biological process	-
COL4A3BP	10087	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein	sphingolipid biosynthetic process	Biological process	-
RYR2	6262	ryanodine receptor 2 (cardiac)	cytosol	Cellular component	-
TCF3	6929	transcription factor 3	positive regulation of muscle cell differentiation	Biological process	-
ARCN1	372	archain 1	poly(A) RNA binding	Molecular function	22658674
KCNJ4	3761	potassium channel, inwardly rectifying subfamily J, member 4	plasma membrane	Cellular component	-
PARP1	142	poly (ADP-ribose) polymerase 1	poly(A) RNA binding	Molecular function	22658674
VN1R2	317701	vomeronasal 1 receptor 2	response to pheromone	Biological process	-
ERBB4	2066	erb-b2 receptor tyrosine kinase 4	protein autophosphorylation	Biological process	18334220
P4HB	5034	prolyl 4-hydroxylase, beta polypeptide	cell redox homeostasis	Biological process	-
SORT1	6272	sortilin 1	response to insulin	Biological process	15992544
MDFI	4188	MyoD family inhibitor	embryonic skeletal system morphogenesis	Biological process	-
STX18	53407	syntaxin 18	Golgi membrane	Cellular component	-
COX7A2L	9167	cytochrome c oxidase subunit VIIa polypeptide 2 like	gene expression	Biological process	-
SLC12A1	6557	solute carrier family 12 (sodium/potassium/chloride transporter), member 1	apical plasma membrane	Cellular component	-
SMARCD1	6602	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	nervous system development	Biological process	-
BPGM	669	2,3-bisphosphoglycerate mutase	dephosphorylation	Biological process	-
RBM14	10432	RNA binding motif protein 14	RNA polymerase II transcription cofactor activity	Molecular function	11443112
GNB2	2783	guanine nucleotide binding protein (G protein), beta polypeptide 2	plasma membrane	Cellular component	-
SPO11	23626	SPO11 meiotic protein covalently bound to DSB	ovarian follicle development	Biological process	-
GALNT1	2589	polypeptide N-acetylgalactosaminyltransferase 1	protein O-linked glycosylation via serine	Biological process	9295285
SLC16A5	9121	solute carrier family 16 (monocarboxylate transporter), member 5	integral component of plasma membrane	Cellular component	9425115
CCL21	6366	chemokine (C-C motif) ligand 21	chemokine receptor binding	Molecular function	23341447
GPR42	2866	G protein-coupled receptor 42 (gene/pseudogene)	G-protein coupled receptor activity	Molecular function	19630535
PPCDC	60490	phosphopantothenoylcysteine decarboxylase	phosphopantothenoylcysteine decarboxylase activity	Molecular function	-
MYOC	4653	myocilin, trabecular meshwork inducible glucocorticoid response	node of Ranvier	Cellular component	-
ARV1	64801	ARV1 homolog (S. cerevisiae)	sphingolipid metabolic process	Biological process	-
MX2	4600	MX dynamin-like GTPase 2	nuclear pore	Cellular component	15184662
ADAM18	8749	ADAM metallopeptidase domain 18	integral component of membrane	Cellular component	-
CX3CL1	6376	chemokine (C-X3-C motif) ligand 1	positive regulation of transforming growth factor beta1 production	Biological process	-
MS4A2	2206	membrane-spanning 4-domains, subfamily A, member 2	activation of phospholipase C activity	Biological process	-
CSF1R	1436	colony stimulating factor 1 receptor	positive regulation of chemokine secretion	Biological process	20829061
ENO4	387712	enolase family member 4	glycolytic process	Biological process	-
MDN1	23195	MDN1, midasin homolog (yeast)	cytoplasm	Cellular component	-
HSD17B4	3295	hydroxysteroid (17-beta) dehydrogenase 4	Sertoli cell development	Biological process	-
POLR3A	11128	polymerase (RNA) III (DNA directed) polypeptide A, 155kDa	gene expression	Biological process	-
PPARD	5467	peroxisome proliferator-activated receptor delta	negative regulation of smooth muscle cell proliferation	Biological process	-
DHX58	79132	DEXH (Asp-Glu-X-His) box polypeptide 58	viral process	Biological process	-
ZNF662	389114	zinc finger protein 662	transcription, DNA-templated	Biological process	-
GHSR	2693	growth hormone secretagogue receptor	cellular response to insulin stimulus	Biological process	-
RPL12	6136	ribosomal protein L12	translational termination	Biological process	-
EIF4A1	1973	eukaryotic translation initiation factor 4A1	double-stranded RNA binding	Molecular function	21266579
VIPAS39	63894	VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog	protein binding	Molecular function	16189514
NDUFB7	4713	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa	respiratory electron transport chain	Biological process	-
MARCO	8685	macrophage receptor with collagenous structure	cell surface receptor signaling pathway	Biological process	9468508
SGK1	6446	serum/glucocorticoid regulated kinase 1	protein serine/threonine/tyrosine kinase activity	Molecular function	22797923
TCEANC2	127428	transcription elongation factor A (SII) N-terminal and central domain containing 2	nucleus	Cellular component	-
IRF7	3665	interferon regulatory factor 7	protein binding	Molecular function	11943871
UTY	7404	ubiquitously transcribed tetratricopeptide repeat containing, Y-linked	histone demethylase activity (H3-K27 specific)	Molecular function	-
ABHD14A	25864	abhydrolase domain containing 14A	cytoplasm	Cellular component	-
FTCD	10841	formimidoyltransferase cyclodeaminase	cytoplasm	Cellular component	10029623
GCG	2641	glucagon	response to starvation	Biological process	-
MDH1	4190	malate dehydrogenase 1, NAD (soluble)	NAD binding	Molecular function	-
SMARCE1	6605	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	ATP-dependent chromatin remodeling	Biological process	16217013
RAD50	10111	RAD50 homolog (S. cerevisiae)	ATP binding	Molecular function	-
RBBP4	5928	retinoblastoma binding protein 4	CENP-A containing nucleosome assembly	Biological process	-
SLC39A5	283375	solute carrier family 39 (zinc transporter), member 5	neural precursor cell proliferation	Biological process	-
NFATC1	4772	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
HYAL2	8692	hyaluronoglucosaminidase 2	plasma membrane	Cellular component	-
UGT8	7368	UDP glycosyltransferase 8	cytoskeleton organization	Biological process	-
HTRA4	203100	HtrA serine peptidase 4	negative regulation of transforming growth factor beta receptor signaling pathway	Biological process	-
MAP3K15	389840	mitogen-activated protein kinase kinase kinase 15	ATP binding	Molecular function	-
KATNB1	10300	katanin p80 (WD repeat containing) subunit B 1	cell division	Biological process	-
FOXA2	3170	forkhead box A2	lung epithelial cell differentiation	Biological process	-
GPI	2821	glucose-6-phosphate isomerase	learning or memory	Biological process	-
NCOA3	8202	nuclear receptor coactivator 3	cellular response to hormone stimulus	Biological process	-
HOXA1	3198	homeobox A1	central nervous system neuron differentiation	Biological process	-
AXL	558	AXL receptor tyrosine kinase	negative regulation of lymphocyte activation	Biological process	-
SLC12A9	56996	solute carrier family 12, member 9	integral component of membrane	Cellular component	-
TIMM44	10469	translocase of inner mitochondrial membrane 44 homolog (yeast)	cellular protein metabolic process	Biological process	-
CNKSR2	22866	connector enhancer of kinase suppressor of Ras 2	extracellular exosome	Cellular component	19056867
GSTO1	9446	glutathione S-transferase omega 1	cellular response to arsenic-containing substance	Biological process	11511179
RIT1	6016	Ras-like without CAAX 1	signal transduction	Biological process	8918462
FOXC1	2296	forkhead box C1	cytoplasm	Cellular component	-
NPHP4	261734	nephronophthisis 4	ribbon synapse	Cellular component	-
CSTB	1476	cystatin B (stefin B)	extracellular exosome	Cellular component	19056867
RUVBL2	10856	RuvB-like AAA ATPase 2	DNA repair	Biological process	-
RABIF	5877	RAB interacting factor	protein transport	Biological process	-
FNTA	2339	farnesyltransferase, CAAX box, alpha	protein farnesylation	Biological process	16893176
ITGAD	3681	integrin, alpha D	extracellular matrix organization	Biological process	-
VSIG4	11326	V-set and immunoglobulin domain containing 4	protein binding	Molecular function	16530040
STS	412	steroid sulfatase (microsomal), isozyme S	integral component of membrane	Cellular component	-
DNM1L	10059	dynamin 1-like	intracellular membrane-bounded organelle	Cellular component	-
PIK3CA	5290	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	phospholipid metabolic process	Biological process	-
FGD2	221472	FYVE, RhoGEF and PH domain containing 2	cytoplasm	Cellular component	-
SPR	6697	sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)	aldo-keto reductase (NADP) activity	Molecular function	1883349
FZD8	8325	frizzled class receptor 8	integral component of membrane	Cellular component	11295046
COL5A2	1290	collagen, type V, alpha 2	skin development	Biological process	-
GAS2L1	10634	growth arrest-specific 2 like 1	microtubule	Cellular component	12584248
OR10D4P	390266	olfactory receptor, family 10, subfamily D, member 4 pseudogene	G-protein coupled receptor signaling pathway	Biological process	-
ZNF594	84622	zinc finger protein 594	nucleus	Cellular component	-
GLRB	2743	glycine receptor, beta	extracellular-glycine-gated ion channel activity	Molecular function	11929858
HILPDA	29923	hypoxia inducible lipid droplet-associated	lipid particle	Cellular component	20624928
CCR10	2826	chemokine (C-C motif) receptor 10	G-protein coupled receptor activity	Molecular function	7851889
ARNT	405	aryl hydrocarbon receptor nuclear translocator	RNA polymerase II transcription factor complex	Cellular component	7539918
TIMP2	7077	TIMP metallopeptidase inhibitor 2	extracellular matrix organization	Biological process	-
STX4	6810	syntaxin 4	vacuole	Cellular component	16339081
CDKN2A	1029	cyclin-dependent kinase inhibitor 2A	activation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	12082630
NRG3	10718	neuregulin 3	receptor binding	Molecular function	-
NAA15	80155	N(alpha)-acetyltransferase 15, NatA auxiliary subunit	protein binding	Molecular function	12145306
RIPK4	54101	receptor-interacting serine-threonine kinase 4	morphogenesis of an epithelium	Biological process	22197488
ITGAM	3684	integrin, alpha M (complement component 3 receptor 3 subunit)	extracellular exosome	Cellular component	23376485
CD36	948	CD36 molecule (thrombospondin receptor)	negative regulation of transcription factor import into nucleus	Biological process	-
IL5	3567	interleukin 5	extracellular region	Cellular component	-
PDIA3	2923	protein disulfide isomerase family A, member 3	cell surface	Cellular component	19995400
GBA	2629	glucosidase, beta, acid	glycosphingolipid metabolic process	Biological process	-
OR2L8	391190	olfactory receptor, family 2, subfamily L, member 8 (gene/pseudogene)	G-protein coupled receptor signaling pathway	Biological process	-
MRPL37	51253	mitochondrial ribosomal protein L37	structural constituent of ribosome	Molecular function	11543634
DPP4	1803	dipeptidyl-peptidase 4	integral component of membrane	Cellular component	-
GNG11	2791	guanine nucleotide binding protein (G protein), gamma 11	G-protein coupled receptor signaling pathway	Biological process	-
COASY	80347	CoA synthase	protein binding	Molecular function	22982864
PRLHR	2834	prolactin releasing hormone receptor	G-protein coupled receptor signaling pathway	Biological process	8666380
IFNG	3458	interferon, gamma	defense response to bacterium	Biological process	-
IQCB1	9657	IQ motif containing B1	maintenance of organ identity	Biological process	15723066
CD37	951	CD37 molecule	membrane	Cellular component	19946888
OR6C70	390327	olfactory receptor, family 6, subfamily C, member 70	plasma membrane	Cellular component	-
OLIG2	10215	oligodendrocyte lineage transcription factor 2	positive regulation of oligodendrocyte differentiation	Biological process	-
CELF3	11189	CUGBP, Elav-like family member 3	sperm motility	Biological process	-
RAB3B	5865	RAB3B, member RAS oncogene family	GDP binding	Molecular function	22321395
CCR7	1236	chemokine (C-C motif) receptor 7	immune response	Biological process	-
CYC1	1537	cytochrome c-1	heme binding	Molecular function	-
COG2	22796	component of oligomeric golgi complex 2	intra-Golgi vesicle-mediated transport	Biological process	7962052
KAT5	10524	K(lysine) acetyltransferase 5	cytosol	Cellular component	-
CD55	1604	CD55 molecule, decay accelerating factor for complement (Cromer blood group)	plasma membrane	Cellular component	-
MEFV	4210	Mediterranean fever	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	Biological process	-
TK2	7084	thymidine kinase 2, mitochondrial	deoxycytidine kinase activity	Molecular function	-
AMN	81693	amnion associated transmembrane protein	apical plasma membrane	Cellular component	14576052
CYC1	1537	cytochrome c-1	metal ion binding	Molecular function	-
HMGB2	3148	high mobility group box 2	chemoattractant activity	Molecular function	19811285
RP1L1	94137	retinitis pigmentosa 1-like 1	extracellular exosome	Cellular component	23376485
GABARAPL1	23710	GABA(A) receptor-associated protein like 1	autophagosome membrane	Cellular component	-
NUDC	10726	nudC nuclear distribution protein	cell division	Biological process	-
SYTL2	54843	synaptotagmin-like 2	extrinsic component of plasma membrane	Cellular component	-
GZF1	64412	GDNF-inducible zinc finger protein 1	cytoplasm	Cellular component	-
DDX47	51202	DEAD (Asp-Glu-Ala-Asp) box polypeptide 47	ATP-dependent RNA helicase activity	Molecular function	-
NUDT16	131870	nudix (nucleoside diphosphate linked moiety X)-type motif 16	inosine-diphosphatase activity	Molecular function	-
ATM	472	ATM serine/threonine kinase	peptidyl-serine phosphorylation	Biological process	9733515
VPS36	51028	vacuolar protein sorting 36 homolog (S. cerevisiae)	late endosome membrane	Cellular component	17010938
NUP160	23279	nucleoporin 160kDa	cytokine-mediated signaling pathway	Biological process	-
RIC8B	55188	RIC8 guanine nucleotide exchange factor B	cell cortex	Cellular component	-
PSMF1	9491	proteasome (prosome, macropain) inhibitor subunit 1 (PI31)	negative regulation of proteasomal protein catabolic process	Biological process	10764772
PLK4	10733	polo-like kinase 4	centrosome	Cellular component	21399614
HLA-DRA	3122	major histocompatibility complex, class II, DR alpha	T cell costimulation	Biological process	-
HYAL2	8692	hyaluronoglucosaminidase 2	cellular response to UV-B	Biological process	21699545
PTPN11	5781	protein tyrosine phosphatase, non-receptor type 11	megakaryocyte development	Biological process	-
COL5A3	50509	collagen, type V, alpha 3	collagen fibril organization	Biological process	10722718
DTL	51514	denticleless E3 ubiquitin protein ligase homolog (Drosophila)	protein polyubiquitination	Biological process	17085480
DPYS	1807	dihydropyrimidinase	small molecule metabolic process	Biological process	-
NOS2	4843	nitric oxide synthase 2, inducible	defense response to Gram-negative bacterium	Biological process	18390757
PDLIM3	27295	PDZ and LIM domain 3	actin cytoskeleton	Cellular component	-
ATG5	9474	autophagy related 5	vasodilation	Biological process	-
STAT3	6774	signal transducer and activator of transcription 3 (acute-phase response factor)	acute-phase response	Biological process	-
RNPC3	55599	RNA-binding region (RNP1, RRM) containing 3	nucleotide binding	Molecular function	-
SOD1	6647	superoxide dismutase 1, soluble	superoxide dismutase activity	Molecular function	-
PRMT7	54496	protein arginine methyltransferase 7	regulation of gene expression by genetic imprinting	Biological process	-
ST6GAL2	84620	ST6 beta-galactosamide alpha-2,6-sialyltranferase 2	Golgi membrane	Cellular component	-
MAP1S	55201	microtubule-associated protein 1S	nucleolus	Cellular component	-
TBC1D17	79735	TBC1 domain family, member 17	cytosol	Cellular component	17562788
ITCH	83737	itchy E3 ubiquitin protein ligase	protein K29-linked ubiquitination	Biological process	17028573
RC3H1	149041	ring finger and CCCH-type domains 1	lymph node development	Biological process	-
CCDC53	51019	coiled-coil domain containing 53	intracellular membrane-bounded organelle	Cellular component	-
STAT5A	6776	signal transducer and activator of transcription 5A	valine metabolic process	Biological process	-
TMEM8C	389827	transmembrane protein 8C	plasma membrane	Cellular component	-
SPHK1	8877	sphingosine kinase 1	sphingosine metabolic process	Biological process	20577214
GABRA3	2556	gamma-aminobutyric acid (GABA) A receptor, alpha 3	chloride channel complex	Cellular component	-
ARAP3	64411	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	negative regulation of cell migration	Biological process	-
AURKB	9212	aurora kinase B	condensed nuclear chromosome, centromeric region	Cellular component	18195732
NDOR1	27158	NADPH dependent diflavin oxidoreductase 1	small molecule metabolic process	Biological process	-
SLC6A4	6532	solute carrier family 6 (neurotransmitter transporter), member 4	response to hypoxia	Biological process	-
SAG	6295	S-antigen; retina and pineal gland (arrestin)	photoreceptor inner segment	Cellular component	-
RNF4	6047	ring finger protein 4	transcription, DNA-templated	Biological process	-
DESI2	51029	desumoylating isopeptidase 2	proteolysis	Biological process	-
AXIN2	8313	axin 2	regulation of transcription, DNA-templated	Biological process	-
CXCL1	2919	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	cell chemotaxis	Biological process	10820279
DENND1A	57706	DENN/MADD domain containing 1A	presynaptic membrane	Cellular component	-
AMACR	23600	alpha-methylacyl-CoA racemase	alpha-methylacyl-CoA racemase activity	Molecular function	10655068
CYP21A2	1589	cytochrome P450, family 21, subfamily A, polypeptide 2	oxidation-reduction process	Biological process	-
ZNF148	7707	zinc finger protein 148	transcription from RNA polymerase II promoter	Biological process	9685330
TUBB3	10381	tubulin, beta 3 class III	peptide binding	Molecular function	-
NR5A1	2516	nuclear receptor subfamily 5, group A, member 1	intracellular receptor signaling pathway	Biological process	8205615
CDK5RAP3	80279	CDK5 regulatory subunit associated protein 3	negative regulation of cellular protein catabolic process	Biological process	16173922
PSMD13	5719	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	proteasome regulatory particle	Cellular component	-
SPO11	23626	SPO11 meiotic protein covalently bound to DSB	spermatid development	Biological process	-
TMEM39A	55254	transmembrane protein 39A	positive regulation of defense response to virus by host	Biological process	22020285
CNOT2	4848	CCR4-NOT transcription complex, subunit 2	positive regulation of cytoplasmic mRNA processing body assembly	Biological process	21299754
OR4K15	81127	olfactory receptor, family 4, subfamily K, member 15	olfactory receptor activity	Molecular function	-
RASIP1	54922	Ras interacting protein 1	signal transduction	Biological process	-
TMEM64	169200	transmembrane protein 64	cytosolic calcium ion homeostasis	Biological process	-
NMNAT1	64802	nicotinamide nucleotide adenylyltransferase 1	nicotinamide-nucleotide adenylyltransferase activity	Molecular function	-
HLA-DMA	3108	major histocompatibility complex, class II, DM alpha	inner ear development	Biological process	-
PIK3R1	5295	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	phosphatidylinositol 3-kinase complex, class IA	Cellular component	-
RET	5979	ret proto-oncogene	protein binding	Molecular function	11536047
RYR1	6261	ryanodine receptor 1 (skeletal)	I band	Cellular component	11206130
TCEAL6	158931	transcription elongation factor A (SII)-like 6	nucleus	Cellular component	-
CACNA2D1	781	calcium channel, voltage-dependent, alpha 2/delta subunit 1	regulation of calcium ion transport	Biological process	1309651
TBX10	347853	T-box 10	nucleus	Cellular component	-
NOD2	64127	nucleotide-binding oligomerization domain containing 2	positive regulation of interleukin-1 beta production	Biological process	21040358
CRY2	1408	cryptochrome circadian clock 2	negative regulation of transcription from RNA polymerase II promoter	Biological process	12397359
NOD2	64127	nucleotide-binding oligomerization domain containing 2	toll-like receptor TLR1:TLR2 signaling pathway	Biological process	-
GNA13	10672	guanine nucleotide binding protein (G protein), alpha 13	Rho protein signal transduction	Biological process	-
DNAJC7	7266	DnaJ (Hsp40) homolog, subfamily C, member 7	cellular response to heat	Biological process	-
INA	9118	internexin neuronal intermediate filament protein, alpha	structural constituent of cytoskeleton	Molecular function	7769995
UBE2B	7320	ubiquitin-conjugating enzyme E2B	ubiquitin protein ligase activity	Molecular function	-
HES3	390992	hes family bHLH transcription factor 3	midbrain-hindbrain boundary morphogenesis	Biological process	-
MIA2	117153	melanoma inhibitory activity 2	cholesterol homeostasis	Biological process	-
SIN3B	23309	SIN3 transcription regulator family member B	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
DCTN1	1639	dynactin 1	microtubule	Cellular component	21525035
KLF17	128209	Kruppel-like factor 17	transcription regulatory region DNA binding	Molecular function	-
AQP1	358	aquaporin 1 (Colton blood group)	cellular response to retinoic acid	Biological process	12051745
SOHLH2	54937	spermatogenesis and oogenesis specific basic helix-loop-helix 2	oogenesis	Biological process	-
YWHAH	7533	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	Biological process	-
SLC17A9	63910	solute carrier family 17 (vesicular nucleotide transporter), member 9	transmembrane transporter activity	Molecular function	-
DBH	1621	dopamine beta-hydroxylase (dopamine beta-monooxygenase)	secretory granule lumen	Cellular component	-
FKBP4	2288	FK506 binding protein 4, 59kDa	poly(A) RNA binding	Molecular function	22658674
RIPK1	8737	receptor (TNFRSF)-interacting serine-threonine kinase 1	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	Biological process	-
MDM4	4194	MDM4, p53 regulator	cellular response to hypoxia	Biological process	20810912
RNF38	152006	ring finger protein 38	protein ubiquitination	Biological process	-
PARK2	5071	parkin RBR E3 ubiquitin protein ligase	cellular protein catabolic process	Biological process	21376232
TREH	11181	trehalase (brush-border membrane glycoprotein)	plasma membrane	Cellular component	9427547
KCNC2	3747	potassium channel, voltage gated Shaw related subfamily C, member 2	synaptic transmission	Biological process	-
PLSCR1	5359	phospholipid scramblase 1	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	16091359
UBE2M	9040	ubiquitin-conjugating enzyme E2M	ubiquitin-protein transferase activity	Molecular function	9694792
RPS5	6193	ribosomal protein S5	cytosol	Cellular component	-
LMLN	89782	leishmanolysin-like (metallopeptidase M8 family)	focal adhesion	Cellular component	-
ABHD8	79575	abhydrolase domain containing 8	extracellular exosome	Cellular component	18570454
STK3	6788	serine/threonine kinase 3	positive regulation of protein binding	Biological process	22292086
NUP43	348995	nucleoporin 43kDa	carbohydrate metabolic process	Biological process	-
KLF4	9314	Kruppel-like factor 4 (gut)	mesodermal cell fate determination	Biological process	8940147
ITGA2	3673	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	cellular response to hormone stimulus	Biological process	-
ENSA	2029	endosulfine alpha	protein phosphatase inhibitor activity	Molecular function	-
ATP9A	10079	ATPase, class II, type 9A	early endosome	Cellular component	21914794
PRG3	10394	proteoglycan 3	immune response	Biological process	-
KDM5B	10765	lysine (K)-specific demethylase 5B	transcription corepressor activity	Molecular function	12657635
OR1S2	219958	olfactory receptor, family 1, subfamily S, member 2	olfactory receptor activity	Molecular function	-
BEX2	84707	brain expressed X-linked 2	nucleus	Cellular component	-
CDK1	983	cyclin-dependent kinase 1	innate immune response	Biological process	-
SPTBN1	6711	spectrin, beta, non-erythrocytic 1	GTPase binding	Molecular function	24337748
CRBN	51185	cereblon	negative regulation of protein homooligomerization	Biological process	-
VIPAS39	63894	VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog	HOPS complex	Cellular component	19109425
TAPBP	6892	TAP binding protein (tapasin)	antigen processing and presentation of endogenous peptide antigen via MHC class I	Biological process	-
ADAMTS13	11093	ADAM metallopeptidase with thrombospondin type 1 motif, 13	metalloendopeptidase activity	Molecular function	-
SERPING1	710	serpin peptidase inhibitor, clade G (C1 inhibitor), member 1	aging	Biological process	-
CASP3	836	caspase 3, apoptosis-related cysteine peptidase	cellular response to DNA damage stimulus	Biological process	-
ABCA1	19	ATP-binding cassette, sub-family A (ABC1), member 1	transmembrane transport	Biological process	-
PLEKHA4	57664	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4	1-phosphatidylinositol binding	Molecular function	11001876
GHRHR	2692	growth hormone releasing hormone receptor	growth factor binding	Molecular function	7680413
SOST	50964	sclerostin	negative regulation of ossification	Biological process	11181578
FUT10	84750	fucosyltransferase 10 (alpha (1,3) fucosyltransferase)	fertilization	Biological process	11698403
UBE2L6	9246	ubiquitin-conjugating enzyme E2L 6	negative regulation of type I interferon production	Biological process	-
FBXL5	26234	F-box and leucine-rich repeat protein 5	ubiquitin ligase complex	Cellular component	10531035
OVOL2	58495	ovo-like zinc finger 2	neural fold formation	Biological process	-
DDIT3	1649	DNA-damage-inducible transcript 3	protein homodimerization activity	Molecular function	-
OR10G4	390264	olfactory receptor, family 10, subfamily G, member 4	integral component of membrane	Cellular component	-
ZNF473	25888	zinc finger protein 473	mRNA 3'-end processing	Biological process	-
MMS22L	253714	MMS22-like, DNA repair protein	double-strand break repair via homologous recombination	Biological process	21055983
WNT5A	7474	wingless-type MMTV integration site family, member 5A	positive regulation of protein catabolic process	Biological process	12952940
NKX2-5	1482	NK2 homeobox 5	negative regulation of myotube differentiation	Biological process	15653675
SFN	2810	stratifin	extracellular exosome	Cellular component	19056867
TTC1	7265	tetratricopeptide repeat domain 1	protein folding	Biological process	8836031
GABRR2	2570	gamma-aminobutyric acid (GABA) A receptor, rho 2	signal transduction	Biological process	1315307
ZXDC	79364	ZXD family zinc finger C	sequence-specific DNA binding transcription factor activity	Molecular function	17493635
NCOA3	8202	nuclear receptor coactivator 3	positive regulation of transcription, DNA-templated	Biological process	15572661
ASCL1	429	achaete-scute family bHLH transcription factor 1	chromatin binding	Molecular function	-
SHH	6469	sonic hedgehog	positive regulation of kidney smooth muscle cell differentiation	Biological process	-
CENPV	201161	centromere protein V	pericentric heterochromatin assembly	Biological process	18772885
KLF2	10365	Kruppel-like factor 2	Type I pneumocyte differentiation	Biological process	-
TRIM28	10155	tripartite motif containing 28	negative regulation of viral release from host cell	Biological process	18248090
FGD2	221472	FYVE, RhoGEF and PH domain containing 2	guanyl-nucleotide exchange factor activity	Molecular function	-
RSPH4A	345895	radial spoke head 4 homolog A (Chlamydomonas)	nucleoplasm	Cellular component	-
BACE1	23621	beta-site APP-cleaving enzyme 1	peptidase activity	Molecular function	8562317
SALL1	6299	spalt-like transcription factor 1	sequence-specific DNA binding transcription factor activity	Molecular function	9425907
PPP4R2	151987	protein phosphatase 4, regulatory subunit 2	nucleoplasm	Cellular component	-
AHR	196	aryl hydrocarbon receptor	ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity	Molecular function	10395741
ERCC2	2068	excision repair cross-complementation group 2	extracellular matrix organization	Biological process	-
PURB	5814	purine-rich element binding protein B	transcription, DNA-templated	Biological process	-
IRF2	3660	interferon regulatory factor 2	interferon-gamma-mediated signaling pathway	Biological process	-
RARA	5914	retinoic acid receptor, alpha	signal transduction	Biological process	2825025
FGD5	152273	FYVE, RhoGEF and PH domain containing 5	early endosome	Cellular component	-
ARID5B	84159	AT rich interactive domain 5B (MRF1-like)	palate development	Biological process	-
PSEN1	5663	presenilin 1	regulation of protein binding	Biological process	-
PAPOLA	10914	poly(A) polymerase alpha	ATP binding	Molecular function	-
MAP4K1	11184	mitogen-activated protein kinase kinase kinase kinase 1	peptidyl-serine phosphorylation	Biological process	11053428
SLC6A8	6535	solute carrier family 6 (neurotransmitter transporter), member 8	creatine transport	Biological process	8661037
POP1	10940	processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)	tRNA catabolic process	Biological process	8918471
TRIO	7204	trio Rho guanine nucleotide exchange factor	cytosol	Cellular component	-
INHA	3623	inhibin, alpha	skeletal system development	Biological process	10865214
PIEZO1	9780	piezo-type mechanosensitive ion channel component 1	mechanically-gated ion channel activity	Molecular function	-
PYCARD	29108	PYD and CARD domain containing	tumor necrosis factor-mediated signaling pathway	Biological process	12656673
SHB	6461	Src homology 2 domain containing adaptor protein B	SH3/SH2 adaptor activity	Molecular function	8302579
HSP90AA1	3320	heat shock protein 90kDa alpha (cytosolic), class A member 1	dATP binding	Molecular function	-
AGRN	375790	agrin	heparan sulfate proteoglycan binding	Molecular function	-
ZFP69B	65243	ZFP69 zinc finger protein B	sequence-specific DNA binding transcription factor activity	Molecular function	-
TENM1	10178	teneurin transmembrane protein 1	neuropeptide signaling pathway	Biological process	-
PABPN1	8106	poly(A) binding protein, nuclear 1	poly(A)+ mRNA export from nucleus	Biological process	19364924
CREBRF	153222	CREB3 regulatory factor	positive regulation of intracellular transport	Biological process	18391022
PURA	5813	purine-rich element binding protein A	positive regulation of cell proliferation	Biological process	-
ADAM10	102	ADAM metallopeptidase domain 10	protein homodimerization activity	Molecular function	-
PICK1	9463	protein interacting with PRKCA 1	cytoskeleton	Cellular component	-
IGBP1	3476	immunoglobulin (CD79A) binding protein 1	protein phosphatase type 2A regulator activity	Molecular function	9647778
PPARD	5467	peroxisome proliferator-activated receptor delta	response to activity	Biological process	-
PDK3	5165	pyruvate dehydrogenase kinase, isozyme 3	glucose metabolic process	Biological process	-
HSF4	3299	heat shock transcription factor 4	protein phosphatase binding	Molecular function	16581800
GATA4	2626	GATA binding protein 4	ventricular cardiac muscle tissue development	Biological process	-
MTPN	136319	myotrophin	nucleus	Cellular component	-
NOTCH1	4851	notch 1	protein binding	Molecular function	10713164
GATA6	2627	GATA binding protein 6	positive regulation of cardiac muscle cell proliferation	Biological process	-
HAX1	10456	HCLS1 associated protein X-1	nuclear membrane	Cellular component	-
PAWR	5074	PRKC, apoptosis, WT1, regulator	apoptotic signaling pathway	Biological process	-
WNT10A	80326	wingless-type MMTV integration site family, member 10A	regulation of odontogenesis of dentin-containing tooth	Biological process	-
PCDHGB4	8641	protocadherin gamma subfamily B, 4	cell adhesion	Biological process	9199196
CDC16	8881	cell division cycle 16	spindle	Cellular component	7736578
AQP2	359	aquaporin 2 (collecting duct)	cellular response to mercury ion	Biological process	8584435
ACVR2B	93	activin A receptor, type IIB	positive regulation of bone mineralization	Biological process	18436533
PKD2	5311	polycystic kidney disease 2 (autosomal dominant)	calcium ion transport	Biological process	-
TAB3	257397	TGF-beta activated kinase 1/MAP3K7 binding protein 3	toll-like receptor 2 signaling pathway	Biological process	-
BCL2L14	79370	BCL2-like 14 (apoptosis facilitator)	cytoplasm	Cellular component	-
MAP3K14	9020	mitogen-activated protein kinase kinase kinase 14	stress-activated protein kinase signaling cascade	Biological process	-
EIF4H	7458	eukaryotic translation initiation factor 4H	RNA binding	Molecular function	8812460
CAMKK1	84254	calcium/calmodulin-dependent protein kinase kinase 1, alpha	protein binding	Molecular function	18242179
NME4	4833	NME/NM23 nucleoside diphosphate kinase 4	cytosol	Cellular component	-
LDHB	3945	lactate dehydrogenase B	cytosol	Cellular component	-
HHIP	64399	hedgehog interacting protein	negative regulation of smoothened signaling pathway	Biological process	11435703
SLC11A2	4891	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2	paraferritin complex	Cellular component	11842004
ADAMTS4	9507	ADAM metallopeptidase with thrombospondin type 1 motif, 4	protein binding	Molecular function	18718938
TCAF1	9747	TRPM8 channel-associated factor 1	ion channel binding	Molecular function	25559186
LPPR2	64748	lipid phosphate phosphatase-related protein type 2	dephosphorylation	Biological process	-
FLNA	2316	filamin A, alpha	extracellular exosome	Cellular component	19056867
ADCY5	111	adenylate cyclase 5	activation of phospholipase C activity	Biological process	-
FXYD1	5348	FXYD domain containing ion transport regulator 1	plasma membrane	Cellular component	-
RAG1	5896	recombination activating gene 1	protein homodimerization activity	Molecular function	-
COL19A1	1310	collagen, type XIX, alpha 1	skeletal system development	Biological process	9143499
USP1	7398	ubiquitin specific peptidase 1	regulation of DNA repair	Biological process	18082604
ENTPD8	377841	ectonucleoside triphosphate diphosphohydrolase 8	nucleoside diphosphate biosynthetic process	Biological process	-
PKHD1	5314	polycystic kidney and hepatic disease 1 (autosomal recessive)	single organismal cell-cell adhesion	Biological process	-
LUC7L	55692	LUC7-like (S. cerevisiae)	mRNA splice site selection	Biological process	-
UBE2D1	7321	ubiquitin-conjugating enzyme E2D 1	regulation of transcription from RNA polymerase II promoter in response to hypoxia	Biological process	-
CDH5	1003	cadherin 5, type 2 (vascular endothelium)	cell-cell junction organization	Biological process	-
ACTN4	81	actinin, alpha 4	protein localization to bicellular tight junction	Biological process	-
MST1R	4486	macrophage stimulating 1 receptor	defense response	Biological process	9045873
DOT1L	84444	DOT1-like histone H3K79 methyltransferase	histone methyltransferase activity (H3-K79 specific)	Molecular function	-
GSTK1	373156	glutathione S-transferase kappa 1	mitochondrial inner membrane	Cellular component	-
UGT1A10	54575	UDP glucuronosyltransferase 1 family, polypeptide A10	protein heterodimerization activity	Molecular function	20610558
F9	2158	coagulation factor IX	blood coagulation, intrinsic pathway	Biological process	-
SERPINB3	6317	serpin peptidase inhibitor, clade B (ovalbumin), member 3	viral entry into host cell	Biological process	12975381
KIAA0101	9768	KIAA0101	centrosome organization	Biological process	21673012
BMP8A	353500	bone morphogenetic protein 8a	positive regulation of pathway-restricted SMAD protein phosphorylation	Biological process	-
CST11	140880	cystatin 11	negative regulation of endopeptidase activity	Biological process	-
ZMYM4	9202	zinc finger, MYM-type 4	nucleus	Cellular component	-
ZFP36	7538	ZFP36 ring finger protein	3'-UTR-mediated mRNA stabilization	Biological process	15014438
DDX20	11218	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20	cytoplasm	Cellular component	-
COL1A1	1277	collagen, type I, alpha 1	extracellular matrix	Cellular component	22261194
TNFRSF12A	51330	tumor necrosis factor receptor superfamily, member 12A	substrate-dependent cell migration, cell attachment to substrate	Biological process	-
SOAT1	6646	sterol O-acyltransferase 1	cholesterol efflux	Biological process	15308631
HNRNPCL3	649330	heterogeneous nuclear ribonucleoprotein C-like 3	nucleus	Cellular component	-
CTCF	10664	CCCTC-binding factor (zinc finger protein)	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	8649389
SERPINE1	5054	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	positive regulation of interleukin-8 production	Biological process	19916862
XPA	7507	xeroderma pigmentosum, complementation group A	Golgi apparatus	Cellular component	-
GRIK2	2898	glutamate receptor, ionotropic, kainate 2	presynaptic membrane	Cellular component	-
TAS2R7	50837	taste receptor, type 2, member 7	integral component of membrane	Cellular component	20022913
HTR2B	3357	5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled	serotonin binding	Molecular function	15625277
TFF3	7033	trefoil factor 3 (intestinal)	molecular_function	Molecular function	-
OR5M8	219484	olfactory receptor, family 5, subfamily M, member 8	plasma membrane	Cellular component	-
FXYD3	5349	FXYD domain containing ion transport regulator 3	extracellular exosome	Cellular component	19199708
TNFRSF10A	8797	tumor necrosis factor receptor superfamily, member 10a	protease binding	Molecular function	21785459
PCSK9	255738	proprotein convertase subtilisin/kexin type 9	very-low-density lipoprotein particle receptor binding	Molecular function	18039658
ANXA13	312	annexin A13	calcium-dependent phospholipid binding	Molecular function	-
HTT	3064	huntingtin	negative regulation of extrinsic apoptotic signaling pathway	Biological process	19240112
TBCE	6905	tubulin folding cofactor E	protein folding	Biological process	8706133
ACTR3	10096	ARP3 actin-related protein 3 homolog (yeast)	focal adhesion	Cellular component	21423176
NID1	4811	nidogen 1	positive regulation of cell-substrate adhesion	Biological process	-
DAP	1611	death-associated protein	apoptotic process	Biological process	7828849
ZP1	22917	zona pellucida glycoprotein 1 (sperm receptor)	secretory granule	Cellular component	-
ZNF843	283933	zinc finger protein 843	protein binding	Molecular function	22939624
OXT	5020	oxytocin/neurophysin I prepropeptide	positive regulation of synaptic transmission	Biological process	-
MSX2	4488	msh homeobox 2	signal transduction involved in regulation of gene expression	Biological process	-
FAT1	2195	FAT atypical cadherin 1	cell-cell signaling	Biological process	8586420
GALP	85569	galanin-like peptide	regulation of appetite	Biological process	-
JUN	3725	jun proto-oncogene	poly(A) RNA binding	Molecular function	22681889
PARK2	5071	parkin RBR E3 ubiquitin protein ligase	aggresome	Cellular component	14645198
PEX5	5830	peroxisomal biogenesis factor 5	peroxisome targeting sequence binding	Molecular function	18346465
HLTF	6596	helicase-like transcription factor	ubiquitin protein ligase activity	Molecular function	-
LMBR1L	55716	limb development membrane protein 1-like	integral component of membrane	Cellular component	-
CDC42BPB	9578	CDC42 binding protein kinase beta (DMPK-like)	cell-cell junction	Cellular component	-
AXIN1	8312	axin 1	negative regulation of fat cell differentiation	Biological process	-
RBP4	5950	retinol binding protein 4, plasma	cytosol	Cellular component	-
TLR9	54106	toll-like receptor 9	cytoplasm	Cellular component	19740627
TCN1	6947	transcobalamin I (vitamin B12 binding protein, R binder family)	extracellular region	Cellular component	-
DMXL2	23312	Dmx-like 2	cell junction	Cellular component	-
CEP89	84902	centrosomal protein 89kDa	nonmotile primary cilium assembly	Biological process	23789104
PLIN2	123	perilipin 2	endoplasmic reticulum	Cellular component	9003395
DCXR	51181	dicarbonyl/L-xylulose reductase	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	Molecular function	19442656
AEBP1	165	AE binding protein 1	zinc ion binding	Molecular function	-
STK38L	23012	serine/threonine kinase 38 like	magnesium ion binding	Molecular function	15067004
PTGR1	22949	prostaglandin reductase 1	small molecule metabolic process	Biological process	-
NTRK2	4915	neurotrophic tyrosine kinase, receptor, type 2	positive regulation of gene expression	Biological process	-
SNUPN	10073	snurportin 1	extracellular exosome	Cellular component	23376485
SLC23A1	9963	solute carrier family 23 (ascorbic acid transporter), member 1	sodium-dependent L-ascorbate transmembrane transporter activity	Molecular function	10631088
ADORA2A	135	adenosine A2a receptor	postsynaptic density	Cellular component	-
SCLT1	132320	sodium channel and clathrin linker 1	clustering of voltage-gated sodium channels	Biological process	-
BDH1	622	3-hydroxybutyrate dehydrogenase, type 1	liver development	Biological process	-
IL5RA	3568	interleukin 5 receptor, alpha	integral component of membrane	Cellular component	-
OR10G8	219869	olfactory receptor, family 10, subfamily G, member 8	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
FNTA	2339	farnesyltransferase, CAAX box, alpha	microtubule associated complex	Cellular component	19228685
IL6	3569	interleukin 6	response to calcium ion	Biological process	-
ZNF589	51385	zinc finger protein 589	metal ion binding	Molecular function	-
POLR2E	5434	polymerase (RNA) II (DNA directed) polypeptide E, 25kDa	nucleus	Cellular component	9852112
PPP6C	5537	protein phosphatase 6, catalytic subunit	protein serine/threonine phosphatase activity	Molecular function	16716191
ZBTB8B	728116	zinc finger and BTB domain containing 8B	DNA binding	Molecular function	-
NEU1	4758	sialidase 1 (lysosomal sialidase)	cellular protein metabolic process	Biological process	-
SIX1	6495	SIX homeobox 1	kidney development	Biological process	-
CTSH	1512	cathepsin H	cysteine-type endopeptidase activity	Molecular function	2849458
PKMYT1	9088	protein kinase, membrane associated tyrosine/threonine 1	protein phosphorylation	Biological process	-
CARNS1	57571	carnosine synthase 1	metal ion binding	Molecular function	-
MYBPC3	4607	myosin binding protein C, cardiac	striated muscle myosin thick filament	Cellular component	-
ZNF587	84914	zinc finger protein 587	DNA binding	Molecular function	-
PLA2G5	5322	phospholipase A2, group V	response to cAMP	Biological process	-
POP1	10940	processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)	ribonuclease MRP complex	Cellular component	8918471
WNT5A	7474	wingless-type MMTV integration site family, member 5A	negative regulation of epithelial cell proliferation	Biological process	-
RAP1BL	643752	RAP1B, member of RAS oncogene family pseudogene	GTP binding	Molecular function	-
PPP1R9B	84687	protein phosphatase 1, regulatory subunit 9B	regulation of exit from mitosis	Biological process	11278317
CLIC1	1192	chloride intracellular channel 1	blood microparticle	Cellular component	22516433
CCL4	6351	chemokine (C-C motif) ligand 4	cell-cell signaling	Biological process	2521882
HDAC10	83933	histone deacetylase 10	NAD-dependent histone deacetylase activity (H4-K16 specific)	Molecular function	-
MAPK4	5596	mitogen-activated protein kinase 4	MAPK cascade	Biological process	7969157
COG3	83548	component of oligomeric golgi complex 3	Golgi apparatus	Cellular component	-
HSPA5	3309	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	midbody	Cellular component	15166316
FZD3	7976	frizzled class receptor 3	hair follicle development	Biological process	-
PIDD1	55367	p53-induced death domain protein 1	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	Biological process	21726810
AGT	183	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	response to salt stress	Biological process	-
FZD9	8326	frizzled class receptor 9	neuroblast proliferation	Biological process	-
FKBP8	23770	FK506 binding protein 8, 38kDa	negative regulation of apoptotic process	Biological process	-
IL6R	3570	interleukin 6 receptor	plasma membrane	Cellular component	-
AQP1	358	aquaporin 1 (Colton blood group)	metanephric descending thin limb development	Biological process	-
FPGS	2356	folylpolyglutamate synthase	liver development	Biological process	-
SYVN1	84447	synovial apoptosis inhibitor 1, synoviolin	endoplasmic reticulum	Cellular component	23710284
ATP6V0C	527	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c	proton-transporting ATP synthase activity, rotational mechanism	Molecular function	1709739
BCL11A	53335	B-cell CLL/lymphoma 11A (zinc finger protein)	protein sumoylation	Biological process	-
UGT2B17	7367	UDP glucuronosyltransferase 2 family, polypeptide B17	integral component of membrane	Cellular component	-
OGG1	4968	8-oxoguanine DNA glycosylase	damaged DNA binding	Molecular function	-
ENO1	2023	enolase 1, (alpha)	phosphopyruvate hydratase activity	Molecular function	-
ARF4	378	ADP-ribosylation factor 4	protein transport	Biological process	-
MAP4K1	11184	mitogen-activated protein kinase kinase kinase kinase 1	activation of JUN kinase activity	Biological process	8824585
SCART1	619207	scavenger receptor protein family member	receptor-mediated endocytosis	Biological process	-
AANAT	15	aralkylamine N-acetyltransferase	response to zinc ion	Biological process	-
LTF	4057	lactotransferrin	ossification	Biological process	-
TBXA2R	6915	thromboxane A2 receptor	blood coagulation	Biological process	-
EDAR	10913	ectodysplasin A receptor	salivary gland cavitation	Biological process	-
NDST1	3340	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	deacetylase activity	Molecular function	-
COL3A1	1281	collagen, type III, alpha 1	transforming growth factor beta receptor signaling pathway	Biological process	16360482
PREP	5550	prolyl endopeptidase	serine-type peptidase activity	Molecular function	7959018
ARVCF	421	armadillo repeat gene deleted in velocardiofacial syndrome	cell junction	Cellular component	-
LSM11	134353	LSM11, U7 small nuclear RNA associated	nucleus	Cellular component	-
TIMM50	92609	translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)	nuclear speck	Cellular component	16008839
CA9	768	carbonic anhydrase IX	integral component of membrane	Cellular component	-
ANXA9	8416	annexin A9	extracellular exosome	Cellular component	23376485
RPS4X	6191	ribosomal protein S4, X-linked	polysome	Cellular component	8139551
OR2D3	120775	olfactory receptor, family 2, subfamily D, member 3	G-protein coupled receptor signaling pathway	Biological process	-
PAPOLG	64895	poly(A) polymerase gamma	mRNA polyadenylation	Biological process	-
STAT5A	6776	signal transducer and activator of transcription 5A	Peyer's patch development	Biological process	-
ALDH6A1	4329	aldehyde dehydrogenase 6 family, member A1	mitochondrion	Cellular component	1527093
ASNS	440	asparagine synthetase (glutamine-hydrolyzing)	response to follicle-stimulating hormone	Biological process	-
BRK1	55845	BRICK1, SCAR/WAVE actin-nucleating complex subunit	positive regulation of cell proliferation	Biological process	-
CALCOCO1	57658	calcium binding and coiled-coil domain 1	nucleus	Cellular component	-
NUDT4	11163	nudix (nucleoside diphosphate linked moiety X)-type motif 4	inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity	Molecular function	-
ZNF662	389114	zinc finger protein 662	protein binding	Molecular function	25416956
IFT20	90410	intraflagellar transport 20	ciliary tip	Cellular component	-
S100B	6285	S100 calcium binding protein B	regulation of neuronal synaptic plasticity	Biological process	-
NDFIP1	80762	Nedd4 family interacting protein 1	negative regulation of gene expression	Biological process	18776082
RELN	5649	reelin	axon guidance	Biological process	-
LMO4	8543	LIM domain only 4	transcription from RNA polymerase II promoter	Biological process	-
PXK	54899	PX domain containing serine/threonine kinase	ATP binding	Molecular function	16142408
TIMM10	26519	translocase of inner mitochondrial membrane 10 homolog (yeast)	mitochondrion	Cellular component	-
ATP6V1C2	245973	ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2	protein dimerization activity	Molecular function	21356312
HSD17B4	3295	hydroxysteroid (17-beta) dehydrogenase 4	3-hydroxyacyl-CoA dehydrogenase activity	Molecular function	-
SLC22A5	6584	solute carrier family 22 (organic cation/carnitine transporter), member 5	PDZ domain binding	Molecular function	15523054
PTH	5741	parathyroid hormone	parathyroid hormone receptor binding	Molecular function	-
MDM2	4193	MDM2 proto-oncogene, E3 ubiquitin protein ligase	cellular response to alkaloid	Biological process	-
ZG16	653808	zymogen granule protein 16	Golgi lumen	Cellular component	17307141
HIST1H2AL	8332	histone cluster 1, H2al	DNA binding	Molecular function	-
IFI30	10437	interferon, gamma-inducible protein 30	cytoplasm	Cellular component	-
PRAMEF2	65122	PRAME family member 2	negative regulation of retinoic acid receptor signaling pathway	Biological process	-
ACADM	34	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	medium-chain fatty acid catabolic process	Biological process	1970566
CXCL12	6387	chemokine (C-X-C motif) ligand 12	positive regulation of monocyte chemotaxis	Biological process	18802065
ARSB	411	arylsulfatase B	regulation of epithelial cell migration	Biological process	19306108
CHST11	50515	carbohydrate (chondroitin 4) sulfotransferase 11	polysaccharide localization	Biological process	-
PNPLA7	375775	patatin-like phospholipase domain containing 7	lysophospholipase activity	Molecular function	-
ASCC3	10973	activating signal cointegrator 1 complex subunit 3	Golgi apparatus	Cellular component	-
NCOA3	8202	nuclear receptor coactivator 3	nucleoplasm	Cellular component	-
CCNH	902	cyclin H	regulation of gene expression, epigenetic	Biological process	-
CYP11A1	1583	cytochrome P450, family 11, subfamily A, polypeptide 1	hippocampus development	Biological process	-
TPM3	7170	tropomyosin 3	extracellular exosome	Cellular component	20458337
T	6862	T, brachyury homolog (mouse)	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
LEF1	51176	lymphoid enhancer-binding factor 1	trachea gland development	Biological process	-
MEF2C	4208	myocyte enhancer factor 2C	B cell homeostasis	Biological process	-
BZRAP1	9256	benzodiazepine receptor (peripheral) associated protein 1	mitochondrion	Cellular component	9915832
SOX11	6664	SRY (sex determining region Y)-box 11	positive regulation of transcription from RNA polymerase II promoter	Biological process	21124928
PTAFR	5724	platelet-activating factor receptor	G-protein coupled purinergic nucleotide receptor signaling pathway	Biological process	-
OR5P3	120066	olfactory receptor, family 5, subfamily P, member 3	G-protein coupled receptor signaling pathway	Biological process	-
PPP2CA	5515	protein phosphatase 2, catalytic subunit, alpha isozyme	mitochondrion	Cellular component	11007961
LTA	4049	lymphotoxin alpha	humoral immune response	Biological process	-
PAFAH1B3	5050	platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)	membrane	Cellular component	19946888
GRM3	2913	glutamate receptor, metabotropic 3	postsynaptic membrane	Cellular component	-
BTNL9	153579	butyrophilin-like 9	integral component of membrane	Cellular component	-
EID2	163126	EP300 interacting inhibitor of differentiation 2	transforming growth factor beta receptor complex assembly	Biological process	14612439
HAUS2	55142	HAUS augmin-like complex, subunit 2	centrosome organization	Biological process	19427217
CCL2	6347	chemokine (C-C motif) ligand 2	maternal process involved in female pregnancy	Biological process	-
SS18L1	26039	synovial sarcoma translocation gene on chromosome 18-like 1	positive regulation of transcription, DNA-templated	Biological process	-
OXLD1	339229	oxidoreductase-like domain containing 1	mitochondrion	Cellular component	-
HNRNPH1	3187	heterogeneous nuclear ribonucleoprotein H1 (H)	mRNA splicing, via spliceosome	Biological process	-
KPNA3	3839	karyopherin alpha 3 (importin alpha 4)	protein C-terminus binding	Molecular function	-
SLC39A5	283375	solute carrier family 39 (zinc transporter), member 5	cellular response to zinc ion starvation	Biological process	-
GPN2	54707	GPN-loop GTPase 2	hydrolase activity	Molecular function	-
PCGF2	7703	polycomb group ring finger 2	protein ubiquitination	Biological process	-
ERCC4	2072	excision repair cross-complementation group 4	resolution of meiotic recombination intermediates	Biological process	-
FLVCR1	28982	feline leukemia virus subgroup C cellular receptor 1	cellular iron ion homeostasis	Biological process	-
CACNA1A	773	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	cell projection	Cellular component	16595610
APOB	338	apolipoprotein B	neuronal cell body	Cellular component	22897442
CCNG1	900	cyclin G1	mitotic G2 DNA damage checkpoint	Biological process	-
NR2F2	7026	nuclear receptor subfamily 2, group F, member 2	ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity	Molecular function	18798693
INPP5A	3632	inositol polyphosphate-5-phosphatase, 40kDa	membrane	Cellular component	8006039
NFASC	23114	neurofascin	focal adhesion	Cellular component	21423176
MDH2	4191	malate dehydrogenase 2, NAD (mitochondrial)	mitochondrion	Cellular component	-
PARK2	5071	parkin RBR E3 ubiquitin protein ligase	negative regulation of reactive oxygen species metabolic process	Biological process	18541373
PLCB3	5331	phospholipase C, beta 3 (phosphatidylinositol-specific)	membrane	Cellular component	-
BRD7	29117	bromodomain containing 7	transcription regulatory region DNA binding	Molecular function	20228809
KIF4B	285643	kinesin family member 4B	nucleoplasm	Cellular component	-
FTH1	2495	ferritin, heavy polypeptide 1	protein binding	Molecular function	15607035
SEC61G	23480	Sec61 gamma subunit	cytosol	Cellular component	-
SP4	6671	Sp4 transcription factor	transcription from RNA polymerase II promoter	Biological process	-
SERPINB5	5268	serpin peptidase inhibitor, clade B (ovalbumin), member 5	prostate gland morphogenesis	Biological process	-
ZNF705G	100131980	zinc finger protein 705G	DNA binding	Molecular function	-
HESX1	8820	HESX homeobox 1	chromatin binding	Molecular function	-
MR1	3140	major histocompatibility complex, class I-related	antigen processing and presentation	Biological process	-
CHUK	1147	conserved helix-loop-helix ubiquitous kinase	nucleotide-binding oligomerization domain containing signaling pathway	Biological process	-
ITGA2	3673	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	positive regulation of cell adhesion	Biological process	-
FRMD5	84978	FERM domain containing 5	cytoplasm	Cellular component	-
OCM	654231	oncomodulin	calcium ion binding	Molecular function	8354278
RPS6KA6	27330	ribosomal protein S6 kinase, 90kDa, polypeptide 6	negative regulation of ERK1 and ERK2 cascade	Biological process	-
MYH10	4628	myosin, heavy chain 10, non-muscle	spindle	Cellular component	-
ATL3	25923	atlastin GTPase 3	Golgi organization	Biological process	18270207
OR4C16	219428	olfactory receptor, family 4, subfamily C, member 16 (gene/pseudogene)	transmembrane signaling receptor activity	Molecular function	-
FZD7	8324	frizzled class receptor 7	regulation of transcription, DNA-templated	Biological process	18681827
DDX60	55601	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	response to virus	Biological process	21791617
TEAD3	7005	TEA domain family member 3	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
PKD1	5310	polycystic kidney disease 1 (autosomal dominant)	cytoplasm	Cellular component	-
LHX6	26468	LIM homeobox 6	sequence-specific DNA binding transcription factor activity	Molecular function	10393337
PTH2	113091	parathyroid hormone 2	neuropeptide signaling pathway	Biological process	-
RCVRN	5957	recoverin	calcium ion binding	Molecular function	-
SIRT1	23411	sirtuin 1	single strand break repair	Biological process	20097625
APOA4	337	apolipoprotein A-IV	cholesterol transporter activity	Molecular function	1935934
INTU	27152	inturned planar cell polarity protein	negative regulation of keratinocyte proliferation	Biological process	-
PVRL1	5818	poliovirus receptor-related 1 (herpesvirus entry mediator C)	growth cone membrane	Cellular component	-
KIFAP3	22920	kinesin-associated protein 3	negative regulation of cell proliferation	Biological process	-
DEFB124	245937	defensin, beta 124	cell surface	Cellular component	-
NRG4	145957	neuregulin 4	epidermal growth factor receptor signaling pathway	Biological process	-
LRRK1	79705	leucine-rich repeat kinase 1	identical protein binding	Molecular function	19712061
OBSCN	84033	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	ankyrin binding	Molecular function	18782775
NCK1	4690	NCK adaptor protein 1	positive regulation of T cell proliferation	Biological process	12110186
PHKG1	5260	phosphorylase kinase, gamma 1 (muscle)	carbohydrate metabolic process	Biological process	-
TLL1	7092	tolloid-like 1	cell differentiation	Biological process	-
TTN	7273	titin	actinin binding	Molecular function	11846417
PTCHD1	139411	patched domain containing 1	cognition	Biological process	20844286
BLK	640	BLK proto-oncogene, Src family tyrosine kinase	protein tyrosine kinase activity	Molecular function	7845672
POLR2K	5440	polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa	transcription initiation from RNA polymerase I promoter	Biological process	-
THAP11	57215	THAP domain containing 11	transcription, DNA-templated	Biological process	-
SLC25A27	9481	solute carrier family 25, member 27	generation of precursor metabolites and energy	Biological process	10025957
PTPMT1	114971	protein tyrosine phosphatase, mitochondrial 1	glycerophospholipid biosynthetic process	Biological process	-
DYRK1A	1859	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	protein serine/threonine/tyrosine kinase activity	Molecular function	-
LRP1	4035	low density lipoprotein receptor-related protein 1	protein kinase C-activating G-protein coupled receptor signaling pathway	Biological process	-
SERINC1	57515	serine incorporator 1	extracellular exosome	Cellular component	23376485
CSF1	1435	colony stimulating factor 1 (macrophage)	ossification	Biological process	-
RFFL	117584	ring finger and FYVE-like domain containing E3 ubiquitin protein ligase	ligase activity	Molecular function	-
OAS1	4938	2'-5'-oligoadenylate synthetase 1, 40/46kDa	nucleus	Cellular component	-
NGFR	4804	nerve growth factor receptor	nerve development	Biological process	-
ZNF333	84449	zinc finger protein 333	nucleus	Cellular component	-
DAPK1	1612	death-associated protein kinase 1	intracellular signal transduction	Biological process	10629061
CAD	790	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	lactation	Biological process	-
CSDE1	7812	cold shock domain containing E1, RNA-binding	DNA binding	Molecular function	-
CYP2C9	1559	cytochrome P450, family 2, subfamily C, polypeptide 9	oxidation-reduction process	Biological process	16401082
USF1	7391	upstream transcription factor 1	protein homodimerization activity	Molecular function	2249772
KIT	3815	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	metal ion binding	Molecular function	-
STK36	27148	serine/threonine kinase 36	positive regulation of smoothened signaling pathway	Biological process	-
MB21D1	115004	Mab-21 domain containing 1	cyclic nucleotide biosynthetic process	Biological process	23258413
VEZF1	7716	vascular endothelial zinc finger 1	cellular defense response	Biological process	8035792
VPS35	55737	vacuolar protein sorting 35 homolog (S. cerevisiae)	protein binding	Molecular function	11102511
MORF4L2	9643	mortality factor 4 like 2	chromatin organization	Biological process	-
BLVRA	644	biliverdin reductase A	protein binding	Molecular function	25416956
MEF2A	4205	myocyte enhancer factor 2A	toll-like receptor 3 signaling pathway	Biological process	-
RPRD1B	58490	regulation of nuclear pre-mRNA domain containing 1B	positive regulation of cell proliferation	Biological process	22264791
GRN	2896	granulin	signal transduction	Biological process	1542665
AGXT	189	alanine-glyoxylate aminotransferase	peroxisomal matrix	Cellular component	-
EPS8	2059	epidermal growth factor receptor pathway substrate 8	actin cytoskeleton reorganization	Biological process	-
NPPB	4879	natriuretic peptide B	regulation of blood vessel size	Biological process	-
IRF2	3660	interferon regulatory factor 2	RNA polymerase II regulatory region sequence-specific DNA binding	Molecular function	9540062
SFRP1	6422	secreted frizzled-related protein 1	regulation of angiogenesis	Biological process	-
AFF4	27125	AF4/FMR2 family, member 4	regulation of transcription, DNA-templated	Biological process	-
PGS1	9489	phosphatidylglycerophosphate synthase 1	phosphatidylglycerol biosynthetic process	Biological process	-
SIRT2	22933	sirtuin 2	positive regulation of attachment of spindle microtubules to kinetochore	Biological process	-
GTF2H4	2968	general transcription factor IIH, polypeptide 4, 52kDa	core TFIIH complex	Cellular component	-
TAZ	6901	tafazzin	1-acylglycerophosphocholine O-acyltransferase activity	Molecular function	12930833
IKBKB	3551	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	cellular response to tumor necrosis factor	Biological process	23091055
CCBL2	56267	cysteine conjugate-beta lyase 2	poly(A) RNA binding	Molecular function	22681889
PARK7	11315	parkinson protein 7	negative regulation of protein export from nucleus	Biological process	15983381
NUPL1	9818	nucleoporin like 1	mitotic cell cycle	Biological process	-
ATP6V1H	51606	ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H	interaction with host	Biological process	-
ETNK1	55500	ethanolamine kinase 1	phosphatidylethanolamine biosynthetic process	Biological process	-
OTOA	146183	otoancorin	apical plasma membrane	Cellular component	-
SULT1A1	6817	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1	catecholamine metabolic process	Biological process	-
SELT	51714	selenoprotein T	selenocysteine incorporation	Biological process	10567350
RPP25L	138716	ribonuclease P/MRP 25kDa subunit-like	protein binding	Molecular function	25416956
NR2E1	7101	nuclear receptor subfamily 2, group E, member 1	zinc ion binding	Molecular function	-
TRIM4	89122	tripartite motif containing 4	ligase activity	Molecular function	-
TRNT1	51095	tRNA nucleotidyl transferase, CCA-adding, 1	tRNA 3'-terminal CCA addition	Biological process	25193871
NQO1	1728	NAD(P)H dehydrogenase, quinone 1	response to toxic substance	Biological process	10393963
PLA2G4A	5321	phospholipase A2, group IVA (cytosolic, calcium-dependent)	phospholipase A2 activity	Molecular function	-
CASP3	836	caspase 3, apoptosis-related cysteine peptidase	cysteine-type endopeptidase activity	Molecular function	-
SLC22A4	6583	solute carrier family 22 (organic cation/zwitterion transporter), member 4	secondary active organic cation transmembrane transporter activity	Molecular function	9426230
S1PR3	1903	sphingosine-1-phosphate receptor 3	negative regulation of establishment of endothelial barrier	Biological process	24851274
DMXL2	23312	Dmx-like 2	synaptic vesicle	Cellular component	11809763
PGM3	5238	phosphoglucomutase 3	magnesium ion binding	Molecular function	-
VAMP4	8674	vesicle-associated membrane protein 4	exocytosis	Biological process	-
RRAS2	22800	related RAS viral (r-ras) oncogene homolog 2	focal adhesion	Cellular component	21423176
CNGB1	1258	cyclic nucleotide gated channel beta 1	visual perception	Biological process	7682292
PCGF3	10336	polycomb group ring finger 3	nucleoplasm	Cellular component	-
SLC4A7	9497	solute carrier family 4, sodium bicarbonate cotransporter, member 7	retinal cell programmed cell death	Biological process	-
MYCBPAP	84073	MYCBP associated protein	cell differentiation	Biological process	-
U2AF2	11338	U2 small nuclear RNA auxiliary factor 2	gene expression	Biological process	-
CDKN2D	1032	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	G1/S transition of mitotic cell cycle	Biological process	10208428
CDK7	1022	cyclin-dependent kinase 7	transcription-coupled nucleotide-excision repair	Biological process	-
TP53TG3B	729355	TP53 target 3B	nucleus	Cellular component	-
MAPK7	5598	mitogen-activated protein kinase 7	toll-like receptor 3 signaling pathway	Biological process	-
ALOX15	246	arachidonate 15-lipoxygenase	lipid particle	Cellular component	19528634
SLC36A1	206358	solute carrier family 36 (proton/amino acid symporter), member 1	ion transport	Biological process	-
TEFM	79736	transcription elongation factor, mitochondrial	regulation of transcription, DNA-templated	Biological process	-
PIK3R6	146850	phosphoinositide-3-kinase, regulatory subunit 6	phosphatidylinositol phosphorylation	Biological process	-
ATL3	25923	atlastin GTPase 3	GTPase activity	Molecular function	18270207
PHEX	5251	phosphate regulating endopeptidase homolog, X-linked	organophosphate metabolic process	Biological process	-
RPS17	6218	ribosomal protein S17	ribosomal small subunit biogenesis	Biological process	18697920
JUN	3725	jun proto-oncogene	liver development	Biological process	-
FGD2	221472	FYVE, RhoGEF and PH domain containing 2	regulation of cell shape	Biological process	-
TMED5	50999	transmembrane emp24 protein transport domain containing 5	cis-Golgi network	Cellular component	19948005
RBM14	10432	RNA binding motif protein 14	histone deacetylation	Biological process	11443112
VASP	7408	vasodilator-stimulated phosphoprotein	protein binding	Molecular function	16631741
RBM39	9584	RNA binding motif protein 39	RNA splicing	Biological process	-
UNC5D	137970	unc-5 homolog D (C. elegans)	cell surface	Cellular component	-
TNNI3K	51086	TNNI3 interacting kinase	protein serine/threonine kinase activity	Molecular function	-
VIM	7431	vimentin	cytoskeleton	Cellular component	16130169
SLC23A1	9963	solute carrier family 23 (ascorbic acid transporter), member 1	vitamin metabolic process	Biological process	-
TGFA	7039	transforming growth factor, alpha	positive regulation of epidermal growth factor-activated receptor activity	Biological process	11278323
BCL2L2	599	BCL2-like 2	extrinsic apoptotic signaling pathway in absence of ligand	Biological process	-
RBM19	9904	RNA binding motif protein 19	multicellular organismal development	Biological process	-
TNKS	8658	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase	chromosome, telomeric region	Cellular component	9822378
TNKS1BP1	85456	tankyrase 1 binding protein 1, 182kDa	CCR4-NOT complex	Cellular component	19558367
SHMT1	6470	serine hydroxymethyltransferase 1 (soluble)	protein homotetramerization	Biological process	-
CRYZ	1429	crystallin, zeta (quinone reductase)	xenobiotic catabolic process	Biological process	17497241
ADAMTSL3	57188	ADAMTS-like 3	proteinaceous extracellular matrix	Cellular component	-
GPR139	124274	G protein-coupled receptor 139	protein dimerization activity	Molecular function	-
CD28	940	CD28 molecule	neurotrophin TRK receptor signaling pathway	Biological process	-
PPAP2B	8613	phosphatidic acid phosphatase type 2B	negative regulation of protein phosphorylation	Biological process	20123964
MMP24	10893	matrix metallopeptidase 24 (membrane-inserted)	neuronal stem cell maintenance	Biological process	-
CRY1	1407	cryptochrome circadian clock 1	DNA damage induced protein phosphorylation	Biological process	-
SEC61A2	55176	Sec61 alpha 2 subunit (S. cerevisiae)	endoplasmic reticulum unfolded protein response	Biological process	-
CLN8	2055	ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)	ceramide metabolic process	Biological process	16086686
TRIOBP	11078	TRIO and F-actin binding protein	midbody	Cellular component	-
FGF23	8074	fibroblast growth factor 23	positive regulation of ERK1 and ERK2 cascade	Biological process	-
MAPK11	5600	mitogen-activated protein kinase 11	gene expression	Biological process	-
DEF8	54849	differentially expressed in FDCP 8 homolog (mouse)	intracellular signal transduction	Biological process	-
ALDH6A1	4329	aldehyde dehydrogenase 6 family, member A1	poly(A) RNA binding	Molecular function	22658674
AGXT2	64902	alanine--glyoxylate aminotransferase 2	pyridoxal phosphate binding	Molecular function	-
ADGRL1	22859	adhesion G protein-coupled receptor L1	latrotoxin receptor activity	Molecular function	-
L2HGDH	79944	L-2-hydroxyglutarate dehydrogenase	small molecule metabolic process	Biological process	-
TFCP2	7024	transcription factor CP2	DNA binding	Molecular function	8035790
CYP27A1	1593	cytochrome P450, family 27, subfamily A, polypeptide 1	cholesterol metabolic process	Biological process	-
CHN1	1123	chimerin 1	positive regulation of GTPase activity	Biological process	-
VANGL2	57216	VANGL planar cell polarity protein 2	stress fiber	Cellular component	-
FOXO3	2309	forkhead box O3	positive regulation of erythrocyte differentiation	Biological process	14734530
ARSB	411	arylsulfatase B	rough endoplasmic reticulum	Cellular component	-
KRT2	3849	keratin 2, type II	cytoplasm	Cellular component	-
ABR	29	active BCR-related	regulation of small GTPase mediated signal transduction	Biological process	-
FGF12	2257	fibroblast growth factor 12	protein binding	Molecular function	25416956
CXCL11	6373	chemokine (C-X-C motif) ligand 11	inflammatory response	Biological process	-
MAP2K1	5604	mitogen-activated protein kinase kinase 1	microtubule	Cellular component	-
NDUFAF5	79133	NADH dehydrogenase (ubiquinone) complex I, assembly factor 5	extrinsic component of mitochondrial inner membrane	Cellular component	18940309
IGFBP1	3484	insulin-like growth factor binding protein 1	signal transduction	Biological process	2454104
PDHA2	5161	pyruvate dehydrogenase (lipoamide) alpha 2	glycolytic process	Biological process	-
HCN1	348980	hyperpolarization activated cyclic nucleotide gated potassium channel 1	synaptic transmission	Biological process	-
TNF	7124	tumor necrosis factor	negative regulation of cell proliferation	Biological process	-
SHH	6469	sonic hedgehog	negative regulation of ureter smooth muscle cell differentiation	Biological process	-
DCSTAMP	81501	dendrocyte expressed seven transmembrane protein	integral component of plasma membrane	Cellular component	20586129
POLG	5428	polymerase (DNA directed), gamma	DNA binding	Molecular function	-
KRT75	9119	keratin 75, type II	keratin filament	Cellular component	-
MRPL45	84311	mitochondrial ribosomal protein L45	protein binding	Molecular function	25416956
ANKRD1	27063	ankyrin repeat domain 1 (cardiac muscle)	cellular response to tumor necrosis factor	Biological process	7730328
TRIM21	6737	tripartite motif containing 21	regulation of type I interferon production	Biological process	-
VPS13D	55187	vacuolar protein sorting 13 homolog D (S. cerevisiae)	intracellular	Cellular component	-
CNGA2	1260	cyclic nucleotide gated channel alpha 2	Golgi membrane	Cellular component	-
CALD1	800	caldesmon 1	tropomyosin binding	Molecular function	1555769
TNFSF10	8743	tumor necrosis factor (ligand) superfamily, member 10	extrinsic apoptotic signaling pathway	Biological process	-
RAB11FIP3	9727	RAB11 family interacting protein 3 (class II)	protein homodimerization activity	Molecular function	17030804
GRIK1	2897	glutamate receptor, ionotropic, kainate 1	adult behavior	Biological process	-
CYP3A4	1576	cytochrome P450, family 3, subfamily A, polypeptide 4	testosterone 6-beta-hydroxylase activity	Molecular function	3259858
CDS1	1040	CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1	small molecule metabolic process	Biological process	-
COL8A2	1296	collagen, type VIII, alpha 2	protein binding, bridging	Molecular function	2019595
IGSF1	3547	immunoglobulin superfamily, member 1	signal transduction	Biological process	11266516
SLC25A19	60386	solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19	positive regulation of defense response to virus by host	Biological process	22020285
CSNK2A1	1457	casein kinase 2, alpha 1 polypeptide	NuRD complex	Cellular component	17827154
PRDM14	63978	PR domain containing 14	transcription, DNA-templated	Biological process	-
KLF4	9314	Kruppel-like factor 4 (gut)	cellular response to hydrogen peroxide	Biological process	-
ERN1	2081	endoplasmic reticulum to nucleus signaling 1	peptidyl-serine trans-autophosphorylation	Biological process	21317875
OGT	8473	O-linked N-acetylglucosamine (GlcNAc) transferase	signal transduction	Biological process	9083067
UGT1A1	54658	UDP glucuronosyltransferase 1 family, polypeptide A1	acute-phase response	Biological process	-
HTR2A	3356	5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled	positive regulation of ERK1 and ERK2 cascade	Biological process	19057895
VCL	7414	vinculin	blood coagulation	Biological process	-
BNIP1	662	BCL2/adenovirus E1B 19kDa interacting protein 1	endoplasmic reticulum membrane fusion	Biological process	15272311
MYF6	4618	myogenic factor 6 (herculin)	nucleoplasm	Cellular component	-
RPTOR	57521	regulatory associated protein of MTOR, complex 1	transcription initiation from RNA polymerase II promoter	Biological process	-
GNG12	55970	guanine nucleotide binding protein (G protein), gamma 12	signal transducer activity	Molecular function	-
CPLX1	10815	complexin 1	neuronal cell body	Cellular component	-
ZNF460	10794	zinc finger protein 460	metal ion binding	Molecular function	-
SNW1	22938	SNW domain containing 1	viral process	Biological process	-
RANBP2	5903	RAN binding protein 2	membrane	Cellular component	19946888
MECP2	4204	methyl CpG binding protein 2	glucocorticoid metabolic process	Biological process	-
ARHGEF7	8874	Rho guanine nucleotide exchange factor (GEF) 7	hematopoietic progenitor cell differentiation	Biological process	-
SPPL3	121665	signal peptide peptidase like 3	aspartic endopeptidase activity, intramembrane cleaving	Molecular function	16873890
CCND3	896	cyclin D3	T cell proliferation	Biological process	-
RNPS1	10921	RNA binding protein S1, serine-rich domain	nucleotide binding	Molecular function	-
PTEN	5728	phosphatase and tensin homolog	phosphatidylinositol-3-phosphatase activity	Molecular function	9811831
BCL10	8915	B-cell CLL/lymphoma 10	positive regulation of mast cell cytokine production	Biological process	16647297
EDN3	1908	endothelin 3	regulation of vasoconstriction	Biological process	-
SULT2A1	6822	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	small molecule metabolic process	Biological process	-
GALNT4	8693	polypeptide N-acetylgalactosaminyltransferase 4	polypeptide N-acetylgalactosaminyltransferase activity	Molecular function	-
SIK2	23235	salt-inducible kinase 2	cytoplasm	Cellular component	-
HLA-DRB5	3127	major histocompatibility complex, class II, DR beta 5	extracellular space	Cellular component	16502470
RAB42	115273	RAB42, member RAS oncogene family	Golgi apparatus	Cellular component	-
MAP3K10	4294	mitogen-activated protein kinase kinase kinase 10	activation of JNKK activity	Biological process	-
COPS5	10987	COP9 signalosome subunit 5	ubiquitin-specific protease activity	Molecular function	19246649
BIRC2	329	baculoviral IAP repeat containing 2	XY body	Cellular component	-
ABCF3	55324	ATP-binding cassette, sub-family F (GCN20), member 3	protein binding	Molecular function	21516116
CD93	22918	CD93 molecule	macrophage activation	Biological process	9047234
NDUFA13	51079	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13	nucleoplasm	Cellular component	10924506
ATP6V1G3	127124	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3	vacuolar proton-transporting V-type ATPase complex	Cellular component	-
RORB	6096	RAR-related orphan receptor B	transcription factor binding	Molecular function	-
SNX3	8724	sorting nexin 3	extrinsic component of membrane	Cellular component	-
RASL12	51285	RAS-like, family 12	GTP binding	Molecular function	-
PILRA	29992	paired immunoglobin-like type 2 receptor alpha	protein binding	Molecular function	10660620
STMN1	3925	stathmin 1	extracellular exosome	Cellular component	20458337
SMG7	9887	SMG7 nonsense mediated mRNA decay factor	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Biological process	16488880
POLR1D	51082	polymerase (RNA) I polypeptide D, 16kDa	protein binding	Molecular function	16189514
SH3BP2	6452	SH3-domain binding protein 2	positive regulation of signal transduction	Biological process	9299232
COMMD8	54951	COMM domain containing 8	transcription, DNA-templated	Biological process	-
CDK13	8621	cyclin-dependent kinase 13	cytoplasm	Cellular component	-
ETS1	2113	v-ets avian erythroblastosis virus E26 oncogene homolog 1	positive regulation of erythrocyte differentiation	Biological process	8620536
LYPLA2	11313	lysophospholipase II	hydrolase activity	Molecular function	-
RPGRIP1L	23322	RPGRIP1-like	in utero embryonic development	Biological process	-
NUP210L	91181	nucleoporin 210kDa-like	integral component of membrane	Cellular component	-
PRDM5	11107	PR domain containing 5	sequence-specific DNA binding	Molecular function	17636019
KRTAP10-2	386679	keratin associated protein 10-2	keratin filament	Cellular component	-
TPR	7175	translocated promoter region, nuclear basket protein	negative regulation of RNA export from nucleus	Biological process	21613532
CTAGE5	4253	CTAGE family, member 5	protein binding	Molecular function	25416956
APEX1	328	APEX nuclease (multifunctional DNA repair enzyme) 1	transcription factor complex	Cellular component	-
SMAD4	4089	SMAD family member 4	DNA binding	Molecular function	9389648
ERI2	112479	ERI1 exoribonuclease family member 2	DNA catabolic process, exonucleolytic	Biological process	-
BMP10	27302	bone morphogenetic protein 10	SMAD protein signal transduction	Biological process	-
PTCHD4	442213	patched domain containing 4	hedgehog receptor activity	Molecular function	-
ARHGEF11	9826	Rho guanine nucleotide exchange factor (GEF) 11	cytokinesis	Biological process	10026210
UPP1	7378	uridine phosphorylase 1	nucleobase-containing small molecule metabolic process	Biological process	-
TCAP	8557	titin-cap	sarcomere organization	Biological process	17921333
HYAL1	3373	hyaluronoglucosaminidase 1	cellular response to pH	Biological process	19478093
QPCT	25797	glutaminyl-peptide cyclotransferase	cellular protein modification process	Biological process	7999256
LIG4	3981	ligase IV, DNA, ATP-dependent	DNA binding	Molecular function	8798671
KLRK1	22914	killer cell lectin-like receptor subfamily K, member 1	plasma membrane	Cellular component	-
ANGPT2	285	angiopoietin 2	glomerulus vasculature development	Biological process	-
UAP1	6675	UDP-N-acetylglucosamine pyrophosphorylase 1	protein N-linked glycosylation via asparagine	Biological process	-
NUDT2	318	nudix (nucleoside diphosphate linked moiety X)-type motif 2	nucleobase-containing compound metabolic process	Biological process	7487923
GSTM4	2948	glutathione S-transferase mu 4	protein binding	Molecular function	25416956
KCNA1	3736	potassium channel, voltage gated shaker related subfamily A, member 1	juxtaparanode region of axon	Cellular component	-
IFNA2	3440	interferon, alpha 2	defense response to virus	Biological process	22783022
SCP2	6342	sterol carrier protein 2	receptor binding	Molecular function	20178365
CAMK2B	816	calcium/calmodulin-dependent protein kinase II beta	positive regulation of synapse maturation	Biological process	-
T	6862	T, brachyury homolog (mouse)	somitogenesis	Biological process	-
TNF	7124	tumor necrosis factor	positive regulation of interleukin-8 biosynthetic process	Biological process	20551324
CYP2A6	1548	cytochrome P450, family 2, subfamily A, polypeptide 6	coumarin 7-hydroxylase activity	Molecular function	16086027
TNNI2	7136	troponin I type 2 (skeletal, fast)	muscle filament sliding	Biological process	-
CFAP46	54777	cilia and flagella associated protein 46	axoneme	Cellular component	-
GPER1	2852	G protein-coupled estrogen receptor 1	positive regulation of ERK1 and ERK2 cascade	Biological process	-
MRGPRE	116534	MAS-related GPR, member E	G-protein coupled receptor signaling pathway	Biological process	-
CYP1A1	1543	cytochrome P450, family 1, subfamily A, polypeptide 1	cellular lipid metabolic process	Biological process	-
SQSTM1	8878	sequestosome 1	PML body	Cellular component	20168092
NLRC3	197358	NLR family, CARD domain containing 3	molecular_function	Molecular function	-
SOX11	6664	SRY (sex determining region Y)-box 11	positive regulation of transcription, DNA-templated	Biological process	-
HAL	3034	histidine ammonia-lyase	small molecule metabolic process	Biological process	-
OR14I1	401994	olfactory receptor, family 14, subfamily I, member 1	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
DUSP4	1846	dual specificity phosphatase 4	protein tyrosine/serine/threonine phosphatase activity	Molecular function	-
LDLRAD4	753	low density lipoprotein receptor class A domain containing 4	early endosome membrane	Cellular component	-
PRKCE	5581	protein kinase C, epsilon	cytosol	Cellular component	-
HSPG2	3339	heparan sulfate proteoglycan 2	carbohydrate metabolic process	Biological process	-
RPS8	6202	ribosomal protein S8	cytoplasm	Cellular component	-
FMNL1	752	formin-like 1	extracellular exosome	Cellular component	20458337
SOX4	6659	SRY (sex determining region Y)-box 4	T cell differentiation	Biological process	-
NLRP3	114548	NLR family, pyrin domain containing 3	cellular response to lipopolysaccharide	Biological process	12483741
GIPC1	10755	GIPC PDZ domain containing family, member 1	protein homodimerization activity	Molecular function	-
EID3	493861	EP300 interacting inhibitor of differentiation 3	Smc5-Smc6 complex	Cellular component	18086888
GSTT2B	653689	glutathione S-transferase theta 2B (gene/pseudogene)	extracellular exosome	Cellular component	23533145
GNB1	2782	guanine nucleotide binding protein (G protein), beta polypeptide 1	cell body	Cellular component	-
POM121C	100101267	POM121 transmembrane nucleoporin C	protein transport	Biological process	-
CYB561D1	284613	cytochrome b561 family, member D1	integral component of membrane	Cellular component	-
AXIN2	8313	axin 2	negative regulation of cell proliferation	Biological process	16247484
ATP2C1	27032	ATPase, Ca++ transporting, type 2C, member 1	ATP binding	Molecular function	-
RPL4	6124	ribosomal protein L4	SRP-dependent cotranslational protein targeting to membrane	Biological process	-
CYP2J2	1573	cytochrome P450, family 2, subfamily J, polypeptide 2	icosanoid metabolic process	Biological process	8631948
CDC25A	993	cell division cycle 25A	protein binding	Molecular function	11298456
SMURF1	57154	SMAD specific E3 ubiquitin protein ligase 1	protein targeting to vacuole involved in autophagy	Biological process	22020285
GABRB2	2561	gamma-aminobutyric acid (GABA) A receptor, beta 2	synaptic transmission	Biological process	-
SGK3	23678	serum/glucocorticoid regulated kinase family, member 3	response to stress	Biological process	10548550
ACOX1	51	acyl-CoA oxidase 1, palmitoyl	nucleus	Cellular component	-
ADD2	119	adducin 2 (beta)	actin binding	Molecular function	1840603
MED14	9282	mediator complex subunit 14	ligand-dependent nuclear receptor transcription coactivator activity	Molecular function	10235266
CREB5	9586	cAMP responsive element binding protein 5	sequence-specific DNA binding	Molecular function	-
CEP350	9857	centrosomal protein 350kDa	nucleoplasm	Cellular component	-
CCR6	1235	chemokine (C-C motif) receptor 6	receptor activity	Molecular function	9186513
MLF1	4291	myeloid leukemia factor 1	protein binding	Molecular function	12176995
ISL1	3670	ISL LIM homeobox 1	neuron fate specification	Biological process	-
KRT1	3848	keratin 1, type II	plasma membrane	Cellular component	-
CYP26B1	56603	cytochrome P450, family 26, subfamily B, polypeptide 1	xenobiotic metabolic process	Biological process	-
KNDC1	85442	kinase non-catalytic C-lobe domain (KIND) containing 1	positive regulation of GTPase activity	Biological process	-
ALDH3A2	224	aldehyde dehydrogenase 3 family, member A2	endoplasmic reticulum membrane	Cellular component	-
IL2RG	3561	interleukin 2 receptor, gamma	integral component of plasma membrane	Cellular component	8514792
TCFL5	10732	transcription factor-like 5 (basic helix-loop-helix)	cell differentiation	Biological process	-
PEX1	5189	peroxisomal biogenesis factor 1	protein binding	Molecular function	16257970
CLK4	57396	CDC-like kinase 4	nucleus	Cellular component	-
SKP2	6502	S-phase kinase-associated protein 2, E3 ubiquitin protein ligase	regulation of apoptotic process	Biological process	23277542
NEUROG1	4762	neurogenin 1	inner ear morphogenesis	Biological process	-
ZNF513	130557	zinc finger protein 513	regulation of transcription, DNA-templated	Biological process	-
CSTA	1475	cystatin A (stefin A)	negative regulation of endopeptidase activity	Biological process	-
CXCL1	2919	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	inflammatory response	Biological process	-
SIRPG	55423	signal-regulatory protein gamma	plasma membrane	Cellular component	-
MCM7	4176	minichromosome maintenance complex component 7	DNA strand elongation involved in DNA replication	Biological process	-
HAGH	3029	hydroxyacylglutathione hydrolase	glutathione biosynthetic process	Biological process	8550579
CYP7B1	9420	cytochrome P450, family 7, subfamily B, polypeptide 1	bile acid biosynthetic process	Biological process	-
TNFSF14	8740	tumor necrosis factor (ligand) superfamily, member 14	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	12393901
PRDX1	5052	peroxiredoxin 1	removal of superoxide radicals	Biological process	-
NPC2	10577	Niemann-Pick disease, type C2	cholesterol efflux	Biological process	16141411
D2HGDH	728294	D-2-hydroxyglutarate dehydrogenase	oxidation-reduction process	Biological process	-
TBC1D20	128637	TBC1 domain family, member 20	virion assembly	Biological process	21680502
TMUB2	79089	transmembrane and ubiquitin-like domain containing 2	integral component of membrane	Cellular component	-
DIEXF	27042	digestive organ expansion factor homolog (zebrafish)	U3 snoRNA binding	Molecular function	-
UBA52	7311	ubiquitin A-52 residue ribosomal protein fusion product 1	Fc-epsilon receptor signaling pathway	Biological process	-
PLAU	5328	plasminogen activator, urokinase	regulation of smooth muscle cell migration	Biological process	8837777
SMG7	9887	SMG7 nonsense mediated mRNA decay factor	cytoplasm	Cellular component	-
CRELD2	79174	cysteine-rich with EGF-like domains 2	endoplasmic reticulum	Cellular component	-
EPHB3	2049	EPH receptor B3	corpus callosum development	Biological process	-
NTS	4922	neurotensin	transport vesicle	Cellular component	-
METTL23	124512	methyltransferase like 23	integral component of membrane	Cellular component	-
NFKB1	4790	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	response to oxidative stress	Biological process	-
TMTC2	160335	transmembrane and tetratricopeptide repeat containing 2	endoplasmic reticulum membrane	Cellular component	24764305
RIPK4	54101	receptor-interacting serine-threonine kinase 4	membrane	Cellular component	-
OR56A4	120793	olfactory receptor, family 56, subfamily A, member 4	olfactory receptor activity	Molecular function	-
UROS	7390	uroporphyrinogen III synthase	porphyrin-containing compound metabolic process	Biological process	-
SCNM1	79005	sodium channel modifier 1	enzyme binding	Molecular function	23382074
BCAT1	586	branched chain amino-acid transaminase 1, cytosolic	L-isoleucine transaminase activity	Molecular function	-
VRTN	55237	vertebrae development associated	transposase activity	Molecular function	-
RASGEF1A	221002	RasGEF domain family, member 1A	small GTPase mediated signal transduction	Biological process	-
IGF1	3479	insulin-like growth factor 1 (somatomedin C)	negative regulation of release of cytochrome c from mitochondria	Biological process	-
KCNJ11	3767	potassium channel, inwardly rectifying subfamily J, member 11	intercalated disc	Cellular component	-
FGB	2244	fibrinogen beta chain	blood microparticle	Cellular component	22516433
WDFY1	57590	WD repeat and FYVE domain containing 1	nucleus	Cellular component	11739631
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	innate immune response	Biological process	-
CYP3A5	1577	cytochrome P450, family 3, subfamily A, polypeptide 5	drug catabolic process	Biological process	15039299
PMPCA	23203	peptidase (mitochondrial processing) alpha	protein targeting to mitochondrion	Biological process	-
KCNS3	3790	potassium voltage-gated channel, modifier subfamily S, member 3	synaptic transmission	Biological process	-
SP2	6668	Sp2 transcription factor	regulation of transcription from RNA polymerase II promoter	Biological process	1341900
ZNF451	26036	zinc finger protein 451	regulation of transcription, DNA-templated	Biological process	-
SPARC	6678	secreted protein, acidic, cysteine-rich (osteonectin)	ossification	Biological process	-
COCH	1690	cochlin	protein binding	Molecular function	21886777
PSMG1	8624	proteasome (prosome, macropain) assembly chaperone 1	cerebellar granule cell precursor proliferation	Biological process	-
CIPC	85457	CLOCK-interacting pacemaker	transcription, DNA-templated	Biological process	-
METTL17	64745	methyltransferase like 17	nucleoplasm	Cellular component	-
UBB	7314	ubiquitin B	stress-activated MAPK cascade	Biological process	-
UBE2E3	10477	ubiquitin-conjugating enzyme E2E 3	ubiquitin-protein transferase activity	Molecular function	20061386
OTOP3	347741	otopetrin 3	integral component of membrane	Cellular component	-
NR5A1	2516	nuclear receptor subfamily 5, group A, member 1	sequence-specific DNA binding	Molecular function	-
BMP2	650	bone morphogenetic protein 2	activation of MAPK activity	Biological process	17202865
CLECL1	160365	C-type lectin-like 1	integral component of membrane	Cellular component	-
SLC9A3R2	9351	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2	protein binding	Molecular function	11285285
ICK	22858	intestinal cell (MAK-like) kinase	nucleus	Cellular component	-
DDX3Y	8653	DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked	RNA secondary structure unwinding	Biological process	-
CDC42	998	cell division cycle 42	cytosol	Cellular component	-
MARK1	4139	MAP/microtubule affinity-regulating kinase 1	cytoplasm	Cellular component	-
PRKAA1	5562	protein kinase, AMP-activated, alpha 1 catalytic subunit	rhythmic process	Biological process	-
EYA3	2140	EYA transcriptional coactivator and phosphatase 3	anatomical structure morphogenesis	Biological process	9020840
TGM2	7052	transglutaminase 2	protein binding	Molecular function	16301118
RHOT1	55288	ras homolog family member T1	integral component of mitochondrial outer membrane	Cellular component	12482879
MYC	4609	v-myc avian myelocytomatosis viral oncogene homolog	positive regulation of mesenchymal cell proliferation	Biological process	-
STUB1	10273	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase	misfolded protein binding	Molecular function	16831871
PSMD4	5710	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	programmed cell death	Biological process	-
PAK1	5058	p21 protein (Cdc42/Rac)-activated kinase 1	positive regulation of peptidyl-serine phosphorylation	Biological process	19667065
UBA7	7318	ubiquitin-like modifier activating enzyme 7	protein binding	Molecular function	16189514
ARF3	377	ADP-ribosylation factor 3	phosphatidylinositol biosynthetic process	Biological process	-
CXCR1	3577	chemokine (C-X-C motif) receptor 1	interleukin-8 binding	Molecular function	11564821
NDUFS1	4719	NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)	cellular respiration	Biological process	15186778
CLEC2B	9976	C-type lectin domain family 2, member B	carbohydrate binding	Molecular function	-
SBDS	51119	Shwachman-Bodian-Diamond syndrome	leukocyte chemotaxis	Biological process	14743349
TRPV4	59341	transient receptor potential cation channel, subfamily V, member 4	positive regulation of cytosolic calcium ion concentration	Biological process	18458941
ATIC	471	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	extracellular exosome	Cellular component	19056867
PARK2	5071	parkin RBR E3 ubiquitin protein ligase	ubiquitin conjugating enzyme binding	Molecular function	11439185
HIST1H3I	8354	histone cluster 1, H3i	nucleosome assembly	Biological process	25615412
SIX5	147912	SIX homeobox 5	cytoplasm	Cellular component	-
BLOC1S6	26258	biogenesis of lysosomal organelles complex-1, subunit 6, pallidin	membrane fusion	Biological process	-
AGAP1	116987	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1	phospholipid binding	Molecular function	18954304
EIF2AK2	5610	eukaryotic translation initiation factor 2-alpha kinase 2	protein autophosphorylation	Biological process	16216244
NTRK1	4914	neurotrophic tyrosine kinase, receptor, type 1	positive regulation of Ras protein signal transduction	Biological process	15488758
SRF	6722	serum response factor (c-fos serum response element-binding transcription factor)	muscle cell cellular homeostasis	Biological process	-
SLC2A4	6517	solute carrier family 2 (facilitated glucose transporter), member 4	hexose transmembrane transport	Biological process	-
KLHL10	317719	kelch-like family member 10	Cul3-RING ubiquitin ligase complex	Cellular component	-
JAK2	3717	Janus kinase 2	heme binding	Molecular function	21036157
FOXO4	4303	forkhead box O4	cytosol	Cellular component	22972301
CASP3	836	caspase 3, apoptosis-related cysteine peptidase	heart development	Biological process	-
ARNTL	406	aryl hydrocarbon receptor nuclear translocator-like	regulation of type B pancreatic cell development	Biological process	-
PLCB3	5331	phospholipase C, beta 3 (phosphatidylinositol-specific)	calmodulin binding	Molecular function	12821674
CD44	960	CD44 molecule (Indian blood group)	cell surface	Cellular component	16809613
TNNC1	7134	troponin C type 1 (slow)	actin cytoskeleton	Cellular component	-
CYTH1	9267	cytohesin 1	regulation of cell adhesion	Biological process	12606567
POU6F2	11281	POU class 6 homeobox 2	transcription from RNA polymerase II promoter	Biological process	8601806
PLA2G4A	5321	phospholipase A2, group IVA (cytosolic, calcium-dependent)	arachidonic acid metabolic process	Biological process	-
TRAF2	7186	TNF receptor-associated factor 2	cell cortex	Cellular component	-
ZBTB49	166793	zinc finger and BTB domain containing 49	cytoplasm	Cellular component	25245946
INPP5K	51763	inositol polyphosphate-5-phosphatase K	negative regulation of transcription, DNA-templated	Biological process	-
KRTAP10-12	386685	keratin associated protein 10-12	keratin filament	Cellular component	-
SLC36A2	153201	solute carrier family 36 (proton/amino acid symporter), member 2	hydrogen:amino acid symporter activity	Molecular function	-
OIT3	170392	oncoprotein induced transcript 3	calcium ion binding	Molecular function	-
UBA52	7311	ubiquitin A-52 residue ribosomal protein fusion product 1	transmembrane transport	Biological process	-
IQGAP3	128239	IQ motif containing GTPase activating protein 3	small GTPase mediated signal transduction	Biological process	-
TUBA3E	112714	tubulin, alpha 3e	biological_process	Biological process	-
DMBX1	127343	diencephalon/mesencephalon homeobox 1	negative regulation of transcription, DNA-templated	Biological process	-
SLC26A4	5172	solute carrier family 26 (anion exchanger), member 4	integral component of membrane	Cellular component	-
NKRF	55922	NFKB repressing factor	endoplasmic reticulum	Cellular component	-
S100B	6285	S100 calcium binding protein B	regulation of cell shape	Biological process	-
CRH	1392	corticotropin releasing hormone	positive regulation of cell proliferation	Biological process	-
BMPR1A	657	bone morphogenetic protein receptor, type IA	pituitary gland development	Biological process	-
SLC24A2	25769	solute carrier family 24 (sodium/potassium/calcium exchanger), member 2	calcium channel activity	Molecular function	-
BIRC6	57448	baculoviral IAP repeat containing 6	positive regulation of cell proliferation	Biological process	-
MAPK10	5602	mitogen-activated protein kinase 10	innate immune response	Biological process	-
ZNF318	24149	zinc finger protein 318	nucleoplasm	Cellular component	-
DMRT1	1761	doublesex and mab-3 related transcription factor 1	sequence-specific DNA binding transcription factor activity	Molecular function	-
MRPL54	116541	mitochondrial ribosomal protein L54	mitochondrial inner membrane	Cellular component	-
SLC51B	123264	solute carrier family 51, beta subunit	protein complex	Cellular component	-
BRF1	2972	BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit	gene expression	Biological process	-
ORC2	4999	origin recognition complex, subunit 2	membrane	Cellular component	19946888
HRH2	3274	histamine receptor H2	synaptic transmission, dopaminergic	Biological process	-
ACER2	340485	alkaline ceramidase 2	dihydroceramidase activity	Molecular function	20628055
VPS54	51542	vacuolar protein sorting 54 homolog (S. cerevisiae)	protein binding	Molecular function	15878329
OR2G6	391211	olfactory receptor, family 2, subfamily G, member 6	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
MAPT	4137	microtubule-associated protein tau	nuclear periphery	Cellular component	19157893
USP7	7874	ubiquitin specific peptidase 7 (herpes virus-associated)	transcription factor binding	Molecular function	16964248
SYNE1	23345	spectrin repeat containing, nuclear envelope 1	cytoskeleton	Cellular component	-
PDE6A	5145	phosphodiesterase 6A, cGMP-specific, rod, alpha	visual perception	Biological process	-
CALCA	796	calcitonin-related polypeptide alpha	hormone activity	Molecular function	-
CD36	948	CD36 molecule (thrombospondin receptor)	transforming growth factor beta binding	Molecular function	-
FAR2P1	440905	fatty acyl CoA reductase 2 pseudogene 1	fatty-acyl-CoA reductase (alcohol-forming) activity	Molecular function	-
PARK7	11315	parkinson protein 7	membrane depolarization	Biological process	-
COL7A1	1294	collagen, type VII, alpha 1	endodermal cell differentiation	Biological process	23154389
BCL2	596	B-cell CLL/lymphoma 2	humoral immune response	Biological process	1908951
SPSB1	80176	splA/ryanodine receptor domain and SOCS box containing 1	protein ubiquitination	Biological process	-
Sep-07	989	septin 7	identical protein binding	Molecular function	22064074
SMPD2	6610	sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)	caveola	Cellular component	-
CHEK1	1111	checkpoint kinase 1	condensed nuclear chromosome	Cellular component	9382850
MRPL12	6182	mitochondrial ribosomal protein L12	mitochondrial inner membrane	Cellular component	-
DUSP15	128853	dual specificity phosphatase 15	plasma membrane	Cellular component	-
AMMECR1	9949	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	molecular_function	Molecular function	-
SNX33	257364	sorting nexin 33	identical protein binding	Molecular function	19487689
HMGA1	3159	high mobility group AT-hook 1	retinoid X receptor binding	Molecular function	10428834
PSMB10	5699	proteasome (prosome, macropain) subunit, beta type, 10	regulation of apoptotic process	Biological process	-
PRTN3	5657	proteinase 3	extracellular space	Cellular component	16502470
DAP3	7818	death associated protein 3	mitochondrial translational elongation	Biological process	-
RDH8	50700	retinol dehydrogenase 8 (all-trans)	retinoid metabolic process	Biological process	-
DNAJC19	131118	DnaJ (Hsp40) homolog, subfamily C, member 19	protein targeting to mitochondrion	Biological process	-
IFNA2	3440	interferon, alpha 2	negative regulation of gene expression	Biological process	20554961
CXCL13	10563	chemokine (C-X-C motif) ligand 13	lymph node development	Biological process	-
ZNF251	90987	zinc finger protein 251	regulation of transcription, DNA-templated	Biological process	-
SAE1	10055	SUMO1 activating enzyme subunit 1	ubiquitin activating enzyme activity	Molecular function	10187858
GRK5	2869	G protein-coupled receptor kinase 5	beta-adrenergic receptor kinase activity	Molecular function	20038610
NOL3	8996	nucleolar protein 3 (apoptosis repressor with CARD domain)	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	Biological process	15004034
DDX54	79039	DEAD (Asp-Glu-Ala-Asp) box polypeptide 54	regulation of transcription, DNA-templated	Biological process	-
OR2T33	391195	olfactory receptor, family 2, subfamily T, member 33	sensory perception of smell	Biological process	-
UBB	7314	ubiquitin B	extracellular exosome	Cellular component	23533145
NTSR2	23620	neurotensin receptor 2	integral component of plasma membrane	Cellular component	9851594
PIFO	128344	primary cilia formation	kinesin binding	Molecular function	20643351
ARL13B	200894	ADP-ribosylation factor-like 13B	cilium	Cellular component	-
CDK19	23097	cyclin-dependent kinase 19	protein phosphorylation	Biological process	-
ITGA3	3675	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	dendritic spine maintenance	Biological process	-
ACTC1	70	actin, alpha, cardiac muscle 1	apoptotic process	Biological process	-
UTS2R	2837	urotensin 2 receptor	recycling endosome	Cellular component	-
ORC1	4998	origin recognition complex, subunit 1	G1/S transition of mitotic cell cycle	Biological process	-
KRTAP2-1	81872	keratin associated protein 2-1	keratin filament	Cellular component	-
CNDP2	55748	CNDP dipeptidase 2 (metallopeptidase M20 family)	cellular nitrogen compound metabolic process	Biological process	-
MUC3A	4584	mucin 3A, cell surface associated	O-glycan processing	Biological process	-
UBXN6	80700	UBX domain protein 6	microtubule organizing center	Cellular component	-
ATP2B4	493	ATPase, Ca++ transporting, plasma membrane 4	negative regulation of peptidyl-cysteine S-nitrosylation	Biological process	18591664
ATP2A2	488	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	S100 protein binding	Molecular function	12804600
FOXP3	50943	forkhead box P3	negative regulation of CREB transcription factor activity	Biological process	16652169
AP1M2	10053	adaptor-related protein complex 1, mu 2 subunit	cytoplasmic vesicle membrane	Cellular component	-
TOP1	7150	topoisomerase (DNA) I	core promoter sequence-specific DNA binding	Molecular function	22904072
PTK2B	2185	protein tyrosine kinase 2 beta	positive regulation of synaptic transmission, glutamatergic	Biological process	-
RIMS2	9699	regulating synaptic membrane exocytosis 2	metal ion binding	Molecular function	-
TGS1	96764	trimethylguanosine synthase 1	small nuclear ribonucleoprotein complex	Cellular component	16687569
RPS6	6194	ribosomal protein S6	rRNA processing	Biological process	18697920
HTR3B	9177	5-hydroxytryptamine (serotonin) receptor 3B, ionotropic	synaptic transmission	Biological process	9950429
NFKBIA	4792	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	Fc-epsilon receptor signaling pathway	Biological process	-
GIPR	2696	gastric inhibitory polypeptide receptor	peptide hormone binding	Molecular function	-
CIB2	10518	calcium and integrin binding family member 2	blood microparticle	Cellular component	22516433
FOXO4	4303	forkhead box O4	innate immune response	Biological process	-
CLPX	10845	caseinolytic mitochondrial matrix peptidase chaperone subunit	mitochondrial nucleoid	Cellular component	18063578
FREM1	158326	FRAS1 related extracellular matrix 1	craniofacial suture morphogenesis	Biological process	21931569
ATP6V1B1	525	ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1	ossification	Biological process	16433694
BMX	660	BMX non-receptor tyrosine kinase	peptidyl-tyrosine autophosphorylation	Biological process	-
CTSG	1511	cathepsin G	neutrophil mediated killing of gram-positive bacterium	Biological process	-
VCL	7414	vinculin	negative regulation of cell migration	Biological process	15494027
USP50	373509	ubiquitin specific peptidase 50	ubiquitin-specific protease activity	Molecular function	-
LARS	51520	leucyl-tRNA synthetase	regulation of translational fidelity	Biological process	-
MTNR1B	4544	melatonin receptor 1B	integral component of plasma membrane	Cellular component	7568007
ACP5	54	acid phosphatase 5, tartrate resistant	bone morphogenesis	Biological process	-
SEL1L	6400	sel-1 suppressor of lin-12-like (C. elegans)	Hrd1p ubiquitin ligase complex	Cellular component	23710284
CRHR1	1394	corticotropin releasing hormone receptor 1	cellular response to corticotropin-releasing hormone stimulus	Biological process	18292205
PTCD1	26024	pentatricopeptide repeat domain 1	mitochondrion	Cellular component	19651879
CISH	1154	cytokine inducible SH2-containing protein	cytokine-mediated signaling pathway	Biological process	-
PIK3C2B	5287	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta	inflammatory response	Biological process	-
GLT1D1	144423	glycosyltransferase 1 domain containing 1	cytoplasm	Cellular component	-
GDF11	10220	growth differentiation factor 11	transforming growth factor beta receptor binding	Molecular function	-
FYN	2534	FYN proto-oncogene, Src family tyrosine kinase	growth factor receptor binding	Molecular function	16479011
CNTNAP2	26047	contactin associated protein-like 2	cell adhesion	Biological process	-
C7orf73	647087	chromosome 7 open reading frame 73	mitochondrial membrane	Cellular component	-
MEOX1	4222	mesenchyme homeobox 1	sequence-specific DNA binding transcription factor activity	Molecular function	-
ZRANB3	84083	zinc finger, RAN-binding domain containing 3	negative regulation of DNA recombination	Biological process	22704558
NME1	4830	NME/NM23 nucleoside diphosphate kinase 1	nucleoside diphosphate kinase activity	Molecular function	12972261
ANAPC11	51529	anaphase promoting complex subunit 11	mitotic spindle assembly checkpoint	Biological process	-
GLA	2717	galactosidase, alpha	negative regulation of nitric-oxide synthase activity	Biological process	-
ADCY7	113	adenylate cyclase 7	transmembrane transport	Biological process	-
RNF168	165918	ring finger protein 168, E3 ubiquitin protein ligase	cellular protein metabolic process	Biological process	-
ANG	283	angiogenin, ribonuclease, RNase A family, 5	growth cone	Cellular component	-
MEGF10	84466	multiple EGF-like-domains 10	phagocytic cup	Cellular component	-
SLC38A2	54407	solute carrier family 38, member 2	amino acid transmembrane transporter activity	Molecular function	-
MSMO1	6307	methylsterol monooxygenase 1	small molecule metabolic process	Biological process	-
KIF23	9493	kinesin family member 23	mitotic cytokinesis	Biological process	15843429
MGEA5	10724	meningioma expressed antigen 5 (hyaluronidase)	positive regulation of proteolysis	Biological process	-
TTLL5	23093	tubulin tyrosine ligase-like family member 5	cytoplasm	Cellular component	-
WNT9B	7484	wingless-type MMTV integration site family, member 9B	branching involved in ureteric bud morphogenesis	Biological process	-
GCC2	9648	GRIP and coiled-coil domain containing 2	microtubule organizing center organization	Biological process	17543864
TXLNG	55787	taxilin gamma	cell cycle	Biological process	-
S100A1	6271	S100 calcium binding protein A1	M band	Cellular component	-
PSD2	84249	pleckstrin and Sec7 domain containing 2	vesicle-mediated transport	Biological process	-
SLC5A6	8884	solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6	transmembrane transport	Biological process	-
TAS2R1	50834	taste receptor, type 2, member 1	chemosensory behavior	Biological process	10761934
NODAL	4838	nodal growth differentiation factor	morphogen activity	Molecular function	21159651
SH3BGRL3	83442	SH3 domain binding glutamate-rich protein like 3	protein disulfide oxidoreductase activity	Molecular function	-
RAMP2	10266	receptor (G protein-coupled) activity modifying protein 2	sprouting angiogenesis	Biological process	-
MBD2	8932	methyl-CpG binding domain protein 2	ATP-dependent chromatin remodeling	Biological process	16217013
NODAL	4838	nodal growth differentiation factor	placenta development	Biological process	21356369
GTF2H1	2965	general transcription factor IIH, polypeptide 1, 62kDa	gene expression	Biological process	-
CDK5R1	8851	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	rhythmic process	Biological process	-
FAM168B	130074	family with sequence similarity 168, member B	plasma membrane	Cellular component	-
AP2A2	161	adaptor-related protein complex 2, alpha 2 subunit	clathrin-coated endocytic vesicle membrane	Cellular component	-
TBCD	6904	tubulin folding cofactor D	negative regulation of microtubule polymerization	Biological process	10831612
RAB10	10890	RAB10, member RAS oncogene family	GDP binding	Molecular function	20937701
CD86	942	CD86 molecule	epidermal growth factor receptor signaling pathway	Biological process	-
PPP1R3F	89801	protein phosphatase 1, regulatory subunit 3F	regulation of glycogen biosynthetic process	Biological process	21668450
PKD2	5311	polycystic kidney disease 2 (autosomal dominant)	regulation of calcium ion import	Biological process	11854751
H3F3C	440093	H3 histone, family 3C	protein heterodimerization activity	Molecular function	-
ACVR1	90	activin A receptor, type I	regulation of ossification	Biological process	16642017
RAB14	51552	RAB14, member RAS oncogene family	protein binding	Molecular function	16034420
HSPB1	3315	heat shock 27kDa protein 1	protein kinase binding	Molecular function	8774846
MID2	11043	midline 2	zinc ion binding	Molecular function	-
GLRA4	441509	glycine receptor, alpha 4	cell junction	Cellular component	-
TRAF2	7186	TNF receptor-associated factor 2	innate immune response	Biological process	-
NKX3-1	4824	NK3 homeobox 1	positive regulation of response to DNA damage stimulus	Biological process	20395202
IFIT1	3434	interferon-induced protein with tetratricopeptide repeats 1	cellular response to type I interferon	Biological process	19008854
RAPSN	5913	receptor-associated protein of the synapse	cytoplasm	Cellular component	-
PSEN2	5664	presenilin 2	Golgi apparatus	Cellular component	15274632
UGT3A1	133688	UDP glycosyltransferase 3 family, polypeptide A1	flavonoid biosynthetic process	Biological process	-
RNF138	51444	ring finger protein 138, E3 ubiquitin protein ligase	protein binding	Molecular function	19549727
TYSND1	219743	trypsin domain containing 1	proteolysis	Biological process	22002062
SRRM2	23524	serine/arginine repetitive matrix 2	Cajal body	Cellular component	17577209
SRSF9	8683	serine/arginine-rich splicing factor 9	transcription from RNA polymerase II promoter	Biological process	-
APP	351	amyloid beta (A4) precursor protein	platelet alpha granule lumen	Cellular component	-
POLQ	10721	polymerase (DNA directed), theta	nucleoplasm	Cellular component	10395804
PGR	5241	progesterone receptor	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	17785366
DPP8	54878	dipeptidyl-peptidase 8	membrane	Cellular component	-
ZSCAN25	221785	zinc finger and SCAN domain containing 25	transcription, DNA-templated	Biological process	-
SMAD4	4089	SMAD family member 4	SMAD protein signal transduction	Biological process	9707553
TLR4	7099	toll-like receptor 4	positive regulation of JNK cascade	Biological process	-
HOPX	84525	HOP homeobox	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
ERCC5	2073	excision repair cross-complementation group 5	UV protection	Biological process	7510366
SALL2	6297	spalt-like transcription factor 2	protein binding	Molecular function	16189514
HECW2	57520	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2	ubiquitin-protein transferase activity	Molecular function	-
FOXA1	3169	forkhead box A1	nucleus	Cellular component	-
SLC7A4	6545	solute carrier family 7, member 4	L-ornithine transmembrane transporter activity	Molecular function	-
ZNF347	84671	zinc finger protein 347	DNA binding	Molecular function	-
COL15A1	1306	collagen, type XV, alpha 1	collagen catabolic process	Biological process	-
NFKBIL1	4795	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1	negative regulation of NF-kappaB transcription factor activity	Biological process	20829348
PVRIG	79037	poliovirus receptor related immunoglobulin domain containing	integral component of membrane	Cellular component	-
ING3	54556	inhibitor of growth family, member 3	chromatin organization	Biological process	-
TXN	7295	thioredoxin	cell redox homeostasis	Biological process	-
PCCA	5095	propionyl CoA carboxylase, alpha polypeptide	mitochondrial matrix	Cellular component	-
DNAI1	27019	dynein, axonemal, intermediate chain 1	microtubule	Cellular component	-
FOXC1	2296	forkhead box C1	sequence-specific DNA binding RNA polymerase II transcription factor activity	Molecular function	-
EDNRB	1910	endothelin receptor type B	cytosol	Cellular component	-
APOBEC3G	60489	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G	innate immune response	Biological process	17121840
MPST	4357	mercaptopyruvate sulfurtransferase	thiosulfate sulfurtransferase activity	Molecular function	-
KRT25	147183	keratin 25, type I	hair cycle	Biological process	21916889
WDR5	11091	WD repeat domain 5	Ada2/Gcn5/Ada3 transcription activator complex	Cellular component	18838386
Mar-01	55016	membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase	endosome	Cellular component	14722266
CDYL	9425	chromodomain protein, Y-like	methylated histone binding	Molecular function	18450745
CDK5RAP3	80279	CDK5 regulatory subunit associated protein 3	negative regulation of NF-kappaB transcription factor activity	Biological process	17785205
CIRH1A	84916	cirrhosis, autosomal recessive 1A (cirhin)	maturation of SSU-rRNA	Biological process	22916032
RHOA	387	ras homolog family member A	regulation of small GTPase mediated signal transduction	Biological process	-
GBA2	57704	glucosidase, beta (bile acid) 2	glucosylceramidase activity	Molecular function	-
GABRA6	2559	gamma-aminobutyric acid (GABA) A receptor, alpha 6	transport	Biological process	8632757
ACOT2	10965	acyl-CoA thioesterase 2	acyl-CoA metabolic process	Biological process	10944470
EIF2AK2	5610	eukaryotic translation initiation factor 2-alpha kinase 2	innate immune response	Biological process	-
PSAP	5660	prosaposin	extracellular exosome	Cellular component	19056867
TUBB6	84617	tubulin, beta 6 class V	extracellular exosome	Cellular component	19056867
MGARP	84709	mitochondria-localized glutamic acid-rich protein	mitochondrion	Cellular component	16565373
CACNB1	782	calcium channel, voltage-dependent, beta 1 subunit	axon guidance	Biological process	-
ITPKC	80271	inositol-trisphosphate 3-kinase C	calmodulin binding	Molecular function	-
VTI1A	143187	vesicle transport through interaction with t-SNAREs 1A	retrograde transport, endosome to Golgi	Biological process	19224922
FOXP3	50943	forkhead box P3	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity	Molecular function	-
AOX1	316	aldehyde oxidase 1	vitamin metabolic process	Biological process	-
ITCH	83737	itchy E3 ubiquitin protein ligase	positive regulation of T cell anergy	Biological process	-
FANCI	55215	Fanconi anemia, complementation group I	cytoplasm	Cellular component	-
PF4	5196	platelet factor 4	response to lipopolysaccharide	Biological process	-
IKBKG	8517	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	mitotic spindle	Cellular component	24561039
ATP2A3	489	ATPase, Ca++ transporting, ubiquitous	sarcoplasmic reticulum	Cellular component	8809064
CLN3	1201	ceroid-lipofuscinosis, neuronal 3	nucleus	Cellular component	10191116
NOTCH4	4855	notch 4	receptor activity	Molecular function	11823422
ABCA1	19	ATP-binding cassette, sub-family A (ABC1), member 1	receptor binding	Molecular function	23931754
SORL1	6653	sortilin-related receptor, L(DLR class) A repeats containing	negative regulation of protein binding	Biological process	16407538
WNT5A	7474	wingless-type MMTV integration site family, member 5A	urinary bladder development	Biological process	-
NONO	4841	non-POU domain containing, octamer-binding	mRNA processing	Biological process	-
WDR62	284403	WD repeat domain 62	cytoplasm	Cellular component	-
PIAS4	51588	protein inhibitor of activated STAT, 4	post-translational protein modification	Biological process	-
KIAA1598	57698	KIAA1598	axon guidance	Biological process	-
FERMT2	10979	fermitin family member 2	cell junction assembly	Biological process	-
TNFRSF17	608	tumor necrosis factor receptor superfamily, member 17	integral component of membrane	Cellular component	-
NUMA1	4926	nuclear mitotic apparatus protein 1	nucleoplasm	Cellular component	-
KCTD4	386618	potassium channel tetramerization domain containing 4	protein homooligomerization	Biological process	-
TP53	7157	tumor protein p53	T cell proliferation involved in immune response	Biological process	-
RAB40C	57799	RAB40C, member RAS oncogene family	intracellular protein transport	Biological process	-
PES1	23481	pescadillo ribosomal biogenesis factor 1	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Biological process	16738141
RNF183	138065	ring finger protein 183	zinc ion binding	Molecular function	-
SYT7	9066	synaptotagmin VII	integral component of membrane	Cellular component	-
APOB	338	apolipoprotein B	positive regulation of lipid storage	Biological process	18322245
KIF20A	10112	kinesin family member 20A	ATPase activity	Molecular function	-
HIPK1	204851	homeodomain interacting protein kinase 1	cytoplasm	Cellular component	15701637
JCHAIN	3512	joining chain of multimeric IgA and IgM	secretory IgA immunoglobulin complex	Cellular component	23250751
SLFN12L	100506736	schlafen family member 12-like	integral component of membrane	Cellular component	-
BRCA2	675	breast cancer 2, early onset	spermatogenesis	Biological process	-
STX1A	6804	syntaxin 1A (brain)	regulation of insulin secretion	Biological process	15537656
MAPK1	5594	mitogen-activated protein kinase 1	regulation of early endosome to late endosome transport	Biological process	19565474
SMAD3	4088	SMAD family member 3	lens fiber cell differentiation	Biological process	-
SCAMP5	192683	secretory carrier membrane protein 5	protein transport	Biological process	-
TYR	7299	tyrosinase	oxidation-reduction process	Biological process	-
OR4C5	79346	olfactory receptor, family 4, subfamily C, member 5 (gene/pseudogene)	detection of chemical stimulus involved in sensory perception	Biological process	-
ARSG	22901	arylsulfatase G	arylsulfatase activity	Molecular function	16174644
ATXN8	724066	ataxin 8	nucleus	Cellular component	-
MAP2K5	5607	mitogen-activated protein kinase kinase 5	intracellular	Cellular component	-
ALOX15B	247	arachidonate 15-lipoxygenase, type B	negative regulation of cell proliferation	Biological process	12704195
HMGA1	3159	high mobility group AT-hook 1	transcription, DNA-templated	Biological process	-
ZP3	7784	zona pellucida glycoprotein 3 (sperm receptor)	intracellular signal transduction	Biological process	18667750
TINAGL1	64129	tubulointerstitial nephritis antigen-like 1	protein binding	Molecular function	25416956
FMR1	2332	fragile X mental retardation 1	dendritic spine	Cellular component	-
TAF3	83860	TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa	maintenance of protein location in nucleus	Biological process	15870280
KIF11	3832	kinesin family member 11	ATP-dependent microtubule motor activity, plus-end-directed	Molecular function	-
POLD4	57804	polymerase (DNA-directed), delta 4, accessory subunit	DNA repair	Biological process	-
ARHGAP8	23779	Rho GTPase activating protein 8	positive regulation of GTPase activity	Biological process	-
KLF4	9314	Kruppel-like factor 4 (gut)	post-embryonic camera-type eye development	Biological process	-
HSPA1B	3304	heat shock 70kDa protein 1B	positive regulation of IRE1-mediated unfolded protein response	Biological process	20625543
CAV1	857	caveolin 1, caveolae protein, 22kDa	patched binding	Molecular function	11278759
ARAP1	116985	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1	metal ion binding	Molecular function	-
CELF3	11189	CUGBP, Elav-like family member 3	cytoplasm	Cellular component	17725984
PLCB1	23236	phospholipase C, beta 1 (phosphoinositide-specific)	positive regulation of myoblast differentiation	Biological process	-
EDNRA	1909	endothelin receptor type A	penile erection	Biological process	-
UTP20	27340	UTP20, small subunit (SSU) processome component, homolog (yeast)	nucleolus	Cellular component	15590835
PTGES3	10728	prostaglandin E synthase 3 (cytosolic)	prostaglandin-E synthase activity	Molecular function	10922363
OR5M1	390168	olfactory receptor, family 5, subfamily M, member 1	integral component of plasma membrane	Cellular component	-
TOP2A	7153	topoisomerase (DNA) II alpha 170kDa	condensed chromosome	Cellular component	-
OSGEPL1	64172	O-sialoglycoprotein endopeptidase-like 1	threonylcarbamoyladenosine biosynthetic process	Biological process	-
RBM39	9584	RNA binding motif protein 39	poly(A) RNA binding	Molecular function	22658674
NPC1	4864	Niemann-Pick disease, type C1	cholesterol homeostasis	Biological process	-
SLC35F1	222553	solute carrier family 35, member F1	integral component of membrane	Cellular component	-
CA3	761	carbonic anhydrase III	response to oxidative stress	Biological process	-
ASTL	431705	astacin-like metallo-endopeptidase (M12 family)	metalloendopeptidase activity	Molecular function	15087446
TROVE2	6738	TROVE domain family, member 2	ribonucleoprotein complex	Cellular component	17289661
FADS3	3995	fatty acid desaturase 3	molecular_function	Molecular function	-
SETD1A	9739	SET domain containing 1A	nucleus	Cellular component	22723415
ASS1	445	argininosuccinate synthase 1	midgut development	Biological process	-
PSEN1	5663	presenilin 1	neuronal cell body	Cellular component	-
CADM1	23705	cell adhesion molecule 1	synapse assembly	Biological process	-
STX8	9482	syntaxin 8	protein binding	Molecular function	25416956
SEC61B	10952	Sec61 beta subunit	membrane	Cellular component	22375059
OR52A5	390054	olfactory receptor, family 52, subfamily A, member 5	plasma membrane	Cellular component	-
PCDH11Y	83259	protocadherin 11 Y-linked	homophilic cell adhesion via plasma membrane adhesion molecules	Biological process	-
TREML1	340205	triggering receptor expressed on myeloid cells-like 1	platelet alpha granule	Cellular component	-
RPL22	6146	ribosomal protein L22	nucleus	Cellular component	22720776
PNLIP	5406	pancreatic lipase	positive regulation of triglyceride lipase activity	Biological process	9631512
OSR1	130497	odd-skipped related transciption factor 1	transcription, DNA-templated	Biological process	-
ARHGAP26	23092	Rho GTPase activating protein 26	regulation of small GTPase mediated signal transduction	Biological process	-
IDS	3423	iduronate 2-sulfatase	small molecule metabolic process	Biological process	-
CHGA	1113	chromogranin A	secretory granule	Cellular component	-
DAG1	1605	dystroglycan 1 (dystrophin-associated glycoprotein 1)	contractile ring	Cellular component	18341635
CLU	1191	clusterin	microglial cell proliferation	Biological process	15857407
LPAL2	80350	lipoprotein, Lp(a)-like 2, pseudogene	extracellular region	Cellular component	-
SORL1	6653	sortilin-related receptor, L(DLR class) A repeats containing	protein binding	Molecular function	14764453
ERN1	2081	endoplasmic reticulum to nucleus signaling 1	regulation of transcription, DNA-templated	Biological process	-
HACE1	57531	HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1	cell cycle	Biological process	-
EDN1	1906	endothelin 1	cellular response to fatty acid	Biological process	-
SPRTN	83932	SprT-like N-terminal domain	translesion synthesis	Biological process	-
CDC7	8317	cell division cycle 7	phagocytosis	Biological process	-
BZW1	9689	basic leucine zipper and W2 domains 1	membrane	Cellular component	19946888
FGD4	121512	FYVE, RhoGEF and PH domain containing 4	regulation of small GTPase mediated signal transduction	Biological process	-
RRM2	6241	ribonucleotide reductase M2	mitotic cell cycle	Biological process	-
ADRA2A	150	adrenoceptor alpha 2A	fear response	Biological process	-
ATP6V1C1	528	ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1	cytoplasmic vesicle	Cellular component	-
CD81	975	CD81 molecule	integral component of plasma membrane	Cellular component	14676841
GJA1	2697	gap junction protein, alpha 1, 43kDa	positive regulation of striated muscle tissue development	Biological process	-
SPAG16	79582	sperm associated antigen 16	spermatogenesis	Biological process	-
MBTPS2	51360	membrane-bound transcription factor peptidase, site 2	cytoplasm	Cellular component	19361614
KDM5C	8242	lysine (K)-specific demethylase 5C	rhythmic process	Biological process	-
BTN2A2	10385	butyrophilin, subfamily 2, member A2	negative regulation of cytokine secretion	Biological process	-
KIT	3815	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	Kit signaling pathway	Biological process	17662946
COL1A2	1278	collagen, type I, alpha 2	identical protein binding	Molecular function	17211858
TMPRSS11D	9407	transmembrane protease, serine 11D	serine-type endopeptidase activity	Molecular function	-
NCAPD2	9918	non-SMC condensin I complex, subunit D2	histone binding	Molecular function	10958694
TAOK1	57551	TAO kinase 1	regulation of cytoskeleton organization	Biological process	-
DRD2	1813	dopamine receptor D2	positive regulation of G-protein coupled receptor protein signaling pathway	Biological process	-
AKAP10	11216	A kinase (PRKA) anchor protein 10	signal transduction	Biological process	9326583
PRAMEF4	400735	PRAME family member 4	positive regulation of cell proliferation	Biological process	-
TNFSF13	8741	tumor necrosis factor (ligand) superfamily, member 13	cytokine activity	Molecular function	-
TUBB	203068	tubulin, beta class I	microtubule-based process	Biological process	12090300
IFT88	8100	intraflagellar transport 88	regulation of smoothened signaling pathway	Biological process	-
IGKC	3514	immunoglobulin kappa constant	immune response	Biological process	6779204
PPP1R15A	23645	protein phosphatase 1, regulatory subunit 15A	regulation of translational initiation by eIF2 alpha dephosphorylation	Biological process	12556489
PDSS1	23590	prenyl (decaprenyl) diphosphate synthase, subunit 1	transferase complex	Cellular component	16262699
MUTYH	4595	mutY homolog	base-excision repair	Biological process	-
BCL6	604	B-cell CLL/lymphoma 6	negative regulation of transcription, DNA-templated	Biological process	9135990
CHD3	1107	chromodomain helicase DNA binding protein 3	nucleus	Cellular component	9688266
ZNF830	91603	zinc finger protein 830	nuclear speck	Cellular component	-
DAB2	1601	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Biological process	12805222
MED1	5469	mediator complex subunit 1	peroxisome proliferator activated receptor signaling pathway	Biological process	-
GTF2H2	2966	general transcription factor IIH, polypeptide 2, 44kDa	protein N-terminus binding	Molecular function	8652557
MYO10	4651	myosin X	actin-dependent ATPase activity	Molecular function	-
NR4A2	4929	nuclear receptor subfamily 4, group A, member 2	regulation of dopamine metabolic process	Biological process	-
YTHDC1	91746	YTH domain containing 1	mRNA splice site selection	Biological process	20167602
PLSCR1	5359	phospholipid scramblase 1	enzyme binding	Molecular function	12586838
SEC14L1	6397	SEC14-like 1 (S. cerevisiae)	transport	Biological process	-
PLA2G1B	5319	phospholipase A2, group IB (pancreas)	extracellular space	Cellular component	12860195
CASP6	839	caspase 6, apoptosis-related cysteine peptidase	cysteine-type endopeptidase activity	Molecular function	-
RASAL1	8437	RAS protein activator like 1 (GAP1 like)	plasma membrane	Cellular component	16009725
TICAM2	353376	toll-like receptor adaptor molecule 2	inflammatory response	Biological process	-
CHPT1	56994	choline phosphotransferase 1	phosphatidylcholine biosynthetic process	Biological process	-
ZNF639	51193	zinc finger protein 639	protein self-association	Molecular function	20484494
ATP6V0A4	50617	ATPase, H+ transporting, lysosomal V0 subunit a4	transmembrane transport	Biological process	-
TYR	7299	tyrosinase	melanosome	Cellular component	-
ARL8A	127829	ADP-ribosylation factor-like 8A	chromosome segregation	Biological process	14871887
AP2B1	163	adaptor-related protein complex 2, beta 1 subunit	endocytic vesicle membrane	Cellular component	-
PCID2	55795	PCI domain containing 2	spleen development	Biological process	-
NPR3	4883	natriuretic peptide receptor 3	negative regulation of adenylate cyclase activity	Biological process	-
RAMP2	10266	receptor (G protein-coupled) activity modifying protein 2	vascular smooth muscle cell development	Biological process	-
HMGA2	8091	high mobility group AT-hook 2	protein binding	Molecular function	16293633
TUBB3	10381	tubulin, beta 3 class III	microtubule-based process	Biological process	-
CCR7	1236	chemokine (C-C motif) receptor 7	plasma membrane	Cellular component	-
ACSS3	79611	acyl-CoA synthetase short-chain family member 3	mitochondrion	Cellular component	-
C1QB	713	complement component 1, q subcomponent, B chain	protein binding	Molecular function	12960167
TMEM192	201931	transmembrane protein 192	plasma membrane	Cellular component	22736246
PSMA3	5684	proteasome (prosome, macropain) subunit, alpha type, 3	negative regulation of canonical Wnt signaling pathway	Biological process	-
TARS2	80222	threonyl-tRNA synthetase 2, mitochondrial (putative)	mitochondrial threonyl-tRNA aminoacylation	Biological process	15779907
JAM3	83700	junctional adhesion molecule 3	protein heterodimerization activity	Molecular function	-
LAMB1	3912	laminin, beta 1	negative regulation of cell adhesion	Biological process	-
CYP11A1	1583	cytochrome P450, family 11, subfamily A, polypeptide 1	heme binding	Molecular function	21636783
CLDN11	5010	claudin 11	identical protein binding	Molecular function	-
AKT1	207	v-akt murine thymoma viral oncogene homolog 1	cellular response to organic cyclic compound	Biological process	-
TNRC6C	57690	trinucleotide repeat containing 6C	nucleotide binding	Molecular function	-
MAPK15	225689	mitogen-activated protein kinase 15	positive regulation of protein phosphorylation	Biological process	-
CLCA2	9635	chloride channel accessory 2	intracellular calcium activated chloride channel activity	Molecular function	-
IMPG2	50939	interphotoreceptor matrix proteoglycan 2	extracellular matrix structural constituent	Molecular function	10702256
CSGALNACT2	55454	chondroitin sulfate N-acetylgalactosaminyltransferase 2	carbohydrate metabolic process	Biological process	-
USP14	9097	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)	cytoplasm	Cellular component	-
ZFPM1	161882	zinc finger protein, FOG family member 1	RNA polymerase II activating transcription factor binding	Molecular function	-
ERGIC3	51614	ERGIC and golgi 3	integral component of membrane	Cellular component	-
DRD2	1813	dopamine receptor D2	regulation of potassium ion transport	Biological process	-
ALK	238	anaplastic lymphoma receptor tyrosine kinase	transmembrane receptor protein tyrosine kinase activity	Molecular function	19459784
POLR1C	9533	polymerase (RNA) I polypeptide C, 30kDa	RNA polymerase III activity	Molecular function	-
TGFB2	7042	transforming growth factor, beta 2	type III transforming growth factor beta receptor binding	Molecular function	11157754
JAM3	83700	junctional adhesion molecule 3	Golgi apparatus	Cellular component	-
KCNK16	83795	potassium channel, two pore domain subfamily K, member 16	potassium ion leak channel activity	Molecular function	-
NUTF2	10204	nuclear transport factor 2	protein export from nucleus	Biological process	16449645
PLVAP	83483	plasmalemma vesicle associated protein	extracellular exosome	Cellular component	18570454
CHIC1	53344	cysteine-rich hydrophobic domain 1	transport	Biological process	-
ARPP19	10776	cAMP-regulated phosphoprotein, 19kDa	dopamine receptor signaling pathway	Biological process	-
NXF5	55998	nuclear RNA export factor 5	mRNA export from nucleus	Biological process	11566096
SOX4	6659	SRY (sex determining region Y)-box 4	sequence-specific DNA binding transcription factor activity	Molecular function	16631117
RUVBL2	10856	RuvB-like AAA ATPase 2	unfolded protein binding	Molecular function	10524211
TP53	7157	tumor protein p53	enzyme binding	Molecular function	10666337
SRF	6722	serum response factor (c-fos serum response element-binding transcription factor)	cellular senescence	Biological process	15282327
MSN	4478	moesin	leukocyte cell-cell adhesion	Biological process	12082081
SYT1	6857	synaptotagmin I	identical protein binding	Molecular function	-
POLR2E	5434	polymerase (RNA) II (DNA directed) polypeptide E, 25kDa	gene expression	Biological process	-
USP44	84101	ubiquitin specific peptidase 44	nucleolus	Cellular component	-
ABL1	25	ABL proto-oncogene 1, non-receptor tyrosine kinase	positive regulation of mitotic cell cycle	Biological process	-
NDUFAF3	25915	NADH dehydrogenase (ubiquinone) complex I, assembly factor 3	protein binding	Molecular function	19463981
GRIP1	23426	glutamate receptor interacting protein 1	androgen receptor binding	Molecular function	15572661
TMEM47	83604	transmembrane protein 47	integral component of membrane	Cellular component	-
KDM6A	7403	lysine (K)-specific demethylase 6A	notochord morphogenesis	Biological process	-
RBX1	9978	ring-box 1, E3 ubiquitin protein ligase	ubiquitin-ubiquitin ligase activity	Molecular function	10230407
PSMC5	5705	proteasome (prosome, macropain) 26S subunit, ATPase, 5	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	Biological process	-
FRAT2	23401	frequently rearranged in advanced T-cell lymphomas 2	cell proliferation	Biological process	9635432
LDLRAD1	388633	low density lipoprotein receptor class A domain containing 1	integral component of membrane	Cellular component	-
AGO2	27161	argonaute RISC catalytic component 2	siRNA binding	Molecular function	15973356
CHMP6	79643	charged multivesicular body protein 6	endosomal transport	Biological process	-
OFD1	8481	oral-facial-digital syndrome 1	G2/M transition of mitotic cell cycle	Biological process	-
UIMC1	51720	ubiquitin interaction motif containing 1	negative regulation of transcription, DNA-templated	Biological process	12080054
MARVELD2	153562	MARVEL domain containing 2	apical plasma membrane	Cellular component	23073616
RHOB	388	ras homolog family member B	late endosome membrane	Cellular component	-
SYNE2	23224	spectrin repeat containing, nuclear envelope 2	actin filament binding	Molecular function	-
LAP3	51056	leucine aminopeptidase 3	nucleoplasm	Cellular component	-
PSCA	8000	prostate stem cell antigen	plasma membrane	Cellular component	-
MCM2	4171	minichromosome maintenance complex component 2	ATP binding	Molecular function	-
APIP	51074	APAF1 interacting protein	L-methionine biosynthetic process from S-adenosylmethionine	Biological process	-
AGBL4	84871	ATP/GTP binding protein-like 4	ciliary basal body	Cellular component	23085998
ABCB6	10058	ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)	transmembrane transport	Biological process	-
CASP1	834	caspase 1, apoptosis-related cysteine peptidase	cellular response to mechanical stimulus	Biological process	19593445
MAPK3	5595	mitogen-activated protein kinase 3	toll-like receptor 3 signaling pathway	Biological process	-
THEM4	117145	thioesterase superfamily member 4	fibroblast growth factor receptor signaling pathway	Biological process	-
CCZ1	51622	CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)	lysosomal membrane	Cellular component	-
MAPK14	1432	mitogen-activated protein kinase 14	ATP binding	Molecular function	-
PSME2	5721	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)	membrane	Cellular component	19946888
UBE2L6	9246	ubiquitin-conjugating enzyme E2L 6	ligase activity	Molecular function	-
GSK3B	2932	glycogen synthase kinase 3 beta	positive regulation of peptidyl-serine phosphorylation	Biological process	-
SPAST	6683	spastin	microtubule	Cellular component	-
ZNF644	84146	zinc finger protein 644	transcription, DNA-templated	Biological process	-
SEC24D	9871	SEC24 family member D	cellular protein metabolic process	Biological process	-
SLC38A1	81539	solute carrier family 38, member 1	transmembrane transport	Biological process	-
DNAAF2	55172	dynein, axonemal, assembly factor 2	bacterial-type flagellum-dependent cell motility	Biological process	19052621
HIVEP2	3097	human immunodeficiency virus type I enhancer binding protein 2	transcription, DNA-templated	Biological process	-
PINK1	65018	PTEN induced putative kinase 1	positive regulation of sequence-specific DNA binding transcription factor activity	Biological process	-
FANCG	2189	Fanconi anemia, complementation group G	protein binding	Molecular function	10627486
STRA13	201254	stimulated by retinoic acid 13	resolution of meiotic recombination intermediates	Biological process	20347428
TRPM4	54795	transient receptor potential cation channel, subfamily M, member 4	regulation of membrane potential	Biological process	-
PIK3R1	5295	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	Fc-gamma receptor signaling pathway involved in phagocytosis	Biological process	-
ZBTB16	7704	zinc finger and BTB domain containing 16	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	12802276
TM7SF3	51768	transmembrane 7 superfamily member 3	plasma membrane	Cellular component	-
OXCT1	5019	3-oxoacid CoA transferase 1	cellular lipid metabolic process	Biological process	-
NRXN2	9379	neurexin 2	cell	Cellular component	-
BMP7	655	bone morphogenetic protein 7	negative regulation of striated muscle cell apoptotic process	Biological process	-
PTK7	5754	protein tyrosine kinase 7 (inactive)	positive regulation of neuron projection development	Biological process	17910947
BMP10	27302	bone morphogenetic protein 10	ventricular cardiac muscle tissue morphogenesis	Biological process	10072785
APC	324	adenomatous polyposis coli	protein complex assembly	Biological process	16188939
ACSL4	2182	acyl-CoA synthetase long-chain family member 4	neuronal cell body	Cellular component	-
PTEN	5728	phosphatase and tensin homolog	negative regulation of focal adhesion assembly	Biological process	9616126
CTAGE4	100128553	CTAGE family, member 4	biological_process	Biological process	-
KLHL22	84861	kelch-like family member 22	mitotic spindle	Cellular component	23455478
S100A13	6284	S100 calcium binding protein A13	zinc ion binding	Molecular function	12118070
KIF13B	23303	kinesin family member 13B	microtubule	Cellular component	-
TNKS2	80351	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2	enzyme binding	Molecular function	21251231
ABL1	25	ABL proto-oncogene 1, non-receptor tyrosine kinase	B cell proliferation involved in immune response	Biological process	-
E2F7	144455	E2F transcription factor 7	sequence-specific DNA binding transcription factor activity	Molecular function	22903062
FMOD	2331	fibromodulin	keratan sulfate biosynthetic process	Biological process	-
CD99	4267	CD99 molecule	integral component of plasma membrane	Cellular component	2465491
GHRHR	2692	growth hormone releasing hormone receptor	plasma membrane	Cellular component	-
FOXP3	50943	forkhead box P3	cytoplasm	Cellular component	16903909
CHAF1A	10036	chromatin assembly factor 1, subunit A (p150)	unfolded protein binding	Molecular function	7600578
SLC34A2	10568	solute carrier family 34 (type II sodium/phosphate cotransporter), member 2	ion transport	Biological process	-
ACAD11	84129	acyl-CoA dehydrogenase family, member 11	peroxisome	Cellular component	-
TRIM74	378108	tripartite motif containing 74	protein binding	Molecular function	25416956
SMR3B	10879	submaxillary gland androgen regulated protein 3B	protein binding	Molecular function	25416956
APH1A	51107	APH1A gamma secretase subunit	axon guidance	Biological process	-
DRAXIN	374946	dorsal inhibitory axon guidance protein	negative regulation of neuron apoptotic process	Biological process	-
MYCN	4613	v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
TBX3	6926	T-box 3	negative regulation of transcription from RNA polymerase II promoter	Biological process	11689487
HPS6	79803	Hermansky-Pudlak syndrome 6	protein localization to membrane	Biological process	22511774
FABP6	2172	fatty acid binding protein 6, ileal	lipid binding	Molecular function	-
SLC9A8	23315	solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8	hydrogen ion transmembrane transport	Biological process	-
CCR4	1233	chemokine (C-C motif) receptor 4	cytosol	Cellular component	7642634
PPP1R1B	84152	protein phosphatase 1, regulatory (inhibitor) subunit 1B	regulation of catalytic activity	Biological process	-
TCF3	6929	transcription factor 3	nucleus	Cellular component	2493990
IDE	3416	insulin-degrading enzyme	mitochondrion	Cellular component	15285718
BRCA1	672	breast cancer 1, early onset	negative regulation of fatty acid biosynthetic process	Biological process	16326698
ACTL7A	10881	actin-like 7A	nucleus	Cellular component	21630459
PAX6	5080	paired box 6	insulin metabolic process	Biological process	-
TERT	7015	telomerase reverse transcriptase	negative regulation of gene expression	Biological process	11927518
SATB2	23314	SATB homeobox 2	protein binding	Molecular function	20829881
SLC25A40	55972	solute carrier family 25, member 40	integral component of membrane	Cellular component	-
CATSPER2	117155	cation channel, sperm associated 2	multicellular organism reproduction	Biological process	-
THBS1	7057	thrombospondin 1	phosphatidylserine binding	Molecular function	18940719
TXNIP	10628	thioredoxin interacting protein	cytosol	Cellular component	-
EDF1	8721	endothelial differentiation-related factor 1	nucleolus	Cellular component	-
PYCRL	65263	pyrroline-5-carboxylate reductase-like	protein binding	Molecular function	25416956
TNFRSF8	943	tumor necrosis factor receptor superfamily, member 8	transmembrane signaling receptor activity	Molecular function	-
ACTN1	87	actinin, alpha 1	calcium ion binding	Molecular function	-
AMBP	259	alpha-1-microglobulin/bikunin precursor	female pregnancy	Biological process	10097787
EXOC1	55763	exocyst complex component 1	plasma membrane	Cellular component	-
CD302	9936	CD302 molecule	phagocytosis	Biological process	17947679
HLA-G	3135	major histocompatibility complex, class I, G	early endosome membrane	Cellular component	-
FGF10	2255	fibroblast growth factor 10	embryonic digestive tract morphogenesis	Biological process	-
VAMP1	6843	vesicle-associated membrane protein 1 (synaptobrevin 1)	cell surface	Cellular component	-
SOX15	6665	SRY (sex determining region Y)-box 15	positive regulation of G0 to G1 transition	Biological process	17363903
TLR4	7099	toll-like receptor 4	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
RAD1	5810	RAD1 checkpoint DNA exonuclease	nucleoplasm	Cellular component	-
TRIM24	8805	tripartite motif containing 24	methylated histone binding	Molecular function	21164480
PLA2G4B	100137049	phospholipase A2, group IVB (cytosolic)	extracellular region	Cellular component	10085124
SATB2	23314	SATB homeobox 2	cytoplasm	Cellular component	-
FGD3	89846	FYVE, RhoGEF and PH domain containing 3	ruffle	Cellular component	-
SNRPE	6635	small nuclear ribonucleoprotein polypeptide E	SMN-Sm protein complex	Cellular component	18984161
SLC16A14	151473	solute carrier family 16, member 14	plasma membrane	Cellular component	-
RBSN	64145	rabenosyn, RAB effector	endocytosis	Biological process	-
BAIAP2L1	55971	BAI1-associated protein 2-like 1	actin crosslink formation	Biological process	-
CA3	761	carbonic anhydrase III	small molecule metabolic process	Biological process	-
RBP2	5948	retinol binding protein 2, cellular	retinal binding	Molecular function	-
GFI1B	8328	growth factor independent 1B transcription repressor	cell proliferation	Biological process	9566867
CAMK2B	816	calcium/calmodulin-dependent protein kinase II beta	inhibitory G-protein coupled receptor phosphorylation	Biological process	-
FOXI3	344167	forkhead box I3	transcription, DNA-templated	Biological process	-
MTOR	2475	mechanistic target of rapamycin (serine/threonine kinase)	protein serine/threonine kinase activity	Molecular function	-
PTX3	5806	pentraxin 3, long	negative regulation of exo-alpha-sialidase activity	Biological process	23544079
PDLIM1	9124	PDZ and LIM domain 1	focal adhesion	Cellular component	21423176
IKBKB	3551	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	scaffold protein binding	Molecular function	23776175
CEP170B	283638	centrosomal protein 170B	microtubule	Cellular component	-
HLF	3131	hepatic leukemia factor	sequence-specific DNA binding transcription factor activity	Molecular function	-
SLC22A1	6580	solute carrier family 22 (organic cation transporter), member 1	ammonium transmembrane transport	Biological process	-
F2RL1	2150	coagulation factor II (thrombin) receptor-like 1	positive regulation of chemotaxis	Biological process	-
RTN4IP1	84816	reticulon 4 interacting protein 1	oxidation-reduction process	Biological process	-
CCNE2	9134	cyclin E2	protein binding	Molecular function	15232106
CTDSP1	58190	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1	negative regulation of neuron differentiation	Biological process	-
HAL	3034	histidine ammonia-lyase	cytosol	Cellular component	-
H2AFY	9555	H2A histone family, member Y	nucleosomal DNA binding	Molecular function	-
SERPINA3	12	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3	protein binding	Molecular function	12709365
SUCNR1	56670	succinate receptor 1	integral component of membrane	Cellular component	-
TAAR6	319100	trace amine associated receptor 6	sensory perception of chemical stimulus	Biological process	-
ZNRF3	84133	zinc and ring finger 3	ubiquitin-protein transferase activity	Molecular function	22575959
CDK5	1020	cyclin-dependent kinase 5	neuron differentiation	Biological process	21473899
TSPY4	728395	testis specific protein, Y-linked 4	cell differentiation	Biological process	-
PSMB8	5696	proteasome (prosome, macropain) subunit, beta type, 8	regulation of apoptotic process	Biological process	-
FABP6	2172	fatty acid binding protein 6, ileal	transporter activity	Molecular function	-
RPS27A	6233	ribosomal protein S27a	apoptotic process	Biological process	-
DDX11	1663	DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11	helicase activity	Molecular function	18499658
PPP2CA	5515	protein phosphatase 2, catalytic subunit, alpha isozyme	regulation of growth	Biological process	11360189
SMARCAD1	56916	SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1	protein homooligomerization	Biological process	11031099
C10orf2	56652	chromosome 10 open reading frame 2	mitochondrial nucleoid	Cellular component	18063578
DEFB108B	245911	defensin, beta 108B	innate immune response	Biological process	-
DDX5	1655	DEAD (Asp-Glu-Ala-Asp) box helicase 5	circadian rhythm	Biological process	-
NRXN1	9378	neurexin 1	adult behavior	Biological process	17034946
GMEB2	26205	glucocorticoid modulatory element binding protein 2	metal ion binding	Molecular function	-
SIAH1	6477	siah E3 ubiquitin protein ligase 1	positive regulation of apoptotic process	Biological process	21185211
GPC5	2262	glypican 5	integral component of plasma membrane	Cellular component	7657705
RAET1E	135250	retinoic acid early transcript 1E	T cell mediated cytotoxicity	Biological process	-
FDXR	2232	ferredoxin reductase	steroid metabolic process	Biological process	-
PNLIPRP2	5408	pancreatic lipase-related protein 2	extracellular space	Cellular component	18702514
CMKLR1	1240	chemerin chemokine-like receptor 1	positive regulation of fat cell differentiation	Biological process	-
PIK3R1	5295	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	plasma membrane	Cellular component	-
HIST3H3	8290	histone cluster 3, H3	nucleosome assembly	Biological process	20498094
CCS	9973	copper chaperone for superoxide dismutase	zinc ion binding	Molecular function	-
RPL22	6146	ribosomal protein L22	translational elongation	Biological process	-
TFAP2B	7021	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	positive regulation of cell proliferation	Biological process	17525748
USF1	7391	upstream transcription factor 1	sequence-specific DNA binding	Molecular function	2249772
CYP4B1	1580	cytochrome P450, family 4, subfamily B, polypeptide 1	small molecule metabolic process	Biological process	-
CLK3	1198	CDC-like kinase 3	intermediate filament cytoskeleton	Cellular component	-
RAB38	23682	RAB38, member RAS oncogene family	AP-3 adaptor complex binding	Molecular function	22511774
SKOR2	652991	SKI family transcriptional corepressor 2	cytoplasm	Cellular component	16200078
MRPL42	28977	mitochondrial ribosomal protein L42	mitochondrial translational termination	Biological process	-
ENPP1	5167	ectonucleotide pyrophosphatase/phosphodiesterase 1	zinc ion binding	Molecular function	-
STX4	6810	syntaxin 4	dendritic spine	Cellular component	20434989
ARHGAP10	79658	Rho GTPase activating protein 10	positive regulation of GTPase activity	Biological process	-
ALAS1	211	5'-aminolevulinate synthase 1	mitochondrial matrix	Cellular component	-
GCGR	2642	glucagon receptor	cellular response to glucagon stimulus	Biological process	-
ZKSCAN3	80317	zinc finger with KRAB and SCAN domains 3	cytoplasm	Cellular component	23434374
PRKAA1	5562	protein kinase, AMP-activated, alpha 1 catalytic subunit	response to hypoxia	Biological process	8557660
CARTPT	9607	CART prepropeptide	negative regulation of glucagon secretion	Biological process	-
TENM4	26011	teneurin transmembrane protein 4	positive regulation of gastrulation	Biological process	-
UNC13B	10497	unc-13 homolog B (C. elegans)	cytoplasm	Cellular component	10233166
IHH	3549	indian hedgehog	extracellular space	Cellular component	-
CHRNA4	1137	cholinergic receptor, nicotinic, alpha 4 (neuronal)	regulation of inhibitory postsynaptic membrane potential	Biological process	-
ZAN	7455	zonadhesin (gene/pseudogene)	integral component of membrane	Cellular component	-
OSTC	58505	oligosaccharyltransferase complex subunit (non-catalytic)	protein binding	Molecular function	25416956
UBC	7316	ubiquitin C	G2/M transition of mitotic cell cycle	Biological process	-
PLXNA2	5362	plexin A2	regulation of cell migration	Biological process	-
CEP164	22897	centrosomal protein 164kDa	protein binding	Molecular function	22863007
DDX3X	1654	DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked	CTPase activity	Molecular function	10074132
SPACA3	124912	sperm acrosome associated 3	extracellular region	Cellular component	16150577
IGHMBP2	3508	immunoglobulin mu binding protein 2	DNA replication	Biological process	8493094
GATA4	2626	GATA binding protein 4	RNA polymerase II transcription factor complex	Cellular component	9312027
ABCB9	23457	ATP-binding cassette, sub-family B (MDR/TAP), member 9	integral component of endoplasmic reticulum membrane	Cellular component	11011155
POTEF	728378	POTE ankyrin domain family, member F	retina homeostasis	Biological process	23580065
PLA2G4E	123745	phospholipase A2, group IVE	phosphatidylinositol acyl-chain remodeling	Biological process	-
SIX2	10736	SIX homeobox 2	anatomical structure morphogenesis	Biological process	10773454
DYX1C1	161582	dyslexia susceptibility 1 candidate 1	outer dynein arm assembly	Biological process	23872636
WNT5B	81029	wingless-type MMTV integration site family, member 5B	proteinaceous extracellular matrix	Cellular component	-
SCPEP1	59342	serine carboxypeptidase 1	serine-type carboxypeptidase activity	Molecular function	-
TH	7054	tyrosine hydroxylase	phytoalexin metabolic process	Biological process	-
PIGQ	9091	phosphatidylinositol glycan anchor biosynthesis, class Q	integral component of membrane	Cellular component	-
RBBP4	5928	retinoblastoma binding protein 4	chromatin organization	Biological process	-
PSMB7	5695	proteasome (prosome, macropain) subunit, beta type, 7	regulation of apoptotic process	Biological process	-
PTPMT1	114971	protein tyrosine phosphatase, mitochondrial 1	inositol phosphate dephosphorylation	Biological process	-
TICAM2	353376	toll-like receptor adaptor molecule 2	innate immune response	Biological process	-
ATP6V0E2	155066	ATPase, H+ transporting V0 subunit e2	transferrin transport	Biological process	-
MAP1LC3A	84557	microtubule-associated protein 1 light chain 3 alpha	autophagosome	Cellular component	12740394
CDC20	991	cell division cycle 20	cell cycle	Biological process	9682218
ACTC1	70	actin, alpha, cardiac muscle 1	muscle filament sliding	Biological process	-
ACD	65057	adrenocortical dysplasia homolog (mouse)	nucleoplasm	Cellular component	-
FIGNL1	63979	fidgetin-like 1	extracellular exosome	Cellular component	19056867
PPP2R2A	5520	protein phosphatase 2, regulatory subunit B, alpha	gene expression	Biological process	-
OR3A2	4995	olfactory receptor, family 3, subfamily A, member 2	olfactory receptor activity	Molecular function	-
E4F1	1877	E4F transcription factor 1	metal ion binding	Molecular function	-
CCND3	896	cyclin D3	signal transduction	Biological process	-
SPTLC1	10558	serine palmitoyltransferase, long chain base subunit 1	pyridoxal phosphate binding	Molecular function	-
CAPZA1	829	capping protein (actin filament) muscle Z-line, alpha 1	barbed-end actin filament capping	Biological process	-
ADGRE5	976	adhesion G protein-coupled receptor E5	protein binding	Molecular function	9064337
CFC1	55997	cripto, FRL-1, cryptic family 1	anchored component of membrane	Cellular component	-
ARID1A	8289	AT rich interactive domain 1A (SWI-like)	SWI/SNF complex	Cellular component	11078522
XYLT1	64131	xylosyltransferase I	glycosaminoglycan biosynthetic process	Biological process	11099377
CTTN	2017	cortactin	actin cytoskeleton reorganization	Biological process	-
UGT1A8	54576	UDP glucuronosyltransferase 1 family, polypeptide A8	fatty acid metabolic process	Biological process	20610558
FXR1	8087	fragile X mental retardation, autosomal homolog 1	membrane	Cellular component	19946888
PPFIBP1	8496	PTPRF interacting protein, binding protein 1 (liprin beta 1)	focal adhesion	Cellular component	21423176
OGDH	4967	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)	chaperone binding	Molecular function	-
CBS	875	cystathionine-beta-synthase	nucleolus	Cellular component	-
ABHD12	26090	abhydrolase domain containing 12	integral component of membrane	Cellular component	-
BIRC2	329	baculoviral IAP repeat containing 2	regulation of nucleotide-binding oligomerization domain containing signaling pathway	Biological process	20888210
STX3	6809	syntaxin 3	endomembrane system	Cellular component	-
TCP1	6950	t-complex 1	'de novo' posttranslational protein folding	Biological process	-
PLAG1	5324	pleiomorphic adenoma gene 1	negative regulation of gene expression	Biological process	-
OBSCN	84033	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	M band	Cellular component	11717165
PROX1	5629	prospero homeobox 1	kidney development	Biological process	8812486
ABCC10	89845	ATP-binding cassette, sub-family C (CFTR/MRP), member 10	lysosomal membrane	Cellular component	17897319
SLC25A41	284427	solute carrier family 25, member 41	mitochondrial inner membrane	Cellular component	-
ARHGDIB	397	Rho GDP dissociation inhibitor (GDI) beta	Rho protein signal transduction	Biological process	8356058
TSPAN33	340348	tetraspanin 33	integral component of membrane	Cellular component	-
KCTD10	83892	potassium channel tetramerization domain containing 10	ubiquitin-protein transferase activity	Molecular function	-
RXFP3	51289	relaxin/insulin-like family peptide receptor 3	plasma membrane	Cellular component	-
CCNK	8812	cyclin K	cyclin-dependent protein serine/threonine kinase activity	Molecular function	9632813
NR1D1	9572	nuclear receptor subfamily 1, group D, member 1	dendrite	Cellular component	-
SLC22A16	85413	solute carrier family 22 (organic cation/carnitine transporter), member 16	integral component of membrane	Cellular component	12089149
SNRPD2	6633	small nuclear ribonucleoprotein D2 polypeptide 16.5kDa	spliceosomal complex assembly	Biological process	7527560
ARHGEF3	50650	Rho guanine nucleotide exchange factor (GEF) 3	neurotrophin TRK receptor signaling pathway	Biological process	-
ORMDL2	29095	ORMDL sphingolipid biosynthesis regulator 2	ceramide metabolic process	Biological process	20182505
TAF5	6877	TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa	protein binding	Molecular function	15899866
ADH5	128	alcohol dehydrogenase 5 (class III), chi polypeptide	ethanol catabolic process	Biological process	-
RAB15	376267	RAB15, member RAS oncogene family	Rab protein signal transduction	Biological process	-
S1PR1	1901	sphingosine-1-phosphate receptor 1	transmission of nerve impulse	Biological process	-
PGR	5241	progesterone receptor	regulation of epithelial cell proliferation	Biological process	-
MYH8	4626	myosin, heavy chain 8, skeletal muscle, perinatal	cytoplasm	Cellular component	21370490
ODF4	146852	outer dense fiber of sperm tails 4	multicellular organismal development	Biological process	-
UNC45A	55898	unc-45 homolog A (C. elegans)	muscle organ development	Biological process	-
KLF9	687	Kruppel-like factor 9	DNA binding	Molecular function	-
LRRC4	64101	leucine rich repeat containing 4	postsynaptic membrane	Cellular component	-
LIMK1	3984	LIM domain kinase 1	protein phosphorylation	Biological process	23633677
SLC26A6	65010	solute carrier family 26 (anion exchanger), member 6	intracellular	Cellular component	15990874
TSACC	128229	TSSK6 activating co-chaperone	protein binding	Molecular function	25416956
DMRTA2	63950	DMRT-like family A2	cerebral cortex regionalization	Biological process	-
PPP2R1A	5518	protein phosphatase 2, regulatory subunit A, alpha	extracellular exosome	Cellular component	23533145
SAMHD1	25939	SAM domain and HD domain 1	defense response to virus	Biological process	19525956
PPOX	5498	protoporphyrinogen oxidase	oxygen-dependent protoporphyrinogen oxidase activity	Molecular function	-
MADD	8567	MAP-kinase activating death domain	negative regulation of apoptotic signaling pathway	Biological process	-
PELI3	246330	pellino E3 ubiquitin protein ligase family member 3	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	Biological process	-
STARD10	10809	StAR-related lipid transfer (START) domain containing 10	bile acid secretion	Biological process	-
EEF2	1938	eukaryotic translation elongation factor 2	plasma membrane	Cellular component	-
SART1	9092	squamous cell carcinoma antigen recognized by T cells	mRNA cis splicing, via spliceosome	Biological process	-
NGFR	4804	nerve growth factor receptor	cell surface	Cellular component	-
CARNS1	57571	carnosine synthase 1	ATP binding	Molecular function	-
PAFAH1B1	5048	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	kinesin complex	Cellular component	-
PF4V1	5197	platelet factor 4 variant 1	immune response	Biological process	-
SNCA	6622	synuclein, alpha (non A4 component of amyloid precursor)	regulation of excitatory postsynaptic membrane potential	Biological process	-
TCF3	6929	transcription factor 3	regulation of transcription, DNA-templated	Biological process	2493990
CEBPB	1051	CCAAT/enhancer binding protein (C/EBP), beta	nucleoplasm	Cellular component	-
MAP3K14	9020	mitogen-activated protein kinase kinase kinase 14	regulation of mitotic cell cycle	Biological process	-
VAMP2	6844	vesicle-associated membrane protein 2 (synaptobrevin 2)	intracellular membrane-bounded organelle	Cellular component	-
RHOQ	23433	ras homolog family member Q	GTP binding	Molecular function	-
ICAM1	3383	intercellular adhesion molecule 1	extracellular exosome	Cellular component	19056867
PAK1	5058	p21 protein (Cdc42/Rac)-activated kinase 1	apoptotic process	Biological process	-
RHOA	387	ras homolog family member A	endosome	Cellular component	19887681
TNIP2	79155	TNFAIP3 interacting protein 2	cellular response to lipopolysaccharide	Biological process	-
CFAP52	146845	cilia and flagella associated protein 52	cytoplasm	Cellular component	-
GDF6	392255	growth differentiation factor 6	pathway-restricted SMAD protein phosphorylation	Biological process	16049014
NT5C	30833	5', 3'-nucleotidase, cytosolic	purine nucleotide catabolic process	Biological process	-
CIITA	4261	class II, major histocompatibility complex, transactivator	GTP binding	Molecular function	-
ZNF91	7644	zinc finger protein 91	zinc ion binding	Molecular function	8467795
IFNG	3458	interferon, gamma	positive regulation of interleukin-23 production	Biological process	20027291
EXOSC4	54512	exosome component 4	AU-rich element binding	Molecular function	16912217
SIRT2	22933	sirtuin 2	cellular response to caloric restriction	Biological process	-
C8B	732	complement component 8, beta polypeptide	immune response	Biological process	8098723
SLC38A7	55238	solute carrier family 38, member 7	L-amino acid transmembrane transporter activity	Molecular function	-
CASP1	834	caspase 1, apoptosis-related cysteine peptidase	positive regulation of interleukin-1 beta secretion	Biological process	-
RC3H1	149041	ring finger and CCCH-type domains 1	negative regulation of activated T cell proliferation	Biological process	-
TRPM4	54795	transient receptor potential cation channel, subfamily M, member 4	cardiac conduction	Biological process	-
ATP6V1C1	528	ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1	lysosomal membrane	Cellular component	17897319
USF1	7391	upstream transcription factor 1	response to UV	Biological process	-
OR56A1	120796	olfactory receptor, family 56, subfamily A, member 1	adenylate cyclase-activating adrenergic receptor signaling pathway	Biological process	-
CHST2	9435	carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2	multicellular organismal development	Biological process	9722682
GSK3B	2932	glycogen synthase kinase 3 beta	negative regulation of glycogen (starch) synthase activity	Biological process	19366350
PSMC5	5705	proteasome (prosome, macropain) 26S subunit, ATPase, 5	proteasome complex	Cellular component	17323924
CLCF1	23529	cardiotrophin-like cytokine factor 1	B cell differentiation	Biological process	-
NFKB2	4791	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	positive regulation of transcription from RNA polymerase II promoter	Biological process	12835724
S1PR2	9294	sphingosine-1-phosphate receptor 2	integral component of membrane	Cellular component	-
EPB41L3	23136	erythrocyte membrane protein band 4.1-like 3	paranode region of axon	Cellular component	-
E4F1	1877	E4F transcription factor 1	cAMP response element binding	Molecular function	14645522
INPP1	3628	inositol polyphosphate-1-phosphatase	small molecule metabolic process	Biological process	-
HIST1H3B	8358	histone cluster 1, H3b	DNA replication-dependent nucleosome assembly	Biological process	14718166
COMMD7	149951	COMM domain containing 7	cytoplasmic membrane-bounded vesicle	Cellular component	-
IGKV4-1	28908	immunoglobulin kappa variable 4-1	innate immune response	Biological process	-
CERS1	10715	ceramide synthase 1	intracellular membrane-bounded organelle	Cellular component	-
PFKM	5213	phosphofructokinase, muscle	6-phosphofructokinase complex	Cellular component	6444532
TYMS	7298	thymidylate synthetase	organ regeneration	Biological process	-
DNAH12	201625	dynein, axonemal, heavy chain 12	microtubule motor activity	Molecular function	-
WWOX	51741	WW domain containing oxidoreductase	RNA polymerase II transcription factor complex	Cellular component	19366691
ACVR2B	93	activin A receptor, type IIB	receptor complex	Cellular component	9872992
SERPINE1	5054	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	extracellular matrix organization	Biological process	-
GRIN1	2902	glutamate receptor, ionotropic, N-methyl D-aspartate 1	regulation of respiratory gaseous exchange	Biological process	-
HDAC2	3066	histone deacetylase 2	deacetylase activity	Molecular function	-
PHOSPHO2	493911	phosphatase, orphan 2	dephosphorylation	Biological process	-
ZNF669	79862	zinc finger protein 669	regulation of transcription, DNA-templated	Biological process	-
RILPL2	196383	Rab interacting lysosomal protein-like 2	cytosol	Cellular component	-
SYF2	25949	SYF2 pre-mRNA-splicing factor	poly(A) RNA binding	Molecular function	22658674
CABIN1	23523	calcineurin binding protein 1	DNA replication-independent nucleosome assembly	Biological process	14718166
CFLAR	8837	CASP8 and FADD-like apoptosis regulator	death receptor binding	Molecular function	-
VARS	7407	valyl-tRNA synthetase	valine-tRNA ligase activity	Molecular function	8428657
PENK	5179	proenkephalin	neuropeptide hormone activity	Molecular function	7057924
RAB3D	9545	RAB3D, member RAS oncogene family	synaptic vesicle	Cellular component	-
DIXDC1	85458	DIX domain containing 1	axon terminus	Cellular component	-
PROX1	5629	prospero homeobox 1	ventricular cardiac muscle tissue morphogenesis	Biological process	-
GRK5	2869	G protein-coupled receptor kinase 5	nuclear membrane	Cellular component	-
SLC11A2	4891	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2	zinc ion binding	Molecular function	-
HADHB	3032	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit	poly(A) RNA binding	Molecular function	22658674
MYCL	4610	v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog	regulation of transcription, DNA-templated	Biological process	-
ZNF703	80139	zinc finger protein 703	adherens junction assembly	Biological process	-
RBM15B	29890	RNA binding motif protein 15B	nucleoplasm	Cellular component	-
H6PD	9563	hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)	glucose-6-phosphate dehydrogenase activity	Molecular function	-
HOPX	84525	HOP homeobox	negative regulation of cell differentiation	Biological process	17576768
SRP9	6726	signal recognition particle 9kDa	translation	Biological process	-
BEGAIN	57596	brain-enriched guanylate kinase-associated	membrane	Cellular component	-
RPL14	9045	ribosomal protein L14	extracellular exosome	Cellular component	20458337
OVCH1	341350	ovochymase 1	metal ion binding	Molecular function	-
CDC42BPG	55561	CDC42 binding protein kinase gamma (DMPK-like)	cell leading edge	Cellular component	15194684
DDX1	1653	DEAD (Asp-Glu-Ala-Asp) box helicase 1	protein binding	Molecular function	11598190
NCS1	23413	neuronal calcium sensor 1	calcium ion transmembrane transport	Biological process	-
BHLHB9	80823	basic helix-loop-helix domain containing, class B, 9	negative regulation of neuron apoptotic process	Biological process	-
HRC	3270	histidine rich calcium binding protein	ATPase binding	Molecular function	17526652
FMO1	2326	flavin containing monooxygenase 1	toxin metabolic process	Biological process	15144220
BLNK	29760	B-cell linker	plasma membrane	Cellular component	-
LEFTY1	10637	left-right determination factor 1	transforming growth factor beta receptor binding	Molecular function	-
SH3GLB1	51100	SH3-domain GRB2-like endophilin B1	mitochondrial outer membrane	Cellular component	-
SLC5A7	60482	solute carrier family 5 (sodium/choline cotransporter), member 7	neurotransmitter secretion	Biological process	-
TMEM147	10430	transmembrane protein 147	integral component of membrane	Cellular component	-
APP	351	amyloid beta (A4) precursor protein	mRNA polyadenylation	Biological process	-
JUN	3725	jun proto-oncogene	membrane depolarization	Biological process	-
PPP1R2P1	100507444	protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 1	negative regulation of catalytic activity	Biological process	-
CCDC174	51244	coiled-coil domain containing 174	nucleoplasm	Cellular component	-
DBI	1622	diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)	long-chain fatty acyl-CoA binding	Molecular function	21079819
STX7	8417	syntaxin 7	vesicle docking	Biological process	-
VAT1	10493	vesicle amine transport 1	mitochondrial outer membrane	Cellular component	-
CXCL13	10563	chemokine (C-X-C motif) ligand 13	activation of GTPase activity	Biological process	-
MID2	11043	midline 2	protein homodimerization activity	Molecular function	11806752
TCTE3	6991	t-complex-associated-testis-expressed 3	transport	Biological process	-
SETDB1	9869	SET domain, bifurcated 1	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
TINAGL1	64129	tubulointerstitial nephritis antigen-like 1	scavenger receptor activity	Molecular function	-
APH1A	51107	APH1A gamma secretase subunit	protein binding	Molecular function	12297508
CST8	10047	cystatin 8 (cystatin-related epididymal specific)	cytoplasm	Cellular component	-
HNRNPM	4670	heterogeneous nuclear ribonucleoprotein M	nucleolus	Cellular component	-
SPP1	6696	secreted phosphoprotein 1	extracellular matrix disassembly	Biological process	-
PPP1R7	5510	protein phosphatase 1, regulatory subunit 7	protein binding	Molecular function	25416956
TOPBP1	11073	topoisomerase (DNA) II binding protein 1	condensed nuclear chromosome	Cellular component	-
UBR5	51366	ubiquitin protein ligase E3 component n-recognin 5	positive regulation of catenin import into nucleus	Biological process	21118991
FGF20	26281	fibroblast growth factor 20	cell-cell signaling	Biological process	10913340
GRHL2	79977	grainyhead-like 2 (Drosophila)	cell junction assembly	Biological process	25152456
MYB	4602	v-myb avian myeloblastosis viral oncogene homolog	positive regulation of transcription from RNA polymerase II promoter	Biological process	20531406
ETF1	2107	eukaryotic translation termination factor 1	translational termination	Biological process	-
ARSH	347527	arylsulfatase family, member H	endoplasmic reticulum lumen	Cellular component	-
P2RX7	5027	purinergic receptor P2X, ligand gated ion channel, 7	positive regulation of interleukin-1 beta secretion	Biological process	17036048
SEZ6L2	26470	seizure related 6 homolog (mouse)-like 2	integral component of membrane	Cellular component	-
CWC27	10283	CWC27 spliceosome-associated protein homolog (S. cerevisiae)	mRNA splicing, via spliceosome	Biological process	11991638
PIWIL2	55124	piwi-like RNA-mediated gene silencing 2	RNA 5'-end processing	Biological process	-
UNC50	25972	unc-50 homolog (C. elegans)	protein transport	Biological process	-
SCARB1	949	scavenger receptor class B, member 1	1-phosphatidylinositol binding	Molecular function	9211901
NAA16	79612	N(alpha)-acetyltransferase 16, NatA auxiliary subunit	cytoplasm	Cellular component	-
IGFBP3	3486	insulin-like growth factor binding protein 3	positive regulation of MAPK cascade	Biological process	-
PSMB11	122706	proteasome (prosome, macropain) subunit, beta type, 11	positive regulation of canonical Wnt signaling pathway	Biological process	-
SNX3	8724	sorting nexin 3	retromer complex	Cellular component	21725319
XBP1	7494	X-box binding protein 1	sequence-specific DNA binding RNA polymerase II transcription factor activity	Molecular function	-
FOXA2	3170	forkhead box A2	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	12642491
SEPP1	6414	selenoprotein P, plasma, 1	extracellular region	Cellular component	14718574
RPS6	6194	ribosomal protein S6	cell body	Cellular component	15121898
OR10Q1	219960	olfactory receptor, family 10, subfamily Q, member 1	G-protein coupled receptor activity	Molecular function	-
PCNA	5111	proliferating cell nuclear antigen	nucleoplasm	Cellular component	-
MAP3K1	4214	mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase	regulation of mitotic cell cycle	Biological process	-
COG8	84342	component of oligomeric golgi complex 8	membrane	Cellular component	19946888
RNASE4	6038	ribonuclease, RNase A family, 4	cellular response to starvation	Biological process	-
TBX19	9095	T-box 19	regulation of cell proliferation	Biological process	-
UBE2G1	7326	ubiquitin-conjugating enzyme E2G 1	protein K48-linked ubiquitination	Biological process	20061386
FOLH1B	219595	folate hydrolase 1B	metal ion binding	Molecular function	-
ABCA3	21	ATP-binding cassette, sub-family A (ABC1), member 3	transporter activity	Molecular function	9027511
ARF6	382	ADP-ribosylation factor 6	thioesterase binding	Molecular function	15509780
ACTB	60	actin, beta	kinesin binding	Molecular function	18680169
OR10C1	442194	olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)	G-protein coupled receptor signaling pathway	Biological process	-
BNC2	54796	basonuclin 2	regulation of transcription, DNA-templated	Biological process	-
ITGA5	3678	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	integrin binding	Molecular function	-
RTN1	6252	reticulon 1	endoplasmic reticulum membrane	Cellular component	17684057
MICALL1	85377	MICAL-like 1	cellular response to nerve growth factor stimulus	Biological process	-
CHD3	1107	chromodomain helicase DNA binding protein 3	cytoplasm	Cellular component	17626165
DNMT3A	1788	DNA (cytosine-5-)-methyltransferase 3 alpha	C-5 methylation of cytosine	Biological process	-
TCF4	6925	transcription factor 4	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	8978694
PRKG2	5593	protein kinase, cGMP-dependent, type II	cGMP-dependent protein kinase activity	Molecular function	-
SCAI	286205	suppressor of cancer cell invasion	integral component of membrane	Cellular component	-
SULT1B1	27284	sulfotransferase family, cytosolic, 1B, member 1	small molecule metabolic process	Biological process	-
WT1	7490	Wilms tumor 1	adrenal cortex formation	Biological process	-
NDUFAF3	25915	NADH dehydrogenase (ubiquinone) complex I, assembly factor 3	mitochondrial respiratory chain complex I assembly	Biological process	19463981
GRAMD3	65983	GRAM domain containing 3	protein binding	Molecular function	25416956
DYNLL1	8655	dynein, light chain, LC8-type 1	COP9 signalosome	Cellular component	18850735
OR5T1	390155	olfactory receptor, family 5, subfamily T, member 1	plasma membrane	Cellular component	-
GPC3	2719	glypican 3	peptidyl-dipeptidase inhibitor activity	Molecular function	17549790
CYB5A	1528	cytochrome b5 type A (microsomal)	mitochondrial outer membrane	Cellular component	-
CDKN1C	1028	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	cyclin-dependent protein serine/threonine kinase inhibitor activity	Molecular function	-
ASS1	445	argininosuccinate synthase 1	extracellular exosome	Cellular component	19056867
CHD4	1108	chromodomain helicase DNA binding protein 4	RNA polymerase II repressing transcription factor binding	Molecular function	22926524
IL17RB	55540	interleukin 17 receptor B	cytokine receptor activity	Molecular function	10815801
OR52N2	390077	olfactory receptor, family 52, subfamily N, member 2	integral component of membrane	Cellular component	-
CACNG2	10369	calcium channel, voltage-dependent, gamma subunit 2	voltage-gated calcium channel complex	Cellular component	-
ADORA1	134	adenosine A1 receptor	response to hypoxia	Biological process	-
TAF7L	54457	TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa	transcription factor TFIID complex	Cellular component	-
FFAR2	2867	free fatty acid receptor 2	lipid storage	Biological process	-
DIS3L	115752	DIS3 like exosome 3'-5' exoribonuclease	centrosome	Cellular component	-
CPSF1	29894	cleavage and polyadenylation specific factor 1, 160kDa	mRNA cleavage	Biological process	7590244
IQGAP3	128239	IQ motif containing GTPase activating protein 3	activation of MAPK activity	Biological process	-
RBM27	54439	RNA binding motif protein 27	mRNA processing	Biological process	-
KIR2DL2	3803	killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2	plasma membrane	Cellular component	-
PALM	5064	paralemmin	cytoskeleton organization	Biological process	-
BDKRB2	624	bradykinin receptor B2	smooth muscle contraction	Biological process	17077303
IL4	3565	interleukin 4	regulation of isotype switching	Biological process	11418631
UBE2B	7320	ubiquitin-conjugating enzyme E2B	maintenance of chromatin silencing	Biological process	-
VPS26B	112936	vacuolar protein sorting 26 homolog B (S. pombe)	retrograde transport, endosome to Golgi	Biological process	-
SUMO3	6612	small ubiquitin-like modifier 3	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	-
CLIP3	25999	CAP-GLY domain containing linker protein 3	membrane biogenesis	Biological process	11854307
IRS1	3667	insulin receptor substrate 1	positive regulation of cell proliferation	Biological process	17925406
SFRP2	6423	secreted frizzled-related protein 2	negative regulation of JUN kinase activity	Biological process	-
NEIL2	252969	nei endonuclease VIII-like 2 (E. coli)	nucleoplasm	Cellular component	-
OR8A1	390275	olfactory receptor, family 8, subfamily A, member 1	plasma membrane	Cellular component	-
EREG	2069	epiregulin	growth factor activity	Molecular function	-
AGK	55750	acylglycerol kinase	intracellular membrane-bounded organelle	Cellular component	-
FOXP1	27086	forkhead box P1	response to lipopolysaccharide	Biological process	18799727
EPHX2	2053	epoxide hydrolase 2, cytoplasmic	small molecule metabolic process	Biological process	-
RASD2	23551	RASD family, member 2	positive regulation of protein sumoylation	Biological process	-
BST1	683	bone marrow stromal cell antigen 1	extracellular exosome	Cellular component	23376485
OR7D2	162998	olfactory receptor, family 7, subfamily D, member 2	plasma membrane	Cellular component	-
FLT3LG	2323	fms-related tyrosine kinase 3 ligand	protein homodimerization activity	Molecular function	-
ETS1	2113	v-ets avian erythroblastosis virus E26 oncogene homolog 1	response to interleukin-1	Biological process	-
VEGFA	7422	vascular endothelial growth factor A	dopaminergic neuron differentiation	Biological process	-
NUDT5	11164	nudix (nucleoside diphosphate linked moiety X)-type motif 5	intracellular	Cellular component	10567213
PCK2	5106	phosphoenolpyruvate carboxykinase 2 (mitochondrial)	phosphoenolpyruvate carboxykinase activity	Molecular function	8645161
FGFR1	2260	fibroblast growth factor receptor 1	chordate embryonic development	Biological process	15863030
OTUD4	54726	OTU deubiquitinase 4	protein K48-linked deubiquitination	Biological process	23827681
PMEL	6490	premelanosome protein	endoplasmic reticulum membrane	Cellular component	15695812
RILP	83547	Rab interacting lysosomal protein	late endosome	Cellular component	11179213
EPRS	2058	glutamyl-prolyl-tRNA synthetase	GTPase binding	Molecular function	24337748
FOXJ1	2302	forkhead box J1	spermatogenesis	Biological process	9073514
MATK	4145	megakaryocyte-associated tyrosine kinase	protein phosphorylation	Biological process	7530249
ZDHHC22	283576	zinc finger, DHHC-type containing 22	protein palmitoylation	Biological process	-
DTNB	1838	dystrobrevin, beta	zinc ion binding	Molecular function	-
PCBD1	5092	pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha	identical protein binding	Molecular function	16189514
ACHE	43	acetylcholinesterase (Yt blood group)	muscle organ development	Biological process	11283752
DARS	1615	aspartyl-tRNA synthetase	aminoacylase activity	Molecular function	8449960
DUSP2	1844	dual specificity phosphatase 2	MAP kinase tyrosine/serine/threonine phosphatase activity	Molecular function	-
RIC8A	60626	RIC8 guanine nucleotide exchange factor A	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway	Biological process	-
ZNF763	284390	zinc finger protein 763	extracellular exosome	Cellular component	23376485
SMIM13	221710	small integral membrane protein 13	integral component of membrane	Cellular component	-
ZNF366	167465	zinc finger protein 366	estrogen receptor binding	Molecular function	17085477
FBLN5	10516	fibulin 5	extracellular matrix	Cellular component	20551380
ADAR	103	adenosine deaminase, RNA-specific	nucleolus	Cellular component	-
PTPN22	26191	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	regulation of B cell receptor signaling pathway	Biological process	19265110
STOX1	219736	storkhead box 1	regulation of transcription from RNA polymerase II promoter in response to hypoxia	Biological process	24738702
MYH14	79784	myosin, heavy chain 14, non-muscle	actin-dependent ATPase activity	Molecular function	24072716
EXOSC5	56915	exosome component 5	polyadenylation-dependent snoRNA 3'-end processing	Biological process	-
CCR7	1236	chemokine (C-C motif) receptor 7	lymphocyte migration into lymph node	Biological process	18379575
CD300LG	146894	CD300 molecule-like family member g	immunoglobulin transcytosis in epithelial cells	Biological process	-
ELK3	2004	ELK3, ETS-domain protein (SRF accessory protein 2)	signal transduction	Biological process	7958835
IFNA16	3449	interferon, alpha 16	type I interferon receptor binding	Molecular function	6548765
SI	6476	sucrase-isomaltase (alpha-glucosidase)	carbohydrate binding	Molecular function	-
PLET1	349633	placenta expressed transcript 1	cell differentiation	Biological process	-
TPO	7173	thyroid peroxidase	response to oxidative stress	Biological process	-
ZNF200	7752	zinc finger protein 200	regulation of transcription, DNA-templated	Biological process	-
DNAJC6	9829	DnaJ (Hsp40) homolog, subfamily C, member 6	regulation of clathrin-mediated endocytosis	Biological process	-
NPC2	10577	Niemann-Pick disease, type C2	glycolipid transport	Biological process	17018531
GPER1	2852	G protein-coupled estrogen receptor 1	positive regulation of cAMP biosynthetic process	Biological process	15539556
DDX41	51428	DEAD (Asp-Glu-Ala-Asp) box polypeptide 41	apoptotic process	Biological process	10607561
LATS2	26524	large tumor suppressor kinase 2	cytoplasm	Cellular component	-
SIGLEC1	6614	sialic acid binding Ig-like lectin 1, sialoadhesin	positive regulation of T cell apoptotic process	Biological process	-
NOL4L	140688	nucleolar protein 4-like	cytoplasm	Cellular component	-
ZP3	7784	zona pellucida glycoprotein 3 (sperm receptor)	acrosomal vesicle	Cellular component	-
EPS8L1	54869	EPS8-like 1	Rho guanyl-nucleotide exchange factor activity	Molecular function	14565974
SDHC	6391	succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa	small molecule metabolic process	Biological process	-
LRRK2	120892	leucine-rich repeat kinase 2	response to oxidative stress	Biological process	19692353
SSPN	8082	sarcospan	muscle contraction	Biological process	9395445
CSPG4	1464	chondroitin sulfate proteoglycan 4	protein kinase binding	Molecular function	10587647
CYB5R4	51167	cytochrome b5 reductase 4	endoplasmic reticulum	Cellular component	15131110
DYRK1A	1859	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	circadian rhythm	Biological process	-
DAD1	1603	defender against cell death 1	negative regulation of apoptotic process	Biological process	-
PRMT5	10419	protein arginine methyltransferase 5	cell proliferation	Biological process	9843966
VPS4A	27183	vacuolar protein sorting 4 homolog A (S. cerevisiae)	vesicle-mediated transport	Biological process	11563910
ERAP1	51752	endoplasmic reticulum aminopeptidase 1	angiogenesis	Biological process	15691326
TGFB1	7040	transforming growth factor, beta 1	positive regulation of smooth muscle cell differentiation	Biological process	-
TEK	7010	TEK tyrosine kinase, endothelial	positive regulation of angiogenesis	Biological process	18425120
UGT1A4	54657	UDP glucuronosyltransferase 1 family, polypeptide A4	flavonoid glucuronidation	Biological process	-
TRIM4	89122	tripartite motif containing 4	protein trimerization	Biological process	17156811
RNF20	56254	ring finger protein 20, E3 ubiquitin protein ligase	negative regulation of mRNA polyadenylation	Biological process	19575011
MS4A3	932	membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)	regulation of cell cycle	Biological process	-
SUSD6	9766	sushi domain containing 6	protein binding	Molecular function	25416956
CATSPER2	117155	cation channel, sperm associated 2	membrane depolarization during action potential	Biological process	-
BRSK2	9024	BR serine/threonine kinase 2	establishment of cell polarity	Biological process	-
OR52N4	390072	olfactory receptor, family 52, subfamily N, member 4 (gene/pseudogene)	G-protein coupled receptor activity	Molecular function	-
CAND1	55832	cullin-associated and neddylation-dissociated 1	TBP-class protein binding	Molecular function	-
PSMA8	143471	proteasome (prosome, macropain) subunit, alpha type, 8	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	Biological process	-
NFATC3	4775	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	inflammatory response	Biological process	7739550
MAPK14	1432	mitogen-activated protein kinase 14	stress-activated MAPK cascade	Biological process	-
COL28A1	340267	collagen, type XXVIII, alpha 1	extracellular region	Cellular component	-
OSBPL3	26031	oxysterol binding protein-like 3	membrane	Cellular component	19946888
SPHK1	8877	sphingosine kinase 1	cellular response to hydrogen peroxide	Biological process	-
AKR1B15	441282	aldo-keto reductase family 1, member B15	oxidation-reduction process	Biological process	-
OR5J2	282775	olfactory receptor, family 5, subfamily J, member 2	sensory perception of smell	Biological process	-
ZFYVE16	9765	zinc finger, FYVE domain containing 16	metal ion binding	Molecular function	-
RARA	5914	retinoic acid receptor, alpha	steroid hormone mediated signaling pathway	Biological process	-
EIF3E	3646	eukaryotic translation initiation factor 3, subunit E	nucleoplasm	Cellular component	17468741
CENPK	64105	centromere protein K	condensed chromosome kinetochore	Cellular component	-
KIF9	64147	kinesin family member 9	regulation of podosome assembly	Biological process	21119006
SELP	6403	selectin P (granule membrane protein 140kDa, antigen CD62)	integral component of plasma membrane	Cellular component	1701178
CDKN2AIP	55602	CDKN2A interacting protein	regulation of protein stability	Biological process	12154087
ILK	3611	integrin-linked kinase	protein complex	Cellular component	-
RSPH6A	81492	radial spoke head 6 homolog A (Chlamydomonas)	intracellular	Cellular component	-
TMPRSS2	7113	transmembrane protease, serine 2	proteolysis	Biological process	21068237
ASIC2	40	acid sensing (proton gated) ion channel 2	integral component of plasma membrane	Cellular component	-
MTFMT	123263	mitochondrial methionyl-tRNA formyltransferase	conversion of methionyl-tRNA to N-formyl-methionyl-tRNA	Biological process	-
ZFPM2	23414	zinc finger protein, FOG family member 2	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
TREM1	54210	triggering receptor expressed on myeloid cells 1	extracellular region	Cellular component	-
GRM2	2912	glutamate receptor, metabotropic 2	G-protein coupled glutamate receptor signaling pathway	Biological process	-
CSF1	1435	colony stimulating factor 1 (macrophage)	plasma membrane	Cellular component	-
VAV1	7409	vav 1 guanine nucleotide exchange factor	fibroblast growth factor receptor signaling pathway	Biological process	-
MICA	100507436	MHC class I polypeptide-related sequence A	gamma-delta T cell activation	Biological process	9497295
DPEP1	1800	dipeptidase 1 (renal)	cellular response to drug	Biological process	20435919
GDF5	8200	growth differentiation factor 5	intracellular	Cellular component	21976273
ERN1	2081	endoplasmic reticulum to nucleus signaling 1	RNA phosphodiester bond hydrolysis, endonucleolytic	Biological process	-
C9orf142	286257	chromosome 9 open reading frame 142	protein homodimerization activity	Molecular function	25574025
PSMD10	5716	proteasome (prosome, macropain) 26S subunit, non-ATPase, 10	positive regulation of protein ubiquitination	Biological process	16023600
MEOX2	4223	mesenchyme homeobox 2	multicellular organismal development	Biological process	7713505
STX16	8675	syntaxin 16	retrograde transport, endosome to Golgi	Biological process	17389686
PLGRKT	55848	plasminogen receptor, C-terminal lysine transmembrane protein	positive regulation of plasminogen activation	Biological process	-
TARDBP	23435	TAR DNA binding protein	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
SDC2	6383	syndecan 2	lysosomal lumen	Cellular component	-
CHCHD3	54927	coiled-coil-helix-coiled-coil-helix domain containing 3	protein complex scaffold	Molecular function	-
RXFP3	51289	relaxin/insulin-like family peptide receptor 3	positive regulation of cytokinesis	Biological process	22888021
CATSPER3	347732	cation channel, sperm associated 3	sperm motility	Biological process	-
PKN1	5585	protein kinase N1	nucleus	Cellular component	12514133
OXA1L	5018	oxidase (cytochrome c) assembly 1-like	mitochondrion	Cellular component	-
TPR	7175	translocated promoter region, nuclear basket protein	positive regulation of heterochromatin assembly	Biological process	20407419
RAMP3	10268	receptor (G protein-coupled) activity modifying protein 3	intracellular protein transport	Biological process	-
CCT2	10576	chaperonin containing TCP1, subunit 2 (beta)	chaperonin-containing T-complex	Cellular component	23011926
PAK1	5058	p21 protein (Cdc42/Rac)-activated kinase 1	neuromuscular junction development	Biological process	-
ALS2	57679	amyotrophic lateral sclerosis 2 (juvenile)	receptor recycling	Biological process	-
PEG3	5178	paternally expressed 3	in utero embryonic development	Biological process	-
ANAPC4	29945	anaphase promoting complex subunit 4	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition	Biological process	-
ACP5	54	acid phosphatase 5, tartrate resistant	lysosome	Cellular component	-
P2RX6	9127	purinergic receptor P2X, ligand gated ion channel, 6	purinergic nucleotide receptor activity	Molecular function	12088286
SLC7A4	6545	solute carrier family 7, member 4	antiporter activity	Molecular function	-
CCT6A	908	chaperonin containing TCP1, subunit 6A (zeta 1)	poly(A) RNA binding	Molecular function	22658674
CALM3	808	calmodulin 3 (phosphorylase kinase, delta)	negative regulation of ryanodine-sensitive calcium-release channel activity	Biological process	-
LAMP2	3920	lysosomal-associated membrane protein 2	platelet degranulation	Biological process	-
GRIA3	2892	glutamate receptor, ionotropic, AMPA 3	plasma membrane	Cellular component	-
AKAP7	9465	A kinase (PRKA) anchor protein 7	ion transport	Biological process	9545239
ZNF45	7596	zinc finger protein 45	DNA binding	Molecular function	-
ZNF227	7770	zinc finger protein 227	nucleus	Cellular component	-
CASP8	841	caspase 8, apoptosis-related cysteine peptidase	death-inducing signaling complex assembly	Biological process	-
DROSHA	29102	drosha, ribonuclease type III	miRNA metabolic process	Biological process	-
WNT8A	7478	wingless-type MMTV integration site family, member 8A	proteinaceous extracellular matrix	Cellular component	-
CTGF	1490	connective tissue growth factor	epidermis development	Biological process	10809757
IFNG	3458	interferon, gamma	interferon-gamma receptor binding	Molecular function	-
PSMB7	5695	proteasome (prosome, macropain) subunit, beta type, 7	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition	Biological process	-
FLOT1	10211	flotillin 1	positive regulation of myoblast fusion	Biological process	24046456
HMGCR	3156	3-hydroxy-3-methylglutaryl-CoA reductase	coenzyme binding	Molecular function	10698924
GLUL	2752	glutamate-ammonia ligase	response to glucose	Biological process	-
SYNCRIP	10492	synaptotagmin binding, cytoplasmic RNA interacting protein	negative regulation of translation	Biological process	15479637
MYD88	4615	myeloid differentiation primary response 88	neurotrophin TRK receptor signaling pathway	Biological process	-
PPP1CA	5499	protein phosphatase 1, catalytic subunit, alpha isozyme	nucleus	Cellular component	11739654
CCNA2	890	cyclin A2	regulation of cyclin-dependent protein serine/threonine kinase activity	Biological process	-
NTF3	4908	neurotrophin 3	growth factor activity	Molecular function	23027130
MYLPF	29895	myosin light chain, phosphorylatable, fast skeletal muscle	muscle contraction	Biological process	-
CYP11A1	1583	cytochrome P450, family 11, subfamily A, polypeptide 1	cellular response to lipopolysaccharide	Biological process	-
PTGES	9536	prostaglandin E synthase	arachidonic acid metabolic process	Biological process	-
ATP5L	10632	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)	Cellular component	-
PRKAA1	5562	protein kinase, AMP-activated, alpha 1 catalytic subunit	insulin receptor signaling pathway	Biological process	-
TM7SF2	7108	transmembrane 7 superfamily member 2	endoplasmic reticulum membrane	Cellular component	-
SUFU	51684	suppressor of fused homolog (Drosophila)	protein kinase binding	Molecular function	20643644
FGFR2	2263	fibroblast growth factor receptor 2	lung development	Biological process	-
DCLK1	9201	doublecortin-like kinase 1	neuron migration	Biological process	-
ABCC1	4363	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	arachidonic acid metabolic process	Biological process	-
TP53	7157	tumor protein p53	circadian behavior	Biological process	-
NBN	4683	nibrin	positive regulation of protein autophosphorylation	Biological process	15790808
TLL1	7092	tolloid-like 1	collagen binding	Molecular function	-
CCT6A	908	chaperonin containing TCP1, subunit 6A (zeta 1)	ATP binding	Molecular function	-
FUT2	2524	fucosyltransferase 2 (secretor status included)	galactoside 2-alpha-L-fucosyltransferase activity	Molecular function	11698403
TANK	10010	TRAF family member-associated NFKB activator	metal ion binding	Molecular function	-
APC	324	adenomatous polyposis coli	beta-catenin destruction complex	Cellular component	16188939
GK5	256356	glycerol kinase 5 (putative)	glycerol catabolic process	Biological process	-
MMP9	4318	matrix metallopeptidase 9	protein binding	Molecular function	16512877
CDC16	8881	cell division cycle 16	cell division	Biological process	-
CDK5RAP2	55755	CDK5 regulatory subunit associated protein 2	microtubule	Cellular component	19553473
PSMA4	5685	proteasome (prosome, macropain) subunit, alpha type, 4	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological process	-
TRAF3	7187	TNF receptor-associated factor 3	regulation of apoptotic process	Biological process	-
MAB21L1	4081	mab-21-like 1 (C. elegans)	camera-type eye development	Biological process	-
ZNF814	730051	zinc finger protein 814	intracellular	Cellular component	-
GRIN2A	2903	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	response to drug	Biological process	-
RPL18	6141	ribosomal protein L18	translational termination	Biological process	-
PPP2R5D	5528	protein phosphatase 2, regulatory subunit B', delta	cytosol	Cellular component	-
TGM7	116179	transglutaminase 7	protein-glutamine gamma-glutamyltransferase activity	Molecular function	-
VPS37A	137492	vacuolar protein sorting 37 homolog A (S. cerevisiae)	viral life cycle	Biological process	-
HABP2	3026	hyaluronan binding protein 2	proteolysis	Biological process	-
AURKA	6790	aurora kinase A	chromosome passenger complex	Cellular component	-
HHEX	3087	hematopoietically expressed homeobox	multicellular organism growth	Biological process	-
RAB1B	81876	RAB1B, member RAS oncogene family	pre-autophagosomal structure membrane	Cellular component	20545908
BACE1	23621	beta-site APP-cleaving enzyme 1	protein binding	Molecular function	16407538
MECOM	2122	MDS1 and EVI1 complex locus	renal system development	Biological process	-
METTL3	56339	methyltransferase like 3	mRNA destabilization	Biological process	-
ADI1	55256	acireductone dioxygenase 1	cytoplasm	Cellular component	11602742
SNX9	51429	sorting nexin 9	cytoplasmic membrane-bounded vesicle	Cellular component	15703209
MARK3	4140	MAP/microtubule affinity-regulating kinase 3	protein phosphorylation	Biological process	-
RHOA	387	ras homolog family member A	GTP binding	Molecular function	-
IDO1	3620	indoleamine 2,3-dioxygenase 1	positive regulation of type 2 immune response	Biological process	-
NRG1	3084	neuregulin 1	cytokine activity	Molecular function	10372964
SLC39A7	7922	solute carrier family 39 (zinc transporter), member 7	transmembrane transport	Biological process	-
ZMYND8	23613	zinc finger, MYND-type containing 8	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
AGBL2	79841	ATP/GTP binding protein-like 2	metallocarboxypeptidase activity	Molecular function	-
NEFH	4744	neurofilament, heavy polypeptide	protein kinase binding	Molecular function	9313898
GNPDA2	132789	glucosamine-6-phosphate deaminase 2	hydrolase activity	Molecular function	-
NINJ1	4814	ninjurin 1	positive regulation of cell-matrix adhesion	Biological process	-
ATP1A2	477	ATPase, Na+/K+ transporting, alpha 2 polypeptide	neurotransmitter uptake	Biological process	-
NME1	4830	NME/NM23 nucleoside diphosphate kinase 1	CTP biosynthetic process	Biological process	-
RIMS3	9783	regulating synaptic membrane exocytosis 3	neurotransmitter transport	Biological process	-
ACVR2A	92	activin A receptor, type IIA	signal transduction by protein phosphorylation	Biological process	-
CHD1	1105	chromodomain helicase DNA binding protein 1	nucleus	Cellular component	22046413
DNAJC19	131118	DnaJ (Hsp40) homolog, subfamily C, member 19	integral component of membrane	Cellular component	16055927
NCAPG2	54892	non-SMC condensin II complex, subunit G2	nucleoplasm	Cellular component	-
BTRC	8945	beta-transducin repeat containing E3 ubiquitin protein ligase	regulation of proteasomal protein catabolic process	Biological process	-
FLT4	2324	fms-related tyrosine kinase 4	protein phosphatase binding	Molecular function	20826270
ACBD5	91452	acyl-CoA binding domain containing 5	nucleus	Cellular component	-
POLR2G	5436	polymerase (RNA) II (DNA directed) polypeptide G	nuclear-transcribed mRNA catabolic process, exonucleolytic	Biological process	-
DOC2B	8447	double C2-like domains, beta	positive regulation of vesicle fusion	Biological process	-
KL	9365	klotho	extracellular space	Cellular component	11792841
AGPAT3	56894	1-acylglycerol-3-phosphate O-acyltransferase 3	integral component of membrane	Cellular component	-
KIFC1	3833	kinesin family member C1	spindle	Cellular component	-
ANP32E	81611	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E	histone binding	Molecular function	24463511
LPAL2	80350	lipoprotein, Lp(a)-like 2, pseudogene	protein binding	Molecular function	25416956
TGFB1	7040	transforming growth factor, beta 1	hematopoietic progenitor cell differentiation	Biological process	15451575
AHI1	54806	Abelson helper integration site 1	centriole	Cellular component	-
PAK2	5062	p21 protein (Cdc42/Rac)-activated kinase 2	Rac GTPase binding	Molecular function	-
CHD8	57680	chromodomain helicase DNA binding protein 8	p53 binding	Molecular function	-
BTG4	54766	B-cell translocation gene 4	negative regulation of cell proliferation	Biological process	10995567
PPP1R9B	84687	protein phosphatase 1, regulatory subunit 9B	cytoskeleton	Cellular component	-
KDM1A	23028	lysine (K)-specific demethylase 1A	regulation of primitive erythrocyte differentiation	Biological process	-
AKT1	207	v-akt murine thymoma viral oncogene homolog 1	cellular response to epidermal growth factor stimulus	Biological process	-
NTN1	9423	netrin 1	positive regulation of cell proliferation	Biological process	-
DNAJA2	10294	DnaJ (Hsp40) homolog, subfamily A, member 2	membrane	Cellular component	-
TOP1MT	116447	topoisomerase (DNA) I, mitochondrial	chromatin remodeling	Biological process	-
OPN4	94233	opsin 4	11-cis retinal binding	Molecular function	15674244
FYN	2534	FYN proto-oncogene, Src family tyrosine kinase	cellular response to platelet-derived growth factor stimulus	Biological process	-
STC2	8614	stanniocalcin 2	endoplasmic reticulum unfolded protein response	Biological process	-
MAPK8IP3	23162	mitogen-activated protein kinase 8 interacting protein 3	protein localization	Biological process	-
RAB3IP	117177	RAB3A interacting protein	positive regulation of GTPase activity	Biological process	-
SOS1	6654	son of sevenless homolog 1 (Drosophila)	positive regulation of small GTPase mediated signal transduction	Biological process	-
SUN1	23353	Sad1 and UNC84 domain containing 1	intracellular membrane-bounded organelle	Cellular component	-
MYSM1	114803	Myb-like, SWIRM and MPN domains 1	nucleoplasm	Cellular component	-
WNT3A	89780	wingless-type MMTV integration site family, member 3A	post-anal tail morphogenesis	Biological process	-
ANKRD45	339416	ankyrin repeat domain 45	protein binding	Molecular function	25416956
TLR4	7099	toll-like receptor 4	positive regulation of ERK1 and ERK2 cascade	Biological process	-
HPN	3249	hepsin	integral component of membrane	Cellular component	19843851
IKBKB	3551	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	stimulatory C-type lectin receptor signaling pathway	Biological process	-
LNX1	84708	ligand of numb-protein X 1, E3 ubiquitin protein ligase	ubiquitin-protein transferase activity	Molecular function	-
INO80C	125476	INO80 complex subunit C	biological_process	Biological process	-
EIF4EBP2	1979	eukaryotic translation initiation factor 4E binding protein 2	memory	Biological process	-
UQCRFS1	7386	ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1	response to antibiotic	Biological process	-
CDKN2AIP	55602	CDKN2A interacting protein	nucleus	Cellular component	-
NFKBIA	4792	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	cytoplasm	Cellular component	-
CIRBP	1153	cold inducible RNA binding protein	response to cold	Biological process	9151692
FGFR2	2263	fibroblast growth factor receptor 2	regulation of branching involved in prostate gland morphogenesis	Biological process	-
C3AR1	719	complement component 3a receptor 1	phosphatidylinositol phospholipase C activity	Molecular function	8765043
PSMA3	5684	proteasome (prosome, macropain) subunit, alpha type, 3	cellular nitrogen compound metabolic process	Biological process	-
ETS2	2114	v-ets avian erythroblastosis virus E26 oncogene homolog 2	negative regulation of transcription from RNA polymerase II promoter	Biological process	12637547
RAP1A	5906	RAP1A, member of RAS oncogene family	blood coagulation	Biological process	-
KRTAP8-1	337879	keratin associated protein 8-1	intermediate filament	Cellular component	-
PSENEN	55851	presenilin enhancer gamma secretase subunit	Golgi apparatus	Cellular component	15274632
IL1A	3552	interleukin 1, alpha	negative regulation of cell proliferation	Biological process	3493774
PAICS	10606	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase	extracellular exosome	Cellular component	20458337
GRINA	2907	glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)	endoplasmic reticulum calcium ion homeostasis	Biological process	-
TMC2	117532	transmembrane channel-like 2	vestibular reflex	Biological process	-
BICD1	636	bicaudal D homolog 1 (Drosophila)	protein localization to organelle	Biological process	12447383
MED1	5469	mediator complex subunit 1	cellular response to hepatocyte growth factor stimulus	Biological process	-
CASC5	57082	cancer susceptibility candidate 5	protein binding	Molecular function	15231748
GGT5	2687	gamma-glutamyltransferase 5	glutathione biosynthetic process	Biological process	-
TPGS1	91978	tubulin polyglutamylase complex subunit 1	multicellular organismal development	Biological process	-
SRPR	6734	signal recognition particle receptor (docking protein)	gene expression	Biological process	-
ALB	213	albumin	drug binding	Molecular function	10940303
SLC6A8	6535	solute carrier family 6 (neurotransmitter transporter), member 8	integral component of plasma membrane	Cellular component	-
H2AFZ	3015	H2A histone family, member Z	nucleosomal DNA binding	Molecular function	19633671
CAV3	859	caveolin 3	ion channel binding	Molecular function	17060380
C2CD3	26005	C2 calcium-dependent domain containing 3	regulation of proteolysis	Biological process	-
SIAH2	6478	siah E3 ubiquitin protein ligase 2	neuron projection	Cellular component	-
STAT2	6773	signal transducer and activator of transcription 2, 113kDa	DNA binding	Molecular function	-
SNRNP200	23020	small nuclear ribonucleoprotein 200kDa (U5)	gene expression	Biological process	-
TMOD3	29766	tropomodulin 3 (ubiquitous)	erythrocyte development	Biological process	-
AKAP13	11214	A kinase (PRKA) anchor protein 13	nucleus	Cellular component	-
SCN1A	6323	sodium channel, voltage gated, type I alpha subunit	voltage-gated sodium channel activity	Molecular function	10742094
MMP19	4327	matrix metallopeptidase 19	collagen catabolic process	Biological process	-
USP16	10600	ubiquitin specific peptidase 16	cysteine-type endopeptidase activity	Molecular function	17914355
CNNM4	26504	cyclin and CBS domain divalent metal cation transport mediator 4	ion transport	Biological process	-
APEH	327	acylaminoacyl-peptide hydrolase	omega peptidase activity	Molecular function	17241160
STRAP	11171	serine/threonine kinase receptor associated protein	negative regulation of epithelial cell proliferation	Biological process	23687415
TEC	7006	tec protein tyrosine kinase	extrinsic component of cytoplasmic side of plasma membrane	Cellular component	-
GRIN3A	116443	glutamate receptor, ionotropic, N-methyl-D-aspartate 3A	protein phosphatase 2A binding	Molecular function	-
CASK	8573	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	basement membrane	Cellular component	18664494
SFRP4	6424	secreted frizzled-related protein 4	G-protein coupled receptor activity	Molecular function	-
SCD	6319	stearoyl-CoA desaturase (delta-9-desaturase)	endoplasmic reticulum membrane	Cellular component	-
NOMO1	23420	NODAL modulator 1	membrane	Cellular component	19946888
SEH1L	81929	SEH1-like (S. cerevisiae)	mitotic metaphase plate congression	Biological process	17363900
ALOX15	246	arachidonate 15-lipoxygenase	positive regulation of ERK1 and ERK2 cascade	Biological process	21831839
UNC13B	10497	unc-13 homolog B (C. elegans)	signal transduction	Biological process	9607201
PDGFC	56034	platelet derived growth factor C	growth factor activity	Molecular function	-
HIF1A	3091	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	positive regulation of nitric-oxide synthase activity	Biological process	18254728
SYT15	83849	synaptotagmin XV	syntaxin binding	Molecular function	-
SLC19A1	6573	solute carrier family 19 (folate transporter), member 1	water-soluble vitamin metabolic process	Biological process	-
ATP5D	513	ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit	proton-transporting ATPase activity, rotational mechanism	Molecular function	-
NUF2	83540	NUF2, NDC80 kinetochore complex component	molecular_function	Molecular function	-
PPP1R3F	89801	protein phosphatase 1, regulatory subunit 3F	regulation of glycogen (starch) synthase activity	Biological process	21668450
SLC8A1	6546	solute carrier family 8 (sodium/calcium exchanger), member 1	negative regulation of cytosolic calcium ion concentration	Biological process	-
CALM1	801	calmodulin 1 (phosphorylase kinase, delta)	small molecule metabolic process	Biological process	-
IGF2	3481	insulin-like growth factor 2	exocrine pancreas development	Biological process	-
ZP2	7783	zona pellucida glycoprotein 2 (sperm receptor)	extracellular matrix	Cellular component	-
ATP5G1	516	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)	cellular metabolic process	Biological process	-
STX1A	6804	syntaxin 1A (brain)	secretory granule	Cellular component	-
ZNF624	57547	zinc finger protein 624	protein binding	Molecular function	25416956
SYTL4	94121	synaptotagmin-like 4	syntaxin binding	Molecular function	-
PHF8	23133	PHD finger protein 8	chromatin binding	Molecular function	20622854
EDC3	80153	enhancer of mRNA decapping 3	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	Biological process	-
TP53	7157	tumor protein p53	protein complex assembly	Biological process	12915590
NLGN3	54413	neuroligin 3	learning	Biological process	12669065
REEP2	51308	receptor accessory protein 2	integral component of plasma membrane	Cellular component	-
ALDH1A3	220	aldehyde dehydrogenase 1 family, member A3	inner ear morphogenesis	Biological process	-
DEFA5	1670	defensin, alpha 5, Paneth cell-specific	extracellular region	Cellular component	-
SLC20A2	6575	solute carrier family 20 (phosphate transporter), member 2	plasma membrane	Cellular component	-
OR13A1	79290	olfactory receptor, family 13, subfamily A, member 1	olfactory receptor activity	Molecular function	-
DGUOK	1716	deoxyguanosine kinase	ATP binding	Molecular function	-
BMP2KL	347359	BMP2 inducible kinase-like, pseudogene	activation of mitophagy in response to mitochondrial depolarization	Biological process	22020285
KAT5	10524	K(lysine) acetyltransferase 5	androgen receptor binding	Molecular function	15572661
NDUFA11	126328	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa	integral component of membrane	Cellular component	-
UMOD	7369	uromodulin	apical plasma membrane	Cellular component	18025791
SOX8	30812	SRY (sex determining region Y)-box 8	transcription from RNA polymerase II promoter	Biological process	-
RPE	6120	ribulose-5-phosphate-3-epimerase	metal ion binding	Molecular function	20923965
PINK1	65018	PTEN induced putative kinase 1	peptidyl-serine autophosphorylation	Biological process	23626584
KALRN	8997	kalirin, RhoGEF kinase	vesicle-mediated transport	Biological process	9285789
MRPL24	79590	mitochondrial ribosomal protein L24	mitochondrial translation	Biological process	-
PROC	5624	protein C (inactivator of coagulation factors Va and VIIIa)	calcium ion binding	Molecular function	-
CANX	821	calnexin	apolipoprotein binding	Molecular function	-
ATP5A1	498	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle	protein binding	Molecular function	10077593
WNT5A	7474	wingless-type MMTV integration site family, member 5A	response to organic substance	Biological process	17486081
CHUK	1147	conserved helix-loop-helix ubiquitous kinase	striated muscle cell differentiation	Biological process	-
GLB1L	79411	galactosidase, beta 1-like	carbohydrate metabolic process	Biological process	-
TNFAIP8L2	79626	tumor necrosis factor, alpha-induced protein 8-like 2	negative regulation of inflammatory response	Biological process	-
ECE2	9718	endothelin converting enzyme 2	cardioblast differentiation	Biological process	-
PRKAR2B	5577	protein kinase, cAMP-dependent, regulatory, type II, beta	transmembrane transport	Biological process	-
FNDC3A	22862	fibronectin type III domain containing 3A	Sertoli cell development	Biological process	-
TECTA	7007	tectorin alpha	cell-matrix adhesion	Biological process	-
RSG1	79363	REM2 and RAB-like small GTPase 1	regulation of vesicle fusion	Biological process	-
NDUFC2	4718	NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa	respiratory electron transport chain	Biological process	-
CDK16	5127	cyclin-dependent kinase 16	neuron projection development	Biological process	-
ANGPT1	284	angiopoietin 1	sprouting angiogenesis	Biological process	10218485
SPON1	10418	spondin 1, extracellular matrix protein	cell adhesion	Biological process	-
CNTN1	1272	contactin 1	axon guidance	Biological process	-
SLC1A6	6511	solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6	L-aspartate transmembrane transport	Biological process	7791878
GAK	2580	cyclin G associated kinase	intracellular membrane-bounded organelle	Cellular component	-
TGFBR2	7048	transforming growth factor, beta receptor II (70/80kDa)	embryonic cranial skeleton morphogenesis	Biological process	-
SLC25A37	51312	solute carrier family 25 (mitochondrial iron transporter), member 37	iron ion transmembrane transport	Biological process	-
BSND	7809	barttin CLCNK-type chloride channel accessory beta subunit	chloride channel activity	Molecular function	-
SYTL4	94121	synaptotagmin-like 4	neurexin family protein binding	Molecular function	-
PJA2	9867	praja ring finger 2, E3 ubiquitin protein ligase	zinc ion binding	Molecular function	-
GLO1	2739	glyoxalase I	methylglyoxal metabolic process	Biological process	-
HNF1B	6928	HNF1 homeobox B	ureteric bud elongation	Biological process	-
ECT2	1894	epithelial cell transforming 2	protein homodimerization activity	Molecular function	15545273
MBD2	8932	methyl-CpG binding domain protein 2	protein binding	Molecular function	12183469
NDRG1	10397	N-myc downstream regulated 1	recycling endosome membrane	Cellular component	17786215
ZNF354A	6940	zinc finger protein 354A	nucleus	Cellular component	21630459
XRCC4	7518	X-ray repair complementing defective repair in Chinese hamster cells 4	isotype switching	Biological process	-
DIXDC1	85458	DIX domain containing 1	canonical Wnt signaling pathway	Biological process	-
SCNN1B	6338	sodium channel, non voltage gated 1 beta subunit	integral component of plasma membrane	Cellular component	24124190
SH3RF2	153769	SH3 domain containing ring finger 2	phosphatase binding	Molecular function	19389623
RALGPS1	9649	Ral GEF with PH domain and SH3 binding motif 1	regulation of Ral protein signal transduction	Biological process	10747847
NCBP1	4686	nuclear cap binding protein subunit 1, 80kDa	positive regulation of mRNA 3'-end processing	Biological process	9342333
WDR44	54521	WD repeat domain 44	cytosol	Cellular component	-
MCM10	55388	minichromosome maintenance complex component 10	nucleus	Cellular component	-
ADAM17	6868	ADAM metallopeptidase domain 17	T cell differentiation in thymus	Biological process	10433800
BCL2	596	B-cell CLL/lymphoma 2	metanephros development	Biological process	-
PSMA2	5683	proteasome (prosome, macropain) subunit, alpha type, 2	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	Biological process	-
UBE2B	7320	ubiquitin-conjugating enzyme E2B	cellular response to insulin stimulus	Biological process	-
MMP14	4323	matrix metallopeptidase 14 (membrane-inserted)	branching morphogenesis of an epithelial tube	Biological process	-
CHRNA5	1138	cholinergic receptor, nicotinic, alpha 5 (neuronal)	ligand-gated ion channel activity	Molecular function	20438829
OR51B5	282763	olfactory receptor, family 51, subfamily B, member 5	G-protein coupled receptor signaling pathway	Biological process	-
ZNF318	24149	zinc finger protein 318	meiotic cell cycle	Biological process	-
TRIM28	10155	tripartite motif containing 28	embryonic placenta morphogenesis	Biological process	-
BBS2	583	Bardet-Biedl syndrome 2	membrane	Cellular component	-
PHOSPHO2	493911	phosphatase, orphan 2	pyridoxal phosphatase activity	Molecular function	-
CLRN1	7401	clarin 1	lamellipodium	Cellular component	19423712
TLR2	7097	toll-like receptor 2	negative regulation of cell proliferation	Biological process	-
IL6ST	3572	interleukin 6 signal transducer	interleukin-6 receptor binding	Molecular function	12829785
FZD2	2535	frizzled class receptor 2	Wnt-activated receptor activity	Molecular function	-
WNT8B	7479	wingless-type MMTV integration site family, member 8B	cell fate commitment	Biological process	-
FBXL21	26223	F-box and leucine-rich repeat protein 21 (gene/pseudogene)	SCF ubiquitin ligase complex	Cellular component	-
RAD51AP1	10635	RAD51 associated protein 1	single-stranded DNA binding	Molecular function	9396801
HRNR	388697	hornerin	extracellular exosome	Cellular component	21362503
NR2F2	7026	nuclear receptor subfamily 2, group F, member 2	negative regulation of cyclin-dependent protein serine/threonine kinase activity	Biological process	19210544
FOXC2	2303	forkhead box C2	sequence-specific DNA binding transcription factor activity	Molecular function	9169153
GABARAPL3	23766	GABA(A) receptors associated protein like 3, pseudogene	autophagosome assembly	Biological process	-
PICK1	9463	protein interacting with PRKCA 1	postsynaptic membrane	Cellular component	-
RNF146	81847	ring finger protein 146	cytosol	Cellular component	-
MCM2	4171	minichromosome maintenance complex component 2	metal ion binding	Molecular function	-
ITGA3	3675	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	fibronectin binding	Molecular function	-
INTS3	65123	integrator complex subunit 3	protein binding	Molecular function	16239144
IL6R	3570	interleukin 6 receptor	ciliary neurotrophic factor receptor activity	Molecular function	12643274
MRC2	9902	mannose receptor, C type 2	protein binding	Molecular function	7904248
TEF	7008	thyrotrophic embryonic factor	transcription, DNA-templated	Biological process	-
SMG7	9887	SMG7 nonsense mediated mRNA decay factor	nucleus	Cellular component	14636577
PCDHB12	56124	protocadherin beta 12	cell adhesion	Biological process	10380929
CHCHD6	84303	coiled-coil-helix-coiled-coil-helix domain containing 6	mitochondrion	Cellular component	22228767
PTPRT	11122	protein tyrosine phosphatase, receptor type, T	protein tyrosine phosphatase activity	Molecular function	16973135
PLK5	126520	polo-like kinase 5	positive regulation of neuron projection development	Biological process	21245385
CHMP6	79643	charged multivesicular body protein 6	cytosol	Cellular component	-
RAD51D	5892	RAD51 paralog D	single-stranded DNA binding	Molecular function	10871607
COL16A1	1307	collagen, type XVI, alpha 1	integrin activation	Biological process	16754661
HBA2	3040	hemoglobin, alpha 2	blood microparticle	Cellular component	22516433
EARS2	124454	glutamyl-tRNA synthetase 2, mitochondrial	tRNA aminoacylation for protein translation	Biological process	-
GATA4	2626	GATA binding protein 4	nuclear chromatin	Cellular component	-
ANXA2P2	304	annexin A2 pseudogene 2	melanosome	Cellular component	-
WTAP	9589	Wilms tumor 1 associated protein	RNA splicing	Biological process	-
FNIP1	96459	folliculin interacting protein 1	protein binding	Molecular function	17028174
CDH13	1012	cadherin 13	cell junction assembly	Biological process	-
Sep-02	4735	septin 2	nucleus	Cellular component	-
FAM220A	84792	family with sequence similarity 220, member A	nucleus	Cellular component	-
BCL2L13	23786	BCL2-like 13 (apoptosis facilitator)	activation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	11262395
NOTCH2	4853	notch 2	positive regulation of Ras protein signal transduction	Biological process	11306509
TGFB1I1	7041	transforming growth factor beta 1 induced transcript 1	extracellular matrix	Cellular component	20551380
LGI3	203190	leucine-rich repeat LGI family, member 3	cell junction	Cellular component	-
HIF1A	3091	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	protein binding	Molecular function	11292862
IRGM	345611	immunity-related GTPase family, M	hydrolase activity	Molecular function	-
ACADVL	37	acyl-CoA dehydrogenase, very long chain	endoplasmic reticulum unfolded protein response	Biological process	-
LYN	4067	LYN proto-oncogene, Src family tyrosine kinase	negative regulation of B cell proliferation	Biological process	-
RAB8A	4218	RAB8A, member RAS oncogene family	protein kinase binding	Molecular function	-
CSNK1G2	1455	casein kinase 1, gamma 2	endocytosis	Biological process	-
NEK4	6787	NIMA-related kinase 4	manganese ion binding	Molecular function	-
PPP1R3G	648791	protein phosphatase 1, regulatory subunit 3G	cytoplasm	Cellular component	-
BAX	581	BCL2-associated X protein	regulation of protein heterodimerization activity	Biological process	9111042
DUSP16	80824	dual specificity phosphatase 16	nucleoplasm	Cellular component	-
SOD2	6648	superoxide dismutase 2, mitochondrial	intrinsic apoptotic signaling pathway in response to oxidative stress	Biological process	-
SLC1A6	6511	solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6	Golgi apparatus	Cellular component	-
WBSCR17	64409	Williams-Beuren syndrome chromosome region 17	metal ion binding	Molecular function	-
CYP17A1	1586	cytochrome P450, family 17, subfamily A, polypeptide 1	ovulation	Biological process	-
RBM3	5935	RNA binding motif (RNP1, RRM) protein 3	regulation of translation	Biological process	-
RUNX1	861	runt-related transcription factor 1	regulatory region DNA binding	Molecular function	21873977
AGPAT4	56895	1-acylglycerol-3-phosphate O-acyltransferase 4	CDP-diacylglycerol biosynthetic process	Biological process	-
HELZ	9931	helicase with zinc finger	metal ion binding	Molecular function	-
OR52A4P	390053	olfactory receptor, family 52, subfamily A, member 4, pseudogene	integral component of membrane	Cellular component	-
SGCZ	137868	sarcoglycan, zeta	muscle cell cellular homeostasis	Biological process	17438352
SLC20A1	6574	solute carrier family 20 (phosphate transporter), member 1	integral component of plasma membrane	Cellular component	8041748
RASGRP1	10125	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	positive regulation of interferon-gamma secretion	Biological process	19933860
DDT	1652	D-dopachrome tautomerase	melanin biosynthetic process	Biological process	-
SPICE1	152185	spindle and centriole associated protein 1	cell division	Biological process	-
PEX3	8504	peroxisomal biogenesis factor 3	lipid binding	Molecular function	19715730
BMP4	652	bone morphogenetic protein 4	endocardial cushion development	Biological process	18076106
VASP	7408	vasodilator-stimulated phosphoprotein	actin polymerization or depolymerization	Biological process	-
CCDC62	84660	coiled-coil domain containing 62	ligand-dependent nuclear receptor transcription coactivator activity	Molecular function	19126643
PRPF19	27339	pre-mRNA processing factor 19	cellular protein localization	Biological process	18263876
RPL36	25873	ribosomal protein L36	membrane	Cellular component	19946888
FOXP2	93986	forkhead box P2	putamen development	Biological process	11872605
SHC4	399694	SHC (Src homology 2 domain containing) family, member 4	stem cell differentiation	Biological process	-
MYOD1	4654	myogenic differentiation 1	transcription factor binding	Molecular function	-
OR7C1	26664	olfactory receptor, family 7, subfamily C, member 1	G-protein coupled receptor signaling pathway	Biological process	-
BTK	695	Bruton agammaglobulinemia tyrosine kinase	B cell activation	Biological process	19290921
CHRM2	1129	cholinergic receptor, muscarinic 2	sensory perception of chemical stimulus	Biological process	-
CCDC30	728621	coiled-coil domain containing 30	extracellular exosome	Cellular component	23376485
MSX1	4487	msh homeobox 1	pituitary gland development	Biological process	-
SH2B1	25970	SH2B adaptor protein 1	membrane	Cellular component	-
BIN2	51411	bridging integrator 2	podosome assembly	Biological process	23285027
COL5A2	1290	collagen, type V, alpha 2	endoplasmic reticulum lumen	Cellular component	-
PTPRU	10076	protein tyrosine phosphatase, receptor type, U	organ regeneration	Biological process	-
CPEB1	64506	cytoplasmic polyadenylation element binding protein 1	synaptonemal complex assembly	Biological process	-
DLG1	1739	discs, large homolog 1 (Drosophila)	hard palate development	Biological process	-
PSME1	5720	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)	small molecule metabolic process	Biological process	-
RIPK3	11035	receptor-interacting serine-threonine kinase 3	innate immune response	Biological process	-
PSMB10	5699	proteasome (prosome, macropain) subunit, beta type, 10	regulation of cellular amino acid metabolic process	Biological process	-
PROM1	8842	prominin 1	photoreceptor outer segment	Cellular component	-
OLFM4	10562	olfactomedin 4	extracellular space	Cellular component	16566923
PTPRK	5796	protein tyrosine phosphatase, receptor type, K	beta-catenin binding	Molecular function	8663237
AURKAIP1	54998	aurora kinase A interacting protein 1	mitochondrial translation	Biological process	-
PTCH1	5727	patched 1	protein processing	Biological process	-
NFKB2	4791	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	nucleoplasm	Cellular component	-
SEC61A2	55176	Sec61 alpha 2 subunit (S. cerevisiae)	antigen processing and presentation of exogenous peptide antigen via MHC class I	Biological process	-
NRROS	375387	negative regulator of reactive oxygen species	inflammatory response	Biological process	-
EFCAB10	100130771	EF-hand calcium binding domain 10	calcium ion binding	Molecular function	-
ALOX12	239	arachidonate 12-lipoxygenase	lipoxin A4 biosynthetic process	Biological process	8250832
HNRNPDL	9987	heterogeneous nuclear ribonucleoprotein D-like	poly(A) RNA binding	Molecular function	22658674
GABRG1	2565	gamma-aminobutyric acid (GABA) A receptor, gamma 1	cell junction	Cellular component	-
CNR1	1268	cannabinoid receptor 1 (brain)	negative regulation of blood pressure	Biological process	-
WNT11	7481	wingless-type MMTV integration site family, member 11	neuroendocrine cell differentiation	Biological process	20219091
ANG	283	angiogenin, ribonuclease, RNase A family, 5	endonuclease activity	Molecular function	10103013
MPP2	4355	membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)	signal transduction	Biological process	7590743
TNFSF11	8600	tumor necrosis factor (ligand) superfamily, member 11	positive regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	-
ERLIN2	11160	ER lipid raft associated 2	endoplasmic reticulum	Cellular component	-
PRAMEF6	440561	PRAME family member 6	negative regulation of cell differentiation	Biological process	-
IL1RL1	9173	interleukin 1 receptor-like 1	intracellular signal transduction	Biological process	1482686
ISL1	3670	ISL LIM homeobox 1	pharyngeal system development	Biological process	-
XBP1	7494	X-box binding protein 1	endothelial cell proliferation	Biological process	23529610
EXOC4	60412	exocyst complex component 4	vesicle docking involved in exocytosis	Biological process	-
Mar-09	92979	membrane-associated ring finger (C3HC4) 9	trans-Golgi network	Cellular component	14722266
NRG1	3084	neuregulin 1	positive regulation of protein targeting to mitochondrion	Biological process	24270810
SLC22A18	5002	solute carrier family 22, member 18	nuclear envelope	Cellular component	16314844
FLNA	2316	filamin A, alpha	actin crosslink formation	Biological process	10051605
PDGFA	5154	platelet-derived growth factor alpha polypeptide	response to hypoxia	Biological process	-
ATXN3	4287	ataxin 3	actin cytoskeleton organization	Biological process	20637808
MYO7A	4647	myosin VIIA	sensory perception of light stimulus	Biological process	11398101
INSR	3643	insulin receptor	insulin-activated receptor activity	Molecular function	6849137
CD2	914	CD2 molecule	receptor activity	Molecular function	7544493
LRRC8B	23507	leucine rich repeat containing 8 family, member B	integral component of membrane	Cellular component	-
SCIN	85477	scinderin	extracellular exosome	Cellular component	19056867
CTNND1	1500	catenin (cadherin-associated protein), delta 1	vascular endothelial growth factor receptor signaling pathway	Biological process	-
TNR	7143	tenascin R	axon guidance	Biological process	8940128
HOXB8	3218	homeobox B8	dorsal spinal cord development	Biological process	-
PTPMT1	114971	protein tyrosine phosphatase, mitochondrial 1	nucleus	Cellular component	21630459
ENTPD2	954	ectonucleoside triphosphate diphosphohydrolase 2	nucleoside-diphosphatase activity	Molecular function	-
TFDP1	7027	transcription factor Dp-1	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
ACE	1636	angiotensin I converting enzyme	tripeptidyl-peptidase activity	Molecular function	2983326
SLC13A4	26266	solute carrier family 13 (sodium/sulfate symporter), member 4	plasma membrane	Cellular component	-
MYH10	4628	myosin, heavy chain 10, non-muscle	growth cone	Cellular component	-
NCOR2	9612	nuclear receptor corepressor 2	histone deacetylase binding	Molecular function	11804585
CAPS	828	calcyphosine	activation of mitophagy in response to mitochondrial depolarization	Biological process	22020285
TNC	3371	tenascin C	positive regulation of cell proliferation	Biological process	-
SLTM	79811	SAFB-like, transcription modulator	transcription, DNA-templated	Biological process	-
ANXA9	8416	annexin A9	calcium ion binding	Molecular function	-
HOXA1	3198	homeobox A1	optokinetic behavior	Biological process	16155570
ANXA7	310	annexin A7	cell proliferation	Biological process	-
FGD6	55785	FYVE, RhoGEF and PH domain containing 6	small GTPase binding	Molecular function	-
APEX2	27301	APEX nuclease (apurinic/apyrimidinic endonuclease) 2	DNA recombination	Biological process	-
GPR63	81491	G protein-coupled receptor 63	biological_process	Biological process	-
NKX3-1	4824	NK3 homeobox 1	estrogen receptor binding	Molecular function	18794125
UBC	7316	ubiquitin C	neurotrophin TRK receptor signaling pathway	Biological process	-
NUDT1	4521	nudix (nucleoside diphosphate linked moiety X)-type motif 1	metal ion binding	Molecular function	-
CD70	970	CD70 molecule	extracellular exosome	Cellular component	20458337
RAPH1	65059	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1	lamellipodium	Cellular component	-
MKL1	57591	megakaryoblastic leukemia (translocation) 1	cytosol	Cellular component	-
ADSS	159	adenylosuccinate synthase	cellular response to electrical stimulus	Biological process	-
TRAM1	23471	translocation associated membrane protein 1	translation	Biological process	-
KRT27	342574	keratin 27, type I	hair follicle morphogenesis	Biological process	-
SOX14	8403	SRY (sex determining region Y)-box 14	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
CST3	1471	cystatin C	defense response	Biological process	6203523
FGF1	2246	fibroblast growth factor 1 (acidic)	positive regulation of cell proliferation	Biological process	18187602
HIST1H3J	8356	histone cluster 1, H3j	chromatin organization	Biological process	-
PLEKHA1	59338	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	negative regulation of protein kinase B signaling	Biological process	14516276
AGTR2	186	angiotensin II receptor, type 2	positive regulation of extrinsic apoptotic signaling pathway	Biological process	10406457
WWOX	51741	WW domain containing oxidoreductase	coenzyme binding	Molecular function	10786676
MAP2K7	5609	mitogen-activated protein kinase kinase 7	toll-like receptor TLR1:TLR2 signaling pathway	Biological process	-
GJA5	2702	gap junction protein, alpha 5, 40kDa	atrial ventricular junction remodeling	Biological process	-
RAD17	5884	RAD17 homolog (S. pombe)	chromosome, telomeric region	Cellular component	15149599
CYTH1	9267	cytohesin 1	lipid binding	Molecular function	-
CALCB	797	calcitonin-related polypeptide beta	neuropeptide hormone activity	Molecular function	2985435
AGTR1	185	angiotensin II receptor, type 1	regulation of renal sodium excretion	Biological process	17159080
KIAA0430	9665	KIAA0430	RNA binding	Molecular function	-
IL10	3586	interleukin 10	leukocyte chemotaxis	Biological process	9405662
LIN7A	8825	lin-7 homolog A (C. elegans)	plasma membrane	Cellular component	-
TNF	7124	tumor necrosis factor	positive regulation of protein transport	Biological process	15310755
BBS9	27241	Bardet-Biedl syndrome 9	fat cell differentiation	Biological process	-
CPOX	1371	coproporphyrinogen oxidase	mitochondrion	Cellular component	-
FKBP1A	2280	FK506 binding protein 1A, 12kDa	cytosol	Cellular component	-
ZP3	7784	zona pellucida glycoprotein 3 (sperm receptor)	positive regulation of antral ovarian follicle growth	Biological process	-
AMOT	154796	angiomotin	COP9 signalosome	Cellular component	18850735
ZFAND5	7763	zinc finger, AN1-type domain 5	face development	Biological process	-
TSC1	7248	tuberous sclerosis 1	response to insulin	Biological process	16996505
NCOA1	8648	nuclear receptor coactivator 1	histone acetyltransferase activity	Molecular function	-
TSPY2	64591	testis specific protein, Y-linked 2	cytoplasm	Cellular component	-
XG	7499	Xg blood group	molecular_function	Molecular function	-
PIK3CA	5290	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	phosphatidylinositol 3-kinase complex, class IA	Cellular component	22402981
CASK	8573	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	cytoplasm	Cellular component	18664494
CCDC13	152206	coiled-coil domain containing 13	cell projection organization	Biological process	-
SETD6	79918	SET domain containing 6	nucleoplasm	Cellular component	-
RBFA	79863	ribosome binding factor A (putative)	rRNA processing	Biological process	-
NRIP1	8204	nuclear receptor interacting protein 1	transcription corepressor activity	Molecular function	10364267
PNPLA3	80339	patatin-like phospholipase domain containing 3	phospholipid metabolic process	Biological process	-
ARID3B	10620	AT rich interactive domain 3B (BRIGHT-like)	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
CRHR1	1394	corticotropin releasing hormone receptor 1	behavioral response to cocaine	Biological process	-
MAK	4117	male germ cell-associated kinase	regulation of cell cycle	Biological process	-
AXL	558	AXL receptor tyrosine kinase	viral entry into host cell	Biological process	21047970
ZNF274	10782	zinc finger protein 274	sequence-specific DNA binding transcription factor activity	Molecular function	10777669
TNF	7124	tumor necrosis factor	necroptotic signaling pathway	Biological process	11101870
CLASP1	23332	cytoplasmic linker associated protein 1	cytoplasmic microtubule	Cellular component	11290329
OR4N5	390437	olfactory receptor, family 4, subfamily N, member 5	G-protein coupled receptor activity	Molecular function	-
DDX19A	55308	DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A	biological_process	Biological process	-
LATS1	9113	large tumor suppressor kinase 1	magnesium ion binding	Molecular function	10518011
ADGRL1	22859	adhesion G protein-coupled receptor L1	cell adhesion molecule binding	Molecular function	-
NDUFS7	374291	NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)	NADH dehydrogenase (ubiquinone) activity	Molecular function	9878551
ACTN1	87	actinin, alpha 1	actin filament bundle assembly	Biological process	-
ATP11C	286410	ATPase, class VI, type 11C	protein binding	Molecular function	21914794
CNDP2	55748	CNDP dipeptidase 2 (metallopeptidase M20 family)	metallopeptidase activity	Molecular function	-
ZNF681	148213	zinc finger protein 681	regulation of transcription, DNA-templated	Biological process	-
PARP4	143	poly (ADP-ribose) polymerase family, member 4	DNA binding	Molecular function	10100603
NTF3	4908	neurotrophin 3	smooth muscle cell differentiation	Biological process	-
GNAZ	2781	guanine nucleotide binding protein (G protein), alpha z polypeptide	GTP binding	Molecular function	-
DOCK2	1794	dedicator of cytokinesis 2	alpha-beta T cell proliferation	Biological process	-
RPGR	6103	retinitis pigmentosa GTPase regulator	intraciliary transport	Biological process	-
COPS4	51138	COP9 signalosome subunit 4	protein deneddylation	Biological process	21102408
RAF1	5894	Raf-1 proto-oncogene, serine/threonine kinase	protein binding	Molecular function	10433554
MME	4311	membrane metallo-endopeptidase	axon	Cellular component	-
IGHA1	3493	immunoglobulin heavy constant alpha 1	extracellular region	Cellular component	-
TEC	7006	tec protein tyrosine kinase	protein binding	Molecular function	10518561
SNX29	92017	sorting nexin 29	extracellular exosome	Cellular component	23376485
REEP3	221035	receptor accessory protein 3	mitotic nuclear division	Biological process	-
OR6B1	135946	olfactory receptor, family 6, subfamily B, member 1	sensory perception of smell	Biological process	-
TH	7054	tyrosine hydroxylase	enzyme binding	Molecular function	19703902
HSPA12A	259217	heat shock 70kDa protein 12A	biological_process	Biological process	-
ORC5	5001	origin recognition complex, subunit 5	DNA replication initiation	Biological process	9765232
GATAD2B	57459	GATA zinc finger domain containing 2B	nuclear speck	Cellular component	-
GSK3B	2932	glycogen synthase kinase 3 beta	integrin binding	Molecular function	-
CDC27	996	cell division cycle 27	metaphase/anaphase transition of mitotic cell cycle	Biological process	7736578
TCF7	6932	transcription factor 7 (T-cell specific, HMG-box)	embryonic genitalia morphogenesis	Biological process	-
KIFAP3	22920	kinesin-associated protein 3	Golgi apparatus	Cellular component	-
NOS1	4842	nitric oxide synthase 1 (neuronal)	sarcolemma	Cellular component	7545544
OR2T27	403239	olfactory receptor, family 2, subfamily T, member 27	G-protein coupled receptor activity	Molecular function	-
OR52N2	390077	olfactory receptor, family 52, subfamily N, member 2	G-protein coupled receptor activity	Molecular function	-
NME2	4831	NME/NM23 nucleoside diphosphate kinase 2	focal adhesion	Cellular component	11919189
MRPL46	26589	mitochondrial ribosomal protein L46	biological_process	Biological process	-
HEXIM2	124790	hexamethylene bis-acetamide inducible 2	snRNA binding	Molecular function	15713662
ZP3	7784	zona pellucida glycoprotein 3 (sperm receptor)	positive regulation of interleukin-4 production	Biological process	-
GJB1	2705	gap junction protein, beta 1, 32kDa	cell-cell signaling	Biological process	8266101
HMGB4	127540	high mobility group box 4	DNA binding	Molecular function	-
TDRD12	91646	tudor domain containing 12	regulation of gene expression	Biological process	-
LMO3	55885	LIM domain only 3 (rhombotin-like 2)	negative regulation of ERK1 and ERK2 cascade	Biological process	23823477
SP100	6672	SP100 nuclear antigen	response to interferon-gamma	Biological process	8810287
FGR	2268	FGR proto-oncogene, Src family tyrosine kinase	regulation of cell shape	Biological process	-
RPL37	6167	ribosomal protein L37	RNA binding	Molecular function	7545944
HLA-B	3106	major histocompatibility complex, class I, B	peptide antigen binding	Molecular function	-
CFLAR	8837	CASP8 and FADD-like apoptosis regulator	skeletal muscle tissue regeneration	Biological process	-
CDK5R1	8851	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	ephrin receptor binding	Molecular function	-
CHTOP	26097	chromatin target of PRMT1	transcription export complex	Cellular component	23299939
IGFBP7	3490	insulin-like growth factor binding protein 7	inner ear development	Biological process	-
WWTR1	25937	WW domain containing transcription regulator 1	protein binding	Molecular function	16099986
KCNQ1	3784	potassium channel, voltage gated KQT-like subfamily Q, member 1	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	Molecular function	8528244
GRIN2A	2903	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	response to wounding	Biological process	-
HRAS	3265	Harvey rat sarcoma viral oncogene homolog	positive regulation of DNA replication	Biological process	9765203
TXNRD3	114112	thioredoxin reductase 3	multicellular organismal development	Biological process	-
IFNG	3458	interferon, gamma	CD8-positive, alpha-beta T cell differentiation involved in immune response	Biological process	-
PLAUR	5329	plasminogen activator, urokinase receptor	endoplasmic reticulum lumen	Cellular component	-
TAS2R42	353164	taste receptor, type 2, member 42	bitter taste receptor activity	Molecular function	20022913
LITAF	9516	lipopolysaccharide-induced TNF factor	negative regulation of NF-kappaB import into nucleus	Biological process	-
MAP4K3	8491	mitogen-activated protein kinase kinase kinase kinase 3	response to UV	Biological process	9275185
TGFB3	7043	transforming growth factor, beta 3	salivary gland morphogenesis	Biological process	18080134
TRAF5	7188	TNF receptor-associated factor 5	positive regulation of cell proliferation	Biological process	-
SSC5D	284297	scavenger receptor cysteine rich family, 5 domains	negative regulation of interleukin-8 secretion	Biological process	-
PSMA2	5683	proteasome (prosome, macropain) subunit, alpha type, 2	response to virus	Biological process	16548883
ASF1B	55723	anti-silencing function 1B histone chaperone	multicellular organismal development	Biological process	-
TMEM63C	57156	transmembrane protein 63C	cation transmembrane transport	Biological process	24503647
ERVK-6	64006	endogenous retrovirus group K, member 6	integral component of membrane	Cellular component	-
NEK4	6787	NIMA-related kinase 4	signal transduction by protein phosphorylation	Biological process	-
SLC26A4	5172	solute carrier family 26 (anion exchanger), member 4	chloride transmembrane transport	Biological process	-
PKNOX1	5316	PBX/knotted 1 homeobox 1	protein heterodimerization activity	Molecular function	-
STAU1	6780	staufen double-stranded RNA binding protein 1	intracellular mRNA localization	Biological process	-
DSEL	92126	dermatan sulfate epimerase-like	Golgi membrane	Cellular component	-
CCL4	6351	chemokine (C-C motif) ligand 4	extracellular region	Cellular component	-
SLC19A1	6573	solute carrier family 19 (folate transporter), member 1	membrane	Cellular component	8276792
CREB3L4	148327	cAMP responsive element binding protein 3-like 4	Golgi membrane	Cellular component	-
THPO	7066	thrombopoietin	myeloid cell differentiation	Biological process	-
TMIE	259236	transmembrane inner ear	inner ear morphogenesis	Biological process	-
METAP1D	254042	methionyl aminopeptidase type 1D (mitochondrial)	N-terminal protein amino acid modification	Biological process	14532271
MTM1	4534	myotubularin 1	filopodium	Cellular component	12118066
AGO2	27161	argonaute RISC catalytic component 2	core promoter binding	Molecular function	25336585
AVPR1B	553	arginine vasopressin receptor 1B	endosome	Cellular component	10858434
ERI1	90459	exoribonuclease 1	DNA catabolic process, exonucleolytic	Biological process	-
APOB	338	apolipoprotein B	very-low-density lipoprotein particle	Cellular component	15308631
SMAD3	4088	SMAD family member 3	regulation of transforming growth factor beta receptor signaling pathway	Biological process	8774881
DYNC1LI1	51143	dynein, cytoplasmic 1, light intermediate chain 1	centrosome	Cellular component	-
THRA	7067	thyroid hormone receptor, alpha	protein binding	Molecular function	10866662
GRN	2896	granulin	intracellular membrane-bounded organelle	Cellular component	-
CD300A	11314	CD300a molecule	negative regulation of mast cell degranulation	Biological process	16339535
IFT46	56912	intraflagellar transport 46	intraciliary transport	Biological process	-
GAL3ST1	9514	galactose-3-O-sulfotransferase 1	Golgi membrane	Cellular component	-
GSK3B	2932	glycogen synthase kinase 3 beta	positive regulation of canonical Wnt signaling pathway	Biological process	-
CTTN	2017	cortactin	lamellipodium organization	Biological process	-
RPS17	6218	ribosomal protein S17	viral life cycle	Biological process	-
DAB2IP	153090	DAB2 interacting protein	regulation of growth	Biological process	-
NDUFA9	4704	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa	mitochondrial inner membrane	Cellular component	-
ANO8	57719	anoctamin 8	integral component of membrane	Cellular component	-
IL12A	3592	interleukin 12A	negative regulation of interleukin-17 production	Biological process	16482511
MYH10	4628	myosin, heavy chain 10, non-muscle	cardiac myofibril assembly	Biological process	-
TMEM237	65062	transmembrane protein 237	regulation of Wnt signaling pathway	Biological process	22152675
AP1S3	130340	adaptor-related protein complex 1, sigma 3 subunit	protein transporter activity	Molecular function	-
CD36	948	CD36 molecule (thrombospondin receptor)	defense response to Gram-positive bacterium	Biological process	-
PDGFB	5155	platelet-derived growth factor beta polypeptide	fibroblast growth factor receptor signaling pathway	Biological process	-
MAPK1	5594	mitogen-activated protein kinase 1	T cell receptor signaling pathway	Biological process	-
ALG9	79796	ALG9, alpha-1,2-mannosyltransferase	dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity	Molecular function	-
NARFL	64428	nuclear prelamin A recognition factor-like	small molecule metabolic process	Biological process	-
NUP62	23636	nucleoporin 62kDa	transcription, DNA-templated	Biological process	-
HSP90B2P	7190	heat shock protein 90kDa beta (Grp94), member 2, pseudogene	response to stress	Biological process	-
CSNK2B	1460	casein kinase 2, beta polypeptide	mitotic cell cycle	Biological process	-
RAB11FIP1	80223	RAB11 family interacting protein 1 (class I)	negative regulation of adiponectin secretion	Biological process	24040321
OR4E2	26686	olfactory receptor, family 4, subfamily E, member 2	transmembrane signaling receptor activity	Molecular function	-
DIP2C	22982	DIP2 disco-interacting protein 2 homolog C (Drosophila)	transcription factor binding	Molecular function	-
RPL9	6133	ribosomal protein L9	cytoplasm	Cellular component	-
MAFF	23764	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F	nucleoplasm	Cellular component	-
MAFG	4097	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G	regulation of cell proliferation	Biological process	-
TAF1L	138474	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like	histone acetylation	Biological process	12217962
ACTC1	70	actin, alpha, cardiac muscle 1	lamellipodium	Cellular component	-
NOTCH1	4851	notch 1	endocardial cushion morphogenesis	Biological process	-
RPL7A	6130	ribosomal protein L7a	SRP-dependent cotranslational protein targeting to membrane	Biological process	-
JUNB	3726	jun B proto-oncogene	DNA binding	Molecular function	10764760
HOXD13	3239	homeobox D13	regulation of branching involved in prostate gland morphogenesis	Biological process	-
ARHGEF10L	55160	Rho guanine nucleotide exchange factor (GEF) 10-like	Rho guanyl-nucleotide exchange factor activity	Molecular function	-
PLK1	5347	polo-like kinase 1	microtubule bundle formation	Biological process	12939256
IL1RN	3557	interleukin 1 receptor antagonist	cytokine-mediated signaling pathway	Biological process	-
ATRX	546	alpha thalassemia/mental retardation syndrome X-linked	DNA binding	Molecular function	-
GLB1L	79411	galactosidase, beta 1-like	beta-galactosidase activity	Molecular function	-
NCOA1	8648	nuclear receptor coactivator 1	nucleus	Cellular component	-
PCDHB10	56126	protocadherin beta 10	plasma membrane	Cellular component	-
APPL1	26060	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	cytosol	Cellular component	17848569
PKP4	8502	plakophilin 4	cell-cell contact zone	Cellular component	22965878
GSK3B	2932	glycogen synthase kinase 3 beta	negative regulation of canonical Wnt signaling pathway	Biological process	19366350
AVPR1A	552	arginine vasopressin receptor 1A	positive regulation of cell growth	Biological process	-
AHNAK	79026	AHNAK nucleoprotein	extracellular exosome	Cellular component	19056867
PM20D2	135293	peptidase M20 domain containing 2	hydrolase activity	Molecular function	-
CHST11	50515	carbohydrate (chondroitin 4) sulfotransferase 11	post-embryonic development	Biological process	-
BCKDHA	593	branched chain keto acid dehydrogenase E1, alpha polypeptide	mitochondrial alpha-ketoglutarate dehydrogenase complex	Cellular component	7883996
CARD16	114769	caspase recruitment domain family, member 16	regulation of apoptotic process	Biological process	-
CNTN2	6900	contactin 2 (axonal)	presynaptic membrane organization	Biological process	23518707
KAT2A	2648	K(lysine) acetyltransferase 2A	regulation of mitochondrion degradation	Biological process	24912190
ERVK-6	64006	endogenous retrovirus group K, member 6	mRNA transport	Biological process	-
IGFBP5	3488	insulin-like growth factor binding protein 5	extracellular space	Cellular component	-
ADSL	158	adenylosuccinate lyase	protein tetramerization	Biological process	16973378
DDIT3	1649	DNA-damage-inducible transcript 3	transcription regulatory region sequence-specific DNA binding	Molecular function	24939851
NSD1	64324	nuclear receptor binding SET domain protein 1	histone H3-K36 methylation	Biological process	-
APOA2	336	apolipoprotein A-II	acute inflammatory response	Biological process	-
ATAT1	79969	alpha tubulin acetyltransferase 1	focal adhesion	Cellular component	-
NME3	4832	NME/NM23 nucleoside diphosphate kinase 3	nucleoside triphosphate biosynthetic process	Biological process	-
NEDD4	4734	neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase	ubiquitin ligase complex	Cellular component	-
AKAP17A	8227	A kinase (PRKA) anchor protein 17A	B cell activation	Biological process	1438229
MLXIPL	51085	MLX interacting protein-like	cellular response to carbohydrate stimulus	Biological process	-
PPP1R15A	23645	protein phosphatase 1, regulatory subunit 15A	cellular response to DNA damage stimulus	Biological process	9153226
CYP1A1	1543	cytochrome P450, family 1, subfamily A, polypeptide 1	hepatocyte differentiation	Biological process	-
ZFYVE21	79038	zinc finger, FYVE domain containing 21	protein binding	Molecular function	25416956
NIF3L1	60491	NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)	nucleus	Cellular component	-
RCL1	10171	RNA terminal phosphate cyclase-like 1	RNA-3'-phosphate cyclase activity	Molecular function	-
NDEL1	81565	nudE neurodevelopment protein 1-like 1	nucleolus	Cellular component	-
UBE2O	63893	ubiquitin-conjugating enzyme E2O	poly(A) RNA binding	Molecular function	22681889
GALNT3	2591	polypeptide N-acetylgalactosaminyltransferase 3	Golgi cisterna membrane	Cellular component	-
DOCK4	9732	dedicator of cytokinesis 4	cell chemotaxis	Biological process	20679435
YWHAB	7529	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta	cytosol	Cellular component	-
PDXK	8566	pyridoxal (pyridoxine, vitamin B6) kinase	ATP binding	Molecular function	16600635
HOOK3	84376	hook microtubule-tethering protein 3	negative regulation of neurogenesis	Biological process	-
HOXA2	3199	homeobox A2	cell fate determination	Biological process	-
ISL2	64843	ISL LIM homeobox 2	regulation of transcription, DNA-templated	Biological process	-
ZBTB24	9841	zinc finger and BTB domain containing 24	hematopoietic progenitor cell differentiation	Biological process	-
PMAIP1	5366	phorbol-12-myristate-13-acetate-induced protein 1	cellular response to hypoxia	Biological process	14699081
NF1	4763	neurofibromin 1	smooth muscle tissue development	Biological process	-
P2RX6	9127	purinergic receptor P2X, ligand gated ion channel, 6	ion transmembrane transport	Biological process	-
PMS2P1	5379	postmeiotic segregation increased 2 pseudogene 1	kinase activity	Molecular function	-
USH1C	10083	Usher syndrome 1C (autosomal recessive, severe)	cytoskeleton	Cellular component	-
ASF1A	25842	anti-silencing function 1A histone chaperone	protein binding	Molecular function	19862764
CREB1	1385	cAMP responsive element binding protein 1	positive regulation of osteoclast differentiation	Biological process	-
GFM2	84340	G elongation factor, mitochondrial 2	organelle organization	Biological process	-
ACVR1B	91	activin A receptor, type IB	development of primary female sexual characteristics	Biological process	-
ADA	100	adenosine deaminase	plasma membrane	Cellular component	-
NEUROD2	4761	neuronal differentiation 2	nervous system development	Biological process	8816493
IGHG1	3500	immunoglobulin heavy constant gamma 1 (G1m marker)	extracellular exosome	Cellular component	23376485
KLHL17	339451	kelch-like family member 17	actin cytoskeleton organization	Biological process	-
NSMCE2	286053	non-SMC element 2, MMS21 homolog (S. cerevisiae)	protein binding	Molecular function	18086888
MYL6	4637	myosin, light chain 6, alkali, smooth muscle and non-muscle	calcium ion binding	Molecular function	-
C1QTNF2	114898	C1q and tumor necrosis factor related protein 2	receptor binding	Molecular function	-
VTI1B	10490	vesicle transport through interaction with t-SNAREs 1B	intracellular membrane-bounded organelle	Cellular component	-
LLGL2	3993	lethal giant larvae homolog 2 (Drosophila)	protein binding	Molecular function	12725730
DNM1L	10059	dynamin 1-like	lipid binding	Molecular function	-
DTL	51514	denticleless E3 ubiquitin protein ligase homolog (Drosophila)	cellular response to DNA damage stimulus	Biological process	20129063
HIST2H4A	8370	histone cluster 2, H4a	poly(A) RNA binding	Molecular function	22658674
FITM1	161247	fat storage-inducing transmembrane protein 1	phospholipid biosynthetic process	Biological process	-
SKAP1	8631	src kinase associated phosphoprotein 1	positive regulation of signal transduction	Biological process	9195899
PICALM	8301	phosphatidylinositol binding clathrin assembly protein	cell proliferation	Biological process	22952941
CPEB4	80315	cytoplasmic polyadenylation element binding protein 4	ionotropic glutamate receptor signaling pathway	Biological process	-
NUDT22	84304	nudix (nucleoside diphosphate linked moiety X)-type motif 22	hydrolase activity	Molecular function	-
OR4C46	119749	olfactory receptor, family 4, subfamily C, member 46	G-protein coupled receptor signaling pathway	Biological process	-
ITGB2	3689	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	integrin-mediated signaling pathway	Biological process	12885943
RFC1	5981	replication factor C (activator 1) 1, 145kDa	error-prone translesion synthesis	Biological process	-
TGFB2	7042	transforming growth factor, beta 2	generation of neurons	Biological process	15944186
DLAT	1737	dihydrolipoamide S-acetyltransferase	small molecule metabolic process	Biological process	-
LZTFL1	54585	leucine zipper transcription factor-like 1	negative regulation of protein localization to ciliary membrane	Biological process	22072986
CLLU1	574028	chronic lymphocytic leukemia up-regulated 1	cytoplasm	Cellular component	-
ALAS2	212	5'-aminolevulinate synthase 2	protoporphyrinogen IX biosynthetic process	Biological process	-
CTSS	1520	cathepsin S	extracellular region	Cellular component	-
HNRNPM	4670	heterogeneous nuclear ribonucleoprotein M	integral component of plasma membrane	Cellular component	8088785
HIP1	3092	huntingtin interacting protein 1	clathrin binding	Molecular function	11577110
HYAL2	8692	hyaluronoglucosaminidase 2	transforming growth factor beta binding	Molecular function	-
HLA-DRB4	3126	major histocompatibility complex, class II, DR beta 4	T cell receptor signaling pathway	Biological process	-
EGFR	1956	epidermal growth factor receptor	positive regulation of DNA replication	Biological process	17115032
CHUK	1147	conserved helix-loop-helix ubiquitous kinase	lactation	Biological process	-
HSF1	3297	heat shock transcription factor 1	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	8926278
PSMD12	5718	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	positive regulation of canonical Wnt signaling pathway	Biological process	-
DMGDH	29958	dimethylglycine dehydrogenase	poly(A) RNA binding	Molecular function	22658674
IL2RA	3559	interleukin 2 receptor, alpha	cell proliferation	Biological process	2983318
ZMIZ1	57178	zinc finger, MIZ-type containing 1	nuclear speck	Cellular component	-
POLR2E	5434	polymerase (RNA) II (DNA directed) polypeptide E, 25kDa	transcription from RNA polymerase II promoter	Biological process	-
CYP1A2	1544	cytochrome P450, family 1, subfamily A, polypeptide 2	monoterpenoid metabolic process	Biological process	16401082
MAPK8	5599	mitogen-activated protein kinase 8	stress-activated MAPK cascade	Biological process	-
PATE3	100169851	prostate and testis expressed 3	extracellular region	Cellular component	-
SYMPK	8189	symplekin	protein binding	Molecular function	18688255
RTCB	51493	RNA 2',3'-cyclic phosphate and 5'-OH ligase	nucleus	Cellular component	24608264
TBX2	6909	T-box 2	developmental growth involved in morphogenesis	Biological process	-
FAM126A	84668	family with sequence similarity 126, member A	biological_process	Biological process	-
MBNL1	4154	muscleblind-like splicing regulator 1	in utero embryonic development	Biological process	-
RERGL	79785	RERG/RAS-like	membrane	Cellular component	-
FFAR4	338557	free fatty acid receptor 4	peptide binding	Molecular function	-
STRN	6801	striatin, calmodulin binding protein	negative regulation of cell proliferation	Biological process	18502210
PLRG1	5356	pleiotropic regulator 1	protein binding	Molecular function	20176811
DUOX1	53905	dual oxidase 1	response to oxidative stress	Biological process	-
TRAPPC2L	51693	trafficking protein particle complex 2-like	ER to Golgi vesicle-mediated transport	Biological process	-
Mar-02	54996	mitochondrial amidoxime reducing component 2	mitochondrial outer membrane	Cellular component	-
ALPK2	115701	alpha-kinase 2	nucleoplasm	Cellular component	-
SEC24D	9871	SEC24 family member D	COPII vesicle coat	Cellular component	10329445
SIRT7	51547	sirtuin 7	histone H4 deacetylation	Biological process	22722849
YWHAH	7533	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta	transcription initiation from RNA polymerase II promoter	Biological process	-
PRMT7	54496	protein arginine methyltransferase 7	nucleus	Cellular component	-
ATG7	10533	autophagy related 7	cytoplasm	Cellular component	20543840
EXOSC9	5393	exosome component 9	cytoplasm	Cellular component	17545563
KRT14	3861	keratin 14, type I	aging	Biological process	21916889
XRCC6	2547	X-ray repair complementing defective repair in Chinese hamster cells 6	double-strand break repair via nonhomologous end joining	Biological process	15824061
UTP14A	10813	UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)	nucleolus	Cellular component	-
ARID4A	5926	AT rich interactive domain 4A (RBP1-like)	chromatin organization	Biological process	-
TXNL4A	10907	thioredoxin-like 4A	protein binding	Molecular function	15840814
TGFBR2	7048	transforming growth factor, beta receptor II (70/80kDa)	lens fiber cell apoptotic process	Biological process	-
ANGPT2	285	angiopoietin 2	leukocyte migration	Biological process	-
UBC	7316	ubiquitin C	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition	Biological process	-
RNF2	6045	ring finger protein 2	mitotic cell cycle	Biological process	-
EFTUD2	9343	elongation factor Tu GTP binding domain containing 2	GTP binding	Molecular function	-
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	liver development	Biological process	-
ARG1	383	arginase 1	arginase activity	Molecular function	-
OMD	4958	osteomodulin	keratan sulfate metabolic process	Biological process	-
SRRM4	84530	serine/arginine repetitive matrix 4	nucleus	Cellular component	-
TFAP2B	7021	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	protein heterodimerization activity	Molecular function	11505339
AQP4	361	aquaporin 4	water transmembrane transporter activity	Molecular function	7559426
EHD3	30845	EH-domain containing 3	protein homooligomerization	Biological process	17233914
MAPK1	5594	mitogen-activated protein kinase 1	regulation of cytoskeleton organization	Biological process	19565474
PPA2	27068	pyrophosphatase (inorganic) 2	gene expression	Biological process	-
SERPINF1	5176	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1	cellular response to cobalt ion	Biological process	-
OR6N1	128372	olfactory receptor, family 6, subfamily N, member 1	G-protein coupled receptor activity	Molecular function	-
INTS7	25896	integrator complex subunit 7	integrator complex	Cellular component	16239144
OXTR	5021	oxytocin receptor	integral component of plasma membrane	Cellular component	10858434
RHCG	51458	Rh family, C glycoprotein	extracellular exosome	Cellular component	19056867
EREG	2069	epiregulin	female meiotic division	Biological process	-
GAPT	202309	GRB2-binding adaptor protein, transmembrane	immunoglobulin production involved in immunoglobulin mediated immune response	Biological process	-
NUAK2	81788	NUAK family, SNF1-like kinase, 2	AMP-activated protein kinase complex	Cellular component	-
KCNG1	3755	potassium channel, voltage gated modifier subfamily G, member 1	regulation of ion transmembrane transport	Biological process	-
CCL8	6355	chemokine (C-C motif) ligand 8	cell	Cellular component	10734056
CAMLG	819	calcium modulating ligand	defense response	Biological process	7522304
MARK1	4139	MAP/microtubule affinity-regulating kinase 1	cytoskeleton organization	Biological process	-
PROX1	5629	prospero homeobox 1	lens development in camera-type eye	Biological process	8812486
PPP3R1	5534	protein phosphatase 3, regulatory subunit B, alpha	protein binding	Molecular function	16648474
RAP1B	5908	RAP1B, member of RAS oncogene family	extracellular exosome	Cellular component	19199708
FBXO45	200933	F-box protein 45	corticospinal tract morphogenesis	Biological process	-
RPS11	6205	ribosomal protein S11	nucleolus	Cellular component	16791210
TRIM16	10626	tripartite motif containing 16	positive regulation of interleukin-1 beta secretion	Biological process	16575408
PHF21A	51317	PHD finger protein 21A	zinc ion binding	Molecular function	-
CRHBP	1393	corticotropin releasing hormone binding protein	learning or memory	Biological process	7477348
KIAA0101	9768	KIAA0101	DNA replication	Biological process	23000965
INPP5K	51763	inositol polyphosphate-5-phosphatase K	perinuclear region of cytoplasm	Cellular component	18774950
VHL	7428	von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase	enzyme binding	Molecular function	11641274
APELA	100506013	apelin receptor early endogenous ligand	mesendoderm migration	Biological process	-
ATP6V0B	533	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b	transferrin transport	Biological process	-
DERL1	79139	derlin 1	protease binding	Molecular function	25239945
PRKACA	5566	protein kinase, cAMP-dependent, catalytic, alpha	peptidyl-serine phosphorylation	Biological process	10805756
PITX2	5308	paired-like homeodomain 2	cardiac neural crest cell migration involved in outflow tract morphogenesis	Biological process	-
SECISBP2	79048	SECIS binding protein 2	nucleoplasm	Cellular component	-
C5orf30	90355	chromosome 5 open reading frame 30	protein binding	Molecular function	22085962
BNC1	646	basonuclin 1	epidermis development	Biological process	1332044
CYR61	3491	cysteine-rich, angiogenic inducer, 61	positive regulation of osteoblast differentiation	Biological process	20675382
DAP3	7818	death associated protein 3	mitochondrial translational initiation	Biological process	-
CAV3	859	caveolin 3	regulation of p38MAPK cascade	Biological process	-
STAB1	23166	stabilin 1	hyaluronic acid binding	Molecular function	-
TFAP4	7023	transcription factor AP-4 (activating enhancer binding protein 4)	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
AWAT1	158833	acyl-CoA wax alcohol acyltransferase 1	lipid metabolic process	Biological process	-
RAPGEF4	11069	Rap guanine nucleotide exchange factor (GEF) 4	Ras GTPase binding	Molecular function	-
HOXA1	3198	homeobox A1	cochlea development	Biological process	16155570
MAP2K3	5606	mitogen-activated protein kinase kinase 3	signal transduction by protein phosphorylation	Biological process	-
RNASE6	6039	ribonuclease, RNase A family, k6	defense response	Biological process	8836175
PIK3R6	146850	phosphoinositide-3-kinase, regulatory subunit 6	membrane	Cellular component	-
MTF2	22823	metal response element binding transcription factor 2	chromatin modification	Biological process	-
ABCC9	10060	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	voltage-gated potassium channel complex	Cellular component	20610380
TTLL5	23093	tubulin tyrosine ligase-like family member 5	cilium	Cellular component	-
HSPA1A	3303	heat shock 70kDa protein 1A	virus receptor activity	Molecular function	-
OR4F3	26683	olfactory receptor, family 4, subfamily F, member 3	olfactory receptor activity	Molecular function	-
CARD9	64170	caspase recruitment domain family, member 9	response to drug	Biological process	-
BCL3	602	B-cell CLL/lymphoma 3	regulation of NF-kappaB import into nucleus	Biological process	8196632
PCSK9	255738	proprotein convertase subtilisin/kexin type 9	positive regulation of low-density lipoprotein particle receptor catabolic process	Biological process	22848640
GOLGA4	2803	golgin A4	nucleoplasm	Cellular component	-
HSPG2	3339	heparan sulfate proteoglycan 2	Golgi lumen	Cellular component	-
MTSS1L	92154	metastasis suppressor 1-like	actin binding	Molecular function	-
DUSP8	1850	dual specificity phosphatase 8	nucleus	Cellular component	-
CYP1B1	1545	cytochrome P450, family 1, subfamily B, polypeptide 1	endoplasmic reticulum membrane	Cellular component	-
C4B	721	complement component 4B (Chido blood group)	regulation of complement activation	Biological process	-
ANGPT2	285	angiopoietin 2	extracellular space	Cellular component	9660821
PLCG2	5336	phospholipase C, gamma 2 (phosphatidylinositol-specific)	phospholipase C activity	Molecular function	-
HCRTR1	3061	hypocretin (orexin) receptor 1	peptide binding	Molecular function	-
RPA3	6119	replication protein A3, 14kDa	DNA replication factor A complex	Cellular component	11927569
BCL2	596	B-cell CLL/lymphoma 2	endoplasmic reticulum calcium ion homeostasis	Biological process	18309324
SCG2	7857	secretogranin II	secretory granule	Cellular component	-
SHROOM3	57619	shroom family member 3	regulation of cell shape	Biological process	-
SPTBN2	6712	spectrin, beta, non-erythrocytic 2	cytoplasm	Cellular component	-
EXT2	2132	exostosin glycosyltransferase 2	membrane	Cellular component	19946888
MINPP1	9562	multiple inositol-polyphosphate phosphatase 1	endoplasmic reticulum lumen	Cellular component	-
TOR1A	1861	torsin family 1, member A (torsin A)	intracellular membrane-bounded organelle	Cellular component	-
DYNC2LI1	51626	dynein, cytoplasmic 2, light intermediate chain 1	antigen processing and presentation of exogenous peptide antigen via MHC class II	Biological process	-
SCARB1	949	scavenger receptor class B, member 1	microvillus membrane	Cellular component	-
CBX5	23468	chromobox homolog 5	protein binding, bridging	Molecular function	-
UTY	7404	ubiquitously transcribed tetratricopeptide repeat containing, Y-linked	nucleus	Cellular component	-
TAOK3	51347	TAO kinase 3	negative regulation of protein kinase activity	Biological process	10559204
ZNF812	729648	zinc finger protein 812	metal ion binding	Molecular function	-
TLR2	7097	toll-like receptor 2	negative regulation of interleukin-12 production	Biological process	-
MAN2A1	4124	mannosidase, alpha, class 2A, member 1	cellular protein metabolic process	Biological process	-
GNAS	2778	GNAS complex locus	water transport	Biological process	-
TINAG	27283	tubulointerstitial nephritis antigen	receptor-mediated endocytosis	Biological process	-
TUFM	7284	Tu translation elongation factor, mitochondrial	poly(A) RNA binding	Molecular function	22658674
PCDHA10	56139	protocadherin alpha 10	integral component of plasma membrane	Cellular component	10380929
USP17L10	100287144	ubiquitin specific peptidase 17-like family member 10	nucleus	Cellular component	-
ABCC9	10060	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	ATP binding	Molecular function	-
CD164	8763	CD164 molecule, sialomucin	integral component of plasma membrane	Cellular component	11027692
ENG	2022	endoglin	extracellular matrix disassembly	Biological process	18223685
EDN3	1908	endothelin 3	cell surface receptor signaling pathway	Biological process	1713452
MARVELD1	83742	MARVEL domain containing 1	cytoskeleton	Cellular component	-
TENM3	55714	teneurin transmembrane protein 3	protein homodimerization activity	Molecular function	-
ABI2	10152	abl-interactor 2	cytoplasm	Cellular component	8649853
HOXA2	3199	homeobox A2	middle ear morphogenesis	Biological process	-
ACP1	52	acid phosphatase 1, soluble	protein binding	Molecular function	15846844
GALNT1	2589	polypeptide N-acetylgalactosaminyltransferase 1	polypeptide N-acetylgalactosaminyltransferase activity	Molecular function	9295285
FOXS1	2307	forkhead box S1	positive regulation of multicellular organism growth	Biological process	-
AKR1C1	1645	aldo-keto reductase family 1, member C1	xenobiotic metabolic process	Biological process	8486699
ACAT1	38	acetyl-CoA acetyltransferase 1	branched-chain amino acid catabolic process	Biological process	-
SNRPF	6636	small nuclear ribonucleoprotein polypeptide F	nucleoplasm	Cellular component	-
POU1F1	5449	POU class 1 homeobox 1	positive regulation of transcription, DNA-templated	Biological process	9482665
ARHGAP24	83478	Rho GTPase activating protein 24	regulation of small GTPase mediated signal transduction	Biological process	-
MMP3	4314	matrix metallopeptidase 3	collagen catabolic process	Biological process	-
UGT1A4	54657	UDP glucuronosyltransferase 1 family, polypeptide A4	endoplasmic reticulum membrane	Cellular component	-
HSPD1	3329	heat shock 60kDa protein 1 (chaperonin)	positive regulation of macrophage activation	Biological process	17164250
GSTO2	119391	glutathione S-transferase omega 2	glutathione transferase activity	Molecular function	-
RBBP6	5930	retinoblastoma binding protein 6	somite development	Biological process	-
SNAP29	9342	synaptosomal-associated protein, 29kDa	protein transport	Biological process	-
GEMIN6	79833	gem (nuclear organelle) associated protein 6	cytoplasm	Cellular component	11748230
IGF2BP1	10642	insulin-like growth factor 2 mRNA binding protein 1	dendritic spine	Cellular component	-
BAIAP2	10458	BAI1-associated protein 2	identical protein binding	Molecular function	11696321
PDK3	5165	pyruvate dehydrogenase kinase, isozyme 3	mitochondrion	Cellular component	7499431
PHF5A	84844	PHD finger protein 5A	U12-type spliceosomal complex	Cellular component	15146077
HDGFRP2	84717	hepatoma-derived growth factor-related protein 2	DNA binding	Molecular function	-
RNF2	6045	ring finger protein 2	protein binding	Molecular function	10369680
KIF16B	55614	kinesin family member 16B	early endosome to late endosome transport	Biological process	15882625
ERBB2	2064	erb-b2 receptor tyrosine kinase 2	positive regulation of protein phosphorylation	Biological process	-
BCS1L	617	BC1 (ubiquinol-cytochrome c reductase) synthesis-like	ATP binding	Molecular function	-
PGR	5241	progesterone receptor	receptor binding	Molecular function	12771131
RXFP4	339403	relaxin/insulin-like family peptide receptor 4	integral component of membrane	Cellular component	-
DDB1	1642	damage-specific DNA binding protein 1, 127kDa	negative regulation of apoptotic process	Biological process	-
SKA2	348235	spindle and kinetochore associated complex subunit 2	chromosome segregation	Biological process	19289083
ZNF621	285268	zinc finger protein 621	metal ion binding	Molecular function	-
PDPK1	5170	3-phosphoinositide dependent protein kinase 1	actin cytoskeleton organization	Biological process	10792047
GTF2H3	2967	general transcription factor IIH, polypeptide 3, 34kDa	transcription from RNA polymerase II promoter	Biological process	-
TMPRSS9	360200	transmembrane protease, serine 9	integral component of plasma membrane	Cellular component	-
RPS6KB1	6198	ribosomal protein S6 kinase, 70kDa, polypeptide 1	perinuclear region of cytoplasm	Cellular component	-
ALDH1L1	10840	aldehyde dehydrogenase 1 family, member L1	hydroxymethyl-, formyl- and related transferase activity	Molecular function	-
RNF170	81790	ring finger protein 170	ligase activity	Molecular function	-
OGG1	4968	8-oxoguanine DNA glycosylase	microtubule binding	Molecular function	-
VIL1	7429	villin 1	cellular response to hepatocyte growth factor stimulus	Biological process	-
OMD	4958	osteomodulin	regulation of bone mineralization	Biological process	-
AHCTF1	25909	AT hook containing transcription factor 1	mRNA transport	Biological process	-
AK7	122481	adenylate kinase 7	ATP binding	Molecular function	-
DNASE2B	58511	deoxyribonuclease II beta	apoptotic DNA fragmentation	Biological process	-
UHRF2	115426	ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase	ligase activity	Molecular function	-
DYSF	8291	dysferlin	vesicle fusion	Biological process	-
DNAJC5	80331	DnaJ (Hsp40) homolog, subfamily C, member 5	membrane	Cellular component	19946888
PMEPA1	56937	prostate transmembrane protein, androgen induced 1	R-SMAD binding	Molecular function	20129061
SLC6A3	6531	solute carrier family 6 (neurotransmitter transporter), member 3	prepulse inhibition	Biological process	-
SEH1L	81929	SEH1-like (S. cerevisiae)	cytokine-mediated signaling pathway	Biological process	-
EXT2	2132	exostosin glycosyltransferase 2	protein heterodimerization activity	Molecular function	12907669
EIF3A	8661	eukaryotic translation initiation factor 3, subunit A	cellular protein metabolic process	Biological process	-
GNAI2	2771	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	regulation of calcium ion transport	Biological process	-
GDNF	2668	glial cell derived neurotrophic factor	regulation of stem cell differentiation	Biological process	23626767
TNP2	7142	transition protein 2 (during histone to protamine replacement)	spermatogenesis	Biological process	-
FGD1	2245	FYVE, RhoGEF and PH domain containing 1	cytoskeleton	Cellular component	-
RPL28	6158	ribosomal protein L28	SRP-dependent cotranslational protein targeting to membrane	Biological process	-
JAGN1	84522	jagunal homolog 1 (Drosophila)	protein transport	Biological process	-
ZDHHC14	79683	zinc finger, DHHC-type containing 14	zinc ion binding	Molecular function	-
ZNF25	219749	zinc finger protein 25	regulation of transcription, DNA-templated	Biological process	-
SLC14A1	6563	solute carrier family 14 (urea transporter), member 1 (Kidd blood group)	water transport	Biological process	-
CDK18	5129	cyclin-dependent kinase 18	cellular_component	Cellular component	-
TTC23L	153657	tetratricopeptide repeat domain 23-like	protein binding	Molecular function	22458338
FAM129B	64855	family with sequence similarity 129, member B	extracellular exosome	Cellular component	19056867
ACSL4	2182	acyl-CoA synthetase long-chain family member 4	cellular lipid metabolic process	Biological process	-
CARTPT	9607	CART prepropeptide	positive regulation of blood pressure	Biological process	11711504
PPIA	5478	peptidylprolyl isomerase A (cyclophilin A)	uncoating of virus	Biological process	-
YME1L1	10730	YME1-like 1 ATPase	misfolded or incompletely synthesized protein catabolic process	Biological process	22262461
ZBTB47	92999	zinc finger and BTB domain containing 47	transcription, DNA-templated	Biological process	-
NAA15	80155	N(alpha)-acetyltransferase 15, NatA auxiliary subunit	cell differentiation	Biological process	-
HSPB9	94086	heat shock protein, alpha-crystallin-related, B9	protein binding	Molecular function	15503857
NR1H2	7376	nuclear receptor subfamily 1, group H, member 2	positive regulation of cholesterol transport	Biological process	16141411
CDYL	9425	chromodomain protein, Y-like	spermatogenesis	Biological process	10192397
RHOXF1	158800	Rhox homeobox family, member 1	gamete generation	Biological process	11980563
BIRC5	332	baculoviral IAP repeat containing 5	establishment of chromosome localization	Biological process	12805209
ROPN1B	152015	rhophilin associated tail protein 1B	protein heterodimerization activity	Molecular function	11278869
HLA-A	3105	major histocompatibility complex, class I, A	endoplasmic reticulum exit site	Cellular component	20946353
CYBA	1535	cytochrome b-245, alpha polypeptide	cytochrome complex assembly	Biological process	7938008
MAP3K7	6885	mitogen-activated protein kinase kinase kinase 7	JNK cascade	Biological process	-
POLR2G	5436	polymerase (RNA) II (DNA directed) polypeptide G	cytoplasmic mRNA processing body	Cellular component	-
CENPF	1063	centromere protein F, 350/400kDa	protein binding	Molecular function	17043677
CDH1	999	cadherin 1, type 1, E-cadherin (epithelial)	cellular response to indole-3-methanol	Biological process	10868478
ADD1	118	adducin 1 (alpha)	actin filament bundle assembly	Biological process	3693401
SLC51B	123264	solute carrier family 51, beta subunit	plasma membrane	Cellular component	12719432
EHHADH	1962	enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase	internal protein amino acid acetylation	Biological process	20167786
DFNA5	1687	deafness, autosomal dominant 5	sensory perception of sound	Biological process	9771715
CGRRF1	10668	cell growth regulator with ring finger domain 1	negative regulation of cell proliferation	Biological process	8968090
UGT2B4	7363	UDP glucuronosyltransferase 2 family, polypeptide B4	cellular glucuronidation	Biological process	20056724
KRT6A	3853	keratin 6A, type II	activation of mitophagy in response to mitochondrial depolarization	Biological process	22020285
TSSK3	81629	testis-specific serine kinase 3	ATP binding	Molecular function	-
PDGFB	5155	platelet-derived growth factor beta polypeptide	metanephric glomerular endothelium development	Biological process	-
GCLC	2729	glutamate-cysteine ligase, catalytic subunit	response to heat	Biological process	8104187
SEC14L6	730005	SEC14-like 6 (S. cerevisiae)	intracellular	Cellular component	-
TP53	7157	tumor protein p53	endoplasmic reticulum	Cellular component	-
JDP2	122953	Jun dimerization protein 2	protein heterodimerization activity	Molecular function	-
DAGLB	221955	diacylglycerol lipase, beta	lipid catabolic process	Biological process	-
SGCG	6445	sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)	muscle organ development	Biological process	8641426
CACNA2D4	93589	calcium channel, voltage-dependent, alpha 2/delta subunit 4	regulation of ion transmembrane transport	Biological process	-
BEX1	55859	brain expressed, X-linked 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	16314316
CHRNA7	1139	cholinergic receptor, nicotinic, alpha 7 (neuronal)	response to nicotine	Biological process	12189247
APC	324	adenomatous polyposis coli	cytoplasm	Cellular component	11035805
MBNL1	4154	muscleblind-like splicing regulator 1	double-stranded RNA binding	Molecular function	10970838
TBX2	6909	T-box 2	negative regulation of heart looping	Biological process	-
RXRA	6256	retinoid X receptor, alpha	maternal placenta development	Biological process	-
MTSS1	9788	metastasis suppressor 1	negative regulation of epithelial cell proliferation	Biological process	-
NKX3-1	4824	NK3 homeobox 1	nucleus	Cellular component	11137288
RPS3	6188	ribosomal protein S3	membrane	Cellular component	19946888
PRAMEF17	391004	PRAME family member 17	positive regulation of cell proliferation	Biological process	-
PCSK1N	27344	proprotein convertase subtilisin/kexin type 1 inhibitor	response to cold	Biological process	-
UPK3A	7380	uroplakin 3A	kidney development	Biological process	-
FOXO3	2309	forkhead box O3	DNA damage response, signal transduction by p53 class mediator	Biological process	-
PER3	8863	period circadian clock 3	protein binding	Molecular function	21070773
POLR2C	5432	polymerase (RNA) II (DNA directed) polypeptide C, 33kDa	mRNA splicing, via spliceosome	Biological process	-
KIFC1	3833	kinesin family member C1	microtubule	Cellular component	-
ATF4	468	activating transcription factor 4	regulation of transcription, DNA-templated	Biological process	-
TYMS	7298	thymidylate synthetase	G1/S transition of mitotic cell cycle	Biological process	-
HELLS	3070	helicase, lymphoid-specific	transcription, DNA-templated	Biological process	-
FUBP1	8880	far upstream element (FUSE) binding protein 1	positive regulation of gene expression	Biological process	19087307
DUSP16	80824	dual specificity phosphatase 16	MAPK export from nucleus	Biological process	11489891
ERCC2	2068	excision repair cross-complementation group 2	nucleoplasm	Cellular component	-
ZXDA	7789	zinc finger, X-linked, duplicated A	positive regulation of transcription, DNA-templated	Biological process	17493635
FOXO3	2309	forkhead box O3	cell differentiation	Biological process	-
VTN	7448	vitronectin	positive regulation of cell-substrate adhesion	Biological process	-
TENM1	10178	teneurin transmembrane protein 1	regulation of transcription from RNA polymerase III promoter	Biological process	-
CYP8B1	1582	cytochrome P450, family 8, subfamily B, polypeptide 1	xenobiotic metabolic process	Biological process	-
ENOX2	10495	ecto-NOX disulfide-thiol exchanger 2	nucleic acid binding	Molecular function	-
HNRNPA0	10949	heterogeneous nuclear ribonucleoprotein A0	mRNA processing	Biological process	7585247
CCNB1	891	cyclin B1	histone kinase activity	Molecular function	-
DICER1	23405	dicer 1, ribonuclease type III	pre-miRNA binding	Molecular function	18178619
NR0B2	8431	nuclear receptor subfamily 0, group B, member 2	sequence-specific DNA binding transcription factor activity	Molecular function	-
FANCG	2189	Fanconi anemia, complementation group G	response to radiation	Biological process	-
DIXDC1	85458	DIX domain containing 1	positive regulation of canonical Wnt signaling pathway	Biological process	21189423
MRPL45	84311	mitochondrial ribosomal protein L45	mitochondrion	Cellular component	-
MICALL1	85377	MICAL-like 1	zinc ion binding	Molecular function	-
NIN	51199	ninein (GSK3B interacting protein)	centrosome localization	Biological process	16154161
FAM189A2	9413	family with sequence similarity 189, member A2	biological_process	Biological process	-
SOX2	6657	SRY (sex determining region Y)-box 2	somatic stem cell maintenance	Biological process	-
LRMP	4033	lymphoid-restricted membrane protein	integral component of endoplasmic reticulum membrane	Cellular component	-
DAZL	1618	deleted in azoospermia-like	germ cell development	Biological process	9288969
STAP1	26228	signal transducing adaptor family member 1	cytoplasm	Cellular component	17936702
AGTPBP1	23287	ATP/GTP binding protein 1	zinc ion binding	Molecular function	-
CHP1	11261	calcineurin-like EF-hand protein 1	cytosol	Cellular component	-
C1QTNF1	114897	C1q and tumor necrosis factor related protein 1	protein homooligomerization	Biological process	-
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	cell-cell junction	Cellular component	19151727
MAN2A1	4124	mannosidase, alpha, class 2A, member 1	mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity	Molecular function	-
ULBP3	79465	UL16 binding protein 3	peptide antigen binding	Molecular function	-
PROM2	150696	prominin 2	cholesterol binding	Molecular function	12514187
SF3B1	23451	splicing factor 3b, subunit 1, 155kDa	spliceosomal complex	Cellular component	9585501
CACNA2D2	9254	calcium channel, voltage-dependent, alpha 2/delta subunit 2	neuromuscular junction development	Biological process	-
ADCK4	79934	aarF domain containing kinase 4	plasma membrane	Cellular component	-
AHNAK	79026	AHNAK nucleoprotein	plasma membrane	Cellular component	21940993
FAM90A15P	389630	putative protein FAM90A15	zinc ion binding	Molecular function	-
UBC	7316	ubiquitin C	negative regulation of epidermal growth factor receptor signaling pathway	Biological process	-
USP28	57646	ubiquitin specific peptidase 28	response to ionizing radiation	Biological process	16901786
GHR	2690	growth hormone receptor	protein kinase binding	Molecular function	-
MYH9	4627	myosin, heavy chain 9, non-muscle	myosin II complex	Cellular component	24072716
FADS2P1	643181	fatty acid desaturase 2 pseudogene 1	integral component of membrane	Cellular component	-
C2CD3	26005	C2 calcium-dependent domain containing 3	organelle organization	Biological process	-
SIX4	51804	SIX homeobox 4	transcription, DNA-templated	Biological process	-
HSPA1B	3304	heat shock 70kDa protein 1B	C3HC4-type RING finger domain binding	Molecular function	25281747
MST1R	4486	macrophage stimulating 1 receptor	positive regulation of protein kinase B signaling	Biological process	12676986
TFAP2B	7021	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	negative regulation of neuron apoptotic process	Biological process	-
SPTB	6710	spectrin, beta, erythrocytic	cytosol	Cellular component	-
DHFRL1	200895	dihydrofolate reductase-like 1	nucleotide biosynthetic process	Biological process	-
NKX3-1	4824	NK3 homeobox 1	negative regulation of cell proliferation	Biological process	17486276
PTPRC	5788	protein tyrosine phosphatase, receptor type, C	cell surface	Cellular component	24337748
HSD17B4	3295	hydroxysteroid (17-beta) dehydrogenase 4	long-chain-enoyl-CoA hydratase activity	Molecular function	-
PHC1	1911	polyhomeotic homolog 1 (Drosophila)	cellular response to retinoic acid	Biological process	-
NUDT21	11051	nudix (nucleoside diphosphate linked moiety X)-type motif 21	nucleus	Cellular component	20695905
TMEM189	387521	transmembrane protein 189	protein ubiquitination	Biological process	-
OPTC	26254	opticin	extracellular matrix structural constituent	Molecular function	10636917
NOTCH2	4853	notch 2	cell surface	Cellular component	9244302
FDFT1	2222	farnesyl-diphosphate farnesyltransferase 1	steroid biosynthetic process	Biological process	8474436
L1RE1	4029	LINE1 retrotransposable element 1	ribonucleoprotein complex	Cellular component	16183655
C7orf60	154743	chromosome 7 open reading frame 60	rRNA methylation	Biological process	-
F2RL1	2150	coagulation factor II (thrombin) receptor-like 1	positive regulation of ERK1 and ERK2 cascade	Biological process	-
PRPF19	27339	pre-mRNA processing factor 19	site of double-strand break	Cellular component	18263876
VSX2	338917	visual system homeobox 2	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
CEL	1056	carboxyl ester lipase	intestinal cholesterol absorption	Biological process	12031288
NCF4	4689	neutrophil cytosolic factor 4, 40kDa	immune response	Biological process	8280052
RPL11	6135	ribosomal protein L11	viral life cycle	Biological process	-
CCKAR	886	cholecystokinin A receptor	forebrain development	Biological process	-
OR1J1	347168	olfactory receptor, family 1, subfamily J, member 1	integral component of membrane	Cellular component	-
RYR2	6262	ryanodine receptor 2 (cardiac)	calmodulin binding	Molecular function	-
CRIP1	1396	cysteine-rich protein 1 (intestinal)	cell proliferation	Biological process	9126610
NOD1	10392	nucleotide-binding oligomerization domain containing 1	protein homodimerization activity	Molecular function	18186648
SDHB	6390	succinate dehydrogenase complex, subunit B, iron sulfur (Ip)	4 iron, 4 sulfur cluster binding	Molecular function	-
HS3ST3A1	9955	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	sulfotransferase activity	Molecular function	9988767
NFKBIB	4793	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	signal transducer activity	Molecular function	7776974
FGF12	2257	fibroblast growth factor 12	ion channel binding	Molecular function	12401812
MED8	112950	mediator complex subunit 8	gene expression	Biological process	-
GADD45B	4616	growth arrest and DNA-damage-inducible, beta	regulation of cell cycle	Biological process	-
MRPL44	65080	mitochondrial ribosomal protein L44	mitochondrial inner membrane	Cellular component	-
RAB4A	5867	RAB4A, member RAS oncogene family	insulin-responsive compartment	Cellular component	-
PAX8	7849	paired box 8	pronephros development	Biological process	-
TNFSF13	8741	tumor necrosis factor (ligand) superfamily, member 13	positive regulation of isotype switching to IgA isotypes	Biological process	14988498
SRSF10	10772	serine/arginine-rich splicing factor 10	unfolded protein binding	Molecular function	11684676
ODF2	4957	outer dense fiber of sperm tails 2	organelle organization	Biological process	-
BBS9	27241	Bardet-Biedl syndrome 9	ciliary transition zone	Cellular component	23943788
PPARA	5465	peroxisome proliferator-activated receptor alpha	sequence-specific DNA binding transcription factor activity	Molecular function	-
DHX15	1665	DEAH (Asp-Glu-Ala-His) box helicase 15	U2-type post-mRNA release spliceosomal complex	Cellular component	19103666
PON2	5445	paraoxonase 2	nucleus	Cellular component	-
TNRC6B	23112	trinucleotide repeat containing 6B	Fc-epsilon receptor signaling pathway	Biological process	-
DCTN5	84516	dynactin 5 (p25)	protein binding	Molecular function	25416956
ITGB1	3688	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	regulation of G-protein coupled receptor protein signaling pathway	Biological process	-
DTNA	1837	dystrobrevin, alpha	PDZ domain binding	Molecular function	-
NDUFA10	4705	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa	nucleotide biosynthetic process	Biological process	-
CPT1C	126129	carnitine palmitoyltransferase 1C	synapse	Cellular component	-
PRICKLE1	144165	prickle homolog 1 (Drosophila)	zinc ion binding	Molecular function	-
PLEC	5339	plectin	ankyrin binding	Molecular function	21223964
EDDM3A	10876	epididymal protein 3A	sperm displacement	Biological process	7514008
ZNF584	201514	zinc finger protein 584	regulation of transcription, DNA-templated	Biological process	-
SLC9A2	6549	solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2	regulation of pH	Biological process	-
LRP4	4038	low density lipoprotein receptor-related protein 4	skeletal muscle acetylcholine-gated channel clustering	Biological process	-
NOL3	8996	nucleolar protein 3 (apoptosis repressor with CARD domain)	caspase binding	Molecular function	15509781
TBP	6908	TATA box binding protein	chromatin silencing at rDNA	Biological process	-
RAB7A	7879	RAB7A, member RAS oncogene family	phagosome-lysosome fusion	Biological process	21255211
CDK5	1020	cyclin-dependent kinase 5	axon extension	Biological process	21473899
MIA3	375056	melanoma inhibitory activity family, member 3	negative regulation of cell migration	Biological process	17044017
PLS3	5358	plastin 3	cytoplasm	Cellular component	-
SLC15A3	51296	solute carrier family 15 (oligopeptide transporter), member 3	peptide transport	Biological process	-
REST	5978	RE1-silencing transcription factor	cytosol	Cellular component	-
CD248	57124	CD248 molecule, endosialin	proteinaceous extracellular matrix	Cellular component	10947988
SLC11A1	6556	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1	iron ion homeostasis	Biological process	-
KIF26B	55083	kinesin family member 26B	cytoplasm	Cellular component	-
ATP8A2	51761	ATPase, aminophospholipid transporter, class I, type 8A, member 2	axonogenesis	Biological process	-
MAP2K1	5604	mitogen-activated protein kinase kinase 1	labyrinthine layer development	Biological process	-
UBB	7314	ubiquitin B	translesion synthesis	Biological process	-
LTA4H	4048	leukotriene A4 hydrolase	metallopeptidase activity	Molecular function	-
APOH	350	apolipoprotein H (beta-2-glycoprotein I)	cell surface	Cellular component	16480936
ADGRL3	23284	adhesion G protein-coupled receptor L3	integral component of membrane	Cellular component	10994649
ABCB1	5243	ATP-binding cassette, sub-family B (MDR/TAP), member 1	transporter activity	Molecular function	3022150
AREL1	9870	apoptosis resistant E3 ubiquitin protein ligase 1	ligase activity	Molecular function	-
TANK	10010	TRAF family member-associated NFKB activator	cytoplasm	Cellular component	-
GNG2	54331	guanine nucleotide binding protein (G protein), gamma 2	cellular response to glucagon stimulus	Biological process	-
HEYL	26508	hes-related family bHLH transcription factor with YRPW motif-like	AF-1 domain binding	Molecular function	21454491
PLK4	10733	polo-like kinase 4	deuterosome	Cellular component	-
CAPRIN1	4076	cell cycle associated protein 1	positive regulation of dendritic spine morphogenesis	Biological process	-
CLU	1191	clusterin	protein binding	Molecular function	16113678
BPIFB1	92747	BPI fold containing family B, member 1	extracellular region	Cellular component	20237794
NLRC5	84166	NLR family, CARD domain containing 5	positive regulation of MHC class I biosynthetic process	Biological process	20639463
SKI	6497	SKI proto-oncogene	transcription corepressor activity	Molecular function	12435627
CDC45	8318	cell division cycle 45	mitotic DNA replication preinitiation complex assembly	Biological process	-
NDUFS4	4724	NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)	regulation of protein phosphorylation	Biological process	11165261
CDC42EP3	10602	CDC42 effector protein (Rho GTPase binding) 3	GTP-Rho binding	Molecular function	-
FETUB	26998	fetuin B	extracellular exosome	Cellular component	23533145
PDCD4	27250	programmed cell death 4 (neoplastic transformation inhibitor)	RNA binding	Molecular function	-
KCNB2	9312	potassium channel, voltage gated Shab related subfamily B, member 2	delayed rectifier potassium channel activity	Molecular function	-
SLC38A4	55089	solute carrier family 38, member 4	integral component of plasma membrane	Cellular component	-
NR2E3	10002	nuclear receptor subfamily 2, group E, member 3	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
OPA3	80207	optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)	mitochondrion morphogenesis	Biological process	-
TAF6L	10629	TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa	histone H3 acetylation	Biological process	11564863
PLD2	5338	phospholipase D2	phosphatidylglycerol biosynthetic process	Biological process	-
MINK1	50488	misshapen-like kinase 1	extracellular exosome	Cellular component	19056867
PURA	5813	purine-rich element binding protein A	nuclear chromosome, telomeric region	Cellular component	15777841
SYCP2	10388	synaptonemal complex protein 2	DNA binding	Molecular function	10341103
KCNJ4	3761	potassium channel, inwardly rectifying subfamily J, member 4	protein binding	Molecular function	16855024
PLAU	5328	plasminogen activator, urokinase	extracellular region	Cellular component	-
ERCC6	2074	excision repair cross-complementation group 6	multicellular organism growth	Biological process	-
NEURL1	9148	neuralized E3 ubiquitin protein ligase 1	positive regulation of synapse maturation	Biological process	-
CCNK	8812	cyclin K	protein phosphorylation	Biological process	9632813
FXR2	9513	fragile X mental retardation, autosomal homolog 2	cytoplasm	Cellular component	-
TMBIM4	51643	transmembrane BAX inhibitor motif containing 4	protein binding	Molecular function	19553469
TPI1	7167	triosephosphate isomerase 1	carbohydrate metabolic process	Biological process	-
ATP5G2	517	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)	integral component of membrane	Cellular component	-
ICAM1	3383	intercellular adhesion molecule 1	plasma membrane	Cellular component	-
MGAT4C	25834	MGAT4 family, member C	integral component of membrane	Cellular component	-
PLAUR	5329	plasminogen activator, urokinase receptor	integral component of membrane	Cellular component	1689240
NRP1	8829	neuropilin 1	angiogenesis	Biological process	24401374
MMP9	4318	matrix metallopeptidase 9	proteinaceous extracellular matrix	Cellular component	-
INPP4B	8821	inositol polyphosphate-4-phosphatase, type II, 105kDa	cellular calcium ion homeostasis	Biological process	-
IQGAP1	8826	IQ motif containing GTPase activating protein 1	positive regulation of GTPase activity	Biological process	8051149
HIST1H2AC	8334	histone cluster 1, H2ac	DNA binding	Molecular function	-
PDGFRA	5156	platelet-derived growth factor receptor, alpha polypeptide	positive regulation of phosphatidylinositol 3-kinase signaling	Biological process	10734113
CYFIP1	23191	cytoplasmic FMR1 interacting protein 1	ruffle	Cellular component	-
CD74	972	CD74 molecule, major histocompatibility complex, class II invariant chain	positive regulation of type 2 immune response	Biological process	-
HS3ST5	222537	heparan sulfate (glucosamine) 3-O-sulfotransferase 5	glycosaminoglycan biosynthetic process	Biological process	-
RTN4R	65078	reticulon 4 receptor	protein binding	Molecular function	20463223
HERC2	8924	HECT and RLD domain containing E3 ubiquitin protein ligase 2	spermatogenesis	Biological process	-
SRPX2	27286	sushi-repeat containing protein, X-linked 2	receptor binding	Molecular function	18718938
EPHA5	2044	EPH receptor A5	regulation of GTPase activity	Biological process	-
IGF1R	3480	insulin-like growth factor 1 receptor	positive regulation of cytokinesis	Biological process	-
CAPN11	11131	calpain 11	cytoplasm	Cellular component	-
FARSA	2193	phenylalanyl-tRNA synthetase, alpha subunit	poly(A) RNA binding	Molecular function	22681889
PIK3CD	5293	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	mast cell granule	Cellular component	20940048
GRIK2	2898	glutamate receptor, ionotropic, kainate 2	postsynaptic density	Cellular component	-
GSTO2	119391	glutathione S-transferase omega 2	extracellular exosome	Cellular component	19056867
PCNP	57092	PEST proteolytic signal containing nuclear protein	protein binding	Molecular function	12176013
FSCN2	25794	fascin actin-bundling protein 2, retinal	cytoplasm	Cellular component	-
CD1B	910	CD1b molecule	immune response	Biological process	-
ART4	420	ADP-ribosyltransferase 4 (Dombrock blood group)	anchored component of membrane	Cellular component	-
GNA13	10672	guanine nucleotide binding protein (G protein), alpha 13	in utero embryonic development	Biological process	-
GABRD	2563	gamma-aminobutyric acid (GABA) A receptor, delta	chloride channel activity	Molecular function	-
TMED7	51014	transmembrane emp24 protein transport domain containing 7	COPI vesicle coat	Cellular component	10359607
STX19	415117	syntaxin 19	integral component of membrane	Cellular component	-
RCAN2	10231	regulator of calcineurin 2	cytoplasm	Cellular component	-
EEF2	1938	eukaryotic translation elongation factor 2	polysome	Cellular component	-
RBMY1F	159163	RNA binding motif protein, Y-linked, family 1, member F	protein binding	Molecular function	25416956
TXN	7295	thioredoxin	cytosol	Cellular component	-
SLC2A4RG	56731	SLC2A4 regulator	nucleoplasm	Cellular component	-
STAG2	10735	stromal antigen 2	membrane	Cellular component	19946888
ID1	3397	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	Golgi apparatus	Cellular component	-
SYVN1	84447	synovial apoptosis inhibitor 1, synoviolin	ligase activity	Molecular function	-
PDGFRB	5159	platelet-derived growth factor receptor, beta polypeptide	platelet-derived growth factor beta-receptor activity	Molecular function	2554309
NSG1	27065	neuron specific gene family member 1	Golgi membrane	Cellular component	-
PACSIN2	11252	protein kinase C and casein kinase substrate in neurons 2	cytoplasmic vesicle membrane	Cellular component	-
ARHGAP12	94134	Rho GTPase activating protein 12	morphogenesis of an epithelial sheet	Biological process	23201090
FMR1NB	158521	fragile X mental retardation 1 neighbor	nucleolus	Cellular component	-
VPS37D	155382	vacuolar protein sorting 37 homolog D (S. cerevisiae)	viral life cycle	Biological process	-
VWA8	23078	von Willebrand factor A domain containing 8	metabolic process	Biological process	-
AKAP6	9472	A kinase (PRKA) anchor protein 6	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	Biological process	-
RALGAPA1	253959	Ral GTPase activating protein, alpha subunit 1 (catalytic)	activation of GTPase activity	Biological process	-
SMC1A	8243	structural maintenance of chromosomes 1A	DNA repair	Biological process	11877377
ERCC1	2067	excision repair cross-complementation group 1	response to nutrient	Biological process	-
TRIM26	7726	tripartite motif containing 26	interferon-gamma-mediated signaling pathway	Biological process	-
SPINK5	11005	serine peptidase inhibitor, Kazal type 5	negative regulation of endopeptidase activity	Biological process	-
APBA3	9546	amyloid beta (A4) precursor protein-binding, family A, member 3	in utero embryonic development	Biological process	-
VTA1	51534	vesicle (multivesicular body) trafficking 1	viral budding	Biological process	15644320
MSGN1	343930	mesogenin 1	nucleus	Cellular component	-
COL8A1	1295	collagen, type VIII, alpha 1	camera-type eye morphogenesis	Biological process	-
STAMBP	10617	STAM binding protein	ubiquitin-specific protease activity	Molecular function	18388320
CTSS	1520	cathepsin S	cellular response to thyroid hormone stimulus	Biological process	21217776
ITK	3702	IL2-inducible T-cell kinase	cytokine production	Biological process	-
ABL2	27	ABL proto-oncogene 2, non-receptor tyrosine kinase	ATP binding	Molecular function	-
ZFP36	7538	ZFP36 ring finger protein	response to starvation	Biological process	15014438
KRIT1	889	KRIT1, ankyrin repeat containing	negative regulation of endothelial cell migration	Biological process	20616044
APLP1	333	amyloid beta (A4) precursor-like protein 1	negative regulation of cAMP biosynthetic process	Biological process	16531006
OPTN	10133	optineurin	recycling endosome	Cellular component	-
RPS6KA1	6195	ribosomal protein S6 kinase, 90kDa, polypeptide 1	innate immune response	Biological process	-
LMX1B	4010	LIM homeobox transcription factor 1, beta	nucleus	Cellular component	10767331
TSPY4	728395	testis specific protein, Y-linked 4	spermatogenesis	Biological process	-
RQCD1	9125	RCD1 required for cell differentiation1 homolog (S. pombe)	transcription, DNA-templated	Biological process	-
PGLYRP2	114770	peptidoglycan recognition protein 2	membrane	Cellular component	11461926
FTL	2512	ferritin, light polypeptide	protein binding	Molecular function	16169070
HLTF	6596	helicase-like transcription factor	poly(A) RNA binding	Molecular function	22658674
PSMB3	5691	proteasome (prosome, macropain) subunit, beta type, 3	stimulatory C-type lectin receptor signaling pathway	Biological process	-
SOX11	6664	SRY (sex determining region Y)-box 11	translation factor activity, RNA binding	Molecular function	10606637
YWHAG	7532	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma	regulation of signal transduction	Biological process	10433554
ARHGEF2	9181	Rho/Rac guanine nucleotide exchange factor (GEF) 2	vesicle	Cellular component	21887730
JAK2	3717	Janus kinase 2	positive regulation of cell proliferation	Biological process	-
SPN	6693	sialophorin	chemotaxis	Biological process	10753822
EXOC5	10640	exocyst complex component 5	membrane organization	Biological process	-
RFWD2	64326	ring finger and WD repeat domain 2, E3 ubiquitin protein ligase	response to ionizing radiation	Biological process	19805145
PSMD5	5711	proteasome (prosome, macropain) 26S subunit, non-ATPase, 5	stimulatory C-type lectin receptor signaling pathway	Biological process	-
CTRB1	1504	chymotrypsinogen B1	extracellular space	Cellular component	-
SP140	11262	SP140 nuclear body protein	cytoplasm	Cellular component	-
RNF133	168433	ring finger protein 133	zinc ion binding	Molecular function	-
SPP1	6696	secreted phosphoprotein 1	inflammatory response	Biological process	-
FBXL3	26224	F-box and leucine-rich repeat protein 3	circadian rhythm	Biological process	-
RNF31	55072	ring finger protein 31	cytoplasmic side of plasma membrane	Cellular component	20614026
HIST1H4L	8368	histone cluster 1, H4l	nucleus	Cellular component	14585971
HIST2H2BE	8349	histone cluster 2, H2be	nucleosome assembly	Biological process	1469070
PLSCR1	5359	phospholipid scramblase 1	calcium ion binding	Molecular function	9218461
POLR3G	10622	polymerase (RNA) III (DNA directed) polypeptide G (32kD)	transcription initiation from RNA polymerase III promoter	Biological process	-
PSMD3	5709	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	programmed cell death	Biological process	-
SOCS5	9655	suppressor of cytokine signaling 5	epidermal growth factor receptor binding	Molecular function	-
SNRPD3	6634	small nuclear ribonucleoprotein D3 polypeptide 18kDa	mRNA 3'-end processing	Biological process	-
WNT9A	7483	wingless-type MMTV integration site family, member 9A	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	-
KDM4A	9682	lysine (K)-specific demethylase 4A	protein binding	Molecular function	16415788
E2F7	144455	E2F transcription factor 7	negative regulation of transcription involved in G1/S transition of mitotic cell cycle	Biological process	22802528
NIPBL	25836	Nipped-B homolog (Drosophila)	uterus morphogenesis	Biological process	19242925
CLOCK	9575	clock circadian regulator	core promoter sequence-specific DNA binding	Molecular function	-
WNT8A	7478	wingless-type MMTV integration site family, member 8A	palate development	Biological process	18413325
EIF2S3	1968	eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa	transmembrane transport	Biological process	-
JAG1	182	jagged 1	pulmonary artery morphogenesis	Biological process	9207787
SCG2	7857	secretogranin II	negative regulation of extrinsic apoptotic signaling pathway	Biological process	14970115
ZNF267	10308	zinc finger protein 267	transcription, DNA-templated	Biological process	-
IKBKG	8517	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	ubiquitin ligase complex	Cellular component	17314283
CEPT1	10390	choline/ethanolamine phosphotransferase 1	integral component of membrane	Cellular component	-
NFKBIB	4793	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	toll-like receptor 10 signaling pathway	Biological process	-
DSP	1832	desmoplakin	scaffold protein binding	Molecular function	10852826
IL1R1	3554	interleukin 1 receptor, type I	cell surface	Cellular component	-
SCX	642658	scleraxis basic helix-loop-helix transcription factor	deltoid tuberosity development	Biological process	-
ZNF16	7564	zinc finger protein 16	positive regulation of cell division	Biological process	-
SYDE1	85360	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)	GTPase activator activity	Molecular function	-
CASQ2	845	calsequestrin 2 (cardiac muscle)	intracellular	Cellular component	16908766
DYRK2	8445	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2	cellular response to DNA damage stimulus	Biological process	19965871
EEF2	1938	eukaryotic translation elongation factor 2	protein binding	Molecular function	19417104
TLX2	3196	T-cell leukemia homeobox 2	mesoderm formation	Biological process	-
THAP3	90326	THAP domain containing, apoptosis associated protein 3	protein binding	Molecular function	20200153
FOLH1	2346	folate hydrolase (prostate-specific membrane antigen) 1	metallopeptidase activity	Molecular function	-
FAP	2191	fibroblast activation protein, alpha	extracellular space	Cellular component	17317851
LMBRD1	55788	LMBR1 domain containing 1	cobalamin metabolic process	Biological process	-
FAM129B	64855	family with sequence similarity 129, member B	negative regulation of apoptotic process	Biological process	21148485
RPL5	6125	ribosomal protein L5	nucleolus	Cellular component	-
ACTRT3	84517	actin-related protein T3	cytoskeleton	Cellular component	-
WNT11	7481	wingless-type MMTV integration site family, member 11	bicellular tight junction assembly	Biological process	-
ELF5	2001	E74-like factor 5 (ets domain transcription factor)	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
HPS6	79803	Hermansky-Pudlak syndrome 6	membrane	Cellular component	19946888
THSD7B	80731	thrombospondin, type I, domain containing 7B	integral component of membrane	Cellular component	-
TBL1Y	90665	transducin (beta)-like 1, Y-linked	transcription regulatory region DNA binding	Molecular function	-
ZFHX3	463	zinc finger homeobox 3	mitochondrion	Cellular component	-
PPP1CA	5499	protein phosphatase 1, catalytic subunit, alpha isozyme	regulation of translational initiation by eIF2 alpha dephosphorylation	Biological process	-
PSMC6	5706	proteasome (prosome, macropain) 26S subunit, ATPase, 6	G1/S transition of mitotic cell cycle	Biological process	-
ARFIP2	23647	ADP-ribosylation factor interacting protein 2	plasma membrane	Cellular component	9312003
INPP5K	51763	inositol polyphosphate-5-phosphatase K	cellular response to tumor necrosis factor	Biological process	21712384
CYTIP	9595	cytohesin 1 interacting protein	nucleoplasm	Cellular component	-
DCK	1633	deoxycytidine kinase	nucleus	Cellular component	-
ADRA2A	150	adrenoceptor alpha 2A	negative regulation of norepinephrine secretion	Biological process	19477270
SLC37A2	219855	solute carrier family 37 (glucose-6-phosphate transporter), member 2	phosphate ion homeostasis	Biological process	-
HOMEZ	57594	homeobox and leucine zipper encoding	nucleolus	Cellular component	-
KIF2B	84643	kinesin family member 2B	regulation of chromosome segregation	Biological process	19060894
THEG	51298	theg spermatid protein	spermatogenesis	Biological process	-
NR1D1	9572	nuclear receptor subfamily 1, group D, member 1	heme binding	Molecular function	18006707
APOC1	341	apolipoprotein C-I	phosphatidylcholine-sterol O-acyltransferase activator activity	Molecular function	18992221
KMO	8564	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	cellular nitrogen compound metabolic process	Biological process	-
LRP6	4040	low density lipoprotein receptor-related protein 6	protein homodimerization activity	Molecular function	12897152
KRTAP9-2	83899	keratin associated protein 9-2	protein binding	Molecular function	25416956
PDXK	8566	pyridoxal (pyridoxine, vitamin B6) kinase	pyridoxal phosphate binding	Molecular function	16600635
ZNF568	374900	zinc finger protein 568	nucleus	Cellular component	-
TIPARP	25976	TCDD-inducible poly(ADP-ribose) polymerase	multicellular organismal metabolic process	Biological process	-
RPS14	6208	ribosomal protein S14	poly(A) RNA binding	Molecular function	22681889
BSPH1	100131137	binder of sperm protein homolog 1	single fertilization	Biological process	-
OTOP2	92736	otopetrin 2	integral component of membrane	Cellular component	-
P2RX6	9127	purinergic receptor P2X, ligand gated ion channel, 6	transport	Biological process	9242461
ATG5	9474	autophagy related 5	autophagosome assembly	Biological process	-
SRY	6736	sex determining region Y	male sex determination	Biological process	1695712
LIMS1	3987	LIM and senescent cell antigen-like domains 1	positive regulation of cell-substrate adhesion	Biological process	20926685
URB1	9875	URB1 ribosome biogenesis 1 homolog (S. cerevisiae)	biological_process	Biological process	-
CHMP2A	27243	charged multivesicular body protein 2A	establishment of protein localization	Biological process	23045692
KLHL4	56062	kelch-like family member 4	cytoskeleton	Cellular component	-
MAPK8	5599	mitogen-activated protein kinase 8	positive regulation of determination of dorsal identity	Biological process	-
HK3	3101	hexokinase 3 (white cell)	glucose transport	Biological process	-
NRG2	9542	neuregulin 2	receptor binding	Molecular function	9168114
CDC5L	988	cell division cycle 5-like	DNA replication factor A complex	Cellular component	24332808
IL1R1	3554	interleukin 1 receptor, type I	platelet-derived growth factor receptor binding	Molecular function	16477012
SLC11A1	6556	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1	positive regulation of interferon-gamma production	Biological process	-
PANX1	24145	pannexin 1	innate immune response	Biological process	-
SLU7	10569	SLU7 splicing factor homolog (S. cerevisiae)	RNA splicing, via transesterification reactions	Biological process	10197984
MAPK9	5601	mitogen-activated protein kinase 9	rhythmic process	Biological process	-
DEPTOR	64798	DEP domain containing MTOR-interacting protein	negative regulation of TOR signaling	Biological process	19446321
RAMP2	10266	receptor (G protein-coupled) activity modifying protein 2	positive regulation of gene expression	Biological process	18097473
MRPL44	65080	mitochondrial ribosomal protein L44	poly(A) RNA binding	Molecular function	22681889
SP140	11262	SP140 nuclear body protein	nuclear envelope	Cellular component	8695863
PTGIS	5740	prostaglandin I2 (prostacyclin) synthase	cellular response to hypoxia	Biological process	21296955
GUK1	2987	guanylate kinase 1	nucleobase-containing small molecule interconversion	Biological process	-
ADAM20	8748	ADAM metallopeptidase domain 20	metalloendopeptidase activity	Molecular function	-
ANO6	196527	anoctamin 6	positive regulation of phagocytosis, engulfment	Biological process	-
PLA2R1	22925	phospholipase A2 receptor 1, 180kDa	receptor activity	Molecular function	7721806
GOLPH3L	55204	golgi phosphoprotein 3-like	trans-Golgi network membrane	Cellular component	23345592
PIK3CG	5294	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	blood coagulation	Biological process	-
CRP	1401	C-reactive protein, pentraxin-related	inflammatory response	Biological process	10408362
TCAP	8557	titin-cap	FATZ binding	Molecular function	15582318
EPHB1	2047	EPH receptor B1	positive regulation of synapse assembly	Biological process	-
TARS	6897	threonyl-tRNA synthetase	extracellular exosome	Cellular component	20458337
ARID5B	84159	AT rich interactive domain 5B (MRF1-like)	muscle organ morphogenesis	Biological process	-
PSD4	23550	pleckstrin and Sec7 domain containing 4	vesicle-mediated transport	Biological process	-
ADAR	103	adenosine deaminase, RNA-specific	negative regulation of apoptotic process	Biological process	-
PTPN4	5775	protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)	cytoplasm	Cellular component	10940933
APOBEC3G	60489	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G	cytidine deaminase activity	Molecular function	17121840
TRAF6	7189	TNF receptor-associated factor 6, E3 ubiquitin protein ligase	protein K63-linked ubiquitination	Biological process	17135271
E2F3	1871	E2F transcription factor 3	core promoter binding	Molecular function	15735762
STRC	161497	stereocilin	stereocilium	Cellular component	-
SPTAN1	6709	spectrin, alpha, non-erythrocytic 1	programmed cell death	Biological process	-
GK	2710	glycerol kinase	protein binding	Molecular function	21988832
CDO1	1036	cysteine dioxygenase type 1	ferrous iron binding	Molecular function	-
SALL4	57167	spalt-like transcription factor 4	heterochromatin	Cellular component	-
GDI1	2664	GDP dissociation inhibitor 1	protein binding	Molecular function	11809807
PREB	10113	prolactin regulatory element binding	membrane organization	Biological process	-
ATP1A2	477	ATPase, Na+/K+ transporting, alpha 2 polypeptide	caveola	Cellular component	-
DLG4	1742	discs, large homolog 4 (Drosophila)	protein phosphatase binding	Molecular function	-
MMP25	64386	matrix metallopeptidase 25	inflammatory response	Biological process	10628838
DHX16	8449	DEAH (Asp-Glu-Ala-His) box polypeptide 16	RNA splicing	Biological process	-
RND2	8153	Rho family GTPase 2	small GTPase mediated signal transduction	Biological process	-
PARK7	11315	parkinson protein 7	mitochondrion	Cellular component	21785459
ITGB1	3688	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	integrin alpha2-beta1 complex	Cellular component	24823363
KCNIP3	30818	Kv channel interacting protein 3, calsenilin	signal transduction	Biological process	10900016
BANF1	8815	barrier to autointegration factor 1	cytosol	Cellular component	-
FLOT1	10211	flotillin 1	cytoplasmic vesicle	Cellular component	23983584
NCKAP1L	3071	NCK-associated protein 1-like	positive regulation of CD4-positive, alpha-beta T cell differentiation	Biological process	-
MAN1A1	4121	mannosidase, alpha, class 1A, member 1	calcium ion binding	Molecular function	-
ACTB	60	actin, beta	focal adhesion	Cellular component	21423176
FGFR1OP	11116	FGFR1 oncogene partner	protein tyrosine kinase inhibitor activity	Molecular function	17888034
GPR78	27201	G protein-coupled receptor 78	adenylate cyclase-activating G-protein coupled receptor signaling pathway	Biological process	17363172
FDXR	2232	ferredoxin reductase	oxidation-reduction process	Biological process	-
NLRC5	84166	NLR family, CARD domain containing 5	negative regulation of NF-kappaB transcription factor activity	Biological process	20434986
DACT3	147906	dishevelled-binding antagonist of beta-catenin 3	negative regulation of canonical Wnt signaling pathway	Biological process	-
VDR	7421	vitamin D (1,25- dihydroxyvitamin D3) receptor	RNA polymerase II transcription factor complex	Cellular component	17426122
LRR1	122769	leucine rich repeat protein 1	protein ubiquitination	Biological process	-
WNT3A	89780	wingless-type MMTV integration site family, member 3A	negative regulation of heart induction by canonical Wnt signaling pathway	Biological process	19736317
DMTN	2039	dematin actin binding protein	regulation of lamellipodium assembly	Biological process	10565303
OR5D16	390144	olfactory receptor, family 5, subfamily D, member 16	G-protein coupled receptor activity	Molecular function	-
LAMA2	3908	laminin, alpha 2	regulation of cell adhesion	Biological process	-
TIPARP	25976	TCDD-inducible poly(ADP-ribose) polymerase	nitrogen compound metabolic process	Biological process	-
ACSS3	79611	acyl-CoA synthetase short-chain family member 3	metabolic process	Biological process	-
PPM1G	5496	protein phosphatase, Mg2+/Mn2+ dependent, 1G	cytoplasm	Cellular component	-
TP53	7157	tumor protein p53	negative regulation of helicase activity	Biological process	7663514
RPA1	6117	replication protein A1, 70kDa	post-translational protein modification	Biological process	-
SOX9	6662	SRY (sex determining region Y)-box 9	oligodendrocyte differentiation	Biological process	-
TRAP1	10131	TNF receptor-associated protein 1	lipid particle	Cellular component	-
TRIM32	22954	tripartite motif containing 32	translation initiation factor binding	Molecular function	-
SOX8	30812	SRY (sex determining region Y)-box 8	negative regulation of photoreceptor cell differentiation	Biological process	-
CLPB	81570	ClpB homolog, mitochondrial AAA ATPase chaperonin	cellular_component	Cellular component	-
ZFPM1	161882	zinc finger protein, FOG family member 1	platelet formation	Biological process	11675338
DEFB119	245932	defensin, beta 119	cell surface	Cellular component	-
ZDHHC13	54503	zinc finger, DHHC-type containing 13	endoplasmic reticulum	Cellular component	16647879
CYP17A1	1586	cytochrome P450, family 17, subfamily A, polypeptide 1	response to insecticide	Biological process	-
MPHOSPH8	54737	M-phase phosphoprotein 8	extracellular exosome	Cellular component	23376485
DPPA2	151871	developmental pluripotency associated 2	chromatin binding	Molecular function	-
FRAT2	23401	frequently rearranged in advanced T-cell lymphomas 2	multicellular organismal development	Biological process	9635432
SYT17	51760	synaptotagmin XVII	positive regulation of dendrite extension	Biological process	23999003
BLOC1S3	388552	biogenesis of lysosomal organelles complex-1, subunit 3	protein binding	Molecular function	15102850
HORMAD1	84072	HORMA domain containing 1	meiotic sister chromatid cohesion	Biological process	-
TAF6	6878	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa	protein heterodimerization activity	Molecular function	-
CLN8	2055	ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)	neuromuscular process controlling posture	Biological process	-
SP140L	93349	SP140 nuclear body protein-like	chromatin binding	Molecular function	-
SFRP5	6425	secreted frizzled-related protein 5	integral component of membrane	Cellular component	-
ATG4C	84938	autophagy related 4C, cysteine peptidase	cytosol	Cellular component	12446702
PPP1R18	170954	protein phosphatase 1, regulatory subunit 18	actin binding	Molecular function	-
PDIA2	64714	protein disulfide isomerase family A, member 2	protein folding in endoplasmic reticulum	Biological process	22013210
CCL21	6366	chemokine (C-C motif) ligand 21	activation of GTPase activity	Biological process	15778365
DGCR8	54487	DGCR8 microprocessor complex subunit	nucleus	Cellular component	15574589
PARP10	84875	poly (ADP-ribose) polymerase family, member 10	negative regulation of gene expression	Biological process	23575687
AIP	9049	aryl hydrocarbon receptor interacting protein	regulation of nucleic acid-templated transcription	Biological process	9447995
ATP10D	57205	ATPase, class V, type 10D	ion transmembrane transport	Biological process	-
FOXP2	93986	forkhead box P2	metal ion binding	Molecular function	-
HERPUD1	9709	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	protein binding	Molecular function	18307982
FOXN1	8456	forkhead box N1	transcription from RNA polymerase II promoter	Biological process	10767081
OLFM3	118427	olfactomedin 3	cell junction	Cellular component	-
GGPS1	9453	geranylgeranyl diphosphate synthase 1	geranylgeranyl diphosphate biosynthetic process	Biological process	-
APOM	55937	apolipoprotein M	reverse cholesterol transport	Biological process	15793583
POLR3G	10622	polymerase (RNA) III (DNA directed) polypeptide G (32kD)	nuclear chromatin	Cellular component	24107381
CASP2	835	caspase 2, apoptosis-related cysteine peptidase	regulation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	-
ZNF20	7568	zinc finger protein 20	regulation of transcription, DNA-templated	Biological process	-
SLC35B2	347734	solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2	Golgi membrane	Cellular component	-
POLR3H	171568	polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)	innate immune response	Biological process	-
SRGAP2	23380	SLIT-ROBO Rho GTPase activating protein 2	negative regulation of neuron migration	Biological process	22559944
RPL8	6132	ribosomal protein L8	viral transcription	Biological process	-
Mar-01	64757	mitochondrial amidoxime reducing component 1	mitochondrial inner membrane	Cellular component	-
CALR	811	calreticulin	negative regulation of intracellular steroid hormone receptor signaling pathway	Biological process	8107809
YY1	7528	YY1 transcription factor	transcription corepressor activity	Molecular function	1655281
JAG2	3714	jagged 2	morphogenesis of embryonic epithelium	Biological process	-
ADAM19	8728	ADAM metallopeptidase domain 19	membrane protein ectodomain proteolysis	Biological process	-
WNT8B	7479	wingless-type MMTV integration site family, member 8B	positive regulation of canonical Wnt signaling pathway	Biological process	-
MAP1LC3C	440738	microtubule-associated protein 1 light chain 3 gamma	mitochondrion degradation	Biological process	-
ABCB5	340273	ATP-binding cassette, sub-family B (MDR/TAP), member 5	metabolic process	Biological process	-
SSR1	6745	signal sequence receptor, alpha	endoplasmic reticulum membrane	Cellular component	-
SELE	6401	selectin E	response to lipopolysaccharide	Biological process	18029551
CLIC4	25932	chloride intracellular channel 4	nuclear matrix	Cellular component	14569596
SMAD7	4092	SMAD family member 7	intracellular signal transduction	Biological process	-
TFDP3	51270	transcription factor Dp family, member 3	protein heterodimerization activity	Molecular function	17062573
SMAD9	4093	SMAD family member 9	cytosol	Cellular component	-
ARHGEF4	50649	Rho guanine nucleotide exchange factor (GEF) 4	small GTPase mediated signal transduction	Biological process	-
TBX6	6911	T-box 6	somite rostral/caudal axis specification	Biological process	-
S100A8	6279	S100 calcium binding protein A8	extracellular space	Cellular component	16502470
GRB2	2885	growth factor receptor-bound protein 2	plasma membrane	Cellular component	-
MAP4K4	9448	mitogen-activated protein kinase kinase kinase kinase 4	cytoplasm	Cellular component	14966141
HCRTR2	3062	hypocretin (orexin) receptor 2	integral component of plasma membrane	Cellular component	9491897
ADCY10	55811	adenylate cyclase 10 (soluble)	magnesium ion binding	Molecular function	-
OR51I2	390064	olfactory receptor, family 51, subfamily I, member 2	detection of chemical stimulus involved in sensory perception of smell	Biological process	11121057
GPER1	2852	G protein-coupled estrogen receptor 1	intracellular	Cellular component	-
GJA1	2697	gap junction protein, alpha 1, 43kDa	endoplasmic reticulum membrane	Cellular component	-
MARS2	92935	methionyl-tRNA synthetase 2, mitochondrial	ATP binding	Molecular function	-
NPM1	4869	nucleophosmin (nucleolar phosphoprotein B23, numatrin)	positive regulation of translation	Biological process	12882984
DGKA	1606	diacylglycerol kinase, alpha 80kDa	ATP binding	Molecular function	-
TLR2	7097	toll-like receptor 2	nitric oxide metabolic process	Biological process	-
CDSN	1041	corneodesmosin	skin morphogenesis	Biological process	20691404
PAK4	10298	p21 protein (Cdc42/Rac)-activated kinase 4	protein serine/threonine kinase activity	Molecular function	-
ZNF558	148156	zinc finger protein 558	DNA binding	Molecular function	-
BIRC8	112401	baculoviral IAP repeat containing 8	neuron apoptotic process	Biological process	-
OR10AD1	121275	olfactory receptor, family 10, subfamily AD, member 1	plasma membrane	Cellular component	-
HIRA	7290	histone cell cycle regulator	nucleus	Cellular component	-
MYO5B	4645	myosin VB	Rab GTPase binding	Molecular function	17462998
MISP	126353	mitotic spindle positioning	cell division	Biological process	-
PSMD3	5709	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	Biological process	-
ZNF653	115950	zinc finger protein 653	DNA binding	Molecular function	-
DST	667	dystonin	nuclear envelope	Cellular component	-
APOA1	335	apolipoprotein A-I	positive regulation of Rho protein signal transduction	Biological process	23726972
POR	5447	P450 (cytochrome) oxidoreductase	enzyme binding	Molecular function	-
CITED1	4435	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1	response to interleukin-11	Biological process	-
ALG8	79053	ALG8, alpha-1,3-glucosyltransferase	protein N-linked glycosylation	Biological process	12480927
AKAP3	10566	A kinase (PRKA) anchor protein 3	nucleus	Cellular component	21630459
OPCML	4978	opioid binding protein/cell adhesion molecule-like	cell adhesion	Biological process	7721093
RPS27A	6233	ribosomal protein S27a	cytokine-mediated signaling pathway	Biological process	-
VIL1	7429	villin 1	cellular response to epidermal growth factor stimulus	Biological process	17229814
RIPK1	8737	receptor (TNFRSF)-interacting serine-threonine kinase 1	protein heterooligomerization	Biological process	22817896
PER2	8864	period circadian clock 2	transcription factor binding transcription factor activity	Molecular function	-
CLOCK	9575	clock circadian regulator	negative regulation of transcription, DNA-templated	Biological process	-
PICK1	9463	protein interacting with PRKCA 1	Golgi apparatus	Cellular component	-
HLA-DPB1	3115	major histocompatibility complex, class II, DP beta 1	membrane	Cellular component	19946888
CASP3	836	caspase 3, apoptosis-related cysteine peptidase	plasma membrane	Cellular component	-
HFE	3077	hemochromatosis	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	24904118
USP13	8975	ubiquitin specific peptidase 13 (isopeptidase T-3)	ubiquitin protein ligase binding	Molecular function	21659512
MMP9	4318	matrix metallopeptidase 9	ossification	Biological process	-
SOAT2	8435	sterol O-acyltransferase 2	brush border	Cellular component	14615411
GPI	2821	glucose-6-phosphate isomerase	humoral immune response	Biological process	3020690
ADIG	149685	adipogenin	nucleus	Cellular component	15567149
SNRNP200	23020	small nuclear ribonucleoprotein 200kDa (U5)	ATP-dependent helicase activity	Molecular function	9539711
PFDN5	5204	prefoldin subunit 5	regulation of transcription, DNA-templated	Biological process	9792694
HIST1H2BF	8343	histone cluster 1, H2bf	antibacterial humoral response	Biological process	12860195
CHAD	1101	chondroadherin	bone development	Biological process	-
WDR4	10785	WD repeat domain 4	nucleoplasm	Cellular component	-
DVL1	1855	dishevelled segment polarity protein 1	cytoplasm	Cellular component	-
ANAPC1	64682	anaphase promoting complex subunit 1	protein K11-linked ubiquitination	Biological process	18485873
SLPI	6590	secretory leukocyte peptidase inhibitor	extracellular matrix	Cellular component	20551380
PIK3R6	146850	phosphoinositide-3-kinase, regulatory subunit 6	blood coagulation	Biological process	-
PLAC9	219348	placenta-specific 9	protein binding	Molecular function	25416956
ARX	170302	aristaless related homeobox	cerebral cortex GABAergic interneuron migration	Biological process	-
PES1	23481	pescadillo ribosomal biogenesis factor 1	nucleoplasm	Cellular component	16738141
TRPC3	7222	transient receptor potential cation channel, subfamily C, member 3	ion transmembrane transport	Biological process	-
RPL27A	6157	ribosomal protein L27a	translational termination	Biological process	-
WWP2	11060	WW domain containing E3 ubiquitin protein ligase 2	negative regulation of transporter activity	Biological process	18776082
STAT3	6774	signal transducer and activator of transcription 3 (acute-phase response factor)	eating behavior	Biological process	-
DNASE1L3	1776	deoxyribonuclease I-like 3	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	Molecular function	-
ASIC1	41	acid sensing (proton gated) ion channel 1	calcium ion transmembrane transport	Biological process	-
P2RX7	5027	purinergic receptor P2X, ligand gated ion channel, 7	regulation of killing of cells of other organism	Biological process	17785580
PPARD	5467	peroxisome proliferator-activated receptor delta	wound healing	Biological process	-
PDE6H	5149	phosphodiesterase 6H, cGMP-specific, cone, gamma	enzyme inhibitor activity	Molecular function	8786098
GZMM	3004	granzyme M (lymphocyte met-ase 1)	apoptotic process	Biological process	-
PFKL	5211	phosphofructokinase, liver	6-phosphofructokinase complex	Cellular component	6444532
ERCC2	2068	excision repair cross-complementation group 2	response to hypoxia	Biological process	-
CRYBG3	131544	beta-gamma crystallin domain containing 3	carbohydrate binding	Molecular function	-
DAXX	1616	death-domain associated protein	PML body	Cellular component	15247905
DDIT3	1649	DNA-damage-inducible transcript 3	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	22065586
DGKD	8527	diacylglycerol kinase, delta 130kDa	protein homooligomerization	Biological process	12200442
UNC93B1	81622	unc-93 homolog B1 (C. elegans)	toll-like receptor 9 signaling pathway	Biological process	19006693
IFNA2	3440	interferon, alpha 2	positive regulation of peptidyl-serine phosphorylation of STAT protein	Biological process	-
ABHD11	83451	abhydrolase domain containing 11	cellular_component	Cellular component	-
RAB37	326624	RAB37, member RAS oncogene family	regulation of exocytosis	Biological process	-
PTPN1	5770	protein tyrosine phosphatase, non-receptor type 1	enzyme binding	Molecular function	22169477
LOC400927-CSNK1E	102800317	LOC400927-CSNK1E readthrough	regulation of cell shape	Biological process	-
CXADR	1525	coxsackie virus and adenovirus receptor	integral component of plasma membrane	Cellular component	9096397
UBR4	23352	ubiquitin protein ligase E3 component n-recognin 4	viral process	Biological process	-
MTMR4	9110	myotubularin related protein 4	protein dephosphorylation	Biological process	9736772
CABLES1	91768	Cdk5 and Abl enzyme substrate 1	nucleus	Cellular component	-
CDKN1B	1027	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	positive regulation of microtubule polymerization	Biological process	-
GH2	2689	growth hormone 2	extracellular region	Cellular component	-
ADRBK1	156	adrenergic, beta, receptor kinase 1	ATP binding	Molecular function	-
CXCR2	3579	chemokine (C-X-C motif) receptor 2	chemotaxis	Biological process	10725748
DERL1	79139	derlin 1	positive regulation of protein ubiquitination	Biological process	24089527
FANCI	55215	Fanconi anemia, complementation group I	positive regulation of protein ubiquitination	Biological process	18029348
ZSCAN30	100101467	zinc finger and SCAN domain containing 30	regulation of transcription, DNA-templated	Biological process	-
CRY2	1408	cryptochrome circadian clock 2	glucose homeostasis	Biological process	-
SMG1	23049	SMG1 phosphatidylinositol 3-kinase-related kinase	protein binding	Molecular function	11544179
CASP6	839	caspase 6, apoptosis-related cysteine peptidase	proteolysis	Biological process	12888622
TAF1B	9014	TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa	termination of RNA polymerase I transcription	Biological process	-
MXI1	4601	MAX interactor 1, dimerization protein	nucleolus	Cellular component	-
DDX3X	1654	DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked	protein binding	Molecular function	10074132
BCL2L1	598	BCL2-like 1	apoptotic process in bone marrow	Biological process	-
VNN3	55350	vanin 3	biological_process	Biological process	-
MAPRE2	10982	microtubule-associated protein, RP/EB family, member 2	cell proliferation	Biological process	9233623
CEP162	22832	centrosomal protein 162kDa	nucleoplasm	Cellular component	-
PRKD1	5587	protein kinase D1	positive regulation of peptidyl-serine phosphorylation	Biological process	20497126
MOS	4342	v-mos Moloney murine sarcoma viral oncogene homolog	activation of MAPKK activity	Biological process	-
WNT1	7471	wingless-type MMTV integration site family, member 1	midbrain development	Biological process	-
MAPT	4137	microtubule-associated protein tau	regulation of microtubule-based movement	Biological process	-
NCAM1	4684	neural cell adhesion molecule 1	integral component of membrane	Cellular component	-
UTRN	7402	utrophin	plasma membrane	Cellular component	-
WNT1	7471	wingless-type MMTV integration site family, member 1	ubiquitin-dependent SMAD protein catabolic process	Biological process	-
SIK1	150094	salt-inducible kinase 1	nucleus	Cellular component	16306228
CCIN	881	calicin	nucleus	Cellular component	21630459
NLRP12	91662	NLR family, pyrin domain containing 12	negative regulation of cytokine secretion	Biological process	16203735
ROS1	6098	ROS proto-oncogene 1 , receptor tyrosine kinase	spermatogenesis	Biological process	-
ZCCHC4	29063	zinc finger, CCHC domain containing 4	methylation	Biological process	-
PRKD1	5587	protein kinase D1	regulation of keratinocyte proliferation	Biological process	-
TLX1	3195	T-cell leukemia homeobox 1	cell fate commitment	Biological process	-
FXYD1	5348	FXYD domain containing ion transport regulator 1	transmembrane transport	Biological process	-
KCTD3	51133	potassium channel tetramerization domain containing 3	protein homooligomerization	Biological process	-
PRDX2	7001	peroxiredoxin 2	negative regulation of neuron apoptotic process	Biological process	-
UMPS	7372	uridine monophosphate synthetase	orotate phosphoribosyltransferase activity	Molecular function	-
TAF1	6872	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa	protein serine/threonine kinase activity	Molecular function	15053879
RABEP1	9135	rabaptin, RAB GTPase binding effector protein 1	apoptotic process	Biological process	-
EGFR	1956	epidermal growth factor receptor	salivary gland morphogenesis	Biological process	-
ZP3	7784	zona pellucida glycoprotein 3 (sperm receptor)	positive regulation of type IV hypersensitivity	Biological process	-
DHX38	9785	DEAH (Asp-Glu-Ala-His) box polypeptide 38	mRNA 3'-end processing	Biological process	-
CASC5	57082	cancer susceptibility candidate 5	nucleosome assembly	Biological process	-
Mar-01	64757	mitochondrial amidoxime reducing component 1	nitrate reductase activity	Molecular function	20861021
ATRN	8455	attractin	pigmentation	Biological process	-
CASP7	840	caspase 7, apoptosis-related cysteine peptidase	nucleoplasm	Cellular component	-
NPPB	4879	natriuretic peptide B	receptor binding	Molecular function	12727915
CTNNA3	29119	catenin (cadherin-associated protein), alpha 3	cytoplasm	Cellular component	-
PSIP1	11168	PC4 and SFRS1 interacting protein 1	transcription, DNA-templated	Biological process	-
FH	2271	fumarate hydratase	extracellular exosome	Cellular component	20458337
LYN	4067	LYN proto-oncogene, Src family tyrosine kinase	ubiquitin protein ligase binding	Molecular function	-
S100A13	6284	S100 calcium binding protein A13	cytosol	Cellular component	12746488
PLAT	5327	plasminogen activator, tissue	platelet-derived growth factor receptor signaling pathway	Biological process	-
SHANK2	22941	SH3 and multiple ankyrin repeat domains 2	photoreceptor outer segment	Cellular component	-
SIRT1	23411	sirtuin 1	positive regulation of macrophage apoptotic process	Biological process	-
CTNNA1	1495	catenin (cadherin-associated protein), alpha 1, 102kDa	actin filament binding	Molecular function	-
WDR3	10885	WD repeat domain 3	nucleus	Cellular component	-
TXNRD1	7296	thioredoxin reductase 1	mesoderm formation	Biological process	-
ERCC8	1161	excision repair cross-complementation group 8	protein complex binding	Molecular function	16916636
BGN	633	biglycan	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan	Biological process	-
ODF2	4957	outer dense fiber of sperm tails 2	protein binding	Molecular function	16980960
CD81	975	CD81 molecule	receptor-mediated virion attachment to host cell	Biological process	14676841
BDNF	627	brain-derived neurotrophic factor	cytoplasm	Cellular component	-
TMEM35	59353	transmembrane protein 35	peroxisomal membrane	Cellular component	-
PSMC2	5701	proteasome (prosome, macropain) 26S subunit, ATPase, 2	protein polyubiquitination	Biological process	-
CUBN	8029	cubilin (intrinsic factor-cobalamin receptor)	cobalamin metabolic process	Biological process	-
JPH4	84502	junctophilin 4	calcium ion transport into cytosol	Biological process	19095005
PLCH1	23007	phospholipase C, eta 1	calcium-dependent phospholipase C activity	Molecular function	15702972
MALT1	10892	MALT1 paracaspase	activation of NF-kappaB-inducing kinase activity	Biological process	15125833
DLL4	54567	delta-like 4 (Drosophila)	integral component of membrane	Cellular component	-
EMG1	10436	EMG1 N1-specific pseudouridine methyltransferase	poly(A) RNA binding	Molecular function	22658674
TBXA2R	6915	thromboxane A2 receptor	positive regulation of GTPase activity	Biological process	-
HPR	3250	haptoglobin-related protein	hemoglobin binding	Molecular function	2987228
NCOA1	8648	nuclear receptor coactivator 1	ligand-dependent nuclear receptor binding	Molecular function	17363140
DUSP3	1845	dual specificity phosphatase 3	toll-like receptor TLR1:TLR2 signaling pathway	Biological process	-
CREB1	1385	cAMP responsive element binding protein 1	circadian rhythm	Biological process	-
EMG1	10436	EMG1 N1-specific pseudouridine methyltransferase	cytoplasm	Cellular component	-
CIT	11113	citron rho-interacting serine/threonine kinase	generation of neurons	Biological process	11086988
REEP2	51308	receptor accessory protein 2	regulation of intracellular transport	Biological process	-
HIF3A	64344	hypoxia inducible factor 3, alpha subunit	mitochondrion	Cellular component	-
ENO1	2023	enolase 1, (alpha)	carbohydrate metabolic process	Biological process	-
ACP2	53	acid phosphatase 2, lysosomal	integral component of membrane	Cellular component	-
ZBED4	9889	zinc finger, BED-type containing 4	cytoplasm	Cellular component	19369242
FAM63A	55793	family with sequence similarity 63, member A	extracellular exosome	Cellular component	23376485
DBN1	1627	drebrin 1	regulation of neuronal synaptic plasticity	Biological process	12009525
INSM1	3642	insulinoma-associated 1	regulation of protein complex assembly	Biological process	19124461
DCAF13	25879	DDB1 and CUL4 associated factor 13	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Biological process	-
STOX2	56977	storkhead box 2	cellular_component	Cellular component	-
ARSB	411	arylsulfatase B	glycosphingolipid metabolic process	Biological process	-
GRM8	2918	glutamate receptor, metabotropic 8	visual perception	Biological process	9473604
RBCK1	10616	RanBP-type and C3HC4-type zinc finger containing 1	negative regulation of necroptotic process	Biological process	-
PXK	54899	PX domain containing serine/threonine kinase	microtubule organizing center	Cellular component	-
PFKFB2	5208	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2	fructose-2,6-bisphosphate 2-phosphatase activity	Molecular function	-
ARID5B	84159	AT rich interactive domain 5B (MRF1-like)	female gonad development	Biological process	-
RAB27A	5873	RAB27A, member RAS oncogene family	positive regulation of gene expression	Biological process	23092844
TRIM48	79097	tripartite motif containing 48	zinc ion binding	Molecular function	-
ERCC2	2068	excision repair cross-complementation group 2	transcription from RNA polymerase I promoter	Biological process	-
TCP10L	140290	t-complex 10-like	negative regulation of transcription from RNA polymerase II promoter	Biological process	14586771
NR1H4	9971	nuclear receptor subfamily 1, group H, member 4	chenodeoxycholic acid binding	Molecular function	10334992
REST	5978	RE1-silencing transcription factor	negative regulation of insulin secretion	Biological process	20942606
ESPN	83715	espin	SH3 domain binding	Molecular function	12598619
CALR	811	calreticulin	protein maturation by protein folding	Biological process	17563366
OSBPL5	114879	oxysterol binding protein-like 5	oxysterol binding	Molecular function	10588946
SNRPA1	6627	small nuclear ribonucleoprotein polypeptide A'	poly(A) RNA binding	Molecular function	22681889
CPNE3	8895	copine III	calcium-dependent phospholipid binding	Molecular function	11041869
NOTCH2	4853	notch 2	inflammatory response to antigenic stimulus	Biological process	-
B3GAT1	27087	beta-1,3-glucuronyltransferase 1	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity	Molecular function	-
RBP4	5950	retinol binding protein 4, plasma	eye development	Biological process	-
GEM	2669	GTP binding protein overexpressed in skeletal muscle	small GTPase mediated signal transduction	Biological process	-
GLIPR2	152007	GLI pathogenesis-related 2	positive regulation of epithelial to mesenchymal transition	Biological process	23516513
SPAG8	26206	sperm associated antigen 8	biological_process	Biological process	-
FKBP1B	2281	FK506 binding protein 1B, 12.6 kDa	regulation of ryanodine-sensitive calcium-release channel activity	Biological process	7592869
AGO4	192670	argonaute RISC catalytic component 4	fibroblast growth factor receptor signaling pathway	Biological process	-
ELL3	80237	elongation factor RNA polymerase II-like 3	positive regulation of neural precursor cell proliferation	Biological process	-
RAB30	27314	RAB30, member RAS oncogene family	cytoplasm	Cellular component	-
SLC25A16	8034	solute carrier family 25 (mitochondrial carrier), member 16	transmembrane transport	Biological process	-
EGLN2	112398	egl-9 family hypoxia-inducible factor 2	L-ascorbic acid binding	Molecular function	-
ASPN	54829	asporin	proteinaceous extracellular matrix	Cellular component	17827158
ITGB1BP1	9270	integrin beta 1 binding protein 1	ruffle	Cellular component	11919189
DDO	8528	D-aspartate oxidase	cofactor binding	Molecular function	20603179
PINK1	65018	PTEN induced putative kinase 1	negative regulation of oxidative stress-induced neuron death	Biological process	24522549
KIF2B	84643	kinesin family member 2B	microtubule binding	Molecular function	-
SOX13	9580	SRY (sex determining region Y)-box 13	anatomical structure morphogenesis	Biological process	10198172
COL1A2	1278	collagen, type I, alpha 2	collagen catabolic process	Biological process	-
PIF1	80119	PIF1 5'-to-3' DNA helicase	regulation of telomere maintenance	Biological process	16522649
STAMBP	10617	STAM binding protein	plasma membrane	Cellular component	-
NPFF	8620	neuropeptide FF-amide peptide precursor	cytosol	Cellular component	-
HEY1	23462	hes-related family bHLH transcription factor with YRPW motif 1	protein dimerization activity	Molecular function	-
RPL35	11224	ribosomal protein L35	translational initiation	Biological process	-
ZNF367	195828	zinc finger protein 367	nucleus	Cellular component	15344908
SMAD2	4087	SMAD family member 2	I-SMAD binding	Molecular function	9256479
TWF1	5756	twinfilin actin-binding protein 1	focal adhesion	Cellular component	21423176
GGT7	2686	gamma-glutamyltransferase 7	glutathione hydrolase activity	Molecular function	-
PARP10	84875	poly (ADP-ribose) polymerase family, member 10	negative regulation of fibroblast proliferation	Biological process	15674325
PAX3	5077	paired box 3	positive regulation of transcription from RNA polymerase II promoter	Biological process	11863357
GM2A	2760	GM2 ganglioside activator	extracellular exosome	Cellular component	19056867
NEUROD1	4760	neuronal differentiation 1	nucleocytoplasmic transport	Biological process	-
CHRNB2	1141	cholinergic receptor, nicotinic, beta 2 (neuronal)	calcium ion transport	Biological process	-
SOX9	6662	SRY (sex determining region Y)-box 9	regulation of cell proliferation	Biological process	-
TRIM32	22954	tripartite motif containing 32	cytosol	Cellular component	-
TRIM24	8805	tripartite motif containing 24	regulation of signal transduction by p53 class mediator	Biological process	-
EHD1	10938	EH-domain containing 1	positive regulation of myoblast fusion	Biological process	-
MMP9	4318	matrix metallopeptidase 9	negative regulation of intrinsic apoptotic signaling pathway	Biological process	22984561
IPO5	3843	importin 5	ribosomal protein import into nucleus	Biological process	9687515
ADRM1	11047	adhesion regulating molecule 1	cytoplasm	Cellular component	-
TC2N	123036	tandem C2 domains, nuclear	calcium-dependent phospholipid binding	Molecular function	-
RNPS1	10921	RNA binding protein S1, serine-rich domain	regulation of alternative mRNA splicing, via spliceosome	Biological process	22203037
NME6	10201	NME/NM23 nucleoside diphosphate kinase 6	GTP biosynthetic process	Biological process	-
AREG	374	amphiregulin	glial cell proliferation	Biological process	-
PER3	8863	period circadian clock 3	circadian regulation of gene expression	Biological process	-
VEGFC	7424	vascular endothelial growth factor C	vascular endothelial growth factor receptor signaling pathway	Biological process	-
SMC3	9126	structural maintenance of chromosomes 3	mediator complex binding	Molecular function	-
GPN2	54707	GPN-loop GTPase 2	metabolic process	Biological process	-
EPB41L3	23136	erythrocyte membrane protein band 4.1-like 3	paranodal junction assembly	Biological process	-
BRSK2	9024	BR serine/threonine kinase 2	ATP binding	Molecular function	14976552
NRP1	8829	neuropilin 1	coronary artery morphogenesis	Biological process	-
INHBB	3625	inhibin, beta B	cell differentiation	Biological process	10320815
TADA3	10474	transcriptional adaptor 3	STAGA complex	Cellular component	11564863
IGLC3	3539	immunoglobulin lambda constant 3 (Kern-Oz+ marker)	antigen binding	Molecular function	-
RAB40AL	282808	RAB40A, member RAS oncogene family-like	intracellular protein transport	Biological process	-
CHEK2	11200	checkpoint kinase 2	double-strand break repair	Biological process	18317453
RBMY1J	378951	RNA binding motif protein, Y-linked, family 1, member J	RNA splicing	Biological process	-
ITPRIPL1	150771	inositol 1,4,5-trisphosphate receptor interacting protein-like 1	integral component of membrane	Cellular component	-
DPEP1	1800	dipeptidase 1 (renal)	homocysteine metabolic process	Biological process	20031578
PPAP2A	8611	phosphatidic acid phosphatase type 2A	regulation of lipid metabolic process	Biological process	9468526
MARVELD2	153562	MARVEL domain containing 2	basolateral plasma membrane	Cellular component	23073616
SNF8	11267	SNF8, ESCRT-II complex subunit	protein homodimerization activity	Molecular function	14505570
ING5	84289	inhibitor of growth family, member 5	histone H3 acetylation	Biological process	16387653
DAZL	1618	deleted in azoospermia-like	cytoplasm	Cellular component	-
NRG2	9542	neuregulin 2	innate immune response	Biological process	-
PCDHA7	56141	protocadherin alpha 7	cell adhesion	Biological process	10380929
WNT4	54361	wingless-type MMTV integration site family, member 4	non-canonical Wnt signaling pathway via MAPK cascade	Biological process	17720811
TEAD3	7005	TEA domain family member 3	gene expression	Biological process	-
TFAP2A	7020	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	face morphogenesis	Biological process	-
VDAC3	7419	voltage-dependent anion channel 3	porin activity	Molecular function	-
NDRG4	65009	NDRG family member 4	endoplasmic reticulum membrane	Cellular component	-
MUC16	94025	mucin 16, cell surface associated	post-translational protein modification	Biological process	-
CD74	972	CD74 molecule, major histocompatibility complex, class II invariant chain	identical protein binding	Molecular function	12782713
HCN1	348980	hyperpolarization activated cyclic nucleotide gated potassium channel 1	potassium ion transport	Biological process	9405696
GFRA1	2674	GDNF family receptor alpha 1	anchored component of membrane	Cellular component	-
PCSK5	5125	proprotein convertase subtilisin/kexin type 5	nerve growth factor processing	Biological process	-
VANGL1	81839	VANGL planar cell polarity protein 1	protein binding	Molecular function	15205336
OR8J1	219477	olfactory receptor, family 8, subfamily J, member 1	plasma membrane	Cellular component	-
SCUBE3	222663	signal peptide, CUB domain, EGF-like 3	protein homooligomerization	Biological process	15234972
ALOX12	239	arachidonate 12-lipoxygenase	reactive oxygen species metabolic process	Biological process	12858336
MCU	90550	mitochondrial calcium uniporter	glucose homeostasis	Biological process	22829870
OR1A1	8383	olfactory receptor, family 1, subfamily A, member 1	G-protein coupled receptor activity	Molecular function	-
WBSCR27	155368	Williams Beuren syndrome chromosome region 27	protein binding	Molecular function	25814554
ALPK3	57538	alpha-kinase 3	heart development	Biological process	-
ZNF592	9640	zinc finger protein 592	nucleoplasm	Cellular component	-
KCNAB3	9196	potassium channel, voltage gated subfamily A regulatory beta subunit 3	potassium channel regulator activity	Molecular function	9857044
ZFP62	643836	ZFP62 zinc finger protein	metal ion binding	Molecular function	-
USP14	9097	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)	regulation of chemotaxis	Biological process	19106094
MUC3A	4584	mucin 3A, cell surface associated	protein O-linked glycosylation	Biological process	-
SLC17A7	57030	solute carrier family 17 (vesicular glutamate transporter), member 7	excitatory synapse	Cellular component	-
SEC24D	9871	SEC24 family member D	intracellular protein transport	Biological process	-
CLTB	1212	clathrin, light chain B	cytoplasm	Cellular component	-
ANXA7	310	annexin A7	nuclear envelope	Cellular component	-
CEPT1	10390	choline/ethanolamine phosphotransferase 1	CDP-choline pathway	Biological process	-
AURKA	6790	aurora kinase A	spindle stabilization	Biological process	21820309
TMEM173	340061	transmembrane protein 173	innate immune response	Biological process	-
ITGAM	3684	integrin, alpha M (complement component 3 receptor 3 subunit)	heparin binding	Molecular function	-
STAR	6770	steroidogenic acute regulatory protein	response to corticosterone	Biological process	-
RBSN	64145	rabenosyn, RAB effector	extracellular exosome	Cellular component	18570454
LRP2	4036	low density lipoprotein receptor-related protein 2	endosome	Cellular component	-
C5	727	complement component 5	complement activation, alternative pathway	Biological process	-
OR52R1	119695	olfactory receptor, family 52, subfamily R, member 1 (gene/pseudogene)	G-protein coupled receptor signaling pathway	Biological process	-
MAFG	4097	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G	regulation of cellular pH	Biological process	-
TLR3	7098	toll-like receptor 3	response to exogenous dsRNA	Biological process	21266579
RAP2C	57826	RAP2C, member of RAS oncogene family	negative regulation of cell migration	Biological process	-
C1D	10438	C1D nuclear receptor corepressor	ligand-dependent nuclear receptor binding	Molecular function	-
SRSF7	6432	serine/arginine-rich splicing factor 7	poly(A) RNA binding	Molecular function	22658674
ARNT	405	aryl hydrocarbon receptor nuclear translocator	positive regulation of glycolytic process	Biological process	8089148
GGCX	2677	gamma-glutamyl carboxylase	cellular protein modification process	Biological process	1749935
KLK4	9622	kallikrein-related peptidase 4	serine-type endopeptidase activity	Molecular function	-
B3GNT6	192134	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6	integral component of membrane	Cellular component	-
IL16	3603	interleukin 16	extracellular space	Cellular component	-
ICAM1	3383	intercellular adhesion molecule 1	focal adhesion	Cellular component	21423176
MKLN1	4289	muskelin 1, intracellular mediator containing kelch motifs	regulation of cell shape	Biological process	-
LDHD	197257	lactate dehydrogenase D	mitochondrion	Cellular component	-
EMX1	2016	empty spiracles homeobox 1	in utero embryonic development	Biological process	-
SPANXB1	728695	SPANX family, member B1	nucleus	Cellular component	10906052
CT45A5	441521	cancer/testis antigen family 45, member A5	protein binding	Molecular function	21516116
NIPBL	25836	Nipped-B homolog (Drosophila)	outflow tract morphogenesis	Biological process	19242925
RACGAP1	29127	Rac GTPase activating protein 1	cytosol	Cellular component	-
APLP2	334	amyloid beta (A4) precursor-like protein 2	midbrain development	Biological process	-
DEDD2	162989	death effector domain containing 2	protein binding	Molecular function	11741985
MAP3K19	80122	mitogen-activated protein kinase kinase kinase 19	activation of MAPKK activity	Biological process	-
GRIN3B	116444	glutamate receptor, ionotropic, N-methyl-D-aspartate 3B	regulation of calcium ion transport	Biological process	11735224
ALG11	440138	ALG11, alpha-1,2-mannosyltransferase	membrane	Cellular component	19946888
GPC4	2239	glypican 4	proteinaceous extracellular matrix	Cellular component	-
LIN7A	8825	lin-7 homolog A (C. elegans)	basolateral plasma membrane	Cellular component	-
HSD3B1	3283	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1	glucocorticoid biosynthetic process	Biological process	-
GUCA2B	2981	guanylate cyclase activator 2B (uroguanylin)	calcium sensitive guanylate cyclase activator activity	Molecular function	8605041
ZNF703	80139	zinc finger protein 703	positive regulation of cell proliferation	Biological process	21328542
PDCD4	27250	programmed cell death 4 (neoplastic transformation inhibitor)	cell aging	Biological process	12054647
INSM1	3642	insulinoma-associated 1	sequence-specific DNA binding transcription factor activity	Molecular function	11842116
FOLH1	2346	folate hydrolase (prostate-specific membrane antigen) 1	carboxypeptidase activity	Molecular function	-
PHB	5245	prohibitin	DNA biosynthetic process	Biological process	-
CYP1A1	1543	cytochrome P450, family 1, subfamily A, polypeptide 1	coumarin metabolic process	Biological process	-
CLEC12A	160364	C-type lectin domain family 12, member A	carbohydrate binding	Molecular function	-
FAM200A	221786	family with sequence similarity 200, member A	integral component of membrane	Cellular component	-
SCAND1	51282	SCAN domain containing 1	regulation of transcription from RNA polymerase II promoter	Biological process	-
UBE2A	7319	ubiquitin-conjugating enzyme E2A	protein polyubiquitination	Biological process	-
PSPHP1	8781	phosphoserine phosphatase pseudogene 1	dephosphorylation	Biological process	9573387
PLEK	5341	pleckstrin	cytoplasm	Cellular component	8694752
COL7A1	1294	collagen, type VII, alpha 1	extracellular matrix	Cellular component	22261194
RAB11A	8766	RAB11A, member RAS oncogene family	renal water homeostasis	Biological process	-
SRSF7	6432	serine/arginine-rich splicing factor 7	nucleoplasm	Cellular component	-
CBX5	23468	chromobox homolog 5	blood coagulation	Biological process	-
ACADVL	37	acyl-CoA dehydrogenase, very long chain	mitochondrial nucleoid	Cellular component	18063578
CTHRC1	115908	collagen triple helix repeat containing 1	collagen trimer	Cellular component	-
DFFB	1677	DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)	apoptotic DNA fragmentation	Biological process	-
LPIN1	23175	lipin 1	phosphatidylethanolamine biosynthetic process	Biological process	-
SPINK13	153218	serine peptidase inhibitor, Kazal type 13 (putative)	negative regulation of acrosome reaction	Biological process	-
APOE	348	apolipoprotein E	response to insulin	Biological process	-
MYF6	4618	myogenic factor 6 (herculin)	positive regulation of myoblast differentiation	Biological process	-
MTRR	4552	5-methyltetrahydrofolate-homocysteine methyltransferase reductase	DNA methylation	Biological process	-
CA3	761	carbonic anhydrase III	response to ethanol	Biological process	-
LIG3	3980	ligase III, DNA, ATP-dependent	negative regulation of mitochondrial DNA replication	Biological process	21878356
NEUROD6	63974	neuronal differentiation 6	protein dimerization activity	Molecular function	-
ZNF749	388567	zinc finger protein 749	metal ion binding	Molecular function	-
RFWD2	64326	ring finger and WD repeat domain 2, E3 ubiquitin protein ligase	Golgi membrane	Cellular component	-
SEMA3D	223117	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D	cell differentiation	Biological process	-
MLST8	64223	MTOR associated protein, LST8 homolog (S. cerevisiae)	vascular endothelial growth factor receptor signaling pathway	Biological process	-
FGFR2	2263	fibroblast growth factor receptor 2	positive regulation of phospholipase activity	Biological process	16844695
HNRNPH3	3189	heterogeneous nuclear ribonucleoprotein H3 (2H9)	protein binding	Molecular function	22720776
SPN	6693	sialophorin	response to protozoan	Biological process	-
ATP13A4	84239	ATPase type 13A4	integral component of membrane	Cellular component	-
RRAGC	64121	Ras-related GTP binding C	cell growth	Biological process	11073942
TP63	8626	tumor protein p63	epidermal cell division	Biological process	-
NPHP4	261734	nephronophthisis 4	photoreceptor cell maintenance	Biological process	-
ZNF836	162962	zinc finger protein 836	nucleus	Cellular component	-
BMPR2	659	bone morphogenetic protein receptor, type II (serine/threonine kinase)	dendrite	Cellular component	-
LEFTY1	10637	left-right determination factor 1	heart morphogenesis	Biological process	-
CSTF3	1479	cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa	mRNA cleavage	Biological process	7984242
AVP	551	arginine vasopressin	positive regulation of cAMP biosynthetic process	Biological process	-
AP2A1	160	adaptor-related protein complex 2, alpha 1 subunit	endocytosis	Biological process	12036598
FNTA	2339	farnesyltransferase, CAAX box, alpha	acetylcholine receptor regulator activity	Molecular function	-
FLT3	2322	fms-related tyrosine kinase 3	transmembrane receptor protein tyrosine kinase signaling pathway	Biological process	7507245
DDX3X	1654	DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	18846110
SERPINA5	5104	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5	phosphatidylcholine binding	Molecular function	9556620
HILS1	373861	histone linker H1 domain, spermatid-specific 1, pseudogene	nucleosome assembly	Biological process	-
MBD6	114785	methyl-CpG binding domain protein 6	chromatin binding	Molecular function	20700456
SH3KBP1	30011	SH3-domain kinase binding protein 1	endocytosis	Biological process	-
MYBBP1A	10514	MYB binding protein (P160) 1a	regulation of transcription, DNA-templated	Biological process	10644447
NPY5R	4889	neuropeptide Y receptor Y5	eating behavior	Biological process	-
CLIP1	6249	CAP-GLY domain containing linker protein 1	microtubule bundle formation	Biological process	17889670
HEBP2	23593	heme binding protein 2	protein binding	Molecular function	16189514
CTSL	1514	cathepsin L	proteolysis involved in cellular protein catabolic process	Biological process	22952693
MFSD8	256471	major facilitator superfamily domain containing 8	lysosome organization	Biological process	-
NOX4	50507	NADPH oxidase 4	cardiac muscle cell differentiation	Biological process	-
PFKFB2	5208	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2	fructose metabolic process	Biological process	-
MARK1	4139	MAP/microtubule affinity-regulating kinase 1	magnesium ion binding	Molecular function	14976552
EIF5A2	56648	eukaryotic translation initiation factor 5A2	peptidyl-lysine modification to peptidyl-hypusine	Biological process	-
THEM4	117145	thioesterase superfamily member 4	mitochondrion	Cellular component	19604401
HFE2	148738	hemochromatosis type 2 (juvenile)	protein binding	Molecular function	19357398
SLC35A5	55032	solute carrier family 35, member A5	nucleotide transmembrane transport	Biological process	-
BAZ2A	11176	bromodomain adjacent to zinc finger domain, 2A	RNA binding	Molecular function	-
MRPS11	64963	mitochondrial ribosomal protein S11	mitochondrial small ribosomal subunit	Cellular component	-
CLCA3P	9629	chloride channel accessory 3, pseudogene	chloride channel activity	Molecular function	-
PCNA	5111	proliferating cell nuclear antigen	DNA strand elongation involved in DNA replication	Biological process	-
PXMP4	11264	peroxisomal membrane protein 4, 24kDa	peroxisome	Cellular component	-
KMO	8564	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	NAD(P)H oxidase activity	Molecular function	10672018
CFL1	1072	cofilin 1 (non-muscle)	neural crest cell migration	Biological process	-
CDC20	991	cell division cycle 20	mitotic spindle assembly checkpoint	Biological process	-
FURIN	5045	furin (paired basic amino acid cleaving enzyme)	post-translational protein modification	Biological process	-
PRKCG	5582	protein kinase C, gamma	regulation of response to food	Biological process	-
GJA1	2697	gap junction protein, alpha 1, 43kDa	transport	Biological process	1696265
NUCB1	4924	nucleobindin 1	microtubule cytoskeleton	Cellular component	-
PF4	5196	platelet factor 4	positive regulation of gene expression	Biological process	10666185
CSRNP1	64651	cysteine-serine-rich nuclear protein 1	sequence-specific DNA binding transcription factor activity	Molecular function	17726538
DAB2	1601	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)	integrin-mediated signaling pathway	Biological process	19581412
GALNT1	2589	polypeptide N-acetylgalactosaminyltransferase 1	cellular protein metabolic process	Biological process	-
GABRA6	2559	gamma-aminobutyric acid (GABA) A receptor, alpha 6	ion transmembrane transport	Biological process	-
PLN	5350	phospholamban	membrane	Cellular component	19708671
CAV1	857	caveolin 1, caveolae protein, 22kDa	regulation of blood coagulation	Biological process	17848177
AIF1	199	allograft inflammatory factor 1	nucleus	Cellular component	-
SH2D3C	10044	SH2 domain containing 3C	protein binding	Molecular function	24728074
TET1	80312	tet methylcytosine dioxygenase 1	iron ion binding	Molecular function	19372391
RNMT	8731	RNA (guanine-7-) methyltransferase	viral process	Biological process	-
MOV10L1	54456	Mov10 RISC complex RNA helicase like 1	magnesium ion binding	Molecular function	11839499
MVD	4597	mevalonate (diphospho) decarboxylase	small molecule metabolic process	Biological process	-
ASIC1	41	acid sensing (proton gated) ion channel 1	associative learning	Biological process	-
OTC	5009	ornithine carbamoyltransferase	citrulline biosynthetic process	Biological process	2556444
GDPD4	220032	glycerophosphodiester phosphodiesterase domain containing 4	integral component of membrane	Cellular component	-
KIFAP3	22920	kinesin-associated protein 3	protein localization	Biological process	-
BAD	572	BCL2-associated agonist of cell death	suppression by virus of host apoptotic process	Biological process	-
CD55	1604	CD55 molecule, decay accelerating factor for complement (Cromer blood group)	lipid binding	Molecular function	12731067
HSP90AB1	3326	heat shock protein 90kDa alpha (cytosolic), class B member 1	nitric-oxide synthase regulator activity	Molecular function	-
WDR83	84292	WD repeat domain 83	spliceosomal complex	Cellular component	11991638
SLC34A1	6569	solute carrier family 34 (type II sodium/phosphate cotransporter), member 1	ossification	Biological process	-
CDK20	23552	cyclin-dependent kinase 20	cytoplasm	Cellular component	-
WT1	7490	Wilms tumor 1	sequence-specific DNA binding transcription factor activity	Molecular function	7862533
TACR1	6869	tachykinin receptor 1	positive regulation of vascular permeability	Biological process	-
NOC2L	26155	nucleolar complex associated 2 homolog (S. cerevisiae)	histone binding	Molecular function	16322561
NMI	9111	N-myc (and STAT) interactor	protein binding	Molecular function	10597290
ORC4	5000	origin recognition complex, subunit 4	cytoplasm	Cellular component	-
RNF5	6048	ring finger protein 5, E3 ubiquitin protein ligase	ubiquitin-protein transferase activity	Molecular function	19269966
LAMC2	3918	laminin, gamma 2	heparin binding	Molecular function	-
HEYL	26508	hes-related family bHLH transcription factor with YRPW motif-like	atrioventricular valve morphogenesis	Biological process	-
LIN7B	64130	lin-7 homolog B (C. elegans)	asymmetric protein localization	Biological process	-
CRKL	1399	v-crk avian sarcoma virus CT10 oncogene homolog-like	organ morphogenesis	Biological process	-
MBL2	4153	mannose-binding lectin (protein C) 2, soluble	opsonization	Biological process	2477488
ATXN3L	92552	ataxin 3-like	mitochondrial membrane	Cellular component	-
AAAS	8086	achalasia, adrenocortical insufficiency, alacrimia	regulation of cellular response to heat	Biological process	-
MAP2K2	5605	mitogen-activated protein kinase kinase 2	protein serine/threonine/tyrosine kinase activity	Molecular function	19565474
SPIRE2	84501	spire-type actin nucleation factor 2	formin-nucleated actin cable assembly	Biological process	-
RICTOR	253260	RPTOR independent companion of MTOR, complex 2	positive regulation of actin filament polymerization	Biological process	-
RNF217	154214	ring finger protein 217	integral component of membrane	Cellular component	-
ACTB	60	actin, beta	RNA polymerase II distal enhancer sequence-specific DNA binding	Molecular function	16217013
CTSZ	1522	cathepsin Z	angiotensin maturation	Biological process	-
DCP2	167227	decapping mRNA 2	histone mRNA catabolic process	Biological process	18172165
TUBG2	27175	tubulin, gamma 2	microtubule nucleation	Biological process	-
TRDN	10345	triadin	protein binding, bridging	Molecular function	-
ITSN1	6453	intersectin 1 (SH3 domain protein)	proline-rich region binding	Molecular function	20946875
OR4S2	219431	olfactory receptor, family 4, subfamily S, member 2	G-protein coupled receptor signaling pathway	Biological process	-
TWF2	11344	twinfilin actin-binding protein 2	positive regulation of axon extension	Biological process	17910947
FMR1	2332	fragile X mental retardation 1	microtubule	Cellular component	-
PHF10	55274	PHD finger protein 10	npBAF complex	Cellular component	-
LMX1A	4009	LIM homeobox transcription factor 1, alpha	zinc ion binding	Molecular function	-
OXA1L	5018	oxidase (cytochrome c) assembly 1-like	negative regulation of ATPase activity	Biological process	17936786
EDEM3	80267	ER degradation enhancer, mannosidase alpha-like 3	response to unfolded protein	Biological process	-
AQP11	282679	aquaporin 11	proximal tubule development	Biological process	-
IRF6	3664	interferon regulatory factor 6	keratinocyte proliferation	Biological process	-
ELF3	1999	E74-like factor 3 (ets domain transcription factor, epithelial-specific )	blastocyst development	Biological process	-
TH	7054	tyrosine hydroxylase	cellular response to glucose stimulus	Biological process	-
SOX17	64321	SRY (sex determining region Y)-box 17	positive regulation of transcription, DNA-templated	Biological process	-
NCK2	8440	NCK adaptor protein 2	endoplasmic reticulum	Cellular component	16835242
RAB11FIP4	84440	RAB11 family interacting protein 4 (class II)	midbody	Cellular component	15601896
TMEM253	643382	transmembrane protein 253	integral component of membrane	Cellular component	-
SEC24B	10427	SEC24 family member B	zinc ion binding	Molecular function	-
BNIP1	662	BCL2/adenovirus E1B 19kDa interacting protein 1	mitochondrion	Cellular component	-
PTPN6	5777	protein tyrosine phosphatase, non-receptor type 6	SH3 domain binding	Molecular function	-
PDE11A	50940	phosphodiesterase 11A	perikaryon	Cellular component	-
MED1	5469	mediator complex subunit 1	erythrocyte development	Biological process	-
SLC22A12	116085	solute carrier family 22 (organic anion/urate transporter), member 12	plasma membrane	Cellular component	-
ZBTB18	10472	zinc finger and BTB domain containing 18	in utero embryonic development	Biological process	-
IRF7	3665	interferon regulatory factor 7	regulation of MyD88-dependent toll-like receptor signaling pathway	Biological process	-
RBPJ	3516	recombination signal binding protein for immunoglobulin kappa J region	endocardium morphogenesis	Biological process	-
PRDX5	25824	peroxiredoxin 5	intracellular membrane-bounded organelle	Cellular component	15785239
PAEP	5047	progestagen-associated endometrial protein	extracellular region	Cellular component	-
SLC6A1	6529	solute carrier family 6 (neurotransmitter transporter), member 1	synaptic transmission	Biological process	-
VTI1A	143187	vesicle transport through interaction with t-SNAREs 1A	SNARE complex	Cellular component	15215310
ALAS1	211	5'-aminolevulinate synthase 1	porphyrin-containing compound metabolic process	Biological process	-
TRPM7	54822	transient receptor potential cation channel, subfamily M, member 7	calcium-dependent cell-matrix adhesion	Biological process	-
ATP5D	513	ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)	Cellular component	12539966
CYB5A	1528	cytochrome b5 type A (microsomal)	hydrogen ion transmembrane transport	Biological process	1712589
CYP2B6	1555	cytochrome P450, family 2, subfamily B, polypeptide 6	oxidation-reduction process	Biological process	19651758
CYP46A1	10858	cytochrome P450, family 46, subfamily A, polypeptide 1	endoplasmic reticulum	Cellular component	10377398
RRP8	23378	ribosomal RNA processing 8, methyltransferase, homolog (yeast)	negative regulation of gene expression, epigenetic	Biological process	-
DLG4	1742	discs, large homolog 4 (Drosophila)	guanylate kinase activity	Molecular function	-
PHIP	55023	pleckstrin homology domain interacting protein	regulation of protein phosphorylation	Biological process	-
ZNF865	100507290	zinc finger protein 865	DNA binding	Molecular function	-
CHRNG	1146	cholinergic receptor, nicotinic, gamma (muscle)	acetylcholine-gated channel complex	Cellular component	-
SNX11	29916	sorting nexin 11	endosome	Cellular component	23615901
SLIT2	9353	slit homolog 2 (Drosophila)	negative regulation of endothelial cell migration	Biological process	18345009
RASGEF1A	221002	RasGEF domain family, member 1A	Ras guanyl-nucleotide exchange factor activity	Molecular function	17121879
ENG	2022	endoglin	response to hypoxia	Biological process	18156205
BARHL2	343472	BarH-like homeobox 2	transcription, DNA-templated	Biological process	-
NDUFA11	126328	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa	cellular metabolic process	Biological process	-
USP9X	8239	ubiquitin specific peptidase 9, X-linked	protein deubiquitination	Biological process	19135894
HOMER1	9456	homer scaffolding protein 1	neuronal cell body	Cellular component	-
RB1	5925	retinoblastoma 1	striated muscle cell differentiation	Biological process	-
ZSCAN31	64288	zinc finger and SCAN domain containing 31	sequence-specific DNA binding transcription factor activity	Molecular function	-
ERVK-26	103539957	endogenous retrovirus group K, member 26	nucleolus	Cellular component	-
DSEL	92126	dermatan sulfate epimerase-like	carbohydrate metabolic process	Biological process	-
COL22A1	169044	collagen, type XXII, alpha 1	collagen trimer	Cellular component	-
MSI1	4440	musashi RNA-binding protein 1	RNA binding	Molecular function	9790759
SHROOM3	57619	shroom family member 3	neural tube closure	Biological process	-
NOTCH1	4851	notch 1	positive regulation of transcription, DNA-templated	Biological process	-
SH2D5	400745	SH2 domain containing 5	postsynaptic density	Cellular component	-
ZNF212	7988	zinc finger protein 212	transcription, DNA-templated	Biological process	-
PFKFB2	5208	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2	positive regulation of insulin secretion	Biological process	-
ANKLE2	23141	ankyrin repeat and LEM domain containing 2	integral component of endoplasmic reticulum membrane	Cellular component	22770216
TLR9	54106	toll-like receptor 9	positive regulation of interferon-beta production	Biological process	-
AAAS	8086	achalasia, adrenocortical insufficiency, alacrimia	hexose transport	Biological process	-
FZD2	2535	frizzled class receptor 2	positive regulation of sequence-specific DNA binding transcription factor activity	Biological process	18929644
CNST	163882	consortin, connexin sorting protein	plasma membrane	Cellular component	19864490
TNFSF8	944	tumor necrosis factor (ligand) superfamily, member 8	signal transduction	Biological process	8391931
OBSL1	23363	obscurin-like 1	cytoplasm	Cellular component	24793695
ADAM12	8038	ADAM metallopeptidase domain 12	cell adhesion	Biological process	-
TNFAIP1	7126	tumor necrosis factor, alpha-induced protein 1 (endothelial)	cell migration	Biological process	19782033
BNIPL	149428	BCL2/adenovirus E1B 19kD interacting protein like	nucleus	Cellular component	11741952
SPIDR	23514	scaffolding protein involved in DNA repair	protein binding	Molecular function	23509288
NOC3L	64318	nucleolar complex associated 3 homolog (S. cerevisiae)	chromatin binding	Molecular function	-
PRMT7	54496	protein arginine methyltransferase 7	[myelin basic protein]-arginine N-methyltransferase activity	Molecular function	15494416
PDLIM5	10611	PDZ and LIM domain 5	regulation of synapse assembly	Biological process	-
EDA	1896	ectodysplasin A	gene expression	Biological process	-
KCNN2	3781	potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2	potassium ion transmembrane transport	Biological process	17110593
LOC400927-CSNK1E	102800317	LOC400927-CSNK1E readthrough	cytosol	Cellular component	-
TFDP2	7029	transcription factor Dp-2 (E2F dimerization partner 2)	regulation of transcription from RNA polymerase II promoter	Biological process	-
UQCC2	84300	ubiquinol-cytochrome c reductase complex assembly factor 2	mitochondrial inner membrane	Cellular component	-
YBX1	4904	Y box binding protein 1	CRD-mediated mRNA stability complex	Cellular component	19029303
INPP5K	51763	inositol polyphosphate-5-phosphatase K	negative regulation of calcium ion transport	Biological process	12556481
ARV1	64801	ARV1 homolog (S. cerevisiae)	Golgi apparatus	Cellular component	-
SLC25A4	291	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4	mitochondrial inner membrane	Cellular component	-
CYFIP1	23191	cytoplasmic FMR1 interacting protein 1	small GTPase mediated signal transduction	Biological process	-
PUM2	23369	pumilio RNA-binding family member 2	stress granule assembly	Biological process	-
FAM175A	84142	family with sequence similarity 175, member A	nucleus	Cellular component	-
GLA	2717	galactosidase, alpha	sphingolipid metabolic process	Biological process	-
COL17A1	1308	collagen, type XVII, alpha 1	extracellular matrix disassembly	Biological process	-
PDK4	5166	pyruvate dehydrogenase kinase, isozyme 4	response to starvation	Biological process	-
UCK2	7371	uridine-cytidine kinase 2	pyrimidine nucleoside salvage	Biological process	-
CXADR	1525	coxsackie virus and adenovirus receptor	apicolateral plasma membrane	Cellular component	15364909
SLC25A13	10165	solute carrier family 25 (aspartate/glutamate carrier), member 13	integral component of plasma membrane	Cellular component	10642534
NSF	4905	N-ethylmaleimide-sensitive factor	ATPase activity, coupled	Molecular function	-
TEX35	84066	testis expressed 35	microtubule cytoskeleton	Cellular component	-
ADRA1B	147	adrenoceptor alpha 1B	protein heterodimerization activity	Molecular function	22120526
UMOD	7369	uromodulin	extrinsic component of membrane	Cellular component	7873609
KLF15	28999	Kruppel-like factor 15	transcription, DNA-templated	Biological process	-
DGKI	9162	diacylglycerol kinase, iota	cytoplasm	Cellular component	9830018
NPEPPS	9520	aminopeptidase puromycin sensitive	cellular response to hypoxia	Biological process	21056661
ZNF534	147658	zinc finger protein 534	nucleus	Cellular component	-
CALM2	805	calmodulin 2 (phosphorylase kinase, delta)	positive regulation of protein autophosphorylation	Biological process	20668654
S1PR3	1903	sphingosine-1-phosphate receptor 3	inflammatory response	Biological process	-
TFIP11	24144	tuftelin interacting protein 11	proteinaceous extracellular matrix	Cellular component	-
ITPR2	3709	inositol 1,4,5-trisphosphate receptor, type 2	epidermal growth factor receptor signaling pathway	Biological process	-
SLC4A9	83697	solute carrier family 4, sodium bicarbonate cotransporter, member 9	plasma membrane	Cellular component	-
PIP5K1A	8394	phosphatidylinositol-4-phosphate 5-kinase, type I, alpha	nucleus	Cellular component	15157668
APOA2	336	apolipoprotein A-II	protein homodimerization activity	Molecular function	17264082
ADA	100	adenosine deaminase	xanthine biosynthetic process	Biological process	-
TNFRSF21	27242	tumor necrosis factor receptor superfamily, member 21	negative regulation of interleukin-10 secretion	Biological process	-
SSB	6741	Sjogren syndrome antigen B (autoantigen La)	protein binding	Molecular function	23552417
SLC9C1	285335	solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1	ion transmembrane transport	Biological process	-
Sep-12	124404	septin 12	microtubule cytoskeleton	Cellular component	-
PSEN2	5664	presenilin 2	growth cone	Cellular component	-
OR2D2	120776	olfactory receptor, family 2, subfamily D, member 2	olfactory receptor activity	Molecular function	9787077
PIK3CD	5293	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	mast cell differentiation	Biological process	20940048
EXOSC6	118460	exosome component 6	nuclear exosome (RNase complex)	Cellular component	-
DENND4A	10260	DENN/MADD domain containing 4A	Rab guanyl-nucleotide exchange factor activity	Molecular function	20937701
KEL	3792	Kell blood group, metallo-endopeptidase	negative regulation of potassium ion transmembrane transport	Biological process	-
FGA	2243	fibrinogen alpha chain	plasma membrane	Cellular component	-
NDUFS4	4724	NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)	mitochondrial respiratory chain complex I assembly	Biological process	11112787
DNMT3B	1789	DNA (cytosine-5-)-methyltransferase 3 beta	regulation of gene expression by genetic imprinting	Biological process	-
C8orf49	606553	chromosome 8 open reading frame 49	integral component of membrane	Cellular component	-
APOB	338	apolipoprotein B	leukocyte migration	Biological process	-
PGLYRP4	57115	peptidoglycan recognition protein 4	N-acetylmuramoyl-L-alanine amidase activity	Molecular function	-
SPN	6693	sialophorin	negative regulation of type IV hypersensitivity	Biological process	-
TGFB1I1	7041	transforming growth factor beta 1 induced transcript 1	positive regulation of epithelial to mesenchymal transition	Biological process	18762808
ARHGEF10	9639	Rho guanine nucleotide exchange factor (GEF) 10	Rho guanyl-nucleotide exchange factor activity	Molecular function	16896804
SLC18A3	6572	solute carrier family 18 (vesicular acetylcholine transporter), member 3	ammonium transmembrane transport	Biological process	8071310
NPHS1	4868	nephrosis 1, congenital, Finnish type (nephrin)	protein domain specific binding	Molecular function	-
AGXT	189	alanine-glyoxylate aminotransferase	response to glucocorticoid	Biological process	-
CXCR3	2833	chemokine (C-X-C motif) receptor 3	positive regulation of release of sequestered calcium ion into cytosol	Biological process	12782716
SLC8A2	6543	solute carrier family 8 (sodium/calcium exchanger), member 2	integral component of membrane	Cellular component	-
CRX	1406	cone-rod homeobox	retina development in camera-type eye	Biological process	-
STEAP3	55240	STEAP family member 3, metalloreductase	ferric-chelate reductase activity	Molecular function	-
PPM1F	9647	protein phosphatase, Mg2+/Mn2+ dependent, 1F	intrinsic apoptotic signaling pathway	Biological process	11559703
ARFIP2	23647	ADP-ribosylation factor interacting protein 2	trans-Golgi network membrane	Cellular component	23695357
ATP12A	479	ATPase, H+/K+ transporting, nongastric, alpha polypeptide	basolateral plasma membrane	Cellular component	-
PRPF40A	55660	PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)	cell division	Biological process	-
DDX41	51428	DEAD (Asp-Glu-Ala-Asp) box polypeptide 41	membrane	Cellular component	19946888
EID3	493861	EP300 interacting inhibitor of differentiation 3	post-translational protein modification	Biological process	-
EXOSC8	11340	exosome component 8	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	Biological process	-
DYRK1B	9149	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B	protein kinase activity	Molecular function	11980910
ITIH2	3698	inter-alpha-trypsin inhibitor heavy chain 2	extracellular region	Cellular component	14718574
CTBP1	1487	C-terminal binding protein 1	transcription factor binding	Molecular function	16609867
PRKAR1A	5573	protein kinase, cAMP-dependent, regulatory, type I, alpha	small molecule metabolic process	Biological process	-
CYP8B1	1582	cytochrome P450, family 8, subfamily B, polypeptide 1	integral component of membrane	Cellular component	-
PRKAA1	5562	protein kinase, AMP-activated, alpha 1 catalytic subunit	protein binding	Molecular function	16306228
PYCARD	29108	PYD and CARD domain containing	regulation of intrinsic apoptotic signaling pathway	Biological process	14730312
EPS8	2059	epidermal growth factor receptor pathway substrate 8	Rac GTPase binding	Molecular function	-
YWHAH	7533	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta	glucocorticoid receptor binding	Molecular function	9079630
ALAS1	211	5'-aminolevulinate synthase 1	cytoplasm	Cellular component	-
F2	2147	coagulation factor II (thrombin)	peptidyl-glutamic acid carboxylation	Biological process	-
AP1G2	8906	adaptor-related protein complex 1, gamma 2 subunit	protein binding	Molecular function	12505986
FAM90A1	55138	family with sequence similarity 90, member A1	zinc ion binding	Molecular function	-
HAS2	3037	hyaluronan synthase 2	cellular response to tumor necrosis factor	Biological process	20522558
SSH2	85464	slingshot protein phosphatase 2	DNA binding	Molecular function	-
MLLT6	4302	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6	regulation of transcription, DNA-templated	Biological process	8058765
CLEC3B	7123	C-type lectin domain family 3, member B	cellular response to transforming growth factor beta stimulus	Biological process	7589422
VWA5A	4013	von Willebrand factor A domain containing 5A	nucleoplasm	Cellular component	-
RYR1	6261	ryanodine receptor 1 (skeletal)	junctional membrane complex	Cellular component	-
MED6	10001	mediator complex subunit 6	transcription coactivator activity	Molecular function	12037571
RPA2	6118	replication protein A2, 32kDa	DNA damage response, detection of DNA damage	Biological process	-
OTOG	340990	otogelin	extracellular space	Cellular component	-
TRBC2	28638	T cell receptor beta constant 2	integral component of membrane	Cellular component	-
TSG101	7251	tumor susceptibility 101	regulation of viral release from host cell	Biological process	11595185
CD274	29126	CD274 molecule	protein binding	Molecular function	21982860
NDUFC2-KCTD14	100532726	NDUFC2-KCTD14 readthrough	NADH dehydrogenase (ubiquinone) activity	Molecular function	-
LAT	27040	linker for activation of T cells	mast cell granule	Cellular component	-
DAB2	1601	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)	focal adhesion	Cellular component	21423176
DMD	1756	dystrophin	cardiac muscle cell action potential	Biological process	20080623
RSG1	79363	REM2 and RAB-like small GTPase 1	small GTPase mediated signal transduction	Biological process	-
RNF135	84282	ring finger protein 135	protein ubiquitination	Biological process	-
CNOT1	23019	CCR4-NOT transcription complex, subunit 1	extracellular space	Cellular component	22664934
PSMB10	5699	proteasome (prosome, macropain) subunit, beta type, 10	apoptotic process	Biological process	-
DLD	1738	dihydrolipoamide dehydrogenase	mitochondrial matrix	Cellular component	-
HS6ST3	266722	heparan sulfate 6-O-sulfotransferase 3	heparan sulfate proteoglycan biosynthetic process, enzymatic modification	Biological process	-
EIF3A	8661	eukaryotic translation initiation factor 3, subunit A	protein binding	Molecular function	11169732
GCK	2645	glucokinase (hexokinase 4)	glucose metabolic process	Biological process	-
TIPIN	54962	TIMELESS interacting protein	cell division	Biological process	-
PNPLA8	50640	patatin-like phospholipase domain containing 8	arachidonic acid metabolic process	Biological process	10833412
SLC31A1	1317	solute carrier family 31 (copper transporter), member 1	copper ion import into cell	Biological process	-
TCF12	6938	transcription factor 12	nucleus	Cellular component	-
IGF2BP2	10644	insulin-like growth factor 2 mRNA binding protein 2	mRNA 3'-UTR binding	Molecular function	20080952
GNG8	94235	guanine nucleotide binding protein (G protein), gamma 8	cellular response to glucagon stimulus	Biological process	-
RPS23	6228	ribosomal protein S23	cytosolic small ribosomal subunit	Cellular component	15883184
DOHH	83475	deoxyhypusine hydroxylase/monooxygenase	cytosol	Cellular component	-
IRGM	345611	immunity-related GTPase family, M	cell projection	Cellular component	-
TRIM62	55223	tripartite motif containing 62	positive regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	23077300
USP2	9099	ubiquitin specific peptidase 2	nucleus	Cellular component	-
SCAF4	57466	SR-related CTD-associated factor 4	nucleoplasm	Cellular component	-
TOB1	10140	transducer of ERBB2, 1	negative regulation of translation	Biological process	23236473
ABL1	25	ABL proto-oncogene 1, non-receptor tyrosine kinase	positive regulation of cytosolic calcium ion concentration	Biological process	24367707
ALDH1A3	220	aldehyde dehydrogenase 1 family, member A3	oxidation-reduction process	Biological process	-
RFC2	5982	replication factor C (activator 1) 2, 40kDa	transcription-coupled nucleotide-excision repair	Biological process	-
CERK	64781	ceramide kinase	small molecule metabolic process	Biological process	-
PSMC6	5706	proteasome (prosome, macropain) 26S subunit, ATPase, 6	regulation of cellular amino acid metabolic process	Biological process	-
SYT13	57586	synaptotagmin XIII	plasma membrane	Cellular component	-
HTR6	3362	5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled	response to drug	Biological process	-
COL3A1	1281	collagen, type III, alpha 1	digestive tract development	Biological process	-
BBS7	55212	Bardet-Biedl syndrome 7	nonmotile primary cilium assembly	Biological process	-
GOLPH3	64083	golgi phosphoprotein 3 (coat-protein)	Golgi apparatus	Cellular component	18410729
UCK2	7371	uridine-cytidine kinase 2	nucleoside kinase activity	Molecular function	-
NDUFAB1	4706	NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa	small molecule metabolic process	Biological process	-
OR2A7	401427	olfactory receptor, family 2, subfamily A, member 7	detection of chemical stimulus involved in sensory perception	Biological process	-
UAP1	6675	UDP-N-acetylglucosamine pyrophosphorylase 1	UDP-N-acetylglucosamine diphosphorylase activity	Molecular function	-
DBH	1621	dopamine beta-hydroxylase (dopamine beta-monooxygenase)	homoiothermy	Biological process	-
BAIAP3	8938	BAI1-associated protein 3	cell	Cellular component	9790924
CYBA	1535	cytochrome b-245, alpha polypeptide	cellular response to mechanical stimulus	Biological process	-
MYOD1	4654	myogenic differentiation 1	chromatin DNA binding	Molecular function	-
ZNF148	7707	zinc finger protein 148	gamete generation	Biological process	-
ABHD14B	84836	abhydrolase domain containing 14B	nucleus	Cellular component	-
SPHK1	8877	sphingosine kinase 1	positive regulation of neurotransmitter secretion	Biological process	-
FEN1	2237	flap structure-specific endonuclease 1	nucleolus	Cellular component	-
ZBED2	79413	zinc finger, BED-type containing 2	DNA binding	Molecular function	-
OR2AK2	391191	olfactory receptor, family 2, subfamily AK, member 2	G-protein coupled receptor signaling pathway	Biological process	-
TBL3	10607	transducin (beta)-like 3	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Biological process	-
LRRTM2	26045	leucine rich repeat transmembrane neuronal 2	neurexin family protein binding	Molecular function	-
IL1RN	3557	interleukin 1 receptor antagonist	response to interleukin-4	Biological process	-
ST14	6768	suppression of tumorigenicity 14 (colon carcinoma)	keratinocyte differentiation	Biological process	18843291
LSM10	84967	LSM10, U7 small nuclear RNA associated	nucleoplasm	Cellular component	-
FARS2	10667	phenylalanyl-tRNA synthetase 2, mitochondrial	cytoplasm	Cellular component	-
RPS6KA5	9252	ribosomal protein S6 kinase, 90kDa, polypeptide 5	intracellular signal transduction	Biological process	9687510
TRIM27	5987	tripartite motif containing 27	negative regulation of viral release from host cell	Biological process	-
CDC25B	994	cell division cycle 25B	positive regulation of protein kinase activity	Biological process	-
ITPK1	3705	inositol-tetrakisphosphate 1-kinase	magnesium ion binding	Molecular function	-
PAK3	5063	p21 protein (Cdc42/Rac)-activated kinase 3	innate immune response	Biological process	-
NOTCH3	4854	notch 3	positive regulation of smooth muscle cell proliferation	Biological process	-
OC90	729330	otoconin 90	biological_process	Biological process	-
PFKFB3	5209	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	dephosphorylation	Biological process	-
MED30	90390	mediator complex subunit 30	thyroid hormone receptor binding	Molecular function	10198638
CCS	9973	copper chaperone for superoxide dismutase	copper ion transmembrane transport	Biological process	9726962
PPP2R3A	5523	protein phosphatase 2, regulatory subunit B'', alpha	regulation of protein phosphatase type 2A activity	Biological process	8392071
EYA1	2138	EYA transcriptional coactivator and phosphatase 1	histone dephosphorylation	Biological process	19234442
CLDN5	7122	claudin 5	identical protein binding	Molecular function	-
SCX	642658	scleraxis basic helix-loop-helix transcription factor	heart valve formation	Biological process	-
GHSR	2693	growth hormone secretagogue receptor	peptide hormone binding	Molecular function	-
PRKCZ	5590	protein kinase C, zeta	positive regulation of ERK1 and ERK2 cascade	Biological process	11035106
CDK5	1020	cyclin-dependent kinase 5	cell cycle	Biological process	-
BMP4	652	bone morphogenetic protein 4	cranial suture morphogenesis	Biological process	-
BRS3	680	bombesin-like receptor 3	bombesin receptor activity	Molecular function	-
LDHB	3945	lactate dehydrogenase B	NAD binding	Molecular function	-
PTEN	5728	phosphatase and tensin homolog	protein tyrosine/serine/threonine phosphatase activity	Molecular function	-
CTDP1	9150	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1	positive regulation of viral transcription	Biological process	-
CHRNB4	1143	cholinergic receptor, nicotinic, beta 4 (neuronal)	synaptic transmission, cholinergic	Biological process	1330682
APBA1	320	amyloid beta (A4) precursor protein-binding, family A, member 1	gamma-aminobutyric acid secretion	Biological process	-
PCDHB3	56132	protocadherin beta 3	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	Biological process	11322959
CETN1	1068	centrin, EF-hand protein, 1	mitotic nuclear division	Biological process	-
TNFSF4	7292	tumor necrosis factor (ligand) superfamily, member 4	positive regulation of memory T cell differentiation	Biological process	-
MED4	29079	mediator complex subunit 4	transcription from RNA polymerase II promoter	Biological process	10882111
TGM3	7053	transglutaminase 3	keratinocyte differentiation	Biological process	24643
POLR2A	5430	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	DNA binding	Molecular function	7622068
ZNF225	7768	zinc finger protein 225	metal ion binding	Molecular function	-
ZNF880	400713	zinc finger protein 880	regulation of transcription, DNA-templated	Biological process	-
HIST1H1C	3006	histone cluster 1, H1c	poly(A) RNA binding	Molecular function	22658674
OTX2	5015	orthodenticle homeobox 2	protein heterodimerization activity	Molecular function	-
TSC2	7249	tuberous sclerosis 2	protein localization	Biological process	-
SNAP23	8773	synaptosomal-associated protein, 23kDa	vesicle targeting	Biological process	8663154
PSMC5	5705	proteasome (prosome, macropain) 26S subunit, ATPase, 5	negative regulation of programmed cell death	Biological process	16432160
CHEK2	11200	checkpoint kinase 2	nucleoplasm	Cellular component	-
POLA2	23649	polymerase (DNA directed), alpha 2, accessory subunit	DNA strand elongation involved in DNA replication	Biological process	-
ACOT8	10005	acyl-CoA thioesterase 8	viral process	Biological process	-
DLG4	1742	discs, large homolog 4 (Drosophila)	cortical cytoskeleton	Cellular component	12151521
SYTL4	94121	synaptotagmin-like 4	transport vesicle membrane	Cellular component	-
AVIL	10677	advillin	cilium morphogenesis	Biological process	20393563
DBT	1629	dihydrolipoamide branched chain transacylase E2	small molecule metabolic process	Biological process	-
PRKACG	5568	protein kinase, cAMP-dependent, catalytic, gamma	energy reserve metabolic process	Biological process	-
PTGDS	5730	prostaglandin D2 synthase 21kDa (brain)	prostaglandin-D synthase activity	Molecular function	-
CLU	1191	clusterin	mitochondrion	Cellular component	16113678
PRSS27	83886	protease, serine 27	extracellular region	Cellular component	-
GGT3P	2679	gamma-glutamyltransferase 3 pseudogene	glutathione hydrolase activity	Molecular function	-
VCAM1	7412	vascular cell adhesion molecule 1	cell adhesion	Biological process	16809613
MRLN	100507027	myoregulin	integral component of membrane	Cellular component	-
MED24	9862	mediator complex subunit 24	stem cell maintenance	Biological process	-
TNNC1	7134	troponin C type 1 (slow)	calcium ion binding	Molecular function	12840750
CALM2	805	calmodulin 2 (phosphorylase kinase, delta)	positive regulation of nitric-oxide synthase activity	Biological process	-
RPS29	6235	ribosomal protein S29	translational elongation	Biological process	-
ASB16	92591	ankyrin repeat and SOCS box containing 16	intracellular signal transduction	Biological process	-
ZNF354A	6940	zinc finger protein 354A	kidney development	Biological process	-
LHPP	64077	phospholysine phosphohistidine inorganic pyrophosphate phosphatase	protein dephosphorylation	Biological process	-
ZNF300	91975	zinc finger protein 300	regulation of transcription, DNA-templated	Biological process	-
KIF5A	3798	kinesin family member 5A	protein binding	Molecular function	22705394
PCSK2	5126	proprotein convertase subtilisin/kexin type 2	transport vesicle	Cellular component	-
TPRN	286262	taperin	stereocilium	Cellular component	-
DLL1	28514	delta-like 1 (Drosophila)	hemopoiesis	Biological process	11581320
IPO11	51194	importin 11	Ran GTPase binding	Molecular function	-
GNE	10020	glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase	cellular protein metabolic process	Biological process	-
UBB	7314	ubiquitin B	mitochondrion	Cellular component	17571083
COBL	23242	cordon-bleu WH2 repeat protein	ruffle	Cellular component	-
REV1	51455	REV1, polymerase (DNA directed)	damaged DNA binding	Molecular function	-
CDC14B	8555	cell division cycle 14B	activation of anaphase-promoting complex activity	Biological process	18662541
GRM6	2916	glutamate receptor, metabotropic 6	G-protein coupled glutamate receptor signaling pathway	Biological process	23452348
GRM4	2914	glutamate receptor, metabotropic 4	group III metabotropic glutamate receptor activity	Molecular function	-
DHRS4	10901	dehydrogenase/reductase (SDR family) member 4	protein tetramerization	Biological process	18571493
PSMB4	5692	proteasome (prosome, macropain) subunit, beta type, 4	programmed cell death	Biological process	-
CTPS1	1503	CTP synthase 1	glutamine metabolic process	Biological process	-
PCGF1	84759	polycomb group ring finger 1	regulation of transcription, DNA-templated	Biological process	-
RPS6KA5	9252	ribosomal protein S6 kinase, 90kDa, polypeptide 5	protein phosphorylation	Biological process	9687510
USP17L11	100287178	ubiquitin specific peptidase 17-like family member 11	endoplasmic reticulum	Cellular component	-
PPM1E	22843	protein phosphatase, Mg2+/Mn2+ dependent, 1E	protein serine/threonine phosphatase activity	Molecular function	20801214
ACR	49	acrosin	protein complex	Cellular component	7521127
FMNL1	752	formin-like 1	cell cortex	Cellular component	-
MKNK2	2872	MAP kinase interacting serine/threonine kinase 2	nucleoplasm	Cellular component	-
UHRF1	29128	ubiquitin-like with PHD and ring finger domains 1	cell cycle	Biological process	-
OSR2	116039	odd-skipped related transciption factor 2	mesonephros development	Biological process	-
CACNA1S	779	calcium channel, voltage-dependent, L type, alpha 1S subunit	axon guidance	Biological process	-
SNRNP27	11017	small nuclear ribonucleoprotein 27kDa (U4/U6.U5)	mRNA processing	Biological process	-
NKX2-5	1482	NK2 homeobox 5	spleen development	Biological process	8900537
COX7A2	1347	cytochrome c oxidase subunit VIIa polypeptide 2 (liver)	extracellular exosome	Cellular component	23376485
OR13F1	138805	olfactory receptor, family 13, subfamily F, member 1	adenylate cyclase-activating adrenergic receptor signaling pathway	Biological process	-
OR1G1	8390	olfactory receptor, family 1, subfamily G, member 1	detection of chemical stimulus involved in sensory perception	Biological process	-
ROR2	4920	receptor tyrosine kinase-like orphan receptor 2	positive regulation of transcription, DNA-templated	Biological process	-
SLC19A3	80704	solute carrier family 19 (thiamine transporter), member 3	integral component of membrane	Cellular component	11136550
COL7A1	1294	collagen, type VII, alpha 1	serine-type endopeptidase inhibitor activity	Molecular function	-
CCL14	6358	chemokine (C-C motif) ligand 14	cell chemotaxis	Biological process	-
YAP1	10413	Yes-associated protein 1	transcription corepressor activity	Molecular function	18158288
SPARC	6678	secreted protein, acidic, cysteine-rich (osteonectin)	platelet alpha granule lumen	Cellular component	-
PIK3C2A	5286	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha	phosphatidylinositol 3-kinase activity	Molecular function	17371240
SLC7A1	6541	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1	L-ornithine transmembrane transporter activity	Molecular function	-
ARL4D	379	ADP-ribosylation factor-like 4D	plasma membrane	Cellular component	17398095
PPIL2	23759	peptidylprolyl isomerase (cyclophilin)-like 2	leukocyte migration	Biological process	-
C1GALT1C1	29071	C1GALT1-specific chaperone 1	protein binding	Molecular function	21496458
DUSP10	11221	dual specificity phosphatase 10	nucleoplasm	Cellular component	-
MID1	4281	midline 1	microtubule cytoskeleton organization	Biological process	10077590
PPEF1	5475	protein phosphatase, EF-hand calcium binding domain 1	iron ion binding	Molecular function	-
BHLHA15	168620	basic helix-loop-helix family, member a15	cell maturation	Biological process	-
RGS6	9628	regulator of G-protein signaling 6	Golgi apparatus	Cellular component	-
NUP205	23165	nucleoporin 205kDa	viral life cycle	Biological process	-
SFRP2	6423	secreted frizzled-related protein 2	endopeptidase activator activity	Molecular function	-
CRISP3	10321	cysteine-rich secretory protein 3	extracellular region	Cellular component	12009203
HIST2H4B	554313	histone cluster 2, H4b	nucleus	Cellular component	14585971
SPAG16	79582	sperm associated antigen 16	motile cilium	Cellular component	-
HUWE1	10075	HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase	nucleoplasm	Cellular component	-
SRPX	8406	sushi-repeat containing protein, X-linked	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	Biological process	-
TSEN34	79042	TSEN34 tRNA splicing endonuclease subunit	nucleoplasm	Cellular component	-
ITGA4	3676	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	fibronectin binding	Molecular function	-
TSNARE1	203062	t-SNARE domain containing 1	endomembrane system	Cellular component	-
SEL1L	6400	sel-1 suppressor of lin-12-like (C. elegans)	integral component of membrane	Cellular component	-
FA2H	79152	fatty acid 2-hydroxylase	iron ion binding	Molecular function	-
TACC3	10460	transforming, acidic coiled-coil containing protein 3	astral microtubule organization	Biological process	-
SCRT2	85508	scratch family zinc finger 2	nuclear chromatin	Cellular component	-
SH3GLB1	51100	SH3-domain GRB2-like endophilin B1	receptor catabolic process	Biological process	20643123
EVL	51466	Enah/Vasp-like	positive regulation of actin filament polymerization	Biological process	-
TSPY10	100289087	testis specific protein, Y-linked 10	gonadal mesoderm development	Biological process	-
PLXNB3	5365	plexin B3	integral component of membrane	Cellular component	-
CWC22	57703	CWC22 spliceosome-associated protein	spliceosomal complex	Cellular component	11991638
TGFBI	7045	transforming growth factor, beta-induced, 68kDa	protein binding	Molecular function	19478074
GSTA1	2938	glutathione S-transferase alpha 1	glutathione transferase activity	Molecular function	1731620
RNF121	55298	ring finger protein 121	ER-associated ubiquitin-dependent protein catabolic process	Biological process	-
NKD2	85409	naked cuticle homolog 2 (Drosophila)	positive regulation of protein processing	Biological process	15064403
NPR3	4883	natriuretic peptide receptor 3	G-protein coupled peptide receptor activity	Molecular function	-
AIM2	9447	absent in melanoma 2	cytoplasm	Cellular component	19158676
SPATA32	124783	spermatogenesis associated 32	perinuclear region of cytoplasm	Cellular component	-
ALS2	57679	amyotrophic lateral sclerosis 2 (juvenile)	endosomal transport	Biological process	-
HIST2H2BF	440689	histone cluster 2, H2bf	nuclear nucleosome	Cellular component	-
NLRC4	58484	NLR family, CARD domain containing 4	interleukin-1 beta secretion	Biological process	15882992
PNN	5411	pinin, desmosome associated protein	mRNA splicing, via spliceosome	Biological process	11991638
ACAN	176	aggrecan	proteinaceous extracellular matrix	Cellular component	-
ANXA2	302	annexin A2	endosome	Cellular component	18767904
SSBP3	23648	single stranded DNA binding protein 3	nucleus	Cellular component	-
KHK	3795	ketohexokinase (fructokinase)	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate	Biological process	-
PPP1R3D	5509	protein phosphatase 1, regulatory subunit 3D	enzyme binding	Molecular function	-
DLAT	1737	dihydrolipoamide S-acetyltransferase	dihydrolipoyllysine-residue acetyltransferase activity	Molecular function	3191998
MAPK12	6300	mitogen-activated protein kinase 12	mitochondrion organization	Biological process	-
CD209	30835	CD209 molecule	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	Biological process	1518869
NXPH2	11249	neurexophilin 2	neuropeptide signaling pathway	Biological process	9570794
CEP250	11190	centrosomal protein 250kDa	cytosol	Cellular component	-
OR11H12	440153	olfactory receptor, family 11, subfamily H, member 12	olfactory receptor activity	Molecular function	-
BMP4	652	bone morphogenetic protein 4	chemoattractant activity	Molecular function	12631064
CHD7	55636	chromodomain helicase DNA binding protein 7	regulation of neurogenesis	Biological process	-
KANK1	23189	KN motif and ankyrin repeat domains 1	negative regulation of ruffle assembly	Biological process	19171758
DCTN2	10540	dynactin 2 (p50)	mitotic spindle organization	Biological process	-
AKAP8	10270	A kinase (PRKA) anchor protein 8	poly(A) RNA binding	Molecular function	22658674
HSPA8	3312	heat shock 70kDa protein 8	membrane	Cellular component	19946888
PDGFA	5154	platelet-derived growth factor alpha polypeptide	positive regulation of mesenchymal cell proliferation	Biological process	-
CDH2	1000	cadherin 2, type 1, N-cadherin (neuronal)	calcium ion binding	Molecular function	-
PCM1	5108	pericentriolar material 1	identical protein binding	Molecular function	-
NCBP2	22916	nuclear cap binding protein subunit 2, 20kDa	ncRNA metabolic process	Biological process	-
T	6862	T, brachyury homolog (mouse)	RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription	Molecular function	-
NBPF20	100288142	neuroblastoma breakpoint family, member 20	cytoplasm	Cellular component	-
SSTR2	6752	somatostatin receptor 2	cellular response to estradiol stimulus	Biological process	-
ACAA2	10449	acetyl-CoA acyltransferase 2	mitochondrial inner membrane	Cellular component	-
TOLLIP	54472	toll interacting protein	cytoplasm	Cellular component	11441107
FABP3	2170	fatty acid binding protein 3, muscle and heart	long-chain fatty acid transporter activity	Molecular function	-
OTX2	5015	orthodenticle homeobox 2	eye photoreceptor cell fate commitment	Biological process	-
FLOT2	2319	flotillin 2	protein heterodimerization activity	Molecular function	21696602
CNOT8	9337	CCR4-NOT transcription complex, subunit 8	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	Biological process	20065043
ADAP1	11033	ArfGAP with dual PH domains 1	regulation of GTPase activity	Biological process	10333475
HOPX	84525	HOP homeobox	nucleus	Cellular component	17192267
SYNGR2	9144	synaptogyrin 2	synaptic vesicle membrane	Cellular component	-
CX3CL1	6376	chemokine (C-X3-C motif) ligand 1	defense response	Biological process	12714508
IHH	3549	indian hedgehog	embryonic camera-type eye morphogenesis	Biological process	-
PSMA8	143471	proteasome (prosome, macropain) subunit, alpha type, 8	innate immune response	Biological process	-
SLC17A5	26503	solute carrier family 17 (acidic sugar transporter), member 5	integral component of plasma membrane	Cellular component	10581036
POLR2E	5434	polymerase (RNA) II (DNA directed) polypeptide E, 25kDa	viral process	Biological process	-
GCM1	8521	glial cells missing homolog 1 (Drosophila)	protein binding	Molecular function	23867755
TAL1	6886	T-cell acute lymphocytic leukemia 1	positive regulation of protein complex assembly	Biological process	20855495
ING4	51147	inhibitor of growth family, member 4	histone H4-K8 acetylation	Biological process	16387653
PARVB	29780	parvin, beta	cytoskeleton	Cellular component	-
DPPA3	359787	developmental pluripotency associated 3	embryonic cleavage	Biological process	-
PFKFB1	5207	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	fructose-6-phosphate binding	Molecular function	-
EZR	7430	ezrin	actin filament bundle assembly	Biological process	10793131
ZC3H8	84524	zinc finger CCCH-type containing 8	apoptotic process	Biological process	-
PRPF6	24148	pre-mRNA processing factor 6	RNA binding	Molecular function	20797886
SCNN1A	6337	sodium channel, non voltage gated 1 alpha subunit	protein binding	Molecular function	11244092
TLE1	7088	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	nucleoplasm	Cellular component	-
HLA-DRB4	3126	major histocompatibility complex, class II, DR beta 4	Golgi membrane	Cellular component	-
ITGB1	3688	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	positive regulation of cell migration	Biological process	-
TBP	6908	TATA box binding protein	positive regulation of transcription, DNA-templated	Biological process	-
ZNF814	730051	zinc finger protein 814	metal ion binding	Molecular function	-
XBP1	7494	X-box binding protein 1	cytoplasm	Cellular component	-
GSG2	83903	germ cell associated 2 (haspin)	intracellular signal transduction	Biological process	11228240
MRPS7	51081	mitochondrial ribosomal protein S7	translation	Biological process	-
CYP2A6	1548	cytochrome P450, family 2, subfamily A, polypeptide 6	coumarin metabolic process	Biological process	19651758
CNTN6	27255	contactin 6	anchored component of membrane	Cellular component	-
AWAT1	158833	acyl-CoA wax alcohol acyltransferase 1	integral component of membrane	Cellular component	-
BFAR	51283	bifunctional apoptosis regulator	ubiquitin protein ligase activity	Molecular function	21068390
INHBA	3624	inhibin, beta A	negative regulation of phosphorylation	Biological process	12456957
LIG4	3981	ligase IV, DNA, ATP-dependent	DNA ligase activity	Molecular function	-
MECP2	4204	methyl CpG binding protein 2	neuron maturation	Biological process	-
FKBP5	2289	FK506 binding protein 5	FK506 binding	Molecular function	9001212
DGKG	1608	diacylglycerol kinase, gamma 90kDa	ATP binding	Molecular function	-
PRB2	653247	proline-rich protein BstNI subfamily 2	biological_process	Biological process	-
ADAM32	203102	ADAM metallopeptidase domain 32	proteolysis	Biological process	-
IL1RAP	3556	interleukin 1 receptor accessory protein	inflammatory response	Biological process	-
PTGDR	5729	prostaglandin D2 receptor (DP)	inflammatory response	Biological process	-
SETD3	84193	SET domain containing 3	positive regulation of transcription, DNA-templated	Biological process	-
OVGP1	5016	oviductal glycoprotein 1, 120kDa	carbohydrate metabolic process	Biological process	-
CLN8	2055	ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)	visual perception	Biological process	-
BEST4	266675	bestrophin 4	chloride channel activity	Molecular function	-
SEL1L	6400	sel-1 suppressor of lin-12-like (C. elegans)	Notch signaling pathway	Biological process	-
NEUROG3	50674	neurogenin 3	positive regulation of transcription from RNA polymerase II promoter	Biological process	16511571
ZMYND11	10771	zinc finger, MYND-type containing 11	viral process	Biological process	-
SHANK3	85358	SH3 and multiple ankyrin repeat domains 3	positive regulation of dendritic spine development	Biological process	21795692
NUP35	129401	nucleoporin 35kDa	nucleoplasm	Cellular component	-
BBS1	582	Bardet-Biedl syndrome 1	protein localization to cilium	Biological process	23943788
STAP1	26228	signal transducing adaptor family member 1	negative regulation of macrophage chemotaxis	Biological process	-
ADAM8	101	ADAM metallopeptidase domain 8	positive regulation of protein kinase B signaling	Biological process	-
NTAN1	123803	N-terminal asparagine amidase	memory	Biological process	-
SORBS2	8470	sorbin and SH3 domain containing 2	perinuclear region of cytoplasm	Cellular component	-
RHOBTB2	23221	Rho-related BTB domain containing 2	GTP binding	Molecular function	-
CRLF1	9244	cytokine receptor-like factor 1	receptor activity	Molecular function	9686600
TAL2	6887	T-cell acute lymphocytic leukemia 2	midbrain development	Biological process	-
U2AF2	11338	U2 small nuclear RNA auxiliary factor 2	mRNA export from nucleus	Biological process	-
CXCL12	6387	chemokine (C-X-C motif) ligand 12	positive regulation of cell adhesion	Biological process	23620790
EPAS1	2034	endothelial PAS domain protein 1	surfactant homeostasis	Biological process	-
RORA	6095	RAR-related orphan receptor A	zinc ion binding	Molecular function	-
ARHGEF9	23229	Cdc42 guanine nucleotide exchange factor (GEF) 9	ion transmembrane transport	Biological process	-
HLCS	3141	holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)	nuclear lamina	Cellular component	14613969
COPE	11316	coatomer protein complex, subunit epsilon	protein transport	Biological process	-
NME6	10201	NME/NM23 nucleoside diphosphate kinase 6	negative regulation of cell growth	Biological process	10618642
PLAA	9373	phospholipase A2-activating protein	signal transduction	Biological process	9931468
B3GALTL	145173	beta 1,3-galactosyltransferase-like	protein O-linked fucosylation	Biological process	-
CC2D1B	200014	coiled-coil and C2 domain containing 1B	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
AZIN2	113451	antizyme inhibitor 2	putrescine transport	Biological process	-
AKAP8	10270	A kinase (PRKA) anchor protein 8	nuclear matrix	Cellular component	-
ATP6V0D2	245972	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2	insulin receptor signaling pathway	Biological process	-
NOTCH1	4851	notch 1	forebrain development	Biological process	-
FN1	2335	fibronectin 1	collagen binding	Molecular function	3024962
ANKRD27	84079	ankyrin repeat domain 27 (VPS9 domain)	Rab GTPase binding	Molecular function	16525121
TFPT	29844	TCF3 (E2A) fusion partner (in childhood Leukemia)	Ino80 complex	Cellular component	21303910
CCL5	6352	chemokine (C-C motif) ligand 5	exocytosis	Biological process	10734056
TNRC6A	27327	trinucleotide repeat containing 6A	cytoplasmic mRNA processing body	Cellular component	20616046
GFER	2671	growth factor, augmenter of liver regeneration	growth factor activity	Molecular function	-
VPS11	55823	vacuolar protein sorting 11 homolog (S. cerevisiae)	endosomal vesicle fusion	Biological process	21148287
B3GALTL	145173	beta 1,3-galactosyltransferase-like	cellular protein metabolic process	Biological process	-
HHEX	3087	hematopoietically expressed homeobox	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	15016828
LRRK2	120892	leucine-rich repeat kinase 2	peroxidase inhibitor activity	Molecular function	21850687
NDUFA6	4700	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa	small molecule metabolic process	Biological process	-
BRD7	29117	bromodomain containing 7	p53 binding	Molecular function	20228809
SH2D4A	63898	SH2 domain containing 4A	protein binding	Molecular function	16189514
CACNA1H	8912	calcium channel, voltage-dependent, T type, alpha 1H subunit	muscle organ development	Biological process	9670923
ACVR1	90	activin A receptor, type I	activin receptor complex	Cellular component	8242742
ZNF558	148156	zinc finger protein 558	regulation of transcription, DNA-templated	Biological process	-
IL16	3603	interleukin 16	immune response	Biological process	9144227
CDC25A	993	cell division cycle 25A	cellular response to UV	Biological process	19966869
UGT1A8	54576	UDP glucuronosyltransferase 1 family, polypeptide A8	xenobiotic glucuronidation	Biological process	20056724
EYA2	2139	EYA transcriptional coactivator and phosphatase 2	transcription, DNA-templated	Biological process	-
TRIOBP	11078	TRIO and F-actin binding protein	ubiquitin protein ligase binding	Molecular function	18194665
INPP5E	56623	inositol polyphosphate-5-phosphatase, 72 kDa	Golgi cisterna membrane	Cellular component	-
INPP5K	51763	inositol polyphosphate-5-phosphatase K	negative regulation of glycogen (starch) synthase activity	Biological process	-
FGF19	9965	fibroblast growth factor 19	insulin receptor signaling pathway	Biological process	-
TRIM36	55521	tripartite motif containing 36	ubiquitin-protein transferase activity	Molecular function	-
PCDHAC2	56134	protocadherin alpha subfamily C, 2	homophilic cell adhesion via plasma membrane adhesion molecules	Biological process	-
NCKAP1	10787	NCK-associated protein 1	establishment or maintenance of actin cytoskeleton polarity	Biological process	-
TAF1B	9014	TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa	protein binding	Molecular function	17318177
AMBP	259	alpha-1-microglobulin/bikunin precursor	heme catabolic process	Biological process	11877257
KLHL20	27252	kelch-like family member 20	actin cytoskeleton	Cellular component	10888605
MECP2	4204	methyl CpG binding protein 2	respiratory gaseous exchange	Biological process	-
PHF23	79142	PHD finger protein 23	zinc ion binding	Molecular function	-
CEP70	80321	centrosomal protein 70kDa	nuclear membrane	Cellular component	-
TACC2	10579	transforming, acidic coiled-coil containing protein 2	microtubule cytoskeleton organization	Biological process	-
ACOT9	23597	acyl-CoA thioesterase 9	acyl-CoA metabolic process	Biological process	-
PTK2	5747	protein tyrosine kinase 2	positive regulation of protein kinase B signaling	Biological process	15166238
APLN	8862	apelin	extracellular region	Cellular component	-
PLA2G10	8399	phospholipase A2, group X	phosphatidylglycerol acyl-chain remodeling	Biological process	-
KCNN2	3781	potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2	calmodulin binding	Molecular function	-
LEO1	123169	Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	nucleoplasm	Cellular component	-
VTN	7448	vitronectin	receptor-mediated endocytosis	Biological process	-
CMKLR1	1240	chemerin chemokine-like receptor 1	G-protein coupled receptor signaling pathway	Biological process	9603476
TRPM7	54822	transient receptor potential cation channel, subfamily M, member 7	calcium ion transmembrane transport	Biological process	-
ADAMTS3	9508	ADAM metallopeptidase with thrombospondin type 1 motif, 3	collagen catabolic process	Biological process	11408482
FRRS1	391059	ferric-chelate reductase 1	oxidation-reduction process	Biological process	-
ZYG11B	79699	zyg-11 family member B, cell cycle regulator	Cul2-RING ubiquitin ligase complex	Cellular component	-
PKLR	5313	pyruvate kinase, liver and RBC	response to lithium ion	Biological process	-
HIST1H4E	8367	histone cluster 1, H4e	protein binding	Molecular function	10220385
SNCA	6622	synuclein, alpha (non A4 component of amyloid precursor)	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	Molecular function	10818098
DMC1	11144	DNA meiotic recombinase 1	oocyte maturation	Biological process	-
ESR1	2099	estrogen receptor 1	negative regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	16043358
GLRB	2743	glycine receptor, beta	startle response	Biological process	11929858
BTBD1	53339	BTB (POZ) domain containing 1	protein ubiquitination	Biological process	-
HCFC1	3054	host cell factor C1	release from viral latency	Biological process	10675337
AQP5	362	aquaporin 5	transmembrane transport	Biological process	-
MAPKAPK5	8550	mitogen-activated protein kinase-activated protein kinase 5	cell surface receptor signaling pathway	Biological process	-
RNF175	285533	ring finger protein 175	protein ubiquitination	Biological process	-
ALK	238	anaplastic lymphoma receptor tyrosine kinase	protein complex	Cellular component	23382219
UBIAD1	29914	UbiA prenyltransferase domain containing 1	protein binding	Molecular function	23169578
ZNF606	80095	zinc finger protein 606	transcription, DNA-templated	Biological process	-
MYC	4609	v-myc avian myelocytomatosis viral oncogene homolog	MAPK cascade	Biological process	17873522
ALX4	60529	ALX homeobox 4	HMG box domain binding	Molecular function	-
OR2T27	403239	olfactory receptor, family 2, subfamily T, member 27	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
ESR1	2099	estrogen receptor 1	steroid binding	Molecular function	-
ACVR2A	92	activin A receptor, type IIA	protein binding	Molecular function	10746731
BCL11B	64919	B-cell CLL/lymphoma 11B (zinc finger protein)	olfactory bulb axon guidance	Biological process	-
GTF2B	2959	general transcription factor IIB	transcription from RNA polymerase II promoter	Biological process	-
STEAP3	55240	STEAP family member 3, metalloreductase	transmembrane transport	Biological process	-
ADCY2	108	adenylate cyclase 2 (brain)	G-protein beta/gamma-subunit complex binding	Molecular function	-
CDC20	991	cell division cycle 20	small GTPase mediated signal transduction	Biological process	-
PLEKHM2	23207	pleckstrin homology domain containing, family M (with RUN domain) member 2	kinesin binding	Molecular function	15905402
PLEKHF1	79156	pleckstrin homology domain containing, family F (with FYVE domain) member 1	lysosomal membrane	Cellular component	22115783
COL3A1	1281	collagen, type III, alpha 1	response to cytokine	Biological process	16360482
TACR3	6870	tachykinin receptor 3	plasma membrane	Cellular component	-
RPS28	6234	ribosomal protein S28	viral process	Biological process	-
ZKSCAN2	342357	zinc finger with KRAB and SCAN domains 2	DNA binding	Molecular function	-
LPPR1	54886	lipid phosphate phosphatase-related protein type 1	nervous system development	Biological process	-
NR1H4	9971	nuclear receptor subfamily 1, group H, member 4	nucleoplasm	Cellular component	-
UBQLN1	29979	ubiquilin 1	ER-associated ubiquitin-dependent protein catabolic process	Biological process	19822669
TCF24	100129654	transcription factor 24	DNA binding	Molecular function	-
CLEC6A	93978	C-type lectin domain family 6, member A	positive regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	-
NLK	51701	nemo-like kinase	nucleus	Cellular component	-
ITGB1	3688	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	axon extension	Biological process	-
TULP1	7287	tubby like protein 1	visual perception	Biological process	9462750
H1FOO	132243	H1 histone family, member O, oocyte-specific	nucleosome assembly	Biological process	-
CLDN16	10686	claudin 16	bicellular tight junction	Cellular component	-
CHPF	79586	chondroitin polymerizing factor	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity	Molecular function	-
BGLAP	632	bone gamma-carboxyglutamate (gla) protein	regulation of bone mineralization	Biological process	-
BNIP1	662	BCL2/adenovirus E1B 19kDa interacting protein 1	intracellular membrane-bounded organelle	Cellular component	7954800
PTHLH	5744	parathyroid hormone-like hormone	surfactant homeostasis	Biological process	-
ANAPC2	29882	anaphase promoting complex subunit 2	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	Biological process	-
HKDC1	80201	hexokinase domain containing 1	mannokinase activity	Molecular function	-
CSNK1D	1453	casein kinase 1, delta	endocytosis	Biological process	-
RBM23	55147	RNA binding motif protein 23	RNA binding	Molecular function	-
SLC38A7	55238	solute carrier family 38, member 7	amino acid transmembrane transport	Biological process	-
IL1RL1	9173	interleukin 1 receptor-like 1	negative regulation of T-helper 1 type immune response	Biological process	-
EEF1A1	1915	eukaryotic translation elongation factor 1 alpha 1	cellular protein metabolic process	Biological process	-
SHC4	399694	SHC (Src homology 2 domain containing) family, member 4	intracellular	Cellular component	-
OR4C6	219432	olfactory receptor, family 4, subfamily C, member 6	plasma membrane	Cellular component	-
APOO	79135	apolipoprotein O	extracellular space	Cellular component	22261194
ARV1	64801	ARV1 homolog (S. cerevisiae)	regulation of plasma membrane sterol distribution	Biological process	-
FLVCR1	28982	feline leukemia virus subgroup C cellular receptor 1	erythrocyte differentiation	Biological process	23187127
EFNA1	1942	ephrin-A1	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
HMGN1	3150	high mobility group nucleosome binding domain 1	chromatin	Cellular component	-
USP4	7375	ubiquitin specific peptidase 4 (proto-oncogene)	identical protein binding	Molecular function	22001210
KCNA6	3742	potassium channel, voltage gated shaker related subfamily A, member 6	potassium ion transport	Biological process	2347305
CASP2	835	caspase 2, apoptosis-related cysteine peptidase	ectopic germ cell programmed cell death	Biological process	-
ATP5C1	509	ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1	poly(A) RNA binding	Molecular function	22658674
HSP90AB2P	391634	heat shock protein 90kDa alpha (cytosolic), class B member 2, pseudogene	protein folding	Biological process	-
DLC1	10395	DLC1 Rho GTPase activating protein	regulation of actin cytoskeleton organization	Biological process	17292327
OR4K1	79544	olfactory receptor, family 4, subfamily K, member 1	detection of chemical stimulus involved in sensory perception	Biological process	-
EGFR	1956	epidermal growth factor receptor	innate immune response	Biological process	-
SIRT1	23411	sirtuin 1	PML body	Cellular component	12006491
UROD	7389	uroporphyrinogen decarboxylase	porphyrin-containing compound metabolic process	Biological process	-
PAK2	5062	p21 protein (Cdc42/Rac)-activated kinase 2	signal transduction	Biological process	7744004
PYCARD	29108	PYD and CARD domain containing	positive regulation of interleukin-6 secretion	Biological process	16982856
RHCG	51458	Rh family, C glycoprotein	ammonium transport	Biological process	11062476
SFRP4	6424	secreted frizzled-related protein 4	positive regulation of keratinocyte apoptotic process	Biological process	18938133
CHRNA3	1136	cholinergic receptor, nicotinic, alpha 3 (neuronal)	cell junction	Cellular component	-
IST1	9798	increased sodium tolerance 1 homolog (yeast)	Flemming body	Cellular component	19129479
OPA3	80207	optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)	visual perception	Biological process	15342707
RAB39A	54734	RAB39A, member RAS oncogene family	GTPase activity	Molecular function	-
MAGEA1	4100	melanoma antigen family A1	nucleus	Cellular component	15316101
IKZF1	10320	IKAROS family zinc finger 1 (Ikaros)	natural killer cell differentiation	Biological process	-
ATF5	22809	activating transcription factor 5	transcription factor complex	Cellular component	-
C1QL1	10882	complement component 1, q subcomponent-like 1	locomotory behavior	Biological process	9878755
PRKAA2	5563	protein kinase, AMP-activated, alpha 2 catalytic subunit	cell cycle arrest	Biological process	-
DDX20	11218	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20	RNA processing	Biological process	10601333
BIRC5	332	baculoviral IAP repeat containing 5	condensed chromosome kinetochore	Cellular component	15665297
XPC	7508	xeroderma pigmentosum, complementation group C	nucleus	Cellular component	-
PDIA6	10130	protein disulfide isomerase family A, member 6	protein binding	Molecular function	15466936
CYP26C1	340665	cytochrome P450, family 26, subfamily C, polypeptide 1	neural crest cell development	Biological process	-
MPDZ	8777	multiple PDZ domain protein	cytoplasmic vesicle	Cellular component	-
TNNC1	7134	troponin C type 1 (slow)	cytosol	Cellular component	-
NFKBIA	4792	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	MyD88-dependent toll-like receptor signaling pathway	Biological process	-
LRRTM4	80059	leucine rich repeat transmembrane neuronal 4	alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex	Cellular component	-
ACVR1B	91	activin A receptor, type IB	activin receptor complex	Cellular component	12665502
EFEMP1	2202	EGF containing fibulin-like extracellular matrix protein 1	extracellular matrix	Cellular component	20551380
NELL1	4745	NEL-like 1 (chicken)	regulation of gene expression	Biological process	21723284
MTERF4	130916	mitochondrial transcription termination factor 4	regulation of transcription, DNA-templated	Biological process	-
BLOC1S1	2647	biogenesis of lysosomal organelles complex-1, subunit 1	melanosome organization	Biological process	15102850
JUP	3728	junction plakoglobin	cytoskeletal anchoring at plasma membrane	Biological process	22889254
FCGR3A	2214	Fc fragment of IgG, low affinity IIIa, receptor (CD16a)	immune response	Biological process	2138330
TBX4	9496	T-box 4	lung development	Biological process	-
ERP29	10961	endoplasmic reticulum protein 29	positive regulation of gene expression	Biological process	22064321
ZNF165	7718	zinc finger protein 165	transcription, DNA-templated	Biological process	-
SLC29A3	55315	solute carrier family 29 (equilibrative nucleoside transporter), member 3	nucleoside transmembrane transport	Biological process	-
GJA10	84694	gap junction protein, alpha 10, 62kDa	plasma membrane	Cellular component	-
CASP12	100506742	caspase 12 (gene/pseudogene)	IPAF inflammasome complex	Cellular component	-
ZNF594	84622	zinc finger protein 594	transcription, DNA-templated	Biological process	-
STX10	8677	syntaxin 10	vesicle fusion	Biological process	-
H2AFX	3014	H2A histone family, member X	double-strand break repair via homologous recombination	Biological process	-
ST8SIA6	338596	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6	ganglioside biosynthetic process	Biological process	11980897
DAB2	1601	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)	negative regulation of protein localization to plasma membrane	Biological process	19581412
ZBTB42	100128927	zinc finger and BTB domain containing 42	cytoplasm	Cellular component	-
TNIK	23043	TRAF2 and NCK interacting kinase	protein serine/threonine kinase activity	Molecular function	10521462
NTSR1	4923	neurotensin receptor 1 (high affinity)	integral component of plasma membrane	Cellular component	8381365
PARK7	11315	parkinson protein 7	positive regulation of protein homodimerization activity	Biological process	24947010
OSR1	130497	odd-skipped related transciption factor 1	nucleic acid binding	Molecular function	-
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	embryonic foregut morphogenesis	Biological process	-
SUMO1	7341	small ubiquitin-like modifier 1	negative regulation of DNA binding	Biological process	15637059
PTPN22	26191	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	perinuclear region of cytoplasm	Cellular component	10068674
OAZ3	51686	ornithine decarboxylase antizyme 3	regulation of cellular amino acid metabolic process	Biological process	-
APOA1BP	128240	apolipoprotein A-I binding protein	NADHX epimerase activity	Molecular function	-
POU3F3	5455	POU class 3 homeobox 3	metanephric loop of Henle development	Biological process	-
PAK7	57144	p21 protein (Cdc42/Rac)-activated kinase 7	learning	Biological process	-
ADRB1	153	adrenoceptor beta 1	lipid homeostasis	Biological process	-
MTF1	4520	metal-regulatory transcription factor 1	nucleoplasm	Cellular component	-
AGPAT5	55326	1-acylglycerol-3-phosphate O-acyltransferase 5	small molecule metabolic process	Biological process	-
NEU4	129807	sialidase 4	sphingolipid metabolic process	Biological process	-
RPSA	3921	ribosomal protein SA	viral life cycle	Biological process	-
BGN	633	biglycan	Golgi lumen	Cellular component	-
SDC3	9672	syndecan 3	phototransduction, visible light	Biological process	-
PRICKLE4	29964	prickle homolog 4 (Drosophila)	zinc ion binding	Molecular function	-
PDCD10	11235	programmed cell death 10	stress fiber assembly	Biological process	20332113
LPP	4026	LIM domain containing preferred translocation partner in lipoma	zinc ion binding	Molecular function	-
PSMD14	10213	proteasome (prosome, macropain) 26S subunit, non-ATPase, 14	cellular nitrogen compound metabolic process	Biological process	-
ZACN	353174	zinc activated ligand-gated ion channel	zinc ion binding	Molecular function	12381728
GTF2E2	2961	general transcription factor IIE, polypeptide 2, beta 34kDa	transcription factor TFIIE complex	Cellular component	-
ATP6V0E1	8992	ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1	response to amino acid	Biological process	-
YWHAH	7533	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta	cytoplasmic vesicle membrane	Cellular component	-
ENTPD5	957	ectonucleoside triphosphate diphosphohydrolase 5	cell proliferation	Biological process	-
HCN4	10021	hyperpolarization activated cyclic nucleotide gated potassium channel 4	terminal bouton	Cellular component	-
HCST	10870	hematopoietic cell signal transducer	plasma membrane	Cellular component	-
TLR8	51311	toll-like receptor 8	double-stranded RNA binding	Molecular function	16111635
KIF27	55582	kinesin family member 27	ATP binding	Molecular function	-
SEC14L2	23541	SEC14-like 2 (S. cerevisiae)	transport	Biological process	-
ADGRF2	222611	adhesion G protein-coupled receptor F2	G-protein coupled receptor activity	Molecular function	-
RBFOX2	23543	RNA binding protein, fox-1 homolog (C. elegans) 2	regulation of alternative mRNA splicing, via spliceosome	Biological process	-
JUND	3727	jun D proto-oncogene	enzyme binding	Molecular function	23382074
PARK7	11315	parkinson protein 7	glycolate biosynthetic process	Biological process	22523093
RPA2	6118	replication protein A2, 32kDa	nucleotide-excision repair, DNA damage removal	Biological process	-
SRXN1	140809	sulfiredoxin 1	sulfiredoxin activity	Molecular function	-
PRKCE	5581	protein kinase C, epsilon	mitochondrion	Cellular component	-
HDAC10	83933	histone deacetylase 10	negative regulation of transcription, DNA-templated	Biological process	11726666
ARHGEF6	9459	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6	protein binding	Molecular function	11864573
CYFIP1	23191	cytoplasmic FMR1 interacting protein 1	SCAR complex	Cellular component	21107423
NANOS3	342977	nanos homolog 3 (Drosophila)	negative regulation of translation	Biological process	24736845
SLC30A6	55676	solute carrier family 30 (zinc transporter), member 6	Golgi to endosome transport	Biological process	-
ZNF780A	284323	zinc finger protein 780A	regulation of transcription, DNA-templated	Biological process	-
SETMAR	6419	SET domain and mariner transposase fusion gene	replication fork processing	Biological process	20457750
ENPP5	59084	ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)	metal ion binding	Molecular function	-
IFIT2	3433	interferon-induced protein with tetratricopeptide repeats 2	cytosol	Cellular component	-
GNG2	54331	guanine nucleotide binding protein (G protein), gamma 2	cell proliferation	Biological process	-
CCNE1	898	cyclin E1	mitotic cell cycle	Biological process	-
NCAPG	64151	non-SMC condensin I complex, subunit G	condensin complex	Cellular component	11136719
HTR2B	3357	5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled	cardiac muscle hypertrophy	Biological process	-
PAK1	5058	p21 protein (Cdc42/Rac)-activated kinase 1	filamentous actin	Cellular component	9395435
CDK11B	984	cyclin-dependent kinase 11B	regulation of cell growth	Biological process	10882096
SCN5A	6331	sodium channel, voltage gated, type V alpha subunit	ventricular cardiac muscle cell action potential	Biological process	18065446
ICOSLG	23308	inducible T-cell co-stimulator ligand	plasma membrane	Cellular component	-
SIRT2	22933	sirtuin 2	negative regulation of fat cell differentiation	Biological process	-
NCOA1	8648	nuclear receptor coactivator 1	nucleoplasm	Cellular component	-
PKD2	5311	polycystic kidney disease 2 (autosomal dominant)	heart development	Biological process	11891195
STXBP2	6813	syntaxin binding protein 2	specific granule	Cellular component	18588921
SETD8	387893	SET domain containing (lysine methyltransferase) 8	histone lysine methylation	Biological process	-
GRK5	2869	G protein-coupled receptor kinase 5	focal adhesion	Cellular component	-
ANXA9	8416	annexin A9	synaptic transmission	Biological process	10899159
SGPP1	81537	sphingosine-1-phosphate phosphatase 1	extrinsic apoptotic signaling pathway	Biological process	-
LIM2	3982	lens intrinsic membrane protein 2, 19kDa	lens development in camera-type eye	Biological process	-
GNL3L	54552	guanine nucleotide binding protein-like 3 (nucleolar)-like	protein binding	Molecular function	21132010
CXCL12	6387	chemokine (C-X-C motif) ligand 12	cell adhesion	Biological process	10198043
SOX7	83595	SRY (sex determining region Y)-box 7	sequence-specific DNA binding	Molecular function	-
SOX3	6658	SRY (sex determining region Y)-box 3	negative regulation of neuron differentiation	Biological process	-
NME5	8382	NME/NM23 family member 5	nucleoside metabolic process	Biological process	9742940
ADPRHL2	54936	ADP-ribosylhydrolase like 2	nucleoplasm	Cellular component	-
RAMP2	10266	receptor (G protein-coupled) activity modifying protein 2	heart development	Biological process	-
APOA4	337	apolipoprotein A-IV	neuron projection regeneration	Biological process	-
NLRP1	22861	NLR family, pyrin domain containing 1	NLRP1 inflammasome complex	Cellular component	20303873
RAB35	11021	RAB35, member RAS oncogene family	endocytic recycling	Biological process	-
ICAM5	7087	intercellular adhesion molecule 5, telencephalin	plasma membrane	Cellular component	8995416
EGFR	1956	epidermal growth factor receptor	magnesium ion homeostasis	Biological process	-
SLC11A1	6556	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1	manganese ion transmembrane transport	Biological process	-
EDN3	1908	endothelin 3	intracellular	Cellular component	1917960
PGAM1	5223	phosphoglycerate mutase 1 (brain)	gluconeogenesis	Biological process	-
C5AR1	728	complement component 5a receptor 1	activation of phospholipase C activity	Biological process	7649993
CLTA	1211	clathrin, light chain A	clathrin-coated endocytic vesicle membrane	Cellular component	-
ABCB10	23456	ATP-binding cassette, sub-family B (MDR/TAP), member 10	metabolic process	Biological process	-
AQP6	363	aquaporin 6, kidney specific	transport	Biological process	8812490
PTPN22	26191	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	protein tyrosine phosphatase activity	Molecular function	10068674
SMARCA2	6595	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	histone binding	Molecular function	-
TBX19	9095	T-box 19	anatomical structure morphogenesis	Biological process	9888994
MOS	4342	v-mos Moloney murine sarcoma viral oncogene homolog	establishment of meiotic spindle orientation	Biological process	-
LTB4R	1241	leukotriene B4 receptor	plasma membrane	Cellular component	-
ANXA2	302	annexin A2	Rab GTPase binding	Molecular function	-
FOXD4	2298	forkhead box D4	transcription from RNA polymerase II promoter	Biological process	-
FGF1	2246	fibroblast growth factor 1 (acidic)	insulin receptor signaling pathway	Biological process	-
RBPJ	3516	recombination signal binding protein for immunoglobulin kappa J region	epithelial to mesenchymal transition	Biological process	-
MECP2	4204	methyl CpG binding protein 2	post-embryonic development	Biological process	-
DPEP1	1800	dipeptidase 1 (renal)	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	Molecular function	20435919
TYMS	7298	thymidylate synthetase	pyrimidine nucleobase metabolic process	Biological process	-
RNF4	6047	ring finger protein 4	sequence-specific DNA binding transcription factor activity	Molecular function	9710597
CYP1A2	1544	cytochrome P450, family 1, subfamily A, polypeptide 2	oxidative demethylation	Biological process	18619574
ALOX15B	247	arachidonate 15-lipoxygenase, type B	iron ion binding	Molecular function	24497644
RABEP1	9135	rabaptin, RAB GTPase binding effector protein 1	positive regulation of GTPase activity	Biological process	-
APTX	54840	aprataxin	phosphoglycolate phosphatase activity	Molecular function	17519253
MEF2C	4208	myocyte enhancer factor 2C	glomerulus morphogenesis	Biological process	-
EWSR1	2130	EWS RNA-binding protein 1	protein binding	Molecular function	16189514
RBM15B	29890	RNA binding motif protein 15B	poly(A) RNA binding	Molecular function	22658674
AGPAT1	10554	1-acylglycerol-3-phosphate O-acyltransferase 1	positive regulation of cellular metabolic process	Biological process	-
RYR3	6263	ryanodine receptor 3	protein homotetramerization	Biological process	-
SLC38A2	54407	solute carrier family 38, member 2	neurotransmitter secretion	Biological process	-
SLA	6503	Src-like-adaptor	endosome	Cellular component	-
CPSF3	51692	cleavage and polyadenylation specific factor 3, 73kDa	mRNA cleavage and polyadenylation specificity factor complex	Cellular component	18305108
SPTBN1	6711	spectrin, beta, non-erythrocytic 1	phospholipid binding	Molecular function	-
ST6GALNAC6	30815	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6	dolichol-linked oligosaccharide biosynthetic process	Biological process	-
GNAI1	2770	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway	Biological process	-
ACACA	31	acetyl-CoA carboxylase alpha	triglyceride biosynthetic process	Biological process	-
EIF4A3	9775	eukaryotic translation initiation factor 4A3	RNA splicing	Biological process	-
LAMTOR1	55004	late endosomal/lysosomal adaptor, MAPK and MTOR activator 1	extracellular exosome	Cellular component	19056867
CHST11	50515	carbohydrate (chondroitin 4) sulfotransferase 11	small molecule metabolic process	Biological process	-
PCM1	5108	pericentriolar material 1	cytoplasmic microtubule organization	Biological process	22797915
ATP1B1	481	ATPase, Na+/K+ transporting, beta 1 polypeptide	ATPase activator activity	Molecular function	10636900
FST	10468	follistatin	cytoplasm	Cellular component	-
SERPINE3	647174	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3	extracellular space	Cellular component	-
RQCD1	9125	RCD1 required for cell differentiation1 homolog (S. pombe)	protein binding	Molecular function	18180299
STAR	6770	steroidogenic acute regulatory protein	fractalkine metabolic process	Biological process	-
DTL	51514	denticleless E3 ubiquitin protein ligase homolog (Drosophila)	chromosome	Cellular component	-
RASA1	5921	RAS p21 protein activator (GTPase activating protein) 1	protein binding	Molecular function	1314164
HHEX	3087	hematopoietically expressed homeobox	positive regulation of transcription from RNA polymerase II promoter	Biological process	12655000
RHBDF2	79651	rhomboid 5 homolog 2 (Drosophila)	endoplasmic reticulum membrane	Cellular component	-
UQCRC1	7384	ubiquinol-cytochrome c reductase core protein I	metal ion binding	Molecular function	-
C5	727	complement component 5	chemotaxis	Biological process	10820279
MAPK6	5597	mitogen-activated protein kinase 6	cytoplasm	Cellular component	-
BRI3BP	140707	BRI3 binding protein	integral component of membrane	Cellular component	-
F10	2159	coagulation factor X	calcium ion binding	Molecular function	-
CCL5	6352	chemokine (C-C motif) ligand 5	positive regulation of viral genome replication	Biological process	10488085
RRP1B	23076	ribosomal RNA processing 1B	cytosol	Cellular component	16780588
XIAP	331	X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase	regulation of nucleotide-binding oligomerization domain containing signaling pathway	Biological process	20888210
PRRG4	79056	proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)	integral component of membrane	Cellular component	11171957
SGK1	6446	serum/glucocorticoid regulated kinase 1	regulation of catalytic activity	Biological process	20530112
NR1H2	7376	nuclear receptor subfamily 1, group H, member 2	positive regulation of pancreatic juice secretion	Biological process	-
RANBP2	5903	RAN binding protein 2	post-translational protein modification	Biological process	-
TNFSF15	9966	tumor necrosis factor (ligand) superfamily, member 15	activation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	11911831
THY1	7070	Thy-1 cell surface antigen	T cell receptor signaling pathway	Biological process	-
PRPH	5630	peripherin	neurofilament	Cellular component	-
ZNF239	8187	zinc finger protein 239	transcription, DNA-templated	Biological process	-
EDNRB	1910	endothelin receptor type B	positive regulation of penile erection	Biological process	-
TWIST1	7291	twist family bHLH transcription factor 1	cardiac neural crest cell migration involved in outflow tract morphogenesis	Biological process	-
MYO5A	4644	myosin VA (heavy chain 12, myoxin)	peroxisome	Cellular component	24006491
CIRBP	1153	cold inducible RNA binding protein	nucleus	Cellular component	-
NLGN4Y	22829	neuroligin 4, Y-linked	vocalization behavior	Biological process	18628683
NSF	4905	N-ethylmaleimide-sensitive factor	plasma membrane	Cellular component	15613468
EMILIN2	84034	elastin microfibril interfacer 2	cell adhesion	Biological process	-
WASF2	10163	WAS protein family, member 2	SCAR complex	Cellular component	21107423
MEN1	4221	multiple endocrine neoplasia I	negative regulation of cyclin-dependent protein serine/threonine kinase activity	Biological process	15640349
KRTAP2-4	85294	keratin associated protein 2-4	keratin filament	Cellular component	-
MYH14	79784	myosin, heavy chain 14, non-muscle	skeletal muscle contraction	Biological process	21480433
RASAL1	8437	RAS protein activator like 1 (GAP1 like)	cytosol	Cellular component	16009725
ITPKA	3706	inositol-trisphosphate 3-kinase A	protein phosphorylation	Biological process	-
CDKN1A	1026	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	negative regulation of apoptotic process	Biological process	-
UGT1A8	54576	UDP glucuronosyltransferase 1 family, polypeptide A8	protein heterodimerization activity	Molecular function	20610558
ZNF711	7552	zinc finger protein 711	protein binding	Molecular function	20346720
CACNA1I	8911	calcium channel, voltage-dependent, T type, alpha 1I subunit	low voltage-gated calcium channel activity	Molecular function	-
PSMB5	5693	proteasome (prosome, macropain) subunit, beta type, 5	cytosol	Cellular component	-
CCND1	595	cyclin D1	positive regulation of G2/M transition of mitotic cell cycle	Biological process	19124461
STK25	10494	serine/threonine kinase 25	protein phosphorylation	Biological process	17657516
TIMP4	7079	TIMP metallopeptidase inhibitor 4	biological_process	Biological process	-
RNASE12	493901	ribonuclease, RNase A family, 12 (non-active)	nucleic acid binding	Molecular function	-
MFI2	4241	antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5	positive regulation of extracellular matrix disassembly	Biological process	16713448
YBEY	54059	ybeY metallopeptidase (putative)	rRNA processing	Biological process	-
KLHL3	26249	kelch-like family member 3	structural molecule activity	Molecular function	10843806
HP1BP3	50809	heterochromatin protein 1, binding protein 3	regulation of nucleus size	Biological process	24830416
GART	2618	phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase	tetrahydrofolate biosynthetic process	Biological process	-
SRSF2	6427	serine/arginine-rich splicing factor 2	transcription corepressor activity	Molecular function	15652350
CEL	1056	carboxyl ester lipase	hydrolase activity	Molecular function	2265692
DHRS2	10202	dehydrogenase/reductase (SDR family) member 2	nuclear envelope	Cellular component	11997086
RAB11FIP3	9727	RAB11 family interacting protein 3 (class II)	vesicle-mediated transport	Biological process	16148947
RBMS1	5937	RNA binding motif, single stranded interacting protein 1	protein binding	Molecular function	10869558
PLK2	10769	polo-like kinase 2	G1/S transition of mitotic cell cycle	Biological process	15242618
SLC31A1	1317	solute carrier family 31 (copper transporter), member 1	copper uptake transmembrane transporter activity	Molecular function	-
KCNH1	3756	potassium channel, voltage gated eag related subfamily H, member 1	phosphorelay sensor kinase activity	Molecular function	-
RHOH	399	ras homolog family member H	regulation of transcription, DNA-templated	Biological process	11809807
WAS	7454	Wiskott-Aldrich syndrome	epidermis development	Biological process	8069912
PRKCG	5582	protein kinase C, gamma	synaptic transmission	Biological process	-
KRAS	3845	Kirsten rat sarcoma viral oncogene homolog	fibroblast growth factor receptor signaling pathway	Biological process	-
IGFBP4	3487	insulin-like growth factor binding protein 4	type B pancreatic cell proliferation	Biological process	-
FRS2	10818	fibroblast growth factor receptor substrate 2	ventricular septum development	Biological process	-
CPEB4	80315	cytoplasmic polyadenylation element binding protein 4	postsynaptic density	Cellular component	-
GDNF	2668	glial cell derived neurotrophic factor	protein binding	Molecular function	25416956
PEX19	5824	peroxisomal biogenesis factor 19	integral component of membrane	Cellular component	10051604
MSH2	4436	mutS homolog 2	somatic hypermutation of immunoglobulin genes	Biological process	-
PEX7	5191	peroxisomal biogenesis factor 7	enzyme binding	Molecular function	11931631
WNT2	7472	wingless-type MMTV integration site family member 2	positive regulation of fibroblast proliferation	Biological process	19734317
IGSF6	10261	immunoglobulin superfamily, member 6	immune response	Biological process	9809579
VAMP8	8673	vesicle-associated membrane protein 8	recycling endosome	Cellular component	18570918
BDH1	622	3-hydroxybutyrate dehydrogenase, type 1	response to insulin	Biological process	-
KLF10	7071	Kruppel-like factor 10	sequence-specific DNA binding transcription factor activity	Molecular function	10816551
CHRNA4	1137	cholinergic receptor, nicotinic, alpha 4 (neuronal)	response to hypoxia	Biological process	12189247
LAMTOR1	55004	late endosomal/lysosomal adaptor, MAPK and MTOR activator 1	protein complex scaffold	Molecular function	22980980
DTNBP1	84062	dystrobrevin binding protein 1	melanosome organization	Biological process	22203680
SAR1B	51128	secretion associated, Ras related GTPase 1B	protein N-linked glycosylation via asparagine	Biological process	-
DFNB31	25861	deafness, autosomal recessive 31	protein binding	Molecular function	17584769
CPOX	1371	coproporphyrinogen oxidase	response to iron ion	Biological process	-
ACADL	33	acyl-CoA dehydrogenase, long chain	fatty acid beta-oxidation using acyl-CoA dehydrogenase	Biological process	-
ATP6V1A	523	ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A	mitochondrion	Cellular component	-
SLC25A17	10478	solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17	AMP transmembrane transporter activity	Molecular function	22185573
AKIP1	56672	A kinase (PRKA) interacting protein 1	nucleoplasm	Cellular component	-
HEXA	3073	hexosaminidase A (alpha polypeptide)	keratan sulfate metabolic process	Biological process	-
TNNT1	7138	troponin T type 1 (skeletal, slow)	cytosol	Cellular component	-
PACRGL	133015	PARK2 co-regulated-like	protein binding	Molecular function	25416956
GNB1	2782	guanine nucleotide binding protein (G protein), beta polypeptide 1	G-protein coupled acetylcholine receptor signaling pathway	Biological process	8717044
DAB2IP	153090	DAB2 interacting protein	negative regulation of MAP kinase activity	Biological process	20154697
DCN	1634	decorin	skeletal muscle tissue development	Biological process	-
PSD	5662	pleckstrin and Sec7 domain containing	ruffle	Cellular component	-
HIST1H4C	8364	histone cluster 1, H4c	DNA replication-independent nucleosome assembly	Biological process	14718166
NPY5R	4889	neuropeptide Y receptor Y5	positive regulation of smooth muscle cell proliferation	Biological process	-
ATP1A3	478	ATPase, Na+/K+ transporting, alpha 3 polypeptide	adult locomotory behavior	Biological process	-
ADCYAP1R1	117	adenylate cyclase activating polypeptide 1 (pituitary) receptor type I	neuropeptide binding	Molecular function	-
GDNF	2668	glial cell derived neurotrophic factor	regulation of morphogenesis of a branching structure	Biological process	-
CYP2D6	1565	cytochrome P450, family 2, subfamily D, polypeptide 6	coumarin metabolic process	Biological process	19438707
GLO1	2739	glyoxalase I	carbohydrate metabolic process	Biological process	-
PRKD1	5587	protein kinase D1	intracellular signal transduction	Biological process	18059339
SRSF7	6432	serine/arginine-rich splicing factor 7	nucleotide binding	Molecular function	-
CHCHD1	118487	coiled-coil-helix-coiled-coil-helix domain containing 1	poly(A) RNA binding	Molecular function	22681889
TMEM39A	55254	transmembrane protein 39A	integral component of membrane	Cellular component	-
CELA3B	23436	chymotrypsin-like elastase family, member 3B	peptidase activity	Molecular function	2460440
ELOVL1	64834	ELOVL fatty acid elongase 1	protein binding	Molecular function	20937905
METTL14	57721	methyltransferase like 14	nucleus	Cellular component	24316715
ATF1	466	activating transcription factor 1	ATF1-ATF4 transcription factor complex	Cellular component	12871976
ATP1A1	476	ATPase, Na+/K+ transporting, alpha 1 polypeptide	protein domain specific binding	Molecular function	-
RHOBTB3	22836	Rho-related BTB domain containing 3	small GTPase mediated signal transduction	Biological process	-
CD46	4179	CD46 molecule, complement regulatory protein	interleukin-10 production	Biological process	23086448
STEAP4	79689	STEAP family member 4	extracellular exosome	Cellular component	23533145
ARL3	403	ADP-ribosylation factor-like 3	GTPase activity	Molecular function	-
PLG	5340	plasminogen	blood microparticle	Cellular component	22516433
RSPH1	89765	radial spoke head 1 homolog (Chlamydomonas)	cytosol	Cellular component	16780588
EGFR	1956	epidermal growth factor receptor	learning or memory	Biological process	-
GCK	2645	glucokinase (hexokinase 4)	positive regulation of insulin secretion	Biological process	8132752
POLR2D	5433	polymerase (RNA) II (DNA directed) polypeptide D	7-methylguanosine mRNA capping	Biological process	-
MYH6	4624	myosin, heavy chain 6, cardiac muscle, alpha	BMP signaling pathway	Biological process	-
RNASEH2C	84153	ribonuclease H2, subunit C	nucleus	Cellular component	-
TAPBP	6892	TAP binding protein (tapasin)	integral component of lumenal side of endoplasmic reticulum membrane	Cellular component	-
MAGEA8	4107	melanoma antigen family A8	molecular_function	Molecular function	-
SIRT1	23411	sirtuin 1	positive regulation of macroautophagy	Biological process	18296641
PDE3A	5139	phosphodiesterase 3A, cGMP-inhibited	lipid metabolic process	Biological process	8921398
SCGB1A1	7356	secretoglobin, family 1A, member 1 (uteroglobin)	female pregnancy	Biological process	10587371
DAB2IP	153090	DAB2 interacting protein	tube formation	Biological process	19033661
ABL2	27	ABL proto-oncogene 2, non-receptor tyrosine kinase	neuromuscular process controlling balance	Biological process	-
BCL2L1	598	BCL2-like 1	release of cytochrome c from mitochondria	Biological process	9843949
INS	3630	insulin	negative regulation of NAD(P)H oxidase activity	Biological process	11443198
CD34	947	CD34 molecule	hemopoiesis	Biological process	15969628
CDKN1A	1026	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	G2/M transition of mitotic cell cycle	Biological process	17553787
REPIN1	29803	replication initiator 1	nuclear origin of replication recognition complex	Cellular component	10606657
IFT52	51098	intraflagellar transport 52	ciliary tip	Cellular component	-
PNPT1	87178	polyribonucleotide nucleotidyltransferase 1	mitochondrial mRNA polyadenylation	Biological process	18083837
VPS18	57617	vacuolar protein sorting 18 homolog (S. cerevisiae)	endosome organization	Biological process	18799622
SLC9A1	6548	solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1	cell migration	Biological process	17565280
ALX4	60529	ALX homeobox 4	transcription, DNA-templated	Biological process	-
ANXA1	301	annexin A1	signal transduction	Biological process	16130169
PNPLA4	8228	patatin-like phospholipase domain containing 4	molecular_function	Molecular function	-
SH3PXD2B	285590	SH3 and PX domains 2B	SH2 domain binding	Molecular function	-
PLRG1	5356	pleiotropic regulator 1	signal transduction	Biological process	9765207
TYR	7299	tyrosinase	thymus development	Biological process	-
ARL4A	10124	ADP-ribosylation factor-like 4A	plasma membrane	Cellular component	17398095
FGFR2	2263	fibroblast growth factor receptor 2	organ morphogenesis	Biological process	-
ATP4B	496	ATPase, H+/K+ exchanging, beta polypeptide	transmembrane transport	Biological process	-
H2AFY2	55506	H2A histone family, member Y2	nuclear chromatin	Cellular component	19734898
ZNF146	7705	zinc finger protein 146	nucleolus	Cellular component	-
ZNF223	7766	zinc finger protein 223	metal ion binding	Molecular function	-
TFAP2B	7021	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	magnesium ion homeostasis	Biological process	-
OPLAH	26873	5-oxoprolinase (ATP-hydrolysing)	glutathione derivative biosynthetic process	Biological process	-
SMAD7	4092	SMAD family member 7	collagen binding	Molecular function	-
SLC7A8	23428	solute carrier family 7 (amino acid transporter light chain, L system), member 8	toxin transporter activity	Molecular function	12117417
UQCRQ	27089	ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa	hypothalamus development	Biological process	-
TEC	7006	tec protein tyrosine kinase	non-membrane spanning protein tyrosine kinase activity	Molecular function	10518561
NLRP12	91662	NLR family, pyrin domain containing 12	cellular response to cytokine stimulus	Biological process	-
EDARADD	128178	EDAR-associated death domain	hair follicle development	Biological process	-
SOD2	6648	superoxide dismutase 2, mitochondrial	negative regulation of neuron apoptotic process	Biological process	17251466
TGIF1	7050	TGFB-induced factor homeobox 1	retina development in camera-type eye	Biological process	-
RPS27A	6233	ribosomal protein S27a	gene expression	Biological process	-
FAM32A	26017	family with sequence similarity 32, member A	biological_process	Biological process	-
CLVS2	134829	clavesin 2	clathrin-coated endocytic vesicle membrane	Cellular component	-
RAB17	64284	RAB17, member RAS oncogene family	melanosome transport	Biological process	-
INPP5K	51763	inositol polyphosphate-5-phosphatase K	negative regulation of glucose transport	Biological process	12556481
PRAMEF7	441871	PRAME family member 7	negative regulation of apoptotic process	Biological process	-
MEF2A	4205	myocyte enhancer factor 2A	toll-like receptor 5 signaling pathway	Biological process	-
APOBEC1	339	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	negative regulation of methylation-dependent chromatin silencing	Biological process	-
SFTPB	6439	surfactant protein B	respiratory gaseous exchange	Biological process	-
C3orf58	205428	chromosome 3 open reading frame 58	extracellular space	Cellular component	23784961
CASP9	842	caspase 9, apoptosis-related cysteine peptidase	intrinsic apoptotic signaling pathway in response to DNA damage	Biological process	15657060
ADARB1	104	adenosine deaminase, RNA-specific, B1	RNA binding	Molecular function	9111310
ASNS	440	asparagine synthetase (glutamine-hydrolyzing)	cellular response to glucose starvation	Biological process	10085239
RNF144A	9781	ring finger protein 144A	Golgi apparatus	Cellular component	10942595
LIPC	3990	lipase, hepatic	cholesterol homeostasis	Biological process	1883393
TOM1L2	146691	target of myb1-like 2 (chicken)	protein kinase binding	Molecular function	16479011
GAS6	2621	growth arrest-specific 6	negative regulation of renal albumin absorption	Biological process	-
TRNAU1AP	54952	tRNA selenocysteine 1 associated protein 1	cytoplasm	Cellular component	-
RAPGEF1	2889	Rap guanine nucleotide exchange factor (GEF) 1	Rap guanyl-nucleotide exchange factor activity	Molecular function	21840392
TSPYL1	7259	TSPY-like 1	nucleolus	Cellular component	-
PDGFRA	5156	platelet-derived growth factor receptor, alpha polypeptide	neurotrophin TRK receptor signaling pathway	Biological process	-
TACR1	6869	tachykinin receptor 1	regulation of smooth muscle cell proliferation	Biological process	-
HS3ST4	9951	heparan sulfate (glucosamine) 3-O-sulfotransferase 4	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity	Molecular function	9988767
ASPG	374569	asparaginase	1-alkyl-2-acetylglycerophosphocholine esterase activity	Molecular function	-
JUNB	3726	jun B proto-oncogene	transforming growth factor beta receptor signaling pathway	Biological process	-
PHF2	5253	PHD finger protein 2	nucleoplasm	Cellular component	-
PAFAH1B1	5048	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	vesicle transport along microtubule	Biological process	10729324
PRDM6	93166	PR domain containing 6	nucleus	Cellular component	-
SYNE2	23224	spectrin repeat containing, nuclear envelope 2	cytoskeletal anchoring at nuclear membrane	Biological process	18396275
ULK3	25989	unc-51 like kinase 3	cytosol	Cellular component	-
GAR1	54433	GAR1 ribonucleoprotein	nucleolus	Cellular component	-
SGIP1	84251	SH3-domain GRB2-like (endophilin) interacting protein 1	clathrin-coated vesicle	Cellular component	-
ERBB3	2065	erb-b2 receptor tyrosine kinase 3	endocardial cushion development	Biological process	-
PDIA6	10130	protein disulfide isomerase family A, member 6	protein disulfide isomerase activity	Molecular function	-
PECAM1	5175	platelet/endothelial cell adhesion molecule 1	glomerular endothelium development	Biological process	17464107
MYDGF	56005	myeloid-derived growth factor	positive regulation of angiogenesis	Biological process	25581518
HDAC3	8841	histone deacetylase 3	histone H3-K9 modification	Biological process	-
SLC2A5	6518	solute carrier family 2 (facilitated glucose/fructose transporter), member 5	proton transport	Biological process	-
SMPD2	6610	sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)	integral component of plasma membrane	Cellular component	9520418
SETD1A	9739	SET domain containing 1A	positive regulation of stem cell proliferation	Biological process	-
STX7	8417	syntaxin 7	endocytic vesicle	Cellular component	10564279
ESX1	80712	ESX homeobox 1	negative regulation of transcription from RNA polymerase II promoter	Biological process	15897875
ATRX	546	alpha thalassemia/mental retardation syndrome X-linked	Sertoli cell development	Biological process	-
CD34	947	CD34 molecule	negative regulation of cellular response to heat	Biological process	17505307
NEU2	4759	sialidase 2 (cytosolic sialidase)	exo-alpha-(2->3)-sialidase activity	Molecular function	22228546
DDX58	23586	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	ruffle membrane	Cellular component	19122199
IL4	3565	interleukin 4	regulation of proton transport	Biological process	-
FMNL1	752	formin-like 1	membrane	Cellular component	19946888
ACER2	340485	alkaline ceramidase 2	ceramidase activity	Molecular function	16940153
OXGR1	27199	oxoglutarate (alpha-ketoglutarate) receptor 1	G-protein coupled receptor activity	Molecular function	-
NUP43	348995	nucleoporin 43kDa	small GTPase mediated signal transduction	Biological process	-
SERPINA1	5265	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1	protein binding	Molecular function	11057674
EN2	2020	engrailed homeobox 2	neuron development	Biological process	-
TDO2	6999	tryptophan 2,3-dioxygenase	small molecule metabolic process	Biological process	-
TWIST1	7291	twist family bHLH transcription factor 1	cranial suture morphogenesis	Biological process	11001584
IFNA5	3442	interferon, alpha 5	innate immune response	Biological process	-
ITPR3	3710	inositol 1,4,5-trisphosphate receptor, type 3	signal transduction	Biological process	-
NMNAT1	64802	nicotinamide nucleotide adenylyltransferase 1	nicotinate-nucleotide adenylyltransferase activity	Molecular function	16118205
UCN	7349	urocortin	negative regulation of neuron death	Biological process	-
ANXA5	308	annexin A5	response to organic substance	Biological process	-
NR4A1	3164	nuclear receptor subfamily 4, group A, member 1	fibroblast growth factor receptor signaling pathway	Biological process	-
FIGF	2277	c-fos induced growth factor (vascular endothelial growth factor D)	extracellular space	Cellular component	-
MGST3	4259	microsomal glutathione S-transferase 3	nuclear envelope	Cellular component	-
KRTAP5-8	57830	keratin associated protein 5-8	keratin filament	Cellular component	-
BLOC1S1	2647	biogenesis of lysosomal organelles complex-1, subunit 1	BLOC-1 complex	Cellular component	15102850
CALCOCO1	57658	calcium binding and coiled-coil domain 1	intracellular membrane-bounded organelle	Cellular component	-
GABRA1	2554	gamma-aminobutyric acid (GABA) A receptor, alpha 1	postsynaptic membrane	Cellular component	-
TLR9	54106	toll-like receptor 9	I-kappaB phosphorylation	Biological process	19740627
TNFAIP8L2	79626	tumor necrosis factor, alpha-induced protein 8-like 2	innate immune response	Biological process	-
MDM2	4193	MDM2 proto-oncogene, E3 ubiquitin protein ligase	cellular response to hydrogen peroxide	Biological process	-
PSMB1	5689	proteasome (prosome, macropain) subunit, beta type, 1	programmed cell death	Biological process	-
KAT6B	23522	K(lysine) acetyltransferase 6B	histone acetylation	Biological process	11965546
LITAF	9516	lipopolysaccharide-induced TNF factor	transcription, DNA-templated	Biological process	-
PINX1	54984	PIN2/TERF1 interacting, telomerase inhibitor 1	telomerase inhibitor activity	Molecular function	15381700
GRIN2C	2905	glutamate receptor, ionotropic, N-methyl D-aspartate 2C	N-methyl-D-aspartate selective glutamate receptor activity	Molecular function	-
KCNJ11	3767	potassium channel, inwardly rectifying subfamily J, member 11	response to drug	Biological process	18073297
MAN1A2	10905	mannosidase, alpha, class 1A, member 2	integral component of membrane	Cellular component	-
OR4A15	81328	olfactory receptor, family 4, subfamily A, member 15	plasma membrane	Cellular component	-
SLC43A3	29015	solute carrier family 43, member 3	cellular_component	Cellular component	-
SAA1	6288	serum amyloid A1	negative regulation of inflammatory response	Biological process	9823935
SMAD3	4088	SMAD family member 3	plasma membrane	Cellular component	-
SYT11	23208	synaptotagmin XI	synaptic vesicle exocytosis	Biological process	-
LY96	23643	lymphocyte antigen 96	toll-like receptor 3 signaling pathway	Biological process	-
CCL5	6352	chemokine (C-C motif) ligand 5	positive regulation of T cell proliferation	Biological process	18832695
CDC7	8317	cell division cycle 7	protein binding	Molecular function	12065429
SCN5A	6331	sodium channel, voltage gated, type V alpha subunit	positive regulation of sodium ion transport	Biological process	14500339
PMEPA1	56937	prostate transmembrane protein, androgen induced 1	androgen receptor signaling pathway	Biological process	10873380
ARL11	115761	ADP-ribosylation factor-like 11	small GTPase mediated signal transduction	Biological process	-
RAPGEF2	9693	Rap guanine nucleotide exchange factor (GEF) 2	blood vessel development	Biological process	-
CIR1	9541	corepressor interacting with RBPJ, 1	nuclear speck	Cellular component	-
RGS11	8786	regulator of G-protein signaling 11	termination of G-protein coupled receptor signaling pathway	Biological process	-
SRI	6717	sorcin	negative regulation of transcription regulatory region DNA binding	Biological process	-
FARSB	10056	phenylalanyl-tRNA synthetase, beta subunit	phenylalanyl-tRNA aminoacylation	Biological process	-
UPF3B	65109	UPF3 regulator of nonsense transcripts homolog B (yeast)	cytosol	Cellular component	-
CDON	50937	cell adhesion associated, oncogene regulated	positive regulation of muscle cell differentiation	Biological process	-
TAF15	8148	TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa	protein binding	Molecular function	19124016
SRPK1	6732	SRSF protein kinase 1	protein binding	Molecular function	10196197
AGO3	192669	argonaute RISC catalytic component 3	miRNA loading onto RISC involved in gene silencing by miRNA	Biological process	19966796
SCGB2A1	4246	secretoglobin, family 2A, member 1	extracellular space	Cellular component	16395610
GPER1	2852	G protein-coupled estrogen receptor 1	neuronal action potential	Biological process	-
RPL13AP3	645683	ribosomal protein L13a pseudogene 3	translation	Biological process	-
OR10G2	26534	olfactory receptor, family 10, subfamily G, member 2	sensory perception of smell	Biological process	-
EYA1	2138	EYA transcriptional coactivator and phosphatase 1	cellular protein localization	Biological process	-
HNRNPF	3185	heterogeneous nuclear ribonucleoprotein F	catalytic step 2 spliceosome	Cellular component	11991638
BRIP1	83990	BRCA1 interacting protein C-terminal helicase 1	DNA duplex unwinding	Biological process	11301010
RNASEL	6041	ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)	cytosol	Cellular component	-
ITPR1	3708	inositol 1,4,5-trisphosphate receptor, type 1	post-embryonic development	Biological process	-
TNPO1	3842	transportin 1	protein import into nucleus, translocation	Biological process	9144189
CLN8	2055	ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)	regulation of cell size	Biological process	-
SMARCAD1	56916	SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1	positive regulation of transcription, DNA-templated	Biological process	11031099
CASP2	835	caspase 2, apoptosis-related cysteine peptidase	cytoplasm	Cellular component	-
TRAM1	23471	translocation associated membrane protein 1	endoplasmic reticulum	Cellular component	18555783
TADA2A	6871	transcriptional adaptor 2A	nucleus	Cellular component	8552087
CUL3	8452	cullin 3	stress fiber assembly	Biological process	19782033
NOTCH1	4851	notch 1	calcium ion binding	Molecular function	-
ABT1	29777	activator of basal transcription 1	nucleotide binding	Molecular function	-
OR2M3	127062	olfactory receptor, family 2, subfamily M, member 3	G-protein coupled receptor activity	Molecular function	-
FAT4	79633	FAT atypical cadherin 4	homophilic cell adhesion via plasma membrane adhesion molecules	Biological process	-
MRPL15	29088	mitochondrial ribosomal protein L15	mitochondrial translational initiation	Biological process	-
KMT2D	8085	lysine (K)-specific methyltransferase 2D	histone methyltransferase complex	Cellular component	14992727
ULK1	8408	unc-51 like autophagy activating kinase 1	response to starvation	Biological process	-
MAOB	4129	monoamine oxidase B	positive regulation of dopamine metabolic process	Biological process	-
CSN2	1447	casein beta	calcium ion binding	Molecular function	2387396
SRR	63826	serine racemase	serine racemase activity	Molecular function	11054547
FOXA3	3171	forkhead box A3	spermatogenesis	Biological process	-
FGF16	8823	fibroblast growth factor 16	intracellular	Cellular component	-
WNT16	51384	wingless-type MMTV integration site family, member 16	proteinaceous extracellular matrix	Cellular component	-
PSIP1	11168	PC4 and SFRS1 interacting protein 1	RNA polymerase II transcription coactivator activity	Molecular function	9822615
ELP5	23587	elongator acetyltransferase complex subunit 5	regulation of transcription, DNA-templated	Biological process	-
OR4A16	81327	olfactory receptor, family 4, subfamily A, member 16	integral component of membrane	Cellular component	-
CA1	759	carbonic anhydrase I	protein binding	Molecular function	25416956
TUBB2B	347733	tubulin, beta 2B class IIb	neuron migration	Biological process	19465910
BRCA1	672	breast cancer 1, early onset	regulation of DNA methylation	Biological process	-
GIMAP5	55340	GTPase, IMAP family member 5	regulation of mitochondrial membrane permeability	Biological process	-
RC3H1	149041	ring finger and CCCH-type domains 1	positive regulation of NIK/NF-kappaB signaling	Biological process	-
APC2	10297	adenomatosis polyposis coli 2	negative regulation of canonical Wnt signaling pathway	Biological process	10021369
LTF	4057	lactotransferrin	positive regulation of protein serine/threonine kinase activity	Biological process	20345905
HIPK2	28996	homeodomain interacting protein kinase 2	positive regulation of protein binding	Biological process	-
RAB9B	51209	RAB9B, member RAS oncogene family	intracellular protein transport	Biological process	-
RSPO3	84870	R-spondin 3	frizzled binding	Molecular function	-
GRIA4	2893	glutamate receptor, ionotropic, AMPA 4	synaptic transmission	Biological process	-
THAP6	152815	THAP domain containing 6	DNA binding	Molecular function	-
NKAIN2	154215	Na+/K+ transporting ATPase interacting 2	integral component of membrane	Cellular component	-
RBMS1	5937	RNA binding motif, single stranded interacting protein 1	single-stranded DNA binding	Molecular function	7838710
CRY1	1407	cryptochrome circadian clock 1	DNA repair	Biological process	-
SDCBP	6386	syndecan binding protein (syntenin)	protein C-terminus binding	Molecular function	-
STXBP1	6812	syntaxin binding protein 1	axon target recognition	Biological process	-
MYPN	84665	myopalladin	muscle alpha-actinin binding	Molecular function	11309420
STK39	27347	serine threonine kinase 39	cytoplasm	Cellular component	10980603
GPR61	83873	G protein-coupled receptor 61	G-protein coupled receptor activity	Molecular function	-
HCFC1	3054	host cell factor C1	MLL5-L complex	Cellular component	-
MYLK	4638	myosin light chain kinase	protein binding	Molecular function	17474147
DFNB31	25861	deafness, autosomal recessive 31	stereocilia ankle link complex	Cellular component	-
PPARA	5465	peroxisome proliferator-activated receptor alpha	steroid hormone mediated signaling pathway	Biological process	-
RBMXL1	494115	RNA binding motif protein, X-linked-like 1	mRNA processing	Biological process	-
SAMD9L	219285	sterile alpha motif domain containing 9-like	spleen development	Biological process	-
AKR1A1	10327	aldo-keto reductase family 1, member A1 (aldehyde reductase)	cytosol	Cellular component	-
GCA	25801	grancalcin, EF-hand calcium binding protein	protein binding	Molecular function	25416956
PKP3	11187	plakophilin 3	desmosome	Cellular component	-
PTH	5741	parathyroid hormone	response to cadmium ion	Biological process	-
DOCK9	23348	dedicator of cytokinesis 9	endomembrane system	Cellular component	-
ADAMTS16	170690	ADAM metallopeptidase with thrombospondin type 1 motif, 16	proteolysis	Biological process	-
TNK2	10188	tyrosine kinase, non-receptor, 2	adherens junction	Cellular component	-
ERCC2	2068	excision repair cross-complementation group 2	spindle	Cellular component	20797633
PKD2L2	27039	polycystic kidney disease 2-like 2	detection of mechanical stimulus	Biological process	-
RPH3AL	9501	rabphilin 3A-like (without C2 domains)	LIM domain binding	Molecular function	-
ZNF180	7733	zinc finger protein 180	DNA binding	Molecular function	-
FES	2242	FES proto-oncogene, tyrosine kinase	protein autophosphorylation	Biological process	7687763
ZXDC	79364	ZXD family zinc finger C	positive regulation of transcription, DNA-templated	Biological process	16600381
RAB14	51552	RAB14, member RAS oncogene family	intracellular protein transport	Biological process	-
ANO10	55129	anoctamin 10	membrane	Cellular component	19946888
DYRK2	8445	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2	ribonucleoprotein complex	Cellular component	-
MYH9	4627	myosin, heavy chain 9, non-muscle	negative regulation of actin filament severing	Biological process	-
RAB27B	5874	RAB27B, member RAS oncogene family	extracellular exosome	Cellular component	19199708
VASN	114990	vasorin	negative regulation of epithelial to mesenchymal transition	Biological process	21170088
ERAP2	64167	endoplasmic reticulum aminopeptidase 2	zinc ion binding	Molecular function	12799365
CD9	928	CD9 molecule	external side of plasma membrane	Cellular component	-
MARK1	4139	MAP/microtubule affinity-regulating kinase 1	microtubule cytoskeleton	Cellular component	9108484
SCN9A	6335	sodium channel, voltage gated, type IX alpha subunit	voltage-gated sodium channel activity	Molecular function	-
INTU	27152	inturned planar cell polarity protein	hair follicle morphogenesis	Biological process	-
ADHFE1	137872	alcohol dehydrogenase, iron containing, 1	metal ion binding	Molecular function	-
NDUFAF2	91942	NADH dehydrogenase (ubiquinone) complex I, assembly factor 2	mitochondrion	Cellular component	-
PRKAR2A	5576	protein kinase, cAMP-dependent, regulatory, type II, alpha	membrane	Cellular component	19946888
ATP6V1F	9296	ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F	ATPase activity, coupled to transmembrane movement of ions	Molecular function	-
ENDOU	8909	endonuclease, polyU-specific	immune response	Biological process	-
ARL13B	200894	ADP-ribosylation factor-like 13B	intracellular	Cellular component	-
WDR47	22911	WD repeat domain 47	microtubule	Cellular component	-
HLA-DPA1	3113	major histocompatibility complex, class II, DP alpha 1	ER to Golgi transport vesicle membrane	Cellular component	-
ENTPD1	953	ectonucleoside triphosphate diphosphohydrolase 1	nucleoside-triphosphatase activity	Molecular function	-
OR5K2	402135	olfactory receptor, family 5, subfamily K, member 2	plasma membrane	Cellular component	-
GP1BA	2811	glycoprotein Ib (platelet), alpha polypeptide	thrombin receptor activity	Molecular function	12855810
OR7G3	390883	olfactory receptor, family 7, subfamily G, member 3	G-protein coupled receptor signaling pathway	Biological process	-
GABARAP	11337	GABA(A) receptor-associated protein	protein targeting	Biological process	9892355
TNRC6C	57690	trinucleotide repeat containing 6C	innate immune response	Biological process	-
ARID4A	5926	AT rich interactive domain 4A (RBP1-like)	transcription from RNA polymerase II promoter	Biological process	8414517
TBPL1	9519	TBP-like 1	transcription coactivator activity	Molecular function	10220372
TRA2B	6434	transformer 2 beta homolog (Drosophila)	positive regulation of mRNA splicing, via spliceosome	Biological process	15009664
SLC5A9	200010	solute carrier family 5 (sodium/sugar cotransporter), member 9	transporter activity	Molecular function	-
GPC1	2817	glypican 1	glycosaminoglycan biosynthetic process	Biological process	-
TGFB3	7043	transforming growth factor, beta 3	uterine wall breakdown	Biological process	18039789
PIRT	644139	phosphoinositide-interacting regulator of transient receptor potential channels	integral component of membrane	Cellular component	-
ZC3H8	84524	zinc finger CCCH-type containing 8	negative regulation of transcription, DNA-templated	Biological process	-
CNOT8	9337	CCR4-NOT transcription complex, subunit 8	intracellular	Cellular component	-
TREM1	54210	triggering receptor expressed on myeloid cells 1	activation of mitophagy in response to mitochondrial depolarization	Biological process	22020285
CNTNAP2	26047	contactin associated protein-like 2	axon	Cellular component	-
GPD1L	23171	glycerol-3-phosphate dehydrogenase 1-like	phosphatidic acid biosynthetic process	Biological process	-
KDELR3	11015	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3	integral component of membrane	Cellular component	-
F7	2155	coagulation factor VII (serum prothrombin conversion accelerator)	extracellular region	Cellular component	-
CCRN4L	25819	CCR4 carbon catabolite repression 4-like (S. cerevisiae)	response to extracellular stimulus	Biological process	-
TUBB3	10381	tubulin, beta 3 class III	'de novo' posttranslational protein folding	Biological process	-
PSMA6	5687	proteasome (prosome, macropain) subunit, alpha type, 6	programmed cell death	Biological process	-
RHOBTB3	22836	Rho-related BTB domain containing 3	ATP binding	Molecular function	19490898
MAPK8	5599	mitogen-activated protein kinase 8	apoptotic process	Biological process	-
UGT1A4	54657	UDP glucuronosyltransferase 1 family, polypeptide A4	integral component of membrane	Cellular component	-
FNTB	2342	farnesyltransferase, CAAX box, beta	rhodopsin mediated signaling pathway	Biological process	-
SERPINI1	5274	serpin peptidase inhibitor, clade I (neuroserpin), member 1	extracellular exosome	Cellular component	23376485
RNF2	6045	ring finger protein 2	chromatin binding	Molecular function	25519132
RFX8	731220	RFX family member 8, lacking RFX DNA binding domain	nucleus	Cellular component	-
TARS	6897	threonyl-tRNA synthetase	protein homodimerization activity	Molecular function	2033077
DCAF6	55827	DDB1 and CUL4 associated factor 6	focal adhesion	Cellular component	-
ARTN	9048	artemin	signal transduction	Biological process	9883723
SHH	6469	sonic hedgehog	embryonic limb morphogenesis	Biological process	-
INTS7	25896	integrator complex subunit 7	chromosome	Cellular component	21659603
OR4P4	81300	olfactory receptor, family 4, subfamily P, member 4	transmembrane signaling receptor activity	Molecular function	-
G6PC	2538	glucose-6-phosphatase, catalytic subunit	glycogen metabolic process	Biological process	8211187
ATF7	11016	activating transcription factor 7	regulation of transcription, DNA-templated	Biological process	8288576
BHMT	635	betaine--homocysteine S-methyltransferase	small molecule metabolic process	Biological process	-
LY9	4063	lymphocyte antigen 9	molecular_function	Molecular function	-
LILRB2	10288	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	heterotypic cell-cell adhesion	Biological process	19124746
GNA12	2768	guanine nucleotide binding protein (G protein) alpha 12	GTP binding	Molecular function	-
SP6	80320	Sp6 transcription factor	transcription, DNA-templated	Biological process	-
LOXL4	84171	lysyl oxidase-like 4	protein-lysine 6-oxidase activity	Molecular function	-
MBD1	4152	methyl-CpG binding domain protein 1	transcription from RNA polymerase II promoter	Biological process	9774669
NSUN3	63899	NOP2/Sun domain family, member 3	methyltransferase activity	Molecular function	-
TOMM5	401505	translocase of outer mitochondrial membrane 5 homolog (yeast)	cellular protein metabolic process	Biological process	-
MC2R	4158	melanocortin 2 receptor (adrenocorticotropic hormone)	plasma membrane	Cellular component	-
NET1	10276	neuroepithelial cell transforming 1	cytosol	Cellular component	-
RAB9A	9367	RAB9A, member RAS oncogene family	vacuolar membrane	Cellular component	-
GJA1	2697	gap junction protein, alpha 1, 43kDa	regulation of bicellular tight junction assembly	Biological process	-
TWIST2	117581	twist family bHLH transcription factor 2	sequence-specific DNA binding transcription factor activity	Molecular function	-
OR3A2	4995	olfactory receptor, family 3, subfamily A, member 2	receptor activity	Molecular function	8921386
CYBA	1535	cytochrome b-245, alpha polypeptide	innate immune response	Biological process	2243141
CLECL1	160365	C-type lectin-like 1	plasma membrane	Cellular component	-
ADCY3	109	adenylate cyclase 3	cellular response to glucagon stimulus	Biological process	-
DEFB114	245928	defensin, beta 114	negative regulation of lipopolysaccharide-mediated signaling pathway	Biological process	23482568
PARK2	5071	parkin RBR E3 ubiquitin protein ligase	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	Biological process	21113145
CXXC4	80319	CXXC finger protein 4	cytoplasm	Cellular component	11113207
RAP1A	5906	RAP1A, member of RAS oncogene family	protein transporter activity	Molecular function	17916086
ME2	4200	malic enzyme 2, NAD(+)-dependent, mitochondrial	oxidation-reduction process	Biological process	-
EIF3K	27335	eukaryotic translation initiation factor 3, subunit K	cytoplasm	Cellular component	-
IL12RB2	3595	interleukin 12 receptor, beta 2	positive regulation of cell proliferation	Biological process	8943050
THAP10	56906	THAP domain containing 10	protein binding	Molecular function	21516116
HMGCR	3156	3-hydroxy-3-methylglutaryl-CoA reductase	negative regulation of vasodilation	Biological process	-
PLEKHG2	64857	pleckstrin homology domain containing, family G (with RhoGef domain) member 2	protein binding	Molecular function	25416956
RHEB	6009	Ras homolog enriched in brain	GTP binding	Molecular function	-
TPR	7175	translocated promoter region, nuclear basket protein	carbohydrate metabolic process	Biological process	-
CTNNA1	1495	catenin (cadherin-associated protein), alpha 1, 102kDa	cytosol	Cellular component	-
EIF4G2	1982	eukaryotic translation initiation factor 4 gamma, 2	cytokine-mediated signaling pathway	Biological process	-
STAT5B	6777	signal transducer and activator of transcription 5B	cellular response to hormone stimulus	Biological process	12552091
KCNE3	10008	potassium channel, voltage gated subfamily E regulatory beta subunit 3	regulation of membrane repolarization	Biological process	-
RAP2B	5912	RAP2B, member of RAS oncogene family	positive regulation of protein autophosphorylation	Biological process	-
DYNLL2	140735	dynein, light chain, LC8-type 2	ciliary tip	Cellular component	-
TPCN2	219931	two pore segment channel 2	protein binding	Molecular function	21903581
CDC27	996	cell division cycle 27	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition	Biological process	-
HSPA2	3306	heat shock 70kDa protein 2	unfolded protein binding	Molecular function	21231916
MEF2A	4205	myocyte enhancer factor 2A	MyD88-dependent toll-like receptor signaling pathway	Biological process	-
CNOT6	57472	CCR4-NOT transcription complex, subunit 6	positive regulation of cytoplasmic mRNA processing body assembly	Biological process	21233283
MTMR2	8898	myotubularin related protein 2	negative regulation of receptor catabolic process	Biological process	-
GAS2L1	10634	growth arrest-specific 2 like 1	regulation of cell cycle	Biological process	19375645
ADCY7	113	adenylate cyclase 7	epidermal growth factor receptor signaling pathway	Biological process	-
CTSL	1514	cathepsin L	extracellular space	Cellular component	22952693
SHPK	23729	sedoheptulokinase	cellular response to interleukin-4	Biological process	-
TRIM37	4591	tripartite motif containing 37	tumor necrosis factor receptor binding	Molecular function	11279055
BCHE	590	butyrylcholinesterase	membrane	Cellular component	-
CSTL1	128817	cystatin-like 1	extracellular region	Cellular component	-
OR6N2	81442	olfactory receptor, family 6, subfamily N, member 2	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
FOXI3	344167	forkhead box I3	sequence-specific DNA binding transcription factor activity	Molecular function	-
PSMB9	5698	proteasome (prosome, macropain) subunit, beta type, 9	antigen processing and presentation of peptide antigen via MHC class I	Biological process	-
OR10AG1	282770	olfactory receptor, family 10, subfamily AG, member 1	G-protein coupled receptor activity	Molecular function	-
KIF12	113220	kinesin family member 12	extracellular exosome	Cellular component	19056867
KANK4	163782	KN motif and ankyrin repeat domains 4	cytoplasm	Cellular component	-
PSEN2	5664	presenilin 2	protein complex	Cellular component	9632714
PPM1N	147699	protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)	phosphoprotein phosphatase activity	Molecular function	-
SHH	6469	sonic hedgehog	negative regulation of cell migration	Biological process	-
LOC400927-CSNK1E	102800317	LOC400927-CSNK1E readthrough	protein binding	Molecular function	11425858
GLUD1	2746	glutamate dehydrogenase 1	mitochondrial matrix	Cellular component	-
RMDN3	55177	regulator of microtubule dynamics 3	mitochondrion	Cellular component	-
SPRY2	10253	sprouty homolog 2 (Drosophila)	positive regulation of ERK1 and ERK2 cascade	Biological process	18070883
ADIRF	10974	adipogenesis regulatory factor	molecular_function	Molecular function	-
ST6GALNAC5	81849	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5	protein N-linked glycosylation via asparagine	Biological process	-
SYNM	23336	synemin, intermediate filament protein	costamere	Cellular component	16777071
ACVR1	90	activin A receptor, type I	germ cell development	Biological process	-
HNRNPM	4670	heterogeneous nuclear ribonucleoprotein M	protein binding	Molecular function	18457437
VKORC1L1	154807	vitamin K epoxide reductase complex, subunit 1-like 1	endoplasmic reticulum membrane	Cellular component	21367861
PLK1	5347	polo-like kinase 1	activation of APC-Cdc20 complex activity	Biological process	15148369
NDUFAF1	51103	NADH dehydrogenase (ubiquinone) complex I, assembly factor 1	mitochondrial electron transport, NADH to ubiquinone	Biological process	11935339
CHRNG	1146	cholinergic receptor, nicotinic, gamma (muscle)	transport	Biological process	3967651
BAG5	9529	BCL2-associated athanogene 5	negative regulation of protein ubiquitination	Biological process	15603737
CALM1	801	calmodulin 1 (phosphorylase kinase, delta)	extracellular region	Cellular component	-
PDK3	5165	pyruvate dehydrogenase kinase, isozyme 3	pyruvate metabolic process	Biological process	-
RARG	5916	retinoic acid receptor, gamma	regulation of cell size	Biological process	18438858
FAM83D	81610	family with sequence similarity 83, member D	mitotic nuclear division	Biological process	-
CRHBP	1393	corticotropin releasing hormone binding protein	synaptic transmission, dopaminergic	Biological process	-
SUZ12	23512	SUZ12 polycomb repressive complex 2 subunit	metal ion binding	Molecular function	-
MTDH	92140	metadherin	RNA polymerase II transcription factor binding	Molecular function	18316612
RAB6B	51560	RAB6B, member RAS oncogene family	retrograde transport, endosome to Golgi	Biological process	-
RNF128	79589	ring finger protein 128, E3 ubiquitin protein ligase	zinc ion binding	Molecular function	-
RAC2	5880	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	lymphocyte aggregation	Biological process	21167572
ZNF596	169270	zinc finger protein 596	metal ion binding	Molecular function	-
NDUFC1	4717	NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa	small molecule metabolic process	Biological process	-
GZMH	2999	granzyme H (cathepsin G-like 2, protein h-CCPX)	serine-type endopeptidase activity	Molecular function	2193684
RAPGEF2	9693	Rap guanine nucleotide exchange factor (GEF) 2	cellular response to cGMP	Biological process	10801446
ABCB11	8647	ATP-binding cassette, sub-family B (MDR/TAP), member 11	bile acid and bile salt transport	Biological process	-
FAM168B	130074	family with sequence similarity 168, member B	perinuclear region of cytoplasm	Cellular component	-
PDGFRA	5156	platelet-derived growth factor receptor, alpha polypeptide	luteinization	Biological process	-
PROCR	10544	protein C receptor, endothelial	extracellular exosome	Cellular component	23376485
GNG3	2785	guanine nucleotide binding protein (G protein), gamma 3	signal transducer activity	Molecular function	-
MVB12B	89853	multivesicular body subunit 12B	ubiquitin binding	Molecular function	20654576
SI	6476	sucrase-isomaltase (alpha-glucosidase)	plasma membrane	Cellular component	-
UBE2D2	7322	ubiquitin-conjugating enzyme E2D 2	cytosol	Cellular component	-
ZP4	57829	zona pellucida glycoprotein 4	positive regulation of protein kinase activity	Biological process	18667750
HNRNPDL	9987	heterogeneous nuclear ribonucleoprotein D-like	nucleoplasm	Cellular component	-
QPCT	25797	glutaminyl-peptide cyclotransferase	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase	Biological process	21288892
AP1S2	8905	adaptor-related protein complex 1, sigma 2 subunit	cytosol	Cellular component	-
LRRC29	26231	leucine rich repeat containing 29	protein binding	Molecular function	25416956
CRH	1392	corticotropin releasing hormone	response to ether	Biological process	-
TYMP	1890	thymidine phosphorylase	mitochondrial genome maintenance	Biological process	9924029
AES	166	amino-terminal enhancer of split	multicellular organismal development	Biological process	8365415
ALB	213	albumin	cellular response to starvation	Biological process	16245148
GPR101	83550	G protein-coupled receptor 101	beta-adrenergic receptor activity	Molecular function	-
TLR2	7097	toll-like receptor 2	response to insulin	Biological process	-
TMEM219	124446	transmembrane protein 219	plasma membrane	Cellular component	-
PHIP	55023	pleckstrin homology domain interacting protein	negative regulation of apoptotic process	Biological process	-
ADRBK1	156	adrenergic, beta, receptor kinase 1	fibroblast growth factor receptor signaling pathway	Biological process	-
BCCIP	56647	BRCA2 and CDKN1A interacting protein	kinase regulator activity	Molecular function	10878006
ZNF74	7625	zinc finger protein 74	regulation of transcription, DNA-templated	Biological process	-
ALOX15B	247	arachidonate 15-lipoxygenase, type B	apoptotic process	Biological process	11839751
FBP1	2203	fructose-1,6-bisphosphatase 1	glucose metabolic process	Biological process	-
KIF21A	55605	kinesin family member 21A	metabolic process	Biological process	-
FUS	2521	FUS RNA binding protein	identical protein binding	Molecular function	23975937
PHAX	51808	phosphorylated adaptor for RNA export	gene expression	Biological process	-
CLNK	116449	cytokine-dependent hematopoietic cell linker	protein binding	Molecular function	16273093
SSR3	6747	signal sequence receptor, gamma (translocon-associated protein gamma)	gene expression	Biological process	-
ANTXR1	84168	anthrax toxin receptor 1	lamellipodium membrane	Cellular component	16762926
RPS27A	6233	ribosomal protein S27a	transforming growth factor beta receptor signaling pathway	Biological process	-
UGT1A1	54658	UDP glucuronosyltransferase 1 family, polypeptide A1	steroid metabolic process	Biological process	19996319
CORO1A	11151	coronin, actin binding protein, 1A	membrane	Cellular component	19946888
CCDC106	29903	coiled-coil domain containing 106	nucleoplasm	Cellular component	-
KCNN2	3781	potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2	small conductance calcium-activated potassium channel activity	Molecular function	10991935
RASGRP2	10235	RAS guanyl releasing protein 2 (calcium and DAG-regulated)	Ras protein signal transduction	Biological process	10918068
PKM	5315	pyruvate kinase, muscle	magnesium ion binding	Molecular function	-
CTNNBL1	56259	catenin, beta like 1	nucleus	Cellular component	12659813
PRKCQ	5588	protein kinase C, theta	plasma membrane	Cellular component	-
SCAF8	22828	SR-related CTD-associated factor 8	RNA binding	Molecular function	-
NOS3	4846	nitric oxide synthase 3 (endothelial cell)	endocytic vesicle membrane	Cellular component	-
CTSB	1508	cathepsin B	melanosome	Cellular component	-
RGPD3	653489	RANBP2-like and GRIP domain containing 3	protein targeting to Golgi	Biological process	-
PCSK1	5122	proprotein convertase subtilisin/kexin type 1	regulation of insulin secretion	Biological process	-
ARSE	415	arylsulfatase E (chondrodysplasia punctata 1)	sphingolipid metabolic process	Biological process	-
AZU1	566	azurocidin 1	cytoplasm	Cellular component	-
LRP4	4038	low density lipoprotein receptor-related protein 4	extracellular matrix organization	Biological process	-
MED15	51586	mediator complex subunit 15	regulation of transcription from RNA polymerase II promoter	Biological process	-
TLR2	7097	toll-like receptor 2	positive regulation of inflammatory response	Biological process	19740627
ZNF354C	30832	zinc finger protein 354C	nuclear membrane	Cellular component	-
RAB3B	5865	RAB3B, member RAS oncogene family	protein secretion	Biological process	-
RNF4	6047	ring finger protein 4	protein K48-linked ubiquitination	Biological process	-
AKR1C4	1109	aldo-keto reductase family 1, member C4	oxidation-reduction process	Biological process	-
C21orf59	56683	chromosome 21 open reading frame 59	cytosol	Cellular component	16780588
B4GALT1	2683	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	acute inflammatory response	Biological process	-
KLC2	64837	kinesin light chain 2	kinesin I complex	Cellular component	20510358
PPAP2A	8611	phosphatidic acid phosphatase type 2A	phospholipid dephosphorylation	Biological process	9468526
GNRH2	2797	gonadotropin-releasing hormone 2	extracellular region	Cellular component	-
PIGP	51227	phosphatidylinositol glycan anchor biosynthesis, class P	integral component of membrane	Cellular component	-
NDFIP2	54602	Nedd4 family interacting protein 2	negative regulation of gene expression	Biological process	18776082
NDRG3	57446	NDRG family member 3	negative regulation of cell growth	Biological process	11406283
NF1	4763	neurofibromin 1	negative regulation of cell migration	Biological process	16648142
LOXL1	4016	lysyl oxidase-like 1	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	Molecular function	-
CASP3	836	caspase 3, apoptosis-related cysteine peptidase	extracellular matrix disassembly	Biological process	-
OVCA2	124641	ovarian tumor suppressor candidate 2	metabolic process	Biological process	11979432
VPS11	55823	vacuolar protein sorting 11 homolog (S. cerevisiae)	nucleotide binding	Molecular function	-
UPP2	151531	uridine phosphorylase 2	small molecule metabolic process	Biological process	-
SNX30	401548	sorting nexin family member 30	protein binding	Molecular function	23085988
VCAM1	7412	vascular cell adhesion molecule 1	viral process	Biological process	-
IGF1	3479	insulin-like growth factor 1 (somatomedin C)	platelet degranulation	Biological process	-
MET	4233	MET proto-oncogene, receptor tyrosine kinase	signal transduction	Biological process	1846706
BCL2L11	10018	BCL2-like 11 (apoptosis facilitator)	ear development	Biological process	-
ACP5	54	acid phosphatase 5, tartrate resistant	riboflavin metabolic process	Biological process	-
TRABD2A	129293	TraB domain containing 2A	head development	Biological process	-
VPS35	55737	vacuolar protein sorting 35 homolog (S. cerevisiae)	retromer complex	Cellular component	-
CDH5	1003	cadherin 5, type 2 (vascular endothelium)	calcium ion binding	Molecular function	-
FSD1	79187	fibronectin type III and SPRY domain containing 1	cell division	Biological process	-
IBTK	25998	inhibitor of Bruton agammaglobulinemia tyrosine kinase	negative regulation of protein phosphorylation	Biological process	11577348
CEBPZ	10153	CCAAT/enhancer binding protein (C/EBP), zeta	poly(A) RNA binding	Molecular function	22658674
TRAF6	7189	TNF receptor-associated factor 6, E3 ubiquitin protein ligase	positive regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	-
FLT4	2324	fms-related tyrosine kinase 4	sprouting angiogenesis	Biological process	-
MICAL2	9645	microtubule associated monooxygenase, calponin and LIM domain containing 2	heart looping	Biological process	-
ETV3	2117	ets variant 3	regulation of transcription from RNA polymerase II promoter	Biological process	-
RBFOX2	23543	RNA binding protein, fox-1 homolog (C. elegans) 2	radial glia guided migration of Purkinje cell	Biological process	-
MRPL44	65080	mitochondrial ribosomal protein L44	RNA processing	Biological process	-
SIX2	10736	SIX homeobox 2	kidney development	Biological process	-
FBXO4	26272	F-box protein 4	cytoplasm	Cellular component	-
FOS	2353	FBJ murine osteosarcoma viral oncogene homolog	transcription factor binding	Molecular function	10523647
ARHGAP5	394	Rho GTPase activating protein 5	SH2 domain binding	Molecular function	1689011
GNAT2	2780	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2	photoreceptor outer segment membrane	Cellular component	-
CHRNA4	1137	cholinergic receptor, nicotinic, alpha 4 (neuronal)	respiratory gaseous exchange	Biological process	-
YES1	7525	YES proto-oncogene 1, Src family tyrosine kinase	protein binding	Molecular function	15657067
OR10X1	128367	olfactory receptor, family 10, subfamily X, member 1 (gene/pseudogene)	olfactory receptor activity	Molecular function	-
MECP2	4204	methyl CpG binding protein 2	long-term synaptic potentiation	Biological process	-
CDK18	5129	cyclin-dependent kinase 18	protein phosphorylation	Biological process	-
CHP1	11261	calcineurin-like EF-hand protein 1	negative regulation of protein autophosphorylation	Biological process	-
RPL14	9045	ribosomal protein L14	translation	Biological process	-
TRIM43	129868	tripartite motif containing 43	protein binding	Molecular function	25416956
PRSS16	10279	protease, serine, 16 (thymus)	cytoplasmic membrane-bounded vesicle	Cellular component	-
ABHD1	84696	abhydrolase domain containing 1	carboxylic ester hydrolase activity	Molecular function	-
HSP90AB4P	664618	heat shock protein 90kDa alpha (cytosolic), class B member 4, pseudogene	response to stress	Biological process	-
SMIM24	284422	small integral membrane protein 24	biological_process	Biological process	-
B4GALNT2	124872	beta-1,4-N-acetyl-galactosaminyl transferase 2	protein glycosylation	Biological process	-
STYX	6815	serine/threonine/tyrosine interacting protein	protein binding	Molecular function	23847209
RPLP2	6181	ribosomal protein, large, P2	extracellular exosome	Cellular component	20458337
STX2	2054	syntaxin 2	basolateral plasma membrane	Cellular component	16339081
MMRN2	79812	multimerin 2	negative regulation of vascular endothelial growth factor receptor signaling pathway	Biological process	22020326
OR1L4	254973	olfactory receptor, family 1, subfamily L, member 4	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
SYNE1	23345	spectrin repeat containing, nuclear envelope 1	nucleoplasm	Cellular component	-
SMN2	6607	survival of motor neuron 2, centromeric	nucleus	Cellular component	11283611
RGL2	5863	ral guanine nucleotide dissociation stimulator-like 2	Ral guanyl-nucleotide exchange factor activity	Molecular function	-
ABCA7	10347	ATP-binding cassette, sub-family A (ABC1), member 7	endosome membrane	Cellular component	-
LMAN2L	81562	lectin, mannose-binding 2-like	protein transport	Biological process	12878160
UBASH3A	53347	ubiquitin associated and SH3 domain containing A	negative regulation of T cell receptor signaling pathway	Biological process	-
VDR	7421	vitamin D (1,25- dihydroxyvitamin D3) receptor	lithocholic acid receptor activity	Molecular function	12016314
MYBL1	4603	v-myb avian myeloblastosis viral oncogene homolog-like 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	7987850
FAM53B	9679	family with sequence similarity 53, member B	molecular_function	Molecular function	-
CNR1	1268	cannabinoid receptor 1 (brain)	negative regulation of nitric-oxide synthase activity	Biological process	-
CALCOCO2	10241	calcium binding and coiled-coil domain 2	Golgi apparatus	Cellular component	-
ANGPT4	51378	angiopoietin 4	positive regulation of blood vessel endothelial cell migration	Biological process	15284220
HS3ST5	222537	heparan sulfate (glucosamine) 3-O-sulfotransferase 5	heparan sulfate proteoglycan biosynthetic process, enzymatic modification	Biological process	12138164
UGP2	7360	UDP-glucose pyrophosphorylase 2	UDP-glucose metabolic process	Biological process	-
KIFC2	90990	kinesin family member C2	cytoplasm	Cellular component	-
RHOU	58480	ras homolog family member U	positive regulation of protein targeting to mitochondrion	Biological process	24270810
PPP1R13L	10848	protein phosphatase 1, regulatory subunit 13 like	intercellular bridge	Cellular component	-
AZGP1	563	alpha-2-glycoprotein 1, zinc-binding	immune response	Biological process	-
NFS1	9054	NFS1 cysteine desulfurase	metal ion binding	Molecular function	-
TCTN2	79867	tectonic family member 2	cilium assembly	Biological process	-
WDR61	80349	WD repeat domain 61	Cdc73/Paf1 complex	Cellular component	20178742
GPC1	2817	glypican 1	anchored component of membrane	Cellular component	-
SEC23IP	11196	SEC23 interacting protein	intracellular membrane-bounded organelle	Cellular component	-
TRDMT1	1787	tRNA aspartic acid methyltransferase 1	tRNA methyltransferase activity	Molecular function	16424344
NRXN1	9378	neurexin 1	vocalization behavior	Biological process	17034946
OR11H1	81061	olfactory receptor, family 11, subfamily H, member 1	G-protein coupled receptor signaling pathway	Biological process	-
BLMH	642	bleomycin hydrolase	carboxypeptidase activity	Molecular function	9546396
CCL5	6352	chemokine (C-C motif) ligand 5	cellular calcium ion homeostasis	Biological process	10734056
PGM3	5238	phosphoglucomutase 3	cytosol	Cellular component	-
NTRK3	4916	neurotrophic tyrosine kinase, receptor, type 3	positive regulation of actin cytoskeleton reorganization	Biological process	23027130
KIAA1109	84162	KIAA1109	protein binding	Molecular function	20195357
CAD	790	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	small molecule metabolic process	Biological process	-
WNT4	54361	wingless-type MMTV integration site family, member 4	negative regulation of gene expression	Biological process	15317892
ARHGAP19	84986	Rho GTPase activating protein 19	small GTPase mediated signal transduction	Biological process	-
SPTBN5	51332	spectrin, beta, non-erythrocytic 5	Golgi organization	Biological process	23704327
PLEC	5339	plectin	cytosol	Cellular component	-
FGF4	2249	fibroblast growth factor 4	positive regulation of cell proliferation	Biological process	8663044
MAN2A1	4124	mannosidase, alpha, class 2A, member 1	mitochondrion organization	Biological process	-
RUNX2	860	runt-related transcription factor 2	endochondral ossification	Biological process	-
SERP1	27230	stress-associated endoplasmic reticulum protein 1	cellular protein metabolic process	Biological process	-
TPI1	7167	triosephosphate isomerase 1	ubiquitin protein ligase binding	Molecular function	19725078
IGHD	3495	immunoglobulin heavy constant delta	extracellular exosome	Cellular component	23533145
SLC30A7	148867	solute carrier family 30 (zinc transporter), member 7	sequestering of zinc ion	Biological process	-
DUSP9	1852	dual specificity phosphatase 9	cytoplasm	Cellular component	-
HMGA2	8091	high mobility group AT-hook 2	negative regulation by host of viral transcription	Biological process	17005673
CYP1A2	1544	cytochrome P450, family 1, subfamily A, polypeptide 2	intracellular membrane-bounded organelle	Cellular component	2813353
RRAS2	22800	related RAS viral (r-ras) oncogene homolog 2	metabolic process	Biological process	10777492
C4B	721	complement component 4B (Chido blood group)	positive regulation of apoptotic cell clearance	Biological process	19302245
ARPC5	10092	actin related protein 2/3 complex, subunit 5, 16kDa	extracellular exosome	Cellular component	19056867
TMEM108	66000	transmembrane protein 108	integral component of membrane	Cellular component	-
HTR6	3362	5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled	serotonin receptor activity	Molecular function	-
UBE2D1	7321	ubiquitin-conjugating enzyme E2D 1	mitotic spindle assembly checkpoint	Biological process	-
NOS3	4846	nitric oxide synthase 3 (endothelial cell)	mitochondrion organization	Biological process	-
GDF3	9573	growth differentiation factor 3	notochord development	Biological process	-
PRPH	5630	peripherin	intermediate filament cytoskeleton organization	Biological process	-
ENPP1	5167	ectonucleotide pyrophosphatase/phosphodiesterase 1	protein homodimerization activity	Molecular function	7830796
ADM	133	adrenomedullin	response to hypoxia	Biological process	-
FFAR1	2864	free fatty acid receptor 1	G-protein coupled receptor activity	Molecular function	9344866
GP2	2813	glycoprotein 2 (zymogen granule membrane)	antigen binding	Molecular function	-
POU4F2	5458	POU class 4 homeobox 2	chromatin binding	Molecular function	-
GNA12	2768	guanine nucleotide binding protein (G protein) alpha 12	heterotrimeric G-protein complex	Cellular component	-
PEX14	5195	peroxisomal biogenesis factor 14	integral component of membrane	Cellular component	-
PLSCR1	5359	phospholipid scramblase 1	phospholipid scramblase activity	Molecular function	10770950
ACE	1636	angiotensin I converting enzyme	actin binding	Molecular function	16186248
GABBR2	9568	gamma-aminobutyric acid (GABA) B receptor, 2	plasma membrane	Cellular component	-
PTGIS	5740	prostaglandin I2 (prostacyclin) synthase	icosanoid metabolic process	Biological process	-
ADAR	103	adenosine deaminase, RNA-specific	adenosine to inosine editing	Biological process	-
ASF1B	55723	anti-silencing function 1B histone chaperone	spermatogenesis	Biological process	-
AQP1	358	aquaporin 1 (Colton blood group)	protein binding	Molecular function	16189514
CDCA8	55143	cell division cycle associated 8	nucleus	Cellular component	-
ARNT	405	aryl hydrocarbon receptor nuclear translocator	protein heterodimerization activity	Molecular function	9079689
BNIP3	664	BCL2/adenovirus E1B 19kDa interacting protein 3	response to hypoxia	Biological process	-
ZFP36L1	677	ZFP36 ring finger protein-like 1	regulation of transcription, DNA-templated	Biological process	8595910
BSCL2	26580	Berardinelli-Seip congenital lipodystrophy 2 (seipin)	lipid storage	Biological process	19278620
TSC2	7249	tuberous sclerosis 2	protein transport into plasma membrane raft	Biological process	-
TH	7054	tyrosine hydroxylase	response to lipopolysaccharide	Biological process	-
SERGEF	26297	secretion regulating guanine nucleotide exchange factor	Ran guanyl-nucleotide exchange factor activity	Molecular function	10571079
ALDH18A1	5832	aldehyde dehydrogenase 18 family, member A1	glutamate 5-kinase activity	Molecular function	11092761
RBMS1	5937	RNA binding motif, single stranded interacting protein 1	nucleotide binding	Molecular function	-
ABHD2	11057	abhydrolase domain containing 2	metabolic process	Biological process	-
OR52Z1	283110	olfactory receptor, family 52, subfamily Z, member 1 (gene/pseudogene)	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
USP6	9098	ubiquitin specific peptidase 6	calmodulin binding	Molecular function	16127172
COL4A2	1284	collagen, type IV, alpha 2	extracellular region	Cellular component	-
VAMP7	6845	vesicle-associated membrane protein 7	cell surface	Cellular component	-
GATA4	2626	GATA binding protein 4	positive regulation of cardiac muscle cell proliferation	Biological process	-
CXADR	1525	coxsackie virus and adenovirus receptor	leukocyte migration	Biological process	-
AGRN	375790	agrin	neurotransmitter receptor metabolic process	Biological process	-
AATK	9625	apoptosis-associated tyrosine kinase	protein serine/threonine kinase activity	Molecular function	-
APOA1	335	apolipoprotein A-I	cholesterol homeostasis	Biological process	15464323
PDPK1	5170	3-phosphoinositide dependent protein kinase 1	cytoplasmic membrane-bounded vesicle	Cellular component	-
WFS1	7466	Wolfram syndrome 1 (wolframin)	positive regulation of proteolysis	Biological process	-
PDE11A	50940	phosphodiesterase 11A	cGMP binding	Molecular function	19689430
BOP1	23246	block of proliferation 1	preribosome, large subunit precursor	Cellular component	-
ABCA6	23460	ATP-binding cassette, sub-family A (ABC1), member 6	ATPase activity, coupled to transmembrane movement of substances	Molecular function	-
LGSN	51557	lengsin, lens protein with glutamine synthetase domain	plasma membrane	Cellular component	-
RNF141	50862	ring finger protein 141	ubiquitin-protein transferase activity	Molecular function	24105792
SLC7A6	9057	solute carrier family 7 (amino acid transporter light chain, y+L system), member 6	transport	Biological process	9829974
CNIH4	29097	cornichon family AMPA receptor auxiliary protein 4	CCR5 chemokine receptor binding	Molecular function	24405750
IL17A	3605	interleukin 17A	cell death	Biological process	8390535
PRDX1	5052	peroxiredoxin 1	peroxisomal matrix	Cellular component	-
MICB	4277	MHC class I polypeptide-related sequence B	immune response-activating cell surface receptor signaling pathway	Biological process	11491531
PDCD11	22984	programmed cell death 11	cytosol	Cellular component	-
CMTM7	112616	CKLF-like MARVEL transmembrane domain containing 7	chemotaxis	Biological process	-
PIN1	5300	peptidylprolyl cis/trans isomerase, NIMA-interacting 1	regulation of mitotic nuclear division	Biological process	10391244
CXCL10	3627	chemokine (C-X-C motif) ligand 10	CXCR3 chemokine receptor binding	Molecular function	12782716
TGIF1	7050	TGFB-induced factor homeobox 1	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
BMP7	655	bone morphogenetic protein 7	positive regulation of pathway-restricted SMAD protein phosphorylation	Biological process	11580864
ADGRV1	84059	adhesion G protein-coupled receptor V1	G-protein coupled receptor signaling pathway	Biological process	-
ITGB4	3691	integrin, beta 4	filopodium assembly	Biological process	-
ZDHHC3	51304	zinc finger, DHHC-type containing 3	protein targeting	Biological process	-
FUBP1	8880	far upstream element (FUSE) binding protein 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
RUNX1	861	runt-related transcription factor 1	protein homodimerization activity	Molecular function	10856244
GSK3B	2932	glycogen synthase kinase 3 beta	cell migration	Biological process	-
DST	667	dystonin	focal adhesion	Cellular component	21423176
TBX3	6926	T-box 3	negative regulation of myoblast differentiation	Biological process	12032820
SREBF2	6721	sterol regulatory element binding transcription factor 2	E-box binding	Molecular function	15358760
GNAL	2774	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type	extracellular exosome	Cellular component	23533145
ACVR1B	91	activin A receptor, type IB	metal ion binding	Molecular function	-
CACNA1C	775	calcium channel, voltage-dependent, L type, alpha 1C subunit	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	Biological process	11576544
CTNNA1	1495	catenin (cadherin-associated protein), alpha 1, 102kDa	vascular endothelial growth factor receptor signaling pathway	Biological process	-
FOLH1B	219595	folate hydrolase 1B	proteolysis	Biological process	-
HRH2	3274	histamine receptor H2	memory	Biological process	-
SLC28A3	64078	solute carrier family 28 (concentrative nucleoside transporter), member 3	pyrimidine- and adenine-specific:sodium symporter activity	Molecular function	-
NFIC	4782	nuclear factor I/C (CCAAT-binding transcription factor)	odontogenesis of dentin-containing tooth	Biological process	-
XRCC6	2547	X-ray repair complementing defective repair in Chinese hamster cells 6	double-strand break repair	Biological process	-
LCK	3932	LCK proto-oncogene, Src family tyrosine kinase	CD8 receptor binding	Molecular function	2470098
RIPK1	8737	receptor (TNFRSF)-interacting serine-threonine kinase 1	positive regulation of type I interferon production	Biological process	-
APOH	350	apolipoprotein H (beta-2-glycoprotein I)	extracellular matrix	Cellular component	20551380
MRPL18	29074	mitochondrial ribosomal protein L18	mitochondrial translational termination	Biological process	-
PPP6R3	55291	protein phosphatase 6, regulatory subunit 3	plasma membrane	Cellular component	-
NR3C1	2908	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	adrenal gland development	Biological process	-
RPS6KA1	6195	ribosomal protein S6 kinase, 90kDa, polypeptide 1	toll-like receptor 2 signaling pathway	Biological process	-
GORAB	92344	golgin, RAB6-interacting	Golgi apparatus	Cellular component	-
TSG101	7251	tumor susceptibility 101	late endosome	Cellular component	15126635
TENM3	55714	teneurin transmembrane protein 3	protein heterodimerization activity	Molecular function	-
ZMAT3	64393	zinc finger, matrin-type 3	cellular response to DNA damage stimulus	Biological process	-
DEPDC7	91614	DEP domain containing 7	molecular_function	Molecular function	-
TRDMT1	1787	tRNA aspartic acid methyltransferase 1	tRNA methylation	Biological process	16424344
MED20	9477	mediator complex subunit 20	DNA-directed RNA polymerase activity	Molecular function	9933582
ATG101	60673	autophagy related 101	protein binding	Molecular function	20562859
MYLK3	91807	myosin light chain kinase 3	calmodulin-dependent protein kinase activity	Molecular function	-
TWIST1	7291	twist family bHLH transcription factor 1	nucleus	Cellular component	10749989
GK2	2712	glycerol kinase 2	mitochondrial outer membrane	Cellular component	-
IFNA13	3447	interferon, alpha 13	type I interferon signaling pathway	Biological process	-
AGTPBP1	23287	ATP/GTP binding protein 1	protein side chain deglutamylation	Biological process	-
FER1L4	80307	fer-1-like family member 4, pseudogene (functional)	integral component of membrane	Cellular component	-
IL23R	149233	interleukin 23 receptor	positive regulation of granulocyte macrophage colony-stimulating factor production	Biological process	20027291
PHKG1	5260	phosphorylase kinase, gamma 1 (muscle)	glycogen biosynthetic process	Biological process	-
ZYX	7791	zyxin	plasma membrane	Cellular component	8940160
WRAP53	55135	WD repeat containing, antisense to TP53	nucleus	Cellular component	-
MARK2	2011	MAP/microtubule affinity-regulating kinase 2	protein autophosphorylation	Biological process	-
PAQR8	85315	progestin and adipoQ receptor family member VIII	response to steroid hormone	Biological process	-
CA5BP1	340591	carbonic anhydrase VB pseudogene 1	carbonate dehydratase activity	Molecular function	-
PNPO	55163	pyridoxamine 5'-phosphate oxidase	cytoplasm	Cellular component	-
BCAM	4059	basal cell adhesion molecule (Lutheran blood group)	cell adhesion	Biological process	7954395
SIX3	6496	SIX homeobox 3	transcription coactivator activity	Molecular function	-
C4BPB	725	complement component 4 binding protein, beta	negative regulation of complement activation, classical pathway	Biological process	22333221
ATP6V0D2	245972	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2	phagosome maturation	Biological process	-
MUC5B	727897	mucin 5B, oligomeric mucus/gel-forming	defense response to bacterium	Biological process	-
TBX21	30009	T-box 21	sequence-specific DNA binding transcription factor activity	Molecular function	10761931
TWF1	5756	twinfilin actin-binding protein 1	phosphatidylinositol-4,5-bisphosphate binding	Molecular function	12807912
EDRF1	26098	erythroid differentiation regulatory factor 1	regulation of transcription, DNA-templated	Biological process	-
RAB27B	5874	RAB27B, member RAS oncogene family	protein domain specific binding	Molecular function	16880209
RBL1	5933	retinoblastoma-like 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
TPR	7175	translocated promoter region, nuclear basket protein	protein anchor	Molecular function	12802065
ENG	2022	endoglin	negative regulation of transforming growth factor beta receptor signaling pathway	Biological process	11382917
GNAI2	2771	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	G-protein beta/gamma-subunit complex binding	Molecular function	-
BAD	572	BCL2-associated agonist of cell death	cellular response to lipid	Biological process	-
RXRA	6256	retinoid X receptor, alpha	regulation of branching involved in prostate gland morphogenesis	Biological process	-
OR2A25	392138	olfactory receptor, family 2, subfamily A, member 25	olfactory receptor activity	Molecular function	-
CHMP3	51652	charged multivesicular body protein 3	membrane organization	Biological process	-
TMSB10	9168	thymosin beta 10	protein binding	Molecular function	25416956
CTGF	1490	connective tissue growth factor	cell-cell signaling	Biological process	-
MYO6	4646	myosin VI	motor activity	Molecular function	-
NAT2	10	N-acetyltransferase 2 (arylamine N-acetyltransferase)	arylamine N-acetyltransferase activity	Molecular function	-
OR51Q1	390061	olfactory receptor, family 51, subfamily Q, member 1 (gene/pseudogene)	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
SLC6A5	9152	solute carrier family 6 (neurotransmitter transporter), member 5	neurotransmitter:sodium symporter activity	Molecular function	-
ICE2	79664	interactor of little elongation complex ELL subunit 2	transcriptionally active chromatin	Cellular component	22195968
COL1A2	1278	collagen, type I, alpha 2	extracellular matrix organization	Biological process	-
CD19	930	CD19 molecule	epidermal growth factor receptor signaling pathway	Biological process	-
A1BG	1	alpha-1-B glycoprotein	extracellular exosome	Cellular component	19056867
PTPN2	5771	protein tyrosine phosphatase, non-receptor type 2	regulation of interferon-gamma-mediated signaling pathway	Biological process	-
STK11	6794	serine/threonine kinase 11	positive regulation of axonogenesis	Biological process	-
LIPC	3990	lipase, hepatic	high-density lipoprotein particle remodeling	Biological process	3244012
ATP6V0A2	23545	ATPase, H+ transporting, lysosomal V0 subunit a2	ion transmembrane transport	Biological process	-
SGK2	10110	serum/glucocorticoid regulated kinase 2	ion transmembrane transport	Biological process	-
MKNK2	2872	MAP kinase interacting serine/threonine kinase 2	cellular response to arsenic-containing substance	Biological process	18299328
PDE6A	5145	phosphodiesterase 6A, cGMP-specific, rod, alpha	phototransduction, visible light	Biological process	-
EXT1	2131	exostosin glycosyltransferase 1	olfactory bulb development	Biological process	-
FCHO2	115548	FCH domain only 2	phosphatidylserine binding	Molecular function	-
YTHDC2	64848	YTH domain containing 2	ATP-dependent RNA helicase activity	Molecular function	-
XRCC2	7516	X-ray repair complementing defective repair in Chinese hamster cells 2	strand invasion	Biological process	11834724
CAPZA3	93661	capping protein (actin filament) muscle Z-line, alpha 3	F-actin capping protein complex	Cellular component	-
SOCS7	30837	suppressor of cytokine signaling 7	protein binding	Molecular function	17803907
SLC6A17	388662	solute carrier family 6 (neutral amino acid transporter), member 17	neutral amino acid transport	Biological process	-
ZNF570	148268	zinc finger protein 570	metal ion binding	Molecular function	-
ABCB6	10058	ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)	endoplasmic reticulum	Cellular component	22226084
RANBP10	57610	RAN binding protein 10	microtubule cytoskeleton organization	Biological process	-
DCAF7	10238	DDB1 and CUL4 associated factor 7	cytoplasm	Cellular component	9192870
CHMP4B	128866	charged multivesicular body protein 4B	late endosome membrane	Cellular component	-
UNK	85451	unkempt family zinc finger	negative regulation of cytoplasmic translation	Biological process	25737280
RSPO2	340419	R-spondin 2	positive regulation of canonical Wnt signaling pathway	Biological process	-
AARS	16	alanyl-tRNA synthetase	negative regulation of neuron apoptotic process	Biological process	-
ALG6	29929	ALG6, alpha-1,3-glucosyltransferase	endoplasmic reticulum membrane	Cellular component	-
NUFIP1	26747	nuclear fragile X mental retardation protein interacting protein 1	pre-snoRNP complex	Cellular component	17636026
GAS1	2619	growth arrest-specific 1	programmed cell death	Biological process	-
SLC9A1	6548	solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1	protein oligomerization	Biological process	-
CGN	57530	cingulin	biological_process	Biological process	-
NCOR1	9611	nuclear receptor corepressor 1	cytoplasm	Cellular component	-
AIF1	199	allograft inflammatory factor 1	positive regulation of monocyte chemotaxis	Biological process	15117732
POLR2M	81488	polymerase (RNA) II (DNA directed) polypeptide M	neuronal cell body	Cellular component	-
TRAK1	22906	trafficking protein, kinesin binding 1	mitochondrion	Cellular component	15644324
ISL1	3670	ISL LIM homeobox 1	trigeminal nerve development	Biological process	-
MGST3	4259	microsomal glutathione S-transferase 3	intracellular membrane-bounded organelle	Cellular component	9278457
NF1	4763	neurofibromin 1	intrinsic component of the cytoplasmic side of the plasma membrane	Cellular component	-
GJA1	2697	gap junction protein, alpha 1, 43kDa	skeletal muscle tissue regeneration	Biological process	-
SESN1	27244	sestrin 1	cell cycle arrest	Biological process	9926927
IFNG	3458	interferon, gamma	positive regulation of fructose 1,6-bisphosphate metabolic process	Biological process	9282826
FUT8	2530	fucosyltransferase 8 (alpha (1,6) fucosyltransferase)	integrin-mediated signaling pathway	Biological process	-
DNAJA3	9093	DnaJ (Hsp40) homolog, subfamily A, member 3	negative regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	11927590
NUP98	4928	nucleoporin 98kDa	nucleocytoplasmic transport	Biological process	9348540
RBM5	10181	RNA binding motif protein 5	nucleoplasm	Cellular component	-
SPDL1	54908	spindle apparatus coiled-coil protein 1	protein localization to kinetochore	Biological process	19468067
DMRT3	58524	doublesex and mab-3 related transcription factor 3	protein heterodimerization activity	Molecular function	-
PGAP2	27315	post-GPI attachment to proteins 2	endoplasmic reticulum membrane	Cellular component	-
PURG	29942	purine-rich element binding protein G	poly(A) RNA binding	Molecular function	22681889
CPB1	1360	carboxypeptidase B1 (tissue)	metallocarboxypeptidase activity	Molecular function	-
ITGAL	3683	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	plasma membrane	Cellular component	-
BET1L	51272	Bet1 golgi vesicular membrane trafficking protein-like	Golgi apparatus	Cellular component	15215310
PARK2	5071	parkin RBR E3 ubiquitin protein ligase	identical protein binding	Molecular function	21694720
SMARCA5	8467	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	condensed chromosome	Cellular component	12972596
PCDHB15	56121	protocadherin beta 15	calcium ion binding	Molecular function	-
STX12	23673	syntaxin 12	Golgi membrane	Cellular component	-
TKFC	26007	triokinase/FMN cyclase	regulation of innate immune response	Biological process	16289032
DNASE2	1777	deoxyribonuclease II, lysosomal	deoxyribonuclease II activity	Molecular function	-
KDM1B	221656	lysine (K)-specific demethylase 1B	transcription, DNA-templated	Biological process	-
PIK3CD	5293	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	T cell activation	Biological process	20940048
XCL1	6375	chemokine (C motif) ligand 1	negative regulation of transcription, DNA-templated	Biological process	10887101
SYT4	6860	synaptotagmin IV	neuron projection	Cellular component	-
LHX5	64211	LIM homeobox 5	sequence-specific DNA binding	Molecular function	-
BTBD2	55643	BTB (POZ) domain containing 2	cytoplasmic mRNA processing body	Cellular component	12878161
MAP2K4	6416	mitogen-activated protein kinase kinase 4	mitogen-activated protein kinase kinase kinase binding	Molecular function	-
CCL16	6360	chemokine (C-C motif) ligand 16	immune response	Biological process	-
PLK1	5347	polo-like kinase 1	protein serine/threonine kinase activity	Molecular function	19473992
C2CD4D	100191040	C2 calcium-dependent domain containing 4D	syntaxin binding	Molecular function	-
ATP1A2	477	ATPase, Na+/K+ transporting, alpha 2 polypeptide	metabolic process	Biological process	-
VCAM1	7412	vascular cell adhesion molecule 1	chronic inflammatory response	Biological process	-
TTR	7276	transthyretin	retinoid metabolic process	Biological process	-
CHUK	1147	conserved helix-loop-helix ubiquitous kinase	toll-like receptor 9 signaling pathway	Biological process	-
THBS1	7057	thrombospondin 1	cellular response to tumor necrosis factor	Biological process	-
CDK5RAP3	80279	CDK5 regulatory subunit associated protein 3	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
PKP1	5317	plakophilin 1	lamin binding	Molecular function	10852826
GSPT2	23708	G1 to S phase transition 2	cell cycle	Biological process	-
HIF3A	64344	hypoxia inducible factor 3, alpha subunit	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
UBQLN2	29978	ubiquilin 2	regulation of macroautophagy	Biological process	20529957
HIST1H4A	8359	histone cluster 1, H4a	histone binding	Molecular function	20498094
SST	6750	somatostatin	response to heat	Biological process	-
GTF3C4	9329	general transcription factor IIIC, polypeptide 4, 90kDa	histone acetyltransferase activity	Molecular function	-
LYRM1	57149	LYR motif containing 1	mitochondrion	Cellular component	-
CHST9	83539	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9	sulfur compound metabolic process	Biological process	11445554
ABTB1	80325	ankyrin repeat and BTB (POZ) domain containing 1	nucleolus	Cellular component	-
PDK4	5166	pyruvate dehydrogenase kinase, isozyme 4	reactive oxygen species metabolic process	Biological process	21852536
PTS	5805	6-pyruvoyltetrahydropterin synthase	protein binding	Molecular function	25416956
CD5	921	CD5 molecule	T cell costimulation	Biological process	-
MAP9	79884	microtubule-associated protein 9	regulation of mitotic nuclear division	Biological process	-
PLK2	10769	polo-like kinase 2	centrosome	Cellular component	15242618
ALG9	79796	ALG9, alpha-1,2-mannosyltransferase	endoplasmic reticulum membrane	Cellular component	-
APOA1	335	apolipoprotein A-I	chemorepellent activity	Molecular function	23726972
ABCA7	10347	ATP-binding cassette, sub-family A (ABC1), member 7	apolipoprotein A-I receptor activity	Molecular function	14570867
PLAUR	5329	plasminogen activator, urokinase receptor	receptor activity	Molecular function	1689240
HOXA1	3198	homeobox A1	anatomical structure morphogenesis	Biological process	16155570
ITPR3	3710	inositol 1,4,5-trisphosphate receptor, type 3	brush border	Cellular component	8288584
BMP2	650	bone morphogenetic protein 2	SMAD binding	Molecular function	18184661
ESRRG	2104	estrogen-related receptor gamma	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
TSSK1B	83942	testis-specific serine kinase 1B	intracellular signal transduction	Biological process	-
POLA1	5422	polymerase (DNA directed), alpha 1, catalytic subunit	DNA binding	Molecular function	3359994
CREB3	10488	cAMP responsive element binding protein 3	integral component of endoplasmic reticulum membrane	Cellular component	20546900
AGO3	192669	argonaute RISC catalytic component 3	mRNA cleavage involved in gene silencing by siRNA	Biological process	15260970
NCF4	4689	neutrophil cytosolic factor 4, 40kDa	phagolysosome	Cellular component	-
PTEN	5728	phosphatase and tensin homolog	central nervous system development	Biological process	-
CEP131	22994	centrosomal protein 131kDa	intercellular bridge	Cellular component	-
SLC1A5	6510	solute carrier family 1 (neutral amino acid transporter), member 5	integral component of plasma membrane	Cellular component	8702519
APAF1	317	apoptotic peptidase activating factor 1	cytosol	Cellular component	-
CA14	23632	carbonic anhydrase XIV	small molecule metabolic process	Biological process	-
YWHAE	7531	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon	membrane	Cellular component	19946888
OR5AL1	79482	olfactory receptor, family 5, subfamily AL, member 1 (gene/pseudogene)	G-protein coupled receptor activity	Molecular function	-
FGFR2	2263	fibroblast growth factor receptor 2	positive regulation of epithelial cell proliferation involved in lung morphogenesis	Biological process	-
RFTN1	23180	raftlin, lipid raft linker 1	B cell receptor signaling pathway	Biological process	12805216
TAAR3	9288	trace amine associated receptor 3 (gene/pseudogene)	integral component of membrane	Cellular component	-
INSL3	3640	insulin-like 3 (Leydig cell)	in utero embryonic development	Biological process	-
ELN	2006	elastin	cell proliferation	Biological process	9607766
CGNL1	84952	cingulin-like 1	metabolic process	Biological process	-
GATA3	2625	GATA binding protein 3	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
ALKBH2	121642	alkB, alkylation repair homolog 2 (E. coli)	cytosine C-5 DNA demethylase activity	Molecular function	18775698
HBB	3043	hemoglobin, beta	receptor-mediated endocytosis	Biological process	-
TRAP1	10131	TNF receptor-associated protein 1	chaperone-mediated protein folding	Biological process	24522549
CTDP1	9150	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1	spindle pole	Cellular component	22692537
TXNL1	9352	thioredoxin-like 1	glycerol ether metabolic process	Biological process	-
IRAK2	3656	interleukin-1 receptor-associated kinase 2	protein heterodimerization activity	Molecular function	10383454
CD74	972	CD74 molecule, major histocompatibility complex, class II invariant chain	extracellular exosome	Cellular component	20458337
PRDM7	11105	PR domain containing 7	chromosome	Cellular component	-
GSC	145258	goosecoid homeobox	transcription factor complex	Cellular component	-
RPTOR	57521	regulatory associated protein of MTOR, complex 1	RNA polymerase III type 2 promoter DNA binding	Molecular function	20233713
TIMD4	91937	T-cell immunoglobulin and mucin domain containing 4	integral component of membrane	Cellular component	-
FAM3A	60343	family with sequence similarity 3, member A	biological_process	Biological process	-
CELF4	56853	CUGBP, Elav-like family member 4	germ cell development	Biological process	10893231
CHD5	26038	chromodomain helicase DNA binding protein 5	transcription from RNA polymerase II promoter	Biological process	-
CACNB2	783	calcium channel, voltage-dependent, beta 2 subunit	neuromuscular junction development	Biological process	8494331
SCAMP2	10066	secretory carrier membrane protein 2	nucleoplasm	Cellular component	-
FAT4	79633	FAT atypical cadherin 4	plasma membrane	Cellular component	-
DOPEY2	9980	dopey family member 2	Golgi to endosome transport	Biological process	16301316
RSU1	6251	Ras suppressor protein 1	focal adhesion	Cellular component	20926685
WNT1	7471	wingless-type MMTV integration site family, member 1	positive regulation of protein phosphorylation	Biological process	-
MME	4311	membrane metallo-endopeptidase	plasma membrane	Cellular component	-
LTBP1	4052	latent transforming growth factor beta binding protein 1	transmembrane receptor protein serine/threonine kinase signaling pathway	Biological process	8537398
RBFOX3	146713	RNA binding protein, fox-1 homolog (C. elegans) 3	DNA binding	Molecular function	-
RRAGD	58528	Ras-related GTP binding D	lysosome	Cellular component	20381137
SEC22C	9117	SEC22 vesicle trafficking protein homolog C (S. cerevisiae)	SNARE binding	Molecular function	-
IRS2	8660	insulin receptor substrate 2	innate immune response	Biological process	-
SHH	6469	sonic hedgehog	formation of anatomical boundary	Biological process	-
UBXN1	51035	UBX domain protein 1	dendrite	Cellular component	-
SLC34A1	6569	solute carrier family 34 (type II sodium/phosphate cotransporter), member 1	brush border membrane	Cellular component	8693007
RAB3A	5864	RAB3A, member RAS oncogene family	protein binding	Molecular function	10859313
DAB2IP	153090	DAB2 interacting protein	parallel fiber	Cellular component	-
EGR1	1958	early growth response 1	learning or memory	Biological process	-
HTRA2	27429	HtrA serine peptidase 2	membrane	Cellular component	24798695
TUBB	203068	tubulin, beta class I	cell body	Cellular component	19567321
KCNH8	131096	potassium channel, voltage gated eag related subfamily H, member 8	regulation of ion transmembrane transport	Biological process	-
PDGFRB	5159	platelet-derived growth factor receptor, beta polypeptide	platelet-derived growth factor receptor-beta signaling pathway	Biological process	2554309
LYNX1	66004	Ly6/neurotoxin 1	anchored component of membrane	Cellular component	-
GABARAPL2	11345	GABA(A) receptor-associated protein-like 2	negative regulation of proteasomal protein catabolic process	Biological process	21669198
CXCR3	2833	chemokine (C-X-C motif) receptor 3	cell adhesion	Biological process	10942362
GPER1	2852	G protein-coupled estrogen receptor 1	apoptotic chromosome condensation	Biological process	-
PURA	5813	purine-rich element binding protein A	neuronal cell body	Cellular component	-
SUV39H1	6839	suppressor of variegation 3-9 homolog 1 (Drosophila)	cellular response to DNA damage stimulus	Biological process	23509280
FHIT	2272	fragile histidine triad	nucleotide binding	Molecular function	-
YES1	7525	YES proto-oncogene 1, Src family tyrosine kinase	epidermal growth factor receptor binding	Molecular function	-
ATP5B	506	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide	ATP hydrolysis coupled proton transport	Biological process	-
CLDN19	149461	claudin 19	neuronal action potential propagation	Biological process	-
MOB1B	92597	MOB kinase activator 1B	kinase binding	Molecular function	15197186
OR2A12	346525	olfactory receptor, family 2, subfamily A, member 12	sensory perception of smell	Biological process	-
NUP88	4927	nucleoporin 88kDa	cellular protein metabolic process	Biological process	-
CASP8	841	caspase 8, apoptosis-related cysteine peptidase	toll-like receptor 3 signaling pathway	Biological process	-
EP400	57634	E1A binding protein p400	nucleoplasm	Cellular component	-
BMP3	651	bone morphogenetic protein 3	cartilage development	Biological process	-
ALDH1A3	220	aldehyde dehydrogenase 1 family, member A3	cytoplasm	Cellular component	11585737
NAP1L4	4676	nucleosome assembly protein 1-like 4	nucleus	Cellular component	-
BRINP1	1620	bone morphogenetic protein/retinoic acid inducible neural-specific 1	cytoplasm	Cellular component	11420708
LSM10	84967	LSM10, U7 small nuclear RNA associated	histone pre-mRNA DCP binding	Molecular function	-
ZNRF1	84937	zinc and ring finger 1, E3 ubiquitin protein ligase	protein binding	Molecular function	19549727
POLR1A	25885	polymerase (RNA) I polypeptide A, 194kDa	DNA binding	Molecular function	-
RPF2	84154	ribosome production factor 2 homolog (S. cerevisiae)	nucleus	Cellular component	-
PITPNB	23760	phosphatidylinositol transfer protein, beta	Golgi membrane	Cellular component	-
MITF	4286	microphthalmia-associated transcription factor	positive regulation of transcription, DNA-templated	Biological process	10578055
RFX3	5991	regulatory factor X, 3 (influences HLA class II expression)	nuclear chromatin	Cellular component	20413507
OR10AC1	392133	olfactory receptor, family 10, subfamily AC, member 1 (gene/pseudogene)	olfactory receptor activity	Molecular function	-
THY1	7070	Thy-1 cell surface antigen	focal adhesion assembly	Biological process	-
GBF1	8729	golgi brefeldin A resistant guanine nucleotide exchange factor 1	phosphatidylinositol-3,5-bisphosphate binding	Molecular function	22573891
ESYT2	57488	extended synaptotagmin-like protein 2	endoplasmic reticulum	Cellular component	-
TXK	7294	TXK tyrosine kinase	transcription, DNA-templated	Biological process	-
LST1	7940	leukocyte specific transcript 1	Golgi apparatus	Cellular component	11478849
ASIC1	41	acid sensing (proton gated) ion channel 1	integral component of plasma membrane	Cellular component	-
KCNN3	3782	potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3	neuronal cell body	Cellular component	-
H1F0	3005	H1 histone family, member 0	chromatin DNA binding	Molecular function	15911621
ITGA6	3655	integrin, alpha 6	basal plasma membrane	Cellular component	-
NSL1	25936	NSL1, MIS12 kinetochore complex component	mitotic cell cycle	Biological process	-
IFITM3	10410	interferon induced transmembrane protein 3	plasma membrane	Cellular component	-
DPEP3	64180	dipeptidase 3	dipeptidyl-peptidase activity	Molecular function	-
RPSA	3921	ribosomal protein SA	viral transcription	Biological process	-
HIST1H4B	8366	histone cluster 1, H4b	nucleus	Cellular component	14585971
GIMAP1	170575	GTPase, IMAP family member 1	Golgi membrane	Cellular component	-
CDH15	1013	cadherin 15, type 1, M-cadherin (myotubule)	extracellular exosome	Cellular component	23533145
EGR1	1958	early growth response 1	cellular response to growth factor stimulus	Biological process	-
HP1BP3	50809	heterochromatin protein 1, binding protein 3	cellular response to hypoxia	Biological process	25100860
CALR	811	calreticulin	receptor-mediated endocytosis	Biological process	-
PROC	5624	protein C (inactivator of coagulation factors Va and VIIIa)	endoplasmic reticulum lumen	Cellular component	-
HOXB5	3215	homeobox B5	protein binding	Molecular function	25416956
FHOD3	80206	formin homology 2 domain containing 3	cardiac myofibril assembly	Biological process	-
CNOT7	29883	CCR4-NOT transcription complex, subunit 7	protein binding	Molecular function	11136725
SYNGAP1	8831	synaptic Ras GTPase activating protein 1	Ras protein signal transduction	Biological process	-
TCAP	8557	titin-cap	protein binding, bridging	Molecular function	15582318
POU3F1	5453	POU class 3 homeobox 1	transcription, DNA-templated	Biological process	-
TIMP4	7079	TIMP metallopeptidase inhibitor 4	extracellular space	Cellular component	-
CYP1B1	1545	cytochrome P450, family 1, subfamily B, polypeptide 1	mitochondrion	Cellular component	-
MBD4	8930	methyl-CpG binding domain protein 4	depyrimidination	Biological process	-
GAS6	2621	growth arrest-specific 6	cell cycle arrest	Biological process	16564713
SNX4	8723	sorting nexin 4	early endosome membrane	Cellular component	17994011
CDC42	998	cell division cycle 42	GTPase activity	Molecular function	11035016
EIF2S2	8894	eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa	in utero embryonic development	Biological process	-
SLC23A2	9962	solute carrier family 23 (ascorbic acid transporter), member 2	sodium ion transport	Biological process	-
CLN3	1201	ceroid-lipofuscinosis, neuronal 3	Golgi stack	Cellular component	15240864
ZNF79	7633	zinc finger protein 79	protein binding	Molecular function	25416956
ATP6V1A	523	ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A	ATP binding	Molecular function	-
MEF2A	4205	myocyte enhancer factor 2A	cytoplasm	Cellular component	-
GSS	2937	glutathione synthetase	glycine binding	Molecular function	-
PIGL	9487	phosphatidylinositol glycan anchor biosynthesis, class L	C-terminal protein lipidation	Biological process	-
PTCH1	5727	patched 1	keratinocyte proliferation	Biological process	-
ADPRM	56985	ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent	ADP-ribose diphosphatase activity	Molecular function	-
EP300	2033	E1A binding protein p300	pre-mRNA intronic binding	Molecular function	-
CALR	811	calreticulin	positive regulation of DNA replication	Biological process	14726956
AGTR2	186	angiotensin II receptor, type 2	cellular response to dexamethasone stimulus	Biological process	-
GRM2	2912	glutamate receptor, metabotropic 2	synaptic transmission	Biological process	7620613
NCMAP	400746	noncompact myelin associated protein	peripheral nervous system myelin formation	Biological process	-
LSM8	51691	LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae)	poly(A) RNA binding	Molecular function	22658674
RPP30	10556	ribonuclease P/MRP 30kDa subunit	protein binding	Molecular function	25416956
WAC	51322	WW domain containing adaptor with coiled-coil	positive regulation of macroautophagy	Biological process	22354037
RAG2	5897	recombination activating gene 2	phosphatidylinositol-4,5-bisphosphate binding	Molecular function	-
PLCH2	9651	phospholipase C, eta 2	cellular_component	Cellular component	-
IFT20	90410	intraflagellar transport 20	regulation of autophagosome assembly	Biological process	-
ANKRD36BP1	84832	ankyrin repeat domain 36B pseudogene 1	protein binding	Molecular function	16189514
CIRBP	1153	cold inducible RNA binding protein	response to UV	Biological process	11574538
DNASE2B	58511	deoxyribonuclease II beta	lysosome	Cellular component	-
LIMCH1	22998	LIM and calponin homology domains 1	zinc ion binding	Molecular function	-
SRPX	8406	sushi-repeat containing protein, X-linked	cell surface	Cellular component	-
SLC25A12	8604	solute carrier family 25 (aspartate/glutamate carrier), member 12	gluconeogenesis	Biological process	-
ID2	3398	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	negative regulation of oligodendrocyte differentiation	Biological process	-
HFE	3077	hemochromatosis	protein binding	Molecular function	10638746
PARM1	25849	prostate androgen-regulated mucin-like protein 1	positive regulation of telomerase activity	Biological process	-
FAS	355	Fas cell surface death receptor	extrinsic apoptotic signaling pathway via death domain receptors	Biological process	-
KDELR1	10945	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1	intracellular protein transport	Biological process	2172835
IL2	3558	interleukin 2	regulation of T cell homeostatic proliferation	Biological process	-
PAX1	5075	paired box 1	somitogenesis	Biological process	-
ZNF30	90075	zinc finger protein 30	sequence-specific DNA binding transcription factor activity	Molecular function	-
NCBP1	4686	nuclear cap binding protein subunit 1, 80kDa	transcription from RNA polymerase II promoter	Biological process	-
MBD4	8930	methyl-CpG binding domain protein 4	response to radiation	Biological process	-
TAF1L	138474	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like	regulation of transcription from RNA polymerase II promoter	Biological process	12217962
KIF14	9928	kinesin family member 14	PDZ domain binding	Molecular function	23209302
MKKS	8195	McKusick-Kaufman syndrome	cerebral cortex development	Biological process	-
CATSPER2	117155	cation channel, sperm associated 2	multicellular organismal development	Biological process	-
SIGLEC11	114132	sialic acid binding Ig-like lectin 11	cell adhesion	Biological process	-
SULT4A1	25830	sulfotransferase family 4A, member 1	xenobiotic metabolic process	Biological process	-
GLP2R	9340	glucagon-like peptide 2 receptor	G-protein coupled receptor activity	Molecular function	9990065
DYRK3	8444	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3	nucleus	Cellular component	10779429
NFAT5	10725	nuclear factor of activated T-cells 5, tonicity-responsive	cytoplasm	Cellular component	-
MAP2K2	5605	mitogen-activated protein kinase kinase 2	small GTPase mediated signal transduction	Biological process	-
MMP20	9313	matrix metallopeptidase 20	extracellular region	Cellular component	-
GPR89A	653519	G protein-coupled receptor 89A	voltage-gated anion channel activity	Molecular function	18794847
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	lung induction	Biological process	-
H6PD	9563	hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)	pentose-phosphate shunt	Biological process	-
C1QTNF9B-AS1	542767	C1QTNF9B antisense RNA 1	cytoplasm	Cellular component	-
MUC12	10071	mucin 12, cell surface associated	integral component of plasma membrane	Cellular component	10463611
ANPEP	290	alanyl (membrane) aminopeptidase	metallopeptidase activity	Molecular function	-
SLC25A22	79751	solute carrier family 25 (mitochondrial carrier: glutamate), member 22	L-glutamate transmembrane transporter activity	Molecular function	11897791
SEC63	11231	SEC63 homolog (S. cerevisiae)	IRE1-mediated unfolded protein response	Biological process	-
STAT3	6774	signal transducer and activator of transcription 3 (acute-phase response factor)	signal transducer activity	Molecular function	-
ITGAL	3683	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	ICAM-3 receptor activity	Molecular function	19029120
PPP1R12C	54776	protein phosphatase 1, regulatory subunit 12C	protein binding	Molecular function	21988832
PPARGC1A	10891	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	chromatin DNA binding	Molecular function	-
LPAR1	1902	lysophosphatidic acid receptor 1	lysophosphatidic acid receptor activity	Molecular function	-
UXT	8409	ubiquitously-expressed, prefoldin-like chaperone	chromatin binding	Molecular function	21730289
FOS	2353	FBJ murine osteosarcoma viral oncogene homolog	nucleoplasm	Cellular component	-
INSL4	3641	insulin-like 4 (placenta)	signal transduction	Biological process	8702754
TAX1BP3	30851	Tax1 (human T-cell leukemia virus type I) binding protein 3	extracellular exosome	Cellular component	19056867
SERPINF2	5345	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2	positive regulation of smooth muscle cell proliferation	Biological process	-
PAK6	56924	p21 protein (Cdc42/Rac)-activated kinase 6	Rac GTPase binding	Molecular function	-
COL11A2	1302	collagen, type XI, alpha 2	endoplasmic reticulum lumen	Cellular component	-
SPR	6697	sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)	dopamine metabolic process	Biological process	-
NLGN3	54413	neuroligin 3	positive regulation of synaptic transmission, glutamatergic	Biological process	-
PTRF	284119	polymerase I and transcript release factor	protein complex	Cellular component	24013648
IRX4	50805	iroquois homeobox 4	heart development	Biological process	-
TAPBP	6892	TAP binding protein (tapasin)	amide transport	Biological process	9238042
AQP5	362	aquaporin 5	basal plasma membrane	Cellular component	-
CPSF3L	54973	cleavage and polyadenylation specific factor 3-like	cytoplasm	Cellular component	-
IGF2R	3482	insulin-like growth factor 2 receptor	focal adhesion	Cellular component	21423176
MMP1	4312	matrix metallopeptidase 1	viral process	Biological process	-
CINP	51550	cyclin-dependent kinase 2 interacting protein	nucleus	Cellular component	-
UBE2B	7320	ubiquitin-conjugating enzyme E2B	sperm axoneme assembly	Biological process	-
FCGR3B	2215	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)	immune response	Biological process	2139735
ACLY	47	ATP citrate lyase	small molecule metabolic process	Biological process	-
MYO1B	4430	myosin IB	extracellular exosome	Cellular component	19056867
EFNB1	1947	ephrin-B1	positive regulation of T cell proliferation	Biological process	-
LACTB	114294	lactamase, beta	hydrolase activity	Molecular function	-
LSM3	27258	LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)	mRNA splicing, via spliceosome	Biological process	11991638
ZNF469	84627	zinc finger protein 469	DNA binding	Molecular function	-
ZNF284	342909	zinc finger protein 284	nucleus	Cellular component	-
NUP35	129401	nucleoporin 35kDa	regulation of glucose transport	Biological process	-
NODAL	4838	nodal growth differentiation factor	left lung morphogenesis	Biological process	-
ARL8A	127829	ADP-ribosylation factor-like 8A	GTPase activity	Molecular function	15331635
B4GALT6	9331	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6	galactosyltransferase activity	Molecular function	9597550
TOM1L1	10040	target of myb1 (chicken)-like 1	endosome membrane	Cellular component	-
TNFRSF1B	7133	tumor necrosis factor receptor superfamily, member 1B	tumor necrosis factor-mediated signaling pathway	Biological process	8702885
PPIH	10465	peptidylprolyl isomerase H (cyclophilin H)	protein folding	Biological process	-
STAB2	55576	stabilin 2	regulation of gene expression	Biological process	21810271
ABCB11	8647	ATP-binding cassette, sub-family B (MDR/TAP), member 11	ATP binding	Molecular function	-
CPEB3	22849	cytoplasmic polyadenylation element binding protein 3	apical dendrite	Cellular component	-
RARRES2	5919	retinoic acid receptor responder (tazarotene induced) 2	positive regulation of chemotaxis	Biological process	-
SFRP2	6423	secreted frizzled-related protein 2	positive regulation of cell growth	Biological process	10980594
PRKRA	8575	protein kinase, interferon-inducible double stranded RNA dependent activator	cytoplasm	Cellular component	-
FOXC1	2296	forkhead box C1	transcription from RNA polymerase II promoter	Biological process	-
NANOS2	339345	nanos homolog 2 (Drosophila)	perinuclear region of cytoplasm	Cellular component	19168545
PDXK	8566	pyridoxal (pyridoxine, vitamin B6) kinase	zinc ion binding	Molecular function	10987144
ERCC3	2071	excision repair cross-complementation group 3	ATPase activity	Molecular function	17466626
OR10H4	126541	olfactory receptor, family 10, subfamily H, member 4	integral component of membrane	Cellular component	-
AAMDC	28971	adipogenesis associated, Mth938 domain containing	positive regulation of fat cell differentiation	Biological process	-
SNRPD3	6634	small nuclear ribonucleoprotein D3 polypeptide 18kDa	poly(A) RNA binding	Molecular function	22681889
LRRK2	120892	leucine-rich repeat kinase 2	actin binding	Molecular function	21307259
HEXIM2	124790	hexamethylene bis-acetamide inducible 2	negative regulation of transcription from RNA polymerase II promoter	Biological process	15713662
ARRB1	408	arrestin, beta 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	16325578
MEN1	4221	multiple endocrine neoplasia I	cell cycle arrest	Biological process	-
SUN2	25777	Sad1 and UNC84 domain containing 2	positive regulation of cell migration	Biological process	-
FOXA2	3170	forkhead box A2	cell differentiation in hindbrain	Biological process	-
GAS6	2621	growth arrest-specific 6	signal transduction	Biological process	16564713
PMEL	6490	premelanosome protein	melanin biosynthetic process	Biological process	-
ARHGEF1	9138	Rho guanine nucleotide exchange factor (GEF) 1	negative regulation of axonogenesis	Biological process	-
PRKAR2A	5576	protein kinase, cAMP-dependent, regulatory, type II, alpha	regulation of insulin secretion	Biological process	-
GPER1	2852	G protein-coupled estrogen receptor 1	positive regulation of gene expression	Biological process	-
PRDX3	10935	peroxiredoxin 3	cellular response to oxidative stress	Biological process	21850687
CEL	1056	carboxyl ester lipase	lipid digestion	Biological process	-
ZSCAN30	100101467	zinc finger and SCAN domain containing 30	nucleus	Cellular component	-
ASNS	440	asparagine synthetase (glutamine-hydrolyzing)	response to toxic substance	Biological process	-
SH2D2A	9047	SH2 domain containing 2A	vascular endothelial growth factor receptor signaling pathway	Biological process	-
PHF5A	84844	PHD finger protein 5A	RNA splicing	Biological process	-
SDR16C5	195814	short chain dehydrogenase/reductase family 16C, member 5	retinol metabolic process	Biological process	-
AHR	196	aryl hydrocarbon receptor	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
OPTN	10133	optineurin	identical protein binding	Molecular function	23414517
S100A12	6283	S100 calcium binding protein A12	cytosol	Cellular component	18443896
CATSPERD	257062	catsper channel auxiliary subunit delta	sperm principal piece	Cellular component	-
UQCRH	7388	ubiquinol-cytochrome c reductase hinge protein	small molecule metabolic process	Biological process	-
SYT10	341359	synaptotagmin X	calcium-dependent phospholipid binding	Molecular function	-
SMAD5	4090	SMAD family member 5	bone development	Biological process	-
BLOC1S5	63915	biogenesis of lysosomal organelles complex-1, subunit 5, muted	melanosome organization	Biological process	22203680
SYNJ1	8867	synaptojanin 1	phosphatidylinositol phosphate 5-phosphatase activity	Molecular function	-
SYCP1	6847	synaptonemal complex protein 1	male germ cell nucleus	Cellular component	-
FASN	2194	fatty acid synthase	myristoyl-[acyl-carrier-protein] hydrolase activity	Molecular function	-
ADCY6	112	adenylate cyclase 6	metal ion binding	Molecular function	-
IREB2	3658	iron-responsive element binding protein 2	cytoplasm	Cellular component	7983023
PIP5K1C	23396	phosphatidylinositol-4-phosphate 5-kinase, type I, gamma	synaptic vesicle exocytosis	Biological process	19889969
PPM1B	5495	protein phosphatase, Mg2+/Mn2+ dependent, 1B	negative regulation of defense response to virus	Biological process	22750291
BMP4	652	bone morphogenetic protein 4	odontogenesis	Biological process	11023873
MAPK3	5595	mitogen-activated protein kinase 3	insulin receptor signaling pathway	Biological process	-
RUNX1T1	862	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	metal ion binding	Molecular function	-
SLC9A3	6550	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3	plasma membrane	Cellular component	-
OR7G2	390882	olfactory receptor, family 7, subfamily G, member 2	olfactory receptor activity	Molecular function	-
MAN2C1	4123	mannosidase, alpha, class 2C, member 1	carbohydrate binding	Molecular function	-
COLEC12	81035	collectin sub-family member 12	receptor-mediated endocytosis	Biological process	-
NRXN1	9378	neurexin 1	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	Biological process	-
CHMP4B	128866	charged multivesicular body protein 4B	viral life cycle	Biological process	-
PPP2R1A	5518	protein phosphatase 2, regulatory subunit A, alpha	nucleus	Cellular component	11007961
CRYGA	1418	crystallin, gamma A	lens development in camera-type eye	Biological process	-
SPATA31A6	389730	SPATA31 subfamily A, member 6	cell differentiation	Biological process	-
RAB3C	115827	RAB3C, member RAS oncogene family	myosin V binding	Molecular function	24006491
MC1R	4157	melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)	positive regulation of protein kinase C signaling	Biological process	18292087
HES6	55502	hes family bHLH transcription factor 6	sequence-specific DNA binding transcription factor activity	Molecular function	-
SPATA25	128497	spermatogenesis associated 25	cell differentiation	Biological process	-
LHCGR	3973	luteinizing hormone/choriogonadotropin receptor	adenylate cyclase-activating G-protein coupled receptor signaling pathway	Biological process	-
BBS12	166379	Bardet-Biedl syndrome 12	intraciliary transport	Biological process	-
HLA-A	3105	major histocompatibility complex, class I, A	integral component of plasma membrane	Cellular component	6609814
EGLN1	54583	egl-9 family hypoxia-inducible factor 1	negative regulation of cyclic-nucleotide phosphodiesterase activity	Biological process	-
GLRX2	51022	glutaredoxin 2	cell redox homeostasis	Biological process	11397793
IL23R	149233	interleukin 23 receptor	interleukin-23 receptor complex	Cellular component	12023369
HLA-DRB3	3125	major histocompatibility complex, class II, DR beta 3	clathrin-coated endocytic vesicle membrane	Cellular component	-
KHDC1	80759	KH homology domain containing 1	integral component of membrane	Cellular component	-
HMBS	3145	hydroxymethylbilane synthase	heme biosynthetic process	Biological process	-
MTBP	27085	MDM2 binding protein	protein localization to kinetochore	Biological process	21274008
GRIN2A	2903	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	plasma membrane	Cellular component	-
USF1	7391	upstream transcription factor 1	nucleoplasm	Cellular component	-
TNFRSF19	55504	tumor necrosis factor receptor superfamily, member 19	apoptotic process	Biological process	10809768
ARHGAP21	57584	Rho GTPase activating protein 21	cytoskeleton	Cellular component	-
SIGMAR1	10280	sigma non-opioid intracellular receptor 1	growth cone	Cellular component	-
COX15	1355	cytochrome c oxidase assembly homolog 15 (yeast)	mitochondrial inner membrane	Cellular component	-
FER	2241	fer (fps/fes related) tyrosine kinase	platelet-derived growth factor receptor signaling pathway	Biological process	11994747
HNRNPD	3184	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	protein binding	Molecular function	12107167
LEO1	123169	Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	negative regulation of myeloid cell differentiation	Biological process	20541477
MPDU1	9526	mannose-P-dolichol utilization defect 1	extracellular exosome	Cellular component	23376485
ZBTB7A	51341	zinc finger and BTB domain containing 7A	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
TRAPPC6A	79090	trafficking protein particle complex 6A	Golgi apparatus	Cellular component	-
AMBRA1	55626	autophagy/beclin-1 regulator 1	autophagosome	Cellular component	-
PID1	55022	phosphotyrosine interaction domain containing 1	positive regulation of reactive oxygen species metabolic process	Biological process	20165904
ABCA11P	79963	ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene	ATP binding	Molecular function	-
GPD1L	23171	glycerol-3-phosphate dehydrogenase 1-like	positive regulation of sodium ion transport	Biological process	17967977
GTF2H4	2968	general transcription factor IIH, polypeptide 4, 52kDa	holo TFIIH complex	Cellular component	9852112
NUDT3	11165	nudix (nucleoside diphosphate linked moiety X)-type motif 3	diphosphoinositol-polyphosphate diphosphatase activity	Molecular function	10585413
DPYSL3	1809	dihydropyrimidinase-like 3	actin crosslink formation	Biological process	-
HSPA1A	3303	heat shock 70kDa protein 1A	enzyme binding	Molecular function	23921388
EMP3	2014	epithelial membrane protein 3	cell death	Biological process	12107182
KIF25	3834	kinesin family member 25	microtubule motor activity	Molecular function	-
LAMP5	24141	lysosomal-associated membrane protein family, member 5	endoplasmic reticulum-Golgi intermediate compartment membrane	Cellular component	21642595
SLC35D2	11046	solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2	pyrimidine nucleotide-sugar transmembrane transporter activity	Molecular function	-
RAPGEF3	10411	Rap guanine nucleotide exchange factor (GEF) 3	membrane	Cellular component	10777494
EPHB1	2047	EPH receptor B1	protein autophosphorylation	Biological process	18034775
CNR1	1268	cannabinoid receptor 1 (brain)	response to nutrient	Biological process	-
TSPEAR	54084	thrombospondin-type laminin G domain and EAR repeats	cell surface	Cellular component	-
OSGEP	55644	O-sialoglycoprotein endopeptidase	transferase activity, transferring acyl groups	Molecular function	-
KIF26B	55083	kinesin family member 26B	microtubule-based movement	Biological process	-
DRAM2	128338	DNA-damage regulated autophagy modulator 2	integral component of membrane	Cellular component	-
PPP1R21	129285	protein phosphatase 1, regulatory subunit 21	membrane	Cellular component	19946888
ARL17B	100506084	ADP-ribosylation factor-like 17B	vesicle-mediated transport	Biological process	-
TUBB2A	7280	tubulin, beta 2A class IIa	extracellular exosome	Cellular component	19056867
INHBA	3624	inhibin, beta A	hair follicle development	Biological process	10932194
TRAM2	9697	translocation associated membrane protein 2	protein transport	Biological process	-
UNC13C	440279	unc-13 homolog C (C. elegans)	exocytosis	Biological process	-
YIPF5	81555	Yip1 domain family, member 5	ER to Golgi transport vesicle	Cellular component	-
AGMO	392636	alkylglycerol monooxygenase	oxidation-reduction process	Biological process	-
CSF2RB	1439	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	protein binding	Molecular function	1495999
ZNF567	163081	zinc finger protein 567	metal ion binding	Molecular function	-
HMGN5	79366	high mobility group nucleosome binding domain 5	regulation of transcription from RNA polymerase II promoter	Biological process	-
VIL1	7429	villin 1	positive regulation of lamellipodium morphogenesis	Biological process	18054784
GCK	2645	glucokinase (hexokinase 4)	positive regulation of glycogen biosynthetic process	Biological process	8878425
APC	324	adenomatous polyposis coli	cytoplasmic microtubule organization	Biological process	-
CRY1	1407	cryptochrome circadian clock 1	transcription factor binding transcription factor activity	Molecular function	15147242
MYLPF	29895	myosin light chain, phosphorylatable, fast skeletal muscle	structural constituent of muscle	Molecular function	-
UQCR11	10975	ubiquinol-cytochrome c reductase, complex III subunit XI	mitochondrial inner membrane	Cellular component	-
CGNL1	84952	cingulin-like 1	motor activity	Molecular function	-
PDE5A	8654	phosphodiesterase 5A, cGMP-specific	metal ion binding	Molecular function	-
MRPS23	51649	mitochondrial ribosomal protein S23	ribosome	Cellular component	-
TRAPPC2	6399	trafficking protein particle complex 2	regulation of transcription, DNA-templated	Biological process	11134351
TMX3	54495	thioredoxin-related transmembrane protein 3	response to endoplasmic reticulum stress	Biological process	-
EXOSC4	54512	exosome component 4	cytoplasmic exosome (RNase complex)	Cellular component	-
MAPK4	5596	mitogen-activated protein kinase 4	protein binding	Molecular function	22939624
NCKAP1L	3071	NCK-associated protein 1-like	positive regulation of CD8-positive, alpha-beta T cell differentiation	Biological process	-
A4GNT	51146	alpha-1,4-N-acetylglucosaminyltransferase	Golgi membrane	Cellular component	-
CD86	942	CD86 molecule	response to interferon-gamma	Biological process	-
ZNF511	118472	zinc finger protein 511	regulation of transcription, DNA-templated	Biological process	-
SYT17	51760	synaptotagmin XVII	calcium-dependent phospholipid binding	Molecular function	-
TET2	54790	tet methylcytosine dioxygenase 2	positive regulation of transcription from RNA polymerase II promoter	Biological process	23222540
THEMIS2	9473	thymocyte selection associated family member 2	cell adhesion	Biological process	9563507
MDM2	4193	MDM2 proto-oncogene, E3 ubiquitin protein ligase	response to morphine	Biological process	-
F11	2160	coagulation factor XI	positive regulation of fibrinolysis	Biological process	89876
PICALM	8301	phosphatidylinositol binding clathrin assembly protein	iron ion homeostasis	Biological process	22952941
MYOD1	4654	myogenic differentiation 1	nuclear chromatin	Cellular component	-
CAT	847	catalase	plasma membrane	Cellular component	-
AP1G1	164	adaptor-related protein complex 1, gamma 1 subunit	trans-Golgi network membrane	Cellular component	-
APIP	51074	APAF1 interacting protein	L-methionine biosynthetic process from methylthioadenosine	Biological process	-
MTA2	9219	metastasis associated 1 family, member 2	chromatin organization	Biological process	-
HOXD1	3231	homeobox D1	sequence-specific DNA binding	Molecular function	-
MPO	4353	myeloperoxidase	chromatin binding	Molecular function	2829220
PIN4	5303	peptidylprolyl cis/trans isomerase, NIMA-interacting 4	preribosome	Cellular component	19369196
TGFB1	7040	transforming growth factor, beta 1	negative regulation of transcription, DNA-templated	Biological process	15702480
NDUFAF2	91942	NADH dehydrogenase (ubiquinone) complex I, assembly factor 2	NADH dehydrogenase (ubiquinone) activity	Molecular function	-
FAM49B	51571	family with sequence similarity 49, member B	protein binding	Molecular function	25416956
KIAA1804	84451	mixed lineage kinase 4	MAP kinase kinase kinase activity	Molecular function	-
CNGA1	1259	cyclic nucleotide gated channel alpha 1	regulation of membrane potential	Biological process	-
EVL	51466	Enah/Vasp-like	actin binding	Molecular function	-
TGM2	7052	transglutaminase 2	positive regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	-
NPHP4	261734	nephronophthisis 4	sperm motility	Biological process	-
T	6862	T, brachyury homolog (mouse)	embryonic skeletal system development	Biological process	-
FCN2	2220	ficolin (collagen/fibrinogen domain containing lectin) 2	collagen trimer	Cellular component	-
HSP90B1	7184	heat shock protein 90kDa beta (Grp94), member 1	ATP binding	Molecular function	-
SPATA7	55812	spermatogenesis associated 7	photoreceptor connecting cilium	Cellular component	-
FFAR2	2867	free fatty acid receptor 2	positive regulation of interleukin-8 secretion	Biological process	21037097
INPP5J	27124	inositol polyphosphate-5-phosphatase J	plasma membrane	Cellular component	-
PAPOLG	64895	poly(A) polymerase gamma	nucleus	Cellular component	-
TCIRG1	10312	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3	phagosome maturation	Biological process	-
GALR1	2587	galanin receptor 1	adenylate cyclase-activating G-protein coupled receptor signaling pathway	Biological process	-
TKFC	26007	triokinase/FMN cyclase	cytosol	Cellular component	-
EIF5	1983	eukaryotic translation initiation factor 5	translation	Biological process	-
MAP2K1	5604	mitogen-activated protein kinase kinase 1	extracellular exosome	Cellular component	23376485
SUZ12	23512	SUZ12 polycomb repressive complex 2 subunit	gene expression	Biological process	-
TRABD2B	388630	TraB domain containing 2B	integral component of organelle membrane	Cellular component	22726442
TCN2	6948	transcobalamin II	extracellular exosome	Cellular component	23376485
AKAP13	11214	A kinase (PRKA) anchor protein 13	protein phosphorylation	Biological process	1618839
ARIH1	25820	ariadne RBR E3 ubiquitin protein ligase 1	protein binding	Molecular function	10521492
UBE2J2	118424	ubiquitin-conjugating enzyme E2, J2	response to unfolded protein	Biological process	-
PSMB9	5698	proteasome (prosome, macropain) subunit, beta type, 9	protein binding	Molecular function	14733938
RELA	5970	v-rel avian reticuloendotheliosis viral oncogene homolog A	response to insulin	Biological process	-
SLC17A1	6568	solute carrier family 17 (organic anion transporter), member 1	sodium:phosphate symporter activity	Molecular function	-
TUFM	7284	Tu translation elongation factor, mitochondrial	GTP binding	Molecular function	-
HMGN5	79366	high mobility group nucleosome binding domain 5	positive regulation of transcription, DNA-templated	Biological process	11161810
CREBRF	153222	CREB3 regulatory factor	sequence-specific DNA binding	Molecular function	-
ADAM10	102	ADAM metallopeptidase domain 10	cell-cell signaling	Biological process	12714508
ANPEP	290	alanyl (membrane) aminopeptidase	extracellular space	Cellular component	16502470
SLC18A2	6571	solute carrier family 18 (vesicular monoamine transporter), member 2	insulin secretion	Biological process	-
METRN	79006	meteorin, glial cell differentiation regulator	glial cell differentiation	Biological process	-
FAM134B	54463	family with sequence similarity 134, member B	sensory perception of pain	Biological process	19838196
SIX3	6496	SIX homeobox 3	lens development in camera-type eye	Biological process	-
ADORA2B	136	adenosine A2b receptor	adenylate cyclase-activating G-protein coupled receptor signaling pathway	Biological process	-
CLCN5	1184	chloride channel, voltage-sensitive 5	lysosomal membrane	Cellular component	17897319
CRHR1	1394	corticotropin releasing hormone receptor 1	corticotropin-releasing hormone binding	Molecular function	-
RPS27A	6233	ribosomal protein S27a	JNK cascade	Biological process	-
KIR3DS1	3813	killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1	innate immune response	Biological process	-
LMTK2	22853	lemur tyrosine kinase 2	recycling endosome	Cellular component	18029400
SLC23A2	9962	solute carrier family 23 (ascorbic acid transporter), member 2	basolateral plasma membrane	Cellular component	15993839
IL9	3578	interleukin 9	positive regulation of cell growth	Biological process	-
SDS	10993	serine dehydratase	L-serine catabolic process	Biological process	15689518
HIST1H3C	8352	histone cluster 1, H3c	nucleosome assembly	Biological process	25615412
HIST1H2BN	8341	histone cluster 1, H2bn	nucleoplasm	Cellular component	-
GATA2	2624	GATA binding protein 2	RNA polymerase II distal enhancer sequence-specific DNA binding	Molecular function	-
GPR45	11250	G protein-coupled receptor 45	G-protein coupled receptor activity	Molecular function	-
GCDH	2639	glutaryl-CoA dehydrogenase	mitochondrion	Cellular component	-
RARA	5914	retinoic acid receptor, alpha	nucleus	Cellular component	-
NUP214	8021	nucleoporin 214kDa	protein export from nucleus	Biological process	12191473
C9orf9	11092	chromosome 9 open reading frame 9	acrosomal vesicle	Cellular component	-
GPM6B	2824	glycoprotein M6B	ossification	Biological process	-
SLC2A2	6514	solute carrier family 2 (facilitated glucose transporter), member 2	dehydroascorbic acid transporter activity	Molecular function	-
SST	6750	somatostatin	negative regulation of cell proliferation	Biological process	9886848
TRPC5	7224	transient receptor potential cation channel, subfamily C, member 5	ion transmembrane transport	Biological process	-
WNT5A	7474	wingless-type MMTV integration site family, member 5A	embryonic digit morphogenesis	Biological process	-
MBL2	4153	mannose-binding lectin (protein C) 2, soluble	complement activation, classical pathway	Biological process	-
MRPL17	63875	mitochondrial ribosomal protein L17	mitochondrial translation	Biological process	-
TMC6	11322	transmembrane channel-like 6	cytoplasm	Cellular component	12426567
MMP1	4312	matrix metallopeptidase 1	leukocyte migration	Biological process	-
AKAP8	10270	A kinase (PRKA) anchor protein 8	nucleoplasm	Cellular component	-
TYROBP	7305	TYRO protein tyrosine kinase binding protein	integrin-mediated signaling pathway	Biological process	-
PRNP	5621	prion protein	protein homooligomerization	Biological process	-
PPAP2A	8611	phosphatidic acid phosphatase type 2A	negative regulation of cell proliferation	Biological process	9468526
YBX1	4904	Y box binding protein 1	RNA binding	Molecular function	19561594
USP18	11274	ubiquitin specific peptidase 18	nucleus	Cellular component	-
TUBB2B	347733	tubulin, beta 2B class IIb	GTP binding	Molecular function	-
TDRD9	122402	tudor domain containing 9	P granule	Cellular component	-
APOBEC1	339	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	response to gamma radiation	Biological process	-
MED12	9968	mediator complex subunit 12	RNA polymerase II transcription cofactor activity	Molecular function	10198638
TUB	7275	tubby bipartite transcription factor	protein complex binding	Molecular function	20889716
CREB3L3	84699	cAMP responsive element binding protein 3-like 3	transcription, DNA-templated	Biological process	-
AKIRIN1	79647	akirin 1	protein binding	Molecular function	25416956
ACTL6B	51412	actin-like 6B	transcription coactivator activity	Molecular function	8804307
IP6K3	117283	inositol hexakisphosphate kinase 3	phosphatidylinositol metabolic process	Biological process	11502751
CDH1	999	cadherin 1, type 1, E-cadherin (epithelial)	cell junction	Cellular component	17047063
MCM7	4176	minichromosome maintenance complex component 7	DNA replication initiation	Biological process	-
PTH2R	5746	parathyroid hormone 2 receptor	plasma membrane	Cellular component	-
RAB9A	9367	RAB9A, member RAS oncogene family	extracellular exosome	Cellular component	20458337
CYP7B1	9420	cytochrome P450, family 7, subfamily B, polypeptide 1	positive regulation of epithelial cell proliferation	Biological process	-
FRG2	448831	FSHD region gene 2	nucleus	Cellular component	-
ADPGK	83440	ADP-dependent glucokinase	glycolytic process	Biological process	-
AMDHD2	51005	amidohydrolase domain containing 2	protein binding	Molecular function	25416956
FLOT2	2319	flotillin 2	negative regulation of gene expression	Biological process	24612608
SHPRH	257218	SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase	DNA binding	Molecular function	-
PRLHR	2834	prolactin releasing hormone receptor	plasma membrane	Cellular component	-
RAB3A	5864	RAB3A, member RAS oncogene family	plasma membrane	Cellular component	-
SLC7A1	6541	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1	plasma membrane	Cellular component	-
PDE8B	8622	phosphodiesterase 8B	cytosol	Cellular component	-
TGFBR1	7046	transforming growth factor, beta receptor 1	neuron fate commitment	Biological process	-
SSC5D	284297	scavenger receptor cysteine rich family, 5 domains	innate immune response	Biological process	-
NYAP2	57624	neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2	protein binding	Molecular function	25416956
PMS1	5378	PMS1 postmeiotic segregation increased 1 (S. cerevisiae)	mismatch repair	Biological process	-
GBAS	2631	glioblastoma amplified sequence	ATP biosynthetic process	Biological process	20888800
RBX1	9978	ring-box 1, E3 ubiquitin protein ligase	ubiquitin-protein transferase activity	Molecular function	15983046
DISP1	84976	dispatched homolog 1 (Drosophila)	peptide transporter activity	Molecular function	-
SLC8A1	6546	solute carrier family 8 (sodium/calcium exchanger), member 1	positive regulation of bone mineralization	Biological process	25589784
TP53	7157	tumor protein p53	neuron apoptotic process	Biological process	-
UFC1	51506	ubiquitin-fold modifier conjugating enzyme 1	response to endoplasmic reticulum stress	Biological process	23152784
ANK3	288	ankyrin 3, node of Ranvier (ankyrin G)	lateral plasma membrane	Cellular component	14757759
MVB12B	89853	multivesicular body subunit 12B	extracellular exosome	Cellular component	19056867
ATP1B1	481	ATPase, Na+/K+ transporting, beta 1 polypeptide	cardiac muscle contraction	Biological process	-
CD46	4179	CD46 molecule, complement regulatory protein	focal adhesion	Cellular component	21423176
NQO1	1728	NAD(P)H dehydrogenase, quinone 1	cellular nitrogen compound metabolic process	Biological process	-
CNDP1	84735	carnosine dipeptidase 1 (metallopeptidase M20 family)	tripeptidase activity	Molecular function	-
DRD2	1813	dopamine receptor D2	intracellular	Cellular component	1331329
CHRNA1	1134	cholinergic receptor, nicotinic, alpha 1 (muscle)	neuronal action potential	Biological process	8872460
EOMES	8320	eomesodermin	brain development	Biological process	17353897
ATCAY	85300	ataxia, cerebellar, Cayman type	synapse	Cellular component	-
CYP2C9	1559	cytochrome P450, family 2, subfamily C, polypeptide 9	monocarboxylic acid metabolic process	Biological process	19651758
SPEF2	79925	sperm flagellar 2	multicellular organismal aging	Biological process	-
CCNA1	8900	cyclin A1	G1/S transition of mitotic cell cycle	Biological process	-
BMP4	652	bone morphogenetic protein 4	chondrocyte differentiation	Biological process	-
STAM	8027	signal transducing adaptor molecule (SH3 domain and ITAM motif) 1	membrane organization	Biological process	-
CPNE3	8895	copine III	cytoplasm	Cellular component	11041869
RBM17	84991	RNA binding motif protein 17	alternative mRNA splicing, via spliceosome	Biological process	17589525
CLDN23	137075	claudin 23	bicellular tight junction	Cellular component	-
RPS3	6188	ribosomal protein S3	negative regulation of DNA repair	Biological process	17049931
FAF1	11124	Fas (TNFRSF6) associated factor 1	nuclear envelope	Cellular component	-
TBX1	6899	T-box 1	protein dimerization activity	Molecular function	17273972
ADORA2A	135	adenosine A2a receptor	enzyme binding	Molecular function	16339847
TOB2	10766	transducer of ERBB2, 2	protein binding	Molecular function	23340509
POLR2E	5434	polymerase (RNA) II (DNA directed) polypeptide E, 25kDa	transcription elongation from RNA polymerase III promoter	Biological process	-
GRM7	2917	glutamate receptor, metabotropic 7	serine binding	Molecular function	9144652
SLC7A5	8140	solute carrier family 7 (amino acid transporter light chain, L system), member 5	neutral amino acid transport	Biological process	-
SEC22A	26984	SEC22 vesicle trafficking protein homolog A (S. cerevisiae)	transporter activity	Molecular function	8621431
HNRNPH1	3187	heterogeneous nuclear ribonucleoprotein H1 (H)	gene expression	Biological process	-
MAN1B1	11253	mannosidase, alpha, class 1B, member 1	endoplasmic reticulum	Cellular component	18003979
HVCN1	84329	hydrogen voltage gated channel 1	cellular response to pH	Biological process	22020278
COG3	83548	component of oligomeric golgi complex 3	cis-Golgi network	Cellular component	-
HNRNPA3	220988	heterogeneous nuclear ribonucleoprotein A3	mRNA splicing, via spliceosome	Biological process	-
MARK3	4140	MAP/microtubule affinity-regulating kinase 3	plasma membrane	Cellular component	21145462
PLA2G4D	283748	phospholipase A2, group IVD (cytosolic)	cytoplasmic vesicle membrane	Cellular component	-
GRIN1	2902	glutamate receptor, ionotropic, N-methyl D-aspartate 1	regulation of synapse assembly	Biological process	-
FIGF	2277	c-fos induced growth factor (vascular endothelial growth factor D)	vascular endothelial growth factor receptor signaling pathway	Biological process	-
WNT3A	89780	wingless-type MMTV integration site family, member 3A	extracellular matrix organization	Biological process	-
MAP3K8	1326	mitogen-activated protein kinase kinase kinase 8	cytoplasm	Cellular component	-
IQGAP3	128239	IQ motif containing GTPase activating protein 3	Ras protein signal transduction	Biological process	-
CXCR4	7852	chemokine (C-X-C motif) receptor 4	dendritic cell chemotaxis	Biological process	16621978
HSPA5	3309	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	glycoprotein binding	Molecular function	20477988
CTSV	1515	cathepsin V	autophagic cell death	Biological process	-
SLC27A5	10998	solute carrier family 27 (fatty acid transporter), member 5	bile acid biosynthetic process	Biological process	-
GPM6B	2824	glycoprotein M6B	nervous system development	Biological process	8661015
ZMYM2	7750	zinc finger, MYM-type 2	transcription, DNA-templated	Biological process	-
FOXR1	283150	forkhead box R1	transcription from RNA polymerase II promoter	Biological process	-
MUC6	4588	mucin 6, oligomeric mucus/gel-forming	post-translational protein modification	Biological process	-
PLEKHF2	79666	pleckstrin homology domain containing, family F (with FYVE domain) member 2	metal ion binding	Molecular function	-
PRSS3	5646	protease, serine, 3	extracellular space	Cellular component	6698368
GTSE1	51512	G-2 and S-phase expressed 1	cytoplasmic microtubule	Cellular component	10974554
TMPRSS6	164656	transmembrane protease, serine 6	negative regulation of transcription, DNA-templated	Biological process	25156943
ZSWIM5	57643	zinc finger, SWIM-type containing 5	zinc ion binding	Molecular function	-
F5	2153	coagulation factor V (proaccelerin, labile factor)	Golgi apparatus	Cellular component	-
DDX3Y	8653	DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked	ATP binding	Molecular function	-
SNCB	6620	synuclein, beta	dopamine metabolic process	Biological process	-
PLEC	5339	plectin	poly(A) RNA binding	Molecular function	22658674
MAPK1	5594	mitogen-activated protein kinase 1	positive regulation of translation	Biological process	-
KCNJ5	3762	potassium channel, inwardly rectifying subfamily J, member 5	plasma membrane	Cellular component	-
PDK3	5165	pyruvate dehydrogenase kinase, isozyme 3	ATP binding	Molecular function	15861126
GAD2	2572	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)	response to drug	Biological process	-
NRXN2	9379	neurexin 2	transmembrane signaling receptor activity	Molecular function	18923512
CYB5R3	1727	cytochrome b5 reductase 3	mitochondrial inner membrane	Cellular component	-
BRSK1	84446	BR serine/threonine kinase 1	neuron differentiation	Biological process	-
PLCD4	84812	phospholipase C, delta 4	phosphatidylinositol phospholipase C activity	Molecular function	-
XDH	7498	xanthine dehydrogenase	xanthine dehydrogenase activity	Molecular function	8670112
CHMP1B	57132	charged multivesicular body protein 1B	cytosol	Cellular component	-
ADGRA3	166647	adhesion G protein-coupled receptor A3	G-protein coupled receptor signaling pathway	Biological process	-
ACAP3	116983	ArfGAP with coiled-coil, ankyrin repeat and PH domains 3	positive regulation of GTPase activity	Biological process	-
HLA-C	3107	major histocompatibility complex, class I, C	regulation of immune response	Biological process	-
DMRTC2	63946	DMRT-like family C2	sex differentiation	Biological process	-
MCL1	4170	myeloid cell leukemia 1	multicellular organismal development	Biological process	-
CHML	1122	choroideremia-like (Rab escort protein 2)	protein geranylgeranylation	Biological process	12356470
CCNT1	904	cyclin T1	transcription regulatory region DNA binding	Molecular function	-
NRXN1	9378	neurexin 1	extracellular matrix organization	Biological process	-
DDX43	55510	DEAD (Asp-Glu-Ala-Asp) box polypeptide 43	intracellular	Cellular component	-
KIF2C	11004	kinesin family member 2C	ATPase activity	Molecular function	-
CRMP1	1400	collapsin response mediator protein 1	neuronal cell body	Cellular component	-
CHIC1	53344	cysteine-rich hydrophobic domain 1	cytoplasmic membrane-bounded vesicle	Cellular component	-
TSKU	25987	tsukushi, small leucine rich proteoglycan	extracellular space	Cellular component	-
UFD1L	7353	ubiquitin fusion degradation 1 like (yeast)	ubiquitin-dependent protein catabolic process	Biological process	9063746
TRIM14	9830	tripartite motif containing 14	negative regulation of viral transcription	Biological process	18248090
PKN1	5585	protein kinase N1	protein binding	Molecular function	12761180
GHRHR	2692	growth hormone releasing hormone receptor	nuclear matrix	Cellular component	10461027
KIAA0141	9812	KIAA0141	protein binding	Molecular function	20563667
ASAP3	55616	ArfGAP with SH3 domain, ankyrin repeat and PH domain 3	metal ion binding	Molecular function	-
IRX5	10265	iroquois homeobox 5	response to stimulus	Biological process	-
CHMP2B	25978	charged multivesicular body protein 2B	cytosol	Cellular component	-
OR8J3	81168	olfactory receptor, family 8, subfamily J, member 3	olfactory receptor activity	Molecular function	-
TAF1L	138474	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like	protein serine/threonine kinase activity	Molecular function	12217962
PITPNM1	9600	phosphatidylinositol transfer protein, membrane-associated 1	cleavage furrow	Cellular component	-
WNT7A	7476	wingless-type MMTV integration site family, member 7A	synapse organization	Biological process	-
GYPC	2995	glycophorin C (Gerbich blood group)	membrane	Cellular component	19946888
SPNS2	124976	spinster homolog 2 (Drosophila)	integral component of membrane	Cellular component	-
SOX8	30812	SRY (sex determining region Y)-box 8	nuclear transcription factor complex	Cellular component	-
H2AFY	9555	H2A histone family, member Y	protein binding	Molecular function	22391447
NUP88	4927	nucleoporin 88kDa	carbohydrate metabolic process	Biological process	-
OR51D1	390038	olfactory receptor, family 51, subfamily D, member 1	integral component of membrane	Cellular component	-
FOSL2	2355	FOS-like antigen 2	nucleoplasm	Cellular component	-
URAD	646625	ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase	cellular_component	Cellular component	-
DNM1L	10059	dynamin 1-like	mitochondrial membrane fission	Biological process	11514614
CHUK	1147	conserved helix-loop-helix ubiquitous kinase	cytoplasmic side of plasma membrane	Cellular component	-
TTLL3	26140	tubulin tyrosine ligase-like family member 3	microtubule	Cellular component	-
DGKD	8527	diacylglycerol kinase, delta 130kDa	endocytosis	Biological process	-
GPN2	54707	GPN-loop GTPase 2	GTP binding	Molecular function	-
ZNF335	63925	zinc finger protein 335	regulation of histone H3-K4 methylation	Biological process	-
RFWD2	64326	ring finger and WD repeat domain 2, E3 ubiquitin protein ligase	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Biological process	19805145
HIST1H2BM	8342	histone cluster 1, H2bm	nucleosome	Cellular component	9439656
CCL2	6347	chemokine (C-C motif) ligand 2	axon terminus	Cellular component	-
SERP1	27230	stress-associated endoplasmic reticulum protein 1	positive regulation of insulin secretion	Biological process	-
CCNB2	9133	cyclin B2	microtubule cytoskeleton	Cellular component	-
LIMK1	3984	LIM domain kinase 1	focal adhesion	Cellular component	-
ACACA	31	acetyl-CoA carboxylase alpha	nucleolus	Cellular component	-
CD44	960	CD44 molecule (Indian blood group)	focal adhesion	Cellular component	21423176
SLC25A27	9481	solute carrier family 25, member 27	mitochondrion	Cellular component	10025957
SPARCL1	8404	SPARC-like 1 (hevin)	extracellular space	Cellular component	16502470
FCN3	8547	ficolin (collagen/fibrinogen domain containing) 3	blood microparticle	Cellular component	22516433
DVL2	1856	dishevelled segment polarity protein 2	cytosol	Cellular component	-
FAM160A2	84067	family with sequence similarity 160, member A2	early endosome to late endosome transport	Biological process	18799622
CD44	960	CD44 molecule (Indian blood group)	basolateral plasma membrane	Cellular component	-
UCKL1	54963	uridine-cytidine kinase 1-like 1	nucleus	Cellular component	-
GPR15	2838	G protein-coupled receptor 15	T cell migration	Biological process	-
BST2	684	bone marrow stromal cell antigen 2	B cell activation	Biological process	-
FAM162A	26355	family with sequence similarity 162, member A	cytoplasm	Cellular component	-
LRRTM1	347730	leucine rich repeat transmembrane neuronal 1	negative regulation of receptor internalization	Biological process	-
CRY2	1408	cryptochrome circadian clock 2	damaged DNA binding	Molecular function	12627958
GNAQ	2776	guanine nucleotide binding protein (G protein), q polypeptide	phospholipase C-activating dopamine receptor signaling pathway	Biological process	-
QKI	9444	QKI, KH domain containing, RNA binding	regulation of translation	Biological process	-
LRRTM1	347730	leucine rich repeat transmembrane neuronal 1	cell surface	Cellular component	17667961
NR1D1	9572	nuclear receptor subfamily 1, group D, member 1	dendritic spine	Cellular component	-
NPNT	255743	nephronectin	cell-cell adhesion mediated by integrin	Biological process	15754038
IL1B	3553	interleukin 1, beta	stimulatory C-type lectin receptor signaling pathway	Biological process	-
USP42	84132	ubiquitin specific peptidase 42	protein deubiquitination	Biological process	-
ICAM2	3384	intercellular adhesion molecule 2	membrane	Cellular component	19946888
FBXO18	84893	F-box protein, helicase, 18	DNA binding	Molecular function	-
LOC391742	391742	TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa pseudogene	transcription initiation from RNA polymerase II promoter	Biological process	-
ATP6V1G3	127124	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3	plasma membrane	Cellular component	17360703
SRSF6	6431	serine/arginine-rich splicing factor 6	regulation of wound healing	Biological process	24440982
ANK2	287	ankyrin 2, neuronal	protein localization to plasma membrane	Biological process	-
MNX1	3110	motor neuron and pancreas homeobox 1	sequence-specific DNA binding transcription factor activity	Molecular function	9843207
MX2	4600	MX dynamin-like GTPase 2	cytosol	Cellular component	-
CACNG8	59283	calcium channel, voltage-dependent, gamma subunit 8	calcium ion transmembrane transport	Biological process	-
PLAU	5328	plasminogen activator, urokinase	serine-type endopeptidase activity	Molecular function	-
TBX15	6913	T-box 15	protein heterodimerization activity	Molecular function	-
TNFSF10	8743	tumor necrosis factor (ligand) superfamily, member 10	regulation of extrinsic apoptotic signaling pathway via death domain receptors	Biological process	-
HPS1	3257	Hermansky-Pudlak syndrome 1	protein dimerization activity	Molecular function	12663659
RGS13	6003	regulator of G-protein signaling 13	cytoplasm	Cellular component	-
XYLT2	64132	xylosyltransferase II	protein xylosyltransferase activity	Molecular function	11099377
MKL1	57591	megakaryoblastic leukemia (translocation) 1	nucleus	Cellular component	14970199
DAPK2	23604	death-associated protein kinase 2	identical protein binding	Molecular function	10629061
TCP11	6954	t-complex 11, testis-specific	spermatogenesis	Biological process	-
TAP2	6891	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	protein binding	Molecular function	12213826
ADCY9	115	adenylate cyclase 9	integral component of plasma membrane	Cellular component	9628827
IP6K3	117283	inositol hexakisphosphate kinase 3	small molecule metabolic process	Biological process	-
HNRNPL	3191	heterogeneous nuclear ribonucleoprotein L	RNA binding	Molecular function	2687284
RPS17	6218	ribosomal protein S17	cytosol	Cellular component	-
IKBKG	8517	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	positive regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	-
KLKB1	3818	kallikrein B, plasma (Fletcher factor) 1	extracellular space	Cellular component	89876
ZNF324B	388569	zinc finger protein 324B	regulation of transcription, DNA-templated	Biological process	-
IL18R1	8809	interleukin 18 receptor 1	natural killer cell activation	Biological process	-
CRACR2A	84766	calcium release activated channel regulator 2A	membrane	Cellular component	19946888
PHF21A	51317	PHD finger protein 21A	negative regulation of transcription from RNA polymerase II promoter	Biological process	15325272
IKZF3	22806	IKAROS family zinc finger 3 (Aiolos)	metal ion binding	Molecular function	-
DSC2	1824	desmocollin 2	regulation of heart rate by cardiac conduction	Biological process	23863954
ALAS2	212	5'-aminolevulinate synthase 2	hemoglobin biosynthetic process	Biological process	-
AGO2	27161	argonaute RISC catalytic component 2	gene expression	Biological process	-
ADRB2	154	adrenoceptor beta 2, surface	apical plasma membrane	Cellular component	-
PRDX1	5052	peroxiredoxin 1	protein homodimerization activity	Molecular function	-
PDGFRB	5159	platelet-derived growth factor receptor, beta polypeptide	platelet activating factor receptor activity	Molecular function	2536956
STAR	6770	steroidogenic acute regulatory protein	cellular response to growth hormone stimulus	Biological process	-
PPIF	10105	peptidylprolyl isomerase F	cellular response to calcium ion	Biological process	-
BCL3	602	B-cell CLL/lymphoma 3	protein complex	Cellular component	16280327
BAD	572	BCL2-associated agonist of cell death	positive regulation of T cell differentiation	Biological process	-
SYT9	143425	synaptotagmin IX	calcium ion binding	Molecular function	-
AKR1C3	8644	aldo-keto reductase family 1, member C3	positive regulation of protein kinase B signaling	Biological process	18508192
PCNT	5116	pericentrin	ciliary basal body	Cellular component	-
ATP9A	10079	ATPase, class II, type 9A	metabolic process	Biological process	-
HDAC2	3066	histone deacetylase 2	nuclear chromatin	Cellular component	16217013
HCN2	610	hyperpolarization activated cyclic nucleotide gated potassium channel 2	identical protein binding	Molecular function	22006928
OOEP	441161	oocyte expressed protein	protein phosphorylation	Biological process	-
PSMB5	5693	proteasome (prosome, macropain) subunit, beta type, 5	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	Biological process	-
S100A14	57402	S100 calcium binding protein A14	calcium ion homeostasis	Biological process	16682778
CREBL2	1389	cAMP responsive element binding protein-like 2	nucleus	Cellular component	-
ATP13A2	23400	ATPase type 13A2	cellular response to manganese ion	Biological process	23628791
DAB2IP	153090	DAB2 interacting protein	negative regulation of vascular endothelial growth factor signaling pathway	Biological process	-
F2RL1	2150	coagulation factor II (thrombin) receptor-like 1	plasma membrane	Cellular component	-
NPAS4	266743	neuronal PAS domain protein 4	nucleus	Cellular component	-
JARID2	3720	jumonji, AT rich interactive domain 2	gene expression	Biological process	-
EFNB1	1947	ephrin-B1	neural crest cell migration	Biological process	-
LHX9	56956	LIM homeobox 9	negative regulation of transcription, DNA-templated	Biological process	-
MYOD1	4654	myogenic differentiation 1	protein heterodimerization activity	Molecular function	-
COL11A1	1301	collagen, type XI, alpha 1	protein binding, bridging	Molecular function	10486316
PAPSS2	9060	3'-phosphoadenosine 5'-phosphosulfate synthase 2	carbohydrate metabolic process	Biological process	-
GPR150	285601	G protein-coupled receptor 150	G-protein coupled receptor activity	Molecular function	-
AP2A2	161	adaptor-related protein complex 2, alpha 2 subunit	cytosol	Cellular component	-
CUBN	8029	cubilin (intrinsic factor-cobalamin receptor)	small molecule metabolic process	Biological process	-
SLC5A9	200010	solute carrier family 5 (sodium/sugar cotransporter), member 9	extracellular exosome	Cellular component	19056867
HP1BP3	50809	heterochromatin protein 1, binding protein 3	protein binding	Molecular function	20042602
SNX17	9784	sorting nexin 17	cytoplasmic vesicle membrane	Cellular component	-
SMOC2	64094	SPARC related modular calcium binding 2	signal transduction	Biological process	-
ZNFX1	57169	zinc finger, NFX1-type containing 1	poly(A) RNA binding	Molecular function	22658674
MED8	112950	mediator complex subunit 8	nucleoplasm	Cellular component	-
TRPV4	59341	transient receptor potential cation channel, subfamily V, member 4	SH2 domain binding	Molecular function	-
SF3B6	51639	splicing factor 3b, subunit 6, 14kDa	nucleotide binding	Molecular function	-
NOTCH1	4851	notch 1	negative regulation of cell migration involved in sprouting angiogenesis	Biological process	20616313
OAS1	4938	2'-5'-oligoadenylate synthetase 1, 40/46kDa	regulation of ribonuclease activity	Biological process	19923450
SENP2	59343	SUMO1/sentrin/SMT3 specific peptidase 2	protein binding	Molecular function	11896061
PPME1	51400	protein phosphatase methylesterase 1	negative regulation of catalytic activity	Biological process	10318862
MSR1	4481	macrophage scavenger receptor 1	positive regulation of cholesterol storage	Biological process	-
APBA2	321	amyloid beta (A4) precursor protein-binding, family A, member 2	synaptic vesicle	Cellular component	-
OCRL	4952	oculocerebrorenal syndrome of Lowe	inositol phosphate phosphatase activity	Molecular function	1321346
NOTCH1	4851	notch 1	glomerular mesangial cell development	Biological process	-
NUP107	57122	nucleoporin 107kDa	nucleocytoplasmic transporter activity	Molecular function	11684705
MKS1	54903	Meckel syndrome, type 1	centrosome	Cellular component	19208769
BMP2	650	bone morphogenetic protein 2	BMP signaling pathway involved in heart induction	Biological process	19736317
ATF6	22926	activating transcription factor 6	nucleoplasm	Cellular component	-
C1QTNF1	114897	C1q and tumor necrosis factor related protein 1	protein binding	Molecular function	12409230
LAMC2	3918	laminin, gamma 2	hemidesmosome assembly	Biological process	-
RHOBTB3	22836	Rho-related BTB domain containing 3	Rab GTPase binding	Molecular function	19490898
VPS16	64601	vacuolar protein sorting 16 homolog (S. cerevisiae)	axon	Cellular component	-
CCDC137	339230	coiled-coil domain containing 137	nucleolus	Cellular component	-
PIK3CD	5293	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	fibroblast growth factor receptor signaling pathway	Biological process	-
DAB2	1601	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)	apical plasma membrane	Cellular component	-
INS	3630	insulin	positive regulation of glycogen biosynthetic process	Biological process	17925406
ZXDA	7789	zinc finger, X-linked, duplicated A	metal ion binding	Molecular function	-
CUX1	1523	cut-like homeobox 1	transcription, DNA-templated	Biological process	-
HYAL2	8692	hyaluronoglucosaminidase 2	viral entry into host cell	Biological process	-
CDC42EP1	11135	CDC42 effector protein (Rho GTPase binding) 1	Golgi apparatus	Cellular component	-
CD209	30835	CD209 molecule	protein binding	Molecular function	12609975
GGCT	79017	gamma-glutamylcyclotransferase	protein homodimerization activity	Molecular function	17932939
OR52E2	119678	olfactory receptor, family 52, subfamily E, member 2	G-protein coupled receptor signaling pathway	Biological process	-
ITGA4	3676	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	B cell differentiation	Biological process	1715889
STMN2	11075	stathmin 2	axon	Cellular component	-
MAGEF1	64110	melanoma antigen family F1	protein binding	Molecular function	25416956
AURKA	6790	aurora kinase A	anterior/posterior axis specification	Biological process	-
RPS6KB1	6198	ribosomal protein S6 kinase, 70kDa, polypeptide 1	cell junction	Cellular component	-
FOXJ1	2302	forkhead box J1	epithelium development	Biological process	9073514
NF1	4763	neurofibromin 1	negative regulation of protein kinase activity	Biological process	-
GHSR	2693	growth hormone secretagogue receptor	decidualization	Biological process	17494105
GBF1	8729	golgi brefeldin A resistant guanine nucleotide exchange factor 1	protein localization to endoplasmic reticulum tubular network	Biological process	17956946
RASD2	23551	RASD family, member 2	plasma membrane	Cellular component	-
TYR	7299	tyrosinase	protein homodimerization activity	Molecular function	-
CCDC39	339829	coiled-coil domain containing 39	axoneme	Cellular component	21131972
RBCK1	10616	RanBP-type and C3HC4-type zinc finger containing 1	positive regulation of NF-kappaB transcription factor activity	Biological process	19136968
DDX52	11056	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52	nucleolus	Cellular component	-
FRY	10129	furry homolog (Drosophila)	microtubule organizing center	Cellular component	-
FOXP3	50943	forkhead box P3	negative regulation of T-helper 17 cell differentiation	Biological process	23169781
CYP2D6	1565	cytochrome P450, family 2, subfamily D, polypeptide 6	drug catabolic process	Biological process	15039299
HNRNPF	3185	heterogeneous nuclear ribonucleoprotein F	poly(A) RNA binding	Molecular function	22658674
USP48	84196	ubiquitin specific peptidase 48	cysteine-type endopeptidase activity	Molecular function	-
TPP2	7174	tripeptidyl peptidase II	aminopeptidase activity	Molecular function	-
CIDEB	27141	cell death-inducing DFFA-like effector b	lipid particle	Cellular component	-
SLC25A13	10165	solute carrier family 25 (aspartate/glutamate carrier), member 13	L-aspartate transmembrane transporter activity	Molecular function	11566871
ING2	3622	inhibitor of growth family, member 2	regulation of transcription, DNA-templated	Biological process	15243141
PRKAR2B	5577	protein kinase, cAMP-dependent, regulatory, type II, beta	energy reserve metabolic process	Biological process	-
RPP38	10557	ribonuclease P/MRP 38kDa subunit	RNA phosphodiester bond hydrolysis, endonucleolytic	Biological process	9630247
DIRAS2	54769	DIRAS family, GTP-binding RAS-like 2	GTP binding	Molecular function	12194967
EDNRB	1910	endothelin receptor type B	integral component of plasma membrane	Cellular component	8810293
AIMP1	9255	aminoacyl tRNA synthetase complex-interacting multifunctional protein 1	tRNA binding	Molecular function	11306575
CRYGD	1421	crystallin, gamma D	protein binding	Molecular function	22289178
IL12A	3592	interleukin 12A	response to virus	Biological process	16548883
CYP1B1	1545	cytochrome P450, family 1, subfamily B, polypeptide 1	monooxygenase activity	Molecular function	9097971
ERVK-26	103539957	endogenous retrovirus group K, member 26	RNA binding	Molecular function	-
MSX2	4488	msh homeobox 2	anterior/posterior pattern specification	Biological process	-
HDAC9	9734	histone deacetylase 9	nucleoplasm	Cellular component	-
SLC28A2	9153	solute carrier family 28 (concentrative nucleoside transporter), member 2	purine nucleoside transmembrane transporter activity	Molecular function	9435697
GATA3	2625	GATA binding protein 3	transcription from RNA polymerase II promoter	Biological process	1871134
DDX3X	1654	DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked	DNA duplex unwinding	Biological process	21589879
SEMA5A	9037	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	positive regulation of endothelial cell chemotaxis	Biological process	-
SNAP23	8773	synaptosomal-associated protein, 23kDa	synapse	Cellular component	-
CDC25B	994	cell division cycle 25B	mitotic cell cycle	Biological process	9188863
ZNF582	147948	zinc finger protein 582	DNA binding	Molecular function	-
SNRPE	6635	small nuclear ribonucleoprotein polypeptide E	nucleus	Cellular component	23246290
UTS2	10911	urotensin 2	negative regulation of urine volume	Biological process	-
TSR3	115939	TSR3, 20S rRNA accumulation, homolog (S. cerevisiae)	maturation of SSU-rRNA	Biological process	-
ZC3H12D	340152	zinc finger CCCH-type containing 12D	cytoplasm	Cellular component	19531561
SKAP2	8935	src kinase associated phosphoprotein 2	plasma membrane	Cellular component	11390434
PLEKHA1	59338	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	luteinization	Biological process	-
CMPK1	51727	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic	cytosol	Cellular component	-
SLC16A13	201232	solute carrier family 16, member 13	monocarboxylic acid transmembrane transporter activity	Molecular function	-
GGTLC2	91227	gamma-glutamyltransferase light chain 2	leukotriene biosynthetic process	Biological process	-
SETD7	80854	SET domain containing (lysine methyltransferase) 7	nucleolus	Cellular component	-
FCGR2B	2213	Fc fragment of IgG, low affinity IIb, receptor (CD32)	protein binding	Molecular function	10382761
FZD7	8324	frizzled class receptor 7	protein binding	Molecular function	18256285
VDR	7421	vitamin D (1,25- dihydroxyvitamin D3) receptor	transcription initiation from RNA polymerase II promoter	Biological process	-
DAZ2	57055	deleted in azoospermia 2	cell differentiation	Biological process	-
NODAL	4838	nodal growth differentiation factor	extracellular space	Cellular component	21656830
FOXL1	2300	forkhead box L1	proteoglycan biosynthetic process	Biological process	-
REG1B	5968	regenerating islet-derived 1 beta	carbohydrate binding	Molecular function	-
CDR2	1039	cerebellar degeneration-related protein 2, 62kDa	cytoplasm	Cellular component	-
KIZ	55857	kizuna centrosomal protein	protein kinase binding	Molecular function	16980960
RPS6KB1	6198	ribosomal protein S6 kinase, 70kDa, polypeptide 1	signal transduction	Biological process	1922062
ARIH1	25820	ariadne RBR E3 ubiquitin protein ligase 1	ubiquitin protein ligase binding	Molecular function	11278816
DZIP1	22873	DAZ interacting zinc finger protein 1	nucleus	Cellular component	15081113
ANAPC10	10393	anaphase promoting complex subunit 10	mitotic cell cycle	Biological process	-
FOXG1	2290	forkhead box G1	positive regulation of neuroblast proliferation	Biological process	-
COX6C	1345	cytochrome c oxidase subunit VIc	cellular metabolic process	Biological process	-
PSMB8	5696	proteasome (prosome, macropain) subunit, beta type, 8	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological process	-
PF4	5196	platelet factor 4	G-protein coupled receptor signaling pathway	Biological process	-
HNF4A	3172	hepatocyte nuclear factor 4, alpha	DNA binding	Molecular function	10551874
ZNF880	400713	zinc finger protein 880	intracellular	Cellular component	-
GNS	2799	glucosamine (N-acetyl)-6-sulfatase	protein binding	Molecular function	17474147
ZNF136	7695	zinc finger protein 136	transcription from RNA polymerase II promoter	Biological process	7649249
KDELR2	11014	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2	intracellular protein transport	Biological process	1325562
PEG3	5178	paternally expressed 3	apoptotic process	Biological process	-
PDCD6IP	10015	programmed cell death 6 interacting protein	endoplasmic reticulum exit site	Cellular component	16957052
TTYH1	57348	tweety family member 1	iron ion transmembrane transport	Biological process	10950931
SSTR3	6753	somatostatin receptor 3	cell-cell signaling	Biological process	1337145
NRIP1	8204	nuclear receptor interacting protein 1	histone deacetylase complex	Cellular component	-
OPN1MW	2652	opsin 1 (cone pigments), medium-wave-sensitive	visual perception	Biological process	-
LAMA1	284217	laminin, alpha 1	cell-cell junction	Cellular component	-
MYH9	4627	myosin, heavy chain 9, non-muscle	focal adhesion	Cellular component	-
MAPK1	5594	mitogen-activated protein kinase 1	cellular response to DNA damage stimulus	Biological process	-
MMP20	9313	matrix metallopeptidase 20	extracellular matrix organization	Biological process	-
LCN1	3933	lipocalin 1	sensory perception of taste	Biological process	-
BHLHB9	80823	basic helix-loop-helix domain containing, class B, 9	positive regulation of dendritic spine morphogenesis	Biological process	-
HLA-DQB1	3119	major histocompatibility complex, class II, DQ beta 1	lysosomal membrane	Cellular component	-
AHI1	54806	Abelson helper integration site 1	regulation of behavior	Biological process	-
GRIN2C	2905	glutamate receptor, ionotropic, N-methyl D-aspartate 2C	ionotropic glutamate receptor signaling pathway	Biological process	-
PSMB6	5694	proteasome (prosome, macropain) subunit, beta type, 6	antigen processing and presentation of exogenous peptide antigen via MHC class I	Biological process	-
CCNC	892	cyclin C	transcription, DNA-templated	Biological process	-
CSTF2	1478	cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa	mRNA cleavage	Biological process	1741396
SERPINB9	5272	serpin peptidase inhibitor, clade B (ovalbumin), member 9	response to bacterium	Biological process	22090449
HECTD3	79654	HECT domain containing E3 ubiquitin protein ligase 3	protein binding	Molecular function	18194665
OAS1	4938	2'-5'-oligoadenylate synthetase 1, 40/46kDa	mitochondrion	Cellular component	-
FEZF1	389549	FEZ family zinc finger 1	olfactory bulb development	Biological process	-
ZNF563	147837	zinc finger protein 563	regulation of transcription, DNA-templated	Biological process	-
H2AFB1	474382	H2A histone family, member B1	nucleosome assembly	Biological process	22795134
KDM6A	7403	lysine (K)-specific demethylase 6A	oxidation-reduction process	Biological process	-
AKAP6	9472	A kinase (PRKA) anchor protein 6	protein complex scaffold	Molecular function	-
INHBA	3624	inhibin, beta A	positive regulation of cellular protein metabolic process	Biological process	21828274
GADD45GIP1	90480	growth arrest and DNA-damage-inducible, gamma interacting protein 1	mitochondrial translational elongation	Biological process	-
SLX1B	79008	SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)	Slx1-Slx4 complex	Cellular component	19595721
CCKBR	887	cholecystokinin B receptor	cholecystokinin receptor activity	Molecular function	7681836
DPF2	5977	D4, zinc and double PHD fingers family 2	apoptotic process	Biological process	8812431
NKX6-1	4825	NK6 homeobox 1	smoothened signaling pathway	Biological process	-
FLRT3	23767	fibronectin leucine rich transmembrane protein 3	extracellular space	Cellular component	-
CDKN2D	1032	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	Biological process	15750620
PSMB2	5690	proteasome (prosome, macropain) subunit, beta type, 2	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	Biological process	-
SOX15	6665	SRY (sex determining region Y)-box 15	nucleus	Cellular component	8332506
PDPN	10630	podoplanin	amino acid transmembrane transporter activity	Molecular function	-
FSTL3	10272	follistatin-like 3 (secreted glycoprotein)	secretory granule	Cellular component	-
ID3	3399	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	regulation of DNA replication	Biological process	-
KCNQ1	3784	potassium channel, voltage gated KQT-like subfamily Q, member 1	voltage-gated potassium channel complex	Cellular component	16002409
DHRS13	147015	dehydrogenase/reductase (SDR family) member 13	oxidoreductase activity	Molecular function	-
WDR82	80335	WD repeat domain 82	chromatin binding	Molecular function	-
G6PC2	57818	glucose-6-phosphatase, catalytic, 2	integral component of endoplasmic reticulum membrane	Cellular component	-
UCHL1	7345	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)	ligase activity	Molecular function	-
PDE4DIP	9659	phosphodiesterase 4D interacting protein	cellular protein complex assembly	Biological process	11134006
SBK1	388228	SH3 domain binding kinase 1	ATP binding	Molecular function	-
KIF21A	55605	kinesin family member 21A	microtubule motor activity	Molecular function	-
SLC4A5	57835	solute carrier family 4 (sodium bicarbonate cotransporter), member 5	transmembrane transport	Biological process	-
UBE2B	7320	ubiquitin-conjugating enzyme E2B	negative regulation of apoptotic process	Biological process	-
FKBP14	55033	FK506 binding protein 14, 22 kDa	endoplasmic reticulum membrane	Cellular component	-
CTGF	1490	connective tissue growth factor	protein binding	Molecular function	16457822
HLA-DQB2	3120	major histocompatibility complex, class II, DQ beta 2	endocytic vesicle membrane	Cellular component	-
CADM1	23705	cell adhesion molecule 1	PDZ domain binding	Molecular function	12826663
BRCA1	672	breast cancer 1, early onset	positive regulation of histone H3-K9 acetylation	Biological process	20820192
POFUT1	23509	protein O-fucosyltransferase 1	endoplasmic reticulum	Cellular component	15653671
HNRNPH2	3188	heterogeneous nuclear ribonucleoprotein H2 (H')	nucleoplasm	Cellular component	-
DTNBP1	84062	dystrobrevin binding protein 1	regulation of dopamine receptor signaling pathway	Biological process	-
PLCH1	23007	phospholipase C, eta 1	signal transducer activity	Molecular function	-
PLAU	5328	plasminogen activator, urokinase	signal transduction	Biological process	10749881
STAT3	6774	signal transducer and activator of transcription 3 (acute-phase response factor)	plasma membrane	Cellular component	-
PF4	5196	platelet factor 4	positive regulation of cAMP-mediated signaling	Biological process	12782716
ADD2	119	adducin 2 (beta)	actin cytoskeleton organization	Biological process	3693401
ELAC1	55520	elaC ribonuclease Z 1	nucleus	Cellular component	21593607
GABRR3	200959	gamma-aminobutyric acid (GABA) A receptor, rho 3 (gene/pseudogene)	ion transmembrane transport	Biological process	-
CCL3	6348	chemokine (C-C motif) ligand 3	eosinophil chemotaxis	Biological process	10072545
XRN1	54464	5'-3' exoribonuclease 1	membrane	Cellular component	19946888
RAC3	5881	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	regulation of small GTPase mediated signal transduction	Biological process	-
RAD9A	5883	RAD9 homolog A (S. pombe)	cellular response to DNA damage stimulus	Biological process	9872989
SMPD1	6609	sphingomyelin phosphodiesterase 1, acid lysosomal	glycosphingolipid metabolic process	Biological process	-
MITF	4286	microphthalmia-associated transcription factor	regulation of osteoclast differentiation	Biological process	-
VTI1A	143187	vesicle transport through interaction with t-SNAREs 1A	Golgi ribbon formation	Biological process	23677696
HSFY2	159119	heat shock transcription factor, Y linked 2	protein binding	Molecular function	25416956
PAPSS2	9060	3'-phosphoadenosine 5'-phosphosulfate synthase 2	bone development	Biological process	-
CNTN1	1272	contactin 1	Notch signaling pathway	Biological process	-
RALB	5899	v-ral simian leukemia viral oncogene homolog B	extracellular exosome	Cellular component	23376485
LMO2	4005	LIM domain only 2 (rhombotin-like 1)	protein binding	Molecular function	16189514
NFE2L2	4780	nuclear factor, erythroid 2-like 2	RNA polymerase II activating transcription factor binding	Molecular function	23043106
PLK2	10769	polo-like kinase 2	negative regulation of apoptotic process	Biological process	-
ACTR1A	10121	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)	dynactin complex	Cellular component	-
PRPF6	24148	pre-mRNA processing factor 6	spliceosomal tri-snRNP complex assembly	Biological process	15257298
ERMP1	79956	endoplasmic reticulum metallopeptidase 1	endoplasmic reticulum membrane	Cellular component	-
LIN7B	64130	lin-7 homolog B (C. elegans)	plasma membrane	Cellular component	-
ATP8B3	148229	ATPase, aminophospholipid transporter, class I, type 8B, member 3	magnesium ion binding	Molecular function	-
PRPF8	10594	pre-mRNA processing factor 8	RNA splicing	Biological process	9774689
RIMS1	22999	regulating synaptic membrane exocytosis 1	presynaptic membrane	Cellular component	11438518
STUB1	10273	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase	regulation of glucocorticoid metabolic process	Biological process	11146632
AGRN	375790	agrin	calcium ion binding	Molecular function	-
KIT	3815	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	detection of mechanical stimulus involved in sensory perception of sound	Biological process	-
ARFGAP2	84364	ADP-ribosylation factor GTPase activating protein 2	nucleolus	Cellular component	-
FOXA2	3170	forkhead box A2	primitive streak formation	Biological process	-
RAPGEF3	10411	Rap guanine nucleotide exchange factor (GEF) 3	positive regulation of syncytium formation by plasma membrane fusion	Biological process	23867755
CTNNA2	1496	catenin (cadherin-associated protein), alpha 2	muscle cell differentiation	Biological process	-
MTCH2	23788	mitochondrial carrier 2	regulation of mitochondrial membrane permeability involved in apoptotic process	Biological process	-
C11orf1	64776	chromosome 11 open reading frame 1	nucleoplasm	Cellular component	-
CCR7	1236	chemokine (C-C motif) receptor 7	intracellular	Cellular component	21051556
FANCD2	2177	Fanconi anemia, complementation group D2	Golgi apparatus	Cellular component	-
H2AFV	94239	H2A histone family, member V	nucleus	Cellular component	16457589
PTPMT1	114971	protein tyrosine phosphatase, mitochondrial 1	protein tyrosine phosphatase activity	Molecular function	-
CAV1	857	caveolin 1, caveolae protein, 22kDa	regulation of heart rate by cardiac conduction	Biological process	-
PCM1	5108	pericentriolar material 1	protein complex	Cellular component	24421332
FOXG1	2290	forkhead box G1	protein binding	Molecular function	12657635
PDPN	10630	podoplanin	lung alveolus development	Biological process	-
ATG4D	84971	autophagy related 4D, cysteine peptidase	C-terminal protein lipidation	Biological process	-
NR4A1	3164	nuclear receptor subfamily 4, group A, member 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	22427340
TNF	7124	tumor necrosis factor	positive regulation of interferon-gamma production	Biological process	-
NUP85	79902	nucleoporin 85kDa	cytokine-mediated signaling pathway	Biological process	-
LENG1	79165	leukocyte receptor cluster (LRC) member 1	protein binding	Molecular function	25416956
PSMD10	5716	proteasome (prosome, macropain) 26S subunit, non-ATPase, 10	nucleus	Cellular component	18040287
PRC1	9055	protein regulator of cytokinesis 1	identical protein binding	Molecular function	20691902
TICAM1	148022	toll-like receptor adaptor molecule 1	defense response to virus	Biological process	-
HSF2	3298	heat shock transcription factor 2	spermatogenesis	Biological process	-
COPB1	1315	coatomer protein complex, subunit beta 1	cytoplasm	Cellular component	-
CRTAC1	55118	cartilage acidic protein 1	olfactory bulb development	Biological process	-
CRH	1392	corticotropin releasing hormone	negative regulation of luteinizing hormone secretion	Biological process	-
NPLOC4	55666	nuclear protein localization 4 homolog (S. cerevisiae)	retrograde protein transport, ER to cytosol	Biological process	25660456
BDP1	55814	B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB	regulation of transcription from RNA polymerase III promoter	Biological process	-
PAPLN	89932	papilin, proteoglycan-like sulfated glycoprotein	serine-type endopeptidase inhibitor activity	Molecular function	-
FGFR2	2263	fibroblast growth factor receptor 2	angiogenesis	Biological process	-
DUSP28	285193	dual specificity phosphatase 28	JNK cascade	Biological process	-
AACS	65985	acetoacetyl-CoA synthetase	white fat cell differentiation	Biological process	-
OGG1	4968	8-oxoguanine DNA glycosylase	response to drug	Biological process	-
SLC4A5	57835	solute carrier family 4 (sodium bicarbonate cotransporter), member 5	cerebrospinal fluid secretion	Biological process	-
SRP68	6730	signal recognition particle 68kDa	signal recognition particle binding	Molecular function	17254600
PCK2	5106	phosphoenolpyruvate carboxykinase 2 (mitochondrial)	response to glucocorticoid	Biological process	-
PRMT8	56341	protein arginine methyltransferase 8	regulation of transcription, DNA-templated	Biological process	-
ADCY3	109	adenylate cyclase 3	metal ion binding	Molecular function	-
CASC5	57082	cancer susceptibility candidate 5	cytosol	Cellular component	-
HLA-DQA1	3117	major histocompatibility complex, class II, DQ alpha 1	MHC class II receptor activity	Molecular function	2300572
GYPA	2993	glycophorin A (MNS blood group)	external side of plasma membrane	Cellular component	-
NR1D2	9975	nuclear receptor subfamily 1, group D, member 2	intracellular receptor signaling pathway	Biological process	7997240
MOAP1	64112	modulator of apoptosis 1	positive regulation of apoptotic process	Biological process	15949439
ARRB2	409	arrestin, beta 2	positive regulation of synaptic transmission, dopaminergic	Biological process	-
ASNA1	439	arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)	transport	Biological process	9736449
TGFB3	7043	transforming growth factor, beta 3	lung alveolus development	Biological process	-
GCNT1	2650	glucosaminyl (N-acetyl) transferase 1, core 2	protein O-linked glycosylation	Biological process	-
TPM1	7168	tropomyosin 1 (alpha)	ventricular cardiac muscle tissue morphogenesis	Biological process	11136687
DHX36	170506	DEAH (Asp-Glu-Ala-His) box polypeptide 36	response to exogenous dsRNA	Biological process	-
DUOXA2	405753	dual oxidase maturation factor 2	endoplasmic reticulum membrane	Cellular component	-
AKR1B1	231	aldo-keto reductase family 1, member B1 (aldose reductase)	oxidation-reduction process	Biological process	-
CKLF	51192	chemokine-like factor	secretion by cell	Biological process	11415443
PTK2B	2185	protein tyrosine kinase 2 beta	cellular defense response	Biological process	-
TP53TG5	27296	TP53 target 5	nucleus	Cellular component	21630459
NPM1	4869	nucleophosmin (nucleolar phosphoprotein B23, numatrin)	nucleus	Cellular component	-
TNKS	8658	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase	protein polyubiquitination	Biological process	19759537
PIGA	5277	phosphatidylinositol glycan anchor biosynthesis, class A	membrane	Cellular component	19946888
SLC26A1	10861	solute carrier family 26 (anion exchanger), member 1	anion:anion antiporter activity	Molecular function	-
APP	351	amyloid beta (A4) precursor protein	protein binding	Molecular function	10049767
HJURP	55355	Holliday junction recognition protein	nucleoplasm	Cellular component	-
HAUS1	115106	HAUS augmin-like complex, subunit 1	HAUS complex	Cellular component	19369198
MYRIP	25924	myosin VIIA and Rab interacting protein	zinc ion binding	Molecular function	11964381
DSTYK	25778	dual serine/threonine and tyrosine protein kinase	protein tyrosine kinase activity	Molecular function	-
RNF216	54476	ring finger protein 216	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological process	19893624
EDN1	1906	endothelin 1	negative regulation of hormone secretion	Biological process	-
SMARCAL1	50485	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1	ATP binding	Molecular function	-
ERBB2	2064	erb-b2 receptor tyrosine kinase 2	positive regulation of transcription from RNA polymerase III promoter	Biological process	19372587
HCN4	10021	hyperpolarization activated cyclic nucleotide gated potassium channel 4	SA node cell action potential	Biological process	12750403
PPP2R5B	5526	protein phosphatase 2, regulatory subunit B', beta	endoplasmic reticulum unfolded protein response	Biological process	-
MYB	4602	v-myb avian myeloblastosis viral oncogene homolog	B cell differentiation	Biological process	-
SYNE2	23224	spectrin repeat containing, nuclear envelope 2	nuclear lumen	Cellular component	15671068
LTF	4057	lactotransferrin	iron ion binding	Molecular function	12037568
HLA-A	3105	major histocompatibility complex, class I, A	detection of bacterium	Biological process	22321387
COX17	10063	COX17 cytochrome c oxidase copper chaperone	heart development	Biological process	-
MTPAP	55149	mitochondrial poly(A) polymerase	mitochondrion	Cellular component	-
TGFB2	7042	transforming growth factor, beta 2	cartilage condensation	Biological process	-
SDC2	6383	syndecan 2	response to hypoxia	Biological process	-
AZI2	64343	5-azacytidine induced 2	interleukin-6 production	Biological process	-
GRHL3	57822	grainyhead-like 3 (Drosophila)	cochlea morphogenesis	Biological process	-
ODF1	4956	outer dense fiber of sperm tails 1	spermatogenesis	Biological process	-
TFAM	7019	transcription factor A, mitochondrial	mitochondrial matrix	Cellular component	-
ABAT	18	4-aminobutyrate aminotransferase	extracellular exosome	Cellular component	23376485
FGF7	2252	fibroblast growth factor 7	protein binding	Molecular function	1309608
PSMG1	8624	proteasome (prosome, macropain) assembly chaperone 1	protein binding	Molecular function	16251969
GNG7	2788	guanine nucleotide binding protein (G protein), gamma 7	G-protein coupled receptor signaling pathway	Biological process	-
E4F1	1877	E4F transcription factor 1	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	-
RAB10	10890	RAB10, member RAS oncogene family	endosomal transport	Biological process	16641372
GGT1	2678	gamma-glutamyltransferase 1	gamma-glutamyltransferase activity	Molecular function	18357469
SRSF10	10772	serine/arginine-rich splicing factor 10	cytoplasm	Cellular component	11684676
CIDEB	27141	cell death-inducing DFFA-like effector b	positive regulation of release of cytochrome c from mitochondria	Biological process	12595532
NGB	58157	neuroglobin	protein binding	Molecular function	25416956
HIST1H2BN	8341	histone cluster 1, H2bn	DNA binding	Molecular function	9439656
WNT5A	7474	wingless-type MMTV integration site family, member 5A	positive regulation of thymocyte apoptotic process	Biological process	-
EIF4EBP1	1978	eukaryotic translation initiation factor 4E binding protein 1	negative regulation of translational initiation	Biological process	22578813
GCN1L1	10985	GCN1 general control of amino-acid synthesis 1-like 1 (yeast)	membrane	Cellular component	19946888
JAGN1	84522	jagunal homolog 1 (Drosophila)	protein binding	Molecular function	25416956
OLIG2	10215	oligodendrocyte lineage transcription factor 2	myelination	Biological process	-
SRPX2	27286	sushi-repeat containing protein, X-linked 2	cell motility	Biological process	19065654
HAPLN2	60484	hyaluronan and proteoglycan link protein 2	extracellular matrix assembly	Biological process	-
DMD	1756	dystrophin	positive regulation of sodium ion transmembrane transporter activity	Biological process	21677768
SNCA	6622	synuclein, alpha (non A4 component of amyloid precursor)	oxidation-reduction process	Biological process	21320589
EGFR	1956	epidermal growth factor receptor	apical plasma membrane	Cellular component	-
TMEM248	55069	transmembrane protein 248	protein binding	Molecular function	25416956
GLT6D1	360203	glycosyltransferase 6 domain containing 1	transferase activity, transferring hexosyl groups	Molecular function	-
ZNF774	342132	zinc finger protein 774	protein binding	Molecular function	25416956
UQCRC2	7385	ubiquinol-cytochrome c reductase core protein II	mitochondrial respiratory chain complex III	Cellular component	-
DNAH10	196385	dynein, axonemal, heavy chain 10	metabolic process	Biological process	-
SHANK2	22941	SH3 and multiple ankyrin repeat domains 2	memory	Biological process	-
SESN1	27244	sestrin 1	negative regulation of cell proliferation	Biological process	9926927
CLASP2	23122	cytoplasmic linker associated protein 2	membrane	Cellular component	19946888
USP3	9960	ubiquitin specific peptidase 3	mitotic cell cycle	Biological process	17980597
EGFR	1956	epidermal growth factor receptor	regulation of nitric-oxide synthase activity	Biological process	12828935
NKD1	85407	naked cuticle homolog 1 (Drosophila)	protein binding	Molecular function	15687260
TAF7	6879	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa	DNA-templated transcription, initiation	Biological process	9603525
THBS1	7057	thrombospondin 1	immune response	Biological process	18674744
RRM2	6241	ribonucleotide reductase M2	nucleobase-containing small molecule interconversion	Biological process	-
RFC4	5984	replication factor C (activator 1) 4, 37kDa	telomere maintenance	Biological process	-
TTN	7273	titin	cardiac muscle fiber development	Biological process	9817758
HMG20A	10363	high mobility group 20A	protein heterodimerization activity	Molecular function	-
ACVRL1	94	activin A receptor type II-like 1	positive regulation of angiogenesis	Biological process	-
CCNB2	9133	cyclin B2	protein binding	Molecular function	15232106
CASP8	841	caspase 8, apoptosis-related cysteine peptidase	cellular response to mechanical stimulus	Biological process	19593445
CCR5	1234	chemokine (C-C motif) receptor 5 (gene/pseudogene)	cell surface receptor signaling pathway	Biological process	8639485
TWIST1	7291	twist family bHLH transcription factor 1	embryonic camera-type eye formation	Biological process	17070479
VEGFB	7423	vascular endothelial growth factor B	positive regulation of peptidyl-tyrosine phosphorylation	Biological process	11122379
GLS	2744	glutaminase	synaptic transmission	Biological process	-
RAPGEF1	2889	Rap guanine nucleotide exchange factor (GEF) 1	negative regulation of protein kinase B signaling	Biological process	-
PRKAB2	5565	protein kinase, AMP-activated, beta 2 non-catalytic subunit	protein binding	Molecular function	16306228
SMARCD1	6602	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	chromatin-mediated maintenance of transcription	Biological process	12917342
NLRP3	114548	NLR family, pyrin domain containing 3	defense response to virus	Biological process	-
CPT2	1376	carnitine palmitoyltransferase 2	nucleolus	Cellular component	-
IFT81	28981	intraflagellar transport 81	sperm principal piece	Cellular component	-
PPP4R2	151987	protein phosphatase 4, regulatory subunit 2	regulation of catalytic activity	Biological process	20154705
DUSP15	128853	dual specificity phosphatase 15	transforming growth factor beta receptor signaling pathway	Biological process	-
OSGIN1	29948	oxidative stress induced growth inhibitor 1	negative regulation of cell growth	Biological process	11459809
H2AFY	9555	H2A histone family, member Y	positive regulation of gene expression, epigenetic	Biological process	25526730
NPTN	27020	neuroplastin	cell adhesion molecule binding	Molecular function	-
CNBP	7555	CCHC-type zinc finger, nucleic acid binding protein	protein binding	Molecular function	24726729
CDC5L	988	cell division cycle 5-like	mRNA splicing, via spliceosome	Biological process	-
ME2	4200	malic enzyme 2, NAD(+)-dependent, mitochondrial	intracellular membrane-bounded organelle	Cellular component	-
TRIM36	55521	tripartite motif containing 36	ligase activity	Molecular function	-
ZNF292	23036	zinc finger protein 292	transcription, DNA-templated	Biological process	-
COPS5	10987	COP9 signalosome subunit 5	transcription from RNA polymerase II promoter	Biological process	8837781
RPL14	9045	ribosomal protein L14	cytoplasm	Cellular component	-
NPFF	8620	neuropeptide FF-amide peptide precursor	neuropeptide signaling pathway	Biological process	-
LIF	3976	leukemia inhibitory factor	regulation of metanephric nephron tubule epithelial cell differentiation	Biological process	20624457
CMC1	152100	C-x(9)-C motif containing 1	mitochondrion	Cellular component	-
RAP2A	5911	RAP2A, member of RAS oncogene family	actin cytoskeleton reorganization	Biological process	15342639
BRE	9577	brain and reproductive organ-expressed (TNFRSF1A modulator)	peroxisome targeting sequence binding	Molecular function	11676476
SPESP1	246777	sperm equatorial segment protein 1	fusion of sperm to egg plasma membrane	Biological process	-
SPAST	6683	spastin	cytoplasm	Cellular component	16026783
TRIM31	11074	tripartite motif containing 31	protein binding	Molecular function	16189514
CLDN14	23562	claudin 14	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules	Biological process	-
GTF3C5	9328	general transcription factor IIIC, polypeptide 5, 63kDa	transcription, DNA-templated	Biological process	17409385
GATA6	2627	GATA binding protein 6	positive regulation of angiogenesis	Biological process	21127043
DCX	1641	doublecortin	dendrite morphogenesis	Biological process	-
INSR	3643	insulin receptor	epidermis development	Biological process	-
ZNF645	158506	zinc finger protein 645	regulation of cell adhesion	Biological process	-
MST1	4485	macrophage stimulating 1	proteolysis	Biological process	-
MAP3K4	4216	mitogen-activated protein kinase kinase kinase 4	positive regulation of p38MAPK cascade	Biological process	9305639
GFI1	2672	growth factor independent 1 transcription repressor	negative regulation of cell fate specification	Biological process	-
KATNA1	11104	katanin p60 (ATPase containing) subunit A 1	cell division	Biological process	-
GMNN	51053	geminin, DNA replication inhibitor	organ morphogenesis	Biological process	-
KIF14	9928	kinesin family member 14	microtubule	Cellular component	23209302
DCXR	51181	dicarbonyl/L-xylulose reductase	extracellular exosome	Cellular component	19056867
CCT7	10574	chaperonin containing TCP1, subunit 7 (eta)	cytosol	Cellular component	-
NANOG	79923	Nanog homeobox	regulation of gene expression	Biological process	18388306
ZKSCAN1	7586	zinc finger with KRAB and SCAN domains 1	sequence-specific DNA binding transcription factor activity	Molecular function	7557990
VWF	7450	von Willebrand factor	hemostasis	Biological process	10887119
HSF4	3299	heat shock transcription factor 4	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
ABCC8	6833	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	ATPase activity, coupled to transmembrane movement of substances	Molecular function	-
PTMS	5763	parathymosin	DNA replication	Biological process	10854063
KCNK3	3777	potassium channel, two pore domain subfamily K, member 3	protein C-terminus binding	Molecular function	-
HIST1H4J	8363	histone cluster 1, H4j	DNA binding	Molecular function	3035717
PAX6	5080	paired box 6	interkinetic nuclear migration	Biological process	-
PITPNM2	57605	phosphatidylinositol transfer protein, membrane-associated 2	endomembrane system	Cellular component	-
ELL	8178	elongation factor RNA polymerase II	protein binding	Molecular function	19389623
BRD4	23476	bromodomain containing 4	regulation of phosphorylation of RNA polymerase II C-terminal domain	Biological process	23086925
HIST1H4H	8365	histone cluster 1, H4h	protein complex	Cellular component	14718166
GRASP	160622	GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein	cell junction	Cellular component	-
TUBGCP2	10844	tubulin, gamma complex associated protein 2	cytoplasmic microtubule	Cellular component	9566967
GHRH	2691	growth hormone releasing hormone	positive regulation of circadian sleep/wake cycle, REM sleep	Biological process	18329818
LRRFIP1	9208	leucine rich repeat (in FLII) interacting protein 1	biological_process	Biological process	-
RIPK1	8737	receptor (TNFRSF)-interacting serine-threonine kinase 1	activation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	-
ADCY7	113	adenylate cyclase 7	adenylate cyclase activity	Molecular function	11113152
PRSS16	10279	protease, serine, 16 (thymus)	lysosome	Cellular component	10527559
FFAR3	2865	free fatty acid receptor 3	inflammatory response	Biological process	-
PROC	5624	protein C (inactivator of coagulation factors Va and VIIIa)	negative regulation of apoptotic process	Biological process	12563316
LRP1	4035	low density lipoprotein receptor-related protein 1	nucleolus	Cellular component	-
PBX2	5089	pre-B-cell leukemia homeobox 2	transcription factor complex	Cellular component	-
TAF13	6884	TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa	transcription initiation from RNA polymerase II promoter	Biological process	-
SKI	6497	SKI proto-oncogene	protein domain specific binding	Molecular function	11441023
GART	2618	phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase	methyltransferase activity	Molecular function	-
ZNF833P	401898	zinc finger protein 833, pseudogene	metal ion binding	Molecular function	-
COL4A3	1285	collagen, type IV, alpha 3 (Goodpasture antigen)	endothelial cell apoptotic process	Biological process	10766752
PRMT7	54496	protein arginine methyltransferase 7	protein-arginine omega-N asymmetric methyltransferase activity	Molecular function	-
BPGM	669	2,3-bisphosphoglycerate mutase	bisphosphoglycerate 2-phosphatase activity	Molecular function	-
HIST3H2BB	128312	histone cluster 3, H2bb	molecular_function	Molecular function	-
RPS2	6187	ribosomal protein S2	fibroblast growth factor binding	Molecular function	16263090
UCN2	90226	urocortin 2	extracellular region	Cellular component	11329063
ZFP36	7538	ZFP36 ring finger protein	single-stranded RNA binding	Molecular function	9703499
PRAMEF7	441871	PRAME family member 7	negative regulation of retinoic acid receptor signaling pathway	Biological process	-
OR2A4	79541	olfactory receptor, family 2, subfamily A, member 4	olfactory receptor activity	Molecular function	-
THOC1	9984	THO complex 1	mRNA export from nucleus	Biological process	22144908
SERPINE2	5270	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2	negative regulation of endopeptidase activity	Biological process	-
RPL5	6125	ribosomal protein L5	viral life cycle	Biological process	-
FKBP8	23770	FK506 binding protein 8, 38kDa	metal ion binding	Molecular function	-
NTRK2	4915	neurotrophic tyrosine kinase, receptor, type 2	cell surface	Cellular component	-
FIZ1	84922	FLT3-interacting zinc finger 1	regulation of transcription, DNA-templated	Biological process	-
ZNF226	7769	zinc finger protein 226	regulation of transcription, DNA-templated	Biological process	-
PTPRC	5788	protein tyrosine phosphatase, receptor type, C	transmembrane receptor protein tyrosine phosphatase activity	Molecular function	2845400
TNF	7124	tumor necrosis factor	activation of MAPK activity	Biological process	10748004
PRDM13	59336	PR domain containing 13	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
EPHX2	2053	epoxide hydrolase 2, cytoplasmic	magnesium ion binding	Molecular function	12574510
MGST1	4257	microsomal glutathione S-transferase 1	protein homotrimerization	Biological process	-
CH25H	9023	cholesterol 25-hydroxylase	oxidation-reduction process	Biological process	-
GUCY2F	2986	guanylate cyclase 2F, retinal	receptor guanylyl cyclase signaling pathway	Biological process	7777544
KIAA1919	91749	KIAA1919	integral component of membrane	Cellular component	-
RBM33	155435	RNA binding motif protein 33	poly(A) RNA binding	Molecular function	22658674
ZC3H12A	80149	zinc finger CCCH-type containing 12A	positive regulation of autophagy	Biological process	22739135
FLOT1	10211	flotillin 1	response to endoplasmic reticulum stress	Biological process	25204797
PDGFRB	5159	platelet-derived growth factor receptor, beta polypeptide	protein kinase binding	Molecular function	16479011
UBE2L3	7332	ubiquitin-conjugating enzyme E2L 3	protein binding	Molecular function	10888878
TNXB	7148	tenascin XB	cell adhesion	Biological process	-
PRUNE2	158471	prune homolog 2 (Drosophila)	metal ion binding	Molecular function	-
CYR61	3491	cysteine-rich, angiogenic inducer, 61	atrioventricular valve morphogenesis	Biological process	-
MYH10	4628	myosin, heavy chain 10, non-muscle	stress fiber	Cellular component	15774463
CKAP2L	150468	cytoskeleton associated protein 2-like	cytoplasm	Cellular component	-
ELOVL7	79993	ELOVL fatty acid elongase 7	endoplasmic reticulum membrane	Cellular component	-
CDC23	8697	cell division cycle 23	regulation of exit from mitosis	Biological process	9790767
TEC	7006	tec protein tyrosine kinase	adaptive immune response	Biological process	-
CYP1A1	1543	cytochrome P450, family 1, subfamily A, polypeptide 1	response to immobilization stress	Biological process	-
NAMPT	10135	nicotinamide phosphoribosyltransferase	positive regulation of transcription from RNA polymerase II promoter	Biological process	23001182
NOXRED1	122945	NADP-dependent oxidoreductase domain containing 1	proline biosynthetic process	Biological process	-
TBC1D12	23232	TBC1 domain family, member 12	GTPase activator activity	Molecular function	-
DUSP5	1847	dual specificity phosphatase 5	MAP kinase tyrosine/serine/threonine phosphatase activity	Molecular function	-
SLC9A3R1	9368	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1	regulation of sodium:proton antiporter activity	Biological process	9560162
MED1	5469	mediator complex subunit 1	sequence-specific DNA binding RNA polymerase II transcription factor activity	Molecular function	-
C10orf99	387695	chromosome 10 open reading frame 99	negative regulation of cell division	Biological process	25351403
PSG6	5675	pregnancy specific beta-1-glycoprotein 6	extracellular region	Cellular component	2271648
PSEN1	5663	presenilin 1	endoplasmic reticulum	Cellular component	15274632
NR5A1	2516	nuclear receptor subfamily 5, group A, member 1	transcription coactivator activity	Molecular function	8205615
SPRY2	10253	sprouty homolog 2 (Drosophila)	protein kinase binding	Molecular function	20736167
IL2RA	3559	interleukin 2 receptor, alpha	interleukin-2 receptor activity	Molecular function	-
BUB1	699	BUB1 mitotic checkpoint serine/threonine kinase	protein binding	Molecular function	10198256
HLA-DMA	3108	major histocompatibility complex, class II, DM alpha	MHC class II protein complex binding	Molecular function	22733780
BTC	685	betacellulin	intracellular	Cellular component	-
PGF	5228	placental growth factor	cell differentiation	Biological process	-
CHCHD3	54927	coiled-coil-helix-coiled-coil-helix domain containing 3	extracellular exosome	Cellular component	19056867
SF3B5	83443	splicing factor 3b, subunit 5, 10kDa	gene expression	Biological process	-
MSX2	4488	msh homeobox 2	cellular response to estradiol stimulus	Biological process	-
DDX49	54555	DEAD (Asp-Glu-Ala-Asp) box polypeptide 49	ATP-dependent RNA helicase activity	Molecular function	-
CCNF	899	cyclin F	re-entry into mitotic cell cycle	Biological process	-
CBLN1	869	cerebellin 1 precursor	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	Biological process	-
ADAMTSL5	339366	ADAMTS-like 5	heparin binding	Molecular function	23010571
GMFB	2764	glia maturation factor, beta	learning	Biological process	-
HDAC4	9759	histone deacetylase 4	cytoplasm	Cellular component	-
FASLG	356	Fas ligand (TNF superfamily, member 6)	integral component of plasma membrane	Cellular component	7826947
CDH19	28513	cadherin 19, type 2	plasma membrane	Cellular component	-
CHRDL1	91851	chordin-like 1	compound eye development	Biological process	22284829
VAT1	10493	vesicle amine transport 1	oxidation-reduction process	Biological process	-
CLCN3	1182	chloride channel, voltage-sensitive 3	volume-sensitive chloride channel activity	Molecular function	12183454
PSMA5	5686	proteasome (prosome, macropain) subunit, alpha type, 5	regulation of apoptotic process	Biological process	-
STK24	8428	serine/threonine kinase 24	cytosol	Cellular component	-
RELL1	768211	RELT-like 1	integral component of membrane	Cellular component	-
AGO1	26523	argonaute RISC catalytic component 1	protein binding	Molecular function	12526743
XPA	7507	xeroderma pigmentosum, complementation group A	metal ion binding	Molecular function	-
GPR171	29909	G protein-coupled receptor 171	integral component of membrane	Cellular component	9370294
NELFE	7936	negative elongation factor complex member E	negative regulation of mRNA polyadenylation	Biological process	19575011
TRNT1	51095	tRNA nucleotidyl transferase, CCA-adding, 1	mitochondrion	Cellular component	-
CHRNA9	55584	cholinergic receptor, nicotinic, alpha 9 (neuronal)	cytosol	Cellular component	18420419
PEX3	8504	peroxisomal biogenesis factor 3	protein dimerization activity	Molecular function	19715730
BCAM	4059	basal cell adhesion molecule (Lutheran blood group)	laminin receptor activity	Molecular function	16236823
SCAMP3	10067	secretory carrier membrane protein 3	ubiquitin protein ligase binding	Molecular function	23418353
SLC39A2	29986	solute carrier family 39 (zinc transporter), member 2	zinc II ion transport	Biological process	10681536
FLVCR1	28982	feline leukemia virus subgroup C cellular receptor 1	in utero embryonic development	Biological process	-
MAP1LC3C	440738	microtubule-associated protein 1 light chain 3 gamma	autophagosome	Cellular component	12740394
CELF2	10659	CUGBP, Elav-like family member 2	nucleotide binding	Molecular function	-
IZUMO1	284359	izumo sperm-egg fusion 1	protein homodimerization activity	Molecular function	-
NR2E3	10002	nuclear receptor subfamily 2, group E, member 3	transcription from RNA polymerase II promoter	Biological process	10220376
KIR2DS4	3809	killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4	innate immune response	Biological process	-
HNF1A	6927	HNF1 homeobox A	protein homodimerization activity	Molecular function	1677179
FST	10468	follistatin	keratinocyte proliferation	Biological process	-
MAN1B1	11253	mannosidase, alpha, class 1B, member 1	cellular protein metabolic process	Biological process	-
SNAI2	6591	snail family zinc finger 2	nucleus	Cellular component	10866665
TGM3	7053	transglutaminase 3	extracellular exosome	Cellular component	19199708
CCL2	6347	chemokine (C-C motif) ligand 2	extracellular space	Cellular component	-
GIPR	2696	gastric inhibitory polypeptide receptor	endocrine pancreas development	Biological process	-
THPO	7066	thrombopoietin	positive regulation of protein kinase B signaling	Biological process	-
ELOVL3	83401	ELOVL fatty acid elongase 3	long-chain fatty-acyl-CoA biosynthetic process	Biological process	-
CAMK1D	57118	calcium/calmodulin-dependent protein kinase ID	calmodulin-dependent protein kinase activity	Molecular function	-
CRISPLD1	83690	cysteine-rich secretory protein LCCL domain containing 1	molecular_function	Molecular function	-
ADCY4	196883	adenylate cyclase 4	epidermal growth factor receptor signaling pathway	Biological process	-
HAS1	3036	hyaluronan synthase 1	extracellular matrix assembly	Biological process	-
CEACAM7	1087	carcinoembryonic antigen-related cell adhesion molecule 7	plasma membrane	Cellular component	-
ENSA	2029	endosulfine alpha	response to glucose	Biological process	-
CRABP1	1381	cellular retinoic acid binding protein 1	signal transduction	Biological process	1309505
CTNNA2	1496	catenin (cadherin-associated protein), alpha 2	structural constituent of cytoskeleton	Molecular function	8432524
FOXN4	121643	forkhead box N4	sequence-specific DNA binding transcription factor activity	Molecular function	-
WNT11	7481	wingless-type MMTV integration site family, member 11	frizzled binding	Molecular function	-
SAP30BP	29115	SAP30 binding protein	nucleoplasm	Cellular component	-
APBB2	323	amyloid beta (A4) precursor protein-binding, family B, member 2	neuron migration	Biological process	-
ZNF311	282890	zinc finger protein 311	sequence-specific DNA binding transcription factor activity	Molecular function	-
TRPC3	7222	transient receptor potential cation channel, subfamily C, member 3	positive regulation of cardiac muscle hypertrophy in response to stress	Biological process	19287093
ICE2	79664	interactor of little elongation complex ELL subunit 2	transcription elongation factor complex	Cellular component	22195968
MKRN1	23608	makorin ring finger protein 1	poly(A) RNA binding	Molecular function	22658674
DCLK2	166614	doublecortin-like kinase 2	ATP binding	Molecular function	-
TYR	7299	tyrosinase	integral component of membrane	Cellular component	-
STAB2	55576	stabilin 2	carbohydrate metabolic process	Biological process	-
NOTO	344022	notochord homeobox	dorsal/ventral pattern formation	Biological process	-
FAM110C	642273	family with sequence similarity 110, member C	alpha-tubulin binding	Molecular function	19698782
DCUN1D5	84259	DCN1, defective in cullin neddylation 1, domain containing 5	biological_process	Biological process	-
BTRC	8945	beta-transducin repeat containing E3 ubiquitin protein ligase	branching involved in mammary gland duct morphogenesis	Biological process	-
CLTC	1213	clathrin, heavy chain (Hc)	clathrin coat	Cellular component	1765375
PM20D2	135293	peptidase M20 domain containing 2	nucleoplasm	Cellular component	-
ZAK	51776	sterile alpha motif and leucine zipper containing kinase AZK	nucleus	Cellular component	-
JADE3	9767	jade family PHD finger 3	histone acetyltransferase complex	Cellular component	16387653
PSMC1	5700	proteasome (prosome, macropain) 26S subunit, ATPase, 1	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
KRT18	3875	keratin 18, type I	cell periphery	Cellular component	-
ANAPC10	10393	anaphase promoting complex subunit 10	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
EIF1AX	1964	eukaryotic translation initiation factor 1A, X-linked	protein binding	Molecular function	21139563
PARVG	64098	parvin, gamma	focal adhesion	Cellular component	-
TRAPPC1	58485	trafficking protein particle complex 1	TRAPP complex	Cellular component	-
BAIAP3	8938	BAI1-associated protein 3	G-protein coupled receptor signaling pathway	Biological process	9790924
BIRC8	112401	baculoviral IAP repeat containing 8	inhibition of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	-
PRKAR2A	5576	protein kinase, cAMP-dependent, regulatory, type II, alpha	cAMP binding	Molecular function	-
G6PD	2539	glucose-6-phosphate dehydrogenase	erythrocyte maturation	Biological process	5643703
FXYD5	53827	FXYD domain containing ion transport regulator 5	negative regulation of calcium-dependent cell-cell adhesion	Biological process	11756660
KLK8	11202	kallikrein-related peptidase 8	memory	Biological process	-
PTMS	5763	parathymosin	immune system process	Biological process	-
CABP4	57010	calcium binding protein 4	signal transduction	Biological process	10625670
STRA6	64220	stimulated by retinoic acid 6	artery morphogenesis	Biological process	17273977
PDE8B	8622	phosphodiesterase 8B	3',5'-cyclic-nucleotide phosphodiesterase activity	Molecular function	9784418
PIANP	196500	PILR alpha associated neural protein	integral component of membrane	Cellular component	-
GLI1	2735	GLI family zinc finger 1	ventral midline development	Biological process	-
COX11	1353	COX11 cytochrome c oxidase copper chaperone	respiratory gaseous exchange	Biological process	9878253
PEX5	5830	peroxisomal biogenesis factor 5	protein import into peroxisome matrix, docking	Biological process	21976670
HADH	3033	hydroxyacyl-CoA dehydrogenase	cellular lipid metabolic process	Biological process	-
LRRTM2	26045	leucine rich repeat transmembrane neuronal 2	postsynaptic membrane	Cellular component	-
COL10A1	1300	collagen, type X, alpha 1	cartilage development	Biological process	-
TNFSF18	8995	tumor necrosis factor (ligand) superfamily, member 18	T cell proliferation involved in immune response	Biological process	-
FGFR2	2263	fibroblast growth factor receptor 2	epidermis morphogenesis	Biological process	-
MRAP	56246	melanocortin 2 receptor accessory protein	positive regulation of cAMP biosynthetic process	Biological process	19329486
ZNF337	26152	zinc finger protein 337	regulation of transcription, DNA-templated	Biological process	-
PFDN2	5202	prefoldin subunit 2	extracellular exosome	Cellular component	23376485
SLC9A9	285195	solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9	late endosome membrane	Cellular component	-
GALR1	2587	galanin receptor 1	galanin receptor activity	Molecular function	24517231
GOT1	2805	glutamic-oxaloacetic transaminase 1, soluble	L-cysteine:2-oxoglutarate aminotransferase activity	Molecular function	-
DDX23	9416	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23	extracellular exosome	Cellular component	19199708
LONRF1	91694	LON peptidase N-terminal domain and ring finger 1	protein binding	Molecular function	19549727
MAP6D1	79929	MAP6 domain containing 1	microtubule binding	Molecular function	-
ARHGAP11A	9824	Rho GTPase activating protein 11A	positive regulation of GTPase activity	Biological process	-
RBPJL	11317	recombination signal binding protein for immunoglobulin kappa J region-like	signal transduction	Biological process	9929984
IGHM	3507	immunoglobulin heavy constant mu	adaptive immune response	Biological process	21786026
CLK3	1198	CDC-like kinase 3	protein phosphorylation	Biological process	9637771
IPO8	10526	importin 8	gene expression	Biological process	-
ATG9A	79065	autophagy related 9A	late endosome	Cellular component	22456507
ATP5C1	509	ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1	mitochondrial ATP synthesis coupled proton transport	Biological process	-
KDM4C	23081	lysine (K)-specific demethylase 4C	small GTPase mediated signal transduction	Biological process	-
MLYCD	23417	malonyl-CoA decarboxylase	mitochondrion	Cellular component	10417274
XRCC1	7515	X-ray repair complementing defective repair in Chinese hamster cells 1	response to organic substance	Biological process	-
ADIPOQ	9370	adiponectin, C1Q and collagen domain containing	protein heterotrimerization	Biological process	-
TCEB2	6923	transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)	extracellular exosome	Cellular component	23376485
TMEM64	169200	transmembrane protein 64	positive regulation of bone resorption	Biological process	-
UBE2G2	7327	ubiquitin-conjugating enzyme E2G 2	cytosol	Cellular component	16780588
DAO	1610	D-amino-acid oxidase	cellular nitrogen compound metabolic process	Biological process	-
SOD1	6647	superoxide dismutase 1, soluble	copper ion binding	Molecular function	17008312
EBP	10682	emopamil binding protein (sterol isomerase)	cholesterol metabolic process	Biological process	10391219
G6PC3	92579	glucose 6 phosphatase, catalytic, 3	integral component of endoplasmic reticulum membrane	Cellular component	-
WDR3	10885	WD repeat domain 3	small-subunit processome	Cellular component	-
LAMP2	3920	lysosomal-associated membrane protein 2	phagocytic vesicle membrane	Cellular component	-
SLC16A13	201232	solute carrier family 16, member 13	integral component of membrane	Cellular component	-
HSP90B1	7184	heat shock protein 90kDa beta (Grp94), member 1	response to hypoxia	Biological process	15620698
UBIAD1	29914	UbiA prenyltransferase domain containing 1	cytoplasm	Cellular component	11314041
ZDHHC8	29801	zinc finger, DHHC-type containing 8	cytoplasmic vesicle membrane	Cellular component	-
HEY1	23462	hes-related family bHLH transcription factor with YRPW motif 1	umbilical cord morphogenesis	Biological process	-
SLC9A9	285195	solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9	protein binding	Molecular function	24705354
ARFGEF1	10565	ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)	nucleoplasm	Cellular component	-
AVPR2	554	arginine vasopressin receptor 2	hemostasis	Biological process	10880054
STAB2	55576	stabilin 2	low-density lipoprotein receptor activity	Molecular function	12077138
TMEM231	79583	transmembrane protein 231	cilium assembly	Biological process	-
NFATC4	4776	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	transcription coactivator activity	Molecular function	7749981
PFN3	345456	profilin 3	cytoskeleton	Cellular component	-
SEMA4D	10507	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	transmembrane signaling receptor activity	Molecular function	20877282
SLC1A7	6512	solute carrier family 1 (glutamate transporter), member 7	L-glutamate transmembrane transporter activity	Molecular function	9108121
CCDC22	28952	coiled-coil domain containing 22	cullin family protein binding	Molecular function	23563313
CRTC1	23373	CREB regulated transcription coactivator 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	14536081
ADGRG1	9289	adhesion G protein-coupled receptor G1	layer formation in cerebral cortex	Biological process	-
ADI1	55256	acireductone dioxygenase 1	oxidoreductase activity	Molecular function	15938715
ZNF76	7629	zinc finger protein 76	regulation of transcription from RNA polymerase II promoter	Biological process	9705341
NCF1	653361	neutrophil cytosolic factor 1	antigen processing and presentation of exogenous peptide antigen via MHC class I	Biological process	-
FOXC2	2303	forkhead box C2	mesoderm development	Biological process	8674414
PAF1	54623	Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)	negative regulation of myeloid cell differentiation	Biological process	20541477
MSH2	4436	mutS homolog 2	determination of adult lifespan	Biological process	-
TRIM63	84676	tripartite motif containing 63, E3 ubiquitin protein ligase	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological process	-
TRAF6	7189	TNF receptor-associated factor 6, E3 ubiquitin protein ligase	mitogen-activated protein kinase kinase kinase binding	Molecular function	10094049
PRKACA	5566	protein kinase, cAMP-dependent, catalytic, alpha	calcium-mediated signaling using intracellular calcium source	Biological process	23507255
UBB	7314	ubiquitin B	MyD88-dependent toll-like receptor signaling pathway	Biological process	-
SKIL	6498	SKI-like proto-oncogene	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage	Biological process	-
EFS	10278	embryonal Fyn-associated substrate	cell adhesion	Biological process	-
BRSK2	9024	BR serine/threonine kinase 2	regulation of insulin secretion involved in cellular response to glucose stimulus	Biological process	-
TRPM2	7226	transient receptor potential cation channel, subfamily M, member 2	ion transmembrane transport	Biological process	-
SOX2	6657	SRY (sex determining region Y)-box 2	eye development	Biological process	18285410
CIB1	10519	calcium and integrin binding 1 (calmyrin)	negative regulation of protein kinase B signaling	Biological process	-
DNAJC10	54431	DnaJ (Hsp40) homolog, subfamily C, member 10	oxidation-reduction process	Biological process	-
IL13	3596	interleukin 13	protein binding	Molecular function	18243101
PABPC1L2A	340529	poly(A) binding protein, cytoplasmic 1-like 2A	RNA binding	Molecular function	-
RTF1	23168	Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	positive regulation of histone H3-K4 methylation	Biological process	-
MERTK	10461	MER proto-oncogene, tyrosine kinase	positive regulation of phagocytosis	Biological process	18395422
PCDHGB6	56100	protocadherin gamma subfamily B, 6	plasma membrane	Cellular component	-
CLK3	1198	CDC-like kinase 3	ATP binding	Molecular function	-
TRAF3	7187	TNF receptor-associated factor 3	endosome	Cellular component	-
GMFB	2764	glia maturation factor, beta	locomotory behavior	Biological process	-
UGT1A6	54578	UDP glucuronosyltransferase 1 family, polypeptide A6	flavonoid glucuronidation	Biological process	-
SPTBN4	57731	spectrin, beta, non-erythrocytic 4	cytoplasm	Cellular component	-
APP	351	amyloid beta (A4) precursor protein	serine-type endopeptidase inhibitor activity	Molecular function	10652580
RPLP2	6181	ribosomal protein, large, P2	membrane	Cellular component	19946888
PTPRC	5788	protein tyrosine phosphatase, receptor type, C	positive regulation of antigen receptor-mediated signaling pathway	Biological process	-
MYO1F	4542	myosin IF	negative regulation of cell adhesion	Biological process	-
PTK6	5753	protein tyrosine kinase 6	innate immune response	Biological process	-
TRPC3	7222	transient receptor potential cation channel, subfamily C, member 3	cytosol	Cellular component	-
MYO6	4646	myosin VI	membrane	Cellular component	19946888
ACIN1	22985	apoptotic chromatin condensation inducer 1	nucleolus	Cellular component	-
DNAJC17	55192	DnaJ (Hsp40) homolog, subfamily C, member 17	toxin transport	Biological process	-
KDM1A	23028	lysine (K)-specific demethylase 1A	positive regulation of megakaryocyte differentiation	Biological process	-
RPS27A	6233	ribosomal protein S27a	extracellular exosome	Cellular component	19199708
HELZ	9931	helicase with zinc finger	metabolic process	Biological process	-
OR9A4	130075	olfactory receptor, family 9, subfamily A, member 4	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
PLN	5350	phospholamban	blood circulation	Biological process	8406504
NEGR1	257194	neuronal growth regulator 1	positive regulation of neuron projection development	Biological process	-
SUCLG2	8801	succinate-CoA ligase, GDP-forming, beta subunit	succinyl-CoA metabolic process	Biological process	9765291
PCP2	126006	Purkinje cell protein 2	guanyl-nucleotide exchange factor activity	Molecular function	-
AKT1	207	v-akt murine thymoma viral oncogene homolog 1	positive regulation of glucose import	Biological process	16814735
ARSG	22901	arylsulfatase G	sulfur compound metabolic process	Biological process	18283100
OPN1MW	2652	opsin 1 (cone pigments), medium-wave-sensitive	retinoid metabolic process	Biological process	-
RGS9	8787	regulator of G-protein signaling 9	nucleus	Cellular component	-
RPS27A	6233	ribosomal protein S27a	nucleotide-binding oligomerization domain containing signaling pathway	Biological process	-
OCLN	100506658	occludin	protein domain specific binding	Molecular function	20164257
CIB1	10519	calcium and integrin binding 1 (calmyrin)	Golgi apparatus	Cellular component	-
NEU1	4758	sialidase 1 (lysosomal sialidase)	exo-alpha-(2->3)-sialidase activity	Molecular function	-
ARHGAP36	158763	Rho GTPase activating protein 36	GTPase activator activity	Molecular function	-
PPP1R26	9858	protein phosphatase 1, regulatory subunit 26	phosphatase binding	Molecular function	19389623
ABCG2	9429	ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)	protein binding	Molecular function	18056989
AAK1	22848	AP2 associated kinase 1	clathrin-coated vesicle	Cellular component	-
ARFGEF1	10565	ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)	endomembrane system organization	Biological process	20360857
PIGM	93183	phosphatidylinositol glycan anchor biosynthesis, class M	post-translational protein modification	Biological process	-
ATP6V1E2	90423	ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2	cytosol	Cellular component	-
TENM4	26011	teneurin transmembrane protein 4	neuron projection	Cellular component	-
SPATA5	166378	spermatogenesis associated 5	spermatogenesis	Biological process	-
MTMR6	9107	myotubularin related protein 6	cytosol	Cellular component	-
SLC11A1	6556	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1	late endosome	Cellular component	-
B9D1	27077	B9 protein domain 1	neuroepithelial cell differentiation	Biological process	-
TMBIM1	64114	transmembrane BAX inhibitor motif containing 1	extracellular exosome	Cellular component	19056867
PRDX1	5052	peroxiredoxin 1	response to reactive oxygen species	Biological process	-
TFDP2	7029	transcription factor Dp-2 (E2F dimerization partner 2)	transforming growth factor beta receptor signaling pathway	Biological process	-
OR51B5	282763	olfactory receptor, family 51, subfamily B, member 5	integral component of membrane	Cellular component	11121057
PSEN1	5663	presenilin 1	neuron development	Biological process	-
NUMA1	4926	nuclear mitotic apparatus protein 1	cytosol	Cellular component	-
MTDH	92140	metadherin	integral component of membrane	Cellular component	-
IL2RA	3559	interleukin 2 receptor, alpha	plasma membrane	Cellular component	-
CHKA	1119	choline kinase alpha	choline kinase activity	Molecular function	19915674
TMBIM6	7009	transmembrane BAX inhibitor motif containing 6	cytoplasm	Cellular component	9660918
NCOA6	23054	nuclear receptor coactivator 6	retinoid X receptor binding	Molecular function	11443112
KDELR1	10945	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1	COPI-coated vesicle membrane	Cellular component	-
STK11	6794	serine/threonine kinase 11	positive regulation of gluconeogenesis	Biological process	-
CYBA	1535	cytochrome b-245, alpha polypeptide	response to drug	Biological process	-
CLIC2	1193	chloride intracellular channel 2	intracellular	Cellular component	-
FOS	2353	FBJ murine osteosarcoma viral oncogene homolog	response to corticosterone	Biological process	-
ZNF16	7564	zinc finger protein 16	sequence-specific DNA binding transcription factor activity	Molecular function	-
ABCA2	20	ATP-binding cassette, sub-family A (ABC1), member 2	regulation of intracellular cholesterol transport	Biological process	15238223
NOX5	79400	NADPH oxidase, EF-hand calcium binding domain 5	superoxide-generating NADPH oxidase activity	Molecular function	11483596
PLA2G4F	255189	phospholipase A2, group IVF	phosphatidylinositol acyl-chain remodeling	Biological process	-
DCT	1638	dopachrome tautomerase	epidermis development	Biological process	8206391
PPIL6	285755	peptidylprolyl isomerase (cyclophilin)-like 6	peptidyl-prolyl cis-trans isomerase activity	Molecular function	-
PADI1	29943	peptidyl arginine deiminase, type I	protein citrullination	Biological process	-
DLG4	1742	discs, large homolog 4 (Drosophila)	basolateral plasma membrane	Cellular component	-
DVL3	1857	dishevelled segment polarity protein 3	protease binding	Molecular function	20227366
VAMP2	6844	vesicle-associated membrane protein 2 (synaptobrevin 2)	vesicle-mediated transport	Biological process	-
SNX5	27131	sorting nexin 5	ruffle	Cellular component	-
KRTAP26-1	388818	keratin associated protein 26-1	intermediate filament	Cellular component	-
PSMC4	5704	proteasome (prosome, macropain) 26S subunit, ATPase, 4	membrane	Cellular component	19946888
DHX15	1665	DEAH (Asp-Glu-Ala-His) box helicase 15	nucleus	Cellular component	-
CHPT1	56994	choline phosphotransferase 1	diacylglycerol cholinephosphotransferase activity	Molecular function	-
ABCC13	150000	ATP-binding cassette, sub-family C (CFTR/MRP), member 13, pseudogene	transmembrane transport	Biological process	-
KCNQ1	3784	potassium channel, voltage gated KQT-like subfamily Q, member 1	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization	Molecular function	12522251
TMEM229A	730130	transmembrane protein 229A	integral component of membrane	Cellular component	-
GSTZ1	2954	glutathione S-transferase zeta 1	cytosol	Cellular component	-
TMEM79	84283	transmembrane protein 79	establishment of skin barrier	Biological process	-
AGTR2	186	angiotensin II receptor, type 2	negative regulation of blood vessel endothelial cell migration	Biological process	15710780
DPH3	285381	diphthamide biosynthesis 3	cellular protein metabolic process	Biological process	-
INS	3630	insulin	protein binding	Molecular function	9388210
KLK5	25818	kallikrein-related peptidase 5	extracellular space	Cellular component	10608802
PTGDR	5729	prostaglandin D2 receptor (DP)	sleep	Biological process	-
DNAJB1	3337	DnaJ (Hsp40) homolog, subfamily B, member 1	Hsp70 protein binding	Molecular function	23921388
PARK2	5071	parkin RBR E3 ubiquitin protein ligase	kinase binding	Molecular function	17512523
EAF1	85403	ELL associated factor 1	Cajal body	Cellular component	-
EFNA2	1943	ephrin-A2	perikaryon	Cellular component	-
EREG	2069	epiregulin	neurotrophin TRK receptor signaling pathway	Biological process	-
ST3GAL2	6483	ST3 beta-galactoside alpha-2,3-sialyltransferase 2	dolichol-linked oligosaccharide biosynthetic process	Biological process	-
OGFR	11054	opioid growth factor receptor	membrane	Cellular component	-
CFAP20	29105	cilia and flagella associated protein 20	ciliary basal body	Cellular component	20118210
UBE2E1	7324	ubiquitin-conjugating enzyme E2E 1	ISG15 transferase activity	Molecular function	16428300
AGPAT9	84803	1-acylglycerol-3-phosphate O-acyltransferase 9	cellular lipid metabolic process	Biological process	-
PRAMEF15	653619	PRAME family member 15	positive regulation of cell proliferation	Biological process	-
CANX	821	calnexin	glycoprotein binding	Molecular function	-
ZIC3	7547	Zic family member 3	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	17764085
MYH7	4625	myosin, heavy chain 7, cardiac muscle, beta	actin binding	Molecular function	-
VEZF1	7716	vascular endothelial zinc finger 1	metal ion binding	Molecular function	-
TP53	7157	tumor protein p53	receptor tyrosine kinase binding	Molecular function	23027130
ATAD1	84896	ATPase family, AAA domain containing 1	negative regulation of synaptic transmission, glutamatergic	Biological process	-
OR8U1	219417	olfactory receptor, family 8, subfamily U, member 1	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
POLN	353497	polymerase (DNA directed) nu	nucleolus	Cellular component	12794064
OR56B4	196335	olfactory receptor, family 56, subfamily B, member 4	G-protein coupled receptor activity	Molecular function	-
BAP1	8314	BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)	cytoplasm	Cellular component	-
CRIM1	51232	cysteine rich transmembrane BMP regulator 1 (chordin-like)	regulation of cell growth	Biological process	-
LTBP2	4053	latent transforming growth factor beta binding protein 2	extracellular exosome	Cellular component	21362503
DNAH2	146754	dynein, axonemal, heavy chain 2	ATPase activity	Molecular function	-
TRPC4	7223	transient receptor potential cation channel, subfamily C, member 4	ion transmembrane transport	Biological process	-
HDAC4	9759	histone deacetylase 4	transcription corepressor activity	Molecular function	-
RAB2A	5862	RAB2A, member RAS oncogene family	Golgi membrane	Cellular component	-
PARD3	56288	par-3 family cell polarity regulator	asymmetric cell division	Biological process	10934474
SNW1	22938	SNW domain containing 1	nucleus	Cellular component	15878163
ACIN1	22985	apoptotic chromatin condensation inducer 1	nucleotide binding	Molecular function	-
DOCK4	9732	dedicator of cytokinesis 4	stereocilium	Cellular component	16464467
HIST1H4D	8360	histone cluster 1, H4d	negative regulation of gene expression, epigenetic	Biological process	-
DDN	23109	dendrin	nucleus	Cellular component	-
MMAA	166785	methylmalonic aciduria (cobalamin deficiency) cblA type	small molecule metabolic process	Biological process	-
PRSS50	29122	protease, serine, 50	serine-type endopeptidase activity	Molecular function	-
HSPA6	3310	heat shock 70kDa protein 6 (HSP70B')	extracellular exosome	Cellular component	19199708
TRIP12	9320	thyroid hormone receptor interactor 12	cellular response to DNA damage stimulus	Biological process	22884692
TRIM63	84676	tripartite motif containing 63, E3 ubiquitin protein ligase	microtubule	Cellular component	11243782
MIOS	54468	missing oocyte, meiosis regulator, homolog (Drosophila)	cytoplasm	Cellular component	-
IL17A	3605	interleukin 17A	cellular response to interleukin-1	Biological process	-
GJA10	84694	gap junction protein, alpha 10, 62kDa	synaptic transmission	Biological process	-
TCIRG1	10312	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3	vacuolar proton-transporting V-type ATPase complex	Cellular component	-
AGPS	8540	alkylglycerone phosphate synthase	nucleolus	Cellular component	-
S100A10	6281	S100 calcium binding protein A10	protein heterotetramerization	Biological process	23091277
LDLRAP1	26119	low density lipoprotein receptor adaptor protein 1	signaling adaptor activity	Molecular function	12221107
TAF11	6882	TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa	transcription from RNA polymerase II promoter	Biological process	-
CPXM1	56265	carboxypeptidase X (M14 family), member 1	metallocarboxypeptidase activity	Molecular function	-
TCAP	8557	titin-cap	structural constituent of muscle	Molecular function	9817758
CDC42	998	cell division cycle 42	cytoplasmic ribonucleoprotein granule	Cellular component	15121898
HELLS	3070	helicase, lymphoid-specific	nucleus	Cellular component	-
DUSP7	1849	dual specificity phosphatase 7	toll-like receptor TLR1:TLR2 signaling pathway	Biological process	-
PODXL2	50512	podocalyxin-like 2	integral component of plasma membrane	Cellular component	10722749
GPR55	9290	G protein-coupled receptor 55	bone resorption	Biological process	19805329
TCF7L2	6934	transcription factor 7-like 2 (T-cell specific, HMG-box)	cell proliferation	Biological process	12408868
ANK2	287	ankyrin 2, neuronal	positive regulation of potassium ion transport	Biological process	-
FKBP1B	2281	FK506 binding protein 1B, 12.6 kDa	cytosolic calcium ion homeostasis	Biological process	22087651
UGT2B11	10720	UDP glucuronosyltransferase 2 family, polypeptide B11	xenobiotic metabolic process	Biological process	8333863
SLC25A27	9481	solute carrier family 25, member 27	negative regulation of mitochondrial membrane potential	Biological process	-
GRK5	2869	G protein-coupled receptor kinase 5	protein autophosphorylation	Biological process	14976207
GPR141	353345	G protein-coupled receptor 141	G-protein coupled receptor activity	Molecular function	-
YAP1	10413	Yes-associated protein 1	keratinocyte differentiation	Biological process	-
ETFDH	2110	electron-transferring-flavoprotein dehydrogenase	ubiquinone binding	Molecular function	14640977
CAMK2G	818	calcium/calmodulin-dependent protein kinase II gamma	synaptic transmission	Biological process	-
EIF2AK3	9451	eukaryotic translation initiation factor 2-alpha kinase 3	negative regulation of translational initiation in response to stress	Biological process	10677345
PIGW	284098	phosphatidylinositol glycan anchor biosynthesis, class W	integral component of membrane	Cellular component	-
CBLC	23624	Cbl proto-oncogene C, E3 ubiquitin protein ligase	nucleus	Cellular component	-
APOA4	337	apolipoprotein A-IV	small molecule metabolic process	Biological process	-
BDNF	627	brain-derived neurotrophic factor	cellular response to norepinephrine stimulus	Biological process	-
CCL19	6363	chemokine (C-C motif) ligand 19	CCR chemokine receptor binding	Molecular function	20002784
TXN	7295	thioredoxin	response to radiation	Biological process	11118054
TRAF4	9618	TNF receptor-associated factor 4	bicellular tight junction	Cellular component	-
NKX2-1	7080	NK2 homeobox 1	developmental induction	Biological process	-
ACSF3	197322	acyl-CoA synthetase family member 3	ATP binding	Molecular function	-
HIST2H3A	333932	histone cluster 2, H3a	protein heterodimerization activity	Molecular function	-
NAP1L4	4676	nucleosome assembly protein 1-like 4	cytoplasm	Cellular component	9325046
ACVR2A	92	activin A receptor, type IIA	regulation of nitric-oxide synthase activity	Biological process	-
ADAM10	102	ADAM metallopeptidase domain 10	zinc ion binding	Molecular function	-
KCNA5	3741	potassium channel, voltage gated shaker related subfamily A, member 5	Golgi apparatus	Cellular component	16780588
VPS4A	27183	vacuolar protein sorting 4 homolog A (S. cerevisiae)	midbody	Cellular component	17853893
RBPMS	11030	RNA binding protein with multiple splicing	nucleoplasm	Cellular component	-
SRY	6736	sex determining region Y	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
KIF1B	23095	kinesin family member 1B	kinesin binding	Molecular function	10341097
NOG	9241	noggin	BMP signaling pathway	Biological process	-
SYDE2	84144	synapse defective 1, Rho GTPase, homolog 2 (C. elegans)	cytosol	Cellular component	-
TSHZ3	57616	teashirt zinc finger homeobox 3	in utero embryonic development	Biological process	-
PEX11A	8800	peroxisomal biogenesis factor 11 alpha	peroxisome organization	Biological process	9792670
USP17L22	100287513	ubiquitin specific peptidase 17-like family member 22	protein deubiquitination	Biological process	-
GLI3	2737	GLI family zinc finger 3	smoothened signaling pathway	Biological process	11001584
COL1A2	1278	collagen, type I, alpha 2	blood vessel development	Biological process	17211858
LY6K	54742	lymphocyte antigen 6 complex, locus K	extracellular region	Cellular component	-
HAUS6	54801	HAUS augmin-like complex, subunit 6	centrosome	Cellular component	21399614
CD83	9308	CD83 molecule	signal transduction	Biological process	9310491
PRKAR2B	5577	protein kinase, cAMP-dependent, regulatory, type II, beta	signal transduction	Biological process	-
PAX6	5080	paired box 6	central nervous system development	Biological process	10747901
HMGA1	3159	high mobility group AT-hook 1	protein binding	Molecular function	10428834
PI4KB	5298	phosphatidylinositol 4-kinase, catalytic, beta	phosphatidylinositol biosynthetic process	Biological process	-
ZNF740	283337	zinc finger protein 740	metal ion binding	Molecular function	-
RAB7B	338382	RAB7B, member RAS oncogene family	GTP binding	Molecular function	-
CALM3	808	calmodulin 3 (phosphorylase kinase, delta)	regulation of cardiac muscle contraction	Biological process	23040497
CATSPER2	117155	cation channel, sperm associated 2	single fertilization	Biological process	-
FAM166A	401565	family with sequence similarity 166, member A	nucleus	Cellular component	21630459
KCNN3	3782	potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3	small conductance calcium-activated potassium channel activity	Molecular function	-
ABR	29	active BCR-related	actin cytoskeleton organization	Biological process	-
AP5B1	91056	adaptor-related protein complex 5, beta 1 subunit	AP-type membrane coat adaptor complex	Cellular component	22022230
HAUS6	54801	HAUS augmin-like complex, subunit 6	mitotic nuclear division	Biological process	-
AXIN1	8312	axin 1	nucleocytoplasmic transport	Biological process	-
SLC25A5	292	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5	ubiquitin protein ligase binding	Molecular function	19725078
WIBG	84305	within bgcn homolog (Drosophila)	cytoplasm	Cellular component	-
FCER1A	2205	Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide	serotonin secretion	Biological process	-
HIST1H2BI	8346	histone cluster 1, H2bi	defense response to Gram-positive bacterium	Biological process	12860195
PDZK1	5174	PDZ domain containing 1	regulation of anion transport	Biological process	-
IFITM3	10410	interferon induced transmembrane protein 3	negative regulation of viral entry into host cell	Biological process	23358889
HMHA1	23526	histocompatibility (minor) HA-1	metal ion binding	Molecular function	-
PARK7	11315	parkinson protein 7	plasma membrane	Cellular component	-
KIFAP3	22920	kinesin-associated protein 3	endoplasmic reticulum	Cellular component	-
SH3BP4	23677	SH3-domain binding protein 4	negative regulation of cell proliferation	Biological process	22575674
TPR	7175	translocated promoter region, nuclear basket protein	positive regulation of protein export from nucleus	Biological process	-
FOXE3	2301	forkhead box E3	sequence-specific DNA binding transcription factor activity	Molecular function	8825632
KLRC2	3822	killer cell lectin-like receptor subfamily C, member 2	cellular defense response	Biological process	9683661
KIF14	9928	kinesin family member 14	ATPase activity	Molecular function	-
RER1	11079	retention in endoplasmic reticulum sorting receptor 1	Golgi apparatus	Cellular component	-
NR2F6	2063	nuclear receptor subfamily 2, group F, member 6	zinc ion binding	Molecular function	-
PSMD9	5715	proteasome (prosome, macropain) 26S subunit, non-ATPase, 9	viral process	Biological process	-
OPCML	4978	opioid binding protein/cell adhesion molecule-like	extracellular exosome	Cellular component	23376485
VAMP2	6844	vesicle-associated membrane protein 2 (synaptobrevin 2)	protein complex assembly	Biological process	-
SHPRH	257218	SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase	nucleosome assembly	Biological process	-
NPC1	4864	Niemann-Pick disease, type C1	protein glycosylation	Biological process	10821832
APCDD1	147495	adenomatosis polyposis coli down-regulated 1	hair follicle development	Biological process	20393562
LOXL2	4017	lysyl oxidase-like 2	negative regulation of transcription, DNA-templated	Biological process	16096638
TPH2	121278	tryptophan hydroxylase 2	neuron projection	Cellular component	-
TAGLN3	29114	transgelin 3	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
GCH1	2643	GTP cyclohydrolase 1	GTP cyclohydrolase I activity	Molecular function	11284739
CBX7	23492	chromobox homolog 7	methylated histone binding	Molecular function	-
NPFFR2	10886	neuropeptide FF receptor 2	plasma membrane	Cellular component	-
TAL2	6887	T-cell acute lymphocytic leukemia 2	thalamus development	Biological process	-
AIFM3	150209	apoptosis-inducing factor, mitochondrion-associated, 3	oxidoreductase activity	Molecular function	-
NOD2	64127	nucleotide-binding oligomerization domain containing 2	maintenance of gastrointestinal epithelium	Biological process	17058067
DAB2	1601	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)	negative regulation of apoptotic process	Biological process	15734730
NHLH1	4807	nescient helix loop helix 1	transcription, DNA-templated	Biological process	-
DDO	8528	D-aspartate oxidase	oxidation-reduction process	Biological process	-
ZNF449	203523	zinc finger protein 449	nucleus	Cellular component	-
PRSS8	5652	protease, serine, 8	proteolysis	Biological process	-
TBX20	57057	T-box 20	negative regulation of transcription, DNA-templated	Biological process	-
SDC3	9672	syndecan 3	extracellular matrix organization	Biological process	-
TPM3	7170	tropomyosin 3	actin binding	Molecular function	-
FBLN2	2199	fibulin 2	extracellular vesicle	Cellular component	24769233
PLK2	10769	polo-like kinase 2	long-term synaptic potentiation	Biological process	-
ERP29	10961	endoplasmic reticulum protein 29	negative regulation of gene expression	Biological process	22064321
UCK1	83549	uridine-cytidine kinase 1	CTP salvage	Biological process	-
SH3RF1	57630	SH3 domain containing ring finger 1	negative regulation of apoptotic process	Biological process	21586138
ZNF20	7568	zinc finger protein 20	transcription, DNA-templated	Biological process	-
ANGPT2	285	angiopoietin 2	maternal process involved in female pregnancy	Biological process	-
AK7	122481	adenylate kinase 7	adenylate kinase activity	Molecular function	21080915
CSK	1445	c-src tyrosine kinase	adherens junction organization	Biological process	-
LRP5	4041	low density lipoprotein receptor-related protein 5	regulation of bone remodeling	Biological process	-
LILRB2	10288	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	cytoplasm	Cellular component	19124746
GIMAP6	474344	GTPase, IMAP family member 6	cytosol	Cellular component	23454188
PDGFRA	5156	platelet-derived growth factor receptor, alpha polypeptide	protein autophosphorylation	Biological process	1646396
RABL3	285282	RAB, member of RAS oncogene family-like 3	GTP binding	Molecular function	-
ATXN2L	11273	ataxin 2-like	stress granule assembly	Biological process	23209657
TCF19	6941	transcription factor 19	transcription, DNA-templated	Biological process	-
UGT3A2	167127	UDP glycosyltransferase 3 family, polypeptide A2	glucuronosyltransferase activity	Molecular function	-
SDHD	6392	succinate dehydrogenase complex, subunit D, integral membrane protein	tricarboxylic acid cycle	Biological process	-
ACTR3	10096	ARP3 actin-related protein 3 homolog (yeast)	response to antibiotic	Biological process	-
CNTN2	6900	contactin 2 (axonal)	identical protein binding	Molecular function	12963709
NQO1	1728	NAD(P)H dehydrogenase, quinone 1	extracellular exosome	Cellular component	23376485
GAREM	64762	GRB2 associated, regulator of MAPK1	positive regulation of cell division	Biological process	-
FKBP5	2289	FK506 binding protein 5	membrane	Cellular component	19946888
LGMN	5641	legumain	renal system process	Biological process	-
NCOR1	9611	nuclear receptor corepressor 1	protein binding	Molecular function	10049357
ARL14	80117	ADP-ribosylation factor-like 14	cytoplasmic membrane-bounded vesicle	Cellular component	-
TWIST1	7291	twist family bHLH transcription factor 1	negative regulation of apoptotic process	Biological process	-
RPH3A	22895	rabphilin 3A	clathrin binding	Molecular function	-
KIF22	3835	kinesin family member 22	antigen processing and presentation of exogenous peptide antigen via MHC class II	Biological process	-
PPP3CA	5530	protein phosphatase 3, catalytic subunit, alpha isozyme	Z disc	Cellular component	-
ALAS1	211	5'-aminolevulinate synthase 1	5-aminolevulinate synthase activity	Molecular function	-
UBR2	23304	ubiquitin protein ligase E3 component n-recognin 2	chromatin	Cellular component	-
CYTH2	9266	cytohesin 2	endocytosis	Biological process	9417041
DDX5	1655	DEAD (Asp-Glu-Ala-Asp) box helicase 5	regulation of osteoblast differentiation	Biological process	-
SLX4	84464	SLX4 structure-specific endonuclease subunit	5'-flap endonuclease activity	Molecular function	19595721
GRM2	2912	glutamate receptor, metabotropic 2	regulation of synaptic transmission, glutamatergic	Biological process	-
LDLRAD4	753	low density lipoprotein receptor class A domain containing 4	negative regulation of SMAD protein complex assembly	Biological process	24627487
PLA2G6	8398	phospholipase A2, group VI (cytosolic, calcium-independent)	urinary bladder smooth muscle contraction	Biological process	-
HIPK1	204851	homeodomain interacting protein kinase 1	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	Biological process	-
HIST1H2AI	8329	histone cluster 1, H2ai	protein heterodimerization activity	Molecular function	-
KIF5B	3799	kinesin family member 5B	kinesin complex	Cellular component	-
TNNT3	7140	troponin T type 3 (skeletal, fast)	metabolic process	Biological process	8987992
USP28	57646	ubiquitin specific peptidase 28	cellular response to DNA damage stimulus	Biological process	17873522
GABARAPL2	11345	GABA(A) receptor-associated protein-like 2	beta-tubulin binding	Molecular function	-
FNBP1L	54874	formin binding protein 1-like	cytoskeleton	Cellular component	-
ARNTL	406	aryl hydrocarbon receptor nuclear translocator-like	nucleus	Cellular component	24005054
SASH1	23328	SAM and SH3 domain containing 1	positive regulation of NIK/NF-kappaB signaling	Biological process	23776175
ABCA8	10351	ATP-binding cassette, sub-family A (ABC1), member 8	intracellular membrane-bounded organelle	Cellular component	-
SDC1	6382	syndecan 1	cytoplasm	Cellular component	-
ARHGEF25	115557	Rho guanine nucleotide exchange factor (GEF) 25	plasma membrane	Cellular component	-
MLC1	23209	megalencephalic leukoencephalopathy with subcortical cysts 1	basolateral plasma membrane	Cellular component	18165104
FGR	2268	FGR proto-oncogene, Src family tyrosine kinase	immunoglobulin receptor binding	Molecular function	-
C7orf49	78996	chromosome 7 open reading frame 49	protein binding	Molecular function	25416956
KITLG	4254	KIT ligand	positive regulation of MAP kinase activity	Biological process	-
BAD	572	BCL2-associated agonist of cell death	positive regulation of type B pancreatic cell development	Biological process	-
MICALCL	84953	MICAL C-terminal like	mitogen-activated protein kinase binding	Molecular function	-
GCHFR	2644	GTP cyclohydrolase I feedback regulator	dendrite	Cellular component	16778797
ICAM1	3383	intercellular adhesion molecule 1	receptor activity	Molecular function	2538243
EBF1	1879	early B-cell factor 1	sequence-specific DNA binding transcription factor activity	Molecular function	-
PITPNM1	9600	phosphatidylinositol transfer protein, membrane-associated 1	phototransduction	Biological process	9680295
SERPINA4	5267	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4	extracellular space	Cellular component	20551380
OR5V1	81696	olfactory receptor, family 5, subfamily V, member 1	G-protein coupled receptor activity	Molecular function	-
FGF7	2252	fibroblast growth factor 7	growth factor activity	Molecular function	-
HIVEP3	59269	human immunodeficiency virus type I enhancer binding protein 3	positive regulation of transcription, DNA-templated	Biological process	15790681
RPF1	80135	ribosome production factor 1 homolog (S. cerevisiae)	protein binding	Molecular function	25416956
B4GALT7	11285	xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7	glycosaminoglycan biosynthetic process	Biological process	10438455
GDNF	2668	glial cell derived neurotrophic factor	positive regulation of ureteric bud formation	Biological process	8657307
TSEN2	80746	TSEN2 tRNA splicing endonuclease subunit	nucleolus	Cellular component	-
DAB2	1601	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)	negative regulation of extrinsic apoptotic signaling pathway	Biological process	-
NRK	203447	Nik related kinase	MAPK cascade	Biological process	-
SLCO1A2	6579	solute carrier organic anion transporter family, member 1A2	organic anion transport	Biological process	9007731
LIN7A	8825	lin-7 homolog A (C. elegans)	synaptic transmission	Biological process	-
SMNDC1	10285	survival motor neuron domain containing 1	spliceosomal complex assembly	Biological process	-
NCL	4691	nucleolin	positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter	Biological process	24071584
KCNA1	3736	potassium channel, voltage gated shaker related subfamily A, member 1	regulation of ion transmembrane transport	Biological process	-
FBLIM1	54751	filamin binding LIM protein 1	protein binding	Molecular function	25416956
RFX3	5991	regulatory factor X, 3 (influences HLA class II expression)	cell maturation	Biological process	20413507
T	6862	T, brachyury homolog (mouse)	mesoderm development	Biological process	8963900
ACER1	125981	alkaline ceramidase 1	response to alkaline pH	Biological process	17713573
DRG1	4733	developmentally regulated GTP binding protein 1	protein binding	Molecular function	16189514
USP17L13	100287238	ubiquitin specific peptidase 17-like family member 13	endoplasmic reticulum	Cellular component	-
JAG2	3714	jagged 2	epithelial cell apoptotic process involved in palatal shelf morphogenesis	Biological process	-
NFYA	4800	nuclear transcription factor Y, alpha	transcription cofactor binding	Molecular function	-
H3F3B	3021	H3 histone, family 3B (H3.3B)	RNA polymerase II distal enhancer sequence-specific DNA binding	Molecular function	19633671
RHBDF1	64285	rhomboid 5 homolog 1 (Drosophila)	endoplasmic reticulum membrane	Cellular component	18832597
HIST1H3G	8355	histone cluster 1, H3g	regulation of gene silencing	Biological process	16267050
PPIAL4A	653505	peptidylprolyl isomerase A (cyclophilin A)-like 4A	cytoplasm	Cellular component	-
IL12B	3593	interleukin 12B	interleukin-12 receptor binding	Molecular function	9603733
BHMT2	23743	betaine--homocysteine S-methyltransferase 2	amino-acid betaine metabolic process	Biological process	18230605
AGRP	181	agouti related neuropeptide	neuronal cell body	Cellular component	-
TRAPPC8	22878	trafficking protein particle complex 8	peroxisome degradation	Biological process	-
ZNF207	7756	zinc finger protein 207	condensed chromosome kinetochore	Cellular component	-
RUNX2	860	runt-related transcription factor 2	transcription factor complex	Cellular component	-
MID1IP1	58526	MID1 interacting protein 1	negative regulation of microtubule depolymerization	Biological process	-
MALL	7851	mal, T-cell differentiation protein-like	integral component of membrane	Cellular component	-
BRAF	673	B-Raf proto-oncogene, serine/threonine kinase	small GTPase mediated signal transduction	Biological process	-
OPRD1	4985	opioid receptor, delta 1	regulation of sensory perception of pain	Biological process	-
POU6F1	5463	POU class 6 homeobox 1	sequence-specific DNA binding transcription factor activity	Molecular function	-
ELOVL5	60481	ELOVL fatty acid elongase 5	dendritic tree	Cellular component	25065913
DMRT3	58524	doublesex and mab-3 related transcription factor 3	adult walking behavior	Biological process	-
ZNF358	140467	zinc finger protein 358	nucleus	Cellular component	-
KEAP1	9817	kelch-like ECH-associated protein 1	transcription factor binding	Molecular function	17015834
AREG	374	amphiregulin	epidermal growth factor receptor binding	Molecular function	-
CDKN1A	1026	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	response to X-ray	Biological process	-
INHA	3623	inhibin, alpha	response to external stimulus	Biological process	10320815
OR2A12	346525	olfactory receptor, family 2, subfamily A, member 12	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
IL9R	3581	interleukin 9 receptor	interleukin-9-mediated signaling pathway	Biological process	-
PDHA2	5161	pyruvate dehydrogenase (lipoamide) alpha 2	tricarboxylic acid cycle	Biological process	-
EYA2	2139	EYA transcriptional coactivator and phosphatase 2	DNA repair	Biological process	-
CTSG	1511	cathepsin G	protein phosphorylation	Biological process	8573071
BTG2	7832	BTG family, member 2	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
CASP8	841	caspase 8, apoptosis-related cysteine peptidase	cellular response to organic cyclic compound	Biological process	-
CXCR6	10663	chemokine (C-X-C motif) receptor 6	chemokine-mediated signaling pathway	Biological process	-
BECN1	8678	beclin 1, autophagy related	phosphatidylinositol 3-kinase complex, class III, type I	Cellular component	-
CUL5	8065	cullin 5	cell proliferation	Biological process	9037604
YBX1	4904	Y box binding protein 1	nuclear membrane	Cellular component	-
ETFA	2108	electron-transfer-flavoprotein, alpha polypeptide	electron carrier activity	Molecular function	10423253
KRT19	3880	keratin 19, type I	protein binding	Molecular function	15846844
PRPF38A	84950	pre-mRNA processing factor 38A	RNA splicing	Biological process	-
ZBTB38	253461	zinc finger and BTB domain containing 38	protein homodimerization activity	Molecular function	16354688
PKD2L1	9033	polycystic kidney disease 2-like 1	cation transmembrane transporter activity	Molecular function	-
NPPA	4878	natriuretic peptide A	cardiac muscle hypertrophy in response to stress	Biological process	-
PDE3A	5139	phosphodiesterase 3A, cGMP-inhibited	negative regulation of vascular permeability	Biological process	17704206
TSNAXIP1	55815	translin-associated factor X interacting protein 1	cellular_component	Cellular component	-
ZNF277	11179	zinc finger protein 277	transcription, DNA-templated	Biological process	-
RILPL1	353116	Rab interacting lysosomal protein-like 1	primary cilium	Cellular component	-
CDC25C	995	cell division cycle 25C	protein kinase binding	Molecular function	14968113
ZBTB2	57621	zinc finger and BTB domain containing 2	DNA binding	Molecular function	-
LIF	3976	leukemia inhibitory factor	cytokine activity	Molecular function	7957045
BSPRY	54836	B-box and SPRY domain containing	perinuclear region of cytoplasm	Cellular component	-
CIR1	9541	corepressor interacting with RBPJ, 1	regulation of transcription from RNA polymerase II promoter	Biological process	18663143
CCDC107	203260	coiled-coil domain containing 107	integral component of membrane	Cellular component	-
CDAN1	146059	codanin 1	cytoplasm	Cellular component	-
POSTN	10631	periostin, osteoblast specific factor	regulation of Notch signaling pathway	Biological process	-
SESN3	143686	sestrin 3	response to insulin	Biological process	-
ZNF445	353274	zinc finger protein 445	sequence-specific DNA binding transcription factor activity	Molecular function	-
GRPEL2	134266	GrpE-like 2, mitochondrial (E. coli)	mitochondrial inner membrane	Cellular component	-
HTT	3064	huntingtin	cell aging	Biological process	-
AGPAT6	137964	1-acylglycerol-3-phosphate O-acyltransferase 6	diacylglycerol metabolic process	Biological process	-
IFT57	55081	intraflagellar transport 57	photoreceptor connecting cilium	Cellular component	-
TOM1L2	146691	target of myb1-like 2 (chicken)	protein binding	Molecular function	16412388
NFKB1	4790	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	negative regulation of transcription from RNA polymerase II promoter	Biological process	19881551
KCNK13	56659	potassium channel, two pore domain subfamily K, member 13	plasma membrane	Cellular component	-
PPP1CA	5499	protein phosphatase 1, catalytic subunit, alpha isozyme	entrainment of circadian clock by photoperiod	Biological process	-
FABP4	2167	fatty acid binding protein 4, adipocyte	nucleus	Cellular component	-
SLC26A1	10861	solute carrier family 26 (anion exchanger), member 1	chloride transmembrane transport	Biological process	-
SRFBP1	153443	serum response factor binding protein 1	transcription, DNA-templated	Biological process	-
RAPGEF4	11069	Rap guanine nucleotide exchange factor (GEF) 4	small GTPase mediated signal transduction	Biological process	-
RHOU	58480	ras homolog family member U	Golgi membrane	Cellular component	-
NUP98	4928	nucleoporin 98kDa	cellular protein metabolic process	Biological process	-
SNCA	6622	synuclein, alpha (non A4 component of amyloid precursor)	rough endoplasmic reticulum	Cellular component	-
CDCA8	55143	cell division cycle associated 8	chromosome passenger complex	Cellular component	15260989
FXYD6	53826	FXYD domain containing ion transport regulator 6	transmembrane transport	Biological process	-
KLF12	11278	Kruppel-like factor 12	transcription, DNA-templated	Biological process	-
TSTA3	7264	tissue specific transplantation antigen P35B	cytoplasm	Cellular component	11698403
RAMP3	10268	receptor (G protein-coupled) activity modifying protein 3	receptor activity	Molecular function	10882736
SYT1	6857	synaptotagmin I	synaptic transmission	Biological process	-
RNF168	165918	ring finger protein 168, E3 ubiquitin protein ligase	cellular response to DNA damage stimulus	Biological process	19500350
ALDOC	230	aldolase C, fructose-bisphosphate	extracellular exosome	Cellular component	19056867
FKBP11	51303	FK506 binding protein 11, 19 kDa	membrane	Cellular component	19946888
PAFAH1B1	5048	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	protein homodimerization activity	Molecular function	-
TMCC3	57458	transmembrane and coiled-coil domain family 3	integral component of membrane	Cellular component	-
HSCB	150274	HscB mitochondrial iron-sulfur cluster co-chaperone	mitochondrion	Cellular component	12938016
BAD	572	BCL2-associated agonist of cell death	response to glucocorticoid	Biological process	-
ACVR1C	130399	activin A receptor, type IC	nodal signaling pathway	Biological process	15150278
CYP26A1	1592	cytochrome P450, family 26, subfamily A, polypeptide 1	small molecule metabolic process	Biological process	-
PSMA1	5682	proteasome (prosome, macropain) subunit, alpha type, 1	cytosol	Cellular component	-
PSEN2	5664	presenilin 2	lung alveolus development	Biological process	-
PLCB2	5330	phospholipase C, beta 2	phospholipid metabolic process	Biological process	1644792
NPTN	27020	neuroplastin	peptidyl-tyrosine phosphorylation	Biological process	-
JCHAIN	3512	joining chain of multimeric IgA and IgM	antibacterial humoral response	Biological process	23250751
PSME4	23198	proteasome (prosome, macropain) activator subunit 4	innate immune response	Biological process	-
AKAP10	11216	A kinase (PRKA) anchor protein 10	cytosol	Cellular component	-
NAA38	84316	N(alpha)-acetyltransferase 38, NatC auxiliary subunit	polysome	Cellular component	19398576
SCNN1D	6339	sodium channel, non voltage gated 1 delta subunit	actin cytoskeleton	Cellular component	-
ATP2B2	491	ATPase, Ca++ transporting, plasma membrane 2	cGMP metabolic process	Biological process	-
ESR1	2099	estrogen receptor 1	protein binding	Molecular function	10359819
HTR4	3360	5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled	membrane	Cellular component	16102731
WDR82	80335	WD repeat domain 82	histone methyltransferase activity (H3-K4 specific)	Molecular function	17355966
CLVS1	157807	clavesin 1	lysosome organization	Biological process	-
GABBR1	2550	gamma-aminobutyric acid (GABA) B receptor, 1	postsynaptic membrane	Cellular component	-
EIF5A2	56648	eukaryotic translation initiation factor 5A2	translational frameshifting	Biological process	-
CRYBA1	1411	crystallin, beta A1	structural constituent of eye lens	Molecular function	-
ACAD8	27034	acyl-CoA dehydrogenase family, member 8	valine catabolic process	Biological process	-
REEP1	65055	receptor accessory protein 1	olfactory receptor binding	Molecular function	15550249
SLK	9748	STE20-like kinase	signal transduction by protein phosphorylation	Biological process	-
FEV	54738	FEV (ETS oncogene family)	neuron fate specification	Biological process	-
RSPO2	340419	R-spondin 2	trachea cartilage morphogenesis	Biological process	-
PLIN2	123	perilipin 2	lipid particle	Cellular component	14741744
ZNF346	23567	zinc finger protein 346	double-stranded RNA binding	Molecular function	10488071
MET	4233	MET proto-oncogene, receptor tyrosine kinase	brain development	Biological process	-
TNPO1	3842	transportin 1	organelle organization	Biological process	-
KAT8	84148	K(lysine) acetyltransferase 8	regulation of autophagy	Biological process	23863932
CDK8	1024	cyclin-dependent kinase 8	RNA polymerase II carboxy-terminal domain kinase activity	Molecular function	-
MT1G	4495	metallothionein 1G	cellular response to copper ion	Biological process	3403543
PABPC1	26986	poly(A) binding protein, cytoplasmic 1	nuclear-transcribed mRNA poly(A) tail shortening	Biological process	-
POLR1C	9533	polymerase (RNA) I polypeptide C, 30kDa	regulation of gene expression, epigenetic	Biological process	-
ATP5F1	515	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1	mitochondrial proton-transporting ATP synthase complex	Cellular component	12110673
STX5	6811	syntaxin 5	retrograde transport, endosome to Golgi	Biological process	15215310
AQP1	358	aquaporin 1 (Colton blood group)	cellular hyperosmotic response	Biological process	11922632
UBE2L3	7332	ubiquitin-conjugating enzyme E2L 3	nucleus	Cellular component	-
ELP3	55140	elongator acetyltransferase complex subunit 3	histone H3 acetylation	Biological process	11714725
SIX1	6495	SIX homeobox 1	nucleolus	Cellular component	-
ZNF473	25888	zinc finger protein 473	nucleoplasm	Cellular component	-
RPL30	6156	ribosomal protein L30	viral transcription	Biological process	-
TSC2	7249	tuberous sclerosis 2	TSC1-TSC2 complex	Cellular component	9580671
UNC13B	10497	unc-13 homolog B (C. elegans)	synaptic vesicle docking	Biological process	-
GALNT15	117248	polypeptide N-acetylgalactosaminyltransferase 15	O-glycan processing	Biological process	-
REL	5966	v-rel avian reticuloendotheliosis viral oncogene homolog	sequence-specific DNA binding transcription factor activity	Molecular function	8423996
DAG1	1605	dystroglycan 1 (dystrophin-associated glycoprotein 1)	plasma membrane	Cellular component	-
FURIN	5045	furin (paired basic amino acid cleaving enzyme)	secretion by cell	Biological process	8615794
CPEB1	64506	cytoplasmic polyadenylation element binding protein 1	postsynaptic density	Cellular component	-
CLEC4E	26253	C-type lectin domain family 4, member E	positive regulation of cytokine secretion	Biological process	-
TRAPPC8	22878	trafficking protein particle complex 8	ER to Golgi vesicle-mediated transport	Biological process	-
DLG1	1739	discs, large homolog 1 (Drosophila)	extracellular exosome	Cellular component	20458337
P2RY12	64805	purinergic receptor P2Y, G-protein coupled, 12	plasma membrane	Cellular component	-
E2F7	144455	E2F transcription factor 7	DNA damage response, signal transduction by p53 class mediator	Biological process	22802528
CDC23	8697	cell division cycle 23	protein K11-linked ubiquitination	Biological process	18485873
C1R	715	complement component 1, r subcomponent	serine-type endopeptidase activity	Molecular function	-
HK2	3099	hexokinase 2	response to ischemia	Biological process	-
CHST10	9486	carbohydrate sulfotransferase 10	sulfotransferase activity	Molecular function	9478973
DVL1	1855	dishevelled segment polarity protein 1	skeletal muscle acetylcholine-gated channel clustering	Biological process	-
SKIL	6498	SKI-like proto-oncogene	cytoplasm	Cellular component	16109768
IFT20	90410	intraflagellar transport 20	centriole	Cellular component	-
BZRAP1	9256	benzodiazepine receptor (peripheral) associated protein 1	biological_process	Biological process	-
SOX2	6657	SRY (sex determining region Y)-box 2	positive regulation of cell-cell adhesion	Biological process	-
COPS5	10987	COP9 signalosome subunit 5	positive regulation of transcription from RNA polymerase II promoter	Biological process	16410250
IGFBP3	3486	insulin-like growth factor binding protein 3	protein binding	Molecular function	14561895
TMEM110	375346	transmembrane protein 110	biological_process	Biological process	-
HDAC4	9759	histone deacetylase 4	activating transcription factor binding	Molecular function	10983972
IL27RA	9466	interleukin 27 receptor, alpha	negative regulation of type 2 immune response	Biological process	-
RAPH1	65059	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1	cell-matrix adhesion	Biological process	-
USP9Y	8287	ubiquitin specific peptidase 9, Y-linked	cell migration	Biological process	-
GUCY2D	3000	guanylate cyclase 2D, membrane (retina-specific)	phototransduction, visible light	Biological process	-
FAU	2197	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed	translation	Biological process	-
ANXA3	306	annexin A3	positive regulation of angiogenesis	Biological process	16236264
TDRD12	91646	tudor domain containing 12	positive regulation of protein targeting to mitochondrion	Biological process	24270810
APOA1	335	apolipoprotein A-I	blood coagulation	Biological process	-
CHM	1121	choroideremia (Rab escort protein 1)	protein targeting to membrane	Biological process	7957092
NTRK2	4915	neurotrophic tyrosine kinase, receptor, type 2	vasculogenesis	Biological process	-
ICAM2	3384	intercellular adhesion molecule 2	plasma membrane	Cellular component	-
HDC	3067	histidine decarboxylase	histidine metabolic process	Biological process	1487235
CACNA1B	774	calcium channel, voltage-dependent, N type, alpha 1B subunit	protein binding	Molecular function	11438518
MYL9	10398	myosin, light chain 9, regulatory	ephrin receptor signaling pathway	Biological process	-
SLC6A17	388662	solute carrier family 6 (neutral amino acid transporter), member 17	integral component of plasma membrane	Cellular component	-
EPCAM	4072	epithelial cell adhesion molecule	protein binding	Molecular function	16054130
TXNDC2	84203	thioredoxin domain containing 2 (spermatozoa)	sulfate assimilation	Biological process	-
RTN2	6253	reticulon 2	regulation of glucose import	Biological process	-
TRIM38	10475	tripartite motif containing 38	ligase activity	Molecular function	-
PSMC5	5705	proteasome (prosome, macropain) 26S subunit, ATPase, 5	TBP-class protein binding	Molecular function	-
DNAAF1	123872	dynein, axonemal, assembly factor 1	inner dynein arm assembly	Biological process	19944400
NOTCH1	4851	notch 1	spermatogenesis	Biological process	-
STK17B	9262	serine/threonine kinase 17b	endoplasmic reticulum-Golgi intermediate compartment	Cellular component	-
ADRA1B	147	adrenoceptor alpha 1B	positive regulation of the force of heart contraction by epinephrine-norepinephrine	Biological process	-
FUT10	84750	fucosyltransferase 10 (alpha (1,3) fucosyltransferase)	protein folding	Biological process	11698403
TMEM43	79188	transmembrane protein 43	protein self-association	Molecular function	-
APBA1	320	amyloid beta (A4) precursor protein-binding, family A, member 1	in utero embryonic development	Biological process	-
TAGLN	6876	transgelin	actin filament binding	Molecular function	-
APLF	200558	aprataxin and PNKP like factor	cytosol	Cellular component	-
TGFB1	7040	transforming growth factor, beta 1	aging	Biological process	-
FAM89B	23625	family with sequence similarity 89, member B	transcription corepressor binding	Molecular function	-
RACGAP1	29127	Rac GTPase activating protein 1	regulation of attachment of spindle microtubules to kinetochore	Biological process	15642749
ATP8B3	148229	ATPase, aminophospholipid transporter, class I, type 8B, member 3	binding of sperm to zona pellucida	Biological process	-
APOA1BP	128240	apolipoprotein A-I binding protein	extracellular exosome	Cellular component	23376485
ABCD1	215	ATP-binding cassette, sub-family D (ALD), member 1	identical protein binding	Molecular function	10551832
PRKD2	25865	protein kinase D2	Golgi apparatus	Cellular component	-
NDUFA3	4696	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa	mitochondrial inner membrane	Cellular component	-
HSPA5	3309	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	plasma membrane	Cellular component	-
HPSE	10855	heparanase	heparan sulfate proteoglycan catabolic process	Biological process	12213822
JUN	3725	jun proto-oncogene	response to cAMP	Biological process	-
ARMCX5	64860	armadillo repeat containing, X-linked 5	protein binding	Molecular function	25416956
GCKR	2646	glucokinase (hexokinase 4) regulator	protein domain specific binding	Molecular function	-
ARL2	402	ADP-ribosylation factor-like 2	mitochondrial matrix	Cellular component	-
WNK1	65125	WNK lysine deficient protein kinase 1	ion transport	Biological process	-
GDF10	2662	growth differentiation factor 10	SMAD protein signal transduction	Biological process	-
PPIG	9360	peptidylprolyl isomerase G (cyclophilin G)	peptidyl-prolyl cis-trans isomerase activity	Molecular function	-
EPHA4	2043	EPH receptor A4	axon	Cellular component	-
GPX1	2876	glutathione peroxidase 1	vasodilation	Biological process	-
OR10J3	441911	olfactory receptor, family 10, subfamily J, member 3	detection of chemical stimulus involved in sensory perception	Biological process	-
MPP1	4354	membrane protein, palmitoylated 1, 55kDa	nucleotide phosphorylation	Biological process	1310897
RB1	5925	retinoblastoma 1	androgen receptor signaling pathway	Biological process	15572661
MCM7	4176	minichromosome maintenance complex component 7	cytoplasm	Cellular component	-
HMP19	51617	HMP19 protein	integral component of membrane	Cellular component	-
TAF6L	10629	TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa	regulation of transcription from RNA polymerase II promoter	Biological process	9674425
KCNK1	3775	potassium channel, two pore domain subfamily K, member 1	potassium ion transmembrane transport	Biological process	22282804
MVB12B	89853	multivesicular body subunit 12B	lipid binding	Molecular function	22232651
MOK	5891	MOK protein kinase	signal transduction	Biological process	10421840
HSPA1A	3303	heat shock 70kDa protein 1A	ATPase activity	Molecular function	23921388
RHOJ	57381	ras homolog family member J	extracellular exosome	Cellular component	23533145
PODXL	5420	podocalyxin-like	slit diaphragm	Cellular component	-
SMAD4	4089	SMAD family member 4	palate development	Biological process	-
TGFBR2	7048	transforming growth factor, beta receptor II (70/80kDa)	metal ion binding	Molecular function	-
OR5T2	219464	olfactory receptor, family 5, subfamily T, member 2	G-protein coupled receptor signaling pathway	Biological process	-
HTR1D	3352	5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled	synaptic transmission	Biological process	-
KIF14	9928	kinesin family member 14	microtubule-based movement	Biological process	-
RBM11	54033	RNA binding motif protein 11	protein binding	Molecular function	25416956
BBS2	583	Bardet-Biedl syndrome 2	cilium assembly	Biological process	-
CELSR2	1952	cadherin, EGF LAG seven-pass G-type receptor 2	regulation of protein localization	Biological process	-
DEFB121	245934	defensin, beta 121	defense response to bacterium	Biological process	-
TRAF2	7186	TNF receptor-associated factor 2	thioesterase binding	Molecular function	11279055
IL1B	3553	interleukin 1, beta	positive regulation of mitotic nuclear division	Biological process	2989698
AGRN	375790	agrin	dystroglycan binding	Molecular function	-
GABPA	2551	GA binding protein transcription factor, alpha subunit 60kDa	positive regulation of transcription from RNA polymerase II promoter	Biological process	12750007
TRAT1	50852	T cell receptor associated transmembrane adaptor 1	signal transduction	Biological process	9687533
GRAP2	9402	GRB2-related adaptor protein 2	protein binding	Molecular function	12359715
CELF4	56853	CUGBP, Elav-like family member 4	BRE binding	Molecular function	-
CEBPG	1054	CCAAT/enhancer binding protein (C/EBP), gamma	immune response	Biological process	-
CXCL5	6374	chemokine (C-X-C motif) ligand 5	immune response	Biological process	-
IFT81	28981	intraflagellar transport 81	cilium assembly	Biological process	23990561
ETFDH	2110	electron-transferring-flavoprotein dehydrogenase	4 iron, 4 sulfur cluster binding	Molecular function	18037314
COX15	1355	cytochrome c oxidase assembly homolog 15 (yeast)	cytochrome complex	Cellular component	12474143
ZNF350	59348	zinc finger protein 350	nucleus	Cellular component	23665872
CAPNS2	84290	calpain, small subunit 2	cytoplasm	Cellular component	-
PINX1	54984	PIN2/TERF1 interacting, telomerase inhibitor 1	cytoplasm	Cellular component	-
ADGRV1	84059	adhesion G protein-coupled receptor V1	myosin binding	Molecular function	-
SLC7A1	6541	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1	integral component of plasma membrane	Cellular component	1718082
RGL2	5863	ral guanine nucleotide dissociation stimulator-like 2	protein binding	Molecular function	25416956
HLA-DMB	3109	major histocompatibility complex, class II, DM beta	integral component of membrane	Cellular component	-
OR9Q1	219956	olfactory receptor, family 9, subfamily Q, member 1	G-protein coupled receptor signaling pathway	Biological process	-
ZNF384	171017	zinc finger protein 384	nucleus	Cellular component	-
NCOA1	8648	nuclear receptor coactivator 1	hypothalamus development	Biological process	-
SLC9A3R1	9368	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1	filopodium	Cellular component	-
PMM1	5372	phosphomannomutase 1	post-translational protein modification	Biological process	-
LRP4	4038	low density lipoprotein receptor-related protein 4	protein heterotetramerization	Biological process	-
CIDEA	1149	cell death-inducing DFFA-like effector a	negative regulation of cytokine secretion	Biological process	15919794
HSP90AA1	3320	heat shock protein 90kDa alpha (cytosolic), class A member 1	organelle organization	Biological process	-
PPIP5K2	23262	diphosphoinositol pentakisphosphate kinase 2	inositol hexakisphosphate 5-kinase activity	Molecular function	-
NTRK2	4915	neurotrophic tyrosine kinase, receptor, type 2	learning	Biological process	-
IFNA5	3442	interferon, alpha 5	defense response to virus	Biological process	-
SOD3	6649	superoxide dismutase 3, extracellular	extracellular region	Cellular component	-
XDH	7498	xanthine dehydrogenase	small molecule metabolic process	Biological process	-
FGF16	8823	fibroblast growth factor 16	Fc-epsilon receptor signaling pathway	Biological process	-
FBXL4	26235	F-box and leucine-rich repeat protein 4	ubiquitin ligase complex	Cellular component	10531035
RSPH14	27156	radial spoke head 14 homolog (Chlamydomonas)	molecular_function	Molecular function	-
PIP	5304	prolactin-induced protein	actin binding	Molecular function	2013294
HDAC7	51564	histone deacetylase 7	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
HSD3B7	80270	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	bile acid metabolic process	Biological process	-
CNIH1	10175	cornichon family AMPA receptor auxiliary protein 1	signal transduction	Biological process	10209299
ENPP7	339221	ectonucleotide pyrophosphatase/phosphodiesterase 7	sphingomyelin catabolic process	Biological process	-
OR8G3P	387815	olfactory receptor, family 8, subfamily G, member 3 pseudogene	olfactory receptor activity	Molecular function	-
VAMP7	6845	vesicle-associated membrane protein 7	secretory granule	Cellular component	18042464
UXT	8409	ubiquitously-expressed, prefoldin-like chaperone	RNA polymerase II transcription corepressor activity	Molecular function	21730289
CDH11	1009	cadherin 11, type 2, OB-cadherin (osteoblast)	cell adhesion	Biological process	8163513
XRCC4	7518	X-ray repair complementing defective repair in Chinese hamster cells 4	cellular response to lithium ion	Biological process	-
FSHB	2488	follicle stimulating hormone, beta polypeptide	transforming growth factor beta receptor signaling pathway	Biological process	14557487
TAL2	6887	T-cell acute lymphocytic leukemia 2	regulation of transcription from RNA polymerase II promoter	Biological process	-
KCNG3	170850	potassium channel, voltage gated modifier subfamily G, member 3	plasma membrane	Cellular component	-
GALR3	8484	galanin receptor 3	plasma membrane	Cellular component	-
FGF10	2255	fibroblast growth factor 10	cell surface	Cellular component	11923311
PTEN	5728	phosphatase and tensin homolog	negative regulation of synaptic vesicle clustering	Biological process	-
OR52D1	390066	olfactory receptor, family 52, subfamily D, member 1	olfactory receptor activity	Molecular function	11121057
UNC119	9094	unc-119 homolog (C. elegans)	cytosol	Cellular component	9538874
PTPRC	5788	protein tyrosine phosphatase, receptor type, C	focal adhesion	Cellular component	-
IFITM3	10410	interferon induced transmembrane protein 3	protein binding	Molecular function	18486613
STXBP1	6812	syntaxin binding protein 1	mitochondrion	Cellular component	-
MMS19	64210	MMS19 nucleotide excision repair homolog (S. cerevisiae)	response to hormone	Biological process	11279242
ARNT2	9915	aryl-hydrocarbon receptor nuclear translocator 2	positive regulation of cell proliferation	Biological process	-
PRSS8	5652	protease, serine, 8	plasma membrane	Cellular component	19911255
BCL3	602	B-cell CLL/lymphoma 3	follicular dendritic cell differentiation	Biological process	-
FUT9	10690	fucosyltransferase 9 (alpha (1,3) fucosyltransferase)	L-fucose catabolic process	Biological process	11698403
TTPA	7274	tocopherol (alpha) transfer protein	negative regulation of establishment of blood-brain barrier	Biological process	-
TESK2	10420	testis-specific kinase 2	cytoplasm	Cellular component	-
TMEM173	340061	transmembrane protein 173	protein binding	Molecular function	18724357
RFNG	5986	RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity	Molecular function	-
RRP1B	23076	ribosomal RNA processing 1B	heterochromatin	Cellular component	-
CERCAM	51148	cerebral endothelial cell adhesion molecule	movement of cell or subcellular component	Biological process	10608765
NME2	4831	NME/NM23 nucleoside diphosphate kinase 2	protein binding	Molecular function	11919189
SOD2	6648	superoxide dismutase 2, mitochondrial	superoxide dismutase activity	Molecular function	-
HNF1B	6928	HNF1 homeobox B	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity	Molecular function	-
DRD1	1812	dopamine receptor D1	synaptic transmission, dopaminergic	Biological process	-
PIK3R4	30849	phosphoinositide-3-kinase, regulatory subunit 4	ATP binding	Molecular function	-
TUFM	7284	Tu translation elongation factor, mitochondrial	GTPase activity	Molecular function	-
SLC35B2	347734	solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2	xenobiotic metabolic process	Biological process	-
ZNF8	7554	zinc finger protein 8	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
FGF6	2251	fibroblast growth factor 6	extracellular region	Cellular component	-
CLCN5	1184	chloride channel, voltage-sensitive 5	transmembrane transport	Biological process	-
APOA5	116519	apolipoprotein A-V	positive regulation of very-low-density lipoprotein particle remodeling	Biological process	18635818
UBE4A	9354	ubiquitination factor E4A	cytoplasm	Cellular component	-
SDC4	6385	syndecan 4	protein kinase C binding	Molecular function	-
PRKCE	5581	protein kinase C, epsilon	positive regulation of lipid catabolic process	Biological process	-
LAMA3	3909	laminin, alpha 3	endodermal cell differentiation	Biological process	23154389
POLR2C	5432	polymerase (RNA) II (DNA directed) polypeptide C, 33kDa	DNA-directed RNA polymerase II, core complex	Cellular component	9852112
IL1RL2	8808	interleukin 1 receptor-like 2	interleukin-1-mediated signaling pathway	Biological process	-
FOSL1	8061	FOS-like antigen 1	vitellogenesis	Biological process	-
NEUROD2	4761	neuronal differentiation 2	positive regulation of synaptic plasticity	Biological process	-
CX3CR1	1524	chemokine (C-X3-C motif) receptor 1	negative regulation of cell migration	Biological process	-
PCF11	51585	PCF11 cleavage and polyadenylation factor subunit	mRNA cleavage factor complex	Cellular component	11060040
SLC16A10	117247	solute carrier family 16 (aromatic amino acid transporter), member 10	ion transport	Biological process	-
ZFHX4	79776	zinc finger homeobox 4	transcription, DNA-templated	Biological process	-
FOLR1	2348	folate receptor 1 (adult)	receptor activity	Molecular function	10633085
EOMES	8320	eomesodermin	cerebral cortex regionalization	Biological process	-
CLEC5A	23601	C-type lectin domain family 5, member A	osteoblast development	Biological process	-
KCNJ10	3766	potassium channel, inwardly rectifying subfamily J, member 10	identical protein binding	Molecular function	-
PDE3A	5139	phosphodiesterase 3A, cGMP-inhibited	cGMP-mediated signaling	Biological process	17704206
PTPRZ1	5803	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	protein dephosphorylation	Biological process	1323835
SLC30A5	64924	solute carrier family 30 (zinc transporter), member 5	regulation of proton transport	Biological process	11937503
MRC1	4360	mannose receptor, C type 1	cellular response to lipopolysaccharide	Biological process	-
SMR3B	10879	submaxillary gland androgen regulated protein 3B	biological_process	Biological process	-
OR5D18	219438	olfactory receptor, family 5, subfamily D, member 18	olfactory receptor activity	Molecular function	-
MED30	90390	mediator complex subunit 30	stem cell maintenance	Biological process	-
MAP3K11	4296	mitogen-activated protein kinase kinase kinase 11	protein tyrosine kinase activity	Molecular function	-
APTX	54840	aprataxin	response to hydrogen peroxide	Biological process	15044383
EGF	1950	epidermal growth factor	phosphatidylinositol-mediated signaling	Biological process	-
RBPJ	3516	recombination signal binding protein for immunoglobulin kappa J region	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	-
CNGB1	1258	cyclic nucleotide gated channel beta 1	regulation of rhodopsin mediated signaling pathway	Biological process	-
ATG7	10533	autophagy related 7	cerebral cortex development	Biological process	-
CFAP126	257177	cilia and flagella associated protein 126	cytoplasm	Cellular component	-
HDAC2	3066	histone deacetylase 2	negative regulation of transcription from RNA polymerase II promoter	Biological process	19041327
SLX1B	79008	SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)	metal ion binding	Molecular function	-
VPS25	84313	vacuolar protein sorting 25 homolog (S. cerevisiae)	regulation of viral life cycle	Biological process	16973552
GTF2B	2959	general transcription factor IIB	protein binding	Molecular function	10330164
PHACTR4	65979	phosphatase and actin regulator 4	actin binding	Molecular function	-
ARHGDIA	396	Rho GDP dissociation inhibitor (GDI) alpha	positive regulation of axonogenesis	Biological process	-
LATS2	26524	large tumor suppressor kinase 2	spindle pole	Cellular component	12853976
PTGS2	5743	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	nucleus	Cellular component	-
RTKN2	219790	rhotekin 2	hemopoiesis	Biological process	-
HLCS	3141	holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)	small molecule metabolic process	Biological process	-
TSC1	7248	tuberous sclerosis 1	myelination	Biological process	-
C4orf48	401115	chromosome 4 open reading frame 48	extracellular region	Cellular component	-
THPO	7066	thrombopoietin	thrombopoietin-mediated signaling pathway	Biological process	-
CENPT	80152	centromere protein T	cell division	Biological process	-
ATP5F1	515	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1	nucleus	Cellular component	21630459
FBL	2091	fibrillarin	poly(A) RNA binding	Molecular function	22658674
TICAM2	353376	toll-like receptor adaptor molecule 2	Golgi apparatus	Cellular component	-
KIR2DS1	3806	killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1	innate immune response	Biological process	-
RASSF9	9182	Ras association (RalGDS/AF-6) domain family (N-terminal) member 9	cytosol	Cellular component	9837933
NUP85	79902	nucleoporin 85kDa	small GTPase mediated signal transduction	Biological process	-
C14orf39	317761	chromosome 14 open reading frame 39	multicellular organismal development	Biological process	-
PAH	5053	phenylalanine hydroxylase	extracellular exosome	Cellular component	23376485
POM121C	100101267	POM121 transmembrane nucleoporin C	protein binding	Molecular function	17577209
GTF2H3	2967	general transcription factor IIH, polypeptide 3, 34kDa	transcription elongation from RNA polymerase I promoter	Biological process	-
EFNA1	1942	ephrin-A1	axon guidance	Biological process	-
TRPM7	54822	transient receptor potential cation channel, subfamily M, member 7	protein serine/threonine kinase activity	Molecular function	-
SV2B	9899	synaptic vesicle glycoprotein 2B	protein binding	Molecular function	25416956
MSH2	4436	mutS homolog 2	MutSalpha complex	Cellular component	23622243
SIRT2	22933	sirtuin 2	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
PRNP	5621	prion protein	negative regulation of apoptotic process	Biological process	-
MYL6	4637	myosin, light chain 6, alkali, smooth muscle and non-muscle	extracellular exosome	Cellular component	20458337
IFT172	26160	intraflagellar transport 172	positive regulation of smoothened signaling pathway	Biological process	-
CHST11	50515	carbohydrate (chondroitin 4) sulfotransferase 11	chondroitin sulfate metabolic process	Biological process	-
GRIN3B	116444	glutamate receptor, ionotropic, N-methyl-D-aspartate 3B	N-methyl-D-aspartate selective glutamate receptor activity	Molecular function	-
GLMN	11146	glomulin, FKBP associated protein	positive regulation of interleukin-2 biosynthetic process	Biological process	12604780
CD58	965	CD58 molecule	cellular response to interferon-gamma	Biological process	19109405
CDH16	1014	cadherin 16, KSP-cadherin	cell adhesion	Biological process	9721215
PRKDC	5591	protein kinase, DNA-activated, catalytic polypeptide	T cell differentiation in thymus	Biological process	-
NME2	4831	NME/NM23 nucleoside diphosphate kinase 2	peptidyl-histidine phosphorylation	Biological process	-
BAD	572	BCL2-associated agonist of cell death	positive regulation of mitochondrial membrane potential	Biological process	-
IL4	3565	interleukin 4	protein binding	Molecular function	10219247
NTN1	9423	netrin 1	protein binding	Molecular function	10102268
FGF7	2252	fibroblast growth factor 7	positive regulation of epithelial cell proliferation involved in lung morphogenesis	Biological process	9740653
TADA3	10474	transcriptional adaptor 3	mitotic nuclear division	Biological process	-
PNMA3	29944	paraneoplastic Ma antigen 3	zinc ion binding	Molecular function	-
DOK6	220164	docking protein 6	insulin receptor binding	Molecular function	-
STK11	6794	serine/threonine kinase 11	regulation of Wnt signaling pathway	Biological process	-
HS6ST1	9394	heparan sulfate 6-O-sulfotransferase 1	heparan sulfate 6-O-sulfotransferase activity	Molecular function	-
ATP5D	513	ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit	cellular metabolic process	Biological process	-
TP53	7157	tumor protein p53	regulation of apoptotic process	Biological process	14744935
CORO1A	11151	coronin, actin binding protein, 1A	early endosome to recycling endosome transport	Biological process	-
HIST1H4I	8294	histone cluster 1, H4i	protein heterotetramerization	Biological process	20498094
SERPINB13	5275	serpin peptidase inhibitor, clade B (ovalbumin), member 13	regulation of proteolysis	Biological process	10512713
IFNGR1	3459	interferon gamma receptor 1	regulation of interferon-gamma-mediated signaling pathway	Biological process	-
PPP1R11	6992	protein phosphatase 1, regulatory (inhibitor) subunit 11	protein binding	Molecular function	9843442
PP2D1	151649	protein phosphatase 2C-like domain containing 1	metabolic process	Biological process	-
CELF4	56853	CUGBP, Elav-like family member 4	positive regulation of mRNA splicing, via spliceosome	Biological process	15009664
CHI3L1	1116	chitinase 3-like 1 (cartilage glycoprotein-39)	extracellular matrix structural constituent	Molecular function	8245017
ERMP1	79956	endoplasmic reticulum metallopeptidase 1	membrane	Cellular component	19946888
CARD10	29775	caspase recruitment domain family, member 10	protein binding	Molecular function	11259443
HIST1H4K	8362	histone cluster 1, H4k	negative regulation of gene expression, epigenetic	Biological process	-
EIF4A2	1974	eukaryotic translation initiation factor 4A2	cytosol	Cellular component	-
TMEM39B	55116	transmembrane protein 39B	integral component of membrane	Cellular component	-
UBE2V2	7336	ubiquitin-conjugating enzyme E2 variant 2	negative regulation of neuron apoptotic process	Biological process	-
RYR2	6262	ryanodine receptor 2 (cardiac)	regulation of cardiac muscle contraction	Biological process	11159936
SMAD5	4090	SMAD family member 5	transcription factor complex	Cellular component	-
YAP1	10413	Yes-associated protein 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
PRSS3	5646	protease, serine, 3	cobalamin metabolic process	Biological process	-
FGF10	2255	fibroblast growth factor 10	extracellular region	Cellular component	-
PLB1	151056	phospholipase B1	phospholipid metabolic process	Biological process	-
CD2	914	CD2 molecule	external side of plasma membrane	Cellular component	21460847
HDAC3	8841	histone deacetylase 3	circadian regulation of gene expression	Biological process	-
G3BP1	10146	GTPase activating protein (SH3 domain) binding protein 1	cytoplasm	Cellular component	-
MPO	4353	myeloperoxidase	defense response	Biological process	8621627
TF	7018	transferrin	platelet activation	Biological process	-
MRPL47	57129	mitochondrial ribosomal protein L47	structural constituent of ribosome	Molecular function	-
NAPRT	93100	nicotinate phosphoribosyltransferase	nicotinate nucleotide salvage	Biological process	-
EGF	1950	epidermal growth factor	innate immune response	Biological process	-
IRF2BP1	26145	interferon regulatory factor 2 binding protein 1	protein binding	Molecular function	18671972
CALM3	808	calmodulin 3 (phosphorylase kinase, delta)	extracellular region	Cellular component	-
VIP	7432	vasoactive intestinal peptide	regulation of signal transduction	Biological process	-
ZNF669	79862	zinc finger protein 669	transcription, DNA-templated	Biological process	-
ZMYND15	84225	zinc finger, MYND-type containing 15	transcription, DNA-templated	Biological process	-
NCF1C	654817	neutrophil cytosolic factor 1C pseudogene	cytoplasm	Cellular component	-
PRLHR	2834	prolactin releasing hormone receptor	protein binding	Molecular function	11641419
NONO	4841	non-POU domain containing, octamer-binding	DNA repair	Biological process	-
SEMA4G	57715	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G	cell differentiation	Biological process	-
NEFL	4747	neurofilament, light polypeptide	axon transport of mitochondrion	Biological process	15857389
AGTR1	185	angiotensin II receptor, type 1	angiotensin type II receptor activity	Molecular function	15611106
TP63	8626	tumor protein p63	positive regulation of Notch signaling pathway	Biological process	11641404
RBBP5	5929	retinoblastoma binding protein 5	methylated histone binding	Molecular function	15960975
CETP	1071	cholesteryl ester transfer protein, plasma	triglyceride binding	Molecular function	2833496
EDIL3	10085	EGF-like repeats and discoidin I-like domains 3	positive regulation of cell-substrate adhesion	Biological process	-
SMTNL1	219537	smoothelin-like 1	nucleus	Cellular component	-
ERVK13-1	100507321	endogenous retrovirus group K13, member 1	structural molecule activity	Molecular function	-
OR1L1	26737	olfactory receptor, family 1, subfamily L, member 1	G-protein coupled receptor signaling pathway	Biological process	-
CLCN3	1182	chloride channel, voltage-sensitive 3	Golgi membrane	Cellular component	-
FAM74A1	401507	family with sequence similarity 74, member A1	protein binding	Molecular function	25416956
SCN1B	6324	sodium channel, voltage gated, type I beta subunit	membrane depolarization during Purkinje myocyte cell action potential	Biological process	18464934
ATP8B3	148229	ATPase, aminophospholipid transporter, class I, type 8B, member 3	ATP binding	Molecular function	-
ANXA8	653145	annexin A8	actin filament binding	Molecular function	16638567
RFFL	117584	ring finger and FYVE-like domain containing E3 ubiquitin protein ligase	negative regulation of tumor necrosis factor-mediated signaling pathway	Biological process	18450452
FSHB	2488	follicle stimulating hormone, beta polypeptide	positive regulation of cell migration	Biological process	20613903
ANGPT1	284	angiopoietin 1	positive regulation of endothelial cell migration	Biological process	12958144
SLC8A1	6546	solute carrier family 8 (sodium/calcium exchanger), member 1	cellular response to caffeine	Biological process	-
IRS2	8660	insulin receptor substrate 2	brain development	Biological process	-
KDM6B	23135	lysine (K)-specific demethylase 6B	sequence-specific DNA binding	Molecular function	-
CALM1	801	calmodulin 1 (phosphorylase kinase, delta)	regulation of heart rate	Biological process	23040497
MFN2	9927	mitofusin 2	mitochondrial membrane organization	Biological process	11181170
ABCD4	5826	ATP-binding cassette, sub-family D (ALD), member 4	small molecule metabolic process	Biological process	-
EPHB2	2048	EPH receptor B2	positive regulation of long-term neuronal synaptic plasticity	Biological process	-
PDK2	5164	pyruvate dehydrogenase kinase, isozyme 2	ATP binding	Molecular function	16401071
ESYT3	83850	extended synaptotagmin-like protein 3	lipid transport	Biological process	-
RELA	5970	v-rel avian reticuloendotheliosis viral oncogene homolog A	negative regulation of transcription from RNA polymerase II promoter	Biological process	17350185
RFFL	117584	ring finger and FYVE-like domain containing E3 ubiquitin protein ligase	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological process	18382127
TFF1	7031	trefoil factor 1	growth factor activity	Molecular function	-
NOTCH4	4855	notch 4	cell differentiation	Biological process	11823422
OIP5	11339	Opa interacting protein 5	mitotic nuclear division	Biological process	-
HRK	8739	harakiri, BCL2 interacting protein	protein binding	Molecular function	14596824
WFDC12	128488	WAP four-disulfide core domain 12	extracellular region	Cellular component	-
CYP11B1	1584	cytochrome P450, family 11, subfamily B, polypeptide 1	sterol metabolic process	Biological process	-
CTNNBIP1	56998	catenin, beta interacting protein 1	negative regulation of smooth muscle cell proliferation	Biological process	-
ATP5I	521	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E	mitochondrion	Cellular component	-
CARD16	114769	caspase recruitment domain family, member 16	cysteine-type endopeptidase inhibitor activity	Molecular function	-
PSMF1	9491	proteasome (prosome, macropain) inhibitor subunit 1 (PI31)	negative regulation of canonical Wnt signaling pathway	Biological process	-
COBL	23242	cordon-bleu WH2 repeat protein	axon	Cellular component	-
IFNGR1	3459	interferon gamma receptor 1	postsynaptic density	Cellular component	-
UBR3	130507	ubiquitin protein ligase E3 component n-recognin 3 (putative)	olfactory behavior	Biological process	-
MLXIPL	51085	MLX interacting protein-like	negative regulation of transcription, DNA-templated	Biological process	11230181
TRAK2	66008	trafficking protein, kinesin binding 2	cytoplasm	Cellular component	-
PAK1	5058	p21 protein (Cdc42/Rac)-activated kinase 1	dendrite development	Biological process	-
KLB	152831	klotho beta	innate immune response	Biological process	-
TCL1A	8115	T-cell leukemia/lymphoma 1A	pronucleus	Cellular component	-
SUV39H1	6839	suppressor of variegation 3-9 homolog 1 (Drosophila)	histone H3-K9 dimethylation	Biological process	-
OXT	5020	oxytocin/neurophysin I prepropeptide	response to glucocorticoid	Biological process	-
KMO	8564	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	response to salt stress	Biological process	10672018
RNF144B	255488	ring finger protein 144B	ligase activity	Molecular function	-
ACOT7	11332	acyl-CoA thioesterase 7	nucleoplasm	Cellular component	-
HOXC13	3229	homeobox C13	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
GPR27	2850	G protein-coupled receptor 27	plasma membrane	Cellular component	-
AP1AR	55435	adaptor-related protein complex 1 associated regulatory protein	late endosome	Cellular component	-
AQP10	89872	aquaporin 10	glycerol channel activity	Molecular function	-
MAGEC2	51438	melanoma antigen family C2	positive regulation of ubiquitin-protein transferase activity	Biological process	20864041
TCFL5	10732	transcription factor-like 5 (basic helix-loop-helix)	multicellular organismal development	Biological process	-
BCO2	83875	beta-carotene oxygenase 2	metal ion binding	Molecular function	-
GSTP1	2950	glutathione S-transferase pi 1	kinase regulator activity	Molecular function	-
EXOSC7	23016	exosome component 7	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	Biological process	-
AFTPH	54812	aftiphilin	cytosol	Cellular component	15758025
INO80E	283899	INO80 complex subunit E	nucleolus	Cellular component	-
UBB	7314	ubiquitin B	antigen processing and presentation of exogenous peptide antigen via MHC class I	Biological process	-
FGD3	89846	FYVE, RhoGEF and PH domain containing 3	actin cytoskeleton organization	Biological process	-
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	positive regulation of epithelial cell proliferation involved in prostate gland development	Biological process	-
LASP1	3927	LIM and SH3 protein 1	extracellular exosome	Cellular component	23376485
CDK4	1019	cyclin-dependent kinase 4	perinuclear region of cytoplasm	Cellular component	-
HNF1B	6928	HNF1 homeobox B	hindbrain development	Biological process	-
COX5A	9377	cytochrome c oxidase subunit Va	mitochondrial inner membrane	Cellular component	-
PEPD	5184	peptidase D	aminopeptidase activity	Molecular function	-
CDK5RAP1	51654	CDK5 regulatory subunit associated protein 1	negative regulation of cyclin-dependent protein serine/threonine kinase activity	Biological process	11882646
ZNF365	22891	zinc finger protein 365	cytoplasm	Cellular component	-
LUM	4060	lumican	protein binding	Molecular function	25304424
APOC1	341	apolipoprotein C-I	fatty acid binding	Molecular function	17339654
SLC9A3R1	9368	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1	PDZ domain binding	Molecular function	16236806
EPHX1	2052	epoxide hydrolase 1, microsomal (xenobiotic)	cis-stilbene-oxide hydrolase activity	Molecular function	-
SOD2	6648	superoxide dismutase 2, mitochondrial	manganese ion binding	Molecular function	10511315
PXYLP1	92370	2-phosphoxylose phosphatase 1	positive regulation of heparan sulfate proteoglycan biosynthetic process	Biological process	24425863
LMTK3	114783	lemur tyrosine kinase 3	molecular_function	Molecular function	-
IGHA2	3494	immunoglobulin heavy constant alpha 2 (A2m marker)	immune response	Biological process	2241915
NLGN1	22871	neuroligin 1	N-methyl-D-aspartate selective glutamate receptor complex	Cellular component	-
MAP3K13	9175	mitogen-activated protein kinase kinase kinase 13	metal ion binding	Molecular function	-
SPHK1	8877	sphingosine kinase 1	positive regulation of protein ubiquitination	Biological process	20577214
BAD	572	BCL2-associated agonist of cell death	response to drug	Biological process	-
PHF21A	51317	PHD finger protein 21A	nucleoplasm	Cellular component	-
ALPK2	115701	alpha-kinase 2	protein serine/threonine kinase activity	Molecular function	-
CTSH	1512	cathepsin H	cytosol	Cellular component	9050938
GNL3	26354	guanine nucleotide binding protein-like 3 (nucleolar)	nucleolus	Cellular component	-
SLC16A5	9121	solute carrier family 16 (monocarboxylate transporter), member 5	lactate transmembrane transporter activity	Molecular function	-
MOB4	25843	MOB family member 4, phocein	metal ion binding	Molecular function	-
PHKG1	5260	phosphorylase kinase, gamma 1 (muscle)	phosphorylase kinase activity	Molecular function	-
SMS	6611	spermine synthase	spermine biosynthetic process	Biological process	-
PAK6	56924	p21 protein (Cdc42/Rac)-activated kinase 6	protein binding	Molecular function	24510904
RPL14	9045	ribosomal protein L14	viral transcription	Biological process	-
BRCA2	675	breast cancer 2, early onset	centrosome	Cellular component	17286961
AP4M1	9179	adaptor-related protein complex 4, mu 1 subunit	transporter activity	Molecular function	10066790
DUS2	54920	dihydrouridine synthase 2	flavin adenine dinucleotide binding	Molecular function	-
CCBL2	56267	cysteine conjugate-beta lyase 2	pyridoxal phosphate binding	Molecular function	-
MED30	90390	mediator complex subunit 30	intracellular steroid hormone receptor signaling pathway	Biological process	11867769
LOC440786	440786	uncharacterized LOC440786	Fc-gamma receptor signaling pathway involved in phagocytosis	Biological process	-
TUSC2	11334	tumor suppressor candidate 2	positive regulation of interleukin-10 production	Biological process	-
FECH	2235	ferrochelatase	response to methylmercury	Biological process	-
RFC5	5985	replication factor C (activator 1) 5, 36.5kDa	DNA repair	Biological process	-
TMPRSS15	5651	transmembrane protease, serine 15	serine-type endopeptidase activity	Molecular function	-
AXIN1	8312	axin 1	positive regulation of peptidyl-serine phosphorylation	Biological process	18593713
VPS37D	155382	vacuolar protein sorting 37 homolog D (S. cerevisiae)	intracellular transport of virus	Biological process	-
ACTN4	81	actinin, alpha 4	ligand-dependent nuclear receptor transcription coactivator activity	Molecular function	22351778
HOXC9	3225	homeobox C9	embryonic skeletal system morphogenesis	Biological process	-
CAP2	10486	CAP, adenylate cyclase-associated protein, 2 (yeast)	signal transduction	Biological process	7962207
KCTD19	146212	potassium channel tetramerization domain containing 19	protein homooligomerization	Biological process	-
CENPC	1060	centromere protein C	nucleus	Cellular component	-
MCU	90550	mitochondrial calcium uniporter	uniplex complex	Cellular component	22925203
PPP5C	5536	protein phosphatase 5, catalytic subunit	protein serine/threonine phosphatase activity	Molecular function	7925273
TMEM178B	100507421	transmembrane protein 178B	integral component of membrane	Cellular component	-
KIF3C	3797	kinesin family member 3C	antigen processing and presentation of exogenous peptide antigen via MHC class II	Biological process	-
TBC1D7	51256	TBC1 domain family, member 7	negative regulation of cilium assembly	Biological process	17646400
PSG7	5676	pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene)	female pregnancy	Biological process	1690992
EPB42	2038	erythrocyte membrane protein band 4.2	protein binding	Molecular function	12646258
DOLPP1	57171	dolichyldiphosphatase 1	protein N-linked glycosylation via asparagine	Biological process	-
MALL	7851	mal, T-cell differentiation protein-like	cholesterol homeostasis	Biological process	11294831
KAT6B	23522	K(lysine) acetyltransferase 6B	negative regulation of transcription, DNA-templated	Biological process	10497217
SPINT2	10653	serine peptidase inhibitor, Kunitz type, 2	cytoplasm	Cellular component	11606055
TEK	7010	TEK tyrosine kinase, endothelial	angiogenesis	Biological process	-
OR8H3	390152	olfactory receptor, family 8, subfamily H, member 3	G-protein coupled receptor signaling pathway	Biological process	-
LRAT	9227	lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)	rough endoplasmic reticulum	Cellular component	-
POLR2D	5433	polymerase (RNA) II (DNA directed) polypeptide D	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	Biological process	-
DDN	23109	dendrin	perikaryon	Cellular component	-
LSG1	55341	large 60S subunit nuclear export GTPase 1	GTP binding	Molecular function	16209721
ITGA8	8516	integrin, alpha 8	extracellular matrix organization	Biological process	-
INSRR	3645	insulin receptor-related receptor	protein autophosphorylation	Biological process	21641549
HIST2H4B	554313	histone cluster 2, H4b	DNA replication-independent nucleosome assembly	Biological process	14718166
OR6C70	390327	olfactory receptor, family 6, subfamily C, member 70	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
HLA-B	3106	major histocompatibility complex, class I, B	receptor binding	Molecular function	20008523
SPEG	10290	SPEG complex locus	protein phosphorylation	Biological process	-
IL1R1	3554	interleukin 1 receptor, type I	protein binding	Molecular function	12925853
AEBP1	165	AE binding protein 1	proteolysis	Biological process	-
CTNNBL1	56259	catenin, beta like 1	spliceosomal complex	Cellular component	20176811
ALDOA	226	aldolase A, fructose-bisphosphate	small molecule metabolic process	Biological process	-
RAB39A	54734	RAB39A, member RAS oncogene family	phagocytic vesicle	Cellular component	21255211
OR4F17	81099	olfactory receptor, family 4, subfamily F, member 17	plasma membrane	Cellular component	-
HSD17B2	3294	hydroxysteroid (17-beta) dehydrogenase 2	placenta development	Biological process	-
ABCB9	23457	ATP-binding cassette, sub-family B (MDR/TAP), member 9	peptide transport	Biological process	17977821
TP53INP1	94241	tumor protein p53 inducible nuclear protein 1	nucleus	Cellular component	22470510
ITGA2B	3674	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	integral component of plasma membrane	Cellular component	2439501
ETV5	2119	ets variant 5	neuromuscular synaptic transmission	Biological process	-
CASP7	840	caspase 7, apoptosis-related cysteine peptidase	execution phase of apoptosis	Biological process	-
SLC44A1	23446	solute carrier family 44 (choline transporter), member 1	glycerophospholipid biosynthetic process	Biological process	-
SPPL2B	56928	signal peptide peptidase like 2B	regulation of immune response	Biological process	16829952
LRP8	7804	low density lipoprotein receptor-related protein 8, apolipoprotein e receptor	very-low-density lipoprotein particle receptor activity	Molecular function	8626535
EMILIN3	90187	elastin microfibril interfacer 3	cytoplasm	Cellular component	-
KCNH1	3756	potassium channel, voltage gated eag related subfamily H, member 1	regulation of ion transmembrane transport	Biological process	-
GPD1L	23171	glycerol-3-phosphate dehydrogenase 1-like	ion channel binding	Molecular function	19666841
GRPR	2925	gastrin-releasing peptide receptor	cell proliferation	Biological process	1655761
TMX4	56255	thioredoxin-related transmembrane protein 4	oxidation-reduction process	Biological process	-
YWHAG	7532	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma	G2/M transition of mitotic cell cycle	Biological process	-
TRAF2	7186	TNF receptor-associated factor 2	cytosol	Cellular component	-
PRCP	5547	prolylcarboxypeptidase (angiotensinase C)	regulation of thyroid hormone mediated signaling pathway	Biological process	-
GFPT1	2673	glutamine--fructose-6-phosphate transaminase 1	cytosol	Cellular component	-
SNPH	9751	syntaphilin	cytoplasm	Cellular component	15459722
GRIN1	2902	glutamate receptor, ionotropic, N-methyl D-aspartate 1	glycine binding	Molecular function	17047094
KCNG2	26251	potassium channel, voltage gated modifier subfamily G, member 2	protein homooligomerization	Biological process	-
ASXL3	80816	additional sex combs like transcriptional regulator 3	regulation of transcription, DNA-templated	Biological process	-
TSHZ3	57616	teashirt zinc finger homeobox 3	kidney morphogenesis	Biological process	-
C1QL1	10882	complement component 1, q subcomponent-like 1	extracellular region	Cellular component	-
MAPK13	5603	mitogen-activated protein kinase 13	protein serine/threonine kinase activity	Molecular function	12244047
PI4KA	5297	phosphatidylinositol 4-kinase, catalytic, alpha	cytoplasm	Cellular component	-
MYCBP	26292	MYC binding protein	mitochondrion	Cellular component	-
TEAD4	7004	TEA domain family member 4	sequence-specific DNA binding transcription factor activity	Molecular function	18579750
PIK3CB	5291	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta	regulation of cell-matrix adhesion	Biological process	25139353
FCGR1B	2210	Fc fragment of IgG, high affinity Ib, receptor (CD64)	immunoglobulin receptor activity	Molecular function	1430234
NPHS1	4868	nephrosis 1, congenital, Finnish type (nephrin)	glomerular visceral epithelial cell development	Biological process	17464107
VPS25	84313	vacuolar protein sorting 25 homolog (S. cerevisiae)	structural molecule activity	Molecular function	-
GABPB1	2553	GA binding protein transcription factor, beta subunit 1	transcription, DNA-templated	Biological process	-
CLCA1	1179	chloride channel accessory 1	calcium ion transport	Biological process	-
TSSK3	81629	testis-specific serine kinase 3	spermatogenesis	Biological process	-
ATF4	468	activating transcription factor 4	positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance	Biological process	14685163
SOS1	6654	son of sevenless homolog 1 (Drosophila)	blood coagulation	Biological process	-
FAM169A	26049	family with sequence similarity 169, member A	nuclear inner membrane	Cellular component	-
IFT88	8100	intraflagellar transport 88	response to fluid shear stress	Biological process	-
GOLPH3	64083	golgi phosphoprotein 3 (coat-protein)	protein secretion	Biological process	23500462
TNXB	7148	tenascin XB	proteinaceous extracellular matrix	Cellular component	7686164
VEGFA	7422	vascular endothelial growth factor A	regulation of cGMP metabolic process	Biological process	16150726
PSME3	10197	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)	apoptotic process	Biological process	-
KCNJ8	3764	potassium channel, inwardly rectifying subfamily J, member 8	inward rectifier potassium channel activity	Molecular function	7890693
MAPK11	5600	mitogen-activated protein kinase 11	transcription, DNA-templated	Biological process	-
RBM14	10432	RNA binding motif protein 14	nucleotide binding	Molecular function	-
AGT	183	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	positive regulation of nitric oxide biosynthetic process	Biological process	-
PTOV1	53635	prostate tumor overexpressed 1	plasma membrane	Cellular component	-
DDX17	10521	DEAD (Asp-Glu-Ala-Asp) box helicase 17	nucleoplasm	Cellular component	-
HJURP	55355	Holliday junction recognition protein	condensed chromosome kinetochore	Cellular component	19410545
OR8K5	219453	olfactory receptor, family 8, subfamily K, member 5	G-protein coupled receptor signaling pathway	Biological process	-
SGSM3	27352	small G protein signaling modulator 3	cytosol	Cellular component	17562788
TNFRSF11B	4982	tumor necrosis factor receptor superfamily, member 11b	signal transduction	Biological process	-
ZBTB49	166793	zinc finger and BTB domain containing 49	metal ion binding	Molecular function	-
HIATL1	84641	hippocampus abundant transcript-like 1	transmembrane transport	Biological process	-
WNT4	54361	wingless-type MMTV integration site family, member 4	liver development	Biological process	15312687
TLX3	30012	T-cell leukemia homeobox 3	regulation of respiratory gaseous exchange by neurological system process	Biological process	-
CLCF1	23529	cardiotrophin-like cytokine factor 1	growth factor activity	Molecular function	14632778
STK38	11329	serine/threonine kinase 38	protein phosphorylation	Biological process	12493777
WAPAL	23063	wings apart-like homolog (Drosophila)	cytosol	Cellular component	-
ECE1	1889	endothelin converting enzyme 1	ear development	Biological process	9915973
LCOR	84458	ligand dependent nuclear receptor corepressor	nucleus	Cellular component	-
METTL21EP	121952	methyltransferase like 21E, pseudogene	methyltransferase activity	Molecular function	-
NRXN1	9378	neurexin 1	metal ion binding	Molecular function	-
AGPAT3	56894	1-acylglycerol-3-phosphate O-acyltransferase 3	small molecule metabolic process	Biological process	-
ANXA1	301	annexin A1	alpha-beta T cell differentiation	Biological process	-
ANKFY1	51479	ankyrin repeat and FYVE domain containing 1	lysosomal membrane	Cellular component	17897319
B4GALT7	11285	xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7	extracellular matrix	Cellular component	16583246
UMODL1	89766	uromodulin-like 1	calcium ion binding	Molecular function	-
ERBB2	2064	erb-b2 receptor tyrosine kinase 2	heart development	Biological process	-
MZT1	440145	mitotic spindle organizing protein 1	gamma-tubulin ring complex	Cellular component	20360068
MBD3	53615	methyl-CpG binding domain protein 3	methylation-dependent chromatin silencing	Biological process	-
MMP24	10893	matrix metallopeptidase 24 (membrane-inserted)	proteolysis	Biological process	-
POLD1	5424	polymerase (DNA directed), delta 1, catalytic subunit	cytoplasm	Cellular component	-
TRUB1	142940	TruB pseudouridine (psi) synthase family member 1	pseudouridine synthase activity	Molecular function	-
NCK1	4690	NCK adaptor protein 1	protein binding, bridging	Molecular function	16835242
OR10J4	391121	olfactory receptor, family 10, subfamily J, member 4 (gene/pseudogene)	olfactory receptor activity	Molecular function	-
CXCL8	3576	chemokine (C-X-C motif) ligand 8	immune response	Biological process	-
ATXN1	6310	ataxin 1	chromatin binding	Molecular function	-
NOX4	50507	NADPH oxidase 4	positive regulation of ERK1 and ERK2 cascade	Biological process	-
EHD3	30845	EH-domain containing 3	ATP binding	Molecular function	-
RPS6KA5	9252	ribosomal protein S6 kinase, 90kDa, polypeptide 5	positive regulation of histone phosphorylation	Biological process	20018936
MMAB	326625	methylmalonic aciduria (cobalamin deficiency) cblB type	cobalamin biosynthetic process	Biological process	-
PLEKHG5	57449	pleckstrin homology domain containing, family G (with RhoGef domain) member 5	positive regulation of apoptotic process	Biological process	-
DEF8	54849	differentially expressed in FDCP 8 homolog (mouse)	zinc ion binding	Molecular function	-
CD58	965	CD58 molecule	positive regulation of interleukin-8 secretion	Biological process	19109405
HLA-DRB3	3125	major histocompatibility complex, class II, DR beta 3	late endosome membrane	Cellular component	18305173
ETV7	51513	ets variant 7	protein binding	Molecular function	12588862
DCHS1	8642	dachsous cadherin-related 1	branching involved in ureteric bud morphogenesis	Biological process	-
RAB35	11021	RAB35, member RAS oncogene family	GTPase activity	Molecular function	17562788
ARAF	369	A-Raf proto-oncogene, serine/threonine kinase	positive regulation of peptidyl-serine phosphorylation	Biological process	19667065
ATL1	51062	atlastin GTPase 1	Golgi apparatus	Cellular component	-
CLEC4D	338339	C-type lectin domain family 4, member D	plasma membrane	Cellular component	-
TCF3	6929	transcription factor 3	positive regulation of cell cycle	Biological process	11509675
KCNK5	8645	potassium channel, two pore domain subfamily K, member 5	integral component of plasma membrane	Cellular component	9812978
TPR	7175	translocated promoter region, nuclear basket protein	mitotic spindle	Cellular component	20133940
SLC17A7	57030	solute carrier family 17 (vesicular glutamate transporter), member 7	presynaptic active zone	Cellular component	-
SNX6	58533	sorting nexin 6	cytoplasmic membrane-bounded vesicle	Cellular component	-
RP1	6101	retinitis pigmentosa 1 (autosomal dominant)	axoneme assembly	Biological process	-
NPPA	4878	natriuretic peptide A	negative regulation of systemic arterial blood pressure	Biological process	-
FUZ	80199	fuzzy planar cell polarity protein	cytoplasm	Cellular component	-
CDRT15P2	644694	CMT1A duplicated region transcript 15 pseudogene 2	integral component of membrane	Cellular component	-
ANG	283	angiogenin, ribonuclease, RNase A family, 5	receptor binding	Molecular function	9122172
CSNK2B	1460	casein kinase 2, beta polypeptide	PcG protein complex	Cellular component	21282530
DPH2	1802	DPH2 homolog (S. cerevisiae)	cytosol	Cellular component	-
SLC26A3	1811	solute carrier family 26 (anion exchanger), member 3	sulfate transmembrane transport	Biological process	-
STAT6	6778	signal transducer and activator of transcription 6, interleukin-4 induced	nucleoplasm	Cellular component	-
AFP	174	alpha-fetoprotein	progesterone metabolic process	Biological process	-
CLIC1	1192	chloride intracellular channel 1	brush border	Cellular component	10793131
KIAA1429	25962	KIAA1429	MIS complex	Cellular component	24981863
IFNA4	3441	interferon, alpha 4	response to virus	Biological process	3891272
PDK2	5164	pyruvate dehydrogenase kinase, isozyme 2	insulin receptor signaling pathway	Biological process	-
CCM2	83605	cerebral cavernous malformation 2	venous blood vessel morphogenesis	Biological process	-
HAL	3034	histidine ammonia-lyase	histidine ammonia-lyase activity	Molecular function	-
DNAJA3	9093	DnaJ (Hsp40) homolog, subfamily A, member 3	NF-kappaB binding	Molecular function	15601829
BECN1	8678	beclin 1, autophagy related	phagocytic vesicle	Cellular component	-
FLNC	2318	filamin C, gamma	muscle fiber development	Biological process	-
NGDN	25983	neuroguidin, EIF4E binding protein	dendrite	Cellular component	-
OTC	5009	ornithine carbamoyltransferase	ornithine carbamoyltransferase activity	Molecular function	2556444
GDF10	2662	growth differentiation factor 10	cytokine activity	Molecular function	-
CLCA2	9635	chloride channel accessory 2	extracellular region	Cellular component	-
BDH2	56898	3-hydroxybutyrate dehydrogenase, type 2	fatty acid beta-oxidation	Biological process	16380372
ARL3	403	ADP-ribosylation factor-like 3	metabolic process	Biological process	-
CDC42	998	cell division cycle 42	blood coagulation	Biological process	-
STARD8	9754	StAR-related lipid transfer (START) domain containing 8	small GTPase mediated signal transduction	Biological process	-
KIF4B	285643	kinesin family member 4B	blood coagulation	Biological process	-
ATP9B	374868	ATPase, class II, type 9B	metabolic process	Biological process	-
UGDH	7358	UDP-glucose 6-dehydrogenase	electron carrier activity	Molecular function	9737970
KIF18B	146909	kinesin family member 18B	kinesin binding	Molecular function	21820309
NRG1	3084	neuregulin 1	axon	Cellular component	-
HIRA	7290	histone cell cycle regulator	chromatin modification	Biological process	-
SEMA3A	10371	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	axonogenesis involved in innervation	Biological process	-
ZNF770	54989	zinc finger protein 770	transcription from RNA polymerase II promoter	Biological process	-
RPL13	6137	ribosomal protein L13	cellular protein metabolic process	Biological process	-
PSMA7	5688	proteasome (prosome, macropain) subunit, alpha type, 7	gene expression	Biological process	-
EFEMP2	30008	EGF containing fibulin-like extracellular matrix protein 2	extracellular vesicle	Cellular component	24769233
PLA2G4B	100137049	phospholipase A2, group IVB (cytosolic)	early endosome membrane	Cellular component	-
VAV3	10451	vav 3 guanine nucleotide exchange factor	apoptotic signaling pathway	Biological process	-
NUMB	8650	numb homolog (Drosophila)	Notch signaling pathway	Biological process	-
STX3	6809	syntaxin 3	long-term synaptic potentiation	Biological process	-
CEACAM1	634	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	leukocyte migration	Biological process	-
RUFY1	80230	RUN and FYVE domain containing 1	zinc ion binding	Molecular function	-
RABL2B	11158	RAB, member of RAS oncogene family-like 2B	GTPase activity	Molecular function	10444334
RELA	5970	v-rel avian reticuloendotheliosis viral oncogene homolog A	protein complex binding	Molecular function	-
PDPN	10630	podoplanin	folic acid transport	Biological process	-
ISCA2	122961	iron-sulfur cluster assembly 2	metal ion binding	Molecular function	-
S1PR2	9294	sphingosine-1-phosphate receptor 2	lipid binding	Molecular function	10617617
MED1	5469	mediator complex subunit 1	ERK1 and ERK2 cascade	Biological process	18391015
DCX	1641	doublecortin	nervous system development	Biological process	9489699
BMP7	655	bone morphogenetic protein 7	epithelial to mesenchymal transition	Biological process	14679171
NEK5	341676	NIMA-related kinase 5	positive regulation of striated muscle cell differentiation	Biological process	-
RALGAPA2	57186	Ral GTPase activating protein, alpha subunit 2 (catalytic)	activation of GTPase activity	Biological process	-
DAZ1	1617	deleted in azoospermia 1	spermatogenesis	Biological process	-
ATP7A	538	ATPase, Cu++ transporting, alpha polypeptide	epinephrine metabolic process	Biological process	-
LSM1	27257	LSM1, U6 small nuclear RNA associated	nucleus	Cellular component	18559850
NEUROG2	63973	neurogenin 2	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
MAP3K3	4215	mitogen-activated protein kinase kinase kinase 3	positive regulation of p38MAPK cascade	Biological process	-
TMEM52B	120939	transmembrane protein 52B	molecular_function	Molecular function	-
POLD2	5425	polymerase (DNA directed), delta 2, accessory subunit	transcription-coupled nucleotide-excision repair	Biological process	-
SIX1	6495	SIX homeobox 1	regulation of epithelial cell proliferation	Biological process	-
DNAJC24	120526	DnaJ (Hsp40) homolog, subfamily C, member 24	positive regulation of ATPase activity	Biological process	22367199
AURKA	6790	aurora kinase A	mitotic spindle organization	Biological process	-
CEBPG	1054	CCAAT/enhancer binding protein (C/EBP), gamma	double-stranded DNA binding	Molecular function	-
ARR3	407	arrestin 3, retinal (X-arrestin)	regulation of protein phosphorylation	Biological process	-
APOA2	336	apolipoprotein A-II	cholesterol homeostasis	Biological process	14967812
RECQL5	9400	RecQ protein-like 5	DNA recombination	Biological process	-
FOXN4	121643	forkhead box N4	transcription, DNA-templated	Biological process	-
E2F1	1869	E2F transcription factor 1	negative regulation of DNA binding	Biological process	20176812
LOXL2	4017	lysyl oxidase-like 2	receptor-mediated endocytosis	Biological process	-
SLC16A12	387700	solute carrier family 16, member 12	lactate transmembrane transporter activity	Molecular function	-
RBMX	27316	RNA binding motif protein, X-linked	extracellular exosome	Cellular component	18445477
KIT	3815	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	protease binding	Molecular function	-
SOX9	6662	SRY (sex determining region Y)-box 9	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	20484372
FGF10	2255	fibroblast growth factor 10	keratinocyte proliferation	Biological process	-
RNF7	9616	ring finger protein 7	nucleus	Cellular component	10082581
KMT2D	8085	lysine (K)-specific methyltransferase 2D	protein binding	Molecular function	12482968
CXCL13	10563	chemokine (C-X-C motif) ligand 13	positive regulation of integrin activation	Biological process	-
COL13A1	1305	collagen, type XIII, alpha 1	extracellular matrix disassembly	Biological process	-
SLC44A3	126969	solute carrier family 44, member 3	small molecule metabolic process	Biological process	-
HPSE2	60495	heparanase 2 (inactive)	proteinaceous extracellular matrix	Cellular component	20576607
PLK2	10769	polo-like kinase 2	mitotic spindle organization	Biological process	19001868
BIRC8	112401	baculoviral IAP repeat containing 8	protease binding	Molecular function	-
DUSP4	1846	dual specificity phosphatase 4	MAP kinase tyrosine/serine/threonine phosphatase activity	Molecular function	-
HYAL1	3373	hyaluronoglucosaminidase 1	virus receptor activity	Molecular function	11296287
ELOVL3	83401	ELOVL fatty acid elongase 3	fatty acid elongation, polyunsaturated fatty acid	Biological process	20937905
TAF5	6877	TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa	transcription initiation from RNA polymerase II promoter	Biological process	-
ABCA7	10347	ATP-binding cassette, sub-family A (ABC1), member 7	negative regulation of beta-amyloid formation	Biological process	-
PHYH	5264	phytanoyl-CoA 2-hydroxylase	peroxisome	Cellular component	9326939
CRTC3	64784	CREB regulated transcription coactivator 3	viral process	Biological process	-
HDAC2	3066	histone deacetylase 2	regulation of protein kinase B signaling	Biological process	-
ABHD14B	84836	abhydrolase domain containing 14B	positive regulation of transcription from RNA polymerase II promoter	Biological process	14672934
RYR2	6262	ryanodine receptor 2 (cardiac)	extracellular exosome	Cellular component	23376485
CPQ	10404	carboxypeptidase Q	lysosome	Cellular component	-
LOXL2	4017	lysyl oxidase-like 2	scavenger receptor activity	Molecular function	-
ZNF302	55900	zinc finger protein 302	transcription, DNA-templated	Biological process	-
FGFR4	2264	fibroblast growth factor receptor 4	endosome	Cellular component	-
TAB3	257397	TGF-beta activated kinase 1/MAP3K7 binding protein 3	JNK cascade	Biological process	-
NYX	60506	nyctalopin	biological_process	Biological process	-
TOMM22	56993	translocase of outer mitochondrial membrane 22 homolog (yeast)	mitochondrial outer membrane translocase complex	Cellular component	12198123
GABRB2	2561	gamma-aminobutyric acid (GABA) A receptor, beta 2	inner ear receptor cell development	Biological process	-
DDX50	79009	DEAD (Asp-Glu-Ala-Asp) box polypeptide 50	poly(A) RNA binding	Molecular function	22658674
NTRK3	4916	neurotrophic tyrosine kinase, receptor, type 3	negative regulation of protein phosphorylation	Biological process	23027130
NXPE2	120406	neurexophilin and PC-esterase domain family, member 2	integral component of membrane	Cellular component	-
MRAP2	112609	melanocortin 2 receptor accessory protein 2	identical protein binding	Molecular function	19329486
ADGRA2	25960	adhesion G protein-coupled receptor A2	G-protein coupled receptor signaling pathway	Biological process	-
NPNT	255743	nephronectin	proteinaceous extracellular matrix	Cellular component	-
KCNK3	3777	potassium channel, two pore domain subfamily K, member 3	regulation of ion transmembrane transport	Biological process	-
CH25H	9023	cholesterol 25-hydroxylase	lipid metabolic process	Biological process	9852097
HTR2B	3357	5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled	plasma membrane	Cellular component	-
SAFB2	9667	scaffold attachment factor B2	nucleoplasm	Cellular component	-
REC114	283677	REC114 meiotic recombination protein	meiotic cell cycle	Biological process	-
KCNJ2	3759	potassium channel, inwardly rectifying subfamily J, member 2	regulation of membrane repolarization	Biological process	11371347
KHK	3795	ketohexokinase (fructokinase)	small molecule metabolic process	Biological process	-
NUP107	57122	nucleoporin 107kDa	transmembrane transport	Biological process	-
AXL	558	AXL receptor tyrosine kinase	negative regulation of neuron apoptotic process	Biological process	-
FOXP2	93986	forkhead box P2	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	-
TP53	7157	tumor protein p53	double-stranded DNA binding	Molecular function	-
SERPINB13	5275	serpin peptidase inhibitor, clade B (ovalbumin), member 13	response to UV	Biological process	9297979
MBTPS1	8720	membrane-bound transcription factor peptidase, site 1	regulation of transcription factor import into nucleus	Biological process	-
HDAC2	3066	histone deacetylase 2	protein complex	Cellular component	16217013
SEC23A	10484	Sec23 homolog A (S. cerevisiae)	protein binding	Molecular function	10075675
SLC25A38	54977	solute carrier family 25, member 38	integral component of membrane	Cellular component	-
MAP1S	55201	microtubule-associated protein 1S	actin filament binding	Molecular function	12762840
TFAP4	7023	transcription factor AP-4 (activating enhancer binding protein 4)	negative regulation of transcription, DNA-templated	Biological process	18818310
ST8SIA4	7903	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	protein glycosylation	Biological process	10766765
KLF9	687	Kruppel-like factor 9	regulation of transcription from RNA polymerase II promoter	Biological process	1356762
PIP4K2B	8396	phosphatidylinositol-5-phosphate 4-kinase, type II, beta	phosphatidylinositol biosynthetic process	Biological process	-
ADCY2	108	adenylate cyclase 2 (brain)	adenylate cyclase-modulating G-protein coupled receptor signaling pathway	Biological process	-
NEURL3	93082	neuralized E3 ubiquitin protein ligase 3	ubiquitin-protein transferase activity	Molecular function	-
CPEB1	64506	cytoplasmic polyadenylation element binding protein 1	translation repressor activity, nucleic acid binding	Molecular function	-
NKX2-1	7080	NK2 homeobox 1	forebrain development	Biological process	15494458
VAV1	7409	vav 1 guanine nucleotide exchange factor	reactive oxygen species metabolic process	Biological process	-
ADAT2	134637	adenosine deaminase, tRNA-specific 2	protein binding	Molecular function	25416956
TAOK3	51347	TAO kinase 3	ATP binding	Molecular function	-
HOXB7	3217	homeobox B7	protein binding	Molecular function	17308091
PLIN5	440503	perilipin 5	positive regulation of sequestering of triglyceride	Biological process	-
DNAJC1	64215	DnaJ (Hsp40) homolog, subfamily C, member 1	positive regulation of ATPase activity	Biological process	14668352
B4GALT1	2683	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	extracellular matrix organization	Biological process	-
SMAD6	4091	SMAD family member 6	ubiquitin protein ligase binding	Molecular function	11278251
DAG1	1605	dystroglycan 1 (dystrophin-associated glycoprotein 1)	calcium-dependent cell-matrix adhesion	Biological process	-
NFKB1	4790	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	1406630
EVX2	344191	even-skipped homeobox 2	biological_process	Biological process	-
FMNL1	752	formin-like 1	profilin binding	Molecular function	-
MLXIPL	51085	MLX interacting protein-like	positive regulation of transcription, DNA-templated	Biological process	11230181
SNX14	57231	sorting nexin 14	integral component of membrane	Cellular component	-
PSKH1	5681	protein serine kinase H1	microtubule organizing center	Cellular component	-
AMER1	139285	APC membrane recruitment protein 1	Wnt signaling pathway	Biological process	-
CRYZL1	9946	crystallin, zeta (quinone reductase)-like 1	oxidation-reduction process	Biological process	-
UQCRFS1	7386	ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1	2 iron, 2 sulfur cluster binding	Molecular function	-
NUP37	79023	nucleoporin 37kDa	mitotic cell cycle	Biological process	-
ENPEP	2028	glutamyl aminopeptidase (aminopeptidase A)	brush border	Cellular component	-
TAAR2	9287	trace amine associated receptor 2	sensory perception of chemical stimulus	Biological process	-
SDC1	6382	syndecan 1	myoblast development	Biological process	-
CYBA	1535	cytochrome b-245, alpha polypeptide	superoxide-generating NADPH oxidase activity	Molecular function	1763037
PGF	5228	placental growth factor	response to hypoxia	Biological process	-
CSN3	1448	casein kappa	molecular_function	Molecular function	-
PPAT	5471	phosphoribosyl pyrophosphate amidotransferase	metal ion binding	Molecular function	-
FKBP1A	2280	FK506 binding protein 1A, 12kDa	peptidyl-prolyl cis-trans isomerase activity	Molecular function	11322937
HLX	3142	H2.0-like homeobox	negative regulation of T-helper 2 cell differentiation	Biological process	-
FERMT3	83706	fermitin family member 3	membrane	Cellular component	19946888
SCAMP2	10066	secretory carrier membrane protein 2	Golgi apparatus	Cellular component	-
LOXL2	4017	lysyl oxidase-like 2	chromatin binding	Molecular function	22483618
TIGIT	201633	T cell immunoreceptor with Ig and ITIM domains	positive regulation of interleukin-10 production	Biological process	19011627
PIH1D3	139212	PIH1 domain containing 3	chaperone binding	Molecular function	-
NTRK1	4914	neurotrophic tyrosine kinase, receptor, type 1	receptor complex	Cellular component	23382219
PCDHA11	56138	protocadherin alpha 11	nervous system development	Biological process	10380929
LRP1	4035	low density lipoprotein receptor-related protein 1	coated pit	Cellular component	-
TFDP2	7029	transcription factor Dp-2 (E2F dimerization partner 2)	protein binding	Molecular function	16189514
FGD6	55785	FYVE, RhoGEF and PH domain containing 6	regulation of GTPase activity	Biological process	-
BOP1	23246	block of proliferation 1	ribosome biogenesis	Biological process	16043514
RICTOR	253260	RPTOR independent companion of MTOR, complex 2	phosphatidylinositol-mediated signaling	Biological process	-
FTMT	94033	ferritin mitochondrial	ferroxidase activity	Molecular function	-
COL18A1	80781	collagen, type XVIII, alpha 1	structural molecule activity	Molecular function	-
NDUFS4	4724	NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)	positive regulation of fibroblast proliferation	Biological process	16478720
RAPGEF6	51735	Rap guanine nucleotide exchange factor (GEF) 6	plasma membrane	Cellular component	11524421
SHPRH	257218	SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase	ubiquitin-protein transferase activity	Molecular function	17108083
BAX	581	BCL2-associated X protein	homeostasis of number of cells within a tissue	Biological process	-
ARPC4	10093	actin related protein 2/3 complex, subunit 4, 20kDa	extracellular exosome	Cellular component	19056867
MYD88	4615	myeloid differentiation primary response 88	cytosol	Cellular component	-
SLC25A10	1468	solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10	integral component of membrane	Cellular component	-
CDC42	998	cell division cycle 42	Fc-gamma receptor signaling pathway involved in phagocytosis	Biological process	-
PRKCD	5580	protein kinase C, delta	programmed cell death	Biological process	-
AMD1	262	adenosylmethionine decarboxylase 1	cytosol	Cellular component	-
MLLT1	4298	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1	regulation of transcription, DNA-templated	Biological process	-
TMEM56	148534	transmembrane protein 56	cellular_component	Cellular component	-
CYS1	192668	cystin 1	membrane raft	Cellular component	-
SDC1	6382	syndecan 1	protein binding	Molecular function	15292202
MAT2A	4144	methionine adenosyltransferase II, alpha	methionine adenosyltransferase activity	Molecular function	10644686
RPS4Y2	140032	ribosomal protein S4, Y-linked 2	structural constituent of ribosome	Molecular function	-
DAZ2	57055	deleted in azoospermia 2	multicellular organismal development	Biological process	-
APPL1	26060	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	protein binding	Molecular function	10490823
FAXDC2	10826	fatty acid hydroxylase domain containing 2	fatty acid biosynthetic process	Biological process	-
LDLR	3949	low density lipoprotein receptor	clathrin-coated endocytic vesicle membrane	Cellular component	-
GNB2L1	10399	guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1	positive regulation of gastrulation	Biological process	-
BIRC6	57448	baculoviral IAP repeat containing 6	mitotic nuclear division	Biological process	-
LITAF	9516	lipopolysaccharide-induced TNF factor	aging	Biological process	-
GGT3P	2679	gamma-glutamyltransferase 3 pseudogene	proteolysis	Biological process	-
THBS1	7057	thrombospondin 1	positive regulation of endothelial cell migration	Biological process	18555217
TGFBR1	7046	transforming growth factor, beta receptor 1	in utero embryonic development	Biological process	-
MEN1	4221	multiple endocrine neoplasia I	Y-form DNA binding	Molecular function	15331604
DAPP1	27071	dual adaptor of phosphotyrosine and 3-phosphoinositides	phosphatidylinositol-3,4-bisphosphate binding	Molecular function	17823121
DNM1L	10059	dynamin 1-like	peroxisome	Cellular component	23921378
USP13	8975	ubiquitin specific peptidase 13 (isopeptidase T-3)	zinc ion binding	Molecular function	-
MED1	5469	mediator complex subunit 1	cellular lipid metabolic process	Biological process	-
ESRRA	2101	estrogen-related receptor alpha	intracellular receptor signaling pathway	Biological process	9286700
SMAD3	4088	SMAD family member 3	negative regulation of inflammatory response	Biological process	-
RDX	5962	radixin	apical protein localization	Biological process	-
AURKAIP1	54998	aurora kinase A interacting protein 1	organelle organization	Biological process	-
ZDHHC21	340481	zinc finger, DHHC-type containing 21	palmitoyltransferase activity	Molecular function	23034182
PRR13	54458	proline rich 13	protein binding	Molecular function	16189514
SOX9	6662	SRY (sex determining region Y)-box 9	endocrine pancreas development	Biological process	-
STAC2	342667	SH3 and cysteine rich domain 2	metal ion binding	Molecular function	-
NUP93	9688	nucleoporin 93kDa	structural constituent of nuclear pore	Molecular function	15229283
NDUFA9	4704	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa	nucleus	Cellular component	21630459
RPS25	6230	ribosomal protein S25	translation	Biological process	-
JAK1	3716	Janus kinase 1	protein tyrosine kinase activity	Molecular function	-
H6PD	9563	hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)	glucose 1-dehydrogenase [NAD(P)] activity	Molecular function	-
KCND1	3750	potassium channel, voltage gated Shal related subfamily D, member 1	potassium ion transmembrane transport	Biological process	-
GABRG3	2567	gamma-aminobutyric acid (GABA) A receptor, gamma 3	response to drug	Biological process	-
SORD	6652	sorbitol dehydrogenase	extracellular exosome	Cellular component	19056867
HLA-C	3107	major histocompatibility complex, class I, C	extracellular region	Cellular component	-
S100A13	6284	S100 calcium binding protein A13	lipid binding	Molecular function	-
CLN5	1203	ceroid-lipofuscinosis, neuronal 5	protein catabolic process	Biological process	10740217
SMAD2	4087	SMAD family member 2	double-stranded DNA binding	Molecular function	-
DRD2	1813	dopamine receptor D2	positive regulation of multicellular organism growth	Biological process	-
PIK3CB	5291	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta	chemotaxis	Biological process	10570282
PHF5A	84844	PHD finger protein 5A	mRNA splicing, via spliceosome	Biological process	-
GLI4	2738	GLI family zinc finger 4	sequence-specific DNA binding transcription factor activity	Molecular function	-
APBA3	9546	amyloid beta (A4) precursor protein-binding, family A, member 3	protein binding	Molecular function	10049767
HAP1	9001	huntingtin-associated protein 1	synaptic vesicle	Cellular component	-
RNASE3	6037	ribonuclease, RNase A family, 3	antibacterial humoral response	Biological process	12860195
APOBEC3D	140564	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	Biological process	21835787
HSP90AB1	3326	heat shock protein 90kDa alpha (cytosolic), class B member 1	virion attachment to host cell	Biological process	24098578
SFT2D1	113402	SFT2 domain containing 1	protein transport	Biological process	-
PACSIN2	11252	protein kinase C and casein kinase substrate in neurons 2	early endosome	Cellular component	-
NRG1	3084	neuregulin 1	positive regulation of cardiac muscle cell proliferation	Biological process	9553078
CCT3	7203	chaperonin containing TCP1, subunit 3 (gamma)	zona pellucida receptor complex	Cellular component	-
NTRK1	4914	neurotrophic tyrosine kinase, receptor, type 1	Sertoli cell development	Biological process	-
DTX1	1840	deltex 1, E3 ubiquitin ligase	transcription coactivator activity	Molecular function	9590294
KIRREL3	84623	kin of IRRE like 3 (Drosophila)	extracellular region	Cellular component	-
ZFP37	7539	ZFP37 zinc finger protein	transcription, DNA-templated	Biological process	-
CLK2	1196	CDC-like kinase 2	protein autophosphorylation	Biological process	-
EPHB3	2049	EPH receptor B3	positive regulation of synapse assembly	Biological process	-
CETP	1071	cholesteryl ester transfer protein, plasma	reverse cholesterol transport	Biological process	7583561
ZNF638	27332	zinc finger protein 638	nucleoplasm	Cellular component	-
MYO5B	4645	myosin VB	metabolic process	Biological process	-
MAL2	114569	mal, T-cell differentiation protein 2 (gene/pseudogene)	extracellular exosome	Cellular component	19056867
KRAS	3845	Kirsten rat sarcoma viral oncogene homolog	blood coagulation	Biological process	-
SLC2A10	81031	solute carrier family 2 (facilitated glucose transporter), member 10	glucose import	Biological process	-
LTK	4058	leukocyte receptor tyrosine kinase	transmembrane receptor protein tyrosine kinase signaling pathway	Biological process	-
FASTKD3	79072	FAST kinase domains 3	protein kinase activity	Molecular function	-
ERBB2	2064	erb-b2 receptor tyrosine kinase 2	protein phosphorylation	Biological process	10851066
REPIN1	29803	replication initiator 1	DNA replication	Biological process	-
UBE2J2	118424	ubiquitin-conjugating enzyme E2, J2	positive regulation of protein targeting to mitochondrion	Biological process	24270810
SYNDIG1	79953	synapse differentiation inducing 1	early endosome membrane	Cellular component	-
NGF	4803	nerve growth factor (beta polypeptide)	metalloendopeptidase inhibitor activity	Molecular function	20164177
IVNS1ABP	10625	influenza virus NS1A binding protein	response to virus	Biological process	9696811
GRIN2B	2904	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	learning or memory	Biological process	10485705
WNT9A	7483	wingless-type MMTV integration site family, member 9A	embryonic skeletal system morphogenesis	Biological process	-
RHO	6010	rhodopsin	rough endoplasmic reticulum membrane	Cellular component	-
MTFR1	9650	mitochondrial fission regulator 1	aerobic respiration	Biological process	-
SRY	6736	sex determining region Y	nucleoplasm	Cellular component	-
BTN2A2	10385	butyrophilin, subfamily 2, member A2	integral component of membrane	Cellular component	-
SNCA	6622	synuclein, alpha (non A4 component of amyloid precursor)	phosphoprotein binding	Molecular function	21127069
PPM1G	5496	protein phosphatase, Mg2+/Mn2+ dependent, 1G	protein serine/threonine phosphatase activity	Molecular function	20801214
CALCRL	10203	calcitonin receptor-like	calcitonin receptor activity	Molecular function	-
IL6	3569	interleukin 6	positive regulation of T cell proliferation	Biological process	3130269
PCBP3	54039	poly(rC) binding protein 3	extracellular exosome	Cellular component	23533145
PCK2	5106	phosphoenolpyruvate carboxykinase 2 (mitochondrial)	GTP binding	Molecular function	-
CYP46A1	10858	cytochrome P450, family 46, subfamily A, polypeptide 1	endoplasmic reticulum membrane	Cellular component	-
SRI	6717	sorcin	protein heterodimerization activity	Molecular function	12804766
RXRG	6258	retinoid X receptor, gamma	protein homotetramerization	Biological process	-
CD58	965	CD58 molecule	cell surface	Cellular component	15345303
KHSRP	8570	KH-type splicing regulatory protein	RNA splicing	Biological process	10911989
PLCB1	23236	phospholipase C, beta 1 (phosphoinositide-specific)	interleukin-1-mediated signaling pathway	Biological process	8872139
CALM3	808	calmodulin 3 (phosphorylase kinase, delta)	spindle microtubule	Cellular component	16760425
NFXL1	152518	nuclear transcription factor, X-box binding-like 1	nucleus	Cellular component	-
APBB1	322	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	regulation of transcription, DNA-templated	Biological process	-
GFRAL	389400	GDNF family receptor alpha like	negative regulation of neuron apoptotic process	Biological process	-
PURA	5813	purine-rich element binding protein A	DNA unwinding involved in DNA replication	Biological process	15777841
ZBTB18	10472	zinc finger and BTB domain containing 18	nucleus	Cellular component	9013868
MFSD2A	84879	major facilitator superfamily domain containing 2A	cytoplasm	Cellular component	-
OR1J2	26740	olfactory receptor, family 1, subfamily J, member 2	detection of chemical stimulus involved in sensory perception	Biological process	-
FKBP15	23307	FK506 binding protein 15, 133kDa	axon	Cellular component	-
GLI2	2736	GLI family zinc finger 2	tube development	Biological process	-
PDGFRA	5156	platelet-derived growth factor receptor, alpha polypeptide	retina vasculature development in camera-type eye	Biological process	-
ARHGAP4	393	Rho GTPase activating protein 4	GTPase activator activity	Molecular function	-
ZNF677	342926	zinc finger protein 677	sequence-specific DNA binding transcription factor activity	Molecular function	-
CHP1	11261	calcineurin-like EF-hand protein 1	hyaluronan metabolic process	Biological process	-
NDOR1	27158	NADPH dependent diflavin oxidoreductase 1	intermediate filament cytoskeleton	Cellular component	-
LY6H	4062	lymphocyte antigen 6 complex, locus H	organ morphogenesis	Biological process	9799603
CAPN3	825	calpain 3, (p94)	structural constituent of muscle	Molecular function	-
TRAF7	84231	TNF receptor-associated factor 7, E3 ubiquitin protein ligase	apoptotic process	Biological process	15001576
KIR2DL4	3805	killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4	cellular defense response	Biological process	8946682
SRRM1	10250	serine/arginine repetitive matrix 1	nucleoplasm	Cellular component	-
H1FNT	341567	H1 histone family, member N, testis-specific	DNA binding	Molecular function	-
AGPAT5	55326	1-acylglycerol-3-phosphate O-acyltransferase 5	integral component of membrane	Cellular component	-
CCND3	896	cyclin D3	cell division	Biological process	-
DAB1	1600	Dab, reelin signal transducer, homolog 1 (Drosophila)	postsynaptic density	Cellular component	-
ROPN1B	152015	rhophilin associated tail protein 1B	Rho protein signal transduction	Biological process	11278869
NCOA3	8202	nuclear receptor coactivator 3	protein dimerization activity	Molecular function	-
TRIM32	22954	tripartite motif containing 32	ubiquitin protein ligase activity	Molecular function	16816390
DOC2B	8447	double C2-like domains, beta	calcium ion binding	Molecular function	-
EGFR	1956	epidermal growth factor receptor	positive regulation of phosphorylation	Biological process	15082764
PSMA8	143471	proteasome (prosome, macropain) subunit, alpha type, 8	negative regulation of canonical Wnt signaling pathway	Biological process	-
ZRANB2	9406	zinc finger, RAN-binding domain containing 2	RNA splicing	Biological process	-
TRMU	55687	tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase	tRNA methylation	Biological process	-
GALNT3	2591	polypeptide N-acetylgalactosaminyltransferase 3	carbohydrate binding	Molecular function	-
WDR62	284403	WD repeat domain 62	neurogenesis	Biological process	20890278
PRR5L	79899	proline rich 5 like	TORC2 signaling	Biological process	22609986
LRPPRC	10128	leucine-rich pentatricopeptide repeat containing	microtubule binding	Molecular function	12762840
GPS2	2874	G protein pathway suppressor 2	negative regulation of GTPase activity	Biological process	8943324
CD109	135228	CD109 molecule	anchored component of membrane	Cellular component	-
BUB1	699	BUB1 mitotic checkpoint serine/threonine kinase	apoptotic process	Biological process	-
MSH5	4439	mutS homolog 5	ATP binding	Molecular function	-
IL7	3574	interleukin 7	protein binding	Molecular function	8266077
PTPN1	5770	protein tyrosine phosphatase, non-receptor type 1	negative regulation of insulin receptor signaling pathway	Biological process	11742412
ERCC2	2068	excision repair cross-complementation group 2	spinal cord development	Biological process	-
TMED5	50999	transmembrane emp24 protein transport domain containing 5	Golgi ribbon formation	Biological process	19948005
ABCG1	9619	ATP-binding cassette, sub-family G (WHITE), member 1	Golgi apparatus	Cellular component	-
MMP15	4324	matrix metallopeptidase 15 (membrane-inserted)	collagen catabolic process	Biological process	-
PPIF	10105	peptidylprolyl isomerase F	response to ischemia	Biological process	-
JUN	3725	jun proto-oncogene	RNA polymerase II activating transcription factor binding	Molecular function	19861239
FRS2	10818	fibroblast growth factor receptor substrate 2	endosome	Cellular component	-
UBE2A	7319	ubiquitin-conjugating enzyme E2A	positive regulation of cell proliferation	Biological process	11953320
TREM1	54210	triggering receptor expressed on myeloid cells 1	scaffold protein binding	Molecular function	11602640
KCNE1	3753	potassium channel, voltage gated subfamily E regulatory beta subunit 1	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	Molecular function	10400998
SLC12A2	6558	solute carrier family 12 (sodium/potassium/chloride transporter), member 2	extracellular vesicle	Cellular component	24769233
PCGF6	84108	polycomb group ring finger 6	RNA polymerase II regulatory region sequence-specific DNA binding	Molecular function	-
CD74	972	CD74 molecule, major histocompatibility complex, class II invariant chain	immunoglobulin mediated immune response	Biological process	-
PAPOLB	56903	poly(A) polymerase beta (testis specific)	nucleus	Cellular component	-
GYS1	2997	glycogen synthase 1 (muscle)	carbohydrate metabolic process	Biological process	-
PNPLA3	80339	patatin-like phospholipase domain containing 3	small molecule metabolic process	Biological process	-
ECE2	9718	endothelin converting enzyme 2	heart development	Biological process	-
RECQL4	9401	RecQ protein-like 4	ATP binding	Molecular function	19177149
AMIGO2	347902	adhesion molecule with Ig-like domain 2	homophilic cell adhesion via plasma membrane adhesion molecules	Biological process	12629050
TP63	8626	tumor protein p63	protein homotetramerization	Biological process	10373484
SRP72	6731	signal recognition particle 72kDa	signal recognition particle, endoplasmic reticulum targeting	Cellular component	18089836
FBXL7	23194	F-box and leucine-rich repeat protein 7	ubiquitin ligase complex	Cellular component	10531035
UNKL	64718	unkempt family zinc finger-like	zinc ion binding	Molecular function	-
STAT6	6778	signal transducer and activator of transcription 6, interleukin-4 induced	mammary gland morphogenesis	Biological process	-
THY1	7070	Thy-1 cell surface antigen	extracellular exosome	Cellular component	19056867
E4F1	1877	E4F transcription factor 1	regulation of mitotic cell cycle, embryonic	Biological process	-
UVSSA	57654	UV-stimulated scaffold protein A	response to UV	Biological process	22466610
MUC7	4589	mucin 7, secreted	protein O-linked glycosylation	Biological process	-
MGST2	4258	microsomal glutathione S-transferase 2	glutathione derivative biosynthetic process	Biological process	-
NBL1	4681	neuroblastoma 1, DAN family BMP antagonist	negative regulation of monocyte chemotaxis	Biological process	-
BID	637	BH3 interacting domain death agonist	glial cell apoptotic process	Biological process	-
LY96	23643	lymphocyte antigen 96	innate immune response	Biological process	-
PRKRIR	5612	protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)	DNA binding	Molecular function	-
MEX3D	399664	mex-3 RNA binding family member D	mRNA destabilization	Biological process	14769789
POLR3K	51728	polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa	zinc ion binding	Molecular function	-
GPD1L	23171	glycerol-3-phosphate dehydrogenase 1-like	glycerol-3-phosphate dehydrogenase complex	Cellular component	-
TAC1	6863	tachykinin, precursor 1	positive regulation of synaptic transmission, cholinergic	Biological process	-
EDEM2	55741	ER degradation enhancer, mannosidase alpha-like 2	response to unfolded protein	Biological process	-
CLN6	54982	ceroid-lipofuscinosis, neuronal 6, late infantile, variant	protein binding	Molecular function	19235893
TFAM	7019	transcription factor A, mitochondrial	poly(A) RNA binding	Molecular function	22658674
DNA2	1763	DNA replication helicase/nuclease 2	site-specific endodeoxyribonuclease activity, specific for altered base	Molecular function	18995831
TXN2	25828	thioredoxin 2	protein disulfide oxidoreductase activity	Molecular function	-
ATF4	468	activating transcription factor 4	endoplasmic reticulum unfolded protein response	Biological process	-
SEMA6B	10501	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B	semaphorin receptor binding	Molecular function	-
DAPK3	1613	death-associated protein kinase 3	protein phosphorylation	Biological process	10356987
CBX5	23468	chromobox homolog 5	chromocenter	Cellular component	-
TDRD9	122402	tudor domain containing 9	cytoplasm	Cellular component	-
MCM8	84515	minichromosome maintenance complex component 8	mitotic cell cycle	Biological process	-
TMEM115	11070	transmembrane protein 115	negative regulation of cell proliferation	Biological process	17973242
MUC5AC	4586	mucin 5AC, oligomeric mucus/gel-forming	cytoplasm	Cellular component	25591774
MAPK1	5594	mitogen-activated protein kinase 1	neurotrophin TRK receptor signaling pathway	Biological process	-
C5AR1	728	complement component 5a receptor 1	immune response	Biological process	9590258
SLC8A1	6546	solute carrier family 8 (sodium/calcium exchanger), member 1	regulation of cardiac muscle contraction by calcium ion signaling	Biological process	23224879
CCNT1	904	cyclin T1	protein binding	Molecular function	12944466
SMARCD3	6604	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3	cytoplasm	Cellular component	17363140
SOD1	6647	superoxide dismutase 1, soluble	regulation of GTPase activity	Biological process	18219391
TBC1D30	23329	TBC1 domain family, member 30	GTPase activator activity	Molecular function	17646400
THBS1	7057	thrombospondin 1	positive regulation of phosphorylation	Biological process	17413041
MBD3L1	85509	methyl-CpG binding domain protein 3-like 1	nucleoplasm	Cellular component	-
CNOT8	9337	CCR4-NOT transcription complex, subunit 8	poly(A)-specific ribonuclease activity	Molecular function	15769875
LGR4	55366	leucine-rich repeat containing G protein-coupled receptor 4	negative regulation of toll-like receptor signaling pathway	Biological process	-
ZNF181	339318	zinc finger protein 181	transcription, DNA-templated	Biological process	-
DGKZ	8525	diacylglycerol kinase, zeta	intracellular signal transduction	Biological process	-
CCDC86	79080	coiled-coil domain containing 86	protein binding	Molecular function	15607035
MTFR2	113115	mitochondrial fission regulator 2	mitochondrion	Cellular component	-
XPO1	7514	exportin 1	nucleoplasm	Cellular component	-
FAIM2	23017	Fas apoptotic inhibitory molecule 2	postsynaptic membrane	Cellular component	-
LAMB1	3912	laminin, beta 1	positive regulation of cell migration	Biological process	16289578
MYC	4609	v-myc avian myelocytomatosis viral oncogene homolog	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	10723141
AOC3	8639	amine oxidase, copper containing 3	protein homodimerization activity	Molecular function	9653080
DIAPH3	81624	diaphanous-related formin 3	small GTPase mediated signal transduction	Biological process	-
ADH7	131	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	small molecule metabolic process	Biological process	-
PTPRJ	5795	protein tyrosine phosphatase, receptor type, J	negative regulation of T cell receptor signaling pathway	Biological process	11259588
PSMC5	5705	proteasome (prosome, macropain) 26S subunit, ATPase, 5	positive regulation of transcription, DNA-templated	Biological process	7870181
CCM2	83605	cerebral cavernous malformation 2	pericardium development	Biological process	-
ATP5F1	515	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1	cellular metabolic process	Biological process	-
MRPS34	65993	mitochondrial ribosomal protein S34	mitochondrion	Cellular component	-
TCF21	6943	transcription factor 21	morphogenesis of a branching structure	Biological process	-
ETFB	2109	electron-transfer-flavoprotein, beta polypeptide	mitochondrion	Cellular component	-
CBFB	865	core-binding factor, beta subunit	membrane	Cellular component	19946888
ANKRD2	26287	ankyrin repeat domain 2 (stretch responsive muscle)	I band	Cellular component	-
COL14A1	7373	collagen, type XIV, alpha 1	ventricular cardiac muscle tissue development	Biological process	-
SURF4	6836	surfeit 4	positive regulation of organelle organization	Biological process	18287528
KCTD14	65987	potassium channel tetramerization domain containing 14	protein homooligomerization	Biological process	-
GPR34	2857	G protein-coupled receptor 34	G-protein coupled purinergic nucleotide receptor activity	Molecular function	-
CDK9	1025	cyclin-dependent kinase 9	DNA binding	Molecular function	16109376
EPHB6	2051	EPH receptor B6	plasma membrane	Cellular component	-
ZNF235	9310	zinc finger protein 235	regulation of transcription, DNA-templated	Biological process	-
NAA60	79903	N(alpha)-acetyltransferase 60, NatF catalytic subunit	nucleosome assembly	Biological process	21981917
PDX1	3651	pancreatic and duodenal homeobox 1	liver development	Biological process	-
SHQ1	55164	SHQ1, H/ACA ribonucleoprotein assembly factor	positive regulation of apoptotic process	Biological process	20663920
PRDX4	10549	peroxiredoxin 4	male gonad development	Biological process	-
PDGFRA	5156	platelet-derived growth factor receptor, alpha polypeptide	nucleus	Cellular component	-
WIZ	58525	widely interspaced zinc finger motifs	positive regulation of nuclear cell cycle DNA replication	Biological process	23545495
TMED10	10972	transmembrane emp24-like trafficking protein 10 (yeast)	kidney development	Biological process	-
PRKACA	5566	protein kinase, cAMP-dependent, catalytic, alpha	regulation of bicellular tight junction assembly	Biological process	15905176
NHP2L1	4809	NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)	ribosome biogenesis	Biological process	-
ACADSB	36	acyl-CoA dehydrogenase, short/branched chain	oxidation-reduction process	Biological process	-
APOA5	116519	apolipoprotein A-V	lipase activator activity	Molecular function	15178420
BCAS2	10286	breast carcinoma amplified sequence 2	RNA splicing	Biological process	9731529
PBX1	5087	pre-B-cell leukemia homeobox 1	cytoplasm	Cellular component	18973687
APOA5	116519	apolipoprotein A-V	acylglycerol homeostasis	Biological process	15178420
LGALS14	56891	lectin, galactoside-binding, soluble, 14	apoptotic process	Biological process	-
MAGOH	4116	mago-nashi homolog, proliferation-associated (Drosophila)	regulation of translation	Biological process	-
KCNE2	9992	potassium channel, voltage gated subfamily E regulatory beta subunit 2	inward rectifier potassium channel activity	Molecular function	10219239
UBA2	10054	ubiquitin-like modifier activating enzyme 2	transcription factor binding	Molecular function	-
RASD2	23551	RASD family, member 2	ubiquitin conjugating enzyme binding	Molecular function	-
SOX3	6658	SRY (sex determining region Y)-box 3	RNA polymerase II core promoter sequence-specific DNA binding	Molecular function	-
ZNF224	7767	zinc finger protein 224	nucleoplasm	Cellular component	-
ATAD1	84896	ATPase family, AAA domain containing 1	memory	Biological process	-
CD14	929	CD14 molecule	extracellular exosome	Cellular component	19056867
EXD3	54932	exonuclease 3'-5' domain containing 3	nucleus	Cellular component	-
ZMYM6NB	100506144	ZMYM6 neighbor	integral component of membrane	Cellular component	-
LMO7	4008	LIM domain 7	protein ubiquitination	Biological process	10531035
NEK4	6787	NIMA-related kinase 4	regulation of cellular senescence	Biological process	22851694
TOR1A	1861	torsin family 1, member A (torsin A)	protein homooligomerization	Biological process	20015956
ATOH7	220202	atonal homolog 7 (Drosophila)	protein dimerization activity	Molecular function	-
PSEN1	5663	presenilin 1	beta-catenin binding	Molecular function	11104755
AHR	196	aryl hydrocarbon receptor	regulation of transcription from RNA polymerase II promoter	Biological process	15681594
CRHBP	1393	corticotropin releasing hormone binding protein	multivesicular body	Cellular component	-
DOHH	83475	deoxyhypusine hydroxylase/monooxygenase	oxidation-reduction process	Biological process	-
CTSB	1508	cathepsin B	nucleolus	Cellular component	-
RPS12	6206	ribosomal protein S12	viral transcription	Biological process	-
KLRG1	10219	killer cell lectin-like receptor subfamily G, member 1	protein binding	Molecular function	25416956
BANF2	140836	barrier to autointegration factor 2	nucleus	Cellular component	21630459
PDK3	5165	pyruvate dehydrogenase kinase, isozyme 3	regulation of acetyl-CoA biosynthetic process from pyruvate	Biological process	-
NLRP3	114548	NLR family, pyrin domain containing 3	NLRP3 inflammasome complex	Cellular component	15030775
IL13	3596	interleukin 13	positive regulation of connective tissue growth factor production	Biological process	-
STRA8	346673	stimulated by retinoic acid 8	DNA replication	Biological process	-
ZBTB18	10472	zinc finger and BTB domain containing 18	regulation of cell division	Biological process	-
SLC34A1	6569	solute carrier family 34 (type II sodium/phosphate cotransporter), member 1	protein complex binding	Molecular function	-
ADAMTS7	11173	ADAM metallopeptidase with thrombospondin type 1 motif, 7	cellular protein metabolic process	Biological process	-
MVB12A	93343	multivesicular body subunit 12A	ubiquitin binding	Molecular function	20654576
NLGN4X	57502	neuroligin 4, X-linked	synapse organization	Biological process	11368788
PLCB3	5331	phospholipase C, beta 3 (phosphatidylinositol-specific)	intracellular signal transduction	Biological process	-
BCL10	8915	B-cell CLL/lymphoma 10	positive regulation of interleukin-8 biosynthetic process	Biological process	17095757
STIM2	57620	stromal interaction molecule 2	calcium ion binding	Molecular function	18166150
PKD2L1	9033	polycystic kidney disease 2-like 1	protein binding	Molecular function	12525172
DNA2	1763	DNA replication helicase/nuclease 2	mitochondrial DNA repair	Biological process	19487465
SHISA5	51246	shisa family member 5	WW domain binding	Molecular function	15064722
TRPV5	56302	transient receptor potential cation channel, subfamily V, member 5	integral component of plasma membrane	Cellular component	15489237
CHRM2	1129	cholinergic receptor, muscarinic 2	integral component of plasma membrane	Cellular component	24256733
ONECUT1	3175	one cut homeobox 1	B cell differentiation	Biological process	-
CDX2	1045	caudal type homeobox 2	establishment or maintenance of epithelial cell apical/basal polarity	Biological process	-
FEZ1	9638	fasciculation and elongation protein zeta 1 (zygin I)	transport	Biological process	-
MMAA	166785	methylmalonic aciduria (cobalamin deficiency) cblA type	cobalamin metabolic process	Biological process	-
TLR9	54106	toll-like receptor 9	positive regulation of JUN kinase activity	Biological process	17128265
APOE	348	apolipoprotein E	heparin binding	Molecular function	2745454
PALM2	114299	paralemmin 2	regulation of cell shape	Biological process	-
DLG5	9231	discs, large homolog 5 (Drosophila)	regulation of apoptotic process	Biological process	-
FOXB1	27023	forkhead box B1	transcription from RNA polymerase II promoter	Biological process	-
ZNF597	146434	zinc finger protein 597	regulation of transcription, DNA-templated	Biological process	-
NONO	4841	non-POU domain containing, octamer-binding	nucleus	Cellular component	-
OVOS	408186	ovostatin	negative regulation of endopeptidase activity	Biological process	-
NRXN1	9378	neurexin 1	neuronal signal transduction	Biological process	15797875
MPP7	143098	membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)	positive regulation of protein complex assembly	Biological process	14719143
MRPL27	51264	mitochondrial ribosomal protein L27	mitochondrial inner membrane	Cellular component	-
ITPKC	80271	inositol-trisphosphate 3-kinase C	activation of mitophagy in response to mitochondrial depolarization	Biological process	22020285
MT3	4504	metallothionein 3	protein import into nucleus, translocation	Biological process	18554677
NELL1	4745	NEL-like 1 (chicken)	extracellular region	Cellular component	-
ARL8B	55207	ADP-ribosylation factor-like 8B	alpha-tubulin binding	Molecular function	15331635
AGO1	26523	argonaute RISC catalytic component 1	RISC-loading complex	Cellular component	19966796
IFT140	9742	intraflagellar transport 140	cilium assembly	Biological process	-
STC1	6781	stanniocalcin 1	apical plasma membrane	Cellular component	-
VTI1B	10490	vesicle transport through interaction with t-SNAREs 1B	protein targeting to vacuole	Biological process	-
GNG3	2785	guanine nucleotide binding protein (G protein), gamma 3	plasma membrane	Cellular component	-
KDELR3	11015	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3	IRE1-mediated unfolded protein response	Biological process	-
TFAP2D	83741	transcription factor AP-2 delta (activating enhancer binding protein 2 delta)	sequence-specific DNA binding RNA polymerase II transcription factor activity	Molecular function	-
RPS18	6222	ribosomal protein S18	cytosolic small ribosomal subunit	Cellular component	15883184
DUSP4	1846	dual specificity phosphatase 4	toll-like receptor 5 signaling pathway	Biological process	-
OVOL3	728361	ovo-like zinc finger 3	regulation of transcription from RNA polymerase II promoter	Biological process	-
ATP1A3	478	ATPase, Na+/K+ transporting, alpha 3 polypeptide	sodium:potassium-exchanging ATPase activity	Molecular function	15260953
MAPK8IP1	9479	mitogen-activated protein kinase 8 interacting protein 1	mitochondrial membrane	Cellular component	-
LRRC8A	56262	leucine rich repeat containing 8 family, member A	cell volume homeostasis	Biological process	24725410
CBL	867	Cbl proto-oncogene, E3 ubiquitin protein ligase	protein binding	Molecular function	10068674
ECE1	1889	endothelin converting enzyme 1	pharyngeal system development	Biological process	-
RALB	5899	v-ral simian leukemia viral oncogene homolog B	positive regulation of protein serine/threonine kinase activity	Biological process	24056301
FBXW8	26259	F-box and WD repeat domain containing 8	protein ubiquitination	Biological process	-
ZFAND2B	130617	zinc finger, AN1-type domain 2B	protein binding	Molecular function	16189514
GDF2	2658	growth differentiation factor 2	blood vessel morphogenesis	Biological process	20406889
APC	324	adenomatous polyposis coli	bicellular tight junction	Cellular component	18502210
TAC1	6863	tachykinin, precursor 1	associative learning	Biological process	-
FOXF1	2294	forkhead box F1	positive regulation of cell-substrate adhesion	Biological process	-
OR52E4	390081	olfactory receptor, family 52, subfamily E, member 4	integral component of membrane	Cellular component	-
COQ6	51004	coenzyme Q6 monooxygenase	mitochondrial inner membrane	Cellular component	-
TMEM120B	144404	transmembrane protein 120B	cellular_component	Cellular component	-
NDNF	79625	neuron-derived neurotrophic factor	cell growth	Biological process	20969804
ZNF138	7697	zinc finger protein 138	transcription, DNA-templated	Biological process	-
RPS18	6222	ribosomal protein S18	rRNA binding	Molecular function	-
PRL	5617	prolactin	cell surface receptor signaling pathway	Biological process	10854700
PAX6	5080	paired box 6	eye development	Biological process	10747901
CHRNB1	1140	cholinergic receptor, nicotinic, beta 1 (muscle)	postsynaptic membrane organization	Biological process	8651643
VAPA	9218	VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa	FFAT motif binding	Molecular function	18713837
KLHL5	51088	kelch-like family member 5	actin binding	Molecular function	-
USP8	9101	ubiquitin specific peptidase 8	early endosome	Cellular component	16520378
HIST1H4K	8362	histone cluster 1, H4k	nuclear chromosome	Cellular component	14718166
NEK2	4751	NIMA-related kinase 2	cell division	Biological process	-
PRKACB	5567	protein kinase, cAMP-dependent, catalytic, beta	plasma membrane	Cellular component	-
WWC2	80014	WW and C2 domain containing 2	negative regulation of organ growth	Biological process	24682284
GPCPD1	56261	glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)	starch binding	Molecular function	-
MEN1	4221	multiple endocrine neoplasia I	leukocyte homeostasis	Biological process	-
GGT2	728441	gamma-glutamyltransferase 2	small molecule metabolic process	Biological process	-
QRFP	347148	pyroglutamylated RFamide peptide	neuropeptide hormone activity	Molecular function	14657341
SLC24A1	9187	solute carrier family 24 (sodium/potassium/calcium exchanger), member 1	phototransduction, visible light	Biological process	-
CTSB	1508	cathepsin B	extracellular matrix disassembly	Biological process	-
PTK2B	2185	protein tyrosine kinase 2 beta	regulation of inositol trisphosphate biosynthetic process	Biological process	-
SLC3A1	6519	solute carrier family 3 (amino acid transporter heavy chain), member 1	catalytic activity	Molecular function	-
SLC15A4	121260	solute carrier family 15 (oligopeptide transporter), member 4	L-histidine transmembrane transport	Biological process	-
FGB	2244	fibrinogen beta chain	positive regulation of protein secretion	Biological process	19193866
RAB18	22931	RAB18, member RAS oncogene family	plasma membrane	Cellular component	-
RPL41	6171	ribosomal protein L41	viral life cycle	Biological process	-
RBM3	5935	RNA binding motif (RNP1, RRM) protein 3	translation	Biological process	-
TACR2	6865	tachykinin receptor 2	tachykinin receptor activity	Molecular function	8307161
CCM2	83605	cerebral cavernous malformation 2	endothelial tube morphogenesis	Biological process	19151727
ST20	400410	suppressor of tumorigenicity 20	protein homodimerization activity	Molecular function	-
PAK1	5058	p21 protein (Cdc42/Rac)-activated kinase 1	protein complex	Cellular component	11864573
DDX11	1663	DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11	extracellular exosome	Cellular component	18570454
AKAP3	10566	A kinase (PRKA) anchor protein 3	single fertilization	Biological process	10319321
UBC	7316	ubiquitin C	circadian rhythm	Biological process	-
JUN	3725	jun proto-oncogene	positive regulation of DNA replication	Biological process	-
CAD	790	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	cellular response to drug	Biological process	-
CCDC59	29080	coiled-coil domain containing 59	poly(A) RNA binding	Molecular function	22658674
EIF5	1983	eukaryotic translation initiation factor 5	protein binding	Molecular function	25416956
ACOT12	134526	acyl-CoA thioesterase 12	pyruvate metabolic process	Biological process	-
EPHB1	2047	EPH receptor B1	extracellular exosome	Cellular component	20458337
LPGAT1	9926	lysophosphatidylglycerol acyltransferase 1	endoplasmic reticulum membrane	Cellular component	-
PRDM14	63978	PR domain containing 14	metal ion binding	Molecular function	-
SPARC	6678	secreted protein, acidic, cysteine-rich (osteonectin)	cell surface	Cellular component	15389586
ABL1	25	ABL proto-oncogene 1, non-receptor tyrosine kinase	muscle cell differentiation	Biological process	-
MUC12	10071	mucin 12, cell surface associated	O-glycan processing	Biological process	-
PEX26	55670	peroxisomal biogenesis factor 26	protein complex binding	Molecular function	16854980
PCTP	58488	phosphatidylcholine transfer protein	phosphatidylcholine transporter activity	Molecular function	10500206
SNX25	83891	sorting nexin 25	protein transport	Biological process	-
PAX8	7849	paired box 8	positive regulation of metanephric DCT cell differentiation	Biological process	-
ATXN3L	92552	ataxin 3-like	mitochondrial matrix	Cellular component	-
APC	324	adenomatous polyposis coli	cell-cell adherens junction	Cellular component	16611247
IFT20	90410	intraflagellar transport 20	smoothened signaling pathway	Biological process	-
GSK3B	2932	glycogen synthase kinase 3 beta	tau protein binding	Molecular function	-
ZNF730	100129543	zinc finger protein 730	DNA binding	Molecular function	-
ZNF774	342132	zinc finger protein 774	DNA binding	Molecular function	-
PKD1	5310	polycystic kidney disease 1 (autosomal dominant)	mesonephric tubule development	Biological process	11891195
CLIC5	53405	chloride intracellular channel 5	cell cortex	Cellular component	-
CRYBB1	1414	crystallin, beta B1	structural constituent of eye lens	Molecular function	-
GLI3	2737	GLI family zinc finger 3	primary cilium	Cellular component	-
AKR1B10	57016	aldo-keto reductase family 1, member B10 (aldose reductase)	oxidation-reduction process	Biological process	-
FAM129A	116496	family with sequence similarity 129, member A	extracellular exosome	Cellular component	19199708
HNRNPD	3184	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	gene expression	Biological process	-
PRKCG	5582	protein kinase C, gamma	protein kinase activity	Molecular function	15808853
NCOA6	23054	nuclear receptor coactivator 6	myeloid cell differentiation	Biological process	11302752
SRC	6714	SRC proto-oncogene, non-receptor tyrosine kinase	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	19767770
CCL13	6357	chemokine (C-C motif) ligand 13	extracellular space	Cellular component	-
NPTX1	4884	neuronal pentraxin I	transport	Biological process	8884281
IRAK2	3656	interleukin-1 receptor-associated kinase 2	toll-like receptor 10 signaling pathway	Biological process	-
LZTFL1	54585	leucine zipper transcription factor-like 1	cytosol	Cellular component	-
FASLG	356	Fas ligand (TNF superfamily, member 6)	cytokine activity	Molecular function	-
MCM7	4176	minichromosome maintenance complex component 7	ATP binding	Molecular function	-
PEX2	5828	peroxisomal biogenesis factor 2	cholesterol homeostasis	Biological process	-
IFNA2	3440	interferon, alpha 2	extracellular space	Cellular component	-
HTRA2	27429	HtrA serine peptidase 2	regulation of mitochondrion degradation	Biological process	24522549
ARHGAP1	392	Rho GTPase activating protein 1	extracellular exosome	Cellular component	19056867
GRM8	2918	glutamate receptor, metabotropic 8	group III metabotropic glutamate receptor activity	Molecular function	-
PTPRB	5787	protein tyrosine phosphatase, receptor type, B	dephosphorylation	Biological process	19116766
ANXA9	8416	annexin A9	cell surface	Cellular component	10899159
DTWD2	285605	DTW domain containing 2	positive regulation of protein targeting to mitochondrion	Biological process	24270810
SPAG4	6676	sperm associated antigen 4	integral component of membrane	Cellular component	-
TINAGL1	64129	tubulointerstitial nephritis antigen-like 1	lysosome	Cellular component	-
TBK1	29110	TANK-binding kinase 1	protein binding	Molecular function	14743216
HIST1H2BN	8341	histone cluster 1, H2bn	chromatin organization	Biological process	-
TAF1C	9013	TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa	DNA binding	Molecular function	-
SLC7A10	56301	solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10	ion transport	Biological process	-
SULT1A2	6799	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2	steroid metabolic process	Biological process	-
RNF225	646862	ring finger protein 225	integral component of membrane	Cellular component	-
UCP3	7352	uncoupling protein 3 (mitochondrial, proton carrier)	response to glucocorticoid	Biological process	-
LPA	4018	lipoprotein, Lp(a)	mononuclear cell migration	Biological process	-
NUP62	23636	nucleoporin 62kDa	ubiquitin binding	Molecular function	-
TBX18	9096	T-box 18	somitogenesis	Biological process	-
ZNF624	57547	zinc finger protein 624	metal ion binding	Molecular function	-
COL11A2	1302	collagen, type XI, alpha 2	sensory perception of sound	Biological process	10581026
JAK2	3717	Janus kinase 2	positive regulation of sequence-specific DNA binding transcription factor activity	Biological process	-
MAGED1	9500	melanoma antigen family D1	negative regulation of transcription, DNA-templated	Biological process	-
JUP	3728	junction plakoglobin	bundle of His cell-Purkinje myocyte adhesion involved in cell communication	Biological process	17924338
PTGS2	5743	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	inflammatory response	Biological process	-
ADGRG1	9289	adhesion G protein-coupled receptor G1	collagen binding	Molecular function	-
HSPG2	3339	heparan sulfate proteoglycan 2	chondroitin sulfate metabolic process	Biological process	-
NR2F6	2063	nuclear receptor subfamily 2, group F, member 6	DNA binding	Molecular function	2905047
BCL2	596	B-cell CLL/lymphoma 2	cellular response to DNA damage stimulus	Biological process	17875758
MAPK11	5600	mitogen-activated protein kinase 11	ATP binding	Molecular function	-
KDELR2	11014	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2	Golgi apparatus	Cellular component	1316805
ZNF273	10793	zinc finger protein 273	nucleus	Cellular component	-
RPS9	6203	ribosomal protein S9	cytosol	Cellular component	-
POU3F3	5455	POU class 3 homeobox 3	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
HCK	3055	HCK proto-oncogene, Src family tyrosine kinase	cytokine-mediated signaling pathway	Biological process	18538446
AVP	551	arginine vasopressin	dendrite	Cellular component	-
SUPT20HL1	100130302	suppressor of Ty 20 homolog (S. cerevisiae)-like 1	SAGA complex	Cellular component	-
FAM198B	51313	family with sequence similarity 198, member B	Golgi apparatus	Cellular component	-
HCRTR2	3062	hypocretin (orexin) receptor 2	feeding behavior	Biological process	-
CHMP1A	5119	charged multivesicular body protein 1A	ESCRT III complex	Cellular component	-
ATF3	467	activating transcription factor 3	transcription regulatory region DNA binding	Molecular function	8622660
WAPAL	23063	wings apart-like homolog (Drosophila)	mitotic cell cycle	Biological process	-
ARL13B	200894	ADP-ribosylation factor-like 13B	heart looping	Biological process	-
TGFB2	7042	transforming growth factor, beta 2	negative regulation of macrophage cytokine production	Biological process	20875417
TNFRSF11A	8792	tumor necrosis factor receptor superfamily, member 11a, NFKB activator	TNFSF11-mediated signaling pathway	Biological process	18606301
CYTH2	9266	cytohesin 2	cytoplasm	Cellular component	17398095
PPP5C	5536	protein phosphatase 5, catalytic subunit	cytoplasm	Cellular component	-
SOX2	6657	SRY (sex determining region Y)-box 2	sequence-specific DNA binding transcription factor activity	Molecular function	7849401
LRRIQ3	127255	leucine-rich repeats and IQ motif containing 3	protein binding	Molecular function	25416956
C8A	731	complement component 8, alpha polypeptide	extracellular space	Cellular component	6771072
DRD2	1813	dopamine receptor D2	regulation of heart rate	Biological process	-
CDH3	1001	cadherin 3, type 1, P-cadherin (placental)	positive regulation of melanin biosynthetic process	Biological process	23334344
CDC42	998	cell division cycle 42	neuron fate determination	Biological process	-
ARGLU1	55082	arginine and glutamate rich 1	mitochondrion	Cellular component	-
MTOR	2475	mechanistic target of rapamycin (serine/threonine kinase)	positive regulation of gene expression	Biological process	17028174
KRT36	8689	keratin 36, type I	regulation of keratinocyte differentiation	Biological process	-
PCSK5	5125	proprotein convertase subtilisin/kexin type 5	anterior/posterior pattern specification	Biological process	18519639
ERCC3	2071	excision repair cross-complementation group 3	transcription from RNA polymerase I promoter	Biological process	-
CHST2	9435	carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2	sulfotransferase activity	Molecular function	9722682
E2F7	144455	E2F transcription factor 7	nucleus	Cellular component	-
MIF	4282	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	positive regulation of protein kinase A signaling	Biological process	17045821
BRCA2	675	breast cancer 2, early onset	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	Biological process	-
SGK1	6446	serum/glucocorticoid regulated kinase 1	long-term memory	Biological process	20530112
BHLHA9	727857	basic helix-loop-helix family, member a9	transcription, DNA-templated	Biological process	-
CISH	1154	cytokine inducible SH2-containing protein	plasma membrane	Cellular component	-
FAM90A23P	645572	family with sequence similarity 90, member A23 pseudogene	zinc ion binding	Molecular function	-
GBP2	2634	guanylate binding protein 2, interferon-inducible	type I interferon signaling pathway	Biological process	-
PTCH1	5727	patched 1	heart morphogenesis	Biological process	-
SEMA5B	54437	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B	cell differentiation	Biological process	-
HDAC4	9759	histone deacetylase 4	protein binding	Molecular function	10869435
LCK	3932	LCK proto-oncogene, Src family tyrosine kinase	positive regulation of intrinsic apoptotic signaling pathway	Biological process	-
NT5C2	22978	5'-nucleotidase, cytosolic II	protein binding	Molecular function	16189514
PSMA8	143471	proteasome (prosome, macropain) subunit, alpha type, 8	antigen processing and presentation of exogenous peptide antigen via MHC class I	Biological process	-
SERPINA5	5104	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5	serine-type endopeptidase inhibitor activity	Molecular function	10340997
GP5	2814	glycoprotein V (platelet)	plasma membrane	Cellular component	-
ARID3A	1820	AT rich interactive domain 3A (BRIGHT-like)	protein binding	Molecular function	19214191
HES5	388585	hes family bHLH transcription factor 5	specification of loop of Henle identity	Biological process	-
AVPR2	554	arginine vasopressin receptor 2	positive regulation of protein ubiquitination	Biological process	19372219
HEXIM1	10614	hexamethylene bis-acetamide inducible 1	nucleoplasm	Cellular component	-
ADAMTS1	9510	ADAM metallopeptidase with thrombospondin type 1 motif, 1	cytoplasmic vesicle	Cellular component	-
HDAC10	83933	histone deacetylase 10	regulation of transcription, DNA-templated	Biological process	11861901
RBFOX2	23543	RNA binding protein, fox-1 homolog (C. elegans) 2	RNA binding	Molecular function	11875103
CLPP	8192	caseinolytic mitochondrial matrix peptidase proteolytic subunit	protein binding	Molecular function	11923310
TNNI3	7137	troponin I type 3 (cardiac)	sarcomere	Cellular component	16754800
TFCP2	7024	transcription factor CP2	sequence-specific DNA binding transcription factor activity	Molecular function	8157699
EXOC6	54536	exocyst complex component 6	membrane organization	Biological process	-
CXXC1	30827	CXXC finger protein 1	regulation of transcription, DNA-templated	Biological process	10688657
POLR2L	5441	polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa	viral process	Biological process	-
PINK1	65018	PTEN induced putative kinase 1	regulation of synaptic vesicle transport	Biological process	21563316
HOXB3	3213	homeobox B3	anterior/posterior pattern specification	Biological process	-
GSKIP	51527	GSK3B interacting protein	cytoplasm	Cellular component	-
GAS6	2621	growth arrest-specific 6	protein targeting to plasma membrane	Biological process	16359517
NIFK	84365	nucleolar protein interacting with the FHA domain of MKI67	condensed nuclear chromosome	Cellular component	11342549
PKN2	5586	protein kinase N2	RNA polymerase binding	Molecular function	15364941
PPP3R1	5534	protein phosphatase 3, regulatory subunit B, alpha	positive regulation of NFAT protein import into nucleus	Biological process	22688515
GATM	2628	glycine amidinotransferase (L-arginine:glycine amidinotransferase)	response to mercury ion	Biological process	-
NOTUM	147111	notum pectinacetylesterase homolog (Drosophila)	extracellular region	Cellular component	-
HDAC6	10013	histone deacetylase 6	response to misfolded protein	Biological process	14675537
CERS3	204219	ceramide synthase 3	sphingosine N-acyltransferase activity	Molecular function	-
IGFBP5	3488	insulin-like growth factor binding protein 5	cellular response to cAMP	Biological process	7559606
ERVFRD-1	405754	endogenous retrovirus group FRD, member 1	syncytium formation	Biological process	23492904
BFSP1	631	beaded filament structural protein 1, filensin	cytoplasm	Cellular component	-
CACNB2	783	calcium channel, voltage-dependent, beta 2 subunit	axon guidance	Biological process	-
SLC12A2	6558	solute carrier family 12 (sodium/potassium/chloride transporter), member 2	transepithelial chloride transport	Biological process	12946942
HSP90B1	7184	heat shock protein 90kDa beta (Grp94), member 1	protein phosphatase binding	Molecular function	19000834
VTI1A	143187	vesicle transport through interaction with t-SNAREs 1A	Golgi apparatus	Cellular component	19224922
MRGBP	55257	MRG/MORF4L binding protein	H4/H2A histone acetyltransferase complex	Cellular component	-
SULT1B1	27284	sulfotransferase family, cytosolic, 1B, member 1	aryl sulfotransferase activity	Molecular function	-
ZMYND8	23613	zinc finger, MYND-type containing 8	RNA polymerase II transcription corepressor activity	Molecular function	-
RAP1GAP	5909	RAP1 GTPase activating protein	cytosol	Cellular component	-
LRG1	116844	leucine-rich alpha-2-glycoprotein 1	extracellular exosome	Cellular component	23376485
SLC15A3	51296	solute carrier family 15 (oligopeptide transporter), member 3	intracellular membrane-bounded organelle	Cellular component	-
NLGN4X	57502	neuroligin 4, X-linked	dendrite	Cellular component	19726642
TET3	200424	tet methylcytosine dioxygenase 3	gene expression	Biological process	-
SLC17A8	246213	solute carrier family 17 (vesicular glutamate transporter), member 8	ion transport	Biological process	-
ZFYVE9	9372	zinc finger, FYVE domain containing 9	protein binding	Molecular function	12154125
NGF	4803	nerve growth factor (beta polypeptide)	extrinsic apoptotic signaling pathway in absence of ligand	Biological process	-
UBE2B	7320	ubiquitin-conjugating enzyme E2B	response to UV	Biological process	1717990
NUP160	23279	nucleoporin 160kDa	viral transcription	Biological process	-
ZYX	7791	zyxin	focal adhesion	Cellular component	-
EYS	346007	eyes shut homolog (Drosophila)	detection of light stimulus involved in visual perception	Biological process	18836446
NF2	4771	neurofibromin 2 (merlin)	negative regulation of MAPK cascade	Biological process	-
PDX1	3651	pancreatic and duodenal homeobox 1	positive regulation of cell proliferation	Biological process	-
TIMM50	92609	translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)	protein targeting to mitochondrion	Biological process	-
ZNF540	163255	zinc finger protein 540	nucleoplasm	Cellular component	-
KRR1	11103	KRR1, small subunit (SSU) processome component, homolog (yeast)	nucleolus	Cellular component	-
KLF1	10661	Kruppel-like factor 1 (erythroid)	embryonic hemopoiesis	Biological process	-
HYPK	25764	huntingtin interacting protein K	nucleus	Cellular component	-
SERBP1	26135	SERPINE1 mRNA binding protein 1	regulation of mRNA stability	Biological process	11001948
PRKAA2	5563	protein kinase, AMP-activated, alpha 2 catalytic subunit	negative regulation of TOR signaling	Biological process	-
OR4C5	79346	olfactory receptor, family 4, subfamily C, member 5 (gene/pseudogene)	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
BARX1	56033	BARX homeobox 1	digestive system development	Biological process	-
NUTF2	10204	nuclear transport factor 2	protein import into nucleus, translocation	Biological process	18266911
FAM160A2	84067	family with sequence similarity 160, member A2	endosome organization	Biological process	18799622
APOA1BP	128240	apolipoprotein A-I binding protein	protein homodimerization activity	Molecular function	-
IRAK2	3656	interleukin-1 receptor-associated kinase 2	toll-like receptor 4 signaling pathway	Biological process	-
STATH	6779	statherin	saliva secretion	Biological process	1718282
CSNK2A1	1457	casein kinase 2, alpha 1 polypeptide	Sin3 complex	Cellular component	17827154
GTF2F1	2962	general transcription factor IIF, polypeptide 1, 74kDa	phosphatase activator activity	Molecular function	12721286
GLCE	26035	glucuronic acid epimerase	glycosaminoglycan metabolic process	Biological process	-
ZNF582	147948	zinc finger protein 582	regulation of transcription, DNA-templated	Biological process	-
BMPR1B	658	bone morphogenetic protein receptor, type IB	transforming growth factor beta receptor activity, type I	Molecular function	-
POSTN	10631	periostin, osteoblast specific factor	heparin binding	Molecular function	-
MVK	4598	mevalonate kinase	ATP binding	Molecular function	-
MRPL1	65008	mitochondrial ribosomal protein L1	protein binding	Molecular function	25416956
CLEC4M	10332	C-type lectin domain family 4, member M	membrane	Cellular component	11337487
TPPP3	51673	tubulin polymerization-promoting protein family member 3	microtubule	Cellular component	-
BANP	54971	BTG3 associated nuclear protein	negative regulation of protein catabolic process	Biological process	-
HDDC3	374659	HD domain containing 3	protein binding	Molecular function	16189514
S100A8	6279	S100 calcium binding protein A8	sequestering of zinc ion	Biological process	22489132
ADAMTSL1	92949	ADAMTS-like 1	endoplasmic reticulum lumen	Cellular component	-
MERTK	10461	MER proto-oncogene, tyrosine kinase	natural killer cell differentiation	Biological process	-
MESP2	145873	mesoderm posterior basic helix-loop-helix transcription factor 2	mesodermal cell migration	Biological process	-
ZFY	7544	zinc finger protein, Y-linked	DNA binding	Molecular function	-
SCN5A	6331	sodium channel, voltage gated, type V alpha subunit	positive regulation of epithelial cell proliferation	Biological process	-
MAEL	84944	maelstrom spermatogenic transposon silencer	autosome	Cellular component	-
RBPJ	3516	recombination signal binding protein for immunoglobulin kappa J region	positive regulation of ephrin receptor signaling pathway	Biological process	-
ZFPM1	161882	zinc finger protein, FOG family member 1	cardiac muscle tissue morphogenesis	Biological process	-
PTGIS	5740	prostaglandin I2 (prostacyclin) synthase	NAD metabolic process	Biological process	-
SASH1	23328	SAM and SH3 domain containing 1	positive regulation of p38MAPK cascade	Biological process	23776175
LCAT	3931	lecithin-cholesterol acyltransferase	phosphatidylcholine-sterol O-acyltransferase activity	Molecular function	11966470
B4GAT1	11041	beta-1,4-glucuronyltransferase 1	Golgi membrane	Cellular component	-
MUCL1	118430	mucin-like 1	post-translational protein modification	Biological process	-
MPP7	143098	membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)	protein domain specific binding	Molecular function	17332497
KCNG3	170850	potassium channel, voltage gated modifier subfamily G, member 3	voltage-gated potassium channel complex	Cellular component	19074135
GSK3B	2932	glycogen synthase kinase 3 beta	response to lithium ion	Biological process	-
HSD3B1	3283	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1	endoplasmic reticulum membrane	Cellular component	-
PSMC3	5702	proteasome (prosome, macropain) 26S subunit, ATPase, 3	nucleus	Cellular component	21630459
TAB2	23118	TGF-beta activated kinase 1/MAP3K7 binding protein 2	plasma membrane	Cellular component	-
RAC3	5881	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	neuron projection development	Biological process	-
BCL2L1	598	BCL2-like 1	growth	Biological process	-
HOXA13	3209	homeobox A13	vasculogenesis	Biological process	-
BEX1	55859	brain expressed, X-linked 1	RNA polymerase II activating transcription factor binding	Molecular function	16314316
NCSTN	23385	nicastrin	protein binding	Molecular function	12297508
GPR149	344758	G protein-coupled receptor 149	antral ovarian follicle growth	Biological process	-
METTL1	4234	methyltransferase like 1	tRNA binding	Molecular function	-
PARK7	11315	parkinson protein 7	protein binding	Molecular function	11477070
NME1	4830	NME/NM23 nucleoside diphosphate kinase 1	ruffle membrane	Cellular component	16814409
TAZ	6901	tafazzin	hemopoiesis	Biological process	17043667
COL13A1	1305	collagen, type XIII, alpha 1	endoplasmic reticulum lumen	Cellular component	-
PEX3	8504	peroxisomal biogenesis factor 3	peroxisome membrane biogenesis	Biological process	-
PGLYRP3	114771	peptidoglycan recognition protein 3	extracellular region	Cellular component	-
PRDM2	7799	PR domain containing 2, with ZNF domain	regulation of transcription, DNA-templated	Biological process	7590293
SPA17	53340	sperm autoantigenic protein 17	binding of sperm to zona pellucida	Biological process	-
MDM2	4193	MDM2 proto-oncogene, E3 ubiquitin protein ligase	negative regulation of cell cycle arrest	Biological process	9529249
TBP	6908	TATA box binding protein	transcription initiation from RNA polymerase I promoter	Biological process	-
SLC6A16	28968	solute carrier family 6, member 16	transmembrane transport	Biological process	-
WNT2B	7482	wingless-type MMTV integration site family, member 2B	neuron differentiation	Biological process	-
NECAP2	55707	NECAP endocytosis associated 2	protein transport	Biological process	-
RBBP7	5931	retinoblastoma binding protein 7	transcription, DNA-templated	Biological process	-
INPP5D	3635	inositol polyphosphate-5-phosphatase, 145kDa	positive regulation of B cell differentiation	Biological process	-
CD34	947	CD34 molecule	endothelial cell proliferation	Biological process	21835908
PGK1	5230	phosphoglycerate kinase 1	phosphoglycerate kinase activity	Molecular function	-
ANAPC13	25847	anaphase promoting complex subunit 13	protein K11-linked ubiquitination	Biological process	18485873
S1PR3	1903	sphingosine-1-phosphate receptor 3	regulation of interleukin-1 beta production	Biological process	-
IDUA	3425	iduronidase, alpha-L-	chondroitin sulfate catabolic process	Biological process	-
PDIA5	10954	protein disulfide isomerase family A, member 5	protein disulfide isomerase activity	Molecular function	7556671
WDPCP	51057	WD repeat containing planar cell polarity effector	camera-type eye development	Biological process	-
MSMO1	6307	methylsterol monooxygenase 1	steroid metabolic process	Biological process	8663358
RIPPLY1	92129	ripply transcriptional repressor 1	protein binding	Molecular function	25416956
MED16	10025	mediator complex subunit 16	receptor activity	Molecular function	12218053
INPPL1	3636	inositol polyphosphate phosphatase-like 1	actin binding	Molecular function	-
CD36	948	CD36 molecule (thrombospondin receptor)	receptor-mediated endocytosis	Biological process	-
CTNNA1	1495	catenin (cadherin-associated protein), alpha 1, 102kDa	negative regulation of neuroblast proliferation	Biological process	-
AGPAT2	10555	1-acylglycerol-3-phosphate O-acyltransferase 2	positive regulation of cytokine-mediated signaling pathway	Biological process	9212163
CCK	885	cholecystokinin	protein kinase C-activating G-protein coupled receptor signaling pathway	Biological process	-
SKIL	6498	SKI-like proto-oncogene	protein heterotrimerization	Biological process	8514802
PDGFRB	5159	platelet-derived growth factor receptor, beta polypeptide	neurotrophin TRK receptor signaling pathway	Biological process	-
IL36G	56300	interleukin 36, gamma	negative regulation of myoblast differentiation	Biological process	-
SCNN1G	6340	sodium channel, non voltage gated 1 gamma subunit	multicellular organismal water homeostasis	Biological process	24124190
E2F3	1871	E2F transcription factor 3	nucleoplasm	Cellular component	-
HES5	388585	hes family bHLH transcription factor 5	neuronal stem cell maintenance	Biological process	19682396
BHLHE41	79365	basic helix-loop-helix family, member e41	negative regulation of transcription from RNA polymerase II promoter	Biological process	14672706
TACR1	6869	tachykinin receptor 1	positive regulation of saliva secretion	Biological process	-
DLG1	1739	discs, large homolog 1 (Drosophila)	immunological synapse	Cellular component	19841189
DHCR24	1718	24-dehydrocholesterol reductase	response to hormone	Biological process	-
TNNC2	7125	troponin C type 2 (fast)	regulation of muscle contraction	Biological process	2373703
TLR2	7097	toll-like receptor 2	I-kappaB phosphorylation	Biological process	19740627
MATK	4145	megakaryocyte-associated tyrosine kinase	non-membrane spanning protein tyrosine kinase activity	Molecular function	-
DUSP12	11266	dual specificity phosphatase 12	protein tyrosine phosphatase activity	Molecular function	-
PHF8	23133	PHD finger protein 8	histone demethylase activity	Molecular function	19843542
RSC1A1	6248	regulatory solute carrier protein, family 1, member 1	regulation of transcription, DNA-templated	Biological process	-
ME3	10873	malic enzyme 3, NADP(+)-dependent, mitochondrial	oxaloacetate decarboxylase activity	Molecular function	-
PNLIPRP2	5408	pancreatic lipase-related protein 2	phospholipid catabolic process	Biological process	18702514
NR1D2	9975	nuclear receptor subfamily 1, group D, member 2	positive regulation of transcription, DNA-templated	Biological process	-
CLEC4M	10332	C-type lectin domain family 4, member M	virus receptor activity	Molecular function	15496474
SEC16B	89866	SEC16 homolog B (S. cerevisiae)	endoplasmic reticulum organization	Biological process	21768384
ATP4A	495	ATPase, H+/K+ exchanging, alpha polypeptide	sodium:potassium-exchanging ATPase activity	Molecular function	-
HMGCL	3155	3-hydroxymethyl-3-methylglutaryl-CoA lyase	small molecule metabolic process	Biological process	-
SNX8	29886	sorting nexin 8	endosome	Cellular component	-
AK9	221264	adenylate kinase 9	ATP binding	Molecular function	-
EPHB6	2051	EPH receptor B6	ephrin receptor activity	Molecular function	-
SKOR1	390598	SKI family transcriptional corepressor 1	neuronal cell body	Cellular component	17292623
IFT20	90410	intraflagellar transport 20	regulation of canonical Wnt signaling pathway	Biological process	-
DDX51	317781	DEAD (Asp-Glu-Ala-Asp) box polypeptide 51	ATP binding	Molecular function	-
RNF157	114804	ring finger protein 157	zinc ion binding	Molecular function	-
DICER1	23405	dicer 1, ribonuclease type III	RNA phosphodiester bond hydrolysis, endonucleolytic	Biological process	21753850
GABRQ	55879	gamma-aminobutyric acid (GABA) A receptor, theta	GABA-A receptor activity	Molecular function	-
OR1F12	442179	olfactory receptor, family 1, subfamily F, member 12	plasma membrane	Cellular component	-
MRPL23	6150	mitochondrial ribosomal protein L23	mitochondrial translational initiation	Biological process	-
ACP2	53	acid phosphatase 2, lysosomal	acid phosphatase activity	Molecular function	-
KRTAP1-4	728255	keratin associated protein 1-4	keratin filament	Cellular component	-
HSPB1	3315	heat shock 27kDa protein 1	protein kinase C inhibitor activity	Molecular function	-
AVPR1B	553	arginine vasopressin receptor 1B	cellular response to hormone stimulus	Biological process	-
DDX54	79039	DEAD (Asp-Glu-Ala-Asp) box polypeptide 54	nucleus	Cellular component	12466272
TK2	7084	thymidine kinase 2, mitochondrial	deoxycytidine metabolic process	Biological process	-
TESC	54997	tescalcin	negative regulation of protein kinase activity	Biological process	-
LRTOMT	220074	leucine rich transmembrane and O-methyltransferase domain containing	sensory perception of sound	Biological process	18794526
TLN2	83660	talin 2	protein binding	Molecular function	10320934
PAK2	5062	p21 protein (Cdc42/Rac)-activated kinase 2	regulation of MAPK cascade	Biological process	-
EXOC4	60412	exocyst complex component 4	protein transport	Biological process	-
WTIP	126374	Wilms tumor 1 interacting protein	adherens junction	Cellular component	-
VCAN	1462	versican	osteoblast differentiation	Biological process	16210410
HYAL2	8692	hyaluronoglucosaminidase 2	anchored component of external side of plasma membrane	Cellular component	19443707
C16orf54	283897	chromosome 16 open reading frame 54	integral component of membrane	Cellular component	-
BYSL	705	bystin-like	trophectodermal cell differentiation	Biological process	-
NGDN	25983	neuroguidin, EIF4E binding protein	cytoplasm	Cellular component	-
ADAT1	23536	adenosine deaminase, tRNA-specific 1	metal ion binding	Molecular function	-
GGN	199720	gametogenetin	protein dimerization activity	Molecular function	-
PRSS8	5652	protease, serine, 8	extracellular region	Cellular component	10077646
UROD	7389	uroporphyrinogen decarboxylase	protein binding	Molecular function	25416956
MSH4	4438	mutS homolog 4	meiotic mismatch repair	Biological process	-
PEG3	5178	paternally expressed 3	genetic imprinting	Biological process	-
VAMP3	9341	vesicle-associated membrane protein 3	cytosol	Cellular component	22589474
MAN2B1	4125	mannosidase, alpha, class 2B, member 1	extracellular exosome	Cellular component	23376485
C19orf80	55908	chromosome 19 open reading frame 80	type B pancreatic cell proliferation	Biological process	-
OAZ1	4946	ornithine decarboxylase antizyme 1	regulation of cellular amino acid metabolic process	Biological process	-
GLIPR1	11010	GLI pathogenesis-related 1	plasma membrane	Cellular component	-
TFRC	7037	transferrin receptor	perinuclear region of cytoplasm	Cellular component	20202662
LAMB1	3912	laminin, beta 1	extracellular matrix organization	Biological process	-
ICAM1	3383	intercellular adhesion molecule 1	response to ethanol	Biological process	-
LRRC7	57554	leucine rich repeat containing 7	cell junction	Cellular component	-
ANKRD42	338699	ankyrin repeat domain 42	positive regulation of NF-kappaB transcription factor activity	Biological process	-
NOS1	4842	nitric oxide synthase 1 (neuronal)	ion channel binding	Molecular function	21536106
MYO5A	4644	myosin VA (heavy chain 12, myoxin)	late endosome	Cellular component	24006491
CYFIP2	26999	cytoplasmic FMR1 interacting protein 2	protein binding	Molecular function	11438699
SLC24A2	25769	solute carrier family 24 (sodium/potassium/calcium exchanger), member 2	learning	Biological process	-
SIRT2	22933	sirtuin 2	cellular lipid catabolic process	Biological process	-
MAD1L1	8379	MAD1 mitotic arrest deficient-like 1 (yeast)	cell division	Biological process	-
MZT2A	653784	mitotic spindle organizing protein 2A	gamma-tubulin ring complex	Cellular component	-
ACKR1	2532	atypical chemokine receptor 1 (Duffy blood group)	defense response	Biological process	10570183
SIN3A	25942	SIN3 transcription regulator family member A	nucleolus	Cellular component	-
TAS2R45	259291	taste receptor, type 2, member 45	plasma membrane	Cellular component	-
EDA	1896	ectodysplasin A	cell differentiation	Biological process	-
CDCA8	55143	cell division cycle associated 8	midbody	Cellular component	22724069
MME	4311	membrane metallo-endopeptidase	protein binding	Molecular function	17342744
MYCBP2	23077	MYC binding protein 2, E3 ubiquitin protein ligase	regulation of protein localization	Biological process	-
GAS1	2619	growth arrest-specific 1	embryonic digit morphogenesis	Biological process	-
RPGRIP1L	23322	RPGRIP1-like	cilium assembly	Biological process	-
GABRR1	2569	gamma-aminobutyric acid (GABA) A receptor, rho 1	cell junction	Cellular component	-
RAD23B	5887	RAD23 homolog B (S. cerevisiae)	cytoplasm	Cellular component	-
FH	2271	fumarate hydratase	mitochondrion	Cellular component	-
SMARCD3	6604	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3	regulation of protein binding	Biological process	-
HIPK2	28996	homeodomain interacting protein kinase 2	nucleus	Cellular component	-
DNAJA4	55466	DnaJ (Hsp40) homolog, subfamily A, member 4	unfolded protein binding	Molecular function	21231916
PPBP	5473	pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)	glucose transport	Biological process	4005226
DDX41	51428	DEAD (Asp-Glu-Ala-Asp) box polypeptide 41	mRNA splicing, via spliceosome	Biological process	11991638
STRADB	55437	STE20-related kinase adaptor beta	insulin receptor signaling pathway	Biological process	-
GRIN2A	2903	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	neuronal postsynaptic density	Cellular component	-
TCOF1	6949	Treacher Collins-Franceschetti syndrome 1	nucleolus	Cellular component	-
CLCN4	1183	chloride channel, voltage-sensitive 4	antiporter activity	Molecular function	-
CBLN1	869	cerebellin 1 precursor	protein homodimerization activity	Molecular function	-
SMIM3	85027	small integral membrane protein 3	protein binding	Molecular function	16189514
CD4	920	CD4 molecule	protein homodimerization activity	Molecular function	12444132
VCPIP1	80124	valosin containing protein (p97)/p47 complex interacting protein 1	protein K48-linked deubiquitination	Biological process	23827681
PRKCG	5582	protein kinase C, gamma	cytosol	Cellular component	-
TNKS	8658	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase	NAD+ ADP-ribosyltransferase activity	Molecular function	-
SERPINF1	5176	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1	perinuclear region of cytoplasm	Cellular component	-
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	lateral plasma membrane	Cellular component	12072559
FOXO6	100132074	forkhead box O6	anatomical structure morphogenesis	Biological process	-
HDAC2	3066	histone deacetylase 2	ESC/E(Z) complex	Cellular component	20075857
MDM2	4193	MDM2 proto-oncogene, E3 ubiquitin protein ligase	cellular response to vitamin B1	Biological process	-
RILP	83547	Rab interacting lysosomal protein	endosome transport via multivesicular body sorting pathway	Biological process	17010938
PSMD13	5719	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
PRIMPOL	201973	primase and polymerase (DNA-directed)	response to UV	Biological process	24240614
P2RX6	9127	purinergic receptor P2X, ligand gated ion channel, 6	channel activity	Molecular function	9242461
WBP11	51729	WW domain binding protein 11	rRNA processing	Biological process	-
ING4	51147	inhibitor of growth family, member 4	protein binding	Molecular function	12750254
SIAH2	6478	siah E3 ubiquitin protein ligase 2	protein ubiquitination	Biological process	-
ERCC5	2073	excision repair cross-complementation group 5	response to UV	Biological process	16167068
GABARAP	11337	GABA(A) receptor-associated protein	cell body	Cellular component	-
LONRF2	164832	LON peptidase N-terminal domain and ring finger 2	zinc ion binding	Molecular function	-
GGTLC2	91227	gamma-glutamyltransferase light chain 2	gamma-glutamyltransferase activity	Molecular function	18357469
KLF4	9314	Kruppel-like factor 4 (gut)	negative regulation of response to cytokine stimulus	Biological process	20551324
IFIT2	3433	interferon-induced protein with tetratricopeptide repeats 2	poly(A) RNA binding	Molecular function	22658674
PECAM1	5175	platelet/endothelial cell adhesion molecule 1	extracellular exosome	Cellular component	20458337
GEN1	348654	GEN1 Holliday junction 5' flap endonuclease	regulation of centrosome duplication	Biological process	23108668
OLFML1	283298	olfactomedin-like 1	extracellular region	Cellular component	-
PSMD2	5708	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	cellular nitrogen compound metabolic process	Biological process	-
CHST15	51363	carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15	glycosaminoglycan metabolic process	Biological process	-
UCP3	7352	uncoupling protein 3 (mitochondrial, proton carrier)	proton transport	Biological process	-
FASLG	356	Fas ligand (TNF superfamily, member 6)	regulation of extrinsic apoptotic signaling pathway via death domain receptors	Biological process	-
NHLRC1	378884	NHL repeat containing E3 ubiquitin protein ligase 1	autophagy	Biological process	-
SRF	6722	serum response factor (c-fos serum response element-binding transcription factor)	response to toxic substance	Biological process	12660819
ITCH	83737	itchy E3 ubiquitin protein ligase	ubiquitin-protein transferase activity	Molecular function	-
GGT1	2678	gamma-glutamyltransferase 1	anchored component of external side of plasma membrane	Cellular component	18357469
CHRNA1	1134	cholinergic receptor, nicotinic, alpha 1 (muscle)	cell junction	Cellular component	-
TGOLN2	10618	trans-golgi network protein 2	Golgi apparatus	Cellular component	-
PAF1	54623	Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)	chromatin binding	Molecular function	-
YLPM1	56252	YLP motif containing 1	nuclear speck	Cellular component	-
GARNL3	84253	GTPase activating Rap/RanGAP domain-like 3	GTPase activator activity	Molecular function	-
SPRR2D	6703	small proline-rich protein 2D	epidermis development	Biological process	8325635
SLC18A2	6571	solute carrier family 18 (vesicular monoamine transporter), member 2	response to zinc ion	Biological process	-
ATP1A3	478	ATPase, Na+/K+ transporting, alpha 3 polypeptide	nucleus	Cellular component	-
NODAL	4838	nodal growth differentiation factor	negative regulation of trophoblast cell migration	Biological process	21356369
BRAF	673	B-Raf proto-oncogene, serine/threonine kinase	glucose transport	Biological process	23010278
SSTR3	6753	somatostatin receptor 3	somatostatin receptor activity	Molecular function	-
GPT2	84706	glutamic pyruvate transaminase (alanine aminotransferase) 2	cellular nitrogen compound metabolic process	Biological process	-
MAST4	375449	microtubule associated serine/threonine kinase family member 4	magnesium ion binding	Molecular function	-
NRXN3	9369	neurexin 3	learning	Biological process	22209245
HTR4	3360	5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled	cytoplasm	Cellular component	15925089
GABARAPL1	23710	GABA(A) receptor-associated protein like 1	pre-autophagosomal structure	Cellular component	-
NTRK3	4916	neurotrophic tyrosine kinase, receptor, type 3	response to corticosterone	Biological process	-
CACTIN	58509	cactin, spliceosome C complex subunit	cellular response to interleukin-1	Biological process	20829348
JAZF1	221895	JAZF zinc finger 1	nucleus	Cellular component	-
SHROOM2	357	shroom family member 2	cytoskeleton	Cellular component	-
OR51E1	143503	olfactory receptor, family 51, subfamily E, member 1	integral component of membrane	Cellular component	-
XPNPEP1	7511	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble	protein homodimerization activity	Molecular function	18515364
PCDH12	51294	protocadherin 12	extracellular exosome	Cellular component	23376485
SLC3A2	6520	solute carrier family 3 (amino acid transporter heavy chain), member 2	melanosome	Cellular component	-
IST1	9798	increased sodium tolerance 1 homolog (yeast)	positive regulation of defense response to virus by host	Biological process	22020285
MAN2A2	4122	mannosidase, alpha, class 2A, member 2	Golgi membrane	Cellular component	-
PIP4K2B	8396	phosphatidylinositol-5-phosphate 4-kinase, type II, beta	cell surface receptor signaling pathway	Biological process	9038203
OR13C9	286362	olfactory receptor, family 13, subfamily C, member 9	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
CENPT	80152	centromere protein T	protein heterodimerization activity	Molecular function	-
RPS27A	6233	ribosomal protein S27a	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition	Biological process	-
CCSAP	126731	centriole, cilia and spindle-associated protein	regulation of embryonic development	Biological process	-
ELOVL6	79071	ELOVL fatty acid elongase 6	protein binding	Molecular function	20937905
CYP1A1	1543	cytochrome P450, family 1, subfamily A, polypeptide 1	epoxygenase P450 pathway	Biological process	-
NOTCH1	4851	notch 1	chromatin DNA binding	Molecular function	-
PDPK1	5170	3-phosphoinositide dependent protein kinase 1	blood coagulation	Biological process	-
RBMS1	5937	RNA binding motif, single stranded interacting protein 1	RNA binding	Molecular function	8041632
PSPN	5623	persephin	branching involved in ureteric bud morphogenesis	Biological process	-
STAB2	55576	stabilin 2	hyaluronan metabolic process	Biological process	-
PRDX4	10549	peroxiredoxin 4	oxidation-reduction process	Biological process	-
EVC2	132884	Ellis van Creveld syndrome 2	nucleus	Cellular component	-
TRUB1	142940	TruB pseudouridine (psi) synthase family member 1	mRNA pseudouridine synthesis	Biological process	-
CHST8	64377	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8	Golgi membrane	Cellular component	-
HDC	3067	histidine decarboxylase	protein binding	Molecular function	25416956
DNAJA3	9093	DnaJ (Hsp40) homolog, subfamily A, member 3	negative regulation of interferon-gamma-mediated signaling pathway	Biological process	11679576
LIG4	3981	ligase IV, DNA, ATP-dependent	cell proliferation	Biological process	-
OR2A25	392138	olfactory receptor, family 2, subfamily A, member 25	plasma membrane	Cellular component	-
CLEC4C	170482	C-type lectin domain family 4, member C	plasma membrane	Cellular component	-
CRYBA2	1412	crystallin, beta A2	molecular_function	Molecular function	-
ARRDC3	57561	arrestin domain containing 3	fat pad development	Biological process	-
ABCA11P	79963	ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene	ATPase activity	Molecular function	-
RAB7B	338382	RAB7B, member RAS oncogene family	positive regulation of interleukin-6 production	Biological process	20953574
SON	6651	SON DNA binding protein	mRNA processing	Biological process	21504830
NUP98	4928	nucleoporin 98kDa	nuclear membrane	Cellular component	11839768
CNEP1R1	255919	CTD nuclear envelope phosphatase 1 regulatory subunit 1	positive regulation of protein dephosphorylation	Biological process	22134922
TSPAN9	10867	tetraspanin 9	integral component of membrane	Cellular component	-
FBXO7	25793	F-box protein 7	ubiquitin-dependent protein catabolic process	Biological process	10531035
HNRNPUL2	221092	heterogeneous nuclear ribonucleoprotein U-like 2	nucleus	Cellular component	-
EXOSC3	51010	exosome component 3	isotype switching	Biological process	-
PLEKHG5	57449	pleckstrin homology domain containing, family G (with RhoGef domain) member 5	endothelial cell chemotaxis	Biological process	-
GABRA5	2558	gamma-aminobutyric acid (GABA) A receptor, alpha 5	transport	Biological process	1321750
SPATA25	128497	spermatogenesis associated 25	spermatogenesis	Biological process	19240080
GPX1	2876	glutathione peroxidase 1	hydrogen peroxide catabolic process	Biological process	15203190
KIF3B	9371	kinesin family member 3B	midbody	Cellular component	-
NPY5R	4889	neuropeptide Y receptor Y5	pancreatic polypeptide receptor activity	Molecular function	-
SYT3	84258	synaptotagmin III	plasma membrane	Cellular component	-
IL18RAP	8807	interleukin 18 receptor accessory protein	receptor activity	Molecular function	9792649
GDF11	10220	growth differentiation factor 11	extracellular space	Cellular component	-
NDUFA5	4698	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5	respiratory electron transport chain	Biological process	-
RHEBL1	121268	Ras homolog enriched in brain like 1	endomembrane system	Cellular component	-
POLB	5423	polymerase (DNA directed), beta	pyrimidine dimer repair	Biological process	-
TLR2	7097	toll-like receptor 2	triacyl lipopeptide binding	Molecular function	17889651
CACNA1C	775	calcium channel, voltage-dependent, L type, alpha 1C subunit	integral component of membrane	Cellular component	8392192
LRP6	4040	low density lipoprotein receptor-related protein 6	embryonic hindlimb morphogenesis	Biological process	-
RPP40	10799	ribonuclease P/MRP 40kDa subunit	tRNA processing	Biological process	-
PRDM1	639	PR domain containing 1, with ZNF domain	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	1851123
GLI3	2737	GLI family zinc finger 3	palate development	Biological process	-
CDH1	999	cadherin 1, type 1, E-cadherin (epithelial)	protein phosphatase binding	Molecular function	-
VCP	7415	valosin containing protein	ER-associated misfolded protein catabolic process	Biological process	24089527
MTERF4	130916	mitochondrial transcription termination factor 4	double-stranded DNA binding	Molecular function	-
EDA	1896	ectodysplasin A	salivary gland cavitation	Biological process	-
DUSP6	1848	dual specificity phosphatase 6	cell differentiation	Biological process	-
HTRA2	27429	HtrA serine peptidase 2	protein autoprocessing	Biological process	11602612
POLDIP3	84271	polymerase (DNA-directed), delta interacting protein 3	exon-exon junction complex	Cellular component	18423201
NFATC1	4772	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	intracellular signal transduction	Biological process	14749367
PITX2	5308	paired-like homeodomain 2	sequence-specific DNA binding transcription factor activity	Molecular function	11301317
KIF24	347240	kinesin family member 24	kinesin complex	Cellular component	-
SCN3B	55800	sodium channel, voltage gated, type III beta subunit	cardiac muscle contraction	Biological process	20042427
AGO4	192670	argonaute RISC catalytic component 4	double-stranded RNA binding	Molecular function	19966796
RASL11A	387496	RAS-like, family 11, member A	positive regulation of transcription from RNA polymerase I promoter	Biological process	-
CA4	762	carbonic anhydrase IV	brush border membrane	Cellular component	17409381
ARHGEF4	50649	Rho guanine nucleotide exchange factor (GEF) 4	ruffle membrane	Cellular component	-
CXCR2	3579	chemokine (C-X-C motif) receptor 2	chemokine-mediated signaling pathway	Biological process	-
ING4	51147	inhibitor of growth family, member 4	apoptotic process	Biological process	15251430
TMEM204	79652	transmembrane protein 204	regulation of vascular endothelial growth factor receptor signaling pathway	Biological process	-
SPON1	10418	spondin 1, extracellular matrix protein	post-translational protein modification	Biological process	-
STAG2	10735	stromal antigen 2	stem cell maintenance	Biological process	-
SIX3	6496	SIX homeobox 3	regulation of neural retina development	Biological process	-
CDC6	990	cell division cycle 6	cytosol	Cellular component	-
TCP11	6954	t-complex 11, testis-specific	multicellular organismal development	Biological process	1893875
CDK2	1017	cyclin-dependent kinase 2	cytoplasm	Cellular component	10767298
KPTN	11133	kaptin (actin binding protein)	microtubule organizing center	Cellular component	1372044
ELANE	1991	elastase, neutrophil expressed	response to yeast	Biological process	-
BSN	8927	bassoon presynaptic cytomatrix protein	synapse assembly	Biological process	-
STK11	6794	serine/threonine kinase 11	small molecule metabolic process	Biological process	-
MFI2	4241	antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5	extracellular exosome	Cellular component	19056867
EIF2B5	8893	eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa	oligodendrocyte development	Biological process	15217090
COPG1	22820	coatomer protein complex, subunit gamma 1	retrograde vesicle-mediated transport, Golgi to ER	Biological process	-
CHGB	1114	chromogranin B	extracellular region	Cellular component	-
CTGF	1490	connective tissue growth factor	response to amino acid	Biological process	-
CRHBP	1393	corticotropin releasing hormone binding protein	regulation of corticotropin secretion	Biological process	13150566
CACNA1A	773	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	integral component of membrane	Cellular component	16595610
MEGF8	1954	multiple EGF-like-domains 8	calcium ion binding	Molecular function	-
TRPM4	54795	transient receptor potential cation channel, subfamily M, member 4	Golgi apparatus	Cellular component	19945433
CEBPA	1050	CCAAT/enhancer binding protein (C/EBP), alpha	liver development	Biological process	-
BPI	671	bactericidal/permeability-increasing protein	extracellular exosome	Cellular component	19056867
OCLN	100506658	occludin	cytosol	Cellular component	-
HNRNPA2B1	3181	heterogeneous nuclear ribonucleoprotein A2/B1	mRNA processing	Biological process	2557628
MEIOB	254528	meiosis specific with OB domains	double-strand break repair via homologous recombination	Biological process	-
FFAR3	2865	free fatty acid receptor 3	positive regulation of glucose import in response to insulin stimulus	Biological process	-
ZC3H12B	340554	zinc finger CCCH-type containing 12B	nucleic acid phosphodiester bond hydrolysis	Biological process	-
MDFIC	29969	MyoD family inhibitor domain containing	negative regulation of transcription, DNA-templated	Biological process	-
DEFB132	400830	defensin, beta 132	extracellular region	Cellular component	-
HDAC7	51564	histone deacetylase 7	positive regulation of cell migration involved in sprouting angiogenesis	Biological process	19351956
PDPK1	5170	3-phosphoinositide dependent protein kinase 1	intracellular signal transduction	Biological process	14749367
EAF2	55840	ELL associated factor 2	RNA polymerase II regulatory region sequence-specific DNA binding	Molecular function	16114057
CFB	629	complement factor B	plasma membrane	Cellular component	-
NOTCH4	4855	notch 4	cell fate determination	Biological process	11823422
HRH1	3269	histamine receptor H1	cellular response to histamine	Biological process	-
CYP1A1	1543	cytochrome P450, family 1, subfamily A, polypeptide 1	response to hyperoxia	Biological process	-
TRIM15	89870	tripartite motif containing 15	protein binding	Molecular function	25416956
RAD17	5884	RAD17 homolog (S. pombe)	Rad17 RFC-like complex	Cellular component	-
VAMP5	10791	vesicle-associated membrane protein 5	integral component of plasma membrane	Cellular component	-
ANK3	288	ankyrin 3, node of Ranvier (ankyrin G)	postsynaptic membrane	Cellular component	-
SMAD2	4087	SMAD family member 2	SMAD protein signal transduction	Biological process	-
ACAA1	30	acetyl-CoA acyltransferase 1	fatty acid beta-oxidation	Biological process	2365812
CLGN	1047	calmegin	integral component of membrane	Cellular component	-
EPS15	2060	epidermal growth factor receptor pathway substrate 15	plasma membrane	Cellular component	15465819
ALOX12	239	arachidonate 12-lipoxygenase	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	-
CHRM3	1131	cholinergic receptor, muscarinic 3	axon terminus	Cellular component	-
CCNC	892	cyclin C	regulation of cyclin-dependent protein serine/threonine kinase activity	Biological process	-
SOX17	64321	SRY (sex determining region Y)-box 17	cell migration involved in gastrulation	Biological process	-
KIF18A	81930	kinesin family member 18A	tubulin-dependent ATPase activity	Molecular function	17346968
PAK2	5062	p21 protein (Cdc42/Rac)-activated kinase 2	protein serine/threonine kinase activity	Molecular function	-
THTPA	79178	thiamine triphosphatase	cytosol	Cellular component	-
C5	727	complement component 5	extracellular region	Cellular component	-
CENPA	1058	centromere protein A	condensed nuclear chromosome, centromeric region	Cellular component	11682612
MIER1	57708	mesoderm induction early response 1, transcriptional regulator	chromatin binding	Molecular function	-
MPPED1	758	metallophosphoesterase domain containing 1	hydrolase activity	Molecular function	-
NDP	4693	Norrie disease (pseudoglioma)	extracellular matrix-cell signaling	Biological process	-
PIK3C3	5289	phosphatidylinositol 3-kinase, catalytic subunit type 3	late endosome	Cellular component	14617358
RNF139	11236	ring finger protein 139	receptor activity	Molecular function	9689122
AQP11	282679	aquaporin 11	cytosol	Cellular component	-
SLIT2	9353	slit homolog 2 (Drosophila)	induction of negative chemotaxis	Biological process	10197527
POP4	10775	processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)	ribonuclease P complex	Cellular component	-
CD109	135228	CD109 molecule	negative regulation of protein phosphorylation	Biological process	-
NRAS	4893	neuroblastoma RAS viral (v-ras) oncogene homolog	epidermal growth factor receptor signaling pathway	Biological process	-
BLM	641	Bloom syndrome, RecQ helicase-like	protein oligomerization	Biological process	10359700
AXIN2	8313	axin 2	cytosol	Cellular component	-
ERCC2	2068	excision repair cross-complementation group 2	gene expression	Biological process	-
PDE1B	5153	phosphodiesterase 1B, calmodulin-dependent	fibroblast growth factor receptor signaling pathway	Biological process	-
FBXL15	79176	F-box and leucine-rich repeat protein 15	G2/M transition of mitotic cell cycle	Biological process	21572392
NLRX1	79671	NLR family member X1	protein binding	Molecular function	21903422
ZNF441	126068	zinc finger protein 441	regulation of transcription, DNA-templated	Biological process	-
ZNF45	7596	zinc finger protein 45	nucleoplasm	Cellular component	-
ECM2	1842	extracellular matrix protein 2, female organ and adipocyte specific	collagen V binding	Molecular function	-
TNFRSF9	3604	tumor necrosis factor receptor superfamily, member 9	receptor activity	Molecular function	-
IRG1	730249	immunoresponsive 1 homolog (mouse)	negative regulation of innate immune response	Biological process	-
TMEM98	26022	transmembrane protein 98	integral component of membrane	Cellular component	-
OCSTAMP	128506	osteoclast stimulatory transmembrane protein	cellular response to tumor necrosis factor	Biological process	-
ZNF343	79175	zinc finger protein 343	regulation of transcription, DNA-templated	Biological process	-
SYT11	23208	synaptotagmin XI	synaptic vesicle	Cellular component	21563316
TTC8	123016	tetratricopeptide repeat domain 8	ciliary basal body	Cellular component	14520415
MATN2	4147	matrilin 2	basement membrane	Cellular component	-
C1QTNF1	114897	C1q and tumor necrosis factor related protein 1	protein heterotrimerization	Biological process	-
ZNF283	284349	zinc finger protein 283	sequence-specific DNA binding transcription factor activity	Molecular function	-
ADK	132	adenosine kinase	purine nucleobase metabolic process	Biological process	-
PAPD5	64282	PAP associated domain containing 5	cell division	Biological process	-
ZNF148	7707	zinc finger protein 148	negative regulation of transcription from RNA polymerase II promoter	Biological process	12771217
RNASEH2A	10535	ribonuclease H2, subunit A	RNA phosphodiester bond hydrolysis	Biological process	9789007
DOCK10	55619	dedicator of cytokinesis 10	small GTPase mediated signal transduction	Biological process	-
HIST1H4H	8365	histone cluster 1, H4h	extracellular exosome	Cellular component	19199708
TXN	7295	thioredoxin	movement of cell or subcellular component	Biological process	10947064
LIMK1	3984	LIM domain kinase 1	protein heterodimerization activity	Molecular function	-
UBE2D1	7321	ubiquitin-conjugating enzyme E2D 1	protein complex	Cellular component	22797923
ZNF519	162655	zinc finger protein 519	DNA binding	Molecular function	-
PIK3C3	5289	phosphatidylinositol 3-kinase, catalytic subunit type 3	insulin receptor signaling pathway	Biological process	-
DHRS9	10170	dehydrogenase/reductase (SDR family) member 9	progesterone metabolic process	Biological process	11294878
GRIN2C	2905	glutamate receptor, ionotropic, N-methyl D-aspartate 2C	neuromuscular process controlling balance	Biological process	-
CD244	51744	CD244 molecule, natural killer cell receptor 2B4	plasma membrane	Cellular component	-
LMTK2	22853	lemur tyrosine kinase 2	protein serine/threonine kinase activity	Molecular function	12393858
HSD17B4	3295	hydroxysteroid (17-beta) dehydrogenase 4	17-beta-hydroxysteroid dehydrogenase (NAD+) activity	Molecular function	7487879
PSRC1	84722	proline/serine-rich coiled-coil 1	spindle pole	Cellular component	18411309
C14orf1	11161	chromosome 14 open reading frame 1	sterol biosynthetic process	Biological process	-
ACAN	176	aggrecan	protein binding	Molecular function	17588949
NOP58	51602	NOP58 ribonucleoprotein	pre-snoRNP complex	Cellular component	17636026
OSR1	130497	odd-skipped related transciption factor 1	ureter urothelium development	Biological process	-
APOBEC4	403314	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	Molecular function	-
USP17L11	100287178	ubiquitin specific peptidase 17-like family member 11	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological process	-
MLX	6945	MLX, MAX dimerization protein	protein binding	Molecular function	16189514
POLA2	23649	polymerase (DNA directed), alpha 2, accessory subunit	DNA biosynthetic process	Biological process	-
IQGAP1	8826	IQ motif containing GTPase activating protein 1	small molecule metabolic process	Biological process	-
C12orf10	60314	chromosome 12 open reading frame 10	pigmentation	Biological process	16996721
ZFYVE26	23503	zinc finger, FYVE domain containing 26	cytokinesis	Biological process	20208530
AAGAB	79719	alpha- and gamma-adaptin binding protein	protein transport	Biological process	-
DEFB134	613211	defensin, beta 134	innate immune response	Biological process	-
FRS2	10818	fibroblast growth factor receptor substrate 2	epidermal growth factor receptor signaling pathway	Biological process	-
ACOT4	122970	acyl-CoA thioesterase 4	acyl-CoA hydrolase activity	Molecular function	16141203
SUPT5H	6829	suppressor of Ty 5 homolog (S. cerevisiae)	gene expression	Biological process	-
MRPL21	219927	mitochondrial ribosomal protein L21	structural constituent of ribosome	Molecular function	-
CCL21	6366	chemokine (C-C motif) ligand 21	cell chemotaxis	Biological process	18308860
AGPS	8540	alkylglycerone phosphate synthase	FAD binding	Molecular function	-
CYFIP1	23191	cytoplasmic FMR1 interacting protein 1	lamellipodium	Cellular component	-
MDM2	4193	MDM2 proto-oncogene, E3 ubiquitin protein ligase	cellular response to UV-C	Biological process	-
C14orf169	79697	chromosome 14 open reading frame 169	protein binding	Molecular function	19927124
MX2	4600	MX dynamin-like GTPase 2	cytokine-mediated signaling pathway	Biological process	-
NAB1	4664	NGFI-A binding protein 1 (EGR1 binding protein 1)	Schwann cell differentiation	Biological process	-
GNG2	54331	guanine nucleotide binding protein (G protein), gamma 2	energy reserve metabolic process	Biological process	-
ZNF217	7764	zinc finger protein 217	transcription, DNA-templated	Biological process	-
PARD6G	84552	par-6 family cell polarity regulator gamma	cell junction assembly	Biological process	-
FNIP1	96459	folliculin interacting protein 1	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	-
PTF1A	256297	pancreas specific transcription factor, 1a	endocrine pancreas development	Biological process	-
PLD1	5337	phospholipase D1, phosphatidylcholine-specific	defense response to Gram-positive bacterium	Biological process	-
HRASLS5	117245	HRAS-like suppressor family, member 5	protein binding	Molecular function	25416956
CDH3	1001	cadherin 3, type 1, P-cadherin (placental)	negative regulation of catagen	Biological process	22696062
ABCC9	10060	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	potassium channel regulator activity	Molecular function	-
MYDGF	56005	myeloid-derived growth factor	extracellular space	Cellular component	25581518
E2F7	144455	E2F transcription factor 7	positive regulation of transcription from RNA polymerase II promoter	Biological process	22903062
ASAP3	55616	ArfGAP with SH3 domain, ankyrin repeat and PH domain 3	protein binding	Molecular function	25416956
AGPAT5	55326	1-acylglycerol-3-phosphate O-acyltransferase 5	nuclear envelope	Cellular component	-
LIN28B	389421	lin-28 homolog B (C. elegans)	mitochondrion	Cellular component	-
CHRM4	1132	cholinergic receptor, muscarinic 4	regulation of locomotion	Biological process	-
RPS6KA5	9252	ribosomal protein S6 kinase, 90kDa, polypeptide 5	positive regulation of CREB transcription factor activity	Biological process	18508628
OR5AS1	219447	olfactory receptor, family 5, subfamily AS, member 1	odorant binding	Molecular function	-
MTPAP	55149	mitochondrial poly(A) polymerase	identical protein binding	Molecular function	21292163
SEC31B	25956	SEC31 homolog B (S. cerevisiae)	protein transport	Biological process	-
NDRG4	65009	NDRG family member 4	positive regulation of neuron projection development	Biological process	-
CLCN3	1182	chloride channel, voltage-sensitive 3	protein binding	Molecular function	12471024
TLR4	7099	toll-like receptor 4	positive regulation of interleukin-1 production	Biological process	-
NOXO1	124056	NADPH oxidase organizer 1	regulation of respiratory burst	Biological process	16636067
EIF2AK1	27102	eukaryotic translation initiation factor 2-alpha kinase 1	negative regulation of hemoglobin biosynthetic process	Biological process	-
OR10G8	219869	olfactory receptor, family 10, subfamily G, member 8	G-protein coupled receptor signaling pathway	Biological process	-
ZSCAN10	84891	zinc finger and SCAN domain containing 10	negative regulation of transcription, DNA-templated	Biological process	-
HCFC1R1	54985	host cell factor C1 regulator 1 (XPO1 dependent)	cytoplasm	Cellular component	-
SLC7A1	6541	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1	arginine transmembrane transporter activity	Molecular function	-
ADGRL1	22859	adhesion G protein-coupled receptor L1	synapse	Cellular component	-
PLK2	10769	polo-like kinase 2	protein complex binding	Molecular function	-
SLC25A13	10165	solute carrier family 25 (aspartate/glutamate carrier), member 13	glucose metabolic process	Biological process	-
SLC25A47	283600	solute carrier family 25, member 47	mitochondrial inner membrane	Cellular component	-
NKX2-3	159296	NK2 homeobox 3	biological_process	Biological process	-
NUP62	23636	nucleoporin 62kDa	transmembrane transport	Biological process	-
A4GALT	53947	alpha 1,4-galactosyltransferase	toxic substance binding	Molecular function	-
PSMG1	8624	proteasome (prosome, macropain) assembly chaperone 1	proteasome binding	Molecular function	-
CDC42	998	cell division cycle 42	positive regulation of synapse structural plasticity	Biological process	-
IGFBP6	3489	insulin-like growth factor binding protein 6	extracellular region	Cellular component	-
FOXP2	93986	forkhead box P2	smooth muscle tissue development	Biological process	-
TDRD6	221400	tudor domain containing 6	spermatogenesis	Biological process	-
PTF1A	256297	pancreas specific transcription factor, 1a	retinoic acid receptor signaling pathway	Biological process	-
THBS2	7058	thrombospondin 2	platelet alpha granule	Cellular component	1737102
NTHL1	4913	nth endonuclease III-like 1 (E. coli)	DNA-(apurinic or apyrimidinic site) lyase activity	Molecular function	8990169
TRIO	7204	trio Rho guanine nucleotide exchange factor	protein serine/threonine kinase activity	Molecular function	-
ALOX5	240	arachidonate 5-lipoxygenase	leukotriene biosynthetic process	Biological process	21233389
COL14A1	7373	collagen, type XIV, alpha 1	extracellular matrix organization	Biological process	-
RHPN1	114822	rhophilin, Rho GTPase binding protein 1	small GTPase mediated signal transduction	Biological process	-
NFYA	4800	nuclear transcription factor Y, alpha	protein binding	Molecular function	10571058
GNPTG	84572	N-acetylglucosamine-1-phosphate transferase, gamma subunit	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity	Molecular function	-
YWHAZ	7534	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta	postsynaptic density	Cellular component	-
APH1A	51107	APH1A gamma secretase subunit	membrane	Cellular component	19946888
SLC25A12	8604	solute carrier family 25 (aspartate/glutamate carrier), member 12	L-aspartate transmembrane transport	Biological process	11566871
YME1L1	10730	YME1-like 1 ATPase	metalloendopeptidase activity	Molecular function	-
EEA1	8411	early endosome antigen 1	vesicle fusion	Biological process	9697774
TPGS1	91978	tubulin polyglutamylase complex subunit 1	tubulin-glutamic acid ligase activity	Molecular function	-
SGSH	6448	N-sulfoglucosamine sulfohydrolase	glycosaminoglycan catabolic process	Biological process	-
TEK	7010	TEK tyrosine kinase, endothelial	positive regulation of phosphatidylinositol 3-kinase signaling	Biological process	12816861
GLI2	2736	GLI family zinc finger 2	smoothened signaling pathway involved in ventral spinal cord interneuron specification	Biological process	-
LOR	4014	loricrin	structural molecule activity	Molecular function	10908733
SULT2B1	6820	sulfotransferase family, cytosolic, 2B, member 1	cytoplasm	Cellular component	-
ENAM	10117	enamelin	proteinaceous extracellular matrix	Cellular component	-
ZNF552	79818	zinc finger protein 552	DNA binding	Molecular function	-
DSP	1832	desmoplakin	intermediate filament	Cellular component	16917092
RPS18	6222	ribosomal protein S18	focal adhesion	Cellular component	21423176
AQP1	358	aquaporin 1 (Colton blood group)	apical part of cell	Cellular component	14675051
QSOX2	169714	quiescin Q6 sulfhydryl oxidase 2	cell redox homeostasis	Biological process	-
VAMP1	6843	vesicle-associated membrane protein 1 (synaptobrevin 1)	specific granule membrane	Cellular component	11391393
OR5AS1	219447	olfactory receptor, family 5, subfamily AS, member 1	G-protein coupled receptor signaling pathway	Biological process	-
VASH1	22846	vasohibin 1	cell cycle arrest	Biological process	-
UBA52	7311	ubiquitin A-52 residue ribosomal protein fusion product 1	MyD88-dependent toll-like receptor signaling pathway	Biological process	-
RAD9A	5883	RAD9 homolog A (S. pombe)	cellular response to ionizing radiation	Biological process	21659603
ODF2	4957	outer dense fiber of sperm tails 2	centrosome	Cellular component	-
APOH	350	apolipoprotein H (beta-2-glycoprotein I)	triglyceride transport	Biological process	7078428
DNAJC10	54431	DnaJ (Hsp40) homolog, subfamily C, member 10	ATPase activator activity	Molecular function	-
VCL	7414	vinculin	extracellular vesicle	Cellular component	24769233
CRCP	27297	CGRP receptor component	innate immune response	Biological process	-
PITX2	5308	paired-like homeodomain 2	positive regulation of myoblast proliferation	Biological process	-
FOXP3	50943	forkhead box P3	histone acetyltransferase binding	Molecular function	17360565
FGFR1	2260	fibroblast growth factor receptor 1	positive regulation of MAP kinase activity	Biological process	18480409
AGAP6	414189	ArfGAP with GTPase domain, ankyrin repeat and PH domain 6	GTPase activator activity	Molecular function	-
ANO6	196527	anoctamin 6	activation of blood coagulation via clotting cascade	Biological process	21107324
GJB2	2706	gap junction protein, beta 2, 26kDa	transport	Biological process	1324944
TCAP	8557	titin-cap	protein binding	Molecular function	10984498
LBP	3929	lipopolysaccharide binding protein	receptor binding	Molecular function	2477488
DAP3	7818	death associated protein 3	mitochondrial ribosome	Cellular component	-
CPT2	1376	carnitine palmitoyltransferase 2	small molecule metabolic process	Biological process	-
ST6GALNAC3	256435	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3	glycosphingolipid metabolic process	Biological process	17123352
METTL3	56339	methyltransferase like 3	mRNA splicing, via spliceosome	Biological process	-
GCKR	2646	glucokinase (hexokinase 4) regulator	nucleoplasm	Cellular component	-
TYRO3	7301	TYRO3 protein tyrosine kinase	phosphatidylinositol 3-kinase binding	Molecular function	10627473
STUB1	10273	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase	endoplasmic reticulum	Cellular component	12150907
TRMT2B	79979	tRNA methyltransferase 2 homolog B (S. cerevisiae)	tRNA processing	Biological process	-
BMP4	652	bone morphogenetic protein 4	epithelial-mesenchymal cell signaling	Biological process	-
LCK	3932	LCK proto-oncogene, Src family tyrosine kinase	hemopoiesis	Biological process	12884910
GBA	2629	glucosidase, beta, acid	skin morphogenesis	Biological process	-
CAB39L	81617	calcium binding protein 39-like	extracellular exosome	Cellular component	23376485
NUGGC	389643	nuclear GTPase, germinal center associated	nucleus	Cellular component	-
CDT1	81620	chromatin licensing and DNA replication factor 1	protein binding	Molecular function	11125146
SLC6A4	6532	solute carrier family 6 (neurotransmitter transporter), member 4	cytosol	Cellular component	19270731
DOCK2	1794	dedicator of cytokinesis 2	membrane	Cellular component	19946888
ITGA6	3655	integrin, alpha 6	external side of plasma membrane	Cellular component	-
FSCN2	25794	fascin actin-bundling protein 2, retinal	actin binding	Molecular function	-
FERMT2	10979	fermitin family member 2	cytoplasm	Cellular component	22699938
FSCN1	6624	fascin actin-bundling protein 1	cell migration	Biological process	20393565
OR6C74	254783	olfactory receptor, family 6, subfamily C, member 74	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
PSMA4	5685	proteasome (prosome, macropain) subunit, alpha type, 4	G1/S transition of mitotic cell cycle	Biological process	-
CCP110	9738	centriolar coiled coil protein 110kDa	mitotic cell cycle	Biological process	-
BRSK1	84446	BR serine/threonine kinase 1	nucleus	Cellular component	15150265
SHROOM2	357	shroom family member 2	filamentous actin	Cellular component	-
OR6N2	81442	olfactory receptor, family 6, subfamily N, member 2	detection of chemical stimulus involved in sensory perception	Biological process	-
KCNN4	3783	potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4	Intermediate conductance calcium-activated potassium channel activity	Molecular function	-
RPS6KB1	6198	ribosomal protein S6 kinase, 70kDa, polypeptide 1	germ cell development	Biological process	-
PRKCH	5583	protein kinase C, eta	platelet activation	Biological process	-
RNH1	6050	ribonuclease/angiogenin inhibitor 1	angiogenin-PRI complex	Cellular component	3470787
NTRK2	4915	neurotrophic tyrosine kinase, receptor, type 2	negative regulation of anoikis	Biological process	-
SATB1	6304	SATB homeobox 1	chromatin binding	Molecular function	-
CMPK2	129607	cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial	dTTP biosynthetic process	Biological process	-
MMP19	4327	matrix metallopeptidase 19	response to hormone	Biological process	-
MEST	4232	mesoderm specific transcript	regulation of lipid storage	Biological process	-
SLC29A1	2030	solute carrier family 29 (equilibrative nucleoside transporter), member 1	sleep	Biological process	-
FNBP1	23048	formin binding protein 1	protein binding	Molecular function	11438682
GALR1	2587	galanin receptor 1	positive regulation of cortisol secretion	Biological process	17982695
DSCC1	79075	DNA replication and sister chromatid cohesion 1	nucleoplasm	Cellular component	16682347
NONO	4841	non-POU domain containing, octamer-binding	RNA splicing	Biological process	-
NIPBL	25836	Nipped-B homolog (Drosophila)	negative regulation of transcription from RNA polymerase II promoter	Biological process	18854353
COL1A2	1278	collagen, type I, alpha 2	cellular response to amino acid stimulus	Biological process	-
NLRP5	126206	NLR family, pyrin domain containing 5	cellular protein complex assembly	Biological process	-
CTDSP1	58190	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1	regulation of transcription from RNA polymerase II promoter	Biological process	12721286
HLA-F	3134	major histocompatibility complex, class I, F	receptor binding	Molecular function	-
CETP	1071	cholesteryl ester transfer protein, plasma	high-density lipoprotein particle remodeling	Biological process	2586614
LANCL1	10314	LanC lantibiotic synthetase component C-like 1 (bacterial)	extracellular exosome	Cellular component	23376485
GTF2H2	2966	general transcription factor IIH, polypeptide 2, 44kDa	negative regulation of gene expression, epigenetic	Biological process	-
PIK3R6	146850	phosphoinositide-3-kinase, regulatory subunit 6	1-phosphatidylinositol-3-kinase regulator activity	Molecular function	-
SMO	6608	smoothened, frizzled class receptor	G-protein coupled receptor activity	Molecular function	-
ARRB1	408	arrestin, beta 1	positive regulation of GTPase activity	Biological process	15611106
PRDM6	93166	PR domain containing 6	neurogenesis	Biological process	-
WFDC2	10406	WAP four-disulfide core domain 2	spermatogenesis	Biological process	1686187
TH	7054	tyrosine hydroxylase	response to corticosterone	Biological process	-
HES1	3280	hes family bHLH transcription factor 1	labyrinthine layer blood vessel development	Biological process	-
SPAG9	9043	sperm associated antigen 9	acrosomal vesicle	Cellular component	-
MYO10	4651	myosin X	ruffle	Cellular component	-
FSHR	2492	follicle stimulating hormone receptor	plasma membrane	Cellular component	-
TFF2	7032	trefoil factor 2	positive regulation of cell proliferation	Biological process	-
PLAUR	5329	plasminogen activator, urokinase receptor	blood coagulation	Biological process	-
MCIDAS	345643	multiciliate differentiation and DNA synthesis associated cell cycle protein	transcription, DNA-templated	Biological process	-
VWCE	220001	von Willebrand factor C and EGF domains	positive regulation of cell proliferation	Biological process	-
CYP7A1	1581	cytochrome P450, family 7, subfamily A, polypeptide 1	iron ion binding	Molecular function	-
PTGES3	10728	prostaglandin E synthase 3 (cytosolic)	chaperone cofactor-dependent protein refolding	Biological process	12853476
SCN3B	55800	sodium channel, voltage gated, type III beta subunit	cardiac muscle cell action potential involved in contraction	Biological process	21051419
YY1	7528	YY1 transcription factor	transcription coactivator activity	Molecular function	1946405
ZNF878	729747	zinc finger protein 878	nucleic acid binding	Molecular function	-
EVC	2121	Ellis van Creveld protein	ciliary membrane	Cellular component	-
MGST1	4257	microsomal glutathione S-transferase 1	response to lipopolysaccharide	Biological process	-
CLIC2	1193	chloride intracellular channel 2	glutathione peroxidase activity	Molecular function	15147738
COG4	25839	component of oligomeric golgi complex 4	Golgi membrane	Cellular component	-
ARPC3	10094	actin related protein 2/3 complex, subunit 3, 21kDa	structural constituent of cytoskeleton	Molecular function	11741539
NCKAP1	10787	NCK-associated protein 1	Rac GTPase binding	Molecular function	21107423
C17orf49	124944	chromosome 17 open reading frame 49	MLL1 complex	Cellular component	15960975
EPHX1	2052	epoxide hydrolase 1, microsomal (xenobiotic)	response to toxic substance	Biological process	-
KDM5A	5927	lysine (K)-specific demethylase 5A	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors	Molecular function	-
CAMK2D	817	calcium/calmodulin-dependent protein kinase II delta	peptidyl-threonine phosphorylation	Biological process	22514276
TNF	7124	tumor necrosis factor	extracellular matrix organization	Biological process	-
MLLT3	4300	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3	segment specification	Biological process	-
CDO1	1036	cysteine dioxygenase type 1	lactation	Biological process	-
SNIP1	79753	Smad nuclear interacting protein 1	regulation of transcription, DNA-templated	Biological process	-
HIST1H4A	8359	histone cluster 1, H4a	regulation of gene expression, epigenetic	Biological process	-
CLCN6	1185	chloride channel, voltage-sensitive 6	regulation of anion transmembrane transport	Biological process	8543009
AVEN	57099	apoptosis, caspase activation inhibitor	intracellular	Cellular component	10949025
CCNI	10983	cyclin I	spermatogenesis	Biological process	9705831
NR2C2	7182	nuclear receptor subfamily 2, group C, member 2	steroid hormone receptor activity	Molecular function	-
F2RL1	2150	coagulation factor II (thrombin) receptor-like 1	positive regulation of actin filament depolymerization	Biological process	17500066
GNG2	54331	guanine nucleotide binding protein (G protein), gamma 2	blood coagulation	Biological process	-
AQP1	358	aquaporin 1 (Colton blood group)	small molecule metabolic process	Biological process	-
MSH2	4436	mutS homolog 2	maintenance of DNA repeat elements	Biological process	16388310
FGFRL1	53834	fibroblast growth factor receptor-like 1	cell-cell adhesion via plasma-membrane adhesion molecules	Biological process	18061161
MAPK7	5598	mitogen-activated protein kinase 7	mitogen-activated protein kinase binding	Molecular function	23043106
NGF	4803	nerve growth factor (beta polypeptide)	positive regulation of neurotrophin TRK receptor signaling pathway	Biological process	-
XPNPEP3	63929	X-prolyl aminopeptidase 3, mitochondrial	metallopeptidase activity	Molecular function	-
MSRA	4482	methionine sulfoxide reductase A	mitochondrion	Cellular component	-
STMN1	3925	stathmin 1	negative regulation of microtubule polymerization	Biological process	-
CCDC9	26093	coiled-coil domain containing 9	poly(A) RNA binding	Molecular function	22658674
SOX9	6662	SRY (sex determining region Y)-box 9	cartilage condensation	Biological process	-
INTS9	55756	integrator complex subunit 9	snRNA processing	Biological process	16239144
EDN1	1906	endothelin 1	protein kinase C deactivation	Biological process	16820593
ZNF100	163227	zinc finger protein 100	regulation of transcription, DNA-templated	Biological process	-
SLC1A6	6511	solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6	integral component of plasma membrane	Cellular component	7791878
PTGR1	22949	prostaglandin reductase 1	zinc ion binding	Molecular function	-
SLA2	84174	Src-like-adaptor 2	regulation of immune response	Biological process	11696592
CHD1L	9557	chromodomain helicase DNA binding protein 1-like	DNA duplex unwinding	Biological process	19661379
HMGB3	3149	high mobility group box 3	DNA binding, bending	Molecular function	-
CYGB	114757	cytoglobin	protein binding	Molecular function	25416956
TAF1	6872	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa	peptidyl-serine phosphorylation	Biological process	8625415
BAD	572	BCL2-associated agonist of cell death	extrinsic apoptotic signaling pathway via death domain receptors	Biological process	-
LIF	3976	leukemia inhibitory factor	positive regulation of astrocyte differentiation	Biological process	-
MPHOSPH8	54737	M-phase phosphoprotein 8	nucleolus	Cellular component	-
PSEN2	5664	presenilin 2	cell cortex	Cellular component	-
MYB	4602	v-myb avian myeloblastosis viral oncogene homolog	chromatin binding	Molecular function	-
CARD9	64170	caspase recruitment domain family, member 9	response to exogenous dsRNA	Biological process	-
TAGAP	117289	T-cell activation RhoGTPase activating protein	guanyl-nucleotide exchange factor activity	Molecular function	-
RAF1	5894	Raf-1 proto-oncogene, serine/threonine kinase	small GTPase binding	Molecular function	12194967
SLC39A6	25800	solute carrier family 39 (zinc transporter), member 6	transmembrane transport	Biological process	-
TMEM109	79073	transmembrane protein 109	extracellular exosome	Cellular component	19199708
PPP2CB	5516	protein phosphatase 2, catalytic subunit, beta isozyme	protein phosphatase type 2A complex	Cellular component	8206937
HS3ST2	9956	heparan sulfate (glucosamine) 3-O-sulfotransferase 2	integral component of membrane	Cellular component	-
DMP1	1758	dentin matrix acidic phosphoprotein 1	nucleolus	Cellular component	-
ATG7	10533	autophagy related 7	macroautophagy	Biological process	-
PITPNB	23760	phosphatidylinositol transfer protein, beta	lipid metabolic process	Biological process	8541325
LMO4	8543	LIM domain only 4	neural tube closure	Biological process	-
PEX11B	8799	peroxisomal biogenesis factor 11 beta	extracellular exosome	Cellular component	23376485
BLOC1S6	26258	biogenesis of lysosomal organelles complex-1, subunit 6, pallidin	extrinsic component of membrane	Cellular component	12019270
RPTOR	57521	regulatory associated protein of MTOR, complex 1	positive regulation of transcription from RNA polymerase III promoter	Biological process	20233713
NR2F2	7026	nuclear receptor subfamily 2, group F, member 2	blood vessel morphogenesis	Biological process	-
VAMP2	6844	vesicle-associated membrane protein 2 (synaptobrevin 2)	SNAP receptor activity	Molecular function	-
FUT7	2529	fucosyltransferase 7 (alpha (1,3) fucosyltransferase)	fucosylation	Biological process	11698403
DNM1L	10059	dynamin 1-like	positive regulation of apoptotic process	Biological process	20850011
MAP1LC3A	84557	microtubule-associated protein 1 light chain 3 alpha	protein binding	Molecular function	11096062
NPHS1	4868	nephrosis 1, congenital, Finnish type (nephrin)	myosin binding	Molecular function	21402783
IMP3	55272	IMP3, U3 small nucleolar ribonucleoprotein	nucleus	Cellular component	-
EVI5	7813	ecotropic viral integration site 5	spindle	Cellular component	-
CASP1	834	caspase 1, apoptosis-related cysteine peptidase	programmed necrotic cell death	Biological process	-
KCNG4	93107	potassium channel, voltage gated modifier subfamily G, member 4	plasma membrane	Cellular component	-
HSH2D	84941	hematopoietic SH2 domain containing	negative regulation of mitochondrial depolarization	Biological process	-
RPL19	6143	ribosomal protein L19	gene expression	Biological process	-
ZCCHC6	79670	zinc finger, CCHC domain containing 6	RNA uridylyltransferase activity	Molecular function	17353264
SLC5A1	6523	solute carrier family 5 (sodium/glucose cotransporter), member 1	integral component of plasma membrane	Cellular component	8563765
MTM1	4534	myotubularin 1	cytosol	Cellular component	-
MRPS24	64951	mitochondrial ribosomal protein S24	mitochondrial translational initiation	Biological process	-
NFKB2	4791	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	sequence-specific DNA binding transcription factor activity	Molecular function	1760839
GFPT1	2673	glutamine--fructose-6-phosphate transaminase 1	dolichol-linked oligosaccharide biosynthetic process	Biological process	-
EHD4	30844	EH-domain containing 4	positive regulation of peptidyl-tyrosine phosphorylation	Biological process	-
FZR1	51343	fizzy/cell division cycle 20 related 1 (Drosophila)	mitotic nuclear division	Biological process	-
PROX1	5629	prospero homeobox 1	venous blood vessel morphogenesis	Biological process	-
RAB8B	51762	RAB8B, member RAS oncogene family	plasma membrane	Cellular component	-
HLX	3142	H2.0-like homeobox	regulation of transcription, DNA-templated	Biological process	-
MAPK8	5599	mitogen-activated protein kinase 8	MyD88-independent toll-like receptor signaling pathway	Biological process	-
RAB7A	7879	RAB7A, member RAS oncogene family	phagosome acidification	Biological process	21255211
B3GALNT2	148789	beta-1,3-N-acetylgalactosaminyltransferase 2	endoplasmic reticulum	Cellular component	23453667
WNK2	65268	WNK lysine deficient protein kinase 2	intracellular signal transduction	Biological process	-
GSTM2	2946	glutathione S-transferase mu 2 (muscle)	glutathione transferase activity	Molecular function	16549767
GCK	2645	glucokinase (hexokinase 4)	glycolytic process	Biological process	-
NLGN1	22871	neuroligin 1	synapse assembly	Biological process	-
DPM2	8818	dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit	enzyme regulator activity	Molecular function	-
SH3D19	152503	SH3 domain containing 19	nucleoplasm	Cellular component	-
IRF1	3659	interferon regulatory factor 1	regulation of cell cycle	Biological process	11846974
IFT57	55081	intraflagellar transport 57	organelle organization	Biological process	-
BCL2L11	10018	BCL2-like 11 (apoptosis facilitator)	positive regulation of apoptotic process	Biological process	-
SIRT3	23410	sirtuin 3	peptidyl-lysine deacetylation	Biological process	22309213
RPL32	6161	ribosomal protein L32	centrosome	Cellular component	-
VIPR2	7434	vasoactive intestinal peptide receptor 2	plasma membrane	Cellular component	-
PRKAR2B	5577	protein kinase, cAMP-dependent, regulatory, type II, beta	epidermal growth factor receptor signaling pathway	Biological process	-
CEACAM5	1048	carcinoembryonic antigen-related cell adhesion molecule 5	anchored component of membrane	Cellular component	-
GATA5	140628	GATA binding protein 5	transcription from RNA polymerase II promoter	Biological process	-
THEMIS2	9473	thymocyte selection associated family member 2	protein binding	Molecular function	25416956
AKAP8L	26993	A kinase (PRKA) anchor protein 8-like	cytoplasm	Cellular component	-
CASP6	839	caspase 6, apoptosis-related cysteine peptidase	epithelial cell differentiation	Biological process	21492153
FBXL15	79176	F-box and leucine-rich repeat protein 15	bone mineralization	Biological process	-
ST13	6767	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	extracellular exosome	Cellular component	19056867
ANXA9	8416	annexin A9	protein homodimerization activity	Molecular function	10899159
UGT1A3	54659	UDP glucuronosyltransferase 1 family, polypeptide A3	negative regulation of cellular glucuronidation	Biological process	20610558
LMX1A	4009	LIM homeobox transcription factor 1, alpha	negative regulation of neuron differentiation	Biological process	-
RARA	5914	retinoic acid receptor, alpha	positive regulation of binding	Biological process	20080953
NUCB2	4925	nucleobindin 2	Golgi apparatus	Cellular component	-
SPARC	6678	secreted protein, acidic, cysteine-rich (osteonectin)	extracellular matrix binding	Molecular function	-
RAC2	5880	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	G-protein coupled receptor signaling pathway	Biological process	-
COL4A3	1285	collagen, type IV, alpha 3 (Goodpasture antigen)	extracellular matrix disassembly	Biological process	-
ZNF75A	7627	zinc finger protein 75a	DNA binding	Molecular function	-
HADH	3033	hydroxyacyl-CoA dehydrogenase	mitochondrial matrix	Cellular component	-
REN	5972	renin	proteolysis	Biological process	12045255
SLC8A1	6546	solute carrier family 8 (sodium/calcium exchanger), member 1	heart morphogenesis	Biological process	-
RSL1D1	26156	ribosomal L1 domain containing 1	regulation of cellular senescence	Biological process	18678645
NSUN7	79730	NOP2/Sun domain family, member 7	methyltransferase activity	Molecular function	-
LYG2	254773	lysozyme G-like 2	lysozyme activity	Molecular function	-
DLG4	1742	discs, large homolog 4 (Drosophila)	juxtaparanode region of axon	Cellular component	-
SHPRH	257218	SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase	helicase activity	Molecular function	-
VTA1	51534	vesicle (multivesicular body) trafficking 1	multivesicular body sorting pathway	Biological process	15644320
SOX9	6662	SRY (sex determining region Y)-box 9	cAMP-mediated signaling	Biological process	10805756
HTR5A	3361	5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled	integral component of plasma membrane	Cellular component	-
EIF2AK3	9451	eukaryotic translation initiation factor 2-alpha kinase 3	negative regulation of myelination	Biological process	-
RNF34	80196	ring finger protein 34, E3 ubiquitin protein ligase	cellular response to cold	Biological process	-
SGK3	23678	serum/glucocorticoid regulated kinase family, member 3	potassium channel regulator activity	Molecular function	16460280
MVD	4597	mevalonate (diphospho) decarboxylase	dolichyl diphosphate biosynthetic process	Biological process	-
SLC39A13	91252	solute carrier family 39 (zinc transporter), member 13	Golgi apparatus	Cellular component	18985159
CBX5	23468	chromobox homolog 5	nucleolus	Cellular component	9636146
OR4C16	219428	olfactory receptor, family 4, subfamily C, member 16 (gene/pseudogene)	G-protein coupled receptor activity	Molecular function	-
ACOX3	8310	acyl-CoA oxidase 3, pristanoyl	membrane	Cellular component	19946888
ZNF622	90441	zinc finger protein 622	positive regulation of kinase activity	Biological process	21771788
ILF3	3609	interleukin enhancer binding factor 3, 90kDa	protein binding	Molecular function	10574923
CHD7	55636	chromodomain helicase DNA binding protein 7	T cell differentiation	Biological process	17684005
OPRK1	4986	opioid receptor, kappa 1	defense response to virus	Biological process	8755601
EGLN3	112399	egl-9 family hypoxia-inducible factor 3	protein hydroxylation	Biological process	19584355
MYO1F	4542	myosin IF	filamentous actin	Cellular component	-
CCNY	219771	cyclin Y	extracellular exosome	Cellular component	23376485
SGPP2	130367	sphingosine-1-phosphate phosphatase 2	sphingolipid metabolic process	Biological process	-
CALR	811	calreticulin	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	Biological process	-
SLC26A2	1836	solute carrier family 26 (anion exchanger), member 2	secondary active sulfate transmembrane transporter activity	Molecular function	-
SFT2D2	375035	SFT2 domain containing 2	integral component of membrane	Cellular component	-
APOA1	335	apolipoprotein A-I	organ regeneration	Biological process	-
USP40	55230	ubiquitin specific peptidase 40	cytoplasm	Cellular component	-
PRDM8	56978	PR domain containing 8	histone methyltransferase activity (H3-K9 specific)	Molecular function	-
PARVA	55742	parvin, alpha	actin cytoskeleton	Cellular component	-
UNC13D	201294	unc-13 homolog D (C. elegans)	Rab GTPase binding	Molecular function	22899725
HDAC6	10013	histone deacetylase 6	caveola	Cellular component	18356165
RANBP2	5903	RAN binding protein 2	gene expression	Biological process	-
SETD7	80854	SET domain containing (lysine methyltransferase) 7	peptidyl-lysine monomethylation	Biological process	17108971
SIGIRR	59307	single immunoglobulin and toll-interleukin 1 receptor (TIR) domain	protein binding	Molecular function	12925853
YWHAE	7531	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon	viral process	Biological process	-
FHL2	2274	four and a half LIM domains 2	small molecule metabolic process	Biological process	-
IL15RA	3601	interleukin 15 receptor, alpha	integral component of membrane	Cellular component	-
IRX3	79191	iroquois homeobox 3	negative regulation of neuron differentiation	Biological process	-
SIRPA	140885	signal-regulatory protein alpha	membrane	Cellular component	9062191
IGHA1	3493	immunoglobulin heavy constant alpha 1	antibacterial humoral response	Biological process	23250751
TGFBR2	7048	transforming growth factor, beta receptor II (70/80kDa)	transforming growth factor beta receptor activity, type II	Molecular function	-
CIB1	10519	calcium and integrin binding 1 (calmyrin)	growth cone	Cellular component	21215777
ST14	6768	suppression of tumorigenicity 14 (colon carcinoma)	plasma membrane	Cellular component	10373424
PAPPA2	60676	pappalysin 2	bone morphogenesis	Biological process	-
MKNK1	8569	MAP kinase interacting serine/threonine kinase 1	nucleus	Cellular component	-
PDCD2	5134	programmed cell death 2	protein binding	Molecular function	19146857
CCKBR	887	cholecystokinin B receptor	positive regulation of cell proliferation	Biological process	10913157
RHBG	57127	Rh family, B glycoprotein (gene/pseudogene)	ammonium transmembrane transport	Biological process	-
CDKN2A	1029	cyclin-dependent kinase inhibitor 2A	mitotic cell cycle	Biological process	-
FRS2	10818	fibroblast growth factor receptor substrate 2	optic placode formation involved in camera-type eye formation	Biological process	-
TMCO6	55374	transmembrane and coiled-coil domains 6	integral component of membrane	Cellular component	-
TAF1L	138474	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like	transcription initiation from RNA polymerase II promoter	Biological process	-
EIF2A	83939	eukaryotic translation initiation factor 2A, 65kDa	extracellular space	Cellular component	22664934
CXCL10	3627	chemokine (C-X-C motif) ligand 10	cellular response to lipopolysaccharide	Biological process	23776175
CBX3	11335	chromobox homolog 3	chromosome, centromeric region	Cellular component	10504293
TROVE2	6738	TROVE domain family, member 2	RNA binding	Molecular function	3200833
AMBP	259	alpha-1-microglobulin/bikunin precursor	receptor-mediated endocytosis	Biological process	-
HACD4	401494	3-hydroxyacyl-CoA dehydratase 4	endoplasmic reticulum membrane	Cellular component	-
DDOST	1650	dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)	protein N-linked glycosylation	Biological process	9642163
SLC5A10	125206	solute carrier family 5 (sodium/sugar cotransporter), member 10	sodium ion transport	Biological process	-
NCOR1	9611	nuclear receptor corepressor 1	transcription, DNA-templated	Biological process	-
CREBRF	153222	CREB3 regulatory factor	transport	Biological process	-
LYN	4067	LYN proto-oncogene, Src family tyrosine kinase	ion channel binding	Molecular function	12538589
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	negative regulation of mitotic cell cycle, embryonic	Biological process	-
NCK2	8440	NCK adaptor protein 2	negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation	Biological process	16835242
MLLT3	4300	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3	regulation of transcription, DNA-templated	Biological process	-
ZNF181	339318	zinc finger protein 181	metal ion binding	Molecular function	-
ADM	133	adrenomedullin	positive regulation of vasculogenesis	Biological process	-
PKD2	5311	polycystic kidney disease 2 (autosomal dominant)	metanephric distal tubule development	Biological process	11891195
C4B	721	complement component 4B (Chido blood group)	extracellular region	Cellular component	-
POU3F3	5455	POU class 3 homeobox 3	transcription, DNA-templated	Biological process	-
EMD	2010	emerin	endoplasmic reticulum	Cellular component	-
LIN7A	8825	lin-7 homolog A (C. elegans)	asymmetric protein localization	Biological process	-
MMP14	4323	matrix metallopeptidase 14 (membrane-inserted)	negative regulation of focal adhesion assembly	Biological process	-
TGFBR1	7046	transforming growth factor, beta receptor 1	receptor signaling protein activity	Molecular function	-
AURKB	9212	aurora kinase B	positive regulation of cytokinesis	Biological process	19774610
GGH	8836	gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)	response to ethanol	Biological process	-
ZNF598	90850	zinc finger protein 598	poly(A) RNA binding	Molecular function	22658674
GTF2E1	2960	general transcription factor IIE, polypeptide 1, alpha 56kDa	transcription elongation from RNA polymerase II promoter	Biological process	-
GALK1	2584	galactokinase 1	carbohydrate metabolic process	Biological process	-
NLGN4Y	22829	neuroligin 4, Y-linked	integral component of plasma membrane	Cellular component	-
AKR1C3	8644	aldo-keto reductase family 1, member C3	retinal dehydrogenase activity	Molecular function	21851338
KIT	3815	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	embryonic hemopoiesis	Biological process	-
WDR45	11152	WD repeat domain 45	protein localization to pre-autophagosomal structure	Biological process	-
LRRK2	120892	leucine-rich repeat kinase 2	activation of MAPKK activity	Biological process	19302196
ELAVL1	1994	ELAV like RNA binding protein 1	nucleotide binding	Molecular function	-
SFRP4	6424	secreted frizzled-related protein 4	negative regulation of cell proliferation	Biological process	14760084
TLR8	51311	toll-like receptor 8	microglial cell activation	Biological process	-
NR3C2	4306	nuclear receptor subfamily 3, group C, member 2	endoplasmic reticulum membrane	Cellular component	-
HTR4	3360	5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled	regulation of appetite	Biological process	-
NCOR1	9611	nuclear receptor corepressor 1	histone deacetylase complex	Cellular component	18326024
NOS1AP	9722	nitric oxide synthase 1 (neuronal) adaptor protein	regulation of apoptotic process	Biological process	20431962
SMN2	6607	survival of motor neuron 2, centromeric	nervous system development	Biological process	-
CARF	79800	calcium responsive transcription factor	DNA binding	Molecular function	11832226
CORO1A	11151	coronin, actin binding protein, 1A	extracellular exosome	Cellular component	20458337
MUC12	10071	mucin 12, cell surface associated	post-translational protein modification	Biological process	-
MSTN	2660	myostatin	extracellular space	Cellular component	-
FAM107B	83641	family with sequence similarity 107, member B	sensory perception of sound	Biological process	-
IER3	8870	immediate early response 3	negative regulation of apoptotic process	Biological process	9703517
UEVLD	55293	UEV and lactate/malate dehyrogenase domains	protein transport	Biological process	-
PMF1	11243	polyamine-modulated factor 1	transcription from RNA polymerase II promoter	Biological process	10419538
UPF3B	65109	UPF3 regulator of nonsense transcripts homolog B (yeast)	mRNA 3'-end processing	Biological process	-
TCF20	6942	transcription factor 20 (AR1)	zinc ion binding	Molecular function	-
MYO1E	4643	myosin IE	protein binding	Molecular function	17257598
WNT5A	7474	wingless-type MMTV integration site family, member 5A	cell surface	Cellular component	-
ST13	6767	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	protein binding	Molecular function	21163940
HDGFRP3	50810	hepatoma-derived growth factor, related protein 3	nucleoplasm	Cellular component	-
SCYL3	57147	SCY1-like 3 (S. cerevisiae)	ATP binding	Molecular function	-
GPR61	83873	G protein-coupled receptor 61	biological_process	Biological process	-
PDE3A	5139	phosphodiesterase 3A, cGMP-inhibited	integral component of membrane	Cellular component	-
PTEN	5728	phosphatase and tensin homolog	response to estradiol	Biological process	-
AHI1	54806	Abelson helper integration site 1	positive regulation of polarized epithelial cell differentiation	Biological process	-
ISOC2	79763	isochorismatase domain containing 2	nucleus	Cellular component	17658461
HLA-DRB3	3125	major histocompatibility complex, class II, DR beta 3	inflammatory response to antigenic stimulus	Biological process	15795121
MKS1	54903	Meckel syndrome, type 1	ciliary basal body	Cellular component	19208769
GATA3	2625	GATA binding protein 3	T-helper 2 cell differentiation	Biological process	-
RPL35A	6165	ribosomal protein L35a	translational termination	Biological process	-
GOLGB1	2804	golgin B1	protein binding	Molecular function	14980500
S1PR4	8698	sphingosine-1-phosphate receptor 4	positive regulation of cytosolic calcium ion concentration	Biological process	10679247
DTX1	1840	deltex 1, E3 ubiquitin ligase	cytoplasm	Cellular component	9590294
MGAT2	4247	mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	Golgi apparatus	Cellular component	-
TOE1	114034	target of EGR1, member 1 (nuclear)	protein binding	Molecular function	19508870
SEC11C	90701	SEC11 homolog C (S. cerevisiae)	gene expression	Biological process	-
PCNA	5111	proliferating cell nuclear antigen	cell proliferation	Biological process	2565339
NRXN1	9378	neurexin 1	positive regulation of establishment of protein localization to plasma membrane	Biological process	-
NPVF	64111	neuropeptide VF precursor	neuropeptide signaling pathway	Biological process	11025660
FBXO45	200933	F-box protein 45	neuron migration	Biological process	-
CBS	875	cystathionine-beta-synthase	cystathionine beta-synthase activity	Molecular function	-
CDK6	1021	cyclin-dependent kinase 6	ATP binding	Molecular function	9751050
TRIM36	55521	tripartite motif containing 36	protein ubiquitination	Biological process	-
AMPD3	272	adenosine monophosphate deaminase 3	cytosol	Cellular component	-
NKX2-1	7080	NK2 homeobox 1	intronic transcription regulatory region sequence-specific DNA binding	Molecular function	-
GTF3C5	9328	general transcription factor IIIC, polypeptide 5, 63kDa	DNA binding	Molecular function	17409385
PRMT7	54496	protein arginine methyltransferase 7	protein-arginine omega-N monomethyltransferase activity	Molecular function	15044439
FN1	2335	fibronectin 1	extracellular matrix disassembly	Biological process	-
KIF20B	9585	kinesin family member 20B	ATP binding	Molecular function	-
BECN1	8678	beclin 1, autophagy related	cellular response to glucose starvation	Biological process	-
ZBTB49	166793	zinc finger and BTB domain containing 49	cell cycle arrest	Biological process	25245946
PPP2R5B	5526	protein phosphatase 2, regulatory subunit B', beta	cytoplasm	Cellular component	8703017
TMEM30A	55754	transmembrane protein 30A	transport vesicle membrane	Cellular component	-
KHK	3795	ketohexokinase (fructokinase)	cytoplasm	Cellular component	-
SLC25A15	10166	solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15	mitochondrial ornithine transport	Biological process	10369256
SCAMP4	113178	secretory carrier membrane protein 4	integral component of membrane	Cellular component	-
DNPEP	23549	aspartyl aminopeptidase	peptide metabolic process	Biological process	9632644
PIK3C2A	5286	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha	phosphatidylinositol binding	Molecular function	-
TMEM161A	54929	transmembrane protein 161A	integral component of membrane	Cellular component	-
EPHA1	2041	EPH receptor A1	positive regulation of cell proliferation	Biological process	20043122
CASP9	842	caspase 9, apoptosis-related cysteine peptidase	intrinsic apoptotic signaling pathway	Biological process	-
PDGFRA	5156	platelet-derived growth factor receptor, alpha polypeptide	fibroblast growth factor receptor signaling pathway	Biological process	-
DHFR	1719	dihydrofolate reductase	nucleotide biosynthetic process	Biological process	-
COMMD9	29099	COMM domain containing 9	protein binding	Molecular function	21778237
FCER1G	2207	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	innate immune response	Biological process	-
NUP155	9631	nucleoporin 155kDa	regulation of glucose transport	Biological process	-
ATP13A1	57130	ATPase type 13A1	molecular_function	Molecular function	-
KBTBD7	84078	kelch repeat and BTB (POZ) domain containing 7	protein binding	Molecular function	16169070
DHX32	55760	DEAH (Asp-Glu-Ala-His) box polypeptide 32	protein binding	Molecular function	25416956
NCOA6	23054	nuclear receptor coactivator 6	chromatin binding	Molecular function	-
INPP5J	27124	inositol polyphosphate-5-phosphatase J	cytosol	Cellular component	-
REV3L	5980	REV3-like, polymerase (DNA directed), zeta, catalytic subunit	zeta DNA polymerase complex	Cellular component	20164194
PTGES3	10728	prostaglandin E synthase 3 (cytosolic)	telomere maintenance	Biological process	12135483
TNNI2	7136	troponin I type 2 (skeletal, fast)	nucleus	Cellular component	18331830
SUMO1	7341	small ubiquitin-like modifier 1	nucleoplasm	Cellular component	-
RHBDD1	84236	rhomboid domain containing 1	endoplasmic reticulum quality control compartment	Cellular component	-
TSSK3	81629	testis-specific serine kinase 3	protein phosphorylation	Biological process	-
PAPOLB	56903	poly(A) polymerase beta (testis specific)	mRNA polyadenylation	Biological process	-
CHRNA10	57053	cholinergic receptor, nicotinic, alpha 10 (neuronal)	acetylcholine-gated channel complex	Cellular component	-
HOXC9	3225	homeobox C9	sequence-specific DNA binding	Molecular function	-
CYP4F11	57834	cytochrome P450, family 4, subfamily F, polypeptide 11	inflammatory response	Biological process	10964514
BCL2L2	599	BCL2-like 2	negative regulation of apoptotic process	Biological process	17289999
ZNF483	158399	zinc finger protein 483	DNA binding	Molecular function	-
KIF3B	9371	kinesin family member 3B	intraciliary transport particle	Cellular component	-
APOB	338	apolipoprotein B	triglyceride catabolic process	Biological process	-
RFX2	5990	regulatory factor X, 2 (influences HLA class II expression)	sequence-specific DNA binding transcription factor activity	Molecular function	-
C6orf106	64771	chromosome 6 open reading frame 106	biological_process	Biological process	-
ZIC3	7547	Zic family member 3	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	17764085
PLA2G2A	5320	phospholipase A2, group IIA (platelets, synovial fluid)	extracellular space	Cellular component	17069818
IRAK1	3654	interleukin-1 receptor-associated kinase 1	response to interleukin-1	Biological process	10383454
PSMC5	5705	proteasome (prosome, macropain) 26S subunit, ATPase, 5	proteasome accessory complex	Cellular component	-
CCDC93	54520	coiled-coil domain containing 93	protein binding	Molecular function	25355947
IFIH1	64135	interferon induced with helicase C domain 1	zinc ion binding	Molecular function	19380577
CTHRC1	115908	collagen triple helix repeat containing 1	positive regulation of osteoblast differentiation	Biological process	-
LSG1	55341	large 60S subunit nuclear export GTPase 1	cytoplasm	Cellular component	-
MERTK	10461	MER proto-oncogene, tyrosine kinase	cell-cell signaling	Biological process	8086340
TLR3	7098	toll-like receptor 3	identical protein binding	Molecular function	25217833
PSPH	5723	phosphoserine phosphatase	L-serine biosynthetic process	Biological process	-
WNT8A	7478	wingless-type MMTV integration site family, member 8A	canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment	Biological process	20559569
INTS5	80789	integrator complex subunit 5	integrator complex	Cellular component	16239144
DNAJC5	80331	DnaJ (Hsp40) homolog, subfamily C, member 5	synaptic vesicle	Cellular component	-
HLA-DMB	3109	major histocompatibility complex, class II, DM beta	MHC class II protein complex	Cellular component	22247549
COPB1	1315	coatomer protein complex, subunit beta 1	cytosol	Cellular component	-
NLGN2	57555	neuroligin 2	regulation of synaptic transmission	Biological process	-
GJA9	81025	gap junction protein, alpha 9, 59kDa	connexon complex	Cellular component	-
CLPSL2	389383	colipase-like 2	extracellular region	Cellular component	-
MECOM	2122	MDS1 and EVI1 complex locus	aggresome	Cellular component	-
KCNMB1	3779	potassium channel subfamily M regulatory beta subunit 1	calcium-activated potassium channel activity	Molecular function	-
KCND1	3750	potassium channel, voltage gated Shal related subfamily D, member 1	cellular_component	Cellular component	-
RBPJ	3516	recombination signal binding protein for immunoglobulin kappa J region	negative regulation of ossification	Biological process	-
KIF17	57576	kinesin family member 17	protein transport	Biological process	-
GPIHBP1	338328	glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1	apical plasma membrane	Cellular component	20620994
BDNF	627	brain-derived neurotrophic factor	cellular response to tumor necrosis factor	Biological process	-
OR6C3	254786	olfactory receptor, family 6, subfamily C, member 3	integral component of membrane	Cellular component	10706615
TRIB1	10221	tribbles pseudokinase 1	regulation of MAP kinase activity	Biological process	15299019
ZNF560	147741	zinc finger protein 560	transcription, DNA-templated	Biological process	-
ADAMTS9	56999	ADAM metallopeptidase with thrombospondin type 1 motif, 9	extracellular matrix	Cellular component	22261194
MAP3K15	389840	mitogen-activated protein kinase kinase kinase 15	activation of MAPKK activity	Biological process	-
PKDCC	91461	protein kinase domain containing, cytoplasmic	plasmodesma	Cellular component	-
ATP7B	540	ATPase, Cu++ transporting, beta polypeptide	perinuclear region of cytoplasm	Cellular component	16939419
SRRT	51593	serrate, RNA effector molecule	cell proliferation	Biological process	-
BAK1	578	BCL2-antagonist/killer 1	myeloid cell homeostasis	Biological process	-
HNF4G	3174	hepatocyte nuclear factor 4, gamma	positive regulation of transcription, DNA-templated	Biological process	-
METTL21C	196541	methyltransferase like 21C	nucleus	Cellular component	-
TPRN	286262	taperin	molecular_function	Molecular function	-
ARID4B	51742	AT rich interactive domain 4B (RBP1-like)	histone H4-K20 trimethylation	Biological process	-
NRBP1	29959	nuclear receptor binding protein 1	lamellipodium	Cellular component	-
SCN10A	6336	sodium channel, voltage gated, type X alpha subunit	sensory perception	Biological process	9839820
ALDH1L2	160428	aldehyde dehydrogenase 1 family, member L2	biosynthetic process	Biological process	-
ZNF649	65251	zinc finger protein 649	nucleus	Cellular component	-
KIF1C	10749	kinesin family member 1C	kinesin complex	Cellular component	-
S100A12	6283	S100 calcium binding protein A12	nucleus	Cellular component	15033494
TBXAS1	6916	thromboxane A synthase 1 (platelet)	cyclooxygenase pathway	Biological process	-
EIF4A1	1973	eukaryotic translation initiation factor 4A1	organ regeneration	Biological process	-
P2RX5	5026	purinergic receptor P2X, ligand gated ion channel, 5	response to ATP	Biological process	-
CRMP1	1400	collapsin response mediator protein 1	spindle	Cellular component	-
DNAAF2	55172	dynein, axonemal, assembly factor 2	protein binding	Molecular function	23872636
ICAM1	3383	intercellular adhesion molecule 1	cellular response to lipopolysaccharide	Biological process	-
SNX10	29887	sorting nexin 10	endosome	Cellular component	-
TENM2	57451	teneurin transmembrane protein 2	axon guidance	Biological process	21724987
AXIN2	8313	axin 2	regulation of mismatch repair	Biological process	11017067
CASQ1	844	calsequestrin 1 (fast-twitch, skeletal muscle)	sarcoplasmic reticulum membrane	Cellular component	-
HUWE1	10075	HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase	protein polyubiquitination	Biological process	15989957
CRBN	51185	cereblon	metal ion binding	Molecular function	-
FGF8	2253	fibroblast growth factor 8 (androgen-induced)	forebrain morphogenesis	Biological process	-
ADAM17	6868	ADAM metallopeptidase domain 17	PDZ domain binding	Molecular function	12207026
MADCAM1	8174	mucosal vascular addressin cell adhesion molecule 1	extracellular matrix organization	Biological process	-
DZANK1	55184	double zinc ribbon and ankyrin repeat domains 1	zinc ion binding	Molecular function	-
PRKD1	5587	protein kinase D1	cytosol	Cellular component	-
POU2F3	25833	POU class 2 homeobox 3	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	12624109
TH	7054	tyrosine hydroxylase	cellular response to drug	Biological process	-
LOC440786	440786	uncharacterized LOC440786	immune response	Biological process	4596149
SIPA1	6494	signal-induced proliferation-associated 1	Golgi apparatus	Cellular component	-
AGTR2	186	angiotensin II receptor, type 2	cerebellar cortex development	Biological process	-
VRK2	7444	vaccinia related kinase 2	regulation of cell shape	Biological process	-
MAP2K2	5605	mitogen-activated protein kinase kinase 2	extracellular region	Cellular component	8388392
CHST3	9469	carbohydrate (chondroitin 6) sulfotransferase 3	chondroitin sulfate biosynthetic process	Biological process	-
OR2B2	81697	olfactory receptor, family 2, subfamily B, member 2	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
CADPS	8618	Ca++-dependent secretion activator	protein binding	Molecular function	17984325
RPS17	6218	ribosomal protein S17	ribosomal small subunit assembly	Biological process	-
KIF14	9928	kinesin family member 14	cell proliferation in forebrain	Biological process	-
COQ6	51004	coenzyme Q6 monooxygenase	small molecule metabolic process	Biological process	-
NRG1	3084	neuregulin 1	transcription cofactor activity	Molecular function	15073182
OR10A3	26496	olfactory receptor, family 10, subfamily A, member 3	sensory perception of smell	Biological process	1370859
ALS2	57679	amyotrophic lateral sclerosis 2 (juvenile)	protein localization	Biological process	-
SRC	6714	SRC proto-oncogene, non-receptor tyrosine kinase	bone resorption	Biological process	-
SUN5	140732	Sad1 and UNC84 domain containing 5	molecular_function	Molecular function	-
SOD1	6647	superoxide dismutase 1, soluble	cell aging	Biological process	12871978
DRGX	644168	dorsal root ganglia homeobox	dorsal spinal cord development	Biological process	-
FGL1	2267	fibrinogen-like 1	adipose tissue development	Biological process	-
RAB29	8934	RAB29, member RAS oncogene family	positive regulation of intracellular protein transport	Biological process	24788816
RAB38	23682	RAB38, member RAS oncogene family	endoplasmic reticulum	Cellular component	-
ERBB2	2064	erb-b2 receptor tyrosine kinase 2	protein C-terminus binding	Molecular function	15520177
UBB	7314	ubiquitin B	negative regulation of canonical Wnt signaling pathway	Biological process	-
GSK3B	2932	glycogen synthase kinase 3 beta	NF-kappaB binding	Molecular function	15465828
ATP6V0D1	9114	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1	transmembrane transport	Biological process	-
MANF	7873	mesencephalic astrocyte-derived neurotrophic factor	vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure	Biological process	-
CGA	1081	glycoprotein hormones, alpha polypeptide	positive regulation of cell migration	Biological process	20613903
RGCC	28984	regulator of cell cycle	protein binding	Molecular function	19162005
MESP1	55897	mesoderm posterior basic helix-loop-helix transcription factor 1	cardiac ventricle formation	Biological process	18297060
ST6GAL2	84620	ST6 beta-galactosamide alpha-2,6-sialyltranferase 2	growth	Biological process	12235148
TGFBI	7045	transforming growth factor, beta-induced, 68kDa	negative regulation of cell adhesion	Biological process	8024701
OR51E2	81285	olfactory receptor, family 51, subfamily E, member 2	steroid hormone receptor activity	Molecular function	19389702
TIMP1	7076	TIMP metallopeptidase inhibitor 1	metalloendopeptidase inhibitor activity	Molecular function	12714508
LSM3	27258	LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)	gene expression	Biological process	-
BMP8A	353500	bone morphogenetic protein 8a	regulation of energy homeostasis	Biological process	22579288
METTL10	399818	methyltransferase like 10	cytoplasm	Cellular component	-
AFF1	4299	AF4/FMR2 family, member 1	transcription elongation factor complex	Cellular component	22195968
NKD2	85409	naked cuticle homolog 2 (Drosophila)	negative regulation of canonical Wnt signaling pathway	Biological process	15687260
SARNP	84324	SAP domain containing ribonucleoprotein	poly(A) RNA binding	Molecular function	22658674
XXYLT1	152002	xyloside xylosyltransferase 1	transferase activity, transferring pentosyl groups	Molecular function	-
IL23R	149233	interleukin 23 receptor	inflammatory response	Biological process	-
BMPR1B	658	bone morphogenetic protein receptor, type IB	dorsal/ventral pattern formation	Biological process	-
SLC24A1	9187	solute carrier family 24 (sodium/potassium/calcium exchanger), member 1	response to light intensity	Biological process	9856482
MMP20	9313	matrix metallopeptidase 20	collagen catabolic process	Biological process	-
RIPK2	8767	receptor-interacting serine-threonine kinase 2	toll-like receptor 3 signaling pathway	Biological process	-
CA3	761	carbonic anhydrase III	cytosol	Cellular component	-
MAN1A1	4121	mannosidase, alpha, class 1A, member 1	integral component of membrane	Cellular component	-
KLC1	3831	kinesin light chain 1	microtubule-based movement	Biological process	-
STARD8	9754	StAR-related lipid transfer (START) domain containing 8	lipid binding	Molecular function	-
UBA52	7311	ubiquitin A-52 residue ribosomal protein fusion product 1	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	Biological process	-
PTK2	5747	protein tyrosine kinase 2	cytosol	Cellular component	-
BRCA1	672	breast cancer 1, early onset	regulation of cell proliferation	Biological process	10918303
HIST1H4D	8360	histone cluster 1, H4d	DNA methylation on cytosine	Biological process	-
ERVK-16	100616411	endogenous retrovirus group K, member 16	mRNA transport	Biological process	-
PLAT	5327	plasminogen activator, tissue	cellular protein modification process	Biological process	3087818
NR2C1	7181	nuclear receptor subfamily 2, group C, member 1	steroid hormone mediated signaling pathway	Biological process	-
HOXA1	3198	homeobox A1	facial nucleus development	Biological process	-
P2RX7	5027	purinergic receptor P2X, ligand gated ion channel, 7	positive regulation of mitochondrial depolarization	Biological process	-
CDH1	999	cadherin 1, type 1, E-cadherin (epithelial)	lateral plasma membrane	Cellular component	16338932
ZKSCAN8	7745	zinc finger with KRAB and SCAN domains 8	regulation of transcription, DNA-templated	Biological process	-
SRSF3	6428	serine/arginine-rich splicing factor 3	gene expression	Biological process	-
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	embryonic hindlimb morphogenesis	Biological process	-
BOC	91653	BOC cell adhesion associated, oncogene regulated	integral component of membrane	Cellular component	-
ATRN	8455	attractin	inflammatory response	Biological process	-
B4GALT4	8702	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4	small molecule metabolic process	Biological process	-
ZDHHC20	253832	zinc finger, DHHC-type containing 20	membrane	Cellular component	19946888
PPL	5493	periplakin	mitochondrion	Cellular component	-
AR	367	androgen receptor	nucleoplasm	Cellular component	-
ACVR1B	91	activin A receptor, type IB	positive regulation of pathway-restricted SMAD protein phosphorylation	Biological process	-
CLEC5A	23601	C-type lectin domain family 5, member A	innate immune response	Biological process	-
CYLD	1540	cylindromatosis (turban tumor syndrome)	cytosol	Cellular component	-
NPAP1	23742	nuclear pore associated protein 1	nuclear inner membrane	Cellular component	-
PPP1R12A	4659	protein phosphatase 1, regulatory subunit 12A	protein kinase binding	Molecular function	18477460
ZNF324	25799	zinc finger protein 324	metal ion binding	Molecular function	-
CAMKK2	10645	calcium/calmodulin-dependent protein kinase kinase 2, beta	protein phosphorylation	Biological process	11395482
NKX2-2	4821	NK2 homeobox 2	sequence-specific DNA binding transcription factor activity	Molecular function	-
ANKRD1	27063	ankyrin repeat domain 1 (cardiac muscle)	response to muscle stretch	Biological process	19608030
PSMD2	5708	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	antigen processing and presentation of peptide antigen via MHC class I	Biological process	-
ERAP1	51752	endoplasmic reticulum aminopeptidase 1	extracellular exosome	Cellular component	19199708
UCN	7349	urocortin	positive regulation of cAMP biosynthetic process	Biological process	-
SLC35F2	54733	solute carrier family 35, member F2	integral component of membrane	Cellular component	-
NME7	29922	NME/NM23 family member 7	determination of left/right symmetry	Biological process	-
ARL6IP5	10550	ADP-ribosylation factor-like 6 interacting protein 5	positive regulation of apoptotic process	Biological process	18387645
TMEM201	199953	transmembrane protein 201	actin filament binding	Molecular function	-
KIDINS220	57498	kinase D-interacting substrate, 220kDa	regulation of protein kinase activity	Biological process	-
LY6D	8581	lymphocyte antigen 6 complex, locus D	membrane	Cellular component	7790363
TDRD1	56165	tudor domain containing 1	multicellular organismal development	Biological process	-
PTPN5	84867	protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)	phosphotyrosine binding	Molecular function	16441242
PTPRM	5797	protein tyrosine phosphatase, receptor type, M	positive regulation of vasodilation	Biological process	-
CACNA1C	775	calcium channel, voltage-dependent, L type, alpha 1C subunit	voltage-gated calcium channel complex	Cellular component	12130699
PVRL2	5819	poliovirus receptor-related 2 (herpesvirus entry mediator B)	establishment of mitochondrion localization	Biological process	-
LAMP5	24141	lysosomal-associated membrane protein family, member 5	growth cone membrane	Cellular component	-
GRIN2A	2903	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	zinc ion binding	Molecular function	-
KCNIP3	30818	Kv channel interacting protein 3, calsenilin	protein binding	Molecular function	16189514
ULK2	9706	unc-51 like autophagy activating kinase 2	protein autophosphorylation	Biological process	18936157
SNX1	6642	sorting nexin 1	transferrin receptor binding	Molecular function	9819414
NR2E3	10002	nuclear receptor subfamily 2, group E, member 3	steroid hormone mediated signaling pathway	Biological process	-
IGHG4	3503	immunoglobulin heavy constant gamma 4 (G4m marker)	extracellular region	Cellular component	-
KDM1A	23028	lysine (K)-specific demethylase 1A	histone demethylase activity (H3-K4 specific)	Molecular function	15620353
VNN1	8876	vanin 1	acute inflammatory response	Biological process	14966568
BAZ1B	9031	bromodomain adjacent to zinc finger domain, 1B	ATP binding	Molecular function	-
SNTA1	6640	syntrophin, alpha 1	neuromuscular junction	Cellular component	-
CYP2A6	1548	cytochrome P450, family 2, subfamily A, polypeptide 6	xenobiotic metabolic process	Biological process	-
DMD	1756	dystrophin	regulation of heart rate	Biological process	19027585
TUBG2	27175	tubulin, gamma 2	microtubule cytoskeleton	Cellular component	10903841
OR8I2	120586	olfactory receptor, family 8, subfamily I, member 2	olfactory receptor activity	Molecular function	-
PCYT1A	5130	phosphate cytidylyltransferase 1, choline, alpha	choline-phosphate cytidylyltransferase activity	Molecular function	-
MID1IP1	58526	MID1 interacting protein 1	positive regulation of fatty acid biosynthetic process	Biological process	-
HIP1	3092	huntingtin interacting protein 1	activation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	11788820
PAPPA-AS1	493913	PAPPA antisense RNA 1	endoplasmic reticulum membrane	Cellular component	-
CHMP4C	92421	charged multivesicular body protein 4C	nucleus organization	Biological process	20616062
PIN4	5303	peptidylprolyl cis/trans isomerase, NIMA-interacting 4	rRNA processing	Biological process	19369196
TMSB15B	286527	thymosin beta 15B	cytoplasm	Cellular component	-
HBA2	3040	hemoglobin, alpha 2	peroxidase activity	Molecular function	19740759
NLGN3	54413	neuroligin 3	visual learning	Biological process	-
KMT2A	4297	lysine (K)-specific methyltransferase 2A	chromatin organization	Biological process	-
HMGA2	8091	high mobility group AT-hook 2	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	14627817
POLDIP3	84271	polymerase (DNA-directed), delta interacting protein 3	nucleotide binding	Molecular function	-
TCEAL2	140597	transcription elongation factor A (SII)-like 2	regulation of transcription, DNA-templated	Biological process	-
ZRANB3	84083	zinc finger, RAN-binding domain containing 3	nuclear replication fork	Cellular component	22704558
CHD5	26038	chromodomain helicase DNA binding protein 5	NuRD complex	Cellular component	-
FAF2	23197	Fas associated factor family member 2	ubiquitin binding	Molecular function	18775313
PARVG	64098	parvin, gamma	cytoplasm	Cellular component	-
WRN	7486	Werner syndrome, RecQ helicase-like	DNA metabolic process	Biological process	16622405
ZNF728	388523	zinc finger protein 728	intracellular	Cellular component	-
OGT	8473	O-linked N-acetylglucosamine (GlcNAc) transferase	nucleus	Cellular component	21285374
F2RL1	2150	coagulation factor II (thrombin) receptor-like 1	positive regulation of cytokine secretion involved in immune response	Biological process	11441110
GAK	2580	cyclin G associated kinase	clathrin-mediated endocytosis	Biological process	-
ZNF812	729648	zinc finger protein 812	transcription, DNA-templated	Biological process	-
P2RX7	5027	purinergic receptor P2X, ligand gated ion channel, 7	positive regulation of interleukin-1 alpha secretion	Biological process	-
GFPT1	2673	glutamine--fructose-6-phosphate transaminase 1	post-translational protein modification	Biological process	-
CENPL	91687	centromere protein L	CENP-A containing nucleosome assembly	Biological process	-
JARID2	3720	jumonji, AT rich interactive domain 2	liver development	Biological process	-
GTF2H2	2966	general transcription factor IIH, polypeptide 2, 44kDa	DNA repair	Biological process	-
FGF19	9965	fibroblast growth factor 19	neural crest cell migration	Biological process	-
KLK3	354	kallikrein-related peptidase 3	protein binding	Molecular function	1725227
RBM15B	29890	RNA binding motif protein 15B	viral process	Biological process	-
PHF13	148479	PHD finger protein 13	nucleus	Cellular component	19638409
PTTG1IP	754	pituitary tumor-transforming 1 interacting protein	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator	Biological process	24506068
HSD17B4	3295	hydroxysteroid (17-beta) dehydrogenase 4	membrane	Cellular component	16210410
FABP3	2170	fatty acid binding protein 3, muscle and heart	response to insulin	Biological process	-
KIF3C	3797	kinesin family member 3C	cytosol	Cellular component	-
BCL2L1	598	BCL2-like 1	negative regulation of anoikis	Biological process	15006356
DDX58	23586	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	cytoplasm	Cellular component	-
APBB1	322	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	transcription factor binding	Molecular function	-
UCP3	7352	uncoupling protein 3 (mitochondrial, proton carrier)	lipid metabolic process	Biological process	10935638
AKT1	207	v-akt murine thymoma viral oncogene homolog 1	intrinsic apoptotic signaling pathway	Biological process	-
AP3D1	8943	adaptor-related protein complex 3, delta 1 subunit	anterograde synaptic vesicle transport	Biological process	-
ING4	51147	inhibitor of growth family, member 4	protein acetylation	Biological process	12750254
ST6GALNAC2	10610	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2	sialyltransferase activity	Molecular function	-
PIN4	5303	peptidylprolyl cis/trans isomerase, NIMA-interacting 4	protein peptidyl-prolyl isomerization	Biological process	-
PDLIM2	64236	PDZ and LIM domain 2 (mystique)	muscle alpha-actinin binding	Molecular function	-
ATP9B	374868	ATPase, class II, type 9B	magnesium ion binding	Molecular function	-
TH	7054	tyrosine hydroxylase	catecholamine biosynthetic process	Biological process	-
UBE2B	7320	ubiquitin-conjugating enzyme E2B	protein stabilization	Biological process	18339854
RDM1	201299	RAD52 motif containing 1	Cajal body	Cellular component	-
USP19	10869	ubiquitin specific peptidase 19	positive regulation of cell cycle process	Biological process	-
OR9A2	135924	olfactory receptor, family 9, subfamily A, member 2	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
PIK3C3	5289	phosphatidylinositol 3-kinase, catalytic subunit type 3	protein kinase activity	Molecular function	-
CD86	942	CD86 molecule	response to drug	Biological process	-
CRHBP	1393	corticotropin releasing hormone binding protein	protein binding	Molecular function	18234674
TIPIN	54962	TIMELESS interacting protein	nucleoplasm	Cellular component	-
IFIH1	64135	interferon induced with helicase C domain 1	protein binding	Molecular function	16127453
TRAF5	7188	TNF receptor-associated factor 5	apoptotic process	Biological process	-
FBLN2	2199	fibulin 2	proteinaceous extracellular matrix	Cellular component	-
SLN	6588	sarcolipin	negative regulation of catalytic activity	Biological process	12032137
TPD52L1	7164	tumor protein D52-like 1	regulation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	14761963
HYAL2	8692	hyaluronoglucosaminidase 2	Golgi membrane	Cellular component	21740893
PIK3CD	5293	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	adaptive immune response	Biological process	17290298
FAU	2197	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed	cellular_component	Cellular component	-
CLCN3	1182	chloride channel, voltage-sensitive 3	early endosome membrane	Cellular component	-
RASGRP3	25780	RAS guanyl releasing protein 3 (calcium and DAG-regulated)	MAPK cascade	Biological process	10934204
EMX1	2016	empty spiracles homeobox 1	brain morphogenesis	Biological process	-
IGSF3	3321	immunoglobulin superfamily, member 3	cell surface	Cellular component	19581412
NDNF	79625	neuron-derived neurotrophic factor	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan	Biological process	-
PAPSS1	9061	3'-phosphoadenosine 5'-phosphosulfate synthase 1	sulfate adenylyltransferase (ATP) activity	Molecular function	-
SURF2	6835	surfeit 2	biological_process	Biological process	-
RNASEL	6041	ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)	negative regulation of viral genome replication	Biological process	19923450
CTDSP1	58190	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1	negative regulation of G1/S transition of mitotic cell cycle	Biological process	-
NHP2L1	4809	NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)	protein binding	Molecular function	17412961
PLK1	5347	polo-like kinase 1	mitotic cell cycle	Biological process	-
CFP	5199	complement factor properdin	extracellular matrix	Cellular component	20551380
RPS28	6234	ribosomal protein S28	viral transcription	Biological process	-
PLCB2	5330	phospholipase C, beta 2	lipid catabolic process	Biological process	-
GSX1	219409	GS homeobox 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	11731616
CDK12	51755	cyclin-dependent kinase 12	RNA splicing	Biological process	-
OR1L8	138881	olfactory receptor, family 1, subfamily L, member 8	G-protein coupled receptor signaling pathway	Biological process	-
TDG	6996	thymine-DNA glycosylase	damaged DNA binding	Molecular function	9489705
BIN1	274	bridging integrator 1	protein heterodimerization activity	Molecular function	-
RYR2	6262	ryanodine receptor 2 (cardiac)	calcium-release channel activity	Molecular function	17921453
CRY2	1408	cryptochrome circadian clock 2	protein import into nucleus	Biological process	-
PCF11	51585	PCF11 cleavage and polyadenylation factor subunit	nucleoplasm	Cellular component	-
CARD18	59082	caspase recruitment domain family, member 18	regulation of apoptotic process	Biological process	-
TBL3	10607	transducin (beta)-like 3	nucleus	Cellular component	-
ZBED9	114821	zinc finger, BED-type containing 9	sequence-specific DNA binding transcription factor activity	Molecular function	-
IL1RN	3557	interleukin 1 receptor antagonist	female pregnancy	Biological process	-
PRPF4	9128	pre-mRNA processing factor 4	U4/U6 x U5 tri-snRNP complex	Cellular component	-
WDTC1	23038	WD and tetratricopeptide repeats 1	multicellular organism growth	Biological process	-
USP30	84749	ubiquitin specific peptidase 30	regulation of proteasomal protein catabolic process	Biological process	-
FGFR3	2261	fibroblast growth factor receptor 3	protein autophosphorylation	Biological process	11294897
ZSCAN25	221785	zinc finger and SCAN domain containing 25	metal ion binding	Molecular function	-
MST1R	4486	macrophage stimulating 1 receptor	macrophage colony-stimulating factor receptor activity	Molecular function	9045873
ATP6V1B2	526	ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2	cellular iron ion homeostasis	Biological process	-
CTSH	1512	cathepsin H	kininogen binding	Molecular function	-
IGLC6	3542	immunoglobulin lambda constant 6 (Kern+Oz- marker, gene/pseudogene)	complement activation	Biological process	-
DDO	8528	D-aspartate oxidase	receptor binding	Molecular function	20178365
C14orf2	9556	chromosome 14 open reading frame 2	cellular_component	Cellular component	-
PTEN	5728	phosphatase and tensin homolog	cell projection	Cellular component	10760291
PTPN11	5781	protein tyrosine phosphatase, non-receptor type 11	ERBB signaling pathway	Biological process	15133037
MAGED1	9500	melanoma antigen family D1	regulation of apoptotic process	Biological process	15930293
STAT3	6774	signal transducer and activator of transcription 3 (acute-phase response factor)	growth hormone receptor signaling pathway	Biological process	10925297
MAB21L1	4081	mab-21-like 1 (C. elegans)	nucleus	Cellular component	-
TBP	6908	TATA box binding protein	sequence-specific DNA binding transcription factor activity	Molecular function	-
TXNL1	9352	thioredoxin-like 1	cell redox homeostasis	Biological process	-
TCEA2	6919	transcription elongation factor A (SII), 2	zinc ion binding	Molecular function	-
TGIF1	7050	TGFB-induced factor homeobox 1	chromatin binding	Molecular function	-
C9orf135	138255	chromosome 9 open reading frame 135	integral component of membrane	Cellular component	-
SYT10	341359	synaptotagmin X	protein heterodimerization activity	Molecular function	-
SDHC	6391	succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa	mitochondrial electron transport, succinate to ubiquinone	Biological process	-
TESC	54997	tescalcin	calcium ion binding	Molecular function	11696366
SCAMP2	10066	secretory carrier membrane protein 2	protein transport	Biological process	15840657
AKAP13	11214	A kinase (PRKA) anchor protein 13	neurotrophin TRK receptor signaling pathway	Biological process	-
HEXA	3073	hexosaminidase A (alpha polypeptide)	glycosphingolipid metabolic process	Biological process	-
PCDHB4	56131	protocadherin beta 4	intermediate filament cytoskeleton	Cellular component	-
PPM1K	152926	protein phosphatase, Mg2+/Mn2+ dependent, 1K	metal ion binding	Molecular function	-
ADAM8	101	ADAM metallopeptidase domain 8	integral component of plasma membrane	Cellular component	18397961
TRIM58	25893	tripartite motif containing 58	intracellular	Cellular component	-
ACAT1	38	acetyl-CoA acetyltransferase 1	response to hormone	Biological process	-
SUZ12	23512	SUZ12 polycomb repressive complex 2 subunit	sequence-specific DNA binding	Molecular function	-
NPY5R	4889	neuropeptide Y receptor Y5	G-protein coupled receptor signaling pathway	Biological process	8824284
POR	5447	P450 (cytochrome) oxidoreductase	electron carrier activity	Molecular function	-
PRTFDC1	56952	phosphoribosyl transferase domain containing 1	hypoxanthine phosphoribosyltransferase activity	Molecular function	21054786
PAPOLA	10914	poly(A) polymerase alpha	nucleoplasm	Cellular component	-
PARN	5073	poly(A)-specific ribonuclease	RNA modification	Biological process	9736620
FMO2	2327	flavin containing monooxygenase 2 (non-functional)	flavin adenine dinucleotide binding	Molecular function	-
RCOR3	55758	REST corepressor 3	regulation of transcription, DNA-templated	Biological process	-
FGFR1	2260	fibroblast growth factor receptor 1	middle ear morphogenesis	Biological process	-
HDX	139324	highly divergent homeobox	DNA binding	Molecular function	-
NR4A2	4929	nuclear receptor subfamily 4, group A, member 2	response to inorganic substance	Biological process	-
NOX5	79400	NADPH oxidase, EF-hand calcium binding domain 5	calcium ion binding	Molecular function	-
OSGEP	55644	O-sialoglycoprotein endopeptidase	EKC/KEOPS complex	Cellular component	-
AGO4	192670	argonaute RISC catalytic component 4	pre-miRNA processing	Biological process	19966796
DHCR24	1718	24-dehydrocholesterol reductase	cytosol	Cellular component	-
DAB2IP	153090	DAB2 interacting protein	vascular endothelial growth factor receptor 2 binding	Molecular function	19033661
CDKN1C	1028	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	protein binding	Molecular function	16289477
HLTF	6596	helicase-like transcription factor	protein polyubiquitination	Biological process	-
CD300LB	124599	CD300 molecule-like family member b	integral component of membrane	Cellular component	-
PDIA6	10130	protein disulfide isomerase family A, member 6	cell redox homeostasis	Biological process	-
NCOA2	10499	nuclear receptor coactivator 2	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
NAT8B	51471	N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene)	integral component of membrane	Cellular component	11397015
SCLY	51540	selenocysteine lyase	pyridoxal phosphate binding	Molecular function	-
AQP1	358	aquaporin 1 (Colton blood group)	secretory granule organization	Biological process	-
CADPS2	93664	Ca++-dependent secretion activator 2	presynaptic membrane	Cellular component	-
SRGAP2C	653464	SLIT-ROBO Rho GTPase activating protein 2C	negative regulation of filopodium assembly	Biological process	22559944
MGLL	11343	monoglyceride lipase	regulation of axon extension	Biological process	-
DRD4	1815	dopamine receptor D4	cell cortex	Cellular component	-
EZR	7430	ezrin	astrocyte projection	Cellular component	-
ANKRD46	157567	ankyrin repeat domain 46	integral component of membrane	Cellular component	-
NCBP2	22916	nuclear cap binding protein subunit 2, 20kDa	termination of RNA polymerase II transcription	Biological process	-
MSX1	4487	msh homeobox 1	epithelial to mesenchymal transition involved in endocardial cushion formation	Biological process	-
IGBP1	3476	immunoglobulin (CD79A) binding protein 1	positive regulation of dephosphorylation	Biological process	-
ZIK1	284307	zinc finger protein interacting with K protein 1	transcription, DNA-templated	Biological process	-
ACSM1	116285	acyl-CoA synthetase medium-chain family member 1	energy derivation by oxidation of organic compounds	Biological process	11470804
HOMER1	9456	homer scaffolding protein 1	behavioral response to cocaine	Biological process	-
VPS4B	9525	vacuolar protein sorting 4 homolog B (S. cerevisiae)	cell separation after cytokinesis	Biological process	20616062
SOS1	6654	son of sevenless homolog 1 (Drosophila)	plasma membrane	Cellular component	-
FRMPD3	84443	FERM and PDZ domain containing 3	cytoskeleton	Cellular component	-
CHMP4B	128866	charged multivesicular body protein 4B	extracellular exosome	Cellular component	19056867
ABCG2	9429	ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)	nucleoplasm	Cellular component	-
PDCD6IP	10015	programmed cell death 6 interacting protein	focal adhesion	Cellular component	21423176
NLRC4	58484	NLR family, CARD domain containing 4	activation of innate immune response	Biological process	-
TMEM132A	54972	transmembrane protein 132A	extracellular exosome	Cellular component	23533145
RNF126	55658	ring finger protein 126	protein monoubiquitination	Biological process	23277564
OVCH1	341350	ovochymase 1	extracellular region	Cellular component	-
THEM4	117145	thioesterase superfamily member 4	neurotrophin TRK receptor signaling pathway	Biological process	-
NOC2L	26155	nucleolar complex associated 2 homolog (S. cerevisiae)	transcription, DNA-templated	Biological process	-
AIF1	199	allograft inflammatory factor 1	Rac protein signal transduction	Biological process	-
GRK5	2869	G protein-coupled receptor kinase 5	termination of G-protein coupled receptor signaling pathway	Biological process	-
SMAD3	4088	SMAD family member 3	evasion or tolerance of host defenses by virus	Biological process	15334054
BCL2	596	B-cell CLL/lymphoma 2	positive regulation of cell growth	Biological process	8022822
INSL6	11172	insulin-like 6	extracellular region	Cellular component	-
NANS	54187	N-acetylneuraminic acid synthase	post-translational protein modification	Biological process	-
B4GAT1	11041	beta-1,4-glucuronyltransferase 1	extracellular exosome	Cellular component	23376485
MYOD1	4654	myogenic differentiation 1	myotube differentiation involved in skeletal muscle regeneration	Biological process	-
CD86	942	CD86 molecule	intracellular membrane-bounded organelle	Cellular component	-
RGS14	10636	regulator of G-protein signaling 14	regulation of DNA-templated transcription in response to stress	Biological process	-
USP1	7398	ubiquitin specific peptidase 1	protein binding	Molecular function	18082604
C19orf70	125988	chromosome 19 open reading frame 70	mitochondrion	Cellular component	-
NCOA6	23054	nuclear receptor coactivator 6	DNA replication	Biological process	11443112
KRT20	54474	keratin 20, type I	intermediate filament	Cellular component	8359595
STAT1	6772	signal transducer and activator of transcription 1, 91kDa	response to hydrogen peroxide	Biological process	-
GABRA5	2558	gamma-aminobutyric acid (GABA) A receptor, alpha 5	signal transduction	Biological process	1321750
PROKR1	10887	prokineticin receptor 1	neuropeptide Y receptor activity	Molecular function	-
TUBA4A	7277	tubulin, alpha 4a	GTPase activity	Molecular function	-
FOXJ1	2302	forkhead box J1	glomerular parietal epithelial cell development	Biological process	9530170
LAMA1	284217	laminin, alpha 1	cell adhesion	Biological process	-
NODAL	4838	nodal growth differentiation factor	negative regulation of androgen receptor signaling pathway	Biological process	21656830
NFKB1	4790	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	cellular response to interleukin-6	Biological process	22357537
ZNF501	115560	zinc finger protein 501	transcription, DNA-templated	Biological process	-
SF1	7536	splicing factor 1	spliceosomal complex assembly	Biological process	8752089
RPL37A	6168	ribosomal protein L37a	extracellular exosome	Cellular component	20458337
GAS2L3	283431	growth arrest-specific 2 like 3	cytoplasm	Cellular component	-
ST3GAL2	6483	ST3 beta-galactoside alpha-2,3-sialyltransferase 2	protein N-linked glycosylation via asparagine	Biological process	-
OR4A5	81318	olfactory receptor, family 4, subfamily A, member 5	olfactory receptor activity	Molecular function	-
MT1X	4501	metallothionein 1X	cytoplasm	Cellular component	8619255
ZC3HAV1	56829	zinc finger CCCH-type, antiviral 1	positive regulation of interferon-beta production	Biological process	21102435
IL6	3569	interleukin 6	positive regulation of immunoglobulin secretion	Biological process	3491322
PABPC1	26986	poly(A) binding protein, cytoplasmic 1	mRNA stabilization	Biological process	11997512
SLC6A11	6538	solute carrier family 6 (neurotransmitter transporter), member 11	gamma-aminobutyric acid:sodium symporter activity	Molecular function	-
ACOX2	8309	acyl-CoA oxidase 2, branched chain	peroxisome	Cellular component	2079609
CYSLTR1	10800	cysteinyl leukotriene receptor 1	defense response	Biological process	10391245
FOXM1	2305	forkhead box M1	nucleus	Cellular component	-
SOX5	6660	SRY (sex determining region Y)-box 5	cell fate commitment	Biological process	-
FGF8	2253	fibroblast growth factor 8 (androgen-induced)	odontogenesis	Biological process	17394220
ASUN	55726	asunder spermatogenesis regulator	mitotic spindle organization	Biological process	23097494
JARID2	3720	jumonji, AT rich interactive domain 2	stem cell differentiation	Biological process	-
RIPK2	8767	receptor-interacting serine-threonine kinase 2	toll-like receptor 4 signaling pathway	Biological process	-
FPGS	2356	folylpolyglutamate synthase	mitochondrial inner membrane	Cellular component	-
FOXP3	50943	forkhead box P3	positive regulation of transcription from RNA polymerase II promoter	Biological process	19276356
EIF2B4	8890	eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa	oligodendrocyte development	Biological process	15217090
SCNN1G	6340	sodium channel, non voltage gated 1 gamma subunit	response to stimulus	Biological process	-
ITGB1	3688	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	recycling endosome	Cellular component	-
KCNK10	54207	potassium channel, two pore domain subfamily K, member 10	potassium ion transmembrane transport	Biological process	-
KLHL12	59349	kelch-like family member 12	protein binding	Molecular function	16189514
NFE2L1	4779	nuclear factor, erythroid 2-like 1	RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
PLCB4	5332	phospholipase C, beta 4	cytosol	Cellular component	-
PRDX3	10935	peroxiredoxin 3	peptidyl-cysteine oxidation	Biological process	21850687
DDX23	9416	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23	RNA splicing, via transesterification reactions	Biological process	9409622
EPHA6	285220	EPH receptor A6	cellular_component	Cellular component	-
B4GALT2	8704	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2	small molecule metabolic process	Biological process	-
MAPRE1	22919	microtubule-associated protein, RP/EB family, member 1	protein C-terminus binding	Molecular function	7606712
ABCD4	5826	ATP-binding cassette, sub-family D (ALD), member 4	ATPase activity, coupled to transmembrane movement of substances	Molecular function	9266848
SUPT5H	6829	suppressor of Ty 5 homolog (S. cerevisiae)	negative regulation of transcription from RNA polymerase II promoter	Biological process	10075709
ALG2	85365	ALG2, alpha-1,3/1,6-mannosyltransferase	glycolipid 6-alpha-mannosyltransferase activity	Molecular function	-
NRAS	4893	neuroblastoma RAS viral (v-ras) oncogene homolog	extracellular exosome	Cellular component	20458337
DNMT3L	29947	DNA (cytosine-5-)-methyltransferase 3-like	gene expression	Biological process	-
MGA	23269	MGA, MAX dimerization protein	transcription factor complex	Cellular component	-
CD86	942	CD86 molecule	innate immune response	Biological process	-
TLN2	83660	talin 2	plasma membrane	Cellular component	-
AKT1	207	v-akt murine thymoma viral oncogene homolog 1	phosphorylation	Biological process	20333297
PEX1	5189	peroxisomal biogenesis factor 1	ATP binding	Molecular function	16854980
PDIA3	2923	protein disulfide isomerase family A, member 3	oxidation-reduction process	Biological process	22013210
NKIRAS1	28512	NFKB inhibitor interacting Ras-like 1	I-kappaB kinase/NF-kappaB signaling	Biological process	10657303
EPHA3	2042	EPH receptor A3	fasciculation of sensory neuron axon	Biological process	-
TIMM9	26520	translocase of inner mitochondrial membrane 9 homolog (yeast)	protein import into mitochondrial inner membrane	Biological process	14726512
UBE2S	27338	ubiquitin-conjugating enzyme E2S	ubiquitin conjugating enzyme activity	Molecular function	21376237
NDUFS3	4722	NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)	mitochondrial respiratory chain complex I	Cellular component	9878551
PDILT	204474	protein disulfide isomerase-like, testis expressed	spermatid development	Biological process	-
MRPL13	28998	mitochondrial ribosomal protein L13	mitochondrial large ribosomal subunit	Cellular component	11279069
CLIP1	6249	CAP-GLY domain containing linker protein 1	cytoplasmic microtubule	Cellular component	-
HES2	54626	hes family bHLH transcription factor 2	nucleus	Cellular component	-
CLCN4	1183	chloride channel, voltage-sensitive 4	early endosome membrane	Cellular component	-
TBR1	10716	T-box, brain, 1	commitment of neuronal cell to specific neuron type in forebrain	Biological process	-
VPS33A	65082	vacuolar protein sorting 33 homolog A (S. cerevisiae)	lysosome localization	Biological process	15790593
GPR139	124274	G protein-coupled receptor 139	integral component of membrane	Cellular component	-
CAPN3	825	calpain 3, (p94)	nucleus	Cellular component	19386580
CCDC151	115948	coiled-coil domain containing 151	centriole	Cellular component	-
MOV10	4343	Mov10 RISC complex RNA helicase	cytoplasmic mRNA processing body	Cellular component	16289642
CTBS	1486	chitobiase, di-N-acetyl-	lysosome	Cellular component	-
THAP11	57215	THAP domain containing 11	cytoplasm	Cellular component	-
APOA4	337	apolipoprotein A-IV	retinoid metabolic process	Biological process	-
CKAP5	9793	cytoskeleton associated protein 5	mitotic cell cycle	Biological process	-
EGFL6	25975	EGF-like-domain, multiple 6	basement membrane	Cellular component	-
HDAC3	8841	histone deacetylase 3	negative regulation of transcription, DNA-templated	Biological process	16924111
DSG2	1829	desmoglein 2	maternal process involved in female pregnancy	Biological process	-
PXDN	7837	peroxidasin	response to oxidative stress	Biological process	-
CATIP	375307	ciliogenesis associated TTC17 interacting protein	calmodulin binding	Molecular function	-
CCDC77	84318	coiled-coil domain containing 77	centrosome	Cellular component	21399614
BTN2A2	10385	butyrophilin, subfamily 2, member A2	extracellular exosome	Cellular component	23376485
IL10	3586	interleukin 10	cellular response to lipopolysaccharide	Biological process	14971032
TNFRSF10C	8794	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	signal transduction	Biological process	9314565
PSAT1	29968	phosphoserine aminotransferase 1	cellular amino acid biosynthetic process	Biological process	-
PEX14	5195	peroxisomal biogenesis factor 14	microtubule binding	Molecular function	21525035
PDCD6	10016	programmed cell death 6	endosome	Cellular component	-
CEBPB	1051	CCAAT/enhancer binding protein (C/EBP), beta	negative regulation of neuron apoptotic process	Biological process	-
STAT3	6774	signal transducer and activator of transcription 3 (acute-phase response factor)	positive regulation of Notch signaling pathway	Biological process	-
PAFAH2	5051	platelet-activating factor acetylhydrolase 2, 40kDa	lipid metabolic process	Biological process	8955149
CSF1	1435	colony stimulating factor 1 (macrophage)	positive regulation of microglial cell migration	Biological process	19100238
EPN2	22905	epsin 2	intracellular membrane-bounded organelle	Cellular component	-
CHCHD5	84269	coiled-coil-helix-coiled-coil-helix domain containing 5	aerobic respiration	Biological process	-
ARHGEF1	9138	Rho guanine nucleotide exchange factor (GEF) 1	GTPase activator activity	Molecular function	-
MSR1	4481	macrophage scavenger receptor 1	protein binding	Molecular function	17237231
ATOH1	474	atonal homolog 1 (Drosophila)	central nervous system development	Biological process	8872459
CDK15	65061	cyclin-dependent kinase 15	protein phosphorylation	Biological process	-
RAB24	53917	RAB24, member RAS oncogene family	intracellular protein transport	Biological process	-
PACSIN2	11252	protein kinase C and casein kinase substrate in neurons 2	membrane-bounded vesicle	Cellular component	-
ITGB2	3689	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	membrane	Cellular component	19946888
BDH2	56898	3-hydroxybutyrate dehydrogenase, type 2	mitochondrion	Cellular component	16380372
AMPD1	270	adenosine monophosphate deaminase 1	purine-containing compound salvage	Biological process	-
DMRTA2	63950	DMRT-like family A2	skeletal muscle cell differentiation	Biological process	-
WEE1	7465	WEE1 G2 checkpoint kinase	cell division	Biological process	-
CTH	1491	cystathionine gamma-lyase	calmodulin binding	Molecular function	-
PAX3	5077	paired box 3	muscle organ development	Biological process	-
KATNA1	11104	katanin p60 (ATPase containing) subunit A 1	cytoplasm	Cellular component	19261606
ATRN	8455	attractin	extracellular space	Cellular component	16502470
KRT9	3857	keratin 9, type I	intermediate filament	Cellular component	-
UBB	7314	ubiquitin B	TRIF-dependent toll-like receptor signaling pathway	Biological process	-
HDAC3	8841	histone deacetylase 3	negative regulation of apoptotic process	Biological process	10777477
CHRNA1	1134	cholinergic receptor, nicotinic, alpha 1 (muscle)	neuromuscular process	Biological process	9546329
MTDH	92140	metadherin	positive regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	16452207
EFNB1	1947	ephrin-B1	ephrin receptor binding	Molecular function	-
MRPL13	28998	mitochondrial ribosomal protein L13	mitochondrial translational termination	Biological process	-
PAFAH1B1	5048	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	microtubule binding	Molecular function	10729324
EXT1	2131	exostosin glycosyltransferase 1	endoderm development	Biological process	-
AGT	183	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	positive regulation of NAD(P)H oxidase activity	Biological process	17159080
STRAP	11171	serine/threonine kinase receptor associated protein	maintenance of gastrointestinal epithelium	Biological process	17929853
PIGU	128869	phosphatidylinositol glycan anchor biosynthesis, class U	post-translational protein modification	Biological process	-
LCE3A	353142	late cornified envelope 3A	keratinization	Biological process	-
INPP4A	3631	inositol polyphosphate-4-phosphatase, type I, 107kDa	phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity	Molecular function	-
PINK1	65018	PTEN induced putative kinase 1	nucleus	Cellular component	24798695
SSTR1	6751	somatostatin receptor 1	cell surface receptor signaling pathway	Biological process	1346068
RAMP1	10267	receptor (G protein-coupled) activity modifying protein 1	protein localization to plasma membrane	Biological process	10882736
GTF2F1	2962	general transcription factor IIF, polypeptide 1, 74kDa	nucleus	Cellular component	-
UQCRFS1	7386	ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1	hydrogen ion transmembrane transport	Biological process	-
KCNQ1	3784	potassium channel, voltage gated KQT-like subfamily Q, member 1	voltage-gated potassium channel activity	Molecular function	16002409
ZNF362	149076	zinc finger protein 362	transcription, DNA-templated	Biological process	-
WNT7B	7477	wingless-type MMTV integration site family, member 7B	mammary gland epithelium development	Biological process	8168088
RPL6	6128	ribosomal protein L6	viral process	Biological process	-
OLA1	29789	Obg-like ATPase 1	protein binding	Molecular function	22190034
PCBP1	5093	poly(rC) binding protein 1	membrane	Cellular component	19946888
PTPN14	5784	protein tyrosine phosphatase, non-receptor type 14	regulation of protein export from nucleus	Biological process	22948661
SLC52A3	113278	solute carrier family 52 (riboflavin transporter), member 3	apical plasma membrane	Cellular component	-
REPS1	85021	RALBP1 associated Eps domain containing 1	plasma membrane	Cellular component	20946875
ATP5B	506	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide	osteoblast differentiation	Biological process	16210410
CEP250	11190	centrosomal protein 250kDa	protein complex	Cellular component	10880350
OR4F4	26682	olfactory receptor, family 4, subfamily F, member 4	integral component of membrane	Cellular component	-
ATP1B1	481	ATPase, Na+/K+ transporting, beta 1 polypeptide	sodium:potassium-exchanging ATPase activity	Molecular function	10636900
MAPK9	5601	mitogen-activated protein kinase 9	protein targeting to mitochondrion	Biological process	-
SEC24C	9632	SEC24 family member C	cellular protein metabolic process	Biological process	-
ADGRF3	165082	adhesion G protein-coupled receptor F3	G-protein coupled receptor activity	Molecular function	-
ELK1	2002	ELK1, member of ETS oncogene family	neuronal cell body	Cellular component	-
GPR142	350383	G protein-coupled receptor 142	cytoplasm	Cellular component	-
HDAC9	9734	histone deacetylase 9	repressing transcription factor binding	Molecular function	-
WIPF1	7456	WAS/WASL interacting protein family, member 1	innate immune response	Biological process	-
PRDX3	10935	peroxiredoxin 3	maternal placenta development	Biological process	-
CASK	8573	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	nuclear matrix	Cellular component	18664494
OR4P4	81300	olfactory receptor, family 4, subfamily P, member 4	plasma membrane	Cellular component	-
PHOSPHO2	493911	phosphatase, orphan 2	phosphatase activity	Molecular function	-
PIK3CD	5293	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	protein phosphorylation	Biological process	9113989
KLF4	9314	Kruppel-like factor 4 (gut)	RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription	Molecular function	21539536
CDK11B	984	cyclin-dependent kinase 11B	regulation of mRNA processing	Biological process	12501247
SIRT2	22933	sirtuin 2	tubulin deacetylase activity	Molecular function	24177535
GPRASP1	9737	G protein-coupled receptor associated sorting protein 1	protein binding	Molecular function	15086532
KIF1C	10749	kinesin family member 1C	endoplasmic reticulum	Cellular component	9685376
POLR2D	5433	polymerase (RNA) II (DNA directed) polypeptide D	cytoplasmic mRNA processing body	Cellular component	-
C1orf210	149466	chromosome 1 open reading frame 210	integral component of membrane	Cellular component	-
COL9A3	1299	collagen, type IX, alpha 3	extracellular matrix structural constituent conferring tensile strength	Molecular function	8660302
EXPH5	23086	exophilin 5	multivesicular body sorting pathway	Biological process	19966785
RND3	390	Rho family GTPase 3	cell adhesion	Biological process	9531558
BCAT1	586	branched chain amino-acid transaminase 1, cytosolic	identical protein binding	Molecular function	-
DERL1	79139	derlin 1	ER-associated ubiquitin-dependent protein catabolic process	Biological process	22013210
CACNA1F	778	calcium channel, voltage-dependent, L type, alpha 1F subunit	high voltage-gated calcium channel activity	Molecular function	-
ANKDD1A	348094	ankyrin repeat and death domain containing 1A	signal transduction	Biological process	-
PIK3CD	5293	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	natural killer cell differentiation	Biological process	20940048
WIPI1	55062	WD repeat domain, phosphoinositide interacting 1	IRE1-mediated unfolded protein response	Biological process	-
CDC40	51362	cell division cycle 40	transcription from RNA polymerase II promoter	Biological process	-
CHIT1	1118	chitinase 1 (chitotriosidase)	extracellular space	Cellular component	19725875
STXBP3	6814	syntaxin binding protein 3	specific granule	Cellular component	18588921
PAK4	10298	p21 protein (Cdc42/Rac)-activated kinase 4	focal adhesion	Cellular component	21423176
SKI	6497	SKI proto-oncogene	cell motility	Biological process	14583455
AKR1C1	1645	aldo-keto reductase family 1, member C1	protein homooligomerization	Biological process	8486699
FYN	2534	FYN proto-oncogene, Src family tyrosine kinase	ephrin receptor binding	Molecular function	10498895
FOXK1	221937	forkhead box K1	nucleus	Cellular component	-
ZNF93	81931	zinc finger protein 93	zinc ion binding	Molecular function	2023909
MUC21	394263	mucin 21, cell surface associated	integral component of membrane	Cellular component	-
PFDN5	5204	prefoldin subunit 5	retina development in camera-type eye	Biological process	-
GIMAP2	26157	GTPase, IMAP family member 2	GTP binding	Molecular function	-
PVRL1	5818	poliovirus receptor-related 1 (herpesvirus entry mediator C)	cell junction assembly	Biological process	-
ITGA6	3655	integrin, alpha 6	leukocyte migration	Biological process	-
AMOTL1	154810	angiomotin like 1	cytosol	Cellular component	-
CACNA1G	8913	calcium channel, voltage-dependent, T type, alpha 1G subunit	ion transmembrane transport	Biological process	-
MTM1	4534	myotubularin 1	mitochondrion distribution	Biological process	21135508
TLE6	79816	transducin-like enhancer of split 6	nucleus	Cellular component	-
ARL8A	127829	ADP-ribosylation factor-like 8A	beta-tubulin binding	Molecular function	15331635
PSD3	23362	pleckstrin and Sec7 domain containing 3	trans-Golgi network	Cellular component	-
TIPARP	25976	TCDD-inducible poly(ADP-ribose) polymerase	face morphogenesis	Biological process	-
EIF2AK2	5610	eukaryotic translation initiation factor 2-alpha kinase 2	evasion or tolerance by virus of host immune response	Biological process	-
NDEL1	81565	nudE neurodevelopment protein 1-like 1	cytosol	Cellular component	-
RPL37AP8	644338	ribosomal protein L37a pseudogene 8	structural constituent of ribosome	Molecular function	-
VSTM4	196740	V-set and transmembrane domain containing 4	plasma membrane	Cellular component	-
SPRY4	81848	sprouty homolog 4 (Drosophila)	protein binding	Molecular function	12027893
MAP3K14	9020	mitogen-activated protein kinase kinase kinase 14	innate immune response	Biological process	-
RPS4X	6191	ribosomal protein S4, X-linked	cellular protein metabolic process	Biological process	-
GUCY1B3	2983	guanylate cyclase 1, soluble, beta 3	metal ion binding	Molecular function	-
IL1B	3553	interleukin 1, beta	regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	10748004
CYB5A	1528	cytochrome b5 type A (microsomal)	small molecule metabolic process	Biological process	-
FBXO43	286151	F-box protein 43	negative regulation of meiotic nuclear division	Biological process	-
NFKB1	4790	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	24434510
WNT10A	80326	wingless-type MMTV integration site family, member 10A	proteinaceous extracellular matrix	Cellular component	-
LRP1	4035	low density lipoprotein receptor-related protein 1	apolipoprotein binding	Molecular function	18635818
CELSR2	1952	cadherin, EGF LAG seven-pass G-type receptor 2	homophilic cell adhesion via plasma membrane adhesion molecules	Biological process	-
NDNF	79625	neuron-derived neurotrophic factor	extracellular matrix	Cellular component	-
RNF139	11236	ring finger protein 139	ubiquitin-like protein transferase activity	Molecular function	17016439
OR4F4	26682	olfactory receptor, family 4, subfamily F, member 4	olfactory receptor activity	Molecular function	-
TYRO3	7301	TYRO3 protein tyrosine kinase	spermatogenesis	Biological process	-
LGI1	9211	leucine-rich, glioma inactivated 1	nervous system development	Biological process	9879993
GSTM1	2944	glutathione S-transferase mu 1	xenobiotic metabolic process	Biological process	-
ZNF486	90649	zinc finger protein 486	nucleus	Cellular component	-
TSC1	7248	tuberous sclerosis 1	cell cortex	Cellular component	10806479
SLC1A1	6505	solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1	cysteine transport	Biological process	21123949
IGF1	3479	insulin-like growth factor 1 (somatomedin C)	cellular protein metabolic process	Biological process	-
HAO1	54363	hydroxyacid oxidase (glycolate oxidase) 1	cellular nitrogen compound metabolic process	Biological process	-
ACTR8	93973	ARP8 actin-related protein 8 homolog (yeast)	DNA repair	Biological process	-
DACT2	168002	dishevelled-binding antagonist of beta-catenin 2	protein kinase A binding	Molecular function	-
FREM1	158326	FRAS1 related extracellular matrix 1	integral component of membrane	Cellular component	-
RRAGD	58528	Ras-related GTP binding D	metabolic process	Biological process	-
HDAC8	55869	histone deacetylase 8	mitotic cell cycle	Biological process	-
RBL2	5934	retinoblastoma-like 2	transcription factor complex	Cellular component	-
FHL1	2273	four and a half LIM domains 1	ion channel binding	Molecular function	18281375
TAOK1	57551	TAO kinase 1	protein binding	Molecular function	11733138
CSDE1	7812	cold shock domain containing E1, RNA-binding	Golgi apparatus	Cellular component	-
HIST2H2AA3	8337	histone cluster 2, H2aa3	DNA binding	Molecular function	-
FOXJ2	55810	forkhead box J2	sequence-specific DNA binding	Molecular function	10777590
PVRL2	5819	poliovirus receptor-related 2 (herpesvirus entry mediator B)	cell-cell junction	Cellular component	9845526
SEC31A	22872	SEC31 homolog A (S. cerevisiae)	antigen processing and presentation of exogenous peptide antigen via MHC class II	Biological process	-
IRF7	3665	interferon regulatory factor 7	interferon-beta production	Biological process	-
AURKA	6790	aurora kinase A	germinal vesicle	Cellular component	-
JPH3	57338	junctophilin 3	plasma membrane	Cellular component	-
PER2	8864	period circadian clock 2	negative regulation of protein ubiquitination	Biological process	-
RARA	5914	retinoic acid receptor, alpha	prostate gland development	Biological process	-
NHS	4810	Nance-Horan syndrome (congenital cataracts and dental anomalies)	lens development in camera-type eye	Biological process	-
ITM2B	9445	integral membrane protein 2B	integral component of organelle membrane	Cellular component	10526337
TRMT12	55039	tRNA methyltransferase 12 homolog (S. cerevisiae)	protein binding	Molecular function	25416956
DPP4	1803	dipeptidyl-peptidase 4	regulation of cell-cell adhesion mediated by integrin	Biological process	11772392
NCOA6	23054	nuclear receptor coactivator 6	cellular response to DNA damage stimulus	Biological process	17500065
PSMD11	5717	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	membrane	Cellular component	19946888
WBP2	23558	WW domain binding protein 2	positive regulation of gene expression, epigenetic	Biological process	23233354
ALKBH7	84266	alkB, alkylation repair homolog 7 (E. coli)	cellular response to DNA damage stimulus	Biological process	23666923
WNT1	7471	wingless-type MMTV integration site family, member 1	positive regulation of Notch signaling pathway	Biological process	16501043
NRP1	8829	neuropilin 1	growth cone	Cellular component	-
ELFN1	392617	extracellular leucine-rich repeat and fibronectin type III domain containing 1	synapse organization	Biological process	-
RIMS1	22999	regulating synaptic membrane exocytosis 1	visual perception	Biological process	-
LCK	3932	LCK proto-oncogene, Src family tyrosine kinase	protein C-terminus binding	Molecular function	16245368
MYO6	4646	myosin VI	filamentous actin	Cellular component	-
SMC5	23137	structural maintenance of chromosomes 5	cellular senescence	Biological process	17589526
SHROOM4	57477	shroom family member 4	stress fiber	Cellular component	-
CASP8AP2	9994	caspase 8 associated protein 2	regulation of transcription, DNA-templated	Biological process	-
UBL4A	8266	ubiquitin-like 4A	cytosol	Cellular component	20676083
LAMC3	10319	laminin, gamma 3	membrane	Cellular component	10225960
FZD7	8324	frizzled class receptor 7	stem cell maintenance	Biological process	18681827
PSAT1	29968	phosphoserine aminotransferase 1	O-phospho-L-serine:2-oxoglutarate aminotransferase activity	Molecular function	-
COASY	80347	CoA synthase	phosphorylation	Biological process	-
UGT1A1	54658	UDP glucuronosyltransferase 1 family, polypeptide A1	biphenyl catabolic process	Biological process	-
PSMD2	5708	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	protein binding	Molecular function	11278995
WAC	51322	WW domain containing adaptor with coiled-coil	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	Biological process	22354037
COPS2	9318	COP9 signalosome subunit 2	COP9 signalosome	Cellular component	18850735
OTP	23440	orthopedia homeobox	positive regulation of neuroblast proliferation	Biological process	-
AKT1	207	v-akt murine thymoma viral oncogene homolog 1	transcription initiation from RNA polymerase II promoter	Biological process	-
ATP2B4	493	ATPase, Ca++ transporting, plasma membrane 4	Z disc	Cellular component	19287093
PPARD	5467	peroxisome proliferator-activated receptor delta	cell proliferation	Biological process	11847022
NR4A3	8013	nuclear receptor subfamily 4, group A, member 3	DNA binding	Molecular function	8634690
RRAS	6237	related RAS viral (r-ras) oncogene homolog	focal adhesion	Cellular component	21423176
KLHL8	57563	kelch-like family member 8	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	19158078
TMX1	81542	thioredoxin-related transmembrane protein 1	oxidation-reduction process	Biological process	-
NCBP2	22916	nuclear cap binding protein subunit 2, 20kDa	gene expression	Biological process	-
GSTK1	373156	glutathione S-transferase kappa 1	peroxisome	Cellular component	14742434
MAPK8	5599	mitogen-activated protein kinase 8	enzyme binding	Molecular function	14615289
PAX2	5076	paired box 2	metanephric collecting duct development	Biological process	-
MYH11	4629	myosin, heavy chain 11, smooth muscle	muscle contraction	Biological process	-
PSMD12	5718	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	regulation of cellular amino acid metabolic process	Biological process	-
IDO1	3620	indoleamine 2,3-dioxygenase 1	electron carrier activity	Molecular function	2109605
CD96	10225	CD96 molecule	cell adhesion	Biological process	-
AGTRAP	57085	angiotensin II receptor-associated protein	cell cortex	Cellular component	-
DCP1B	196513	decapping mRNA 1B	deadenylation-dependent decapping of nuclear-transcribed mRNA	Biological process	-
DTNBP1	84062	dystrobrevin binding protein 1	cell junction	Cellular component	-
CDS2	8760	CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2	integral component of membrane	Cellular component	-
CPLX1	10815	complexin 1	synaptic transmission	Biological process	-
T	6862	T, brachyury homolog (mouse)	heart morphogenesis	Biological process	21632880
GRPR	2925	gastrin-releasing peptide receptor	bombesin receptor signaling pathway	Biological process	-
PPP2CA	5515	protein phosphatase 2, catalytic subunit, alpha isozyme	protein dimerization activity	Molecular function	-
ZP1	22917	zona pellucida glycoprotein 1 (sperm receptor)	extracellular region	Cellular component	-
KLC1	3831	kinesin light chain 1	small GTPase mediated signal transduction	Biological process	-
ALOX5	240	arachidonate 5-lipoxygenase	leukotriene metabolic process	Biological process	-
TM2D1	83941	TM2 domain containing 1	G-protein coupled receptor signaling pathway	Biological process	-
GAS2L3	283431	growth arrest-specific 2 like 3	microtubule binding	Molecular function	21561867
PPIAL4G	644591	peptidylprolyl isomerase A (cyclophilin A)-like 4G	cytoplasm	Cellular component	-
CDK5RAP2	55755	CDK5 regulatory subunit associated protein 2	centrosome	Cellular component	-
ABCF2	10061	ATP-binding cassette, sub-family F (GCN20), member 2	ATP-binding cassette (ABC) transporter complex	Cellular component	9878413
ZFP36L2	678	ZFP36 ring finger protein-like 2	regulation of mRNA stability	Biological process	-
HLA-DRB5	3127	major histocompatibility complex, class II, DR beta 5	endocytic vesicle membrane	Cellular component	-
TSPAN5	10098	tetraspanin 5	integral component of membrane	Cellular component	-
NANOS2	339345	nanos homolog 2 (Drosophila)	cytoplasmic mRNA processing body	Cellular component	-
OXT	5020	oxytocin/neurophysin I prepropeptide	sleep	Biological process	-
NF1	4763	neurofibromin 1	negative regulation of cell-matrix adhesion	Biological process	-
RDH13	112724	retinol dehydrogenase 13 (all-trans/9-cis)	eye photoreceptor cell development	Biological process	-
HTR6	3362	5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled	serotonin receptor signaling pathway	Biological process	-
IGF2BP1	10642	insulin-like growth factor 2 mRNA binding protein 1	CRD-mediated mRNA stabilization	Biological process	19029303
RHCE	6006	Rh blood group, CcEe antigens	ammonium transmembrane transporter activity	Molecular function	-
SQSTM1	8878	sequestosome 1	cytoplasm	Cellular component	20168092
SKAP2	8935	src kinase associated phosphoprotein 2	SH3/SH2 adaptor activity	Molecular function	9671755
GK5	256356	glycerol kinase 5 (putative)	triglyceride metabolic process	Biological process	-
PHF20	51230	PHD finger protein 20	histone H4-K16 acetylation	Biological process	20018852
CER1	9350	cerberus 1, DAN family BMP antagonist	negative regulation of cell proliferation	Biological process	10049596
FLT3	2322	fms-related tyrosine kinase 3	response to organonitrogen compound	Biological process	-
STS	412	steroid sulfatase (microsomal), isozyme S	glycosphingolipid metabolic process	Biological process	-
CCR5	1234	chemokine (C-C motif) receptor 5 (gene/pseudogene)	chemotaxis	Biological process	10741397
SLC39A1	27173	solute carrier family 39 (zinc transporter), member 1	receptor binding	Molecular function	-
POLR2B	5431	polymerase (RNA) II (DNA directed) polypeptide B, 140kDa	RNA splicing	Biological process	-
LIMS2	55679	LIM and senescent cell antigen-like domains 2	protein binding	Molecular function	25416956
ELF3	1999	E74-like factor 3 (ets domain transcription factor, epithelial-specific )	extracellular matrix organization	Biological process	-
PRPSAP1	5635	phosphoribosyl pyrophosphate synthetase-associated protein 1	magnesium ion binding	Molecular function	-
ACTR3	10096	ARP3 actin-related protein 3 homolog (yeast)	actin filament	Cellular component	-
ZNF551	90233	zinc finger protein 551	DNA binding	Molecular function	-
NOP14	8602	NOP14 nucleolar protein	maturation of SSU-rRNA	Biological process	-
FASTKD1	79675	FAST kinase domains 1	protein phosphorylation	Biological process	-
ARHGAP4	393	Rho GTPase activating protein 4	small GTPase mediated signal transduction	Biological process	-
MEPE	56955	matrix extracellular phosphoglycoprotein	negative regulation of bone mineralization	Biological process	-
ADAM33	80332	ADAM metallopeptidase domain 33	integral component of membrane	Cellular component	11814695
CNGA3	1261	cyclic nucleotide gated channel alpha 3	response to magnesium ion	Biological process	-
DLD	1738	dihydrolipoamide dehydrogenase	cellular nitrogen compound metabolic process	Biological process	-
IGFALS	3483	insulin-like growth factor binding protein, acid labile subunit	extracellular region	Cellular component	-
SPAG16	79582	sperm associated antigen 16	nucleus	Cellular component	-
SP140	11262	SP140 nuclear body protein	chromatin remodeling	Biological process	-
ZIC3	7547	Zic family member 3	determination of left/right symmetry	Biological process	9354794
RPS2	6187	ribosomal protein S2	membrane	Cellular component	19946888
PARK7	11315	parkinson protein 7	negative regulation of extrinsic apoptotic signaling pathway	Biological process	21785459
ITPKA	3706	inositol-trisphosphate 3-kinase A	calmodulin-dependent protein kinase activity	Molecular function	-
NLK	51701	nemo-like kinase	SH2 domain binding	Molecular function	-
ITGA1	3672	integrin, alpha 1	focal adhesion	Cellular component	11518510
DNMT3A	1788	DNA (cytosine-5-)-methyltransferase 3 alpha	euchromatin	Cellular component	12138111
MYT1L	23040	myelin transcription factor 1-like	DNA binding	Molecular function	-
TPR	7175	translocated promoter region, nuclear basket protein	mitotic cell cycle	Biological process	-
CD4	920	CD4 molecule	enzyme binding	Molecular function	19333378
VIPAS39	63894	VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog	transcription, DNA-templated	Biological process	-
GPNMB	10457	glycoprotein (transmembrane) nmb	bone mineralization	Biological process	-
PRKCA	5578	protein kinase C, alpha	chondrocyte differentiation	Biological process	-
PSMA4	5685	proteasome (prosome, macropain) subunit, alpha type, 4	stimulatory C-type lectin receptor signaling pathway	Biological process	-
EVX2	344191	even-skipped homeobox 2	sequence-specific DNA binding	Molecular function	-
JOSD2	126119	Josephin domain containing 2	protein deubiquitination	Biological process	21118805
B3GNT3	10331	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3	keratan sulfate biosynthetic process	Biological process	-
HADHB	3032	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit	extracellular exosome	Cellular component	23376485
PRMT5	10419	protein arginine methyltransferase 5	spliceosomal snRNP assembly	Biological process	-
ADORA2B	136	adenosine A2b receptor	activation of MAPK activity	Biological process	10101031
POLR3B	55703	polymerase (RNA) III (DNA directed) polypeptide B	DNA-directed RNA polymerase III complex	Cellular component	24107381
MANF	7873	mesencephalic astrocyte-derived neurotrophic factor	biological_process	Biological process	-
DBNL	28988	drebrin-like	synapse assembly	Biological process	-
FOXC1	2296	forkhead box C1	negative regulation of angiogenesis	Biological process	-
RAPGEF3	10411	Rap guanine nucleotide exchange factor (GEF) 3	regulation of actin cytoskeleton reorganization	Biological process	21840392
NYNRIN	57523	NYN domain and retroviral integrase containing	cellular_component	Cellular component	-
TLR5	7100	toll-like receptor 5	toll-like receptor signaling pathway	Biological process	-
MAPKAPK3	7867	mitogen-activated protein kinase-activated protein kinase 3	toll-like receptor 5 signaling pathway	Biological process	-
USP47	55031	ubiquitin specific peptidase 47	base-excision repair	Biological process	21362556
DEF6	50619	differentially expressed in FDCP 6 homolog (mouse)	cytoplasm	Cellular component	-
SOBP	55084	sine oculis binding protein homolog (Drosophila)	SUMO polymer binding	Molecular function	23086935
NDFIP1	80762	Nedd4 family interacting protein 1	negative regulation of T cell proliferation	Biological process	-
PNPLA3	80339	patatin-like phospholipase domain containing 3	triglyceride acyl-chain remodeling	Biological process	24511104
C5AR1	728	complement component 5a receptor 1	cellular defense response	Biological process	8779720
MSI1	4440	musashi RNA-binding protein 1	response to hormone	Biological process	-
ELN	2006	elastin	extracellular matrix disassembly	Biological process	-
METTL13	51603	methyltransferase like 13	methyltransferase activity	Molecular function	-
PRPF3	9129	pre-mRNA processing factor 3	cytoplasm	Cellular component	-
PHF5A	84844	PHD finger protein 5A	transcription, DNA-templated	Biological process	-
PRKG1	5592	protein kinase, cGMP-dependent, type I	plasma membrane	Cellular component	16990611
PRKCH	5583	protein kinase C, eta	positive regulation of keratinocyte differentiation	Biological process	-
TBC1D8	11138	TBC1 domain family, member 8 (with GRAM domain)	regulation of cilium assembly	Biological process	17646400
RSPO1	284654	R-spondin 1	regulation of gene expression	Biological process	-
SLC35E2	9906	solute carrier family 35, member E2	anion transmembrane transport	Biological process	-
FGFR1	2260	fibroblast growth factor receptor 1	cytosol	Cellular component	-
LSM5	23658	LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)	nucleus	Cellular component	10369684
CDON	50937	cell adhesion associated, oncogene regulated	positive regulation of small GTPase mediated signal transduction	Biological process	-
SUN2	25777	Sad1 and UNC84 domain containing 2	LINC complex	Cellular component	18396275
MYO3B	140469	myosin IIIB	photoreceptor inner segment	Cellular component	-
TIMP2	7077	TIMP metallopeptidase inhibitor 2	proteinaceous extracellular matrix	Cellular component	-
PITX2	5308	paired-like homeodomain 2	Wnt signaling pathway	Biological process	-
PML	5371	promyelocytic leukemia	protein targeting	Biological process	15195100
MAPKAPK3	7867	mitogen-activated protein kinase-activated protein kinase 3	mitogen-activated protein kinase binding	Molecular function	-
OSBPL8	114882	oxysterol binding protein-like 8	membrane	Cellular component	19946888
ALYREF	10189	Aly/REF export factor	cytosol	Cellular component	-
C19orf12	83636	chromosome 19 open reading frame 12	endoplasmic reticulum	Cellular component	23857908
REN	5972	renin	kidney development	Biological process	16116425
PIM2	11040	Pim-2 proto-oncogene, serine/threonine kinase	protein stabilization	Biological process	-
CCKBR	887	cholecystokinin B receptor	integral component of plasma membrane	Cellular component	10913157
TOP3B	8940	topoisomerase (DNA) III beta	condensed chromosome	Cellular component	-
GRWD1	83743	glutamate-rich WD repeat containing 1	nucleus	Cellular component	-
GUSB	2990	glucuronidase, beta	beta-glucuronidase activity	Molecular function	-
ENO3	2027	enolase 3 (beta, muscle)	cytosol	Cellular component	-
TBKBP1	9755	TBK1 binding protein 1	protein binding	Molecular function	14743216
DNAH1	25981	dynein, axonemal, heavy chain 1	dynein complex	Cellular component	8812413
NEFM	4741	neurofilament, medium polypeptide	regulation of axon diameter	Biological process	-
TXNDC9	10190	thioredoxin domain containing 9	cellular_component	Cellular component	-
KCNQ4	9132	potassium channel, voltage gated KQT-like subfamily Q, member 4	potassium ion transmembrane transport	Biological process	-
ITGAX	3687	integrin, alpha X (complement component 3 receptor 4 subunit)	integrin complex	Cellular component	-
ZNF410	57862	zinc finger protein 410	transcription, DNA-templated	Biological process	-
PSEN1	5663	presenilin 1	positive regulation of MAP kinase activity	Biological process	-
HGS	9146	hepatocyte growth factor-regulated tyrosine kinase substrate	early endosome membrane	Cellular component	-
RPL41	6171	ribosomal protein L41	viral process	Biological process	-
RNF26	79102	ring finger protein 26	zinc ion binding	Molecular function	11352657
UROS	7390	uroporphyrinogen III synthase	cellular response to amine stimulus	Biological process	-
EFNA1	1942	ephrin-A1	regulation of blood vessel endothelial cell migration	Biological process	-
MMP9	4318	matrix metallopeptidase 9	endopeptidase activity	Molecular function	19022250
TFAP4	7023	transcription factor AP-4 (activating enhancer binding protein 4)	positive regulation by host of viral transcription	Biological process	2833704
GDI2	2665	GDP dissociation inhibitor 2	vesicle-mediated transport	Biological process	-
LTA	4049	lymphotoxin alpha	extracellular space	Cellular component	-
PLRG1	5356	pleiotropic regulator 1	protein localization to nucleus	Biological process	-
SEC23A	10484	Sec23 homolog A (S. cerevisiae)	membrane organization	Biological process	-
SLC1A1	6505	solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1	neurotransmitter secretion	Biological process	-
SUMO3	6612	small ubiquitin-like modifier 3	cytoplasm	Cellular component	-
SLC39A5	283375	solute carrier family 39 (zinc transporter), member 5	BMP signaling pathway	Biological process	24891338
CDO1	1036	cysteine dioxygenase type 1	sulfur amino acid metabolic process	Biological process	-
SULT2B1	6820	sulfotransferase family, cytosolic, 2B, member 1	endoplasmic reticulum	Cellular component	-
AIF1	199	allograft inflammatory factor 1	cytosol	Cellular component	22116621
SREK1	140890	splicing regulatory glutamine/lysine-rich protein 1	RNA splicing	Biological process	-
SH3BP5	9467	SH3-domain binding protein 5 (BTK-associated)	mitochondrion	Cellular component	-
MRPS28	28957	mitochondrial ribosomal protein S28	mitochondrion	Cellular component	-
PLA2R1	22925	phospholipase A2 receptor 1, 180kDa	positive regulation of DNA damage response, signal transduction by p53 class mediator	Biological process	19197340
NLGN4X	57502	neuroligin 4, X-linked	integral component of membrane	Cellular component	16377159
SFRP2	6423	secreted frizzled-related protein 2	negative regulation of epithelial to mesenchymal transition	Biological process	19095296
HS3ST1	9957	heparan sulfate (glucosamine) 3-O-sulfotransferase 1	integral component of membrane	Cellular component	9988767
EGLN1	54583	egl-9 family hypoxia-inducible factor 1	negative regulation of cAMP catabolic process	Biological process	-
IQSEC2	23096	IQ motif and Sec7 domain 2	positive regulation of GTPase activity	Biological process	-
TBC1D2	55357	TBC1 domain family, member 2	cytoplasmic membrane-bounded vesicle	Cellular component	-
RARA	5914	retinoic acid receptor, alpha	response to vitamin A	Biological process	-
CEP57	9702	centrosomal protein 57kDa	cytosol	Cellular component	-
B3GALTL	145173	beta 1,3-galactosyltransferase-like	protein O-linked glycosylation	Biological process	-
SLIT3	6586	slit homolog 3 (Drosophila)	negative regulation of gene expression	Biological process	-
POMC	5443	proopiomelanocortin	regulation of appetite	Biological process	9620771
A4GNT	51146	alpha-1,4-N-acetylglucosaminyltransferase	negative regulation of epithelial cell proliferation	Biological process	-
RIPPLY1	92129	ripply transcriptional repressor 1	nucleus	Cellular component	-
TAF6L	10629	TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa	chromatin organization	Biological process	-
DOHH	83475	deoxyhypusine hydroxylase/monooxygenase	post-translational protein modification	Biological process	-
FOXN4	121643	forkhead box N4	chromatin binding	Molecular function	22323600
ANXA1	301	annexin A1	focal adhesion	Cellular component	21423176
SUZ12	23512	SUZ12 polycomb repressive complex 2 subunit	sex chromatin	Cellular component	-
MMP26	56547	matrix metallopeptidase 26	metalloendopeptidase activity	Molecular function	-
HOXC13	3229	homeobox C13	chromatin binding	Molecular function	-
CLTB	1212	clathrin, light chain B	intracellular membrane-bounded organelle	Cellular component	-
STRADA	92335	STE20-related kinase adaptor alpha	signal transduction by protein phosphorylation	Biological process	-
PSMA7	5688	proteasome (prosome, macropain) subunit, alpha type, 7	viral process	Biological process	-
CNTNAP1	8506	contactin associated protein 1	signal transduction	Biological process	9118959
APOBEC1	339	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	mRNA modification	Biological process	-
HRAS	3265	Harvey rat sarcoma viral oncogene homolog	positive regulation of transcription from RNA polymerase II promoter	Biological process	22065586
OR52K1	390036	olfactory receptor, family 52, subfamily K, member 1	G-protein coupled receptor signaling pathway	Biological process	-
CNOT11	55571	CCR4-NOT transcription complex, subunit 11	protein binding	Molecular function	23232451
SRI	6717	sorcin	action potential	Biological process	9668070
ARFGEF2	10564	ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)	protein binding	Molecular function	10716990
CTSL	1514	cathepsin L	protein binding	Molecular function	12504904
PRKCQ	5588	protein kinase C, theta	positive regulation of T-helper 17 type immune response	Biological process	-
IL4	3565	interleukin 4	negative regulation of extrinsic apoptotic signaling pathway	Biological process	-
HEBP2	23593	heme binding protein 2	positive regulation of necrotic cell death	Biological process	17098234
PRKAA1	5562	protein kinase, AMP-activated, alpha 1 catalytic subunit	cellular response to glucose starvation	Biological process	-
GHRHR	2692	growth hormone releasing hormone receptor	cell surface	Cellular component	1333056
COL19A1	1310	collagen, type XIX, alpha 1	collagen trimer	Cellular component	7775380
SQSTM1	8878	sequestosome 1	positive regulation of protein phosphorylation	Biological process	-
PKN1	5585	protein kinase N1	cleavage furrow	Cellular component	17332740
LPA	4018	lipoprotein, Lp(a)	proteolysis involved in cellular protein catabolic process	Biological process	-
ST3GAL6	10402	ST3 beta-galactoside alpha-2,3-sialyltransferase 6	keratan sulfate biosynthetic process	Biological process	-
MAPK3	5595	mitogen-activated protein kinase 3	phosphorylation	Biological process	15950189
SEMA3F	6405	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	negative chemotaxis	Biological process	-
YME1L1	10730	YME1-like 1 ATPase	integral component of membrane	Cellular component	-
HES1	3280	hes family bHLH transcription factor 1	cochlea development	Biological process	-
NT5C3A	51251	5'-nucleotidase, cytosolic IIIA	nucleobase-containing small molecule metabolic process	Biological process	-
DYRK1A	1859	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	non-membrane spanning protein tyrosine kinase activity	Molecular function	9748265
RTP2	344892	receptor (chemosensory) transporter protein 2	protein insertion into membrane	Biological process	15550249
CNIH1	10175	cornichon family AMPA receptor auxiliary protein 1	intracellular signal transduction	Biological process	-
IKBKG	8517	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	I-kappaB kinase/NF-kappaB signaling	Biological process	18626576
TLR1	7096	toll-like receptor 1	inflammatory response	Biological process	-
EPHB4	2050	EPH receptor B4	ATP binding	Molecular function	-
CRELD2	79174	cysteine-rich with EGF-like domains 2	extracellular space	Cellular component	-
POLR2K	5440	polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa	transcription from RNA polymerase II promoter	Biological process	-
RPL18	6141	ribosomal protein L18	viral transcription	Biological process	-
PF4	5196	platelet factor 4	CXCR3 chemokine receptor binding	Molecular function	12782716
RAB42	115273	RAB42, member RAS oncogene family	GTP binding	Molecular function	-
AMOT	154796	angiomotin	chemotaxis	Biological process	-
C22orf23	84645	chromosome 22 open reading frame 23	cellular_component	Cellular component	-
FSTL3	10272	follistatin-like 3 (secreted glycoprotein)	extracellular space	Cellular component	16150905
RHOU	58480	ras homolog family member U	GTPase activity	Molecular function	-
ZNF205	7755	zinc finger protein 205	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	Biological process	22306510
DDX3X	1654	DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked	ATP-dependent RNA helicase activity	Molecular function	21589879
HAX1	10456	HCLS1 associated protein X-1	positive regulation of actin cytoskeleton reorganization	Biological process	23001182
SULF2	55959	sulfatase 2	endoplasmic reticulum	Cellular component	18687675
P2RX2	22953	purinergic receptor P2X, ligand gated ion channel, 2	sensory perception of sound	Biological process	23345450
JAGN1	84522	jagunal homolog 1 (Drosophila)	neutrophil differentiation	Biological process	25129144
ZNF888	388559	zinc finger protein 888	transcription, DNA-templated	Biological process	-
SRD5A2	6716	steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)	response to nutrient levels	Biological process	-
PALLD	23022	palladin, cytoskeletal associated protein	Z disc	Cellular component	-
RNF8	9025	ring finger protein 8, E3 ubiquitin protein ligase	double-strand break repair via nonhomologous end joining	Biological process	-
IMPDH1	3614	IMP (inosine 5'-monophosphate) dehydrogenase 1	DNA binding	Molecular function	14766016
COMT	1312	catechol-O-methyltransferase	small molecule metabolic process	Biological process	-
TAT	6898	tyrosine aminotransferase	2-oxoglutarate metabolic process	Biological process	7999802
CDKL1	8814	cyclin-dependent kinase-like 1 (CDC2-related kinase)	cytoplasm	Cellular component	-
KIRREL	55243	kin of IRRE like (Drosophila)	plasma membrane	Cellular component	-
GCK	2645	glucokinase (hexokinase 4)	negative regulation of gluconeogenesis	Biological process	8878425
GTF2H4	2968	general transcription factor IIH, polypeptide 4, 52kDa	DNA repair	Biological process	-
PSMC3	5702	proteasome (prosome, macropain) 26S subunit, ATPase, 3	small molecule metabolic process	Biological process	-
RAB2A	5862	RAB2A, member RAS oncogene family	mitotic cell cycle	Biological process	-
HNRNPA2B1	3181	heterogeneous nuclear ribonucleoprotein A2/B1	gene expression	Biological process	-
PPP1R3C	5507	protein phosphatase 1, regulatory subunit 3C	dephosphorylation	Biological process	8985175
ABCF2	10061	ATP-binding cassette, sub-family F (GCN20), member 2	transport	Biological process	9878413
TAS2R46	259292	taste receptor, type 2, member 46	G-protein coupled receptor signaling pathway	Biological process	-
SCAMP1	9522	secretory carrier membrane protein 1	integral component of membrane	Cellular component	15840657
SERPINB3	6317	serpin peptidase inhibitor, clade B (ovalbumin), member 3	negative regulation of proteolysis	Biological process	12975381
CTTN	2017	cortactin	focal adhesion	Cellular component	21423176
RELA	5970	v-rel avian reticuloendotheliosis viral oncogene homolog A	cellular response to peptide hormone stimulus	Biological process	22357537
PDGFRA	5156	platelet-derived growth factor receptor, alpha polypeptide	estrogen metabolic process	Biological process	-
ZNF177	7730	zinc finger protein 177	negative regulation of transcription from RNA polymerase II promoter	Biological process	8661005
SKIL	6498	SKI-like proto-oncogene	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	Biological process	-
ARSD	414	arylsulfatase D	sphingolipid metabolic process	Biological process	-
TIAL1	7073	TIA1 cytotoxic granule-associated RNA binding protein-like 1	lysosome	Cellular component	1326761
ITGAM	3684	integrin, alpha M (complement component 3 receptor 3 subunit)	protein heterodimerization activity	Molecular function	-
EHD2	30846	EH-domain containing 2	endocytic recycling	Biological process	17233914
CD3D	915	CD3d molecule, delta (CD3-TCR complex)	T cell costimulation	Biological process	-
BIRC8	112401	baculoviral IAP repeat containing 8	protein ubiquitination	Biological process	-
PGS1	9489	phosphatidylglycerophosphate synthase 1	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity	Molecular function	-
LAMP3	27074	lysosomal-associated membrane protein 3	alveolar lamellar body membrane	Cellular component	-
SNAI1	6615	snail family zinc finger 1	regulation of bicellular tight junction assembly	Biological process	15314165
IGBP1	3476	immunoglobulin (CD79A) binding protein 1	negative regulation of protein dephosphorylation	Biological process	-
UQCRC1	7384	ubiquinol-cytochrome c reductase core protein I	mitochondrial electron transport, ubiquinol to cytochrome c	Biological process	-
NOX1	27035	NADPH oxidase 1	cellular stress response to acidic pH	Biological process	10615049
CENPB	1059	centromere protein B, 80kDa	chromosome	Cellular component	2022189
FLRT3	23767	fibronectin leucine rich transmembrane protein 3	negative chemotaxis	Biological process	-
BRCA1	672	breast cancer 1, early onset	androgen receptor signaling pathway	Biological process	15572661
SERPINI2	5276	serpin peptidase inhibitor, clade I (pancpin), member 2	extracellular space	Cellular component	-
BIRC5	332	baculoviral IAP repeat containing 5	G2/M transition of mitotic cell cycle	Biological process	9859993
RFXAP	5994	regulatory factor X-associated protein	positive regulation of transcription, DNA-templated	Biological process	-
DPEP1	1800	dipeptidase 1 (renal)	protein binding	Molecular function	16189514
ATG14	22863	autophagy related 14	nucleus	Cellular component	-
P2RX1	5023	purinergic receptor P2X, ligand gated ion channel, 1	serotonin secretion by platelet	Biological process	-
SIAH1	6477	siah E3 ubiquitin protein ligase 1	cytosol	Cellular component	-
EGF	1950	epidermal growth factor	lysosomal membrane	Cellular component	17897319
ZNF510	22869	zinc finger protein 510	nucleus	Cellular component	-
EYA1	2138	EYA transcriptional coactivator and phosphatase 1	establishment or maintenance of apical/basal cell polarity	Biological process	-
ERO1L	30001	ERO1-like (S. cerevisiae)	oxidation-reduction process	Biological process	-
CXCR1	3577	chemokine (C-X-C motif) receptor 1	chemokine receptor activity	Molecular function	1840701
STAR	6770	steroidogenic acute regulatory protein	regulation of steroid biosynthetic process	Biological process	-
ERF	2077	Ets2 repressor factor	cell differentiation	Biological process	-
TMEM59	9528	transmembrane protein 59	endopeptidase activity	Molecular function	-
TKFC	26007	triokinase/FMN cyclase	nucleus	Cellular component	21630459
CEACAM7	1087	carcinoembryonic antigen-related cell adhesion molecule 7	integral component of membrane	Cellular component	7806520
IFNG	3458	interferon, gamma	apoptotic process	Biological process	7828849
CD19	930	CD19 molecule	plasma membrane	Cellular component	-
ASXL1	171023	additional sex combs like transcriptional regulator 1	retinoic acid receptor binding	Molecular function	-
PMS1	5378	PMS1 postmeiotic segregation increased 1 (S. cerevisiae)	single-stranded DNA binding	Molecular function	-
SREBF1	6720	sterol regulatory element binding transcription factor 1	response to drug	Biological process	-
NOV	4856	nephroblastoma overexpressed	cell-cell signaling	Biological process	-
TJAP1	93643	tight junction associated protein 1 (peripheral)	trans-Golgi network	Cellular component	-
PSEN1	5663	presenilin 1	negative regulation of neuron apoptotic process	Biological process	-
NUBPL	80224	nucleotide binding protein-like	mitochondrial respiratory chain complex I assembly	Biological process	19752196
SPTB	6710	spectrin, beta, erythrocytic	actin cytoskeleton	Cellular component	10950304
NMT1	4836	N-myristoyltransferase 1	glycylpeptide N-tetradecanoyltransferase activity	Molecular function	25255805
KCNJ1	3758	potassium channel, inwardly rectifying subfamily J, member 1	tissue homeostasis	Biological process	-
MAP1S	55201	microtubule-associated protein 1S	beta-tubulin binding	Molecular function	12762840
CCL21	6366	chemokine (C-C motif) ligand 21	mesangial cell-matrix adhesion	Biological process	15569314
RCVRN	5957	recoverin	regulation of calcium ion transport	Biological process	-
ATG12	9140	autophagy related 12	innate immune response	Biological process	-
GNAT1	2779	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1	detection of chemical stimulus involved in sensory perception of bitter taste	Biological process	-
WWC2	80014	WW and C2 domain containing 2	kinase binding	Molecular function	24682284
CBX2	84733	chromobox homolog 2	cellular protein metabolic process	Biological process	-
RPS15	6209	ribosomal protein S15	viral process	Biological process	-
ZNF461	92283	zinc finger protein 461	transcription, DNA-templated	Biological process	-
PPP5C	5536	protein phosphatase 5, catalytic subunit	response to morphine	Biological process	-
GSK3A	2931	glycogen synthase kinase 3 alpha	cellular response to interleukin-3	Biological process	-
SERPINB3	6317	serpin peptidase inhibitor, clade B (ovalbumin), member 3	negative regulation of catalytic activity	Biological process	10956412
DPM1	8813	dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit	cellular protein metabolic process	Biological process	-
PLCL1	5334	phospholipase C-like 1	GABA receptor binding	Molecular function	-
SDHA	6389	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	mitochondrial inner membrane	Cellular component	-
ZXDC	79364	ZXD family zinc finger C	C2H2 zinc finger domain binding	Molecular function	17493635
PIK3CD	5293	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	cytoplasm	Cellular component	-
ATXN3L	92552	ataxin 3-like	nuclear inclusion body	Cellular component	-
HNF4A	3172	hepatocyte nuclear factor 4, alpha	glucose homeostasis	Biological process	-
GATA4	2626	GATA binding protein 4	response to retinoic acid	Biological process	-
AURKAIP1	54998	aurora kinase A interacting protein 1	positive regulation of proteolysis	Biological process	12244051
SPHK2	56848	sphingosine kinase 2	ATP binding	Molecular function	-
CYP1A2	1544	cytochrome P450, family 1, subfamily A, polypeptide 2	dibenzo-p-dioxin metabolic process	Biological process	-
STAT5B	6777	signal transducer and activator of transcription 5B	nucleoplasm	Cellular component	-
PACSIN3	29763	protein kinase C and casein kinase substrate in neurons 3	regulation of endocytosis	Biological process	-
GREM1	26585	gremlin 1, DAN family BMP antagonist	apoptotic process	Biological process	-
SLC25A6	293	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6	apoptotic process	Biological process	-
EIF1B	10289	eukaryotic translation initiation factor 1B	cellular_component	Cellular component	-
VHL	7428	von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase	regulation of transcription from RNA polymerase II promoter in response to hypoxia	Biological process	-
CDH11	1009	cadherin 11, type 2, OB-cadherin (osteoblast)	adherens junction organization	Biological process	-
HES5	388585	hes family bHLH transcription factor 5	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	-
CKLF	51192	chemokine-like factor	integral component of membrane	Cellular component	11415443
PDCL	5082	phosducin-like	cytoplasm	Cellular component	-
LEF1	51176	lymphoid enhancer-binding factor 1	sequence-specific DNA binding transcription factor activity	Molecular function	11751639
NBEAL2	23218	neurobeachin-like 2	extrinsic component of membrane	Cellular component	-
MYOF	26509	myoferlin	caveola	Cellular component	-
KLK1	3816	kallikrein 1	serine-type endopeptidase activity	Molecular function	7749372
EVI5	7813	ecotropic viral integration site 5	regulation of cilium assembly	Biological process	17646400
DTNBP1	84062	dystrobrevin binding protein 1	postsynaptic membrane	Cellular component	-
ESX1	80712	ESX homeobox 1	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	15897875
CARD17	440068	caspase recruitment domain family, member 17	negative regulation of endopeptidase activity	Biological process	-
XRN1	54464	5'-3' exoribonuclease 1	nucleic acid phosphodiester bond hydrolysis	Biological process	-
BATF2	116071	basic leucine zipper transcription factor, ATF-like 2	protein binding	Molecular function	16189514
BTRC	8945	beta-transducin repeat containing E3 ubiquitin protein ligase	ubiquitin-dependent protein catabolic process	Biological process	15448698
PHF8	23133	PHD finger protein 8	histone demethylase activity (H4-K20 specific)	Molecular function	20622853
GRM5	2915	glutamate receptor, metabotropic 5	desensitization of G-protein coupled receptor protein signaling pathway	Biological process	-
KRTAP12-2	353323	keratin associated protein 12-2	protein binding	Molecular function	25416956
NKX2-1	7080	NK2 homeobox 1	globus pallidus development	Biological process	11854319
MDM2	4193	MDM2 proto-oncogene, E3 ubiquitin protein ligase	protein complex assembly	Biological process	10608892
FER	2241	fer (fps/fes related) tyrosine kinase	regulation of lamellipodium assembly	Biological process	19738202
ASB2	51676	ankyrin repeat and SOCS box containing 2	protein polyubiquitination	Biological process	-
LAGE3	8270	L antigen family, member 3	protein binding	Molecular function	25416956
KAT7	11143	K(lysine) acetyltransferase 7	zinc ion binding	Molecular function	-
SOD1	6647	superoxide dismutase 1, soluble	positive regulation of apoptotic process	Biological process	16790527
CCDC180	100499483	coiled-coil domain containing 180	integral component of membrane	Cellular component	-
UGT2B4	7363	UDP glucuronosyltransferase 2 family, polypeptide B4	glucuronosyltransferase activity	Molecular function	18052087
TFAP2A	7020	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	sequence-specific DNA binding	Molecular function	12586840
HIST1H2BC	8347	histone cluster 1, H2bc	nucleosome	Cellular component	422550
ALKBH5	54890	AlkB family member 5, RNA demethylase	oxidative single-stranded RNA demethylation	Biological process	23177736
ATP2B2	491	ATPase, Ca++ transporting, plasma membrane 2	protein C-terminus binding	Molecular function	11786550
TADA1	117143	transcriptional adaptor 1	nucleoplasm	Cellular component	-
ATP2B4	493	ATPase, Ca++ transporting, plasma membrane 4	integral component of plasma membrane	Cellular component	2137451
COG5	10466	component of oligomeric golgi complex 5	nucleoplasm	Cellular component	-
ERV3-1	2086	endogenous retrovirus group 3, member 1	molecular_function	Molecular function	-
NPS	594857	neuropeptide S	positive regulation of action potential	Biological process	-
PXDN	7837	peroxidasin	peroxidase activity	Molecular function	18929642
SELE	6401	selectin E	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	Biological process	18029551
HYAL1	3373	hyaluronoglucosaminidase 1	positive regulation of epithelial cell migration	Biological process	21829529
CAMK1D	57118	calcium/calmodulin-dependent protein kinase ID	regulation of granulocyte chemotaxis	Biological process	15840691
FBXO7	25793	F-box protein 7	negative regulation of lymphocyte differentiation	Biological process	-
SLC39A1	27173	solute carrier family 39 (zinc transporter), member 1	integral component of membrane	Cellular component	-
BTK	695	Bruton agammaglobulinemia tyrosine kinase	peptidyl-tyrosine autophosphorylation	Biological process	-
DCDC2B	149069	doublecortin domain containing 2B	intracellular signal transduction	Biological process	-
PCK2	5106	phosphoenolpyruvate carboxykinase 2 (mitochondrial)	oxaloacetate metabolic process	Biological process	-
TCAF1	9747	TRPM8 channel-associated factor 1	protein binding	Molecular function	16189514
MAPK7	5598	mitogen-activated protein kinase 7	signal transduction	Biological process	7646528
IRS2	8660	insulin receptor substrate 2	positive regulation of glucose import	Biological process	16814735
LEF1	51176	lymphoid enhancer-binding factor 1	positive regulation of epithelial to mesenchymal transition	Biological process	20018240
FSHR	2492	follicle stimulating hormone receptor	gonad development	Biological process	9020851
PRKCA	5578	protein kinase C, alpha	cellular calcium ion homeostasis	Biological process	-
GUF1	60558	GUF1 GTPase homolog (S. cerevisiae)	translation	Biological process	-
OR1D4	653166	olfactory receptor, family 1, subfamily D, member 4 (gene/pseudogene)	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
TULP2	7288	tubby like protein 2	cytoplasm	Cellular component	-
PDE4D	5144	phosphodiesterase 4D, cAMP-specific	positive regulation of interleukin-2 production	Biological process	17404263
TBCA	6902	tubulin folding cofactor A	microtubule cytoskeleton	Cellular component	-
MAGED1	9500	melanoma antigen family D1	positive regulation of apoptotic process	Biological process	-
VAMP3	9341	vesicle-associated membrane protein 3	Golgi to plasma membrane protein transport	Biological process	-
SRI	6717	sorcin	intracellular sequestering of iron ion	Biological process	9668070
CNTNAP1	8506	contactin associated protein 1	neuromuscular process controlling balance	Biological process	-
TOX2	84969	TOX high mobility group box family member 2	female gonad development	Biological process	-
LMNA	4000	lamin A/C	lamin filament	Cellular component	10080180
GGT7	2686	gamma-glutamyltransferase 7	protein binding	Molecular function	25416956
IL33	90865	interleukin 33	cytokine activity	Molecular function	19841166
TRIM15	89870	tripartite motif containing 15	positive regulation of NF-kappaB transcription factor activity	Biological process	23077300
SLC11A1	6556	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1	cadmium ion transmembrane transport	Biological process	17932044
TSPY8	728403	testis specific protein, Y-linked 8	cytoplasm	Cellular component	-
PARD6A	50855	par-6 family cell polarity regulator alpha	Rho GTPase binding	Molecular function	-
SIRPB1	10326	signal-regulatory protein beta 1	integral component of membrane	Cellular component	-
GPR68	8111	G protein-coupled receptor 68	G-protein coupled receptor activity	Molecular function	-
ANKH	56172	ANKH inorganic pyrophosphate transport regulator	transmembrane transport	Biological process	-
TSC22D3	1831	TSC22 domain family, member 3	sequence-specific DNA binding transcription factor activity	Molecular function	-
FAM76B	143684	family with sequence similarity 76, member B	NEDD8-specific protease activity	Molecular function	-
ARV1	64801	ARV1 homolog (S. cerevisiae)	cholesterol transport	Biological process	-
NCKAP1	10787	NCK-associated protein 1	apoptotic process	Biological process	10673335
CILP2	148113	cartilage intermediate layer protein 2	proteinaceous extracellular matrix	Cellular component	-
SH2B1	25970	SH2B adaptor protein 1	protein binding	Molecular function	16273093
VPS29	51699	vacuolar protein sorting 29 homolog (S. cerevisiae)	protein transporter activity	Molecular function	-
KCNQ2	3785	potassium channel, voltage gated KQT-like subfamily Q, member 2	axon initial segment	Cellular component	16525039
ITGB3	3690	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	extracellular matrix binding	Molecular function	22505472
MTM1	4534	myotubularin 1	phospholipid metabolic process	Biological process	-
TFRC	7037	transferrin receptor	glycoprotein binding	Molecular function	9465039
TMOD2	29767	tropomodulin 2 (neuronal)	positive regulation of G-protein coupled receptor protein signaling pathway	Biological process	-
PDGFA	5154	platelet-derived growth factor alpha polypeptide	positive regulation of protein kinase B signaling	Biological process	19019919
ACSL3	2181	acyl-CoA synthetase long-chain family member 3	membrane	Cellular component	19946888
CDKN2A	1029	cyclin-dependent kinase inhibitor 2A	transcription factor binding	Molecular function	19057511
ASPH	444	aspartate beta-hydroxylase	negative regulation of cell proliferation	Biological process	-
PITX1	5307	paired-like homeodomain 1	transcription, DNA-templated	Biological process	-
EDN1	1906	endothelin 1	protein binding	Molecular function	23597562
DCP2	167227	decapping mRNA 2	intracellular membrane-bounded organelle	Cellular component	-
ZFPM2	23414	zinc finger protein, FOG family member 2	negative regulation of transcription, DNA-templated	Biological process	20206639
RASEF	158158	RAS and EF-hand domain containing	GTP binding	Molecular function	-
SIRT6	51548	sirtuin 6	NAD-dependent histone deacetylase activity (H3-K9 specific)	Molecular function	18337721
JUNB	3726	jun B proto-oncogene	chromatin	Cellular component	2513129
FANCC	2176	Fanconi anemia, complementation group C	removal of superoxide radicals	Biological process	-
SLCO1C1	53919	solute carrier organic anion transporter family, member 1C1	sodium-independent organic anion transport	Biological process	-
FGF13	2258	fibroblast growth factor 13	axon	Cellular component	-
SIRT1	23411	sirtuin 1	negative regulation of helicase activity	Biological process	18203716
NME2	4831	NME/NM23 nucleoside diphosphate kinase 2	cytoplasm	Cellular component	15703214
AOC1	26	amine oxidase, copper containing 1	propane-1,3-diamine oxidase activity	Molecular function	-
PIK3C2B	5287	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta	1-phosphatidylinositol-3-kinase activity	Molecular function	-
TLR5	7100	toll-like receptor 5	cellular response to mechanical stimulus	Biological process	19593445
NEK1	4750	NIMA-related kinase 1	cellular response to DNA damage stimulus	Biological process	-
ZNF83	55769	zinc finger protein 83	transcription, DNA-templated	Biological process	-
OR8H2	390151	olfactory receptor, family 8, subfamily H, member 2	integral component of plasma membrane	Cellular component	-
PCID2	55795	PCI domain containing 2	positive regulation of transcription, DNA-templated	Biological process	20870947
PAF1	54623	Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)	endodermal cell fate commitment	Biological process	-
NAT1	9	N-acetyltransferase 1 (arylamine N-acetyltransferase)	small molecule metabolic process	Biological process	-
SUV39H1	6839	suppressor of variegation 3-9 homolog 1 (Drosophila)	cell differentiation	Biological process	-
TFR2	7036	transferrin receptor 2	glycoprotein binding	Molecular function	22728873
B3GNT5	84002	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5	glycolipid biosynthetic process	Biological process	11384981
SEH1L	81929	SEH1-like (S. cerevisiae)	mRNA transport	Biological process	-
PSMB6	5694	proteasome (prosome, macropain) subunit, beta type, 6	viral process	Biological process	-
INO80E	283899	INO80 complex subunit E	DNA replication	Biological process	-
BMPR2	659	bone morphogenetic protein receptor, type II (serine/threonine kinase)	regulation of lung blood pressure	Biological process	-
IKZF2	22807	IKAROS family zinc finger 2 (Helios)	metal ion binding	Molecular function	-
MARCO	8685	macrophage receptor with collagenous structure	integral component of plasma membrane	Cellular component	9468508
IFNA1	3439	interferon, alpha 1	type I interferon signaling pathway	Biological process	-
NR4A3	8013	nuclear receptor subfamily 4, group A, member 3	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
PCDHB4	56131	protocadherin beta 4	integral component of plasma membrane	Cellular component	10380929
CA2	760	carbonic anhydrase II	secretion	Biological process	-
RANGAP1	5905	Ran GTPase activating protein 1	perinuclear region of cytoplasm	Cellular component	-
ITGB1	3688	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	maternal process involved in female pregnancy	Biological process	-
UNCX	340260	UNC homeobox	nucleus	Cellular component	-
IGF2R	3482	insulin-like growth factor 2 receptor	extracellular exosome	Cellular component	19056867
STEAP3	55240	STEAP family member 3, metalloreductase	ferric iron import into cell	Biological process	-
TADA3	10474	transcriptional adaptor 3	intracellular	Cellular component	-
NOL9	79707	nucleolar protein 9	RNA binding	Molecular function	-
ADAM9	8754	ADAM metallopeptidase domain 9	response to laminar fluid shear stress	Biological process	-
PLD5	200150	phospholipase D family, member 5	metabolic process	Biological process	-
SMO	6608	smoothened, frizzled class receptor	multicellular organism growth	Biological process	-
CNOT7	29883	CCR4-NOT transcription complex, subunit 7	RNA phosphodiester bond hydrolysis, exonucleolytic	Biological process	-
RHOU	58480	ras homolog family member U	cytoskeleton organization	Biological process	21834987
LSM11	134353	LSM11, U7 small nuclear RNA associated	gene expression	Biological process	-
KCNF1	3754	potassium channel, voltage gated modifier subfamily F, member 1	potassium ion transmembrane transport	Biological process	-
FOSB	2354	FBJ murine osteosarcoma viral oncogene homolog B	response to progesterone	Biological process	-
GH1	2688	growth hormone 1	positive regulation of phosphatidylinositol 3-kinase signaling	Biological process	7782332
RFTN1	23180	raftlin, lipid raft linker 1	interleukin-17 production	Biological process	-
ZFHX3	463	zinc finger homeobox 3	regulation of neuron differentiation	Biological process	-
AK1	203	adenylate kinase 1	nucleoside triphosphate biosynthetic process	Biological process	23416111
ASPG	374569	asparaginase	lipid catabolic process	Biological process	-
APBB2	323	amyloid beta (A4) precursor protein-binding, family B, member 2	nucleus	Cellular component	-
ALDOA	226	aldolase A, fructose-bisphosphate	carbohydrate metabolic process	Biological process	-
PPP1CB	5500	protein phosphatase 1, catalytic subunit, beta isozyme	triglyceride catabolic process	Biological process	-
CDC42	998	cell division cycle 42	extracellular exosome	Cellular component	19056867
CAST	831	calpastatin	endopeptidase inhibitor activity	Molecular function	7638179
VN1R1	57191	vomeronasal 1 receptor 1	integral component of membrane	Cellular component	-
TGFB1	7040	transforming growth factor, beta 1	extrinsic apoptotic signaling pathway	Biological process	15334054
TSPO	706	translocator protein (18kDa)	positive regulation of mitochondrial depolarization	Biological process	-
CLIC4	25932	chloride intracellular channel 4	fertilization	Biological process	-
GCC2	9648	GRIP and coiled-coil domain containing 2	protein targeting to Golgi	Biological process	-
IPMK	253430	inositol polyphosphate multikinase	inositol tetrakisphosphate 3-kinase activity	Molecular function	-
LUM	4060	lumican	collagen fibril organization	Biological process	10892350
MRPL36	64979	mitochondrial ribosomal protein L36	mitochondrial translational elongation	Biological process	-
RPS9	6203	ribosomal protein S9	translational termination	Biological process	-
NR2F2	7026	nuclear receptor subfamily 2, group F, member 2	steroid hormone mediated signaling pathway	Biological process	-
RNF4	6047	ring finger protein 4	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological process	18408734
LYN	4067	LYN proto-oncogene, Src family tyrosine kinase	dendritic cell differentiation	Biological process	-
SOST	50964	sclerostin	ossification	Biological process	-
RALGAPB	57148	Ral GTPase activating protein, beta subunit (non-catalytic)	Ral protein signal transduction	Biological process	-
IKBKB	3551	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	serine phosphorylation of STAT protein	Biological process	21399639
FIGLA	344018	folliculogenesis specific basic helix-loop-helix	transcription, DNA-templated	Biological process	-
TMEM88	92162	transmembrane protein 88	integral component of membrane	Cellular component	-
WISP1	8840	WNT1 inducible signaling pathway protein 1	negative regulation of cell death	Biological process	-
AK9	221264	adenylate kinase 9	dGDP phosphorylation	Biological process	23416111
ADAM17	6868	ADAM metallopeptidase domain 17	negative regulation of transforming growth factor beta receptor signaling pathway	Biological process	21170088
UBE2J1	51465	ubiquitin-conjugating enzyme E2, J1	ATP binding	Molecular function	-
EDN3	1908	endothelin 3	positive regulation of leukocyte chemotaxis	Biological process	9696419
MANBA	4126	mannosidase, beta A, lysosomal	beta-mannosidase activity	Molecular function	-
ZIC3	7547	Zic family member 3	nucleus	Cellular component	-
RASSF6	166824	Ras association (RalGDS/AF-6) domain family member 6	protein binding	Molecular function	20920251
ZNF385A	25946	zinc finger protein 385A	nucleolus	Cellular component	-
MYH10	4628	myosin, heavy chain 10, non-muscle	exocytosis	Biological process	-
AOX1	316	aldehyde oxidase 1	flavin adenine dinucleotide binding	Molecular function	-
EEF1D	1936	eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)	activating transcription factor binding	Molecular function	21597468
CLC	1178	Charcot-Leyden crystal galectin	regulation of T cell anergy	Biological process	17502455
RALBP1	10928	ralA binding protein 1	Ral GTPase binding	Molecular function	24056301
ARFGAP2	84364	ADP-ribosylation factor GTPase activating protein 2	Golgi membrane	Cellular component	-
PTEN	5728	phosphatase and tensin homolog	negative regulation of cell aging	Biological process	-
OR5L1	219437	olfactory receptor, family 5, subfamily L, member 1 (gene/pseudogene)	odorant binding	Molecular function	-
EPCAM	4072	epithelial cell adhesion molecule	bicellular tight junction	Cellular component	16054130
BMP2	650	bone morphogenetic protein 2	BMP receptor binding	Molecular function	7811286
RAB4A	5867	RAB4A, member RAS oncogene family	regulation of endocytosis	Biological process	-
ZFAND6	54469	zinc finger, AN1-type domain 6	cellular_component	Cellular component	-
PAF1	54623	Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)	protein localization to nucleus	Biological process	22046413
E4F1	1877	E4F transcription factor 1	viral process	Biological process	-
POMZP3	22932	POM121 and ZP3 fusion	biological_process	Biological process	-
MOCS2	4338	molybdenum cofactor synthesis 2	extracellular exosome	Cellular component	23376485
MAP7D1	55700	MAP7 domain containing 1	spindle	Cellular component	-
CHMP5	51510	charged multivesicular body protein 5	cytosol	Cellular component	-
PCSK5	5125	proprotein convertase subtilisin/kexin type 5	serine-type endopeptidase activity	Molecular function	8901832
PDZD11	51248	PDZ domain containing 11	ion transmembrane transport	Biological process	-
NBN	4683	nibrin	nuclear inclusion body	Cellular component	12447371
RITA1	84934	RBPJ interacting and tubulin associated 1	Notch signaling pathway	Biological process	-
BTK	695	Bruton agammaglobulinemia tyrosine kinase	mesoderm development	Biological process	8013627
CPSF7	79869	cleavage and polyadenylation specific factor 7, 59kDa	mRNA splicing, via spliceosome	Biological process	-
DRD3	1814	dopamine receptor D3	negative regulation of sodium:proton antiporter activity	Biological process	-
TNKS2	80351	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2	regulation of multicellular organism growth	Biological process	-
GJD3	125111	gap junction protein, delta 3, 31.9kDa	protein binding	Molecular function	12154091
CCT5	22948	chaperonin containing TCP1, subunit 5 (epsilon)	extracellular exosome	Cellular component	19056867
POM121L4P	266697	POM121 transmembrane nucleoporin-like 4 pseudogene	cellular_component	Cellular component	-
LRRK2	120892	leucine-rich repeat kinase 2	identical protein binding	Molecular function	16321986
FGD1	2245	FYVE, RhoGEF and PH domain containing 1	cytosol	Cellular component	-
SGCD	6444	sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)	cytoskeleton	Cellular component	-
RPGRIP1L	23322	RPGRIP1-like	corpus callosum development	Biological process	-
ZNF555	148254	zinc finger protein 555	metal ion binding	Molecular function	-
COL8A2	1296	collagen, type VIII, alpha 2	basement membrane	Cellular component	2019595
APOE	348	apolipoprotein E	cholesterol efflux	Biological process	11162594
CCL5	6352	chemokine (C-C motif) ligand 5	positive regulation of smooth muscle cell proliferation	Biological process	21297082
ETS1	2113	v-ets avian erythroblastosis virus E26 oncogene homolog 1	histone acetyltransferase binding	Molecular function	-
EIF4EBP1	1978	eukaryotic translation initiation factor 4E binding protein 1	G1/S transition of mitotic cell cycle	Biological process	14673156
LYST	1130	lysosomal trafficking regulator	cytosol	Cellular component	-
PAK7	57144	p21 protein (Cdc42/Rac)-activated kinase 7	regulation of mitotic cell cycle	Biological process	-
PCDHGA3	56112	protocadherin gamma subfamily A, 3	plasma membrane	Cellular component	-
AES	166	amino-terminal enhancer of split	positive regulation of anoikis	Biological process	15006356
DVL1	1855	dishevelled segment polarity protein 1	protein localization to nucleus	Biological process	10330181
ADAM17	6868	ADAM metallopeptidase domain 17	spleen development	Biological process	10433800
UCP2	7351	uncoupling protein 2 (mitochondrial, proton carrier)	cellular metabolic process	Biological process	-
C14orf166	51637	chromosome 14 open reading frame 166	nucleoplasm	Cellular component	-
DCLRE1C	64421	DNA cross-link repair 1C	telomere maintenance	Biological process	-
STRBP	55342	spermatid perinuclear RNA binding protein	spermatid development	Biological process	-
SLC6A5	9152	solute carrier family 6 (neurotransmitter transporter), member 5	plasma membrane	Cellular component	-
IL2	3558	interleukin 2	extracellular space	Cellular component	6608729
ARAP3	64411	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	lamellipodium	Cellular component	-
TMEM242	729515	transmembrane protein 242	integral component of membrane	Cellular component	-
ZBTB41	360023	zinc finger and BTB domain containing 41	DNA binding	Molecular function	-
RFC1	5981	replication factor C (activator 1) 1, 145kDa	transcription, DNA-templated	Biological process	-
MAP3K8	1326	mitogen-activated protein kinase kinase kinase 8	cytosol	Cellular component	-
AOC3	8639	amine oxidase, copper containing 3	cytoplasm	Cellular component	23349812
FRMD5	84978	FERM domain containing 5	molecular_function	Molecular function	-
SMARCE1	6605	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	chromatin binding	Molecular function	9435219
HIST1H1T	3010	histone cluster 1, H1t	nucleus	Cellular component	21630459
MTNR1A	4543	melatonin receptor 1A	positive regulation of cGMP biosynthetic process	Biological process	10531408
CDX4	1046	caudal type homeobox 4	positive regulation of transcription from RNA polymerase II promoter	Biological process	21471217
LRP3	4037	low density lipoprotein receptor-related protein 3	integral component of membrane	Cellular component	-
SLC11A2	4891	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2	cell surface	Cellular component	-
SNRPB	6628	small nuclear ribonucleoprotein polypeptides B and B1	mRNA 3'-end processing	Biological process	-
AMOT	154796	angiomotin	angiostatin binding	Molecular function	11257124
CX3CL1	6376	chemokine (C-X3-C motif) ligand 1	angiogenesis involved in wound healing	Biological process	-
CEP350	9857	centrosomal protein 350kDa	protein binding	Molecular function	25134987
TLN1	7094	talin 1	structural constituent of cytoskeleton	Molecular function	10610730
OR2J2	26707	olfactory receptor, family 2, subfamily J, member 2	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
MS4A15	219995	membrane-spanning 4-domains, subfamily A, member 15	integral component of membrane	Cellular component	-
SDF4	51150	stromal cell derived factor 4	protein binding	Molecular function	17442889
ADAMTS4	9507	ADAM metallopeptidase with thrombospondin type 1 motif, 4	skeletal system development	Biological process	10356395
TG	7038	thyroglobulin	thyroid hormone metabolic process	Biological process	-
POLA1	5422	polymerase (DNA directed), alpha 1, catalytic subunit	mitotic cell cycle	Biological process	-
PSMC5	5705	proteasome (prosome, macropain) 26S subunit, ATPase, 5	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological process	12110588
IL7R	3575	interleukin 7 receptor	B cell proliferation	Biological process	-
SFRP1	6422	secreted frizzled-related protein 1	negative regulation of fibroblast apoptotic process	Biological process	14581477
PSMD9	5715	proteasome (prosome, macropain) 26S subunit, non-ATPase, 9	cytoplasm	Cellular component	-
PAXBP1	94104	PAX3 and PAX7 binding protein 1	transcription factor binding	Molecular function	-
IRF3	3661	interferon regulatory factor 3	cytoplasm	Cellular component	-
ZNF189	7743	zinc finger protein 189	activation of mitophagy in response to mitochondrial depolarization	Biological process	22020285
YWHAQ	10971	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta	cytoplasmic vesicle membrane	Cellular component	-
SH2D2A	9047	SH2 domain containing 2A	protein binding	Molecular function	10553045
STX4	6810	syntaxin 4	post-Golgi vesicle-mediated transport	Biological process	-
PRKCA	5578	protein kinase C, alpha	activation of phospholipase C activity	Biological process	-
RAB3A	5864	RAB3A, member RAS oncogene family	endosome	Cellular component	-
CYP26C1	340665	cytochrome P450, family 26, subfamily C, polypeptide 1	oxidation-reduction process	Biological process	14532297
TMOD1	7111	tropomodulin 1	striated muscle thin filament	Cellular component	-
APOA5	116519	apolipoprotein A-V	extracellular space	Cellular component	18635818
LYG1	129530	lysozyme G-like 1	cell wall macromolecule catabolic process	Biological process	-
TBC1D9B	23061	TBC1 domain family, member 9B (with GRAM domain)	calcium ion binding	Molecular function	-
UCHL5	51377	ubiquitin carboxyl-terminal hydrolase L5	regulation of proteasomal protein catabolic process	Biological process	18162577
TUB	7275	tubby bipartite transcription factor	receptor localization to nonmotile primary cilium	Biological process	-
DLG1	1739	discs, large homolog 1 (Drosophila)	cell junction	Cellular component	12857860
C10orf54	64115	chromosome 10 open reading frame 54	BMP signaling pathway	Biological process	-
AFG3L2	10939	AFG3-like AAA ATPase 2	neuromuscular junction development	Biological process	-
LHX4	89884	LIM homeobox 4	protein binding	Molecular function	25416956
LDLR	3949	low density lipoprotein receptor	cholesterol metabolic process	Biological process	-
GEM	2669	GTP binding protein overexpressed in skeletal muscle	nucleus	Cellular component	-
RDH12	145226	retinol dehydrogenase 12 (all-trans/9-cis/11-cis)	photoreceptor inner segment membrane	Cellular component	-
GCM2	9247	glial cells missing homolog 2 (Drosophila)	sequence-specific DNA binding	Molecular function	15863676
CANT1	124583	calcium activated nucleotidase 1	extracellular exosome	Cellular component	23376485
ADAMTSL4	54507	ADAMTS-like 4	protein O-linked fucosylation	Biological process	-
SLC8A1	6546	solute carrier family 8 (sodium/calcium exchanger), member 1	ion channel binding	Molecular function	-
MEN1	4221	multiple endocrine neoplasia I	double-stranded DNA binding	Molecular function	15331604
PSEN1	5663	presenilin 1	negative regulation of apoptotic signaling pathway	Biological process	-
NOTCH2	4853	notch 2	positive regulation of apoptotic process	Biological process	-
NFASC	23114	neurofascin	node of Ranvier	Cellular component	16652168
SNF8	11267	SNF8, ESCRT-II complex subunit	recycling endosome	Cellular component	17714434
COL4A3	1285	collagen, type IV, alpha 3 (Goodpasture antigen)	axon guidance	Biological process	-
KLK6	5653	kallikrein-related peptidase 6	endoplasmic reticulum	Cellular component	-
PCNT	5116	pericentrin	calmodulin binding	Molecular function	-
IL18	3606	interleukin 18	interleukin-13 biosynthetic process	Biological process	10227975
ADAM17	6868	ADAM metallopeptidase domain 17	positive regulation of cellular component movement	Biological process	10433800
LARS	51520	leucyl-tRNA synthetase	gene expression	Biological process	-
SAT1	6303	spermidine/spermine N1-acetyltransferase 1	spermidine binding	Molecular function	-
DDR2	4921	discoidin domain receptor tyrosine kinase 2	collagen-activated tyrosine kinase receptor signaling pathway	Biological process	16186108
MYB	4602	v-myb avian myeloblastosis viral oncogene homolog	negative regulation of transcription from RNA polymerase II promoter	Biological process	20531406
CD320	51293	CD320 molecule	small molecule metabolic process	Biological process	-
PPP2CA	5515	protein phosphatase 2, catalytic subunit, alpha isozyme	metal ion binding	Molecular function	-
VAMP2	6844	vesicle-associated membrane protein 2 (synaptobrevin 2)	clathrin-sculpted monoamine transport vesicle membrane	Cellular component	-
P4HA3	283208	prolyl 4-hydroxylase, alpha polypeptide III	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	Molecular function	-
PROCR	10544	protein C receptor, endothelial	leukocyte migration	Biological process	-
SLC4A4	8671	solute carrier family 4 (sodium bicarbonate cotransporter), member 4	bicarbonate transport	Biological process	-
NRL	4901	neural retina leucine zipper	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	8552602
PRPSAP2	5636	phosphoribosyl pyrophosphate synthetase-associated protein 2	ribose phosphate diphosphokinase activity	Molecular function	-
ATP6AP1	537	ATPase, H+ transporting, lysosomal accessory protein 1	Rab GTPase binding	Molecular function	-
TYMS	7298	thymidylate synthetase	cytoplasm	Cellular component	21876188
RBL1	5933	retinoblastoma-like 1	transcription factor complex	Cellular component	-
GNA11	2767	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)	GTP binding	Molecular function	-
EGFL6	25975	EGF-like-domain, multiple 6	cell differentiation	Biological process	-
RSPO1	284654	R-spondin 1	receptor binding	Molecular function	22615920
USP22	23326	ubiquitin specific peptidase 22	zinc ion binding	Molecular function	-
DUSP26	78986	dual specificity phosphatase 26 (putative)	positive regulation of peptidyl-serine dephosphorylation	Biological process	20562916
PPP2R3A	5523	protein phosphatase 2, regulatory subunit B'', alpha	protein binding	Molecular function	15687260
MTMR8	55613	myotubularin related protein 8	nuclear envelope	Cellular component	-
INPP5B	3633	inositol polyphosphate-5-phosphatase, 75kDa	metal ion binding	Molecular function	-
DHX15	1665	DEAH (Asp-Glu-Ala-His) box helicase 15	poly(A) RNA binding	Molecular function	22658674
APEH	327	acylaminoacyl-peptide hydrolase	protein binding	Molecular function	16189514
ETS2	2114	v-ets avian erythroblastosis virus E26 oncogene homolog 2	skeletal system development	Biological process	8596630
PRDM14	63978	PR domain containing 14	cell morphogenesis	Biological process	-
CDKN2D	1032	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	response to UV	Biological process	15750620
UNC5D	137970	unc-5 homolog D (C. elegans)	integral component of membrane	Cellular component	-
TJP1	7082	tight junction protein 1	hippo signaling	Biological process	-
GLOD4	51031	glyoxalase domain containing 4	mitochondrion	Cellular component	-
INF2	64423	inverted formin, FH2 and WH2 domain containing	regulation of cellular component size	Biological process	-
SMPD4	55627	sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)	sphingomyelin phosphodiesterase activity	Molecular function	-
CXCL10	3627	chemokine (C-X-C motif) ligand 10	extracellular region	Cellular component	-
HAUS5	23354	HAUS augmin-like complex, subunit 5	HAUS complex	Cellular component	19369198
ICE1	23379	interactor of little elongation complex ELL subunit 1	Cajal body	Cellular component	22195968
LAP3	51056	leucine aminopeptidase 3	metalloexopeptidase activity	Molecular function	1908238
IL12A	3592	interleukin 12A	positive regulation of cell adhesion	Biological process	7903063
SMAD1	4086	SMAD family member 1	signal transduction	Biological process	9759503
KAT7	11143	K(lysine) acetyltransferase 7	histone acetyltransferase complex	Cellular component	16387653
HBA2	3040	hemoglobin, alpha 2	hemoglobin complex	Cellular component	7555018
DHRS7C	201140	dehydrogenase/reductase (SDR family) member 7C	sarcoplasmic reticulum membrane	Cellular component	-
CA7	766	carbonic anhydrase VII	zinc ion binding	Molecular function	-
CITED2	10370	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	embryonic heart tube left/right pattern formation	Biological process	-
INHA	3623	inhibin, alpha	photoreceptor inner segment	Cellular component	-
PAK1	5058	p21 protein (Cdc42/Rac)-activated kinase 1	Golgi apparatus	Cellular component	-
PDE3A	5139	phosphodiesterase 3A, cGMP-inhibited	metal ion binding	Molecular function	-
NPM3	10360	nucleophosmin/nucleoplasmin 3	rRNA processing	Biological process	-
SMC3	9126	structural maintenance of chromosomes 3	basement membrane	Cellular component	9015313
CSGALNACT2	55454	chondroitin sulfate N-acetylgalactosaminyltransferase 2	integral component of Golgi membrane	Cellular component	11788602
GZMH	2999	granzyme H (cathepsin G-like 2, protein h-CCPX)	immune response	Biological process	-
SOX11	6664	SRY (sex determining region Y)-box 11	somite development	Biological process	-
UTS2R	2837	urotensin 2 receptor	plasma membrane	Cellular component	-
RPA2	6118	replication protein A2, 32kDa	G1/S transition of mitotic cell cycle	Biological process	-
VEGFC	7424	vascular endothelial growth factor C	induction of positive chemotaxis	Biological process	19275959
RFX8	731220	RFX family member 8, lacking RFX DNA binding domain	endocrine pancreas development	Biological process	-
ESRRA	2101	estrogen-related receptor alpha	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
TWSG1	57045	twisted gastrulation BMP signaling modulator 1	negative regulation of osteoblast differentiation	Biological process	-
VAV3	10451	vav 3 guanine nucleotide exchange factor	regulation of small GTPase mediated signal transduction	Biological process	-
IFNB1	3456	interferon, beta 1, fibroblast	B cell activation involved in immune response	Biological process	12932356
NUP133	55746	nucleoporin 133kDa	mRNA export from nucleus	Biological process	11684705
CLDN11	5010	claudin 11	axon ensheathment	Biological process	-
NDUFS3	4722	NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)	small molecule metabolic process	Biological process	-
PKM	5315	pyruvate kinase, muscle	small molecule metabolic process	Biological process	-
JUP	3728	junction plakoglobin	protein phosphatase binding	Molecular function	8663237
RRAS	6237	related RAS viral (r-ras) oncogene homolog	axon guidance	Biological process	-
MMS19	64210	MMS19 nucleotide excision repair homolog (S. cerevisiae)	phosphorelay signal transduction system	Biological process	11279242
CHMP1B	57132	charged multivesicular body protein 1B	ESCRT III complex	Cellular component	24878737
VSX1	30813	visual system homeobox 1	cellular_component	Cellular component	-
SIX3	6496	SIX homeobox 3	forebrain anterior/posterior pattern specification	Biological process	-
SMAD4	4089	SMAD family member 4	sequence-specific DNA binding transcription factor activity	Molecular function	10823886
KCNA4	3739	potassium channel, voltage gated shaker related subfamily A, member 4	potassium ion binding	Molecular function	-
POLR3GL	84265	polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like	transcription elongation from RNA polymerase III promoter	Biological process	-
MAP2K5	5607	mitogen-activated protein kinase kinase 5	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
CAMTA2	23125	calmodulin binding transcription activator 2	nucleus	Cellular component	16678093
STRN	6801	striatin, calmodulin binding protein	dendritic spine	Cellular component	-
TRAF2	7186	TNF receptor-associated factor 2	negative regulation of glial cell apoptotic process	Biological process	-
HMGA1	3159	high mobility group AT-hook 1	positive regulation of cellular senescence	Biological process	16901784
BAD	572	BCL2-associated agonist of cell death	programmed cell death	Biological process	-
CTR9	9646	CTR9, Paf1/RNA polymerase II complex component	negative regulation of mRNA polyadenylation	Biological process	19575011
PSTPIP1	9051	proline-serine-threonine phosphatase interacting protein 1	stress fiber	Cellular component	-
BCL10	8915	B-cell CLL/lymphoma 10	protein binding	Molecular function	1040062
APOC2	344	apolipoprotein C-II	negative regulation of catalytic activity	Biological process	182536
GPS2	2874	G protein pathway suppressor 2	chromatin organization	Biological process	-
GABRR3	200959	gamma-aminobutyric acid (GABA) A receptor, rho 3 (gene/pseudogene)	chloride channel activity	Molecular function	-
SHANK1	50944	SH3 and multiple ankyrin repeat domains 1	associative learning	Biological process	-
RAB18	22931	RAB18, member RAS oncogene family	brain development	Biological process	-
ALOXE3	59344	arachidonate lipoxygenase 3	ceramide biosynthetic process	Biological process	-
SLC39A6	25800	solute carrier family 39 (zinc transporter), member 6	cell surface	Cellular component	19581412
ACTB	60	actin, beta	nucleoplasm	Cellular component	-
IRF3	3661	interferon regulatory factor 3	MDA-5 signaling pathway	Biological process	16979567
BMP5	653	bone morphogenetic protein 5	regulation of MAPK cascade	Biological process	-
EIF4ENIF1	56478	eukaryotic translation initiation factor 4E nuclear import factor 1	cytosol	Cellular component	-
SAP30BP	29115	SAP30 binding protein	regulation of transcription, DNA-templated	Biological process	-
TRPV5	56302	transient receptor potential cation channel, subfamily V, member 5	calcium ion transport	Biological process	15665527
PIEZO2	63895	piezo-type mechanosensitive ion channel component 2	cation channel activity	Molecular function	-
GTF2E2	2961	general transcription factor IIE, polypeptide 2, beta 34kDa	regulation of transcription, DNA-templated	Biological process	-
BSG	682	basigin (Ok blood group)	mannose binding	Molecular function	-
SYNE2	23224	spectrin repeat containing, nuclear envelope 2	cytoplasm	Cellular component	12118075
RELA	5970	v-rel avian reticuloendotheliosis viral oncogene homolog A	positive regulation of chondrocyte differentiation	Biological process	-
SEBOX	645832	SEBOX homeobox	molecular_function	Molecular function	-
FRAS1	80144	Fraser extracellular matrix complex subunit 1	plasma membrane	Cellular component	-
FOXO4	4303	forkhead box O4	fibroblast growth factor receptor signaling pathway	Biological process	-
CPQ	10404	carboxypeptidase Q	peptide catabolic process	Biological process	10206990
RAB2B	84932	RAB2B, member RAS oncogene family	intracellular protein transport	Biological process	-
FOXK1	221937	forkhead box K1	muscle organ development	Biological process	-
USP37	57695	ubiquitin specific peptidase 37	protein K48-linked deubiquitination	Biological process	21596315
CEP19	84984	centrosomal protein 19kDa	ciliary basal body	Cellular component	24268657
ABAT	18	4-aminobutyrate aminotransferase	neurotransmitter secretion	Biological process	-
PCDHB15	56121	protocadherin beta 15	cell adhesion	Biological process	10380929
PF4	5196	platelet factor 4	platelet alpha granule lumen	Cellular component	-
POC1B	282809	POC1 centriolar protein B	protein binding	Molecular function	23015594
ZFAND5	7763	zinc finger, AN1-type domain 5	fibroblast migration	Biological process	-
ITGA8	8516	integrin, alpha 8	inner ear morphogenesis	Biological process	-
TNFSF13	8741	tumor necrosis factor (ligand) superfamily, member 13	signal transduction	Biological process	9743536
BHLHB9	80823	basic helix-loop-helix domain containing, class B, 9	protein homodimerization activity	Molecular function	-
OR10W1	81341	olfactory receptor, family 10, subfamily W, member 1	G-protein coupled receptor activity	Molecular function	-
GRK4	2868	G protein-coupled receptor kinase 4	G-protein coupled receptor internalization	Biological process	-
NPR2	4882	natriuretic peptide receptor 2	hormone binding	Molecular function	1660465
MCM8	84515	minichromosome maintenance complex component 8	nucleoplasm	Cellular component	-
ERCC4	2072	excision repair cross-complementation group 4	single-stranded DNA binding	Molecular function	10413517
ATG7	10533	autophagy related 7	positive regulation of mucus secretion	Biological process	-
ABCB9	23457	ATP-binding cassette, sub-family B (MDR/TAP), member 9	antigen processing and presentation of peptide antigen via MHC class I	Biological process	17977821
MAPRE1	22919	microtubule-associated protein, RP/EB family, member 1	cortical microtubule cytoskeleton	Cellular component	15631994
ZP3	7784	zona pellucida glycoprotein 3 (sperm receptor)	intracellular protein transport	Biological process	-
NCAM1	4684	neural cell adhesion molecule 1	Golgi membrane	Cellular component	-
ALKBH3	221120	alkB, alkylation repair homolog 3 (E. coli)	cytoplasm	Cellular component	-
NAA35	60560	N(alpha)-acetyltransferase 35, NatC auxiliary subunit	protein binding	Molecular function	19398576
SALL1	6299	spalt-like transcription factor 1	inductive cell-cell signaling	Biological process	-
ZNF565	147929	zinc finger protein 565	DNA binding	Molecular function	-
RBL1	5933	retinoblastoma-like 1	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
RAD51C	5889	RAD51 paralog C	Rad51B-Rad51C-Rad51D-XRCC2 complex	Cellular component	11751635
CHRNB1	1140	cholinergic receptor, nicotinic, beta 1 (muscle)	signal transduction	Biological process	8872460
ATG4B	23192	autophagy related 4B, cysteine peptidase	cytosol	Cellular component	-
ELOVL6	79071	ELOVL fatty acid elongase 6	transferase activity, transferring acyl groups other than amino-acyl groups	Molecular function	-
RAB44	401258	RAB44, member RAS oncogene family	plasma membrane	Cellular component	-
NCF1	653361	neutrophil cytosolic factor 1	phosphatidylinositol binding	Molecular function	12356722
E2F1	1869	E2F transcription factor 1	cellular response to hypoxia	Biological process	-
PPARA	5465	peroxisome proliferator-activated receptor alpha	DNA binding	Molecular function	10860941
ELOVL1	64834	ELOVL fatty acid elongase 1	fatty acid elongation, saturated fatty acid	Biological process	20166112
HHIPL2	79802	HHIP-like 2	quinone binding	Molecular function	-
BAIAP2L1	55971	BAI1-associated protein 2-like 1	nucleoplasm	Cellular component	-
OR8A1	390275	olfactory receptor, family 8, subfamily A, member 1	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
PYCR2	29920	pyrroline-5-carboxylate reductase family, member 2	cytoplasm	Cellular component	-
THBS4	7060	thrombospondin 4	calcium ion binding	Molecular function	16246837
UTP23	84294	UTP23, small subunit (SSU) processome component, homolog (yeast)	small-subunit processome	Cellular component	-
EGFR	1956	epidermal growth factor receptor	AP-2 adaptor complex	Cellular component	14702346
SERPINA7	6906	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7	aging	Biological process	-
CYP2W1	54905	cytochrome P450, family 2, subfamily W, polypeptide 1	intracellular membrane-bounded organelle	Cellular component	-
RFNG	5986	RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	metal ion binding	Molecular function	-
CDC23	8697	cell division cycle 23	intracellular	Cellular component	-
SSH3	54961	slingshot protein phosphatase 3	protein tyrosine/serine/threonine phosphatase activity	Molecular function	-
LNPEP	4012	leucyl/cystinyl aminopeptidase	proteolysis	Biological process	-
RLIM	51132	ring finger protein, LIM domain interacting	random inactivation of X chromosome	Biological process	19945382
ACVRL1	94	activin A receptor type II-like 1	negative regulation of cell proliferation	Biological process	12453878
RABEP2	79874	rabaptin, RAB GTPase binding effector protein 2	early endosome	Cellular component	-
BOLL	66037	boule-like RNA-binding protein	nucleotide binding	Molecular function	-
MYOG	4656	myogenin (myogenic factor 4)	regulation of myoblast fusion	Biological process	-
CYLD	1540	cylindromatosis (turban tumor syndrome)	nucleoplasm	Cellular component	-
ATP6V0D1	9114	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1	protein complex binding	Molecular function	-
GFI1	2672	growth factor independent 1 transcription repressor	RNA polymerase II regulatory region sequence-specific DNA binding	Molecular function	-
RAF1	5894	Raf-1 proto-oncogene, serine/threonine kinase	MAP kinase kinase kinase activity	Molecular function	-
RAPH1	65059	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1	axon extension	Biological process	-
TRIM64C	646754	tripartite motif containing 64C	zinc ion binding	Molecular function	-
FGD1	2245	FYVE, RhoGEF and PH domain containing 1	positive regulation of apoptotic process	Biological process	-
ADGRE5	976	adhesion G protein-coupled receptor E5	plasma membrane	Cellular component	-
UBA52	7311	ubiquitin A-52 residue ribosomal protein fusion product 1	nucleoplasm	Cellular component	-
KIAA0368	23392	KIAA0368	multivesicular body	Cellular component	20682791
SV2A	9900	synaptic vesicle glycoprotein 2A	synaptic vesicle membrane	Cellular component	-
EIF2B3	8891	eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa	protein binding	Molecular function	15060152
FOXP3	50943	forkhead box P3	negative regulation of sequence-specific DNA binding transcription factor activity	Biological process	16873067
UCHL5	51377	ubiquitin carboxyl-terminal hydrolase L5	ubiquitin-specific protease activity	Molecular function	18922472
ESYT2	57488	extended synaptotagmin-like protein 2	calcium-dependent phospholipid binding	Molecular function	17360437
HMP19	51617	HMP19 protein	clathrin coat assembly	Biological process	-
RLIM	51132	ring finger protein, LIM domain interacting	ubiquitin-dependent protein catabolic process	Biological process	-
ATG5	9474	autophagy related 5	autophagosome	Cellular component	15292400
CYTH1	9267	cytohesin 1	bicellular tight junction	Cellular component	-
AGAP3	116988	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3	cellular response to reactive oxygen species	Biological process	-
NOB1	28987	NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)	metal ion binding	Molecular function	-
LRAT	9227	lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)	endoplasmic reticulum membrane	Cellular component	-
TRIM34	53840	tripartite motif containing 34	cytosol	Cellular component	-
PDE3B	5140	phosphodiesterase 3B, cGMP-inhibited	negative regulation of cAMP-mediated signaling	Biological process	17884339
ATP5G1	516	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)	lipid binding	Molecular function	-
SRRM2	23524	serine/arginine repetitive matrix 2	catalytic step 2 spliceosome	Cellular component	11991638
C1QL1	10882	complement component 1, q subcomponent-like 1	cellular_component	Cellular component	-
NOTCH1	4851	notch 1	negative regulation of neurogenesis	Biological process	-
PAX6	5080	paired box 6	positive regulation of glucagon secretion	Biological process	-
HDAC4	9759	histone deacetylase 4	transcriptional repressor complex	Cellular component	11804585
SOX15	6665	SRY (sex determining region Y)-box 15	regulation of transcription, DNA-templated	Biological process	8332506
TLX2	3196	T-cell leukemia homeobox 2	molecular_function	Molecular function	-
UTP6	55813	UTP6, small subunit (SSU) processome component, homolog (yeast)	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Biological process	-
PREP	5550	prolyl endopeptidase	serine-type endopeptidase activity	Molecular function	-
ATAD3B	83858	ATPase family, AAA domain containing 3B	ATP binding	Molecular function	-
VAV3	10451	vav 3 guanine nucleotide exchange factor	vesicle fusion	Biological process	-
CFD	1675	complement factor D (adipsin)	platelet activation	Biological process	-
VCX	26609	variable charge, X-linked	ribosome assembly	Biological process	12862317
PSMC3IP	29893	PSMC3 interacting protein	DNA recombination	Biological process	-
CNOT10	25904	CCR4-NOT transcription complex, subunit 10	cytosol	Cellular component	-
GADD45B	4616	growth arrest and DNA-damage-inducible, beta	protein binding	Molecular function	12052864
RIPK2	8767	receptor-interacting serine-threonine kinase 2	positive regulation of T-helper 1 cell differentiation	Biological process	-
GAPDH	2597	glyceraldehyde-3-phosphate dehydrogenase	carbohydrate metabolic process	Biological process	-
BGLAP	632	bone gamma-carboxyglutamate (gla) protein	response to estrogen	Biological process	-
FOXC1	2296	forkhead box C1	glycosaminoglycan metabolic process	Biological process	-
LRRFIP1	9208	leucine rich repeat (in FLII) interacting protein 1	regulation of transcription from RNA polymerase II promoter	Biological process	9705290
ZNF728	388523	zinc finger protein 728	regulation of transcription, DNA-templated	Biological process	-
RAB32	10981	RAB32, member RAS oncogene family	metabolic process	Biological process	21808068
LSM4	25804	LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	Biological process	-
SPTBN1	6711	spectrin, beta, non-erythrocytic 1	protein binding	Molecular function	12820899
COPS2	9318	COP9 signalosome subunit 2	skeletal muscle cell differentiation	Biological process	-
FAM175A	84142	family with sequence similarity 175, member A	polyubiquitin binding	Molecular function	19261749
FLRT2	23768	fibronectin leucine rich transmembrane protein 2	regulation of neuron migration	Biological process	-
INTS4	92105	integrator complex subunit 4	protein binding	Molecular function	16239144
HDAC10	83933	histone deacetylase 10	oligodendrocyte development	Biological process	-
DHX33	56919	DEAH (Asp-Glu-Ala-His) box polypeptide 33	cytoplasm	Cellular component	-
NSF	4905	N-ethylmaleimide-sensitive factor	potassium ion transport	Biological process	-
PECR	55825	peroxisomal trans-2-enoyl-CoA reductase	phytol metabolic process	Biological process	16546181
ZBTB16	7704	zinc finger and BTB domain containing 16	negative regulation of transcription from RNA polymerase II promoter	Biological process	12802276
RBMS2	5939	RNA binding motif, single stranded interacting protein 2	poly(A) RNA binding	Molecular function	22658674
AMPD3	272	adenosine monophosphate deaminase 3	AMP deaminase activity	Molecular function	-
CD101	9398	CD101 molecule	positive regulation of myeloid leukocyte differentiation	Biological process	-
POM121	9883	POM121 transmembrane nucleoporin	protein transport	Biological process	-
MYC	4609	v-myc avian myelocytomatosis viral oncogene homolog	transcription initiation from RNA polymerase II promoter	Biological process	-
HSD11B1L	374875	hydroxysteroid (11-beta) dehydrogenase 1-like	oxidation-reduction process	Biological process	-
ABL2	27	ABL proto-oncogene 2, non-receptor tyrosine kinase	signal transduction	Biological process	2198571
RPS6KB2	6199	ribosomal protein S6 kinase, 70kDa, polypeptide 2	phosphatidylinositol-mediated signaling	Biological process	-
FOS	2353	FBJ murine osteosarcoma viral oncogene homolog	response to progesterone	Biological process	-
THPO	7066	thrombopoietin	extracellular space	Cellular component	-
SMG1	23049	SMG1 phosphatidylinositol 3-kinase-related kinase	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Biological process	16488880
NHLRC1	378884	NHL repeat containing E3 ubiquitin protein ligase 1	cytosol	Cellular component	-
POLR2E	5434	polymerase (RNA) II (DNA directed) polypeptide E, 25kDa	transcription initiation from RNA polymerase II promoter	Biological process	-
OSTN	344901	osteocrin	cell surface receptor signaling pathway	Biological process	-
STARD10	10809	StAR-related lipid transfer (START) domain containing 10	protein binding	Molecular function	23455924
ZNF555	148254	zinc finger protein 555	DNA binding	Molecular function	-
UBE2O	63893	ubiquitin-conjugating enzyme E2O	protein monoubiquitination	Biological process	23455153
AKNA	80709	AT-hook transcription factor	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	11268217
GDF7	151449	growth differentiation factor 7	roof plate formation	Biological process	-
SLC6A12	6539	solute carrier family 6 (neurotransmitter transporter), member 12	neurotransmitter secretion	Biological process	-
C1orf43	25912	chromosome 1 open reading frame 43	oxidation-reduction process	Biological process	-
SLC22A31	146429	solute carrier family 22, member 31	transmembrane transporter activity	Molecular function	-
GJB2	2706	gap junction protein, beta 2, 26kDa	connexon complex	Cellular component	-
KCNE3	10008	potassium channel, voltage gated subfamily E regulatory beta subunit 3	negative regulation of delayed rectifier potassium channel activity	Biological process	12954870
ABHD17C	58489	abhydrolase domain containing 17C	metabolic process	Biological process	-
ALDH3A1	218	aldehyde dehydrogenase 3 family, member A1	extracellular space	Cellular component	22664934
NUDT1	4521	nudix (nucleoside diphosphate linked moiety X)-type motif 1	DNA protection	Biological process	10608900
TC2N	123036	tandem C2 domains, nuclear	clathrin binding	Molecular function	-
YWHAE	7531	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon	ubiquitin protein ligase binding	Molecular function	19725078
SCARB1	949	scavenger receptor class B, member 1	positive regulation of triglyceride biosynthetic process	Biological process	-
JAK3	3718	Janus kinase 3	JAK-STAT cascade involved in growth hormone signaling pathway	Biological process	19290934
WNT6	7475	wingless-type MMTV integration site family, member 6	positive regulation of transcription, DNA-templated	Biological process	-
STK26	51765	serine/threonine protein kinase 26	apical plasma membrane	Cellular component	22797597
CALM2	805	calmodulin 2 (phosphorylase kinase, delta)	phototransduction, visible light	Biological process	-
PTPN23	25930	protein tyrosine phosphatase, non-receptor type 23	ciliary basal body	Cellular component	20393563
HAMP	57817	hepcidin antimicrobial peptide	apical cortex	Cellular component	-
GPD1	2819	glycerol-3-phosphate dehydrogenase 1 (soluble)	cellular lipid metabolic process	Biological process	-
CCNDBP1	23582	cyclin D-type binding-protein 1	cytoplasm	Cellular component	-
SH3GL3	6457	SH3-domain GRB2-like 3	signal transduction	Biological process	9169142
OGDHL	55753	oxoglutarate dehydrogenase-like	mitochondrion	Cellular component	-
UGT2B28	54490	UDP glucuronosyltransferase 2 family, polypeptide B28	metabolic process	Biological process	11300766
CBR3	874	carbonyl reductase 3	nucleoplasm	Cellular component	-
EPC1	80314	enhancer of polycomb homolog 1 (Drosophila)	negative regulation of transcription from RNA polymerase II promoter	Biological process	10976108
LONP1	9361	lon peptidase 1, mitochondrial	mitochondrial nucleoid	Cellular component	18063578
FGFR3	2261	fibroblast growth factor receptor 3	integral component of plasma membrane	Cellular component	8663044
TNN	63923	tenascin N	integrin binding	Molecular function	-
GIPC1	10755	GIPC PDZ domain containing family, member 1	synaptic vesicle	Cellular component	-
EIF3J	8669	eukaryotic translation initiation factor 3, subunit J	translational initiation	Biological process	-
HIST1H3F	8968	histone cluster 1, H3f	negative regulation of gene expression, epigenetic	Biological process	-
GRB10	2887	growth factor receptor-bound protein 10	cytoplasm	Cellular component	9006901
CHRM1	1128	cholinergic receptor, muscarinic 1	axon terminus	Cellular component	-
ERI3	79033	ERI1 exoribonuclease family member 3	exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Biological process	-
P2RX4	5025	purinergic receptor P2X, ligand gated ion channel, 4	membrane	Cellular component	17785580
CRYM	1428	crystallin, mu	negative regulation of transcription from RNA polymerase II promoter	Biological process	11897713
ERBB3	2065	erb-b2 receptor tyrosine kinase 3	growth factor binding	Molecular function	7514177
ZNF789	285989	zinc finger protein 789	metal ion binding	Molecular function	-
PGF	5228	placental growth factor	membrane	Cellular component	-
AGRP	181	agouti related neuropeptide	Golgi lumen	Cellular component	15927146
RPS12	6206	ribosomal protein S12	SRP-dependent cotranslational protein targeting to membrane	Biological process	-
TCF7L2	6934	transcription factor 7-like 2 (T-cell specific, HMG-box)	insulin metabolic process	Biological process	-
SOX17	64321	SRY (sex determining region Y)-box 17	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
ALKBH2	121642	alkB, alkylation repair homolog 2 (E. coli)	oxidative demethylation	Biological process	18775698
RFT1	91869	RFT1 homolog (S. cerevisiae)	glycolipid translocation	Biological process	-
GNG7	2788	guanine nucleotide binding protein (G protein), gamma 7	cellular response to glucagon stimulus	Biological process	-
MUC20	200958	mucin 20, cell surface associated	apical plasma membrane	Cellular component	-
RXFP4	339403	relaxin/insulin-like family peptide receptor 4	angiotensin type II receptor activity	Molecular function	-
PITPNA	5306	phosphatidylinositol transfer protein, alpha	phospholipid transport	Biological process	8194769
ARRB2	409	arrestin, beta 2	follicle-stimulating hormone receptor binding	Molecular function	-
CORO2B	10391	coronin, actin binding protein, 2B	actin filament binding	Molecular function	-
PHF21B	112885	PHD finger protein 21B	zinc ion binding	Molecular function	-
NAPRT	93100	nicotinate phosphoribosyltransferase	extracellular exosome	Cellular component	19056867
DCN	1634	decorin	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan	Biological process	-
KRT8	3856	keratin 8, type II	dystrophin-associated glycoprotein complex	Cellular component	-
STAT3	6774	signal transducer and activator of transcription 3 (acute-phase response factor)	protein binding	Molecular function	10688651
PSMD1	5707	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	nucleoplasm	Cellular component	-
ABHD16B	140701	abhydrolase domain containing 16B	hydrolase activity	Molecular function	-
UTP11L	51118	UTP11-like, U3 small nucleolar ribonucleoprotein (yeast)	poly(A) RNA binding	Molecular function	22658674
IL2	3558	interleukin 2	positive regulation of interferon-gamma production	Biological process	-
TMOD3	29766	tropomodulin 3 (ubiquitous)	pointed-end actin filament capping	Biological process	-
IL6ST	3572	interleukin 6 signal transducer	oncostatin-M-mediated signaling pathway	Biological process	8999038
DSP	1832	desmoplakin	protein kinase C binding	Molecular function	18474624
CLSTN2	64084	calsyntenin 2	homophilic cell adhesion via plasma membrane adhesion molecules	Biological process	-
PICK1	9463	protein interacting with PRKCA 1	protein targeting	Biological process	-
THOC5	8563	THO complex 5	primitive hemopoiesis	Biological process	-
CLCN3	1182	chloride channel, voltage-sensitive 3	integral component of membrane	Cellular component	12471024
JAK2	3717	Janus kinase 2	interleukin-12 receptor binding	Molecular function	-
NSD1	64324	nuclear receptor binding SET domain protein 1	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
MCM2	4171	minichromosome maintenance complex component 2	cytoplasm	Cellular component	-
PTK2	5747	protein tyrosine kinase 2	positive regulation of cell migration	Biological process	11331870
PPP1R26	9858	protein phosphatase 1, regulatory subunit 26	negative regulation of phosphatase activity	Biological process	19389623
EGLN3	112399	egl-9 family hypoxia-inducible factor 3	nucleoplasm	Cellular component	-
INIP	58493	INTS3 and NABP interacting protein	nucleus	Cellular component	19605351
APAF1	317	apoptotic peptidase activating factor 1	protein binding	Molecular function	10206961
SOX2	6657	SRY (sex determining region Y)-box 2	transcription from RNA polymerase II promoter	Biological process	-
LAT2	7462	linker for activation of T cells family, member 2	plasma membrane	Cellular component	-
ZNF705A	440077	zinc finger protein 705A	nucleus	Cellular component	-
NDUFA7	4701	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa	respiratory electron transport chain	Biological process	-
SLC11A2	4891	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2	copper ion binding	Molecular function	-
ATP2B4	493	ATPase, Ca++ transporting, plasma membrane 4	negative regulation of calcineurin-NFAT signaling cascade	Biological process	19287093
ITGA7	3679	integrin, alpha 7	cell surface	Cellular component	20563599
GPR50	9248	G protein-coupled receptor 50	cell-cell signaling	Biological process	8647286
TNIK	23043	TRAF2 and NCK interacting kinase	protein binding	Molecular function	10521462
CNOT7	29883	CCR4-NOT transcription complex, subunit 7	poly(A)-specific ribonuclease activity	Molecular function	15769875
PSMD12	5718	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	G1/S transition of mitotic cell cycle	Biological process	-
AGAP5	729092	ArfGAP with GTPase domain, ankyrin repeat and PH domain 5	positive regulation of GTPase activity	Biological process	-
MDK	4192	midkine (neurite growth-promoting factor 2)	short-term memory	Biological process	-
RGS19	10287	regulator of G-protein signaling 19	heterotrimeric G-protein complex	Cellular component	8524874
SNRPD3	6634	small nuclear ribonucleoprotein D3 polypeptide 18kDa	spliceosomal snRNP assembly	Biological process	-
NOTCH1	4851	notch 1	prostate gland epithelium morphogenesis	Biological process	-
RARA	5914	retinoic acid receptor, alpha	response to cytokine	Biological process	-
IST1	9798	increased sodium tolerance 1 homolog (yeast)	cytoplasmic membrane-bounded vesicle	Cellular component	-
DAXX	1616	death-domain associated protein	mitotic cytokinesis	Biological process	-
ZGPAT	84619	zinc finger, CCCH-type with G patch domain	sequence-specific DNA binding transcription factor activity	Molecular function	19644445
PML	5371	promyelocytic leukemia	transcription, DNA-templated	Biological process	-
REXO1L1P	254958	REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 1, pseudogene	nucleic acid phosphodiester bond hydrolysis	Biological process	-
TGM1	7051	transglutaminase 1	keratinization	Biological process	-
PKNOX1	5316	PBX/knotted 1 homeobox 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
POP1	10940	processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)	tRNA processing	Biological process	-
NRP2	8828	neuropilin 2	cell adhesion	Biological process	11112349
DHRS3	9249	dehydrogenase/reductase (SDR family) member 3	electron carrier activity	Molecular function	9705317
MOB4	25843	MOB family member 4, phocein	protein binding	Molecular function	18782753
AURKA	6790	aurora kinase A	cell division	Biological process	-
CWF19L1	55280	CWF19-like 1, cell cycle control (S. pombe)	metabolic process	Biological process	-
APC	324	adenomatous polyposis coli	regulation of microtubule-based process	Biological process	20937854
TRIM22	10346	tripartite motif containing 22	regulation of transcription, DNA-templated	Biological process	7797467
YBX3	8531	Y box binding protein 3	cellular response to tumor necrosis factor	Biological process	22711822
HSD17B1	3292	hydroxysteroid (17-beta) dehydrogenase 1	nuclear membrane	Cellular component	-
WNT9A	7483	wingless-type MMTV integration site family, member 9A	embryonic skeletal joint development	Biological process	-
MMP1	4312	matrix metallopeptidase 1	proteolysis	Biological process	15863497
ENPP6	133121	ectonucleotide pyrophosphatase/phosphodiesterase 6	choline metabolic process	Biological process	15788404
SNX30	401548	sorting nexin family member 30	endosome	Cellular component	-
STS	412	steroid sulfatase (microsomal), isozyme S	endoplasmic reticulum lumen	Cellular component	-
GFM1	85476	G elongation factor, mitochondrial 1	mitochondrial translational elongation	Biological process	-
ATR	545	ATR serine/threonine kinase	DNA damage checkpoint	Biological process	14657349
PEX1	5189	peroxisomal biogenesis factor 1	protein import into peroxisome matrix	Biological process	9398847
ADA	100	adenosine deaminase	positive regulation of alpha-beta T cell differentiation	Biological process	-
DEFB4A	1673	defensin, beta 4A	immune response	Biological process	10521347
PHRF1	57661	PHD and ring finger domains 1	transcription from RNA polymerase II promoter	Biological process	-
CFP	5199	complement factor properdin	complement activation	Biological process	-
NUP188	23511	nucleoporin 188kDa	protein transport	Biological process	-
SULT1C2	6819	sulfotransferase family, cytosolic, 1C, member 2	small molecule metabolic process	Biological process	-
HOXA5	3202	homeobox A5	cell migration	Biological process	-
BMX	660	BMX non-receptor tyrosine kinase	protein autophosphorylation	Biological process	11331870
PGF	5228	placental growth factor	response to drug	Biological process	-
AKR1C3	8644	aldo-keto reductase family 1, member C3	positive regulation of cell proliferation	Biological process	21851338
BMP7	655	bone morphogenetic protein 7	extracellular region	Cellular component	-
EFNB2	1948	ephrin-B2	lymph vessel development	Biological process	-
PLEKHO1	51177	pleckstrin homology domain containing, family O member 1	cytoplasm	Cellular component	-
HMGB3	3149	high mobility group box 3	regulation of transcription, DNA-templated	Biological process	-
ATP6V1C1	528	ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1	plasma membrane	Cellular component	-
LIPA	3988	lipase A, lysosomal acid, cholesterol esterase	cell morphogenesis	Biological process	-
VIPR1	7433	vasoactive intestinal peptide receptor 1	G-protein coupled receptor signaling pathway	Biological process	8179610
MAP3K1	4214	mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase	protein kinase binding	Molecular function	17906693
LEAP2	116842	liver expressed antimicrobial peptide 2	defense response to bacterium	Biological process	-
HLA-E	3133	major histocompatibility complex, class I, E	plasma membrane	Cellular component	-
RNF2	6045	ring finger protein 2	ubiquitin-protein transferase activity	Molecular function	16714294
TGFB3	7043	transforming growth factor, beta 3	platelet degranulation	Biological process	-
JDP2	122953	Jun dimerization protein 2	positive regulation of histone deacetylation	Biological process	-
EIF3L	51386	eukaryotic translation initiation factor 3, subunit L	poly(A) RNA binding	Molecular function	22658674
USP10	9100	ubiquitin specific peptidase 10	early endosome	Cellular component	19398555
ATP1B1	481	ATPase, Na+/K+ transporting, beta 1 polypeptide	sodium:potassium-exchanging ATPase complex	Cellular component	10636900
RSAD2	91543	radical S-adenosyl methionine domain containing 2	defense response to virus	Biological process	16108059
ADORA2B	136	adenosine A2b receptor	adenosine receptor signaling pathway	Biological process	-
HAND2	9464	heart and neural crest derivatives expressed 2	negative regulation of DNA binding	Biological process	-
ZBTB18	10472	zinc finger and BTB domain containing 18	nuclear chromosome	Cellular component	9756912
EIF2D	1939	eukaryotic translation initiation factor 2D	ribosome disassembly	Biological process	20713520
JADE2	23338	jade family PHD finger 2	zinc ion binding	Molecular function	-
AK1	203	adenylate kinase 1	plasma membrane	Cellular component	-
USP9Y	8287	ubiquitin specific peptidase 9, Y-linked	protein deubiquitination	Biological process	-
PRL	5617	prolactin	lactation	Biological process	-
ACSL5	51703	acyl-CoA synthetase long-chain family member 5	mitochondrion	Cellular component	-
ZMIZ2	83637	zinc finger, MIZ-type containing 2	zinc ion binding	Molecular function	-
PSMF1	9491	proteasome (prosome, macropain) inhibitor subunit 1 (PI31)	small molecule metabolic process	Biological process	-
PPFIA3	8541	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3	presynaptic active zone	Cellular component	15217342
SDHA	6389	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	oxidation-reduction process	Biological process	7550341
DAPP1	27071	dual adaptor of phosphotyrosine and 3-phosphoinositides	protein binding	Molecular function	25814554
MAP6	4135	microtubule-associated protein 6	protein binding	Molecular function	24357581
NEU1	4758	sialidase 1 (lysosomal sialidase)	exo-alpha-sialidase activity	Molecular function	8985184
APIP	51074	APAF1 interacting protein	sulfur amino acid metabolic process	Biological process	-
FANCI	55215	Fanconi anemia, complementation group I	plasma membrane	Cellular component	-
SMTNL1	219537	smoothelin-like 1	I band	Cellular component	-
SPIC	121599	Spi-C transcription factor (Spi-1/PU.1 related)	blastocyst development	Biological process	-
NRG4	145957	neuregulin 4	growth factor activity	Molecular function	-
APP	351	amyloid beta (A4) precursor protein	synapse	Cellular component	11988176
HMGCR	3156	3-hydroxy-3-methylglutaryl-CoA reductase	visual learning	Biological process	-
STOML2	30968	stomatin (EPB72)-like 2	mitochondrial calcium ion transport	Biological process	19944461
OBFC1	79991	oligonucleotide/oligosaccharide-binding fold containing 1	single-stranded telomeric DNA binding	Molecular function	19648609
IDH3G	3421	isocitrate dehydrogenase 3 (NAD+) gamma	isocitrate metabolic process	Biological process	-
P2RX2	22953	purinergic receptor P2X, ligand gated ion channel, 2	integral component of nuclear inner membrane	Cellular component	-
CFH	3075	complement factor H	complement activation	Biological process	9312129
TBC1D10A	83874	TBC1 domain family, member 10A	microvillus	Cellular component	11285285
CACNB3	784	calcium channel, voltage-dependent, beta 3 subunit	synaptic transmission	Biological process	-
ATRX	546	alpha thalassemia/mental retardation syndrome X-linked	seminiferous tubule development	Biological process	-
PAWR	5074	PRKC, apoptosis, WT1, regulator	negative regulation of T cell proliferation	Biological process	-
VCAM1	7412	vascular cell adhesion molecule 1	primary amine oxidase activity	Molecular function	23474851
TSHZ3	57616	teashirt zinc finger homeobox 3	chromatin binding	Molecular function	19343227
OMG	4974	oligodendrocyte myelin glycoprotein	neurotrophin TRK receptor signaling pathway	Biological process	-
TMEM68	137695	transmembrane protein 68	transferase activity, transferring acyl groups	Molecular function	-
CAMK2D	817	calcium/calmodulin-dependent protein kinase II delta	sodium channel inhibitor activity	Molecular function	22514276
EMG1	10436	EMG1 N1-specific pseudouridine methyltransferase	RNA binding	Molecular function	-
FGFR2	2263	fibroblast growth factor receptor 2	multicellular organism growth	Biological process	-
SNX10	29887	sorting nexin 10	1-phosphatidylinositol binding	Molecular function	17012226
SPEM1	374768	spermatid maturation 1	sperm individualization	Biological process	-
ZNF658	26149	zinc finger protein 658	DNA binding	Molecular function	-
FERMT2	10979	fermitin family member 2	cell-matrix adhesion	Biological process	-
SUPV3L1	6832	suppressor of var1, 3-like 1 (S. cerevisiae)	mitochondrion morphogenesis	Biological process	19864255
DOCK6	57572	dedicator of cytokinesis 6	cytosol	Cellular component	-
MED17	9440	mediator complex subunit 17	intracellular steroid hormone receptor signaling pathway	Biological process	11867769
DHX38	9785	DEAH (Asp-Glu-Ala-His) box polypeptide 38	RNA splicing	Biological process	-
SNAP25	6616	synaptosomal-associated protein, 25kDa	syntaxin-1 binding	Molecular function	12730201
AP2A2	161	adaptor-related protein complex 2, alpha 2 subunit	ephrin receptor signaling pathway	Biological process	-
GDF11	10220	growth differentiation factor 11	metanephros development	Biological process	-
MPP7	143098	membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)	positive regulation of signal transduction	Biological process	20702775
TOP1	7150	topoisomerase (DNA) I	phosphorylation	Biological process	17481653
SCN3B	55800	sodium channel, voltage gated, type III beta subunit	ion channel binding	Molecular function	20042427
PDLIM3	27295	PDZ and LIM domain 3	zinc ion binding	Molecular function	-
TSPO	706	translocator protein (18kDa)	intracellular membrane-bounded organelle	Cellular component	-
OR1D4	653166	olfactory receptor, family 1, subfamily D, member 4 (gene/pseudogene)	sensory perception of chemical stimulus	Biological process	8004088
KLF10	7071	Kruppel-like factor 10	negative regulation of cell proliferation	Biological process	9748269
PRKCSH	5589	protein kinase C substrate 80K-H	N-glycan processing	Biological process	-
PCNA	5111	proliferating cell nuclear antigen	nucleotide-excision repair, DNA gap filling	Biological process	-
POLH	5429	polymerase (DNA directed), eta	nucleoplasm	Cellular component	-
SMOX	54498	spermine oxidase	cytosol	Cellular component	-
HDAC5	10014	histone deacetylase 5	negative regulation of cell migration involved in sprouting angiogenesis	Biological process	19351956
CASP8AP2	9994	caspase 8 associated protein 2	negative regulation of nucleic acid-templated transcription	Biological process	12477726
B3GALT6	126792	UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6	membrane	Cellular component	19946888
GHRL	51738	ghrelin/obestatin prepropeptide	growth hormone-releasing hormone activity	Molecular function	16511605
LSAMP	4045	limbic system-associated membrane protein	protein binding	Molecular function	21982860
RBM39	9584	RNA binding motif protein 39	nuclear speck	Cellular component	-
IMPAD1	54928	inositol monophosphatase domain containing 1	inositol biosynthetic process	Biological process	-
CLK2	1196	CDC-like kinase 2	protein tyrosine kinase activity	Molecular function	-
STAT5B	6777	signal transducer and activator of transcription 5B	nucleus	Cellular component	-
PSMD13	5719	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition	Biological process	-
ADAM8	101	ADAM metallopeptidase domain 8	extracellular matrix organization	Biological process	-
ENTPD3	956	ectonucleoside triphosphate diphosphohydrolase 3	integral component of membrane	Cellular component	-
GSX2	170825	GS homeobox 2	sequence-specific DNA binding	Molecular function	-
SIX3	6496	SIX homeobox 3	visual perception	Biological process	10369266
CALM1	801	calmodulin 1 (phosphorylase kinase, delta)	membrane organization	Biological process	-
MIEF2	125170	mitochondrial elongation factor 2	mitochondrion	Cellular component	23921378
ISG20	3669	interferon stimulated exonuclease gene 20kDa	nucleoplasm	Cellular component	-
BCL2L11	10018	BCL2-like 11 (apoptosis facilitator)	kidney development	Biological process	-
KRT13	3860	keratin 13, type I	cellular response to retinoic acid	Biological process	-
EIF4EBP2	1979	eukaryotic translation initiation factor 4E binding protein 2	eukaryotic initiation factor 4E binding	Molecular function	-
LY9	4063	lymphocyte antigen 9	integral component of membrane	Cellular component	-
PRKACA	5566	protein kinase, cAMP-dependent, catalytic, alpha	cellular response to epinephrine stimulus	Biological process	23507255
SNRPD1	6632	small nuclear ribonucleoprotein D1 polypeptide 16kDa	mRNA splicing, via spliceosome	Biological process	-
MYO1D	4642	myosin ID	apical dendrite	Cellular component	-
TTYH2	94015	tweety family member 2	plasma membrane	Cellular component	-
PRKCZ	5590	protein kinase C, zeta	platelet activation	Biological process	-
CD24	100133941	CD24 molecule	B cell receptor transport into membrane raft	Biological process	11313396
RELN	5649	reelin	lipoprotein particle receptor binding	Molecular function	10571240
ITPR2	3709	inositol 1,4,5-trisphosphate receptor, type 2	regulation of insulin secretion	Biological process	-
SCGB3A2	117156	secretoglobin, family 3A, member 2	receptor-mediated endocytosis	Biological process	-
GALNTL6	442117	polypeptide N-acetylgalactosaminyltransferase-like 6	Golgi membrane	Cellular component	-
NR1H3	10062	nuclear receptor subfamily 1, group H, member 3	cholesterol homeostasis	Biological process	-
FGR	2268	FGR proto-oncogene, Src family tyrosine kinase	phosphotyrosine binding	Molecular function	-
LINGO4	339398	leucine rich repeat and Ig domain containing 4	integral component of membrane	Cellular component	-
USP17L5	728386	ubiquitin specific peptidase 17-like family member 5	protein deubiquitination	Biological process	-
RCHY1	25898	ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase	DNA repair	Biological process	-
OPA1	4976	optic atrophy 1 (autosomal dominant)	cellular senescence	Biological process	17545159
INPPL1	3636	inositol polyphosphate phosphatase-like 1	endochondral ossification	Biological process	23273569
POLR3G	10622	polymerase (RNA) III (DNA directed) polypeptide G (32kD)	positive regulation of type I interferon production	Biological process	-
STK40	83931	serine/threonine kinase 40	lung alveolus development	Biological process	-
CCT7	10574	chaperonin containing TCP1, subunit 7 (eta)	'de novo' posttranslational protein folding	Biological process	-
HSPA2	3306	heat shock 70kDa protein 2	cell surface	Cellular component	-
S1PR4	8698	sphingosine-1-phosphate receptor 4	immune response	Biological process	9790765
L1RE1	4029	LINE1 retrotransposable element 1	cytoplasmic stress granule	Cellular component	17562864
HEXB	3074	hexosaminidase B (beta polypeptide)	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
XRCC2	7516	X-ray repair complementing defective repair in Chinese hamster cells 2	mitotic cell cycle	Biological process	21276791
AR	367	androgen receptor	steroid hormone mediated signaling pathway	Biological process	-
AMBP	259	alpha-1-microglobulin/bikunin precursor	heme binding	Molecular function	11877257
OAZ1	4946	ornithine decarboxylase antizyme 1	negative regulation of polyamine transmembrane transport	Biological process	-
MYH9	4627	myosin, heavy chain 9, non-muscle	protein binding	Molecular function	10822899
TMEM126B	55863	transmembrane protein 126B	molecular_function	Molecular function	-
DDX27	55661	DEAD (Asp-Glu-Ala-Asp) box polypeptide 27	RNA secondary structure unwinding	Biological process	-
GPC1	2817	glypican 1	retinoid metabolic process	Biological process	-
SYNM	23336	synemin, intermediate filament protein	intermediate filament	Cellular component	11353857
LDLR	3949	low density lipoprotein receptor	glycoprotein binding	Molecular function	10571240
AP2A2	161	adaptor-related protein complex 2, alpha 2 subunit	viral process	Biological process	-
NFATC4	4776	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	transcription factor complex	Cellular component	-
ATP6V0A1	535	ATPase, H+ transporting, lysosomal V0 subunit a1	ion transmembrane transport	Biological process	-
PSMD5	5711	proteasome (prosome, macropain) 26S subunit, non-ATPase, 5	gene expression	Biological process	-
RNF5	6048	ring finger protein 5, E3 ubiquitin protein ligase	protein binding	Molecular function	12861019
HLA-DPA1	3113	major histocompatibility complex, class II, DP alpha 1	lysosomal membrane	Cellular component	-
KYNU	8942	kynureninase	L-kynurenine catabolic process	Biological process	-
CIITA	4261	class II, major histocompatibility complex, transactivator	cytokine-mediated signaling pathway	Biological process	-
TRAF2	7186	TNF receptor-associated factor 2	ubiquitin ligase complex	Cellular component	17314283
AQP8	343	aquaporin 8	intracellular canaliculus	Cellular component	-
DVL3	1857	dishevelled segment polarity protein 3	receptor binding	Molecular function	17030191
COL5A1	1289	collagen, type V, alpha 1	regulation of cellular component organization	Biological process	-
SYNM	23336	synemin, intermediate filament protein	intermediate filament binding	Molecular function	-
CD5	921	CD5 molecule	transmembrane signaling receptor activity	Molecular function	3093892
UPF3A	65110	UPF3 regulator of nonsense transcripts homolog A (yeast)	nucleotide binding	Molecular function	-
HIST2H2BF	440689	histone cluster 2, H2bf	extracellular exosome	Cellular component	19056867
ACE	1636	angiotensin I converting enzyme	regulation of systemic arterial blood pressure by renin-angiotensin	Biological process	174834
DYNC1H1	1778	dynein, cytoplasmic 1, heavy chain 1	dynein light intermediate chain binding	Molecular function	-
PTH1R	5745	parathyroid hormone 1 receptor	G-protein coupled receptor signaling pathway	Biological process	9745456
GGT1	2678	gamma-glutamyltransferase 1	extracellular space	Cellular component	16502470
ARC	23237	activity-regulated cytoskeleton-associated protein	learning	Biological process	-
ZNF780B	163131	zinc finger protein 780B	regulation of transcription, DNA-templated	Biological process	-
CLIC4	25932	chloride intracellular channel 4	protein binding	Molecular function	10793131
OTUD5	55593	OTU deubiquitinase 5	cytosol	Cellular component	-
NOTUM	147111	notum pectinacetylesterase homolog (Drosophila)	Wnt signaling pathway	Biological process	-
CLEC7A	64581	C-type lectin domain family 7, member A	signaling pattern recognition receptor activity	Molecular function	11567029
CDK8	1024	cyclin-dependent kinase 8	Notch signaling pathway	Biological process	-
FANCA	2175	Fanconi anemia, complementation group A	male gonad development	Biological process	-
AP2B1	163	adaptor-related protein complex 2, beta 1 subunit	viral process	Biological process	-
OAS3	4940	2'-5'-oligoadenylate synthetase 3, 100kDa	extracellular space	Cellular component	23580065
RAF1	5894	Raf-1 proto-oncogene, serine/threonine kinase	axon guidance	Biological process	-
ITM2B	9445	integral membrane protein 2B	Golgi-associated vesicle membrane	Cellular component	17965014
YWHAB	7529	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta	activation of MAPKK activity	Biological process	-
ILF2	3608	interleukin enhancer binding factor 2	poly(A) RNA binding	Molecular function	22658674
PSMD7	5713	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	mitotic cell cycle	Biological process	-
SEMA4C	54910	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C	postsynaptic density	Cellular component	-
USP8	9101	ubiquitin specific peptidase 8	ubiquitin-specific protease activity	Molecular function	16520378
VIM	7431	vimentin	identical protein binding	Molecular function	15383276
CDK1	983	cyclin-dependent kinase 1	mitotic nuclear division	Biological process	-
ZNF214	7761	zinc finger protein 214	transcription, DNA-templated	Biological process	-
BDKRB2	624	bradykinin receptor B2	negative regulation of peptidyl-serine phosphorylation	Biological process	-
GTF2IRD1	9569	GTF2I repeat domain containing 1	regulation of transcription from RNA polymerase II promoter	Biological process	9774679
AKT1	207	v-akt murine thymoma viral oncogene homolog 1	mitochondrion	Cellular component	-
PSIP1	11168	PC4 and SFRS1 interacting protein 1	nucleoplasm	Cellular component	-
TGFB1	7040	transforming growth factor, beta 1	negative regulation of cell proliferation	Biological process	15334054
POLE	5426	polymerase (DNA directed), epsilon, catalytic subunit	DNA-directed DNA polymerase activity	Molecular function	16762037
SMC4	10051	structural maintenance of chromosomes 4	condensin complex	Cellular component	11850403
BTN2A1	11120	butyrophilin, subfamily 2, member A1	molecular_function	Molecular function	-
SYTL2	54843	synaptotagmin-like 2	negative regulation of phosphatase activity	Biological process	19389623
DNMT3B	1789	DNA (cytosine-5-)-methyltransferase 3 beta	cytoplasm	Cellular component	-
TRIM32	22954	tripartite motif containing 32	protein binding	Molecular function	16189514
PRKACB	5567	protein kinase, cAMP-dependent, catalytic, beta	cAMP-dependent protein kinase activity	Molecular function	12420224
ZP3	7784	zona pellucida glycoprotein 3 (sperm receptor)	positive regulation of protein kinase B signaling	Biological process	-
FAM129B	64855	family with sequence similarity 129, member B	adherens junction	Cellular component	21148485
HLA-DPB1	3115	major histocompatibility complex, class II, DP beta 1	peptide antigen binding	Molecular function	20356827
ITGA4	3676	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	extracellular matrix organization	Biological process	-
ESRP2	80004	epithelial splicing regulatory protein 2	nucleus	Cellular component	19285943
OTX2	5015	orthodenticle homeobox 2	regulation of smoothened signaling pathway	Biological process	15705863
STAT5A	6776	signal transducer and activator of transcription 5A	luteinization	Biological process	-
SRF	6722	serum response factor (c-fos serum response element-binding transcription factor)	hematopoietic stem cell differentiation	Biological process	-
HMGCL	3155	3-hydroxymethyl-3-methylglutaryl-CoA lyase	response to starvation	Biological process	-
ZDHHC5	25921	zinc finger, DHHC-type containing 5	palmitoyltransferase activity	Molecular function	22325201
KLK7	5650	kallikrein-related peptidase 7	serine-type peptidase activity	Molecular function	8034709
ATP6V1B1	525	ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1	calcium ion homeostasis	Biological process	19478356
C1QTNF9B-AS1	542767	C1QTNF9B antisense RNA 1	protein binding	Molecular function	25416956
MAP3K7	6885	mitogen-activated protein kinase kinase kinase 7	angiogenesis	Biological process	-
UBIAD1	29914	UbiA prenyltransferase domain containing 1	integral component of Golgi membrane	Cellular component	23374346
ABCG1	9619	ATP-binding cassette, sub-family G (WHITE), member 1	ADP binding	Molecular function	16702602
GXYLT1	283464	glucoside xylosyltransferase 1	small molecule metabolic process	Biological process	-
MRPS12	6183	mitochondrial ribosomal protein S12	mitochondrial inner membrane	Cellular component	-
C21orf62	56245	chromosome 21 open reading frame 62	biological_process	Biological process	-
SEC22A	26984	SEC22 vesicle trafficking protein homolog A (S. cerevisiae)	protein binding	Molecular function	21516116
UQCRFS1P1	100128525	ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 pseudogene 1	2 iron, 2 sulfur cluster binding	Molecular function	-
ETNK2	55224	ethanolamine kinase 2	glycerophospholipid biosynthetic process	Biological process	-
SOAT2	8435	sterol O-acyltransferase 2	cholesterol homeostasis	Biological process	11401500
FCER1G	2207	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	cell surface	Cellular component	1535625
PLN	5350	phospholamban	protein binding	Molecular function	15598648
ACTG1	71	actin gamma 1	membrane organization	Biological process	-
GGT6	124975	gamma-glutamyltransferase 6	extracellular exosome	Cellular component	23376485
KHDRBS1	10657	KH domain containing, RNA binding, signal transduction associated 1	poly(U) RNA binding	Molecular function	21984414
IL6R	3570	interleukin 6 receptor	negative regulation of interleukin-8 production	Biological process	16034137
M1AP	130951	meiosis 1 associated protein	molecular_function	Molecular function	-
SMC5	23137	structural maintenance of chromosomes 5	cell division	Biological process	-
OR4C16	219428	olfactory receptor, family 4, subfamily C, member 16 (gene/pseudogene)	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
TMEM97	27346	transmembrane protein 97	integral component of membrane	Cellular component	-
BAIAP2	10458	BAI1-associated protein 2	response to bacterium	Biological process	19366662
CDK13	8621	cyclin-dependent kinase 13	cyclin K-CDK13 complex	Cellular component	22012619
TADA2A	6871	transcriptional adaptor 2A	PCAF complex	Cellular component	9674425
DHX30	22907	DEAH (Asp-Glu-Ala-His) box helicase 30	protein binding	Molecular function	-
CUBN	8029	cubilin (intrinsic factor-cobalamin receptor)	tissue homeostasis	Biological process	11994745
SEPSECS	51091	Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase	cytoplasm	Cellular component	-
PRRX1	5396	paired related homeobox 1	palate development	Biological process	-
HACD3	51495	3-hydroxyacyl-CoA dehydratase 3	Rho protein signal transduction	Biological process	-
HINFP	25988	histone H4 transcription factor	metal ion binding	Molecular function	-
LBR	3930	lamin B receptor	nuclear envelope	Cellular component	-
OR4B1	119765	olfactory receptor, family 4, subfamily B, member 1	G-protein coupled receptor signaling pathway	Biological process	-
DPH6	89978	diphthamine biosynthesis 6	ATP binding	Molecular function	-
ECT2	1894	epithelial cell transforming 2	cell-cell junction	Cellular component	15254234
VASP	7408	vasodilator-stimulated phosphoprotein	plasma membrane	Cellular component	-
OR4K15	81127	olfactory receptor, family 4, subfamily K, member 15	detection of chemical stimulus involved in sensory perception	Biological process	-
MAN1C1	57134	mannosidase, alpha, class 1C, member 1	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	Molecular function	10915796
CNP	1267	2',3'-cyclic nucleotide 3' phosphodiesterase	regulation of mitochondrial membrane permeability	Biological process	-
MECOM	2122	MDS1 and EVI1 complex locus	protein homodimerization activity	Molecular function	15897867
SHH	6469	sonic hedgehog	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
MTA1	9112	metastasis associated 1	nuclear envelope	Cellular component	24970816
SCT	6343	secretin	hormone activity	Molecular function	11060443
GARS	2617	glycyl-tRNA synthetase	axon	Cellular component	17035524
INHBA	3624	inhibin, beta A	peptide hormone binding	Molecular function	16198295
ANO1	55107	anoctamin 1, calcium activated chloride channel	protein binding	Molecular function	22178883
RAD23B	5887	RAD23 homolog B (S. cerevisiae)	damaged DNA binding	Molecular function	-
GEMIN6	79833	gem (nuclear organelle) associated protein 6	spliceosomal complex assembly	Biological process	-
SIX1	6495	SIX homeobox 1	protein binding	Molecular function	15141091
RNF112	7732	ring finger protein 112	positive regulation of glial cell differentiation	Biological process	-
UBE2N	7334	ubiquitin-conjugating enzyme E2N	positive regulation of DNA repair	Biological process	16129784
MEN1	4221	multiple endocrine neoplasia I	DNA repair	Biological process	12874027
OR51M1	390059	olfactory receptor, family 51, subfamily M, member 1	plasma membrane	Cellular component	-
CLDN18	51208	claudin 18	cell-cell junction organization	Biological process	-
TBX5	6910	T-box 5	morphogenesis of an epithelium	Biological process	-
PANK2	80025	pantothenate kinase 2	coenzyme A biosynthetic process	Biological process	-
PDP2	57546	pyruvate dehyrogenase phosphatase catalytic subunit 2	magnesium-dependent protein serine/threonine phosphatase activity	Molecular function	-
ARHGEF16	27237	Rho guanine nucleotide exchange factor (GEF) 16	positive regulation of apoptotic process	Biological process	-
ASPHD2	57168	aspartate beta-hydroxylase domain containing 2	peptidyl-amino acid modification	Biological process	-
SLC23A1	9963	solute carrier family 23 (ascorbic acid transporter), member 1	dehydroascorbic acid transport	Biological process	18247577
DICER1	23405	dicer 1, ribonuclease type III	helicase activity	Molecular function	-
ALDH1A2	8854	aldehyde dehydrogenase 1 family, member A2	cytoplasm	Cellular component	18495959
OSGEP	55644	O-sialoglycoprotein endopeptidase	metal ion binding	Molecular function	-
CXCR5	643	chemokine (C-X-C motif) receptor 5	protein binding	Molecular function	23773523
PARK2	5071	parkin RBR E3 ubiquitin protein ligase	positive regulation of tumor necrosis factor-mediated signaling pathway	Biological process	23453807
TNFSF4	7292	tumor necrosis factor (ligand) superfamily, member 4	positive regulation of alpha-beta T cell proliferation	Biological process	-
UHRF1	29128	ubiquitin-like with PHD and ring finger domains 1	regulation of gene expression, epigenetic	Biological process	-
SCOC	60592	short coiled-coil protein	endosome	Cellular component	22354037
HNRNPD	3184	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	nucleus	Cellular component	1433497
UBE2E1	7324	ubiquitin-conjugating enzyme E2E 1	ubiquitin-protein transferase activity	Molecular function	16307923
MINPP1	9562	multiple inositol-polyphosphate phosphatase 1	phosphohistidine phosphatase activity	Molecular function	10087200
POU6F2	11281	POU class 6 homeobox 2	central nervous system development	Biological process	8601806
STAG3	10734	stromal antigen 3	meiotic cohesin complex	Cellular component	21242291
TRPM4	54795	transient receptor potential cation channel, subfamily M, member 4	calcium channel activity	Molecular function	-
GABRA6	2559	gamma-aminobutyric acid (GABA) A receptor, alpha 6	transmembrane transport	Biological process	-
ANPEP	290	alanyl (membrane) aminopeptidase	endoplasmic reticulum-Golgi intermediate compartment	Cellular component	15308636
H3F3B	3021	H3 histone, family 3B (H3.3B)	nucleoplasm	Cellular component	-
IL12B	3593	interleukin 12B	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	Biological process	7903063
CHD2	1106	chromodomain helicase DNA binding protein 2	DNA duplex unwinding	Biological process	9326634
LOXL2	4017	lysyl oxidase-like 2	oxidation-reduction process	Biological process	22483618
DRD5	1816	dopamine receptor D5	cellular calcium ion homeostasis	Biological process	9457173
BAK1	578	BCL2-antagonist/killer 1	activation of signaling protein activity involved in unfolded protein response	Biological process	22013210
IRG1	730249	immunoresponsive 1 homolog (mouse)	positive regulation of reactive oxygen species metabolic process	Biological process	-
COL8A1	1295	collagen, type VIII, alpha 1	endoplasmic reticulum lumen	Cellular component	-
DDX23	9416	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23	nucleus	Cellular component	-
MLLT4	4301	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	signal transduction	Biological process	-
MIXL1	83881	Mix paired-like homeobox	RNA polymerase II distal enhancer sequence-specific DNA binding	Molecular function	-
DDX6	1656	DEAD (Asp-Glu-Ala-Asp) box helicase 6	ATP binding	Molecular function	-
PPP1R12A	4659	protein phosphatase 1, regulatory subunit 12A	negative regulation of catalytic activity	Biological process	19245366
WISP2	8839	WNT1 inducible signaling pathway protein 2	extracellular exosome	Cellular component	23376485
FAM90A9P	441327	putative protein FAM90A9	zinc ion binding	Molecular function	-
ESR1	2099	estrogen receptor 1	beta-catenin binding	Molecular function	15304487
S100A6	6277	S100 calcium binding protein A6	nuclear envelope	Cellular component	12577318
CBX2	84733	chromobox homolog 2	negative regulation of transcription from RNA polymerase II promoter	Biological process	21282530
RAB27A	5873	RAB27A, member RAS oncogene family	exosomal secretion	Biological process	23092844
ZNRD1	30834	zinc ribbon domain containing 1	transcription from RNA polymerase I promoter	Biological process	-
GABPA	2551	GA binding protein transcription factor, alpha subunit 60kDa	nucleus	Cellular component	9857059
EVC	2121	Ellis van Creveld protein	positive regulation of smoothened signaling pathway	Biological process	-
IRAK1	3654	interleukin-1 receptor-associated kinase 1	cellular response to heat	Biological process	-
DAB2IP	153090	DAB2 interacting protein	cellular protein catabolic process	Biological process	17389591
SOX6	55553	SRY (sex determining region Y)-box 6	positive regulation of chondrocyte differentiation	Biological process	21401405
C1QTNF5	114902	C1q and tumor necrosis factor related protein 5	extracellular exosome	Cellular component	23376485
ACSM1	116285	acyl-CoA synthetase medium-chain family member 1	butyrate-CoA ligase activity	Molecular function	11470804
FANCA	2175	Fanconi anemia, complementation group A	DNA repair	Biological process	-
ASNSD1	54529	asparagine synthetase domain containing 1	molecular_function	Molecular function	-
ACOT8	10005	acyl-CoA thioesterase 8	protein binding	Molecular function	22190034
RAB40C	57799	RAB40C, member RAS oncogene family	endosome membrane	Cellular component	-
UNC79	57578	unc-79 homolog (C. elegans)	ion transmembrane transport	Biological process	-
CLPX	10845	caseinolytic mitochondrial matrix peptidase chaperone subunit	mitochondrial matrix	Cellular component	10525407
ZPR1	8882	ZPR1 zinc finger	apoptotic process involved in development	Biological process	-
HLA-C	3107	major histocompatibility complex, class I, C	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent	Biological process	-
ANK2	287	ankyrin 2, neuronal	perinuclear region of cytoplasm	Cellular component	-
CCDC88C	440193	coiled-coil domain containing 88C	Wnt signaling pathway	Biological process	-
SETD2	29072	SET domain containing 2	morphogenesis of a branching structure	Biological process	-
SCN3B	55800	sodium channel, voltage gated, type III beta subunit	voltage-gated sodium channel activity involved in cardiac muscle cell action potential	Molecular function	21051419
CLDN4	1364	claudin 4	female pregnancy	Biological process	-
PPP1R14C	81706	protein phosphatase 1, regulatory (inhibitor) subunit 14C	cytoplasm	Cellular component	-
IGF2BP1	10642	insulin-like growth factor 2 mRNA binding protein 1	gene expression	Biological process	-
ARNTL2	56938	aryl hydrocarbon receptor nuclear translocator-like 2	E-box binding	Molecular function	12738229
DUOX1	53905	dual oxidase 1	heme binding	Molecular function	-
HCAR2	338442	hydroxycarboxylic acid receptor 2	positive regulation of neutrophil apoptotic process	Biological process	17932499
SQSTM1	8878	sequestosome 1	cytosol	Cellular component	8650207
NUCB2	4925	nucleobindin 2	DNA binding	Molecular function	-
ZNF609	23060	zinc finger protein 609	nucleus	Cellular component	-
CAPG	822	capping protein (actin filament), gelsolin-like	protein complex binding	Molecular function	18266911
SLC30A6	55676	solute carrier family 30 (zinc transporter), member 6	mitochondrion	Cellular component	-
TAF1	6872	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa	gene expression	Biological process	-
SYT1	6857	synaptotagmin I	protein C-terminus binding	Molecular function	-
DDX31	64794	DEAD (Asp-Glu-Ala-Asp) box polypeptide 31	intracellular membrane-bounded organelle	Cellular component	-
GNGT1	2792	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	cellular response to hypoxia	Biological process	-
NOP58	51602	NOP58 ribonucleoprotein	nucleolus	Cellular component	10925205
UST	10090	uronyl-2-sulfotransferase	protein sulfation	Biological process	10187838
RHBDD1	84236	rhomboid domain containing 1	protein binding	Molecular function	18953687
NUDT21	11051	nudix (nucleoside diphosphate linked moiety X)-type motif 21	gene expression	Biological process	-
PTF1A	256297	pancreas specific transcription factor, 1a	nucleus	Cellular component	-
RAD51C	5889	RAD51 paralog C	sister chromatid cohesion	Biological process	-
LCAT	3931	lecithin-cholesterol acyltransferase	extracellular exosome	Cellular component	23376485
RORB	6096	RAR-related orphan receptor B	regulation of circadian rhythm	Biological process	-
MNT	4335	MAX network transcriptional repressor	nucleoplasm	Cellular component	-
PRDX6	9588	peroxiredoxin 6	cytoplasm	Cellular component	19188445
DLK2	65989	delta-like 2 homolog (Drosophila)	extracellular exosome	Cellular component	23376485
SPTBN1	6711	spectrin, beta, non-erythrocytic 1	protein complex	Cellular component	-
ADIPOQ	9370	adiponectin, C1Q and collagen domain containing	negative regulation of tumor necrosis factor-mediated signaling pathway	Biological process	10604883
PLB1	151056	phospholipase B1	small molecule metabolic process	Biological process	-
CRABP2	1382	cellular retinoic acid binding protein 2	embryonic forelimb morphogenesis	Biological process	-
UBXN4	23190	UBX domain protein 4	response to unfolded protein	Biological process	-
PLCB2	5330	phospholipase C, beta 2	synaptic transmission	Biological process	-
ITGB7	3695	integrin, beta 7	cell-matrix adhesion involved in ameboidal cell migration	Biological process	23986478
PPARD	5467	peroxisome proliferator-activated receptor delta	nucleoplasm	Cellular component	-
PTEN	5728	phosphatase and tensin homolog	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity	Molecular function	-
RASL10A	10633	RAS-like, family 10, member A	nucleolus	Cellular component	-
FGFBP1	9982	fibroblast growth factor binding protein 1	fibroblast growth factor binding	Molecular function	-
MTFR2	113115	mitochondrial fission regulator 2	protein binding	Molecular function	25416956
CYGB	114757	cytoglobin	nitric oxide dioxygenase activity	Molecular function	-
SPATA31C2	645961	SPATA31 subfamily C, member 2	cell differentiation	Biological process	-
HS6ST2	90161	heparan sulfate 6-O-sulfotransferase 2	Golgi membrane	Cellular component	-
FGF4	2249	fibroblast growth factor 4	stem cell maintenance	Biological process	-
CASP10	843	caspase 10, apoptosis-related cysteine peptidase	activation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	-
HOMER2	9455	homer scaffolding protein 2	regulation of G-protein coupled receptor protein signaling pathway	Biological process	-
ADAM15	8751	ADAM metallopeptidase domain 15	proteolysis	Biological process	-
GEMIN8	54960	gem (nuclear organelle) associated protein 8	nucleoplasm	Cellular component	-
RTP1	132112	receptor (chemosensory) transporter protein 1	integral component of membrane	Cellular component	-
NPFFR2	10886	neuropeptide FF receptor 2	regulation of adenylate cyclase activity	Biological process	-
CCDC25	55246	coiled-coil domain containing 25	protein binding	Molecular function	25416956
RPS27A	6233	ribosomal protein S27a	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	Biological process	-
MLXIPL	51085	MLX interacting protein-like	cytoplasm	Cellular component	11230181
ADRA1A	148	adrenoceptor alpha 1A	negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure	Biological process	-
PIGV	55650	phosphatidylinositol glycan anchor biosynthesis, class V	cellular protein metabolic process	Biological process	-
PRKAA1	5562	protein kinase, AMP-activated, alpha 1 catalytic subunit	glucose metabolic process	Biological process	-
CSPG4	1464	chondroitin sulfate proteoglycan 4	intracellular signal transduction	Biological process	10587647
RAB24	53917	RAB24, member RAS oncogene family	Rab protein signal transduction	Biological process	-
LSM14A	26065	LSM14A, SCD6 homolog A (S. cerevisiae)	cytoplasmic mRNA processing body	Cellular component	16484376
CCRN4L	25819	CCR4 carbon catabolite repression 4-like (S. cerevisiae)	cytoplasmic mRNA processing body assembly	Biological process	-
YWHAB	7529	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta	viral process	Biological process	-
CBWD2	150472	COBW domain containing 2	ATP binding	Molecular function	-
ACKR4	51554	atypical chemokine receptor 4	receptor-mediated endocytosis	Biological process	-
NDUFV3	4731	NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa	mitochondrial electron transport, NADH to ubiquinone	Biological process	9878551
ACVRL1	94	activin A receptor type II-like 1	transforming growth factor beta binding	Molecular function	8242742
MLLT10	8028	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10	DNA binding	Molecular function	-
IL26	55801	interleukin 26	cell-cell signaling	Biological process	10729163
BRMS1	25855	breast cancer metastasis suppressor 1	chromatin organization	Biological process	-
DLG4	1742	discs, large homolog 4 (Drosophila)	endoplasmic reticulum	Cellular component	-
GRB2	2885	growth factor receptor-bound protein 2	platelet activation	Biological process	-
TIAM2	26230	T-cell lymphoma invasion and metastasis 2	cellular lipid metabolic process	Biological process	-
NINJ2	4815	ninjurin 2	nervous system development	Biological process	10627596
HIST1H3I	8354	histone cluster 1, H3i	nucleus	Cellular component	21630459
NEDD4L	23327	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase	positive regulation of caveolin-mediated endocytosis	Biological process	22879586
TLR7	51284	toll-like receptor 7	positive regulation of chemokine production	Biological process	19740627
IFNA8	3445	interferon, alpha 8	defense response to virus	Biological process	-
GTF2H2	2966	general transcription factor IIH, polypeptide 2, 44kDa	response to UV	Biological process	8194529
SOX4	6659	SRY (sex determining region Y)-box 4	negative regulation of protein export from nucleus	Biological process	19234109
ZIC3	7547	Zic family member 3	heart looping	Biological process	9354794
TTLL11	158135	tubulin tyrosine ligase-like family member 11	ligase activity	Molecular function	-
LAPTM5	7805	lysosomal protein transmembrane 5	transport	Biological process	-
CUTC	51076	cutC copper transporter	cytoplasm	Cellular component	-
NUP188	23511	nucleoporin 188kDa	mitotic cell cycle	Biological process	-
APOA2	336	apolipoprotein A-II	endoplasmic reticulum lumen	Cellular component	-
SNX33	257364	sorting nexin 33	protein import	Biological process	18353773
IL6	3569	interleukin 6	positive regulation of B cell activation	Biological process	3491322
EFNA1	1942	ephrin-A1	positive regulation of peptidyl-tyrosine phosphorylation	Biological process	10655584
ABCG1	9619	ATP-binding cassette, sub-family G (WHITE), member 1	response to high density lipoprotein particle	Biological process	-
USF1	7391	upstream transcription factor 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	18234320
ASS1	445	argininosuccinate synthase 1	liver development	Biological process	-
NOTCH2	4853	notch 2	negative regulation of apoptotic process	Biological process	12531696
SLC44A5	204962	solute carrier family 44, member 5	transmembrane transport	Biological process	-
SNX4	8723	sorting nexin 4	membrane	Cellular component	9819414
HES1	3280	hes family bHLH transcription factor 1	sequence-specific DNA binding	Molecular function	-
WDR12	55759	WD repeat domain 12	protein binding	Molecular function	16043514
FBXO28	23219	F-box protein 28	protein binding	Molecular function	21516116
CPNE3	8895	copine III	protein serine/threonine kinase activity	Molecular function	11041869
NLGN2	57555	neuroligin 2	postsynaptic membrane	Cellular component	10892652
FOXA2	3170	forkhead box A2	nucleus	Cellular component	20160041
PRKAA1	5562	protein kinase, AMP-activated, alpha 1 catalytic subunit	response to UV	Biological process	-
HSPA8	3312	heat shock 70kDa protein 8	protein refolding	Biological process	21231916
SARNP	84324	SAP domain containing ribonucleoprotein	protein binding	Molecular function	16189514
MEIS1	4211	Meis homeobox 1	megakaryocyte development	Biological process	-
GSS	2937	glutathione synthetase	response to amino acid	Biological process	-
CBLB	868	Cbl proto-oncogene B, E3 ubiquitin protein ligase	nucleoplasm	Cellular component	-
NT5DC3	51559	5'-nucleotidase domain containing 3	5'-nucleotidase activity	Molecular function	-
ABL1	25	ABL proto-oncogene 1, non-receptor tyrosine kinase	regulation of cell motility	Biological process	20841568
SOX9	6662	SRY (sex determining region Y)-box 9	cellular response to mechanical stimulus	Biological process	21512138
WRNIP1	56897	Werner helicase interacting protein 1	ATPase activity	Molecular function	15670210
SLC7A9	11136	solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9	blood coagulation	Biological process	-
APLP1	333	amyloid beta (A4) precursor-like protein 1	plasma membrane	Cellular component	16531006
ANGPT4	51378	angiopoietin 4	endothelial cell proliferation	Biological process	10025962
HNRNPM	4670	heterogeneous nuclear ribonucleoprotein M	alternative mRNA splicing, via spliceosome	Biological process	19874820
POLR3G	10622	polymerase (RNA) III (DNA directed) polypeptide G (32kD)	RNA polymerase III activity	Molecular function	-
GALC	2581	galactosylceramidase	small molecule metabolic process	Biological process	-
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	positive regulation of epithelial to mesenchymal transition	Biological process	23983127
RPEL1	729020	ribulose-5-phosphate-3-epimerase-like 1	carbohydrate metabolic process	Biological process	-
RNF7	9616	ring finger protein 7	Cul4-RING E3 ubiquitin ligase complex	Cellular component	-
MYOD1	4654	myogenic differentiation 1	cellular response to starvation	Biological process	-
TCF7L2	6934	transcription factor 7-like 2 (T-cell specific, HMG-box)	negative regulation of fibroblast growth factor receptor signaling pathway	Biological process	-
TGFB2	7042	transforming growth factor, beta 2	salivary gland morphogenesis	Biological process	18080134
NFE2L1	4779	nuclear factor, erythroid 2-like 1	transcription cofactor activity	Molecular function	9826775
MYL4	4635	myosin, light chain 4, alkali; atrial, embryonic	positive regulation of ATPase activity	Biological process	9738905
EGFR	1956	epidermal growth factor receptor	single organismal cell-cell adhesion	Biological process	12435727
FOXG1	2290	forkhead box G1	brain development	Biological process	7599184
RBM34	23029	RNA binding motif protein 34	nucleus	Cellular component	-
LIPC	3990	lipase, hepatic	very-low-density lipoprotein particle remodeling	Biological process	8640403
LRP6	4040	low density lipoprotein receptor-related protein 6	cerebral cortex cell migration	Biological process	-
TXK	7294	TXK tyrosine kinase	B cell receptor signaling pathway	Biological process	-
RPL13	6137	ribosomal protein L13	protein binding	Molecular function	17474147
EPN2	22905	epsin 2	in utero embryonic development	Biological process	-
GSTM2	2946	glutathione S-transferase mu 2 (muscle)	glutathione metabolic process	Biological process	16549767
PNPLA2	57104	patatin-like phospholipase domain containing 2	negative regulation of sequestering of triglyceride	Biological process	16679289
MACF1	23499	microtubule-actin crosslinking factor 1	microtubule	Cellular component	16076900
ZCCHC9	84240	zinc finger, CCHC domain containing 9	zinc ion binding	Molecular function	-
LEP	3952	leptin	negative regulation of apoptotic process	Biological process	-
HS3ST2	9956	heparan sulfate (glucosamine) 3-O-sulfotransferase 2	Golgi membrane	Cellular component	-
TTN	7273	titin	striated muscle thin filament	Cellular component	11717165
ACADL	33	acyl-CoA dehydrogenase, long chain	cellular lipid metabolic process	Biological process	-
LRP5	4041	low density lipoprotein receptor-related protein 5	retina morphogenesis in camera-type eye	Biological process	15346351
SERPINE1	5054	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	extracellular matrix	Cellular component	1632457
PGM2L1	283209	phosphoglucomutase 2-like 1	cytosol	Cellular component	-
POLR2J	5439	polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa	transcription from RNA polymerase II promoter	Biological process	-
POLDIP3	84271	polymerase (DNA-directed), delta interacting protein 3	protein binding	Molecular function	18423201
RAB31	11031	RAB31, member RAS oncogene family	trans-Golgi network membrane	Cellular component	17678623
PHF6	84295	PHD finger protein 6	enzyme binding	Molecular function	22720776
HOXA7	3204	homeobox A7	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	11435435
RNPEP	6051	arginyl aminopeptidase (aminopeptidase B)	extracellular space	Cellular component	-
CSF1	1435	colony stimulating factor 1 (macrophage)	regulation of macrophage derived foam cell differentiation	Biological process	18566389
PER3	8863	period circadian clock 3	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
PPP4C	5531	protein phosphatase 4, catalytic subunit	dephosphorylation	Biological process	9837938
SRSF5	6430	serine/arginine-rich splicing factor 5	transcription from RNA polymerase II promoter	Biological process	-
C5AR1	728	complement component 5a receptor 1	cell proliferation in hindbrain	Biological process	-
TTR	7276	transthyretin	identical protein binding	Molecular function	19861125
SP1	6667	Sp1 transcription factor	enhancer binding	Molecular function	-
CHRNB2	1141	cholinergic receptor, nicotinic, beta 2 (neuronal)	lateral geniculate nucleus development	Biological process	-
IGSF8	93185	immunoglobulin superfamily, member 8	extracellular exosome	Cellular component	19199708
CHRNB2	1141	cholinergic receptor, nicotinic, beta 2 (neuronal)	behavioral response to nicotine	Biological process	17559419
RPS6KA6	27330	ribosomal protein S6 kinase, 90kDa, polypeptide 6	signal transduction	Biological process	10644430
DDR2	4921	discoidin domain receptor tyrosine kinase 2	peptidyl-tyrosine phosphorylation	Biological process	20004161
GLRX5	51218	glutaredoxin 5	mitochondrion	Cellular component	-
MFAP4	4239	microfibrillar-associated protein 4	regulation of collagen metabolic process	Biological process	22355679
NPTX1	4884	neuronal pentraxin I	synaptic transmission	Biological process	8884281
MRPL3	11222	mitochondrial ribosomal protein L3	mitochondrial large ribosomal subunit	Cellular component	20186120
RDH11	51109	retinol dehydrogenase 11 (all-trans/9-cis/11-cis)	photoreceptor inner segment	Cellular component	-
CYP2F1	1572	cytochrome P450, family 2, subfamily F, polypeptide 1	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	Molecular function	10383923
PNPT1	87178	polyribonucleotide nucleotidyltransferase 1	mRNA catabolic process	Biological process	12721301
LONRF2	164832	LON peptidase N-terminal domain and ring finger 2	proteolysis	Biological process	-
PSMD4	5710	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	antigen processing and presentation of exogenous peptide antigen via MHC class I	Biological process	-
RAMP1	10267	receptor (G protein-coupled) activity modifying protein 1	regulation of G-protein coupled receptor protein signaling pathway	Biological process	9620797
ZFP3	124961	ZFP3 zinc finger protein	DNA binding	Molecular function	-
CACNA1E	777	calcium channel, voltage-dependent, R type, alpha 1E subunit	transport	Biological process	8071363
GGTLC2	91227	gamma-glutamyltransferase light chain 2	anchored component of external side of plasma membrane	Cellular component	18357469
TIAM1	7074	T-cell lymphoma invasion and metastasis 1	Rac guanyl-nucleotide exchange factor activity	Molecular function	20361982
ELAC2	60528	elaC ribonuclease Z 2	mitochondrion	Cellular component	21593607
HPS5	11234	Hermansky-Pudlak syndrome 5	BLOC-2 complex	Cellular component	15030569
SPIN2B	474343	spindlin family, member 2B	gamete generation	Biological process	-
SMC5	23137	structural maintenance of chromosomes 5	nucleus	Cellular component	-
GPX3	2878	glutathione peroxidase 3	glutathione peroxidase activity	Molecular function	1897960
CITED2	10370	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	transcription corepressor activity	Molecular function	17906695
B9D1	27077	B9 protein domain 1	cilium assembly	Biological process	-
CACNA1I	8911	calcium channel, voltage-dependent, T type, alpha 1I subunit	calcium ion transmembrane transport	Biological process	-
FKBP1B	2281	FK506 binding protein 1B, 12.6 kDa	positive regulation of axon regeneration	Biological process	-
SEZ6	124925	seizure related 6 homolog (mouse)	cerebellar Purkinje cell layer development	Biological process	-
DGKD	8527	diacylglycerol kinase, delta 130kDa	platelet activation	Biological process	-
CD79B	974	CD79b molecule, immunoglobulin-associated beta	Golgi apparatus	Cellular component	-
RALB	5899	v-ral simian leukemia viral oncogene homolog B	apoptotic process	Biological process	-
CADPS2	93664	Ca++-dependent secretion activator 2	metal ion binding	Molecular function	-
HDDC2	51020	HD domain containing 2	protein binding	Molecular function	22190034
KLHL20	27252	kelch-like family member 20	axon	Cellular component	-
SQSTM1	8878	sequestosome 1	activation of mitophagy in response to mitochondrial depolarization	Biological process	22020285
PSME1	5720	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)	innate immune response	Biological process	-
TRIM16	10626	tripartite motif containing 16	protein binding	Molecular function	16575408
AGL	178	amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase	nucleoplasm	Cellular component	-
PRAME	23532	preferentially expressed antigen in melanoma	positive regulation of cell proliferation	Biological process	16179254
ARHGAP23	57636	Rho GTPase activating protein 23	extracellular exosome	Cellular component	19199708
EIF2AK3	9451	eukaryotic translation initiation factor 2-alpha kinase 3	identical protein binding	Molecular function	11907036
PYROXD1	79912	pyridine nucleotide-disulphide oxidoreductase domain 1	oxidoreductase activity	Molecular function	-
USH1C	10083	Usher syndrome 1C (autosomal recessive, severe)	plasma membrane	Cellular component	-
OR6V1	346517	olfactory receptor, family 6, subfamily V, member 1	G-protein coupled receptor signaling pathway	Biological process	-
CWC15	51503	CWC15 spliceosome-associated protein	protein binding	Molecular function	20176811
CLIC1	1192	chloride intracellular channel 1	positive regulation of osteoblast differentiation	Biological process	-
PCSK9	255738	proprotein convertase subtilisin/kexin type 9	negative regulation of low-density lipoprotein particle clearance	Biological process	17328821
TOM1	10043	target of myb1 (chicken)	cytoplasm	Cellular component	16412388
ATM	472	ATM serine/threonine kinase	phosphatidylinositol-3-phosphate biosynthetic process	Biological process	11375976
FGD4	121512	FYVE, RhoGEF and PH domain containing 4	cytoskeleton organization	Biological process	-
STX5	6811	syntaxin 5	protein N-terminus binding	Molecular function	19536132
ZMAT4	79698	zinc finger, matrin-type 4	zinc ion binding	Molecular function	-
ABT1	29777	activator of basal transcription 1	spinal cord motor neuron differentiation	Biological process	-
ASAP1	50807	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	cytosol	Cellular component	-
PIAS3	10401	protein inhibitor of activated STAT, 3	cytoplasm	Cellular component	-
RPS13	6207	ribosomal protein S13	protein binding	Molecular function	12054647
SPX	80763	spexin hormone	type 2 galanin receptor binding	Molecular function	24517231
OR10R2	343406	olfactory receptor, family 10, subfamily R, member 2	G-protein coupled receptor activity	Molecular function	-
CANX	821	calnexin	dendritic spine	Cellular component	-
XAB2	56949	XPA binding protein 2	transcription, DNA-templated	Biological process	10944529
GPIHBP1	338328	glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1	positive regulation of chylomicron remnant clearance	Biological process	-
RPGRIP1L	23322	RPGRIP1-like	centrosome	Cellular component	17558409
MGST1	4257	microsomal glutathione S-transferase 1	protein binding	Molecular function	20195357
TRIP12	9320	thyroid hormone receptor interactor 12	embryo development	Biological process	-
COPS6	10980	COP9 signalosome subunit 6	extracellular exosome	Cellular component	23376485
TTC37	9652	tetratricopeptide repeat domain 37	cytoplasm	Cellular component	-
ACOX3	8310	acyl-CoA oxidase 3, pristanoyl	peroxisome	Cellular component	8993592
TRIM49	57093	tripartite motif containing 49	intracellular	Cellular component	-
UBE2G2	7327	ubiquitin-conjugating enzyme E2G 2	identical protein binding	Molecular function	-
BMP2	650	bone morphogenetic protein 2	growth	Biological process	-
MRPL11	65003	mitochondrial ribosomal protein L11	poly(A) RNA binding	Molecular function	22658674
B2M	567	beta-2-microglobulin	endoplasmic reticulum lumen	Cellular component	-
P2RY11	5032	purinergic receptor P2Y, G-protein coupled, 11	G-protein coupled purinergic nucleotide receptor signaling pathway	Biological process	-
NR0B2	8431	nuclear receptor subfamily 0, group B, member 2	steroid hormone receptor activity	Molecular function	-
AREG	374	amphiregulin	cytokine activity	Molecular function	-
RHOT2	89941	ras homolog family member T2	regulation of small GTPase mediated signal transduction	Biological process	-
KRT78	196374	keratin 78, type II	keratin filament	Cellular component	-
SULT1A2	6799	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2	sulfotransferase activity	Molecular function	9119390
VIMP	55829	VCP-interacting membrane selenoprotein	response to glucose	Biological process	12031974
SZT2	23334	seizure threshold 2 homolog (mouse)	regulation of superoxide dismutase activity	Biological process	20045724
RAMP1	10267	receptor (G protein-coupled) activity modifying protein 1	calcitonin receptor activity	Molecular function	9620797
MYH13	8735	myosin, heavy chain 13, skeletal muscle	microfilament motor activity	Molecular function	10388558
TICAM2	353376	toll-like receptor adaptor molecule 2	positive regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	12761501
CMTM3	123920	CKLF-like MARVEL transmembrane domain containing 3	cytokine activity	Molecular function	-
GSC	145258	goosecoid homeobox	forebrain development	Biological process	-
CWC22	57703	CWC22 spliceosome-associated protein	cytoplasm	Cellular component	-
SYS1	90196	Sys1 golgi trafficking protein	Golgi to plasma membrane protein transport	Biological process	-
ALMS1	7840	Alstrom syndrome protein 1	mitotic cell cycle	Biological process	-
PTPRG	5793	protein tyrosine phosphatase, receptor type, G	extracellular exosome	Cellular component	23376485
ACO1	48	aconitase 1, soluble	cytosol	Cellular component	16527810
GUCA1B	2979	guanylate cyclase activator 1B (retina)	photoreceptor inner segment	Cellular component	-
ZNF300	91975	zinc finger protein 300	metal ion binding	Molecular function	-
GPR135	64582	G protein-coupled receptor 135	integral component of membrane	Cellular component	-
CALM2	805	calmodulin 2 (phosphorylase kinase, delta)	nitric-oxide synthase binding	Molecular function	-
NQO2	4835	NAD(P)H dehydrogenase, quinone 2	protein binding	Molecular function	25416956
PSMA2	5683	proteasome (prosome, macropain) subunit, alpha type, 2	G1/S transition of mitotic cell cycle	Biological process	-
NOTCH2	4853	notch 2	stem cell maintenance	Biological process	11306509
CHRNA4	1137	cholinergic receptor, nicotinic, alpha 4 (neuronal)	synaptic transmission, cholinergic	Biological process	-
STK17A	9263	serine/threonine kinase 17a	intracellular signal transduction	Biological process	9786912
UBXN2B	137886	UBX domain protein 2B	protein binding	Molecular function	25416956
PARL	55486	presenilin associated, rhomboid-like	regulation of reactive oxygen species metabolic process	Biological process	21138942
PCBD1	5092	pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha	oxidation-reduction process	Biological process	-
RASA4B	100271927	RAS p21 protein activator 4B	intracellular signal transduction	Biological process	-
KCNV1	27012	potassium channel, voltage gated modifier subfamily V, member 1	potassium ion transport	Biological process	8670833
RP1	6101	retinitis pigmentosa 1 (autosomal dominant)	protein binding	Molecular function	21148103
TAOK2	9344	TAO kinase 2	cell migration	Biological process	10660600
B3GNT2	10678	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	keratan sulfate metabolic process	Biological process	-
DIP2B	57609	DIP2 disco-interacting protein 2 homolog B (Drosophila)	cytoplasm	Cellular component	15531550
IFNLR1	163702	interferon, lambda receptor 1	response to type III interferon	Biological process	-
CD80	941	CD80 molecule	positive regulation of T-helper 1 cell differentiation	Biological process	9915850
ARHGDIB	397	Rho GDP dissociation inhibitor (GDI) beta	GTPase activity	Molecular function	24554735
BRD4	23476	bromodomain containing 4	positive regulation of transcription elongation from RNA polymerase II promoter	Biological process	18039861
ATP6V0A1	535	ATPase, H+ transporting, lysosomal V0 subunit a1	phagocytic vesicle membrane	Cellular component	-
NACC2	138151	NACC family member 2, BEN and BTB (POZ) domain containing	negative regulation of transcription, DNA-templated	Biological process	-
SOS2	6655	son of sevenless homolog 2 (Drosophila)	apoptotic signaling pathway	Biological process	-
CIAO1	9391	cytosolic iron-sulfur assembly component 1	iron-sulfur cluster assembly	Biological process	17937914
THBS1	7057	thrombospondin 1	platelet activation	Biological process	-
NANOG	79923	Nanog homeobox	nucleolus	Cellular component	20458727
ROCK1	6093	Rho-associated, coiled-coil containing protein kinase 1	protein binding	Molecular function	10652353
RITA1	84934	RBPJ interacting and tubulin associated 1	tubulin binding	Molecular function	21102556
MAEA	10296	macrophage erythroblast attacher	nuclear matrix	Cellular component	16510120
CLCA4	22802	chloride channel accessory 4	chloride transport	Biological process	10437792
DPF2	5977	D4, zinc and double PHD fingers family 2	protein binding	Molecular function	25416956
TRBC1	28639	T cell receptor beta constant 1	membrane	Cellular component	6336315
ACP5	54	acid phosphatase 5, tartrate resistant	dephosphorylation	Biological process	-
ARHGAP12	94134	Rho GTPase activating protein 12	positive regulation of GTPase activity	Biological process	-
FBXW4	6468	F-box and WD repeat domain containing 4	embryonic limb morphogenesis	Biological process	10405324
TRIM37	4591	tripartite motif containing 37	transcription, DNA-templated	Biological process	-
SOHLH1	402381	spermatogenesis and oogenesis specific basic helix-loop-helix 1	protein dimerization activity	Molecular function	-
TNFSF4	7292	tumor necrosis factor (ligand) superfamily, member 4	response to virus	Biological process	-
BMPR2	659	bone morphogenetic protein receptor, type II (serine/threonine kinase)	anterior/posterior pattern specification	Biological process	-
EFNB3	1949	ephrin-B3	adult walking behavior	Biological process	-
LOX	4015	lysyl oxidase	proteinaceous extracellular matrix	Cellular component	-
VANGL2	57216	VANGL planar cell polarity protein 2	convergent extension involved in neural plate elongation	Biological process	-
PDCD6	10016	programmed cell death 6	negative regulation of TOR signaling	Biological process	21893193
MAPK7	5598	mitogen-activated protein kinase 7	negative regulation of endothelial cell apoptotic process	Biological process	23043106
CD40	958	CD40 molecule, TNF receptor superfamily member 5	regulation of immune response	Biological process	-
C5	727	complement component 5	negative regulation of macrophage chemotaxis	Biological process	14566334
RAB40C	57799	RAB40C, member RAS oncogene family	Rab protein signal transduction	Biological process	-
RASEF	158158	RAS and EF-hand domain containing	intracellular protein transport	Biological process	-
OR5M10	390167	olfactory receptor, family 5, subfamily M, member 10	plasma membrane	Cellular component	-
MYOT	9499	myotilin	sarcolemma	Cellular component	-
MAPKAPK3	7867	mitogen-activated protein kinase-activated protein kinase 3	cytoplasm	Cellular component	-
MRC1	4360	mannose receptor, C type 1	receptor activity	Molecular function	20035344
NT5C1B	93034	5'-nucleotidase, cytosolic IB	small molecule metabolic process	Biological process	-
DSP	1832	desmoplakin	extracellular exosome	Cellular component	19056867
NXF5	55998	nuclear RNA export factor 5	multicellular organismal development	Biological process	11566096
PRSS42	339906	protease, serine, 42	serine-type endopeptidase activity	Molecular function	-
SPTBN2	6712	spectrin, beta, non-erythrocytic 2	cell junction	Cellular component	-
SLC7A6OS	84138	solute carrier family 7, member 6 opposite strand	protein transport	Biological process	-
RHOXF1	158800	Rhox homeobox family, member 1	transcription, DNA-templated	Biological process	-
BIRC5	332	baculoviral IAP repeat containing 5	protein homodimerization activity	Molecular function	16291752
BRDT	676	bromodomain, testis-specific	regulation of RNA splicing	Biological process	-
SHH	6469	sonic hedgehog	spinal cord dorsal/ventral patterning	Biological process	-
ATP6V1B1	525	ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1	apical plasma membrane	Cellular component	16928804
MSGN1	343930	mesogenin 1	chromatin binding	Molecular function	-
AMH	268	anti-Mullerian hormone	gonadal mesoderm development	Biological process	-
ZNF485	220992	zinc finger protein 485	regulation of transcription, DNA-templated	Biological process	-
SERPINB6	5269	serpin peptidase inhibitor, clade B (ovalbumin), member 6	sensory perception of sound	Biological process	20451170
TOP2A	7153	topoisomerase (DNA) II alpha 170kDa	magnesium ion binding	Molecular function	22323612
PMS2	5395	PMS2 postmeiotic segregation increased 2 (S. cerevisiae)	somatic recombination of immunoglobulin gene segments	Biological process	-
STOM	2040	stomatin	cytoskeleton	Cellular component	1547348
SYT1	6857	synaptotagmin I	protein binding	Molecular function	11438518
GOLPH3	64083	golgi phosphoprotein 3 (coat-protein)	cell migration	Biological process	23500462
ANO3	63982	anoctamin 3	intracellular calcium activated chloride channel activity	Molecular function	21984732
TNFSF4	7292	tumor necrosis factor (ligand) superfamily, member 4	positive regulation of CD4-positive, alpha-beta T cell differentiation	Biological process	-
OR10J1	26476	olfactory receptor, family 10, subfamily J, member 1	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
TP63	8626	tumor protein p63	regulation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	-
GLP1R	2740	glucagon-like peptide 1 receptor	transmembrane signaling receptor activity	Molecular function	8405712
TRPM1	4308	transient receptor potential cation channel, subfamily M, member 1	calcium ion transmembrane transport	Biological process	-
FUT11	170384	fucosyltransferase 11 (alpha (1,3) fucosyltransferase)	protein glycosylation	Biological process	-
CRCP	27297	CGRP receptor component	protein binding	Molecular function	25416956
NAP1L6	645996	nucleosome assembly protein 1-like 6	nucleus	Cellular component	-
HIST1H1A	3024	histone cluster 1, H1a	protein binding	Molecular function	19895577
DMBT1	1755	deleted in malignant brain tumors 1	zymogen granule membrane	Cellular component	-
TOR1AIP2	163590	torsin A interacting protein 2	positive regulation of ATPase activity	Biological process	23569223
LEPROTL1	23484	leptin receptor overlapping transcript-like 1	integral component of membrane	Cellular component	-
HSPA1A	3303	heat shock 70kDa protein 1A	negative regulation of cell death	Biological process	21231916
ORM2	5005	orosomucoid 2	extracellular space	Cellular component	16502470
NBAS	51594	neuroblastoma amplified sequence	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Biological process	23828042
LBP	3929	lipopolysaccharide binding protein	cellular response to lipoteichoic acid	Biological process	12594207
ETS2	2114	v-ets avian erythroblastosis virus E26 oncogene homolog 2	nucleus	Cellular component	16780588
FARP2	9855	FERM, RhoGEF and pleckstrin domain protein 2	cytoplasm	Cellular component	12351724
ATP1A4	480	ATPase, Na+/K+ transporting, alpha 4 polypeptide	regulation of cellular pH	Biological process	12112599
DHFR	1719	dihydrofolate reductase	cellular_component	Cellular component	-
CPNE6	9362	copine VI (neuronal)	phospholipid metabolic process	Biological process	-
ZBTB2	57621	zinc finger and BTB domain containing 2	protein binding	Molecular function	25609694
MFF	56947	mitochondrial fission factor	mitochondrial outer membrane	Cellular component	21149567
LRAT	9227	lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)	transferase activity, transferring acyl groups	Molecular function	9920938
NDUFA4	4697	NDUFA4, mitochondrial complex associated	hydrogen ion transmembrane transport	Biological process	22902835
FOXI3	344167	forkhead box I3	sequence-specific DNA binding	Molecular function	-
DUSP19	142679	dual specificity phosphatase 19	protein binding	Molecular function	21516116
GDF3	9573	growth differentiation factor 3	in utero embryonic development	Biological process	-
PHLDA2	7262	pleckstrin homology-like domain, family A, member 2	regulation of cell migration	Biological process	-
CLCN6	1185	chloride channel, voltage-sensitive 6	signal transduction	Biological process	8543009
PTPRD	5789	protein tyrosine phosphatase, receptor type, D	peptidyl-tyrosine dephosphorylation	Biological process	7896816
NOMO3	408050	NODAL modulator 3	integral component of membrane	Cellular component	-
NF2	4771	neurofibromin 2 (merlin)	negative regulation of JAK-STAT cascade	Biological process	12444102
APOC4	346	apolipoprotein C-IV	positive regulation of sequestering of triglyceride	Biological process	18809223
SLC4A8	9498	solute carrier family 4, sodium bicarbonate cotransporter, member 8	transmembrane transport	Biological process	-
PRKACA	5566	protein kinase, cAMP-dependent, catalytic, alpha	intracellular signal transduction	Biological process	-
PITPNB	23760	phosphatidylinositol transfer protein, beta	endoplasmic reticulum membrane	Cellular component	-
PSMB7	5695	proteasome (prosome, macropain) subunit, beta type, 7	nucleoplasm	Cellular component	-
OR1E2	8388	olfactory receptor, family 1, subfamily E, member 2	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
FGFR2	2263	fibroblast growth factor receptor 2	epithelial cell differentiation	Biological process	-
GTF2IRD2	84163	GTF2I repeat domain containing 2	DNA binding	Molecular function	-
CTTN	2017	cortactin	intracellular protein transport	Biological process	17959782
KREMEN1	83999	kringle containing transmembrane protein 1	Wnt signaling pathway	Biological process	-
ATF4	468	activating transcription factor 4	ATF1-ATF4 transcription factor complex	Cellular component	12871976
EBF3	253738	early B-cell factor 3	transcription, DNA-templated	Biological process	-
GLRA2	2742	glycine receptor, alpha 2	ion transmembrane transport	Biological process	-
BRAF	673	B-Raf proto-oncogene, serine/threonine kinase	positive regulation of gene expression	Biological process	22065586
HES3	390992	hes family bHLH transcription factor 3	regulation of timing of neuron differentiation	Biological process	-
THOP1	7064	thimet oligopeptidase 1	proteolysis	Biological process	-
USF1	7391	upstream transcription factor 1	late viral transcription	Biological process	2249772
ITGB1BP2	26548	integrin beta 1 binding protein (melusin) 2	protein binding	Molecular function	25036637
KCNN1	3780	potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1	calcium-activated potassium channel activity	Molecular function	8781233
TAF1	6872	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa	p53 binding	Molecular function	15053879
PCSK9	255738	proprotein convertase subtilisin/kexin type 9	negative regulation of receptor recycling	Biological process	17452316
NDUFB4	4710	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa	cellular metabolic process	Biological process	-
PTCH1	5727	patched 1	renal system development	Biological process	17850284
LIN7B	64130	lin-7 homolog B (C. elegans)	L27 domain binding	Molecular function	-
EPS15L1	58513	epidermal growth factor receptor pathway substrate 15-like 1	protein binding	Molecular function	16159959
ONECUT2	9480	one cut homeobox 2	organ morphogenesis	Biological process	9915796
EDF1	8721	endothelial differentiation-related factor 1	histone acetyltransferase activity	Molecular function	12040021
VIM	7431	vimentin	peroxisome	Cellular component	17881773
POLR2A	5430	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	positive regulation of viral transcription	Biological process	-
RGS11	8786	regulator of G-protein signaling 11	cytoplasm	Cellular component	-
KIF2C	11004	kinesin family member 2C	blood coagulation	Biological process	-
RPS18	6222	ribosomal protein S18	viral process	Biological process	-
BEST1	7439	bestrophin 1	ion transmembrane transport	Biological process	-
IRAK1	3654	interleukin-1 receptor-associated kinase 1	JNK cascade	Biological process	-
HYAL3	8372	hyaluronoglucosaminidase 3	lysosome	Cellular component	16600643
TXK	7294	TXK tyrosine kinase	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	11859127
ATF6	22926	activating transcription factor 6	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	Biological process	22013210
MYF6	4618	myogenic factor 6 (herculin)	skeletal muscle cell differentiation	Biological process	-
IRF4	3662	interferon regulatory factor 4	nuclear nucleosome	Cellular component	-
SOCS2	8835	suppressor of cytokine signaling 2	cytoplasm	Cellular component	9727029
ANXA1	301	annexin A1	vesicle	Cellular component	19190083
GNA12	2768	guanine nucleotide binding protein (G protein) alpha 12	Rho protein signal transduction	Biological process	-
DHX9	1660	DEAH (Asp-Glu-Ala-His) box helicase 9	circadian rhythm	Biological process	-
PML	5371	promyelocytic leukemia	apoptotic process	Biological process	9583681
MEOX1	4222	mesenchyme homeobox 1	multicellular organismal development	Biological process	7987315
BCL10	8915	B-cell CLL/lymphoma 10	ubiquitin binding	Molecular function	15082780
ZNF385A	25946	zinc finger protein 385A	cytoplasm	Cellular component	-
FOXL2	668	forkhead box L2	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	16153597
CYP1A2	1544	cytochrome P450, family 1, subfamily A, polypeptide 2	iron ion binding	Molecular function	-
DPH1	1801	diphthamide biosynthesis 1	cytosol	Cellular component	-
THBS4	7060	thrombospondin 4	regulation of tissue remodeling	Biological process	-
PLCD3	113026	phospholipase C, delta 3	cleavage furrow	Cellular component	-
KCNE3	10008	potassium channel, voltage gated subfamily E regulatory beta subunit 3	potassium ion transmembrane transport	Biological process	-
MMP24	10893	matrix metallopeptidase 24 (membrane-inserted)	extracellular exosome	Cellular component	19056867
ASXL2	55252	additional sex combs like transcriptional regulator 2	adult heart development	Biological process	-
HCAR1	27198	hydroxycarboxylic acid receptor 1	G-protein coupled receptor activity	Molecular function	-
AMELX	265	amelogenin, X-linked	positive regulation of collagen biosynthetic process	Biological process	1734713
SNRPB	6628	small nuclear ribonucleoprotein polypeptides B and B1	ncRNA metabolic process	Biological process	-
HELT	391723	helt bHLH transcription factor	multicellular organism growth	Biological process	-
COL18A1	80781	collagen, type XVIII, alpha 1	cell adhesion	Biological process	-
SLC4A5	57835	solute carrier family 4 (sodium bicarbonate cotransporter), member 5	retina development in camera-type eye	Biological process	-
SYVN1	84447	synovial apoptosis inhibitor 1, synoviolin	cellular protein metabolic process	Biological process	-
CDC42	998	cell division cycle 42	hair follicle morphogenesis	Biological process	-
GRIN2B	2904	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	cell surface	Cellular component	-
VAV1	7409	vav 1 guanine nucleotide exchange factor	G-protein coupled receptor signaling pathway	Biological process	-
SRSF12	135295	serine/arginine-rich splicing factor 12	spliceosomal tri-snRNP complex assembly	Biological process	11684676
POLK	51426	polymerase (DNA directed) kappa	DNA replication	Biological process	-
PARP1	142	poly (ADP-ribose) polymerase 1	double-strand break repair	Biological process	23230272
ADCY3	109	adenylate cyclase 3	integral component of plasma membrane	Cellular component	9920776
STARD8	9754	StAR-related lipid transfer (START) domain containing 8	focal adhesion	Cellular component	-
SDC1	6382	syndecan 1	striated muscle cell development	Biological process	9566955
ANKH	56172	ANKH inorganic pyrophosphate transport regulator	outer membrane	Cellular component	11326272
PEX3	8504	peroxisomal biogenesis factor 3	cytosol	Cellular component	-
VNN1	8876	vanin 1	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	Biological process	15282320
MEN1	4221	multiple endocrine neoplasia I	protein complex	Cellular component	15199122
NME2	4831	NME/NM23 nucleoside diphosphate kinase 2	intracellular	Cellular component	-
BCLAF1	9774	BCL2-associated transcription factor 1	protein binding	Molecular function	10837489
LAT	27040	linker for activation of T cells	SH3/SH2 adaptor activity	Molecular function	9489702
ADAMTS12	81792	ADAM metallopeptidase with thrombospondin type 1 motif, 12	negative regulation of cellular response to vascular endothelial growth factor stimulus	Biological process	17895370
FAS	355	Fas cell surface death receptor	negative thymic T cell selection	Biological process	-
PTPRU	10076	protein tyrosine phosphatase, receptor type, U	protein binding	Molecular function	10397721
KRTAP9-4	85280	keratin associated protein 9-4	keratin filament	Cellular component	-
RAB6B	51560	RAB6B, member RAS oncogene family	Golgi apparatus	Cellular component	10893188
C14orf166	51637	chromosome 14 open reading frame 166	nucleus	Cellular component	24608264
PPP2R3B	28227	protein phosphatase 2, regulatory subunit B'', beta	calcium ion binding	Molecular function	-
LSM10	84967	LSM10, U7 small nuclear RNA associated	U7 snRNP	Cellular component	11574479
GRPR	2925	gastrin-releasing peptide receptor	regulation of cell proliferation	Biological process	-
IL2RG	3561	interleukin 2 receptor, gamma	plasma membrane	Cellular component	-
NPY	4852	neuropeptide Y	neuropeptide signaling pathway	Biological process	-
TTR	7276	transthyretin	phototransduction, visible light	Biological process	-
SCNN1G	6340	sodium channel, non voltage gated 1 gamma subunit	sodium channel complex	Cellular component	24124190
MINK1	50488	misshapen-like kinase 1	synaptic transmission	Biological process	-
ARHGAP4	393	Rho GTPase activating protein 4	protein binding	Molecular function	16417406
PRKCZ	5590	protein kinase C, zeta	membrane raft	Cellular component	-
ADM2	79924	adrenomedullin 2	angiogenesis	Biological process	20596610
SET	6418	SET nuclear proto-oncogene	regulation of protein phosphatase type 2A activity	Biological process	11555662
DMAP1	55929	DNA methyltransferase 1 associated protein 1	cytoplasm	Cellular component	15367675
NPAS1	4861	neuronal PAS domain protein 1	maternal behavior	Biological process	-
MAP3K5	4217	mitogen-activated protein kinase kinase kinase 5	intrinsic apoptotic signaling pathway in response to oxidative stress	Biological process	21771788
NKX2-5	1482	NK2 homeobox 5	cardiac muscle tissue morphogenesis	Biological process	11889119
ZBTB37	84614	zinc finger and BTB domain containing 37	DNA binding	Molecular function	-
IKZF1	10320	IKAROS family zinc finger 1 (Ikaros)	metal ion binding	Molecular function	-
RPS3	6188	ribosomal protein S3	mitochondrial inner membrane	Cellular component	-
HIST1H3I	8354	histone cluster 1, H3i	nucleoplasm	Cellular component	-
IL13	3596	interleukin 13	response to ethanol	Biological process	-
NIPBL	25836	Nipped-B homolog (Drosophila)	cognition	Biological process	15146186
WASH1	100287171	WAS protein family homolog 1	recycling endosome	Cellular component	-
RIPK2	8767	receptor-interacting serine-threonine kinase 2	MyD88-independent toll-like receptor signaling pathway	Biological process	-
STOX2	56977	storkhead box 2	molecular_function	Molecular function	-
USF1	7391	upstream transcription factor 1	protein heterodimerization activity	Molecular function	8576131
OR51I2	390064	olfactory receptor, family 51, subfamily I, member 2	plasma membrane	Cellular component	-
CCS	9973	copper chaperone for superoxide dismutase	removal of superoxide radicals	Biological process	-
CCDC103	388389	coiled-coil domain containing 103	cytoplasm	Cellular component	22581229
AATF	26574	apoptosis antagonizing transcription factor	focal adhesion	Cellular component	-
PER1	5187	period circadian clock 1	histone H3 deacetylation	Biological process	-
UMPS	7372	uridine monophosphate synthetase	'de novo' UMP biosynthetic process	Biological process	-
LEF1	51176	lymphoid enhancer-binding factor 1	positive regulation of cell-cell adhesion	Biological process	19653274
SNX6	58533	sorting nexin 6	endocytosis	Biological process	-
MAGEE1	57692	melanoma antigen family E1	postsynaptic membrane	Cellular component	14623885
TXN	7295	thioredoxin	negative regulation of hydrogen peroxide-induced cell death	Biological process	22492997
MAP3K13	9175	mitogen-activated protein kinase kinase kinase 13	identical protein binding	Molecular function	11163770
FGFR1OP	11116	FGFR1 oncogene partner	positive regulation of cell growth	Biological process	17888034
ATF1	466	activating transcription factor 1	innate immune response	Biological process	-
ATP6V0A1	535	ATPase, H+ transporting, lysosomal V0 subunit a1	insulin receptor signaling pathway	Biological process	-
ANXA13	312	annexin A13	phosphatidylglycerol binding	Molecular function	15813707
HOXD8	3234	homeobox D8	transcription, DNA-templated	Biological process	-
CADM1	23705	cell adhesion molecule 1	susceptibility to natural killer cell mediated cytotoxicity	Biological process	12826663
DKK1	22943	dickkopf WNT signaling pathway inhibitor 1	negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment	Biological process	20559569
GEMIN2	8487	gem (nuclear organelle) associated protein 2	RNA splicing	Biological process	9323129
HRC	3270	histidine rich calcium binding protein	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	Biological process	17526652
ZNF566	84924	zinc finger protein 566	transcription, DNA-templated	Biological process	-
IFT52	51098	intraflagellar transport 52	centriole	Cellular component	-
MTR	4548	5-methyltetrahydrofolate-homocysteine methyltransferase	xenobiotic metabolic process	Biological process	-
PTCH2	8643	patched 2	signal transduction	Biological process	11001584
ARHGDIB	397	Rho GDP dissociation inhibitor (GDI) beta	small GTPase mediated signal transduction	Biological process	-
SGPL1	8879	sphingosine-1-phosphate lyase 1	palate development	Biological process	-
MARVELD3	91862	MARVEL domain containing 3	cytoplasmic vesicle	Cellular component	20164257
GMPPA	29926	GDP-mannose pyrophosphorylase A	nucleotidyltransferase activity	Molecular function	-
FN1	2335	fibronectin 1	extracellular exosome	Cellular component	19056867
SLC22A9	114571	solute carrier family 22 (organic anion transporter), member 9	anion:anion antiporter activity	Molecular function	17393504
RFC5	5985	replication factor C (activator 1) 5, 36.5kDa	nucleotide-excision repair	Biological process	-
PPIA	5478	peptidylprolyl isomerase A (cyclophilin A)	peptide binding	Molecular function	-
F11	2160	coagulation factor XI	blood coagulation, intrinsic pathway	Biological process	-
CHD4	1108	chromodomain helicase DNA binding protein 4	nucleus	Cellular component	-
DBI	1622	diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)	perinuclear endoplasmic reticulum	Cellular component	21698759
AQP8	343	aquaporin 8	plasma membrane	Cellular component	-
CACNG8	59283	calcium channel, voltage-dependent, gamma subunit 8	calcium ion transport	Biological process	11170751
SPERT	220082	spermatid associated	protein binding	Molecular function	16189514
CASP8	841	caspase 8, apoptosis-related cysteine peptidase	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	-
ITGB1	3688	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	regulation of collagen catabolic process	Biological process	10455171
GRB10	2887	growth factor receptor-bound protein 10	negative regulation of glucose import	Biological process	15664450
DIS3	22894	DIS3 exosome endoribonuclease and 3'-5' exoribonuclease	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	Biological process	-
NFYC	4802	nuclear transcription factor Y, gamma	positive regulation of transcription, DNA-templated	Biological process	-
VPS4A	27183	vacuolar protein sorting 4 homolog A (S. cerevisiae)	negative regulation of cytokinesis	Biological process	24814515
EXOSC4	54512	exosome component 4	nucleolus	Cellular component	11110791
RNASE7	84659	ribonuclease, RNase A family, 7	lipopolysaccharide binding	Molecular function	20180804
C6orf58	352999	chromosome 6 open reading frame 58	multicellular organismal development	Biological process	-
CASKIN1	57524	CASK interacting protein 1	protein binding	Molecular function	21763699
GPM6B	2824	glycoprotein M6B	negative regulation of serotonin uptake	Biological process	-
DGKI	9162	diacylglycerol kinase, iota	perinuclear region of cytoplasm	Cellular component	-
KYNU	8942	kynureninase	pyridoxal phosphate binding	Molecular function	-
MLXIPL	51085	MLX interacting protein-like	sequence-specific DNA binding transcription factor activity	Molecular function	10780788
BTBD3	22903	BTB (POZ) domain containing 3	cerebral cortex development	Biological process	-
ZNF141	7700	zinc finger protein 141	anatomical structure morphogenesis	Biological process	8268908
AKR1A1	10327	aldo-keto reductase family 1, member A1 (aldehyde reductase)	apical plasma membrane	Cellular component	-
MAPKAPK2	9261	mitogen-activated protein kinase-activated protein kinase 2	G2 DNA damage checkpoint	Biological process	20932473
PTK7	5754	protein tyrosine kinase 7 (inactive)	cochlea morphogenesis	Biological process	-
NOTO	344022	notochord homeobox	DNA binding	Molecular function	-
AURKB	9212	aurora kinase B	cellular response to UV	Biological process	20959462
GOLT1B	51026	golgi transport 1B	bounding membrane of organelle	Cellular component	-
BMPER	168667	BMP binding endothelial regulator	blood vessel endothelial cell proliferation involved in sprouting angiogenesis	Biological process	18787191
MAGEB5	347541	melanoma antigen family B5	cellular_component	Cellular component	-
ACIN1	22985	apoptotic chromatin condensation inducer 1	poly(A) RNA binding	Molecular function	22658674
BRSK1	84446	BR serine/threonine kinase 1	tau-protein kinase activity	Molecular function	-
ISL1	3670	ISL LIM homeobox 1	positive regulation of interleukin-1 alpha production	Biological process	-
PPT1	5538	palmitoyl-protein thioesterase 1	sphingolipid catabolic process	Biological process	16542649
ACVR1B	91	activin A receptor, type IB	transmembrane receptor protein serine/threonine kinase activity	Molecular function	9032295
STAT3	6774	signal transducer and activator of transcription 3 (acute-phase response factor)	negative regulation of cell proliferation	Biological process	-
MST1R	4486	macrophage stimulating 1 receptor	transmembrane receptor protein tyrosine kinase signaling pathway	Biological process	-
OSBP	5007	oxysterol binding protein	nucleus	Cellular component	-
SNTA1	6640	syntrophin, alpha 1	syntrophin complex	Cellular component	21164104
CENPL	91687	centromere protein L	nucleoplasm	Cellular component	-
GLRA1	2741	glycine receptor, alpha 1	righting reflex	Biological process	-
GNAI2	2771	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	heterotrimeric G-protein complex	Cellular component	-
PLCE1	51196	phospholipase C, epsilon 1	cytoplasm	Cellular component	-
TRIM23	373	tripartite motif containing 23	identical protein binding	Molecular function	16189514
FLT1	2321	fms-related tyrosine kinase 1	VEGF-A-activated receptor activity	Molecular function	8605350
RRM2B	50484	ribonucleotide reductase M2 B (TP53 inducible)	metal ion binding	Molecular function	-
MAP3K13	9175	mitogen-activated protein kinase kinase kinase 13	protein kinase binding	Molecular function	9353328
ADIPOR1	51094	adiponectin receptor 1	leptin-mediated signaling pathway	Biological process	-
HSBP1	3281	heat shock factor binding protein 1	cytoskeleton	Cellular component	-
ING4	51147	inhibitor of growth family, member 4	histone H4-K16 acetylation	Biological process	16387653
CBY1	25776	chibby homolog 1 (Drosophila)	cardiac muscle cell differentiation	Biological process	-
TP53BP1	7158	tumor protein p53 binding protein 1	chromosome, telomeric region	Cellular component	15149599
ARL15	54622	ADP-ribosylation factor-like 15	intracellular	Cellular component	-
TAF8	129685	TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa	perinuclear region of cytoplasm	Cellular component	15870280
PHLDB2	90102	pleckstrin homology-like domain, family B, member 2	intermediate filament cytoskeleton	Cellular component	-
PNPO	55163	pyridoxamine 5'-phosphate oxidase	extracellular exosome	Cellular component	23376485
SLCO1C1	53919	solute carrier organic anion transporter family, member 1C1	organic anion transmembrane transporter activity	Molecular function	-
HIST1H3H	8357	histone cluster 1, H3h	chromatin silencing at rDNA	Biological process	-
NIPBL	25836	Nipped-B homolog (Drosophila)	metanephros development	Biological process	15146185
WDPCP	51057	WD repeat containing planar cell polarity effector	regulation of fibroblast migration	Biological process	-
CELSR2	1952	cadherin, EGF LAG seven-pass G-type receptor 2	Wnt signaling pathway	Biological process	-
EPRS	2058	glutamyl-prolyl-tRNA synthetase	glutamate-tRNA ligase activity	Molecular function	-
GCH1	2643	GTP cyclohydrolase 1	pteridine-containing compound biosynthetic process	Biological process	15721862
RUNX2	860	runt-related transcription factor 2	regulation of odontogenesis of dentin-containing tooth	Biological process	-
NAT2	10	N-acetyltransferase 2 (arylamine N-acetyltransferase)	cytosol	Cellular component	-
RTN4RL1	146760	reticulon 4 receptor-like 1	membrane raft	Cellular component	-
SOX17	64321	SRY (sex determining region Y)-box 17	protein heterodimerization activity	Molecular function	-
HOXC4	3221	homeobox C4	transcription, DNA-templated	Biological process	-
CDC42	998	cell division cycle 42	epidermal growth factor receptor signaling pathway	Biological process	-
ANGPT1	284	angiopoietin 1	positive regulation of cell adhesion	Biological process	-
NPHP1	4867	nephronophthisis 1 (juvenile)	motile cilium	Cellular component	16885411
NDST2	8509	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2	carbohydrate metabolic process	Biological process	-
YRDC	79693	yrdC N(6)-threonylcarbamoyltransferase domain containing	double-stranded RNA binding	Molecular function	-
GRM7	2917	glutamate receptor, metabotropic 7	dendritic shaft	Cellular component	-
CELF1	10658	CUGBP, Elav-like family member 1	positive regulation of multicellular organism growth	Biological process	-
OR4E2	26686	olfactory receptor, family 4, subfamily E, member 2	olfactory receptor activity	Molecular function	-
UNG	7374	uracil-DNA glycosylase	protein binding	Molecular function	10982866
SLC38A2	54407	solute carrier family 38, member 2	symporter activity	Molecular function	-
CDC23	8697	cell division cycle 23	protein binding	Molecular function	16189514
C2CD4B	388125	C2 calcium-dependent domain containing 4B	syntaxin binding	Molecular function	-
KITLG	4254	KIT ligand	extracellular region	Cellular component	-
SMAD3	4088	SMAD family member 3	gene expression	Biological process	-
OR9G9	504191	olfactory receptor, family 9, subfamily G, member 9	G-protein coupled receptor signaling pathway	Biological process	-
MDK	4192	midkine (neurite growth-promoting factor 2)	Notch signaling pathway	Biological process	-
NCAM1	4684	neural cell adhesion molecule 1	extracellular exosome	Cellular component	23376485
CDK7	1022	cyclin-dependent kinase 7	termination of RNA polymerase I transcription	Biological process	-
YBX3	8531	Y box binding protein 3	nucleus	Cellular component	22711822
ZBTB1	22890	zinc finger and BTB domain containing 1	B cell differentiation	Biological process	-
UPK3A	7380	uroplakin 3A	potassium ion homeostasis	Biological process	-
UHRF1	29128	ubiquitin-like with PHD and ring finger domains 1	nucleosomal histone binding	Molecular function	-
KCNK3	3777	potassium channel, two pore domain subfamily K, member 3	cellular response to hypoxia	Biological process	-
FIS1	51024	fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)	positive regulation of intrinsic apoptotic signaling pathway	Biological process	21183955
OGN	4969	osteoglycin	small molecule metabolic process	Biological process	-
UGT1A9	54600	UDP glucuronosyltransferase 1 family, polypeptide A9	flavonoid glucuronidation	Biological process	20056724
MMP27	64066	matrix metallopeptidase 27	calcium ion binding	Molecular function	-
SLC29A1	2030	solute carrier family 29 (equilibrative nucleoside transporter), member 1	nucleoside transmembrane transport	Biological process	8986748
TERF1	7013	telomeric repeat binding factor (NIMA-interacting) 1	positive regulation of apoptotic process	Biological process	11313893
DSG3	1830	desmoglein 3	calcium ion binding	Molecular function	-
FBXL20	84961	F-box and leucine-rich repeat protein 20	behavioral fear response	Biological process	-
MYT1	4661	myelin transcription factor 1	enhancer sequence-specific DNA binding	Molecular function	-
HOMER3	9454	homer scaffolding protein 3	protein binding	Molecular function	16098226
FAP	2191	fibroblast activation protein, alpha	cytoplasm	Cellular component	-
CCRL2	9034	chemokine (C-C motif) receptor-like 2	G-protein coupled receptor signaling pathway	Biological process	-
TRAPPC2B	10597	trafficking protein particle complex 2B	nucleus	Cellular component	-
HINFP	25988	histone H4 transcription factor	myoblast differentiation	Biological process	15541338
IL2	3558	interleukin 2	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
MMD2	221938	monocyte to macrophage differentiation-associated 2	positive regulation of protein kinase activity	Biological process	21968647
PKMYT1	9088	protein kinase, membrane associated tyrosine/threonine 1	Golgi apparatus	Cellular component	9001210
DNMT3B	1789	DNA (cytosine-5-)-methyltransferase 3 beta	DNA (cytosine-5-)-methyltransferase activity	Molecular function	10433969
PSMC6	5706	proteasome (prosome, macropain) 26S subunit, ATPase, 6	proteasome regulatory particle, base subcomplex	Cellular component	-
KPTN	11133	kaptin (actin binding protein)	actin filament organization	Biological process	-
ATP11B	23200	ATPase, class VI, type 11B	magnesium ion binding	Molecular function	-
NEDD8	4738	neural precursor cell expressed, developmentally down-regulated 8	protein neddylation	Biological process	10500095
CLCF1	23529	cardiotrophin-like cytokine factor 1	ciliary neurotrophic factor receptor binding	Molecular function	10966616
DDX42	11325	DEAD (Asp-Glu-Ala-Asp) box helicase 42	nuclear speck	Cellular component	-
NEUROD2	4761	neuronal differentiation 2	RNA polymerase II regulatory region sequence-specific DNA binding	Molecular function	-
PARN	5073	poly(A)-specific ribonuclease	nucleus	Cellular component	9736620
TCTN1	79600	tectonic family member 1	TCTN-B9D complex	Cellular component	-
WNT4	54361	wingless-type MMTV integration site family, member 4	immature T cell proliferation in thymus	Biological process	-
USF1	7391	upstream transcription factor 1	nucleus	Cellular component	-
TUBG1	7283	tubulin, gamma 1	G2/M transition of mitotic cell cycle	Biological process	-
DEFB121	245934	defensin, beta 121	molecular_function	Molecular function	-
SERPING1	710	serpin peptidase inhibitor, clade G (C1 inhibitor), member 1	blood circulation	Biological process	2365061
RNF14	9604	ring finger protein 14	positive regulation of transcription, DNA-templated	Biological process	15572661
NDUFS6	4726	NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)	mitochondrial respiratory chain complex I	Cellular component	15372108
PSMA7	5688	proteasome (prosome, macropain) subunit, alpha type, 7	mitotic cell cycle	Biological process	-
UBE2L3	7332	ubiquitin-conjugating enzyme E2L 3	transcription, DNA-templated	Biological process	-
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	genitalia morphogenesis	Biological process	-
ADAMTS20	80070	ADAM metallopeptidase with thrombospondin type 1 motif, 20	extracellular matrix organization	Biological process	-
ZBED4	9889	zinc finger, BED-type containing 4	nucleus	Cellular component	19369242
SLC2A13	114134	solute carrier family 2 (facilitated glucose transporter), member 13	transmembrane transport	Biological process	-
GFI1B	8328	growth factor independent 1B transcription repressor	myeloid cell differentiation	Biological process	-
TUBGCP3	10426	tubulin, gamma complex associated protein 3	protein binding	Molecular function	17959831
RPS28	6234	ribosomal protein S28	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Biological process	-
POLR1E	64425	polymerase (RNA) I polypeptide E, 53kDa	transcription initiation from RNA polymerase I promoter	Biological process	-
APOM	55937	apolipoprotein M	cholesterol homeostasis	Biological process	15793583
GRHL2	79977	grainyhead-like 2 (Drosophila)	epithelium migration	Biological process	-
CDC42BPB	9578	CDC42 binding protein kinase beta (DMPK-like)	signal transduction	Biological process	9418861
S100A6	6277	S100 calcium binding protein A6	cytoplasm	Cellular component	16130169
RPL18	6141	ribosomal protein L18	structural constituent of ribosome	Molecular function	12962325
STX4	6810	syntaxin 4	long-term synaptic potentiation	Biological process	20434989
ITGA3	3675	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	integrin complex	Cellular component	1655803
CCDC89	220388	coiled-coil domain containing 89	cytoplasm	Cellular component	-
G6PC	2538	glucose-6-phosphatase, catalytic subunit	phosphorylated carbohydrate dephosphorylation	Biological process	-
HDAC2	3066	histone deacetylase 2	negative regulation of intrinsic apoptotic signaling pathway	Biological process	-
YBX2	51087	Y box binding protein 2	chromatin binding	Molecular function	-
GAB1	2549	GRB2-associated binding protein 1	interleukin-6-mediated signaling pathway	Biological process	-
C2CD5	9847	C2 calcium-dependent domain containing 5	insulin receptor signaling pathway via phosphatidylinositol 3-kinase	Biological process	-
MAP6D1	79929	MAP6 domain containing 1	N-terminal peptidyl-L-cysteine N-palmitoylation	Biological process	-
HNF1A	6927	HNF1 homeobox A	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
RAB3C	115827	RAB3C, member RAS oncogene family	cytosol	Cellular component	-
KEL	3792	Kell blood group, metallo-endopeptidase	cellular calcium ion homeostasis	Biological process	-
APC	324	adenomatous polyposis coli	microtubule plus-end	Cellular component	-
PDZD11	51248	PDZ domain containing 11	synapse	Cellular component	-
PSMA2	5683	proteasome (prosome, macropain) subunit, alpha type, 2	programmed cell death	Biological process	-
CYP17A1	1586	cytochrome P450, family 17, subfamily A, polypeptide 1	hormone biosynthetic process	Biological process	22266943
IMP3	55272	IMP3, U3 small nucleolar ribonucleoprotein	small ribosomal subunit	Cellular component	-
DRD5	1816	dopamine receptor D5	regulation of female receptivity	Biological process	-
DCN	1634	decorin	positive regulation of autophagy	Biological process	23798385
CDC7	8317	cell division cycle 7	cytoplasm	Cellular component	9250678
SLC24A3	57419	solute carrier family 24 (sodium/potassium/calcium exchanger), member 3	transmembrane transport	Biological process	-
NXF2	56001	nuclear RNA export factor 2	nucleus	Cellular component	-
NFXL1	152518	nuclear transcription factor, X-box binding-like 1	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	-
GPC5	2262	glypican 5	glycosaminoglycan catabolic process	Biological process	-
PLA2G4C	8605	phospholipase A2, group IVC (cytosolic, calcium-independent)	cell cortex	Cellular component	-
RAC3	5881	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	GTP binding	Molecular function	-
MAPK8IP1	9479	mitogen-activated protein kinase 8 interacting protein 1	negative regulation of intrinsic apoptotic signaling pathway	Biological process	-
ZMYM5	9205	zinc finger, MYM-type 5	zinc ion binding	Molecular function	-
DGKB	1607	diacylglycerol kinase, beta 90kDa	blood coagulation	Biological process	-
ABHD5	51099	abhydrolase domain containing 5	cytosol	Cellular component	-
PRAMEF1	65121	PRAME family member 1	negative regulation of transcription, DNA-templated	Biological process	-
CDK5RAP1	51654	CDK5 regulatory subunit associated protein 1	tRNA modification	Biological process	-
PTGS2	5743	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	positive regulation of synaptic plasticity	Biological process	-
PRPF4	9128	pre-mRNA processing factor 4	protein binding	Molecular function	19615732
IMPA1	3612	inositol(myo)-1(or 4)-monophosphatase 1	phosphate-containing compound metabolic process	Biological process	1377913
NRG3	10718	neuregulin 3	regulation of cell growth	Biological process	9275162
TBL1Y	90665	transducin (beta)-like 1, Y-linked	response to estrogen	Biological process	-
CLEC17A	388512	C-type lectin domain family 17, member A	mannose binding	Molecular function	19419970
KCNN4	3783	potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4	cell volume homeostasis	Biological process	-
TRAP1	10131	TNF receptor-associated protein 1	protein binding	Molecular function	23564345
TRIP4	9325	thyroid hormone receptor interactor 4	toxin transport	Biological process	-
LIG4	3981	ligase IV, DNA, ATP-dependent	DNA ligase IV complex	Cellular component	9809069
SDCBP	6386	syndecan binding protein (syntenin)	identical protein binding	Molecular function	22673509
RAB3D	9545	RAB3D, member RAS oncogene family	intracellular protein transport	Biological process	-
ESD	2098	esterase D	plasma membrane	Cellular component	-
GHRHR	2692	growth hormone releasing hormone receptor	hormone metabolic process	Biological process	-
SEC31A	22872	SEC31 homolog A (S. cerevisiae)	cytoplasm	Cellular component	-
KCNA5	3741	potassium channel, voltage gated shaker related subfamily A, member 5	membrane repolarization during bundle of His cell action potential	Biological process	23264583
NUP210	23225	nucleoporin 210kDa	hexose transport	Biological process	-
CYP2E1	1571	cytochrome P450, family 2, subfamily E, polypeptide 1	Golgi membrane	Cellular component	-
CNOT2	4848	CCR4-NOT transcription complex, subunit 2	CCR4-NOT complex	Cellular component	19558367
UCP3	7352	uncoupling protein 3 (mitochondrial, proton carrier)	mitochondrial transport	Biological process	-
SMOC1	64093	SPARC related modular calcium binding 1	protein binding	Molecular function	23088713
TBX3	6926	T-box 3	mammary gland development	Biological process	12116211
FCN1	2219	ficolin (collagen/fibrinogen domain containing) 1	extrinsic component of external side of plasma membrane	Cellular component	21037097
HUS1B	135458	HUS1 checkpoint homolog b (S. pombe)	mitotic DNA replication checkpoint	Biological process	-
PLA2G4A	5321	phospholipase A2, group IVA (cytosolic, calcium-dependent)	cytoplasm	Cellular component	-
PRRX2	51450	paired related homeobox 2	positive regulation of mesenchymal cell proliferation	Biological process	-
PLA2G2C	391013	phospholipase A2, group IIC	lipid catabolic process	Biological process	-
PTGIS	5740	prostaglandin I2 (prostacyclin) synthase	small molecule metabolic process	Biological process	-
NUP93	9688	nucleoporin 93kDa	glucose transport	Biological process	-
ADRA2A	150	adrenoceptor alpha 2A	thermoception	Biological process	-
DRC1	92749	dynein regulatory complex subunit 1	cytoskeleton	Cellular component	-
DNMT1	1786	DNA (cytosine-5-)-methyltransferase 1	C-5 methylation of cytosine	Biological process	-
KCNJ9	3765	potassium channel, inwardly rectifying subfamily J, member 9	PDZ domain binding	Molecular function	-
SKP1	6500	S-phase kinase-associated protein 1	protein binding	Molecular function	11099048
NOTCH1	4851	notch 1	cardiac epithelial to mesenchymal transition	Biological process	-
HNF4A	3172	hepatocyte nuclear factor 4, alpha	triglyceride homeostasis	Biological process	-
COL7A1	1294	collagen, type VII, alpha 1	extracellular space	Cellular component	22664934
ATP4B	496	ATPase, H+/K+ exchanging, beta polypeptide	sodium ion transport	Biological process	-
LHFPL1	340596	lipoma HMGIC fusion partner-like 1	integral component of membrane	Cellular component	-
TGFB1	7040	transforming growth factor, beta 1	positive regulation of chemotaxis	Biological process	18555217
RBP3	5949	retinol binding protein 3, interstitial	extracellular space	Cellular component	23486466
DDX17	10521	DEAD (Asp-Glu-Ala-Asp) box helicase 17	RNA secondary structure unwinding	Biological process	-
SSTR5	6755	somatostatin receptor 5	neuropeptide signaling pathway	Biological process	-
FEN1	2237	flap structure-specific endonuclease 1	double-stranded DNA exodeoxyribonuclease activity	Molecular function	8131753
JAK2	3717	Janus kinase 2	host programmed cell death induced by symbiont	Biological process	-
LINGO1	84894	leucine rich repeat and Ig domain containing 1	protein kinase B signaling	Biological process	-
ATP6V1B2	526	ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2	plasma membrane	Cellular component	-
ZKSCAN5	23660	zinc finger with KRAB and SCAN domains 5	regulation of transcription, DNA-templated	Biological process	10585779
POLL	27343	polymerase (DNA directed), lambda	DNA biosynthetic process	Biological process	-
CIDEC	63924	cell death-inducing DFFA-like effector c	execution phase of apoptosis	Biological process	12429024
KLHL17	339451	kelch-like family member 17	actin cytoskeleton	Cellular component	-
CD163	9332	CD163 molecule	acute-phase response	Biological process	-
KCTD5	54442	potassium channel tetramerization domain containing 5	cytosol	Cellular component	18573101
DAD1	1603	defender against cell death 1	apoptotic process	Biological process	-
SRPRB	58477	signal recognition particle receptor, B subunit	endoplasmic reticulum unfolded protein response	Biological process	-
ENC1	8507	ectodermal-neural cortex 1 (with BTB domain)	nucleolus	Cellular component	-
ID4	3400	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	cellular protein localization	Biological process	-
TRAF2	7186	TNF receptor-associated factor 2	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	Biological process	14685163
DUOX2	50506	dual oxidase 2	hydrogen peroxide catabolic process	Biological process	-
SLC8B1	80024	solute carrier family 8 (sodium/lithium/calcium exchanger), member B1	mitochondrial calcium ion homeostasis	Biological process	20018762
CBR1	873	carbonyl reductase 1	arachidonic acid metabolic process	Biological process	-
FRMD7	90167	FERM domain containing 7	cytoskeleton	Cellular component	-
ME1	4199	malic enzyme 1, NADP(+)-dependent, cytosolic	manganese ion binding	Molecular function	7622060
PITX2	5308	paired-like homeodomain 2	nucleoplasm	Cellular component	-
HTR2B	3357	5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled	calcium-mediated signaling	Biological process	8882600
PDP2	57546	pyruvate dehyrogenase phosphatase catalytic subunit 2	small molecule metabolic process	Biological process	-
ACTN4	81	actinin, alpha 4	extracellular space	Cellular component	16502470
PDE6B	5158	phosphodiesterase 6B, cGMP-specific, rod, beta	visual perception	Biological process	-
VPS33B	26276	vacuolar protein sorting 33 homolog B (yeast)	platelet alpha granule	Cellular component	16123220
IMP4	92856	IMP4, U3 small nucleolar ribonucleoprotein	Mpp10 complex	Cellular component	-
RAI1	10743	retinoic acid induced 1	nucleus	Cellular component	-
POLL	27343	polymerase (DNA directed), lambda	somatic hypermutation of immunoglobulin genes	Biological process	10982892
ASPN	54829	asporin	bone mineralization	Biological process	19589127
UIMC1	51720	ubiquitin interaction motif containing 1	retinoid X receptor binding	Molecular function	-
ATP6V1B1	525	ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1	pH reduction	Biological process	19478356
WIPI1	55062	WD repeat domain, phosphoinositide interacting 1	phosphatidylinositol-3,5-bisphosphate binding	Molecular function	20505359
ZNF585B	92285	zinc finger protein 585B	sequence-specific DNA binding transcription factor activity	Molecular function	-
SOX4	6659	SRY (sex determining region Y)-box 4	cellular response to glucose stimulus	Biological process	-
TNXA	7146	tenascin XA (pseudogene)	biological_process	Biological process	-
CHRNB2	1141	cholinergic receptor, nicotinic, beta 2 (neuronal)	associative learning	Biological process	-
ACVR2A	92	activin A receptor, type IIA	embryonic skeletal system development	Biological process	-
COPZ2	51226	coatomer protein complex, subunit zeta 2	vesicle-mediated transport	Biological process	-
ANGPT4	51378	angiopoietin 4	positive regulation of angiogenesis	Biological process	15284220
KLK7	5650	kallikrein-related peptidase 7	extracellular matrix disassembly	Biological process	-
RAD51	5888	RAD51 recombinase	cellular response to DNA damage stimulus	Biological process	23509288
COL6A3	1293	collagen, type VI, alpha 3	extracellular matrix	Cellular component	22261194
SUMO1	7341	small ubiquitin-like modifier 1	protein sumoylation	Biological process	-
TMEM121	80757	transmembrane protein 121	integral component of membrane	Cellular component	-
KRT38	8687	keratin 38, type I	structural molecule activity	Molecular function	-
GORAB	92344	golgin, RAB6-interacting	protein binding	Molecular function	15781263
NSUN5	55695	NOP2/Sun domain family, member 5	methylation	Biological process	-
FZD10	11211	frizzled class receptor 10	cytoplasm	Cellular component	16007199
TLR2	7097	toll-like receptor 2	lipopolysaccharide receptor activity	Molecular function	11518816
S100A13	6284	S100 calcium binding protein A13	protein binding	Molecular function	12746488
EVI2A	2123	ecotropic viral integration site 2A	signal transduction	Biological process	2117566
RGMB	285704	repulsive guidance molecule family member b	coreceptor activity	Molecular function	-
XPC	7508	xeroderma pigmentosum, complementation group C	protein binding	Molecular function	10488153
RHOH	399	ras homolog family member H	small GTPase mediated signal transduction	Biological process	-
IL13	3596	interleukin 13	extracellular space	Cellular component	16275384
FTCD	10841	formimidoyltransferase cyclodeaminase	protein binding	Molecular function	25416956
MSRA	4482	methionine sulfoxide reductase A	extracellular exosome	Cellular component	19056867
SAFB2	9667	scaffold attachment factor B2	regulation of transcription, DNA-templated	Biological process	-
CALHM2	51063	calcium homeostasis modulator 2	cation transmembrane transport	Biological process	-
SLC32A1	140679	solute carrier family 32 (GABA vesicular transporter), member 1	glycine transport	Biological process	-
HSP90AA1	3320	heat shock protein 90kDa alpha (cytosolic), class A member 1	protein import into mitochondrial outer membrane	Biological process	15644312
CCR7	1236	chemokine (C-C motif) receptor 7	positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation	Biological process	-
ACACB	32	acetyl-CoA carboxylase beta	small molecule metabolic process	Biological process	-
LCP1	3936	lymphocyte cytosolic protein 1 (L-plastin)	wound healing, spreading of cells	Biological process	16636079
HENMT1	113802	HEN1 methyltransferase homolog 1 (Arabidopsis)	RNA methyltransferase activity	Molecular function	-
SPATA22	84690	spermatogenesis associated 22	protein binding	Molecular function	25416956
IRF2	3660	interferon regulatory factor 2	cytokine-mediated signaling pathway	Biological process	-
VWA1	64856	von Willebrand factor A domain containing 1	behavioral response to pain	Biological process	-
SLC52A3	113278	solute carrier family 52 (riboflavin transporter), member 3	integral component of plasma membrane	Cellular component	20463145
HSP90AA1	3320	heat shock protein 90kDa alpha (cytosolic), class A member 1	positive regulation of cardiac muscle contraction	Biological process	-
PPP2R3C	55012	protein phosphatase 2, regulatory subunit B'', gamma	microtubule cytoskeleton organization	Biological process	-
KIAA1715	80856	KIAA1715	endoplasmic reticulum membrane	Cellular component	24223779
HOXB4	3214	homeobox B4	embryonic skeletal system morphogenesis	Biological process	-
COL14A1	7373	collagen, type XIV, alpha 1	collagen binding	Molecular function	2187872
SNX9	51429	sorting nexin 9	positive regulation of protein oligomerization	Biological process	15703209
ZRANB1	54764	zinc finger, RAN-binding domain containing 1	Wnt signaling pathway	Biological process	-
SNRPE	6635	small nuclear ribonucleoprotein polypeptide E	RNA splicing	Biological process	-
U2AF1	7307	U2 small nuclear RNA auxiliary factor 1	Cajal body	Cellular component	1388271
MYBPC3	4607	myosin binding protein C, cardiac	heart morphogenesis	Biological process	7493025
PI4KB	5298	phosphatidylinositol 4-kinase, catalytic, beta	phosphatidylinositol phosphorylation	Biological process	-
FAM50A	9130	family with sequence similarity 50, member A	nucleus	Cellular component	9339379
MEGF8	1954	multiple EGF-like-domains 8	extracellular exosome	Cellular component	19056867
NKX2-3	159296	NK2 homeobox 3	gland morphogenesis	Biological process	-
ARID4B	51742	AT rich interactive domain 4B (RBP1-like)	biological_process	Biological process	-
FAXC	84553	failed axon connections homolog (Drosophila)	integral component of membrane	Cellular component	-
RAD51	5888	RAD51 recombinase	cytoplasm	Cellular component	-
ALOX15B	247	arachidonate 15-lipoxygenase, type B	linoleate 13S-lipoxygenase activity	Molecular function	10542053
SHROOM2	357	shroom family member 2	beta-catenin binding	Molecular function	16684770
ZBTB1	22890	zinc finger and BTB domain containing 1	nuclear body	Cellular component	20797634
NOX3	50508	NADPH oxidase 3	plasma membrane	Cellular component	-
FADD	8772	Fas (TNFRSF6)-associated via death domain	protein binding	Molecular function	10442631
MAP2K6	5608	mitogen-activated protein kinase kinase 6	nucleoplasm	Cellular component	-
WFDC10B	280664	WAP four-disulfide core domain 10B	negative regulation of peptidase activity	Biological process	-
OPRL1	4987	opiate receptor-like 1	neuron projection	Cellular component	-
PPP1R11	6992	protein phosphatase 1, regulatory (inhibitor) subunit 11	negative regulation of protein dephosphorylation	Biological process	-
VEGFA	7422	vascular endothelial growth factor A	platelet degranulation	Biological process	-
FGR	2268	FGR proto-oncogene, Src family tyrosine kinase	mitochondrial intermembrane space	Cellular component	-
STXBP6	29091	syntaxin binding protein 6 (amisyn)	exocyst localization	Biological process	-
BMP2	650	bone morphogenetic protein 2	telencephalon development	Biological process	9187146
SLC26A11	284129	solute carrier family 26 (anion exchanger), member 11	anion:anion antiporter activity	Molecular function	-
MYO1C	4641	myosin IC	extracellular exosome	Cellular component	19056867
TRPC7	57113	transient receptor potential cation channel, subfamily C, member 7	plasma membrane	Cellular component	-
IQGAP1	8826	IQ motif containing GTPase activating protein 1	cell leading edge	Cellular component	-
DOCK2	1794	dedicator of cytokinesis 2	T cell receptor binding	Molecular function	12176041
GJB3	2707	gap junction protein, beta 3, 31kDa	cell communication	Biological process	-
PRRG4	79056	proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)	molecular_function	Molecular function	-
UBP1	7342	upstream binding protein 1 (LBP-1a)	nucleoplasm	Cellular component	-
PRPF40A	55660	PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)	cell cycle	Biological process	-
NPHP4	261734	nephronophthisis 4	visual behavior	Biological process	12205563
BEX5	340542	brain expressed, X-linked 5	protein binding	Molecular function	25416956
TBX3	6926	T-box 3	skeletal system development	Biological process	9207801
NMNAT2	23057	nicotinamide nucleotide adenylyltransferase 2	nicotinate-nucleotide adenylyltransferase activity	Molecular function	16118205
PNKP	11284	polynucleotide kinase 3'-phosphatase	purine nucleotide binding	Molecular function	10446193
LOC81691	81691	exonuclease NEF-sp	nucleolus	Cellular component	-
RALGAPA1	253959	Ral GTPase activating protein, alpha subunit 1 (catalytic)	protein heterodimerization activity	Molecular function	19520869
POLG2	11232	polymerase (DNA directed), gamma 2, accessory subunit	DNA biosynthetic process	Biological process	9153213
CHRNB2	1141	cholinergic receptor, nicotinic, beta 2 (neuronal)	plasma membrane	Cellular component	-
CD47	961	CD47 molecule	thrombospondin receptor activity	Molecular function	15700281
FGF23	8074	fibroblast growth factor 23	growth factor activity	Molecular function	-
OR5B12	390191	olfactory receptor, family 5, subfamily B, member 12	sensory perception of smell	Biological process	-
OBSCN	84033	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	Z disc	Cellular component	11717165
ECHDC2	55268	enoyl CoA hydratase domain containing 2	lyase activity	Molecular function	-
C5AR1	728	complement component 5a receptor 1	positive regulation of epithelial cell proliferation	Biological process	22496247
MMP17	4326	matrix metallopeptidase 17 (membrane-inserted)	enzyme activator activity	Molecular function	8640782
SCX	642658	scleraxis basic helix-loop-helix transcription factor	cellular response to BMP stimulus	Biological process	-
GPD1	2819	glycerol-3-phosphate dehydrogenase 1 (soluble)	extracellular exosome	Cellular component	19056867
RPL24	6152	ribosomal protein L24	exit from mitosis	Biological process	-
LMBR1	64327	limb development membrane protein 1	integral component of membrane	Cellular component	-
G0S2	50486	G0/G1 switch 2	cellular lipid metabolic process	Biological process	-
MGAT2	4247	mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity	Molecular function	-
OR5D18	219438	olfactory receptor, family 5, subfamily D, member 18	plasma membrane	Cellular component	-
DYNLT3	6990	dynein, light chain, Tctex-type 3	mitotic nuclear division	Biological process	-
APLN	8862	apelin	negative regulation of blood pressure	Biological process	-
RAB40B	10966	RAB40B, member RAS oncogene family	intracellular protein transport	Biological process	-
SLC5A3	6526	solute carrier family 5 (sodium/myo-inositol cotransporter), member 3	plasma membrane	Cellular component	-
SLC30A4	7782	solute carrier family 30 (zinc transporter), member 4	endosome membrane	Cellular component	-
ANO9	338440	anoctamin 9	plasma membrane	Cellular component	-
PCDHB9	56127	protocadherin beta 9	calcium ion binding	Molecular function	-
SSH1	54434	slingshot protein phosphatase 1	cytoplasm	Cellular component	-
ZFR	51663	zinc finger RNA binding protein	protein binding	Molecular function	20195357
RELA	5970	v-rel avian reticuloendotheliosis viral oncogene homolog A	identical protein binding	Molecular function	10498867
USP14	9097	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)	tRNA guanylyltransferase activity	Molecular function	8579355
ASIC5	51802	acid sensing (proton gated) ion channel family member 5	hydrogen ion channel activity	Molecular function	-
NFE2L3	9603	nuclear factor, erythroid 2-like 3	transcription coactivator activity	Molecular function	10037736
BFSP2	8419	beaded filament structural protein 2, phakinin	plasma membrane	Cellular component	-
LDHC	3948	lactate dehydrogenase C	cytoplasm	Cellular component	-
ATM	472	ATM serine/threonine kinase	double-strand break repair	Biological process	-
RAB26	25837	RAB26, member RAS oncogene family	GTP binding	Molecular function	-
ZNF296	162979	zinc finger protein 296	metal ion binding	Molecular function	-
F11R	50848	F11 receptor	inflammatory response	Biological process	10395639
TUBB	203068	tubulin, beta class I	protein polymerization	Biological process	-
CXCL3	2921	chemokine (C-X-C motif) ligand 3	inflammatory response	Biological process	-
ALDH3B1	221	aldehyde dehydrogenase 3 family, member B1	protein binding	Molecular function	25416956
KIF16B	55614	kinesin family member 16B	early endosome membrane	Cellular component	-
APOLD1	81575	apolipoprotein L domain containing 1	endothelial cell activation	Biological process	-
PAFAH1B2	5049	platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)	cytoplasm	Cellular component	16130169
ILF3	3609	interleukin enhancer binding factor 3, 90kDa	double-stranded RNA binding	Molecular function	10574923
SLC17A4	10050	solute carrier family 17, member 4	membrane	Cellular component	10319585
FER	2241	fer (fps/fes related) tyrosine kinase	protein binding	Molecular function	15226396
IFIT3	3437	interferon-induced protein with tetratricopeptide repeats 3	protein binding	Molecular function	16189514
ABCC4	10257	ATP-binding cassette, sub-family C (CFTR/MRP), member 4	ATP binding	Molecular function	-
SIX1	6495	SIX homeobox 1	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	15141091
WDR5	11091	WD repeat domain 5	protein binding	Molecular function	12670868
PROCR	10544	protein C receptor, endothelial	extracellular region	Cellular component	-
CAT	847	catalase	NADP binding	Molecular function	10656833
WIPF3	644150	WAS/WASL interacting protein family, member 3	actin binding	Molecular function	-
ABCF1	23	ATP-binding cassette, sub-family F (GCN20), member 1	ribosome biogenesis	Biological process	19570978
CARD14	79092	caspase recruitment domain family, member 14	tumor necrosis factor-mediated signaling pathway	Biological process	21302310
CAV3	859	caveolin 3	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	22879586
STXBP6	29091	syntaxin binding protein 6 (amisyn)	Golgi to plasma membrane transport	Biological process	-
VNN1	8876	vanin 1	single organismal cell-cell adhesion	Biological process	11491533
MYH9	4627	myosin, heavy chain 9, non-muscle	COP9 signalosome	Cellular component	18850735
ERBB3	2065	erb-b2 receptor tyrosine kinase 3	heart development	Biological process	-
CPM	1368	carboxypeptidase M	anatomical structure morphogenesis	Biological process	7797563
MTOR	2475	mechanistic target of rapamycin (serine/threonine kinase)	cytoplasm	Cellular component	11853878
OR10G7	390265	olfactory receptor, family 10, subfamily G, member 7	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
RAB3C	115827	RAB3C, member RAS oncogene family	perinuclear region of cytoplasm	Cellular component	19717423
PRKAG3	53632	protein kinase, AMP-activated, gamma 3 non-catalytic subunit	glucose transport	Biological process	-
TGM3	7053	transglutaminase 3	peptide cross-linking	Biological process	12679341
RNMT	8731	RNA (guanine-7-) methyltransferase	7-methylguanosine mRNA capping	Biological process	-
TNNT2	7139	troponin T type 2 (cardiac)	protein binding	Molecular function	25416956
OR8B4	283162	olfactory receptor, family 8, subfamily B, member 4 (gene/pseudogene)	G-protein coupled receptor signaling pathway	Biological process	-
RNF34	80196	ring finger protein 34, E3 ubiquitin protein ligase	protein ubiquitination	Biological process	22064484
SLC12A1	6557	solute carrier family 12 (sodium/potassium/chloride transporter), member 1	ion transport	Biological process	-
OR4D6	219983	olfactory receptor, family 4, subfamily D, member 6	transmembrane signaling receptor activity	Molecular function	-
SET	6418	SET nuclear proto-oncogene	mitotic cell cycle	Biological process	-
STRN3	29966	striatin, calmodulin binding protein 3	protein phosphatase type 2A complex	Cellular component	18782753
GABRA2	2555	gamma-aminobutyric acid (GABA) A receptor, alpha 2	benzodiazepine receptor activity	Molecular function	8391122
AGTR1	185	angiotensin II receptor, type 1	phospholipase C-activating G-protein coupled receptor signaling pathway	Biological process	17159080
NUP62	23636	nucleoporin 62kDa	positive regulation of transcription, DNA-templated	Biological process	-
MRPS14	63931	mitochondrial ribosomal protein S14	mitochondrial translational initiation	Biological process	-
ARG1	383	arginase 1	collagen biosynthetic process	Biological process	-
SASH1	23328	SAM and SH3 domain containing 1	positive regulation of endothelial cell migration	Biological process	23776175
AP2S1	1175	adaptor-related protein complex 2, sigma 1 subunit	viral process	Biological process	-
INS	3630	insulin	acute-phase response	Biological process	14739855
AKAP10	11216	A kinase (PRKA) anchor protein 10	plasma membrane	Cellular component	-
SDC2	6383	syndecan 2	Golgi lumen	Cellular component	-
G0S2	50486	G0/G1 switch 2	protein binding	Molecular function	19706769
LY96	23643	lymphocyte antigen 96	toll-like receptor signaling pathway	Biological process	-
DCN	1634	decorin	placenta development	Biological process	-
PRNP	5621	prion protein	cell cycle arrest	Biological process	-
PSMD12	5718	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
SFN	2810	stratifin	transcription initiation from RNA polymerase II promoter	Biological process	-
PLA2G4A	5321	phospholipase A2, group IVA (cytosolic, calcium-dependent)	icosanoid metabolic process	Biological process	9430701
GLB1L3	112937	galactosidase, beta 1-like 3	carbohydrate metabolic process	Biological process	-
FCGR2A	2212	Fc fragment of IgG, low affinity IIa, receptor (CD32)	Fc-gamma receptor signaling pathway involved in phagocytosis	Biological process	-
PTGS2	5743	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	decidualization	Biological process	-
IWS1	55677	IWS1 homolog (S. cerevisiae)	mRNA transport	Biological process	-
CTSC	1075	cathepsin C	cysteine-type endopeptidase activity	Molecular function	-
KATNA1	11104	katanin p60 (ATPase containing) subunit A 1	neuronal cell body	Cellular component	-
TRIM40	135644	tripartite motif containing 40	negative regulation of NIK/NF-kappaB signaling	Biological process	21474709
LYN	4067	LYN proto-oncogene, Src family tyrosine kinase	cellular response to DNA damage stimulus	Biological process	10891478
MMS19	64210	MMS19 nucleotide excision repair homolog (S. cerevisiae)	iron-sulfur cluster assembly	Biological process	22678361
KCTD6	200845	potassium channel tetramerization domain containing 6	protein homooligomerization	Biological process	-
PPP1CA	5499	protein phosphatase 1, catalytic subunit, alpha isozyme	cell division	Biological process	-
CNTRL	11064	centriolin	mitotic cell cycle	Biological process	-
ZNF19	7567	zinc finger protein 19	regulation of transcription, DNA-templated	Biological process	7557990
FCGRT	2217	Fc fragment of IgG, receptor, transporter, alpha	antigen processing and presentation	Biological process	-
HMGB2	3148	high mobility group box 2	condensed chromosome	Cellular component	12925773
NUP85	79902	nucleoporin 85kDa	gene expression	Biological process	-
PAX5	5079	paired box 5	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
OR11H4	390442	olfactory receptor, family 11, subfamily H, member 4	G-protein coupled receptor activity	Molecular function	-
TNFRSF10A	8797	tumor necrosis factor receptor superfamily, member 10a	necroptotic process	Biological process	-
LEO1	123169	Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	Cdc73/Paf1 complex	Cellular component	16307923
SSX2IP	117178	synovial sarcoma, X breakpoint 2 interacting protein	centrosome organization	Biological process	23816619
CLDN7	1366	claudin 7	basolateral plasma membrane	Cellular component	-
PTPRD	5789	protein tyrosine phosphatase, receptor type, D	presynaptic membrane assembly	Biological process	-
CYSLTR1	10800	cysteinyl leukotriene receptor 1	protein binding	Molecular function	21203429
ZNF578	147660	zinc finger protein 578	metal ion binding	Molecular function	-
CANT1	124583	calcium activated nucleotidase 1	calcium ion binding	Molecular function	-
EHMT2	10919	euchromatic histone-lysine N-methyltransferase 2	regulation of DNA replication	Biological process	22387026
RALBP1	10928	ralA binding protein 1	ATPase activity	Molecular function	10924126
MCM5	4174	minichromosome maintenance complex component 5	DNA strand elongation involved in DNA replication	Biological process	-
PJA1	64219	praja ring finger 1, E3 ubiquitin protein ligase	ligase activity	Molecular function	-
OLFM4	10562	olfactomedin 4	positive regulation of substrate adhesion-dependent cell spreading	Biological process	16566923
AP5S1	55317	adaptor-related protein complex 5, sigma 1 subunit	AP-type membrane coat adaptor complex	Cellular component	22022230
KIF2B	84643	kinesin family member 2B	mitotic cell cycle	Biological process	-
EMP2	2013	epithelial membrane protein 2	regulation of glomerular filtration	Biological process	24814193
LIN7B	64130	lin-7 homolog B (C. elegans)	intracellular	Cellular component	-
ANAPC2	29882	anaphase promoting complex subunit 2	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
MEGF8	1954	multiple EGF-like-domains 8	embryonic limb morphogenesis	Biological process	-
RACGAP1	29127	Rac GTPase activating protein 1	positive regulation of GTPase activity	Biological process	15642749
SLC30A5	64924	solute carrier family 30 (zinc transporter), member 5	nucleolus	Cellular component	-
NRCAM	4897	neuronal cell adhesion molecule	axonal fasciculation	Biological process	8812479
HSPB2	3316	heat shock 27kDa protein 2	cytoplasm	Cellular component	19464326
CCL5	6352	chemokine (C-C motif) ligand 5	cellular response to fibroblast growth factor stimulus	Biological process	9407497
MAGI2	9863	membrane associated guanylate kinase, WW and PDZ domain containing 2	cytoplasm	Cellular component	11526121
T	6862	T, brachyury homolog (mouse)	canonical Wnt signaling pathway	Biological process	-
PQLC3	130814	PQ loop repeat containing 3	dolichol-linked oligosaccharide biosynthetic process	Biological process	-
ZNF141	7700	zinc finger protein 141	transcription from RNA polymerase II promoter	Biological process	8268908
CHST10	9486	carbohydrate sulfotransferase 10	carbohydrate biosynthetic process	Biological process	-
FOXP3	50943	forkhead box P3	negative regulation of interferon-gamma biosynthetic process	Biological process	-
CUL3	8452	cullin 3	cytosol	Cellular component	-
PPP1R9B	84687	protein phosphatase 1, regulatory subunit 9B	lamellipodium	Cellular component	19151759
MPP5	64398	membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)	cell-cell junction organization	Biological process	-
MYO1F	4542	myosin IF	actin binding	Molecular function	9119401
TMEM106B	54664	transmembrane protein 106B	dendrite morphogenesis	Biological process	24357581
WNT3A	89780	wingless-type MMTV integration site family, member 3A	positive regulation of cardiac muscle cell differentiation	Biological process	20559569
LEF1	51176	lymphoid enhancer-binding factor 1	negative regulation of striated muscle tissue development	Biological process	-
HRK	8739	harakiri, BCL2 interacting protein	positive regulation of release of cytochrome c from mitochondria	Biological process	21041309
PDZD11	51248	PDZ domain containing 11	protein binding	Molecular function	12763866
APTX	54840	aprataxin	cytoplasm	Cellular component	-
TLR4	7099	toll-like receptor 4	lipopolysaccharide-mediated signaling pathway	Biological process	10880523
EGR3	1960	early growth response 3	regulation of transcription, DNA-templated	Biological process	-
MAS1L	116511	MAS1 proto-oncogene like, G protein-coupled receptor	integral component of membrane	Cellular component	1723144
FXYD3	5349	FXYD domain containing ion transport regulator 3	integral component of plasma membrane	Cellular component	7836447
LST1	7940	leukocyte specific transcript 1	dendrite development	Biological process	11478849
MTIF2	4528	mitochondrial translational initiation factor 2	nucleoplasm	Cellular component	-
CAGE1	285782	cancer antigen 1	protein binding	Molecular function	25416956
FADD	8772	Fas (TNFRSF6)-associated via death domain	cell surface receptor signaling pathway	Biological process	-
RAPGEF2	9693	Rap guanine nucleotide exchange factor (GEF) 2	negative regulation of melanin biosynthetic process	Biological process	-
AHI1	54806	Abelson helper integration site 1	protein binding	Molecular function	18633336
TOE1	114034	target of EGR1, member 1 (nuclear)	nucleic acid binding	Molecular function	-
MED17	9440	mediator complex subunit 17	transcription factor complex	Cellular component	9989412
SRP19	6728	signal recognition particle 19kDa	SRP-dependent cotranslational protein targeting to membrane	Biological process	-
TSFM	10102	Ts translation elongation factor, mitochondrial	mitochondrion	Cellular component	-
PRPF6	24148	pre-mRNA processing factor 6	poly(A) RNA binding	Molecular function	22658674
TDP2	51567	tyrosyl-DNA phosphodiesterase 2	nucleus	Cellular component	-
FANCM	57697	Fanconi anemia, complementation group M	nucleic acid phosphodiester bond hydrolysis	Biological process	-
DQX1	165545	DEAQ box RNA-dependent ATPase 1	RNA processing	Biological process	-
SMARCC2	6601	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	positive regulation of transcription, DNA-templated	Biological process	11018012
CPNE6	9362	copine VI (neuronal)	positive regulation of dendrite extension	Biological process	23999003
TNFSF12	8742	tumor necrosis factor (ligand) superfamily, member 12	apoptotic process	Biological process	-
PRPSAP1	5635	phosphoribosyl pyrophosphate synthetase-associated protein 1	nucleobase-containing compound metabolic process	Biological process	8611620
PSEN2	5664	presenilin 2	endopeptidase activity	Molecular function	-
SLC25A31	83447	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31	transporter activity	Molecular function	-
CALM3	808	calmodulin 3 (phosphorylase kinase, delta)	epidermal growth factor receptor signaling pathway	Biological process	-
MRPS15	64960	mitochondrial ribosomal protein S15	structural constituent of ribosome	Molecular function	11279123
PCYOX1	51449	prenylcysteine oxidase 1	plasma membrane	Cellular component	-
PAX6	5080	paired box 6	neural crest cell migration	Biological process	-
PPARG	5468	peroxisome proliferator-activated receptor gamma	negative regulation of collagen biosynthetic process	Biological process	-
PRKAR1B	5575	protein kinase, cAMP-dependent, regulatory, type I, beta	negative regulation of cAMP-dependent protein kinase activity	Biological process	21812984
ATXN2	6311	ataxin 2	polysome	Cellular component	16835262
CPEB4	80315	cytoplasmic polyadenylation element binding protein 4	protein binding	Molecular function	21336257
PRKAR2B	5577	protein kinase, cAMP-dependent, regulatory, type II, beta	activation of phospholipase C activity	Biological process	-
MAP7	9053	microtubule-associated protein 7	establishment or maintenance of cell polarity	Biological process	8408219
CCK	885	cholecystokinin	axonogenesis	Biological process	15152034
OR10V1	390201	olfactory receptor, family 10, subfamily V, member 1	G-protein coupled receptor signaling pathway	Biological process	-
VCAN	1462	versican	glycosaminoglycan metabolic process	Biological process	-
STK11	6794	serine/threonine kinase 11	cell cycle arrest	Biological process	-
ACVR2A	92	activin A receptor, type IIA	inhibin-betaglycan-ActRII complex	Cellular component	10746731
RAB1A	5861	RAB1A, member RAS oncogene family	Golgi apparatus	Cellular component	16791210
MICAL3	57553	microtubule associated monooxygenase, calponin and LIM domain containing 3	actin filament depolymerization	Biological process	-
PIPOX	51268	pipecolic acid oxidase	receptor binding	Molecular function	20178365
POLR2J2	246721	polymerase (RNA) II (DNA directed) polypeptide J2	protein dimerization activity	Molecular function	-
DHX37	57647	DEAH (Asp-Glu-Ala-His) box polypeptide 37	ATP-dependent RNA helicase activity	Molecular function	-
JAK3	3718	Janus kinase 3	positive regulation of dendritic cell apoptotic process	Biological process	-
ZACN	353174	zinc activated ligand-gated ion channel	extracellular ligand-gated ion channel activity	Molecular function	-
NRXN2	9379	neurexin 2	calcium channel regulator activity	Molecular function	-
CDK7	1022	cyclin-dependent kinase 7	perinuclear region of cytoplasm	Cellular component	-
PTPN21	11099	protein tyrosine phosphatase, non-receptor type 21	peptidyl-tyrosine dephosphorylation	Biological process	7519780
ABCG2	9429	ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)	small molecule metabolic process	Biological process	-
CREG1	8804	cellular repressor of E1A-stimulated genes 1	extracellular exosome	Cellular component	23376485
PIAS2	9063	protein inhibitor of activated STAT, 2	post-translational protein modification	Biological process	-
HERC4	26091	HECT and RLD domain containing E3 ubiquitin protein ligase 4	cell differentiation	Biological process	-
CSPG5	10675	chondroitin sulfate proteoglycan 5 (neuroglycan C)	nervous system development	Biological process	12885772
SLC22A6	9356	solute carrier family 22 (organic anion transporter), member 6	inorganic anion exchanger activity	Molecular function	15037815
PTH	5741	parathyroid hormone	positive regulation of bone mineralization	Biological process	17696759
GPCPD1	56261	glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)	phospholipid metabolic process	Biological process	-
PDCD1	5133	programmed cell death 1	positive regulation of T cell apoptotic process	Biological process	25281059
MTOR	2475	mechanistic target of rapamycin (serine/threonine kinase)	positive regulation of lipid biosynthetic process	Biological process	18762023
ADRA1B	147	adrenoceptor alpha 1B	locomotory behavior	Biological process	-
DVL1	1855	dishevelled segment polarity protein 1	neuronal cell body	Cellular component	-
PKDCC	91461	protein kinase domain containing, cytoplasmic	palate development	Biological process	-
IL2RA	3559	interleukin 2 receptor, alpha	positive regulation of T cell differentiation	Biological process	-
CD320	51293	CD320 molecule	membrane	Cellular component	19946888
PREB	10113	prolactin regulatory element binding	regulation of transcription, DNA-templated	Biological process	-
PRDM16	63976	PR domain containing 16	tongue development	Biological process	-
VKORC1	79001	vitamin K epoxide reductase complex, subunit 1	cellular protein metabolic process	Biological process	-
USP9X	8239	ubiquitin specific peptidase 9, X-linked	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological process	-
SNX2	6643	sorting nexin 2	endosome membrane	Cellular component	15673616
HOPX	84525	HOP homeobox	DNA binding	Molecular function	-
SLC37A1	54020	solute carrier family 37 (glucose-6-phosphate transporter), member 1	anion transport	Biological process	-
GPC3	2719	glypican 3	Golgi lumen	Cellular component	-
HSPD1	3329	heat shock 60kDa protein 1 (chaperonin)	extracellular exosome	Cellular component	19056867
MOCS2	4338	molybdenum cofactor synthesis 2	molybdopterin synthase complex	Cellular component	9889283
CUTC	51076	cutC copper transporter	transmembrane transport	Biological process	-
CHRNA1	1134	cholinergic receptor, nicotinic, alpha 1 (muscle)	ion channel activity	Molecular function	6688857
TSPYL2	64061	TSPY-like 2	negative regulation of cell growth	Biological process	11395479
SEL1L	6400	sel-1 suppressor of lin-12-like (C. elegans)	protein binding	Molecular function	18264092
NHEJ1	79840	nonhomologous end-joining factor 1	nonhomologous end joining complex	Cellular component	20383123
SERPINB9	5272	serpin peptidase inhibitor, clade B (ovalbumin), member 9	negative regulation of endopeptidase activity	Biological process	21795594
DRD1	1812	dopamine receptor D1	synapse assembly	Biological process	-
OPRL1	4987	opiate receptor-like 1	integral component of plasma membrane	Cellular component	12568343
MRPS18C	51023	mitochondrial ribosomal protein S18C	mitochondrial translational elongation	Biological process	-
EPHB1	2047	EPH receptor B1	axon guidance	Biological process	-
OR5M10	390167	olfactory receptor, family 5, subfamily M, member 10	olfactory receptor activity	Molecular function	-
PYGM	5837	phosphorylase, glycogen, muscle	small molecule metabolic process	Biological process	-
CHRFAM7A	89832	CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion	ion transmembrane transport	Biological process	-
AKR7A3	22977	aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)	cytosol	Cellular component	-
ALDH9A1	223	aldehyde dehydrogenase 9 family, member A1	kidney development	Biological process	-
ENO4	387712	enolase family member 4	cellular_component	Cellular component	-
RPL29	6159	ribosomal protein L29	structural constituent of ribosome	Molecular function	12962325
MOCS3	27304	molybdenum cofactor synthesis 3	protein adenylyltransferase activity	Molecular function	-
SCGB1A1	7356	secretoglobin, family 1A, member 1 (uteroglobin)	response to fibroblast growth factor	Biological process	-
HIST2H2AA3	8337	histone cluster 2, H2aa3	biological_process	Biological process	-
SORL1	6653	sortilin-related receptor, L(DLR class) A repeats containing	negative regulation of tau-protein kinase activity	Biological process	-
RNF43	54894	ring finger protein 43	protein binding	Molecular function	18313049
FRRS1L	23732	ferric-chelate reductase 1-like	molecular_function	Molecular function	-
BNIP3L	665	BCL2/adenovirus E1B 19kDa interacting protein 3-like	integral component of membrane	Cellular component	-
NR0B1	190	nuclear receptor subfamily 0, group B, member 1	negative regulation of transcription, DNA-templated	Biological process	19651776
CDNF	441549	cerebral dopamine neurotrophic factor	extracellular region	Cellular component	-
FLOT1	10211	flotillin 1	ionotropic glutamate receptor binding	Molecular function	-
PRKD1	5587	protein kinase D1	positive regulation of blood vessel endothelial cell migration	Biological process	18440775
PSMD6	9861	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	proteasome complex	Cellular component	17323924
PGAP2	27315	post-GPI attachment to proteins 2	protein binding	Molecular function	25416956
HSP90B1	7184	heat shock protein 90kDa beta (Grp94), member 1	extracellular exosome	Cellular component	19199708
ING2	3622	inhibitor of growth family, member 2	phosphatidylinositol binding	Molecular function	16893883
TTC21B	79809	tetratricopeptide repeat domain 21B	smoothened signaling pathway	Biological process	-
CDA	978	cytidine deaminase	pyrimidine nucleoside salvage	Biological process	-
SCAP	22937	SREBF chaperone	negative regulation of cholesterol biosynthetic process	Biological process	11969205
STAP1	26228	signal transducing adaptor family member 1	transmembrane receptor protein tyrosine kinase signaling pathway	Biological process	-
TRAF2	7186	TNF receptor-associated factor 2	activation of NF-kappaB-inducing kinase activity	Biological process	15125833
LRRC10	376132	leucine rich repeat containing 10	nucleus	Cellular component	-
ACSM3	6296	acyl-CoA synthetase medium-chain family member 3	regulation of blood pressure	Biological process	7907320
RBSN	64145	rabenosyn, RAB effector	endosome membrane	Cellular component	-
SAP18	10284	Sin3A-associated protein, 18kDa	regulation of gene expression, epigenetic	Biological process	-
SULT6B1	391365	sulfotransferase family, cytosolic, 6B, member 1	metabolic process	Biological process	-
TNC	3371	tenascin C	syndecan binding	Molecular function	8769660
PTPN12	5782	protein tyrosine phosphatase, non-receptor type 12	podosome	Cellular component	-
RPEL1	729020	ribulose-5-phosphate-3-epimerase-like 1	metal ion binding	Molecular function	-
PRSS2	5645	protease, serine, 2 (trypsin 2)	extracellular space	Cellular component	16192646
HLA-E	3133	major histocompatibility complex, class I, E	positive regulation of natural killer cell mediated immunity	Biological process	9754572
LZTR1	8216	leucine-zipper-like transcription regulator 1	regulation of transcription, DNA-templated	Biological process	7633402
CCT3	7203	chaperonin containing TCP1, subunit 3 (gamma)	toxin transport	Biological process	-
CDC73	79577	cell division cycle 73	stem cell maintenance	Biological process	-
TMC4	147798	transmembrane channel-like 4	extracellular exosome	Cellular component	23533145
NFE2	4778	nuclear factor, erythroid 2	sequence-specific DNA binding transcription factor activity	Molecular function	-
RORB	6096	RAR-related orphan receptor B	retinal cone cell development	Biological process	-
PSMB3	5691	proteasome (prosome, macropain) subunit, beta type, 3	nucleoplasm	Cellular component	-
PAK1	5058	p21 protein (Cdc42/Rac)-activated kinase 1	positive regulation of stress fiber assembly	Biological process	11864573
KIFC1	3833	kinesin family member C1	blood coagulation	Biological process	-
CRHBP	1393	corticotropin releasing hormone binding protein	cellular response to cAMP	Biological process	-
HSPA1L	3305	heat shock 70kDa protein 1-like	ubiquitin protein ligase binding	Molecular function	24270810
RQCD1	9125	RCD1 required for cell differentiation1 homolog (S. pombe)	nucleus	Cellular component	-
ABCC6	368	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	ATP binding	Molecular function	-
OR2A2	442361	olfactory receptor, family 2, subfamily A, member 2	G-protein coupled receptor activity	Molecular function	-
NKD1	85407	naked cuticle homolog 1 (Drosophila)	eye photoreceptor cell differentiation	Biological process	15687260
MTF1	4520	metal-regulatory transcription factor 1	protein binding	Molecular function	16189514
TRIM24	8805	tripartite motif containing 24	positive regulation of transcription, DNA-templated	Biological process	-
EIF4G2	1982	eukaryotic translation initiation factor 4 gamma, 2	cell cycle arrest	Biological process	9032289
LIPE	3991	lipase, hormone-sensitive	long-chain fatty acid catabolic process	Biological process	-
LGALS3	3958	lectin, galactoside-binding, soluble, 3	positive regulation of mononuclear cell migration	Biological process	10925302
EFNA5	1946	ephrin-A5	regulation of actin cytoskeleton organization	Biological process	11870224
HNRNPF	3185	heterogeneous nuclear ribonucleoprotein F	single-stranded RNA binding	Molecular function	20526337
ADRA1B	147	adrenoceptor alpha 1B	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure	Biological process	-
PTEN	5728	phosphatase and tensin homolog	rhythmic synaptic transmission	Biological process	-
ATP2A1	487	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	relaxation of skeletal muscle	Biological process	8841193
MFAP5	8076	microfibrillar associated protein 5	extracellular region	Cellular component	-
TP53INP1	94241	tumor protein p53 inducible nuclear protein 1	antioxidant activity	Molecular function	-
CAMKV	79012	CaM kinase-like vesicle-associated	calmodulin binding	Molecular function	-
GOPC	57120	golgi-associated PDZ and coiled-coil motif containing	trans-Golgi network transport vesicle	Cellular component	11384996
AQP3	360	aquaporin 3 (Gill blood group)	glycerol channel activity	Molecular function	17943189
RET	5979	ret proto-oncogene	membrane raft	Cellular component	-
DGKE	8526	diacylglycerol kinase, epsilon 64kDa	intracellular signal transduction	Biological process	-
TRIM10	10107	tripartite motif containing 10	cytoplasm	Cellular component	-
ACTR8	93973	ARP8 actin-related protein 8 homolog (yeast)	transcription, DNA-templated	Biological process	-
HEY1	23462	hes-related family bHLH transcription factor with YRPW motif 1	positive regulation of osteoblast differentiation	Biological process	-
CHRNA3	1136	cholinergic receptor, nicotinic, alpha 3 (neuronal)	nervous system development	Biological process	11450844
UBE2N	7334	ubiquitin-conjugating enzyme E2N	ubiquitin-dependent protein catabolic process	Biological process	-
PLCB3	5331	phospholipase C, beta 3 (phosphatidylinositol-specific)	regulation of systemic arterial blood pressure	Biological process	18468998
CD1D	912	CD1d molecule	cell surface	Cellular component	19124746
VAV2	7410	vav 2 guanine nucleotide exchange factor	cytosol	Cellular component	-
MYOZ1	58529	myozenin 1	myofibril assembly	Biological process	11114196
SLIT2	9353	slit homolog 2 (Drosophila)	proteoglycan binding	Molecular function	11375980
GSR	2936	glutathione reductase	transcription initiation from RNA polymerase II promoter	Biological process	-
HSPG2	3339	heparan sulfate proteoglycan 2	extracellular exosome	Cellular component	19056867
DPP3	10072	dipeptidyl-peptidase 3	dipeptidyl-peptidase activity	Molecular function	10387075
TRIM38	10475	tripartite motif containing 38	protein K48-linked ubiquitination	Biological process	-
PTPRH	5794	protein tyrosine phosphatase, receptor type, H	protein dephosphorylation	Biological process	8294459
GRIA1	2890	glutamate receptor, ionotropic, AMPA 1	cell junction	Cellular component	-
CPEB3	22849	cytoplasmic polyadenylation element binding protein 3	negative regulation of cytoplasmic translational elongation	Biological process	-
PRPS1L1	221823	phosphoribosyl pyrophosphate synthetase 1-like 1	cellular_component	Cellular component	-
KLC2	64837	kinesin light chain 2	membrane	Cellular component	19946888
IRF3	3661	interferon regulatory factor 3	negative regulation of interferon-beta biosynthetic process	Biological process	-
THAP7	80764	THAP domain containing 7	chromosome	Cellular component	-
POU2F1	5451	POU class 2 homeobox 1	negative regulation of transcription, DNA-templated	Biological process	11891224
POLR2C	5432	polymerase (RNA) II (DNA directed) polypeptide C, 33kDa	RNA polymerase II activity	Molecular function	-
CDC42	998	cell division cycle 42	small GTPase mediated signal transduction	Biological process	-
PSEN1	5663	presenilin 1	Cajal-Retzius cell differentiation	Biological process	-
HEY2	23493	hes-related family bHLH transcription factor with YRPW motif 2	cardiac muscle hypertrophy in response to stress	Biological process	-
RPS3A	6189	ribosomal protein S3A	cellular protein metabolic process	Biological process	-
POLR2M	81488	polymerase (RNA) II (DNA directed) polypeptide M	RNA biosynthetic process	Biological process	-
ZNF154	7710	zinc finger protein 154	nucleus	Cellular component	7557990
CALM2	805	calmodulin 2 (phosphorylase kinase, delta)	thioesterase binding	Molecular function	16127172
NOX5	79400	NADPH oxidase, EF-hand calcium binding domain 5	cell proliferation	Biological process	11483596
PDE11A	50940	phosphodiesterase 11A	blood coagulation	Biological process	-
SLC40A1	30061	solute carrier family 40 (iron-regulated transporter), member 1	anatomical structure morphogenesis	Biological process	10693807
PPAP2B	8613	phosphatidic acid phosphatase type 2B	adherens junction	Cellular component	20123964
HIPK2	28996	homeodomain interacting protein kinase 2	smoothened signaling pathway	Biological process	-
APOA5	116519	apolipoprotein A-V	positive regulation of lipoprotein lipase activity	Biological process	15178420
CXXC5	51523	CXXC finger protein 5	transcription, DNA-templated	Biological process	-
CATSPER1	117144	cation channel, sperm associated 1	sperm-egg recognition	Biological process	-
SHH	6469	sonic hedgehog	morphogen activity	Molecular function	8647801
PDE1B	5153	phosphodiesterase 1B, calmodulin-dependent	activation of phospholipase C activity	Biological process	-
OR4A47	403253	olfactory receptor, family 4, subfamily A, member 47	olfactory receptor activity	Molecular function	-
GRB10	2887	growth factor receptor-bound protein 10	protein binding	Molecular function	15060076
CTNNA1	1495	catenin (cadherin-associated protein), alpha 1, 102kDa	apical junction assembly	Biological process	9700171
MGEA5	10724	meningioma expressed antigen 5 (hyaluronidase)	positive regulation of insulin secretion	Biological process	-
CNOT11	55571	CCR4-NOT transcription complex, subunit 11	cell proliferation	Biological process	10497265
AMBRA1	55626	autophagy/beclin-1 regulator 1	cytosol	Cellular component	21753002
PVRL1	5818	poliovirus receptor-related 1 (herpesvirus entry mediator C)	coreceptor activity	Molecular function	9616127
CAV3	859	caveolin 3	positive regulation of cytosolic calcium ion concentration	Biological process	-
CD34	947	CD34 molecule	carbohydrate binding	Molecular function	15249540
A1CF	29974	APOBEC1 complementation factor	protein binding	Molecular function	10669759
ARSB	411	arylsulfatase B	metal ion binding	Molecular function	-
NCR3LG1	374383	natural killer cell cytotoxicity receptor 3 ligand 1	plasma membrane	Cellular component	-
CTU2	348180	cytosolic thiouridylase subunit 2 homolog (S. pombe)	cytoplasm	Cellular component	-
PARP1	142	poly (ADP-ribose) polymerase 1	protein ADP-ribosylation	Biological process	17396150
ABCA4	24	ATP-binding cassette, sub-family A (ABC1), member 4	photoreceptor disc membrane	Cellular component	-
NOS1	4842	nitric oxide synthase 1 (neuronal)	dendritic spine	Cellular component	-
NBAS	51594	neuroblastoma amplified sequence	retrograde vesicle-mediated transport, Golgi to ER	Biological process	-
AGTR1	185	angiotensin II receptor, type 1	positive regulation of macrophage derived foam cell differentiation	Biological process	18971559
SLC6A3	6531	solute carrier family 6 (neurotransmitter transporter), member 3	lactation	Biological process	-
LINC00518	221718	long intergenic non-protein coding RNA 518	protein binding	Molecular function	25416956
NSMF	26012	NMDA receptor synaptonuclear signaling and neuronal migration factor	nuclear euchromatin	Cellular component	-
CNIH3	149111	cornichon family AMPA receptor auxiliary protein 3	postsynaptic membrane	Cellular component	-
GNB1	2782	guanine nucleotide binding protein (G protein), beta polypeptide 1	adenylate cyclase-activating dopamine receptor signaling pathway	Biological process	-
SASH1	23328	SAM and SH3 domain containing 1	membrane	Cellular component	-
CBX3	11335	chromobox homolog 3	protein binding	Molecular function	10330177
TGFBR1	7046	transforming growth factor, beta receptor 1	positive regulation of pathway-restricted SMAD protein phosphorylation	Biological process	9311995
ATP8B1	5205	ATPase, aminophospholipid transporter, class I, type 8B, member 1	sensory perception of sound	Biological process	-
F5	2153	coagulation factor V (proaccelerin, labile factor)	extracellular region	Cellular component	-
NCOR1	9611	nuclear receptor corepressor 1	regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter	Biological process	19955185
OR2T12	127064	olfactory receptor, family 2, subfamily T, member 12	sensory perception of smell	Biological process	-
HOXD13	3239	homeobox D13	morphogenesis of an epithelial fold	Biological process	-
SSH3	54961	slingshot protein phosphatase 3	nucleus	Cellular component	-
TFPT	29844	TCF3 (E2A) fusion partner (in childhood Leukemia)	cytoplasm	Cellular component	-
IL33	90865	interleukin 33	positive regulation of interleukin-13 production	Biological process	-
POLA1	5422	polymerase (DNA directed), alpha 1, catalytic subunit	nuclear matrix	Cellular component	1903085
APLP1	333	amyloid beta (A4) precursor-like protein 1	alpha-2C adrenergic receptor binding	Molecular function	16531006
TH	7054	tyrosine hydroxylase	ferric iron binding	Molecular function	-
CCDC155	147872	coiled-coil domain containing 155	lateral element	Cellular component	-
B9D2	80776	B9 protein domain 2	membrane	Cellular component	-
ATP1A3	478	ATPase, Na+/K+ transporting, alpha 3 polypeptide	myelin sheath	Cellular component	-
MBLAC2	153364	metallo-beta-lactamase domain containing 2	extracellular exosome	Cellular component	20458337
TOPORS	10210	topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase	midbody	Cellular component	21159800
SLC23A2	9962	solute carrier family 23 (ascorbic acid transporter), member 2	sodium-dependent L-ascorbate transmembrane transporter activity	Molecular function	10631088
ATP1B3	483	ATPase, Na+/K+ transporting, beta 3 polypeptide	ATPase binding	Molecular function	10636900
SETDB2	83852	SET domain, bifurcated 2	nucleus	Cellular component	20404330
SLC4A10	57282	solute carrier family 4, sodium bicarbonate transporter, member 10	inorganic anion exchanger activity	Molecular function	-
PGA3	643834	pepsinogen 3, group I (pepsinogen A)	aspartic-type endopeptidase activity	Molecular function	-
OBFC1	79991	oligonucleotide/oligosaccharide-binding fold containing 1	nuclear chromosome, telomeric region	Cellular component	19648609
PHC1	1911	polyhomeotic homolog 1 (Drosophila)	multicellular organismal development	Biological process	-
CD36	948	CD36 molecule (thrombospondin receptor)	cellular response to lipoteichoic acid	Biological process	-
ESR1	2099	estrogen receptor 1	nucleoplasm	Cellular component	-
ROCK2	9475	Rho-associated, coiled-coil containing protein kinase 2	Rho GTPase binding	Molecular function	-
CALR3	125972	calreticulin 3	spermatogenesis	Biological process	-
OPRD1	4985	opioid receptor, delta 1	integral component of plasma membrane	Cellular component	7808419
FLOT1	10211	flotillin 1	protein kinase C signaling	Biological process	21399631
SUCNR1	56670	succinate receptor 1	G-protein coupled receptor activity	Molecular function	-
CHRNA9	55584	cholinergic receptor, nicotinic, alpha 9 (neuronal)	synaptic transmission	Biological process	-
B3GAT3	26229	beta-1,3-glucuronyltransferase 3	metal ion binding	Molecular function	-
XBP1	7494	X-box binding protein 1	sequence-specific DNA binding transcription factor activity	Molecular function	1903538
TGFB1I1	7041	transforming growth factor beta 1 induced transcript 1	intracellular	Cellular component	10075738
DHH	50846	desert hedgehog	plasma membrane	Cellular component	-
MNAT1	4331	MNAT CDK-activating kinase assembly factor 1	transcription initiation from RNA polymerase I promoter	Biological process	-
APC	324	adenomatous polyposis coli	positive regulation of apoptotic process	Biological process	17227893
GRIK5	2901	glutamate receptor, ionotropic, kainate 5	extracellular-glutamate-gated ion channel activity	Molecular function	-
BRMS1L	84312	breast cancer metastasis-suppressor 1-like	histone deacetylation	Biological process	-
RNPC3	55599	RNA-binding region (RNP1, RRM) containing 3	U12-type spliceosomal complex	Cellular component	15146077
VPS28	51160	vacuolar protein sorting 28 homolog (S. cerevisiae)	viral process	Biological process	-
CHST10	9486	carbohydrate sulfotransferase 10	membrane	Cellular component	9478973
RAPGEF1	2889	Rap guanine nucleotide exchange factor (GEF) 1	regulation of cell junction assembly	Biological process	21840392
SDC4	6385	syndecan 4	positive regulation of exosomal secretion	Biological process	22660413
HSPA2	3306	heat shock 70kDa protein 2	membrane	Cellular component	19946888
GPAA1	8733	glycosylphosphatidylinositol anchor attachment 1	attachment of GPI anchor to protein	Biological process	11483512
UBE2N	7334	ubiquitin-conjugating enzyme E2N	ubiquitin binding	Molecular function	16122702
RANBP2	5903	RAN binding protein 2	cellular protein metabolic process	Biological process	-
NLRP10	338322	NLR family, pyrin domain containing 10	positive regulation of T-helper 1 type immune response	Biological process	-
APEX1	328	APEX nuclease (multifunctional DNA repair enzyme) 1	transcription, DNA-templated	Biological process	-
EDNRA	1909	endothelin receptor type A	negative regulation of cAMP biosynthetic process	Biological process	-
IQSEC3	440073	IQ motif and Sec7 domain 3	trans-Golgi network	Cellular component	-
NUP98	4928	nucleoporin 98kDa	nuclear inclusion body	Cellular component	11839768
ITGA3	3675	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	memory	Biological process	-
EIF3E	3646	eukaryotic translation initiation factor 3, subunit E	negative regulation of translational initiation	Biological process	10504338
CAPN10	11132	calpain 10	positive regulation of intracellular transport	Biological process	12974673
CPTP	80772	ceramide-1-phosphate transfer protein	endosome membrane	Cellular component	-
USP4	7375	ubiquitin specific peptidase 4 (proto-oncogene)	protein binding	Molecular function	11461834
SLC9A1	6548	solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1	cardiac muscle cell contraction	Biological process	-
CCL23	6368	chemokine (C-C motif) ligand 23	cell	Cellular component	9886417
PIGR	5284	polymeric immunoglobulin receptor	receptor clustering	Biological process	22022593
EDN1	1906	endothelin 1	superoxide anion generation	Biological process	-
HRNR	388697	hornerin	nucleus	Cellular component	21630459
AP4E1	23431	adaptor-related protein complex 4, epsilon 1 subunit	endosome lumen	Cellular component	-
SMARCC2	6601	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	protein complex	Cellular component	16217013
ERH	2079	enhancer of rudimentary homolog (Drosophila)	cell cycle	Biological process	-
AHNAK2	113146	AHNAK nucleoprotein 2	T-tubule	Cellular component	17185750
A4GALT	53947	alpha 1,4-galactosyltransferase	plasma membrane organization	Biological process	10747952
SYDE2	84144	synapse defective 1, Rho GTPase, homolog 2 (C. elegans)	activation of GTPase activity	Biological process	-
APOE	348	apolipoprotein E	cholesterol catabolic process	Biological process	-
MAP3K15	389840	mitogen-activated protein kinase kinase kinase 15	intracellular	Cellular component	-
NCL	4691	nucleolin	angiogenesis	Biological process	16403913
BTG2	7832	BTG family, member 2	protein binding	Molecular function	11136725
BAK1	578	BCL2-antagonist/killer 1	B cell apoptotic process	Biological process	-
MELK	9833	maternal embryonic leucine zipper kinase	cytoplasm	Cellular component	-
STX12	23673	syntaxin 12	cholesterol efflux	Biological process	15469992
DRD3	1814	dopamine receptor D3	acid secretion	Biological process	-
SLC9A5	6553	solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5	sodium:proton antiporter activity	Molecular function	-
APBA3	9546	amyloid beta (A4) precursor protein-binding, family A, member 3	enzyme inhibitor activity	Molecular function	19726677
CYP11B1	1584	cytochrome P450, family 11, subfamily B, polypeptide 1	oxidation-reduction process	Biological process	-
IL10RA	3587	interleukin 10 receptor, alpha	plasma membrane	Cellular component	-
ZNF775	285971	zinc finger protein 775	nucleus	Cellular component	-
PFKP	5214	phosphofructokinase, platelet	small molecule metabolic process	Biological process	-
CHRND	1144	cholinergic receptor, nicotinic, delta (muscle)	acetylcholine-gated channel complex	Cellular component	-
THOC1	9984	THO complex 1	nuclear matrix	Cellular component	-
SKP2	6502	S-phase kinase-associated protein 2, E3 ubiquitin protein ligase	cytoplasm	Cellular component	-
LGR4	55366	leucine-rich repeat containing G protein-coupled receptor 4	bone mineralization	Biological process	-
HIST1H3F	8968	histone cluster 1, H3f	DNA replication-dependent nucleosome assembly	Biological process	14718166
ZNF662	389114	zinc finger protein 662	regulation of transcription from RNA polymerase II promoter	Biological process	-
SSX1	6756	synovial sarcoma, X breakpoint 1	nucleus	Cellular component	-
MAT2B	27430	methionine adenosyltransferase II, beta	methionine adenosyltransferase complex	Cellular component	10644686
CDK2	1017	cyclin-dependent kinase 2	histone phosphorylation	Biological process	8692841
MTERF2	80298	mitochondrial transcription termination factor 2	mitochondrial matrix	Cellular component	-
INSL3	3640	insulin-like 3 (Leydig cell)	G-protein coupled receptor binding	Molecular function	-
ARRB1	408	arrestin, beta 1	insulin-like growth factor receptor binding	Molecular function	15878855
PSMD1	5707	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	Biological process	-
VDR	7421	vitamin D (1,25- dihydroxyvitamin D3) receptor	signal transduction	Biological process	2849209
TCEAL6	158931	transcription elongation factor A (SII)-like 6	transcription, DNA-templated	Biological process	-
GLRA1	2741	glycine receptor, alpha 1	neuropeptide signaling pathway	Biological process	2155780
BMP7	655	bone morphogenetic protein 7	positive regulation of dendrite development	Biological process	11580864
MAP3K12	7786	mitogen-activated protein kinase kinase kinase 12	protein phosphorylation	Biological process	-
UBE2T	29089	ubiquitin-conjugating enzyme E2T	chromatin binding	Molecular function	17938197
EFHC1	114327	EF-hand domain (C-terminal) containing 1	cerebral cortex cell migration	Biological process	22926142
PPP2R3C	55012	protein phosphatase 2, regulatory subunit B'', gamma	centrosome	Cellular component	21399614
PARK2	5071	parkin RBR E3 ubiquitin protein ligase	adult locomotory behavior	Biological process	-
USP32	84669	ubiquitin specific peptidase 32	protein binding	Molecular function	24705354
OBSCN	84033	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	small GTPase mediated signal transduction	Biological process	-
SUPV3L1	6832	suppressor of var1, 3-like 1 (S. cerevisiae)	DNA duplex unwinding	Biological process	12466530
EFNA2	1943	ephrin-A2	ephrin receptor signaling pathway	Biological process	-
EGFR	1956	epidermal growth factor receptor	positive regulation of epithelial cell proliferation	Biological process	10572067
DNASE1	1773	deoxyribonuclease I	nucleus	Cellular component	-
CAPN6	827	calpain 6	microtubule bundle formation	Biological process	-
USP33	23032	ubiquitin specific peptidase 33	G-protein coupled receptor binding	Molecular function	19424180
GIP	2695	gastric inhibitory polypeptide	protein binding	Molecular function	25416956
TMEM151A	256472	transmembrane protein 151A	integral component of membrane	Cellular component	-
AP3D1	8943	adaptor-related protein complex 3, delta 1 subunit	synaptic vesicle membrane organization	Biological process	-
RPLP0	6175	ribosomal protein, large, P0	ribosome biogenesis	Biological process	-
SLC9A3R1	9368	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1	growth factor receptor binding	Molecular function	17242191
TKT	7086	transketolase	carbohydrate metabolic process	Biological process	-
PIK3R2	5296	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	cellular response to insulin stimulus	Biological process	-
TNP1	7141	transition protein 1 (during histone to protamine replacement)	single strand break repair	Biological process	12743712
TFAP2B	7021	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	positive regulation of neuron apoptotic process	Biological process	20607706
ACACB	32	acetyl-CoA carboxylase beta	energy reserve metabolic process	Biological process	-
CCL21	6366	chemokine (C-C motif) ligand 21	positive regulation of pseudopodium assembly	Biological process	11242036
RABL6	55684	RAB, member RAS oncogene family-like 6	nucleolus	Cellular component	-
TUBB3	10381	tubulin, beta 3 class III	extracellular exosome	Cellular component	23533145
ARHGEF2	9181	Rho/Rac guanine nucleotide exchange factor (GEF) 2	positive regulation of tumor necrosis factor production	Biological process	21887730
MIP	4284	major intrinsic protein of lens fiber	transmembrane transport	Biological process	-
TFCP2L1	29842	transcription factor CP2-like 1	salivary gland development	Biological process	-
KCNK10	54207	potassium channel, two pore domain subfamily K, member 10	signal transduction	Biological process	10880510
MOSPD1	56180	motile sperm domain containing 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
VPS4B	9525	vacuolar protein sorting 4 homolog B (S. cerevisiae)	endosome membrane	Cellular component	16757520
GZMM	3004	granzyme M (lymphocyte met-ase 1)	cytolysis	Biological process	-
NUP205	23165	nucleoporin 205kDa	nuclear pore	Cellular component	9348540
FASLG	356	Fas ligand (TNF superfamily, member 6)	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	-
CD8B	926	CD8b molecule	protein binding	Molecular function	2493728
IFNA7	3444	interferon, alpha 7	innate immune response	Biological process	-
HMGN1	3150	high mobility group nucleosome binding domain 1	regulation of transcription from RNA polymerase II promoter	Biological process	-
SYNC	81493	syncoilin, intermediate filament protein	intermediate filament-based process	Biological process	-
DPP9	91039	dipeptidyl-peptidase 9	nucleus	Cellular component	-
PTGES2	80142	prostaglandin E synthase 2	mitochondrion	Cellular component	-
CACNA1C	775	calcium channel, voltage-dependent, L type, alpha 1C subunit	neuronal cell body	Cellular component	-
HSD17B13	345275	hydroxysteroid (17-beta) dehydrogenase 13	cellular_component	Cellular component	-
SMC1A	8243	structural maintenance of chromosomes 1A	mitotic cell cycle checkpoint	Biological process	11877377
CAMK2D	817	calcium/calmodulin-dependent protein kinase II delta	endoplasmic reticulum calcium ion homeostasis	Biological process	-
MGP	4256	matrix Gla protein	protein binding	Molecular function	15607035
MED1	5469	mediator complex subunit 1	RNA polymerase II transcription cofactor activity	Molecular function	10198638
PNISR	25957	PNN-interacting serine/arginine-rich protein	cytoplasm	Cellular component	-
HDAC2	3066	histone deacetylase 2	negative regulation of MHC class II biosynthetic process	Biological process	19041327
INSR	3643	insulin receptor	positive regulation of mitotic nuclear division	Biological process	11500939
ODC1	4953	ornithine decarboxylase 1	protein homodimerization activity	Molecular function	-
SIX4	51804	SIX homeobox 4	regulation of branch elongation involved in ureteric bud branching	Biological process	-
XRN1	54464	5'-3' exoribonuclease 1	nucleus	Cellular component	17545563
ADAM10	102	ADAM metallopeptidase domain 10	ephrin receptor signaling pathway	Biological process	-
RAP1A	5906	RAP1A, member of RAS oncogene family	cellular response to cAMP	Biological process	21840392
RAB40C	57799	RAB40C, member RAS oncogene family	protein secretion	Biological process	-
ZNF222	7673	zinc finger protein 222	DNA binding	Molecular function	-
NUP205	23165	nucleoporin 205kDa	protein sumoylation	Biological process	-
HOGA1	112817	4-hydroxy-2-oxoglutarate aldolase 1	protein homodimerization activity	Molecular function	21998747
GAS2L3	283431	growth arrest-specific 2 like 3	actin cytoskeleton	Cellular component	21561867
JUN	3725	jun proto-oncogene	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	-
GPR33	2856	G protein-coupled receptor 33 (gene/pseudogene)	integral component of membrane	Cellular component	-
LIPN	643418	lipase, family member N	extracellular region	Cellular component	-
CLN3	1201	ceroid-lipofuscinosis, neuronal 3	lysosomal membrane	Cellular component	17897319
ABCD1	215	ATP-binding cassette, sub-family D (ALD), member 1	fatty acid beta-oxidation using acyl-CoA oxidase	Biological process	-
SH3BP4	23677	SH3-domain binding protein 4	negative regulation of cell growth	Biological process	22575674
HGS	9146	hepatocyte growth factor-regulated tyrosine kinase substrate	cytosol	Cellular component	-
HBEGF	1839	heparin-binding EGF-like growth factor	plasma membrane	Cellular component	-
RCVRN	5957	recoverin	positive regulation of guanylate cyclase activity	Biological process	1672047
PPA2	27068	pyrophosphatase (inorganic) 2	dephosphorylation	Biological process	-
CXCR3	2833	chemokine (C-X-C motif) receptor 3	integral component of plasma membrane	Cellular component	9064356
SHMT2	6472	serine hydroxymethyltransferase 2 (mitochondrial)	protein binding	Molecular function	25416956
CYBRD1	79901	cytochrome b reductase 1	ferric-chelate reductase activity	Molecular function	14499595
KSR2	283455	kinase suppressor of ras 2	membrane	Cellular component	-
CEP97	79598	centrosomal protein 97kDa	cytoplasm	Cellular component	-
PIPOX	51268	pipecolic acid oxidase	L-pipecolate oxidase activity	Molecular function	10772957
IL27	246778	interleukin 27	extracellular space	Cellular component	-
EXOSC10	5394	exosome component 10	nucleotide binding	Molecular function	-
OR4F21	441308	olfactory receptor, family 4, subfamily F, member 21	detection of chemical stimulus involved in sensory perception	Biological process	-
KAT6A	7994	K(lysine) acetyltransferase 6A	protein binding	Molecular function	11742995
MUC1	4582	mucin 1, cell surface associated	regulation of transcription from RNA polymerase II promoter in response to stress	Biological process	15710329
CAPN6	827	calpain 6	microtubule binding	Molecular function	-
MMP17	4326	matrix metallopeptidase 17 (membrane-inserted)	anchored component of membrane	Cellular component	-
KCNC4	3749	potassium channel, voltage gated Shaw related subfamily C, member 4	voltage-gated potassium channel activity	Molecular function	1920536
INPP1	3628	inositol polyphosphate-1-phosphatase	phosphate-containing compound metabolic process	Biological process	8390685
TUBA4A	7277	tubulin, alpha 4a	G2/M transition of mitotic cell cycle	Biological process	-
COL4A3BP	10087	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein	small molecule metabolic process	Biological process	-
HSD17B7	51478	hydroxysteroid (17-beta) dehydrogenase 7	estradiol 17-beta-dehydrogenase activity	Molecular function	-
FOXC1	2296	forkhead box C1	maintenance of lens transparency	Biological process	-
CASP8	841	caspase 8, apoptosis-related cysteine peptidase	response to tumor necrosis factor	Biological process	10521396
PRKAR1A	5573	protein kinase, cAMP-dependent, regulatory, type I, alpha	cAMP binding	Molecular function	-
SPAST	6683	spastin	cytoplasmic microtubule organization	Biological process	-
CORO6	84940	coronin 6	protein binding	Molecular function	25416956
SFN	2810	stratifin	gene expression	Biological process	-
ST3GAL1	6482	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	post-translational protein modification	Biological process	-
CYTH1	9267	cytohesin 1	establishment of epithelial cell polarity	Biological process	-
PLK3	1263	polo-like kinase 3	G1/S transition of mitotic cell cycle	Biological process	17264206
SMAP1	60682	small ArfGAP 1	clathrin binding	Molecular function	-
PAOX	196743	polyamine oxidase (exo-N4-amino)	receptor binding	Molecular function	20178365
IGSF9	57549	immunoglobulin superfamily, member 9	homophilic cell adhesion via plasma membrane adhesion molecules	Biological process	-
MSTN	2660	myostatin	response to heat	Biological process	-
C2orf71	388939	chromosome 2 open reading frame 71	primary cilium	Cellular component	20398886
EDNRB	1910	endothelin receptor type B	regulation of fever generation	Biological process	-
PIK3CB	5291	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta	phospholipid metabolic process	Biological process	-
PPM1F	9647	protein phosphatase, Mg2+/Mn2+ dependent, 1F	protein complex	Cellular component	11864573
ITGA6	3655	integrin, alpha 6	laminin binding	Molecular function	-
NPR1	4881	natriuretic peptide receptor 1	hormone binding	Molecular function	12547834
ST3GAL5	8869	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	protein N-linked glycosylation via asparagine	Biological process	-
NIPA1	123606	non imprinted in Prader-Willi/Angelman syndrome 1	early endosome	Cellular component	-
RSRC2	65117	arginine/serine-rich coiled-coil 2	protein binding	Molecular function	25416956
GABARAPL1	23710	GABA(A) receptor-associated protein like 1	nucleophagy	Biological process	-
HIST1H4I	8294	histone cluster 1, H4i	poly(A) RNA binding	Molecular function	22658674
BIN1	274	bridging integrator 1	actin cytoskeleton	Cellular component	9182667
DTX2	113878	deltex 2, E3 ubiquitin ligase	cytoplasm	Cellular component	-
NDFIP2	54602	Nedd4 family interacting protein 2	integral component of membrane	Cellular component	-
MYO1F	4542	myosin IF	unconventional myosin complex	Cellular component	9119401
ADRB3	155	adrenoceptor beta 3	positive regulation of MAPK cascade	Biological process	15123695
FRS2	10818	fibroblast growth factor receptor substrate 2	regulation of epithelial cell proliferation	Biological process	-
MB21D1	115004	Mab-21 domain containing 1	activation of innate immune response	Biological process	23258413
SLC38A5	92745	solute carrier family 38, member 5	transmembrane transport	Biological process	-
SMARCA4	6597	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	cell morphogenesis	Biological process	-
KCNG2	26251	potassium channel, voltage gated modifier subfamily G, member 2	extracellular exosome	Cellular component	19056867
TEK	7010	TEK tyrosine kinase, endothelial	positive regulation of protein kinase B signaling	Biological process	18425120
NADK	65220	NAD kinase	NAD metabolic process	Biological process	-
SRI	6717	sorcin	repressing transcription factor binding	Molecular function	-
FCAR	2204	Fc fragment of IgA receptor	immune response	Biological process	10835685
ERC2	26059	ELKS/RAB6-interacting/CAST family member 2	cytoplasm	Cellular component	-
SOX8	30812	SRY (sex determining region Y)-box 8	in utero embryonic development	Biological process	-
RAPGEF1	2889	Rap guanine nucleotide exchange factor (GEF) 1	single organismal cell-cell adhesion	Biological process	-
CAV1	857	caveolin 1, caveolae protein, 22kDa	protein localization to plasma membrane raft	Biological process	-
SOD1	6647	superoxide dismutase 1, soluble	response to drug	Biological process	-
TCF7	6932	transcription factor 7 (T-cell specific, HMG-box)	regulation of cell proliferation	Biological process	-
EIF4EBP1	1978	eukaryotic translation initiation factor 4E binding protein 1	cytoplasm	Cellular component	-
RBM12	10137	RNA binding motif protein 12	poly(A) RNA binding	Molecular function	22658674
TMEM201	199953	transmembrane protein 201	fibroblast migration	Biological process	-
ITGB1	3688	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	virus receptor activity	Molecular function	-
ADAP2	55803	ArfGAP with dual PH domains 2	phosphatidylinositol-3,4-bisphosphate binding	Molecular function	12018390
ATXN7	6314	ataxin 7	nucleus organization	Biological process	10441328
MMAB	326625	methylmalonic aciduria (cobalamin deficiency) cblB type	vitamin metabolic process	Biological process	-
LCTL	197021	lactase-like	hydrolase activity, hydrolyzing O-glycosyl compounds	Molecular function	-
GUCY1A2	2977	guanylate cyclase 1, soluble, alpha 2	blood coagulation	Biological process	-
FDX1L	112812	ferredoxin 1-like	xenobiotic metabolic process	Biological process	-
TECR	9524	trans-2,3-enoyl-CoA reductase	oxidoreductase activity, acting on the CH-CH group of donors	Molecular function	-
EIF2AK4	440275	eukaryotic translation initiation factor 2 alpha kinase 4	cellular response to starvation	Biological process	-
UCN	7349	urocortin	pancreatic juice secretion	Biological process	-
WT1	7490	Wilms tumor 1	negative regulation of transcription, DNA-templated	Biological process	12802290
TRAM1L1	133022	translocation associated membrane protein 1-like 1	integral component of membrane	Cellular component	-
SEPP1	6414	selenoprotein P, plasma, 1	selenium binding	Molecular function	-
ECHDC3	79746	enoyl CoA hydratase domain containing 3	metabolic process	Biological process	-
AKAP14	158798	A kinase (PRKA) anchor protein 14	spermatogenesis	Biological process	-
NMNAT1	64802	nicotinamide nucleotide adenylyltransferase 1	vitamin metabolic process	Biological process	-
FGFR2	2263	fibroblast growth factor receptor 2	positive regulation of cell cycle	Biological process	-
HLX	3142	H2.0-like homeobox	positive regulation of T-helper 1 cell differentiation	Biological process	-
SMURF1	57154	SMAD specific E3 ubiquitin protein ligase 1	ubiquitin-protein transferase activity	Molecular function	10458166
UBR2	23304	ubiquitin protein ligase E3 component n-recognin 2	ubiquitin protein ligase activity	Molecular function	-
PACSIN1	29993	protein kinase C and casein kinase substrate in neurons 1	cytoskeleton organization	Biological process	-
VEGFA	7422	vascular endothelial growth factor A	positive regulation of protein autophosphorylation	Biological process	17470632
LRP4	4038	low density lipoprotein receptor-related protein 4	BMP signaling pathway	Biological process	-
MAP3K12	7786	mitogen-activated protein kinase kinase kinase 12	axon	Cellular component	-
RCVRN	5957	recoverin	rhodopsin mediated signaling pathway	Biological process	-
DDR1	780	discoidin domain receptor tyrosine kinase 1	branching involved in mammary gland duct morphogenesis	Biological process	-
PHKG1	5260	phosphorylase kinase, gamma 1 (muscle)	glucose metabolic process	Biological process	-
FAT1	2195	FAT atypical cadherin 1	focal adhesion	Cellular component	21423176
FIBIN	387758	fin bud initiation factor homolog (zebrafish)	extracellular region	Cellular component	-
MYOC	4653	myocilin, trabecular meshwork inducible glucocorticoid response	myelination in peripheral nervous system	Biological process	-
TNFSF9	8744	tumor necrosis factor (ligand) superfamily, member 9	cell proliferation	Biological process	8088337
IRAK1	3654	interleukin-1 receptor-associated kinase 1	aging	Biological process	-
CCAR2	57805	cell cycle and apoptosis regulator 2	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	Biological process	23398316
PPA1	5464	pyrophosphatase (inorganic) 1	inorganic diphosphatase activity	Molecular function	-
ENC1	8507	ectodermal-neural cortex 1 (with BTB domain)	nervous system development	Biological process	9566959
PHB2	11331	prohibitin 2	protein C-terminus binding	Molecular function	19906925
ADH7	131	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	cytosol	Cellular component	-
MYH10	4628	myosin, heavy chain 10, non-muscle	microfilament motor activity	Molecular function	15845534
PHYHIPL	84457	phytanoyl-CoA 2-hydroxylase interacting protein-like	protein binding	Molecular function	25416956
BFAR	51283	bifunctional apoptosis regulator	membrane	Cellular component	10716992
GARS	2617	glycyl-tRNA synthetase	protein dimerization activity	Molecular function	17544401
ZNF132	7691	zinc finger protein 132	sequence-specific DNA binding transcription factor activity	Molecular function	7557990
MEF2C	4208	myocyte enhancer factor 2C	muscle cell differentiation	Biological process	-
F2R	2149	coagulation factor II (thrombin) receptor	negative regulation of glomerular filtration	Biological process	-
RBM26	64062	RNA binding motif protein 26	protein binding	Molecular function	17577209
CASP14	23581	caspase 14, apoptosis-related cysteine peptidase	nucleus	Cellular component	23377137
IFNA10	3446	interferon, alpha 10	T cell activation involved in immune response	Biological process	-
TRIM54	57159	tripartite motif containing 54	microtubule binding	Molecular function	-
WNT7B	7477	wingless-type MMTV integration site family, member 7B	response to glucocorticoid	Biological process	-
CHRNB4	1143	cholinergic receptor, nicotinic, beta 4 (neuronal)	ligand-gated ion channel activity	Molecular function	20438829
PIPOX	51268	pipecolic acid oxidase	tetrahydrofolate metabolic process	Biological process	-
CDKN3	1033	cyclin-dependent kinase inhibitor 3	negative regulation of cell proliferation	Biological process	8242750
UBA52	7311	ubiquitin A-52 residue ribosomal protein fusion product 1	DNA repair	Biological process	-
SLC11A2	4891	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2	ferrous iron transport	Biological process	12734107
THEM5	284486	thioesterase superfamily member 5	palmitoyl-CoA hydrolase activity	Molecular function	22586271
GRIN2A	2903	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	sensory perception of pain	Biological process	-
AKR1C1	1645	aldo-keto reductase family 1, member C1	ketosteroid monooxygenase activity	Molecular function	21232532
HRG	3273	histidine-rich glycoprotein	immunoglobulin binding	Molecular function	10514432
NEUROD6	63974	neuronal differentiation 6	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	-
CALCRL	10203	calcitonin receptor-like	integral component of plasma membrane	Cellular component	7818539
CACNG8	59283	calcium channel, voltage-dependent, gamma subunit 8	postsynaptic membrane	Cellular component	-
KLF2	10365	Kruppel-like factor 2	cellular response to laminar fluid shear stress	Biological process	23043106
PDCD10	11235	programmed cell death 10	negative regulation of gene expression	Biological process	23388056
MRPL38	64978	mitochondrial ribosomal protein L38	mitochondrial inner membrane	Cellular component	-
DRD4	1815	dopamine receptor D4	synaptic transmission	Biological process	-
KPNA5	3841	karyopherin alpha 5 (importin alpha 6)	cytosol	Cellular component	-
TAF11	6882	TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa	nucleoplasm	Cellular component	-
MTOR	2475	mechanistic target of rapamycin (serine/threonine kinase)	regulation of fatty acid beta-oxidation	Biological process	-
GSTA2	2939	glutathione S-transferase alpha 2	glutathione transferase activity	Molecular function	-
B3GAT3	26229	beta-1,3-glucuronyltransferase 3	cis-Golgi network	Cellular component	21763480
FGG	2266	fibrinogen gamma chain	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	Biological process	10903502
HJURP	55355	Holliday junction recognition protein	cell cycle	Biological process	-
EXOC8	149371	exocyst complex component 8	exocyst assembly	Biological process	-
CYP4F3	4051	cytochrome P450, family 4, subfamily F, polypeptide 3	endoplasmic reticulum membrane	Cellular component	-
PAK1	5058	p21 protein (Cdc42/Rac)-activated kinase 1	protein kinase binding	Molecular function	-
PPP1CA	5499	protein phosphatase 1, catalytic subunit, alpha isozyme	nucleoplasm	Cellular component	-
URGCP	55665	upregulator of cell proliferation	cell cycle	Biological process	-
HLTF	6596	helicase-like transcription factor	postreplication repair	Biological process	-
BARX2	8538	BARX homeobox 2	DNA binding	Molecular function	10854790
TP53BP1	7158	tumor protein p53 binding protein 1	nucleus	Cellular component	-
BAD	572	BCL2-associated agonist of cell death	activation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	-
ING5	84289	inhibitor of growth family, member 5	negative regulation of growth	Biological process	12750254
AKAP8	10270	A kinase (PRKA) anchor protein 8	Golgi apparatus	Cellular component	-
KRAS	3845	Kirsten rat sarcoma viral oncogene homolog	insulin receptor signaling pathway	Biological process	-
FST	10468	follistatin	pattern specification process	Biological process	-
GPR68	8111	G protein-coupled receptor 68	negative regulation of monocyte differentiation	Biological process	-
UROD	7389	uroporphyrinogen decarboxylase	heme biosynthetic process	Biological process	-
ICAM3	3385	intercellular adhesion molecule 3	plasma membrane	Cellular component	-
RAP2A	5911	RAP2A, member of RAS oncogene family	midbody	Cellular component	-
TLE3	7090	transducin-like enhancer of split 3	organ morphogenesis	Biological process	8808280
ADRA2C	152	adrenoceptor alpha 2C	protein binding	Molecular function	16531006
MICALCL	84953	MICAL C-terminal like	spermatogenesis	Biological process	-
H1F0	3005	H1 histone family, member 0	actin cytoskeleton	Cellular component	-
PDPN	10630	podoplanin	apical plasma membrane	Cellular component	-
GNG7	2788	guanine nucleotide binding protein (G protein), gamma 7	synaptic transmission	Biological process	-
USH1C	10083	Usher syndrome 1C (autosomal recessive, severe)	inner ear morphogenesis	Biological process	-
GALNT5	11227	polypeptide N-acetylgalactosaminyltransferase 5	metal ion binding	Molecular function	-
CHUK	1147	conserved helix-loop-helix ubiquitous kinase	response to drug	Biological process	-
BRS3	680	bombesin-like receptor 3	bombesin receptor signaling pathway	Biological process	-
BRINP3	339479	bone morphogenetic protein/retinoic acid inducible neural-specific 3	endoplasmic reticulum	Cellular component	-
PSENEN	55851	presenilin enhancer gamma secretase subunit	positive regulation of apoptotic process	Biological process	-
SMAD7	4092	SMAD family member 7	transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity	Molecular function	9256479
C3	718	complement component 3	positive regulation of G-protein coupled receptor protein signaling pathway	Biological process	15833747
DDIT3	1649	DNA-damage-inducible transcript 3	leucine zipper domain binding	Molecular function	11478948
SIT1	27240	signaling threshold regulating transmembrane adaptor 1	extracellular exosome	Cellular component	20458337
CSNK2A2	1459	casein kinase 2, alpha prime polypeptide	Wnt signaling pathway	Biological process	-
GBA	2629	glucosidase, beta, acid	negative regulation of interleukin-6 production	Biological process	19279008
ZNF664	144348	zinc finger protein 664	metal ion binding	Molecular function	-
TMEM59	9528	transmembrane protein 59	lysosomal membrane	Cellular component	-
RPL9	6133	ribosomal protein L9	cytosolic large ribosomal subunit	Cellular component	12962325
GTF2A2	2958	general transcription factor IIA, 2, 12kDa	transcription factor TFIIA complex	Cellular component	7724559
HFE	3077	hemochromatosis	antigen processing and presentation of peptide antigen via MHC class I	Biological process	8696333
SLC33A1	9197	solute carrier family 33 (acetyl-CoA transporter), member 1	solute:proton symporter activity	Molecular function	-
TBX1	6899	T-box 1	angiogenesis	Biological process	-
PTPN1	5770	protein tyrosine phosphatase, non-receptor type 1	actin cytoskeleton reorganization	Biological process	21135139
ZNF519	162655	zinc finger protein 519	metal ion binding	Molecular function	-
COCH	1690	cochlin	extracellular exosome	Cellular component	23376485
ZNF439	90594	zinc finger protein 439	nucleus	Cellular component	-
DHRS13	147015	dehydrogenase/reductase (SDR family) member 13	membrane	Cellular component	19946888
RGPD3	653489	RANBP2-like and GRIP domain containing 3	intracellular	Cellular component	-
ZBTB18	10472	zinc finger and BTB domain containing 18	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
TRPC1	7220	transient receptor potential cation channel, subfamily C, member 1	plasma membrane	Cellular component	-
ITGB3	3690	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	focal adhesion	Cellular component	21423176
ANXA2	302	annexin A2	protein heterotetramerization	Biological process	23091277
RAD1	5810	RAD1 checkpoint DNA exonuclease	meiotic recombination checkpoint	Biological process	9716408
CACNB1	782	calcium channel, voltage-dependent, beta 1 subunit	voltage-gated calcium channel activity	Molecular function	1385409
IDO1	3620	indoleamine 2,3-dioxygenase 1	indoleamine 2,3-dioxygenase activity	Molecular function	25310899
TESC	54997	tescalcin	nucleoplasm	Cellular component	-
ARPC4	10093	actin related protein 2/3 complex, subunit 4, 20kDa	protein binding, bridging	Molecular function	11162547
DDC	1644	dopa decarboxylase (aromatic L-amino acid decarboxylase)	cellular nitrogen compound metabolic process	Biological process	-
RAD51B	5890	RAD51 paralog B	Rad51B-Rad51C-Rad51D-XRCC2 complex	Cellular component	11751635
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	Z disc	Cellular component	-
RPL7	6129	ribosomal protein L7	focal adhesion	Cellular component	21423176
CFTR	1080	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	intracellular pH elevation	Biological process	-
COL21A1	81578	collagen, type XXI, alpha 1	extracellular region	Cellular component	-
SMARCB1	6598	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	positive regulation by host of viral transcription	Biological process	16687403
IL12B	3593	interleukin 12B	protein homodimerization activity	Molecular function	-
NDUFV3	4731	NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa	mitochondrial respiratory chain complex I	Cellular component	9878551
F2RL1	2150	coagulation factor II (thrombin) receptor-like 1	integral component of plasma membrane	Cellular component	17848177
ITPR3	3710	inositol 1,4,5-trisphosphate receptor, type 3	inositol phosphate-mediated signaling	Biological process	-
PITX2	5308	paired-like homeodomain 2	positive regulation of transcription from RNA polymerase II promoter	Biological process	15466416
ATG7	10533	autophagy related 7	positive regulation of protein modification process	Biological process	12890687
Mar-05	54708	membrane-associated ring finger (C3HC4) 5	endoplasmic reticulum	Cellular component	14722266
PSMC2	5701	proteasome (prosome, macropain) 26S subunit, ATPase, 2	cytoplasm	Cellular component	16130169
PLA2G4E	123745	phospholipase A2, group IVE	lysosomal membrane	Cellular component	-
NOS3	4846	nitric oxide synthase 3 (endothelial cell)	lung development	Biological process	-
SLC3A2	6520	solute carrier family 3 (amino acid transporter heavy chain), member 2	nucleoplasm	Cellular component	-
CA5A	763	carbonic anhydrase VA, mitochondrial	mitochondrion	Cellular component	8356065
HIST1H4I	8294	histone cluster 1, H4i	protein complex	Cellular component	14718166
COPS2	9318	COP9 signalosome subunit 2	cullin deneddylation	Biological process	19141280
FXN	2395	frataxin	negative regulation of multicellular organism growth	Biological process	-
RUNX1	861	runt-related transcription factor 1	cytoplasm	Cellular component	-
DDX11	1663	DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11	ATP binding	Molecular function	-
TOMM7	54543	translocase of outer mitochondrial membrane 7 homolog (yeast)	mitochondrial outer membrane translocase complex	Cellular component	24270810
CKAP5	9793	cytoskeleton associated protein 5	membrane	Cellular component	19946888
CENPL	91687	centromere protein L	small GTPase mediated signal transduction	Biological process	-
FOXP3	50943	forkhead box P3	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
PRPF31	26121	pre-mRNA processing factor 31	protein binding	Molecular function	21385873
OBSL1	23363	obscurin-like 1	cytoskeleton organization	Biological process	17289344
MBP	4155	myelin basic protein	protein binding	Molecular function	17064692
SLC19A2	10560	solute carrier family 19 (thiamine transporter), member 2	integral component of membrane	Cellular component	10542220
PECR	55825	peroxisomal trans-2-enoyl-CoA reductase	trans-2-enoyl-CoA reductase (NADPH) activity	Molecular function	16546181
SULT1A2	6799	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2	cytosol	Cellular component	-
PON1	5444	paraoxonase 1	positive regulation of binding	Biological process	15721011
ATP6V1G1	9550	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1	phagosome maturation	Biological process	-
NFRKB	4798	nuclear factor related to kappaB binding protein	DNA recombination	Biological process	-
TRPM3	80036	transient receptor potential cation channel, subfamily M, member 3	transmembrane transport	Biological process	-
CENPU	79682	centromere protein U	nucleus	Cellular component	-
ATP6V0C	527	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c	transferrin transport	Biological process	-
DARS	1615	aspartyl-tRNA synthetase	membrane	Cellular component	19946888
FXYD1	5348	FXYD domain containing ion transport regulator 1	integral component of plasma membrane	Cellular component	-
NLRP5	126206	NLR family, pyrin domain containing 5	regulation of protein stability	Biological process	-
OR1L6	392390	olfactory receptor, family 1, subfamily L, member 6	integral component of membrane	Cellular component	-
FOSL1	8061	FOS-like antigen 1	positive regulation of sequence-specific DNA binding transcription factor activity	Biological process	-
SFRP1	6422	secreted frizzled-related protein 1	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification	Biological process	9192640
PTGER4	5734	prostaglandin E receptor 4 (subtype EP4)	negative regulation of inflammatory response	Biological process	16424369
MAP3K7	6885	mitogen-activated protein kinase kinase kinase 7	nucleotide-binding oligomerization domain containing signaling pathway	Biological process	-
ELOVL4	6785	ELOVL fatty acid elongase 4	very long-chain fatty acid biosynthetic process	Biological process	-
GSK3B	2932	glycogen synthase kinase 3 beta	negative regulation of protein binding	Biological process	16890161
NOS1	4842	nitric oxide synthase 1 (neuronal)	negative regulation of calcium ion transport	Biological process	-
IRAK1	3654	interleukin-1 receptor-associated kinase 1	protein oligomerization	Biological process	16831874
SREBF1	6720	sterol regulatory element binding transcription factor 1	circadian rhythm	Biological process	-
ZNF480	147657	zinc finger protein 480	regulation of transcription, DNA-templated	Biological process	-
MPHOSPH9	10198	M-phase phosphoprotein 9	membrane	Cellular component	19946888
NKX2-1	7080	NK2 homeobox 1	cerebral cortex cell migration	Biological process	-
ARHGEF2	9181	Rho/Rac guanine nucleotide exchange factor (GEF) 2	apoptotic signaling pathway	Biological process	-
OR7A17	26333	olfactory receptor, family 7, subfamily A, member 17	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
MESP2	145873	mesoderm posterior basic helix-loop-helix transcription factor 2	nucleus	Cellular component	-
ADCY5	111	adenylate cyclase 5	energy reserve metabolic process	Biological process	-
ERVK-18	100775105	endogenous retrovirus group K, member 18	structural molecule activity	Molecular function	-
DDIT4	54541	DNA-damage-inducible transcript 4	intracellular	Cellular component	-
ZKSCAN4	387032	zinc finger with KRAB and SCAN domains 4	regulation of transcription, DNA-templated	Biological process	-
LPAR5	57121	lysophosphatidic acid receptor 5	molecular_function	Molecular function	-
PON2	5445	paraoxonase 2	metal ion binding	Molecular function	-
ARRB2	409	arrestin, beta 2	G-protein coupled receptor internalization	Biological process	12582207
ZNF561	93134	zinc finger protein 561	metal ion binding	Molecular function	-
CD74	972	CD74 molecule, major histocompatibility complex, class II invariant chain	negative regulation of T cell differentiation	Biological process	-
HSP90AA1	3320	heat shock protein 90kDa alpha (cytosolic), class A member 1	mitochondrial transport	Biological process	12526792
ITM2B	9445	integral membrane protein 2B	intracellular membrane-bounded organelle	Cellular component	-
HSD17B12	51144	hydroxysteroid (17-beta) dehydrogenase 12	positive regulation of cell-substrate adhesion	Biological process	-
CALB1	793	calbindin 1, 28kDa	cytosolic calcium ion homeostasis	Biological process	-
PSMB9	5698	proteasome (prosome, macropain) subunit, beta type, 9	regulation of cellular amino acid metabolic process	Biological process	-
ATG9A	79065	autophagy related 9A	protein binding	Molecular function	19893488
IL17F	112744	interleukin 17F	cytokine binding	Molecular function	11574464
OSR2	116039	odd-skipped related transciption factor 2	embryonic forelimb morphogenesis	Biological process	-
TNNI3K	51086	TNNI3 interacting kinase	regulation of cardiac muscle contraction	Biological process	24925317
FECH	2235	ferrochelatase	generation of precursor metabolites and energy	Biological process	1729699
MEF2A	4205	myocyte enhancer factor 2A	sequence-specific DNA binding RNA polymerase II transcription factor activity	Molecular function	10748098
CPEB1	64506	cytoplasmic polyadenylation element binding protein 1	postsynaptic membrane	Cellular component	-
PNPLA7	375775	patatin-like phospholipase domain containing 7	integral component of membrane	Cellular component	-
GABRR1	2569	gamma-aminobutyric acid (GABA) A receptor, rho 1	transport	Biological process	1849271
PLCB1	23236	phospholipase C, beta 1 (phosphoinositide-specific)	protein binding	Molecular function	25416956
RORB	6096	RAR-related orphan receptor B	retina development in camera-type eye	Biological process	-
PRRT1	80863	proline-rich transmembrane protein 1	plasma membrane	Cellular component	-
PTPRR	5801	protein tyrosine phosphatase, receptor type, R	protein binding	Molecular function	10601328
PLXNB1	5364	plexin B1	semaphorin receptor activity	Molecular function	10520995
OR2M7	391196	olfactory receptor, family 2, subfamily M, member 7	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
MCPH1	79648	microcephalin 1	mitotic cell cycle	Biological process	-
DAB2	1601	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)	positive regulation of cell migration	Biological process	19581412
KDSR	2531	3-ketodihydrosphingosine reductase	oxidation-reduction process	Biological process	-
TRIM5	85363	tripartite motif containing 5	cytokine-mediated signaling pathway	Biological process	-
OLAH	55301	oleoyl-ACP hydrolase	oleoyl-[acyl-carrier-protein] hydrolase activity	Molecular function	-
ZHX2	22882	zinc fingers and homeoboxes 2	protein binding	Molecular function	12741956
EBP	10682	emopamil binding protein (sterol isomerase)	cholesterol biosynthetic process	Biological process	-
INS	3630	insulin	regulation of transmembrane transporter activity	Biological process	14615391
TGFBR2	7048	transforming growth factor, beta receptor II (70/80kDa)	aging	Biological process	-
VPS9D1	9605	VPS9 domain containing 1	transporter activity	Molecular function	10231027
EPB41L2	2037	erythrocyte membrane protein band 4.1-like 2	actin binding	Molecular function	-
CBFB	865	core-binding factor, beta subunit	osteoblast differentiation	Biological process	-
EPHA6	285220	EPH receptor A6	ATP binding	Molecular function	-
L3MBTL1	26013	l(3)mbt-like 1 (Drosophila)	nucleosomal histone binding	Molecular function	17540172
MRPL54	116541	mitochondrial ribosomal protein L54	poly(A) RNA binding	Molecular function	22681889
PCSK1	5122	proprotein convertase subtilisin/kexin type 1	peptide hormone processing	Biological process	-
LCP1	3936	lymphocyte cytosolic protein 1 (L-plastin)	podosome	Cellular component	24236012
PGM2	55276	phosphoglucomutase 2	magnesium ion binding	Molecular function	-
ACBD5	91452	acyl-CoA binding domain containing 5	macroautophagy	Biological process	24535825
CDKN2B	1030	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	cyclin-dependent protein serine/threonine kinase inhibitor activity	Molecular function	9230210
PPP1R14A	94274	protein phosphatase 1, regulatory (inhibitor) subunit 14A	small GTPase mediated signal transduction	Biological process	-
TMED3	23423	transmembrane emp24 protein transport domain containing 3	Golgi apparatus	Cellular component	12237308
FCHO1	23149	FCH domain only 1	coated pit	Cellular component	20448150
ADCYAP1	116	adenylate cyclase activating polypeptide 1 (pituitary)	neuropeptide hormone activity	Molecular function	23800469
CRYL1	51084	crystallin, lambda 1	extracellular exosome	Cellular component	19056867
PHF6	84295	PHD finger protein 6	regulation of transcription, DNA-templated	Biological process	-
APOE	348	apolipoprotein E	endocytic vesicle lumen	Cellular component	-
ABCD1	215	ATP-binding cassette, sub-family D (ALD), member 1	cytoplasm	Cellular component	17761426
LIPF	8513	lipase, gastric	mitochondrion	Cellular component	-
GPR61	83873	G protein-coupled receptor 61	G-protein coupled receptor signaling pathway	Biological process	-
TGM5	9333	transglutaminase 5	metal ion binding	Molecular function	-
SLC22A23	63027	solute carrier family 22, member 23	ion transport	Biological process	-
IRF5	3663	interferon regulatory factor 5	response to muramyl dipeptide	Biological process	22412986
MYLIP	29116	myosin regulatory light chain interacting protein	nervous system development	Biological process	10593918
BRCA2	675	breast cancer 2, early onset	BRCA2-MAGE-D1 complex	Cellular component	15930293
NPR2	4882	natriuretic peptide receptor 2	intracellular	Cellular component	-
GATA3	2625	GATA binding protein 3	anatomical structure formation involved in morphogenesis	Biological process	-
SPRY2	10253	sprouty homolog 2 (Drosophila)	negative regulation of fibroblast growth factor receptor signaling pathway	Biological process	-
ERCC8	1161	excision repair cross-complementation group 8	protein autoubiquitination	Biological process	12732143
RBM10	8241	RNA binding motif protein 10	nucleoplasm	Cellular component	-
ZNF365	22891	zinc finger protein 365	microtubule organizing center	Cellular component	-
LCP1	3936	lymphocyte cytosolic protein 1 (L-plastin)	calcium ion binding	Molecular function	2378651
TBL1X	6907	transducin (beta)-like 1X-linked	Notch signaling pathway	Biological process	-
RAF1	5894	Raf-1 proto-oncogene, serine/threonine kinase	protein phosphorylation	Biological process	8063729
TSPYL5	85453	TSPY-like 5	positive regulation of protein ubiquitination	Biological process	21170034
OR2J1	442185	olfactory receptor, family 2, subfamily J, member 1 (gene/pseudogene)	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
SERPINE2	5270	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2	glycosaminoglycan binding	Molecular function	19855083
MAP2K2	5605	mitogen-activated protein kinase kinase 2	positive regulation of protein serine/threonine kinase activity	Biological process	8388392
H2AFX	3014	H2A histone family, member X	DNA repair	Biological process	-
MDK	4192	midkine (neurite growth-promoting factor 2)	behavioral fear response	Biological process	-
ZNF384	171017	zinc finger protein 384	SH3 domain binding	Molecular function	-
IFIT1	3434	interferon-induced protein with tetratricopeptide repeats 1	cellular response to exogenous dsRNA	Biological process	19008854
NKX1-1	54729	NK1 homeobox 1	regulation of transcription, DNA-templated	Biological process	-
SIRT2	22933	sirtuin 2	lateral loop	Cellular component	-
WRN	7486	Werner syndrome, RecQ helicase-like	ATP binding	Molecular function	-
CYR61	3491	cysteine-rich, angiogenic inducer, 61	regulation of ERK1 and ERK2 cascade	Biological process	20675382
PLN	5350	phospholamban	negative regulation of calcium-transporting ATPase activity	Biological process	19708671
SNIP1	79753	Smad nuclear interacting protein 1	protein binding	Molecular function	17157259
RIPK2	8767	receptor-interacting serine-threonine kinase 2	cellular response to peptidoglycan	Biological process	-
HOXB8	3218	homeobox B8	transcription, DNA-templated	Biological process	-
RRM2	6241	ribonucleotide reductase M2	protein binding	Molecular function	22632967
VAMP4	8674	vesicle-associated membrane protein 4	trans-Golgi network	Cellular component	-
SNCG	6623	synuclein, gamma (breast cancer-specific protein 1)	perinuclear region of cytoplasm	Cellular component	-
TIMM13	26517	translocase of inner mitochondrial membrane 13 homolog (yeast)	protein targeting to mitochondrion	Biological process	-
KLRC2	3822	killer cell lectin-like receptor subfamily C, member 2	protein binding	Molecular function	18448674
POLR2L	5441	polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa	transcription initiation from RNA polymerase I promoter	Biological process	-
TMLHE	55217	trimethyllysine hydroxylase, epsilon	small molecule metabolic process	Biological process	-
VIM	7431	vimentin	focal adhesion	Cellular component	21423176
NUDT5	11164	nudix (nucleoside diphosphate linked moiety X)-type motif 5	ADP-sugar diphosphatase activity	Molecular function	10567213
OR5B2	390190	olfactory receptor, family 5, subfamily B, member 2	integral component of plasma membrane	Cellular component	-
NEK9	91754	NIMA-related kinase 9	cytosol	Cellular component	-
TCF21	6943	transcription factor 21	branching involved in ureteric bud morphogenesis	Biological process	-
USP16	10600	ubiquitin specific peptidase 16	ubiquitin binding	Molecular function	17512543
TRPV2	51393	transient receptor potential cation channel, subfamily V, member 2	positive regulation of calcium ion import	Biological process	-
PCSK9	255738	proprotein convertase subtilisin/kexin type 9	neurogenesis	Biological process	12552133
ASCL1	429	achaete-scute family bHLH transcription factor 1	commitment of neuronal cell to specific neuron type in forebrain	Biological process	-
RAB17	64284	RAB17, member RAS oncogene family	neuronal cell body	Cellular component	-
CIAO1	9391	cytosolic iron-sulfur assembly component 1	positive regulation of cell proliferation	Biological process	9556563
PTEN	5728	phosphatase and tensin homolog	negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle	Biological process	21241890
CXCL16	58191	chemokine (C-X-C motif) ligand 16	scavenger receptor activity	Molecular function	11060282
SREBF2	6721	sterol regulatory element binding transcription factor 2	negative regulation of cholesterol efflux	Biological process	15358760
LZIC	84328	leucine zipper and CTNNBIP1 domain containing	beta-catenin binding	Molecular function	-
RASGEF1A	221002	RasGEF domain family, member 1A	positive regulation of GTPase activity	Biological process	-
RORC	6097	RAR-related orphan receptor C	oxysterol binding	Molecular function	19965867
SIRT5	23408	sirtuin 5	protein desuccinylation	Biological process	24140062
HOGA1	112817	4-hydroxy-2-oxoglutarate aldolase 1	glyoxylate catabolic process	Biological process	20797690
FSCN2	25794	fascin actin-bundling protein 2, retinal	actin filament bundle assembly	Biological process	10783262
TET1	80312	tet methylcytosine dioxygenase 1	oxidative DNA demethylation	Biological process	-
HERPUD1	9709	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	regulation of protein ubiquitination	Biological process	-
RAB9A	9367	RAB9A, member RAS oncogene family	endoplasmic reticulum membrane	Cellular component	-
AKAP6	9472	A kinase (PRKA) anchor protein 6	cytoplasm	Cellular component	-
APBB1	322	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	transcription, DNA-templated	Biological process	-
TAF9	6880	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa	viral process	Biological process	-
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	small GTPase mediated signal transduction	Biological process	-
RCC1	1104	regulator of chromosome condensation 1	nuclear chromatin	Cellular component	15014043
CCT6A	908	chaperonin containing TCP1, subunit 6A (zeta 1)	cellular protein metabolic process	Biological process	-
FES	2242	FES proto-oncogene, tyrosine kinase	chemotaxis	Biological process	-
PARP14	54625	poly (ADP-ribose) polymerase family, member 14	regulation of transcription, DNA-templated	Biological process	-
MEN1	4221	multiple endocrine neoplasia I	negative regulation of transcription, DNA-templated	Biological process	12226747
HP	3240	haptoglobin	protein binding	Molecular function	19758344
SLC19A2	10560	solute carrier family 19 (thiamine transporter), member 2	folic acid transporter activity	Molecular function	10542220
MOB4	25843	MOB family member 4, phocein	perinuclear region of cytoplasm	Cellular component	-
EIF6	3692	eukaryotic translation initiation factor 6	ribosomal subunit export from nucleus	Biological process	-
DRD3	1814	dopamine receptor D3	cell projection	Cellular component	-
CAMK2G	818	calcium/calmodulin-dependent protein kinase II gamma	calmodulin binding	Molecular function	9060999
MGST1	4257	microsomal glutathione S-transferase 1	response to organonitrogen compound	Biological process	-
AKIRIN2	55122	akirin 2	transcriptional repressor complex	Cellular component	-
MAP1LC3A	84557	microtubule-associated protein 1 light chain 3 alpha	membrane fusion	Biological process	-
TMCO6	55374	transmembrane and coiled-coil domains 6	nucleus	Cellular component	-
CYP4Z1	199974	cytochrome P450, family 4, subfamily Z, polypeptide 1	oxidation-reduction process	Biological process	-
FGFR2	2263	fibroblast growth factor receptor 2	lateral sprouting from an epithelium	Biological process	-
OR1J1	347168	olfactory receptor, family 1, subfamily J, member 1	olfactory receptor activity	Molecular function	-
HCFC2	29915	host cell factor C2	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
SDC2	6383	syndecan 2	chondroitin sulfate metabolic process	Biological process	-
SYT1	6857	synaptotagmin I	vesicle docking	Biological process	-
PHF2	5253	PHD finger protein 2	histone demethylase activity	Molecular function	21167174
CRTC1	23373	CREB regulated transcription coactivator 1	protein homotetramerization	Biological process	-
SETMAR	6419	SET domain and mariner transposase fusion gene	negative regulation of cell cycle arrest	Biological process	19390626
LIG4	3981	ligase IV, DNA, ATP-dependent	focal adhesion	Cellular component	-
CHRNA4	1137	cholinergic receptor, nicotinic, alpha 4 (neuronal)	postsynaptic membrane	Cellular component	-
TP63	8626	tumor protein p63	transcription regulatory region DNA binding	Molecular function	-
CD93	22918	CD93 molecule	viral process	Biological process	-
ZNF219	51222	zinc finger protein 219	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	14621294
LPXN	9404	leupaxin	cell projection	Cellular component	-
PNPLA3	80339	patatin-like phospholipase domain containing 3	integral component of membrane	Cellular component	-
GHRH	2691	growth hormone releasing hormone	terminal bouton	Cellular component	-
DIRAS1	148252	DIRAS family, GTP-binding RAS-like 1	GTP binding	Molecular function	12194967
MAN1A1	4121	mannosidase, alpha, class 1A, member 1	Golgi membrane	Cellular component	-
EMC8	10328	ER membrane protein complex subunit 8	ER membrane protein complex	Cellular component	22119785
FBXL7	23194	F-box and leucine-rich repeat protein 7	cell proliferation	Biological process	-
KCNK2	3776	potassium channel, two pore domain subfamily K, member 2	potassium ion leak channel activity	Molecular function	-
ACSL3	2181	acyl-CoA synthetase long-chain family member 3	Golgi apparatus	Cellular component	20605918
DEFB103B	55894	defensin, beta 103B	defense response to bacterium	Biological process	-
GRIN3A	116443	glutamate receptor, ionotropic, N-methyl-D-aspartate 3A	neuron projection	Cellular component	17658481
PRKACA	5566	protein kinase, cAMP-dependent, catalytic, alpha	regulation of insulin secretion	Biological process	-
NRG1	3084	neuregulin 1	fibroblast growth factor receptor signaling pathway	Biological process	-
CHRNB2	1141	cholinergic receptor, nicotinic, beta 2 (neuronal)	learning	Biological process	15964197
RXRA	6256	retinoid X receptor, alpha	RNA polymerase II regulatory region sequence-specific DNA binding	Molecular function	7831303
CDK2	1017	cyclin-dependent kinase 2	positive regulation of cell proliferation	Biological process	10767298
SRGN	5552	serglycin	platelet alpha granule lumen	Cellular component	-
TRIM33	51592	tripartite motif containing 33	co-SMAD binding	Molecular function	19135894
FUT3	2525	fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)	oligosaccharide biosynthetic process	Biological process	1977660
OSBPL5	114879	oxysterol binding protein-like 5	cytosol	Cellular component	10588946
FFAR3	2865	free fatty acid receptor 3	G-protein coupled receptor signaling pathway	Biological process	12496283
TBX5	6910	T-box 5	cell migration involved in coronary vasculogenesis	Biological process	20299672
CCDC88C	440193	coiled-coil domain containing 88C	stress-activated protein kinase signaling cascade	Biological process	25062847
STXBP3	6814	syntaxin binding protein 3	cytosol	Cellular component	-
WNT3A	89780	wingless-type MMTV integration site family, member 3A	palate development	Biological process	18413325
PDPK1	5170	3-phosphoinositide dependent protein kinase 1	ATP binding	Molecular function	-
LIN9	286826	lin-9 DREAM MuvB core complex component	nucleoplasm	Cellular component	-
NFKBIE	4794	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	Golgi apparatus	Cellular component	-
PAX3	5077	paired box 3	heart development	Biological process	-
TBX5	6910	T-box 5	protein binding	Molecular function	11431700
SRC	6714	SRC proto-oncogene, non-receptor tyrosine kinase	axon guidance	Biological process	-
PRMT5	10419	protein arginine methyltransferase 5	histone-arginine N-methyltransferase activity	Molecular function	-
NR4A1	3164	nuclear receptor subfamily 4, group A, member 1	protein binding	Molecular function	17139261
PDGFRB	5159	platelet-derived growth factor receptor, beta polypeptide	positive regulation of phospholipase C activity	Biological process	1653029
TRMT10A	93587	tRNA methyltransferase 10 homolog A (S. cerevisiae)	tRNA binding	Molecular function	25053765
PPAT	5471	phosphoribosyl pyrophosphate amidotransferase	nucleobase-containing small molecule metabolic process	Biological process	-
RPL35A	6165	ribosomal protein L35a	cytosolic large ribosomal subunit	Cellular component	12962325
VEGFA	7422	vascular endothelial growth factor A	cytoplasm	Cellular component	17082651
INSL4	3641	insulin-like 4 (placenta)	cell-cell signaling	Biological process	8702754
CTH	1491	cystathionine gamma-lyase	homocysteine desulfhydrase activity	Molecular function	-
REC8	9985	REC8 meiotic recombination protein	oocyte maturation	Biological process	-
B2M	567	beta-2-microglobulin	protein binding	Molecular function	10638746
GMPR2	51292	guanosine monophosphate reductase 2	GMP reductase activity	Molecular function	22037469
TPBG	7162	trophoblast glycoprotein	cell adhesion	Biological process	10366710
TERF2	7014	telomeric repeat binding factor 2	nucleoplasm	Cellular component	-
ZNF169	169841	zinc finger protein 169	regulation of transcription, DNA-templated	Biological process	-
TRIP6	7205	thyroid hormone receptor interactor 6	positive regulation of cell migration	Biological process	14688263
MAP2K4	6416	mitogen-activated protein kinase kinase 4	toll-like receptor 2 signaling pathway	Biological process	-
ADGRE1	2015	adhesion G protein-coupled receptor E1	integral component of plasma membrane	Cellular component	7601460
PTPDC1	138639	protein tyrosine phosphatase domain containing 1	peptidyl-tyrosine dephosphorylation	Biological process	-
CDK12	51755	cyclin-dependent kinase 12	cyclin-dependent protein serine/threonine kinase activity	Molecular function	-
RABGGTA	5875	Rab geranylgeranyltransferase, alpha subunit	cellular protein modification process	Biological process	2018975
TP53	7157	tumor protein p53	multicellular organismal development	Biological process	10065150
LAMB4	22798	laminin, beta 4	cell adhesion	Biological process	-
KIR2DL3	3804	killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3	integral component of membrane	Cellular component	7749980
NRP1	8829	neuropilin 1	axonogenesis involved in innervation	Biological process	-
FHL5	9457	four and a half LIM domains 5	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
SCAI	286205	suppressor of cancer cell invasion	protein binding	Molecular function	19350017
SMOC1	64093	SPARC related modular calcium binding 1	basement membrane	Cellular component	-
ITGA1	3672	integrin, alpha 1	neutrophil chemotaxis	Biological process	-
CCNL1	57018	cyclin L1	RNA processing	Biological process	-
ALDH1A2	8854	aldehyde dehydrogenase 1 family, member A2	cardiac muscle tissue development	Biological process	-
ISL1	3670	ISL LIM homeobox 1	atrial septum morphogenesis	Biological process	-
TNFSF10	8743	tumor necrosis factor (ligand) superfamily, member 10	integral component of plasma membrane	Cellular component	8663110
EDRF1	26098	erythroid differentiation regulatory factor 1	nucleus	Cellular component	-
SLC30A5	64924	solute carrier family 30 (zinc transporter), member 5	zinc II ion transport	Biological process	10330022
COMT	1312	catechol-O-methyltransferase	magnesium ion binding	Molecular function	-
RASGRF1	5923	Ras protein-specific guanine nucleotide-releasing factor 1	guanyl-nucleotide exchange factor activity	Molecular function	1379731
PRPF19	27339	pre-mRNA processing factor 19	catalytic step 2 spliceosome	Cellular component	11991638
CDC14B	8555	cell division cycle 14B	peptidyl-tyrosine dephosphorylation	Biological process	-
HMGA1	3159	high mobility group AT-hook 1	DNA-(apurinic or apyrimidinic site) lyase activity	Molecular function	19465398
APOBR	55911	apolipoprotein B receptor	low-density lipoprotein particle	Cellular component	-
GAMT	2593	guanidinoacetate N-methyltransferase	cytosol	Cellular component	-
GHSR	2693	growth hormone secretagogue receptor	negative regulation of tumor necrosis factor biosynthetic process	Biological process	15232612
KLRF2	100431172	killer cell lectin-like receptor subfamily F, member 2	natural killer cell degranulation	Biological process	20194751
NDUFAF1	51103	NADH dehydrogenase (ubiquinone) complex I, assembly factor 1	protein complex assembly	Biological process	11935339
CBX8	57332	chromobox homolog 8	nuclear chromatin	Cellular component	19636380
KCNJ12	3768	potassium channel, inwardly rectifying subfamily J, member 12	regulation of heart contraction	Biological process	7859381
WDR3	10885	WD repeat domain 3	snoRNA binding	Molecular function	-
NEUROD2	4761	neuronal differentiation 2	behavioral fear response	Biological process	-
FOXK2	3607	forkhead box K2	nucleoplasm	Cellular component	-
PLA2G16	11145	phospholipase A2, group XVI	phospholipase A2 activity	Molecular function	20100577
ERMAP	114625	erythroblast membrane-associated protein (Scianna blood group)	plasma membrane	Cellular component	11549310
KRTAP12-4	386684	keratin associated protein 12-4	keratin filament	Cellular component	-
HSP90AA1	3320	heat shock protein 90kDa alpha (cytosolic), class A member 1	cellular response to heat	Biological process	-
ACVR2B	93	activin A receptor, type IIB	heart development	Biological process	-
MAP1LC3B	81631	microtubule-associated protein 1 light chain 3 beta	endomembrane system	Cellular component	-
B3GNT7	93010	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7	post-translational protein modification	Biological process	-
FLT1	2321	fms-related tyrosine kinase 1	vascular endothelial growth factor-activated receptor activity	Molecular function	11312102
GRB10	2887	growth factor receptor-bound protein 10	negative regulation of Wnt signaling pathway	Biological process	17376403
CSDC2	27254	cold shock domain containing C2, RNA binding	DNA binding	Molecular function	-
MCM7	4176	minichromosome maintenance complex component 7	protein binding	Molecular function	10518787
LIG3	3980	ligase III, DNA, ATP-dependent	cytoplasm	Cellular component	-
CSGALNACT1	55790	chondroitin sulfate N-acetylgalactosaminyltransferase 1	chondroitin sulfate biosynthetic process	Biological process	-
KCNH4	23415	potassium channel, voltage gated eag related subfamily H, member 4	phosphorelay sensor kinase activity	Molecular function	-
LONP1	9361	lon peptidase 1, mitochondrial	ADP binding	Molecular function	14739292
APOPT1	84334	apoptogenic 1, mitochondrial	positive regulation of smooth muscle cell apoptotic process	Biological process	-
PAPOLG	64895	poly(A) polymerase gamma	RNA binding	Molecular function	-
TACSTD2	4070	tumor-associated calcium signal transducer 2	negative regulation of stress fiber assembly	Biological process	-
AKT1	207	v-akt murine thymoma viral oncogene homolog 1	glycogen biosynthetic process	Biological process	-
SBF2	81846	SET binding factor 2	protein binding	Molecular function	15998640
CHRNA6	8973	cholinergic receptor, nicotinic, alpha 6 (neuronal)	acetylcholine-activated cation-selective channel activity	Molecular function	-
PDPK1	5170	3-phosphoinositide dependent protein kinase 1	focal adhesion	Cellular component	-
MIXL1	83881	Mix paired-like homeobox	protein homodimerization activity	Molecular function	22164283
FASLG	356	Fas ligand (TNF superfamily, member 6)	protein binding	Molecular function	12198154
ZNF655	79027	zinc finger protein 655	DNA binding	Molecular function	-
S1PR1	1901	sphingosine-1-phosphate receptor 1	plasma membrane	Cellular component	-
PDHB	5162	pyruvate dehydrogenase (lipoamide) beta	pyruvate dehydrogenase (acetyl-transferring) activity	Molecular function	-
PLD1	5337	phospholipase D1, phosphatidylcholine-specific	phospholipase D activity	Molecular function	-
MAST1	22983	microtubule associated serine/threonine kinase 1	protein binding	Molecular function	20029029
BAK1	578	BCL2-antagonist/killer 1	establishment or maintenance of transmembrane electrochemical gradient	Biological process	9843949
GMPR2	51292	guanosine monophosphate reductase 2	metal ion binding	Molecular function	-
NT5M	56953	5',3'-nucleotidase, mitochondrial	nucleobase-containing small molecule metabolic process	Biological process	-
PLA2G15	23659	phospholipase A2, group XV	ceramide metabolic process	Biological process	-
RPN2	6185	ribophorin II	dolichyl-diphosphooligosaccharide-protein glycotransferase activity	Molecular function	15835887
CTSS	1520	cathepsin S	adaptive immune response	Biological process	15196205
NOS1AP	9722	nitric oxide synthase 1 (neuronal) adaptor protein	regulation of nitric oxide biosynthetic process	Biological process	20431962
LDB1	8861	LIM domain binding 1	enhancer sequence-specific DNA binding	Molecular function	-
TOP2B	7155	topoisomerase (DNA) II beta 180kDa	cytoplasm	Cellular component	-
SP140	11262	SP140 nuclear body protein	defense response	Biological process	8910577
TAF3	83860	TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa	nucleus	Cellular component	15870280
EDN1	1906	endothelin 1	artery smooth muscle contraction	Biological process	1725334
PPP2R2A	5520	protein phosphatase 2, regulatory subunit B, alpha	protein dephosphorylation	Biological process	1849734
MKLN1	4289	muskelin 1, intracellular mediator containing kelch motifs	cytosol	Cellular component	-
CAPN8	388743	calpain 8	proteolysis	Biological process	-
RNLS	55328	renalase, FAD-dependent amine oxidase	response to ischemia	Biological process	-
MAN2A1	4124	mannosidase, alpha, class 2A, member 1	retina morphogenesis in camera-type eye	Biological process	-
ITGA7	3679	integrin, alpha 7	protein heterodimerization activity	Molecular function	-
USP4	7375	ubiquitin specific peptidase 4 (proto-oncogene)	regulation of proteasomal protein catabolic process	Biological process	-
TACR2	6865	tachykinin receptor 2	positive regulation of vascular permeability	Biological process	-
CDK5R1	8851	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	neuronal cell body	Cellular component	-
PADI3	51702	peptidyl arginine deiminase, type III	calcium ion binding	Molecular function	-
BUB1B	701	BUB1 mitotic checkpoint serine/threonine kinase B	cytosol	Cellular component	-
ROBO1	6091	roundabout, axon guidance receptor, homolog 1 (Drosophila)	axon guidance	Biological process	-
LIG3	3980	ligase III, DNA, ATP-dependent	double-strand break repair via alternative nonhomologous end joining	Biological process	24837021
BYSL	705	bystin-like	cell proliferation	Biological process	-
GAL3ST3	89792	galactose-3-O-sulfotransferase 3	Golgi cisterna membrane	Cellular component	-
MNX1	3110	motor neuron and pancreas homeobox 1	endocrine pancreas development	Biological process	-
HRAS	3265	Harvey rat sarcoma viral oncogene homolog	signal transduction	Biological process	8607982
RABAC1	10567	Rab acceptor 1 (prenylated)	protein binding	Molecular function	16189514
GCDH	2639	glutaryl-CoA dehydrogenase	mitochondrial matrix	Cellular component	-
GLUL	2752	glutamate-ammonia ligase	glial cell projection	Cellular component	-
LAMA4	3910	laminin, alpha 4	extracellular matrix organization	Biological process	-
KIN	22944	Kin17 DNA and RNA binding protein	DNA recombination	Biological process	-
BRF1	2972	BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit	transcription from RNA polymerase III promoter	Biological process	-
OR9A1P	26495	olfactory receptor, family 9, subfamily A, member 1 pseudogene	plasma membrane	Cellular component	-
BIK	638	BCL2-interacting killer (apoptosis-inducing)	mitochondrial membrane	Cellular component	-
PAK1IP1	55003	PAK1 interacting protein 1	negative regulation of signal transduction	Biological process	-
CAMK1	8536	calcium/calmodulin-dependent protein kinase I	positive regulation of dendritic spine development	Biological process	18184567
FIZ1	84922	FLT3-interacting zinc finger 1	nucleic acid binding	Molecular function	-
TRPA1	8989	transient receptor potential cation channel, subfamily A, member 1	plasma membrane	Cellular component	-
ADARB1	104	adenosine deaminase, RNA-specific, B1	adenosine to inosine editing	Biological process	-
FOXD4L1	200350	forkhead box D4-like 1	nucleus	Cellular component	-
TRPC7	57113	transient receptor potential cation channel, subfamily C, member 7	ion transmembrane transport	Biological process	-
UNC13C	440279	unc-13 homolog C (C. elegans)	cytoplasm	Cellular component	-
C21orf2	755	chromosome 21 open reading frame 2	cytoplasm	Cellular component	21834987
ICE1	23379	interactor of little elongation complex ELL subunit 1	positive regulation of protein complex assembly	Biological process	23932780
KLHL12	59349	kelch-like family member 12	Cul3-RING ubiquitin ligase complex	Cellular component	22358839
POLR2A	5430	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	poly(A) RNA binding	Molecular function	22658674
PCDH11X	27328	protocadherin 11 X-linked	negative regulation of phosphatase activity	Biological process	19389623
TMEM91	641649	transmembrane protein 91	response to biotic stimulus	Biological process	-
KLHL42	57542	kelch-like family member 42	cell division	Biological process	-
SHMT2	6472	serine hydroxymethyltransferase 2 (mitochondrial)	positive regulation of cell proliferation	Biological process	-
GBGT1	26301	globoside alpha-1,3-N-acetylgalactosaminyltransferase 1	metal ion binding	Molecular function	-
PIK3CG	5294	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	cytosol	Cellular component	-
TF	7018	transferrin	transmembrane transport	Biological process	-
UBE2L6	9246	ubiquitin-conjugating enzyme E2L 6	cytokine-mediated signaling pathway	Biological process	-
DOCK2	1794	dedicator of cytokinesis 2	cytosol	Cellular component	-
PPARG	5468	peroxisome proliferator-activated receptor gamma	innate immune response	Biological process	17145956
SEC24B	10427	SEC24 family member B	lung lobe morphogenesis	Biological process	-
FOLR1	2348	folate receptor 1 (adult)	membrane	Cellular component	2768245
SPO11	23626	SPO11 meiotic protein covalently bound to DSB	male meiosis I	Biological process	-
IST1	9798	increased sodium tolerance 1 homolog (yeast)	positive regulation of proteolysis	Biological process	20849418
VDR	7421	vitamin D (1,25- dihydroxyvitamin D3) receptor	vitamin D receptor signaling pathway	Biological process	16549446
GRK4	2868	G protein-coupled receptor kinase 4	ATP binding	Molecular function	-
KLK15	55554	kallikrein-related peptidase 15	extracellular region	Cellular component	-
ARPC3	10094	actin related protein 2/3 complex, subunit 3, 21kDa	focal adhesion	Cellular component	21423176
KIT	3815	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	visual learning	Biological process	-
IGHMBP2	3508	immunoglobulin mu binding protein 2	tRNA binding	Molecular function	19299493
ADD3	120	adducin 3 (gamma)	cytosol	Cellular component	-
CMKLR1	1240	chemerin chemokine-like receptor 1	chemokine-mediated signaling pathway	Biological process	9425281
DNAJC21	134218	DnaJ (Hsp40) homolog, subfamily C, member 21	protein binding	Molecular function	17500595
NUP93	9688	nucleoporin 93kDa	nuclear periphery	Cellular component	15229283
EYA1	2138	EYA transcriptional coactivator and phosphatase 1	cytoplasm	Cellular component	19497856
Sep-05	5413	septin 5	GTP binding	Molecular function	-
RCHY1	25898	ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase	zinc ion binding	Molecular function	19043414
ALOX12	239	arachidonate 12-lipoxygenase	lipoxin B4 biosynthetic process	Biological process	8250832
UVRAG	7405	UV radiation resistance associated	receptor catabolic process	Biological process	20643123
CAV1	857	caveolin 1, caveolae protein, 22kDa	regulation of nitric-oxide synthase activity	Biological process	-
ZNF567	163081	zinc finger protein 567	transcription, DNA-templated	Biological process	-
WFDC3	140686	WAP four-disulfide core domain 3	extracellular region	Cellular component	-
SH3GLB1	51100	SH3-domain GRB2-like endophilin B1	cellular response to amino acid starvation	Biological process	21068542
SLC17A7	57030	solute carrier family 17 (vesicular glutamate transporter), member 7	clathrin-sculpted glutamate transport vesicle membrane	Cellular component	-
PKD1L3	342372	polycystic kidney disease 1-like 3	kidney development	Biological process	-
RRAGC	64121	Ras-related GTP binding C	apoptotic process	Biological process	11073942
ATG9A	79065	autophagy related 9A	late nucleophagy	Biological process	-
ZSCAN4	201516	zinc finger and SCAN domain containing 4	metal ion binding	Molecular function	-
PCBP2	5094	poly(rC) binding protein 2	nucleus	Cellular component	22720776
ADH1B	125	alcohol dehydrogenase 1B (class I), beta polypeptide	ethanol oxidation	Biological process	-
CER1	9350	cerberus 1, DAN family BMP antagonist	sequestering of BMP in extracellular matrix	Biological process	-
RHOXF1	158800	Rhox homeobox family, member 1	nucleus	Cellular component	11980563
PON3	5446	paraoxonase 3	3,4-dihydrocoumarin hydrolase activity	Molecular function	-
BBS2	583	Bardet-Biedl syndrome 2	melanosome transport	Biological process	-
KMT2B	9757	lysine (K)-specific methyltransferase 2B	histone H3-K4 methylation	Biological process	17166833
PRKY	5616	protein kinase, Y-linked, pseudogene	protein serine/threonine kinase activity	Molecular function	-
DLX4	1748	distal-less homeobox 4	protein binding	Molecular function	17474147
PLA2G4B	100137049	phospholipase A2, group IVB (cytosolic)	endoplasmic reticulum unfolded protein response	Biological process	-
MRPL20	55052	mitochondrial ribosomal protein L20	rRNA binding	Molecular function	-
AEN	64782	apoptosis enhancing nuclease	nuclear membrane	Cellular component	-
FABP4	2167	fatty acid binding protein 4, adipocyte	cellular response to lithium ion	Biological process	-
CRNN	49860	cornulin	membrane	Cellular component	2980212
CDK16	5127	cyclin-dependent kinase 16	cell junction	Cellular component	-
ATL2	64225	atlastin GTPase 2	metabolic process	Biological process	18270207
B4GALNT3	283358	beta-1,4-N-acetyl-galactosaminyl transferase 3	metabolic process	Biological process	-
GALNT7	51809	polypeptide N-acetylgalactosaminyltransferase 7	extracellular exosome	Cellular component	23533145
RNF208	727800	ring finger protein 208	protein autoubiquitination	Biological process	24105792
ZNF607	84775	zinc finger protein 607	DNA binding	Molecular function	-
PJA2	9867	praja ring finger 2, E3 ubiquitin protein ligase	protein ubiquitination	Biological process	-
CEP68	23177	centrosomal protein 68kDa	protein binding	Molecular function	25416956
DBI	1622	diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)	behavioral fear response	Biological process	-
KMO	8564	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	NAD metabolic process	Biological process	-
GRIN2B	2904	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	neuronal postsynaptic density	Cellular component	-
CFL1	1072	cofilin 1 (non-muscle)	axon guidance	Biological process	-
PNPT1	87178	polyribonucleotide nucleotidyltransferase 1	positive regulation of mRNA catabolic process	Biological process	16410805
APOA1	335	apolipoprotein A-I	plasma membrane	Cellular component	-
CAT	847	catalase	protein homotetramerization	Biological process	21976670
PSMD11	5717	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	cytosol	Cellular component	-
ABLIM3	22885	actin binding LIM protein family, member 3	actin binding	Molecular function	-
PLIN3	10226	perilipin 3	protein binding	Molecular function	19490898
HIST1H3I	8354	histone cluster 1, H3i	protein heterotetramerization	Biological process	20498094
YIPF3	25844	Yip1 domain family, member 3	cell differentiation	Biological process	-
POLA2	23649	polymerase (DNA directed), alpha 2, accessory subunit	DNA replication	Biological process	8223465
SNX1	6642	sorting nexin 1	lamellipodium	Cellular component	-
S100A7	6278	S100 calcium binding protein A7	positive regulation of T cell chemotaxis	Biological process	18606705
OR2K2	26248	olfactory receptor, family 2, subfamily K, member 2	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
SIRT1	23411	sirtuin 1	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	Biological process	17317627
TNFRSF8	943	tumor necrosis factor receptor superfamily, member 8	signal transduction	Biological process	-
MCAT	27349	malonyl CoA:ACP acyltransferase (mitochondrial)	[acyl-carrier-protein] S-malonyltransferase activity	Molecular function	12882974
MTHFR	4524	methylenetetrahydrofolate reductase (NAD(P)H)	response to vitamin B2	Biological process	-
NEFL	4747	neurofilament, light polypeptide	cytosol	Cellular component	-
PLD2	5338	phospholipase D2	inositol lipid-mediated signaling	Biological process	-
CEP128	145508	centrosomal protein 128kDa	microtubule organizing center	Cellular component	-
FBXO10	26267	F-box protein 10	regulation of apoptotic process	Biological process	23431138
MYOD1	4654	myogenic differentiation 1	myoblast fate determination	Biological process	-
KIF15	56992	kinesin family member 15	ATPase activity	Molecular function	-
ARG1	383	arginase 1	extracellular exosome	Cellular component	23376485
ADGRL2	23266	adhesion G protein-coupled receptor L2	G-protein coupled receptor activity	Molecular function	-
ITGA2	3673	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	cell adhesion mediated by integrin	Biological process	11518510
SPTLC3	55304	serine palmitoyltransferase, long chain base subunit 3	sphingolipid biosynthetic process	Biological process	19416851
FGFR1OP	11116	FGFR1 oncogene partner	G2/M transition of mitotic cell cycle	Biological process	-
ACLY	47	ATP citrate lyase	long-chain fatty-acyl-CoA biosynthetic process	Biological process	-
EPB41L5	57669	erythrocyte membrane protein band 4.1 like 5	posttranscriptional regulation of gene expression	Biological process	-
IL11	3589	interleukin 11	fat cell differentiation	Biological process	1828438
ATP6AP2	10159	ATPase, H+ transporting, lysosomal accessory protein 2	extracellular exosome	Cellular component	19056867
SHH	6469	sonic hedgehog	Bergmann glial cell differentiation	Biological process	-
AGXT	189	alanine-glyoxylate aminotransferase	L-cysteine catabolic process	Biological process	18492492
FOXH1	8928	forkhead box H1	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
AOX1	316	aldehyde oxidase 1	vitamin B6 metabolic process	Biological process	-
CSNK1A1L	122011	casein kinase 1, alpha 1-like	regulation of cell shape	Biological process	-
BATF	10538	basic leucine zipper transcription factor, ATF-like	T-helper 17 cell lineage commitment	Biological process	-
CCL8	6355	chemokine (C-C motif) ligand 8	extracellular space	Cellular component	-
DEFA3	1668	defensin, alpha 3, neutrophil-specific	defense response to Gram-positive bacterium	Biological process	12860195
ARHGEF7	8874	Rho guanine nucleotide exchange factor (GEF) 7	neuronal cell body	Cellular component	21048939
KCNQ2	3785	potassium channel, voltage gated KQT-like subfamily Q, member 2	synaptic transmission	Biological process	-
POU5F1	5460	POU class 5 homeobox 1	miRNA binding	Molecular function	18710938
HRAS	3265	Harvey rat sarcoma viral oncogene homolog	chemotaxis	Biological process	10848592
PTGS1	5742	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	response to oxidative stress	Biological process	-
HK3	3101	hexokinase 3 (white cell)	mitochondrion	Cellular component	-
SEH1L	81929	SEH1-like (S. cerevisiae)	cellular protein metabolic process	Biological process	-
SHC1	6464	SHC (Src homology 2 domain containing) transforming protein 1	mitochondrial matrix	Cellular component	-
SNAPIN	23557	SNAP-associated protein	endosome to lysosome transport	Biological process	22797916
ZNF324B	388569	zinc finger protein 324B	metal ion binding	Molecular function	-
GREM1	26585	gremlin 1, DAN family BMP antagonist	positive regulation of telomerase activity	Biological process	16545136
HSPA9	3313	heat shock 70kDa protein 9 (mortalin)	poly(A) RNA binding	Molecular function	22658674
MED9	55090	mediator complex subunit 9	protein binding	Molecular function	14638676
ID1	3397	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	negative regulation of DNA binding	Biological process	-
UGT2A1	10941	UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus	intracellular membrane-bounded organelle	Cellular component	-
HSP90AB1	3326	heat shock protein 90kDa alpha (cytosolic), class B member 1	mitochondrion	Cellular component	20833797
MMP13	4322	matrix metallopeptidase 13	extracellular matrix disassembly	Biological process	-
PRKCD	5580	protein kinase C, delta	innate immune response	Biological process	-
RPN1	6184	ribophorin I	cellular protein metabolic process	Biological process	-
OR6C76	390326	olfactory receptor, family 6, subfamily C, member 76	plasma membrane	Cellular component	-
ACKR3	57007	atypical chemokine receptor 3	cell adhesion	Biological process	-
F3	2152	coagulation factor III (thromboplastin, tissue factor)	extracellular space	Cellular component	19065458
AGPS	8540	alkylglycerone phosphate synthase	oxidation-reduction process	Biological process	-
ALOX15B	247	arachidonate 15-lipoxygenase, type B	nucleus	Cellular component	-
MAP2K7	5609	mitogen-activated protein kinase kinase 7	nucleus	Cellular component	-
D2HGDH	728294	D-2-hydroxyglutarate dehydrogenase	response to zinc ion	Biological process	15070399
NXF3	56000	nuclear RNA export factor 3	nucleus	Cellular component	11545741
RAB44	401258	RAB44, member RAS oncogene family	protein secretion	Biological process	-
TTLL7	79739	tubulin tyrosine ligase-like family member 7	dendrite	Cellular component	-
SYT6	148281	synaptotagmin VI	synaptic vesicle exocytosis	Biological process	-
GSTO1	9446	glutathione S-transferase omega 1	glutathione derivative biosynthetic process	Biological process	-
AADACL4	343066	arylacetamide deacetylase-like 4	integral component of membrane	Cellular component	-
HIAT1	64645	hippocampus abundant transcript 1	transporter activity	Molecular function	-
PROX1	5629	prospero homeobox 1	negative regulation of bile acid biosynthetic process	Biological process	16488887
H1FX	8971	H1 histone family, member X	DNA binding	Molecular function	-
ZBTB10	65986	zinc finger and BTB domain containing 10	regulation of transcription, DNA-templated	Biological process	-
ICAM1	3383	intercellular adhesion molecule 1	response to amphetamine	Biological process	-
LRPAP1	4043	low density lipoprotein receptor-related protein associated protein 1	low-density lipoprotein particle receptor binding	Molecular function	16263759
PIKFYVE	200576	phosphoinositide kinase, FYVE finger containing	cytoplasmic vesicle	Cellular component	-
H2AFX	3014	H2A histone family, member X	meiotic cell cycle	Biological process	-
NCBP1	4686	nuclear cap binding protein subunit 1, 80kDa	gene expression	Biological process	-
RPS27L	51065	ribosomal protein S27-like	cysteine-type endopeptidase activator activity involved in apoptotic process	Molecular function	17057733
FDFT1	2222	farnesyl-diphosphate farnesyltransferase 1	cellular lipid metabolic process	Biological process	-
RPS10	6204	ribosomal protein S10	focal adhesion	Cellular component	21423176
FBXL2	25827	F-box and leucine-rich repeat protein 2	protein binding	Molecular function	15893726
ZNF622	90441	zinc finger protein 622	Golgi apparatus	Cellular component	-
AQP5	362	aquaporin 5	odontogenesis	Biological process	12522663
ACAD9	28976	acyl-CoA dehydrogenase family, member 9	nucleus	Cellular component	21237683
SIRT1	23411	sirtuin 1	positive regulation of cAMP-dependent protein kinase activity	Biological process	18687677
CLPX	10845	caseinolytic mitochondrial matrix peptidase chaperone subunit	metal ion binding	Molecular function	-
CDK14	5218	cyclin-dependent kinase 14	plasma membrane	Cellular component	19524571
PTP4A1	7803	protein tyrosine phosphatase type IVA, member 1	endoplasmic reticulum	Cellular component	-
P2RX1	5023	purinergic receptor P2X, ligand gated ion channel, 1	purinergic nucleotide receptor activity	Molecular function	8834001
PRG3	10394	proteoglycan 3	negative regulation of translation	Biological process	10318872
GOPC	57120	golgi-associated PDZ and coiled-coil motif containing	frizzled binding	Molecular function	-
CAV1	857	caveolin 1, caveolae protein, 22kDa	regulation of membrane repolarization during action potential	Biological process	18923542
APOA5	116519	apolipoprotein A-V	regulation of intestinal cholesterol absorption	Biological process	-
ADAM19	8728	ADAM metallopeptidase domain 19	SH3 domain binding	Molecular function	-
SLC15A5	729025	solute carrier family 15, member 5	integral component of membrane	Cellular component	-
MACROD2	140733	MACRO domain containing 2	cellular response to DNA damage stimulus	Biological process	23474712
GSK3A	2931	glycogen synthase kinase 3 alpha	negative regulation of glycogen (starch) synthase activity	Biological process	19366350
RPL35	11224	ribosomal protein L35	gene expression	Biological process	-
IGHV3-23	28442	immunoglobulin heavy variable 3-23	complement activation	Biological process	-
WNK3	65267	WNK lysine deficient protein kinase 3	intracellular signal transduction	Biological process	-
IRAK1	3654	interleukin-1 receptor-associated kinase 1	kinase activity	Molecular function	12054681
MAGEA2	4101	melanoma antigen family A2	negative regulation of protein acetylation	Biological process	22117195
ADH4	127	alcohol dehydrogenase 4 (class II), pi polypeptide	alcohol catabolic process	Biological process	-
NACA	4666	nascent polypeptide-associated complex alpha subunit	regulation of transcription, DNA-templated	Biological process	-
IFNK	56832	interferon, kappa	defense response to virus	Biological process	-
LAMC2	3918	laminin, gamma 2	cell cortex	Cellular component	-
ATP10D	57205	ATPase, class V, type 10D	nucleoplasm	Cellular component	-
ADSL	158	adenylosuccinate lyase	'de novo' IMP biosynthetic process	Biological process	-
P2RX4	5025	purinergic receptor P2X, ligand gated ion channel, 4	sensory perception of pain	Biological process	14978347
SMARCA2	6595	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	chromatin remodeling	Biological process	17938176
AGO1	26523	argonaute RISC catalytic component 1	polysome	Cellular component	17932509
HSD17B3	3293	hydroxysteroid (17-beta) dehydrogenase 3	androgen biosynthetic process	Biological process	-
DGKB	1607	diacylglycerol kinase, beta 90kDa	ATP binding	Molecular function	-
SLC1A6	6511	solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6	aspartate transport	Biological process	7791878
ACSS2	55902	acyl-CoA synthetase short-chain family member 2	propionate biosynthetic process	Biological process	-
LMNB1	4001	lamin B1	lamin filament	Cellular component	-
HRC	3270	histidine rich calcium binding protein	cytosolic calcium ion homeostasis	Biological process	24125847
CDK1	983	cyclin-dependent kinase 1	protein localization to kinetochore	Biological process	18195732
NEU2	4759	sialidase 2 (cytosolic sialidase)	post-translational protein modification	Biological process	-
SLC6A15	55117	solute carrier family 6 (neutral amino acid transporter), member 15	neurotransmitter transporter activity	Molecular function	11112352
SLIT2	9353	slit homolog 2 (Drosophila)	extracellular region	Cellular component	-
TTK	7272	TTK protein kinase	protein tyrosine kinase activity	Molecular function	-
FLOT2	2319	flotillin 2	apical plasma membrane	Cellular component	23983584
IFT172	26160	intraflagellar transport 172	dorsal/ventral pattern formation	Biological process	-
ATP7A	538	ATPase, Cu++ transporting, alpha polypeptide	brush border membrane	Cellular component	-
DTL	51514	denticleless E3 ubiquitin protein ligase homolog (Drosophila)	response to UV	Biological process	18794347
ACADL	33	acyl-CoA dehydrogenase, long chain	fatty acid beta-oxidation	Biological process	-
VAV3	10451	vav 3 guanine nucleotide exchange factor	blood coagulation	Biological process	-
FAU	2197	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed	cytosolic small ribosomal subunit	Cellular component	15883184
OR10H2	26538	olfactory receptor, family 10, subfamily H, member 2	olfactory receptor activity	Molecular function	-
RCAN2	10231	regulator of calcineurin 2	short-term memory	Biological process	-
FBXO45	200933	F-box protein 45	anterior commissure morphogenesis	Biological process	-
GABRG2	2566	gamma-aminobutyric acid (GABA) A receptor, gamma 2	transport	Biological process	2538761
PHF1	5252	PHD finger protein 1	cytoplasm	Cellular component	-
GBA3	57733	glucosidase, beta, acid 3 (gene/pseudogene)	glycoside catabolic process	Biological process	11389701
HIST1H1C	3006	histone cluster 1, H1c	protein binding	Molecular function	22720776
FETUB	26998	fetuin B	cysteine-type endopeptidase inhibitor activity	Molecular function	-
ACP5	54	acid phosphatase 5, tartrate resistant	negative regulation of nitric oxide biosynthetic process	Biological process	-
FKBP7	51661	FK506 binding protein 7	endoplasmic reticulum lumen	Cellular component	-
CBLB	868	Cbl proto-oncogene B, E3 ubiquitin protein ligase	protein binding	Molecular function	10022120
BEST2	54831	bestrophin 2	sensory perception of smell	Biological process	-
REC8	9985	REC8 meiotic recombination protein	nucleus	Cellular component	10207075
TTLL9	164395	tubulin tyrosine ligase-like family member 9	cytoplasm	Cellular component	-
PROS1	5627	protein S (alpha)	proteolysis	Biological process	-
ATXN10	25814	ataxin 10	extracellular space	Cellular component	23580065
ZFAND5	7763	zinc finger, AN1-type domain 5	zinc ion binding	Molecular function	-
NPM1	4869	nucleophosmin (nucleolar phosphoprotein B23, numatrin)	nucleocytoplasmic transport	Biological process	12080348
NCALD	83988	neurocalcin delta	regulation of systemic arterial blood pressure	Biological process	-
ENDOG	2021	endonuclease G	apoptotic DNA fragmentation	Biological process	-
VANGL2	57216	VANGL planar cell polarity protein 2	lateral plasma membrane	Cellular component	-
SYNGR1	9145	synaptogyrin 1	regulation of long-term neuronal synaptic plasticity	Biological process	-
SP1	6667	Sp1 transcription factor	DNA binding	Molecular function	12560508
NRARP	441478	NOTCH-regulated ankyrin repeat protein	blood vessel endothelial cell proliferation involved in sprouting angiogenesis	Biological process	-
SEMA6B	10501	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B	cell differentiation	Biological process	-
PPM1F	9647	protein phosphatase, Mg2+/Mn2+ dependent, 1F	positive regulation of focal adhesion assembly	Biological process	20016286
KCNIP4	80333	Kv channel interacting protein 4	neuronal cell body	Cellular component	-
TFAP2A	7020	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	chromatin binding	Molecular function	-
YARS2	51067	tyrosyl-tRNA synthetase 2, mitochondrial	tyrosine binding	Molecular function	17997975
GSN	2934	gelsolin	amyloid fibril formation	Biological process	19904968
RHBDD1	84236	rhomboid domain containing 1	mitochondrion	Cellular component	-
CHRNA10	57053	cholinergic receptor, nicotinic, alpha 10 (neuronal)	calcium ion transmembrane transport	Biological process	-
NEUROG3	50674	neurogenin 3	transcription coactivator activity	Molecular function	-
SLC25A18	83733	solute carrier family 25 (glutamate carrier), member 18	transmembrane transport	Biological process	-
SLC26A1	10861	solute carrier family 26 (anion exchanger), member 1	sulfate transport	Biological process	-
NDN	4692	necdin, melanoma antigen (MAGE) family member	regulation of transcription, DNA-templated	Biological process	-
CCBL1	883	cysteine conjugate-beta lyase, cytoplasmic	kynurenine-oxoglutarate transaminase activity	Molecular function	19338303
DKK4	27121	dickkopf WNT signaling pathway inhibitor 4	extracellular region	Cellular component	-
ERCC1	2067	excision repair cross-complementation group 1	post-embryonic hemopoiesis	Biological process	-
RAB24	53917	RAB24, member RAS oncogene family	GTP binding	Molecular function	-
NR0B1	190	nuclear receptor subfamily 0, group B, member 1	nucleoplasm	Cellular component	-
ECM1	1893	extracellular matrix protein 1	biomineral tissue development	Biological process	-
ZNF263	10127	zinc finger protein 263	transcription, DNA-templated	Biological process	-
GAS1	2619	growth arrest-specific 1	dorsal/ventral neural tube patterning	Biological process	-
CD9	928	CD9 molecule	fusion of sperm to egg plasma membrane	Biological process	-
HSPA8	3312	heat shock 70kDa protein 8	axon guidance	Biological process	-
PBX4	80714	pre-B-cell leukemia homeobox 4	sequence-specific DNA binding	Molecular function	11335119
SENP3	26168	SUMO1/sentrin/SMT3 specific peptidase 3	nucleus	Cellular component	-
TFAP2E	339488	transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)	protein homodimerization activity	Molecular function	-
CYP11B2	1585	cytochrome P450, family 11, subfamily B, polypeptide 2	aldosterone biosynthetic process	Biological process	19342457
SLC39A4	55630	solute carrier family 39 (zinc transporter), member 4	cellular response to zinc ion starvation	Biological process	-
OR5A2	219981	olfactory receptor, family 5, subfamily A, member 2	olfactory receptor activity	Molecular function	-
RNASE3	6037	ribonuclease, RNase A family, 3	ribonuclease activity	Molecular function	2745977
IL4	3565	interleukin 4	T-helper 2 cell cytokine production	Biological process	20554961
HTT	3064	huntingtin	p53 binding	Molecular function	10823891
DLL4	54567	delta-like 4 (Drosophila)	positive regulation of gene expression	Biological process	23388056
DZIP1L	199221	DAZ interacting zinc finger protein 1-like	centriole	Cellular component	19852954
PDXP	57026	pyridoxal (pyridoxine, vitamin B6) phosphatase	pyridoxal phosphatase activity	Molecular function	-
MAT2A	4144	methionine adenosyltransferase II, alpha	protein binding	Molecular function	10644686
EDA2R	60401	ectodysplasin A2 receptor	positive regulation of NF-kappaB transcription factor activity	Biological process	11039935
FMO4	2329	flavin containing monooxygenase 4	flavin adenine dinucleotide binding	Molecular function	-
CCKBR	887	cholecystokinin B receptor	cytosol	Cellular component	10913157
CCND1	595	cyclin D1	fat cell differentiation	Biological process	-
ADAM8	101	ADAM metallopeptidase domain 8	tertiary granule	Cellular component	17548643
TGFB1	7040	transforming growth factor, beta 1	response to wounding	Biological process	18040277
COL4A4	1286	collagen, type IV, alpha 4	extracellular matrix structural constituent	Molecular function	17942953
ALYREF	10189	Aly/REF export factor	nuclear speck	Cellular component	-
HK1	3098	hexokinase 1	glucose metabolic process	Biological process	-
ISCA1	81689	iron-sulfur cluster assembly 1	iron-sulfur cluster assembly	Biological process	-
OFD1	8481	oral-facial-digital syndrome 1	axoneme assembly	Biological process	-
HIST1H1D	3007	histone cluster 1, H1d	nuclear chromatin	Cellular component	19882353
KAAG1	353219	kidney associated antigen 1	immune response	Biological process	10601354
GNA12	2768	guanine nucleotide binding protein (G protein) alpha 12	GTPase activity	Molecular function	-
NLGN4X	57502	neuroligin 4, X-linked	brainstem development	Biological process	18227507
PTGDS	5730	prostaglandin D2 synthase 21kDa (brain)	response to glucocorticoid	Biological process	-
MECOM	2122	MDS1 and EVI1 complex locus	inflammatory response	Biological process	-
CREB1	1385	cAMP responsive element binding protein 1	secretory granule organization	Biological process	-
OMA1	115209	OMA1 zinc metallopeptidase	energy homeostasis	Biological process	22433842
CCT2	10576	chaperonin containing TCP1, subunit 2 (beta)	ATP binding	Molecular function	-
HEATR1	55127	HEAT repeat containing 1	snoRNA binding	Molecular function	-
PHF8	23133	PHD finger protein 8	mitotic cell cycle	Biological process	-
BARD1	580	BRCA1 associated RING domain 1	RNA binding	Molecular function	12419249
PRICKLE2	166336	prickle homolog 2 (Drosophila)	cytoplasm	Cellular component	-
NKX6-1	4825	NK6 homeobox 1	endocrine pancreas development	Biological process	-
PLVAP	83483	plasmalemma vesicle associated protein	MAPK cascade	Biological process	15155804
MYO9B	4650	myosin IXB	ATPase activity	Molecular function	16338935
MZB1	51237	marginal zone B and B1 cell-specific protein	regulation of B cell proliferation	Biological process	-
MEN1	4221	multiple endocrine neoplasia I	positive regulation of transforming growth factor beta receptor signaling pathway	Biological process	11274402
ALDOA	226	aldolase A, fructose-bisphosphate	blood coagulation	Biological process	-
SKP2	6502	S-phase kinase-associated protein 2, E3 ubiquitin protein ligase	aggresome	Cellular component	-
LCK	3932	LCK proto-oncogene, Src family tyrosine kinase	leukocyte migration	Biological process	-
CANX	821	calnexin	protein binding	Molecular function	16361248
ATF7IP	55729	activating transcription factor 7 interacting protein	cytoplasm	Cellular component	-
KCNA1	3736	potassium channel, voltage gated shaker related subfamily A, member 1	voltage-gated potassium channel activity	Molecular function	19912772
DUT	1854	deoxyuridine triphosphatase	cytoplasm	Cellular component	-
EPS8L1	54869	EPS8-like 1	ruffle membrane	Cellular component	14565974
KCNK4	50801	potassium channel, two pore domain subfamily K, member 4	potassium channel complex	Cellular component	22282805
GALR2	8811	galanin receptor 2	integral component of membrane	Cellular component	-
NFIC	4782	nuclear factor I/C (CCAAT-binding transcription factor)	DNA replication	Biological process	-
BATF3	55509	basic leucine zipper transcription factor, ATF-like 3	negative regulation of transcription from RNA polymerase II promoter	Biological process	15467742
FAM209B	388799	family with sequence similarity 209, member B	nucleus	Cellular component	21630459
HCN2	610	hyperpolarization activated cyclic nucleotide gated potassium channel 2	plasma membrane	Cellular component	-
PATL1	219988	protein associated with topoisomerase II homolog 1 (yeast)	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	Biological process	-
NSMAF	8439	neutral sphingomyelinase (N-SMase) activation associated factor	endomembrane system	Cellular component	-
GTF2B	2959	general transcription factor IIB	nucleus	Cellular component	-
WNT8B	7479	wingless-type MMTV integration site family, member 8B	proteinaceous extracellular matrix	Cellular component	-
NUDCD1	84955	NudC domain containing 1	nucleoplasm	Cellular component	-
BCORL1	63035	BCL6 corepressor-like 1	cytoplasm	Cellular component	-
RAD9A	5883	RAD9 homolog A (S. pombe)	3'-5' exonuclease activity	Molecular function	10713044
DNAJB1	3337	DnaJ (Hsp40) homolog, subfamily B, member 1	chaperone cofactor-dependent protein refolding	Biological process	18620420
CITED1	4435	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1	negative regulation of neuron apoptotic process	Biological process	21172805
MOB4	25843	MOB family member 4, phocein	neuronal cell body	Cellular component	-
PC	5091	pyruvate carboxylase	negative regulation of gene expression	Biological process	23861867
OSR1	130497	odd-skipped related transciption factor 1	renal vesicle progenitor cell differentiation	Biological process	-
BAK1	578	BCL2-antagonist/killer 1	negative regulation of gene expression	Biological process	-
SLC9A2	6549	solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2	transmembrane transport	Biological process	-
MEP1B	4225	meprin A, beta	inflammatory response	Biological process	-
TAF11	6882	TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa	RNA polymerase II transcriptional preinitiation complex assembly	Biological process	-
CTHRC1	115908	collagen triple helix repeat containing 1	positive regulation of protein binding	Biological process	-
DLL1	28514	delta-like 1 (Drosophila)	positive regulation of Notch signaling pathway	Biological process	-
GRM7	2917	glutamate receptor, metabotropic 7	glutamate binding	Molecular function	9144652
CPN2	1370	carboxypeptidase N, polypeptide 2	extracellular exosome	Cellular component	23376485
PRDX5	25824	peroxiredoxin 5	gene expression	Biological process	-
PARK7	11315	parkinson protein 7	copper ion binding	Molecular function	23792957
MYH4	4622	myosin, heavy chain 4, skeletal muscle	calmodulin binding	Molecular function	-
NEUROD6	63974	neuronal differentiation 6	transcription, DNA-templated	Biological process	-
NOS1AP	9722	nitric oxide synthase 1 (neuronal) adaptor protein	sarcolemma	Cellular component	18337493
KCTD12	115207	potassium channel tetramerization domain containing 12	receptor complex	Cellular component	-
DPP9	91039	dipeptidyl-peptidase 9	proteolysis	Biological process	-
LILRB3	11025	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	negative regulation of osteoclast differentiation	Biological process	18802077
NPR2	4882	natriuretic peptide receptor 2	transmembrane signaling receptor activity	Molecular function	1327579
ENOX1	55068	ecto-NOX disulfide-thiol exchanger 1	plasma membrane	Cellular component	-
SMAD3	4088	SMAD family member 3	positive regulation of stress fiber assembly	Biological process	-
RAB1A	5861	RAB1A, member RAS oncogene family	positive regulation of glycoprotein metabolic process	Biological process	21680502
GZMB	3002	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	serine-type peptidase activity	Molecular function	2402757
MAB21L2	10586	mab-21-like 2 (C. elegans)	eye development	Biological process	24906020
FAM65A	79567	family with sequence similarity 65, member A	extracellular exosome	Cellular component	19056867
VPS11	55823	vacuolar protein sorting 11 homolog (S. cerevisiae)	positive regulation of early endosome to late endosome transport	Biological process	21148287
OXT	5020	oxytocin/neurophysin I prepropeptide	male mating behavior	Biological process	-
JUND	3727	jun D proto-oncogene	nucleoplasm	Cellular component	-
IWS1	55677	IWS1 homolog (S. cerevisiae)	regulation of mRNA export from nucleus	Biological process	17234882
IL10	3586	interleukin 10	positive regulation of JAK-STAT cascade	Biological process	-
UBE2C	11065	ubiquitin-conjugating enzyme E2C	protein binding	Molecular function	19822757
USP6	9098	ubiquitin specific peptidase 6	protein deubiquitination	Biological process	16127172
TERF2IP	54386	telomeric repeat binding factor 2, interacting protein	nucleus	Cellular component	-
MRPL53	116540	mitochondrial ribosomal protein L53	ribosome	Cellular component	-
ZSCAN2	54993	zinc finger and SCAN domain containing 2	multicellular organismal development	Biological process	-
ZNF134	7693	zinc finger protein 134	regulation of transcription, DNA-templated	Biological process	7557990
CST5	1473	cystatin D	extracellular exosome	Cellular component	19199708
TXNRD3	114112	thioredoxin reductase 3	spermatogenesis	Biological process	-
ARHGAP5	394	Rho GTPase activating protein 5	cytoplasm	Cellular component	8537347
PACSIN2	11252	protein kinase C and casein kinase substrate in neurons 2	membrane tubulation	Biological process	-
SIX1	6495	SIX homeobox 1	regulation of satellite cell proliferation	Biological process	-
RERGL	79785	RERG/RAS-like	intracellular	Cellular component	-
AGO2	27161	argonaute RISC catalytic component 2	cytoplasm	Cellular component	15260970
MYH7B	57644	myosin, heavy chain 7B, cardiac muscle, beta	protein binding	Molecular function	23455924
TNFRSF10B	8795	tumor necrosis factor receptor superfamily, member 10b	regulation of apoptotic process	Biological process	10549288
CCR3	1232	chemokine (C-C motif) receptor 3	cellular defense response	Biological process	10713092
ZNF720	124411	zinc finger protein 720	regulation of transcription, DNA-templated	Biological process	-
OPN1LW	5956	opsin 1 (cone pigments), long-wave-sensitive	retinoid metabolic process	Biological process	-
XBP1	7494	X-box binding protein 1	ATF6-mediated unfolded protein response	Biological process	-
CD44	960	CD44 molecule (Indian blood group)	negative regulation of apoptotic process	Biological process	19047049
GRAP2	9402	GRB2-related adaptor protein 2	cell-cell signaling	Biological process	9878555
RBFOX2	23543	RNA binding protein, fox-1 homolog (C. elegans) 2	regulation of cell proliferation	Biological process	11875103
MAPK8	5599	mitogen-activated protein kinase 8	toll-like receptor 2 signaling pathway	Biological process	-
MAP3K3	4215	mitogen-activated protein kinase kinase kinase 3	MAPK cascade	Biological process	9006902
EARS2	124454	glutamyl-tRNA synthetase 2, mitochondrial	mitochondrion	Cellular component	19805282
ADAMTS5	11096	ADAM metallopeptidase with thrombospondin type 1 motif, 5	protein binding	Molecular function	22406378
GPC5	2262	glypican 5	chondroitin sulfate metabolic process	Biological process	-
CDV3	55573	CDV3 homolog (mouse)	plasma membrane	Cellular component	-
GNA13	10672	guanine nucleotide binding protein (G protein), alpha 13	D5 dopamine receptor binding	Molecular function	-
NOL8	55035	nucleolar protein 8	nucleus	Cellular component	-
BCAR3	8412	breast cancer anti-estrogen resistance 3	lens morphogenesis in camera-type eye	Biological process	-
NPNT	255743	nephronectin	extracellular exosome	Cellular component	19199708
SYT8	90019	synaptotagmin VIII	calcium-dependent protein binding	Molecular function	-
YWHAB	7529	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta	membrane organization	Biological process	-
NPPB	4879	natriuretic peptide B	extracellular region	Cellular component	14960748
ERCC2	2068	excision repair cross-complementation group 2	positive regulation of transcription from RNA polymerase II promoter	Biological process	8692841
CLIC6	54102	chloride intracellular channel 6	regulation of ion transmembrane transport	Biological process	-
TYMS	7298	thymidylate synthetase	cytosol	Cellular component	-
TICAM1	148022	toll-like receptor adaptor molecule 1	lipopolysaccharide-mediated signaling pathway	Biological process	-
IKBKE	9641	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	negative regulation of type I interferon production	Biological process	-
TBL1X	6907	transducin (beta)-like 1X-linked	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological process	-
SLC1A7	6512	solute carrier family 1 (glutamate transporter), member 7	sodium:dicarboxylate symporter activity	Molecular function	-
UTS2	10911	urotensin 2	negative regulation of renal sodium excretion	Biological process	-
NDP	4693	Norrie disease (pseudoglioma)	signal transduction	Biological process	8298646
FSTL3	10272	follistatin-like 3 (secreted glycoprotein)	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	Biological process	17878677
SOX8	30812	SRY (sex determining region Y)-box 8	oligodendrocyte differentiation	Biological process	-
APOA4	337	apolipoprotein A-IV	very-low-density lipoprotein particle remodeling	Biological process	2307668
IARS2	55699	isoleucyl-tRNA synthetase 2, mitochondrial	isoleucine-tRNA ligase activity	Molecular function	-
IFIT1	3434	interferon-induced protein with tetratricopeptide repeats 1	negative regulation of helicase activity	Biological process	19008854
RPS6KA2	6196	ribosomal protein S6 kinase, 90kDa, polypeptide 2	nucleus	Cellular component	-
ACD	65057	adrenocortical dysplasia homolog (mouse)	cytoplasm	Cellular component	-
RET	5979	ret proto-oncogene	positive regulation of cell size	Biological process	-
SCARA5	286133	scavenger receptor class A, member 5	cellular iron ion homeostasis	Biological process	-
RB1	5925	retinoblastoma 1	neuron maturation	Biological process	-
MMD2	221938	monocyte to macrophage differentiation-associated 2	perinuclear region of cytoplasm	Cellular component	22500632
TTC8	123016	tetratricopeptide repeat domain 8	multicellular organism growth	Biological process	-
SNAI1	6615	snail family zinc finger 1	trophoblast giant cell differentiation	Biological process	-
ARL2	402	ADP-ribosylation factor-like 2	positive regulation of microtubule polymerization	Biological process	10831612
POLE	5426	polymerase (DNA directed), epsilon, catalytic subunit	nucleoplasm	Cellular component	-
MS4A8	83661	membrane-spanning 4-domains, subfamily A, member 8	integral component of membrane	Cellular component	-
DUSP21	63904	dual specificity phosphatase 21	MAP kinase tyrosine/serine/threonine phosphatase activity	Molecular function	-
VMP1	81671	vacuole membrane protein 1	exocytosis	Biological process	-
ISG20	3669	interferon stimulated exonuclease gene 20kDa	Cajal body	Cellular component	16514659
SCN5A	6331	sodium channel, voltage gated, type V alpha subunit	regulation of atrial cardiac muscle cell membrane depolarization	Biological process	19167345
LYVE1	10894	lymphatic vessel endothelial hyaluronan receptor 1	movement of cell or subcellular component	Biological process	10037799
HILS1	373861	histone linker H1 domain, spermatid-specific 1, pseudogene	histone binding	Molecular function	12920187
SEC23A	10484	Sec23 homolog A (S. cerevisiae)	COPII vesicle coating	Biological process	-
SMCO3	440087	single-pass membrane protein with coiled-coil domains 3	protein binding	Molecular function	25416956
ACVRL1	94	activin A receptor type II-like 1	activin binding	Molecular function	8242742
RAB40AL	282808	RAB40A, member RAS oncogene family-like	cytoplasm	Cellular component	22581972
GLI3	2737	GLI family zinc finger 3	smoothened signaling pathway involved in dorsal/ventral neural tube patterning	Biological process	-
UBE2S	27338	ubiquitin-conjugating enzyme E2S	protein K29-linked ubiquitination	Biological process	20061386
DYNC1H1	1778	dynein, cytoplasmic 1, heavy chain 1	microtubule-based movement	Biological process	-
SPHK2	56848	sphingosine kinase 2	sphingolipid metabolic process	Biological process	-
COX6B2	125965	cytochrome c oxidase subunit VIb polypeptide 2 (testis)	mitochondrial crista	Cellular component	12874793
APOBEC3H	164668	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H	innate immune response	Biological process	-
PCP4	5121	Purkinje cell protein 4	nucleus	Cellular component	16780588
CAMSAP3	57662	calmodulin regulated spectrin-associated protein family, member 3	regulation of organelle organization	Biological process	23169647
KLKP1	606293	kallikrein pseudogene 1	nucleus	Cellular component	-
MAGEA8	4107	melanoma antigen family A8	cellular_component	Cellular component	-
CARD11	84433	caspase recruitment domain family, member 11	Fc-epsilon receptor signaling pathway	Biological process	-
ADAP2	55803	ArfGAP with dual PH domains 2	heart development	Biological process	16138909
PPP2CB	5516	protein phosphatase 2, catalytic subunit, beta isozyme	fibroblast growth factor receptor signaling pathway	Biological process	-
FGFR3	2261	fibroblast growth factor receptor 3	positive regulation of protein ubiquitination	Biological process	-
TUT1	64852	terminal uridylyl transferase 1, U6 snRNA-specific	nuclear speck	Cellular component	18288197
UBXN2A	165324	UBX domain protein 2A	regulation of protein catabolic process	Biological process	-
NBN	4683	nibrin	mitotic G2 DNA damage checkpoint	Biological process	11438675
TNFRSF21	27242	tumor necrosis factor receptor superfamily, member 21	protein binding	Molecular function	19225519
HCN2	610	hyperpolarization activated cyclic nucleotide gated potassium channel 2	regulation of membrane potential	Biological process	22748890
MRPS36	92259	mitochondrial ribosomal protein S36	mitochondrial translational initiation	Biological process	-
CHRNB2	1141	cholinergic receptor, nicotinic, beta 2 (neuronal)	positive regulation of B cell proliferation	Biological process	-
SCIMP	388325	SLP adaptor and CSK interacting membrane protein	uropod membrane	Cellular component	21930792
ZNF35	7584	zinc finger protein 35	sequence-specific DNA binding transcription factor activity	Molecular function	1572646
PSMB2	5690	proteasome (prosome, macropain) subunit, beta type, 2	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
MAN2A1	4124	mannosidase, alpha, class 2A, member 1	zinc ion binding	Molecular function	-
WEE1	7465	WEE1 G2 checkpoint kinase	blood coagulation	Biological process	-
H2AFV	94239	H2A histone family, member V	nucleosome	Cellular component	-
RC3H1	149041	ring finger and CCCH-type domains 1	mRNA 3'-UTR binding	Molecular function	-
ZNF22	7570	zinc finger protein 22	regulation of transcription, DNA-templated	Biological process	14630903
CAV2	858	caveolin 2	receptor-mediated endocytosis of virus by host cell	Biological process	21047970
DOLPP1	57171	dolichyldiphosphatase 1	integral component of endoplasmic reticulum membrane	Cellular component	-
DVL2	1856	dishevelled segment polarity protein 2	cytoplasm	Cellular component	23209302
RASGRP3	25780	RAS guanyl releasing protein 3 (calcium and DAG-regulated)	positive regulation of GTPase activity	Biological process	-
NEK6	10783	NIMA-related kinase 6	protein serine/threonine kinase activity	Molecular function	14563848
SOD1	6647	superoxide dismutase 1, soluble	removal of superoxide radicals	Biological process	-
NCBP2	22916	nuclear cap binding protein subunit 2, 20kDa	mRNA splicing, via spliceosome	Biological process	-
MED18	54797	mediator complex subunit 18	regulation of transcription from RNA polymerase II promoter	Biological process	-
HSP90AA1	3320	heat shock protein 90kDa alpha (cytosolic), class A member 1	mRNA binding	Molecular function	-
GLI2	2736	GLI family zinc finger 2	motile primary cilium	Cellular component	-
SELPLG	6404	selectin P ligand	membrane	Cellular component	7505206
WDR34	89891	WD repeat domain 34	primary cilium	Cellular component	-
ZP2	7783	zona pellucida glycoprotein 2 (sperm receptor)	prevention of polyspermy	Biological process	22472438
IRF2BP1	26145	interferon regulatory factor 2 binding protein 1	regulation of transcription, DNA-templated	Biological process	-
RCOR3	55758	REST corepressor 3	chromatin binding	Molecular function	-
ELANE	1991	elastase, neutrophil expressed	endopeptidase activity	Molecular function	12887060
ENTPD8	377841	ectonucleoside triphosphate diphosphohydrolase 8	nucleoside-triphosphatase activity	Molecular function	-
MRLN	100507027	myoregulin	negative regulation of catalytic activity	Biological process	-
RPS26	6231	ribosomal protein S26	mRNA binding	Molecular function	15716004
PHF11	51131	PHD finger protein 11	transcription, DNA-templated	Biological process	-
SLC7A13	157724	solute carrier family 7 (anionic amino acid transporter), member 13	antiporter activity	Molecular function	-
LGR4	55366	leucine-rich repeat containing G protein-coupled receptor 4	epithelial cell proliferation	Biological process	-
MARCKS	4082	myristoylated alanine-rich protein kinase C substrate	protein kinase C binding	Molecular function	-
HDAC1	3065	histone deacetylase 1	transcription, DNA-templated	Biological process	-
EPHX2	2053	epoxide hydrolase 2, cytoplasmic	cytosol	Cellular component	-
PTK6	5753	protein tyrosine kinase 6	ATP binding	Molecular function	-
GSTM3	2947	glutathione S-transferase mu 3 (brain)	response to estrogen	Biological process	10037815
USP14	9097	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)	regulation of proteasomal protein catabolic process	Biological process	18162577
NEFH	4744	neurofilament, heavy polypeptide	microtubule cytoskeleton organization	Biological process	-
DDIAS	220042	DNA damage-induced apoptosis suppressor	cellular response to gamma radiation	Biological process	-
DACT1	51339	dishevelled-binding antagonist of beta-catenin 1	positive regulation of catenin import into nucleus	Biological process	15580286
LAMP2	3920	lysosomal-associated membrane protein 2	membrane	Cellular component	15297306
MAP3K12	7786	mitogen-activated protein kinase kinase kinase 12	cytoplasm	Cellular component	8663324
LPL	4023	lipoprotein lipase	triglyceride metabolic process	Biological process	10727238
ADAM9	8754	ADAM metallopeptidase domain 9	cell-matrix adhesion	Biological process	15361064
GBA2	57704	glucosidase, beta (bile acid) 2	integral component of membrane	Cellular component	11489889
SLC1A3	6507	solute carrier family 1 (glial high affinity glutamate transporter), member 3	neuromuscular process controlling balance	Biological process	-
BBS10	79738	Bardet-Biedl syndrome 10	photoreceptor cell maintenance	Biological process	17980398
DSG3	1830	desmoglein 3	desmosome	Cellular component	-
ANGPTL3	27329	angiopoietin-like 3	response to hormone	Biological process	-
RNF139	11236	ring finger protein 139	endoplasmic reticulum membrane	Cellular component	-
EPGN	255324	epithelial mitogen	activation of MAPK activity	Biological process	-
MED12	9968	mediator complex subunit 12	stem cell maintenance	Biological process	-
DDX24	57062	DEAD (Asp-Glu-Ala-Asp) box helicase 24	poly(A) RNA binding	Molecular function	22658674
P2RX3	5024	purinergic receptor P2X, ligand gated ion channel, 3	signal transduction	Biological process	9221902
HSH2D	84941	hematopoietic SH2 domain containing	negative regulation of B cell apoptotic process	Biological process	-
NFKB1	4790	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	negative regulation of apoptotic process	Biological process	10811897
METTL25	84190	methyltransferase like 25	methyltransferase activity	Molecular function	-
RAP1GDS1	5910	RAP1, GTP-GDP dissociation stimulator 1	mitochondrion	Cellular component	24349085
COA5	493753	cytochrome c oxidase assembly factor 5	mitochondrion	Cellular component	-
CCBL2	56267	cysteine conjugate-beta lyase 2	biosynthetic process	Biological process	-
TTN	7273	titin	cardiac myofibril assembly	Biological process	11846417
IDO1	3620	indoleamine 2,3-dioxygenase 1	heme binding	Molecular function	-
PRM1	5619	protamine 1	nucleoplasm	Cellular component	2081589
FGD2	221472	FYVE, RhoGEF and PH domain containing 2	cytoskeleton	Cellular component	-
CNFN	84518	cornifelin	keratinization	Biological process	-
ZNF419	79744	zinc finger protein 419	regulation of transcription, DNA-templated	Biological process	-
HNRNPU	3192	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	cell surface	Cellular component	-
STX1B	112755	syntaxin 1B	nucleus	Cellular component	-
PTPN3	5774	protein tyrosine phosphatase, non-receptor type 3	negative regulation of mitotic cell cycle	Biological process	10364224
TEX11	56159	testis expressed 11	synaptonemal complex	Cellular component	-
PARP12	64761	poly (ADP-ribose) polymerase family, member 12	metal ion binding	Molecular function	-
ITGB3	3690	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	integrin-mediated signaling pathway	Biological process	21488147
DDX52	11056	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52	membrane	Cellular component	19946888
RBM4B	83759	RNA binding motif protein 4B	entrainment of circadian clock by photoperiod	Biological process	-
IFNA13	3447	interferon, alpha 13	cytokine activity	Molecular function	-
ZNF546	339327	zinc finger protein 546	sequence-specific DNA binding transcription factor activity	Molecular function	-
SAA1	6288	serum amyloid A1	positive regulation of cytosolic calcium ion concentration	Biological process	7561109
CYP4A11	1579	cytochrome P450, family 4, subfamily A, polypeptide 11	alkane 1-monooxygenase activity	Molecular function	18433732
PPP5C	5536	protein phosphatase 5, catalytic subunit	neuronal cell body	Cellular component	-
MAEL	84944	maelstrom spermatogenic transposon silencer	gene silencing by RNA	Biological process	-
RSF1	51773	remodeling and spacing factor 1	nucleus	Cellular component	-
CDK5	1020	cyclin-dependent kinase 5	peptidyl-threonine phosphorylation	Biological process	-
RPS27A	6233	ribosomal protein S27a	viral protein processing	Biological process	-
TGFB1	7040	transforming growth factor, beta 1	protein N-terminus binding	Molecular function	-
FZD4	8322	frizzled class receptor 4	Wnt signaling pathway, calcium modulating pathway	Biological process	12172548
SAMD11	148398	sterile alpha motif domain containing 11	protein self-association	Molecular function	-
JCHAIN	3512	joining chain of multimeric IgA and IgM	pentameric IgM immunoglobulin complex	Cellular component	21786026
ZNF790	388536	zinc finger protein 790	DNA binding	Molecular function	-
HSF1	3297	heat shock transcription factor 1	negative regulation of cell proliferation	Biological process	-
HIST1H2BD	3017	histone cluster 1, H2bd	nucleoplasm	Cellular component	-
BRSK2	9024	BR serine/threonine kinase 2	protein kinase binding	Molecular function	-
AVPR2	554	arginine vasopressin receptor 2	adenylate cyclase-modulating G-protein coupled receptor signaling pathway	Biological process	10880054
DSG1	1828	desmoglein 1	cellular component disassembly involved in execution phase of apoptosis	Biological process	-
NRP2	8828	neuropilin 2	heparin binding	Molecular function	-
EWSR1	2130	EWS RNA-binding protein 1	plasma membrane	Cellular component	-
BEGAIN	57596	brain-enriched guanylate kinase-associated	protein binding	Molecular function	16189514
ZNF346	23567	zinc finger protein 346	enzyme binding	Molecular function	23382074
CSDC2	27254	cold shock domain containing C2, RNA binding	protein binding	Molecular function	25416956
MYH3	4621	myosin, heavy chain 3, skeletal muscle, embryonic	extracellular exosome	Cellular component	19056867
EHD1	10938	EH-domain containing 1	protein homooligomerization	Biological process	17233914
LRRK2	120892	leucine-rich repeat kinase 2	negative regulation of protein phosphorylation	Biological process	-
RPS13	6207	ribosomal protein S13	ribosome	Cellular component	8332508
ZEB1	6935	zinc finger E-box binding homeobox 1	immune response	Biological process	1840704
BAG1	573	BCL2-associated athanogene	cellular response to heat	Biological process	-
CFTR	1080	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	bicarbonate transport	Biological process	-
OAS2	4939	2'-5'-oligoadenylate synthetase 2, 69/71kDa	cytosol	Cellular component	-
OR2A42	402317	olfactory receptor, family 2, subfamily A, member 42	plasma membrane	Cellular component	-
DNAJA3	9093	DnaJ (Hsp40) homolog, subfamily A, member 3	protein stabilization	Biological process	11927590
MRPL24	79590	mitochondrial ribosomal protein L24	mitochondrial translational initiation	Biological process	-
CETP	1071	cholesteryl ester transfer protein, plasma	triglyceride metabolic process	Biological process	2833496
AIF1L	83543	allograft inflammatory factor 1-like	ruffle membrane	Cellular component	-
PIEZO1	9780	piezo-type mechanosensitive ion channel component 1	cation channel activity	Molecular function	-
EPHA7	2045	EPH receptor A7	ephrin receptor signaling pathway	Biological process	-
ANXA11	311	annexin A11	response to calcium ion	Biological process	12601007
GAD1	2571	glutamate decarboxylase 1 (brain, 67kDa)	protein N-terminus binding	Molecular function	-
OR11H12	440153	olfactory receptor, family 11, subfamily H, member 12	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
RIPK1	8737	receptor (TNFRSF)-interacting serine-threonine kinase 1	ripoptosome	Cellular component	21737330
TRIM15	89870	tripartite motif containing 15	positive regulation of type I interferon production	Biological process	23077300
KCNC1	3746	potassium channel, voltage gated Shaw related subfamily C, member 1	potassium ion transmembrane transport	Biological process	-
GOLPH3	64083	golgi phosphoprotein 3 (coat-protein)	positive regulation of TOR signaling	Biological process	19553991
CLIC2	1193	chloride intracellular channel 2	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	Biological process	15147738
CALCA	796	calcitonin-related polypeptide alpha	negative regulation of transcription, DNA-templated	Biological process	11014233
OR12D2	26529	olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)	G-protein coupled receptor activity	Molecular function	-
RMI2	116028	RecQ mediated genome instability 2	cytoplasm	Cellular component	-
AKR1D1	6718	aldo-keto reductase family 1, member D1	cytosol	Cellular component	-
TP63	8626	tumor protein p63	nuclear chromatin	Cellular component	22521434
P2RX5	5026	purinergic receptor P2X, ligand gated ion channel, 5	positive regulation of calcium ion transport into cytosol	Biological process	17895406
APOB	338	apolipoprotein B	intermediate-density lipoprotein particle	Cellular component	1917954
PCBD2	84105	pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2	positive regulation of transcription, DNA-templated	Biological process	11980910
CENPO	79172	centromere protein O	cytosol	Cellular component	-
GP1BA	2811	glycoprotein Ib (platelet), alpha polypeptide	blood coagulation	Biological process	-
SLC16A3	9123	solute carrier family 16 (monocarboxylate transporter), member 3	actin cytoskeleton	Cellular component	-
TIMP1	7076	TIMP metallopeptidase inhibitor 1	extracellular matrix disassembly	Biological process	-
SLC22A9	114571	solute carrier family 22 (organic anion transporter), member 9	short-chain fatty acid uptake transporter activity	Molecular function	17393504
KLRG1	10219	killer cell lectin-like receptor subfamily G, member 1	regulation of immune response	Biological process	-
ATP6V0A4	50617	ATPase, H+ transporting, lysosomal V0 subunit a4	excretion	Biological process	12414817
ACVR1B	91	activin A receptor, type IB	protein phosphorylation	Biological process	12065756
RPE65	6121	retinal pigment epithelium-specific protein 65kDa	organelle membrane	Cellular component	-
ATAD1	84896	ATPase family, AAA domain containing 1	positive regulation of receptor internalization	Biological process	-
CSF3	1440	colony stimulating factor 3 (granulocyte)	cytokine-mediated signaling pathway	Biological process	15664994
OR1F1	4992	olfactory receptor, family 1, subfamily F, member 1	G-protein coupled receptor signaling pathway	Biological process	-
PRDM14	63978	PR domain containing 14	regulation of transcription, DNA-templated	Biological process	-
LPGAT1	9926	lysophosphatidylglycerol acyltransferase 1	molecular_function	Molecular function	-
LMAN2	10960	lectin, mannose-binding 2	integral component of plasma membrane	Cellular component	22016386
AOC3	8639	amine oxidase, copper containing 3	cation transport	Biological process	19764817
ZNF844	284391	zinc finger protein 844	regulation of transcription, DNA-templated	Biological process	-
PKN3	29941	protein kinase N3	ATP binding	Molecular function	-
NMB	4828	neuromedin B	glucose homeostasis	Biological process	-
CSF2RB	1439	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	interleukin-3 receptor activity	Molecular function	9410898
MTUS2	23281	microtubule associated tumor suppressor candidate 2	protein homodimerization activity	Molecular function	19543227
PDCD10	11235	programmed cell death 10	protein N-terminus binding	Molecular function	20489202
MYOZ3	91977	myozenin 3	Z disc	Cellular component	-
RPS3	6188	ribosomal protein S3	mitotic nuclear division	Biological process	-
TCF7L2	6934	transcription factor 7-like 2 (T-cell specific, HMG-box)	secretory granule localization	Biological process	-
PIK3CA	5290	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	protein phosphorylation	Biological process	-
SLC10A1	6554	solute carrier family 10 (sodium/bile acid cotransporter), member 1	small molecule metabolic process	Biological process	-
MZF1	7593	myeloid zinc finger 1	transcription regulatory region DNA binding	Molecular function	15541732
DAB2IP	153090	DAB2 interacting protein	dendrite	Cellular component	-
TSPAN4	7106	tetraspanin 4	antigen binding	Molecular function	9360996
BARX1	56033	BARX homeobox 1	cell-cell signaling	Biological process	-
LZTS1	11178	leucine zipper, putative tumor suppressor 1	cytoplasm	Cellular component	-
POMC	5443	proopiomelanocortin	receptor binding	Molecular function	9620771
HIST1H4H	8365	histone cluster 1, H4h	chromatin silencing at rDNA	Biological process	-
AMFR	267	autocrine motility factor receptor, E3 ubiquitin protein ligase	growth cone	Cellular component	-
ERBB4	2066	erb-b2 receptor tyrosine kinase 4	mammary gland alveolus development	Biological process	-
FKBP8	23770	FK506 binding protein 8, 38kDa	protein peptidyl-prolyl isomerization	Biological process	-
HCRTR2	3062	hypocretin (orexin) receptor 2	peptide binding	Molecular function	-
MBTD1	54799	mbt domain containing 1	chromatin modification	Biological process	-
CAMK2B	816	calcium/calmodulin-dependent protein kinase II beta	regulation of long-term neuronal synaptic plasticity	Biological process	18817731
JUP	3728	junction plakoglobin	adherens junction organization	Biological process	-
ITGB7	3695	integrin, beta 7	integrin alpha4-beta7 complex	Cellular component	18308860
SYT8	90019	synaptotagmin VIII	acrosomal vesicle	Cellular component	-
PSMC6	5706	proteasome (prosome, macropain) 26S subunit, ATPase, 6	proteasome accessory complex	Cellular component	-
VEGFC	7424	vascular endothelial growth factor C	angiogenesis	Biological process	-
HRH4	59340	histamine receptor H4	positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway	Biological process	-
OR2T2	401992	olfactory receptor, family 2, subfamily T, member 2	sensory perception of smell	Biological process	-
COX8A	1351	cytochrome c oxidase subunit VIIIA (ubiquitous)	protein binding	Molecular function	25416956
RUNX2	860	runt-related transcription factor 2	RNA polymerase II core promoter sequence-specific DNA binding	Molecular function	-
MKX	283078	mohawk homeobox	RNA polymerase II transcription factor binding	Molecular function	-
SIX3	6496	SIX homeobox 3	telencephalon regionalization	Biological process	-
MTSS1	9788	metastasis suppressor 1	glomerulus morphogenesis	Biological process	-
TGM2	7052	transglutaminase 2	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine	Biological process	-
NLN	57486	neurolysin (metallopeptidase M3 family)	metal ion binding	Molecular function	-
DLC1	10395	DLC1 Rho GTPase activating protein	apoptotic process	Biological process	17292327
ARHGAP6	395	Rho GTPase activating protein 6	positive regulation of signal transduction	Biological process	8570618
PON1	5444	paraoxonase 1	negative regulation of plasma lipoprotein particle oxidation	Biological process	15342686
PAXIP1	22976	PAX interacting (with transcription-activation domain) protein 1	DNA damage response, signal transduction by p53 class mediator	Biological process	15456759
SSFA2	6744	sperm specific antigen 2	cytoplasm	Cellular component	-
HSPA9	3313	heat shock 70kDa protein 9 (mortalin)	mitochondrion	Cellular component	16130169
LSM10	84967	LSM10, U7 small nuclear RNA associated	gene expression	Biological process	-
PKD2	5311	polycystic kidney disease 2 (autosomal dominant)	receptor binding	Molecular function	16223735
HTR3D	200909	5-hydroxytryptamine (serotonin) receptor 3D, ionotropic	ion transmembrane transport	Biological process	-
MLLT4	4301	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	protein C-terminus binding	Molecular function	10856295
ATP12A	479	ATPase, H+/K+ transporting, nongastric, alpha polypeptide	ATP binding	Molecular function	-
BBS5	129880	Bardet-Biedl syndrome 5	RNA polymerase II repressing transcription factor binding	Molecular function	22302990
ZMYND11	10771	zinc finger, MYND-type containing 11	negative regulation of transcription from RNA polymerase II promoter	Biological process	7621829
EREG	2069	epiregulin	positive regulation of innate immune response	Biological process	-
HDAC1	3065	histone deacetylase 1	enzyme binding	Molecular function	11062478
FGF14	2259	fibroblast growth factor 14	synaptic transmission	Biological process	-
USP20	10868	ubiquitin specific peptidase 20	cysteine-type endopeptidase activity	Molecular function	19424180
SLC1A4	6509	solute carrier family 1 (glutamate/neutral amino acid transporter), member 4	L-threonine transmembrane transporter activity	Molecular function	8340364
SOX9	6662	SRY (sex determining region Y)-box 9	negative regulation of ossification	Biological process	-
KCNIP1	30820	Kv channel interacting protein 1	voltage-gated potassium channel complex	Cellular component	10676964
KLRK1	22914	killer cell lectin-like receptor subfamily K, member 1	carbohydrate binding	Molecular function	-
SEC62	7095	SEC62 homolog (S. cerevisiae)	rough endoplasmic reticulum	Cellular component	-
S100A1	6271	S100 calcium binding protein A1	calcium-dependent protein binding	Molecular function	-
STS	412	steroid sulfatase (microsomal), isozyme S	cellular protein metabolic process	Biological process	-
COL6A5	256076	collagen, type VI, alpha 5	extracellular matrix disassembly	Biological process	-
OR4F29	729759	olfactory receptor, family 4, subfamily F, member 29	detection of chemical stimulus involved in sensory perception	Biological process	-
UGT8	7368	UDP glycosyltransferase 8	galactosylceramide biosynthetic process	Biological process	-
SORL1	6653	sortilin-related receptor, L(DLR class) A repeats containing	endosome	Cellular component	16174740
TSPO	706	translocator protein (18kDa)	response to manganese ion	Biological process	-
WWP2	11060	WW domain containing E3 ubiquitin protein ligase 2	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	-
SARDH	1757	sarcosine dehydrogenase	mitochondrial matrix	Cellular component	-
FCHO2	115548	FCH domain only 2	plasma membrane	Cellular component	-
AMER2	219287	APC membrane recruitment protein 2	ectoderm development	Biological process	-
KHK	3795	ketohexokinase (fructokinase)	cytosol	Cellular component	-
AVPR2	554	arginine vasopressin receptor 2	transmembrane transport	Biological process	-
LRRC17	10234	leucine rich repeat containing 17	bone marrow development	Biological process	-
TNPO1	3842	transportin 1	nucleus	Cellular component	-
IL15	3600	interleukin 15	cellular response to vitamin D	Biological process	-
RGCC	28984	regulator of cell cycle	positive regulation of collagen biosynthetic process	Biological process	19158077
SRMS	6725	src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites	protein tyrosine kinase activity	Molecular function	23822091
SKP1	6500	S-phase kinase-associated protein 1	cytosol	Cellular component	-
GPX4	2879	glutathione peroxidase 4	oxidation-reduction process	Biological process	9705830
LYPLA2	11313	lysophospholipase II	fatty acid metabolic process	Biological process	-
TAB1	10454	TGF-beta activated kinase 1/MAP3K7 binding protein 1	MyD88-independent toll-like receptor signaling pathway	Biological process	-
CALY	50632	calcyon neuron-specific vesicular protein	cytoplasmic vesicle	Cellular component	14534309
DTL	51514	denticleless E3 ubiquitin protein ligase homolog (Drosophila)	ubiquitin-protein transferase activity	Molecular function	18794347
FOXF1	2294	forkhead box F1	positive regulation of transcription from RNA polymerase II promoter	Biological process	8626802
FBXL19	54620	F-box and leucine-rich repeat protein 19	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological process	22660580
MEF2C	4208	myocyte enhancer factor 2C	positive regulation of MAP kinase activity	Biological process	-
ARL13B	200894	ADP-ribosylation factor-like 13B	smoothened signaling pathway	Biological process	-
RRP8	23378	ribosomal RNA processing 8, methyltransferase, homolog (yeast)	S-adenosylmethionine-dependent methyltransferase activity	Molecular function	18485871
CTH	1491	cystathionine gamma-lyase	hydrogen sulfide biosynthetic process	Biological process	19019829
FST	10468	follistatin	signal transducer activity	Molecular function	12702211
DAB1	1600	Dab, reelin signal transducer, homolog 1 (Drosophila)	dendrite development	Biological process	-
IRAK2	3656	interleukin-1 receptor-associated kinase 2	MyD88-independent toll-like receptor signaling pathway	Biological process	-
CDK5RAP1	51654	CDK5 regulatory subunit associated protein 1	protein complex binding	Molecular function	-
PARK2	5071	parkin RBR E3 ubiquitin protein ligase	response to endoplasmic reticulum stress	Biological process	21113145
NSD1	64324	nuclear receptor binding SET domain protein 1	chromatin binding	Molecular function	-
CASP14	23581	caspase 14, apoptosis-related cysteine peptidase	apoptotic process	Biological process	-
GRIK1	2897	glutamate receptor, ionotropic, kainate 1	nervous system development	Biological process	8260617
RPS25	6230	ribosomal protein S25	gene expression	Biological process	-
PRMT2	3275	protein arginine methyltransferase 2	estrogen receptor binding	Molecular function	12039952
BBOX1	8424	butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1	mitochondrion	Cellular component	-
CDK11A	728642	cyclin-dependent kinase 11A	regulation of mRNA processing	Biological process	12501247
CHRNB2	1141	cholinergic receptor, nicotinic, beta 2 (neuronal)	ligand-gated ion channel activity	Molecular function	20438829
GATAD2A	54815	GATA zinc finger domain containing 2A	in utero embryonic development	Biological process	-
LIN7C	55327	lin-7 homolog C (C. elegans)	PDZ domain binding	Molecular function	-
MED31	51003	mediator complex subunit 31	RNA polymerase II transcription cofactor activity	Molecular function	-
DAB2	1601	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)	intracellular membrane-bounded organelle	Cellular component	-
C1QBP	708	complement component 1, q subcomponent binding protein	negative regulation of interferon-gamma production	Biological process	17881511
TRBV12-3	28577	T cell receptor beta variable 12-3	T cell receptor signaling pathway	Biological process	-
BCKDHA	593	branched chain keto acid dehydrogenase E1, alpha polypeptide	protein binding	Molecular function	10745006
SLC8A1	6546	solute carrier family 8 (sodium/calcium exchanger), member 1	ion transport	Biological process	-
OR6C4	341418	olfactory receptor, family 6, subfamily C, member 4	olfactory receptor activity	Molecular function	-
ULK2	9706	unc-51 like autophagy activating kinase 2	negative regulation of collateral sprouting	Biological process	-
YBX1	4904	Y box binding protein 1	histone pre-mRNA 3'end processing complex	Cellular component	-
PLK1	5347	polo-like kinase 1	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
VARS2	57176	valyl-tRNA synthetase 2, mitochondrial	protein binding	Molecular function	25416956
FANCE	2178	Fanconi anemia, complementation group E	DNA repair	Biological process	-
ZNF254	9534	zinc finger protein 254	DNA binding	Molecular function	-
NKAP	79576	NFKB activating protein	granulocyte differentiation	Biological process	-
MKL1	57591	megakaryoblastic leukemia (translocation) 1	nucleoplasm	Cellular component	-
ARNTL	406	aryl hydrocarbon receptor nuclear translocator-like	signal transduction	Biological process	-
OSBPL9	114883	oxysterol binding protein-like 9	Golgi apparatus	Cellular component	-
GNAO1	2775	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O	positive regulation of GTPase activity	Biological process	-
EHD3	30845	EH-domain containing 3	cytoplasm	Cellular component	-
ABCD1	215	ATP-binding cassette, sub-family D (ALD), member 1	peroxisomal membrane transport	Biological process	8441467
CPLX2	10814	complexin 2	cytosol	Cellular component	-
LTC4S	4056	leukotriene C4 synthase	glutathione peroxidase activity	Molecular function	-
ATP7A	538	ATPase, Cu++ transporting, alpha polypeptide	extracellular matrix organization	Biological process	-
DEDD	9191	death effector domain containing	protein binding	Molecular function	15688372
RNF216	54476	ring finger protein 216	cytoplasm	Cellular component	-
RIC8B	55188	RIC8 guanine nucleotide exchange factor B	regulation of G-protein coupled receptor protein signaling pathway	Biological process	12652642
GPRC5B	51704	G protein-coupled receptor, class C, group 5, member B	intracellular membrane-bounded organelle	Cellular component	-
DSP	1832	desmoplakin	structural molecule activity	Molecular function	10908733
VPS11	55823	vacuolar protein sorting 11 homolog (S. cerevisiae)	regulation of organelle assembly	Biological process	21148287
ATG14	22863	autophagy related 14	axoneme	Cellular component	-
TP63	8626	tumor protein p63	transcription factor binding transcription factor activity	Molecular function	-
ACAA1	30	acetyl-CoA acyltransferase 1	cellular lipid metabolic process	Biological process	-
SNRNP25	79622	small nuclear ribonucleoprotein 25kDa (U11/U12)	mRNA processing	Biological process	-
LARGE	9215	like-glycosyltransferase	skeletal muscle tissue regeneration	Biological process	-
CARD9	64170	caspase recruitment domain family, member 9	cytoplasm	Cellular component	11053425
TRAF6	7189	TNF receptor-associated factor 6, E3 ubiquitin protein ligase	CD40 receptor complex	Cellular component	-
AGTRAP	57085	angiotensin II receptor-associated protein	endoplasmic reticulum membrane	Cellular component	-
UMOD	7369	uromodulin	cytoplasmic vesicle	Cellular component	-
COMMD10	51397	COMM domain containing 10	cytoplasm	Cellular component	-
DCN	1634	decorin	extracellular matrix binding	Molecular function	-
ERC1	23085	ELKS/RAB6-interacting/CAST family member 1	multicellular organismal development	Biological process	15218148
TMOD4	29765	tropomodulin 4 (muscle)	tropomyosin binding	Molecular function	-
OR1K1	392392	olfactory receptor, family 1, subfamily K, member 1	G-protein coupled receptor activity	Molecular function	-
CA4	762	carbonic anhydrase IV	small molecule metabolic process	Biological process	-
GUCY2F	2986	guanylate cyclase 2F, retinal	protein kinase activity	Molecular function	-
UFL1	23376	UFM1-specific ligase 1	regulation of intracellular estrogen receptor signaling pathway	Biological process	25219498
VIP	7432	vasoactive intestinal peptide	regulation of protein localization	Biological process	9603988
LCE2D	353141	late cornified envelope 2D	keratinization	Biological process	-
HIST1H3G	8355	histone cluster 1, H3g	nucleus	Cellular component	21630459
PSMC2	5701	proteasome (prosome, macropain) 26S subunit, ATPase, 2	cytoplasmic mRNA processing body	Cellular component	-
NFATC2	4773	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	B cell receptor signaling pathway	Biological process	17875758
CISH	1154	cytokine inducible SH2-containing protein	protein kinase inhibitor activity	Molecular function	-
CNTNAP5	129684	contactin associated protein-like 5	integral component of membrane	Cellular component	-
ARNT	405	aryl hydrocarbon receptor nuclear translocator	response to hypoxia	Biological process	8756616
HDAC2	3066	histone deacetylase 2	neurotrophin TRK receptor signaling pathway	Biological process	-
TXK	7294	TXK tyrosine kinase	positive regulation of transcription from RNA polymerase II promoter	Biological process	11859127
GCKR	2646	glucokinase (hexokinase 4) regulator	cytoplasm	Cellular component	-
PTTG2	10744	pituitary tumor-transforming 2	chromosome organization	Biological process	-
GALNT15	117248	polypeptide N-acetylgalactosaminyltransferase 15	transport vesicle	Cellular component	-
EXTL2	2135	exostosin-like glycosyltransferase 2	heparan sulfate proteoglycan biosynthetic process	Biological process	-
PTPN2	5771	protein tyrosine phosphatase, non-receptor type 2	negative regulation of epidermal growth factor receptor signaling pathway	Biological process	15592458
ABCG4	64137	ATP-binding cassette, sub-family G (WHITE), member 4	integral component of membrane	Cellular component	-
ERN1	2081	endoplasmic reticulum to nucleus signaling 1	protein binding	Molecular function	11278723
FBXW7	55294	F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase	regulation of mitochondrion degradation	Biological process	24912190
CAMKMT	79823	calmodulin-lysine N-methyltransferase	peptidyl-lysine methylation	Biological process	-
ATXN2	6311	ataxin 2	membrane	Cellular component	19946888
MSH3	4437	mutS homolog 3	heteroduplex DNA loop binding	Molecular function	-
PKD1L3	342372	polycystic kidney disease 1-like 3	sour taste receptor activity	Molecular function	-
GLIPR1	11010	GLI pathogenesis-related 1	small molecule metabolic process	Biological process	-
MRI1	84245	methylthioribose-1-phosphate isomerase 1	nucleolus	Cellular component	-
SMARCA2	6595	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	nucleus	Cellular component	17984088
SAP130	79595	Sin3A-associated protein, 130kDa	STAGA complex	Cellular component	11564863
RNF41	10193	ring finger protein 41, E3 ubiquitin protein ligase	protein polyubiquitination	Biological process	14765125
PRDM12	59335	PR domain containing 12	regulation of transcription from RNA polymerase II promoter	Biological process	-
CHD3	1107	chromodomain helicase DNA binding protein 3	ATP-dependent DNA helicase activity	Molecular function	9326634
VCL	7414	vinculin	actin cytoskeleton	Cellular component	-
SUPT5H	6829	suppressor of Ty 5 homolog (S. cerevisiae)	protein heterodimerization activity	Molecular function	9450929
HIF1AN	55662	hypoxia inducible factor 1, alpha subunit inhibitor	peptidyl-histidine dioxygenase activity	Molecular function	21251231
PARP3	10039	poly (ADP-ribose) polymerase family, member 3	site of double-strand break	Cellular component	21270334
AGGF1	55109	angiogenic factor with G patch and FHA domains 1	cell adhesion	Biological process	14961121
RALGPS2	55103	Ral GEF with PH domain and SH3 binding motif 2	guanyl-nucleotide exchange factor activity	Molecular function	-
PSMB2	5690	proteasome (prosome, macropain) subunit, beta type, 2	protein polyubiquitination	Biological process	-
ADGRV1	84059	adhesion G protein-coupled receptor V1	maintenance of organ identity	Biological process	15671307
DDB1	1642	damage-specific DNA binding protein 1, 127kDa	DNA damage response, detection of DNA damage	Biological process	-
MAD2L1	4085	MAD2 mitotic arrest deficient-like 1 (yeast)	negative regulation of mitotic cell cycle	Biological process	21274008
PSMB6	5694	proteasome (prosome, macropain) subunit, beta type, 6	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition	Biological process	-
CEP19	84984	centrosomal protein 19kDa	centriole	Cellular component	21399614
VEZT	55591	vezatin, adherens junctions transmembrane protein	nucleoplasm	Cellular component	-
CLDN25	644672	claudin 25	bicellular tight junction	Cellular component	-
OR2F2	135948	olfactory receptor, family 2, subfamily F, member 2	integral component of membrane	Cellular component	-
OR2J3	442186	olfactory receptor, family 2, subfamily J, member 3	plasma membrane	Cellular component	-
SIRT1	23411	sirtuin 1	positive regulation of DNA repair	Biological process	19934257
TRIM74	378108	tripartite motif containing 74	zinc ion binding	Molecular function	-
RASGRP2	10235	RAS guanyl releasing protein 2 (calcium and DAG-regulated)	ruffle membrane	Cellular component	-
GPER1	2852	G protein-coupled estrogen receptor 1	cytoplasm	Cellular component	-
APP	351	amyloid beta (A4) precursor protein	protein phosphorylation	Biological process	-
POU2F2	5452	POU class 2 homeobox 2	transcription from RNA polymerase II promoter	Biological process	9442393
CASP9	842	caspase 9, apoptosis-related cysteine peptidase	response to cobalt ion	Biological process	-
ASTE1	28990	asteroid homolog 1 (Drosophila)	nucleic acid phosphodiester bond hydrolysis	Biological process	-
GNAQ	2776	guanine nucleotide binding protein (G protein), q polypeptide	heart development	Biological process	-
INHBC	3626	inhibin, beta C	cell development	Biological process	-
TRIM23	373	tripartite motif containing 23	viral process	Biological process	-
ELMOD1	55531	ELMO/CED-12 domain containing 1	positive regulation of protein targeting to mitochondrion	Biological process	24270810
KIAA0922	23240	KIAA0922	cytoplasm	Cellular component	23690469
PNPLA8	50640	patatin-like phospholipase domain containing 8	ATP binding	Molecular function	10744668
FXYD3	5349	FXYD domain containing ion transport regulator 3	chloride transmembrane transport	Biological process	7836447
KAT8	84148	K(lysine) acetyltransferase 8	protein binding	Molecular function	11965546
ARG1	383	arginase 1	small molecule metabolic process	Biological process	-
DNA2	1763	DNA replication helicase/nuclease 2	DNA helicase activity	Molecular function	16595799
CDX1	1044	caudal type homeobox 1	nucleus	Cellular component	-
JAG1	182	jagged 1	neuronal stem cell maintenance	Biological process	19682396
ZNF861P	100302737	zinc finger protein 861, pseudogene	metal ion binding	Molecular function	-
GCNT1	2650	glucosaminyl (N-acetyl) transferase 1, core 2	kidney morphogenesis	Biological process	-
ATP5O	539	ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit	plasma membrane	Cellular component	17851741
GOSR2	9570	golgi SNAP receptor complex member 2	vesicle fusion with Golgi apparatus	Biological process	-
SLC29A2	3177	solute carrier family 29 (equilibrative nucleoside transporter), member 2	basolateral plasma membrane	Cellular component	12527552
MCC	4163	mutated in colorectal cancers	negative regulation of canonical Wnt signaling pathway	Biological process	18591935
SHOX2	6474	short stature homeobox 2	skeletal system development	Biological process	9482898
PVRL1	5818	poliovirus receptor-related 1 (herpesvirus entry mediator C)	axon guidance	Biological process	-
GRIN1	2902	glutamate receptor, ionotropic, N-methyl D-aspartate 1	axon guidance	Biological process	-
SGCA	6442	sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)	cytoskeleton	Cellular component	-
AKR1C3	8644	aldo-keto reductase family 1, member C3	intracellular	Cellular component	-
ILK	3611	integrin-linked kinase	protein kinase binding	Molecular function	19118217
TNFRSF8	943	tumor necrosis factor receptor superfamily, member 8	negative regulation of cell proliferation	Biological process	10192335
HINT1	3094	histidine triad nucleotide binding protein 1	protein kinase C binding	Molecular function	9770345
RLN3	117579	relaxin 3	G-protein coupled receptor binding	Molecular function	-
NRN1	51299	neuritin 1	nervous system development	Biological process	-
TBX1	6899	T-box 1	muscle cell fate commitment	Biological process	-
RRBP1	6238	ribosome binding protein 1	protein transport	Biological process	-
ALAD	210	aminolevulinate dehydratase	porphyrin-containing compound metabolic process	Biological process	-
PSMD7	5713	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	negative regulation of canonical Wnt signaling pathway	Biological process	-
VPS39	23339	vacuolar protein sorting 39 homolog (S. cerevisiae)	lysosomal membrane	Cellular component	17897319
LEPROT	54741	leptin receptor overlapping transcript	Golgi apparatus	Cellular component	18042720
IDH3A	3419	isocitrate dehydrogenase 3 (NAD+) alpha	mitochondrial matrix	Cellular component	-
GRWD1	83743	glutamate-rich WD repeat containing 1	cytoplasm	Cellular component	-
FGF5	2250	fibroblast growth factor 5	epidermal growth factor receptor signaling pathway	Biological process	-
MCU	90550	mitochondrial calcium uniporter	mitochondrial inner membrane	Cellular component	21685886
TREX2	11219	three prime repair exonuclease 2	magnesium ion binding	Molecular function	11279105
SERPINA5	5104	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5	lipid transport	Biological process	-
SNAI2	6591	snail family zinc finger 2	negative regulation of chondrocyte differentiation	Biological process	19756381
HMGN3	9324	high mobility group nucleosomal binding domain 3	biological_process	Biological process	-
LNX2	222484	ligand of numb-protein X 2	PDZ domain binding	Molecular function	-
GOLGA3	2802	golgin A3	Golgi transport complex	Cellular component	8315394
ZNF20	7568	zinc finger protein 20	nucleus	Cellular component	-
MAEA	10296	macrophage erythroblast attacher	cytoplasm	Cellular component	-
PAWR	5074	PRKC, apoptosis, WT1, regulator	leucine zipper domain binding	Molecular function	14627703
ZNF90	7643	zinc finger protein 90	zinc ion binding	Molecular function	2023909
OSR1	130497	odd-skipped related transciption factor 1	stem cell differentiation	Biological process	-
PTPN6	5777	protein tyrosine phosphatase, non-receptor type 6	abortive mitotic cell cycle	Biological process	-
ACACB	32	acetyl-CoA carboxylase beta	response to organic cyclic compound	Biological process	-
TSPAN32	10077	tetraspanin 32	platelet aggregation	Biological process	-
ADAMTS3	9508	ADAM metallopeptidase with thrombospondin type 1 motif, 3	proteinaceous extracellular matrix	Cellular component	11812023
FIG4	9896	FIG4 phosphoinositide 5-phosphatase	positive regulation of neuron projection development	Biological process	-
IRAK1	3654	interleukin-1 receptor-associated kinase 1	nucleus	Cellular component	-
XRCC6	2547	X-ray repair complementing defective repair in Chinese hamster cells 6	nucleoplasm	Cellular component	-
HIST1H2BF	8343	histone cluster 1, H2bf	extracellular exosome	Cellular component	20458337
HIST2H2AA3	8337	histone cluster 2, H2aa3	nucleosome	Cellular component	-
PPP3CB	5532	protein phosphatase 3, catalytic subunit, beta isozyme	positive regulation of transcription, DNA-templated	Biological process	8978785
PRKCI	5584	protein kinase C, iota	establishment of apical/basal cell polarity	Biological process	-
MRPL46	26589	mitochondrial ribosomal protein L46	hydrolase activity	Molecular function	-
TONSL	4796	tonsoku-like, DNA repair protein	DNA replication factor A complex	Cellular component	21055983
HIST1H4G	8369	histone cluster 1, H4g	nucleus	Cellular component	21630459
GJD2	57369	gap junction protein, delta 2, 36kDa	plasma membrane	Cellular component	-
MED12	9968	mediator complex subunit 12	protein C-terminus binding	Molecular function	17000779
GCA	25801	grancalcin, EF-hand calcium binding protein	calcium ion binding	Molecular function	11717497
SULF1	23213	sulfatase 1	negative regulation of fibroblast growth factor receptor signaling pathway	Biological process	-
TBX5	6910	T-box 5	positive regulation of transcription from RNA polymerase II promoter	Biological process	11431700
IFNL1	282618	interferon, lambda 1	negative regulation of interleukin-13 production	Biological process	19346497
NUP133	55746	nucleoporin 133kDa	viral life cycle	Biological process	-
NDC80	10403	NDC80 kinetochore complex component	attachment of mitotic spindle microtubules to kinetochore	Biological process	-
SYT9	143425	synaptotagmin IX	syntaxin binding	Molecular function	-
SHH	6469	sonic hedgehog	peptidase activity	Molecular function	-
CHCHD4	131474	coiled-coil-helix-coiled-coil-helix domain containing 4	mitochondrial intermembrane space	Cellular component	16185709
FSCN1	6624	fascin actin-bundling protein 1	drug binding	Molecular function	20393565
CYP1B1	1545	cytochrome P450, family 1, subfamily B, polypeptide 1	xenobiotic metabolic process	Biological process	-
HGF	3082	hepatocyte growth factor (hepapoietin A; scatter factor)	positive regulation of peptidyl-tyrosine phosphorylation	Biological process	21245381
PLD6	201164	phospholipase D family, member 6	phosphatidylglycerol biosynthetic process	Biological process	-
GIT1	28964	G protein-coupled receptor kinase interacting ArfGAP 1	ephrin receptor signaling pathway	Biological process	-
AMOT	154796	angiomotin	positive regulation of blood vessel endothelial cell migration	Biological process	16043488
TRMT1	55621	tRNA methyltransferase 1 homolog (S. cerevisiae)	tRNA N2-guanine methylation	Biological process	-
CHEK2	11200	checkpoint kinase 2	ATP binding	Molecular function	-
KPNA1	3836	karyopherin alpha 1 (importin alpha 5)	regulation of DNA recombination	Biological process	8052633
PAPOLB	56903	poly(A) polymerase beta (testis specific)	polynucleotide adenylyltransferase activity	Molecular function	-
TGFB1	7040	transforming growth factor, beta 1	platelet degranulation	Biological process	-
ADM	133	adrenomedullin	cell-cell signaling	Biological process	8074714
MYOCD	93649	myocardin	positive regulation of cardiac vascular smooth muscle cell differentiation	Biological process	-
CNGA4	1262	cyclic nucleotide gated channel alpha 4	organelle organization	Biological process	-
NPFFR2	10886	neuropeptide FF receptor 2	G-protein coupled receptor signaling pathway	Biological process	10079187
HDAC1	3065	histone deacetylase 1	repressing transcription factor binding	Molecular function	16731528
ABL1	25	ABL proto-oncogene 1, non-receptor tyrosine kinase	axon guidance	Biological process	-
EXOSC1	51013	exosome component 1	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	Biological process	-
IQGAP1	8826	IQ motif containing GTPase activating protein 1	microtubule cytoskeleton	Cellular component	-
KCNJ11	3767	potassium channel, inwardly rectifying subfamily J, member 11	protein C-terminus binding	Molecular function	-
BRD9	65980	bromodomain containing 9	regulation of transcription, DNA-templated	Biological process	-
KCNJ12	3768	potassium channel, inwardly rectifying subfamily J, member 12	potassium ion transport	Biological process	20921230
PSMC4	5704	proteasome (prosome, macropain) 26S subunit, ATPase, 4	protein polyubiquitination	Biological process	-
PIK3R1	5295	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
CCDC155	147872	coiled-coil domain containing 155	identical protein binding	Molecular function	-
PNMA6B	728513	paraneoplastic Ma antigen family member 6B (pseudogene)	protein binding	Molecular function	25416956
TUBA3D	113457	tubulin, alpha 3d	microtubule-based process	Biological process	-
LRRC49	54839	leucine rich repeat containing 49	microtubule	Cellular component	-
HSD17B2	3294	hydroxysteroid (17-beta) dehydrogenase 2	testosterone dehydrogenase (NAD+) activity	Molecular function	8099587
ITGA4	3676	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	T cell migration	Biological process	-
RAP2C	57826	RAP2C, member of RAS oncogene family	bicellular tight junction	Cellular component	23885123
NPR3	4883	natriuretic peptide receptor 3	peptide hormone binding	Molecular function	-
OR14A2	388761	olfactory receptor, family 14, subfamily A, member 2	olfactory receptor activity	Molecular function	-
PAEP	5047	progestagen-associated endometrial protein	multicellular organismal development	Biological process	3194393
CASS4	57091	Cas scaffolding protein family member 4	signal transduction by protein phosphorylation	Biological process	-
NXF1	10482	nuclear RNA export factor 1	mRNA export from nucleus	Biological process	-
RBM23	55147	RNA binding motif protein 23	protein binding	Molecular function	22365833
NLRP6	171389	NLR family, pyrin domain containing 6	G-protein coupled receptor signaling pathway	Biological process	-
NGF	4803	nerve growth factor (beta polypeptide)	phosphatidylinositol-mediated signaling	Biological process	-
EPN2	22905	epsin 2	embryonic organ development	Biological process	-
NCKAP1	10787	NCK-associated protein 1	embryonic body morphogenesis	Biological process	-
ADAR	103	adenosine deaminase, RNA-specific	somatic diversification of immune receptors via somatic mutation	Biological process	-
GLUL	2752	glutamate-ammonia ligase	glutamate-ammonia ligase activity	Molecular function	-
TIRAP	114609	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	phosphatidylinositol-4,5-bisphosphate binding	Molecular function	-
NBL1	4681	neuroblastoma 1, DAN family BMP antagonist	protein binding	Molecular function	25416956
CORT	1325	cortistatin	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway	Biological process	9125122
CXCL12	6387	chemokine (C-X-C motif) ligand 12	blood circulation	Biological process	10772939
KCNG3	170850	potassium channel, voltage gated modifier subfamily G, member 3	protein homooligomerization	Biological process	-
SHANK2	22941	SH3 and multiple ankyrin repeat domains 2	neuronal cell body	Cellular component	-
PSMB10	5699	proteasome (prosome, macropain) subunit, beta type, 10	gene expression	Biological process	-
TET3	200424	tet methylcytosine dioxygenase 3	regulation of gene expression, epigenetic	Biological process	-
CDKL2	8999	cyclin-dependent kinase-like 2 (CDC2-related kinase)	cyclin-dependent protein serine/threonine kinase activity	Molecular function	-
NDUFAF1	51103	NADH dehydrogenase (ubiquinone) complex I, assembly factor 1	protein binding	Molecular function	17344420
MCM3	4172	minichromosome maintenance complex component 3	membrane	Cellular component	19946888
ZWILCH	55055	zwilch kinetochore protein	small GTPase mediated signal transduction	Biological process	-
FAM20B	9917	family with sequence similarity 20, member B	nucleoplasm	Cellular component	-
ADK	132	adenosine kinase	phosphotransferase activity, alcohol group as acceptor	Molecular function	-
TRHDE	29953	thyrotropin-releasing hormone degrading enzyme	signal transduction	Biological process	10491199
SLC26A2	1836	solute carrier family 26 (anion exchanger), member 2	membrane	Cellular component	8528239
C3AR1	719	complement component 3a receptor 1	G-protein coupled receptor signaling pathway	Biological process	-
ITGB1	3688	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	cytoplasm	Cellular component	16803572
AHRR	57491	aryl-hydrocarbon receptor repressor	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
DYRK3	8444	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3	magnesium ion binding	Molecular function	10779429
MYCBP2	23077	MYC binding protein 2, E3 ubiquitin protein ligase	microtubule cytoskeleton	Cellular component	-
EFNA1	1942	ephrin-A1	regulation of cell adhesion mediated by integrin	Biological process	10655584
SOX11	6664	SRY (sex determining region Y)-box 11	neuroepithelial cell differentiation	Biological process	-
DHCR7	1717	7-dehydrocholesterol reductase	nuclear outer membrane	Cellular component	9878250
RPTOR	57521	regulatory associated protein of MTOR, complex 1	protein kinase binding	Molecular function	18439900
BSND	7809	barttin CLCNK-type chloride channel accessory beta subunit	transmembrane transport	Biological process	-
TXLNG	55787	taxilin gamma	regulation of cell cycle process	Biological process	18068885
CRELD1	78987	cysteine-rich with EGF-like domains 1	cardiac septum development	Biological process	18076106
ANKRD2	26287	ankyrin repeat domain 2 (stretch responsive muscle)	skeletal muscle cell differentiation	Biological process	-
SMAD1	4086	SMAD family member 1	gamete generation	Biological process	-
TXNDC11	51061	thioredoxin domain containing 11	protein disulfide isomerase activity	Molecular function	-
TMEM38B	55151	transmembrane protein 38B	sarcoplasmic reticulum membrane	Cellular component	19095005
PTGES2	80142	prostaglandin E synthase 2	glutathione binding	Molecular function	-
ZNF737	100129842	zinc finger protein 737	regulation of transcription, DNA-templated	Biological process	-
ENTPD3	956	ectonucleoside triphosphate diphosphohydrolase 3	ATP binding	Molecular function	-
RAB27A	5873	RAB27A, member RAS oncogene family	cellular protein metabolic process	Biological process	-
TUBA3D	113457	tubulin, alpha 3d	nucleus	Cellular component	21630459
SRR	63826	serine racemase	PDZ domain binding	Molecular function	16314870
PPP6R2	9701	protein phosphatase 6, regulatory subunit 2	intracellular membrane-bounded organelle	Cellular component	-
KIAA1324	57535	KIAA1324	extracellular exosome	Cellular component	19199708
RALGAPA2	57186	Ral GTPase activating protein, alpha subunit 2 (catalytic)	protein heterodimerization activity	Molecular function	-
THNSL1	79896	threonine synthase-like 1 (S. cerevisiae)	cytoplasm	Cellular component	-
NOS1AP	9722	nitric oxide synthase 1 (neuronal) adaptor protein	perinuclear region of cytoplasm	Cellular component	18337493
HPRT1	3251	hypoxanthine phosphoribosyltransferase 1	dendrite morphogenesis	Biological process	-
HNMT	3176	histamine N-methyltransferase	neuron projection	Cellular component	-
G6PC	2538	glucose-6-phosphatase, catalytic subunit	gluconeogenesis	Biological process	8211187
SIN3B	23309	SIN3 transcription regulator family member B	chromatin binding	Molecular function	-
WNT10A	80326	wingless-type MMTV integration site family, member 10A	Wnt signaling pathway	Biological process	-
POMC	5443	proopiomelanocortin	generation of precursor metabolites and energy	Biological process	9620771
TRIM27	5987	tripartite motif containing 27	transcription, DNA-templated	Biological process	-
NID1	4811	nidogen 1	collagen binding	Molecular function	22952693
OR9G4	283189	olfactory receptor, family 9, subfamily G, member 4	odorant binding	Molecular function	-
ZNF670	93474	zinc finger protein 670	metal ion binding	Molecular function	-
SETD8	387893	SET domain containing (lysine methyltransferase) 8	mitotic nuclear division	Biological process	-
SUV39H1	6839	suppressor of variegation 3-9 homolog 1 (Drosophila)	histone H3-K9 trimethylation	Biological process	-
VPS37A	137492	vacuolar protein sorting 37 homolog A (S. cerevisiae)	protein transport	Biological process	-
OR4F17	81099	olfactory receptor, family 4, subfamily F, member 17	transmembrane signaling receptor activity	Molecular function	-
TRPT1	83707	tRNA phosphotransferase 1	tRNA splicing, via endonucleolytic cleavage and ligation	Biological process	-
ILK	3611	integrin-linked kinase	nerve development	Biological process	-
CASP8	841	caspase 8, apoptosis-related cysteine peptidase	protein heterodimerization activity	Molecular function	-
DPH1	1801	diphthamide biosynthesis 1	post-translational protein modification	Biological process	-
MAPK12	6300	mitogen-activated protein kinase 12	MAP kinase activity	Molecular function	-
INHBA	3624	inhibin, beta A	cell differentiation	Biological process	12456957
USP9Y	8287	ubiquitin specific peptidase 9, Y-linked	ubiquitin-specific protease activity	Molecular function	9384609
HLA-DRB3	3125	major histocompatibility complex, class II, DR beta 3	T cell costimulation	Biological process	-
BCKDHB	594	branched chain keto acid dehydrogenase E1, beta polypeptide	oxidation-reduction process	Biological process	-
EZR	7430	ezrin	endosome	Cellular component	21148287
TULP1	7287	tubby like protein 1	protein binding	Molecular function	17474147
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation	Biological process	-
CCDC101	112869	coiled-coil domain containing 101	histone H3 acetylation	Biological process	18838386
SLC7A3	84889	solute carrier family 7 (cationic amino acid transporter, y+ system), member 3	antiporter activity	Molecular function	-
PHLDA1	22822	pleckstrin homology-like domain, family A, member 1	FasL biosynthetic process	Biological process	-
PSEN1	5663	presenilin 1	neuron migration	Biological process	-
SCARB1	949	scavenger receptor class B, member 1	transporter activity	Molecular function	9211901
NFKBIA	4792	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	protein import into nucleus, translocation	Biological process	-
EXPH5	23086	exophilin 5	Rab GTPase binding	Molecular function	16880209
PROX1	5629	prospero homeobox 1	atrial cardiac muscle tissue morphogenesis	Biological process	-
UBE2N	7334	ubiquitin-conjugating enzyme E2N	toll-like receptor 2 signaling pathway	Biological process	-
GFRA1	2674	GDNF family receptor alpha 1	receptor binding	Molecular function	9545641
CEP55	55165	centrosomal protein 55kDa	protein binding	Molecular function	16189514
SDC2	6383	syndecan 2	synapse	Cellular component	-
PTH	5741	parathyroid hormone	response to ethanol	Biological process	-
CHRNG	1146	cholinergic receptor, nicotinic, gamma (muscle)	plasma membrane	Cellular component	-
LEPR	3953	leptin receptor	extracellular region	Cellular component	-
KLHL22	84861	kelch-like family member 22	centrosome	Cellular component	23455478
WNT9B	7484	wingless-type MMTV integration site family, member 9B	frizzled binding	Molecular function	-
DDX54	79039	DEAD (Asp-Glu-Ala-Asp) box polypeptide 54	transcription, DNA-templated	Biological process	-
REXO1L1P	254958	REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 1, pseudogene	exonuclease activity	Molecular function	-
RPL23A	6147	ribosomal protein L23a	extracellular exosome	Cellular component	20458337
F2RL1	2150	coagulation factor II (thrombin) receptor-like 1	positive regulation of toll-like receptor 3 signaling pathway	Biological process	19865078
PPP1R9B	84687	protein phosphatase 1, regulatory subunit 9B	filopodium assembly	Biological process	19151759
HM13	81502	histocompatibility (minor) 13	plasma membrane	Cellular component	-
BSN	8927	bassoon presynaptic cytomatrix protein	presynaptic active zone	Cellular component	-
PM20D2	135293	peptidase M20 domain containing 2	extracellular exosome	Cellular component	23376485
SNRPD1	6632	small nuclear ribonucleoprotein D1 polypeptide 16kDa	activation of mitophagy in response to mitochondrial depolarization	Biological process	22020285
LMNB1	4001	lamin B1	nuclear envelope	Cellular component	-
NTRK1	4914	neurotrophic tyrosine kinase, receptor, type 1	learning or memory	Biological process	-
FKBP5	2289	FK506 binding protein 5	protein folding	Biological process	9001212
PRKCI	5584	protein kinase C, iota	protein binding	Molecular function	11257119
TAC1	6863	tachykinin, precursor 1	negative regulation of heart rate	Biological process	-
LIG3	3980	ligase III, DNA, ATP-dependent	lagging strand elongation	Biological process	-
SAA1	6288	serum amyloid A1	extracellular region	Cellular component	-
HSPA4L	22824	heat shock 70kDa protein 4-like	protein folding	Biological process	-
LCK	3932	LCK proto-oncogene, Src family tyrosine kinase	B cell receptor signaling pathway	Biological process	-
SPTB	6710	spectrin, beta, erythrocytic	cytoplasm	Cellular component	-
ANO1	55107	anoctamin 1, calcium activated chloride channel	cytoplasm	Cellular component	-
UROS	7390	uroporphyrinogen III synthase	heme biosynthetic process	Biological process	-
ZNF524	147807	zinc finger protein 524	sequence-specific DNA binding RNA polymerase II transcription factor activity	Molecular function	-
EPHB1	2047	EPH receptor B1	plasma membrane	Cellular component	-
PLCD3	113026	phospholipase C, delta 3	cytosol	Cellular component	-
DLD	1738	dihydrolipoamide dehydrogenase	mitochondrial electron transport, NADH to ubiquinone	Biological process	-
SFI1	9814	Sfi1 homolog, spindle assembly associated (yeast)	negative regulation of phosphatase activity	Biological process	19389623
CCL16	6360	chemokine (C-C motif) ligand 16	positive chemotaxis	Biological process	15001559
SKIL	6498	SKI-like proto-oncogene	gene expression	Biological process	-
NDST3	9348	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3	heparan sulfate proteoglycan biosynthetic process	Biological process	-
ZNF175	7728	zinc finger protein 175	metal ion binding	Molecular function	-
MAPRE1	22919	microtubule-associated protein, RP/EB family, member 1	negative regulation of microtubule polymerization	Biological process	11943150
CRELD1	78987	cysteine-rich with EGF-like domains 1	integral component of membrane	Cellular component	-
ACSL6	23305	acyl-CoA synthetase long-chain family member 6	positive regulation of plasma membrane long-chain fatty acid transport	Biological process	-
CACNA1A	773	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	synaptic transmission, glutamatergic	Biological process	-
FGF10	2255	fibroblast growth factor 10	spleen development	Biological process	-
SLC9A6	10479	solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6	sodium ion transmembrane transport	Biological process	9507001
SGMS1	259230	sphingomyelin synthase 1	cell growth	Biological process	14976195
PGLYRP3	114771	peptidoglycan recognition protein 3	intracellular	Cellular component	11461926
HGSNAT	138050	heparan-alpha-glucosaminide N-acetyltransferase	carbohydrate metabolic process	Biological process	-
ITGB1	3688	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	small GTPase mediated signal transduction	Biological process	-
ARF4	378	ADP-ribosylation factor 4	epidermal growth factor receptor signaling pathway	Biological process	-
ACSM3	6296	acyl-CoA synthetase medium-chain family member 3	butyrate-CoA ligase activity	Molecular function	-
UGT1A4	54657	UDP glucuronosyltransferase 1 family, polypeptide A4	small molecule metabolic process	Biological process	-
UBR2	23304	ubiquitin protein ligase E3 component n-recognin 2	ubiquitin-dependent protein catabolic process via the N-end rule pathway	Biological process	-
SNAPC4	6621	small nuclear RNA activating complex, polypeptide 4, 190kDa	snRNA transcription	Biological process	9418884
PSMB1	5689	proteasome (prosome, macropain) subunit, beta type, 1	threonine-type endopeptidase activity	Molecular function	-
F11R	50848	F11 receptor	protein binding	Molecular function	16189514
MC1R	4157	melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)	protein binding	Molecular function	19329486
AKAP6	9472	A kinase (PRKA) anchor protein 6	protein anchor	Molecular function	10413680
GTF2H1	2965	general transcription factor IIH, polypeptide 1, 62kDa	protein kinase activity	Molecular function	9852112
TACC2	10579	transforming, acidic coiled-coil containing protein 2	interkinetic nuclear migration	Biological process	-
BGLAP	632	bone gamma-carboxyglutamate (gla) protein	osteoblast development	Biological process	-
SLC39A2	29986	solute carrier family 39 (zinc transporter), member 2	cytoplasmic membrane-bounded vesicle	Cellular component	14612438
GALNT14	79623	polypeptide N-acetylgalactosaminyltransferase 14	carbohydrate binding	Molecular function	-
PARK2	5071	parkin RBR E3 ubiquitin protein ligase	positive regulation of transcription from RNA polymerase II promoter	Biological process	23453807
CYP11A1	1583	cytochrome P450, family 11, subfamily A, polypeptide 1	maternal process involved in female pregnancy	Biological process	-
PRAC2	360205	prostate cancer susceptibility candidate 2	nucleus	Cellular component	-
LTF	4057	lactotransferrin	positive regulation of NF-kappaB transcription factor activity	Biological process	20345905
GCC2	9648	GRIP and coiled-coil domain containing 2	protein localization to Golgi apparatus	Biological process	16885419
IRAK1	3654	interleukin-1 receptor-associated kinase 1	interleukin-1-mediated signaling pathway	Biological process	10383454
LIG4	3981	ligase IV, DNA, ATP-dependent	neuron apoptotic process	Biological process	-
TRIM68	55128	tripartite motif containing 68	cytoplasm	Cellular component	-
PTPRU	10076	protein tyrosine phosphatase, receptor type, U	transmembrane receptor protein tyrosine phosphatase signaling pathway	Biological process	8700514
TIMELESS	8914	timeless circadian clock	nucleus	Cellular component	-
RDH5	5959	retinol dehydrogenase 5 (11-cis/9-cis)	retinol metabolic process	Biological process	-
GPC1	2817	glypican 1	plasma membrane	Cellular component	-
OR5F1	338674	olfactory receptor, family 5, subfamily F, member 1	detection of chemical stimulus involved in sensory perception of smell	Biological process	9787077
PRKAA2	5563	protein kinase, AMP-activated, alpha 2 catalytic subunit	cytosol	Cellular component	-
PAOX	196743	polyamine oxidase (exo-N4-amino)	polyamine catabolic process	Biological process	12477380
DOCK4	9732	dedicator of cytokinesis 4	cytosol	Cellular component	20679435
NUDT3	11165	nudix (nucleoside diphosphate linked moiety X)-type motif 3	cell-cell signaling	Biological process	10419486
GDNF	2668	glial cell derived neurotrophic factor	protein homodimerization activity	Molecular function	8493557
RAB23	51715	RAB23, member RAS oncogene family	autophagosome	Cellular component	22452336
FZD8	8325	frizzled class receptor 8	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
GPR161	23432	G protein-coupled receptor 161	positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway	Biological process	-
HLA-E	3133	major histocompatibility complex, class I, E	protection from natural killer cell mediated cytotoxicity	Biological process	25631937
VWA1	64856	von Willebrand factor A domain containing 1	extracellular matrix organization	Biological process	-
GPC2	221914	glypican 2	phototransduction, visible light	Biological process	-
NCF1C	654817	neutrophil cytosolic factor 1C pseudogene	phosphatidylinositol binding	Molecular function	-
LIF	3976	leukemia inhibitory factor	positive regulation of MAPK cascade	Biological process	7508917
OR7A17	26333	olfactory receptor, family 7, subfamily A, member 17	integral component of membrane	Cellular component	-
NKX3-1	4824	NK3 homeobox 1	negative regulation of epithelial cell proliferation involved in prostate gland development	Biological process	-
OR4C3	256144	olfactory receptor, family 4, subfamily C, member 3	G-protein coupled receptor activity	Molecular function	-
ADAM17	6868	ADAM metallopeptidase domain 17	cell surface	Cellular component	18383040
IL13RA2	3598	interleukin 13 receptor, alpha 2	cytokine-mediated signaling pathway	Biological process	9725226
CP	1356	ceruloplasmin (ferroxidase)	copper ion binding	Molecular function	-
EIF2AK2	5610	eukaryotic translation initiation factor 2-alpha kinase 2	positive regulation of stress-activated MAPK cascade	Biological process	-
OR5D14	219436	olfactory receptor, family 5, subfamily D, member 14	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
CHRNA3	1136	cholinergic receptor, nicotinic, alpha 3 (neuronal)	synaptic transmission involved in micturition	Biological process	11450844
SERPINH1	871	serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)	extracellular matrix organization	Biological process	-
PAQR4	124222	progestin and adipoQ receptor family member IV	receptor activity	Molecular function	-
PACSIN2	11252	protein kinase C and casein kinase substrate in neurons 2	actin cytoskeleton organization	Biological process	-
FOXF1	2294	forkhead box F1	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity	Molecular function	-
ACTR6	64431	ARP6 actin-related protein 6 homolog (yeast)	cytoplasm	Cellular component	-
MAPK10	5602	mitogen-activated protein kinase 10	toll-like receptor 2 signaling pathway	Biological process	-
EDNRA	1909	endothelin receptor type A	positive regulation of cell proliferation	Biological process	-
TMEM204	79652	transmembrane protein 204	integral component of membrane	Cellular component	-
CDC42	998	cell division cycle 42	sprouting angiogenesis	Biological process	-
ATF1	466	activating transcription factor 1	toll-like receptor TLR6:TLR2 signaling pathway	Biological process	-
SIN3A	25942	SIN3 transcription regulator family member A	cellular protein localization	Biological process	-
RAB25	57111	RAB25, member RAS oncogene family	cytoplasmic vesicle	Cellular component	17925226
CTSW	1521	cathepsin W	extracellular space	Cellular component	-
KIF5A	3798	kinesin family member 5A	blood coagulation	Biological process	-
RASSF5	83593	Ras association (RalGDS/AF-6) domain family member 5	positive regulation of protein ubiquitination	Biological process	-
VEGFA	7422	vascular endothelial growth factor A	neuropilin binding	Molecular function	24401374
GUCY1B3	2983	guanylate cyclase 1, soluble, beta 3	GTP binding	Molecular function	-
HFE2	148738	hemochromatosis type 2 (juvenile)	plasma membrane	Cellular component	16075058
SEC11B	157708	SEC11 homolog B, pseudogene (S. cerevisiae)	integral component of membrane	Cellular component	-
DDB2	1643	damage-specific DNA binding protein 2, 48kDa	protein autoubiquitination	Biological process	12732143
ZCRB1	85437	zinc finger CCHC-type and RNA binding motif 1	nucleoplasm	Cellular component	-
ASZ1	136991	ankyrin repeat, SAM and basic leucine zipper domain containing 1	cell differentiation	Biological process	-
ATG7	10533	autophagy related 7	cellular response to nitrogen starvation	Biological process	-
MAP3K7	6885	mitogen-activated protein kinase kinase kinase 7	plasma membrane	Cellular component	-
WIPI2	26100	WD repeat domain, phosphoinositide interacting 2	phosphatidylinositol-3-phosphate binding	Molecular function	20505359
RELA	5970	v-rel avian reticuloendotheliosis viral oncogene homolog A	negative regulation of protein catabolic process	Biological process	-
SP100	6672	SP100 nuclear antigen	kinase binding	Molecular function	14647468
MYOG	4656	myogenin (myogenic factor 4)	skeletal muscle fiber development	Biological process	-
POR	5447	P450 (cytochrome) oxidoreductase	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	Molecular function	-
NFKB1	4790	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	toll-like receptor TLR1:TLR2 signaling pathway	Biological process	-
MORF4L1	10933	mortality factor 4 like 1	histone deacetylation	Biological process	14966270
ANK3	288	ankyrin 3, node of Ranvier (ankyrin G)	maintenance of protein location in plasma membrane	Biological process	17620337
FLT1	2321	fms-related tyrosine kinase 1	transmembrane receptor protein tyrosine kinase signaling pathway	Biological process	2158038
GAD2	2572	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)	protein binding	Molecular function	10671565
ALDOA	226	aldolase A, fructose-bisphosphate	muscle cell cellular homeostasis	Biological process	14615364
MKKS	8195	McKusick-Kaufman syndrome	cytosol	Cellular component	-
MMP9	4318	matrix metallopeptidase 9	positive regulation of keratinocyte migration	Biological process	17704059
SMO	6608	smoothened, frizzled class receptor	osteoblast differentiation	Biological process	-
IL23A	51561	interleukin 23, alpha subunit p19	positive regulation of natural killer cell proliferation	Biological process	19088061
MOAP1	64112	modulator of apoptosis 1	cytosol	Cellular component	19100260
CACNA2D2	9254	calcium channel, voltage-dependent, alpha 2/delta subunit 2	regulation of ion transmembrane transport	Biological process	-
SPHK1	8877	sphingosine kinase 1	sphingolipid metabolic process	Biological process	-
IKBKG	8517	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	MyD88-dependent toll-like receptor signaling pathway	Biological process	-
ZC3H12B	340554	zinc finger CCCH-type containing 12B	endonuclease activity	Molecular function	-
ONECUT3	390874	one cut homeobox 3	RNA polymerase II regulatory region sequence-specific DNA binding	Molecular function	-
LRIG2	9860	leucine-rich repeats and immunoglobulin-like domains 2	regulation of platelet-derived growth factor receptor signaling pathway	Biological process	-
FUZ	80199	fuzzy planar cell polarity protein	regulation of smoothened signaling pathway	Biological process	-
GSG2	83903	germ cell associated 2 (haspin)	protein localization to chromosome, centromeric region	Biological process	20705812
TMED2	10959	transmembrane emp24 domain trafficking protein 2	endoplasmic reticulum membrane	Cellular component	-
CNOT6L	246175	CCR4-NOT transcription complex, subunit 6-like	positive regulation of cell proliferation	Biological process	21233283
ALG10B	144245	ALG10B, alpha-1,2-glucosyltransferase	protein N-linked glycosylation via asparagine	Biological process	-
TH	7054	tyrosine hydroxylase	eye photoreceptor cell development	Biological process	-
MRPS35	60488	mitochondrial ribosomal protein S35	structural constituent of ribosome	Molecular function	-
PLCG1	5335	phospholipase C, gamma 1	positive regulation of epithelial cell migration	Biological process	17229814
ATR	545	ATR serine/threonine kinase	PML body	Cellular component	12814551
FGF10	2255	fibroblast growth factor 10	response to estradiol	Biological process	-
ABHD15	116236	abhydrolase domain containing 15	membrane	Cellular component	19946888
CHD2	1106	chromodomain helicase DNA binding protein 2	regulation of transcription from RNA polymerase II promoter	Biological process	9326634
XPC	7508	xeroderma pigmentosum, complementation group C	plasma membrane	Cellular component	-
PPID	5481	peptidylprolyl isomerase D	peptidyl-prolyl cis-trans isomerase activity	Molecular function	11350175
OR4S2	219431	olfactory receptor, family 4, subfamily S, member 2	detection of chemical stimulus involved in sensory perception	Biological process	-
RASGRP1	10125	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	Golgi apparatus	Cellular component	21968647
DENND6B	414918	DENN/MADD domain containing 6B	positive regulation of GTPase activity	Biological process	-
PLTP	5360	phospholipid transfer protein	positive regulation of cholesterol efflux	Biological process	24369175
PLD1	5337	phospholipase D1, phosphatidylcholine-specific	Golgi apparatus	Cellular component	14718562
IDO1	3620	indoleamine 2,3-dioxygenase 1	cellular nitrogen compound metabolic process	Biological process	-
CREB3L2	64764	cAMP responsive element binding protein 3-like 2	ER to Golgi vesicle-mediated transport	Biological process	-
FRZB	2487	frizzled-related protein	negative regulation of hepatocyte differentiation	Biological process	-
HRC	3270	histidine rich calcium binding protein	regulation of cell communication by electrical coupling involved in cardiac conduction	Biological process	24125847
PRKAA1	5562	protein kinase, AMP-activated, alpha 1 catalytic subunit	positive regulation of autophagy	Biological process	-
PPP3CC	5533	protein phosphatase 3, catalytic subunit, gamma isozyme	protein binding	Molecular function	25416956
PXT1	222659	peroxisomal, testis specific 1	nucleus	Cellular component	-
PTPN6	5777	protein tyrosine phosphatase, non-receptor type 6	cytokine-mediated signaling pathway	Biological process	-
ACCS	84680	1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)	pyridoxal phosphate binding	Molecular function	11470512
TPH1	7166	tryptophan hydroxylase 1	cytosol	Cellular component	-
KRTAP1-1	81851	keratin associated protein 1-1	biological_process	Biological process	-
GRIK2	2898	glutamate receptor, ionotropic, kainate 2	integral component of plasma membrane	Cellular component	7536611
ARF1	375	ADP-ribosylation factor 1	protein transport	Biological process	-
AHR	196	aryl hydrocarbon receptor	enhancer binding	Molecular function	23275542
NEDD4L	23327	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase	negative regulation of sodium ion transmembrane transporter activity	Biological process	15217910
HSPA5	3309	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	endoplasmic reticulum lumen	Cellular component	-
RPL10A	4736	ribosomal protein L10a	gene expression	Biological process	-
PCSK9	255738	proprotein convertase subtilisin/kexin type 9	cholesterol homeostasis	Biological process	17170371
TXNDC2	84203	thioredoxin domain containing 2 (spermatozoa)	cytoplasm	Cellular component	-
GOT2	2806	glutamic-oxaloacetic transaminase 2, mitochondrial	oxaloacetate metabolic process	Biological process	-
TNFRSF1A	7132	tumor necrosis factor receptor superfamily, member 1A	viral process	Biological process	-
JAK2	3717	Janus kinase 2	activation of JAK2 kinase activity	Biological process	-
HSPA2	3306	heat shock 70kDa protein 2	enzyme binding	Molecular function	23921388
SLC26A6	65010	solute carrier family 26 (anion exchanger), member 6	apical plasma membrane	Cellular component	11087667
ADORA2A	135	adenosine A2a receptor	regulation of mitochondrial membrane potential	Biological process	-
BCKDHB	594	branched chain keto acid dehydrogenase E1, beta polypeptide	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity	Molecular function	-
MAPK8	5599	mitogen-activated protein kinase 8	response to stress	Biological process	8137421
POLI	11201	polymerase (DNA directed) iota	error-prone translesion synthesis	Biological process	-
AHNAK	79026	AHNAK nucleoprotein	S100 protein binding	Molecular function	14699089
SCMH1	22955	sex comb on midleg homolog 1 (Drosophila)	post-translational protein modification	Biological process	-
RASGRP1	10125	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	activation of GTPase activity	Biological process	12845332
GLI3	2737	GLI family zinc finger 3	optic nerve morphogenesis	Biological process	-
PSMB6	5694	proteasome (prosome, macropain) subunit, beta type, 6	regulation of apoptotic process	Biological process	-
AURKA	6790	aurora kinase A	regulation of cytokinesis	Biological process	-
SNAI2	6591	snail family zinc finger 2	neural crest cell development	Biological process	12444107
HIST1H3H	8357	histone cluster 1, H3h	membrane	Cellular component	19946888
DNM2	1785	dynamin 2	extracellular exosome	Cellular component	19056867
UTRN	7402	utrophin	filopodium	Cellular component	16803572
PRKACB	5567	protein kinase, cAMP-dependent, catalytic, beta	regulation of insulin secretion	Biological process	-
NEFM	4741	neurofilament, medium polypeptide	microtubule binding	Molecular function	17498690
CRX	1406	cone-rod homeobox	nuclear hormone receptor binding	Molecular function	-
MXD4	10608	MAX dimerization protein 4	protein binding	Molecular function	15469726
FOXE1	2304	forkhead box E1	thyroid hormone generation	Biological process	-
VHL	7428	von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase	positive regulation of transcription, DNA-templated	Biological process	17973242
MLLT3	4300	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3	negative regulation of canonical Wnt signaling pathway	Biological process	19591803
HLA-DQA1	3117	major histocompatibility complex, class II, DQ alpha 1	peptide antigen binding	Molecular function	20356827
SPOCK1	6695	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1	proteinaceous extracellular matrix	Cellular component	-
ATP1A4	480	ATPase, Na+/K+ transporting, alpha 4 polypeptide	sodium ion transmembrane transport	Biological process	7809153
RET	5979	ret proto-oncogene	receptor activity	Molecular function	7824936
ATG2A	23130	autophagy related 2A	autophagosome assembly	Biological process	-
MRPS10	55173	mitochondrial ribosomal protein S10	biological_process	Biological process	-
PPP1CC	5501	protein phosphatase 1, catalytic subunit, gamma isozyme	nucleolus	Cellular component	11739654
PAFAH1B1	5048	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	axon	Cellular component	-
ALOX12B	242	arachidonate 12-lipoxygenase, 12R type	positive regulation of MAPK cascade	Biological process	22441738
TGFA	7039	transforming growth factor, alpha	epidermal growth factor receptor binding	Molecular function	11278323
BACE2	25825	beta-site APP-cleaving enzyme 2	negative regulation of amyloid precursor protein biosynthetic process	Biological process	12801932
TEKT1	83659	tektin 1	nucleus	Cellular component	21630459
HIST2H2AC	8338	histone cluster 2, H2ac	nucleosome	Cellular component	-
PELI3	246330	pellino E3 ubiquitin protein ligase family member 3	protein binding	Molecular function	25814554
ITGA8	8516	integrin, alpha 8	memory	Biological process	-
TBC1D14	57533	TBC1 domain family, member 14	recycling endosome to Golgi transport	Biological process	17562788
ABCA2	20	ATP-binding cassette, sub-family A (ABC1), member 2	ATPase activity, coupled to transmembrane movement of substances	Molecular function	7766993
LBH	81606	limb bud and heart development	regulation of blood coagulation	Biological process	21810271
FGF7	2252	fibroblast growth factor 7	mesenchymal cell proliferation	Biological process	11023837
EXT2	2132	exostosin glycosyltransferase 2	Golgi apparatus	Cellular component	-
P2RX5	5026	purinergic receptor P2X, ligand gated ion channel, 5	ion channel activity	Molecular function	9414125
DAPP1	27071	dual adaptor of phosphotyrosine and 3-phosphoinositides	phospholipid binding	Molecular function	10432293
ACVR1	90	activin A receptor, type I	determination of left/right symmetry	Biological process	-
LIG3	3980	ligase III, DNA, ATP-dependent	protein binding	Molecular function	15744309
WNT8A	7478	wingless-type MMTV integration site family, member 8A	neural crest cell fate commitment	Biological process	-
APOC2	344	apolipoprotein C-II	chylomicron remnant clearance	Biological process	4020294
NTF4	4909	neurotrophin 4	mechanoreceptor differentiation	Biological process	-
PSMC3IP	29893	PSMC3 interacting protein	ligand-dependent nuclear receptor transcription coactivator activity	Molecular function	21963259
ADRB1	153	adrenoceptor beta 1	protein localization to organelle	Biological process	-
NCSTN	23385	nicastrin	ephrin receptor signaling pathway	Biological process	-
SLC25A23	79085	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23	urea homeostasis	Biological process	-
PDGFRB	5159	platelet-derived growth factor receptor, beta polypeptide	metanephric glomerular mesangial cell proliferation involved in metanephros development	Biological process	-
ARHGEF2	9181	Rho/Rac guanine nucleotide exchange factor (GEF) 2	Golgi apparatus	Cellular component	-
C2CD3	26005	C2 calcium-dependent domain containing 3	neural plate axis specification	Biological process	-
EIF3F	8665	eukaryotic translation initiation factor 3, subunit F	eukaryotic translation initiation factor 3 complex	Cellular component	9341143
TCEB1	6921	transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)	regulation of transcription from RNA polymerase II promoter in response to hypoxia	Biological process	-
NGFR	4804	nerve growth factor receptor	positive regulation of axonogenesis	Biological process	-
PREB	10113	prolactin regulatory element binding	ER to Golgi vesicle-mediated transport	Biological process	-
GDPD1	284161	glycerophosphodiester phosphodiesterase domain containing 1	membrane	Cellular component	19946888
PITPNM1	9600	phosphatidylinositol transfer protein, membrane-associated 1	endoplasmic reticulum membrane	Cellular component	-
PTAFR	5724	platelet-activating factor receptor	plasma membrane	Cellular component	-
DNM1	1759	dynamin 1	GTP binding	Molecular function	-
PRKCZ	5590	protein kinase C, zeta	apical plasma membrane	Cellular component	-
KIF1B	23095	kinesin family member 1B	ATP binding	Molecular function	-
RAC1	5879	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	regulation of hydrogen peroxide metabolic process	Biological process	16636067
TGFB1	7040	transforming growth factor, beta 1	response to drug	Biological process	-
PANX2	56666	pannexin 2	protein hexamerization	Biological process	-
CAMK2A	815	calcium/calmodulin-dependent protein kinase II alpha	positive regulation of cardiac muscle cell apoptotic process	Biological process	-
VGF	7425	VGF nerve growth factor inducible	response to insulin	Biological process	-
IL24	11009	interleukin 24	negative regulation of cell proliferation	Biological process	-
BBOX1	8424	butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1	cellular nitrogen compound metabolic process	Biological process	-
JUN	3725	jun proto-oncogene	positive regulation by host of viral transcription	Biological process	2833704
TUB	7275	tubby bipartite transcription factor	retina development in camera-type eye	Biological process	-
ZFP36	7538	ZFP36 ring finger protein	mRNA 3'-UTR AU-rich region binding	Molecular function	25038453
PCSK9	255738	proprotein convertase subtilisin/kexin type 9	receptor inhibitor activity	Molecular function	22848640
TAAR6	319100	trace amine associated receptor 6	G-protein coupled receptor signaling pathway	Biological process	15718104
DVL2	1856	dishevelled segment polarity protein 2	segment specification	Biological process	-
HIST1H4D	8360	histone cluster 1, H4d	DNA replication-independent nucleosome assembly	Biological process	14718166
PRKD1	5587	protein kinase D1	regulation of integrin-mediated signaling pathway	Biological process	21488147
FCER1G	2207	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	immunoglobulin mediated immune response	Biological process	-
ONECUT2	9480	one cut homeobox 2	cilium assembly	Biological process	-
AKR1A1	10327	aldo-keto reductase family 1, member A1 (aldehyde reductase)	L-ascorbic acid biosynthetic process	Biological process	-
ACHE	43	acetylcholinesterase (Yt blood group)	negative regulation of synaptic transmission, cholinergic	Biological process	1517212
APOBEC3H	164668	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H	nucleus	Cellular component	18779051
FOXF1	2294	forkhead box F1	branching involved in open tracheal system development	Biological process	19500772
CDK5	1020	cyclin-dependent kinase 5	negative regulation of axon extension	Biological process	-
RPS6KA2	6196	ribosomal protein S6 kinase, 90kDa, polypeptide 2	axon guidance	Biological process	-
LSM10	84967	LSM10, U7 small nuclear RNA associated	mRNA 3'-end processing	Biological process	-
CLTA	1211	clathrin, light chain A	clathrin heavy chain binding	Molecular function	4066749
CTSB	1508	cathepsin B	proteolysis involved in cellular protein catabolic process	Biological process	22952693
CCK	885	cholecystokinin	regulation of sensory perception of pain	Biological process	-
DUSP28	285193	dual specificity phosphatase 28	protein tyrosine phosphatase activity	Molecular function	-
L1CAM	3897	L1 cell adhesion molecule	homophilic cell adhesion via plasma membrane adhesion molecules	Biological process	-
ACE	1636	angiotensin I converting enzyme	spermatogenesis	Biological process	-
PIH1D3	139212	PIH1 domain containing 3	sperm motility	Biological process	-
MEIS1	4211	Meis homeobox 1	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity	Molecular function	-
ITIH1	3697	inter-alpha-trypsin inhibitor heavy chain 1	negative regulation of endopeptidase activity	Biological process	-
MAP7D1	55700	MAP7 domain containing 1	cytoplasm	Cellular component	-
PCDHA12	56137	protocadherin alpha 12	homophilic cell adhesion via plasma membrane adhesion molecules	Biological process	-
ARG2	384	arginase 2	arginase activity	Molecular function	16128822
HPX	3263	hemopexin	positive regulation of immunoglobulin production	Biological process	-
MUC22	100507679	mucin 22	plasma membrane	Cellular component	-
BBS5	129880	Bardet-Biedl syndrome 5	protein transport	Biological process	-
MCM2	4171	minichromosome maintenance complex component 2	microtubule cytoskeleton	Cellular component	-
KRT17	3872	keratin 17, type I	keratinization	Biological process	-
AOC1	26	amine oxidase, copper containing 1	calcium ion binding	Molecular function	12072962
PPRC1	23082	peroxisome proliferator-activated receptor gamma, coactivator-related 1	transcription factor binding	Molecular function	-
PITX2	5308	paired-like homeodomain 2	RNA polymerase II transcription factor binding	Molecular function	15466416
CPSF4L	642843	cleavage and polyadenylation specific factor 4-like	metal ion binding	Molecular function	-
GTF2H5	404672	general transcription factor IIH, polypeptide 5	cellular response to gamma radiation	Biological process	-
MSX1	4487	msh homeobox 1	positive regulation of BMP signaling pathway	Biological process	-
KMT2C	58508	lysine (K)-specific methyltransferase 2C	DNA binding	Molecular function	-
RTN1	6252	reticulon 1	endomembrane system	Cellular component	-
HDAC2	3066	histone deacetylase 2	chromatin remodeling	Biological process	17827154
TIGIT	201633	T cell immunoreceptor with Ig and ITIM domains	cell surface	Cellular component	19011627
SEBOX	645832	SEBOX homeobox	cellular_component	Cellular component	-
CCR5	1234	chemokine (C-C motif) receptor 5 (gene/pseudogene)	dendritic cell chemotaxis	Biological process	16621978
KRT18	3875	keratin 18, type I	negative regulation of apoptotic process	Biological process	11684708
OXTR	5021	oxytocin receptor	G-protein coupled receptor signaling pathway	Biological process	-
BCAP31	10134	B-cell receptor-associated protein 31	membrane	Cellular component	19946888
ZFYVE19	84936	zinc finger, FYVE domain containing 19	abscission	Biological process	24814515
OR8K3	219473	olfactory receptor, family 8, subfamily K, member 3 (gene/pseudogene)	sensory perception of smell	Biological process	-
TPR	7175	translocated promoter region, nuclear basket protein	nuclear inclusion body	Cellular component	11514627
CEP83	51134	centrosomal protein 83kDa	molecular_function	Molecular function	-
OLIG2	10215	oligodendrocyte lineage transcription factor 2	neuron fate commitment	Biological process	-
TPT1	7178	tumor protein, translationally-controlled 1	poly(A) RNA binding	Molecular function	22658674
ELOVL6	79071	ELOVL fatty acid elongase 6	long-chain fatty acid biosynthetic process	Biological process	20937905
RPS4X	6191	ribosomal protein S4, X-linked	translational elongation	Biological process	-
LIMK1	3984	LIM domain kinase 1	protein binding	Molecular function	10559936
ATXN1	6310	ataxin 1	negative regulation of phosphorylation	Biological process	-
EVI5L	115704	ecotropic viral integration site 5-like	GTPase activator activity	Molecular function	17646400
CLIC3	9022	chloride intracellular channel 3	signal transduction	Biological process	9880541
DPP6	1804	dipeptidyl-peptidase 6	plasma membrane	Cellular component	-
SOX4	6659	SRY (sex determining region Y)-box 4	cytoplasm	Cellular component	17875931
KLK7	5650	kallikrein-related peptidase 7	proteolysis	Biological process	-
OR2T3	343173	olfactory receptor, family 2, subfamily T, member 3	G-protein coupled receptor activity	Molecular function	-
RPS6KA2	6196	ribosomal protein S6 kinase, 90kDa, polypeptide 2	toll-like receptor TLR6:TLR2 signaling pathway	Biological process	-
MITF	4286	microphthalmia-associated transcription factor	positive regulation of transcription from RNA polymerase II promoter	Biological process	14737107
OR4D10	390197	olfactory receptor, family 4, subfamily D, member 10	plasma membrane	Cellular component	-
ALG2	85365	ALG2, alpha-1,3/1,6-mannosyltransferase	protein glycosylation in endoplasmic reticulum	Biological process	12684507
MAP2K6	5608	mitogen-activated protein kinase kinase 6	protein serine/threonine kinase activity	Molecular function	-
AMY1A	276	amylase, alpha 1A (salivary)	carbohydrate metabolic process	Biological process	-
PRAMEF16	654348	PRAME family member 16	negative regulation of transcription, DNA-templated	Biological process	-
COIL	8161	coilin	membrane	Cellular component	19946888
HRH3	11255	histamine receptor H3	learning	Biological process	-
CDKN2B	1030	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	transforming growth factor beta receptor signaling pathway	Biological process	-
NOP10	55505	NOP10 ribonucleoprotein	pseudouridine synthesis	Biological process	9843512
SBF2	81846	SET binding factor 2	membrane	Cellular component	15998640
C9orf72	203228	chromosome 9 open reading frame 72	nucleus	Cellular component	24549040
LRRK2	120892	leucine-rich repeat kinase 2	extracellular space	Cellular component	22664934
OGFOD1	55239	2-oxoglutarate and iron-dependent oxygenase domain containing 1	peptidyl-proline dioxygenase activity	Molecular function	24550447
OR6S1	341799	olfactory receptor, family 6, subfamily S, member 1	G-protein coupled receptor activity	Molecular function	-
RARA	5914	retinoic acid receptor, alpha	ureteric bud development	Biological process	-
ZAP70	7535	zeta-chain (TCR) associated protein kinase 70kDa	T cell activation	Biological process	20135127
LRRK2	120892	leucine-rich repeat kinase 2	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
CD74	972	CD74 molecule, major histocompatibility complex, class II invariant chain	positive regulation of cytokine-mediated signaling pathway	Biological process	12782713
RNF13	11342	ring finger protein 13	late endosome membrane	Cellular component	-
FAM32A	26017	family with sequence similarity 32, member A	mitochondrion	Cellular component	-
MEIS3P1	4213	Meis homeobox 3 pseudogene 1	regulation of transcription, DNA-templated	Biological process	-
MAGI2	9863	membrane associated guanylate kinase, WW and PDZ domain containing 2	glomerular visceral epithelial cell development	Biological process	-
CDK16	5127	cyclin-dependent kinase 16	spermatogenesis	Biological process	-
FASN	2194	fatty acid synthase	energy reserve metabolic process	Biological process	-
ACTL6A	86	actin-like 6A	npBAF complex	Cellular component	-
UCN	7349	urocortin	positive regulation of DNA replication	Biological process	-
TFAP2B	7021	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	RNA polymerase II core promoter sequence-specific DNA binding	Molecular function	7555706
KCNJ11	3767	potassium channel, inwardly rectifying subfamily J, member 11	ankyrin binding	Molecular function	20610380
MALSU1	115416	mitochondrial assembly of ribosomal large subunit 1	protein binding	Molecular function	25416956
CSK	1445	c-src tyrosine kinase	oligodendrocyte differentiation	Biological process	-
EREG	2069	epiregulin	positive regulation of DNA replication	Biological process	-
PLXDC1	57125	plexin domain containing 1	dendrite	Cellular component	-
PTPRCAP	5790	protein tyrosine phosphatase, receptor type, C-associated protein	defense response	Biological process	7961877
WNK3	65267	WNK lysine deficient protein kinase 3	adherens junction	Cellular component	-
DAPK3	1613	death-associated protein kinase 3	regulation of cell shape	Biological process	-
EIF3J	8669	eukaryotic translation initiation factor 3, subunit J	eukaryotic 48S preinitiation complex	Cellular component	-
UPF1	5976	UPF1 regulator of nonsense transcripts homolog (yeast)	cytoplasmic mRNA processing body	Cellular component	-
WASH1	100287171	WAS protein family homolog 1	centriole	Cellular component	-
CCDC36	339834	coiled-coil domain containing 36	protein binding	Molecular function	21516116
DTX1	1840	deltex 1, E3 ubiquitin ligase	glial cell differentiation	Biological process	-
ACSF3	197322	acyl-CoA synthetase family member 3	fatty acid biosynthetic process	Biological process	21846720
HOMER2	9455	homer scaffolding protein 2	protein domain specific binding	Molecular function	-
BMP4	652	bone morphogenetic protein 4	positive regulation of DNA-dependent DNA replication	Biological process	15516325
PPFIA2	8499	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2	cell-matrix adhesion	Biological process	9624153
OR8U9	504190	olfactory receptor, family 8, subfamily U, member 9	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
PROX1	5629	prospero homeobox 1	lymphangiogenesis	Biological process	12412020
MACROD2	140733	MACRO domain containing 2	deacetylase activity	Molecular function	21257746
NLGN1	22871	neuroligin 1	neuronal postsynaptic density	Cellular component	15797875
AP4B1	10717	adaptor-related protein complex 4, beta 1 subunit	protein transporter activity	Molecular function	-
GIPC1	10755	GIPC PDZ domain containing family, member 1	brush border	Cellular component	-
NSRP1	84081	nuclear speckle splicing regulatory protein 1	RNA splicing	Biological process	-
SBF2	81846	SET binding factor 2	myelination	Biological process	15998640
NEUROG1	4762	neurogenin 1	DNA binding	Molecular function	-
FNTA	2339	farnesyltransferase, CAAX box, alpha	regulation of receptor activity	Biological process	-
NEK6	10783	NIMA-related kinase 6	protein binding	Molecular function	16476580
ANKFY1	51479	ankyrin repeat and FYVE domain containing 1	endosome localization	Biological process	24102721
GABBR2	9568	gamma-aminobutyric acid (GABA) B receptor, 2	cytoplasm	Cellular component	-
FAF1	11124	Fas (TNFRSF6) associated factor 1	VCP-NPL4-UFD1 AAA ATPase complex	Cellular component	18775313
TAS2R8	50836	taste receptor, type 2, member 8	detection of chemical stimulus involved in sensory perception of bitter taste	Biological process	20022913
INSM2	84684	insulinoma-associated 2	regulation of transcription, DNA-templated	Biological process	-
AP1M2	10053	adaptor-related protein complex 1, mu 2 subunit	cytosol	Cellular component	-
HOMER1	9456	homer scaffolding protein 1	Z disc	Cellular component	-
YBEY	54059	ybeY metallopeptidase (putative)	proteolysis	Biological process	-
DENND1B	163486	DENN/MADD domain containing 1B	Rab guanyl-nucleotide exchange factor activity	Molecular function	20937701
ESCO2	157570	establishment of sister chromatid cohesion N-acetyltransferase 2	XY body	Cellular component	-
ARF5	381	ADP-ribosylation factor 5	protein transport	Biological process	-
NSMCE1	197370	non-SMC element 1 homolog (S. cerevisiae)	nucleoplasm	Cellular component	-
FOS	2353	FBJ murine osteosarcoma viral oncogene homolog	membrane	Cellular component	-
SCG5	6447	secretogranin V	protein binding	Molecular function	25416956
LOX	4015	lysyl oxidase	collagen fibril organization	Biological process	-
IL6R	3570	interleukin 6 receptor	protein binding	Molecular function	11238858
RFC2	5982	replication factor C (activator 1) 2, 40kDa	DNA damage response, detection of DNA damage	Biological process	-
PDCD6	10016	programmed cell death 6	endoplasmic reticulum membrane	Cellular component	-
TK1	7083	thymidine kinase 1, soluble	cytosol	Cellular component	-
P2RY1	5028	purinergic receptor P2Y, G-protein coupled, 1	positive regulation of protein phosphorylation	Biological process	-
RFC1	5981	replication factor C (activator 1) 1, 145kDa	telomere maintenance via recombination	Biological process	-
FGF8	2253	fibroblast growth factor 8 (androgen-induced)	canonical Wnt signaling pathway	Biological process	-
SRSF1	6426	serine/arginine-rich splicing factor 1	RS domain binding	Molecular function	-
SREBF1	6720	sterol regulatory element binding transcription factor 1	regulation of protein targeting to mitochondrion	Biological process	24912190
ENDOG	2021	endonuclease G	positive regulation of apoptotic process	Biological process	-
NF1	4763	neurofibromin 1	negative regulation of endothelial cell proliferation	Biological process	16648142
PRIM2	5558	primase, DNA, polypeptide 2 (58kDa)	DNA replication initiation	Biological process	-
CREBBP	1387	CREB binding protein	core promoter proximal region sequence-specific DNA binding	Molecular function	21539536
AMIGO2	347902	adhesion molecule with Ig-like domain 2	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	Biological process	12629050
CHMP4B	128866	charged multivesicular body protein 4B	ESCRT III complex	Cellular component	21975012
TSPAN13	27075	tetraspanin 13	membrane	Cellular component	10719184
QTRTD1	79691	queuine tRNA-ribosyltransferase domain containing 1	mitochondrion	Cellular component	-
DLG1	1739	discs, large homolog 1 (Drosophila)	embryonic skeletal system morphogenesis	Biological process	-
ENC1	8507	ectodermal-neural cortex 1 (with BTB domain)	nuclear chromatin	Cellular component	-
AMOTL1	154810	angiomotin like 1	bicellular tight junction	Cellular component	16019084
NKX2-5	1482	NK2 homeobox 5	regulation of cardiac muscle contraction	Biological process	8900537
BCL2	596	B-cell CLL/lymphoma 2	programmed cell death	Biological process	-
SNRPD2	6633	small nuclear ribonucleoprotein D2 polypeptide 16.5kDa	spliceosomal complex	Cellular component	1701240
MMP1	4312	matrix metallopeptidase 1	calcium ion binding	Molecular function	-
NDUFS1	4719	NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)	reactive oxygen species metabolic process	Biological process	15186778
SOSTDC1	25928	sclerostin domain containing 1	negative regulation of BMP signaling pathway	Biological process	-
MRPL4	51073	mitochondrial ribosomal protein L4	ribosome	Cellular component	-
TSPAN2	10100	tetraspanin 2	brain development	Biological process	-
RPS6KB1	6198	ribosomal protein S6 kinase, 70kDa, polypeptide 1	ATP binding	Molecular function	-
PPIG	9360	peptidylprolyl isomerase G (cyclophilin G)	protein folding	Biological process	-
DHCR24	1718	24-dehydrocholesterol reductase	flavin adenine dinucleotide binding	Molecular function	-
SERGEF	26297	secretion regulating guanine nucleotide exchange factor	nucleus	Cellular component	-
SMAD2	4087	SMAD family member 2	pancreas development	Biological process	-
DSG3	1830	desmoglein 3	extracellular exosome	Cellular component	19056867
IRF3	3661	interferon regulatory factor 3	macrophage apoptotic process	Biological process	16846591
EPHX1	2052	epoxide hydrolase 1, microsomal (xenobiotic)	aromatic compound catabolic process	Biological process	-
ZNF286A	57335	zinc finger protein 286A	protein binding	Molecular function	25416956
MSL2	55167	male-specific lethal 2 homolog (Drosophila)	nucleoplasm	Cellular component	-
CREBBP	1387	CREB binding protein	histone acetyltransferase activity	Molecular function	11742995
FGG	2266	fibrinogen gamma chain	external side of plasma membrane	Cellular component	6777381
SLC1A4	6509	solute carrier family 1 (glutamate/neutral amino acid transporter), member 4	dendrite	Cellular component	-
PDK1	5163	pyruvate dehydrogenase kinase, isozyme 1	protein phosphorylation	Biological process	22195962
ETS2	2114	v-ets avian erythroblastosis virus E26 oncogene homolog 2	transcription, DNA-templated	Biological process	-
BTK	695	Bruton agammaglobulinemia tyrosine kinase	adaptive immune response	Biological process	19290921
GOLGA3	2802	golgin A3	protein binding	Molecular function	14522980
AGT	183	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	response to cold	Biological process	-
CHST5	23563	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5	integral component of membrane	Cellular component	10491328
CEP290	80184	centrosomal protein 290kDa	retina development in camera-type eye	Biological process	-
SCOC	60592	short coiled-coil protein	cytosol	Cellular component	-
OR4A15	81328	olfactory receptor, family 4, subfamily A, member 15	G-protein coupled receptor signaling pathway	Biological process	-
VEGFB	7423	vascular endothelial growth factor B	extracellular space	Cellular component	12881472
BRINP2	57795	bone morphogenetic protein/retinoic acid inducible neural-specific 2	negative regulation of mitotic cell cycle	Biological process	-
DUSP22	56940	dual specificity phosphatase 22	cytoplasm	Cellular component	-
PTK2	5747	protein tyrosine kinase 2	JUN kinase binding	Molecular function	10925297
TPSAB1	7177	tryptase alpha/beta 1	extracellular matrix disassembly	Biological process	-
CLDN1	9076	claudin 1	integral component of plasma membrane	Cellular component	23407391
UBE2V1	7335	ubiquitin-conjugating enzyme E2 variant 1	Fc-epsilon receptor signaling pathway	Biological process	-
EXOSC7	23016	exosome component 7	cytosol	Cellular component	-
PAX2	5076	paired box 2	transcription regulatory region DNA binding	Molecular function	16368682
FGF10	2255	fibroblast growth factor 10	metanephros development	Biological process	18437684
RPL15	6138	ribosomal protein L15	viral process	Biological process	-
PRKAR1B	5575	protein kinase, cAMP-dependent, regulatory, type I, beta	cellular response to glucagon stimulus	Biological process	-
LGR6	59352	leucine-rich repeat containing G protein-coupled receptor 6	plasma membrane	Cellular component	-
AREG	374	amphiregulin	positive regulation of phosphorylation	Biological process	-
NCOA1	8648	nuclear receptor coactivator 1	small molecule metabolic process	Biological process	-
RHBG	57127	Rh family, B glycoprotein (gene/pseudogene)	integral component of plasma membrane	Cellular component	11024028
TEKT1	83659	tektin 1	cilium	Cellular component	-
SYNDIG1	79953	synapse differentiation inducing 1	excitatory synapse	Cellular component	-
GBF1	8729	golgi brefeldin A resistant guanine nucleotide exchange factor 1	Golgi disassembly	Biological process	23418352
TPM4	7171	tropomyosin 4	movement of cell or subcellular component	Biological process	16130169
SKI	6497	SKI proto-oncogene	nuclear body	Cellular component	12874272
CYBA	1535	cytochrome b-245, alpha polypeptide	protein heterodimerization activity	Molecular function	12042318
KIT	3815	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	protein homodimerization activity	Molecular function	21640708
WDR36	134430	WD repeat domain 36	nucleolus	Cellular component	-
ADIPOR1	51094	adiponectin receptor 1	receptor activity	Molecular function	-
CEBPG	1054	CCAAT/enhancer binding protein (C/EBP), gamma	transcription, DNA-templated	Biological process	-
FHOD3	80206	formin homology 2 domain containing 3	Z disc	Cellular component	-
BLOC1S3	388552	biogenesis of lysosomal organelles complex-1, subunit 3	platelet activation	Biological process	16385460
C5orf64	285668	chromosome 5 open reading frame 64	extracellular region	Cellular component	-
ZNF467	168544	zinc finger protein 467	metal ion binding	Molecular function	-
CADPS	8618	Ca++-dependent secretion activator	protein kinase binding	Molecular function	-
SPTBN1	6711	spectrin, beta, non-erythrocytic 1	mitotic cytokinesis	Biological process	17620337
JAK2	3717	Janus kinase 2	nucleoplasm	Cellular component	-
IST1	9798	increased sodium tolerance 1 homolog (yeast)	viral capsid secondary envelopment	Biological process	19129479
LCE3C	353144	late cornified envelope 3C	keratinization	Biological process	-
GPD2	2820	glycerol-3-phosphate dehydrogenase 2 (mitochondrial)	small molecule metabolic process	Biological process	-
ARHGEF2	9181	Rho/Rac guanine nucleotide exchange factor (GEF) 2	small GTPase mediated signal transduction	Biological process	-
CCDC8	83987	coiled-coil domain containing 8	plasma membrane	Cellular component	-
GDAP1	54332	ganglioside induced differentiation associated protein 1	mitochondrion	Cellular component	-
S100A4	6275	S100 calcium binding protein A4	identical protein binding	Molecular function	-
DLG3	1741	discs, large homolog 3 (Drosophila)	protein binding	Molecular function	19118189
ZNF444	55311	zinc finger protein 444	metal ion binding	Molecular function	-
UBC	7316	ubiquitin C	apoptotic process	Biological process	-
PRKCD	5580	protein kinase C, delta	peptidyl-tyrosine phosphorylation	Biological process	-
TJP2	9414	tight junction protein 2	response to organic substance	Biological process	-
WTIP	126374	Wilms tumor 1 interacting protein	negative regulation of nucleic acid-templated transcription	Biological process	-
NPAS3	64067	neuronal PAS domain protein 3	signal transducer activity	Molecular function	-
DUSP2	1844	dual specificity phosphatase 2	peptidyl-tyrosine dephosphorylation	Biological process	7681221
PIAS3	10401	protein inhibitor of activated STAT, 3	dendrite	Cellular component	-
COMMD9	29099	COMM domain containing 9	nucleus	Cellular component	-
NQO1	1728	NAD(P)H dehydrogenase, quinone 1	cytochrome-b5 reductase activity, acting on NAD(P)H	Molecular function	9579781
BRMS1L	84312	breast cancer metastasis-suppressor 1-like	histone deacetylase binding	Molecular function	-
STAP1	26228	signal transducing adaptor family member 1	positive regulation of actin cytoskeleton reorganization	Biological process	-
PRKCE	5581	protein kinase C, epsilon	activation of phospholipase C activity	Biological process	-
ITGB2	3689	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	positive regulation of angiogenesis	Biological process	-
DUSP6	1848	dual specificity phosphatase 6	toll-like receptor TLR6:TLR2 signaling pathway	Biological process	-
CD180	4064	CD180 molecule	cellular response to lipopolysaccharide	Biological process	-
INPPL1	3636	inositol polyphosphate phosphatase-like 1	cell adhesion	Biological process	15668240
ACTN2	88	actinin, alpha 2	blood coagulation	Biological process	-
DTX3	196403	deltex 3, E3 ubiquitin ligase	protein binding	Molecular function	25416956
ACOT4	122970	acyl-CoA thioesterase 4	succinyl-CoA hydrolase activity	Molecular function	16141203
SLCO1C1	53919	solute carrier organic anion transporter family, member 1C1	thyroid hormone transport	Biological process	-
MICAL2	9645	microtubule associated monooxygenase, calponin and LIM domain containing 2	actin binding	Molecular function	-
KDM5B	10765	lysine (K)-specific demethylase 5B	oxidation-reduction process	Biological process	-
PTPRG	5793	protein tyrosine phosphatase, receptor type, G	negative regulation of neuron projection development	Biological process	-
WASH3P	374666	WAS protein family homolog 3 pseudogene	early endosome membrane	Cellular component	-
NME6	10201	NME/NM23 nucleoside diphosphate kinase 6	mitochondrion	Cellular component	10618642
PODXL	5420	podocalyxin-like	negative regulation of cell adhesion	Biological process	-
PPAP2B	8613	phosphatidic acid phosphatase type 2B	regulation of sphingolipid mediated signaling pathway	Biological process	-
ZNF341	84905	zinc finger protein 341	transcription, DNA-templated	Biological process	-
DYNLL1	8655	dynein, light chain, LC8-type 1	apoptotic process	Biological process	-
INA	9118	internexin neuronal intermediate filament protein, alpha	cell differentiation	Biological process	-
MYH9	4627	myosin, heavy chain 9, non-muscle	ruffle	Cellular component	16403913
RBM25	58517	RNA binding motif protein 25	nucleoplasm	Cellular component	-
PBX1	5087	pre-B-cell leukemia homeobox 1	embryonic limb morphogenesis	Biological process	-
CCL2	6347	chemokine (C-C motif) ligand 2	rough endoplasmic reticulum	Cellular component	-
AKT1	207	v-akt murine thymoma viral oncogene homolog 1	programmed cell death	Biological process	-
SLC35B2	347734	solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2	Golgi apparatus	Cellular component	12716889
MAP2K6	5608	mitogen-activated protein kinase kinase 6	protein kinase binding	Molecular function	11279118
FZD8	8325	frizzled class receptor 8	positive regulation of JUN kinase activity	Biological process	-
ERN1	2081	endoplasmic reticulum to nucleus signaling 1	protein homodimerization activity	Molecular function	21317875
MGST1	4257	microsomal glutathione S-transferase 1	response to drug	Biological process	-
LRRK2	120892	leucine-rich repeat kinase 2	intracellular distribution of mitochondria	Biological process	21159966
KLRC4-KLRK1	100528032	KLRC4-KLRK1 readthrough	positive regulation of natural killer cell mediated cytotoxicity	Biological process	15294961
TNK2	10188	tyrosine kinase, non-receptor, 2	peptidyl-tyrosine autophosphorylation	Biological process	-
TDP2	51567	tyrosyl-DNA phosphodiesterase 2	nucleolus	Cellular component	-
ADAM19	8728	ADAM metallopeptidase domain 19	integral component of membrane	Cellular component	-
ECE1	1889	endothelin converting enzyme 1	metalloendopeptidase activity	Molecular function	8062389
DYNLT1	6993	dynein, light chain, Tctex-type 1	mitotic nuclear division	Biological process	-
EIF3D	8664	eukaryotic translation initiation factor 3, subunit D	cytosol	Cellular component	-
ZNF584	201514	zinc finger protein 584	nucleus	Cellular component	-
ITGA2B	3674	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	protein binding	Molecular function	14681217
PTPN6	5777	protein tyrosine phosphatase, non-receptor type 6	cytoplasm	Cellular component	10940933
SERPINB2	5055	serpin peptidase inhibitor, clade B (ovalbumin), member 2	negative regulation of apoptotic process	Biological process	-
RAB15	376267	RAB15, member RAS oncogene family	GTP binding	Molecular function	-
NUPL2	11097	nucleoporin like 2	viral process	Biological process	-
ACAT1	38	acetyl-CoA acetyltransferase 1	liver development	Biological process	-
BCAP31	10134	B-cell receptor-associated protein 31	cytosol	Cellular component	-
RLTPR	146206	RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing	F-actin capping protein complex	Cellular component	-
OR10J3	441911	olfactory receptor, family 10, subfamily J, member 3	plasma membrane	Cellular component	-
HIST1H4F	8361	histone cluster 1, H4f	negative regulation of megakaryocyte differentiation	Biological process	18474616
TRIM22	10346	tripartite motif containing 22	immune response	Biological process	7797467
NTRK3	4916	neurotrophic tyrosine kinase, receptor, type 3	protein autophosphorylation	Biological process	-
HOXC10	3226	homeobox C10	embryonic limb morphogenesis	Biological process	-
ITPR3	3710	inositol 1,4,5-trisphosphate receptor, type 3	innate immune response	Biological process	-
PLA2G2A	5320	phospholipase A2, group IIA (platelets, synovial fluid)	endoplasmic reticulum membrane	Cellular component	-
CPSF6	11052	cleavage and polyadenylation specific factor 6, 68kDa	mRNA binding	Molecular function	21295486
WNT3	7473	wingless-type MMTV integration site family, member 3	canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation	Biological process	20039315
PARD6A	50855	par-6 family cell polarity regulator alpha	transcription factor binding	Molecular function	9482110
ENAH	55740	enabled homolog (Drosophila)	T cell receptor signaling pathway	Biological process	-
UNC5D	137970	unc-5 homolog D (C. elegans)	regulation of neuron migration	Biological process	-
DYNC1LI1	51143	dynein, cytoplasmic 1, light intermediate chain 1	viral process	Biological process	-
MTHFR	4524	methylenetetrahydrofolate reductase (NAD(P)H)	protein complex binding	Molecular function	24769206
HNRNPH1	3187	heterogeneous nuclear ribonucleoprotein H1 (H)	RNA processing	Biological process	7499401
CCL8	6355	chemokine (C-C motif) ligand 8	cell-cell signaling	Biological process	10734056
SERPINB6	5269	serpin peptidase inhibitor, clade B (ovalbumin), member 6	cellular response to osmotic stress	Biological process	20451170
KRT85	3891	keratin 85, type II	structural molecule activity	Molecular function	-
PGM1	5236	phosphoglucomutase 1	phosphoglucomutase activity	Molecular function	8257433
MAFA	389692	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A	protein homodimerization activity	Molecular function	12368292
PTTG1IP	754	pituitary tumor-transforming 1 interacting protein	p53 binding	Molecular function	24506068
RNF148	378925	ring finger protein 148	zinc ion binding	Molecular function	-
ZG16	653808	zymogen granule protein 16	protein transport	Biological process	17307141
AICDA	57379	activation-induced cytidine deaminase	B cell differentiation	Biological process	11007475
TRAF6	7189	TNF receptor-associated factor 6, E3 ubiquitin protein ligase	apoptotic signaling pathway	Biological process	-
TACC3	10460	transforming, acidic coiled-coil containing protein 3	neurogenesis	Biological process	-
INIP	58493	INTS3 and NABP interacting protein	cellular response to DNA damage stimulus	Biological process	19683501
FGF22	27006	fibroblast growth factor 22	growth factor activity	Molecular function	-
RUNX2	860	runt-related transcription factor 2	chondrocyte development	Biological process	-
RC3H2	54542	ring finger and CCCH-type domains 2	nucleoplasm	Cellular component	-
WHSC1L1	54904	Wolf-Hirschhorn syndrome candidate 1-like 1	protein binding	Molecular function	23455924
MECOM	2122	MDS1 and EVI1 complex locus	cell differentiation	Biological process	-
HIST1H2AL	8332	histone cluster 1, H2al	nucleosome	Cellular component	-
ZNF440	126070	zinc finger protein 440	protein binding	Molecular function	16189514
EIF4B	1975	eukaryotic translation initiation factor 4B	cytosol	Cellular component	-
PINX1	54984	PIN2/TERF1 interacting, telomerase inhibitor 1	negative regulation of telomerase activity	Biological process	15381700
BMPR1A	657	bone morphogenetic protein receptor, type IA	protein serine/threonine kinase activity	Molecular function	12065756
EGR2	1959	early growth response 2	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	12687019
OR2A2	442361	olfactory receptor, family 2, subfamily A, member 2	plasma membrane	Cellular component	-
TBX2	6909	T-box 2	embryonic camera-type eye morphogenesis	Biological process	-
Mar-09	92979	membrane-associated ring finger (C3HC4) 9	protein ubiquitination	Biological process	-
CASP6	839	caspase 6, apoptosis-related cysteine peptidase	cysteine-type peptidase activity	Molecular function	7796396
BAK1	578	BCL2-antagonist/killer 1	BH domain binding	Molecular function	-
MGEA5	10724	meningioma expressed antigen 5 (hyaluronidase)	protein deglycosylation	Biological process	11148210
NFKB2	4791	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	chromatin binding	Molecular function	-
CTSH	1512	cathepsin H	alveolar lamellar body	Cellular component	18216060
LGMN	5641	legumain	proteolysis	Biological process	-
INVS	27130	inversin	negative regulation of canonical Wnt signaling pathway	Biological process	18371931
RAN	5901	RAN, member RAS oncogene family	protein export from nucleus	Biological process	16449645
DBI	1622	diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)	phosphatidylcholine acyl-chain remodeling	Biological process	21079819
KAT8	84148	K(lysine) acetyltransferase 8	nuclear membrane	Cellular component	-
MITF	4286	microphthalmia-associated transcription factor	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	24769727
STAU1	6780	staufen double-stranded RNA binding protein 1	plasma membrane	Cellular component	22978549
HOMER2	9455	homer scaffolding protein 2	dendrite	Cellular component	-
RPL9	6133	ribosomal protein L9	RNA binding	Molecular function	8597601
VPS37B	79720	vacuolar protein sorting 37 homolog B (S. cerevisiae)	protein binding	Molecular function	15218037
F10	2159	coagulation factor X	post-translational protein modification	Biological process	-
SFRP1	6422	secreted frizzled-related protein 1	hematopoietic progenitor cell differentiation	Biological process	19778523
TNRC6A	27327	trinucleotide repeat containing 6A	Notch signaling pathway	Biological process	-
CHAF1B	8208	chromatin assembly factor 1, subunit B (p60)	activation of mitophagy in response to mitochondrial depolarization	Biological process	22020285
RB1	5925	retinoblastoma 1	regulation of lipid kinase activity	Biological process	16286473
DLD	1738	dihydrolipoamide dehydrogenase	lysine catabolic process	Biological process	-
PAX4	5078	paired box 4	RNA polymerase II distal enhancer sequence-specific DNA binding	Molecular function	-
CNTN2	6900	contactin 2 (axonal)	neuronal cell body	Cellular component	-
BSPRY	54836	B-box and SPRY domain containing	focal adhesion	Cellular component	-
NR1H4	9971	nuclear receptor subfamily 1, group H, member 4	protein binding	Molecular function	12917342
TOX	9760	thymocyte selection-associated high mobility group box	DNA binding	Molecular function	-
ADAM17	6868	ADAM metallopeptidase domain 17	cell adhesion mediated by integrin	Biological process	14970227
NOG	9241	noggin	positive regulation of branching involved in ureteric bud morphogenesis	Biological process	-
AHSA2	130872	AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast)	protein binding	Molecular function	25416956
RUFY4	285180	RUN and FYVE domain containing 4	metal ion binding	Molecular function	-
SRSF5	6430	serine/arginine-rich splicing factor 5	mRNA export from nucleus	Biological process	-
HDAC1	3065	histone deacetylase 1	viral process	Biological process	-
KIF17	57576	kinesin family member 17	microtubule binding	Molecular function	-
TPMT	7172	thiopurine S-methyltransferase	methylation	Biological process	-
AKT1	207	v-akt murine thymoma viral oncogene homolog 1	protein serine/threonine kinase activity	Molecular function	21432781
AP1S3	130340	adaptor-related protein complex 1, sigma 3 subunit	protein targeting	Biological process	24791904
IL1B	3553	interleukin 1, beta	positive regulation of calcidiol 1-monooxygenase activity	Biological process	16720713
SFPQ	6421	splicing factor proline/glutamine-rich	protein binding	Molecular function	10653975
RPE65	6121	retinal pigment epithelium-specific protein 65kDa	vitamin A metabolic process	Biological process	9326941
ARG1	383	arginase 1	cellular nitrogen compound metabolic process	Biological process	-
RHBDF1	64285	rhomboid 5 homolog 1 (Drosophila)	protein processing	Biological process	-
CCL16	6360	chemokine (C-C motif) ligand 16	chemoattractant activity	Molecular function	15001559
SNX31	169166	sorting nexin 31	protein transport	Biological process	-
MED16	10025	mediator complex subunit 16	positive regulation of transcription, DNA-templated	Biological process	10198638
TINF2	26277	TERF1 (TRF1)-interacting nuclear factor 2	negative regulation of protein ADP-ribosylation	Biological process	15133513
CORO1C	23603	coronin, actin binding protein, 1C	flotillin complex	Cellular component	-
HBB	3043	hemoglobin, beta	hydrogen peroxide catabolic process	Biological process	19740759
LIMA1	51474	LIM domain and actin binding 1	actin filament bundle assembly	Biological process	12566430
IKBKE	9641	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	toll-like receptor signaling pathway	Biological process	-
LARGE	9215	like-glycosyltransferase	skeletal muscle organ development	Biological process	-
ARNTL	406	aryl hydrocarbon receptor nuclear translocator-like	regulation of insulin secretion	Biological process	-
DHRS7B	25979	dehydrogenase/reductase (SDR family) member 7B	oxidoreductase activity	Molecular function	-
KIR2DL1	3802	killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1	natural killer cell inhibitory signaling pathway	Biological process	18604210
TNC	3371	tenascin C	neuromuscular junction development	Biological process	-
TUBA1C	84790	tubulin, alpha 1c	protein folding	Biological process	-
P2RX1	5023	purinergic receptor P2X, ligand gated ion channel, 1	plasma membrane	Cellular component	-
OR4A16	81327	olfactory receptor, family 4, subfamily A, member 16	detection of chemical stimulus involved in sensory perception	Biological process	-
SUGP1	57794	SURP and G patch domain containing 1	RNA splicing	Biological process	-
BEST1	7439	bestrophin 1	integral component of membrane	Cellular component	10737974
DIAPH3	81624	diaphanous-related formin 3	Rho GTPase binding	Molecular function	-
BID	637	BH3 interacting domain death agonist	membrane	Cellular component	8918887
SGCE	8910	sarcoglycan, epsilon	plasma membrane	Cellular component	-
ZNF540	163255	zinc finger protein 540	sequence-specific DNA binding transcription factor activity	Molecular function	-
AKT1	207	v-akt murine thymoma viral oncogene homolog 1	positive regulation of cell growth	Biological process	19203586
RAB39A	54734	RAB39A, member RAS oncogene family	phagosome-lysosome fusion	Biological process	21255211
RUVBL1	8607	RuvB-like AAA ATPase 1	microtubule organizing center	Cellular component	-
DHX9	1660	DEAH (Asp-Glu-Ala-His) box helicase 9	ribonucleoprotein complex	Cellular component	17289661
NOX4	50507	NADPH oxidase 4	superoxide anion generation	Biological process	10869423
MMP26	56547	matrix metallopeptidase 26	collagen catabolic process	Biological process	-
IMPG1	3617	interphotoreceptor matrix proteoglycan 1	proteinaceous extracellular matrix	Cellular component	9691169
DRD1	1812	dopamine receptor D1	dopamine binding	Molecular function	1282671
PKD2	5311	polycystic kidney disease 2 (autosomal dominant)	renal tubule morphogenesis	Biological process	-
NCKAP1	10787	NCK-associated protein 1	extracellular exosome	Cellular component	19056867
NOG	9241	noggin	neural plate morphogenesis	Biological process	-
GLIS2	84662	GLIS family zinc finger 2	negative regulation of transcription, DNA-templated	Biological process	-
JUNB	3726	jun B proto-oncogene	trophectodermal cell differentiation	Biological process	-
FOXH1	8928	forkhead box H1	cardiac right ventricle morphogenesis	Biological process	-
RPS15A	6210	ribosomal protein S15a	translational elongation	Biological process	-
SUMF1	285362	sulfatase modifying factor 1	cellular protein metabolic process	Biological process	-
B3GAT3	26229	beta-1,3-glucuronyltransferase 3	protein glycosylation	Biological process	-
NUP188	23511	nucleoporin 188kDa	glucose transport	Biological process	-
KCNC3	3748	potassium channel, voltage gated Shaw related subfamily C, member 3	integral component of membrane	Cellular component	-
AMBP	259	alpha-1-microglobulin/bikunin precursor	cell adhesion	Biological process	9570066
PSMC4	5704	proteasome (prosome, macropain) 26S subunit, ATPase, 4	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
GSG1L	146395	GSG1-like	asymmetric synapse	Cellular component	-
EMD	2010	emerin	positive regulation of protein export from nucleus	Biological process	16858403
ELP4	26610	elongator acetyltransferase complex subunit 4	regulation of protein kinase activity	Biological process	11818576
INSC	387755	inscuteable homolog (Drosophila)	nervous system development	Biological process	-
UBE2J1	51465	ubiquitin-conjugating enzyme E2, J1	protein N-linked glycosylation via asparagine	Biological process	22607976
P2RX3	5024	purinergic receptor P2X, ligand gated ion channel, 3	extracellular ATP-gated cation channel activity	Molecular function	17895406
APOH	350	apolipoprotein H (beta-2-glycoprotein I)	phospholipid binding	Molecular function	15486070
RPL27A	6157	ribosomal protein L27a	gene expression	Biological process	-
KCNMA1	3778	potassium channel, calcium activated large conductance subfamily M alpha, member 1	synaptic transmission	Biological process	-
EPN1	29924	epsin 1	protein binding	Molecular function	18199683
MGST3	4259	microsomal glutathione S-transferase 3	protein binding	Molecular function	25416956
TJAP1	93643	tight junction associated protein 1 (peripheral)	bicellular tight junction	Cellular component	-
KRT39	390792	keratin 39, type I	intermediate filament	Cellular component	-
RPL36A	6173	ribosomal protein L36a	SRP-dependent cotranslational protein targeting to membrane	Biological process	-
RAB9A	9367	RAB9A, member RAS oncogene family	phagocytic vesicle membrane	Cellular component	-
PROK2	60675	prokineticin 2	G-protein coupled receptor signaling pathway	Biological process	11259612
CENPE	1062	centromere protein E, 312kDa	microtubule motor activity	Molecular function	7889940
ACACA	31	acetyl-CoA carboxylase alpha	cytoplasm	Cellular component	-
PITX2	5308	paired-like homeodomain 2	transcription from RNA polymerase II promoter	Biological process	-
HLF	3131	hepatic leukemia factor	regulation of transcription, DNA-templated	Biological process	-
MYBBP1A	10514	MYB binding protein (P160) 1a	protein binding	Molecular function	-
XPC	7508	xeroderma pigmentosum, complementation group C	nucleolus	Cellular component	-
SOX5	6660	SRY (sex determining region Y)-box 5	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
BSG	682	basigin (Ok blood group)	membrane	Cellular component	19946888
FAM26E	254228	family with sequence similarity 26, member E	integral component of plasma membrane	Cellular component	-
ITGA5	3678	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	leukocyte cell-cell adhesion	Biological process	-
LSM10	84967	LSM10, U7 small nuclear RNA associated	termination of RNA polymerase II transcription	Biological process	-
VPS37C	55048	vacuolar protein sorting 37 homolog C (S. cerevisiae)	endosomal transport	Biological process	-
PNRC2	55629	proline-rich nuclear receptor coactivator 2	deadenylation-independent decapping of nuclear-transcribed mRNA	Biological process	19150429
ITGA2B	3674	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	external side of plasma membrane	Cellular component	-
COL28A1	340267	collagen, type XXVIII, alpha 1	endoplasmic reticulum lumen	Cellular component	-
SNX8	29886	sorting nexin 8	retromer complex	Cellular component	19782049
TIPIN	54962	TIMELESS interacting protein	nuclear chromatin	Cellular component	17102137
OR4C12	283093	olfactory receptor, family 4, subfamily C, member 12	integral component of membrane	Cellular component	-
BMP15	9210	bone morphogenetic protein 15	BMP signaling pathway	Biological process	-
RASGRF2	5924	Ras protein-specific guanine nucleotide-releasing factor 2	small GTPase mediated signal transduction	Biological process	-
DCAF6	55827	DDB1 and CUL4 associated factor 6	cytoplasm	Cellular component	-
LCE3E	353145	late cornified envelope 3E	keratinization	Biological process	-
HTRA3	94031	HtrA serine peptidase 3	negative regulation of transforming growth factor beta receptor signaling pathway	Biological process	-
UBE2G1	7326	ubiquitin-conjugating enzyme E2G 1	extracellular exosome	Cellular component	19056867
PDZD11	51248	PDZ domain containing 11	protein C-terminus binding	Molecular function	12763866
ABHD6	57406	abhydrolase domain containing 6	extracellular exosome	Cellular component	23376485
MMS19	64210	MMS19 nucleotide excision repair homolog (S. cerevisiae)	membrane	Cellular component	19946888
LONP1	9361	lon peptidase 1, mitochondrial	G-quadruplex DNA binding	Molecular function	18174225
MECP2	4204	methyl CpG binding protein 2	proprioception	Biological process	-
GOPC	57120	golgi-associated PDZ and coiled-coil motif containing	protein homooligomerization	Biological process	11707463
ICAM1	3383	intercellular adhesion molecule 1	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	Biological process	2477710
ANK2	287	ankyrin 2, neuronal	regulation of cardiac muscle cell contraction	Biological process	17242276
FGF7	2252	fibroblast growth factor 7	Fc-epsilon receptor signaling pathway	Biological process	-
MGST2	4258	microsomal glutathione S-transferase 2	intracellular membrane-bounded organelle	Cellular component	8703034
HTR1E	3354	5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled	synaptic transmission	Biological process	-
CSF3	1440	colony stimulating factor 3 (granulocyte)	positive regulation of phosphatidylinositol 3-kinase signaling	Biological process	23001182
PSPH	5723	phosphoserine phosphatase	response to nutrient levels	Biological process	-
CTNNA2	1496	catenin (cadherin-associated protein), alpha 2	brain morphogenesis	Biological process	-
GGT5	2687	gamma-glutamyltransferase 5	glutathione hydrolase activity	Molecular function	-
NOSTRIN	115677	nitric oxide synthase trafficking	nucleus	Cellular component	-
IAH1	285148	isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)	lipid catabolic process	Biological process	-
TADA1	117143	transcriptional adaptor 1	cytoplasm	Cellular component	-
CCL26	10344	chemokine (C-C motif) ligand 26	extracellular space	Cellular component	-
CXADR	1525	coxsackie virus and adenovirus receptor	PDZ domain binding	Molecular function	15364909
SOD1	6647	superoxide dismutase 1, soluble	dendrite cytoplasm	Cellular component	17324120
CAV1	857	caveolin 1, caveolae protein, 22kDa	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
KATNB1	10300	katanin p80 (WD repeat containing) subunit B 1	positive regulation of neuron projection development	Biological process	-
PDIA3	2923	protein disulfide isomerase family A, member 3	extracellular exosome	Cellular component	19199708
ADGRE5	976	adhesion G protein-coupled receptor E5	immune response	Biological process	7636245
SKIV2L2	23517	superkiller viralicidic activity 2-like 2 (S. cerevisiae)	catalytic step 2 spliceosome	Cellular component	11991638
BAIAP2L1	55971	BAI1-associated protein 2-like 1	proline-rich region binding	Molecular function	21098279
MMP13	4322	matrix metallopeptidase 13	calcium ion binding	Molecular function	23913860
EREG	2069	epiregulin	positive regulation of epidermal growth factor-activated receptor activity	Biological process	9990076
BRINP1	1620	bone morphogenetic protein/retinoic acid inducible neural-specific 1	cell death	Biological process	14712213
RPL27A	6157	ribosomal protein L27a	viral process	Biological process	-
MYLK3	91807	myosin light chain kinase 3	regulation of vascular permeability involved in acute inflammatory response	Biological process	18390750
TLE4	7091	transducin-like enhancer of split 4	repressing transcription factor binding	Molecular function	-
SLC17A7	57030	solute carrier family 17 (vesicular glutamate transporter), member 7	sequestering of neurotransmitter	Biological process	-
GNAQ	2776	guanine nucleotide binding protein (G protein), q polypeptide	regulation of catenin import into nucleus	Biological process	20399743
PADI6	353238	peptidyl arginine deiminase, type VI	protein-arginine deiminase activity	Molecular function	-
SPAG1	6674	sperm associated antigen 1	metabolic process	Biological process	-
CD1D	912	CD1d molecule	positive regulation of T cell proliferation	Biological process	19124746
HBA1	3039	hemoglobin, alpha 1	oxygen transport	Biological process	7518430
TAF9B	51616	TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa	transcription from RNA polymerase II promoter	Biological process	-
PGK2	5232	phosphoglycerate kinase 2	sperm fibrous sheath	Cellular component	-
MMP19	4327	matrix metallopeptidase 19	extracellular matrix disassembly	Biological process	-
HSD17B10	3028	hydroxysteroid (17-beta) dehydrogenase 10	oxidation-reduction process	Biological process	-
ZNF729	100287226	zinc finger protein 729	DNA binding	Molecular function	-
ATP1B2	482	ATPase, Na+/K+ transporting, beta 2 polypeptide	transport	Biological process	2538450
CEP295	85459	centrosomal protein 295kDa	positive regulation of organelle assembly	Biological process	25131205
APH1A	51107	APH1A gamma secretase subunit	neurotrophin TRK receptor signaling pathway	Biological process	-
ABCD1	215	ATP-binding cassette, sub-family D (ALD), member 1	perinuclear region of cytoplasm	Cellular component	17761426
SLC7A4	6545	solute carrier family 7, member 4	L-lysine transmembrane transporter activity	Molecular function	-
TGFBR1	7046	transforming growth factor, beta receptor 1	regulation of epithelial to mesenchymal transition	Biological process	-
SERPINH1	871	serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)	membrane raft	Cellular component	25204797
PEX19	5824	peroxisomal biogenesis factor 19	peroxisome membrane biogenesis	Biological process	10051604
EXOSC3	51010	exosome component 3	nucleus	Cellular component	17545563
SENP2	59343	SUMO1/sentrin/SMT3 specific peptidase 2	spongiotrophoblast layer development	Biological process	-
EDNRB	1910	endothelin receptor type B	cellular response to lipopolysaccharide	Biological process	-
SYT4	6860	synaptotagmin IV	negative regulation of vesicle fusion	Biological process	-
TM6SF2	53345	transmembrane 6 superfamily member 2	regulation of lipid metabolic process	Biological process	24927523
PDP2	57546	pyruvate dehyrogenase phosphatase catalytic subunit 2	peptidyl-threonine dephosphorylation	Biological process	-
PLSCR4	57088	phospholipid scramblase 4	extracellular exosome	Cellular component	23376485
MITF	4286	microphthalmia-associated transcription factor	bone remodeling	Biological process	-
ARHGAP35	2909	Rho GTPase activating protein 35	negative regulation of vascular permeability	Biological process	-
PLEK	5341	pleckstrin	negative regulation of calcium-mediated signaling	Biological process	8999861
HESX1	8820	HESX homeobox 1	transcription, DNA-templated	Biological process	-
VLDLR	7436	very low density lipoprotein receptor	reelin receptor activity	Molecular function	-
CHSY1	22856	chondroitin sulfate synthase 1	integral component of membrane	Cellular component	-
TTC30B	150737	tetratricopeptide repeat domain 30B	organelle organization	Biological process	-
ARHGAP22	58504	Rho GTPase activating protein 22	cytosol	Cellular component	-
DNM1P34	729809	dynamin 1 pseudogene 34	metabolic process	Biological process	-
LGALS3	3958	lectin, galactoside-binding, soluble, 3	immunological synapse	Cellular component	19706535
TUBB4A	10382	tubulin, beta 4A class IVa	cellular protein metabolic process	Biological process	-
FBXO25	26260	F-box protein 25	ubiquitin-protein transferase activity	Molecular function	10531035
OR2T33	391195	olfactory receptor, family 2, subfamily T, member 33	integral component of membrane	Cellular component	-
HCAR2	338442	hydroxycarboxylic acid receptor 2	G-protein coupled receptor signaling pathway	Biological process	-
AQP5	362	aquaporin 5	protein binding	Molecular function	16189514
SH3GL3	6457	SH3-domain GRB2-like 3	protein binding	Molecular function	15383276
CXCL16	58191	chemokine (C-X-C motif) ligand 16	low-density lipoprotein receptor activity	Molecular function	-
CENPQ	55166	centromere protein Q	mitotic cell cycle	Biological process	-
USP3	9960	ubiquitin specific peptidase 3	ubiquitin-specific protease activity	Molecular function	10480896
PPIB	5479	peptidylprolyl isomerase B (cyclophilin B)	bone development	Biological process	20089953
ERVH48-1	90625	endogenous retrovirus group 48, member 1	syncytium formation	Biological process	23492904
SCN1B	6324	sodium channel, voltage gated, type I beta subunit	voltage-gated sodium channel activity involved in cardiac muscle cell action potential	Molecular function	19808477
AIFM2	84883	apoptosis-inducing factor, mitochondrion-associated, 2	DNA binding	Molecular function	15958387
PRMT2	3275	protein arginine methyltransferase 2	protein homodimerization activity	Molecular function	12039952
KIF11	3832	kinesin family member 11	spindle microtubule	Cellular component	14718566
HDAC6	10013	histone deacetylase 6	histone H4 deacetylation	Biological process	-
MTR	4548	5-methyltetrahydrofolate-homocysteine methyltransferase	methylation	Biological process	-
CEBPD	1052	CCAAT/enhancer binding protein (C/EBP), delta	transcription from RNA polymerase II promoter	Biological process	8314590
OAZ3	51686	ornithine decarboxylase antizyme 3	negative regulation of polyamine transmembrane transport	Biological process	-
DRD5	1816	dopamine receptor D5	plasma membrane	Cellular component	-
CSPG4	1464	chondroitin sulfate proteoglycan 4	glycosaminoglycan metabolic process	Biological process	-
FGF8	2253	fibroblast growth factor 8 (androgen-induced)	fibroblast growth factor receptor binding	Molecular function	-
SYT13	57586	synaptotagmin XIII	synaptic vesicle exocytosis	Biological process	-
TP63	8626	tumor protein p63	proximal/distal pattern formation	Biological process	-
PPP2R5D	5528	protein phosphatase 2, regulatory subunit B', delta	toll-like receptor TLR6:TLR2 signaling pathway	Biological process	-
PUS1	80324	pseudouridylate synthase 1	nucleolus	Cellular component	-
SGPL1	8879	sphingosine-1-phosphate lyase 1	spermatogenesis	Biological process	-
PPARA	5465	peroxisome proliferator-activated receptor alpha	protein binding	Molecular function	11915042
ACTN1	87	actinin, alpha 1	actin crosslink formation	Biological process	-
LSM1	27257	LSM1, U6 small nuclear RNA associated	histone mRNA catabolic process	Biological process	18172165
PCNA	5111	proliferating cell nuclear antigen	protein binding	Molecular function	10873631
P2RX7	5027	purinergic receptor P2X, ligand gated ion channel, 7	cell-cell junction	Cellular component	-
MYADML2	255275	myeloid-associated differentiation marker-like 2	cytoplasm	Cellular component	21325632
FOXO3	2309	forkhead box O3	regulation of reactive oxygen species metabolic process	Biological process	-
PLA2G7	7941	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	cellular protein metabolic process	Biological process	-
ZBTB1	22890	zinc finger and BTB domain containing 1	innate immune response	Biological process	-
AARSD1	80755	alanyl-tRNA synthetase domain containing 1	ATP binding	Molecular function	-
SMAD4	4089	SMAD family member 4	positive regulation of SMAD protein import into nucleus	Biological process	-
RSC1A1	6248	regulatory solute carrier protein, family 1, member 1	intracellular membrane-bounded organelle	Cellular component	-
RAB14	51552	RAB14, member RAS oncogene family	GDP binding	Molecular function	16034420
USO1	8615	USO1 vesicle transport factor	mitotic cell cycle	Biological process	-
SERINC3	10955	serine incorporator 3	integral component of membrane	Cellular component	-
PIGB	9488	phosphatidylinositol glycan anchor biosynthesis, class B	endoplasmic reticulum membrane	Cellular component	-
FIS1	51024	fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)	peroxisome fission	Biological process	20826455
CRABP2	1382	cellular retinoic acid binding protein 2	cytosol	Cellular component	-
MAP3K5	4217	mitogen-activated protein kinase kinase kinase 5	protein kinase binding	Molecular function	-
STAR	6770	steroidogenic acute regulatory protein	protein binding	Molecular function	25416956
KLK8	11202	kallikrein-related peptidase 8	proteolysis	Biological process	-
E2F5	1875	E2F transcription factor 5, p130-binding	protein binding	Molecular function	16360038
CYP3A4	1576	cytochrome P450, family 3, subfamily A, polypeptide 4	intracellular membrane-bounded organelle	Cellular component	3460094
RAB27A	5873	RAB27A, member RAS oncogene family	protein binding	Molecular function	12897212
CREB3L3	84699	cAMP responsive element binding protein 3-like 3	nucleus	Cellular component	16469704
CST11	140880	cystatin 11	cytoplasm	Cellular component	-
LRRC37A	9884	leucine rich repeat containing 37A	integral component of membrane	Cellular component	-
ARAP1	116985	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1	positive regulation of receptor recycling	Biological process	-
BAG6	7917	BCL2-associated athanogene 6	lung development	Biological process	-
FAP	2191	fibroblast activation protein, alpha	negative regulation of extracellular matrix disassembly	Biological process	16651416
KIF24	347240	kinesin family member 24	metabolic process	Biological process	-
ENG	2022	endoglin	intracellular signal transduction	Biological process	12015308
ZFYVE27	118813	zinc finger, FYVE domain containing 27	metal ion binding	Molecular function	-
FURIN	5045	furin (paired basic amino acid cleaving enzyme)	negative regulation of low-density lipoprotein particle receptor catabolic process	Biological process	16912035
APOA2	336	apolipoprotein A-II	negative regulation of cholesterol transport	Biological process	8636092
GATB	5188	glutamyl-tRNA(Gln) amidotransferase, subunit B	glutamyl-tRNA(Gln) amidotransferase complex	Cellular component	19805282
ALKBH8	91801	alkB, alkylation repair homolog 8 (E. coli)	tRNA methylation	Biological process	20308323
CELF1	10658	CUGBP, Elav-like family member 1	mRNA splice site selection	Biological process	-
PRRX2	51450	paired related homeobox 2	cartilage development	Biological process	-
HLA-DQB2	3120	major histocompatibility complex, class II, DQ beta 2	immune response	Biological process	2564844
ORC6	23594	origin recognition complex, subunit 6	nucleus	Cellular component	-
XPNPEP3	63929	X-prolyl aminopeptidase 3, mitochondrial	aminopeptidase activity	Molecular function	20179356
FADD	8772	Fas (TNFRSF6)-associated via death domain	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	Biological process	-
DOCK7	85440	dedicator of cytokinesis 7	growth cone	Cellular component	16982419
NUP188	23511	nucleoporin 188kDa	viral transcription	Biological process	-
TAPBP	6892	TAP binding protein (tapasin)	TAP1 binding	Molecular function	12788224
ARSG	22901	arylsulfatase G	post-translational protein modification	Biological process	-
RNF111	54778	ring finger protein 111	protein ubiquitination	Biological process	16601693
PDXK	8566	pyridoxal (pyridoxine, vitamin B6) kinase	cytosol	Cellular component	-
PABPC1	26986	poly(A) binding protein, cytoplasmic 1	membrane	Cellular component	19946888
DPYS	1807	dihydropyrimidinase	thymine binding	Molecular function	-
SLC38A6	145389	solute carrier family 38, member 6	integral component of plasma membrane	Cellular component	-
IRAK3	11213	interleukin-1 receptor-associated kinase 3	negative regulation of MAP kinase activity	Biological process	17379480
RPL23A	6147	ribosomal protein L23a	cell proliferation	Biological process	9053844
CDKN3	1033	cyclin-dependent kinase inhibitor 3	protein tyrosine phosphatase activity	Molecular function	8242750
NT5C3A	51251	5'-nucleotidase, cytosolic IIIA	mitochondrion	Cellular component	-
PSMA6	5687	proteasome (prosome, macropain) subunit, alpha type, 6	proteasome core complex	Cellular component	1888762
S100A9	6280	S100 calcium binding protein A9	signal transducer activity	Molecular function	3313057
PML	5371	promyelocytic leukemia	regulation of transcription, DNA-templated	Biological process	23007646
MMP23B	8510	matrix metallopeptidase 23B	intracellular	Cellular component	9988691
E2F4	1874	E2F transcription factor 4, p107/p130-binding	protein domain specific binding	Molecular function	16360038
MLLT6	4302	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6	zinc ion binding	Molecular function	-
ARFIP1	27236	ADP-ribosylation factor interacting protein 1	trans-Golgi network membrane	Cellular component	23695357
PTPMT1	114971	protein tyrosine phosphatase, mitochondrial 1	small molecule metabolic process	Biological process	-
TFAP2C	7022	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	protein dimerization activity	Molecular function	12072434
UQCRC1	7384	ubiquinol-cytochrome c reductase core protein I	mitochondrial inner membrane	Cellular component	-
EDAR	10913	ectodysplasin A receptor	transmembrane signaling receptor activity	Molecular function	10431241
MTERF2	80298	mitochondrial transcription termination factor 2	transcription regulatory region DNA binding	Molecular function	-
CNKSR1	10256	connector enhancer of kinase suppressor of Ras 1	protein binding	Molecular function	16189514
NDUFB2	4708	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa	mitochondrial electron transport, NADH to ubiquinone	Biological process	9878551
NTRK3	4916	neurotrophic tyrosine kinase, receptor, type 3	integral component of plasma membrane	Cellular component	-
RPS27A	6233	ribosomal protein S27a	negative regulation of transforming growth factor beta receptor signaling pathway	Biological process	-
HIF1A	3091	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	B-1 B cell homeostasis	Biological process	-
PKD1	5310	polycystic kidney disease 1 (autosomal dominant)	neural tube development	Biological process	11891195
DLG3	1741	discs, large homolog 3 (Drosophila)	establishment of planar polarity	Biological process	-
GHITM	27069	growth hormone inducible transmembrane protein	apoptotic process	Biological process	-
DHFRL1	200895	dihydrofolate reductase-like 1	mitochondrial matrix	Cellular component	21876188
STAM	8027	signal transducing adaptor molecule (SH3 domain and ITAM motif) 1	signal transduction	Biological process	8780729
ZNF572	137209	zinc finger protein 572	nucleus	Cellular component	-
ARHGAP31	57514	Rho GTPase activating protein 31	focal adhesion	Cellular component	-
NFATC1	4772	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	G1/S transition of mitotic cell cycle	Biological process	-
PPP1R8	5511	protein phosphatase 1, regulatory subunit 8	protein binding	Molecular function	11739654
RPN1	6184	ribophorin I	protein N-linked glycosylation via asparagine	Biological process	15835887
UCP2	7351	uncoupling protein 2 (mitochondrial, proton carrier)	negative regulation of apoptotic process	Biological process	-
GABRP	2568	gamma-aminobutyric acid (GABA) A receptor, pi	signal transduction	Biological process	9182563
GDF1	2657	growth differentiation factor 1	regulation of apoptotic process	Biological process	-
EPS8	2059	epidermal growth factor receptor pathway substrate 8	postsynaptic density	Cellular component	-
ABCA3	21	ATP-binding cassette, sub-family A (ABC1), member 3	ATP binding	Molecular function	-
E2F8	79733	E2F transcription factor 8	cell cycle comprising mitosis without cytokinesis	Biological process	-
BMP7	655	bone morphogenetic protein 7	steroid hormone mediated signaling pathway	Biological process	17244894
VOPP1	81552	vesicular, overexpressed in cancer, prosurvival protein 1	endosome	Cellular component	-
SLA2	84174	Src-like-adaptor 2	antigen receptor-mediated signaling pathway	Biological process	11696592
SMAD2	4087	SMAD family member 2	co-SMAD binding	Molecular function	9111321
POLR2L	5441	polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa	transcription elongation from RNA polymerase II promoter	Biological process	-
CHMP6	79643	charged multivesicular body protein 6	cell separation after cytokinesis	Biological process	20616062
LRRD1	401387	leucine-rich repeats and death domain containing 1	signal transduction	Biological process	-
CD27	939	CD27 molecule	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	Molecular function	12324477
PSTPIP2	9050	proline-serine-threonine phosphatase interacting protein 2	membrane	Cellular component	-
MCCC2	64087	methylcrotonoyl-CoA carboxylase 2 (beta)	methylcrotonoyl-CoA carboxylase activity	Molecular function	11170888
CATSPER1	117144	cation channel, sperm associated 1	calcium activated cation channel activity	Molecular function	-
ERBB3	2065	erb-b2 receptor tyrosine kinase 3	plasma membrane	Cellular component	17701904
NBL1	4681	neuroblastoma 1, DAN family BMP antagonist	sequestering of BMP in extracellular matrix	Biological process	-
TGFB2	7042	transforming growth factor, beta 2	heart valve morphogenesis	Biological process	-
SHH	6469	sonic hedgehog	ventral midline development	Biological process	11001584
BCL2L12	83596	BCL2-like 12 (proline rich)	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	Biological process	-
ANGPT1	284	angiopoietin 1	regulation of satellite cell proliferation	Biological process	19733541
SERINC2	347735	serine incorporator 2	positive regulation of transferase activity	Biological process	-
TUBB	203068	tubulin, beta class I	structural constituent of cytoskeleton	Molecular function	-
CDKN1B	1027	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	protein complex binding	Molecular function	-
KIT	3815	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	activation of MAPK activity	Biological process	21640708
SENP1	29843	SUMO1/sentrin specific peptidase 1	cellular protein metabolic process	Biological process	-
ID2	3398	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	positive regulation of macrophage differentiation	Biological process	-
PARP1	142	poly (ADP-ribose) polymerase 1	base-excision repair	Biological process	-
LCP1	3936	lymphocyte cytosolic protein 1 (L-plastin)	T cell activation involved in immune response	Biological process	17294403
NIPBL	25836	Nipped-B homolog (Drosophila)	protein binding	Molecular function	16682347
UQCC1	55245	ubiquinol-cytochrome c reductase complex assembly factor 1	protein binding	Molecular function	24385928
CDK5R1	8851	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	positive regulation of neuron apoptotic process	Biological process	-
ANKRD26	22852	ankyrin repeat domain 26	glucose homeostasis	Biological process	-
RPL10A	4736	ribosomal protein L10a	viral process	Biological process	-
STMN4	81551	stathmin-like 4	axon	Cellular component	-
ZNF563	147837	zinc finger protein 563	metal ion binding	Molecular function	-
IARS	3376	isoleucyl-tRNA synthetase	isoleucine-tRNA ligase activity	Molecular function	-
RAD51D	5892	RAD51 paralog D	telomere maintenance	Biological process	15109494
CENPV	201161	centromere protein V	carbon-sulfur lyase activity	Molecular function	-
BICD1	636	bicaudal D homolog 1 (Drosophila)	dynein binding	Molecular function	12447383
PTK2B	2185	protein tyrosine kinase 2 beta	positive regulation of nitric-oxide synthase activity	Biological process	-
GATA5	140628	GATA binding protein 5	nucleoplasm	Cellular component	-
CENPE	1062	centromere protein E, 312kDa	midbody	Cellular component	2022189
FXR2	9513	fragile X mental retardation, autosomal homolog 2	protein binding	Molecular function	16189514
PDE3B	5140	phosphodiesterase 3B, cGMP-inhibited	cAMP catabolic process	Biological process	17884339
KRT10	3858	keratin 10, type I	structural constituent of epidermis	Molecular function	2459124
PTGDR	5729	prostaglandin D2 receptor (DP)	adenosine metabolic process	Biological process	-
NUP93	9688	nucleoporin 93kDa	viral transcription	Biological process	-
SLURP1	57152	secreted LY6/PLAUR domain containing 1	extracellular space	Cellular component	-
CLDN18	51208	claudin 18	bicellular tight junction	Cellular component	-
IL11	3589	interleukin 11	cytoplasm	Cellular component	-
ADRA1D	146	adrenoceptor alpha 1D	phospholipase C-activating G-protein coupled receptor signaling pathway	Biological process	-
DSG4	147409	desmoglein 4	hair follicle development	Biological process	-
GRIN1	2902	glutamate receptor, ionotropic, N-methyl D-aspartate 1	cation transport	Biological process	7685113
ARHGEF3	50650	Rho guanine nucleotide exchange factor (GEF) 3	positive regulation of GTPase activity	Biological process	10873612
GDNF	2668	glial cell derived neurotrophic factor	peristalsis	Biological process	-
ANAPC11	51529	anaphase promoting complex subunit 11	protein K11-linked ubiquitination	Biological process	18485873
C1QL4	338761	complement component 1, q subcomponent-like 4	negative regulation of ERK1 and ERK2 cascade	Biological process	-
SLC25A10	1468	solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10	transmembrane transport	Biological process	-
TANK	10010	TRAF family member-associated NFKB activator	toll-like receptor 4 signaling pathway	Biological process	-
MT1H	4496	metallothionein 1H	zinc ion binding	Molecular function	-
TGFBR3	7049	transforming growth factor, beta receptor III	cell surface	Cellular component	-
IFT81	28981	intraflagellar transport 81	intraciliary transport particle B	Cellular component	-
GZMH	2999	granzyme H (cathepsin G-like 2, protein h-CCPX)	cytoplasm	Cellular component	-
LST1	7940	leukocyte specific transcript 1	cytoplasm	Cellular component	11478849
SMYD1	150572	SET and MYND domain containing 1	metal ion binding	Molecular function	-
MPDZ	8777	multiple PDZ domain protein	bicellular tight junction	Cellular component	-
SKI	6497	SKI proto-oncogene	camera-type eye development	Biological process	-
TBX1	6899	T-box 1	cellular response to fibroblast growth factor stimulus	Biological process	-
CCAR1	55749	cell division cycle and apoptosis regulator 1	perinuclear region of cytoplasm	Cellular component	-
RALBP1	10928	ralA binding protein 1	signal transduction	Biological process	7673236
IKBKAP	8518	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein	RNA polymerase II core binding	Molecular function	11714725
DNM1L	10059	dynamin 1-like	mitochondrial fragmentation involved in apoptotic process	Biological process	12499352
PIF1	80119	PIF1 5'-to-3' DNA helicase	DNA duplex unwinding	Biological process	-
MOCS3	27304	molybdenum cofactor synthesis 3	URM1 activating enzyme activity	Molecular function	19017811
OR2T4	127074	olfactory receptor, family 2, subfamily T, member 4	G-protein coupled receptor activity	Molecular function	-
COMMD1	150684	copper metabolism (Murr1) domain containing 1	phosphatidylinositol-3,5-bisphosphate binding	Molecular function	18940794
NDST4	64579	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4	[heparan sulfate]-glucosamine N-sulfotransferase activity	Molecular function	-
CCR10	2826	chemokine (C-C motif) receptor 10	cytosol	Cellular component	-
THBS1	7057	thrombospondin 1	negative regulation of interleukin-12 production	Biological process	16882710
DUSP23	54935	dual specificity phosphatase 23	protein tyrosine phosphatase activity	Molecular function	-
TGFBR3	7049	transforming growth factor, beta receptor III	heart morphogenesis	Biological process	-
TKT	7086	transketolase	peroxisome	Cellular component	-
IFNE	338376	interferon, epsilon	B cell proliferation	Biological process	-
FXYD1	5348	FXYD domain containing ion transport regulator 1	sodium:potassium-exchanging ATPase complex	Cellular component	-
PLAT	5327	plasminogen activator, tissue	cytoplasm	Cellular component	1632457
CTSH	1512	cathepsin H	positive regulation of angiogenesis	Biological process	-
MEF2C	4208	myocyte enhancer factor 2C	renal tubule morphogenesis	Biological process	-
HDAC4	9759	histone deacetylase 4	regulation of gene expression, epigenetic	Biological process	24413532
ITGB1	3688	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	negative regulation of cell projection organization	Biological process	-
PPP1R15B	84919	protein phosphatase 1, regulatory subunit 15B	ER overload response	Biological process	-
SLC25A1	6576	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1	gluconeogenesis	Biological process	-
SLC25A42	284439	solute carrier family 25, member 42	nucleus	Cellular component	21630459
CTSE	1510	cathepsin E	antigen processing and presentation of exogenous peptide antigen via MHC class II	Biological process	8765029
EPB41L5	57669	erythrocyte membrane protein band 4.1 like 5	unidimensional cell growth	Biological process	-
ATG4D	84971	autophagy related 4D, cysteine peptidase	apoptotic process	Biological process	-
POLB	5423	polymerase (DNA directed), beta	protein complex	Cellular component	25378300
ACHE	43	acetylcholinesterase (Yt blood group)	synapse assembly	Biological process	11283752
EDNRA	1909	endothelin receptor type A	membrane raft	Cellular component	-
SIRT5	23408	sirtuin 5	protein deacetylation	Biological process	22076378
PDE11A	50940	phosphodiesterase 11A	cGMP catabolic process	Biological process	-
COBL	23242	cordon-bleu WH2 repeat protein	membrane	Cellular component	-
WNT5A	7474	wingless-type MMTV integration site family, member 5A	keratinocyte differentiation	Biological process	19399181
ZNF133	7692	zinc finger protein 133	transcription, DNA-templated	Biological process	-
LILRB2	10288	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	membrane	Cellular component	9079806
HNRNPK	3190	heterogeneous nuclear ribonucleoprotein K	single-stranded DNA binding	Molecular function	20371611
TAP2	6891	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	transmembrane transport	Biological process	-
ALOX5AP	241	arachidonate 5-lipoxygenase-activating protein	leukotriene metabolic process	Biological process	-
ADAM33	80332	ADAM metallopeptidase domain 33	zinc ion binding	Molecular function	11814695
GPX2	2877	glutathione peroxidase 2	cytoplasm	Cellular component	8428933
SPHK2	56848	sphingosine kinase 2	cytosol	Cellular component	-
DLL4	54567	delta-like 4 (Drosophila)	Notch signaling involved in heart development	Biological process	-
CAPN3	825	calpain 3, (p94)	response to calcium ion	Biological process	-
TNK1	8711	tyrosine kinase, non-receptor, 1	non-membrane spanning protein tyrosine kinase activity	Molecular function	10873601
APH1A	51107	APH1A gamma secretase subunit	endopeptidase activity	Molecular function	-
ESR2	2100	estrogen receptor 2 (ER beta)	estrogen response element binding	Molecular function	15345745
PPARG	5468	peroxisome proliferator-activated receptor gamma	negative regulation of acute inflammatory response	Biological process	-
OR4C11	219429	olfactory receptor, family 4, subfamily C, member 11	olfactory receptor activity	Molecular function	-
LARS	51520	leucyl-tRNA synthetase	methionine-tRNA ligase activity	Molecular function	-
PAX2	5076	paired box 2	positive regulation of optic nerve formation	Biological process	-
ASIC2	40	acid sensing (proton gated) ion channel 2	transmembrane transport	Biological process	-
CNTNAP1	8506	contactin associated protein 1	SH3/SH2 adaptor activity	Molecular function	9118959
STEAP1B	256227	STEAP family member 1B	copper ion import	Biological process	-
SRC	6714	SRC proto-oncogene, non-receptor tyrosine kinase	perinuclear region of cytoplasm	Cellular component	-
MED23	9439	mediator complex subunit 23	nucleoplasm	Cellular component	-
CFTR	1080	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	chloride transmembrane transport	Biological process	10581360
CALM1	801	calmodulin 1 (phosphorylase kinase, delta)	nitric-oxide synthase regulator activity	Molecular function	-
NDUFS8	4728	NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)	4 iron, 4 sulfur cluster binding	Molecular function	-
IDH2	3418	isocitrate dehydrogenase 2 (NADP+), mitochondrial	small molecule metabolic process	Biological process	-
NUP160	23279	nucleoporin 160kDa	cellular response to heat	Biological process	-
NOTCH1	4851	notch 1	positive regulation of cell migration	Biological process	-
PRSS41	360226	protease, serine, 41	anchored component of membrane	Cellular component	-
CPS1	1373	carbamoyl-phosphate synthase 1, mitochondrial	response to starvation	Biological process	-
RRP8	23378	ribosomal RNA processing 8, methyltransferase, homolog (yeast)	regulation of gene expression, epigenetic	Biological process	-
MLH1	4292	mutL homolog 1	intrinsic apoptotic signaling pathway in response to DNA damage	Biological process	-
CPT1A	1374	carnitine palmitoyltransferase 1A (liver)	carnitine O-palmitoyltransferase activity	Molecular function	11350182
SYF2	25949	SYF2 pre-mRNA-splicing factor	in utero embryonic development	Biological process	-
GALR3	8484	galanin receptor 3	positive regulation of transcription from RNA polymerase II promoter	Biological process	24517231
CRABP2	1382	cellular retinoic acid binding protein 2	retinal binding	Molecular function	-
NTRK1	4914	neurotrophic tyrosine kinase, receptor, type 1	positive regulation of programmed cell death	Biological process	-
SEMA4D	10507	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	regulation of cell projection organization	Biological process	20877282
KLK6	5653	kallikrein-related peptidase 6	collagen catabolic process	Biological process	12878203
NDFIP1	80762	Nedd4 family interacting protein 1	extracellular region	Cellular component	-
RCN2	5955	reticulocalbin 2, EF-hand calcium binding domain	protein binding	Molecular function	20562859
FLNA	2316	filamin A, alpha	establishment of protein localization	Biological process	18322202
ARHGEF2	9181	Rho/Rac guanine nucleotide exchange factor (GEF) 2	Rho GTPase binding	Molecular function	9857026
VAV1	7409	vav 1 guanine nucleotide exchange factor	Fc-gamma receptor signaling pathway involved in phagocytosis	Biological process	-
DYNLL1	8655	dynein, light chain, LC8-type 1	mitochondrion	Cellular component	-
CCNT1	904	cyclin T1	nucleolus	Cellular component	16109376
CENPJ	55835	centromere protein J	microtubule	Cellular component	-
SNAPIN	23557	SNAP-associated protein	secretory granule	Cellular component	-
REEP1	65055	receptor accessory protein 1	regulation of intracellular transport	Biological process	-
EPHA4	2043	EPH receptor A4	protein binding	Molecular function	12775584
MTHFR	4524	methylenetetrahydrofolate reductase (NAD(P)H)	response to folic acid	Biological process	-
CD320	51293	CD320 molecule	regulation of cell growth	Biological process	10727470
SLBP	7884	stem-loop binding protein	transcription from RNA polymerase II promoter	Biological process	-
OR6K6	128371	olfactory receptor, family 6, subfamily K, member 6	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
POLD3	10714	polymerase (DNA-directed), delta 3, accessory subunit	DNA-directed DNA polymerase activity	Molecular function	10219083
MPST	4357	mercaptopyruvate sulfurtransferase	cell junction	Cellular component	-
FUT5	2527	fucosyltransferase 5 (alpha (1,3) fucosyltransferase)	carbohydrate metabolic process	Biological process	1339443
FDPS	2224	farnesyl diphosphate synthase	cytosol	Cellular component	-
HHEX	3087	hematopoietically expressed homeobox	hepatic duct development	Biological process	-
AASS	10157	aminoadipate-semialdehyde synthase	cellular nitrogen compound metabolic process	Biological process	-
AKAP3	10566	A kinase (PRKA) anchor protein 3	movement of cell or subcellular component	Biological process	10319321
TRAC	28755	T cell receptor alpha constant	integral component of membrane	Cellular component	-
SSX7	280658	synovial sarcoma, X breakpoint 7	nucleic acid binding	Molecular function	-
UBXN6	80700	UBX domain protein 6	nucleolus	Cellular component	-
RECK	8434	reversion-inducing-cysteine-rich protein with kazal motifs	protein binding	Molecular function	21255571
BAG4	9530	BCL2-associated athanogene 4	plasma membrane	Cellular component	21712384
LYN	4067	LYN proto-oncogene, Src family tyrosine kinase	regulation of cytokine production	Biological process	-
NDEL1	81565	nudE neurodevelopment protein 1-like 1	establishment of mitotic spindle orientation	Biological process	-
POLR3C	10623	polymerase (RNA) III (DNA directed) polypeptide C (62kD)	gene expression	Biological process	-
MAP2K7	5609	mitogen-activated protein kinase kinase 7	toll-like receptor 9 signaling pathway	Biological process	-
ZNF593	51042	zinc finger protein 593	transcription, DNA-templated	Biological process	-
NOG	9241	noggin	prostatic bud formation	Biological process	-
RILP	83547	Rab interacting lysosomal protein	protein complex	Cellular component	-
TBX2	6909	T-box 2	atrioventricular canal development	Biological process	-
ULK2	9706	unc-51 like autophagy activating kinase 2	regulation of autophagy	Biological process	18936157
AGPAT1	10554	1-acylglycerol-3-phosphate O-acyltransferase 1	CDP-diacylglycerol biosynthetic process	Biological process	-
SHH	6469	sonic hedgehog	positive regulation of neuroblast proliferation	Biological process	-
ANKFY1	51479	ankyrin repeat and FYVE domain containing 1	positive regulation of pinocytosis	Biological process	15328530
THEG	51298	theg spermatid protein	multicellular organismal development	Biological process	-
TCTN2	79867	tectonic family member 2	integral component of membrane	Cellular component	-
CNNM1	26507	cyclin and CBS domain divalent metal cation transport mediator 1	integral component of membrane	Cellular component	-
CDC42	998	cell division cycle 42	submandibular salivary gland formation	Biological process	-
SNX32	254122	sorting nexin 32	extrinsic component of membrane	Cellular component	-
LAMC2	3918	laminin, gamma 2	epidermis development	Biological process	8012394
DAZAP1	26528	DAZ associated protein 1	poly(A) RNA binding	Molecular function	22658674
ASH1L	55870	ash1 (absent, small, or homeotic)-like (Drosophila)	extracellular exosome	Cellular component	23376485
AJUBA	84962	ajuba LIM protein	G2/M transition of mitotic cell cycle	Biological process	-
MMADHC	27249	methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria	cobalamin metabolic process	Biological process	-
PLD2	5338	phospholipase D2	phosphatidylinositol binding	Molecular function	-
HFE2	148738	hemochromatosis type 2 (juvenile)	glycoprotein binding	Molecular function	22728873
PTGDR	5729	prostaglandin D2 receptor (DP)	protein binding	Molecular function	20959461
HOXA10	3206	homeobox A10	protein binding	Molecular function	18692240
PGLYRP3	114771	peptidoglycan recognition protein 3	defense response to Gram-positive bacterium	Biological process	11461926
INVS	27130	inversin	membrane	Cellular component	-
KCNE3	10008	potassium channel, voltage gated subfamily E regulatory beta subunit 3	neuronal cell body membrane	Cellular component	12954870
ALX4	60529	ALX homeobox 4	embryonic digit morphogenesis	Biological process	-
AEN	64782	apoptosis enhancing nuclease	nucleolus	Cellular component	-
PPP2R3A	5523	protein phosphatase 2, regulatory subunit B'', alpha	negative regulation of canonical Wnt signaling pathway	Biological process	15687260
NUMB	8650	numb homolog (Drosophila)	extrinsic component of plasma membrane	Cellular component	-
ARID4B	51742	AT rich interactive domain 4B (RBP1-like)	cytoplasm	Cellular component	-
SF3A1	10291	splicing factor 3a, subunit 1, 120kDa	U2-type prespliceosome	Cellular component	-
BAG3	9531	BCL2-associated athanogene 3	spinal cord development	Biological process	-
ESR2	2100	estrogen receptor 2 (ER beta)	positive regulation of sequence-specific DNA binding transcription factor activity	Biological process	10681512
CTSG	1511	cathepsin G	peptidase activity	Molecular function	11907569
IDO2	169355	indoleamine 2,3-dioxygenase 2	small molecule metabolic process	Biological process	-
ITPR1	3708	inositol 1,4,5-trisphosphate receptor, type 1	release of sequestered calcium ion into cytosol	Biological process	-
PCSK9	255738	proprotein convertase subtilisin/kexin type 9	cellular response to insulin stimulus	Biological process	12552133
IFT122	55764	intraflagellar transport 122	camera-type eye morphogenesis	Biological process	-
CER1	9350	cerberus 1, DAN family BMP antagonist	bone mineralization	Biological process	19113921
PMAIP1	5366	phorbol-12-myristate-13-acetate-induced protein 1	nucleus	Cellular component	12879012
PDPK1	5170	3-phosphoinositide dependent protein kinase 1	extrinsic apoptotic signaling pathway	Biological process	16207722
ST6GALNAC2	10610	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2	cellular protein metabolic process	Biological process	-
AK6	102157402	adenylate kinase 6	ATP binding	Molecular function	-
NTHL1	4913	nth endonuclease III-like 1 (E. coli)	DNA N-glycosylase activity	Molecular function	10882850
ISG15	9636	ISG15 ubiquitin-like modifier	response to type I interferon	Biological process	22859821
NTRK1	4914	neurotrophic tyrosine kinase, receptor, type 1	dendrite	Cellular component	-
ARFGAP3	26286	ADP-ribosylation factor GTPase activating protein 3	protein transporter activity	Molecular function	11172815
RAMP3	10268	receptor (G protein-coupled) activity modifying protein 3	receptor complex	Cellular component	15613468
GTF2IRD2B	389524	GTF2I repeat domain containing 2B	transcription, DNA-templated	Biological process	-
PKNOX1	5316	PBX/knotted 1 homeobox 1	transcription from RNA polymerase II promoter	Biological process	-
CA12	771	carbonic anhydrase XII	chloride ion homeostasis	Biological process	21035102
ACTN4	81	actinin, alpha 4	extracellular region	Cellular component	-
GSN	2934	gelsolin	hepatocyte apoptotic process	Biological process	22952982
PRIM1	5557	primase, DNA, polypeptide 1 (49kDa)	telomere maintenance via semi-conservative replication	Biological process	-
CLCF1	23529	cardiotrophin-like cytokine factor 1	receptor binding	Molecular function	15272019
MS4A2	2206	membrane-spanning 4-domains, subfamily A, member 2	positive regulation of mast cell degranulation	Biological process	-
NEUROD6	63974	neuronal differentiation 6	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
CRHBP	1393	corticotropin releasing hormone binding protein	hormone metabolic process	Biological process	-
IL17RD	54756	interleukin 17 receptor D	integral component of plasma membrane	Cellular component	-
CACNG4	27092	calcium channel, voltage-dependent, gamma subunit 4	plasma membrane	Cellular component	-
DPM1	8813	dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit	post-translational protein modification	Biological process	-
PNOC	5368	prepronociceptin	neuropeptide hormone activity	Molecular function	10419552
EXOC8	149371	exocyst complex component 8	cytoplasm	Cellular component	-
CD58	965	CD58 molecule	single organismal cell-cell adhesion	Biological process	7544493
SOD1	6647	superoxide dismutase 1, soluble	retina homeostasis	Biological process	-
EPB41L3	23136	erythrocyte membrane protein band 4.1-like 3	actin binding	Molecular function	-
TEKT4	150483	tektin 4	cell projection organization	Biological process	-
OR51E2	81285	olfactory receptor, family 51, subfamily E, member 2	G-protein coupled receptor activity	Molecular function	-
MAPKAPK3	7867	mitogen-activated protein kinase-activated protein kinase 3	toll-like receptor signaling pathway	Biological process	-
RBL1	5933	retinoblastoma-like 1	gene expression	Biological process	-
ZBTB8A	653121	zinc finger and BTB domain containing 8A	transcription, DNA-templated	Biological process	-
ZNF350	59348	zinc finger protein 350	metal ion binding	Molecular function	-
SEC24B	10427	SEC24 family member B	COPII vesicle coat	Cellular component	-
TIMM10B	26515	translocase of inner mitochondrial membrane 10 homolog B (yeast)	protein targeting to mitochondrion	Biological process	-
ATP7A	538	ATPase, Cu++ transporting, alpha polypeptide	basolateral plasma membrane	Cellular component	16397091
KRT1	3848	keratin 1, type II	keratin filament	Cellular component	-
SERPINB11	89778	serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene)	extracellular space	Cellular component	-
PSMD4	5710	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
GNGT2	2793	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2	synaptic transmission	Biological process	-
RPS19	6223	ribosomal protein S19	viral transcription	Biological process	-
MZF1	7593	myeloid zinc finger 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	7579328
RYR2	6262	ryanodine receptor 2 (cardiac)	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	Biological process	-
PHLDA2	7262	pleckstrin homology-like domain, family A, member 2	organ morphogenesis	Biological process	-
AKT2	208	v-akt murine thymoma viral oncogene homolog 2	positive regulation of glucose metabolic process	Biological process	16814735
FSTL3	10272	follistatin-like 3 (secreted glycoprotein)	lung development	Biological process	-
DDX46	9879	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46	poly(A) RNA binding	Molecular function	22681889
TFDP2	7029	transcription factor Dp-2 (E2F dimerization partner 2)	transcription initiation from RNA polymerase II promoter	Biological process	-
PTPRZ1	5803	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	protein tyrosine phosphatase activity	Molecular function	-
TSEN2	80746	TSEN2 tRNA splicing endonuclease subunit	tRNA-intron endonuclease complex	Cellular component	-
POLR3K	51728	polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa	positive regulation of type I interferon production	Biological process	-
SCN2A	6326	sodium channel, voltage gated, type II alpha subunit	axon	Cellular component	16652168
USH2A	7399	Usher syndrome 2A (autosomal recessive, mild)	apical plasma membrane	Cellular component	-
SCNN1A	6337	sodium channel, non voltage gated 1 alpha subunit	WW domain binding	Molecular function	10642508
MAML3	55534	mastermind-like 3 (Drosophila)	nucleoplasm	Cellular component	-
AKAP7	9465	A kinase (PRKA) anchor protein 7	regulation of membrane repolarization	Biological process	11299204
STX16	8675	syntaxin 16	focal adhesion	Cellular component	21423176
CXCR3	2833	chemokine (C-X-C motif) receptor 3	inflammatory response	Biological process	-
UTP6	55813	UTP6, small subunit (SSU) processome component, homolog (yeast)	nucleolus	Cellular component	-
FAM189B	10712	family with sequence similarity 189, member B	integral component of membrane	Cellular component	-
ITGAV	3685	integrin, alpha V	negative regulation of low-density lipoprotein particle receptor biosynthetic process	Biological process	15215180
NNT	23530	nicotinamide nucleotide transhydrogenase	hydrogen ion transmembrane transport	Biological process	9524818
SCNN1A	6337	sodium channel, non voltage gated 1 alpha subunit	sodium ion transmembrane transport	Biological process	24124190
AFAP1L2	84632	actin filament associated protein 1-like 2	positive regulation of epidermal growth factor receptor signaling pathway	Biological process	17412687
ABHD8	79575	abhydrolase domain containing 8	metabolic process	Biological process	-
CD2	914	CD2 molecule	plasma membrane	Cellular component	-
GPC1	2817	glypican 1	positive regulation of skeletal muscle cell differentiation	Biological process	-
MCC	4163	mutated in colorectal cancers	cytoplasm	Cellular component	-
DCAKD	79877	dephospho-CoA kinase domain containing	dephospho-CoA kinase activity	Molecular function	-
CTSD	1509	cathepsin D	extracellular space	Cellular component	22261194
SF3A1	10291	splicing factor 3a, subunit 1, 120kDa	RNA binding	Molecular function	10882114
IGHV3-23	28442	immunoglobulin heavy variable 3-23	antigen binding	Molecular function	6450418
NLRC3	197358	NLR family, CARD domain containing 3	negative regulation of tumor necrosis factor production	Biological process	22863753
MBD2	8932	methyl-CpG binding domain protein 2	maternal behavior	Biological process	-
KLK5	25818	kallikrein-related peptidase 5	proteolysis	Biological process	-
PAF1	54623	Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)	positive regulation of histone methylation	Biological process	22046413
RPS29	6235	ribosomal protein S29	extracellular exosome	Cellular component	20458337
ZNF205	7755	zinc finger protein 205	nucleus	Cellular component	-
C2CD4B	388125	C2 calcium-dependent domain containing 4B	synaptic vesicle exocytosis	Biological process	-
MYC	4609	v-myc avian myelocytomatosis viral oncogene homolog	response to growth factor	Biological process	18987311
FLRT2	23768	fibronectin leucine rich transmembrane protein 2	intracellular signal transduction	Biological process	10644439
MEF2C	4208	myocyte enhancer factor 2C	regulation of synaptic transmission, glutamatergic	Biological process	-
PVRL1	5818	poliovirus receptor-related 1 (herpesvirus entry mediator C)	virus receptor activity	Molecular function	-
TNFRSF8	943	tumor necrosis factor receptor superfamily, member 8	plasma membrane	Cellular component	-
EPX	8288	eosinophil peroxidase	metal ion binding	Molecular function	-
SPAG6	9576	sperm associated antigen 6	axoneme	Cellular component	10493827
CAPG	822	capping protein (actin filament), gelsolin-like	nucleolus	Cellular component	18938132
HHAT	55733	hedgehog acyltransferase	GTP binding	Molecular function	-
MSC	9242	musculin	sequence-specific DNA binding transcription factor activity	Molecular function	9584154
F9	2158	coagulation factor IX	extracellular space	Cellular component	2592373
USF2	7392	upstream transcription factor 2, c-fos interacting	double-stranded DNA binding	Molecular function	-
CREB3L1	90993	cAMP responsive element binding protein 3-like 1	transcription, DNA-templated	Biological process	-
ATP13A4	84239	ATPase type 13A4	metabolic process	Biological process	-
RFTN1	23180	raftlin, lipid raft linker 1	membrane raft	Cellular component	12805216
HRAS	3265	Harvey rat sarcoma viral oncogene homolog	cell proliferation	Biological process	-
HSP90AB1	3326	heat shock protein 90kDa alpha (cytosolic), class B member 1	double-stranded RNA binding	Molecular function	21266579
WNT6	7475	wingless-type MMTV integration site family, member 6	cellular response to retinoic acid	Biological process	-
TRAPPC13	80006	trafficking protein particle complex 13	protein binding	Molecular function	21453443
ACVRL1	94	activin A receptor type II-like 1	negative regulation of cell migration	Biological process	12453878
REG3A	5068	regenerating islet-derived 3 alpha	cytoplasm	Cellular component	8997243
CFI	3426	complement factor I	scavenger receptor activity	Molecular function	-
STXBP6	29091	syntaxin binding protein 6 (amisyn)	phosphatidylinositol-4,5-bisphosphate binding	Molecular function	-
MVB12B	89853	multivesicular body subunit 12B	nucleus	Cellular component	22232651
EIF3M	10480	eukaryotic translation initiation factor 3, subunit M	eukaryotic translation initiation factor 3 complex, eIF3m	Cellular component	-
DVL2	1856	dishevelled segment polarity protein 2	positive regulation of protein tyrosine kinase activity	Biological process	-
ARSG	22901	arylsulfatase G	cellular protein metabolic process	Biological process	-
ILF2	3608	interleukin enhancer binding factor 2	ribonucleoprotein complex	Cellular component	17289661
INSR	3643	insulin receptor	caveola	Cellular component	15182363
CERK	64781	ceramide kinase	ceramide kinase activity	Molecular function	11956206
TERF2	7014	telomeric repeat binding factor 2	cytoplasm	Cellular component	-
ACACA	31	acetyl-CoA carboxylase alpha	extracellular exosome	Cellular component	23376485
MEF2C	4208	myocyte enhancer factor 2C	MyD88-dependent toll-like receptor signaling pathway	Biological process	-
ALCAM	214	activated leukocyte cell adhesion molecule	protein binding	Molecular function	24945728
NCKAP1L	3071	NCK-associated protein 1-like	chemotaxis	Biological process	16417406
PAH	5053	phenylalanine hydroxylase	L-phenylalanine catabolic process	Biological process	-
CAB39	51719	calcium binding protein 39	protein heterooligomerization	Biological process	-
CBX8	57332	chromobox homolog 8	protein binding	Molecular function	16169070
PURA	5813	purine-rich element binding protein A	nervous system development	Biological process	-
ENPP1	5167	ectonucleotide pyrophosphatase/phosphodiesterase 1	negative regulation of glycogen biosynthetic process	Biological process	11289049
SYT4	6860	synaptotagmin IV	calcium ion-dependent exocytosis of neurotransmitter	Biological process	-
MTMR2	8898	myotubularin related protein 2	myelin assembly	Biological process	-
TNC	3371	tenascin C	interstitial matrix	Cellular component	-
SSR3	6747	signal sequence receptor, gamma (translocon-associated protein gamma)	SRP-dependent cotranslational protein targeting to membrane	Biological process	-
KDR	3791	kinase insert domain receptor	cell fate commitment	Biological process	-
RFX3	5991	regulatory factor X, 3 (influences HLA class II expression)	cilium-dependent cell motility	Biological process	-
OR6C1	390321	olfactory receptor, family 6, subfamily C, member 1	plasma membrane	Cellular component	-
POLD4	57804	polymerase (DNA-directed), delta 4, accessory subunit	nucleotide-excision repair, DNA gap filling	Biological process	-
KNG1	3827	kininogen 1	zinc ion binding	Molecular function	12911595
P2RX7	5027	purinergic receptor P2X, ligand gated ion channel, 7	ceramide biosynthetic process	Biological process	-
CTNNA3	29119	catenin (cadherin-associated protein), alpha 3	single organismal cell-cell adhesion	Biological process	11590244
RAB28	9364	RAB28, member RAS oncogene family	GTP binding	Molecular function	19026641
DNASE2B	58511	deoxyribonuclease II beta	deoxyribonuclease II activity	Molecular function	-
RNF19A	25897	ring finger protein 19A, RBR E3 ubiquitin protein ligase	cytoplasm	Cellular component	-
CDK5RAP1	51654	CDK5 regulatory subunit associated protein 1	brain development	Biological process	10915792
CALM1	801	calmodulin 1 (phosphorylase kinase, delta)	protein phosphatase activator activity	Molecular function	8631777
BID	637	BH3 interacting domain death agonist	cytosol	Cellular component	-
MIS12	79003	MIS12 kinetochore complex component	mitotic cell cycle	Biological process	-
SMAD4	4089	SMAD family member 4	somite rostral/caudal axis specification	Biological process	-
NKX2-5	1482	NK2 homeobox 5	cardiac muscle contraction	Biological process	-
FOSL1	8061	FOS-like antigen 1	neuron projection	Cellular component	-
TH	7054	tyrosine hydroxylase	cytosol	Cellular component	-
RAD51	5888	RAD51 recombinase	ATP binding	Molecular function	16428451
CT83	203413	cancer/testis antigen 83	nucleus	Cellular component	21630459
DFNB31	25861	deafness, autosomal recessive 31	inner ear receptor stereocilium organization	Biological process	-
ORC3	23595	origin recognition complex, subunit 3	DNA replication origin binding	Molecular function	9829972
ADAM2	2515	ADAM metallopeptidase domain 2	single fertilization	Biological process	-
RTN4	57142	reticulon 4	endomembrane system	Cellular component	-
HPN	3249	hepsin	cell surface	Cellular component	16908524
ADAR	103	adenosine deaminase, RNA-specific	mRNA modification	Biological process	-
RALGDS	5900	ral guanine nucleotide dissociation stimulator	cytosol	Cellular component	-
DSP	1832	desmoplakin	wound healing	Biological process	-
CEBPA	1050	CCAAT/enhancer binding protein (C/EBP), alpha	transcription from RNA polymerase I promoter	Biological process	20075868
HVCN1	84329	hydrogen voltage gated channel 1	single fertilization	Biological process	-
STAT3	6774	signal transducer and activator of transcription 3 (acute-phase response factor)	transcription factor binding	Molecular function	15664994
EIF3G	8666	eukaryotic translation initiation factor 3, subunit G	cellular protein metabolic process	Biological process	-
GTF3C4	9329	general transcription factor IIIC, polypeptide 4, 90kDa	transcription from RNA polymerase III promoter	Biological process	-
CBS	875	cystathionine-beta-synthase	protein homodimerization activity	Molecular function	11483494
FBN3	84467	fibrillin 3	proteinaceous extracellular matrix	Cellular component	-
SNAI2	6591	snail family zinc finger 2	canonical Wnt signaling pathway	Biological process	20128911
PDGFB	5155	platelet-derived growth factor beta polypeptide	platelet-derived growth factor binding	Molecular function	7073684
KLF13	51621	Kruppel-like factor 13	DNA binding	Molecular function	-
DDX39A	10212	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A	mRNA splicing, via spliceosome	Biological process	15047853
OLFM2	93145	olfactomedin 2	synapse	Cellular component	-
VRK3	51231	vaccinia related kinase 3	regulation of cell shape	Biological process	-
EPGN	255324	epithelial mitogen	positive regulation of epithelial cell proliferation	Biological process	-
PLAT	5327	plasminogen activator, tissue	serine-type endopeptidase activity	Molecular function	-
ILF3	3609	interleukin enhancer binding factor 3, 90kDa	RNA binding	Molecular function	10400669
CLCN5	1184	chloride channel, voltage-sensitive 5	apical part of cell	Cellular component	14675051
TCEB1	6921	transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)	nucleoplasm	Cellular component	-
S100P	6286	S100 calcium binding protein P	microvillus membrane	Cellular component	-
CD2	914	CD2 molecule	protein homodimerization activity	Molecular function	-
PRDX5	25824	peroxiredoxin 5	reactive nitrogen species metabolic process	Biological process	15280035
GNGT1	2792	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	synaptic transmission	Biological process	-
PELI2	57161	pellino E3 ubiquitin protein ligase family member 2	toll-like receptor 4 signaling pathway	Biological process	-
KAT8	84148	K(lysine) acetyltransferase 8	myeloid cell differentiation	Biological process	11742995
TGFBR1	7046	transforming growth factor, beta receptor 1	thymus development	Biological process	-
SLC11A1	6556	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1	response to bacterium	Biological process	7717395
DDR1	780	discoidin domain receptor tyrosine kinase 1	regulation of extracellular matrix disassembly	Biological process	12065315
GIP	2695	gastric inhibitory polypeptide	response to starvation	Biological process	-
KRT24	192666	keratin 24, type I	extracellular exosome	Cellular component	23533145
CSRP1	1465	cysteine and glycine-rich protein 1	focal adhesion	Cellular component	21423176
RAP2A	5911	RAP2A, member of RAS oncogene family	recycling endosome membrane	Cellular component	19061864
LRP8	7804	low density lipoprotein receptor-related protein 8, apolipoprotein e receptor	blood coagulation	Biological process	-
TRERF1	55809	transcriptional regulating factor 1	RNA polymerase II transcription cofactor activity	Molecular function	11349124
POLR2A	5430	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	piRNA metabolic process	Biological process	-
GAS6	2621	growth arrest-specific 6	leukocyte migration	Biological process	-
MFSD10	10227	major facilitator superfamily domain containing 10	tetracycline transport	Biological process	8353488
PPOX	5498	protoporphyrinogen oxidase	porphyrin-containing compound metabolic process	Biological process	-
SLC9B2	133308	solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2	solute:proton antiporter activity	Molecular function	-
CYP2C19	1557	cytochrome P450, family 2, subfamily C, polypeptide 19	oxygen binding	Molecular function	3442670
CAMKK2	10645	calcium/calmodulin-dependent protein kinase kinase 2, beta	protein tyrosine kinase activity	Molecular function	11395482
SLC26A7	115111	solute carrier family 26 (anion exchanger), member 7	anion transport	Biological process	11834742
OR5B12	390191	olfactory receptor, family 5, subfamily B, member 12	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
TWISTNB	221830	TWIST neighbor	DNA-directed RNA polymerase I complex	Cellular component	-
EPHX2	2053	epoxide hydrolase 2, cytoplasmic	stilbene catabolic process	Biological process	8342951
MRPL23	6150	mitochondrial ribosomal protein L23	mitochondrial translational termination	Biological process	-
SERINC3	10955	serine incorporator 3	L-serine transmembrane transporter activity	Molecular function	-
SETMAR	6419	SET domain and mariner transposase fusion gene	cell proliferation	Biological process	20457750
AGK	55750	acylglycerol kinase	ATP binding	Molecular function	-
NGFR	4804	nerve growth factor receptor	circadian regulation of gene expression	Biological process	-
OSBPL11	114885	oxysterol binding protein-like 11	positive regulation of sequestering of triglyceride	Biological process	23028956
ZDHHC16	84287	zinc finger, DHHC-type containing 16	integral component of membrane	Cellular component	-
PPP1CB	5500	protein phosphatase 1, catalytic subunit, beta isozyme	G2/M transition of mitotic cell cycle	Biological process	-
TUBGCP4	27229	tubulin, gamma complex associated protein 4	gamma-tubulin ring complex	Cellular component	10562286
PAK1	5058	p21 protein (Cdc42/Rac)-activated kinase 1	positive regulation of JUN kinase activity	Biological process	8805275
TNRC18	84629	trinucleotide repeat containing 18	chromatin silencing	Biological process	-
AHCY	191	adenosylhomocysteinase	methylation	Biological process	-
AP1M1	8907	adaptor-related protein complex 1, mu 1 subunit	extracellular exosome	Cellular component	19056867
ABCG5	64240	ATP-binding cassette, sub-family G (WHITE), member 5	apical plasma membrane	Cellular component	14504269
ACSL1	2180	acyl-CoA synthetase long-chain family member 1	integral component of membrane	Cellular component	-
PTPRC	5788	protein tyrosine phosphatase, receptor type, C	protein dephosphorylation	Biological process	-
RNF14	9604	ring finger protein 14	transcription, DNA-templated	Biological process	-
CASP8	841	caspase 8, apoptosis-related cysteine peptidase	microtubule organizing center	Cellular component	-
SH3D19	152503	SH3 domain containing 19	protein binding	Molecular function	15280379
APH1A	51107	APH1A gamma secretase subunit	positive regulation of catalytic activity	Biological process	15274632
HDAC6	10013	histone deacetylase 6	histone H3-K9 deacetylation	Biological process	-
NUP54	53371	nucleoporin 54kDa	mRNA transport	Biological process	-
SEMA3E	9723	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E	regulation of cell shape	Biological process	-
CEP131	22994	centrosomal protein 131kDa	spermatogenesis	Biological process	-
CLVS1	157807	clavesin 1	early endosome membrane	Cellular component	-
CD24	100133941	CD24 molecule	cholesterol homeostasis	Biological process	16390867
GPR12	2835	G protein-coupled receptor 12	G-protein coupled receptor signaling pathway	Biological process	-
GYG1	2992	glycogenin 1	glucose metabolic process	Biological process	-
MAP7D3	79649	MAP7 domain containing 3	nucleoplasm	Cellular component	-
EPHX2	2053	epoxide hydrolase 2, cytoplasmic	response to toxic substance	Biological process	10862610
TNK1	8711	tyrosine kinase, non-receptor, 1	protein binding	Molecular function	10873601
ITGA5	3678	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	vascular endothelial growth factor receptor 2 binding	Molecular function	19267251
PSMB5	5693	proteasome (prosome, macropain) subunit, beta type, 5	proteasome core complex	Cellular component	-
SLC1A1	6505	solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1	extracellular exosome	Cellular component	19056867
WNT10A	80326	wingless-type MMTV integration site family, member 10A	hair follicle morphogenesis	Biological process	20163410
FDPS	2224	farnesyl diphosphate synthase	nucleoplasm	Cellular component	-
TADA3	10474	transcriptional adaptor 3	intracellular estrogen receptor signaling pathway	Biological process	20413580
CALB2	794	calbindin 2	cytoplasm	Cellular component	-
SYNGR1	9145	synaptogyrin 1	protein binding	Molecular function	25416956
ZNF350	59348	zinc finger protein 350	negative regulation of transcription, DNA-templated	Biological process	11090615
ZNF90	7643	zinc finger protein 90	nucleus	Cellular component	-
PDGFRB	5159	platelet-derived growth factor receptor, beta polypeptide	positive regulation of calcium ion import	Biological process	-
TCIRG1	10312	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3	positive regulation of cell proliferation	Biological process	9806637
MTMR4	9110	myotubularin related protein 4	protein binding	Molecular function	20061380
GAGE2A	729447	G antigen 2A	molecular_function	Molecular function	-
PARP2	10038	poly (ADP-ribose) polymerase 2	base-excision repair	Biological process	-
RARB	5915	retinoic acid receptor, beta	zinc ion binding	Molecular function	-
CLN3	1201	ceroid-lipofuscinosis, neuronal 3	late endosome	Cellular component	-
INHBA	3624	inhibin, beta A	positive regulation of erythrocyte differentiation	Biological process	9032295
CCK	885	cholecystokinin	neuron migration	Biological process	15152034
MAOA	4128	monoamine oxidase A	cellular biogenic amine metabolic process	Biological process	8211186
CHPT1	56994	choline phosphotransferase 1	small molecule metabolic process	Biological process	-
FCGR1B	2210	Fc fragment of IgG, high affinity Ib, receptor (CD64)	antigen processing and presentation of peptide antigen via MHC class I	Biological process	-
RIPK3	11035	receptor-interacting serine-threonine kinase 3	regulation of interferon-gamma production	Biological process	-
PODXL	5420	podocalyxin-like	extracellular space	Cellular component	16502470
LIG1	3978	ligase I, DNA, ATP-dependent	telomere maintenance via semi-conservative replication	Biological process	-
RAPGEF2	9693	Rap guanine nucleotide exchange factor (GEF) 2	cAMP-mediated signaling	Biological process	10934204
AHCTF1	25909	AT hook containing transcription factor 1	regulation of transcription, DNA-templated	Biological process	-
CYR61	3491	cysteine-rich, angiogenic inducer, 61	wound healing, spreading of cells	Biological process	20675382
RABGGTA	5875	Rab geranylgeranyltransferase, alpha subunit	Rab-protein geranylgeranyltransferase complex	Cellular component	-
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	lens morphogenesis in camera-type eye	Biological process	-
BCL11A	53335	B-cell CLL/lymphoma 11A (zinc finger protein)	nucleus	Cellular component	19616629
DIAPH2	1730	diaphanous-related formin 2	receptor binding	Molecular function	9497258
NRG2	9542	neuregulin 2	neurotrophin TRK receptor signaling pathway	Biological process	-
F2RL1	2150	coagulation factor II (thrombin) receptor-like 1	positive regulation of cell migration	Biological process	-
CYBB	1536	cytochrome b-245, beta polypeptide	ion transport	Biological process	-
TXN	7295	thioredoxin	response to reactive oxygen species	Biological process	-
S100A6	6277	S100 calcium binding protein A6	cytosol	Cellular component	19724273
CHCHD3	54927	coiled-coil-helix-coiled-coil-helix domain containing 3	negative regulation of transcription from RNA polymerase II promoter	Biological process	22567091
OR5AK2	390181	olfactory receptor, family 5, subfamily AK, member 2	G-protein coupled receptor activity	Molecular function	-
PDCD2	5134	programmed cell death 2	cytoplasm	Cellular component	-
SERPINH1	871	serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)	extracellular space	Cellular component	-
HAP1	9001	huntingtin-associated protein 1	regulation of organelle transport along microtubule	Biological process	-
DICER1	23405	dicer 1, ribonuclease type III	angiogenesis	Biological process	-
LAYN	143903	layilin	hyaluronic acid binding	Molecular function	11294894
CDKN1B	1027	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	negative regulation of cell proliferation	Biological process	19838216
PLSCR1	5359	phospholipid scramblase 1	phosphatidylserine biosynthetic process	Biological process	-
TNFSF15	9966	tumor necrosis factor (ligand) superfamily, member 15	activation of NF-kappaB-inducing kinase activity	Biological process	11911831
IGF1R	3480	insulin-like growth factor 1 receptor	insulin-like growth factor receptor signaling pathway	Biological process	7679099
KCNJ10	3766	potassium channel, inwardly rectifying subfamily J, member 10	response to glucocorticoid	Biological process	-
CPA2	1358	carboxypeptidase A2 (pancreatic)	zinc ion binding	Molecular function	2920728
DBP	1628	D site of albumin promoter (albumin D-box) binding protein	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	20093779
EIF1	10209	eukaryotic translation initiation factor 1	regulation of translational initiation	Biological process	22156057
RNFT2	84900	ring finger protein, transmembrane 2	zinc ion binding	Molecular function	-
IGHE	3497	immunoglobulin heavy constant epsilon	extracellular region	Cellular component	-
SERPINB2	5055	serpin peptidase inhibitor, clade B (ovalbumin), member 2	extracellular region	Cellular component	-
THRAP3	9967	thyroid hormone receptor associated protein 3	mRNA processing	Biological process	-
RIPK2	8767	receptor-interacting serine-threonine kinase 2	protein serine/threonine kinase activity	Molecular function	-
BMP2	650	bone morphogenetic protein 2	cellular response to BMP stimulus	Biological process	20843790
RBM42	79171	RNA binding motif protein 42	poly(A) RNA binding	Molecular function	22658674
GGN	199720	gametogenetin	protein localization	Biological process	-
CYP2B6	1555	cytochrome P450, family 2, subfamily B, polypeptide 6	monooxygenase activity	Molecular function	19651758
FGD1	2245	FYVE, RhoGEF and PH domain containing 1	small GTPase mediated signal transduction	Biological process	-
NT5C3A	51251	5'-nucleotidase, cytosolic IIIA	nucleotide binding	Molecular function	-
SNIP1	79753	Smad nuclear interacting protein 1	production of miRNAs involved in gene silencing by miRNA	Biological process	18632581
SCYL2	55681	SCY1-like 2 (S. cerevisiae)	positive regulation of clathrin-mediated endocytosis	Biological process	19643732
GPC4	2239	glypican 4	small molecule metabolic process	Biological process	-
SGK1	6446	serum/glucocorticoid regulated kinase 1	protein phosphorylation	Biological process	-
HAND2	9464	heart and neural crest derivatives expressed 2	apoptotic process involved in heart morphogenesis	Biological process	-
PIGN	23556	phosphatidylinositol glycan anchor biosynthesis, class N	preassembly of GPI anchor in ER membrane	Biological process	-
NUP85	79902	nucleoporin 85kDa	membrane	Cellular component	19946888
PTPN22	26191	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	T cell differentiation	Biological process	-
HIST1H4C	8364	histone cluster 1, H4c	mitotic cell cycle	Biological process	-
NOTCH1	4851	notch 1	positive regulation of cell proliferation	Biological process	20613903
MAFB	9935	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B	transcription factor binding	Molecular function	10698492
TDGF1	6997	teratocarcinoma-derived growth factor 1	Golgi apparatus	Cellular component	-
PSME4	23198	proteasome (prosome, macropain) activator subunit 4	multicellular organismal development	Biological process	-
LTF	4057	lactotransferrin	retina homeostasis	Biological process	23580065
OR5B2	390190	olfactory receptor, family 5, subfamily B, member 2	G-protein coupled receptor signaling pathway	Biological process	-
CASP8	841	caspase 8, apoptosis-related cysteine peptidase	protein complex binding	Molecular function	-
BMP3	651	bone morphogenetic protein 3	positive regulation of pathway-restricted SMAD protein phosphorylation	Biological process	-
COL6A6	131873	collagen, type VI, alpha 6	cell adhesion	Biological process	-
ATP5I	521	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E	hydrogen ion transmembrane transporter activity	Molecular function	-
MAEA	10296	macrophage erythroblast attacher	cytoskeleton	Cellular component	16510120
ACVR1B	91	activin A receptor, type IB	activin receptor activity, type I	Molecular function	8622651
MYO6	4646	myosin VI	nucleus	Cellular component	16507995
SMAD3	4088	SMAD family member 3	protein stabilization	Biological process	20097766
LAMP1	3916	lysosomal-associated membrane protein 1	phagolysosome membrane	Cellular component	-
HSD17B10	3028	hydroxysteroid (17-beta) dehydrogenase 10	endoplasmic reticulum	Cellular component	-
A2M	2	alpha-2-macroglobulin	negative regulation of endopeptidase activity	Biological process	-
LAMA1	284217	laminin, alpha 1	extracellular matrix structural constituent	Molecular function	-
PGK1	5230	phosphoglycerate kinase 1	ATP binding	Molecular function	-
PSMC4	5704	proteasome (prosome, macropain) 26S subunit, ATPase, 4	positive regulation of canonical Wnt signaling pathway	Biological process	-
UGT1A8	54576	UDP glucuronosyltransferase 1 family, polypeptide A8	glucuronosyltransferase activity	Molecular function	20610558
EEF1A2	1917	eukaryotic translation elongation factor 1 alpha 2	translational elongation	Biological process	-
SUMF1	285362	sulfatase modifying factor 1	small molecule metabolic process	Biological process	-
ADAM18	8749	ADAM metallopeptidase domain 18	multicellular organismal development	Biological process	-
HTATSF1	27336	HIV-1 Tat specific factor 1	poly(A) RNA binding	Molecular function	22658674
LBR	3930	lamin B receptor	integral component of nuclear inner membrane	Cellular component	8157662
XPO1	7514	exportin 1	mRNA transport	Biological process	-
LDLRAP1	26119	low density lipoprotein receptor adaptor protein 1	cytoplasmic side of plasma membrane	Cellular component	14528014
SPEF2	79925	sperm flagellar 2	protein dimerization activity	Molecular function	-
SPRY2	10253	sprouty homolog 2 (Drosophila)	positive regulation of gene expression	Biological process	18070883
TRIM36	55521	tripartite motif containing 36	acrosomal vesicle	Cellular component	-
TRIM23	373	tripartite motif containing 23	small GTPase mediated signal transduction	Biological process	-
CHRNB1	1140	cholinergic receptor, nicotinic, beta 1 (muscle)	cell junction	Cellular component	-
WDFY4	57705	WDFY family member 4	extrinsic component of membrane	Cellular component	-
DSTN	11034	destrin (actin depolymerizing factor)	protein binding	Molecular function	16189514
CCL21	6366	chemokine (C-C motif) ligand 21	ruffle organization	Biological process	15569314
CISD1	55847	CDGSH iron sulfur domain 1	integral component of membrane	Cellular component	-
GCM2	9247	glial cells missing homolog 2 (Drosophila)	negative regulation of apoptotic process	Biological process	-
PDXK	8566	pyridoxal (pyridoxine, vitamin B6) kinase	sodium ion binding	Molecular function	17766369
TMPRSS2	7113	transmembrane protease, serine 2	serine-type peptidase activity	Molecular function	9325052
CASP2	835	caspase 2, apoptosis-related cysteine peptidase	protein domain specific binding	Molecular function	9044836
RPS6	6194	ribosomal protein S6	cytoplasmic ribonucleoprotein granule	Cellular component	15121898
GBP7	388646	guanylate binding protein 7	membrane	Cellular component	-
NPFFR1	64106	neuropeptide FF receptor 1	neuropeptide signaling pathway	Biological process	-
UTP15	84135	UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)	cell junction	Cellular component	-
GAPT	202309	GRB2-binding adaptor protein, transmembrane	integral component of membrane	Cellular component	-
POU5F1	5460	POU class 5 homeobox 1	regulation of asymmetric cell division	Biological process	-
HRC	3270	histidine rich calcium binding protein	sarcoplasmic reticulum lumen	Cellular component	11504710
L3MBTL1	26013	l(3)mbt-like 1 (Drosophila)	nucleoplasm	Cellular component	10445843
SYCP2	10388	synaptonemal complex protein 2	nucleus	Cellular component	10341103
KANK2	25959	KN motif and ankyrin repeat domains 2	negative regulation of G1/S transition of mitotic cell cycle	Biological process	17476305
CRTC3	64784	CREB regulated transcription coactivator 3	macrophage activation	Biological process	23033494
FASLG	356	Fas ligand (TNF superfamily, member 6)	programmed cell death	Biological process	-
RFC1	5981	replication factor C (activator 1) 1, 145kDa	DNA replication factor C complex	Cellular component	9488738
AMICA1	120425	adhesion molecule, interacts with CXADR antigen 1	gamma-delta T cell activation	Biological process	-
ABCC1	4363	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	extracellular exosome	Cellular component	20458337
OR4K2	390431	olfactory receptor, family 4, subfamily K, member 2	plasma membrane	Cellular component	-
ATF7IP	55729	activating transcription factor 7 interacting protein	protein binding	Molecular function	12665582
TANK	10010	TRAF family member-associated NFKB activator	toll-like receptor signaling pathway	Biological process	-
IL10	3586	interleukin 10	extracellular space	Cellular component	10443688
LTBR	4055	lymphotoxin beta receptor (TNFR superfamily, member 3)	ubiquitin protein ligase binding	Molecular function	11279055
GLT8D1	55830	glycosyltransferase 8 domain containing 1	transferase activity, transferring glycosyl groups	Molecular function	-
PHF8	23133	PHD finger protein 8	nucleoplasm	Cellular component	-
RIPK3	11035	receptor-interacting serine-threonine kinase 3	regulation of activation-induced cell death of T cells	Biological process	-
PECR	55825	peroxisomal trans-2-enoyl-CoA reductase	2,4-dienoyl-CoA reductase (NADPH) activity	Molecular function	11669066
PIK3CG	5294	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	positive regulation of cytosolic calcium ion concentration	Biological process	-
VEGFA	7422	vascular endothelial growth factor A	membrane	Cellular component	-
HSD17B4	3295	hydroxysteroid (17-beta) dehydrogenase 4	very long-chain fatty-acyl-CoA metabolic process	Biological process	9482850
PDX1	3651	pancreatic and duodenal homeobox 1	positive regulation of insulin secretion	Biological process	-
SERPINB2	5055	serpin peptidase inhibitor, clade B (ovalbumin), member 2	cytoplasm	Cellular component	-
IFIH1	64135	interferon induced with helicase C domain 1	ATP binding	Molecular function	-
SULT2B1	6820	sulfotransferase family, cytosolic, 2B, member 1	xenobiotic metabolic process	Biological process	-
ARHGAP17	55114	Rho GTPase activating protein 17	plasma membrane	Cellular component	-
HIST2H3D	653604	histone cluster 2, H3d	histone binding	Molecular function	25615412
PLCL1	5334	phospholipase C-like 1	gamma-aminobutyric acid signaling pathway	Biological process	-
SP2	6668	Sp2 transcription factor	DNA binding	Molecular function	-
TNMD	64102	tenomodulin	negative regulation of angiogenesis	Biological process	-
GALNT11	63917	polypeptide N-acetylgalactosaminyltransferase 11	metal ion binding	Molecular function	-
NOTCH1	4851	notch 1	plasma membrane	Cellular component	-
B9D1	27077	B9 protein domain 1	membrane	Cellular component	-
TEAD1	7003	TEA domain family member 1 (SV40 transcriptional enhancer factor)	cytoplasm	Cellular component	-
KCNMA1	3778	potassium channel, calcium activated large conductance subfamily M alpha, member 1	caveola	Cellular component	15703204
IFNA17	3451	interferon, alpha 17	extracellular region	Cellular component	-
RTN4	57142	reticulon 4	protein binding	Molecular function	11126360
PDHA1	5160	pyruvate dehydrogenase (lipoamide) alpha 1	mitochondrion	Cellular component	20833797
GSTP1	2950	glutathione S-transferase pi 1	negative regulation of extrinsic apoptotic signaling pathway	Biological process	16636664
EMG1	10436	EMG1 N1-specific pseudouridine methyltransferase	rRNA (pseudouridine) methyltransferase activity	Molecular function	20047967
IFNG	3458	interferon, gamma	positive regulation of nitric oxide biosynthetic process	Biological process	8383325
NBPF6	653149	neuroblastoma breakpoint family, member 6	cytoplasm	Cellular component	-
DHCR24	1718	24-dehydrocholesterol reductase	regulation of neuron death	Biological process	16407971
FTO	79068	fat mass and obesity associated	DNA dealkylation involved in DNA repair	Biological process	18775698
RHCG	51458	Rh family, C glycoprotein	cytoplasmic vesicle	Cellular component	-
PDPK1	5170	3-phosphoinositide dependent protein kinase 1	insulin receptor signaling pathway	Biological process	-
RORC	6097	RAR-related orphan receptor C	steroid hormone receptor activity	Molecular function	-
ZNF792	126375	zinc finger protein 792	DNA binding	Molecular function	-
PKIG	11142	protein kinase (cAMP-dependent, catalytic) inhibitor gamma	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
SLC35F4	341880	solute carrier family 35, member F4	integral component of membrane	Cellular component	-
ARMT1	79624	acidic residue methyltransferase 1	S-adenosylmethionine-dependent methyltransferase activity	Molecular function	25732820
CTBP2	1488	C-terminal binding protein 2	retinoic acid receptor binding	Molecular function	-
T	6862	T, brachyury homolog (mouse)	determination of heart left/right asymmetry	Biological process	-
TFDP1	7027	transcription factor Dp-1	regulation of transcription from RNA polymerase II promoter	Biological process	8405995
MTHFR	4524	methylenetetrahydrofolate reductase (NAD(P)H)	methylenetetrahydrofolate reductase (NAD(P)H) activity	Molecular function	-
HAUS4	54930	HAUS augmin-like complex, subunit 4	cytoplasm	Cellular component	-
EBF2	64641	early B-cell factor 2	chromatin binding	Molecular function	-
EPDR1	54749	ependymin related 1	cell-matrix adhesion	Biological process	-
BAX	581	BCL2-associated X protein	protein binding	Molecular function	10753914
COQ3	51805	coenzyme Q3 methyltransferase	ubiquinone biosynthetic process	Biological process	-
RHOG	391	ras homolog family member G	regulation of ruffle assembly	Biological process	-
TEK	7010	TEK tyrosine kinase, endothelial	substrate adhesion-dependent cell spreading	Biological process	18425119
MYL7	58498	myosin, light chain 7, regulatory	calcium ion binding	Molecular function	-
WNT6	7475	wingless-type MMTV integration site family, member 6	proteinaceous extracellular matrix	Cellular component	-
CCDC60	160777	coiled-coil domain containing 60	protein binding	Molecular function	25416956
SLC44A4	80736	solute carrier family 44, member 4	phospholipid metabolic process	Biological process	-
TEAD2	8463	TEA domain family member 2	nucleus	Cellular component	8702974
FOXJ1	2302	forkhead box J1	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
PRKACG	5568	protein kinase, cAMP-dependent, catalytic, gamma	epidermal growth factor receptor signaling pathway	Biological process	-
SLA2	84174	Src-like-adaptor 2	endosome membrane	Cellular component	11696592
PRDM16	63976	PR domain containing 16	SMAD binding	Molecular function	-
URI1	8725	URI1, prefoldin-like chaperone	negative regulation of intrinsic apoptotic signaling pathway	Biological process	17936702
ZGLP1	100125288	zinc finger, GATA-like protein 1	sequence-specific DNA binding transcription factor activity	Molecular function	-
GPR180	160897	G protein-coupled receptor 180	response to pheromone	Biological process	-
CDKN2A	1029	cyclin-dependent kinase inhibitor 2A	Ras protein signal transduction	Biological process	9054499
CDKN1A	1026	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	cytosol	Cellular component	-
ADAM9	8754	ADAM metallopeptidase domain 9	metallopeptidase activity	Molecular function	12535668
ALOX15B	247	arachidonate 15-lipoxygenase, type B	extracellular exosome	Cellular component	23533145
RAB13	5872	RAB13, member RAS oncogene family	cytoplasmic vesicle	Cellular component	8294494
CCL5	6352	chemokine (C-C motif) ligand 5	chemokine activity	Molecular function	7524281
RPS18	6222	ribosomal protein S18	small ribosomal subunit	Cellular component	15883184
OR8D2	283160	olfactory receptor, family 8, subfamily D, member 2 (gene/pseudogene)	olfactory receptor activity	Molecular function	-
HEY2	23493	hes-related family bHLH transcription factor with YRPW motif 2	negative regulation of cardiac muscle cell apoptotic process	Biological process	-
PHOX2B	8929	paired-like homeobox 2b	regulation of respiratory gaseous exchange by neurological system process	Biological process	-
FOXC1	2296	forkhead box C1	regulation of blood vessel size	Biological process	-
INSR	3643	insulin receptor	positive regulation of glucose import	Biological process	11001060
PSMA6	5687	proteasome (prosome, macropain) subunit, alpha type, 6	stimulatory C-type lectin receptor signaling pathway	Biological process	-
OR2T11	127077	olfactory receptor, family 2, subfamily T, member 11 (gene/pseudogene)	olfactory receptor activity	Molecular function	-
CXCL6	6372	chemokine (C-X-C motif) ligand 6	chemokine-mediated signaling pathway	Biological process	-
ZPR1	8882	ZPR1 zinc finger	Cajal body organization	Biological process	-
CASP5	838	caspase 5, apoptosis-related cysteine peptidase	scaffold protein binding	Molecular function	-
CD177	57126	CD177 molecule	extracellular exosome	Cellular component	23533145
NDUFA8	4702	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa	respiratory electron transport chain	Biological process	-
BCL6	604	B-cell CLL/lymphoma 6	cellular response to DNA damage stimulus	Biological process	15577913
RGS7	6000	regulator of G-protein signaling 7	signal transducer activity	Molecular function	-
AMDHD1	144193	amidohydrolase domain containing 1	cellular nitrogen compound metabolic process	Biological process	-
ITGB4	3691	integrin, beta 4	mesodermal cell differentiation	Biological process	23154389
SGCG	6445	sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)	sarcolemma	Cellular component	-
SORCS2	57537	sortilin-related VPS10 domain containing receptor 2	integral component of membrane	Cellular component	-
RPP21	79897	ribonuclease P/MRP 21kDa subunit	nucleolar ribonuclease P complex	Cellular component	-
NKIRAS2	28511	NFKB inhibitor interacting Ras-like 2	GTP binding	Molecular function	-
WNT5A	7474	wingless-type MMTV integration site family, member 5A	positive regulation of cell-cell adhesion mediated by cadherin	Biological process	-
PLA2G6	8398	phospholipase A2, group VI (cytosolic, calcium-independent)	positive regulation of release of cytochrome c from mitochondria	Biological process	-
CHEK1	1111	checkpoint kinase 1	chromatin	Cellular component	-
PLA2G5	5322	phospholipase A2, group V	Golgi apparatus	Cellular component	-
ADPRHL2	54936	ADP-ribosylhydrolase like 2	poly(ADP-ribose) glycohydrolase activity	Molecular function	-
RAB3GAP1	22930	RAB3 GTPase activating protein subunit 1 (catalytic)	hypothalamus development	Biological process	20512159
MAP3K11	4296	mitogen-activated protein kinase kinase kinase 11	membrane	Cellular component	19946888
BDKRB2	624	bradykinin receptor B2	protein heterodimerization activity	Molecular function	10993080
TCF7L1	83439	transcription factor 7-like 1 (T-cell specific, HMG-box)	canonical Wnt signaling pathway	Biological process	-
OR3A3	8392	olfactory receptor, family 3, subfamily A, member 3	detection of chemical stimulus involved in sensory perception	Biological process	-
ADH4	127	alcohol dehydrogenase 4 (class II), pi polypeptide	retinoid metabolic process	Biological process	15369820
PON2	5445	paraoxonase 2	extracellular region	Cellular component	-
BCL11A	53335	B-cell CLL/lymphoma 11A (zinc finger protein)	negative regulation of neuron projection development	Biological process	19616629
MGAT5	4249	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase	integral component of membrane	Cellular component	-
PLK2	10769	polo-like kinase 2	negative regulation of dendritic spine development	Biological process	-
AGA	175	aspartylglucosaminidase	extracellular exosome	Cellular component	23376485
UCN3	114131	urocortin 3	extracellular space	Cellular component	-
PROCR	10544	protein C receptor, endothelial	negative regulation of coagulation	Biological process	19696402
CFH	3075	complement factor H	heparan sulfate proteoglycan binding	Molecular function	22471560
ATP6AP1	537	ATPase, H+ transporting, lysosomal accessory protein 1	positive regulation of ERK1 and ERK2 cascade	Biological process	-
WSB1	26118	WD repeat and SOCS box containing 1	biological_process	Biological process	-
CNKSR2	22866	connector enhancer of kinase suppressor of Ras 2	neuronal cell body	Cellular component	-
BCAS3	54828	breast carcinoma amplified sequence 3	negative regulation of GTPase activity	Biological process	-
SLC10A2	6555	solute carrier family 10 (sodium/bile acid cotransporter), member 2	proteasome complex	Cellular component	-
EXOSC3	51010	exosome component 3	cytoplasm	Cellular component	17545563
LOXL3	84695	lysyl oxidase-like 3	scavenger receptor activity	Molecular function	-
CD36	948	CD36 molecule (thrombospondin receptor)	small molecule metabolic process	Biological process	-
NAIP	4671	NLR family, apoptosis inhibitory protein	extracellular exosome	Cellular component	23376485
IFNA2	3440	interferon, alpha 2	cell surface receptor signaling pathway	Biological process	6158094
GAPVD1	26130	GTPase activating protein and VPS9 domains 1	endosome	Cellular component	-
PRKCG	5582	protein kinase C, gamma	innervation	Biological process	-
LHX5	64211	LIM homeobox 5	hippocampus development	Biological process	-
MPV17	4358	MpV17 mitochondrial inner membrane protein	mitochondrion	Cellular component	16582910
BSND	7809	barttin CLCNK-type chloride channel accessory beta subunit	cytoplasm	Cellular component	-
GSS	2937	glutathione synthetase	response to nutrient levels	Biological process	-
GLTSCR2	29997	glioma tumor suppressor candidate region gene 2	nucleolus	Cellular component	-
CDC6	990	cell division cycle 6	spindle pole	Cellular component	21041660
FFAR1	2864	free fatty acid receptor 1	response to fatty acid	Biological process	24130766
VPS4B	9525	vacuolar protein sorting 4 homolog B (S. cerevisiae)	cytosol	Cellular component	-
CNBP	7555	CCHC-type zinc finger, nucleic acid binding protein	nucleus	Cellular component	-
ZNF101	94039	zinc finger protein 101	transcription, DNA-templated	Biological process	-
OR5H14	403273	olfactory receptor, family 5, subfamily H, member 14	plasma membrane	Cellular component	-
ANKRD54	129138	ankyrin repeat domain 54	protein binding	Molecular function	25416956
DAG1	1605	dystroglycan 1 (dystrophin-associated glycoprotein 1)	negative regulation of protein kinase B signaling	Biological process	19587235
N4BP1	9683	NEDD4 binding protein 1	negative regulation of protein ubiquitination	Biological process	-
GAK	2580	cyclin G associated kinase	membrane	Cellular component	19946888
KRBOX1	100506243	KRAB box domain containing 1	nucleic acid binding	Molecular function	-
FZD5	7855	frizzled class receptor 5	embryonic camera-type eye development	Biological process	-
OGT	8473	O-linked N-acetylglucosamine (GlcNAc) transferase	apoptotic process	Biological process	20824293
HRH3	11255	histamine receptor H3	negative regulation of serotonin secretion	Biological process	-
TMBIM6	7009	transmembrane BAX inhibitor motif containing 6	endoplasmic reticulum calcium ion homeostasis	Biological process	-
KAT2B	8850	K(lysine) acetyltransferase 2B	protein acetylation	Biological process	8684459
TSPYL4	23270	TSPY-like 4	nucleus	Cellular component	-
APOL2	23780	apolipoprotein L, 2	receptor binding	Molecular function	11374903
TNFSF4	7292	tumor necrosis factor (ligand) superfamily, member 4	positive regulation of immunoglobulin mediated immune response	Biological process	-
ZBTB20	26137	zinc finger and BTB domain containing 20	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
PCNA	5111	proliferating cell nuclear antigen	chromatin binding	Molecular function	24939902
STOML2	30968	stomatin (EPB72)-like 2	immunological synapse	Cellular component	22623988
ATP6V0E2	155066	ATPase, H+ transporting V0 subunit e2	cell growth	Biological process	17350184
ATR	545	ATR serine/threonine kinase	Golgi apparatus	Cellular component	-
STK26	51765	serine/threonine protein kinase 26	nucleus	Cellular component	-
CHCHD10	400916	coiled-coil-helix-coiled-coil-helix domain containing 10	mitochondrion organization	Biological process	24934289
APOH	350	apolipoprotein H (beta-2-glycoprotein I)	negative regulation of smooth muscle cell apoptotic process	Biological process	15534879
TRAF2	7186	TNF receptor-associated factor 2	positive regulation of interleukin-2 production	Biological process	15125833
GPIHBP1	338328	glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1	lipid binding	Molecular function	-
CREB1	1385	cAMP responsive element binding protein 1	response to organic substance	Biological process	8798441
IDO2	169355	indoleamine 2,3-dioxygenase 2	oxidation-reduction process	Biological process	-
RFC4	5984	replication factor C (activator 1) 4, 37kDa	translesion synthesis	Biological process	-
SLC22A4	6583	solute carrier family 22 (organic cation/zwitterion transporter), member 4	integral component of plasma membrane	Cellular component	9426230
ZNF414	84330	zinc finger protein 414	regulation of transcription, DNA-templated	Biological process	-
RP2	6102	retinitis pigmentosa 2 (X-linked recessive)	protein transport	Biological process	-
SRC	6714	SRC proto-oncogene, non-receptor tyrosine kinase	signal transduction	Biological process	10734107
ATP13A5	344905	ATPase type 13A5	ion transmembrane transport	Biological process	-
NF1	4763	neurofibromin 1	positive regulation of neuron apoptotic process	Biological process	-
XAB2	56949	XPA binding protein 2	protein binding	Molecular function	10944529
ARHGEF15	22899	Rho guanine nucleotide exchange factor (GEF) 15	GTPase activator activity	Molecular function	-
CCR4	1233	chemokine (C-C motif) receptor 4	neuronal cell body	Cellular component	-
ITSN1	6453	intersectin 1 (SH3 domain protein)	regulation of small GTPase mediated signal transduction	Biological process	-
ANGPT2	285	angiopoietin 2	response to mechanical stimulus	Biological process	-
GRK1	6011	G protein-coupled receptor kinase 1	regulation of G-protein coupled receptor protein signaling pathway	Biological process	1656454
SPDL1	54908	spindle apparatus coiled-coil protein 1	spindle pole	Cellular component	19468067
IST1	9798	increased sodium tolerance 1 homolog (yeast)	abscission	Biological process	19525971
PMS2P3	5387	postmeiotic segregation increased 2 pseudogene 3	biological_process	Biological process	-
STARD13	90627	StAR-related lipid transfer (START) domain containing 13	lipid binding	Molecular function	-
SOX10	6663	SRY (sex determining region Y)-box 10	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity	Molecular function	-
MRPL32	64983	mitochondrial ribosomal protein L32	mitochondrial translational initiation	Biological process	-
AGGF1	55109	angiogenic factor with G patch and FHA domains 1	positive regulation of endothelial cell proliferation	Biological process	14961121
APOBEC3A	200315	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A	DNA cytosine deamination	Biological process	20062055
DCC	1630	DCC netrin 1 receptor	growth cone membrane	Cellular component	-
RPA1	6117	replication protein A1, 70kDa	nucleotide-excision repair, DNA damage removal	Biological process	-
ADORA1	134	adenosine A1 receptor	plasma membrane	Cellular component	-
MAGEA2B	266740	melanoma antigen family A2B	protein binding	Molecular function	16847267
SLCO4C1	353189	solute carrier organic anion transporter family, member 4C1	spermatogenesis	Biological process	-
EFNA3	1944	ephrin-A3	integral component of plasma membrane	Cellular component	8660976
WRN	7486	Werner syndrome, RecQ helicase-like	ATPase activity	Molecular function	10373438
TBCE	6905	tubulin folding cofactor E	muscle atrophy	Biological process	-
TNFAIP3	7128	tumor necrosis factor, alpha-induced protein 3	inflammatory response	Biological process	-
PTCHD2	57540	patched domain containing 2	regulation of lipid transport	Biological process	15645143
BMI1	648	BMI1 proto-oncogene, polycomb ring finger	positive regulation of fibroblast proliferation	Biological process	17420273
KCTD15	79047	potassium channel tetramerization domain containing 15	protein binding	Molecular function	25416956
CRHR1	1394	corticotropin releasing hormone receptor 1	hypothalamus development	Biological process	-
PRDX4	10549	peroxiredoxin 4	smooth endoplasmic reticulum	Cellular component	-
REV3L	5980	REV3-like, polymerase (DNA directed), zeta, catalytic subunit	translesion synthesis	Biological process	-
MAPK3	5595	mitogen-activated protein kinase 3	toll-like receptor 9 signaling pathway	Biological process	-
PKD1	5310	polycystic kidney disease 1 (autosomal dominant)	kidney development	Biological process	-
INPP4B	8821	inositol polyphosphate-4-phosphatase, type II, 105kDa	regulation of bone remodeling	Biological process	-
RPL11	6135	ribosomal protein L11	ribosomal large subunit biogenesis	Biological process	18697920
STON2	85439	stonin 2	intracellular protein transport	Biological process	-
COL5A1	1289	collagen, type V, alpha 1	platelet-derived growth factor binding	Molecular function	8900172
KDM1A	23028	lysine (K)-specific demethylase 1A	histone demethylase activity (H3-dimethyl-K4 specific)	Molecular function	20228790
GFER	2671	growth factor, augmenter of liver regeneration	protein binding	Molecular function	12681488
TUB	7275	tubby bipartite transcription factor	cytoplasm	Cellular component	11000483
CSMD3	114788	CUB and Sushi multiple domains 3	plasma membrane	Cellular component	-
PSKH1	5681	protein serine kinase H1	plasma membrane	Cellular component	-
SLC35C2	51006	solute carrier family 35 (GDP-fucose transporter), member C2	anion transmembrane transport	Biological process	-
EDC4	23644	enhancer of mRNA decapping 4	biological_process	Biological process	-
ZNHIT6	54680	zinc finger, HIT-type containing 6	ribosome biogenesis	Biological process	-
SLC11A2	4891	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2	transition metal ion transmembrane transporter activity	Molecular function	25326704
NUP37	79023	nucleoporin 37kDa	condensed chromosome kinetochore	Cellular component	-
OR4K15	81127	olfactory receptor, family 4, subfamily K, member 15	integral component of membrane	Cellular component	-
KIR2DL4	3805	killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4	signal transduction	Biological process	8946682
FUT4	2526	fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)	membrane	Cellular component	1716630
CCAR2	57805	cell cycle and apoptosis regulator 2	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	Biological process	23352644
PIGF	5281	phosphatidylinositol glycan anchor biosynthesis, class F	endoplasmic reticulum membrane	Cellular component	-
PGGT1B	5229	protein geranylgeranyltransferase type I, beta subunit	protein geranylgeranylation	Biological process	16893176
DDX3X	1654	DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked	positive regulation of gene expression	Biological process	10074132
WNT3A	89780	wingless-type MMTV integration site family, member 3A	frizzled-2 binding	Molecular function	-
AMH	268	anti-Mullerian hormone	aging	Biological process	-
CSTA	1475	cystatin A (stefin A)	nucleus	Cellular component	-
CEMP1	752014	cementum protein 1	cytoplasm	Cellular component	-
MAX	4149	MYC associated factor X	protein complex assembly	Biological process	-
RAPGEF2	9693	Rap guanine nucleotide exchange factor (GEF) 2	establishment of endothelial barrier	Biological process	21840392
SH3BP5L	80851	SH3-binding domain protein 5-like	negative regulation of protein tyrosine kinase activity	Biological process	-
PIK3CD	5293	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	plasma membrane	Cellular component	-
WDR61	80349	WD repeat domain 61	positive regulation of histone H3-K4 methylation	Biological process	16024656
PKN2	5586	protein kinase N2	apical junction complex	Cellular component	20974804
RBX1	9978	ring-box 1, E3 ubiquitin protein ligase	Cul4B-RING E3 ubiquitin ligase complex	Cellular component	18794347
ALDH1A2	8854	aldehyde dehydrogenase 1 family, member A2	neuron differentiation	Biological process	-
MIS18BP1	55320	MIS18 binding protein 1	mitotic nuclear division	Biological process	-
POU5F1B	5462	POU class 5 homeobox 1B	regulation of transcription, DNA-templated	Biological process	1408763
CDT1	81620	chromatin licensing and DNA replication factor 1	regulation of transcription involved in G1/S transition of mitotic cell cycle	Biological process	-
ZNF28	7576	zinc finger protein 28	nucleus	Cellular component	-
PYGO1	26108	pygopus family PHD finger 1	hematopoietic progenitor cell differentiation	Biological process	-
C1QA	712	complement component 1, q subcomponent, A chain	complement activation	Biological process	-
ARHGAP32	9743	Rho GTPase activating protein 32	endosome membrane	Cellular component	-
CTSV	1515	cathepsin V	spermatogenesis	Biological process	-
NRG3	10718	neuregulin 3	pattern specification process	Biological process	-
GLUD1	2746	glutamate dehydrogenase 1	protein binding	Molecular function	16959573
DENR	8562	density-regulated protein	formation of translation preinitiation complex	Biological process	20713520
SMARCE1	6605	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	negative regulation of transcription, DNA-templated	Biological process	12192000
NLRP6	171389	NLR family, pyrin domain containing 6	negative regulation of immune response	Biological process	-
MEOX1	4222	mesenchyme homeobox 1	somite development	Biological process	-
UBE2S	27338	ubiquitin-conjugating enzyme E2S	protein K11-linked ubiquitination	Biological process	19822757
RGPD1	400966	RANBP2-like and GRIP domain containing 1	protein targeting to Golgi	Biological process	-
AXIN1	8312	axin 1	negative regulation of protein metabolic process	Biological process	-
TNK1	8711	tyrosine kinase, non-receptor, 1	hormone receptor binding	Molecular function	-
CTF1	1489	cardiotrophin 1	protein binding	Molecular function	25416956
FOXN1	8456	forkhead box N1	regulation of T cell differentiation in thymus	Biological process	-
SLC26A6	65010	solute carrier family 26 (anion exchanger), member 6	transepithelial transport	Biological process	-
RAB5A	5868	RAB5A, member RAS oncogene family	GTPase activity	Molecular function	15378032
ANKRD10	55608	ankyrin repeat domain 10	protein binding	Molecular function	25416956
BCORL1	63035	BCL6 corepressor-like 1	chromatin modification	Biological process	-
WNT5A	7474	wingless-type MMTV integration site family, member 5A	cellular response to lipopolysaccharide	Biological process	18174455
ITGA6	3655	integrin, alpha 6	ectodermal cell differentiation	Biological process	23154389
ERCC8	1161	excision repair cross-complementation group 8	ubiquitin-protein transferase activity	Molecular function	12732143
PTPRK	5796	protein tyrosine phosphatase, receptor type, K	cell migration	Biological process	15899872
ANXA2P2	304	annexin A2 pseudogene 2	cytoskeletal protein binding	Molecular function	-
PNKP	11284	polynucleotide kinase 3'-phosphatase	polynucleotide 3' dephosphorylation	Biological process	-
KLC2	64837	kinesin light chain 2	protein complex	Cellular component	-
MEF2C	4208	myocyte enhancer factor 2C	ventricular cardiac muscle cell differentiation	Biological process	-
TECRL	253017	trans-2,3-enoyl-CoA reductase-like	lipid metabolic process	Biological process	-
SYT6	148281	synaptotagmin VI	acrosomal vesicle exocytosis	Biological process	11437455
MAPK12	6300	mitogen-activated protein kinase 12	ATP binding	Molecular function	-
ALOX5AP	241	arachidonate 5-lipoxygenase-activating protein	small molecule metabolic process	Biological process	-
ERBB2	2064	erb-b2 receptor tyrosine kinase 2	positive regulation of cell growth	Biological process	21555369
DLC1	10395	DLC1 Rho GTPase activating protein	forebrain development	Biological process	-
KCND1	3750	potassium channel, voltage gated Shal related subfamily D, member 1	synaptic transmission	Biological process	-
USP17L1	401447	ubiquitin specific peptidase 17-like family member 1	endoplasmic reticulum	Cellular component	-
CALM1	801	calmodulin 1 (phosphorylase kinase, delta)	phospholipase binding	Molecular function	12821674
RPS11	6205	ribosomal protein S11	viral process	Biological process	-
SPTBN4	57731	spectrin, beta, non-erythrocytic 4	fertilization	Biological process	-
PLCXD2	257068	phosphatidylinositol-specific phospholipase C, X domain containing 2	lipid catabolic process	Biological process	-
SNX2	6643	sorting nexin 2	transferrin receptor binding	Molecular function	9819414
YWHAB	7529	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta	enzyme binding	Molecular function	17255105
DLL1	28514	delta-like 1 (Drosophila)	negative regulation of myeloid cell differentiation	Biological process	-
KCNJ2	3759	potassium channel, inwardly rectifying subfamily J, member 2	smooth endoplasmic reticulum	Cellular component	-
GABRB2	2561	gamma-aminobutyric acid (GABA) A receptor, beta 2	cellular response to histamine	Biological process	-
OVGP1	5016	oviductal glycoprotein 1, 120kDa	chitin catabolic process	Biological process	-
MALT1	10892	MALT1 paracaspase	cytosol	Cellular component	-
NMUR2	56923	neuromedin U receptor 2	plasma membrane	Cellular component	-
PCYOX1L	78991	prenylcysteine oxidase 1 like	prenylated protein catabolic process	Biological process	-
ACADVL	37	acyl-CoA dehydrogenase, very long chain	nucleus	Cellular component	-
SLC6A15	55117	solute carrier family 6 (neutral amino acid transporter), member 15	neurotransmitter:sodium symporter activity	Molecular function	-
EIF3F	8665	eukaryotic translation initiation factor 3, subunit F	eukaryotic 43S preinitiation complex	Cellular component	-
SH3RF1	57630	SH3 domain containing ring finger 1	regulation of JNK cascade	Biological process	-
CAV2	858	caveolin 2	protein binding	Molecular function	11294831
VPS45	11311	vacuolar protein sorting 45 homolog (S. cerevisiae)	vesicle docking involved in exocytosis	Biological process	-
CATIP	375307	ciliogenesis associated TTC17 interacting protein	cytoplasm	Cellular component	24475127
MAPK8IP2	23542	mitogen-activated protein kinase 8 interacting protein 2	protein complex binding	Molecular function	-
GPI	2821	glucose-6-phosphate isomerase	methylglyoxal biosynthetic process	Biological process	-
ADCY8	114	adenylate cyclase 8 (brain)	renal water homeostasis	Biological process	-
ZBTB7A	51341	zinc finger and BTB domain containing 7A	nucleus	Cellular component	-
MAPKAPK3	7867	mitogen-activated protein kinase-activated protein kinase 3	MyD88-independent toll-like receptor signaling pathway	Biological process	-
CENPE	1062	centromere protein E, 312kDa	chromosome	Cellular component	2022189
DBX1	120237	developing brain homeobox 1	ventral spinal cord interneuron specification	Biological process	-
ACER3	55331	alkaline ceramidase 3	phytosphingosine biosynthetic process	Biological process	11356846
CYP3A43	64816	cytochrome P450, family 3, subfamily A, polypeptide 43	heme binding	Molecular function	-
SIRT1	23411	sirtuin 1	regulation of smooth muscle cell apoptotic process	Biological process	-
DDR1	780	discoidin domain receptor tyrosine kinase 1	mammary gland alveolus development	Biological process	-
FMO3	2328	flavin containing monooxygenase 3	small molecule metabolic process	Biological process	-
TCEAL3	85012	transcription elongation factor A (SII)-like 3	regulation of transcription, DNA-templated	Biological process	-
NFE2L2	4780	nuclear factor, erythroid 2-like 2	regulation of removal of superoxide radicals	Biological process	-
AMH	268	anti-Mullerian hormone	extracellular region	Cellular component	14750901
HIST1H2BA	255626	histone cluster 1, H2ba	nucleoplasm	Cellular component	-
KLK1	3816	kallikrein 1	proteolysis	Biological process	-
AURKA	6790	aurora kinase A	mitotic spindle	Cellular component	-
LMTK2	22853	lemur tyrosine kinase 2	protein autophosphorylation	Biological process	12393858
RALGAPB	57148	Ral GTPase activating protein, beta subunit (non-catalytic)	activation of GTPase activity	Biological process	-
TRIT1	54802	tRNA isopentenyltransferase 1	tRNA dimethylallyltransferase activity	Molecular function	11111046
RBM4	5936	RNA binding motif protein 4	negative regulation of translation in response to stress	Biological process	17284590
RHO	6010	rhodopsin	photoreceptor outer segment membrane	Cellular component	19934218
STUB1	10273	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase	ubiquitin protein ligase activity	Molecular function	16275660
KRTAP19-7	337974	keratin associated protein 19-7	protein binding	Molecular function	25416956
PKN2	5586	protein kinase N2	nucleus	Cellular component	-
STX10	8677	syntaxin 10	SNAP receptor activity	Molecular function	-
IGF1	3479	insulin-like growth factor 1 (somatomedin C)	ERK1 and ERK2 cascade	Biological process	24508636
POLA1	5422	polymerase (DNA directed), alpha 1, catalytic subunit	G1/S transition of mitotic cell cycle	Biological process	-
PRCD	768206	progressive rod-cone degeneration	cytoplasm	Cellular component	-
NR1I2	8856	nuclear receptor subfamily 1, group I, member 2	ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity	Molecular function	12578355
MAX	4149	MYC associated factor X	response to axon injury	Biological process	-
KCNH7	90134	potassium channel, voltage gated eag related subfamily H, member 7	voltage-gated potassium channel activity	Molecular function	-
RBAK	57786	RB-associated KRAB zinc finger	nucleic acid binding	Molecular function	-
EDAR	10913	ectodysplasin A receptor	hair follicle development	Biological process	-
IFNL2	282616	interferon, lambda 2	cytokine activity	Molecular function	-
CALM3	808	calmodulin 3 (phosphorylase kinase, delta)	nucleus	Cellular component	21630459
CYFIP1	23191	cytoplasmic FMR1 interacting protein 1	innate immune response	Biological process	-
GRAMD1B	57476	GRAM domain containing 1B	integral component of membrane	Cellular component	-
ZP3	7784	zona pellucida glycoprotein 3 (sperm receptor)	manganese ion transmembrane transporter activity	Molecular function	-
CLCNKA	1187	chloride channel, voltage-sensitive Ka	voltage-gated chloride channel activity	Molecular function	-
ACTR1B	10120	ARP1 actin-related protein 1 homolog B, centractin beta (yeast)	centrosome	Cellular component	21399614
UBA52	7311	ubiquitin A-52 residue ribosomal protein fusion product 1	Notch signaling pathway	Biological process	-
MAPK15	225689	mitogen-activated protein kinase 15	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
TP73	7161	tumor protein p73	protein kinase binding	Molecular function	18174154
GSTM3	2947	glutathione S-transferase mu 3 (brain)	glutathione transferase activity	Molecular function	10587441
TMEM262	100130348	transmembrane protein 262	integral component of membrane	Cellular component	-
KCNJ11	3767	potassium channel, inwardly rectifying subfamily J, member 11	energy reserve metabolic process	Biological process	-
ADRB3	155	adrenoceptor beta 3	generation of precursor metabolites and energy	Biological process	2570461
CLDN20	49861	claudin 20	cell junction assembly	Biological process	-
PMEL	6490	premelanosome protein	plasma membrane	Cellular component	8179825
NUP54	53371	nucleoporin 54kDa	transmembrane transport	Biological process	-
XRCC3	7517	X-ray repair complementing defective repair in Chinese hamster cells 3	double-strand break repair via homologous recombination	Biological process	23149936
PRRX1	5396	paired related homeobox 1	HMG box domain binding	Molecular function	-
NLGN2	57555	neuroligin 2	integral component of plasma membrane	Cellular component	-
POTEE	445582	POTE ankyrin domain family, member E	extracellular exosome	Cellular component	23533145
NCOA6	23054	nuclear receptor coactivator 6	positive regulation of transcription, DNA-templated	Biological process	12519782
AGR2	10551	anterior gradient 2	digestive tract morphogenesis	Biological process	-
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	positive regulation of type I interferon production	Biological process	-
IFNAR1	3454	interferon (alpha, beta and omega) receptor 1	integral component of plasma membrane	Cellular component	8181059
TGFBR1	7046	transforming growth factor, beta receptor 1	artery morphogenesis	Biological process	-
EHHADH	1962	enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase	receptor binding	Molecular function	20178365
AQP2	359	aquaporin 2 (collecting duct)	protein complex	Cellular component	-
G6PC2	57818	glucose-6-phosphatase, catalytic, 2	dephosphorylation	Biological process	-
ZNF614	80110	zinc finger protein 614	biological_process	Biological process	-
VEZF1	7716	vascular endothelial zinc finger 1	regulation of transcription from RNA polymerase II promoter	Biological process	8035792
ZFP64	55734	ZFP64 zinc finger protein	metal ion binding	Molecular function	-
TCF7	6932	transcription factor 7 (T-cell specific, HMG-box)	generation of neurons	Biological process	-
MAPK8IP2	23542	mitogen-activated protein kinase 8 interacting protein 2	beta-amyloid binding	Molecular function	12023290
ATP2B2	491	ATPase, Ca++ transporting, plasma membrane 2	apical plasma membrane	Cellular component	-
PSMB5	5693	proteasome (prosome, macropain) subunit, beta type, 5	proteasome complex	Cellular component	17323924
UBE4B	10277	ubiquitination factor E4B	ubiquitin-ubiquitin ligase activity	Molecular function	-
CXCR2	3579	chemokine (C-X-C motif) receptor 2	inflammatory response	Biological process	9725262
ITGB3	3690	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	platelet alpha granule membrane	Cellular component	-
TSPAN19	144448	tetraspanin 19	integral component of membrane	Cellular component	-
YIPF6	286451	Yip1 domain family, member 6	identical protein binding	Molecular function	-
SYNE2	23224	spectrin repeat containing, nuclear envelope 2	nuclear membrane	Cellular component	-
IFT27	11020	intraflagellar transport 27	sperm midpiece	Cellular component	-
IPO9	55705	importin 9	Ran GTPase binding	Molecular function	-
SDHB	6390	succinate dehydrogenase complex, subunit B, iron sulfur (Ip)	2 iron, 2 sulfur cluster binding	Molecular function	-
BBS4	585	Bardet-Biedl syndrome 4	positive regulation of multicellular organism growth	Biological process	-
NF2	4771	neurofibromin 2 (merlin)	ectoderm development	Biological process	-
C3	718	complement component 3	positive regulation of apoptotic cell clearance	Biological process	19302245
SCN1B	6324	sodium channel, voltage gated, type I beta subunit	regulation of sodium ion transmembrane transporter activity	Biological process	19808477
NEU3	10825	sialidase 3 (membrane sialidase)	integral component of plasma membrane	Cellular component	10405317
SPHKAP	80309	SPHK1 interactor, AKAP domain containing	mitochondrion	Cellular component	-
HACL1	26061	2-hydroxyacyl-CoA lyase 1	thiamine pyrophosphate binding	Molecular function	10468558
ACAN	176	aggrecan	Golgi lumen	Cellular component	-
FZD10	11211	frizzled class receptor 10	neuron differentiation	Biological process	-
OAS3	4940	2'-5'-oligoadenylate synthetase 3, 100kDa	ATP binding	Molecular function	9880533
BOK	666	BCL2-related ovarian killer	endoplasmic reticulum membrane	Cellular component	-
PEX5	5830	peroxisomal biogenesis factor 5	protein import into peroxisome matrix	Biological process	10514471
RGS20	8601	regulator of G-protein signaling 20	positive regulation of GTPase activity	Biological process	9748279
MUC3A	4584	mucin 3A, cell surface associated	extracellular matrix structural constituent	Molecular function	10405327
CEBPB	1051	CCAAT/enhancer binding protein (C/EBP), beta	glucocorticoid receptor binding	Molecular function	-
MMP2	4313	matrix metallopeptidase 2	blood vessel maturation	Biological process	-
GIGYF2	26058	GRB10 interacting GYF protein 2	spinal cord motor neuron differentiation	Biological process	-
CCBL2	56267	cysteine conjugate-beta lyase 2	L-kynurenine metabolic process	Biological process	-
FUT3	2525	fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)	membrane	Cellular component	1977660
SERPINF2	5345	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2	positive regulation of transforming growth factor beta production	Biological process	17958745
NID2	22795	nidogen 2 (osteonidogen)	cell surface	Cellular component	-
FGF10	2255	fibroblast growth factor 10	response to lipopolysaccharide	Biological process	-
ZBTB8OS	339487	zinc finger and BTB domain containing 8 opposite strand	metal ion binding	Molecular function	-
CCR2	729230	chemokine (C-C motif) receptor 2	positive regulation of T-helper 1 type immune response	Biological process	-
TNRC6B	23112	trinucleotide repeat containing 6B	protein binding	Molecular function	17932509
CLDN4	1364	claudin 4	plasma membrane	Cellular component	9334247
CREBBP	1387	CREB binding protein	transcription factor binding	Molecular function	15509593
EXOC7	23265	exocyst complex component 7	plasma membrane	Cellular component	-
SIDT2	51092	SID1 transmembrane family, member 2	dsRNA transport	Biological process	-
PCBD2	84105	pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2	protein homotetramerization	Biological process	-
ZXDC	79364	ZXD family zinc finger C	metal ion binding	Molecular function	-
AKT3	10000	v-akt murine thymoma viral oncogene homolog 3	plasma membrane	Cellular component	-
HIST1H2BG	8339	histone cluster 1, H2bg	extracellular exosome	Cellular component	20458337
ACADM	34	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	cellular lipid metabolic process	Biological process	-
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	stem cell maintenance	Biological process	22723415
OXTR	5021	oxytocin receptor	suckling behavior	Biological process	-
UGT8	7368	UDP glycosyltransferase 8	UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity	Molecular function	-
TSC1	7248	tuberous sclerosis 1	potassium ion transport	Biological process	-
AGPAT1	10554	1-acylglycerol-3-phosphate O-acyltransferase 1	integral component of membrane	Cellular component	-
NUP88	4927	nucleoporin 88kDa	transporter activity	Molecular function	9049309
PIR	8544	pirin (iron-binding nuclear protein)	regulation of transcription, DNA-templated	Biological process	-
UTP3	57050	UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)	chromatin modification	Biological process	-
MRPL9	65005	mitochondrial ribosomal protein L9	mitochondrial ribosome	Cellular component	11543634
ULK4	54986	unc-51 like kinase 4	regulation of p38MAPK cascade	Biological process	24284070
PML	5371	promyelocytic leukemia	negative regulation of viral release from host cell	Biological process	18248090
ZNF175	7728	zinc finger protein 175	DNA binding	Molecular function	-
PSMA2	5683	proteasome (prosome, macropain) subunit, alpha type, 2	stimulatory C-type lectin receptor signaling pathway	Biological process	-
WBSCR27	155368	Williams Beuren syndrome chromosome region 27	methylation	Biological process	-
EEF2	1938	eukaryotic translation elongation factor 2	ribonucleoprotein complex	Cellular component	18809582
SSTR3	6753	somatostatin receptor 3	integral component of plasma membrane	Cellular component	1337145
PML	5371	promyelocytic leukemia	positive regulation of defense response to virus by host	Biological process	16873256
LYZL6	57151	lysozyme-like 6	lysozyme activity	Molecular function	-
COL5A2	1290	collagen, type V, alpha 2	extracellular matrix organization	Biological process	-
ACTR3	10096	ARP3 actin-related protein 3 homolog (yeast)	cilium morphogenesis	Biological process	20393563
VEGFC	7424	vascular endothelial growth factor C	growth factor activity	Molecular function	-
RRP9	9136	ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)	small-subunit processome	Cellular component	-
VEGFA	7422	vascular endothelial growth factor A	positive regulation of protein phosphorylation	Biological process	18386220
SYT11	23208	synaptotagmin XI	calcium ion binding	Molecular function	-
SLC6A3	6531	solute carrier family 6 (neurotransmitter transporter), member 3	response to cAMP	Biological process	-
HEXB	3074	hexosaminidase B (beta polypeptide)	hyaluronan catabolic process	Biological process	-
HOXC8	3224	homeobox C8	nucleoplasm	Cellular component	-
RIMS3	9783	regulating synaptic membrane exocytosis 3	calcium ion-dependent exocytosis	Biological process	-
GHRL	51738	ghrelin/obestatin prepropeptide	extracellular region	Cellular component	-
CHID1	66005	chitinase domain containing 1	trans-Golgi network	Cellular component	16357325
GSR	2936	glutathione reductase	nucleobase-containing small molecule interconversion	Biological process	-
PSMA3	5684	proteasome (prosome, macropain) subunit, alpha type, 3	apoptotic process	Biological process	-
ATP6V1B1	525	ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1	inner ear morphogenesis	Biological process	19639346
GDF3	9573	growth differentiation factor 3	mesoderm development	Biological process	-
ESRP2	80004	epithelial splicing regulatory protein 2	RNA splicing	Biological process	-
SREBF1	6720	sterol regulatory element binding transcription factor 1	regulation of fatty acid metabolic process	Biological process	-
GABRG2	2566	gamma-aminobutyric acid (GABA) A receptor, gamma 2	postsynaptic membrane	Cellular component	-
RAF1	5894	Raf-1 proto-oncogene, serine/threonine kinase	apoptotic process	Biological process	8929532
NR4A2	4929	nuclear receptor subfamily 4, group A, member 2	transcription initiation from RNA polymerase II promoter	Biological process	-
PRDM5	11107	PR domain containing 5	negative regulation of transcription, DNA-templated	Biological process	17636019
MTDH	92140	metadherin	nuclear body	Cellular component	19648967
IFNK	56832	interferon, kappa	humoral immune response	Biological process	-
OTUD7B	56957	OTU deubiquitinase 7B	protein K11-linked deubiquitination	Biological process	20622874
CD300LG	146894	CD300 molecule-like family member g	IgM binding	Molecular function	-
POMGNT2	84892	protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)	endoplasmic reticulum membrane	Cellular component	-
KIF4A	24137	kinesin family member 4A	anterograde axon cargo transport	Biological process	7929562
RFC2	5982	replication factor C (activator 1) 2, 40kDa	DNA repair	Biological process	-
FGF18	8817	fibroblast growth factor 18	positive regulation of vascular endothelial growth factor receptor signaling pathway	Biological process	-
C19orf33	64073	chromosome 19 open reading frame 33	double-stranded DNA binding	Molecular function	11080599
TCF21	6943	transcription factor 21	respiratory system development	Biological process	-
UQCRC1	7384	ubiquinol-cytochrome c reductase core protein I	oxidative phosphorylation	Biological process	8407948
HTR3A	3359	5-hydroxytryptamine (serotonin) receptor 3A, ionotropic	transport	Biological process	7565620
TIMM21	29090	translocase of inner mitochondrial membrane 21 homolog (yeast)	mitochondrial respiratory chain complex IV assembly	Biological process	23260140
PTPRB	5787	protein tyrosine phosphatase, receptor type, B	angiogenesis	Biological process	-
SLC25A33	84275	solute carrier family 25 (pyrimidine nucleotide carrier), member 33	transcription from mitochondrial promoter	Biological process	20453889
VTCN1	79679	V-set domain containing T cell activation inhibitor 1	positive regulation of T cell proliferation	Biological process	-
ARHGEF28	64283	Rho guanine nucleotide exchange factor (GEF) 28	central nervous system neuron axonogenesis	Biological process	-
STRADA	92335	STE20-related kinase adaptor alpha	stress-activated protein kinase signaling cascade	Biological process	-
MGLL	11343	monoglyceride lipase	acylglycerol catabolic process	Biological process	-
IL1B	3553	interleukin 1, beta	positive regulation of angiogenesis	Biological process	-
LAMB2	3913	laminin, beta 2 (laminin S)	laminin-3 complex	Cellular component	10964500
AMBP	259	alpha-1-microglobulin/bikunin precursor	protein binding	Molecular function	16364318
ADAM22	53616	ADAM metallopeptidase domain 22	zinc ion binding	Molecular function	-
RHOG	391	ras homolog family member G	protein binding	Molecular function	12879077
ARHGEF5	7984	Rho guanine nucleotide exchange factor (GEF) 5	actin cytoskeleton organization	Biological process	-
UBA52	7311	ubiquitin A-52 residue ribosomal protein fusion product 1	translesion synthesis	Biological process	-
G2E3	55632	G2/M-phase specific E3 ubiquitin protein ligase	zinc ion binding	Molecular function	-
KCNC3	3748	potassium channel, voltage gated Shaw related subfamily C, member 3	axon terminus	Cellular component	-
ST3GAL4	6484	ST3 beta-galactoside alpha-2,3-sialyltransferase 4	extracellular exosome	Cellular component	23376485
CERKL	375298	ceramide kinase-like	kinase activity	Molecular function	-
OR2L13	284521	olfactory receptor, family 2, subfamily L, member 13	plasma membrane	Cellular component	-
BBS9	27241	Bardet-Biedl syndrome 9	centriolar satellite	Cellular component	23943788
JAKMIP3	282973	Janus kinase and microtubule interacting protein 3	Golgi apparatus	Cellular component	-
MAP7D3	79649	MAP7 domain containing 3	structural molecule activity	Molecular function	-
NGFR	4804	nerve growth factor receptor	nerve growth factor binding	Molecular function	-
CELSR2	1952	cadherin, EGF LAG seven-pass G-type receptor 2	dendrite morphogenesis	Biological process	-
ATOH7	220202	atonal homolog 7 (Drosophila)	cell differentiation	Biological process	-
ATP11C	286410	ATPase, class VI, type 11C	metabolic process	Biological process	-
POLR1B	84172	polymerase (RNA) I polypeptide B, 128kDa	cytoplasm	Cellular component	-
PAQR7	164091	progestin and adipoQ receptor family member VII	response to steroid hormone	Biological process	-
FRAS1	80144	Fraser extracellular matrix complex subunit 1	extracellular matrix	Cellular component	22261194
PCNA	5111	proliferating cell nuclear antigen	positive regulation of deoxyribonuclease activity	Biological process	19443450
FAH	2184	fumarylacetoacetate hydrolase (fumarylacetoacetase)	tyrosine catabolic process	Biological process	-
DSC2	1824	desmocollin 2	cardiac muscle cell-cardiac muscle cell adhesion	Biological process	21062920
SARNP	84324	SAP domain containing ribonucleoprotein	transcription export complex	Cellular component	20844015
SCNN1G	6340	sodium channel, non voltage gated 1 gamma subunit	WW domain binding	Molecular function	10642508
E2F7	144455	E2F transcription factor 7	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	-
CDCA5	113130	cell division cycle associated 5	nucleus	Cellular component	-
SMARCAL1	50485	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1	regulation of transcription from RNA polymerase II promoter	Biological process	18974355
GRIN1	2902	glutamate receptor, ionotropic, N-methyl D-aspartate 1	dendrite	Cellular component	10749211
PRNP	5621	prion protein	negative regulation of interleukin-17 production	Biological process	-
ABCC4	10257	ATP-binding cassette, sub-family C (CFTR/MRP), member 4	platelet dense granule membrane	Cellular component	-
ZNF593	51042	zinc finger protein 593	nucleus	Cellular component	-
PKN3	29941	protein kinase N3	protein phosphorylation	Biological process	-
SPRN	503542	shadow of prion protein homolog (zebrafish)	vesicle	Cellular component	-
CCL7	6354	chemokine (C-C motif) ligand 7	cell-cell signaling	Biological process	7916328
CDC37L1	55664	cell division cycle 37-like 1	chaperone binding	Molecular function	-
TAX1BP1	8887	Tax1 (human T-cell leukemia virus type I) binding protein 1	kinase binding	Molecular function	-
SCT	6343	secretin	pancreatic juice secretion	Biological process	11060443
AGT	183	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	positive regulation of fatty acid biosynthetic process	Biological process	-
ST3GAL3	6487	ST3 beta-galactoside alpha-2,3-sialyltransferase 3	carbohydrate metabolic process	Biological process	-
ATP6AP1L	92270	ATPase, H+ transporting, lysosomal accessory protein 1-like	proton-transporting ATPase activity, rotational mechanism	Molecular function	-
AADACL4	343066	arylacetamide deacetylase-like 4	metabolic process	Biological process	-
ARL6IP1	23204	ADP-ribosylation factor-like 6 interacting protein 1	Sec61 translocon complex	Cellular component	-
SNPH	9751	syntaphilin	neurotransmitter secretion	Biological process	10707983
HVCN1	84329	hydrogen voltage gated channel 1	ion transmembrane transport	Biological process	-
RACGAP1	29127	Rac GTPase activating protein 1	extracellular exosome	Cellular component	19199708
TMEM56	148534	transmembrane protein 56	integral component of membrane	Cellular component	-
CAPN1	823	calpain 1, (mu/I) large subunit	membrane	Cellular component	14559243
MYSM1	114803	Myb-like, SWIRM and MPN domains 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	17707232
SSRP1	6749	structure specific recognition protein 1	chromosome	Cellular component	-
DHX58	79132	DEXH (Asp-Glu-X-His) box polypeptide 58	helicase activity	Molecular function	-
HIF1AN	55662	hypoxia inducible factor 1, alpha subunit inhibitor	negative regulation of Notch signaling pathway	Biological process	18299578
CLDN20	49861	claudin 20	bicellular tight junction	Cellular component	-
MED25	81857	mediator complex subunit 25	retinoid X receptor binding	Molecular function	17641689
PTPN14	5784	protein tyrosine phosphatase, non-receptor type 14	receptor tyrosine kinase binding	Molecular function	20826270
DLG4	1742	discs, large homolog 4 (Drosophila)	voltage-gated potassium channel complex	Cellular component	-
DHRS1	115817	dehydrogenase/reductase (SDR family) member 1	mitochondrial inner membrane	Cellular component	-
CD2AP	23607	CD2-associated protein	extracellular exosome	Cellular component	19056867
CCDC79	283847	coiled-coil domain containing 79	meiotic telomere clustering	Biological process	-
COPS5	10987	COP9 signalosome subunit 5	metal ion binding	Molecular function	-
DNMT3A	1788	DNA (cytosine-5-)-methyltransferase 3 alpha	hypermethylation of CpG island	Biological process	-
SATB1	6304	SATB homeobox 1	programmed cell death	Biological process	-
EIF2AK3	9451	eukaryotic translation initiation factor 2-alpha kinase 3	positive regulation of transcription from RNA polymerase I promoter	Biological process	22915762
DYNC2LI1	51626	dynein, cytoplasmic 2, light intermediate chain 1	motor activity	Molecular function	-
JMJD6	23210	jumonji domain containing 6	histone H3-R2 demethylation	Biological process	17947579
AKT1	207	v-akt murine thymoma viral oncogene homolog 1	Fc-epsilon receptor signaling pathway	Biological process	-
NXPE4	54827	neurexophilin and PC-esterase domain family, member 4	biological_process	Biological process	-
HSD17B3	3293	hydroxysteroid (17-beta) dehydrogenase 3	steroid metabolic process	Biological process	-
ERCC1	2067	excision repair cross-complementation group 1	isotype switching	Biological process	-
B4GALT6	9331	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6	glycosaminoglycan metabolic process	Biological process	-
ERBB2	2064	erb-b2 receptor tyrosine kinase 2	ErbB-3 class receptor binding	Molecular function	9590694
NAPSA	9476	napsin A aspartic peptidase	peptidase activity	Molecular function	18216060
NUP37	79023	nucleoporin 37kDa	nucleoplasm	Cellular component	-
DNAJB8	165721	DnaJ (Hsp40) homolog, subfamily B, member 8	protein binding involved in protein folding	Molecular function	23612975
FCGR1C	100132417	Fc fragment of IgG, high affinity Ic, receptor (CD64), pseudogene	plasma membrane	Cellular component	-
DRD2	1813	dopamine receptor D2	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
RAB13	5872	RAB13, member RAS oncogene family	GTP binding	Molecular function	20937701
RAB42	115273	RAB42, member RAS oncogene family	membrane	Cellular component	-
ZAP70	7535	zeta-chain (TCR) associated protein kinase 70kDa	T cell migration	Biological process	20135127
RAB1A	5861	RAB1A, member RAS oncogene family	growth hormone secretion	Biological process	22939626
LTBP2	4053	latent transforming growth factor beta binding protein 2	protein targeting	Biological process	7798248
UGP2	7360	UDP-glucose pyrophosphorylase 2	glucose metabolic process	Biological process	-
TCF3	6929	transcription factor 3	cell development	Biological process	-
FAM3C	10447	family with sequence similarity 3, member C	extracellular region	Cellular component	12160727
PARK2	5071	parkin RBR E3 ubiquitin protein ligase	positive regulation of mitochondrial fusion	Biological process	23453807
RHOC	389	ras homolog family member C	extracellular exosome	Cellular component	19056867
BMP4	652	bone morphogenetic protein 4	negative regulation of apoptotic process	Biological process	17992660
NDUFV2	4729	NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa	nervous system development	Biological process	9570948
CMTM7	112616	CKLF-like MARVEL transmembrane domain containing 7	cytokine activity	Molecular function	-
KDM4D	55693	lysine (K)-specific demethylase 4D	metal ion binding	Molecular function	-
ELF3	1999	E74-like factor 3 (ets domain transcription factor, epithelial-specific )	protein binding	Molecular function	10391676
RAB3A	5864	RAB3A, member RAS oncogene family	synaptic vesicle	Cellular component	-
CHST5	23563	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5	N-acetylglucosamine 6-O-sulfotransferase activity	Molecular function	10491328
GPR4	2828	G protein-coupled receptor 4	plasma membrane	Cellular component	-
GABRB2	2561	gamma-aminobutyric acid (GABA) A receptor, beta 2	synaptic transmission, GABAergic	Biological process	-
KCNG1	3755	potassium channel, voltage gated modifier subfamily G, member 1	potassium channel activity	Molecular function	9434767
HIST1H2BG	8339	histone cluster 1, H2bg	extracellular space	Cellular component	12860195
HSCB	150274	HscB mitochondrial iron-sulfur cluster co-chaperone	plasma membrane	Cellular component	-
TRAF3IP2	10758	TRAF3 interacting protein 2	protein binding	Molecular function	12459498
HTR3D	200909	5-hydroxytryptamine (serotonin) receptor 3D, ionotropic	integral component of membrane	Cellular component	-
UQCRC2	7385	ubiquinol-cytochrome c reductase core protein II	metal ion binding	Molecular function	-
SCYL2	55681	SCY1-like 2 (S. cerevisiae)	negative regulation of canonical Wnt signaling pathway	Biological process	19643732
EIF2B2	8892	eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa	S-methyl-5-thioribose-1-phosphate isomerase activity	Molecular function	-
SCFD1	23256	sec1 family domain containing 1	Golgi cisterna membrane	Cellular component	-
RAC1	5879	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	endoplasmic reticulum membrane	Cellular component	-
PRKCE	5581	protein kinase C, epsilon	negative regulation of sodium ion transmembrane transporter activity	Biological process	19193863
PTK2	5747	protein tyrosine kinase 2	establishment of cell polarity	Biological process	19525103
CLCA3P	9629	chloride channel accessory 3, pseudogene	transport	Biological process	10095065
NUPR1	26471	nuclear protein, transcriptional regulator, 1	regulation of female gonad development	Biological process	-
ZNF750	79755	zinc finger protein 750	core promoter sequence-specific DNA binding	Molecular function	22364861
CCR2	729230	chemokine (C-C motif) receptor 2	integral component of plasma membrane	Cellular component	8146186
SLC1A3	6507	solute carrier family 1 (glial high affinity glutamate transporter), member 3	D-aspartate import	Biological process	7521911
VRK1	7443	vaccinia related kinase 1	Golgi stack	Cellular component	19103756
SPI1	6688	Spi-1 proto-oncogene	core promoter binding	Molecular function	20139074
KLK5	25818	kallikrein-related peptidase 5	protein binding	Molecular function	19194479
FOXP1	27086	forkhead box P1	osteoclast development	Biological process	18799727
RARB	5915	retinoic acid receptor, beta	positive regulation of cell proliferation	Biological process	-
CA5B	11238	carbonic anhydrase VB, mitochondrial	small molecule metabolic process	Biological process	-
SENP2	59343	SUMO1/sentrin/SMT3 specific peptidase 2	negative regulation of protein binding	Biological process	-
RARB	5915	retinoic acid receptor, beta	negative regulation of apoptotic process	Biological process	-
PADI6	353238	peptidyl arginine deiminase, type VI	nucleus	Cellular component	-
APEX1	328	APEX nuclease (multifunctional DNA repair enzyme) 1	phosphoric diester hydrolase activity	Molecular function	11478795
RPS15	6209	ribosomal protein S15	translational termination	Biological process	-
GUCY1B3	2983	guanylate cyclase 1, soluble, beta 3	intracellular membrane-bounded organelle	Cellular component	-
SLC12A6	9990	solute carrier family 12 (potassium/chloride transporter), member 6	chloride transmembrane transport	Biological process	-
HIST1H2BJ	8970	histone cluster 1, H2bj	nucleosome assembly	Biological process	6647026
SRGAP2	23380	SLIT-ROBO Rho GTPase activating protein 2	Rac GTPase binding	Molecular function	20810653
POLR2L	5441	polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa	DNA binding	Molecular function	-
KPNA1	3836	karyopherin alpha 1 (importin alpha 5)	nucleus	Cellular component	-
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	alpha-catenin binding	Molecular function	23136403
EGR3	1960	early growth response 3	sequence-specific DNA binding transcription factor activity	Molecular function	1906159
NUPL2	11097	nucleoporin like 2	nucleoplasm	Cellular component	-
HCLS1	3059	hematopoietic cell-specific Lyn substrate 1	positive regulation of protein kinase B signaling	Biological process	23001182
NOL3	8996	nucleolar protein 3 (apoptosis repressor with CARD domain)	protein oligomerization	Biological process	10196175
LAMA3	3909	laminin, alpha 3	regulation of cell migration	Biological process	-
DENND4A	10260	DENN/MADD domain containing 4A	transcription, DNA-templated	Biological process	-
POLA1	5422	polymerase (DNA directed), alpha 1, catalytic subunit	DNA synthesis involved in DNA repair	Biological process	1508673
INPPL1	3636	inositol polyphosphate phosphatase-like 1	SH3 domain binding	Molecular function	-
SEMA3E	9723	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E	patterning of blood vessels	Biological process	-
PIAS3	10401	protein inhibitor of activated STAT, 3	zinc ion binding	Molecular function	-
TF	7018	transferrin	transferrin transport	Biological process	-
BASP1	10409	brain abundant, membrane attached signal protein 1	thorax and anterior abdomen determination	Biological process	-
HDAC6	10013	histone deacetylase 6	beta-catenin binding	Molecular function	18356165
TRAF7	84231	TNF receptor-associated factor 7, E3 ubiquitin protein ligase	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
PSMA7	5688	proteasome (prosome, macropain) subunit, alpha type, 7	cytosol	Cellular component	-
OR7D4	125958	olfactory receptor, family 7, subfamily D, member 4	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
BECN1	8678	beclin 1, autophagy related	negative regulation of cell proliferation	Biological process	-
CRABP1	1381	cellular retinoic acid binding protein 1	retinol binding	Molecular function	-
RABGEF1	27342	RAB guanine nucleotide exchange factor (GEF) 1	recycling endosome	Cellular component	-
ABCC11	85320	ATP-binding cassette, sub-family C (CFTR/MRP), member 11	organic anion transport	Biological process	15537867
ENPP1	5167	ectonucleotide pyrophosphatase/phosphodiesterase 1	cellular response to insulin stimulus	Biological process	17849011
GRB2	2885	growth factor receptor-bound protein 2	identical protein binding	Molecular function	12577067
TK1	7083	thymidine kinase 1, soluble	phosphorylation	Biological process	-
AGO4	192670	argonaute RISC catalytic component 4	cytosol	Cellular component	-
H3F3B	3021	H3 histone, family 3B (H3.3B)	nucleosome assembly	Biological process	25615412
CDK7	1022	cyclin-dependent kinase 7	ATP binding	Molecular function	-
HCRTR1	3061	hypocretin (orexin) receptor 1	plasma membrane	Cellular component	-
TAOK2	9344	TAO kinase 2	activation of MAPKK activity	Biological process	10660600
PKD1	5310	polycystic kidney disease 1 (autosomal dominant)	cytosol	Cellular component	-
GHR	2690	growth hormone receptor	integral component of plasma membrane	Cellular component	8137822
SETD8	387893	SET domain containing (lysine methyltransferase) 8	negative regulation of transcription, DNA-templated	Biological process	18474616
SENP5	205564	SUMO1/sentrin specific peptidase 5	post-translational protein modification	Biological process	-
DNAJC2	27000	DnaJ (Hsp40) homolog, subfamily C, member 2	DNA replication	Biological process	-
FER	2241	fer (fps/fes related) tyrosine kinase	innate immune response	Biological process	-
DGCR6	8214	DiGeorge syndrome critical region gene 6	nucleus	Cellular component	-
CCL8	6355	chemokine (C-C motif) ligand 8	signal transduction	Biological process	9119400
HOXB5	3215	homeobox B5	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
DCD	117159	dermcidin	protein binding	Molecular function	25416956
DYNLL1	8655	dynein, light chain, LC8-type 1	microtubule-based process	Biological process	-
TLR4	7099	toll-like receptor 4	negative regulation of interleukin-6 production	Biological process	-
AP2S1	1175	adaptor-related protein complex 2, sigma 1 subunit	neurotrophin TRK receptor signaling pathway	Biological process	-
CCNB1	891	cyclin B1	cell division	Biological process	-
SCAMP3	10067	secretory carrier membrane protein 3	response to retinoic acid	Biological process	-
ZNF146	7705	zinc finger protein 146	DNA binding	Molecular function	-
FURIN	5045	furin (paired basic amino acid cleaving enzyme)	Golgi lumen	Cellular component	-
SLC9A1	6548	solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1	cell surface	Cellular component	-
EIF3B	8662	eukaryotic translation initiation factor 3, subunit B	translational initiation	Biological process	-
SDAD1	55153	SDA1 domain containing 1	actin cytoskeleton organization	Biological process	-
HDAC5	10014	histone deacetylase 5	response to drug	Biological process	-
SPO11	23626	SPO11 meiotic protein covalently bound to DSB	DNA catabolic process, endonucleolytic	Biological process	-
ERVK-10	100616101	endogenous retrovirus group K, member 10	RNA-dependent DNA replication	Biological process	-
STMN3	50861	stathmin-like 3	cytoplasm	Cellular component	-
MLPH	79083	melanophilin	stress fiber	Cellular component	-
MSX1	4487	msh homeobox 1	positive regulation of DNA damage response, signal transduction by p53 class mediator	Biological process	15705871
PARL	55486	presenilin associated, rhomboid-like	membrane protein proteolysis	Biological process	24522549
TEX37	200523	testis expressed 37	nucleus	Cellular component	-
SEC23B	10483	Sec23 homolog B (S. cerevisiae)	endoplasmic reticulum membrane	Cellular component	-
CASP8AP2	9994	caspase 8 associated protein 2	cytoplasm	Cellular component	12477726
CNTLN	54875	centlein, centrosomal protein	phosphorelay signal transduction system	Biological process	-
OSR2	116039	odd-skipped related transciption factor 2	positive regulation of gene expression	Biological process	-
NRF1	4899	nuclear respiratory factor 1	response to electrical stimulus	Biological process	-
PLLP	51090	plasmolipin	compact myelin	Cellular component	-
NAT10	55226	N-acetyltransferase 10 (GCN5-related)	nucleus	Cellular component	11214970
FOXD1	2297	forkhead box D1	negative regulation of transcription, DNA-templated	Biological process	-
IER3	8870	immediate early response 3	response to protozoan	Biological process	-
AGPS	8540	alkylglycerone phosphate synthase	peroxisome	Cellular component	10415121
DGKD	8527	diacylglycerol kinase, delta 130kDa	diacylglycerol kinase activity	Molecular function	12200442
BDKRB1	623	bradykinin receptor B1	protein kinase C-activating G-protein coupled receptor signaling pathway	Biological process	-
ISOC1	51015	isochorismatase domain containing 1	extracellular exosome	Cellular component	23376485
TANK	10010	TRAF family member-associated NFKB activator	TRIF-dependent toll-like receptor signaling pathway	Biological process	-
FKBP10	60681	FK506 binding protein 10, 65 kDa	protein peptidyl-prolyl isomerization	Biological process	-
FGR	2268	FGR proto-oncogene, Src family tyrosine kinase	peptidyl-tyrosine phosphorylation	Biological process	7519620
FDPS	2224	farnesyl diphosphate synthase	metal ion binding	Molecular function	-
COX4I1	1327	cytochrome c oxidase subunit IV isoform 1	transcription initiation from RNA polymerase II promoter	Biological process	-
SIRT1	23411	sirtuin 1	cellular response to hydrogen peroxide	Biological process	20027304
PSD3	23362	pleckstrin and Sec7 domain containing 3	postsynaptic density	Cellular component	-
AGGF1	55109	angiogenic factor with G patch and FHA domains 1	protein binding	Molecular function	14961121
IRAK1	3654	interleukin-1 receptor-associated kinase 1	negative regulation of NF-kappaB transcription factor activity	Biological process	10383454
PTPRC	5788	protein tyrosine phosphatase, receptor type, C	positive regulation of stem cell proliferation	Biological process	21911094
RFC5	5985	replication factor C (activator 1) 5, 36.5kDa	nucleotide-excision repair, DNA gap filling	Biological process	-
TRIM69	140691	tripartite motif containing 69	nuclear speck	Cellular component	23131556
SPRED1	161742	sprouty-related, EVH1 domain containing 1	positive regulation of DNA damage response, signal transduction by p53 class mediator	Biological process	20736167
ALAS1	211	5'-aminolevulinate synthase 1	pyridoxal phosphate binding	Molecular function	-
N4BP1	9683	NEDD4 binding protein 1	PML body	Cellular component	-
DCTD	1635	dCMP deaminase	small molecule metabolic process	Biological process	-
ZNF136	7695	zinc finger protein 136	protein binding	Molecular function	16189514
MYLK3	91807	myosin light chain kinase 3	cardiac myofibril assembly	Biological process	-
TAF7	6879	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa	histone acetyltransferase binding	Molecular function	11592977
PLA2G2A	5320	phospholipase A2, group IIA (platelets, synovial fluid)	low-density lipoprotein particle remodeling	Biological process	18827909
ALDOA	226	aldolase A, fructose-bisphosphate	striated muscle contraction	Biological process	14615364
KPNA1	3836	karyopherin alpha 1 (importin alpha 5)	cytoplasm	Cellular component	-
CST3	1471	cystatin C	cell activation	Biological process	-
UMOD	7369	uromodulin	ciliary membrane	Cellular component	-
AHI1	54806	Abelson helper integration site 1	heart looping	Biological process	-
BBS7	55212	Bardet-Biedl syndrome 7	palate development	Biological process	-
LIPG	9388	lipase, endothelial	phospholipid catabolic process	Biological process	19136670
ITGAV	3685	integrin, alpha V	ruffle membrane	Cellular component	25063885
LINGO1	84894	leucine rich repeat and Ig domain containing 1	central nervous system neuron development	Biological process	-
BAX	581	BCL2-associated X protein	regulation of protein homodimerization activity	Biological process	9111042
DMD	1756	dystrophin	sarcolemma	Cellular component	7545544
DAB1	1600	Dab, reelin signal transducer, homolog 1 (Drosophila)	cerebellum structural organization	Biological process	-
MAP1LC3A	84557	microtubule-associated protein 1 light chain 3 alpha	mitochondrion degradation	Biological process	22267086
CALCOCO2	10241	calcium binding and coiled-coil domain 2	response to interferon-gamma	Biological process	9230084
PDHB	5162	pyruvate dehydrogenase (lipoamide) beta	pyruvate dehydrogenase activity	Molecular function	19081061
ZNF446	55663	zinc finger protein 446	metal ion binding	Molecular function	-
MRPL46	26589	mitochondrial ribosomal protein L46	molecular_function	Molecular function	-
BHLHE40	8553	basic helix-loop-helix family, member e40	nucleus	Cellular component	9240428
KRT14	3861	keratin 14, type I	response to zinc ion	Biological process	-
SUGP1	57794	SURP and G patch domain containing 1	poly(A) RNA binding	Molecular function	22681889
CYTH2	9266	cytohesin 2	protein binding	Molecular function	10198630
IL12B	3593	interleukin 12B	positive regulation of inflammatory response	Biological process	16482511
SLC24A4	123041	solute carrier family 24 (sodium/potassium/calcium exchanger), member 4	transmembrane transport	Biological process	-
KCNMB4	27345	potassium channel subfamily M regulatory beta subunit 4	neuronal action potential	Biological process	10692449
NUP188	23511	nucleoporin 188kDa	small molecule metabolic process	Biological process	-
ATP1A4	480	ATPase, Na+/K+ transporting, alpha 4 polypeptide	metabolic process	Biological process	-
PLG	5340	plasminogen	extracellular space	Cellular component	16502470
NR2E1	7101	nuclear receptor subfamily 2, group E, member 1	behavioral fear response	Biological process	-
FOXO1	2308	forkhead box O1	endocrine pancreas development	Biological process	-
MRPL15	29088	mitochondrial ribosomal protein L15	mitochondrial large ribosomal subunit	Cellular component	-
MAPK3	5595	mitogen-activated protein kinase 3	stress-activated MAPK cascade	Biological process	-
SLC6A17	388662	solute carrier family 6 (neutral amino acid transporter), member 17	synaptic vesicle	Cellular component	-
BICC1	80114	BicC family RNA binding protein 1	negative regulation of canonical Wnt signaling pathway	Biological process	21922595
FOXN3	1112	forkhead box N3	mitotic G2 DNA damage checkpoint	Biological process	9154802
WASH1	100287171	WAS protein family homolog 1	alpha-tubulin binding	Molecular function	19922874
NAA10	8260	N(alpha)-acetyltransferase 10, NatA catalytic subunit	peptide-serine-N-acetyltransferase activity	Molecular function	-
MTRR	4552	5-methyltetrahydrofolate-homocysteine methyltransferase reductase	cellular nitrogen compound metabolic process	Biological process	-
FXYD1	5348	FXYD domain containing ion transport regulator 1	ion channel binding	Molecular function	-
TMEM182	130827	transmembrane protein 182	protein binding	Molecular function	25416956
MLLT4	4301	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	plasma membrane	Cellular component	-
HAO1	54363	hydroxyacid oxidase (glycolate oxidase) 1	medium-chain-(S)-2-hydroxy-acid oxidase activity	Molecular function	-
CNFN	84518	cornifelin	cytoplasm	Cellular component	-
ZNF559-ZNF177	100529215	ZNF559-ZNF177 readthrough	negative regulation of transcription from RNA polymerase II promoter	Biological process	8661005
LMAN1	3998	lectin, mannose-binding, 1	extracellular exosome	Cellular component	19199708
PDXP	57026	pyridoxal (pyridoxine, vitamin B6) phosphatase	cleavage furrow	Cellular component	15580268
BEST4	266675	bestrophin 4	biological_process	Biological process	-
BAD	572	BCL2-associated agonist of cell death	release of cytochrome c from mitochondria	Biological process	-
CES1	1066	carboxylesterase 1	epithelial cell differentiation	Biological process	21492153
DDX20	11218	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20	RNA secondary structure unwinding	Biological process	-
HERPUD2	64224	HERPUD family member 2	integral component of membrane	Cellular component	-
PAX2	5076	paired box 2	mesenchymal to epithelial transition involved in metanephros morphogenesis	Biological process	-
CYP2R1	120227	cytochrome P450, family 2, subfamily R, polypeptide 1	exogenous drug catabolic process	Biological process	-
AGTR2	186	angiotensin II receptor, type 2	nitric oxide mediated signal transduction	Biological process	17159080
PCDHGB4	8641	protocadherin gamma subfamily B, 4	plasma membrane	Cellular component	-
SYNE2	23224	spectrin repeat containing, nuclear envelope 2	LINC complex	Cellular component	18396275
SCMH1	22955	sex comb on midleg homolog 1 (Drosophila)	chromatin remodeling	Biological process	-
MTERF1	7978	mitochondrial transcription termination factor 1	regulation of transcription, DNA-templated	Biological process	-
SULT1A1	6817	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1	cytosol	Cellular component	-
SMARCA2	6595	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	nervous system development	Biological process	-
RPH3AL	9501	rabphilin 3A-like (without C2 domains)	clathrin binding	Molecular function	-
WDR82	80335	WD repeat domain 82	histone H3-K4 methylation	Biological process	17355966
NDUFA4	4697	NDUFA4, mitochondrial complex associated	respiratory electron transport chain	Biological process	-
YTHDC2	64848	YTH domain containing 2	ATP binding	Molecular function	-
CENPF	1063	centromere protein F, 350/400kDa	midbody	Cellular component	7651420
GLRA3	8001	glycine receptor, alpha 3	cell junction	Cellular component	-
PLEKHA1	59338	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	palate development	Biological process	-
CPB2	1361	carboxypeptidase B2 (plasma)	extracellular space	Cellular component	-
MTCL1	23255	microtubule crosslinking factor 1	regulation of autophagy	Biological process	-
TNFSF10	8743	tumor necrosis factor (ligand) superfamily, member 10	activation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	-
MAVS	57506	mitochondrial antiviral signaling protein	positive regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	12761501
STX4	6810	syntaxin 4	protein binding	Molecular function	12130530
SYT8	90019	synaptotagmin VIII	synaptic vesicle membrane	Cellular component	-
CHMP7	91782	charged multivesicular body protein 7	viral process	Biological process	-
CD96	10225	CD96 molecule	plasma membrane	Cellular component	-
PHPT1	29085	phosphohistidine phosphatase 1	calcium channel inhibitor activity	Molecular function	18796614
ZNF708	7562	zinc finger protein 708	metal ion binding	Molecular function	-
BCAN	63827	brevican	carbohydrate metabolic process	Biological process	-
KLHL20	27252	kelch-like family member 20	negative regulation of apoptotic process	Biological process	20389280
CLDN8	9073	claudin 8	identical protein binding	Molecular function	-
CELF1	10658	CUGBP, Elav-like family member 1	nucleus	Cellular component	10893231
PCNT	5116	pericentrin	protein binding	Molecular function	12812986
NPPC	4880	natriuretic peptide C	ossification	Biological process	-
FGF17	8822	fibroblast growth factor 17	innate immune response	Biological process	-
CRP	1401	C-reactive protein, pentraxin-related	complement component C1q binding	Molecular function	23544079
RGS12	6002	regulator of G-protein signaling 12	receptor signaling protein activity	Molecular function	-
COL4A5	1287	collagen, type IV, alpha 5	axon guidance	Biological process	-
NUP50	10762	nucleoporin 50kDa	gene expression	Biological process	-
TUFM	7284	Tu translation elongation factor, mitochondrial	translation elongation factor activity	Molecular function	9332382
DNAH17	8632	dynein, axonemal, heavy chain 17	microtubule	Cellular component	-
DUSP14	11072	dual specificity phosphatase 14	protein tyrosine phosphatase activity	Molecular function	-
ACACA	31	acetyl-CoA carboxylase alpha	biotin carboxylase activity	Molecular function	-
ITGA5	3678	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	protein binding	Molecular function	14970227
OR2S2	56656	olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene)	sensory perception of smell	Biological process	14983052
STARD9	57519	StAR-related lipid transfer (START) domain containing 9	microtubule binding	Molecular function	22153075
PODXL	5420	podocalyxin-like	plasma membrane	Cellular component	18456258
PDZD11	51248	PDZ domain containing 11	water-soluble vitamin metabolic process	Biological process	-
CRIPAK	285464	cysteine-rich PAK1 inhibitor	plasma membrane	Cellular component	16278681
OR5L1	219437	olfactory receptor, family 5, subfamily L, member 1 (gene/pseudogene)	integral component of plasma membrane	Cellular component	-
DKK1	22943	dickkopf WNT signaling pathway inhibitor 1	response to retinoic acid	Biological process	-
TFEB	7942	transcription factor EB	positive regulation of transcription from RNA polymerase II promoter	Biological process	19556463
LSM1	27257	LSM1, U6 small nuclear RNA associated	RNA splicing, via transesterification reactions	Biological process	10369684
VCAM1	7412	vascular cell adhesion molecule 1	plasma membrane	Cellular component	-
HEY2	23493	hes-related family bHLH transcription factor with YRPW motif 2	negative regulation of cardiac vascular smooth muscle cell differentiation	Biological process	-
HTR1A	3350	5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled	integral component of plasma membrane	Cellular component	22957663
EAF1	85403	ELL associated factor 1	nuclear speck	Cellular component	-
OR11H2	79334	olfactory receptor, family 11, subfamily H, member 2	plasma membrane	Cellular component	-
PRDM16	63976	PR domain containing 16	regulation of cellular respiration	Biological process	-
DHX8	1659	DEAH (Asp-Glu-Ala-His) box polypeptide 8	ATP binding	Molecular function	-
MYD88	4615	myeloid differentiation primary response 88	toll-like receptor 4 signaling pathway	Biological process	-
CHRDL1	91851	chordin-like 1	neuron differentiation	Biological process	-
METTL6	131965	methyltransferase like 6	methylation	Biological process	-
SCD5	79966	stearoyl-CoA desaturase 5	fatty acid biosynthetic process	Biological process	-
CALM3	808	calmodulin 3 (phosphorylase kinase, delta)	inositol phosphate metabolic process	Biological process	-
CHRM1	1128	cholinergic receptor, muscarinic 1	synapse	Cellular component	-
CLEC12A	160364	C-type lectin domain family 12, member A	plasma membrane	Cellular component	-
TMEM52	339456	transmembrane protein 52	integral component of membrane	Cellular component	-
BMP2K	55589	BMP2 inducible kinase	regulation of bone mineralization	Biological process	-
FUBP3	8939	far upstream element (FUSE) binding protein 3	positive regulation of gene expression	Biological process	19087307
RNF180	285671	ring finger protein 180	integral component of membrane	Cellular component	-
SH3GL3	6457	SH3-domain GRB2-like 3	identical protein binding	Molecular function	16115810
TWIST1	7291	twist family bHLH transcription factor 1	embryonic hindlimb morphogenesis	Biological process	-
POMK	84197	protein-O-mannose kinase	integral component of membrane	Cellular component	-
SELP	6403	selectin P (granule membrane protein 140kDa, antigen CD62)	calcium-dependent protein binding	Molecular function	-
FCER1G	2207	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	positive regulation of mast cell cytokine production	Biological process	-
ETS1	2113	v-ets avian erythroblastosis virus E26 oncogene homolog 1	immune response	Biological process	2187191
AQP1	358	aquaporin 1 (Colton blood group)	potassium ion transport	Biological process	-
PNN	5411	pinin, desmosome associated protein	intermediate filament	Cellular component	10809736
BCL6	604	B-cell CLL/lymphoma 6	negative regulation of B cell apoptotic process	Biological process	15577913
SLC27A6	28965	solute carrier family 27 (fatty acid transporter), member 6	integral component of membrane	Cellular component	-
PCDH11X	27328	protocadherin 11 X-linked	extracellular exosome	Cellular component	23376485
ULBP3	79465	UL16 binding protein 3	anchored component of plasma membrane	Cellular component	11239445
PSME4	23198	proteasome (prosome, macropain) activator subunit 4	positive regulation of peptidase activity	Biological process	-
HBB	3043	hemoglobin, beta	oxidation-reduction process	Biological process	19740759
MTHFD1L	25902	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like	formate-tetrahydrofolate ligase activity	Molecular function	12937168
CNTNAP2	26047	contactin associated protein-like 2	superior temporal gyrus development	Biological process	18179893
ABCB5	340273	ATP-binding cassette, sub-family B (MDR/TAP), member 5	positive regulation of antigen processing and presentation of peptide antigen via MHC class I	Biological process	-
IFITM1	8519	interferon induced transmembrane protein 1	response to interferon-beta	Biological process	21253575
RAC3	5881	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	GTPase activity	Molecular function	11956649
CTDSP2	10106	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2	nucleoplasm	Cellular component	-
ZNF648	127665	zinc finger protein 648	transcription, DNA-templated	Biological process	-
TULP3	7289	tubby like protein 3	axoneme	Cellular component	-
HAS3	3038	hyaluronan synthase 3	hyaluranon cable	Cellular component	16900089
NUBP1	4682	nucleotide binding protein 1	negative regulation of centrosome duplication	Biological process	-
MDFIC	29969	MyoD family inhibitor domain containing	transcription, DNA-templated	Biological process	-
PTMA	5757	prothymosin, alpha	nucleus	Cellular component	10854063
ELL2	22936	elongation factor, RNA polymerase II, 2	nucleoplasm	Cellular component	-
NRXN1	9378	neurexin 1	gamma-aminobutyric acid receptor clustering	Biological process	-
CLIC2	1193	chloride intracellular channel 2	positive regulation of binding	Biological process	15916532
MED13L	23389	mediator complex subunit 13-like	mediator complex	Cellular component	-
COL12A1	1303	collagen, type XII, alpha 1	collagen catabolic process	Biological process	-
HRNR	388697	hornerin	establishment of skin barrier	Biological process	23403047
AGTR1	185	angiotensin II receptor, type 1	cell chemotaxis	Biological process	15635042
SCAP	22937	SREBF chaperone	response to hypoxia	Biological process	-
STK36	27148	serine/threonine kinase 36	brain development	Biological process	-
NAA15	80155	N(alpha)-acetyltransferase 15, NatA auxiliary subunit	cytoplasm	Cellular component	-
EDNRB	1910	endothelin receptor type B	positive regulation of protein phosphorylation	Biological process	-
GPX1	2876	glutathione peroxidase 1	protein oxidation	Biological process	-
VAMP1	6843	vesicle-associated membrane protein 1 (synaptobrevin 1)	SNARE complex	Cellular component	-
TRPM1	4308	transient receptor potential cation channel, subfamily M, member 1	transport	Biological process	9806836
SLC24A2	25769	solute carrier family 24 (sodium/potassium/calcium exchanger), member 2	memory	Biological process	-
RBCK1	10616	RanBP-type and C3HC4-type zinc finger containing 1	positive regulation of NF-kappaB import into nucleus	Biological process	-
UTRN	7402	utrophin	nucleoplasm	Cellular component	-
ZNF268	10795	zinc finger protein 268	negative regulation of cell cycle arrest	Biological process	23091055
KLF1	10661	Kruppel-like factor 1 (erythroid)	erythrocyte differentiation	Biological process	21055716
DLL1	28514	delta-like 1 (Drosophila)	loop of Henle development	Biological process	-
SNAPIN	23557	SNAP-associated protein	regulation of protein binding	Biological process	23949442
REN	5972	renin	response to cAMP	Biological process	-
TXNRD2	10587	thioredoxin reductase 2	thioredoxin-disulfide reductase activity	Molecular function	-
PLEK	5341	pleckstrin	positive regulation of actin filament bundle assembly	Biological process	10497244
PMF1	11243	polyamine-modulated factor 1	mitotic cell cycle	Biological process	-
NR1H3	10062	nuclear receptor subfamily 1, group H, member 3	positive regulation of lipoprotein lipase activity	Biological process	17186944
RGCC	28984	regulator of cell cycle	positive regulation of transcription from RNA polymerase II promoter	Biological process	19158077
TUBE1	51175	tubulin, epsilon 1	GTP binding	Molecular function	-
GLUD2	2747	glutamate dehydrogenase 2	glutamate metabolic process	Biological process	8207021
ESR2	2100	estrogen receptor 2 (ER beta)	prostate gland epithelium morphogenesis	Biological process	-
ATXN7L1	222255	ataxin 7-like 1	protein binding	Molecular function	25416956
ACADL	33	acyl-CoA dehydrogenase, long chain	palmitoyl-CoA oxidase activity	Molecular function	-
C1QA	712	complement component 1, q subcomponent, A chain	cell-cell signaling	Biological process	9461517
PELI2	57161	pellino E3 ubiquitin protein ligase family member 2	positive regulation of MAPK cascade	Biological process	12804775
PTPN2	5771	protein tyrosine phosphatase, non-receptor type 2	syntaxin binding	Molecular function	23006999
SRR	63826	serine racemase	aging	Biological process	-
ETFA	2108	electron-transfer-flavoprotein, alpha polypeptide	cellular metabolic process	Biological process	-
MTIF2	4528	mitochondrial translational initiation factor 2	ribosomal small subunit binding	Molecular function	-
PEX12	5193	peroxisomal biogenesis factor 12	protein binding	Molecular function	10562279
ANGPTL3	27329	angiopoietin-like 3	positive regulation of cell migration	Biological process	11877390
NRBP1	29959	nuclear receptor binding protein 1	endomembrane system	Cellular component	11956649
PPRC1	23082	peroxisome proliferator-activated receptor gamma, coactivator-related 1	nucleus	Cellular component	-
CFLAR	8837	CASP8 and FADD-like apoptosis regulator	positive regulation of NF-kappaB transcription factor activity	Biological process	-
COQ7	10229	coenzyme Q7 homolog, ubiquinone (yeast)	determination of adult lifespan	Biological process	-
ILKAP	80895	integrin-linked kinase-associated serine/threonine phosphatase	regulation of nuclear cell cycle DNA replication	Biological process	-
FMO3	2328	flavin containing monooxygenase 3	endoplasmic reticulum membrane	Cellular component	-
NIFK	84365	nucleolar protein interacting with the FHA domain of MKI67	nucleus	Cellular component	-
ADSSL1	122622	adenylosuccinate synthase like 1	GTPase activity	Molecular function	-
UPF2	26019	UPF2 regulator of nonsense transcripts homolog (yeast)	organ regeneration	Biological process	-
PDPK1	5170	3-phosphoinositide dependent protein kinase 1	regulation of transcription, DNA-templated	Biological process	-
ANKRD1	27063	ankyrin repeat domain 1 (cardiac muscle)	small molecule metabolic process	Biological process	-
NUP54	53371	nucleoporin 54kDa	nuclear pore	Cellular component	-
BUB1B	701	BUB1 mitotic checkpoint serine/threonine kinase B	protein localization to kinetochore	Biological process	9660858
CD86	942	CD86 molecule	external side of plasma membrane	Cellular component	-
DLG1	1739	discs, large homolog 1 (Drosophila)	guanylate kinase activity	Molecular function	7937897
MICAL1	64780	microtubule associated monooxygenase, calponin and LIM domain containing 1	SH3 domain binding	Molecular function	11827972
NODAL	4838	nodal growth differentiation factor	embryonic process involved in female pregnancy	Biological process	-
ADORA2A	135	adenosine A2a receptor	G-protein coupled adenosine receptor activity	Molecular function	21393508
C3AR1	719	complement component 3a receptor 1	integral component of plasma membrane	Cellular component	8702752
IRF3	3661	interferon regulatory factor 3	negative regulation of type I interferon production	Biological process	-
MYH9	4627	myosin, heavy chain 9, non-muscle	actin-dependent ATPase activity	Molecular function	24072716
CNOT7	29883	CCR4-NOT transcription complex, subunit 7	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	Biological process	21278420
UBIAD1	29914	UbiA prenyltransferase domain containing 1	mitochondrial membrane	Cellular component	-
NAAA	27163	N-acylethanolamine acid amidase	biological_process	Biological process	-
POLR2F	5435	polymerase (RNA) II (DNA directed) polypeptide F	transcription-coupled nucleotide-excision repair	Biological process	-
PSME4	23198	proteasome (prosome, macropain) activator subunit 4	gene expression	Biological process	-
MYLK	4638	myosin light chain kinase	bleb assembly	Biological process	20181817
OR4F5	79501	olfactory receptor, family 4, subfamily F, member 5	detection of chemical stimulus involved in sensory perception	Biological process	-
POGZ	23126	pogo transposable element with ZNF domain	mitotic sister chromatid cohesion	Biological process	20562864
FTCD	10841	formimidoyltransferase cyclodeaminase	cytosol	Cellular component	-
CTF1	1489	cardiotrophin 1	muscle organ development	Biological process	7862649
ATP2B1	490	ATPase, Ca++ transporting, plasma membrane 1	calcium-transporting ATPase activity	Molecular function	-
COL4A1	1282	collagen, type IV, alpha 1	blood vessel morphogenesis	Biological process	20818663
PGAM2	5224	phosphoglycerate mutase 2 (muscle)	carbohydrate metabolic process	Biological process	-
HIRA	7290	histone cell cycle regulator	PML body	Cellular component	-
KCNA3	3738	potassium channel, voltage gated shaker related subfamily A, member 3	protein homooligomerization	Biological process	-
KCTD12	115207	potassium channel tetramerization domain containing 12	poly(A) RNA binding	Molecular function	22681889
ARGFX	503582	arginine-fifty homeobox	transcription, DNA-templated	Biological process	-
DNMT3B	1789	DNA (cytosine-5-)-methyltransferase 3 beta	nucleus	Cellular component	17303076
TCIRG1	10312	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3	transmembrane transport	Biological process	-
HAAO	23498	3-hydroxyanthranilate 3,4-dioxygenase	small molecule metabolic process	Biological process	-
TUBGCP5	114791	tubulin, gamma complex associated protein 5	microtubule nucleation	Biological process	11694571
PIGG	54872	phosphatidylinositol glycan anchor biosynthesis, class G	post-translational protein modification	Biological process	-
ARNTL	406	aryl hydrocarbon receptor nuclear translocator-like	positive regulation of transcription from RNA polymerase II promoter	Biological process	9576906
CXADR	1525	coxsackie virus and adenovirus receptor	viral entry into host cell	Biological process	-
BRK1	55845	BRICK1, SCAR/WAVE actin-nucleating complex subunit	cell motility	Biological process	-
APLN	8862	apelin	apelin receptor binding	Molecular function	-
PYURF	100996939	PIGY upstream reading frame	endoplasmic reticulum membrane	Cellular component	16162815
PDK2	5164	pyruvate dehydrogenase kinase, isozyme 2	cellular response to nutrient	Biological process	-
NCOA1	8648	nuclear receptor coactivator 1	cellular lipid metabolic process	Biological process	-
NF2	4771	neurofibromin 2 (merlin)	negative regulation of protein kinase activity	Biological process	-
STX2	2054	syntaxin 2	integral component of membrane	Cellular component	-
RPS16	6217	ribosomal protein S16	viral process	Biological process	-
PTBP2	58155	polypyrimidine tract binding protein 2	poly(A) RNA binding	Molecular function	22658674
NTRK2	4915	neurotrophic tyrosine kinase, receptor, type 2	neurotrophin binding	Molecular function	-
CREG1	8804	cellular repressor of E1A-stimulated genes 1	cell proliferation	Biological process	9710587
IL10	3586	interleukin 10	aging	Biological process	-
PTEN	5728	phosphatase and tensin homolog	postsynaptic density assembly	Biological process	-
DEFA6	1671	defensin, alpha 6, Paneth cell-specific	protein binding	Molecular function	25416956
PFKL	5211	phosphofructokinase, liver	glucose metabolic process	Biological process	-
TAF3	83860	TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa	transcription factor TFIID complex	Cellular component	11438666
CYP17A1	1586	cytochrome P450, family 17, subfamily A, polypeptide 1	sterol metabolic process	Biological process	-
KEL	3792	Kell blood group, metallo-endopeptidase	cellular magnesium ion homeostasis	Biological process	-
MECP2	4204	methyl CpG binding protein 2	cerebellum development	Biological process	-
SPTAN1	6709	spectrin, alpha, non-erythrocytic 1	protein binding	Molecular function	12571280
KANK2	25959	KN motif and ankyrin repeat domains 2	negative regulation of intracellular estrogen receptor signaling pathway	Biological process	17476305
SLC16A4	9122	solute carrier family 16, member 4	membrane	Cellular component	9425115
B3GAT1	27087	beta-1,3-glucuronyltransferase 1	glycosaminoglycan metabolic process	Biological process	-
CORO2A	7464	coronin, actin binding protein, 2A	actin cytoskeleton	Cellular component	-
SKIL	6498	SKI-like proto-oncogene	cell cycle arrest	Biological process	-
ELF1	1997	E74-like factor 1 (ets domain transcription factor)	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	8756667
NR1H4	9971	nuclear receptor subfamily 1, group H, member 4	ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity	Molecular function	21757002
MMP16	4325	matrix metallopeptidase 16 (membrane-inserted)	Golgi lumen	Cellular component	-
SPN	6693	sialophorin	extracellular space	Cellular component	10899905
CD83	9308	CD83 molecule	integral component of plasma membrane	Cellular component	8422464
BCR	613	breakpoint cluster region	enzyme binding	Molecular function	-
MICA	100507436	MHC class I polypeptide-related sequence A	antigen binding	Molecular function	-
SLC27A4	10999	solute carrier family 27 (fatty acid transporter), member 4	very long-chain fatty acid catabolic process	Biological process	-
PPP2CB	5516	protein phosphatase 2, catalytic subunit, beta isozyme	negative regulation of Ras protein signal transduction	Biological process	-
PANX2	56666	pannexin 2	wide pore channel activity	Molecular function	-
LRPPRC	10128	leucine-rich pentatricopeptide repeat containing	single-stranded DNA binding	Molecular function	-
HTRA3	94031	HtrA serine peptidase 3	serine-type peptidase activity	Molecular function	22229724
TRAT1	50852	T cell receptor associated transmembrane adaptor 1	phosphatidylinositol-mediated signaling	Biological process	-
AMELX	265	amelogenin, X-linked	proteinaceous extracellular matrix	Cellular component	2509010
HAPLN3	145864	hyaluronan and proteoglycan link protein 3	hyaluronic acid binding	Molecular function	-
CHRNB4	1143	cholinergic receptor, nicotinic, beta 4 (neuronal)	locomotory behavior	Biological process	-
CASP4	837	caspase 4, apoptosis-related cysteine peptidase	mitochondrion	Cellular component	15123740
PRPF19	27339	pre-mRNA processing factor 19	ubiquitin protein ligase activity	Molecular function	20595234
ISCU	23479	iron-sulfur cluster assembly enzyme	iron ion binding	Molecular function	11060020
RPRM	56475	reprimo, TP53 dependent G2 arrest mediator candidate	cytoplasm	Cellular component	-
MMD	23531	monocyte to macrophage differentiation-associated	cytolysis	Biological process	-
AP1G1	164	adaptor-related protein complex 1, gamma 1 subunit	Golgi membrane	Cellular component	-
PARG	8505	poly (ADP-ribose) glycohydrolase	poly(ADP-ribose) glycohydrolase activity	Molecular function	15450800
AXIN1	8312	axin 1	olfactory placode formation	Biological process	-
ALDH1A3	220	aldehyde dehydrogenase 1 family, member A3	protein homodimerization activity	Molecular function	11585737
PAK3	5063	p21 protein (Cdc42/Rac)-activated kinase 3	metal ion binding	Molecular function	-
FOXP3	50943	forkhead box P3	negative regulation of transcription, DNA-templated	Biological process	23169781
BCL10	8915	B-cell CLL/lymphoma 10	neural tube closure	Biological process	11163238
ILK	3611	integrin-linked kinase	protein phosphorylation	Biological process	10871859
RPL13AP3	645683	ribosomal protein L13a pseudogene 3	nucleus	Cellular component	21630459
FKBP1A	2280	FK506 binding protein 1A, 12kDa	amyloid fibril formation	Biological process	18346205
COPB1	1315	coatomer protein complex, subunit beta 1	viral process	Biological process	-
IGKV3D-11	28876	immunoglobulin kappa variable 3D-11	plasma membrane	Cellular component	-
TGFB1	7040	transforming growth factor, beta 1	regulation of blood vessel remodeling	Biological process	22269326
CAMK2N2	94032	calcium/calmodulin-dependent protein kinase II inhibitor 2	cytosol	Cellular component	-
SFRP2	6423	secreted frizzled-related protein 2	negative regulation of canonical Wnt signaling pathway	Biological process	-
IFNG	3458	interferon, gamma	positive regulation of interleukin-6 biosynthetic process	Biological process	-
ENPP1	5167	ectonucleotide pyrophosphatase/phosphodiesterase 1	basolateral plasma membrane	Cellular component	9553761
HIST4H4	121504	histone cluster 4, H4	gene expression	Biological process	-
CASQ1	844	calsequestrin 1 (fast-twitch, skeletal muscle)	sarcoplasmic reticulum	Cellular component	-
POLG	5428	polymerase (DNA directed), gamma	protein binding	Molecular function	16263719
SELP	6403	selectin P (granule membrane protein 140kDa, antigen CD62)	sialic acid binding	Molecular function	7680663
NFATC4	4776	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	regulation of synaptic plasticity	Biological process	-
IARS2	55699	isoleucyl-tRNA synthetase 2, mitochondrial	cytoplasm	Cellular component	-
CD69	969	CD69 molecule	integral component of plasma membrane	Cellular component	8340758
CRTAP	10491	cartilage associated protein	macromolecular complex	Cellular component	-
SMAD5	4090	SMAD family member 5	nucleus	Cellular component	19018011
CNTNAP1	8506	contactin associated protein 1	integral component of membrane	Cellular component	-
PPP1R15A	23645	protein phosphatase 1, regulatory subunit 15A	negative regulation of phosphoprotein phosphatase activity	Biological process	11564868
MEIS3	56917	Meis homeobox 3	negative regulation of apoptotic signaling pathway	Biological process	-
RRAGA	10670	Ras-related GTP binding A	cytoplasm	Cellular component	11073942
FBXO2	26232	F-box protein 2	endoplasmic reticulum	Cellular component	-
SSC5D	284297	scavenger receptor cysteine rich family, 5 domains	membrane	Cellular component	-
USP20	10868	ubiquitin specific peptidase 20	perinuclear region of cytoplasm	Cellular component	-
IL4I1	259307	interleukin 4 induced 1	oxidation-reduction process	Biological process	-
CTSV	1515	cathepsin V	neuron projection	Cellular component	-
MAPK9	5601	mitogen-activated protein kinase 9	TRIF-dependent toll-like receptor signaling pathway	Biological process	-
RGS12	6002	regulator of G-protein signaling 12	nucleus	Cellular component	-
WISP3	8838	WNT1 inducible signaling pathway protein 3	growth factor activity	Molecular function	-
POLR2F	5435	polymerase (RNA) II (DNA directed) polypeptide F	mRNA splicing, via spliceosome	Biological process	-
PKD2	5311	polycystic kidney disease 2 (autosomal dominant)	metanephric smooth muscle tissue development	Biological process	11891195
NR4A3	8013	nuclear receptor subfamily 4, group A, member 3	zinc ion binding	Molecular function	-
NAA50	80218	N(alpha)-acetyltransferase 50, NatE catalytic subunit	peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor	Molecular function	19744929
NDUFS3	4722	NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)	mitochondrial inner membrane	Cellular component	-
MRPL41	64975	mitochondrial ribosomal protein L41	ribonucleoprotein complex	Cellular component	16024796
CUL5	8065	cullin 5	protein binding	Molecular function	12504025
LHX3	8022	LIM homeobox 3	motor neuron axon guidance	Biological process	-
B4GALT3	8703	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3	Golgi membrane	Cellular component	-
SERPINE2	5270	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2	extrinsic component of external side of plasma membrane	Cellular component	19855083
NF1	4763	neurofibromin 1	cerebral cortex development	Biological process	-
IL10	3586	interleukin 10	response to inactivity	Biological process	-
POR	5447	P450 (cytochrome) oxidoreductase	endoplasmic reticulum membrane	Cellular component	-
AGMAT	79814	agmatine ureohydrolase (agmatinase)	cellular nitrogen compound metabolic process	Biological process	-
RBFOX3	146713	RNA binding protein, fox-1 homolog (C. elegans) 3	nucleotide binding	Molecular function	-
SRD5A2	6716	steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)	phthalate metabolic process	Biological process	-
SLITRK6	84189	SLIT and NTRK-like family, member 6	cell surface	Cellular component	23543054
DPYSL5	56896	dihydropyrimidinase-like 5	neuronal cell body	Cellular component	-
SCN11A	11280	sodium channel, voltage gated, type XI alpha subunit	neuronal action potential	Biological process	-
COTL1	23406	coactosin-like F-actin binding protein 1	nuclear membrane	Cellular component	-
HEY2	23493	hes-related family bHLH transcription factor with YRPW motif 2	tricuspid valve morphogenesis	Biological process	-
ARSF	416	arylsulfatase F	extracellular exosome	Cellular component	19056867
SCGB2A1	4246	secretoglobin, family 2A, member 1	androgen receptor signaling pathway	Biological process	16020486
BCL6	604	B-cell CLL/lymphoma 6	negative regulation of Notch signaling pathway	Biological process	-
AMBP	259	alpha-1-microglobulin/bikunin precursor	protein catabolic process	Biological process	-
SCNN1G	6340	sodium channel, non voltage gated 1 gamma subunit	external side of plasma membrane	Cellular component	-
CBX4	8535	chromobox homolog 4	SUMO binding	Molecular function	20176810
EML1	2009	echinoderm microtubule associated protein like 1	calcium ion binding	Molecular function	9226380
NR1H4	9971	nuclear receptor subfamily 1, group H, member 4	regulation of cholesterol metabolic process	Biological process	21757002
RGN	9104	regucalcin	regulation of calcium-mediated signaling	Biological process	-
SAP30L	79685	SAP30-like	regulation of gene expression, epigenetic	Biological process	-
LEF1	51176	lymphoid enhancer-binding factor 1	positive regulation of granulocyte differentiation	Biological process	23001182
ZFHX3	463	zinc finger homeobox 3	nucleus	Cellular component	1719379
GXYLT1	283464	glucoside xylosyltransferase 1	glycosaminoglycan metabolic process	Biological process	-
CYP2W1	54905	cytochrome P450, family 2, subfamily W, polypeptide 1	cell surface	Cellular component	20805301
PLK3	1263	polo-like kinase 3	regulation of cell division	Biological process	20951827
PIK3C3	5289	phosphatidylinositol 3-kinase, catalytic subunit type 3	innate immune response	Biological process	-
CHRNE	1145	cholinergic receptor, nicotinic, epsilon (muscle)	cation transmembrane transporter activity	Molecular function	8872460
CGGBP1	8545	CGG triplet repeat binding protein 1	RNA polymerase II regulatory region sequence-specific DNA binding	Molecular function	10692448
RPS4X	6191	ribosomal protein S4, X-linked	viral transcription	Biological process	-
PDLIM3	27295	PDZ and LIM domain 3	structural constituent of muscle	Molecular function	-
FGF2	2247	fibroblast growth factor 2 (basic)	positive regulation of transcription from RNA polymerase II promoter	Biological process	18059339
RAB4B	53916	RAB4B, member RAS oncogene family	intracellular protein transport	Biological process	-
BACH1	571	BTB and CNC homology 1, basic leucine zipper transcription factor 1	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	-
TBC1D1	23216	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1	cytosol	Cellular component	-
FGFR2	2263	fibroblast growth factor receptor 2	prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis	Biological process	-
CCR2	729230	chemokine (C-C motif) receptor 2	positive regulation of astrocyte chemotaxis	Biological process	12271471
OR4M1	441670	olfactory receptor, family 4, subfamily M, member 1	detection of chemical stimulus involved in sensory perception	Biological process	-
PRDM14	63978	PR domain containing 14	germ-line stem cell maintenance	Biological process	-
PRKAA2	5563	protein kinase, AMP-activated, alpha 2 catalytic subunit	lipid biosynthetic process	Biological process	-
ACVR1	90	activin A receptor, type I	positive regulation of determination of dorsal identity	Biological process	19506109
NRP1	8829	neuropilin 1	patterning of blood vessels	Biological process	-
ATP6V1E1	529	ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1	protein binding	Molecular function	11399750
MXD4	10608	MAX dimerization protein 4	nucleus	Cellular component	-
NOXRED1	122945	NADP-dependent oxidoreductase domain containing 1	pyrroline-5-carboxylate reductase activity	Molecular function	-
FGFBP3	143282	fibroblast growth factor binding protein 3	extracellular region	Cellular component	18669637
KCNH3	23416	potassium channel, voltage gated eag related subfamily H, member 3	signal transduction by protein phosphorylation	Biological process	-
GSX2	170825	GS homeobox 2	positive regulation of Notch signaling pathway	Biological process	-
BIN1	274	bridging integrator 1	axon	Cellular component	23399914
MYO7A	4647	myosin VIIA	cytoplasm	Cellular component	-
THRA	7067	thyroid hormone receptor, alpha	female courtship behavior	Biological process	-
TGFBI	7045	transforming growth factor, beta-induced, 68kDa	collagen binding	Molecular function	19478074
BATF2	116071	basic leucine zipper transcription factor, ATF-like 2	sequence-specific DNA binding	Molecular function	-
PDIA4	9601	protein disulfide isomerase family A, member 4	chaperone-mediated protein folding	Biological process	-
FAM170A	340069	family with sequence similarity 170, member A	nucleus	Cellular component	-
FECH	2235	ferrochelatase	regulation of eIF2 alpha phosphorylation by heme	Biological process	-
LIX1	167410	Lix1 homolog (chicken)	autophagosome maturation	Biological process	-
SMAD1	4086	SMAD family member 1	midbrain development	Biological process	-
PSMB11	122706	proteasome (prosome, macropain) subunit, beta type, 11	innate immune response	Biological process	-
ZMAT5	55954	zinc finger, matrin-type 5	zinc ion binding	Molecular function	-
PRDX5	25824	peroxiredoxin 5	mitochondrial matrix	Cellular component	-
UNC79	57578	unc-79 homolog (C. elegans)	plasma membrane	Cellular component	-
CRBN	51185	cereblon	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological process	20223979
XBP1	7494	X-box binding protein 1	positive regulation of hepatocyte proliferation	Biological process	-
EPRS	2058	glutamyl-prolyl-tRNA synthetase	gene expression	Biological process	-
ZNF816	125893	zinc finger protein 816	DNA binding	Molecular function	-
Sep-04	5414	septin 4	cell division	Biological process	-
TARBP2	6895	TAR (HIV-1) RNA binding protein 2	regulation of translation	Biological process	-
BSG	682	basigin (Ok blood group)	cellular metabolic process	Biological process	-
KIF2C	11004	kinesin family member 2C	metabolic process	Biological process	9434124
INSR	3643	insulin receptor	activation of protein kinase B activity	Biological process	7556070
IFNA14	3448	interferon, alpha 14	T cell activation involved in immune response	Biological process	-
NPTN	27020	neuroplastin	long-term synaptic potentiation	Biological process	-
GATA2	2624	GATA binding protein 2	negative regulation of macrophage differentiation	Biological process	-
TAAR1	134864	trace amine associated receptor 1	trace-amine receptor activity	Molecular function	-
TMC3	342125	transmembrane channel-like 3	ion transport	Biological process	-
SVIP	258010	small VCP/p97-interacting protein	negative regulation of ER-associated ubiquitin-dependent protein catabolic process	Biological process	17872946
ITGAV	3685	integrin, alpha V	cell-substrate adhesion	Biological process	19933311
AQP2	359	aquaporin 2 (collecting duct)	cellular response to water deprivation	Biological process	-
EIF2AK1	27102	eukaryotic translation initiation factor 2-alpha kinase 1	response to stress	Biological process	11036079
OPA1	4976	optic atrophy 1 (autosomal dominant)	apoptotic process	Biological process	-
TP73	7161	tumor protein p73	cell cycle arrest	Biological process	-
AIG1	51390	androgen-induced 1	protein binding	Molecular function	21988832
TTK	7272	TTK protein kinase	protein serine/threonine kinase activity	Molecular function	-
MAPK11	5600	mitogen-activated protein kinase 11	toll-like receptor 10 signaling pathway	Biological process	-
HNRNPH2	3188	heterogeneous nuclear ribonucleoprotein H2 (H')	membrane	Cellular component	19946888
ASAP1	50807	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	GTPase activator activity	Molecular function	-
SPAST	6683	spastin	positive regulation of cytokinesis	Biological process	18997780
ADAM9	8754	ADAM metallopeptidase domain 9	collagen catabolic process	Biological process	-
INHA	3623	inhibin, alpha	cell cycle arrest	Biological process	12456957
PLCL1	5334	phospholipase C-like 1	inositol 1,4,5 trisphosphate binding	Molecular function	-
CDC42EP3	10602	CDC42 effector protein (Rho GTPase binding) 3	GTPase activator activity	Molecular function	-
SRCAP	10847	Snf2-related CREBBP activator protein	histone acetylation	Biological process	10347196
JUN	3725	jun proto-oncogene	toll-like receptor 4 signaling pathway	Biological process	-
KLRG1	10219	killer cell lectin-like receptor subfamily G, member 1	receptor activity	Molecular function	9765598
ETHE1	23474	ethylmalonic encephalopathy 1	sulfur amino acid catabolic process	Biological process	-
KMT2D	8085	lysine (K)-specific methyltransferase 2D	histone H3-K4 methylation	Biological process	-
DES	1674	desmin	cytoskeletal protein binding	Molecular function	11309420
GHITM	27069	growth hormone inducible transmembrane protein	protein binding	Molecular function	21903422
ONECUT2	9480	one cut homeobox 2	endocrine pancreas development	Biological process	-
CREBZF	58487	CREB/ATF bZIP transcription factor	protein binding	Molecular function	10871379
CAMK4	814	calcium/calmodulin-dependent protein kinase IV	ATP binding	Molecular function	-
ARRB2	409	arrestin, beta 2	nucleus	Cellular component	16820410
MYO1G	64005	myosin IG	motor activity	Molecular function	-
PSMA7	5688	proteasome (prosome, macropain) subunit, alpha type, 7	regulation of cellular amino acid metabolic process	Biological process	-
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	beta-catenin destruction complex	Cellular component	16188939
SMAD4	4089	SMAD family member 4	somatic stem cell maintenance	Biological process	-
CAV3	859	caveolin 3	intercalated disc	Cellular component	-
ARG1	383	arginase 1	cytosol	Cellular component	-
RPL9	6133	ribosomal protein L9	viral transcription	Biological process	-
ATF4	468	activating transcription factor 4	PERK-mediated unfolded protein response	Biological process	22013210
MT3	4504	metallothionein 3	cellular response to cadmium ion	Biological process	16387743
PRKCA	5578	protein kinase C, alpha	positive regulation of ERK1 and ERK2 cascade	Biological process	-
LMOD2	442721	leiomodin 2 (cardiac)	myofibril assembly	Biological process	-
HRG	3273	histidine-rich glycoprotein	defense response to fungus	Biological process	18797515
MYD88	4615	myeloid differentiation primary response 88	toll-like receptor 2 signaling pathway	Biological process	-
CDA	978	cytidine deaminase	pyrimidine nucleobase metabolic process	Biological process	-
SEMA6A	57556	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	organ morphogenesis	Biological process	10993894
MCF2L	23263	MCF.2 cell line derived transforming sequence-like	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
CORIN	10699	corin, serine peptidase	regulation of renal sodium excretion	Biological process	-
LIF	3976	leukemia inhibitory factor	leukemia inhibitory factor signaling pathway	Biological process	12643274
HDAC11	79885	histone deacetylase 11	nucleus	Cellular component	11948178
RANBP2	5903	RAN binding protein 2	protein sumoylation	Biological process	-
IL2	3558	interleukin 2	natural killer cell activation	Biological process	8476561
AKAP17A	8227	A kinase (PRKA) anchor protein 17A	spliceosomal complex	Cellular component	-
IKBKB	3551	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	protein heterodimerization activity	Molecular function	23091055
NR2E1	7101	nuclear receptor subfamily 2, group E, member 1	cerebral cortex neuron differentiation	Biological process	-
TUSC3	7991	tumor suppressor candidate 3	plasma membrane	Cellular component	-
BYSL	705	bystin-like	female pregnancy	Biological process	9560222
UGT3A2	167127	UDP glycosyltransferase 3 family, polypeptide A2	intracellular membrane-bounded organelle	Cellular component	-
IRS1	3667	insulin receptor substrate 1	signal transducer activity	Molecular function	-
MTERF1	7978	mitochondrial transcription termination factor 1	termination of mitochondrial transcription	Biological process	-
CYB561D2	11068	cytochrome b561 family, member D2	integral component of membrane	Cellular component	-
TPI1	7167	triosephosphate isomerase 1	protein binding	Molecular function	20849852
WNT11	7481	wingless-type MMTV integration site family, member 11	outflow tract morphogenesis	Biological process	-
FOXP2	93986	forkhead box P2	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	-
TNFSF14	8740	tumor necrosis factor (ligand) superfamily, member 14	cytokine activity	Molecular function	-
PDGFD	80310	platelet derived growth factor D	growth factor activity	Molecular function	-
ATOX1	475	antioxidant 1 copper chaperone	copper ion transport	Biological process	15670166
SMYD2	56950	SET and MYND domain containing 2	RNA polymerase II core binding	Molecular function	-
LEPR	3953	leptin receptor	identical protein binding	Molecular function	20347812
HTR1B	3351	5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled	cytoplasm	Cellular component	-
ARHGEF38	54848	Rho guanine nucleotide exchange factor (GEF) 38	positive regulation of GTPase activity	Biological process	-
EDN1	1906	endothelin 1	cell surface receptor signaling pathway	Biological process	1713452
ALDH1A3	220	aldehyde dehydrogenase 1 family, member A3	extracellular exosome	Cellular component	23533145
BRAF	673	B-Raf proto-oncogene, serine/threonine kinase	identical protein binding	Molecular function	16858395
GPAA1	8733	glycosylphosphatidylinositol anchor attachment 1	tubulin binding	Molecular function	12052837
SLC25A27	9481	solute carrier family 25, member 27	small molecule metabolic process	Biological process	-
GJB1	2705	gap junction protein, beta 1, 32kDa	nervous system development	Biological process	8266101
GDF11	10220	growth differentiation factor 11	regulation of apoptotic process	Biological process	-
NCOA2	10499	nuclear receptor coactivator 2	regulation of glucose metabolic process	Biological process	-
E2F2	1870	E2F transcription factor 2	transcription factor binding	Molecular function	16360038
PIAS4	51588	protein inhibitor of activated STAT, 4	nucleus	Cellular component	9724754
NOS3	4846	nitric oxide synthase 3 (endothelial cell)	vascular endothelial growth factor receptor signaling pathway	Biological process	-
VCL	7414	vinculin	actin binding	Molecular function	7816144
PIK3R4	30849	phosphoinositide-3-kinase, regulatory subunit 4	phosphatidylinositol 3-kinase complex, class III, type I	Cellular component	-
DGKH	160851	diacylglycerol kinase, eta	plasma membrane	Cellular component	-
DDOST	1650	dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)	protein binding	Molecular function	21903422
EDA2R	60401	ectodysplasin A2 receptor	ectodermal cell differentiation	Biological process	12270937
AANAT	15	aralkylamine N-acetyltransferase	response to insulin	Biological process	-
IRF6	3664	interferon regulatory factor 6	protein binding	Molecular function	16049006
SYT2	127833	synaptotagmin II	calcium ion binding	Molecular function	-
CRYGS	1427	crystallin, gamma S	morphogenesis of an epithelium	Biological process	-
SNRPG	6637	small nuclear ribonucleoprotein polypeptide G	SMN-Sm protein complex	Cellular component	18984161
SIN3A	25942	SIN3 transcription regulator family member A	protein deacetylase activity	Molecular function	22783022
TMED10	10972	transmembrane emp24-like trafficking protein 10 (yeast)	extracellular exosome	Cellular component	23376485
BAG2	9532	BCL2-associated athanogene 2	identical protein binding	Molecular function	22365833
CYP2F1	1572	cytochrome P450, family 2, subfamily F, polypeptide 1	exogenous drug catabolic process	Biological process	-
AACS	65985	acetoacetyl-CoA synthetase	response to ethanol	Biological process	-
ATF2	1386	activating transcription factor 2	toll-like receptor TLR1:TLR2 signaling pathway	Biological process	-
ATP5S	27109	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)	mitochondrial inner membrane	Cellular component	-
HMGN5	79366	high mobility group nucleosome binding domain 5	intracellular membrane-bounded organelle	Cellular component	-
MSTN	2660	myostatin	positive regulation of transcription, DNA-templated	Biological process	14517293
XKRY2	353515	XK, Kell blood group complex subunit-related, Y-linked 2	integral component of membrane	Cellular component	-
OR1M1	125963	olfactory receptor, family 1, subfamily M, member 1	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
PRKAB1	5564	protein kinase, AMP-activated, beta 1 non-catalytic subunit	protein phosphorylation	Biological process	17028174
PTK2B	2185	protein tyrosine kinase 2 beta	positive regulation of actin filament polymerization	Biological process	18765415
EIF2S1	1965	eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa	membrane	Cellular component	19946888
BAP1	8314	BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)	protein deubiquitination	Biological process	18757409
CDCA8	55143	cell division cycle associated 8	cell division	Biological process	-
FEV	54738	FEV (ETS oncogene family)	transcription corepressor activity	Molecular function	9121764
NDNL2	56160	necdin-like 2	cellular protein metabolic process	Biological process	-
TSSK4	283629	testis-specific serine kinase 4	multicellular organismal development	Biological process	-
NAP1L2	4674	nucleosome assembly protein 1-like 2	nucleosome assembly	Biological process	-
NGF	4803	nerve growth factor (beta polypeptide)	response to radiation	Biological process	-
OR51B4	79339	olfactory receptor, family 51, subfamily B, member 4	olfactory receptor activity	Molecular function	11121057
UBE2N	7334	ubiquitin-conjugating enzyme E2N	protein K63-linked ubiquitination	Biological process	16307917
PXDN	7837	peroxidasin	interleukin-1 receptor antagonist activity	Molecular function	11103812
EIF4E1B	253314	eukaryotic translation initiation factor 4E family member 1B	translation initiation factor activity	Molecular function	-
ALB	213	albumin	bile acid and bile salt transport	Biological process	-
MORC3	23515	MORC family CW-type zinc finger 3	post-embryonic development	Biological process	-
IL6	3569	interleukin 6	negative regulation of chemokine biosynthetic process	Biological process	-
HOXB8	3218	homeobox B8	regulation of transcription, DNA-templated	Biological process	-
RYR2	6262	ryanodine receptor 2 (cardiac)	regulation of AV node cell action potential	Biological process	17875969
UMODL1	89766	uromodulin-like 1	regulation of gene expression	Biological process	-
HES3	390992	hes family bHLH transcription factor 3	midbrain development	Biological process	-
LGI3	203190	leucine-rich repeat LGI family, member 3	extracellular region	Cellular component	-
EIF5A	1984	eukaryotic translation initiation factor 5A	RNA binding	Molecular function	15303967
SMN1	6606	survival of motor neuron 1, telomeric	Z disc	Cellular component	-
PRIMPOL	201973	primase and polymerase (DNA-directed)	protein binding	Molecular function	24126761
GTF3C5	9328	general transcription factor IIIC, polypeptide 5, 63kDa	skeletal muscle cell differentiation	Biological process	-
RNF212	285498	ring finger protein 212	zinc ion binding	Molecular function	-
ARHGAP1	392	Rho GTPase activating protein 1	cytosol	Cellular component	-
STARD10	10809	StAR-related lipid transfer (START) domain containing 10	membrane	Cellular component	-
TENM1	10178	teneurin transmembrane protein 1	protein heterodimerization activity	Molecular function	-
RTN4	57142	reticulon 4	nuclear envelope	Cellular component	11126360
RPS16	6217	ribosomal protein S16	translational initiation	Biological process	-
PAK4	10298	p21 protein (Cdc42/Rac)-activated kinase 4	cell proliferation	Biological process	20070256
CDC42EP3	10602	CDC42 effector protein (Rho GTPase binding) 3	signal transduction	Biological process	11035016
IPO5	3843	importin 5	protein binding	Molecular function	10799599
CRH	1392	corticotropin releasing hormone	neuropeptide hormone activity	Molecular function	7867564
EPHB3	2049	EPH receptor B3	angiogenesis	Biological process	-
LRRK2	120892	leucine-rich repeat kinase 2	activation of MAPK activity	Biological process	21857923
DTYMK	1841	deoxythymidylate kinase (thymidylate kinase)	response to cadmium ion	Biological process	-
EPO	2056	erythropoietin	embryo implantation	Biological process	-
PPARGC1A	10891	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	positive regulation of mitochondrial DNA metabolic process	Biological process	-
JPH4	84502	junctophilin 4	junctional sarcoplasmic reticulum membrane	Cellular component	19095005
PTEN	5728	phosphatase and tensin homolog	positive regulation of excitatory postsynaptic membrane potential	Biological process	-
LIAS	11019	lipoic acid synthetase	neural tube closure	Biological process	-
GRB14	2888	growth factor receptor-bound protein 14	endosome membrane	Cellular component	-
PTPRC	5788	protein tyrosine phosphatase, receptor type, C	positive regulation of protein kinase activity	Biological process	15275963
NR2F2	7026	nuclear receptor subfamily 2, group F, member 2	protein homodimerization activity	Molecular function	18798693
NAT16	375607	N-acetyltransferase 16 (GCN5-related, putative)	peptide alpha-N-acetyltransferase activity	Molecular function	-
GABARAPL2	11345	GABA(A) receptor-associated protein-like 2	GABA receptor binding	Molecular function	11414770
TRUB2	26995	TruB pseudouridine (psi) synthase family member 2	poly(A) RNA binding	Molecular function	22658674
ABCC2	1244	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	transmembrane transport	Biological process	-
CALY	50632	calcyon neuron-specific vesicular protein	clathrin coat assembly	Biological process	16595675
OR4M2	390538	olfactory receptor, family 4, subfamily M, member 2	detection of chemical stimulus involved in sensory perception	Biological process	-
AKAP6	9472	A kinase (PRKA) anchor protein 6	junctional sarcoplasmic reticulum membrane	Cellular component	-
BHLHE22	27319	basic helix-loop-helix family, member e22	transcription from RNA polymerase II promoter	Biological process	-
SLC31A1	1317	solute carrier family 31 (copper transporter), member 1	recycling endosome	Cellular component	-
MAP3K11	4296	mitogen-activated protein kinase kinase kinase 11	protein binding	Molecular function	20890305
FAS	355	Fas cell surface death receptor	regulation of myeloid cell differentiation	Biological process	-
HK1	3098	hexokinase 1	mannokinase activity	Molecular function	-
AGER	177	advanced glycosylation end product-specific receptor	plasma membrane	Cellular component	-
ARRB1	408	arrestin, beta 1	coated pit	Cellular component	-
YLPM1	56252	YLP motif containing 1	protein binding	Molecular function	21078624
BMI1	648	BMI1 proto-oncogene, polycomb ring finger	zinc ion binding	Molecular function	16714294
GRM8	2918	glutamate receptor, metabotropic 8	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway	Biological process	9473604
RASL10B	91608	RAS-like, family 10, member B	plasma membrane	Cellular component	-
OR4D5	219875	olfactory receptor, family 4, subfamily D, member 5	transmembrane signaling receptor activity	Molecular function	-
CRIPT	9419	cysteine-rich PDZ-binding protein	postsynaptic density	Cellular component	-
KLK3	354	kallikrein-related peptidase 3	proteolysis	Biological process	-
CALCRL	10203	calcitonin receptor-like	calcitonin gene-related peptide receptor activity	Molecular function	-
WNT2B	7482	wingless-type MMTV integration site family, member 2B	Wnt signaling pathway	Biological process	15135146
TINAGL1	64129	tubulointerstitial nephritis antigen-like 1	extracellular exosome	Cellular component	19199708
AP1G1	164	adaptor-related protein complex 1, gamma 1 subunit	antigen processing and presentation of exogenous peptide antigen via MHC class II	Biological process	-
FZD9	8326	frizzled class receptor 9	plasma membrane	Cellular component	19038973
ASPH	444	aspartate beta-hydroxylase	structural constituent of muscle	Molecular function	11007777
FGF10	2255	fibroblast growth factor 10	positive regulation of hair follicle cell proliferation	Biological process	16086254
COL4A4	1286	collagen, type IV, alpha 4	collagen catabolic process	Biological process	-
FICD	11153	FIC domain containing	ATP binding	Molecular function	-
SPARC	6678	secreted protein, acidic, cysteine-rich (osteonectin)	positive regulation of endothelial cell migration	Biological process	12867428
RAB19	401409	RAB19, member RAS oncogene family	extracellular exosome	Cellular component	19056867
GATAD1	57798	GATA zinc finger domain containing 1	regulation of transcription, DNA-templated	Biological process	-
WNK2	65268	WNK lysine deficient protein kinase 2	regulation of ion homeostasis	Biological process	21733846
UNC13A	23025	unc-13 homolog A (C. elegans)	neurotransmitter secretion	Biological process	-
CD79A	973	CD79a molecule, immunoglobulin-associated alpha	integral component of membrane	Cellular component	-
SIRT2	22933	sirtuin 2	NAD+ binding	Molecular function	11427894
RPS6KA5	9252	ribosomal protein S6 kinase, 90kDa, polypeptide 5	protein serine/threonine kinase activity	Molecular function	12773393
JUP	3728	junction plakoglobin	cell-cell junction organization	Biological process	-
HIRA	7290	histone cell cycle regulator	transcription corepressor activity	Molecular function	9731536
PARP1	142	poly (ADP-ribose) polymerase 1	nuclear envelope	Cellular component	9518481
ING2	3622	inhibitor of growth family, member 2	male germ-line stem cell asymmetric division	Biological process	21124965
RNF130	55819	ring finger protein 130	ligase activity	Molecular function	-
UIMC1	51720	ubiquitin interaction motif containing 1	nucleus	Cellular component	-
KIF2C	11004	kinesin family member 2C	cell division	Biological process	-
KCNH5	27133	potassium channel, voltage gated eag related subfamily H, member 5	phosphorelay signal transduction system	Biological process	-
NUP88	4927	nucleoporin 88kDa	small molecule metabolic process	Biological process	-
ARHGAP6	395	Rho GTPase activating protein 6	small GTPase mediated signal transduction	Biological process	-
ABCB8	11194	ATP-binding cassette, sub-family B (MDR/TAP), member 8	integral component of membrane	Cellular component	-
TIGD7	91151	tigger transposable element derived 7	protein binding	Molecular function	25416956
CD34	947	CD34 molecule	negative regulation of blood coagulation	Biological process	17505307
TACSTD2	4070	tumor-associated calcium signal transducer 2	cytosol	Cellular component	10192395
GATB	5188	glutamyl-tRNA(Gln) amidotransferase, subunit B	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity	Molecular function	19805282
ANO6	196527	anoctamin 6	blood coagulation	Biological process	-
MAD2L1	4085	MAD2 mitotic arrest deficient-like 1 (yeast)	nucleus	Cellular component	18981471
OCRL	4952	oculocerebrorenal syndrome of Lowe	regulation of GTPase activity	Biological process	12915445
TSPO	706	translocator protein (18kDa)	steroid metabolic process	Biological process	16822554
ACTN2	88	actinin, alpha 2	ion channel binding	Molecular function	10812072
SCAMP1	9522	secretory carrier membrane protein 1	protein domain specific binding	Molecular function	-
HBB	3043	hemoglobin, beta	oxygen binding	Molecular function	11747442
RPS27A	6233	ribosomal protein S27a	necroptotic process	Biological process	-
TTN	7273	titin	regulation of catalytic activity	Biological process	9804419
IGKV3D-20	28874	immunoglobulin kappa variable 3D-20	immune response	Biological process	5027703
RAD23A	5886	RAD23 homolog A (S. cerevisiae)	ubiquitin-specific protease binding	Molecular function	22970133
RPS28	6234	ribosomal protein S28	cytosol	Cellular component	-
ACSBG2	81616	acyl-CoA synthetase bubblegum family member 2	multicellular organismal development	Biological process	-
CXCL9	4283	chemokine (C-X-C motif) ligand 9	chemokine activity	Molecular function	12782716
HSPA8	3312	heat shock 70kDa protein 8	membrane organization	Biological process	-
RAB11A	8766	RAB11A, member RAS oncogene family	intracellular protein transport	Biological process	-
C10orf2	56652	chromosome 10 open reading frame 2	ATP binding	Molecular function	-
CLPSL2	389383	colipase-like 2	digestion	Biological process	-
TNS3	64759	tensin 3	protein binding	Molecular function	16273093
UBE2I	7329	ubiquitin-conjugating enzyme E2I	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological process	-
MBNL3	55796	muscleblind-like splicing regulator 3	regulation of RNA splicing	Biological process	15257297
UBB	7314	ubiquitin B	positive regulation of NF-kappaB transcription factor activity	Biological process	-
FER	2241	fer (fps/fes related) tyrosine kinase	positive regulation of cell migration	Biological process	19738202
SMAD7	4092	SMAD family member 7	negative regulation of transcription from RNA polymerase II promoter	Biological process	17438144
RANBP2	5903	RAN binding protein 2	protein folding	Biological process	-
PHF8	23133	PHD finger protein 8	nucleolus	Cellular component	20208542
ALDH7A1	501	aldehyde dehydrogenase 7 family, member A1	betaine-aldehyde dehydrogenase activity	Molecular function	-
UPP1	7378	uridine phosphorylase 1	cellular response to glucose starvation	Biological process	-
BCL2L11	10018	BCL2-like 11 (apoptosis facilitator)	odontogenesis of dentin-containing tooth	Biological process	-
PDGFB	5155	platelet-derived growth factor beta polypeptide	reactive oxygen species metabolic process	Biological process	17942966
PDE5A	8654	phosphodiesterase 5A, cGMP-specific	positive regulation of oocyte development	Biological process	-
OR8G2	26492	olfactory receptor, family 8, subfamily G, member 2	G-protein coupled receptor activity	Molecular function	-
SOS2	6655	son of sevenless homolog 2 (Drosophila)	positive regulation of apoptotic process	Biological process	-
OR11H7	390441	olfactory receptor, family 11, subfamily H, member 7 (gene/pseudogene)	plasma membrane	Cellular component	-
MAFK	7975	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K	regulation of transcription, DNA-templated	Biological process	-
VAMP5	10791	vesicle-associated membrane protein 5	SNAP receptor activity	Molecular function	-
NODAL	4838	nodal growth differentiation factor	inhibition of neuroepithelial cell differentiation	Biological process	-
CRTC1	23373	CREB regulated transcription coactivator 1	transcription, DNA-templated	Biological process	-
MCM5	4174	minichromosome maintenance complex component 5	MCM complex	Cellular component	17296731
RBL1	5933	retinoblastoma-like 1	protein binding	Molecular function	1331501
SCN3B	55800	sodium channel, voltage gated, type III beta subunit	membrane depolarization during cardiac muscle cell action potential	Biological process	21051419
NAP1L2	4674	nucleosome assembly protein 1-like 2	protein binding	Molecular function	18985028
CHRNA3	1136	cholinergic receptor, nicotinic, alpha 3 (neuronal)	signal transduction	Biological process	8906617
CLYBL	171425	citrate lyase beta like	metabolic process	Biological process	-
CLCN1	1180	chloride channel, voltage-sensitive 1	integral component of plasma membrane	Cellular component	9122265
OR4F16	81399	olfactory receptor, family 4, subfamily F, member 16	transmembrane signaling receptor activity	Molecular function	-
NME4	4833	NME/NM23 nucleoside diphosphate kinase 4	lipid transport	Biological process	-
WIPI2	26100	WD repeat domain, phosphoinositide interacting 2	autophagosome assembly	Biological process	20505359
VDAC1	7416	voltage-dependent anion channel 1	voltage-gated anion channel activity	Molecular function	8420959
ARHGEF9	23229	Cdc42 guanine nucleotide exchange factor (GEF) 9	regulation of small GTPase mediated signal transduction	Biological process	-
NR0B1	190	nuclear receptor subfamily 0, group B, member 1	gonad development	Biological process	7990953
OR52E2	119678	olfactory receptor, family 52, subfamily E, member 2	G-protein coupled receptor activity	Molecular function	-
MAPKAPK5	8550	mitogen-activated protein kinase-activated protein kinase 5	MAPK cascade	Biological process	9628874
SMAD6	4091	SMAD family member 6	identical protein binding	Molecular function	9436979
CTCF	10664	CCCTC-binding factor (zinc finger protein)	regulation of gene expression, epigenetic	Biological process	16815976
ABCB8	11194	ATP-binding cassette, sub-family B (MDR/TAP), member 8	mitochondrion	Cellular component	-
DAB2IP	153090	DAB2 interacting protein	negative regulation of catenin import into nucleus	Biological process	-
ADIPOQ	9370	adiponectin, C1Q and collagen domain containing	negative regulation of low-density lipoprotein particle receptor biosynthetic process	Biological process	11222466
UGT8	7368	UDP glycosyltransferase 8	integral component of membrane	Cellular component	-
MUC13	56667	mucin 13, cell surface associated	protein O-linked glycosylation	Biological process	-
OSR1	130497	odd-skipped related transciption factor 1	metanephric mesenchyme morphogenesis	Biological process	-
RNF34	80196	ring finger protein 34, E3 ubiquitin protein ligase	nucleus	Cellular component	22064484
ANGPTL3	27329	angiopoietin-like 3	integrin binding	Molecular function	11877390
EBP	10682	emopamil binding protein (sterol isomerase)	transmembrane signaling receptor activity	Molecular function	7706302
HMG20A	10363	high mobility group 20A	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
EHD1	10938	EH-domain containing 1	cholesterol homeostasis	Biological process	-
APOA4	337	apolipoprotein A-IV	triglyceride homeostasis	Biological process	-
HOXB1	3211	homeobox B1	anatomical structure formation involved in morphogenesis	Biological process	-
LRRK2	120892	leucine-rich repeat kinase 2	autophagy	Biological process	-
SSX9	280660	synovial sarcoma, X breakpoint 9	nucleus	Cellular component	-
TRIM11	81559	tripartite motif containing 11	zinc ion binding	Molecular function	-
S100A13	6284	S100 calcium binding protein A13	fibroblast growth factor binding	Molecular function	11432880
NTRK3	4916	neurotrophic tyrosine kinase, receptor, type 3	neuron fate specification	Biological process	-
IGF2R	3482	insulin-like growth factor 2 receptor	liver development	Biological process	-
CCR5	1234	chemokine (C-C motif) receptor 5 (gene/pseudogene)	chemokine-mediated signaling pathway	Biological process	10201901
MTOR	2475	mechanistic target of rapamycin (serine/threonine kinase)	protein binding	Molecular function	10089303
HTT	3064	huntingtin	striatum development	Biological process	-
SLC22A12	116085	solute carrier family 22 (organic anion/urate transporter), member 12	extracellular exosome	Cellular component	19056867
HACE1	57531	HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1	Golgi organization	Biological process	21988917
KCNA5	3741	potassium channel, voltage gated shaker related subfamily A, member 5	endoplasmic reticulum	Cellular component	-
VAMP4	8674	vesicle-associated membrane protein 4	SNARE complex	Cellular component	-
ITGB3	3690	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	positive regulation of peptidyl-tyrosine phosphorylation	Biological process	10022831
CHMP4C	92421	charged multivesicular body protein 4C	protein binding	Molecular function	14505570
CENPA	1058	centromere protein A	protein localization to chromosome, centromeric region	Biological process	11682612
CALM3	808	calmodulin 3 (phosphorylase kinase, delta)	cytosol	Cellular component	-
TCF23	150921	transcription factor 23	nucleus	Cellular component	-
USH2A	7399	Usher syndrome 2A (autosomal recessive, mild)	photoreceptor cell maintenance	Biological process	10090909
CUL7	9820	cullin 7	protein binding	Molecular function	17298945
FIS1	51024	fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)	positive regulation of mitochondrial calcium ion concentration	Biological process	21183955
TGM4	7047	transglutaminase 4	metal ion binding	Molecular function	-
PJA2	9867	praja ring finger 2, E3 ubiquitin protein ligase	regulation of protein kinase A signaling	Biological process	21423175
ATRX	546	alpha thalassemia/mental retardation syndrome X-linked	chromo shadow domain binding	Molecular function	15882967
MYO1C	4641	myosin IC	innate immune response	Biological process	-
PAX6	5080	paired box 6	response to wounding	Biological process	17982423
PIK3C3	5289	phosphatidylinositol 3-kinase, catalytic subunit type 3	peroxisome degradation	Biological process	-
FBLN1	2192	fibulin 1	embryo implantation	Biological process	-
PAK6	56924	p21 protein (Cdc42/Rac)-activated kinase 6	regulation of transcription, DNA-templated	Biological process	20070256
SHROOM2	357	shroom family member 2	actin binding	Molecular function	-
ITGA4	3676	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	heart development	Biological process	-
USP26	83844	ubiquitin specific peptidase 26	protein deubiquitination	Biological process	20501646
C1S	716	complement component 1, s subcomponent	calcium ion binding	Molecular function	-
ALS2CL	259173	ALS2 C-terminal like	endosome organization	Biological process	17239822
ZBTB26	57684	zinc finger and BTB domain containing 26	transcription, DNA-templated	Biological process	-
RIPK3	11035	receptor-interacting serine-threonine kinase 3	toll-like receptor signaling pathway	Biological process	-
BMP10	27302	bone morphogenetic protein 10	Z disc	Cellular component	17921333
BACH1	571	BTB and CNC homology 1, basic leucine zipper transcription factor 1	DNA repair	Biological process	11301010
D2HGDH	728294	D-2-hydroxyglutarate dehydrogenase	small molecule metabolic process	Biological process	-
GPR89B	51463	G protein-coupled receptor 89B	protein transport	Biological process	-
DLG3	1741	discs, large homolog 3 (Drosophila)	ionotropic glutamate receptor complex	Cellular component	-
SPHK1	8877	sphingosine kinase 1	small molecule metabolic process	Biological process	-
ALKBH8	91801	alkB, alkylation repair homolog 8 (E. coli)	tRNA binding	Molecular function	22065580
XCL1	6375	chemokine (C motif) ligand 1	negative regulation of T-helper 1 cell activation	Biological process	10887101
NGFR	4804	nerve growth factor receptor	membrane protein intracellular domain proteolysis	Biological process	-
GULP1	51454	GULP, engulfment adaptor PTB domain containing 1	apoptotic process	Biological process	-
STEAP3	55240	STEAP family member 3, metalloreductase	endosome membrane	Cellular component	-
S100A6	6277	S100 calcium binding protein A6	ruffle	Cellular component	10913138
RAB10	10890	RAB10, member RAS oncogene family	protein localization to plasma membrane	Biological process	-
EXOSC4	54512	exosome component 4	protein binding	Molecular function	11719186
FZR1	51343	fizzy/cell division cycle 20 related 1 (Drosophila)	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	Biological process	-
DPAGT1	1798	dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)	dolichol biosynthetic process	Biological process	8179616
ENTPD3	956	ectonucleoside triphosphate diphosphohydrolase 3	nucleoside triphosphate catabolic process	Biological process	-
GPC3	2719	glypican 3	mesonephric duct morphogenesis	Biological process	-
STAB1	23166	stabilin 1	low-density lipoprotein receptor activity	Molecular function	12077138
NUP98	4928	nucleoporin 98kDa	protein binding	Molecular function	15146057
TNIP2	79155	TNFAIP3 interacting protein 2	protein binding	Molecular function	12595760
PTPN14	5784	protein tyrosine phosphatase, non-receptor type 14	protein tyrosine phosphatase activity	Molecular function	22525271
COL6A5	256076	collagen, type VI, alpha 5	extracellular matrix organization	Biological process	-
MAP2K6	5608	mitogen-activated protein kinase kinase 6	cardiac muscle contraction	Biological process	-
CELF3	11189	CUGBP, Elav-like family member 3	RNA binding	Molecular function	17725984
KEAP1	9817	kelch-like ECH-associated protein 1	cytosol	Cellular component	17015834
ZNF420	147923	zinc finger protein 420	sequence-specific DNA binding transcription factor activity	Molecular function	-
FECH	2235	ferrochelatase	response to arsenic-containing substance	Biological process	-
GSTM5	2949	glutathione S-transferase mu 5	cytosol	Cellular component	-
TWF2	11344	twinfilin actin-binding protein 2	regulation of microvillus length	Biological process	19955359
TMOD1	7111	tropomodulin 1	tropomyosin binding	Molecular function	-
SOX2	6657	SRY (sex determining region Y)-box 2	nuclear transcription factor complex	Cellular component	-
ADAMTS8	11095	ADAM metallopeptidase with thrombospondin type 1 motif, 8	metallopeptidase activity	Molecular function	10438512
CYBB	1536	cytochrome b-245, beta polypeptide	innate immune response	Biological process	12716910
RNF20	56254	ring finger protein 20, E3 ubiquitin protein ligase	nucleus	Cellular component	16307923
ECT2	1894	epithelial cell transforming 2	cellular response to ionizing radiation	Biological process	21373644
ADGRL1	22859	adhesion G protein-coupled receptor L1	integral component of membrane	Cellular component	-
THOC5	8563	THO complex 5	nucleoplasm	Cellular component	-
MTUS2	23281	microtubule associated tumor suppressor candidate 2	nucleus	Cellular component	19806667
APP	351	amyloid beta (A4) precursor protein	plasma membrane	Cellular component	12805363
DUSP1	1843	dual specificity phosphatase 1	protein binding	Molecular function	10617468
FEV	54738	FEV (ETS oncogene family)	regulation of transcription from RNA polymerase II promoter	Biological process	-
BDH1	622	3-hydroxybutyrate dehydrogenase, type 1	response to cadmium ion	Biological process	-
CASP14	23581	caspase 14, apoptosis-related cysteine peptidase	intrinsic apoptotic signaling pathway in response to DNA damage	Biological process	-
SMARCA4	6597	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	transcription corepressor activity	Molecular function	18487222
POLR2L	5441	polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa	DNA-directed RNA polymerase I complex	Cellular component	-
PSMB7	5695	proteasome (prosome, macropain) subunit, beta type, 7	stimulatory C-type lectin receptor signaling pathway	Biological process	-
PRSS12	8492	protease, serine, 12 (neurotrypsin, motopsin)	cytoplasmic vesicle	Cellular component	-
ZBTB26	57684	zinc finger and BTB domain containing 26	molecular_function	Molecular function	-
COL21A1	81578	collagen, type XXI, alpha 1	extracellular matrix organization	Biological process	-
ADCY1	107	adenylate cyclase 1 (brain)	neurotrophin TRK receptor signaling pathway	Biological process	-
PTGER1	5731	prostaglandin E receptor 1 (subtype EP1), 42kDa	response to lipopolysaccharide	Biological process	-
MSH2	4436	mutS homolog 2	MutLalpha complex binding	Molecular function	16403449
GDPD3	79153	glycerophosphodiester phosphodiesterase domain containing 3	lipid metabolic process	Biological process	-
CYP1A2	1544	cytochrome P450, family 1, subfamily A, polypeptide 2	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	Molecular function	2813353
APOA1	335	apolipoprotein A-I	positive regulation of lipoprotein lipase activity	Biological process	-
TPMT	7172	thiopurine S-methyltransferase	small molecule metabolic process	Biological process	-
KCNK17	89822	potassium channel, two pore domain subfamily K, member 17	stabilization of membrane potential	Biological process	-
SMAD4	4089	SMAD family member 4	transcription initiation from RNA polymerase II promoter	Biological process	-
HES5	388585	hes family bHLH transcription factor 5	chondrocyte differentiation	Biological process	-
TFRC	7037	transferrin receptor	extracellular region	Cellular component	1871153
ZNF662	389114	zinc finger protein 662	metal ion binding	Molecular function	-
IGHV2-70	28454	immunoglobulin heavy variable 2-70	innate immune response	Biological process	-
OBP2A	29991	odorant binding protein 2A	extracellular region	Cellular component	-
STK32A	202374	serine/threonine kinase 32A	protein phosphorylation	Biological process	-
CLTC	1213	clathrin, heavy chain (Hc)	poly(A) RNA binding	Molecular function	22681889
SUPT6H	6830	suppressor of Ty 6 homolog (S. cerevisiae)	regulation of mRNA export from nucleus	Biological process	-
CKLF	51192	chemokine-like factor	extracellular space	Cellular component	-
XRCC5	7520	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	telomeric DNA binding	Molecular function	10535943
ADAM10	102	ADAM metallopeptidase domain 10	extracellular matrix disassembly	Biological process	-
AQP9	366	aquaporin 9	amine transport	Biological process	9733774
ZNF516	9658	zinc finger protein 516	brown fat cell differentiation	Biological process	-
ATP5B	506	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide	transmembrane transporter activity	Molecular function	12110673
SUPV3L1	6832	suppressor of var1, 3-like 1 (S. cerevisiae)	DNA recombination	Biological process	17961633
TNKS	8658	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase	nuclear membrane	Cellular component	11454873
RNF212	285498	ring finger protein 212	chiasma assembly	Biological process	-
L3MBTL4	91133	l(3)mbt-like 4 (Drosophila)	sequence-specific DNA binding transcription factor activity	Molecular function	-
POLR2F	5435	polymerase (RNA) II (DNA directed) polypeptide F	positive regulation of viral transcription	Biological process	-
HIST1H2BF	8343	histone cluster 1, H2bf	nuclear nucleosome	Cellular component	-
LBP	3929	lipopolysaccharide binding protein	positive regulation of interleukin-8 production	Biological process	8409400
EEA1	8411	early endosome antigen 1	extrinsic component of plasma membrane	Cellular component	7768953
STAT5A	6776	signal transducer and activator of transcription 5A	T cell homeostasis	Biological process	-
NTRK3	4916	neurotrophic tyrosine kinase, receptor, type 3	positive regulation of peptidyl-serine phosphorylation	Biological process	23027130
RIPK3	11035	receptor-interacting serine-threonine kinase 3	positive regulation of NF-kappaB transcription factor activity	Biological process	21931591
KCNK2	3776	potassium channel, two pore domain subfamily K, member 2	regulation of ion transmembrane transport	Biological process	-
IFT52	51098	intraflagellar transport 52	intraciliary transport	Biological process	-
S1PR1	1901	sphingosine-1-phosphate receptor 1	intrinsic component of plasma membrane	Cellular component	22344443
CRY2	1408	cryptochrome circadian clock 2	transcription, DNA-templated	Biological process	-
LAMB1	3912	laminin, beta 1	neuronal-glial interaction involved in cerebral cortex radial glia guided migration	Biological process	23472759
CALCOCO2	10241	calcium binding and coiled-coil domain 2	perinuclear region of cytoplasm	Cellular component	9230084
RAG1	5896	recombination activating gene 1	acid-amino acid ligase activity	Molecular function	-
NSUN2	54888	NOP2/Sun RNA methyltransferase family, member 2	tRNA methylation	Biological process	17071714
MCAM	4162	melanoma cell adhesion molecule	vascular wound healing	Biological process	20354148
ARMS2	387715	age-related maculopathy susceptibility 2	retina homeostasis	Biological process	18511946
TRIM37	4591	tripartite motif containing 37	ubiquitin protein ligase activity	Molecular function	25470042
SORBS2	8470	sorbin and SH3 domain containing 2	actin filament organization	Biological process	-
STAT5A	6776	signal transducer and activator of transcription 5A	negative regulation of erythrocyte differentiation	Biological process	-
ZNF521	25925	zinc finger protein 521	DNA binding	Molecular function	-
SP1	6667	Sp1 transcription factor	histone deacetylase binding	Molecular function	17827154
COL6A3	1293	collagen, type VI, alpha 3	extracellular region	Cellular component	-
HELLS	3070	helicase, lymphoid-specific	protein binding	Molecular function	22157815
ANG	283	angiogenin, ribonuclease, RNase A family, 5	protein homodimerization activity	Molecular function	25372031
RIPK1	8737	receptor (TNFRSF)-interacting serine-threonine kinase 1	receptor complex	Cellular component	8612133
HIST2H3D	653604	histone cluster 2, H3d	protein binding	Molecular function	20580717
IGF1	3479	insulin-like growth factor 1 (somatomedin C)	positive regulation of smooth muscle cell proliferation	Biological process	10766744
PCSK6	5046	proprotein convertase subtilisin/kexin type 6	endopeptidase activity	Molecular function	9242664
MRPL50	54534	mitochondrial ribosomal protein L50	mitochondrial translational elongation	Biological process	-
RPL32	6161	ribosomal protein L32	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Biological process	-
BOD1	91272	biorientation of chromosomes in cell division 1	cell division	Biological process	-
ADAM8	101	ADAM metallopeptidase domain 8	positive regulation of neutrophil extravasation	Biological process	17548643
DLG2	1740	discs, large homolog 2 (Drosophila)	nucleotide phosphorylation	Biological process	8755482
POLR2H	5437	polymerase (RNA) II (DNA directed) polypeptide H	nucleus	Cellular component	-
RGS14	10636	regulator of G-protein signaling 14	GTPase activating protein binding	Molecular function	-
RCBTB1	55213	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1	chromatin modification	Biological process	-
SERBP1	26135	SERPINE1 mRNA binding protein 1	poly(A) RNA binding	Molecular function	22658674
ADD2	119	adducin 2 (beta)	actin filament binding	Molecular function	7642559
ECT2	1894	epithelial cell transforming 2	cellular response to hydrogen peroxide	Biological process	21373644
TMEM41A	90407	transmembrane protein 41A	protein binding	Molecular function	25416956
MYO1B	4430	myosin IB	myosin complex	Cellular component	-
CABLES1	91768	Cdk5 and Abl enzyme substrate 1	cytosol	Cellular component	17101133
FNDC3A	22862	fibronectin type III domain containing 3A	cytosol	Cellular component	-
KAT2A	2648	K(lysine) acetyltransferase 2A	transcription factor TFTC complex	Cellular component	10373431
PSMD8	5714	proteasome (prosome, macropain) 26S subunit, non-ATPase, 8	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	Biological process	-
GCGR	2642	glucagon receptor	glucose homeostasis	Biological process	-
FOXP1	27086	forkhead box P1	regulation of interleukin-1 beta secretion	Biological process	18799727
MYRIP	25924	myosin VIIA and Rab interacting protein	dense core granule	Cellular component	-
SRP72	6731	signal recognition particle 72kDa	7S RNA binding	Molecular function	-
SRRM4	84530	serine/arginine repetitive matrix 4	cell differentiation	Biological process	-
HDC	3067	histidine decarboxylase	pyridoxal phosphate binding	Molecular function	-
MED12L	116931	mediator complex subunit 12-like	beta-catenin binding	Molecular function	-
PARK2	5071	parkin RBR E3 ubiquitin protein ligase	negative regulation of oxidative stress-induced cell death	Biological process	24252804
PRKG1	5592	protein kinase, cGMP-dependent, type I	actin cytoskeleton organization	Biological process	10851246
RAPGEF2	9693	Rap guanine nucleotide exchange factor (GEF) 2	PDZ domain binding	Molecular function	10548487
SLC2A1	6513	solute carrier family 2 (facilitated glucose transporter), member 1	extracellular exosome	Cellular component	20458337
UBTF	7343	upstream binding transcription factor, RNA polymerase I	positive regulation of transcription from RNA polymerase I promoter	Biological process	-
ACE	1636	angiotensin I converting enzyme	blood vessel remodeling	Biological process	1668266
UGT1A1	54658	UDP glucuronosyltransferase 1 family, polypeptide A1	heme catabolic process	Biological process	-
IMP4	92856	IMP4, U3 small nucleolar ribonucleoprotein	rRNA processing	Biological process	12655004
KHDRBS1	10657	KH domain containing, RNA binding, signal transduction associated 1	cell cycle arrest	Biological process	9013542
PPP1R12A	4659	protein phosphatase 1, regulatory subunit 12A	positive regulation of transcription from RNA polymerase II promoter	Biological process	19245366
TEAD2	8463	TEA domain family member 2	embryonic heart tube morphogenesis	Biological process	-
HMGB2	3148	high mobility group box 2	cellular component disassembly involved in execution phase of apoptosis	Biological process	-
ARRDC3	57561	arrestin domain containing 3	negative regulation of multicellular organismal metabolic process	Biological process	-
OR1L4	254973	olfactory receptor, family 1, subfamily L, member 4	olfactory receptor activity	Molecular function	-
RAB7A	7879	RAB7A, member RAS oncogene family	GTP binding	Molecular function	18272684
FGD3	89846	FYVE, RhoGEF and PH domain containing 3	cytosol	Cellular component	-
SMAD7	4092	SMAD family member 7	metal ion binding	Molecular function	-
PIK3C2A	5286	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha	extracellular exosome	Cellular component	19056867
LRRC47	57470	leucine rich repeat containing 47	phenylalanine-tRNA ligase complex	Cellular component	-
CHKA	1119	choline kinase alpha	signal transduction	Biological process	10363580
STK25	10494	serine/threonine kinase 25	positive regulation of axonogenesis	Biological process	-
ANTXR1	84168	anthrax toxin receptor 1	actin cytoskeleton reorganization	Biological process	16762926
GABRG2	2566	gamma-aminobutyric acid (GABA) A receptor, gamma 2	post-embryonic development	Biological process	-
POU5F1	5460	POU class 5 homeobox 1	regulation of transcription, DNA-templated	Biological process	16153702
SEC31A	22872	SEC31 homolog A (S. cerevisiae)	ER to Golgi vesicle-mediated transport	Biological process	-
COL18A1	80781	collagen, type XVIII, alpha 1	extracellular region	Cellular component	-
CHST4	10164	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4	sulfur compound metabolic process	Biological process	10330415
MR1	3140	major histocompatibility complex, class I-related	innate immune response	Biological process	-
ZNF619	285267	zinc finger protein 619	metal ion binding	Molecular function	-
NOP14	8602	NOP14 nucleolar protein	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Biological process	-
SPTBN5	51332	spectrin, beta, non-erythrocytic 5	dynein intermediate chain binding	Molecular function	23704327
VAV3	10451	vav 3 guanine nucleotide exchange factor	small GTPase mediated signal transduction	Biological process	-
FLAD1	80308	flavin adenine dinucleotide synthetase 1	FMN adenylyltransferase activity	Molecular function	-
WIPF3	644150	WAS/WASL interacting protein family, member 3	cytosol	Cellular component	-
JAG1	182	jagged 1	regulation of cell migration	Biological process	11549580
ANK2	287	ankyrin 2, neuronal	regulation of cardiac muscle contraction	Biological process	15178757
PCSK1	5122	proprotein convertase subtilisin/kexin type 1	extracellular space	Cellular component	8397508
SLC7A7	9056	solute carrier family 7 (amino acid transporter light chain, y+L system), member 7	cellular amino acid metabolic process	Biological process	9829974
PHLDA2	7262	pleckstrin homology-like domain, family A, member 2	membrane	Cellular component	-
CLU	1191	clusterin	positive regulation of nitric oxide biosynthetic process	Biological process	15857407
IFI16	3428	interferon, gamma-inducible protein 16	negative regulation of innate immune response	Biological process	22046441
FOXP2	93986	forkhead box P2	skeletal muscle tissue development	Biological process	-
C6orf47	57827	chromosome 6 open reading frame 47	cytoplasm	Cellular component	-
ELK1	2002	ELK1, member of ETS oncogene family	core promoter binding	Molecular function	-
RPS27A	6233	ribosomal protein S27a	transcription, DNA-templated	Biological process	-
FIGF	2277	c-fos induced growth factor (vascular endothelial growth factor D)	platelet alpha granule lumen	Cellular component	-
CDK5R1	8851	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	axon	Cellular component	-
LIG4	3981	ligase IV, DNA, ATP-dependent	somatic stem cell maintenance	Biological process	-
CCL28	56477	chemokine (C-C motif) ligand 28	cell chemotaxis	Biological process	18308860
SUPV3L1	6832	suppressor of var1, 3-like 1 (S. cerevisiae)	mitochondrial mRNA surveillance	Biological process	19864255
RAN	5901	RAN, member RAS oncogene family	pre-miRNA export from nucleus	Biological process	14681208
CTRB2	440387	chymotrypsinogen B2	proteolysis	Biological process	-
TMEM254	80195	transmembrane protein 254	integral component of membrane	Cellular component	-
AKR1C1	1645	aldo-keto reductase family 1, member C1	digestion	Biological process	8486699
FGF19	9965	fibroblast growth factor 19	positive regulation of protein phosphorylation	Biological process	17627937
AFG3L2	10939	AFG3-like AAA ATPase 2	mitochondrial inner membrane	Cellular component	-
FABP1	2168	fatty acid binding protein 1, liver	small molecule metabolic process	Biological process	-
NSFL1C	55968	NSFL1 (p97) cofactor (p47)	protein binding	Molecular function	16275660
GAS6	2621	growth arrest-specific 6	receptor agonist activity	Molecular function	15184064
GNAT3	346562	guanine nucleotide binding protein, alpha transducing 3	response to nicotine	Biological process	-
HTR4	3360	5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled	integral component of plasma membrane	Cellular component	-
ETS1	2113	v-ets avian erythroblastosis virus E26 oncogene homolog 1	positive regulation of transcription, DNA-templated	Biological process	10698492
PARP16	54956	poly (ADP-ribose) polymerase family, member 16	endoplasmic reticulum membrane	Cellular component	-
TLR9	54106	toll-like receptor 9	positive regulation of JNK cascade	Biological process	17128265
CASP8	841	caspase 8, apoptosis-related cysteine peptidase	response to estradiol	Biological process	-
PLAGL2	5326	pleiomorphic adenoma gene-like 2	post-embryonic development	Biological process	-
SPHK1	8877	sphingosine kinase 1	axon	Cellular component	-
PARD3	56288	par-3 family cell polarity regulator	endomembrane system	Cellular component	-
FAT4	79633	FAT atypical cadherin 4	extracellular exosome	Cellular component	23376485
TYK2	7297	tyrosine kinase 2	peptidyl-tyrosine autophosphorylation	Biological process	-
GPR12	2835	G protein-coupled receptor 12	phosphatidylcholine binding	Molecular function	-
CRH	1392	corticotropin releasing hormone	regulation of serotonin secretion	Biological process	-
ATP2B2	491	ATPase, Ca++ transporting, plasma membrane 2	auditory receptor cell stereocilium organization	Biological process	-
C9orf69	90120	chromosome 9 open reading frame 69	cytoplasm	Cellular component	21667337
PIK3CB	5291	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta	adaptive immune response	Biological process	-
PGM5	5239	phosphoglucomutase 5	cytosol	Cellular component	-
PLEKHF1	79156	pleckstrin homology domain containing, family F (with FYVE domain) member 1	lysosome	Cellular component	22115783
ADGRL4	64123	adhesion G protein-coupled receptor L4	plasma membrane	Cellular component	-
SFTPD	6441	surfactant protein D	extracellular space	Cellular component	-
SPINK5	11005	serine peptidase inhibitor, Kazal type 5	perinuclear region of cytoplasm	Cellular component	15680911
STAB1	23166	stabilin 1	defense response to bacterium	Biological process	12077138
PCDH8	5100	protocadherin 8	cell junction	Cellular component	-
TMC1	117531	transmembrane channel-like 1	detection of mechanical stimulus involved in sensory perception of sound	Biological process	-
LACRT	90070	lacritin	calcineurin-NFAT signaling cascade	Biological process	16923831
TDRD9	122402	tudor domain containing 9	piP-body	Cellular component	-
FBXO25	26260	F-box protein 25	SCF ubiquitin ligase complex	Cellular component	-
FGF10	2255	fibroblast growth factor 10	positive regulation of lymphocyte proliferation	Biological process	19152659
GPC4	2239	glypican 4	extracellular space	Cellular component	-
IGHG3	3502	immunoglobulin heavy constant gamma 3 (G3m marker)	extracellular exosome	Cellular component	23533145
PAK4	10298	p21 protein (Cdc42/Rac)-activated kinase 4	movement of cell or subcellular component	Biological process	9822598
BAZ2B	29994	bromodomain adjacent to zinc finger domain, 2B	protein binding	Molecular function	10662543
ARRDC4	91947	arrestin domain containing 4	positive regulation of ubiquitin-protein transferase activity	Biological process	23236378
HLA-C	3107	major histocompatibility complex, class I, C	TAP binding	Molecular function	8617941
ZMYND15	84225	zinc finger, MYND-type containing 15	negative regulation of transcription, DNA-templated	Biological process	-
CYP2C8	1558	cytochrome P450, family 2, subfamily C, polypeptide 8	small molecule metabolic process	Biological process	-
PLAGL1	5325	pleiomorphic adenoma gene-like 1	cell cycle arrest	Biological process	9184226
NEUROD6	63974	neuronal differentiation 6	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
TFCP2L1	29842	transcription factor CP2-like 1	steroid biosynthetic process	Biological process	10644752
SIX1	6495	SIX homeobox 1	generation of neurons	Biological process	-
USF1	7391	upstream transcription factor 1	protein binding	Molecular function	19303849
DDB2	1643	damage-specific DNA binding protein 2, 48kDa	DNA repair	Biological process	-
C2CD5	9847	C2 calcium-dependent domain containing 5	protein localization to plasma membrane	Biological process	-
MLX	6945	MLX, MAX dimerization protein	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	10918583
TPCN2	219931	two pore segment channel 2	voltage-gated calcium channel activity	Molecular function	-
CSF3	1440	colony stimulating factor 3 (granulocyte)	positive regulation of myeloid cell differentiation	Biological process	-
EDN1	1906	endothelin 1	response to prostaglandin F	Biological process	-
SRGAP2	23380	SLIT-ROBO Rho GTPase activating protein 2	neuron projection morphogenesis	Biological process	-
LRRC59	55379	leucine rich repeat containing 59	poly(A) RNA binding	Molecular function	22658674
VPS4A	27183	vacuolar protein sorting 4 homolog A (S. cerevisiae)	regulation of protein localization	Biological process	18005716
CA9	768	carbonic anhydrase IX	secretion	Biological process	-
CTGF	1490	connective tissue growth factor	cell-matrix adhesion	Biological process	-
DUSP4	1846	dual specificity phosphatase 4	nucleoplasm	Cellular component	-
COX19	90639	COX19 cytochrome c oxidase assembly factor	aerobic respiration	Biological process	-
FABP2	2169	fatty acid binding protein 2, intestinal	transporter activity	Molecular function	-
MED24	9862	mediator complex subunit 24	histone acetylation	Biological process	-
GRIN2A	2903	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	endoplasmic reticulum	Cellular component	-
ADAM8	101	ADAM metallopeptidase domain 8	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex	Cellular component	15220135
RAB21	23011	RAB21, member RAS oncogene family	positive regulation of early endosome to late endosome transport	Biological process	15561770
NMBR	4829	neuromedin B receptor	bombesin receptor activity	Molecular function	-
TBX18	9096	T-box 18	transcription regulatory region sequence-specific DNA binding	Molecular function	-
GZMM	3004	granzyme M (lymphocyte met-ase 1)	extracellular region	Cellular component	-
KIF18A	81930	kinesin family member 18A	cytosol	Cellular component	-
CYP1B1	1545	cytochrome P450, family 1, subfamily B, polypeptide 1	positive regulation of vascular endothelial growth factor production	Biological process	-
SLC52A2	79581	solute carrier family 52 (riboflavin transporter), member 2	riboflavin transport	Biological process	20463145
GRIN1	2902	glutamate receptor, ionotropic, N-methyl D-aspartate 1	synaptic cleft	Cellular component	-
MAFB	9935	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B	protein binding	Molecular function	10698492
PTGER3	5733	prostaglandin E receptor 3 (subtype EP3)	positive regulation of cytosolic calcium ion concentration	Biological process	-
APOC1	341	apolipoprotein C-I	plasma lipoprotein particle remodeling	Biological process	10978346
FKBP1A	2280	FK506 binding protein 1A, 12kDa	ventricular cardiac muscle tissue morphogenesis	Biological process	-
STAM2	10254	signal transducing adaptor molecule (SH3 domain and ITAM motif) 2	epidermal growth factor receptor signaling pathway	Biological process	-
GLMP	112770	glycosylated lysosomal membrane protein	ligand-dependent nuclear receptor transcription coactivator activity	Molecular function	18021396
CECR2	27443	cat eye syndrome chromosome region, candidate 2	neural fold formation	Biological process	-
OR6C65	403282	olfactory receptor, family 6, subfamily C, member 65	integral component of membrane	Cellular component	-
CYP26A1	1592	cytochrome P450, family 26, subfamily A, polypeptide 1	anterior/posterior pattern specification	Biological process	-
HIST1H4I	8294	histone cluster 1, H4i	negative regulation of megakaryocyte differentiation	Biological process	18474616
SDIM1	100505705	stress responsive DNAJB4 interacting membrane protein 1	cellular response to stress	Biological process	21255413
HSF1	3297	heat shock transcription factor 1	regulation of cellular response to heat	Biological process	-
DLG1	1739	discs, large homolog 1 (Drosophila)	smooth muscle tissue development	Biological process	-
RPS15	6209	ribosomal protein S15	translational initiation	Biological process	-
ZP2	7783	zona pellucida glycoprotein 2 (sperm receptor)	endoplasmic reticulum	Cellular component	-
DBH	1621	dopamine beta-hydroxylase (dopamine beta-monooxygenase)	response to pain	Biological process	-
HARBI1	283254	harbinger transposase derived 1	centrosome	Cellular component	-
MKL2	57496	MKL/myocardin-like 2	positive regulation of striated muscle tissue development	Biological process	14565952
AGTPBP1	23287	ATP/GTP binding protein 1	mitochondrion organization	Biological process	-
SUPT3H	8464	suppressor of Ty 3 homolog (S. cerevisiae)	DNA binding	Molecular function	-
BUB3	9184	BUB3 mitotic checkpoint protein	nucleoplasm	Cellular component	-
DUSP6	1848	dual specificity phosphatase 6	response to nitrosative stress	Biological process	10846176
IGKV3D-20	28874	immunoglobulin kappa variable 3D-20	regulation of immune response	Biological process	-
KDM3B	51780	lysine (K)-specific demethylase 3B	chromatin modification	Biological process	-
SERHL2	253190	serine hydrolase-like 2	metabolic process	Biological process	-
SLC9A2	6549	solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2	ion transport	Biological process	-
RBBP4	5928	retinoblastoma binding protein 4	negative regulation of gene expression, epigenetic	Biological process	-
SYT3	84258	synaptotagmin III	calcium-dependent phospholipid binding	Molecular function	12526776
SOX17	64321	SRY (sex determining region Y)-box 17	sequence-specific DNA binding	Molecular function	-
EPM2A	7957	epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)	protein tyrosine phosphatase activity	Molecular function	9931343
CDKN1A	1026	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	negative regulation of G1/S transition of mitotic cell cycle	Biological process	21628527
VAMP2	6844	vesicle-associated membrane protein 2 (synaptobrevin 2)	membrane fusion	Biological process	-
ANXA1	301	annexin A1	single-stranded DNA binding	Molecular function	-
BTF3	689	basic transcription factor 3	nucleus	Cellular component	-
SOCS2	8835	suppressor of cytokine signaling 2	protein binding	Molecular function	11781573
TERF1	7013	telomeric repeat binding factor (NIMA-interacting) 1	microtubule binding	Molecular function	11943150
RIMKLB	57494	ribosomal modification protein rimK-like family member B	ATP binding	Molecular function	-
HIST1H4A	8359	histone cluster 1, H4a	telomere maintenance	Biological process	-
STK16	8576	serine/threonine kinase 16	ATP binding	Molecular function	-
PBX1	5087	pre-B-cell leukemia homeobox 1	sex differentiation	Biological process	-
FGF8	2253	fibroblast growth factor 8 (androgen-induced)	neuroepithelial cell differentiation	Biological process	17309880
IGF1	3479	insulin-like growth factor 1 (somatomedin C)	positive regulation of DNA replication	Biological process	-
TKTL1	8277	transketolase-like 1	transketolase activity	Molecular function	-
ZNF221	7638	zinc finger protein 221	regulation of transcription, DNA-templated	Biological process	-
SH3BP4	23677	SH3-domain binding protein 4	Ras GTPase binding	Molecular function	22575674
SCOC	60592	short coiled-coil protein	protein binding	Molecular function	20195357
MAPK11	5600	mitogen-activated protein kinase 11	activation of MAPK activity	Biological process	-
SLC35B4	84912	solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4	UDP-xylose transmembrane transporter activity	Molecular function	15911612
HACE1	57531	HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1	transcription, DNA-templated	Biological process	-
CATSPERG	57828	catsper channel auxiliary subunit gamma	multicellular organism reproduction	Biological process	-
CENPC	1060	centromere protein C	kinetochore	Cellular component	21529714
STX4	6810	syntaxin 4	positive regulation of cell adhesion	Biological process	21720706
BAG4	9530	BCL2-associated athanogene 4	cytosol	Cellular component	-
MFN2	9927	mitofusin 2	mitochondrion	Cellular component	11181170
CDC6	990	cell division cycle 6	regulation of transcription involved in G1/S transition of mitotic cell cycle	Biological process	-
CPA5	93979	carboxypeptidase A5	metallocarboxypeptidase activity	Molecular function	-
PLSCR1	5359	phospholipid scramblase 1	positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity	Biological process	17567603
NES	10763	nestin	intermediate filament	Cellular component	9917366
AKR1C1	1645	aldo-keto reductase family 1, member C1	response to organophosphorus	Biological process	16079077
SP3	6670	Sp3 transcription factor	embryonic process involved in female pregnancy	Biological process	-
MYADM	91663	myeloid-associated differentiation marker	negative regulation of actin filament polymerization	Biological process	23264465
PIM1	5292	Pim-1 proto-oncogene, serine/threonine kinase	plasma membrane	Cellular component	-
LRCOL1	100507055	leucine rich colipase-like 1	extracellular region	Cellular component	-
HEY2	23493	hes-related family bHLH transcription factor with YRPW motif 2	histone deacetylase binding	Molecular function	12535671
CD276	80381	CD276 molecule	cell proliferation	Biological process	11224528
FGFR4	2264	fibroblast growth factor receptor 4	response to bile acid	Biological process	19085950
TGFBRAP1	9392	transforming growth factor, beta receptor associated protein 1	protein binding	Molecular function	11278302
BMI1	648	BMI1 proto-oncogene, polycomb ring finger	segment specification	Biological process	7715727
OR13C8	138802	olfactory receptor, family 13, subfamily C, member 8	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
ARSI	340075	arylsulfatase family, member I	sphingolipid metabolic process	Biological process	-
NF2	4771	neurofibromin 2 (merlin)	regulation of hippo signaling	Biological process	20159598
EXOSC6	118460	exosome component 6	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	Biological process	-
WARS	7453	tryptophanyl-tRNA synthetase	tryptophan-tRNA ligase activity	Molecular function	-
PARL	55486	presenilin associated, rhomboid-like	protein processing	Biological process	-
NR1D1	9572	nuclear receptor subfamily 1, group D, member 1	transcription regulatory region DNA binding	Molecular function	18511497
PIK3C3	5289	phosphatidylinositol 3-kinase, catalytic subunit type 3	1-phosphatidylinositol-3-kinase activity	Molecular function	20208530
GRIK3	2899	glutamate receptor, ionotropic, kainate 3	extracellular-glutamate-gated ion channel activity	Molecular function	-
NDFIP2	54602	Nedd4 family interacting protein 2	Golgi membrane	Cellular component	-
TFDP1	7027	transcription factor Dp-1	apoptotic process	Biological process	-
MYOG	4656	myogenin (myogenic factor 4)	RNA polymerase II regulatory region sequence-specific DNA binding	Molecular function	-
NFU1	27247	NFU1 iron-sulfur cluster scaffold	iron ion binding	Molecular function	12886008
EIF2B4	8890	eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa	myelination	Biological process	14566705
GABRE	2564	gamma-aminobutyric acid (GABA) A receptor, epsilon	extracellular ligand-gated ion channel activity	Molecular function	-
RPL37A	6168	ribosomal protein L37a	structural constituent of ribosome	Molecular function	12962325
SLC34A1	6569	solute carrier family 34 (type II sodium/phosphate cotransporter), member 1	positive regulation of phosphate transmembrane transport	Biological process	-
RAB29	8934	RAB29, member RAS oncogene family	GTP binding	Molecular function	-
NRL	4901	neural retina leucine zipper	DNA binding	Molecular function	1729696
NFU1	27247	NFU1 iron-sulfur cluster scaffold	cytosol	Cellular component	12886008
CBX8	57332	chromobox homolog 8	single-stranded RNA binding	Molecular function	-
KIF15	56992	kinesin family member 15	metabolic process	Biological process	10878014
ACVR1	90	activin A receptor, type I	cellular response to glucocorticoid stimulus	Biological process	-
TRAF6	7189	TNF receptor-associated factor 6, E3 ubiquitin protein ligase	thioesterase binding	Molecular function	11279055
BAG3	9531	BCL2-associated athanogene 3	negative regulation of striated muscle cell apoptotic process	Biological process	-
B3GNT4	79369	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4	galactosyltransferase activity	Molecular function	-
NARF	26502	nuclear prelamin A recognition factor	lamin binding	Molecular function	10514485
MSTN	2660	myostatin	cytoplasm	Cellular component	-
SPG7	6687	spastic paraplegia 7 (pure and complicated autosomal recessive)	mitochondrion organization	Biological process	-
PRRG3	79057	proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)	calcium ion binding	Molecular function	-
P2RY1	5028	purinergic receptor P2Y, G-protein coupled, 1	G-protein coupled purinergic nucleotide receptor signaling pathway	Biological process	-
ODF1	4956	outer dense fiber of sperm tails 1	outer dense fiber	Cellular component	-
MAP2K3	5606	mitogen-activated protein kinase kinase 3	protein tyrosine kinase activity	Molecular function	-
TCF4	6925	transcription factor 4	bHLH transcription factor binding	Molecular function	-
RAD52	5893	RAD52 homolog (S. cerevisiae)	DNA binding	Molecular function	19506022
CHST3	9469	carbohydrate (chondroitin 6) sulfotransferase 3	proteoglycan sulfotransferase activity	Molecular function	-
HSPA13	6782	heat shock protein 70kDa family, member 13	ATP binding	Molecular function	-
BIRC8	112401	baculoviral IAP repeat containing 8	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	Molecular function	-
MYOD1	4654	myogenic differentiation 1	histone H4 acetylation	Biological process	-
ADH5	128	alcohol dehydrogenase 5 (class III), chi polypeptide	nucleus	Cellular component	-
SRGAP2	23380	SLIT-ROBO Rho GTPase activating protein 2	negative regulation of cell death	Biological process	20810653
DNAJA3	9093	DnaJ (Hsp40) homolog, subfamily A, member 3	activation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	10411904
FBXL3	26224	F-box and leucine-rich repeat protein 3	protein binding	Molecular function	17463251
JAKMIP1	152789	janus kinase and microtubule interacting protein 1	ribonucleoprotein complex	Cellular component	14718537
MRPS14	63931	mitochondrial ribosomal protein S14	mitochondrial translational termination	Biological process	-
HIST1H2AI	8329	histone cluster 1, H2ai	extracellular exosome	Cellular component	20458337
BAX	581	BCL2-associated X protein	intrinsic apoptotic signaling pathway	Biological process	-
KIAA0101	9768	KIAA0101	response to UV	Biological process	23000965
COL4A3BP	10087	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein	signal transduction	Biological process	-
ENOX1	55068	ecto-NOX disulfide-thiol exchanger 1	oxidoreductase activity	Molecular function	-
SEMA3C	10512	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	outflow tract morphogenesis	Biological process	-
ADPRM	56985	ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent	CDP-glycerol diphosphatase activity	Molecular function	-
MAFA	389692	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A	sequence-specific DNA binding transcription factor activity	Molecular function	12368292
SNRK	54861	SNF related kinase	magnesium ion binding	Molecular function	12234663
FAR2	55711	fatty acyl CoA reductase 2	peroxisome	Cellular component	-
TPCN2	219931	two pore segment channel 2	ion transmembrane transport	Biological process	-
PARK2	5071	parkin RBR E3 ubiquitin protein ligase	Golgi apparatus	Cellular component	17097639
ACADM	34	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	identical protein binding	Molecular function	19224950
TP53	7157	tumor protein p53	cellular response to DNA damage stimulus	Biological process	14744935
EPB41L5	57669	erythrocyte membrane protein band 4.1 like 5	positive regulation of epithelial cell migration	Biological process	-
MYO9B	4650	myosin IXB	lamellipodium	Cellular component	-
PIAS1	8554	protein inhibitor of activated STAT, 1	nuclear speck	Cellular component	-
SKA1	220134	spindle and kinetochore associated complex subunit 1	cytosol	Cellular component	-
CHEK2	11200	checkpoint kinase 2	replicative senescence	Biological process	15149599
GPR179	440435	G protein-coupled receptor 179	G-protein coupled receptor activity	Molecular function	-
ANXA13	312	annexin A13	membrane raft	Cellular component	-
BMP4	652	bone morphogenetic protein 4	odontogenesis of dentin-containing tooth	Biological process	-
MAP4K4	9448	mitogen-activated protein kinase kinase kinase kinase 4	creatine kinase activity	Molecular function	23207904
PHKG2	5261	phosphorylase kinase, gamma 2 (testis)	phosphorylase kinase complex	Cellular component	10487978
SRP54	6729	signal recognition particle 54kDa	nuclear speck	Cellular component	-
GPX3	2878	glutathione peroxidase 3	extracellular exosome	Cellular component	19199708
STOM	2040	stomatin	endoplasmic reticulum	Cellular component	25262680
LONP1	9361	lon peptidase 1, mitochondrial	oxidation-dependent protein catabolic process	Biological process	12198491
CHKB	1120	choline kinase beta	ATP binding	Molecular function	-
KIRREL3	84623	kin of IRRE like 3 (Drosophila)	neuron projection morphogenesis	Biological process	-
CD1D	912	CD1d molecule	heterotypic cell-cell adhesion	Biological process	19124746
CST4	1472	cystatin S	cysteine-type endopeptidase inhibitor activity	Molecular function	3488317
FAS	355	Fas cell surface death receptor	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	Biological process	-
SLBP	7884	stem-loop binding protein	mRNA binding	Molecular function	16912046
PEX14	5195	peroxisomal biogenesis factor 14	protein complex	Cellular component	-
PSMC3	5702	proteasome (prosome, macropain) 26S subunit, ATPase, 3	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly	Biological process	-
NPDC1	56654	neural proliferation, differentiation and control, 1	integral component of membrane	Cellular component	-
OR2B6	26212	olfactory receptor, family 2, subfamily B, member 6	sensory perception of smell	Biological process	-
NANOS2	339345	nanos homolog 2 (Drosophila)	mRNA catabolic process	Biological process	-
PDZRN4	29951	PDZ domain containing ring finger 4	ubiquitin protein ligase activity	Molecular function	-
MEF2C	4208	myocyte enhancer factor 2C	histone deacetylase binding	Molecular function	-
TNFSF12	8742	tumor necrosis factor (ligand) superfamily, member 12	positive regulation of endothelial cell proliferation	Biological process	14961121
BHLHE41	79365	basic helix-loop-helix family, member e41	E-box binding	Molecular function	-
IDUA	3425	iduronidase, alpha-L-	chemical homeostasis	Biological process	-
IQGAP1	8826	IQ motif containing GTPase activating protein 1	platelet-derived growth factor receptor signaling pathway	Biological process	-
USH2A	7399	Usher syndrome 2A (autosomal recessive, mild)	periciliary membrane compartment	Cellular component	-
RGCC	28984	regulator of cell cycle	protein kinase binding	Molecular function	-
RBBP7	5931	retinoblastoma binding protein 7	negative regulation of cell growth	Biological process	9765217
TBX5	6910	T-box 5	ventricular septum development	Biological process	-
OR1E3	8389	olfactory receptor, family 1, subfamily E, member 3 (gene/pseudogene)	G-protein coupled receptor activity	Molecular function	-
SLC12A3	6559	solute carrier family 12 (sodium/chloride transporter), member 3	transmembrane transport	Biological process	-
SMG1	23049	SMG1 phosphatidylinositol 3-kinase-related kinase	gene expression	Biological process	-
HSPB1	3315	heat shock 27kDa protein 1	cytoplasm	Cellular component	16130169
NEDD4L	23327	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase	positive regulation of protein catabolic process	Biological process	-
UGT1A1	54658	UDP glucuronosyltransferase 1 family, polypeptide A1	estrogen metabolic process	Biological process	8780690
MSH2	4436	mutS homolog 2	nucleoplasm	Cellular component	-
OR2T5	401993	olfactory receptor, family 2, subfamily T, member 5	olfactory receptor activity	Molecular function	-
RPS26	6231	ribosomal protein S26	gene expression	Biological process	-
MTDH	92140	metadherin	positive regulation of protein kinase B signaling	Biological process	17704808
PSMD7	5713	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	small molecule metabolic process	Biological process	-
KIAA1109	84162	KIAA1109	integral component of membrane	Cellular component	-
TSPAN11	441631	tetraspanin 11	integral component of membrane	Cellular component	-
KRT7	3855	keratin 7, type II	intermediate filament	Cellular component	2415537
RPS5	6193	ribosomal protein S5	structural constituent of ribosome	Molecular function	15883184
IARS	3376	isoleucyl-tRNA synthetase	protein binding	Molecular function	10913161
MAPT	4137	microtubule-associated protein tau	microtubule cytoskeleton organization	Biological process	1057175
MYL4	4635	myosin, light chain 4, alkali; atrial, embryonic	cardiac muscle contraction	Biological process	14985854
ITGA1	3672	integrin, alpha 1	perikaryon	Cellular component	-
EGR1	1958	early growth response 1	response to electrical stimulus	Biological process	-
GRHL2	79977	grainyhead-like 2 (Drosophila)	protein binding	Molecular function	25416956
ARHGEF1	9138	Rho guanine nucleotide exchange factor (GEF) 1	cell proliferation	Biological process	8810315
CDK3	1018	cyclin-dependent kinase 3	G0 to G1 transition	Biological process	15084261
CAMK1	8536	calcium/calmodulin-dependent protein kinase I	positive regulation of protein export from nucleus	Biological process	23867755
GSG2	83903	germ cell associated 2 (haspin)	histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore	Biological process	23071153
ASGR1	432	asialoglycoprotein receptor 1	metal ion binding	Molecular function	-
STAU2	27067	staufen double-stranded RNA binding protein 2	endoplasmic reticulum	Cellular component	-
B3GNT3	10331	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3	integral component of plasma membrane	Cellular component	10072769
UBE2C	11065	ubiquitin-conjugating enzyme E2C	ubiquitin conjugating enzyme activity	Molecular function	12629039
ATXN3L	92552	ataxin 3-like	omega peptidase activity	Molecular function	-
EPB42	2038	erythrocyte membrane protein band 4.2	cortical cytoskeleton	Cellular component	-
TUBA1A	7846	tubulin, alpha 1a	protein folding	Biological process	-
TACR1	6869	tachykinin receptor 1	response to ozone	Biological process	-
PKD2L1	9033	polycystic kidney disease 2-like 1	potassium ion transmembrane transport	Biological process	10517637
HEYL	26508	hes-related family bHLH transcription factor with YRPW motif-like	pulmonary valve morphogenesis	Biological process	-
KIF3C	3797	kinesin family member 3C	ATP binding	Molecular function	-
TGM2	7052	transglutaminase 2	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway	Biological process	-
UGT2B10	7365	UDP glucuronosyltransferase 2 family, polypeptide B10	integral component of membrane	Cellular component	-
RPS19	6223	ribosomal protein S19	focal adhesion	Cellular component	21423176
CSGALNACT2	55454	chondroitin sulfate N-acetylgalactosaminyltransferase 2	chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	Biological process	11788602
EXTL3	2137	exostosin-like glycosyltransferase 3	metal ion binding	Molecular function	-
WIBG	84305	within bgcn homolog (Drosophila)	nucleolus	Cellular component	-
PKP4	8502	plakophilin 4	desmosome	Cellular component	8937994
PIK3R5	23533	phosphoinositide-3-kinase, regulatory subunit 5	phosphatidylinositol biosynthetic process	Biological process	-
SOD1	6647	superoxide dismutase 1, soluble	cellular response to potassium ion	Biological process	-
CYP2J2	1573	cytochrome P450, family 2, subfamily J, polypeptide 2	exogenous drug catabolic process	Biological process	-
HOMER2	9455	homer scaffolding protein 2	neuronal postsynaptic density	Cellular component	-
USP9Y	8287	ubiquitin specific peptidase 9, Y-linked	cysteine-type peptidase activity	Molecular function	8922996
GRIN2A	2903	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	dopamine metabolic process	Biological process	-
AKT1	207	v-akt murine thymoma viral oncogene homolog 1	protein phosphorylation	Biological process	11994271
GLUD2	2747	glutamate dehydrogenase 2	glutamate catabolic process	Biological process	11032875
TTC28	23331	tetratricopeptide repeat domain 28	regulation of mitotic cell cycle	Biological process	-
ERI3	79033	ERI1 exoribonuclease family member 3	metal ion binding	Molecular function	-
NR2F2	7026	nuclear receptor subfamily 2, group F, member 2	intracellular receptor signaling pathway	Biological process	1899293
CHP2	63928	calcineurin-like EF-hand protein 2	nucleus	Cellular component	21392185
TMEM8A	58986	transmembrane protein 8A	integral component of plasma membrane	Cellular component	11006113
TJAP1	93643	tight junction associated protein 1 (peripheral)	endosome	Cellular component	-
TBC1D21	161514	TBC1 domain family, member 21	Rab GTPase binding	Molecular function	16923123
S1PR3	1903	sphingosine-1-phosphate receptor 3	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway	Biological process	-
SLC1A2	6506	solute carrier family 1 (glial high affinity glutamate transporter), member 2	visual behavior	Biological process	-
APOC3	345	apolipoprotein C-III	regulation of Cdc42 protein signal transduction	Biological process	16443932
CYBB	1536	cytochrome b-245, beta polypeptide	voltage-gated ion channel activity	Molecular function	-
CCL2	6347	chemokine (C-C motif) ligand 2	maternal process involved in parturition	Biological process	-
SLC5A2	6524	solute carrier family 5 (sodium/glucose cotransporter), member 2	low-affinity glucose:sodium symporter activity	Molecular function	8244402
FUT7	2529	fucosyltransferase 7 (alpha (1,3) fucosyltransferase)	membrane	Cellular component	19946888
GHRHR	2692	growth hormone releasing hormone receptor	adenylate cyclase-activating G-protein coupled receptor signaling pathway	Biological process	1333056
CADM3	57863	cell adhesion molecule 3	cell-cell junction organization	Biological process	-
EEF1D	1936	eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)	signal transducer activity	Molecular function	12761501
KCNJ2	3759	potassium channel, inwardly rectifying subfamily J, member 2	intercalated disc	Cellular component	-
HIPK4	147746	homeodomain interacting protein kinase 4	histone phosphorylation	Biological process	-
TRIM11	81559	tripartite motif containing 11	negative regulation of viral transcription	Biological process	18248090
MRPS31	10240	mitochondrial ribosomal protein S31	structural constituent of ribosome	Molecular function	-
SMAD3	4088	SMAD family member 3	positive regulation of interleukin-1 beta production	Biological process	-
BUB3	9184	BUB3 mitotic checkpoint protein	cell division	Biological process	-
ERP29	10961	endoplasmic reticulum protein 29	protein disulfide isomerase activity	Molecular function	9738895
CITED1	4435	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1	cytoplasm	Cellular component	16864582
RELN	5649	reelin	dendrite development	Biological process	-
ZEB1	6935	zinc finger E-box binding homeobox 1	transcription, DNA-templated	Biological process	-
CALM3	808	calmodulin 3 (phosphorylase kinase, delta)	fibroblast growth factor receptor signaling pathway	Biological process	-
SPHAR	10638	S-phase response (cyclin related)	DNA replication	Biological process	7799938
MYADM	91663	myeloid-associated differentiation marker	cell-cell junction maintenance	Biological process	23264465
PLIN4	729359	perilipin 4	plasma membrane	Cellular component	-
RIPK2	8767	receptor-interacting serine-threonine kinase 2	signal transducer activity	Molecular function	9642260
SORT1	6272	sortilin 1	nerve growth factor binding	Molecular function	14985763
FLOT2	2319	flotillin 2	cell adhesion	Biological process	-
SLC19A3	80704	solute carrier family 19 (thiamine transporter), member 3	plasma membrane	Cellular component	-
ARMC5	79798	armadillo repeat containing 5	cytoplasm	Cellular component	24283224
ACADS	35	acyl-CoA dehydrogenase, C-2 to C-3 short chain	response to glucocorticoid	Biological process	-
TMED1	11018	transmembrane emp24 protein transport domain containing 1	endoplasmic reticulum membrane	Cellular component	-
KRTAP9-9	81870	keratin associated protein 9-9	keratin filament	Cellular component	-
BBS1	582	Bardet-Biedl syndrome 1	patched binding	Molecular function	22228099
TAOK3	51347	TAO kinase 3	cytoplasm	Cellular component	-
MS4A12	54860	membrane-spanning 4-domains, subfamily A, member 12	integral component of membrane	Cellular component	-
MYO5A	4644	myosin VA (heavy chain 12, myoxin)	locomotion involved in locomotory behavior	Biological process	-
IKBKB	3551	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	CD40 receptor complex	Cellular component	-
HS3ST5	222537	heparan sulfate (glucosamine) 3-O-sulfotransferase 5	small molecule metabolic process	Biological process	-
DPT	1805	dermatopontin	collagen fibril organization	Biological process	-
DICER1	23405	dicer 1, ribonuclease type III	regulation of cell cycle	Biological process	-
PAXBP1	94104	PAX3 and PAX7 binding protein 1	regulation of satellite cell proliferation	Biological process	-
NLK	51701	nemo-like kinase	protein phosphorylation	Biological process	-
OR6K6	128371	olfactory receptor, family 6, subfamily K, member 6	transmembrane signaling receptor activity	Molecular function	-
ITIH4	3700	inter-alpha-trypsin inhibitor heavy chain family, member 4	plasma membrane	Cellular component	-
HIC2	23119	hypermethylated in cancer 2	nucleus	Cellular component	11554746
RPH3A	22895	rabphilin 3A	calcium-dependent phospholipid binding	Molecular function	-
PRKG2	5593	protein kinase, cGMP-dependent, type II	cytosol	Cellular component	-
ATXN7	6314	ataxin 7	nucleoplasm	Cellular component	-
PHF1	5252	PHD finger protein 1	positive regulation of histone H3-K27 methylation	Biological process	23273982
NPPC	4880	natriuretic peptide C	negative regulation of meiotic cell cycle	Biological process	20947764
SYNGAP1	8831	synaptic Ras GTPase activating protein 1	regulation of MAPK cascade	Biological process	-
TUBG1	7283	tubulin, gamma 1	GTPase activity	Molecular function	-
CERS6	253782	ceramide synthase 6	endoplasmic reticulum membrane	Cellular component	-
ERBB2	2064	erb-b2 receptor tyrosine kinase 2	protein heterodimerization activity	Molecular function	7556068
BCL11A	53335	B-cell CLL/lymphoma 11A (zinc finger protein)	negative regulation of collateral sprouting	Biological process	19616629
PIN1	5300	peptidylprolyl cis/trans isomerase, NIMA-interacting 1	phosphoserine binding	Molecular function	10037602
PDS5B	23047	PDS5 cohesin associated factor B	chromosome, centromeric region	Cellular component	-
OR2M4	26245	olfactory receptor, family 2, subfamily M, member 4	plasma membrane	Cellular component	-
MARS	4141	methionyl-tRNA synthetase	tRNA aminoacylation for protein translation	Biological process	-
OR5D13	390142	olfactory receptor, family 5, subfamily D, member 13 (gene/pseudogene)	plasma membrane	Cellular component	-
PLK1	5347	polo-like kinase 1	spindle midzone	Cellular component	19468302
ZBTB40	9923	zinc finger and BTB domain containing 40	cellular response to DNA damage stimulus	Biological process	17525332
ZNF664	144348	zinc finger protein 664	regulation of transcription, DNA-templated	Biological process	-
ZNF683	257101	zinc finger protein 683	RNA polymerase II regulatory region sequence-specific DNA binding	Molecular function	-
GRIA2	2891	glutamate receptor, ionotropic, AMPA 2	ion transmembrane transport	Biological process	-
ROR1	4919	receptor tyrosine kinase-like orphan receptor 1	ATP binding	Molecular function	-
USP9Y	8287	ubiquitin specific peptidase 9, Y-linked	spermatogenesis	Biological process	9384609
PCYOX1L	78991	prenylcysteine oxidase 1 like	membrane	Cellular component	19946888
SUV39H1	6839	suppressor of variegation 3-9 homolog 1 (Drosophila)	viral process	Biological process	-
USP50	373509	ubiquitin specific peptidase 50	cysteine-type endopeptidase activity	Molecular function	-
PIK3R4	30849	phosphoinositide-3-kinase, regulatory subunit 4	positive regulation of phosphatidylinositol 3-kinase activity	Biological process	21062745
GGTLC1	92086	gamma-glutamyltransferase light chain 1	anchored component of external side of plasma membrane	Cellular component	18357469
CENPF	1063	centromere protein F, 350/400kDa	chromatin binding	Molecular function	9891037
MAGEA3	4102	melanoma antigen family A3	protein binding	Molecular function	20864041
ITPR3	3710	inositol 1,4,5-trisphosphate receptor, type 3	intracellular ligand-gated calcium channel activity	Molecular function	-
FHIT	2272	fragile histidine triad	ubiquitin protein ligase binding	Molecular function	15313915
SULT1C2	6819	sulfotransferase family, cytosolic, 1C, member 2	extracellular exosome	Cellular component	23376485
ALDH3B2	222	aldehyde dehydrogenase 3 family, member B2	lipid metabolic process	Biological process	8890755
TET3	200424	tet methylcytosine dioxygenase 3	positive regulation of transcription from RNA polymerase II promoter	Biological process	23353889
RNF19B	127544	ring finger protein 19B	ligase activity	Molecular function	-
MEFV	4210	Mediterranean fever	microtubule associated complex	Cellular component	11468188
PARP4	143	poly (ADP-ribose) polymerase family, member 4	extracellular exosome	Cellular component	19056867
FARSB	10056	phenylalanyl-tRNA synthetase, beta subunit	cytoplasm	Cellular component	10049785
PLCD1	5333	phospholipase C, delta 1	cytoplasm	Cellular component	15702972
PLCL1	5334	phospholipase C-like 1	signal transducer activity	Molecular function	-
ADAMTS12	81792	ADAM metallopeptidase with thrombospondin type 1 motif, 12	cellular response to BMP stimulus	Biological process	22247065
CD84	8832	CD84 molecule	integral component of plasma membrane	Cellular component	9310491
ZNF274	10782	zinc finger protein 274	sequence-specific DNA binding	Molecular function	21170338
SUPT4H1	6827	suppressor of Ty 4 homolog 1 (S. cerevisiae)	protein binding	Molecular function	10075709
COL12A1	1303	collagen, type XII, alpha 1	extracellular space	Cellular component	20551380
PLXNA3	55558	plexin A3	branchiomotor neuron axon guidance	Biological process	-
MARCO	8685	macrophage receptor with collagenous structure	collagen trimer	Cellular component	-
RAB12	201475	RAB12, member RAS oncogene family	vesicle docking involved in exocytosis	Biological process	-
CYP4F11	57834	cytochrome P450, family 4, subfamily F, polypeptide 11	endoplasmic reticulum membrane	Cellular component	-
DRD1	1812	dopamine receptor D1	nucleus	Cellular component	-
MAP1LC3B	81631	microtubule-associated protein 1 light chain 3 beta	microtubule binding	Molecular function	-
ATOH1	474	atonal homolog 1 (Drosophila)	inner ear morphogenesis	Biological process	-
COL4A3BP	10087	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein	protein binding	Molecular function	10212244
ATP6V0B	533	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b	insulin receptor signaling pathway	Biological process	-
ASPN	54829	asporin	collagen binding	Molecular function	-
HEYL	26508	hes-related family bHLH transcription factor with YRPW motif-like	glomerulus development	Biological process	-
UGT1A5	54579	UDP glucuronosyltransferase 1 family, polypeptide A5	integral component of membrane	Cellular component	-
NELFA	7469	negative elongation factor complex member A	cytoplasm	Cellular component	-
STAB2	55576	stabilin 2	protein binding	Molecular function	18519035
ACTR3	10096	ARP3 actin-related protein 3 homolog (yeast)	Arp2/3 complex-mediated actin nucleation	Biological process	11741539
RAB8A	4218	RAB8A, member RAS oncogene family	Golgi vesicle fusion to target membrane	Biological process	17574030
FKBP8	23770	FK506 binding protein 8, 38kDa	chaperone-mediated protein folding	Biological process	-
EEF2	1938	eukaryotic translation elongation factor 2	poly(A) RNA binding	Molecular function	22658674
CNGA2	1260	cyclic nucleotide gated channel alpha 2	cGMP binding	Molecular function	-
SPANXC	64663	SPANX family, member C	molecular_function	Molecular function	-
KL	9365	klotho	neurotrophin TRK receptor signaling pathway	Biological process	-
DNMT3A	1788	DNA (cytosine-5-)-methyltransferase 3 alpha	S-adenosylmethioninamine metabolic process	Biological process	-
RABGAP1L	9910	RAB GTPase activating protein 1-like	positive regulation of GTPase activity	Biological process	-
TAS2R41	259287	taste receptor, type 2, member 41	plasma membrane	Cellular component	-
SPIDR	23514	scaffolding protein involved in DNA repair	positive regulation of double-strand break repair	Biological process	23509288
RPL14	9045	ribosomal protein L14	rRNA processing	Biological process	18697920
CRP	1401	C-reactive protein, pentraxin-related	aging	Biological process	-
WNT9B	7484	wingless-type MMTV integration site family, member 9B	collecting duct development	Biological process	-
CHMP4C	92421	charged multivesicular body protein 4C	protein transport	Biological process	-
GUCA2A	2980	guanylate cyclase activator 2A (guanylin)	extracellular region	Cellular component	8095028
PTGES	9536	prostaglandin E synthase	acute inflammatory response	Biological process	-
MYO1F	4542	myosin IF	positive regulation of cell migration	Biological process	-
CNOT11	55571	CCR4-NOT transcription complex, subunit 11	molecular_function	Molecular function	-
ADSSL1	122622	adenylosuccinate synthase like 1	purine nucleobase metabolic process	Biological process	-
MTRR	4552	5-methyltetrahydrofolate-homocysteine methyltransferase reductase	homocysteine catabolic process	Biological process	11466310
IL10	3586	interleukin 10	negative regulation of nitric oxide biosynthetic process	Biological process	-
CYP2J2	1573	cytochrome P450, family 2, subfamily J, polypeptide 2	arachidonic acid epoxygenase activity	Molecular function	11901223
AP1AR	55435	adaptor-related protein complex 1 associated regulatory protein	protein transport	Biological process	-
GNAT1	2779	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1	signal transduction	Biological process	17584859
NDUFA3	4696	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa	integral component of membrane	Cellular component	-
UNC13B	10497	unc-13 homolog B (C. elegans)	synaptic vesicle priming	Biological process	-
CHCHD1	118487	coiled-coil-helix-coiled-coil-helix domain containing 1	mitochondrion	Cellular component	-
NFKB2	4791	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	toll-like receptor signaling pathway	Biological process	-
ZMAT3	64393	zinc finger, matrin-type 3	apoptotic process	Biological process	-
MBL2	4153	mannose-binding lectin (protein C) 2, soluble	mannose binding	Molecular function	2477488
SNRPF	6636	small nuclear ribonucleoprotein polypeptide F	transcription from RNA polymerase II promoter	Biological process	-
AKAP13	11214	A kinase (PRKA) anchor protein 13	small GTPase mediated signal transduction	Biological process	-
ULBP2	80328	UL16 binding protein 2	antigen processing and presentation of peptide antigen via MHC class I	Biological process	-
CDKN3	1033	cyclin-dependent kinase inhibitor 3	G1/S transition of mitotic cell cycle	Biological process	8127873
CD24	100133941	CD24 molecule	signal transducer activity	Molecular function	8213086
FRMD4A	55691	FERM domain containing 4A	cytoplasm	Cellular component	-
IAPP	3375	islet amyloid polypeptide	hormone activity	Molecular function	-
ACKR3	57007	atypical chemokine receptor 3	G-protein coupled receptor signaling pathway	Biological process	-
ARF1	375	ADP-ribosylation factor 1	viral process	Biological process	-
AHR	196	aryl hydrocarbon receptor	protein binding	Molecular function	10395741
ANXA2	302	annexin A2	calcium-dependent phospholipid binding	Molecular function	2138016
CRHBP	1393	corticotropin releasing hormone binding protein	dense core granule	Cellular component	-
UBE2U	148581	ubiquitin-conjugating enzyme E2U (putative)	cytoplasm	Cellular component	-
MMADHC	27249	methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria	small molecule metabolic process	Biological process	-
MSC	9242	musculin	nucleus	Cellular component	-
TNK2	10188	tyrosine kinase, non-receptor, 2	negative regulation of GTPase activity	Biological process	8497321
DUSP3	1845	dual specificity phosphatase 3	negative regulation of JNK cascade	Biological process	19010898
COL3A1	1281	collagen, type III, alpha 1	positive regulation of Rho protein signal transduction	Biological process	-
ETS2	2114	v-ets avian erythroblastosis virus E26 oncogene homolog 2	positive regulation of transcription, DNA-templated	Biological process	11909962
ZKSCAN3	80317	zinc finger with KRAB and SCAN domains 3	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	18940803
ANGPT4	51378	angiopoietin 4	positive regulation of endothelial cell migration	Biological process	12958144
GRIN1	2902	glutamate receptor, ionotropic, N-methyl D-aspartate 1	glutamate receptor binding	Molecular function	-
RBX1	9978	ring-box 1, E3 ubiquitin protein ligase	ubiquitin protein ligase binding	Molecular function	17636018
RAE1	8480	ribonucleic acid export 1	nuclear envelope	Cellular component	-
EGFR	1956	epidermal growth factor receptor	positive regulation of inflammatory response	Biological process	-
KRT18	3875	keratin 18, type I	intermediate filament	Cellular component	10852826
SHANK3	85358	SH3 and multiple ankyrin repeat domains 3	actin binding	Molecular function	-
PKLR	5313	pyruvate kinase, liver and RBC	response to hypoxia	Biological process	-
PLSCR3	57048	phospholipid scramblase 3	phospholipid scramblase activity	Molecular function	10930526
SCN9A	6335	sodium channel, voltage gated, type IX alpha subunit	voltage-gated sodium channel complex	Cellular component	-
HAX1	10456	HCLS1 associated protein X-1	regulation of protein targeting to mitochondrion	Biological process	24522549
UBXN2A	165324	UBX domain protein 2A	regulation of catalytic activity	Biological process	-
KIF13A	63971	kinesin family member 13A	ATPase activity	Molecular function	-
RILPL2	196383	Rab interacting lysosomal protein-like 2	centrosome	Cellular component	-
KDM4D	55693	lysine (K)-specific demethylase 4D	regulation of transcription, DNA-templated	Biological process	-
NUPR1	26471	nuclear protein, transcriptional regulator, 1	response to toxic substance	Biological process	-
ZC2HC1A	51101	zinc finger, C2HC-type containing 1A	protein binding	Molecular function	25416956
ITM2B	9445	integral membrane protein 2B	extrinsic apoptotic signaling pathway in absence of ligand	Biological process	-
AIMP1	9255	aminoacyl tRNA synthetase complex-interacting multifunctional protein 1	cytosol	Cellular component	-
HAO2	51179	hydroxyacid oxidase 2 (long chain)	peroxisome	Cellular component	10777549
OR6C3	254786	olfactory receptor, family 6, subfamily C, member 3	plasma membrane	Cellular component	-
ITSN2	50618	intersectin 2	positive regulation of signal transduction	Biological process	9630982
MSH2	4436	mutS homolog 2	postreplication repair	Biological process	7923193
MAML1	9794	mastermind-like 1 (Drosophila)	atrioventricular node development	Biological process	-
HSPA1A	3303	heat shock 70kDa protein 1A	cytoplasm	Cellular component	16130169
POMT2	29954	protein-O-mannosyltransferase 2	protein O-linked mannosylation	Biological process	-
HIST1H4D	8360	histone cluster 1, H4d	histone binding	Molecular function	20498094
GNAS	2778	GNAS complex locus	regulation of signal transduction	Biological process	12719376
SMC1A	8243	structural maintenance of chromosomes 1A	poly(A) RNA binding	Molecular function	22681889
SMAGP	57228	small cell adhesion glycoprotein	plasma membrane	Cellular component	-
LDLR	3949	low density lipoprotein receptor	late endosome	Cellular component	17461796
TP63	8626	tumor protein p63	positive regulation of transcription, DNA-templated	Biological process	9774969
PDPK1	5170	3-phosphoinositide dependent protein kinase 1	positive regulation of phospholipase activity	Biological process	22454520
DNAJA1	3301	DnaJ (Hsp40) homolog, subfamily A, member 1	response to unfolded protein	Biological process	8334160
EDNRA	1909	endothelin receptor type A	positive regulation of kidney development	Biological process	-
DVL1	1855	dishevelled segment polarity protein 1	neurotransmitter secretion	Biological process	-
NONO	4841	non-POU domain containing, octamer-binding	negative regulation of transcription, DNA-templated	Biological process	-
PCSK5	5125	proprotein convertase subtilisin/kexin type 5	embryo implantation	Biological process	8940009
SCYL2	55681	SCY1-like 2 (S. cerevisiae)	ATP binding	Molecular function	-
AKAP4	8852	A kinase (PRKA) anchor protein 4	cytoskeleton	Cellular component	9822690
PROS1	5627	protein S (alpha)	platelet degranulation	Biological process	-
GNB3	2784	guanine nucleotide binding protein (G protein), beta polypeptide 3	signal transducer activity	Molecular function	-
MN1	4330	meningioma (disrupted in balanced translocation) 1	molecular_function	Molecular function	-
FXYD4	53828	FXYD domain containing ion transport regulator 4	sodium channel regulator activity	Molecular function	-
CSTF1	1477	cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa	mRNA cleavage	Biological process	1358884
ALKBH4	54784	alkB, alkylation repair homolog 4 (E. coli)	actomyosin structure organization	Biological process	23673617
TRIM31	11074	tripartite motif containing 31	negative regulation of viral transcription	Biological process	18248090
SYNE1	23345	spectrin repeat containing, nuclear envelope 1	muscle cell differentiation	Biological process	11792814
HPSE2	60495	heparanase 2 (inactive)	small molecule metabolic process	Biological process	-
PNMT	5409	phenylethanolamine N-methyltransferase	phenylethanolamine N-methyltransferase activity	Molecular function	-
PIM3	415116	Pim-3 proto-oncogene, serine/threonine kinase	protein autophosphorylation	Biological process	-
DYNLL1	8655	dynein, light chain, LC8-type 1	antigen processing and presentation of exogenous peptide antigen via MHC class II	Biological process	-
NFE2L2	4780	nuclear factor, erythroid 2-like 2	transcription cofactor binding	Molecular function	-
HCRTR1	3061	hypocretin (orexin) receptor 1	orexin receptor activity	Molecular function	-
PER2	8864	period circadian clock 2	negative regulation of transcription regulatory region DNA binding	Biological process	-
GATA3	2625	GATA binding protein 3	E-box binding	Molecular function	20855495
CD84	8832	CD84 molecule	defense response	Biological process	9310491
SPA17	53340	sperm autoantigenic protein 17	cytoplasm	Cellular component	18421703
OSR2	116039	odd-skipped related transciption factor 2	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
MESP1	55897	mesoderm posterior basic helix-loop-helix transcription factor 1	lateral mesoderm development	Biological process	-
CTNNBL1	56259	catenin, beta like 1	mRNA splicing, via spliceosome	Biological process	-
PGLYRP2	114770	peptidoglycan recognition protein 2	growth of symbiont in host	Biological process	-
UCK1	83549	uridine-cytidine kinase 1	phosphorylation	Biological process	-
LRP1	4035	low density lipoprotein receptor-related protein 1	regulation of actin cytoskeleton organization	Biological process	-
FXYD6P3	406875	FXYD domain containing ion transport regulator 6 pseudogene 3	integral component of membrane	Cellular component	-
DPCD	25911	deleted in primary ciliary dyskinesia homolog (mouse)	determination of left/right symmetry	Biological process	-
LPIN2	9663	lipin 2	transcription coactivator activity	Molecular function	-
NPEPPS	9520	aminopeptidase puromycin sensitive	nucleus	Cellular component	-
SRC	6714	SRC proto-oncogene, non-receptor tyrosine kinase	nucleus	Cellular component	-
HDAC10	83933	histone deacetylase 10	histone deacetylase binding	Molecular function	11861901
CHCHD10	400916	coiled-coil-helix-coiled-coil-helix domain containing 10	ATP biosynthetic process	Biological process	20888800
NAE1	8883	NEDD8 activating enzyme E1 subunit 1	mitotic DNA replication checkpoint	Biological process	10722740
NREP	9315	neuronal regeneration related protein	regulation of neuron differentiation	Biological process	-
GJD3	125111	gap junction protein, delta 3, 31.9kDa	ion transmembrane transport	Biological process	-
CSNK1D	1453	casein kinase 1, delta	protein serine/threonine kinase activity	Molecular function	-
DAG1	1605	dystroglycan 1 (dystrophin-associated glycoprotein 1)	sarcolemma	Cellular component	-
DRD4	1815	dopamine receptor D4	response to histamine	Biological process	16839358
CDK6	1021	cyclin-dependent kinase 6	ruffle	Cellular component	10205165
DAPP1	27071	dual adaptor of phosphotyrosine and 3-phosphoinositides	cytosol	Cellular component	-
HERC5	51191	HECT and RLD domain containing E3 ubiquitin protein ligase 5	cytosol	Cellular component	-
CYP4F2	8529	cytochrome P450, family 4, subfamily F, polypeptide 2	long-chain fatty acid metabolic process	Biological process	18433732
BCL2L1	598	BCL2-like 1	cellular response to gamma radiation	Biological process	-
STX7	8417	syntaxin 7	tertiary granule	Cellular component	20170677
TMED9	54732	transmembrane emp24 protein transport domain containing 9	trans-Golgi network transport vesicle	Cellular component	9527489
AKT2	208	v-akt murine thymoma viral oncogene homolog 2	protein localization to plasma membrane	Biological process	-
GJA1	2697	gap junction protein, alpha 1, 43kDa	negative regulation of cardiac muscle cell proliferation	Biological process	-
CPEB3	22849	cytoplasmic polyadenylation element binding protein 3	translation repressor activity, nucleic acid binding	Molecular function	-
CORO1B	57175	coronin, actin binding protein, 1B	ruffle organization	Biological process	16027158
SIRT5	23408	sirtuin 5	chromatin silencing	Biological process	10381378
LENG9	94059	leukocyte receptor cluster (LRC) member 9	metal ion binding	Molecular function	-
OGN	4969	osteoglycin	extracellular region	Cellular component	-
CAPRIN2	65981	caprin family member 2	positive regulation of canonical Wnt signaling pathway	Biological process	18762581
CHRNA3	1136	cholinergic receptor, nicotinic, alpha 3 (neuronal)	synaptic transmission	Biological process	-
ARMT1	79624	acidic residue methyltransferase 1	protein methylation	Biological process	25732820
WNT11	7481	wingless-type MMTV integration site family, member 11	negative regulation of cell death	Biological process	20219091
CHRNA5	1138	cholinergic receptor, nicotinic, alpha 5 (neuronal)	acetylcholine receptor activity	Molecular function	1542648
TNFRSF14	8764	tumor necrosis factor receptor superfamily, member 14	protein binding	Molecular function	10318773
CXCR1	3577	chemokine (C-X-C motif) receptor 1	cell surface receptor signaling pathway	Biological process	10734056
ROCK2	9475	Rho-associated, coiled-coil containing protein kinase 2	poly(A) RNA binding	Molecular function	22681889
RNF6	6049	ring finger protein (C3H2C3 type) 6	protein K27-linked ubiquitination	Biological process	19345326
SLC2A1	6513	solute carrier family 2 (facilitated glucose transporter), member 1	identical protein binding	Molecular function	1429721
ALOX5AP	241	arachidonate 5-lipoxygenase-activating protein	arachidonic acid metabolic process	Biological process	-
GLI1	2735	GLI family zinc finger 1	digestive tract morphogenesis	Biological process	11001584
NID2	22795	nidogen 2 (osteonidogen)	collagen binding	Molecular function	9733643
DTX1	1840	deltex 1, E3 ubiquitin ligase	SH3 domain binding	Molecular function	-
B3GNT9	84752	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9	integral component of membrane	Cellular component	-
SEC61G	23480	Sec61 gamma subunit	protein binding	Molecular function	25416956
OR3A3	8392	olfactory receptor, family 3, subfamily A, member 3	plasma membrane	Cellular component	-
PPP2R5C	5527	protein phosphatase 2, regulatory subunit B', gamma	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological process	16717086
DTNBP1	84062	dystrobrevin binding protein 1	dendritic spine	Cellular component	-
HLA-DRB1	3123	major histocompatibility complex, class II, DR beta 1	peptide antigen binding	Molecular function	-
IL23A	51561	interleukin 23, alpha subunit p19	positive regulation of defense response to virus by host	Biological process	-
TRAF1	7185	TNF receptor-associated factor 1	thioesterase binding	Molecular function	11279055
DVL2	1856	dishevelled segment polarity protein 2	apical part of cell	Cellular component	-
ZFPL1	7542	zinc finger protein-like 1	DNA binding	Molecular function	9653652
COL22A1	169044	collagen, type XXII, alpha 1	endoplasmic reticulum lumen	Cellular component	-
TMEM203	94107	transmembrane protein 203	integral component of membrane	Cellular component	-
ADCY8	114	adenylate cyclase 8 (brain)	epidermal growth factor receptor signaling pathway	Biological process	-
MMP8	4317	matrix metallopeptidase 8	metalloendopeptidase activity	Molecular function	-
LCN9	392399	lipocalin 9	extracellular region	Cellular component	-
SNX12	29934	sorting nexin 12	negative regulation of protein processing	Biological process	22709416
KCNC3	3748	potassium channel, voltage gated Shaw related subfamily C, member 3	synaptic transmission	Biological process	-
BAX	581	BCL2-associated X protein	viral process	Biological process	-
GRID2IP	392862	glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein	cell junction	Cellular component	-
HILPDA	29923	hypoxia inducible lipid droplet-associated	secretory granule	Cellular component	15930302
RIC8A	60626	RIC8 guanine nucleotide exchange factor A	G-protein alpha-subunit binding	Molecular function	-
WFS1	7466	Wolfram syndrome 1 (wolframin)	positive regulation of growth	Biological process	-
CDC42	998	cell division cycle 42	negative regulation of epidermal growth factor receptor signaling pathway	Biological process	-
ATP10A	57194	ATPase, class V, type 10A	plasma membrane	Cellular component	-
SGIP1	84251	SH3-domain GRB2-like (endophilin) interacting protein 1	AP-2 adaptor complex	Cellular component	-
PSMA6	5687	proteasome (prosome, macropain) subunit, alpha type, 6	nucleoplasm	Cellular component	-
CYP2R1	120227	cytochrome P450, family 2, subfamily R, polypeptide 1	oxidation-reduction process	Biological process	-
IRX3	79191	iroquois homeobox 3	axon	Cellular component	-
APP	351	amyloid beta (A4) precursor protein	response to oxidative stress	Biological process	-
MYH10	4628	myosin, heavy chain 10, non-muscle	myosin II filament	Cellular component	24072716
IL1RN	3557	interleukin 1 receptor antagonist	response to interleukin-1	Biological process	-
FUT2	2524	fucosyltransferase 2 (secretor status included)	integral component of membrane	Cellular component	-
DICER1	23405	dicer 1, ribonuclease type III	lung development	Biological process	-
LPL	4023	lipoprotein lipase	positive regulation of macrophage derived foam cell differentiation	Biological process	12573449
SULT4A1	25830	sulfotransferase family 4A, member 1	steroid metabolic process	Biological process	-
TRIM7	81786	tripartite motif containing 7	nucleus	Cellular component	11331580
UCN	7349	urocortin	G-protein coupled receptor signaling pathway	Biological process	8612563
FGF12	2257	fibroblast growth factor 12	cell-cell signaling	Biological process	10049777
EPHA4	2043	EPH receptor A4	cytoplasm	Cellular component	-
RPL28	6158	ribosomal protein L28	translational termination	Biological process	-
SNRNP70	6625	small nuclear ribonucleoprotein 70kDa (U1)	protein binding	Molecular function	14561889
RAB38	23682	RAB38, member RAS oncogene family	plasma membrane	Cellular component	-
SLC25A42	284439	solute carrier family 25, member 42	AMP transport	Biological process	19429682
SCRIB	23513	scribbled planar cell polarity protein	lamellipodium	Cellular component	-
PTPN2	5771	protein tyrosine phosphatase, non-receptor type 2	negative regulation of interleukin-2-mediated signaling pathway	Biological process	11909529
ARHGAP6	395	Rho GTPase activating protein 6	cytoplasm	Cellular component	10699171
PMS2	5395	PMS2 postmeiotic segregation increased 2 (S. cerevisiae)	nucleic acid phosphodiester bond hydrolysis	Biological process	-
P2RX7	5027	purinergic receptor P2X, ligand gated ion channel, 7	protein homodimerization activity	Molecular function	17895406
TIGIT	201633	T cell immunoreceptor with Ig and ITIM domains	plasma membrane	Cellular component	-
RORA	6095	RAR-related orphan receptor A	core promoter sequence-specific DNA binding	Molecular function	21628546
BRAF	673	B-Raf proto-oncogene, serine/threonine kinase	long-term synaptic potentiation	Biological process	-
MUC3A	4584	mucin 3A, cell surface associated	integral component of membrane	Cellular component	10405327
FLOT1	10211	flotillin 1	integral component of membrane	Cellular component	9153235
HIST1H4F	8361	histone cluster 1, H4f	histone binding	Molecular function	20498094
CDKN2A	1029	cyclin-dependent kinase inhibitor 2A	negative regulation of ubiquitin-protein transferase activity	Biological process	-
SSTR4	6754	somatostatin receptor 4	synaptic transmission	Biological process	-
NHLRC1	378884	NHL repeat containing E3 ubiquitin protein ligase 1	small molecule metabolic process	Biological process	-
PLXNB3	5365	plexin B3	Rho GDP-dissociation inhibitor binding	Molecular function	-
WNT16	51384	wingless-type MMTV integration site family, member 16	positive regulation of phosphatidylinositol 3-kinase signaling	Biological process	19951988
DDR1	780	discoidin domain receptor tyrosine kinase 1	protein tyrosine kinase collagen receptor activity	Molecular function	21044884
B4GAT1	11041	beta-1,4-glucuronyltransferase 1	poly-N-acetyllactosamine biosynthetic process	Biological process	25279697
ASTL	431705	astacin-like metallo-endopeptidase (M12 family)	prevention of polyspermy	Biological process	22472438
LY96	23643	lymphocyte antigen 96	detection of lipopolysaccharide	Biological process	19252480
CSF2RB	1439	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	signal transduction	Biological process	1702217
CYP2J2	1573	cytochrome P450, family 2, subfamily J, polypeptide 2	linoleic acid metabolic process	Biological process	11901223
HK3	3101	hexokinase 3 (white cell)	mannokinase activity	Molecular function	-
APC2	10297	adenomatosis polyposis coli 2	cytoplasmic microtubule	Cellular component	10644998
BBS12	166379	Bardet-Biedl syndrome 12	eating behavior	Biological process	-
TESPA1	9840	thymocyte expressed, positive selection associated 1	positive regulation of T cell receptor signaling pathway	Biological process	-
FBXW7	55294	F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase	cyclin binding	Molecular function	12628165
OR14J1	442191	olfactory receptor, family 14, subfamily J, member 1	plasma membrane	Cellular component	-
ANXA4	307	annexin A4	epithelial cell differentiation	Biological process	21492153
LAX1	54900	lymphocyte transmembrane adaptor 1	immunoglobulin secretion	Biological process	-
TAZ	6901	tafazzin	glycerophospholipid biosynthetic process	Biological process	-
EIF5A2	56648	eukaryotic translation initiation factor 5A2	spermatogenesis	Biological process	11161802
TP53	7157	tumor protein p53	protein complex	Cellular component	9529249
HPX	3263	hemopexin	receptor-mediated endocytosis	Biological process	-
LRRK2	120892	leucine-rich repeat kinase 2	negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation	Biological process	21850687
PSIP1	11168	PC4 and SFRS1 interacting protein 1	nuclear heterochromatin	Cellular component	12796494
EFNA2	1943	ephrin-A2	anchored component of membrane	Cellular component	-
POLR2B	5431	polymerase (RNA) II (DNA directed) polypeptide B, 140kDa	transcription elongation from RNA polymerase II promoter	Biological process	-
ZFP36L1	677	ZFP36 ring finger protein-like 1	neural tube development	Biological process	-
SHPK	23729	sedoheptulokinase	ATP binding	Molecular function	-
PRKCA	5578	protein kinase C, alpha	negative regulation of glial cell apoptotic process	Biological process	9927633
NLRC3	197358	NLR family, CARD domain containing 3	cytoplasm	Cellular component	15705585
NFIA	4774	nuclear factor I/A	transcription factor binding	Molecular function	15684392
EIF3K	27335	eukaryotic translation initiation factor 3, subunit K	regulation of translational initiation	Biological process	-
SPATS2L	26010	spermatogenesis associated, serine-rich 2-like	protein complex	Cellular component	-
DOCK2	1794	dedicator of cytokinesis 2	cytoskeleton	Cellular component	-
FAM129A	116496	family with sequence similarity 129, member A	plasma membrane	Cellular component	-
IQGAP1	8826	IQ motif containing GTPase activating protein 1	lateral plasma membrane	Cellular component	-
FXYD4	53828	FXYD domain containing ion transport regulator 4	plasma membrane	Cellular component	-
AVPR1A	552	arginine vasopressin receptor 1A	regulation of systemic arterial blood pressure by vasopressin	Biological process	-
SMYD1	150572	SET and MYND domain containing 1	transcription corepressor activity	Molecular function	-
AURKC	6795	aurora kinase C	spindle	Cellular component	19774610
PABPN1L	390748	poly(A) binding protein, nuclear 1-like (cytoplasmic)	nucleotide binding	Molecular function	-
TFAP2A	7020	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	positive regulation of bone mineralization	Biological process	19578371
SNX14	57231	sorting nexin 14	cytoplasm	Cellular component	-
HIPK2	28996	homeodomain interacting protein kinase 2	cellular response to hypoxia	Biological process	18974774
HLA-DMA	3108	major histocompatibility complex, class II, DM alpha	positive thymic T cell selection	Biological process	-
IL17RE	132014	interleukin 17 receptor E	integral component of plasma membrane	Cellular component	-
SHANK2	22941	SH3 and multiple ankyrin repeat domains 2	long-term synaptic potentiation	Biological process	22699620
DDX50	79009	DEAD (Asp-Glu-Ala-Asp) box polypeptide 50	RNA secondary structure unwinding	Biological process	-
KIF14	9928	kinesin family member 14	response to docetaxel trihydrate	Biological process	24784001
TERF2IP	54386	telomeric repeat binding factor 2, interacting protein	telomere maintenance via telomere lengthening	Biological process	-
ERCC6	2074	excision repair cross-complementation group 6	nucleus	Cellular component	12560492
AK8	158067	adenylate kinase 8	ventricular system development	Biological process	-
CLDN22	53842	claudin 22	cell junction assembly	Biological process	-
CDH2	1000	cadherin 2, type 1, N-cadherin (neuronal)	cell migration	Biological process	-
AK3	50808	adenylate kinase 3	phosphorylation	Biological process	-
RGS9BP	388531	regulator of G protein signaling 9 binding protein	integral component of membrane	Cellular component	-
SNX4	8723	sorting nexin 4	protein binding	Molecular function	11278302
BRD7	29117	bromodomain containing 7	cytoplasm	Cellular component	10526152
PPY	5539	pancreatic polypeptide	feeding behavior	Biological process	-
GLT8D2	83468	glycosyltransferase 8 domain containing 2	transferase activity, transferring glycosyl groups	Molecular function	-
RAB33A	9363	RAB33A, member RAS oncogene family	GTP binding	Molecular function	-
RAD21	5885	RAD21 homolog (S. pombe)	DNA recombination	Biological process	8812457
OR9G4	283189	olfactory receptor, family 9, subfamily G, member 4	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
MEOX2	4223	mesenchyme homeobox 2	nucleus	Cellular component	22206000
BECN1	8678	beclin 1, autophagy related	viral process	Biological process	-
SULT1C4	27233	sulfotransferase family, cytosolic, 1C, member 4	sulfation	Biological process	20056724
HPX	3263	hemopexin	blood microparticle	Cellular component	22516433
HEY1	23462	hes-related family bHLH transcription factor with YRPW motif 1	Notch signaling involved in heart development	Biological process	17259303
DAB2	1601	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)	transforming growth factor beta receptor homodimeric complex	Cellular component	11387212
MICAL1	64780	microtubule associated monooxygenase, calponin and LIM domain containing 1	intermediate filament	Cellular component	11827972
CERS1	10715	ceramide synthase 1	sphingosine N-acyltransferase activity	Molecular function	-
BPIFA1	51297	BPI fold containing family A, member 1	negative regulation of single-species biofilm formation in or on host organism	Biological process	23499554
ENO2	2026	enolase 2 (gamma, neuronal)	extracellular exosome	Cellular component	20458337
MAT2A	4144	methionine adenosyltransferase II, alpha	S-adenosylmethionine biosynthetic process	Biological process	-
EIF4B	1975	eukaryotic translation initiation factor 4B	regulation of translational initiation	Biological process	2390971
DNAH12	201625	dynein, axonemal, heavy chain 12	cilium	Cellular component	-
ZNF263	10127	zinc finger protein 263	cytoplasm	Cellular component	-
SHC4	399694	SHC (Src homology 2 domain containing) family, member 4	protein kinase binding	Molecular function	-
ASS1	445	argininosuccinate synthase 1	aging	Biological process	-
MBOAT7	79143	membrane bound O-acyltransferase domain containing 7	layer formation in cerebral cortex	Biological process	-
ASB8	140461	ankyrin repeat and SOCS box containing 8	intracellular signal transduction	Biological process	-
C17orf67	339210	chromosome 17 open reading frame 67	protein binding	Molecular function	25416956
RPS27A	6233	ribosomal protein S27a	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	Biological process	-
CDC23	8697	cell division cycle 23	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	Biological process	-
TP53INP1	94241	tumor protein p53 inducible nuclear protein 1	negative regulation of cell migration	Biological process	-
FOXP3	50943	forkhead box P3	negative regulation of cytokine secretion	Biological process	11483607
IL6	3569	interleukin 6	positive regulation of leukocyte chemotaxis	Biological process	16034137
CAV3	859	caveolin 3	muscle organ development	Biological process	10988290
EGF	1950	epidermal growth factor	positive regulation of cerebellar granule cell precursor proliferation	Biological process	-
PPP6R1	22870	protein phosphatase 6, regulatory subunit 1	cytoplasm	Cellular component	-
GPR89B	51463	G protein-coupled receptor 89B	voltage-gated ion channel activity	Molecular function	-
IRS1	3667	insulin receptor substrate 1	phosphatidylinositol 3-kinase binding	Molecular function	-
ANAPC11	51529	anaphase promoting complex subunit 11	anaphase-promoting complex	Cellular component	11739784
ZKSCAN3	80317	zinc finger with KRAB and SCAN domains 3	negative regulation of autophagy	Biological process	23434374
KCNH8	131096	potassium channel, voltage gated eag related subfamily H, member 8	integral component of plasma membrane	Cellular component	-
UCN	7349	urocortin	neuropeptide signaling pathway	Biological process	-
NRAS	4893	neuroblastoma RAS viral (v-ras) oncogene homolog	establishment of protein localization to Golgi	Biological process	21968647
PPAP2C	8612	phosphatidic acid phosphatase type 2C	sphingolipid biosynthetic process	Biological process	-
TPH2	121278	tryptophan hydroxylase 2	response to estrogen	Biological process	-
PPP3CB	5532	protein phosphatase 3, catalytic subunit, beta isozyme	locomotion involved in locomotory behavior	Biological process	-
ADCYAP1R1	117	adenylate cyclase activating polypeptide 1 (pituitary) receptor type I	cAMP-mediated signaling	Biological process	-
MME	4311	membrane metallo-endopeptidase	dendrite	Cellular component	-
ATP9A	10079	ATPase, class II, type 9A	phospholipid-translocating ATPase activity	Molecular function	-
PIGK	10026	phosphatidylinositol glycan anchor biosynthesis, class K	GPI anchor binding	Molecular function	10793132
GVINP1	387751	GTPase, very large interferon inducible pseudogene 1	cytosol	Cellular component	-
ADGRL1	22859	adhesion G protein-coupled receptor L1	carbohydrate binding	Molecular function	-
MELK	9833	maternal embryonic leucine zipper kinase	ATP binding	Molecular function	-
PIK3CG	5294	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	T cell activation	Biological process	17290298
NCOA2	10499	nuclear receptor coactivator 2	cellular lipid metabolic process	Biological process	-
IFNA2	3440	interferon, alpha 2	positive regulation of transcription, DNA-templated	Biological process	17275127
SMPD4	55627	sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)	sphingomyelin catabolic process	Biological process	16517606
NUPL1	9818	nucleoporin like 1	carbohydrate metabolic process	Biological process	-
MRPS35	60488	mitochondrial ribosomal protein S35	mitochondrial small ribosomal subunit	Cellular component	11279123
KDR	3791	kinase insert domain receptor	positive regulation of endothelial cell migration	Biological process	10022831
TNFRSF19	55504	tumor necrosis factor receptor superfamily, member 19	JNK cascade	Biological process	10809768
PEX1	5189	peroxisomal biogenesis factor 1	ATPase activity, coupled	Molecular function	16854980
SLC39A9	55334	solute carrier family 39, member 9	transmembrane transport	Biological process	-
ATF4	468	activating transcription factor 4	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress	Biological process	23392669
TAF3	83860	TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa	negative regulation of transcription from RNA polymerase II promoter	Biological process	18549481
WAS	7454	Wiskott-Aldrich syndrome	regulation of catalytic activity	Biological process	8625410
DNMT1	1786	DNA (cytosine-5-)-methyltransferase 1	DNA (cytosine-5-)-methyltransferase activity	Molecular function	21745816
PADI6	353238	peptidyl arginine deiminase, type VI	cytoskeleton organization	Biological process	-
IFT172	26160	intraflagellar transport 172	bone development	Biological process	-
TSC22D2	9819	TSC22 domain family, member 2	sequence-specific DNA binding transcription factor activity	Molecular function	-
AQP1	358	aquaporin 1 (Colton blood group)	bicarbonate transport	Biological process	-
HSPB1	3315	heat shock 27kDa protein 1	extracellular space	Cellular component	22664934
CHERP	10523	calcium homeostasis endoplasmic reticulum protein	perinuclear region of cytoplasm	Cellular component	12656674
MBD3	53615	methyl-CpG binding domain protein 3	protein complex	Cellular component	16217013
TADA2B	93624	transcriptional adaptor 2B	zinc ion binding	Molecular function	-
MRGPRX4	117196	MAS-related GPR, member X4	G-protein coupled receptor signaling pathway	Biological process	-
ADCY9	115	adenylate cyclase 9	synaptic transmission	Biological process	-
PSMD1	5707	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	innate immune response	Biological process	-
AKR7A2	8574	aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)	phenanthrene-9,10-epoxide hydrolase activity	Molecular function	20837989
MYLK2	85366	myosin light chain kinase 2	myosin light chain kinase activity	Molecular function	-
SLC38A3	10991	solute carrier family 38, member 3	L-glutamine transmembrane transporter activity	Molecular function	10823827
SOX15	6665	SRY (sex determining region Y)-box 15	protein binding	Molecular function	25416956
IL1B	3553	interleukin 1, beta	embryo implantation	Biological process	16720713
NODAL	4838	nodal growth differentiation factor	transforming growth factor beta receptor binding	Molecular function	-
OR11H6	122748	olfactory receptor, family 11, subfamily H, member 6	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
HADH	3033	hydroxyacyl-CoA dehydrogenase	cytoplasm	Cellular component	-
ESRRB	2103	estrogen-related receptor beta	zinc ion binding	Molecular function	-
WNT7A	7476	wingless-type MMTV integration site family, member 7A	extracellular region	Cellular component	-
SLC35D2	11046	solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2	biological_process	Biological process	-
CAP1	10487	CAP, adenylate cyclase-associated protein 1 (yeast)	activation of adenylate cyclase activity	Biological process	7962207
ITGB3	3690	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	alphav-beta3 integrin-vitronectin complex	Cellular component	19267251
IFT20	90410	intraflagellar transport 20	primary cilium	Cellular component	-
PRMT8	56341	protein arginine methyltransferase 8	histone H4-R3 methylation	Biological process	-
SPARC	6678	secreted protein, acidic, cysteine-rich (osteonectin)	inner ear development	Biological process	-
CD74	972	CD74 molecule, major histocompatibility complex, class II invariant chain	positive regulation of B cell proliferation	Biological process	12782713
ACTA1	58	actin, alpha 1, skeletal muscle	extracellular space	Cellular component	23580065
IQGAP1	8826	IQ motif containing GTPase activating protein 1	midbody	Cellular component	15166316
ARL11	115761	ADP-ribosylation factor-like 11	intracellular	Cellular component	-
KDM4B	23030	lysine (K)-specific demethylase 4B	regulation of transcription, DNA-templated	Biological process	-
FCGR3B	2215	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)	positive regulation of defense response to virus by host	Biological process	22020285
HAPLN1	1404	hyaluronan and proteoglycan link protein 1	activation of mitophagy in response to mitochondrial depolarization	Biological process	22020285
CENPP	401541	centromere protein P	small GTPase mediated signal transduction	Biological process	-
MSH5	4439	mutS homolog 5	protein binding	Molecular function	16397227
IRAK1	3654	interleukin-1 receptor-associated kinase 1	positive regulation of NF-kappaB transcription factor activity	Biological process	-
NKX3-2	579	NK3 homeobox 2	skeletal system development	Biological process	9344671
ATP6AP1	537	ATPase, H+ transporting, lysosomal accessory protein 1	integral component of membrane	Cellular component	-
RBFOX1	54715	RNA binding protein, fox-1 homolog (C. elegans) 1	nucleus	Cellular component	-
HFE	3077	hemochromatosis	transferrin receptor binding	Molecular function	22728873
TBX2	6909	T-box 2	palate development	Biological process	-
OR13C6P	392311	olfactory receptor, family 13, subfamily C, member 6 pseudogene	G-protein coupled receptor activity	Molecular function	-
AKNA	80709	AT-hook transcription factor	positive regulation of transcription from RNA polymerase II promoter	Biological process	11268217
SEC24B	10427	SEC24 family member B	regulation of establishment of planar polarity involved in neural tube closure	Biological process	-
PLA2G4C	8605	phospholipase A2, group IVC (cytosolic, calcium-independent)	nuclear envelope	Cellular component	-
MYH10	4628	myosin, heavy chain 10, non-muscle	cytoplasm	Cellular component	-
AXIN1	8312	axin 1	canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation	Biological process	-
ASIC2	40	acid sensing (proton gated) ion channel 2	ion transmembrane transport	Biological process	-
MALT1	10892	MALT1 paracaspase	perinuclear region of cytoplasm	Cellular component	-
KPNB1	3837	karyopherin (importin) beta 1	zinc ion binding	Molecular function	7615630
SYT6	148281	synaptotagmin VI	regulation of calcium ion-dependent exocytosis	Biological process	-
KAT6A	7994	K(lysine) acetyltransferase 6A	cellular senescence	Biological process	23431171
RPL35	11224	ribosomal protein L35	poly(A) RNA binding	Molecular function	22658674
MAP1A	4130	microtubule-associated protein 1A	cytosol	Cellular component	-
HDAC5	10014	histone deacetylase 5	regulation of skeletal muscle fiber development	Biological process	-
GALE	2582	UDP-galactose-4-epimerase	protein homodimerization activity	Molecular function	16302980
DISC1	27185	disrupted in schizophrenia 1	protein binding	Molecular function	12812986
BMX	660	BMX non-receptor tyrosine kinase	mesoderm development	Biological process	9520419
ETFDH	2110	electron-transferring-flavoprotein dehydrogenase	integral component of mitochondrial inner membrane	Cellular component	8306995
CLSTN2	64084	calsyntenin 2	calcium ion binding	Molecular function	-
FNBP1L	54874	formin binding protein 1-like	vesicle transport along actin filament	Biological process	20730103
UCHL1	7345	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)	neuronal cell body	Cellular component	-
RNF41	10193	ring finger protein 41, E3 ubiquitin protein ligase	acid-amino acid ligase activity	Molecular function	-
C1QTNF1	114897	C1q and tumor necrosis factor related protein 1	positive regulation of cytosolic calcium ion concentration	Biological process	18171693
CELF1	10658	CUGBP, Elav-like family member 1	translation repressor activity, nucleic acid binding	Molecular function	10893231
SPEG	10290	SPEG complex locus	in utero embryonic development	Biological process	-
SNCB	6620	synuclein, beta	cytoplasm	Cellular component	-
TAPBP	6892	TAP binding protein (tapasin)	MHC class I protein binding	Molecular function	12788224
RPL11	6135	ribosomal protein L11	gene expression	Biological process	-
PDP2	57546	pyruvate dehyrogenase phosphatase catalytic subunit 2	regulation of acetyl-CoA biosynthetic process from pyruvate	Biological process	-
DVL1	1855	dishevelled segment polarity protein 1	cytosol	Cellular component	-
HTR1B	3351	5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled	response to mineralocorticoid	Biological process	-
ADCY2	108	adenylate cyclase 2 (brain)	adenylate cyclase-activating G-protein coupled receptor signaling pathway	Biological process	-
HSP90AA1	3320	heat shock protein 90kDa alpha (cytosolic), class A member 1	unfolded protein binding	Molecular function	-
FOXI2	399823	forkhead box I2	nucleus	Cellular component	-
LRPAP1	4043	low density lipoprotein receptor-related protein associated protein 1	asialoglycoprotein receptor activity	Molecular function	2229028
ABAT	18	4-aminobutyrate aminotransferase	neurotransmitter catabolic process	Biological process	15528998
GNG11	2791	guanine nucleotide binding protein (G protein), gamma 11	small molecule metabolic process	Biological process	-
TECR	9524	trans-2,3-enoyl-CoA reductase	cellular lipid metabolic process	Biological process	-
EML1	2009	echinoderm microtubule associated protein like 1	tubulin binding	Molecular function	24706829
RPN1	6184	ribophorin I	cellular protein modification process	Biological process	10660554
AK6	102157402	adenylate kinase 6	nucleoplasm	Cellular component	16079131
CELF3	11189	CUGBP, Elav-like family member 3	nucleus	Cellular component	11158314
USHBP1	83878	Usher syndrome 1C binding protein 1	protein binding	Molecular function	16189514
AKAP9	10142	A kinase (PRKA) anchor protein 9	synaptic transmission	Biological process	-
ESPN	83715	espin	parallel actin filament bundle assembly	Biological process	-
TRAK2	66008	trafficking protein, kinesin binding 2	GABA receptor binding	Molecular function	15644324
MAPK13	5603	mitogen-activated protein kinase 13	MAP kinase activity	Molecular function	9218798
ETV1	2115	ets variant 1	mechanosensory behavior	Biological process	-
GPR87	53836	G protein-coupled receptor 87	G-protein coupled receptor signaling pathway	Biological process	-
THBS1	7057	thrombospondin 1	engulfment of apoptotic cell	Biological process	16882710
CHL1	10752	cell adhesion molecule L1-like	negative regulation of neuron apoptotic process	Biological process	-
PML	5371	promyelocytic leukemia	protein binding	Molecular function	10597310
WNT7B	7477	wingless-type MMTV integration site family, member 7B	positive regulation of JNK cascade	Biological process	-
GLYAT	10249	glycine-N-acyltransferase	extracellular exosome	Cellular component	23376485
MED7	9443	mediator complex subunit 7	RNA polymerase II transcription cofactor activity	Molecular function	-
ATP6V1B1	525	ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1	hydrogen ion transmembrane transporter activity	Molecular function	14585495
POLA1	5422	polymerase (DNA directed), alpha 1, catalytic subunit	double-strand break repair via nonhomologous end joining	Biological process	11470886
CS	1431	citrate synthase	carbohydrate metabolic process	Biological process	9543345
SERAC1	84947	serine active site containing 1	endoplasmic reticulum	Cellular component	-
KIAA1462	57608	KIAA1462	adherens junction	Cellular component	-
ST3GAL1	6482	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	cellular protein modification process	Biological process	10504389
ATG4A	115201	autophagy related 4A, cysteine peptidase	cysteine-type peptidase activity	Molecular function	12473658
CD79B	974	CD79b molecule, immunoglobulin-associated beta	protein binding	Molecular function	25416956
LAMA1	284217	laminin, alpha 1	extracellular region	Cellular component	-
CREB3L2	64764	cAMP responsive element binding protein 3-like 2	endoplasmic reticulum membrane	Cellular component	-
TBXA2R	6915	thromboxane A2 receptor	plasma membrane	Cellular component	-
GATA5	140628	GATA binding protein 5	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity	Molecular function	-
VPS53	55275	vacuolar protein sorting 53 homolog (S. cerevisiae)	perinuclear region of cytoplasm	Cellular component	15878329
MLPH	79083	melanophilin	microtubule plus-end binding	Molecular function	-
MPC2	25874	mitochondrial pyruvate carrier 2	mitochondrial inner membrane	Cellular component	-
TXNIP	10628	thioredoxin interacting protein	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	Biological process	-
CRMP1	1400	collapsin response mediator protein 1	microtubule cytoskeleton organization	Biological process	-
ERBB2	2064	erb-b2 receptor tyrosine kinase 2	receptor signaling protein tyrosine kinase activity	Molecular function	-
MTMR3	8897	myotubularin related protein 3	protein serine/threonine phosphatase activity	Molecular function	10733931
FABP7	2173	fatty acid binding protein 7, brain	nervous system development	Biological process	9375786
MCM7	4176	minichromosome maintenance complex component 7	DNA replication	Biological process	-
FIGF	2277	c-fos induced growth factor (vascular endothelial growth factor D)	positive regulation of cell proliferation	Biological process	-
HSPA1B	3304	heat shock 70kDa protein 1B	nucleus	Cellular component	10205060
TAF10	6881	TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa	perinuclear region of cytoplasm	Cellular component	15870280
CRYAB	1410	crystallin, alpha B	Golgi apparatus	Cellular component	-
MAP2K6	5608	mitogen-activated protein kinase kinase 6	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	Biological process	-
PIK3CD	5293	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	inflammatory response	Biological process	17290298
TH	7054	tyrosine hydroxylase	sphingolipid metabolic process	Biological process	-
TBRG1	84897	transforming growth factor beta regulator 1	nucleolus to nucleoplasm transport	Biological process	17110379
BNC1	646	basonuclin 1	positive regulation of epithelial cell proliferation	Biological process	-
GLIS1	148979	GLIS family zinc finger 1	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	-
AAMP	14	angio-associated, migratory cell protein	cell differentiation	Biological process	-
NCOA1	8648	nuclear receptor coactivator 1	ovulation cycle	Biological process	-
SORBS3	10174	sorbin and SH3 domain containing 3	cytoskeleton	Cellular component	-
KLC1	3831	kinesin light chain 1	microtubule motor activity	Molecular function	-
LY86	9450	lymphocyte antigen 86	plasma membrane	Cellular component	9763566
EIF5B	9669	eukaryotic translation initiation factor 5B	nucleus	Cellular component	12426392
TP63	8626	tumor protein p63	positive regulation of osteoblast differentiation	Biological process	22521434
USP9Y	8287	ubiquitin specific peptidase 9, Y-linked	cysteine-type endopeptidase activity	Molecular function	-
TRIP10	9322	thyroid hormone receptor interactor 10	intracellular membrane-bounded organelle	Cellular component	-
TOPBP1	11073	topoisomerase (DNA) II binding protein 1	cytoplasm	Cellular component	-
RPS12	6206	ribosomal protein S12	membrane	Cellular component	19946888
ENOX1	55068	ecto-NOX disulfide-thiol exchanger 1	protein binding	Molecular function	25416956
MAVS	57506	mitochondrial antiviral signaling protein	positive regulation of interferon-beta production	Biological process	19609254
FHIT	2272	fragile histidine triad	intrinsic apoptotic signaling pathway by p53 class mediator	Biological process	15313915
POU2F1	5451	POU class 2 homeobox 1	gene expression	Biological process	-
CXCL9	4283	chemokine (C-X-C motif) ligand 9	response to lipopolysaccharide	Biological process	-
GIMAP2	26157	GTPase, IMAP family member 2	lipid particle	Cellular component	23454188
NOC4L	79050	nucleolar complex associated 4 homolog (S. cerevisiae)	Noc4p-Nop14p complex	Cellular component	-
YWHAB	7529	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta	negative regulation of transcription, DNA-templated	Biological process	-
VIMP	55829	VCP-interacting membrane selenoprotein	ER overload response	Biological process	17210132
NDUFA8	4702	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa	mitochondrion	Cellular component	-
AP2A1	160	adaptor-related protein complex 2, alpha 1 subunit	Golgi to endosome transport	Biological process	12036598
ZBTB7B	51043	zinc finger and BTB domain containing 7B	sequence-specific DNA binding RNA polymerase II transcription factor activity	Molecular function	-
SC5D	6309	sterol-C5-desaturase	lathosterol oxidase activity	Molecular function	-
ADK	132	adenosine kinase	ribonucleoside monophosphate biosynthetic process	Biological process	9070863
NDUFV2	4729	NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa	cardiac muscle tissue development	Biological process	12754703
DDOST	1650	dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)	dolichyl-diphosphooligosaccharide-protein glycotransferase activity	Molecular function	9642163
SLC6A14	11254	solute carrier family 6 (amino acid transporter), member 14	transmembrane transport	Biological process	-
ATP6V0E2	155066	ATPase, H+ transporting V0 subunit e2	ion transmembrane transport	Biological process	-
CACTIN	58509	cactin, spliceosome C complex subunit	cellular response to lipopolysaccharide	Biological process	20829348
CLUAP1	23059	clusterin associated protein 1	intraciliary transport particle B	Cellular component	-
IL4	3565	interleukin 4	response to organic cyclic compound	Biological process	-
AQP1	358	aquaporin 1 (Colton blood group)	water transport	Biological process	-
TPH2	121278	tryptophan hydroxylase 2	cellular nitrogen compound metabolic process	Biological process	-
CLU	1191	clusterin	positive regulation of neurofibrillary tangle assembly	Biological process	15897157
HIST1H2AD	3013	histone cluster 1, H2ad	protein heterodimerization activity	Molecular function	-
ATP6V1C2	245973	ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2	extracellular exosome	Cellular component	19056867
PDK2	5164	pyruvate dehydrogenase kinase, isozyme 2	cytoplasm	Cellular component	-
TRIM56	81844	tripartite motif containing 56	defense response to virus	Biological process	-
NUP188	23511	nucleoporin 188kDa	mitotic nuclear envelope disassembly	Biological process	-
SPAG16	79582	sperm associated antigen 16	microtubule cytoskeleton	Cellular component	-
CTNNA1	1495	catenin (cadherin-associated protein), alpha 1, 102kDa	male gonad development	Biological process	-
DRD3	1814	dopamine receptor D3	D1 dopamine receptor binding	Molecular function	-
HIST1H4E	8367	histone cluster 1, H4e	extracellular region	Cellular component	-
NOS3	4846	nitric oxide synthase 3 (endothelial cell)	nitric oxide metabolic process	Biological process	-
TREML2	79865	triggering receptor expressed on myeloid cells-like 2	plasma membrane	Cellular component	-
KLK8	11202	kallikrein-related peptidase 8	synapse organization	Biological process	-
FLAD1	80308	flavin adenine dinucleotide synthetase 1	vitamin metabolic process	Biological process	-
FGF17	8822	fibroblast growth factor 17	extracellular space	Cellular component	9514906
NR1H2	7376	nuclear receptor subfamily 1, group H, member 2	nucleoplasm	Cellular component	-
EPO	2056	erythropoietin	response to hyperoxia	Biological process	-
SNAP23	8773	synaptosomal-associated protein, 23kDa	syntaxin binding	Molecular function	16677249
RAB6A	5870	RAB6A, member RAS oncogene family	antigen processing and presentation	Biological process	19717423
LMX1B	4010	LIM homeobox transcription factor 1, beta	dopaminergic neuron differentiation	Biological process	-
C2CD5	9847	C2 calcium-dependent domain containing 5	vesicle fusion	Biological process	-
KRT28	162605	keratin 28, type I	structural molecule activity	Molecular function	-
ADCY6	112	adenylate cyclase 6	adenylate cyclase-activating G-protein coupled receptor signaling pathway	Biological process	-
A4GNT	51146	alpha-1,4-N-acetylglucosaminyltransferase	integral component of membrane	Cellular component	-
SCN4A	6329	sodium channel, voltage gated, type IV alpha subunit	sodium ion transmembrane transport	Biological process	-
SCYL1	57410	SCY1-like 1 (S. cerevisiae)	microtubule organizing center	Cellular component	-
RELA	5970	v-rel avian reticuloendotheliosis viral oncogene homolog A	Fc-epsilon receptor signaling pathway	Biological process	-
SORBS1	10580	sorbin and SH3 domain containing 1	positive regulation of lipid biosynthetic process	Biological process	11001060
MAP3K5	4217	mitogen-activated protein kinase kinase kinase 5	activation of JUN kinase activity	Biological process	8974401
RUVBL1	8607	RuvB-like AAA ATPase 1	histone H4 acetylation	Biological process	14966270
PTPN5	84867	protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)	peptidyl-tyrosine dephosphorylation	Biological process	7490079
ADD1	118	adducin 1 (alpha)	in utero embryonic development	Biological process	-
GATA2	2624	GATA binding protein 2	commitment of neuronal cell to specific neuron type in forebrain	Biological process	-
BBS2	583	Bardet-Biedl syndrome 2	hippocampus development	Biological process	-
CAPRIN2	65981	caprin family member 2	negative regulation of translation	Biological process	-
SETD8	387893	SET domain containing (lysine methyltransferase) 8	nucleolus	Cellular component	-
CD63	967	CD63 molecule	late endosome membrane	Cellular component	23632027
NR1H2	7376	nuclear receptor subfamily 1, group H, member 2	negative regulation of lipid transport	Biological process	17693624
NEK2	4751	NIMA-related kinase 2	mitotic cell cycle	Biological process	-
TGFB3	7043	transforming growth factor, beta 3	T-tubule	Cellular component	-
HSPA6	3310	heat shock 70kDa protein 6 (HSP70B')	unfolded protein binding	Molecular function	21231916
DEFB132	400830	defensin, beta 132	innate immune response	Biological process	-
MADD	8567	MAP-kinase activating death domain	positive regulation of GTPase activity	Biological process	9115275
RAD18	56852	RAD18 E3 ubiquitin protein ligase	ubiquitin protein ligase binding	Molecular function	10908344
NR2F2	7026	nuclear receptor subfamily 2, group F, member 2	lipid metabolic process	Biological process	1899293
MECR	51102	mitochondrial trans-2-enoyl-CoA reductase	fatty acid metabolic process	Biological process	12654921
PSEN2	5664	presenilin 2	endoplasmic reticulum calcium ion homeostasis	Biological process	-
ZYX	7791	zyxin	cell-matrix adhesion	Biological process	24036928
RBM6	10180	RNA binding motif protein 6	DNA binding	Molecular function	10352938
CLIP1	6249	CAP-GLY domain containing linker protein 1	ruffle	Cellular component	-
HIF1AN	55662	hypoxia inducible factor 1, alpha subunit inhibitor	positive regulation of vasculogenesis	Biological process	17636018
PRKD2	25865	protein kinase D2	positive regulation of NF-kappaB transcription factor activity	Biological process	15604256
DGKZ	8525	diacylglycerol kinase, zeta	negative regulation of catalytic activity	Biological process	-
FBXO2	26232	F-box protein 2	cellular protein modification process	Biological process	10531035
NSA2	10412	NSA2 ribosome biogenesis homolog (S. cerevisiae)	rRNA processing	Biological process	-
TRAK2	66008	trafficking protein, kinesin binding 2	nucleus	Cellular component	-
MAVS	57506	mitochondrial antiviral signaling protein	mitochondrion	Cellular component	-
BECN1	8678	beclin 1, autophagy related	negative regulation of apoptotic process	Biological process	9765397
CCNB1	891	cyclin B1	mitotic spindle stabilization	Biological process	18195732
EEF1A1	1915	eukaryotic translation elongation factor 1 alpha 1	translation	Biological process	-
KDM6A	7403	lysine (K)-specific demethylase 6A	regulation of gene expression	Biological process	-
WNT10B	7480	wingless-type MMTV integration site family, member 10B	hematopoietic stem cell proliferation	Biological process	9787155
NRIP1	8204	nuclear receptor interacting protein 1	transcription coactivator activity	Molecular function	15572661
FASN	2194	fatty acid synthase	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity	Molecular function	-
MYDGF	56005	myeloid-derived growth factor	positive regulation of protein kinase B signaling	Biological process	-
TAB1	10454	TGF-beta activated kinase 1/MAP3K7 binding protein 1	toll-like receptor TLR1:TLR2 signaling pathway	Biological process	-
TRIM21	6737	tripartite motif containing 21	positive regulation of viral entry into host cell	Biological process	-
ATR	545	ATR serine/threonine kinase	cellular response to gamma radiation	Biological process	9925639
PLEKHA2	59339	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2	positive regulation of cell-matrix adhesion	Biological process	19786618
TIGIT	201633	T cell immunoreceptor with Ig and ITIM domains	receptor binding	Molecular function	19011627
TAF10	6881	TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa	transcription initiation from RNA polymerase II promoter	Biological process	-
NFKBIB	4793	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	toll-like receptor TLR1:TLR2 signaling pathway	Biological process	-
PZP	5858	pregnancy-zone protein	extracellular exosome	Cellular component	21362503
MAFF	23764	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F	in utero embryonic development	Biological process	-
MRGBP	55257	MRG/MORF4L binding protein	protein binding	Molecular function	12963728
APOA4	337	apolipoprotein A-IV	lipid transporter activity	Molecular function	3080432
SFMBT2	57713	Scm-like with four mbt domains 2	intracellular membrane-bounded organelle	Cellular component	-
HEY1	23462	hes-related family bHLH transcription factor with YRPW motif 1	arterial endothelial cell differentiation	Biological process	-
GNAQ	2776	guanine nucleotide binding protein (G protein), q polypeptide	maternal behavior	Biological process	-
GAPDH	2597	glyceraldehyde-3-phosphate dehydrogenase	intracellular membrane-bounded organelle	Cellular component	-
TBCE	6905	tubulin folding cofactor E	cytoplasm	Cellular component	-
ADM	133	adrenomedullin	response to wounding	Biological process	-
OR6K3	391114	olfactory receptor, family 6, subfamily K, member 3	G-protein coupled receptor activity	Molecular function	-
PPP1R42	286187	protein phosphatase 1, regulatory subunit 42	manchette	Cellular component	-
CD40LG	959	CD40 ligand	B cell differentiation	Biological process	-
OR9Q2	219957	olfactory receptor, family 9, subfamily Q, member 2	olfactory receptor activity	Molecular function	-
SLC4A1	6521	solute carrier family 4 (anion exchanger), member 1 (Diego blood group)	chloride transmembrane transport	Biological process	-
GLS	2744	glutaminase	protein homotetramerization	Biological process	22049910
BHLHA9	727857	basic helix-loop-helix family, member a9	cytoplasm	Cellular component	25466284
PAX2	5076	paired box 2	cellular response to epidermal growth factor stimulus	Biological process	-
WWC1	23286	WW and C2 domain containing 1	cell migration	Biological process	18596123
DAG1	1605	dystroglycan 1 (dystrophin-associated glycoprotein 1)	dystroglycan complex	Cellular component	-
NPC1L1	29881	NPC1-like 1	integral component of membrane	Cellular component	19325169
ZNF75A	7627	zinc finger protein 75a	regulation of transcription, DNA-templated	Biological process	-
AACS	65985	acetoacetyl-CoA synthetase	positive regulation of insulin secretion	Biological process	-
DNMT3L	29947	DNA (cytosine-5-)-methyltransferase 3-like	regulation of gene expression by genetic imprinting	Biological process	12202768
USH1C	10083	Usher syndrome 1C (autosomal recessive, severe)	stereocilium	Cellular component	16464467
REST	5978	RE1-silencing transcription factor	core promoter binding	Molecular function	17984088
ENAH	55740	enabled homolog (Drosophila)	filopodium	Cellular component	-
GCK	2645	glucokinase (hexokinase 4)	second-messenger-mediated signaling	Biological process	-
TMED10	10972	transmembrane emp24-like trafficking protein 10 (yeast)	zymogen granule membrane	Cellular component	-
KLK12	43849	kallikrein-related peptidase 12	extracellular space	Cellular component	21628462
NPHP4	261734	nephronophthisis 4	photoreceptor cell outer segment organization	Biological process	-
PRKACA	5566	protein kinase, cAMP-dependent, catalytic, alpha	extracellular exosome	Cellular component	23376485
ATG16L1	55054	autophagy related 16-like 1 (S. cerevisiae)	autophagosome assembly	Biological process	15620219
ZMAT1	84460	zinc finger, matrin-type 1	nucleus	Cellular component	-
TUBB4B	10383	tubulin, beta 4B class IVb	mitotic cell cycle	Biological process	-
OR9G4	283189	olfactory receptor, family 9, subfamily G, member 4	sensory perception of smell	Biological process	-
P2RX4	5025	purinergic receptor P2X, ligand gated ion channel, 4	cation transport	Biological process	-
FNBP1	23048	formin binding protein 1	coated pit	Cellular component	-
RPL27	6155	ribosomal protein L27	translation	Biological process	-
RAB40C	57799	RAB40C, member RAS oncogene family	protein ubiquitination	Biological process	-
TRAF2	7186	TNF receptor-associated factor 2	positive regulation of T cell cytokine production	Biological process	15125833
OR13G1	441933	olfactory receptor, family 13, subfamily G, member 1	transmembrane signaling receptor activity	Molecular function	-
ADI1	55256	acireductone dioxygenase 1	L-methionine biosynthetic process from methylthioadenosine	Biological process	-
ZNF708	7562	zinc finger protein 708	DNA binding	Molecular function	-
AATF	26574	apoptosis antagonizing transcription factor	nucleus	Cellular component	-
UBE2V1	7335	ubiquitin-conjugating enzyme E2 variant 1	regulation of transcription, DNA-templated	Biological process	9305758
C1orf185	284546	chromosome 1 open reading frame 185	integral component of membrane	Cellular component	-
CNGB3	54714	cyclic nucleotide gated channel beta 3	signal transduction	Biological process	10888875
KCNJ11	3767	potassium channel, inwardly rectifying subfamily J, member 11	integral component of plasma membrane	Cellular component	8923010
STAT5A	6776	signal transducer and activator of transcription 5A	development of secondary male sexual characteristics	Biological process	-
MTMR2	8898	myotubularin related protein 2	protein tetramerization	Biological process	-
C10orf54	64115	chromosome 10 open reading frame 54	negative regulation of T cell cytokine production	Biological process	-
DHCR24	1718	24-dehydrocholesterol reductase	delta24(24-1) sterol reductase activity	Molecular function	11519011
CA2	760	carbonic anhydrase II	arylesterase activity	Molecular function	3126084
ANGPT1	284	angiopoietin 1	protein binding	Molecular function	25814554
ABCF1	23	ATP-binding cassette, sub-family F (GCN20), member 1	translation factor activity, RNA binding	Molecular function	9790762
ADGRF2	222611	adhesion G protein-coupled receptor F2	plasma membrane	Cellular component	-
SEC22A	26984	SEC22 vesicle trafficking protein homolog A (S. cerevisiae)	protein transport	Biological process	-
CLU	1191	clusterin	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	Biological process	16113678
SCN5A	6331	sodium channel, voltage gated, type V alpha subunit	AV node cell to bundle of His cell communication	Biological process	10471492
IGKV3D-20	28874	immunoglobulin kappa variable 3D-20	complement activation, classical pathway	Biological process	-
UBA52	7311	ubiquitin A-52 residue ribosomal protein fusion product 1	error-free translesion synthesis	Biological process	-
FEZ2	9637	fasciculation and elongation protein zeta 2 (zygin II)	nervous system development	Biological process	9096408
SP7	121340	Sp7 transcription factor	metal ion binding	Molecular function	-
PAOX	196743	polyamine oxidase (exo-N4-amino)	cellular nitrogen compound metabolic process	Biological process	-
MBD5	55777	methyl-CpG binding domain protein 5	glucose homeostasis	Biological process	-
CDKN1C	1028	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	multicellular organism growth	Biological process	-
BMP1	649	bone morphogenetic protein 1	proteolysis	Biological process	16824737
PNPLA1	285848	patatin-like phospholipase domain containing 1	cytoplasm	Cellular component	22246504
ATP1B3	483	ATPase, Na+/K+ transporting, beta 3 polypeptide	transport	Biological process	8798450
DBF4B	80174	DBF4 zinc finger B	protein kinase activator activity	Molecular function	12065429
LEP	3952	leptin	cytoplasm	Cellular component	-
RBBP6	5930	retinoblastoma binding protein 6	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	18851979
ORM2	5005	orosomucoid 2	extracellular exosome	Cellular component	23533145
TFAP2D	83741	transcription factor AP-2 delta (activating enhancer binding protein 2 delta)	regulation of transcription from RNA polymerase II promoter	Biological process	-
AJUBA	84962	ajuba LIM protein	positive regulation of MAP kinase activity	Biological process	-
SOX11	6664	SRY (sex determining region Y)-box 11	lens morphogenesis in camera-type eye	Biological process	-
GATA1	2623	GATA binding protein 1 (globin transcription factor 1)	transcriptional repressor complex	Cellular component	15920471
ADAM10	102	ADAM metallopeptidase domain 10	membrane	Cellular component	19946888
GIMAP5	55340	GTPase, IMAP family member 5	positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	Biological process	-
STAU2	27067	staufen double-stranded RNA binding protein 2	transport	Biological process	-
ANXA3	306	annexin A3	positive regulation of sequence-specific DNA binding transcription factor activity	Biological process	16236264
SIAH1	6477	siah E3 ubiquitin protein ligase 1	cell cycle	Biological process	-
APOE	348	apolipoprotein E	negative regulation of endothelial cell proliferation	Biological process	9685360
DMPK	1760	dystrophia myotonica-protein kinase	nuclear membrane	Cellular component	-
JMY	133746	junction mediating and regulatory protein, p53 cofactor	nucleoplasm	Cellular component	-
GEMIN4	50628	gem (nuclear organelle) associated protein 4	SMN complex	Cellular component	18984161
RPS6KA6	27330	ribosomal protein S6 kinase, 90kDa, polypeptide 6	ATP binding	Molecular function	-
ANO1	55107	anoctamin 1, calcium activated chloride channel	transmembrane transport	Biological process	-
PPP1R11	6992	protein phosphatase 1, regulatory (inhibitor) subunit 11	negative regulation of phosphoprotein phosphatase activity	Biological process	-
SIGLEC14	100049587	sialic acid binding Ig-like lectin 14	cell adhesion	Biological process	-
HSPA1A	3303	heat shock 70kDa protein 1A	protein binding	Molecular function	12853476
PFKL	5211	phosphofructokinase, liver	protein homotetramerization	Biological process	-
ZBTB46	140685	zinc finger and BTB domain containing 46	negative regulation of granulocyte differentiation	Biological process	-
DPYSL2	1808	dihydropyrimidinase-like 2	protein binding	Molecular function	16260607
ANKRD23	200539	ankyrin repeat domain 23	actin cytoskeleton	Cellular component	-
DIRAS3	9077	DIRAS family, GTP-binding RAS-like 3	GTP binding	Molecular function	-
SLBP	7884	stem-loop binding protein	histone pre-mRNA DCP binding	Molecular function	-
CD40	958	CD40 molecule, TNF receptor superfamily member 5	positive regulation of tyrosine phosphorylation of Stat1 protein	Biological process	21410936
GOLGA2	2801	golgin A2	Golgi membrane	Cellular component	-
CRABP1	1381	cellular retinoic acid binding protein 1	retinoid binding	Molecular function	1309505
CTSB	1508	cathepsin B	cellular response to thyroid hormone stimulus	Biological process	21217776
RHOT1	55288	ras homolog family member T1	mitochondrial outer membrane permeabilization	Biological process	12482879
CYP11A1	1583	cytochrome P450, family 11, subfamily A, polypeptide 1	vitamin D metabolic process	Biological process	-
FAHD2B	151313	fumarylacetoacetate hydrolase domain containing 2B	hydrolase activity	Molecular function	-
ROCK2	9475	Rho-associated, coiled-coil containing protein kinase 2	centrosome duplication	Biological process	17015463
FAM50A	9130	family with sequence similarity 50, member A	poly(A) RNA binding	Molecular function	22681889
SMAD7	4092	SMAD family member 7	regulation of activin receptor signaling pathway	Biological process	16720724
NAF1	92345	nuclear assembly factor 1 ribonucleoprotein	cytoplasm	Cellular component	-
TMEM79	84283	transmembrane protein 79	epithelial cell maturation	Biological process	-
ZEB2	9839	zinc finger E-box binding homeobox 2	cell proliferation in forebrain	Biological process	-
NR5A2	2494	nuclear receptor subfamily 5, group A, member 2	phospholipid binding	Molecular function	15723037
SLC3A2	6520	solute carrier family 3 (amino acid transporter heavy chain), member 2	sodium ion transmembrane transport	Biological process	10673541
UBE2S	27338	ubiquitin-conjugating enzyme E2S	cell division	Biological process	-
SLFN5	162394	schlafen family member 5	nucleus	Cellular component	-
MAP1A	4130	microtubule-associated protein 1A	positive regulation of defense response to virus by host	Biological process	22020285
MOS	4342	v-mos Moloney murine sarcoma viral oncogene homolog	MAP kinase kinase kinase activity	Molecular function	-
PSEN1	5663	presenilin 1	dorsal/ventral neural tube patterning	Biological process	-
ERN2	10595	endoplasmic reticulum to nucleus signaling 2	endonuclease activity	Molecular function	11175748
MECP2	4204	methyl CpG binding protein 2	ventricular system development	Biological process	-
NCF1	653361	neutrophil cytosolic factor 1	vascular endothelial growth factor receptor signaling pathway	Biological process	-
TRPM6	140803	transient receptor potential cation channel, subfamily M, member 6	protein binding	Molecular function	18258429
FMR1	2332	fragile X mental retardation 1	nucleoplasm	Cellular component	10888599
TFAP2B	7021	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	protein dimerization activity	Molecular function	12072434
VRK1	7443	vaccinia related kinase 1	cell division	Biological process	-
SLC38A4	55089	solute carrier family 38, member 4	transmembrane transport	Biological process	-
HINFP	25988	histone H4 transcription factor	establishment of protein localization	Biological process	15988025
RPS19	6223	ribosomal protein S19	poly(A) RNA binding	Molecular function	22681889
NUP133	55746	nucleoporin 133kDa	condensed chromosome kinetochore	Cellular component	17098863
SLC2A2	6514	solute carrier family 2 (facilitated glucose transporter), member 2	glucose transport	Biological process	-
MIEF1	54471	mitochondrial elongation factor 1	protein binding	Molecular function	16189514
BOD1L2	284257	biorientation of chromosomes in cell division 1-like 2	condensed chromosome kinetochore	Cellular component	-
CXCR2	3579	chemokine (C-X-C motif) receptor 2	interleukin-8-mediated signaling pathway	Biological process	10820279
UBB	7314	ubiquitin B	seminiferous tubule development	Biological process	-
RAB11B	9230	RAB11B, member RAS oncogene family	regulation of endocytic recycling	Biological process	-
MAP7D1	55700	MAP7 domain containing 1	microtubule cytoskeleton	Cellular component	-
NLRP3	114548	NLR family, pyrin domain containing 3	ATP binding	Molecular function	-
LFNG	3955	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	integral component of Golgi membrane	Cellular component	-
ICOS	29851	inducible T-cell co-stimulator	plasma membrane	Cellular component	-
SYNJ1	8867	synaptojanin 1	synaptic vesicle uncoating	Biological process	-
NUDT4	11163	nudix (nucleoside diphosphate linked moiety X)-type motif 4	metal ion binding	Molecular function	-
FEN1	2237	flap structure-specific endonuclease 1	5'-flap endonuclease activity	Molecular function	11986308
HMGB2	3148	high mobility group box 2	damaged DNA binding	Molecular function	8226934
NT5E	4907	5'-nucleotidase, ecto (CD73)	5'-nucleotidase activity	Molecular function	7595232
GNAO1	2775	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O	GTPase activity	Molecular function	-
ROR2	4920	receptor tyrosine kinase-like orphan receptor 2	embryonic genitalia morphogenesis	Biological process	-
APOA1	335	apolipoprotein A-I	negative regulation of cell adhesion molecule production	Biological process	21571275
IL1B	3553	interleukin 1, beta	positive regulation of phagocytosis	Biological process	18201371
HOOK3	84376	hook microtubule-tethering protein 3	Golgi apparatus	Cellular component	-
ANKRD1	27063	ankyrin repeat domain 1 (cardiac muscle)	RNA polymerase II transcription coactivator activity	Molecular function	20599664
FLT3	2322	fms-related tyrosine kinase 3	B cell differentiation	Biological process	-
SNRPGP15	100130932	small nuclear ribonucleoprotein polypeptide G pseudogene 15	spliceosomal complex	Cellular component	-
CHMP2B	25978	charged multivesicular body protein 2B	viral life cycle	Biological process	-
ANXA5	308	annexin A5	external side of plasma membrane	Cellular component	-
UBR3	130507	ubiquitin protein ligase E3 component n-recognin 3 (putative)	ubiquitin ligase complex	Cellular component	-
ZNRD1	30834	zinc ribbon domain containing 1	negative regulation of gene expression, epigenetic	Biological process	-
IFT74	80173	intraflagellar transport 74	Notch signaling pathway	Biological process	-
NPFF	8620	neuropeptide FF-amide peptide precursor	regulation of membrane depolarization	Biological process	-
NCAM2	4685	neural cell adhesion molecule 2	plasma membrane	Cellular component	-
HFE2	148738	hemochromatosis type 2 (juvenile)	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
ARHGEF2	9181	Rho/Rac guanine nucleotide exchange factor (GEF) 2	protein complex	Cellular component	21887730
NCF1	653361	neutrophil cytosolic factor 1	phosphatidylinositol-3,4-bisphosphate binding	Molecular function	12356722
CTCFL	140690	CCCTC-binding factor (zinc finger protein)-like	DNA binding	Molecular function	18413740
EPB41L5	57669	erythrocyte membrane protein band 4.1 like 5	neural plate morphogenesis	Biological process	-
CBS	875	cystathionine-beta-synthase	metal ion binding	Molecular function	-
DUSP14	11072	dual specificity phosphatase 14	poly(A) RNA binding	Molecular function	22681889
TPM1	7168	tropomyosin 1 (alpha)	cytoskeleton	Cellular component	16130169
LRIF1	55791	ligand dependent nuclear receptor interacting factor 1	regulation of transcription, DNA-templated	Biological process	-
WASL	8976	Wiskott-Aldrich syndrome-like	small GTPase mediated signal transduction	Biological process	-
FAIM2	23017	Fas apoptotic inhibitory molecule 2	negative regulation of neuron apoptotic process	Biological process	-
FBXW5	54461	F-box and WD repeat domain containing 5	mitotic nuclear division	Biological process	-
JUN	3725	jun proto-oncogene	regulation of cell death	Biological process	-
CADM1	23705	cell adhesion molecule 1	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	Biological process	12826663
ARID4A	5926	AT rich interactive domain 4A (RBP1-like)	histone H3-K4 trimethylation	Biological process	-
SFRP4	6424	secreted frizzled-related protein 4	cell surface	Cellular component	14760084
PAK2	5062	p21 protein (Cdc42/Rac)-activated kinase 2	stimulatory C-type lectin receptor signaling pathway	Biological process	-
DMTN	2039	dematin actin binding protein	protein binding	Molecular function	18347014
TMEM115	11070	transmembrane protein 115	protein binding	Molecular function	24806965
KLRG2	346689	killer cell lectin-like receptor subfamily G, member 2	carbohydrate binding	Molecular function	-
ARAP1	116985	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1	type 1 angiotensin receptor binding	Molecular function	-
ZFHX4	79776	zinc finger homeobox 4	regulation of transcription, DNA-templated	Biological process	-
UBE2D1	7321	ubiquitin-conjugating enzyme E2D 1	cellular response to hypoxia	Biological process	-
CETP	1071	cholesteryl ester transfer protein, plasma	high-density lipoprotein particle	Cellular component	3104518
PIP4K2A	5305	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	ATP binding	Molecular function	-
MARK2	2011	MAP/microtubule affinity-regulating kinase 2	microtubule bundle	Cellular component	23902687
BTRC	8945	beta-transducin repeat containing E3 ubiquitin protein ligase	protein dimerization activity	Molecular function	-
PI4KB	5298	phosphatidylinositol 4-kinase, catalytic, beta	endosome	Cellular component	9584208
TAS2R43	259289	taste receptor, type 2, member 43	taste receptor activity	Molecular function	16720576
SNX3	8724	sorting nexin 3	protein to membrane docking	Biological process	24344282
CAV3	859	caveolin 3	positive regulation of microtubule polymerization	Biological process	-
TBC1D30	23329	TBC1 domain family, member 30	plasma membrane	Cellular component	-
CCDC88A	55704	coiled-coil domain containing 88A	cell migration	Biological process	16139227
SULT1C3	442038	sulfotransferase family, cytosolic, 1C, member 3	cytoplasm	Cellular component	-
ANXA6	309	annexin A6	focal adhesion	Cellular component	21423176
SIX3	6496	SIX homeobox 3	lens fiber cell apoptotic process	Biological process	-
MUSTN1	389125	musculoskeletal, embryonic nuclear protein 1	nucleus	Cellular component	-
EREG	2069	epiregulin	luteinizing hormone signaling pathway	Biological process	-
MICU1	10367	mitochondrial calcium uptake 1	mitochondrion	Cellular component	-
NBEAL2	23218	neurobeachin-like 2	endomembrane system	Cellular component	-
AQP9	366	aquaporin 9	polyol transport	Biological process	9733774
DCPS	28960	decapping enzyme, scavenger	deadenylation-dependent decapping of nuclear-transcribed mRNA	Biological process	-
CD160	11126	CD160 molecule	anchored component of plasma membrane	Cellular component	9973372
PRSS27	83886	protease, serine 27	proteolysis	Biological process	-
PRM3	58531	protamine 3	chromosome condensation	Biological process	-
SNRPE	6635	small nuclear ribonucleoprotein polypeptide E	U1 snRNP	Cellular component	21113136
ITGA6	3655	integrin, alpha 6	amelogenesis	Biological process	23496044
SOX4	6659	SRY (sex determining region Y)-box 4	glucose homeostasis	Biological process	-
UBE2I	7329	ubiquitin-conjugating enzyme E2I	positive regulation of SUMO transferase activity	Biological process	19955185
IFNE	338376	interferon, epsilon	cytokine-mediated signaling pathway	Biological process	-
HAP1	9001	huntingtin-associated protein 1	protein transport	Biological process	-
MSX2	4488	msh homeobox 2	osteoblast differentiation	Biological process	-
TCL1A	8115	T-cell leukemia/lymphoma 1A	multicellular organismal development	Biological process	7809072
MKX	283078	mohawk homeobox	tendon sheath development	Biological process	-
RPS6	6194	ribosomal protein S6	translation	Biological process	-
PEX14	5195	peroxisomal biogenesis factor 14	protein import into peroxisome matrix, substrate release	Biological process	21976670
KIR2DL3	3804	killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3	integral component of plasma membrane	Cellular component	9059894
FMN2	56776	formin 2	cytoplasmic vesicle membrane	Cellular component	-
SOX4	6659	SRY (sex determining region Y)-box 4	cardiac right ventricle morphogenesis	Biological process	-
GPR87	53836	G protein-coupled receptor 87	G-protein coupled purinergic nucleotide receptor signaling pathway	Biological process	-
THOC5	8563	THO complex 5	cell morphogenesis	Biological process	-
PIM3	415116	Pim-3 proto-oncogene, serine/threonine kinase	histone phosphorylation	Biological process	-
GCG	2641	glucagon	protein binding	Molecular function	21314817
PPP1CC	5501	protein phosphatase 1, catalytic subunit, gamma isozyme	nuclear speck	Cellular component	-
ACVRL1	94	activin A receptor type II-like 1	integral component of plasma membrane	Cellular component	8242742
LTF	4057	lactotransferrin	humoral immune response	Biological process	9770539
SOD1	6647	superoxide dismutase 1, soluble	response to axon injury	Biological process	-
DUSP22	56940	dual specificity phosphatase 22	regulation of cell proliferation	Biological process	-
DNTTIP1	116092	deoxynucleotidyltransferase, terminal, interacting protein 1	DNA binding	Molecular function	11473582
HSH2D	84941	hematopoietic SH2 domain containing	positive regulation of signal transduction	Biological process	-
RYR2	6262	ryanodine receptor 2 (cardiac)	sarcoplasmic reticulum	Cellular component	10830164
IFNA17	3451	interferon, alpha 17	response to virus	Biological process	3891272
ZBP1	81030	Z-DNA binding protein 1	positive regulation of type I interferon-mediated signaling pathway	Biological process	-
BCL2	596	B-cell CLL/lymphoma 2	response to drug	Biological process	17875758
PAAF1	80227	proteasomal ATPase-associated factor 1	proteasome complex	Cellular component	17323924
CRIM1	51232	cysteine rich transmembrane BMP regulator 1 (chordin-like)	integral component of membrane	Cellular component	-
POLR2F	5435	polymerase (RNA) II (DNA directed) polypeptide F	transcription from RNA polymerase II promoter	Biological process	-
FOLR3	2352	folate receptor 3 (gamma)	extracellular region	Cellular component	-
EIF4G3	8672	eukaryotic translation initiation factor 4 gamma, 3	regulation of translational initiation	Biological process	9418880
ZNF720	124411	zinc finger protein 720	intracellular	Cellular component	-
CTNNBIP1	56998	catenin, beta interacting protein 1	protein binding	Molecular function	12408824
SLC35A3	23443	solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3	UDP-N-acetylglucosamine transport	Biological process	23089177
OAS1	4938	2'-5'-oligoadenylate synthetase 1, 40/46kDa	protein oligomerization	Biological process	11682059
DSG3	1830	desmoglein 3	cytosol	Cellular component	-
ZNF182	7569	zinc finger protein 182	metal ion binding	Molecular function	-
DPYSL5	56896	dihydropyrimidinase-like 5	cytosol	Cellular component	-
EGF	1950	epidermal growth factor	angiogenesis	Biological process	15611079
STAG2	10735	stromal antigen 2	chromatin binding	Molecular function	-
PALLD	23022	palladin, cytoskeletal associated protein	actin filament	Cellular component	11598191
SP5	389058	Sp5 transcription factor	transcription, DNA-templated	Biological process	-
MRGPRX4	117196	MAS-related GPR, member X4	G-protein coupled receptor activity	Molecular function	-
NR2C1	7181	nuclear receptor subfamily 2, group C, member 1	sequence-specific DNA binding	Molecular function	-
GDF6	392255	growth differentiation factor 6	cytokine activity	Molecular function	-
CARD11	84433	caspase recruitment domain family, member 11	cytoplasm	Cellular component	12154360
OR4F29	729759	olfactory receptor, family 4, subfamily F, member 29	G-protein coupled receptor activity	Molecular function	-
GPKOW	27238	G patch domain and KOW motifs	molecular_function	Molecular function	-
OR5T3	390154	olfactory receptor, family 5, subfamily T, member 3	G-protein coupled receptor activity	Molecular function	-
FZD1	8321	frizzled class receptor 1	muscular septum morphogenesis	Biological process	-
SLC25A32	81034	solute carrier family 25 (mitochondrial folate carrier), member 32	mitochondrial transport	Biological process	-
APOE	348	apolipoprotein E	fatty acid homeostasis	Biological process	24345162
SLC6A4	6532	solute carrier family 6 (neurotransmitter transporter), member 4	response to drug	Biological process	-
HIST1H2BI	8346	histone cluster 1, H2bi	nucleus	Cellular component	21630459
HAUS8	93323	HAUS augmin-like complex, subunit 8	centrosome organization	Biological process	19427217
CUL7	9820	cullin 7	cellular protein metabolic process	Biological process	-
GNAO1	2775	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O	GTPase activating protein binding	Molecular function	-
SLC6A2	6530	solute carrier family 6 (neurotransmitter transporter), member 2	transport	Biological process	2008212
LMX1B	4010	LIM homeobox transcription factor 1, beta	protein binding	Molecular function	12792813
SULT2B1	6820	sulfotransferase family, cytosolic, 2B, member 1	protein binding	Molecular function	16189514
STARD13	90627	StAR-related lipid transfer (START) domain containing 13	positive regulation of GTPase activity	Biological process	-
ACTC1	70	actin, alpha, cardiac muscle 1	extracellular space	Cellular component	22664934
FLT3	2322	fms-related tyrosine kinase 3	positive regulation of MAP kinase activity	Biological process	19549778
TRIM29	23650	tripartite motif containing 29	transcription from RNA polymerase II promoter	Biological process	8188213
PRDX4	10549	peroxiredoxin 4	extracellular matrix organization	Biological process	-
MYB	4602	v-myb avian myeloblastosis viral oncogene homolog	positive regulation of histone H3-K4 methylation	Biological process	20484083
CX3CR1	1524	chemokine (C-X3-C motif) receptor 1	chemokine-mediated signaling pathway	Biological process	10754298
ASNS	440	asparagine synthetase (glutamine-hydrolyzing)	endoplasmic reticulum unfolded protein response	Biological process	-
GCK	2645	glucokinase (hexokinase 4)	endocrine pancreas development	Biological process	-
GATA1	2623	GATA binding protein 1 (globin transcription factor 1)	nucleus	Cellular component	10700180
DSG2	1829	desmoglein 2	desmosome organization	Biological process	16505173
MICALL2	79778	MICAL-like 2	actin filament bundle	Cellular component	-
SEMA3A	10371	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	semaphorin-plexin signaling pathway	Biological process	19909241
GYLTL1B	120071	glycosyltransferase-like 1B	integral component of membrane	Cellular component	-
ICT1	3396	immature colon carcinoma transcript 1	translation release factor activity, codon nonspecific	Molecular function	20186120
CLNS1A	1207	chloride channel, nucleotide-sensitive, 1A	cytoplasm	Cellular component	-
RNASE3	6037	ribonuclease, RNase A family, 3	extracellular exosome	Cellular component	23376485
IGSF1	3547	immunoglobulin superfamily, member 1	integral component of membrane	Cellular component	-
ATG2B	55102	autophagy related 2B	nucleophagy	Biological process	-
CCL3	6348	chemokine (C-C motif) ligand 3	chemokine activity	Molecular function	10072545
MTERF1	7978	mitochondrial transcription termination factor 1	double-stranded DNA binding	Molecular function	20550934
CHRNA4	1137	cholinergic receptor, nicotinic, alpha 4 (neuronal)	regulation of dopamine secretion	Biological process	-
PFN1	5216	profilin 1	platelet degranulation	Biological process	-
IGKV4-1	28908	immunoglobulin kappa variable 4-1	receptor-mediated endocytosis	Biological process	-
ACTN1	87	actinin, alpha 1	cytosol	Cellular component	-
CHST1	8534	carbohydrate (keratan sulfate Gal-6) sulfotransferase 1	keratan sulfate metabolic process	Biological process	-
MIXL1	83881	Mix paired-like homeobox	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	-
DRGX	644168	dorsal root ganglia homeobox	sensory perception of mechanical stimulus	Biological process	-
TTC9	23508	tetratricopeptide repeat domain 9	protein peptidyl-prolyl isomerization	Biological process	-
SLC25A3	5250	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3	protein complex binding	Molecular function	23209302
THY1	7070	Thy-1 cell surface antigen	membrane raft	Cellular component	15093746
RNF114	55905	ring finger protein 114	ligase activity	Molecular function	-
RPE65	6121	retinal pigment epithelium-specific protein 65kDa	endoplasmic reticulum	Cellular component	-
PTGFR	5737	prostaglandin F receptor (FP)	positive regulation of cell proliferation	Biological process	18508192
KAT6B	23522	K(lysine) acetyltransferase 6B	nucleus	Cellular component	10497217
L1RE1	4029	LINE1 retrotransposable element 1	identical protein binding	Molecular function	19139409
CRKL	1399	v-crk avian sarcoma virus CT10 oncogene homolog-like	anterior/posterior pattern specification	Biological process	-
PRCP	5547	prolylcarboxypeptidase (angiotensinase C)	serine-type carboxypeptidase activity	Molecular function	-
DDAH1	23576	dimethylarginine dimethylaminohydrolase 1	catalytic activity	Molecular function	9874257
UPF3B	65109	UPF3 regulator of nonsense transcripts homolog B (yeast)	cytoplasm	Cellular component	11163187
DNM1L	10059	dynamin 1-like	positive regulation of protein secretion	Biological process	9570752
KCNT2	343450	potassium channel, sodium activated subfamily T, member 2	potassium ion transmembrane transport	Biological process	-
UBTFL1	642623	upstream binding transcription factor, RNA polymerase I-like 1	regulation of gene expression	Biological process	-
GCGR	2642	glucagon receptor	small molecule metabolic process	Biological process	-
EIF4E	1977	eukaryotic translation initiation factor 4E	poly(A) RNA binding	Molecular function	22681889
PCIF1	63935	PDX1 C-terminal inhibiting factor 1	negative regulation of phosphatase activity	Biological process	19389623
IL2	3558	interleukin 2	cytokine activity	Molecular function	10072077
BZW1	9689	basic leucine zipper and W2 domains 1	poly(A) RNA binding	Molecular function	22658674
TMC8	147138	transmembrane channel-like 8	regulation of extrinsic apoptotic signaling pathway via death domain receptors	Biological process	23429285
ADIPOQ	9370	adiponectin, C1Q and collagen domain containing	response to tumor necrosis factor	Biological process	10604883
STAG2	10735	stromal antigen 2	plasma membrane	Cellular component	-
NAGK	55577	N-acetylglucosamine kinase	N-acetylmannosamine metabolic process	Biological process	10824116
APC	324	adenomatous polyposis coli	centrosome	Cellular component	11283619
TACR3	6870	tachykinin receptor 3	dendrite membrane	Cellular component	-
CLTB	1212	clathrin, light chain B	protein binding	Molecular function	11889126
HIST1H3F	8968	histone cluster 1, H3f	membrane	Cellular component	19946888
CACNA2D2	9254	calcium channel, voltage-dependent, alpha 2/delta subunit 2	regulation of multicellular organism growth	Biological process	-
CLU	1191	clusterin	positive regulation of apoptotic process	Biological process	21567405
LDHAL6B	92483	lactate dehydrogenase A-like 6B	carboxylic acid metabolic process	Biological process	-
GPRIN1	114787	G protein regulated inducer of neurite outgrowth 1	phosphoprotein binding	Molecular function	-
RRP8	23378	ribosomal RNA processing 8, methyltransferase, homolog (yeast)	transcription, DNA-templated	Biological process	-
RPS27A	6233	ribosomal protein S27a	transcription initiation from RNA polymerase II promoter	Biological process	-
ACVR1C	130399	activin A receptor, type IC	cell differentiation	Biological process	15531507
KRT10	3858	keratin 10, type I	nucleus	Cellular component	21630459
DAZAP1	26528	DAZ associated protein 1	cell proliferation	Biological process	-
SCARA5	286133	scavenger receptor class A, member 5	cell surface	Cellular component	-
IL6R	3570	interleukin 6 receptor	positive regulation of tyrosine phosphorylation of Stat3 protein	Biological process	12643274
MFAP3	4238	microfibrillar-associated protein 3	extracellular region	Cellular component	-
KCNK4	50801	potassium channel, two pore domain subfamily K, member 4	synaptic transmission	Biological process	-
PDLIM5	10611	PDZ and LIM domain 5	protein kinase C binding	Molecular function	-
ESCO2	157570	establishment of sister chromatid cohesion N-acetyltransferase 2	chromatin	Cellular component	19907496
PTPRE	5791	protein tyrosine phosphatase, receptor type, E	cytoplasm	Cellular component	10980613
ZBTB9	221504	zinc finger and BTB domain containing 9	transcription, DNA-templated	Biological process	-
APOBEC3C	27350	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C	zinc ion binding	Molecular function	-
ZNF154	7710	zinc finger protein 154	metal ion binding	Molecular function	-
CRHR1	1394	corticotropin releasing hormone receptor 1	parturition	Biological process	10598591
CYP39A1	51302	cytochrome P450, family 39, subfamily A, polypeptide 1	oxysterol 7-alpha-hydroxylase activity	Molecular function	10748047
UCHL3	7347	ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)	nucleus	Cellular component	-
ERI2	112479	ERI1 exoribonuclease family member 2	3'-5'-exoribonuclease activity	Molecular function	-
IFT88	8100	intraflagellar transport 88	ciliary tip	Cellular component	-
HNRNPL	3191	heterogeneous nuclear ribonucleoprotein L	RNA processing	Biological process	2687284
NUDT8	254552	nudix (nucleoside diphosphate linked moiety X)-type motif 8	metabolic process	Biological process	-
CRYBA2	1412	crystallin, beta A2	lens development in camera-type eye	Biological process	-
IFI27L1	122509	interferon, alpha-inducible protein 27-like 1	integral component of membrane	Cellular component	-
PNLIPRP2	5408	pancreatic lipase-related protein 2	galactolipid catabolic process	Biological process	18702514
ZNF207	7756	zinc finger protein 207	zinc ion binding	Molecular function	9799612
APOL2	23780	apolipoprotein L, 2	cholesterol metabolic process	Biological process	11374903
RARB	5915	retinoic acid receptor, beta	embryonic digestive tract development	Biological process	19443732
INPP5K	51763	inositol polyphosphate-5-phosphatase K	inositol-1,4,5-trisphosphate 5-phosphatase activity	Molecular function	-
SFMBT2	57713	Scm-like with four mbt domains 2	histone binding	Molecular function	23385818
MAFB	9935	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
CSF1R	1436	colony stimulating factor 1 receptor	cytokine binding	Molecular function	19017797
INSM1	3642	insulinoma-associated 1	transdifferentiation	Biological process	16511571
WNT11	7481	wingless-type MMTV integration site family, member 11	positive regulation of apoptotic process	Biological process	-
IL23A	51561	interleukin 23, alpha subunit p19	defense response to virus	Biological process	-
DLG1	1739	discs, large homolog 1 (Drosophila)	membrane raft	Cellular component	-
FAM57B	83723	family with sequence similarity 57, member B	ceramide biosynthetic process	Biological process	-
FKBP7	51661	FK506 binding protein 7	cytoplasm	Cellular component	-
SPC24	147841	SPC24, NDC80 kinetochore complex component	protein binding	Molecular function	14738735
ADCY8	114	adenylate cyclase 8 (brain)	learning or memory	Biological process	8076676
CD4	920	CD4 molecule	integral component of membrane	Cellular component	-
ZNF800	168850	zinc finger protein 800	transcription, DNA-templated	Biological process	-
SOX17	64321	SRY (sex determining region Y)-box 17	stem cell fate specification	Biological process	-
MTIF3	219402	mitochondrial translational initiation factor 3	protein binding	Molecular function	25416956
FDXACB1	91893	ferredoxin-fold anticodon binding domain containing 1	magnesium ion binding	Molecular function	-
CDC16	8881	cell division cycle 16	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	Biological process	-
PEA15	8682	phosphoprotein enriched in astrocytes 15	cytoplasm	Cellular component	-
GSTP1	2950	glutathione S-transferase pi 1	negative regulation of leukocyte proliferation	Biological process	-
PROX1	5629	prospero homeobox 1	response to nutrient levels	Biological process	-
SYT15	83849	synaptotagmin XV	calcium ion-dependent exocytosis of neurotransmitter	Biological process	-
APOH	350	apolipoprotein H (beta-2-glycoprotein I)	chylomicron	Cellular component	222615
F11	2160	coagulation factor XI	heparin binding	Molecular function	-
PIK3R1	5295	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	negative regulation of osteoclast differentiation	Biological process	-
Sep-03	55964	septin 3	cell junction	Cellular component	-
HOXD8	3234	homeobox D8	skeletal system morphogenesis	Biological process	-
PCSK4	54760	proprotein convertase subtilisin/kexin type 4	protein processing	Biological process	-
MEF2C	4208	myocyte enhancer factor 2C	regulation of synapse assembly	Biological process	-
RETNLB	84666	resistin like beta	extracellular region	Cellular component	-
PTH1R	5745	parathyroid hormone 1 receptor	phospholipase C-activating G-protein coupled receptor signaling pathway	Biological process	19608645
LCAT	3931	lecithin-cholesterol acyltransferase	phosphatidylcholine biosynthetic process	Biological process	11966470
PRSS56	646960	protease, serine, 56	serine-type endopeptidase activity	Molecular function	-
GLRA1	2741	glycine receptor, alpha 1	action potential	Biological process	-
RET	5979	ret proto-oncogene	positive regulation of neuron projection development	Biological process	17910947
MLEC	9761	malectin	carbohydrate binding	Molecular function	-
RSU1	6251	Ras suppressor protein 1	extracellular exosome	Cellular component	20458337
KIF3B	9371	kinesin family member 3B	ciliary tip	Cellular component	-
PLRG1	5356	pleiotropic regulator 1	positive regulation of G1/S transition of mitotic cell cycle	Biological process	-
PNKP	11284	polynucleotide kinase 3'-phosphatase	DNA-dependent DNA replication	Biological process	10446192
USP15	9958	ubiquitin specific peptidase 15	monoubiquitinated protein deubiquitination	Biological process	21947082
HDAC1	3065	histone deacetylase 1	RNA polymerase II transcription corepressor activity	Molecular function	15919722
GTF3C1	2975	general transcription factor IIIC, polypeptide 1, alpha 220kDa	5S class rRNA transcription from RNA polymerase III type 1 promoter	Biological process	17409385
NFATC3	4775	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	nucleoplasm	Cellular component	-
PTK6	5753	protein tyrosine kinase 6	nucleus	Cellular component	10913193
PLIN3	10226	perilipin 3	membrane	Cellular component	19946888
ARX	170302	aristaless related homeobox	transcription, DNA-templated	Biological process	-
BRAF	673	B-Raf proto-oncogene, serine/threonine kinase	negative regulation of synaptic vesicle exocytosis	Biological process	-
CD3G	917	CD3g molecule, gamma (CD3-TCR complex)	establishment or maintenance of cell polarity	Biological process	12407027
PF4	5196	platelet factor 4	immune response	Biological process	-
FGF21	26291	fibroblast growth factor 21	extracellular region	Cellular component	-
STX8	9482	syntaxin 8	SNAP receptor activity	Molecular function	-
MSH3	4437	mutS homolog 3	nucleus	Cellular component	-
HAX1	10456	HCLS1 associated protein X-1	apical plasma membrane	Cellular component	-
SRI	6717	sorcin	regulation of cell communication by electrical coupling involved in cardiac conduction	Biological process	17130302
EIF3I	8668	eukaryotic translation initiation factor 3, subunit I	translational initiation	Biological process	-
PTPN3	5774	protein tyrosine phosphatase, non-receptor type 3	cytoplasm	Cellular component	10940933
LMF1	64788	lipase maturation factor 1	regulation of cholesterol metabolic process	Biological process	-
DMRT2	10655	doublesex and mab-3 related transcription factor 2	sequence-specific DNA binding transcription factor activity	Molecular function	-
PSEN1	5663	presenilin 1	dendritic shaft	Cellular component	-
CSRNP1	64651	cysteine-serine-rich nuclear protein 1	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
VAMP1	6843	vesicle-associated membrane protein 1 (synaptobrevin 1)	cytosol	Cellular component	-
SIRT1	23411	sirtuin 1	chromatin silencing at rDNA	Biological process	-
ATP1A4	480	ATPase, Na+/K+ transporting, alpha 4 polypeptide	metal ion binding	Molecular function	-
ATF7	11016	activating transcription factor 7	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	8288576
BIRC5	332	baculoviral IAP repeat containing 5	interphase microtubule organizing center	Cellular component	9859993
CDC37L1	55664	cell division cycle 37-like 1	heat shock protein binding	Molecular function	-
MYL2	4633	myosin, light chain 2, regulatory, cardiac, slow	cytosol	Cellular component	-
TBX3	6926	T-box 3	sinoatrial node cell development	Biological process	-
SST	6750	somatostatin	response to steroid hormone	Biological process	-
CDC5L	988	cell division cycle 5-like	nucleus	Cellular component	-
GNB4	59345	guanine nucleotide binding protein (G protein), beta polypeptide 4	lysosomal membrane	Cellular component	17897319
ATP7B	540	ATPase, Cu++ transporting, beta polypeptide	Golgi membrane	Cellular component	-
IGF1R	3480	insulin-like growth factor 1 receptor	negative regulation of sequence-specific DNA binding transcription factor activity	Biological process	-
ATG7	10533	autophagy related 7	negative regulation of histone H4-K16 acetylation	Biological process	-
PHF3	23469	PHD finger protein 3	multicellular organismal development	Biological process	11856869
TCEA2	6919	transcription elongation factor A (SII), 2	DNA-templated transcription, elongation	Biological process	8566795
RAB29	8934	RAB29, member RAS oncogene family	intracellular protein transport	Biological process	-
SSTR2	6752	somatostatin receptor 2	neuropeptide signaling pathway	Biological process	-
ADIPOQ	9370	adiponectin, C1Q and collagen domain containing	positive regulation of glycogen (starch) synthase activity	Biological process	-
BUB3	9184	BUB3 mitotic checkpoint protein	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	Biological process	-
MAFIP	727764	MAFF interacting protein (pseudogene)	nucleolus	Cellular component	-
SH3BGRL	6451	SH3 domain binding glutamate-rich protein like	nucleus	Cellular component	16130169
ZNF583	147949	zinc finger protein 583	transcription, DNA-templated	Biological process	-
MAP3K2	10746	mitogen-activated protein kinase kinase kinase 2	protein kinase activity	Molecular function	15001576
P2RX2	22953	purinergic receptor P2X, ligand gated ion channel, 2	ion transmembrane transport	Biological process	-
PLA2G2D	26279	phospholipase A2, group IID	phosphatidylcholine acyl-chain remodeling	Biological process	-
RPGRIP1L	23322	RPGRIP1-like	olfactory bulb development	Biological process	-
DICER1	23405	dicer 1, ribonuclease type III	regulation of viral genome replication	Biological process	-
TSPY2	64591	testis specific protein, Y-linked 2	gonadal mesoderm development	Biological process	-
KDM2B	84678	lysine (K)-specific demethylase 2B	initiation of neural tube closure	Biological process	-
TAS2R8	50836	taste receptor, type 2, member 8	G-protein coupled receptor signaling pathway	Biological process	-
ENPP3	5169	ectonucleotide pyrophosphatase/phosphodiesterase 3	immune response	Biological process	-
RASGRP4	115727	RAS guanyl releasing protein 4	transmembrane receptor protein tyrosine kinase signaling pathway	Biological process	11880369
POMK	84197	protein-O-mannose kinase	sensory perception of pain	Biological process	-
CDH2	1000	cadherin 2, type 1, N-cadherin (neuronal)	intercalated disc	Cellular component	-
PANK1	53354	pantothenate kinase 1	pantothenate kinase activity	Molecular function	-
NKX2-5	1482	NK2 homeobox 5	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	15649947
NDE1	54820	nudE neurodevelopment protein 1	neuron migration	Biological process	-
UNC13D	201294	unc-13 homolog D (C. elegans)	late endosome	Cellular component	-
LIF	3976	leukemia inhibitory factor	spongiotrophoblast differentiation	Biological process	-
CYP27B1	1594	cytochrome P450, family 27, subfamily B, polypeptide 1	positive regulation of vitamin D receptor signaling pathway	Biological process	16549446
NF1	4763	neurofibromin 1	cell communication	Biological process	-
NPM1	4869	nucleophosmin (nucleolar phosphoprotein B23, numatrin)	spindle pole centrosome	Cellular component	16041368
B4GALNT1	2583	beta-1,4-N-acetyl-galactosaminyl transferase 1	lipid storage	Biological process	-
FCGR2B	2213	Fc fragment of IgG, low affinity IIb, receptor (CD32)	plasma membrane	Cellular component	-
MMP17	4326	matrix metallopeptidase 17 (membrane-inserted)	proteolysis	Biological process	-
HOMER1	9456	homer scaffolding protein 1	identical protein binding	Molecular function	-
THRB	7068	thyroid hormone receptor, beta	organ morphogenesis	Biological process	-
MFRP	83552	membrane frizzled-related protein	molecular_function	Molecular function	-
MSN	4478	moesin	protein kinase binding	Molecular function	19255442
SH2D1B	117157	SH2 domain containing 1B	protein binding	Molecular function	12928397
CSF1R	1436	colony stimulating factor 1 receptor	inflammatory response	Biological process	19132917
NCK1	4690	NCK adaptor protein 1	negative regulation of PERK-mediated unfolded protein response	Biological process	14676213
HAPLN4	404037	hyaluronan and proteoglycan link protein 4	cell adhesion	Biological process	-
MYO1F	4542	myosin IF	biological_process	Biological process	-
HIST2H3D	653604	histone cluster 2, H3d	extracellular exosome	Cellular component	19199708
LGR4	55366	leucine-rich repeat containing G protein-coupled receptor 4	integral component of plasma membrane	Cellular component	22815884
B2M	567	beta-2-microglobulin	glycoprotein binding	Molecular function	9465039
TLR2	7097	toll-like receptor 2	positive regulation of Wnt signaling pathway	Biological process	16601243
OR4K5	79317	olfactory receptor, family 4, subfamily K, member 5	plasma membrane	Cellular component	-
AUTS2	26053	autism susceptibility candidate 2	molecular_function	Molecular function	-
VDAC2	7417	voltage-dependent anion channel 2	transmembrane transport	Biological process	-
ARID3B	10620	AT rich interactive domain 3B (BRIGHT-like)	nucleus	Cellular component	10446990
LAMA3	3909	laminin, alpha 3	hemidesmosome assembly	Biological process	-
NRP1	8829	neuropilin 1	vestibulocochlear nerve structural organization	Biological process	-
RPL22L1	200916	ribosomal protein L22-like 1	translation	Biological process	-
TAB3	257397	TGF-beta activated kinase 1/MAP3K7 binding protein 3	nucleoplasm	Cellular component	-
SCO1	6341	SCO1 cytochrome c oxidase assembly protein	copper ion binding	Molecular function	-
VCX	26609	variable charge, X-linked	spermatogenesis	Biological process	10607842
KIAA0753	9851	KIAA0753	protein binding	Molecular function	25416956
PTPN23	25930	protein tyrosine phosphatase, non-receptor type 23	extracellular exosome	Cellular component	19056867
PMPCA	23203	peptidase (mitochondrial processing) alpha	mitochondrial matrix	Cellular component	-
RPL37A	6168	ribosomal protein L37a	nucleus	Cellular component	21630459
WNT4	54361	wingless-type MMTV integration site family, member 4	mammary gland epithelium development	Biological process	8168088
IGHA1	3493	immunoglobulin heavy constant alpha 1	positive regulation of respiratory burst	Biological process	24145934
ABL1	25	ABL proto-oncogene 1, non-receptor tyrosine kinase	cerebellum morphogenesis	Biological process	-
DSP	1832	desmoplakin	protein binding	Molecular function	10852826
IFNG	3458	interferon, gamma	response to drug	Biological process	-
SMARCC2	6601	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	16217013
EIF3M	10480	eukaryotic translation initiation factor 3, subunit M	translation initiation factor activity	Molecular function	17322308
PHYHIPL	84457	phytanoyl-CoA 2-hydroxylase interacting protein-like	mitochondrion	Cellular component	-
NGDN	25983	neuroguidin, EIF4E binding protein	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Biological process	-
SMARCE1	6605	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	protein N-terminus binding	Molecular function	12917342
SSTR1	6751	somatostatin receptor 1	synaptic transmission	Biological process	-
PTCH1	5727	patched 1	negative regulation of transcription from RNA polymerase II promoter	Biological process	16229683
PRF1	5551	perforin 1 (pore forming protein)	integral component of membrane	Cellular component	20889983
CAPN3	825	calpain 3, (p94)	negative regulation of apoptotic process	Biological process	18073330
SNAP25	6616	synaptosomal-associated protein, 25kDa	SNARE complex	Cellular component	15217342
TUT1	64852	terminal uridylyl transferase 1, U6 snRNA-specific	mRNA cleavage and polyadenylation specificity factor complex	Cellular component	18305108
EDNRB	1910	endothelin receptor type B	plasma membrane	Cellular component	-
CA2	760	carbonic anhydrase II	carbonate dehydratase activity	Molecular function	7758465
HIPK2	28996	homeodomain interacting protein kinase 2	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
ERCC1	2067	excision repair cross-complementation group 1	cytoplasm	Cellular component	-
FKBP10	60681	FK506 binding protein 10, 65 kDa	calcium ion binding	Molecular function	-
IRAK2	3656	interleukin-1 receptor-associated kinase 2	protein serine/threonine kinase activity	Molecular function	-
VEGFA	7422	vascular endothelial growth factor A	positive regulation of axon extension involved in axon guidance	Biological process	-
ARHGAP22	58504	Rho GTPase activating protein 22	transcription, DNA-templated	Biological process	-
INSIG2	51141	insulin induced gene 2	negative regulation of steroid biosynthetic process	Biological process	-
AK4	205	adenylate kinase 4	GTP metabolic process	Biological process	19766732
SERPINA6	866	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6	extracellular exosome	Cellular component	23376485
NPPC	4880	natriuretic peptide C	regulation of cAMP metabolic process	Biological process	20947764
KIT	3815	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	cytokine-mediated signaling pathway	Biological process	21640708
FYN	2534	FYN proto-oncogene, Src family tyrosine kinase	actin filament	Cellular component	-
CD302	9936	CD302 molecule	microvillus	Cellular component	-
ST3GAL6	10402	ST3 beta-galactoside alpha-2,3-sialyltransferase 6	cellular protein modification process	Biological process	10206952
IRF7	3665	interferon regulatory factor 7	positive regulation of interferon-alpha production	Biological process	16979567
SMAD1	4086	SMAD family member 1	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	12270938
CDCA2	157313	cell division cycle associated 2	mitotic nuclear division	Biological process	-
SSR2	6746	signal sequence receptor, beta (translocon-associated protein beta)	endoplasmic reticulum membrane	Cellular component	-
HBB	3043	hemoglobin, beta	oxygen transporter activity	Molecular function	11747442
SETMAR	6419	SET domain and mariner transposase fusion gene	double-strand break repair via nonhomologous end joining	Biological process	18263876
KCNE4	23704	potassium channel, voltage gated subfamily E regulatory beta subunit 4	potassium ion transmembrane transport	Biological process	-
WIPF1	7456	WAS/WASL interacting protein family, member 1	actin cytoskeleton	Cellular component	9405671
PKD1L3	342372	polycystic kidney disease 1-like 3	cation transmembrane transporter activity	Molecular function	-
LDHA	3939	lactate dehydrogenase A	membrane	Cellular component	19946888
HSPA1B	3304	heat shock 70kDa protein 1B	double-stranded RNA binding	Molecular function	21266579
TBCCD1	55171	TBCC domain containing 1	maintenance of centrosome location	Biological process	20168327
UVRAG	7405	UV radiation resistance associated	cytoplasm	Cellular component	9169138
TIPIN	54962	TIMELESS interacting protein	response to UV	Biological process	-
SPG20	23111	spastic paraplegia 20 (Troyer syndrome)	neuromuscular process	Biological process	-
MCOLN2	255231	mucolipin 2	ion transmembrane transport	Biological process	-
AQP4	361	aquaporin 4	cellular response to estradiol stimulus	Biological process	-
SFRP1	6422	secreted frizzled-related protein 1	cellular response to X-ray	Biological process	-
MT2A	4502	metallothionein 2A	cellular response to drug	Biological process	19536566
DBH	1621	dopamine beta-hydroxylase (dopamine beta-monooxygenase)	cytoplasm	Cellular component	3443096
PDIA2	64714	protein disulfide isomerase family A, member 2	protein binding	Molecular function	17474147
CTSC	1075	cathepsin C	proteolysis involved in cellular protein catabolic process	Biological process	-
KIAA0368	23392	KIAA0368	proteasome complex	Cellular component	15496406
NR2F1	7025	nuclear receptor subfamily 2, group F, member 1	ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity	Molecular function	-
RGS9	8787	regulator of G-protein signaling 9	phototransduction, visible light	Biological process	-
LMTK3	114783	lemur tyrosine kinase 3	integral component of membrane	Cellular component	-
COLGALT1	79709	collagen beta(1-O)galactosyltransferase 1	metabolic process	Biological process	-
PARK7	11315	parkinson protein 7	ubiquitin-specific protease binding	Molecular function	21097510
SLC18A2	6571	solute carrier family 18 (vesicular monoamine transporter), member 2	clathrin-sculpted monoamine transport vesicle membrane	Cellular component	-
TRAIP	10293	TRAF interacting protein	receptor signaling protein activity	Molecular function	-
TNFAIP3	7128	tumor necrosis factor, alpha-induced protein 3	lysosome	Cellular component	-
FOXA1	3169	forkhead box A1	hormone metabolic process	Biological process	-
HGS	9146	hepatocyte growth factor-regulated tyrosine kinase substrate	protein domain specific binding	Molecular function	11984006
P3H1	64175	prolyl 3-hydroxylase 1	chaperone-mediated protein folding	Biological process	15044469
GC	2638	group-specific component (vitamin D binding protein)	vitamin D binding	Molecular function	1696927
CD4	920	CD4 molecule	external side of plasma membrane	Cellular component	17213291
TPT1P8	59347	tumor protein, translationally-controlled 1 pseudogene 8	apoptotic process	Biological process	-
RB1	5925	retinoblastoma 1	protein binding	Molecular function	10613832
CPAMD8	27151	C3 and PZP-like, alpha-2-macroglobulin domain containing 8	extracellular space	Cellular component	-
DNM2	1785	dynamin 2	growth cone	Cellular component	-
UBB	7314	ubiquitin B	regulation of necrotic cell death	Biological process	-
KCNS3	3790	potassium voltage-gated channel, modifier subfamily S, member 3	small molecule metabolic process	Biological process	-
KIT	3815	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	male gonad development	Biological process	17848411
RCCD1	91433	RCC1 domain containing 1	plasma membrane	Cellular component	-
P2RY13	53829	purinergic receptor P2Y, G-protein coupled, 13	G-protein coupled purinergic nucleotide receptor signaling pathway	Biological process	-
SF3B2	10992	splicing factor 3b, subunit 2, 145kDa	viral process	Biological process	-
SLC47A1	55244	solute carrier family 47 (multidrug and toxin extrusion), member 1	integral component of membrane	Cellular component	-
SIRT1	23411	sirtuin 1	negative regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	17680780
LITAF	9516	lipopolysaccharide-induced TNF factor	Golgi apparatus	Cellular component	16118794
BRINP2	57795	bone morphogenetic protein/retinoic acid inducible neural-specific 2	extracellular region	Cellular component	-
TXNIP	10628	thioredoxin interacting protein	response to glucose	Biological process	-
DLG1	1739	discs, large homolog 1 (Drosophila)	phosphatase binding	Molecular function	10646847
HADHA	3030	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit	acetyl-CoA C-acetyltransferase activity	Molecular function	8135828
COX7C	1350	cytochrome c oxidase subunit VIIc	cellular metabolic process	Biological process	-
PPP1R3B	79660	protein phosphatase 1, regulatory subunit 3B	enzyme binding	Molecular function	-
TOR1A	1861	torsin family 1, member A (torsin A)	protein binding	Molecular function	15147511
CHORDC1	26973	cysteine and histidine-rich domain (CHORD) containing 1	zinc ion binding	Molecular function	-
NOL11	25926	nucleolar protein 11	nucleolus	Cellular component	-
FOXP1	27086	forkhead box P1	negative regulation of transcription, DNA-templated	Biological process	20950788
MAGEL2	54551	melanoma antigen family L2	nucleus	Cellular component	-
STX19	415117	syntaxin 19	SNARE binding	Molecular function	-
CHRNA2	1135	cholinergic receptor, nicotinic, alpha 2 (neuronal)	protein heterooligomerization	Biological process	-
SDHD	6392	succinate dehydrogenase complex, subunit D, integral membrane protein	electron carrier activity	Molecular function	9533030
ADAM9	8754	ADAM metallopeptidase domain 9	metalloendopeptidase activity	Molecular function	22480688
FCGR2C	9103	Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)	signal transduction	Biological process	2531080
P2RY1	5028	purinergic receptor P2Y, G-protein coupled, 1	sensory perception of pain	Biological process	-
SLC4A1	6521	solute carrier family 4 (anion exchanger), member 1 (Diego blood group)	anion transmembrane transporter activity	Molecular function	4027230
NRTN	4902	neurturin	axon	Cellular component	-
TALDO1	6888	transaldolase 1	cytoplasm	Cellular component	16130169
SLC4A9	83697	solute carrier family 4, sodium bicarbonate cotransporter, member 9	apical part of cell	Cellular component	-
EIF3F	8665	eukaryotic translation initiation factor 3, subunit F	eukaryotic 48S preinitiation complex	Cellular component	-
BARHL1	56751	BarH-like homeobox 1	nucleus	Cellular component	-
SLC32A1	140679	solute carrier family 32 (GABA vesicular transporter), member 1	dendrite terminus	Cellular component	-
KIDINS220	57498	kinase D-interacting substrate, 220kDa	PDZ domain binding	Molecular function	-
WDR27	253769	WD repeat domain 27	nucleoplasm	Cellular component	-
BMP8B	656	bone morphogenetic protein 8b	transforming growth factor beta receptor binding	Molecular function	-
LYN	4067	LYN proto-oncogene, Src family tyrosine kinase	regulation of platelet aggregation	Biological process	-
ATP1A3	478	ATPase, Na+/K+ transporting, alpha 3 polypeptide	integral component of membrane	Cellular component	15260953
NUBP2	10101	nucleotide binding protein 2	spindle pole centrosome	Cellular component	-
CYP26A1	1592	cytochrome P450, family 26, subfamily A, polypeptide 1	vitamin metabolic process	Biological process	-
MTRR	4552	5-methyltetrahydrofolate-homocysteine methyltransferase reductase	NADPH binding	Molecular function	11466310
ZFHX2	85446	zinc finger homeobox 2	regulation of transcription, DNA-templated	Biological process	-
PROL1	58503	proline rich, lacrimal 1	regulation of sensory perception of pain	Biological process	17101991
WDR5	11091	WD repeat domain 5	histone acetyltransferase activity (H4-K8 specific)	Molecular function	20018852
ZNF497	162968	zinc finger protein 497	regulation of transcription, DNA-templated	Biological process	-
SALL1	6299	spalt-like transcription factor 1	hindlimb morphogenesis	Biological process	-
FAM101B	359845	family with sequence similarity 101, member B	epithelial to mesenchymal transition	Biological process	-
OAS2	4939	2'-5'-oligoadenylate synthetase 2, 69/71kDa	2'-5'-oligoadenylate synthetase activity	Molecular function	10464285
CAMK2B	816	calcium/calmodulin-dependent protein kinase II beta	cytosol	Cellular component	-
MTRR	4552	5-methyltetrahydrofolate-homocysteine methyltransferase reductase	cytoplasm	Cellular component	-
PRAMEF25	441873	PRAME family member 25	negative regulation of transcription, DNA-templated	Biological process	-
SCN2A	6326	sodium channel, voltage gated, type II alpha subunit	voltage-gated sodium channel activity	Molecular function	-
MYOF	26509	myoferlin	blood circulation	Biological process	10607832
CSF1R	1436	colony stimulating factor 1 receptor	regulation of bone resorption	Biological process	-
WNT1	7471	wingless-type MMTV integration site family, member 1	plasma membrane	Cellular component	-
SP7	121340	Sp7 transcription factor	nucleus	Cellular component	18471237
TLR8	51311	toll-like receptor 8	regulation of cytokine secretion	Biological process	-
MTMR3	8897	myotubularin related protein 3	phosphatidylinositol dephosphorylation	Biological process	10900271
CRTC2	200186	CREB regulated transcription coactivator 2	gluconeogenesis	Biological process	-
CEP57L1	285753	centrosomal protein 57kDa-like 1	protein binding	Molecular function	25416956
DNAJB2	3300	DnaJ (Hsp40) homolog, subfamily B, member 2	Hsp70 protein binding	Molecular function	15936278
BCL2L11	10018	BCL2-like 11 (apoptosis facilitator)	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	Biological process	22013210
ST6GALNAC2	10610	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2	sialylation	Biological process	-
CD47	961	CD47 molecule	integral component of plasma membrane	Cellular component	-
NLGN3	54413	neuroligin 3	synapse	Cellular component	-
HIST1H3I	8354	histone cluster 1, H3i	protein binding	Molecular function	10949293
GPNMB	10457	glycoprotein (transmembrane) nmb	cell adhesion	Biological process	-
UGDH	7358	UDP-glucose 6-dehydrogenase	extracellular exosome	Cellular component	23533145
SFRP1	6422	secreted frizzled-related protein 1	positive regulation of epithelial cell proliferation	Biological process	16288033
SDS	10993	serine dehydratase	pyruvate biosynthetic process	Biological process	15689518
NRG1	3084	neuregulin 1	positive regulation of Ras protein signal transduction	Biological process	-
MRPL44	65080	mitochondrial ribosomal protein L44	mitochondrial translational termination	Biological process	-
GRB7	2886	growth factor receptor-bound protein 7	cytosol	Cellular component	-
CCT3	7203	chaperonin containing TCP1, subunit 3 (gamma)	unfolded protein binding	Molecular function	-
TCEAL8	90843	transcription elongation factor A (SII)-like 8	regulation of transcription, DNA-templated	Biological process	-
DDR2	4921	discoidin domain receptor tyrosine kinase 2	protein tyrosine kinase collagen receptor activity	Molecular function	9659899
GRSF1	2926	G-rich RNA sequence binding factor 1	cytoplasm	Cellular component	8036161
DNAJA3	9093	DnaJ (Hsp40) homolog, subfamily A, member 3	interferon-gamma receptor binding	Molecular function	11679576
FOXP3	50943	forkhead box P3	sequence-specific DNA binding transcription factor activity	Molecular function	11138001
ADAMTS12	81792	ADAM metallopeptidase with thrombospondin type 1 motif, 12	proteinaceous extracellular matrix	Cellular component	-
SOX11	6664	SRY (sex determining region Y)-box 11	embryonic digestive tract morphogenesis	Biological process	-
ECM1	1893	extracellular matrix protein 1	regulation of transcription from RNA polymerase II promoter	Biological process	-
ELSPBP1	64100	epididymal sperm binding protein 1	extracellular region	Cellular component	-
CD70	970	CD70 molecule	plasma membrane	Cellular component	11920585
POLR3D	661	polymerase (RNA) III (DNA directed) polypeptide D, 44kDa	innate immune response	Biological process	-
EPM2A	7957	epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)	small molecule metabolic process	Biological process	-
HFE	3077	hemochromatosis	BMP signaling pathway	Biological process	24904118
ANP32B	10541	acidic (leucine-rich) nuclear phosphoprotein 32 family, member B	vasculature development	Biological process	-
SLC2A3	6515	solute carrier family 2 (facilitated glucose transporter), member 3	plasma membrane	Cellular component	-
CCL2	6347	chemokine (C-C motif) ligand 2	G-protein coupled receptor signaling pathway	Biological process	10542238
OR5K3	403277	olfactory receptor, family 5, subfamily K, member 3	sensory perception of smell	Biological process	-
APOE	348	apolipoprotein E	response to dietary excess	Biological process	-
PDE3B	5140	phosphodiesterase 3B, cGMP-inhibited	blood coagulation	Biological process	-
RAB40A	142684	RAB40A, member RAS oncogene family	protein ubiquitination	Biological process	-
PCDHA8	56140	protocadherin alpha 8	homophilic cell adhesion via plasma membrane adhesion molecules	Biological process	-
GAA	2548	glucosidase, alpha; acid	muscle cell cellular homeostasis	Biological process	-
SLC22A1	6580	solute carrier family 22 (organic cation transporter), member 1	membrane	Cellular component	9187257
ADCY10	55811	adenylate cyclase 10 (soluble)	plasma membrane	Cellular component	-
TGFB1	7040	transforming growth factor, beta 1	negative regulation of neuroblast proliferation	Biological process	-
MYO9B	4650	myosin IXB	ruffle	Cellular component	-
AQP1	358	aquaporin 1 (Colton blood group)	plasma membrane	Cellular component	-
HTR5A	3361	5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled	perikaryon	Cellular component	-
ZSCAN1	284312	zinc finger and SCAN domain containing 1	transcription from RNA polymerase II promoter	Biological process	-
S100A4	6275	S100 calcium binding protein A4	positive regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	15033494
PROX1	5629	prospero homeobox 1	positive regulation of sarcomere organization	Biological process	-
TNP1	7141	transition protein 1 (during histone to protamine replacement)	nucleosome disassembly	Biological process	10781074
MIF	4282	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	positive chemotaxis	Biological process	19602265
LYN	4067	LYN proto-oncogene, Src family tyrosine kinase	positive regulation of cellular component movement	Biological process	16467205
SERPINE1	5054	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	transcription, DNA-templated	Biological process	-
MYOG	4656	myogenin (myogenic factor 4)	protein binding	Molecular function	25416956
KRT78	196374	keratin 78, type II	extracellular space	Cellular component	22664934
GABRA2	2555	gamma-aminobutyric acid (GABA) A receptor, alpha 2	neurotransmitter transport	Biological process	8391122
SLC26A6	65010	solute carrier family 26 (anion exchanger), member 6	regulation of intracellular pH	Biological process	20501439
ABCG2	9429	ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)	transmembrane transport	Biological process	-
PPARG	5468	peroxisome proliferator-activated receptor gamma	negative regulation of cell growth	Biological process	-
ENTPD5	957	ectonucleoside triphosphate diphosphohydrolase 5	guanosine-diphosphatase activity	Molecular function	-
B2M	567	beta-2-microglobulin	extracellular space	Cellular component	16502470
AP1M1	8907	adaptor-related protein complex 1, mu 1 subunit	clathrin adaptor complex	Cellular component	-
FTH1	2495	ferritin, heavy polypeptide 1	extracellular exosome	Cellular component	19056867
EPHA2	1969	EPH receptor A2	vasculogenesis	Biological process	-
CCDC40	55036	coiled-coil domain containing 40	regulation of cilium beat frequency	Biological process	21131974
TAOK2	9344	TAO kinase 2	mitogen-activated protein kinase kinase binding	Molecular function	11279118
SNX3	8724	sorting nexin 3	positive regulation of neuron projection development	Biological process	-
MAP3K1	4214	mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase	wound healing	Biological process	-
RAC1	5879	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	platelet activation	Biological process	-
OCLN	100506658	occludin	cytoplasmic vesicle	Cellular component	20164257
MYL6	4637	myosin, light chain 6, alkali, smooth muscle and non-muscle	muscle contraction	Biological process	2304459
HMOX1	3162	heme oxygenase 1	cell death	Biological process	-
EMX1	2016	empty spiracles homeobox 1	cerebral cortex regionalization	Biological process	-
EHD3	30845	EH-domain containing 3	recycling endosome membrane	Cellular component	17233914
PLEKHA8	84725	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8	ceramide binding	Molecular function	17687330
MEI1	150365	meiosis inhibitor 1	male meiosis I	Biological process	-
PNPT1	87178	polyribonucleotide nucleotidyltransferase 1	regulation of cellular senescence	Biological process	16055741
KLHDC3	116138	kelch domain containing 3	cytosol	Cellular component	-
KLRF1	51348	killer cell lectin-like receptor subfamily F, member 1	MHC class I receptor activity	Molecular function	10671213
MNT	4335	MAX network transcriptional repressor	transcription coactivator activity	Molecular function	9598315
PIAS4	51588	protein inhibitor of activated STAT, 4	PML body	Cellular component	-
FGF23	8074	fibroblast growth factor 23	innate immune response	Biological process	-
PTCD2	79810	pentatricopeptide repeat domain 2	mitochondrion	Cellular component	18729827
DYRK1B	9149	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B	ATP binding	Molecular function	-
SMAD7	4092	SMAD family member 7	response to laminar fluid shear stress	Biological process	9256479
PLAUR	5329	plasminogen activator, urokinase receptor	negative regulation of intrinsic apoptotic signaling pathway	Biological process	22984561
PRKCQ	5588	protein kinase C, theta	negative regulation of T cell apoptotic process	Biological process	11342610
SPINK5	11005	serine peptidase inhibitor, Kazal type 5	cell cortex	Cellular component	12915442
SLC6A2	6530	solute carrier family 6 (neurotransmitter transporter), member 2	synaptic transmission	Biological process	2008212
ACTA1	58	actin, alpha 1, skeletal muscle	filopodium	Cellular component	-
AGBL4	84871	ATP/GTP binding protein-like 4	proteolysis	Biological process	-
MICAL2	9645	microtubule associated monooxygenase, calponin and LIM domain containing 2	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	Molecular function	-
SRSF10	10772	serine/arginine-rich splicing factor 10	nucleoplasm	Cellular component	11684676
ARL2BP	23568	ADP-ribosylation factor-like 2 binding protein	signal transduction	Biological process	10488091
C6	729	complement component 6	complement activation, classical pathway	Biological process	-
NCSTN	23385	nicastrin	plasma membrane	Cellular component	-
INPP5K	51763	inositol polyphosphate-5-phosphatase K	negative regulation of protein kinase activity	Biological process	12556481
EXO5	64789	exonuclease 5	DNA binding	Molecular function	-
ADCYAP1	116	adenylate cyclase activating polypeptide 1 (pituitary)	ovarian follicle development	Biological process	-
STEAP2	261729	STEAP family member 2, metalloreductase	early endosome	Cellular component	12095985
DPM2	8818	dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit	cellular protein metabolic process	Biological process	-
DLG1	1739	discs, large homolog 1 (Drosophila)	phosphoprotein phosphatase activity	Molecular function	15302935
KLF7	8609	Kruppel-like factor 7 (ubiquitous)	positive regulation of transcription, DNA-templated	Biological process	-
PEX13	5194	peroxisomal biogenesis factor 13	protein binding	Molecular function	10704444
B3GNT8	374907	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8	poly-N-acetyllactosamine biosynthetic process	Biological process	15620693
SLC6A17	388662	solute carrier family 6 (neutral amino acid transporter), member 17	leucine transport	Biological process	-
CNP	1267	2',3'-cyclic nucleotide 3' phosphodiesterase	microvillus	Cellular component	-
RNF11	26994	ring finger protein 11	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	14755250
ACTB	60	actin, beta	cytosol	Cellular component	-
OR52W1	120787	olfactory receptor, family 52, subfamily W, member 1	G-protein coupled receptor activity	Molecular function	-
DCT	1638	dopachrome tautomerase	cytosol	Cellular component	-
CA8	767	carbonic anhydrase VIII	carbonate dehydratase activity	Molecular function	-
NOTCH1	4851	notch 1	endoderm development	Biological process	-
IL4R	3566	interleukin 4 receptor	extracellular space	Cellular component	-
STIL	6491	SCL/TAL1 interrupting locus	notochord development	Biological process	-
PEAK1	79834	pseudopodium-enriched atypical kinase 1	actin cytoskeleton	Cellular component	20534451
TTYH1	57348	tweety family member 1	transmembrane transport	Biological process	-
HERC5	51191	HECT and RLD domain containing E3 ubiquitin protein ligase 5	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	-
AZI2	64343	5-azacytidine induced 2	I-kappaB kinase/NF-kappaB signaling	Biological process	-
ITPKB	3707	inositol-trisphosphate 3-kinase B	MAPK cascade	Biological process	-
BMP8B	656	bone morphogenetic protein 8b	BMP signaling pathway	Biological process	-
PML	5371	promyelocytic leukemia	positive regulation of apoptotic process involved in mammary gland involution	Biological process	11080164
PRDM14	63978	PR domain containing 14	histone H3-R26 methylation	Biological process	-
THOC7	80145	THO complex 7	THO complex	Cellular component	15998806
OSBP	5007	oxysterol binding protein	nucleolus	Cellular component	-
SHMT1	6470	serine hydroxymethyltransferase 1 (soluble)	water-soluble vitamin metabolic process	Biological process	-
PRKCQ	5588	protein kinase C, theta	positive regulation of interleukin-17 production	Biological process	-
TPO	7173	thyroid peroxidase	plasma membrane	Cellular component	-
ADGRF1	266977	adhesion G protein-coupled receptor F1	integral component of membrane	Cellular component	-
PTCH1	5727	patched 1	midbody	Cellular component	-
CRP	1401	C-reactive protein, pentraxin-related	protein polymerization	Biological process	-
TAOK1	57551	TAO kinase 1	mitotic cell cycle	Biological process	-
RABEP1	9135	rabaptin, RAB GTPase binding effector protein 1	growth factor activity	Molecular function	-
SIRT2	22933	sirtuin 2	NAD-dependent histone deacetylase activity	Molecular function	24177535
TAPBP	6892	TAP binding protein (tapasin)	TAP complex	Cellular component	17947644
POLN	353497	polymerase (DNA directed) nu	protein binding	Molecular function	19995904
CDC42	998	cell division cycle 42	filopodium	Cellular component	11035016
NFYC	4802	nuclear transcription factor Y, gamma	transcription coactivator activity	Molecular function	10446203
TAL1	6886	T-cell acute lymphocytic leukemia 1	Lsd1/2 complex	Cellular component	19497860
CD74	972	CD74 molecule, major histocompatibility complex, class II invariant chain	positive regulation of T cell differentiation	Biological process	-
CAMK2D	817	calcium/calmodulin-dependent protein kinase II delta	regulation of heart contraction	Biological process	17157285
SDC3	9672	syndecan 3	glycosaminoglycan catabolic process	Biological process	-
GRIN1	2902	glutamate receptor, ionotropic, N-methyl D-aspartate 1	response to calcium ion	Biological process	-
TEX19	400629	testis expressed 19	meiotic cell cycle	Biological process	-
NASP	4678	nuclear autoantigenic sperm protein (histone-binding)	nucleosome assembly	Biological process	25615412
DFNA5	1687	deafness, autosomal dominant 5	apoptotic process	Biological process	-
NOTCH2	4853	notch 2	receptor activity	Molecular function	9244302
CD226	10666	CD226 molecule	protein binding	Molecular function	21982860
RNF148	378925	ring finger protein 148	integral component of membrane	Cellular component	-
BBS1	582	Bardet-Biedl syndrome 1	nonmotile primary cilium assembly	Biological process	17980398
TRPM5	29850	transient receptor potential cation channel, subfamily M, member 5	ion transmembrane transport	Biological process	-
DYRK1B	9149	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B	protein serine/threonine kinase activity	Molecular function	-
C3orf18	51161	chromosome 3 open reading frame 18	integral component of membrane	Cellular component	-
RELL2	285613	RELT-like 2	plasma membrane	Cellular component	-
IL21R	50615	interleukin 21 receptor	interleukin-21 receptor activity	Molecular function	11081504
RPS6KL1	83694	ribosomal protein S6 kinase-like 1	protein serine/threonine kinase activity	Molecular function	-
PYGL	5836	phosphorylase, glycogen, liver	glycogen metabolic process	Biological process	10980448
S100A6	6277	S100 calcium binding protein A6	S100 protein binding	Molecular function	10913138
SH2D1B	117157	SH2 domain containing 1B	positive regulation of natural killer cell mediated immunity	Biological process	-
C11orf49	79096	chromosome 11 open reading frame 49	protein binding	Molecular function	25416956
CA5BP1	340591	carbonic anhydrase VB pseudogene 1	zinc ion binding	Molecular function	-
ASCL1	429	achaete-scute family bHLH transcription factor 1	subpallium neuron fate commitment	Biological process	-
SEC14L5	9717	SEC14-like 5 (S. cerevisiae)	transporter activity	Molecular function	-
NDC80	10403	NDC80 kinetochore complex component	cytosol	Cellular component	-
CCK	885	cholecystokinin	axon hillock	Cellular component	-
ABCA10	10349	ATP-binding cassette, sub-family A (ABC1), member 10	transmembrane transport	Biological process	-
CD74	972	CD74 molecule, major histocompatibility complex, class II invariant chain	cell surface	Cellular component	17045821
PRKACB	5567	protein kinase, cAMP-dependent, catalytic, beta	water transport	Biological process	-
BRK1	55845	BRICK1, SCAR/WAVE actin-nucleating complex subunit	positive regulation of Arp2/3 complex-mediated actin nucleation	Biological process	21107423
IRS1	3667	insulin receptor substrate 1	response to insulin	Biological process	16516141
SMPD3	55512	sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)	sphingolipid metabolic process	Biological process	-
ALPI	248	alkaline phosphatase, intestinal	integral component of membrane	Cellular component	-
SRGN	5552	serglycin	maintenance of protease location in mast cell secretory granule	Biological process	-
TPCN2	219931	two pore segment channel 2	plasma membrane	Cellular component	-
CIPC	85457	CLOCK-interacting pacemaker	rhythmic process	Biological process	-
PKD1	5310	polycystic kidney disease 1 (autosomal dominant)	integral component of membrane	Cellular component	10097141
SOX9	6662	SRY (sex determining region Y)-box 9	positive regulation of kidney development	Biological process	-
KDM4C	23081	lysine (K)-specific demethylase 4C	positive regulation of cell proliferation	Biological process	17277772
ZNF732	654254	zinc finger protein 732	nucleus	Cellular component	-
RAB7A	7879	RAB7A, member RAS oncogene family	intracellular membrane-bounded organelle	Cellular component	-
RABGGTA	5875	Rab geranylgeranyltransferase, alpha subunit	Rab GTPase binding	Molecular function	-
EXT1	2131	exostosin glycosyltransferase 1	mesoderm development	Biological process	-
MDM2	4193	MDM2 proto-oncogene, E3 ubiquitin protein ligase	ubiquitin-protein transferase activity	Molecular function	20173098
CHN2	1124	chimerin 2	protein binding	Molecular function	16628218
SP8	221833	Sp8 transcription factor	embryonic limb morphogenesis	Biological process	-
RNF13	11342	ring finger protein 13	ubiquitin-protein transferase activity	Molecular function	-
KRT4	3851	keratin 4, type II	keratin filament	Cellular component	21371075
BRDT	676	bromodomain, testis-specific	male meiosis I	Biological process	-
IL6	3569	interleukin 6	positive regulation of epithelial cell proliferation	Biological process	-
SLC9A3R1	9368	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1	ruffle	Cellular component	-
KLF17	128209	Kruppel-like factor 17	protein binding	Molecular function	25416956
IL4	3565	interleukin 4	T-helper 2 cell differentiation	Biological process	-
UBR2	23304	ubiquitin protein ligase E3 component n-recognin 2	spermatogenesis	Biological process	-
SPDL1	54908	spindle apparatus coiled-coil protein 1	protein binding	Molecular function	19468067
BIN1	274	bridging integrator 1	nucleus	Cellular component	-
HIST1H4K	8362	histone cluster 1, H4k	protein complex	Cellular component	14718166
RABL3	285282	RAB, member of RAS oncogene family-like 3	intracellular	Cellular component	-
PSENEN	55851	presenilin enhancer gamma secretase subunit	Notch signaling pathway	Biological process	-
FLNA	2316	filamin A, alpha	mitotic spindle assembly	Biological process	18548008
HBB	3043	hemoglobin, beta	renal absorption	Biological process	18465053
RANBP3	8498	RAN binding protein 3	Ran GTPase binding	Molecular function	9637251
RAB38	23682	RAB38, member RAS oncogene family	cytosol	Cellular component	-
CLEC4M	10332	C-type lectin domain family 4, member M	endocytosis	Biological process	-
ADA	100	adenosine deaminase	negative regulation of mature B cell apoptotic process	Biological process	-
HIST2H4B	554313	histone cluster 2, H4b	protein heterotetramerization	Biological process	20498094
EGLN2	112398	egl-9 family hypoxia-inducible factor 2	response to hypoxia	Biological process	11595184
DPEP1	1800	dipeptidase 1 (renal)	modified amino acid binding	Molecular function	20031578
QRFP	347148	pyroglutamylated RFamide peptide	orexigenic neuropeptide QRFP receptor binding	Molecular function	-
OR2AJ1	127608	olfactory receptor, family 2, subfamily AJ, member 1	G-protein coupled receptor activity	Molecular function	-
TOMM5	401505	translocase of outer mitochondrial membrane 5 homolog (yeast)	protein transporter activity	Molecular function	18331822
TERF1	7013	telomeric repeat binding factor (NIMA-interacting) 1	nuclear telomere cap complex	Cellular component	7502076
MAPK14	1432	mitogen-activated protein kinase 14	angiogenesis	Biological process	-
OR10J6P	401973	olfactory receptor, family 10, subfamily J, member 6 pseudogene	G-protein coupled receptor signaling pathway	Biological process	-
KIR2DS2	100132285	killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2	regulation of immune response	Biological process	-
HPRT1	3251	hypoxanthine phosphoribosyltransferase 1	cytolysis	Biological process	-
USPL1	10208	ubiquitin specific peptidase like 1	protein binding	Molecular function	21988832
C9orf114	51490	chromosome 9 open reading frame 114	cell division	Biological process	-
ZNF33B	7582	zinc finger protein 33B	protein binding	Molecular function	25416956
CSRNP3	80034	cysteine-serine-rich nuclear protein 3	sequence-specific DNA binding	Molecular function	-
NUP188	23511	nucleoporin 188kDa	carbohydrate metabolic process	Biological process	-
C11orf31	280636	chromosome 11 open reading frame 31	poly(A) RNA binding	Molecular function	22681889
KIF3B	9371	kinesin family member 3B	organelle organization	Biological process	-
CDK20	23552	cyclin-dependent kinase 20	cyclin-dependent protein serine/threonine kinase activity	Molecular function	-
EIF3K	27335	eukaryotic translation initiation factor 3, subunit K	translation	Biological process	-
IRF7	3665	interferon regulatory factor 7	cytosol	Cellular component	-
SYT6	148281	synaptotagmin VI	protein heterodimerization activity	Molecular function	-
MAPK9	5601	mitogen-activated protein kinase 9	Fc-epsilon receptor signaling pathway	Biological process	-
KRT82	3888	keratin 82, type II	biological_process	Biological process	-
ARAP1	116985	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1	regulation of cellular component movement	Biological process	11804590
ENPP1	5167	ectonucleotide pyrophosphatase/phosphodiesterase 1	integral component of membrane	Cellular component	-
GRIK2	2898	glutamate receptor, ionotropic, kainate 2	postsynaptic membrane	Cellular component	-
RPL7A	6130	ribosomal protein L7a	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Biological process	-
CRHR2	1395	corticotropin releasing hormone receptor 2	positive regulation of cAMP-mediated signaling	Biological process	-
CXCL14	9547	chemokine (C-X-C motif) ligand 14	cell-cell signaling	Biological process	10049774
DNAJA1	3301	DnaJ (Hsp40) homolog, subfamily A, member 1	protein binding	Molecular function	22085931
TSPO	706	translocator protein (18kDa)	cell proliferation	Biological process	16822554
IFNA14	3448	interferon, alpha 14	extracellular region	Cellular component	-
SNX16	64089	sorting nexin 16	lysosome	Cellular component	-
SAMHD1	25939	SAM domain and HD domain 1	zinc ion binding	Molecular function	24217394
ANAPC2	29882	anaphase promoting complex subunit 2	ubiquitin protein ligase activity	Molecular function	-
ARID5B	84159	AT rich interactive domain 5B (MRF1-like)	fibroblast migration	Biological process	-
RAC1	5879	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	actin filament	Cellular component	19625648
VSX2	338917	visual system homeobox 2	cytoplasm	Cellular component	-
ADCK3	56997	aarF domain containing kinase 3	integral component of membrane	Cellular component	-
CCL15	6359	chemokine (C-C motif) ligand 15	heparin binding	Molecular function	-
HSPA1A	3303	heat shock 70kDa protein 1A	ribonucleoprotein complex	Cellular component	17289661
HIST1H3J	8356	histone cluster 1, H3j	nucleoplasm	Cellular component	-
OR2AP1	121129	olfactory receptor, family 2, subfamily AP, member 1	G-protein coupled receptor activity	Molecular function	-
PLEKHA4	57664	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4	cytoplasm	Cellular component	-
FNBP1	23048	formin binding protein 1	cell cortex	Cellular component	-
ADCY3	109	adenylate cyclase 3	plasma membrane	Cellular component	-
ZGLP1	100125288	zinc finger, GATA-like protein 1	multicellular organismal development	Biological process	-
OR6K2	81448	olfactory receptor, family 6, subfamily K, member 2	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
RAB30	27314	RAB30, member RAS oncogene family	GTP binding	Molecular function	-
TEKT3	64518	tektin 3	sperm motility	Biological process	-
DTNBP1	84062	dystrobrevin binding protein 1	nucleus	Cellular component	-
RBM10	8241	RNA binding motif protein 10	nucleotide binding	Molecular function	-
CD276	80381	CD276 molecule	positive regulation of interleukin-2 secretion	Biological process	-
AQP7	364	aquaporin 7	integral component of plasma membrane	Cellular component	9405233
CHRNA4	1137	cholinergic receptor, nicotinic, alpha 4 (neuronal)	acetylcholine binding	Molecular function	8906617
CDK5	1020	cyclin-dependent kinase 5	neuron projection development	Biological process	-
ZNF274	10782	zinc finger protein 274	regulation of transcription, DNA-templated	Biological process	10520746
CTSC	1075	cathepsin C	extracellular exosome	Cellular component	19056867
PDK3	5165	pyruvate dehydrogenase kinase, isozyme 3	regulation of reactive oxygen species metabolic process	Biological process	22865452
SLC52A3	113278	solute carrier family 52 (riboflavin transporter), member 3	sensory perception of sound	Biological process	20206331
ACTA2	59	actin, alpha 2, smooth muscle, aorta	filopodium	Cellular component	-
RPS11	6205	ribosomal protein S11	SRP-dependent cotranslational protein targeting to membrane	Biological process	-
CYP2E1	1571	cytochrome P450, family 2, subfamily E, polypeptide 1	heme binding	Molecular function	18818195
PARP1	142	poly (ADP-ribose) polymerase 1	transcription factor binding	Molecular function	19303849
UCP1	7350	uncoupling protein 1 (mitochondrial, proton carrier)	small molecule metabolic process	Biological process	-
WBSCR17	64409	Williams-Beuren syndrome chromosome region 17	carbohydrate binding	Molecular function	-
FOXO1	2308	forkhead box O1	fat cell differentiation	Biological process	22510882
SMAD7	4092	SMAD family member 7	I-SMAD binding	Molecular function	9256479
ESR1	2099	estrogen receptor 1	zinc ion binding	Molecular function	-
MRPL21	219927	mitochondrial ribosomal protein L21	mitochondrial translational initiation	Biological process	-
RPS25	6230	ribosomal protein S25	structural constituent of ribosome	Molecular function	-
SLC9A9	285195	solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9	regulation of pH	Biological process	-
CPSF3	51692	cleavage and polyadenylation specific factor 3, 73kDa	histone mRNA 3'-end processing	Biological process	18688255
C3orf52	79669	chromosome 3 open reading frame 52	integral component of membrane	Cellular component	-
PGLYRP1	8993	peptidoglycan recognition protein 1	extracellular exosome	Cellular component	19056867
KLF3	51274	Kruppel-like factor 3 (basic)	transcription, DNA-templated	Biological process	-
THAP5	168451	THAP domain containing 5	cell cycle	Biological process	-
PPARG	5468	peroxisome proliferator-activated receptor gamma	heart development	Biological process	-
PRKAR1A	5573	protein kinase, cAMP-dependent, regulatory, type I, alpha	protein kinase A catalytic subunit binding	Molecular function	21812984
SRF	6722	serum response factor (c-fos serum response element-binding transcription factor)	patterning of blood vessels	Biological process	-
FIGF	2277	c-fos induced growth factor (vascular endothelial growth factor D)	chemoattractant activity	Molecular function	19275959
NEDD4L	23327	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase	ion channel binding	Molecular function	15217910
AGRP	181	agouti related neuropeptide	response to insulin	Biological process	-
LIG1	3978	ligase I, DNA, ATP-dependent	double-strand break repair via nonhomologous end joining	Biological process	-
OR2V2	285659	olfactory receptor, family 2, subfamily V, member 2	olfactory receptor activity	Molecular function	-
CYP3A5	1577	cytochrome P450, family 3, subfamily A, polypeptide 5	small molecule metabolic process	Biological process	-
CCDC155	147872	coiled-coil domain containing 155	oogenesis	Biological process	-
PCDHB4	56131	protocadherin beta 4	plasma membrane	Cellular component	-
MTOR	2475	mechanistic target of rapamycin (serine/threonine kinase)	TFIIIC-class transcription factor binding	Molecular function	20543138
SORCS2	57537	sortilin-related VPS10 domain containing receptor 2	membrane	Cellular component	11499680
EED	8726	embryonic ectoderm development	chromatin organization	Biological process	-
QKI	9444	QKI, KH domain containing, RNA binding	myelination	Biological process	-
ZNF114	163071	zinc finger protein 114	extracellular exosome	Cellular component	19056867
SOX4	6659	SRY (sex determining region Y)-box 4	nuclear transcription factor complex	Cellular component	-
PDIA3	2923	protein disulfide isomerase family A, member 3	protein folding	Biological process	-
PROZ	8858	protein Z, vitamin K-dependent plasma glycoprotein	cellular protein metabolic process	Biological process	-
GCLM	2730	glutamate-cysteine ligase, modifier subunit	cytosol	Cellular component	-
TK2	7084	thymidine kinase 2, mitochondrial	phosphorylation	Biological process	-
PPL	5493	periplakin	cytoskeleton	Cellular component	-
UGT2B15	7366	UDP glucuronosyltransferase 2 family, polypeptide B15	cellular glucuronidation	Biological process	20056724
JMJD6	23210	jumonji domain containing 6	nucleus	Cellular component	14729065
PRKAA1	5562	protein kinase, AMP-activated, alpha 1 catalytic subunit	response to camptothecin	Biological process	-
NACA	4666	nascent polypeptide-associated complex alpha subunit	nucleus	Cellular component	21071677
PKN1	5585	protein kinase N1	endosome	Cellular component	9478917
RAB15	376267	RAB15, member RAS oncogene family	positive regulation of regulated secretory pathway	Biological process	22899725
TAF9B	51616	TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa	protein heterodimerization activity	Molecular function	-
GTF3C5	9328	general transcription factor IIIC, polypeptide 5, 63kDa	transcription factor TFIIIC complex	Cellular component	17409385
APEX2	27301	APEX nuclease (apurinic/apyrimidinic endonuclease) 2	nucleic acid phosphodiester bond hydrolysis	Biological process	-
RNF8	9025	ring finger protein 8, E3 ubiquitin protein ligase	response to ionizing radiation	Biological process	18001824
TLR5	7100	toll-like receptor 5	plasma membrane	Cellular component	-
SNRPB	6628	small nuclear ribonucleoprotein polypeptides B and B1	cytoplasm	Cellular component	-
ATF1	466	activating transcription factor 1	toll-like receptor 10 signaling pathway	Biological process	-
HIST1H4D	8360	histone cluster 1, H4d	extracellular exosome	Cellular component	19199708
ZBTB22	9278	zinc finger and BTB domain containing 22	metal ion binding	Molecular function	-
GABRG3	2567	gamma-aminobutyric acid (GABA) A receptor, gamma 3	gamma-aminobutyric acid signaling pathway	Biological process	-
GPC3	2719	glypican 3	mesenchymal cell proliferation involved in ureteric bud development	Biological process	-
C8B	732	complement component 8, beta polypeptide	extracellular vesicle	Cellular component	24769233
NFKB1	4790	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	toll-like receptor 10 signaling pathway	Biological process	-
SPDEF	25803	SAM pointed domain containing ETS transcription factor	nucleus	Cellular component	-
PSMD1	5707	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	small molecule metabolic process	Biological process	-
RBMY1D	378949	RNA binding motif protein, Y-linked, family 1, member D	nucleus	Cellular component	-
IGF2	3481	insulin-like growth factor 2	glucose metabolic process	Biological process	-
RFFL	117584	ring finger and FYVE-like domain containing E3 ubiquitin protein ligase	tumor necrosis factor receptor superfamily complex	Cellular component	18450452
POLR2J	5439	polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa	viral process	Biological process	-
DBN1	1627	drebrin 1	neural precursor cell proliferation	Biological process	-
STX17	55014	syntaxin 17	protein kinase binding	Molecular function	-
KLK8	11202	kallikrein-related peptidase 8	negative regulation of myelination	Biological process	-
PSMD13	5719	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	regulation of cellular amino acid metabolic process	Biological process	-
HDAC6	10013	histone deacetylase 6	cellular response to heat	Biological process	-
KIF13B	23303	kinesin family member 13B	metabolic process	Biological process	10859302
USH1G	124590	Usher syndrome 1G (autosomal recessive)	cytosol	Cellular component	-
FGFR2	2263	fibroblast growth factor receptor 2	positive regulation of ERK1 and ERK2 cascade	Biological process	-
ABL2	27	ABL proto-oncogene 2, non-receptor tyrosine kinase	regulation of endocytosis	Biological process	20841568
RB1	5925	retinoblastoma 1	mitotic cell cycle checkpoint	Biological process	9529249
KIT	3815	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	cellular response to thyroid hormone stimulus	Biological process	-
BCL2	596	B-cell CLL/lymphoma 2	spleen development	Biological process	-
CLN8	2055	ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)	lysosome organization	Biological process	-
PIK3AP1	118788	phosphoinositide-3-kinase adaptor protein 1	identical protein binding	Molecular function	-
SLC26A1	10861	solute carrier family 26 (anion exchanger), member 1	chloride transport	Biological process	-
TIMELESS	8914	timeless circadian clock	regulation of cell proliferation	Biological process	17102137
EPHA2	1969	EPH receptor A2	skeletal system development	Biological process	-
FGF6	2251	fibroblast growth factor 6	positive regulation of cell proliferation	Biological process	8663044
BRPF3	27154	bromodomain and PHD finger containing, 3	blood coagulation	Biological process	-
HSPA5	3309	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	nucleus	Cellular component	11943137
LIMS2	55679	LIM and senescent cell antigen-like domains 2	nucleus	Cellular component	-
INPP5K	51763	inositol polyphosphate-5-phosphatase K	actin cytoskeleton organization	Biological process	10753883
RAB11FIP5	26056	RAB11 family interacting protein 5 (class I)	early endosome	Cellular component	-
EDEM1	9695	ER degradation enhancer, mannosidase alpha-like 1	misfolded protein binding	Molecular function	19524542
OPRK1	4986	opioid receptor, kappa 1	immune response	Biological process	8755601
SLC24A1	9187	solute carrier family 24 (sodium/potassium/calcium exchanger), member 1	outer membrane	Cellular component	9856482
TAB1	10454	TGF-beta activated kinase 1/MAP3K7 binding protein 1	catalytic activity	Molecular function	-
UBE2L6	9246	ubiquitin-conjugating enzyme E2L 6	DNA repair	Biological process	-
CSTF3	1479	cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa	termination of RNA polymerase II transcription	Biological process	-
ATP2B1	490	ATPase, Ca++ transporting, plasma membrane 1	calmodulin binding	Molecular function	-
EGFL8	80864	EGF-like-domain, multiple 8	in utero embryonic development	Biological process	-
PRSS55	203074	protease, serine, 55	cytosol	Cellular component	-
UACA	55075	uveal autoantigen with coiled-coil domains and ankyrin repeats	nucleoplasm	Cellular component	-
SYTL3	94120	synaptotagmin-like 3	plasma membrane	Cellular component	-
SLC22A5	6584	solute carrier family 22 (organic cation/carnitine transporter), member 5	antibiotic transporter activity	Molecular function	-
TBX18	9096	T-box 18	positive regulation of epithelial cell proliferation	Biological process	-
SLC25A33	84275	solute carrier family 25 (pyrimidine nucleotide carrier), member 33	regulation of reactive oxygen species biosynthetic process	Biological process	20453889
TAAR9	134860	trace amine associated receptor 9 (gene/pseudogene)	G-protein coupled receptor signaling pathway	Biological process	-
TRPM4	54795	transient receptor potential cation channel, subfamily M, member 4	protein sumoylation	Biological process	19726882
BDP1	55814	B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB	transcription factor TFIIIB complex	Cellular component	-
TDO2	6999	tryptophan 2,3-dioxygenase	heme binding	Molecular function	-
CISD2	493856	CDGSH iron sulfur domain 2	mitochondrion degradation	Biological process	-
MKRN1	23608	makorin ring finger protein 1	chromatin binding	Molecular function	-
ETS1	2113	v-ets avian erythroblastosis virus E26 oncogene homolog 1	regulation of apoptotic process	Biological process	9266972
PKN2	5586	protein kinase N2	cell adhesion	Biological process	-
CSNK1D	1453	casein kinase 1, delta	ATP binding	Molecular function	-
HIST2H2AC	8338	histone cluster 2, H2ac	DNA binding	Molecular function	-
HTR2A	3356	5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled	synaptic transmission	Biological process	9109547
DAAM1	23002	dishevelled associated activator of morphogenesis 1	identical protein binding	Molecular function	16630611
MCM9	254394	minichromosome maintenance complex component 9	nucleus	Cellular component	-
FNDC3A	22862	fibronectin type III domain containing 3A	integral component of membrane	Cellular component	-
PDGFC	56034	platelet derived growth factor C	regulation of peptidyl-tyrosine phosphorylation	Biological process	-
BMP6	654	bone morphogenetic protein 6	positive regulation of aldosterone secretion	Biological process	-
ECI1	1632	enoyl-CoA delta isomerase 1	fatty acid beta-oxidation	Biological process	-
EFHD1	80303	EF-hand domain family, member D1	neuron projection development	Biological process	-
SFRP2	6423	secreted frizzled-related protein 2	negative regulation of cardiac muscle cell apoptotic process	Biological process	-
MGAT1	4245	mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	carbohydrate metabolic process	Biological process	1702225
DAG1	1605	dystroglycan 1 (dystrophin-associated glycoprotein 1)	dystroglycan binding	Molecular function	-
FLCN	201163	folliculin	positive regulation of cell adhesion	Biological process	21209915
TWIST1	7291	twist family bHLH transcription factor 1	negative regulation of osteoblast differentiation	Biological process	16888803
AP1M1	8907	adaptor-related protein complex 1, mu 1 subunit	trans-Golgi network membrane	Cellular component	-
ZXDC	79364	ZXD family zinc finger C	LRR domain binding	Molecular function	16600381
CMTM5	116173	CKLF-like MARVEL transmembrane domain containing 5	cytokine activity	Molecular function	-
WAPAL	23063	wings apart-like homolog (Drosophila)	cell division	Biological process	-
EXOC5	10640	exocyst complex component 5	cellular protein metabolic process	Biological process	-
ACER1	125981	alkaline ceramidase 1	regulation of lipid metabolic process	Biological process	-
ESR1	2099	estrogen receptor 1	epithelial cell development	Biological process	-
NPR1	4881	natriuretic peptide receptor 1	receptor complex	Cellular component	23382219
PTPRZ1	5803	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	proteinaceous extracellular matrix	Cellular component	-
KCNN4	3783	potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4	stabilization of membrane potential	Biological process	18796614
AKR1C1	1645	aldo-keto reductase family 1, member C1	bile acid metabolic process	Biological process	8486699
HAND2	9464	heart and neural crest derivatives expressed 2	sympathetic nervous system development	Biological process	-
APOD	347	apolipoprotein D	perinuclear region of cytoplasm	Cellular component	14551159
SNX7	51375	sorting nexin 7	extrinsic component of membrane	Cellular component	-
IL6R	3570	interleukin 6 receptor	interleukin-6 receptor binding	Molecular function	12829785
POLR2J2	246721	polymerase (RNA) II (DNA directed) polypeptide J2	DNA-directed RNA polymerase activity	Molecular function	-
BHMT	635	betaine--homocysteine S-methyltransferase	zinc ion binding	Molecular function	18230605
PES1	23481	pescadillo ribosomal biogenesis factor 1	poly(A) RNA binding	Molecular function	22658674
MDH2	4191	malate dehydrogenase 2, NAD (mitochondrial)	gluconeogenesis	Biological process	-
SDHB	6390	succinate dehydrogenase complex, subunit B, iron sulfur (Ip)	succinate metabolic process	Biological process	-
CAMK2N1	55450	calcium/calmodulin-dependent protein kinase II inhibitor 1	cell junction	Cellular component	-
EXOC3	11336	exocyst complex component 3	organelle organization	Biological process	-
SOX9	6662	SRY (sex determining region Y)-box 9	negative regulation of bone mineralization	Biological process	-
TRERF1	55809	transcriptional regulating factor 1	steroid biosynthetic process	Biological process	11349124
TAF10	6881	TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa	transcription coactivator activity	Molecular function	11564863
PCM1	5108	pericentriolar material 1	protein binding	Molecular function	14520415
WNT3A	89780	wingless-type MMTV integration site family, member 3A	cell surface	Cellular component	-
F8A1	8263	coagulation factor VIII-associated 1	molecular_function	Molecular function	-
PARD3	56288	par-3 family cell polarity regulator	cell-cell adherens junction	Cellular component	-
IGHMBP2	3508	immunoglobulin mu binding protein 2	transcription factor binding	Molecular function	19299493
TOP1MT	116447	topoisomerase (DNA) I, mitochondrial	DNA topoisomerase type I activity	Molecular function	-
IFNA2	3440	interferon, alpha 2	protein binding	Molecular function	7759950
ADCY7	113	adenylate cyclase 7	adenylate cyclase-activating G-protein coupled receptor signaling pathway	Biological process	-
SLC6A6	6533	solute carrier family 6 (neurotransmitter transporter), member 6	amino acid transport	Biological process	-
AOC2	314	amine oxidase, copper containing 2 (retina-specific)	aliphatic-amine oxidase activity	Molecular function	-
CYP17A1	1586	cytochrome P450, family 17, subfamily A, polypeptide 1	steroid 17-alpha-monooxygenase activity	Molecular function	22170710
SORBS3	10174	sorbin and SH3 domain containing 3	focal adhesion	Cellular component	9885244
CDCA8	55143	cell division cycle associated 8	nucleolus	Cellular component	-
DNAJB2	3300	DnaJ (Hsp40) homolog, subfamily B, member 2	negative regulation of cell growth	Biological process	9553041
UCHL1	7345	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)	alpha-2A adrenergic receptor binding	Molecular function	19477270
CRHR1	1394	corticotropin releasing hormone receptor 1	adrenal gland development	Biological process	-
MARVELD1	83742	MARVEL domain containing 1	cell cycle	Biological process	-
ADRB2	154	adrenoceptor beta 2, surface	regulation of sodium ion transport	Biological process	-
TGFB2	7042	transforming growth factor, beta 2	heart morphogenesis	Biological process	10092230
MSX1	4487	msh homeobox 1	negative regulation of cell growth	Biological process	15705871
DCAF4	26094	DDB1 and CUL4 associated factor 4	Cul4-RING E3 ubiquitin ligase complex	Cellular component	16949367
RFWD2	64326	ring finger and WD repeat domain 2, E3 ubiquitin protein ligase	zinc ion binding	Molecular function	-
RNF2	6045	ring finger protein 2	protein sumoylation	Biological process	-
FZD2	2535	frizzled class receptor 2	PDZ domain binding	Molecular function	19388021
SKIV2L2	23517	superkiller viralicidic activity 2-like 2 (S. cerevisiae)	exosome (RNase complex)	Cellular component	11719186
ERAL1	26284	Era-like 12S mitochondrial rRNA chaperone 1	GTP binding	Molecular function	-
PFKM	5213	phosphofructokinase, muscle	ATP binding	Molecular function	8780720
STH	246744	saitohin	nucleus	Cellular component	-
OGG1	4968	8-oxoguanine DNA glycosylase	endonuclease activity	Molecular function	9223305
BMX	660	BMX non-receptor tyrosine kinase	extrinsic component of cytoplasmic side of plasma membrane	Cellular component	-
FER	2241	fer (fps/fes related) tyrosine kinase	Kit signaling pathway	Biological process	-
RP2	6102	retinitis pigmentosa 2 (X-linked recessive)	GTP binding	Molecular function	-
ARPC5	10092	actin related protein 2/3 complex, subunit 5, 16kDa	structural constituent of cytoskeleton	Molecular function	11741539
TOR1B	27348	torsin family 1, member B (torsin B)	response to unfolded protein	Biological process	10644435
S100A8	6279	S100 calcium binding protein A8	leukocyte migration involved in inflammatory response	Biological process	12626582
AZIN2	113451	antizyme inhibitor 2	dendrite	Cellular component	19832840
CDK16	5127	cyclin-dependent kinase 16	growth hormone secretion	Biological process	-
FGFR3	2261	fibroblast growth factor receptor 3	endochondral bone growth	Biological process	15748888
GPBP1	65056	GC-rich promoter binding protein 1	plasma membrane	Cellular component	-
SST	6750	somatostatin	extracellular region	Cellular component	-
CASP2	835	caspase 2, apoptosis-related cysteine peptidase	enzyme binding	Molecular function	11076957
DDX46	9879	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46	RNA secondary structure unwinding	Biological process	-
CISD1	55847	CDGSH iron sulfur domain 1	mitochondrion	Cellular component	-
EPHB3	2049	EPH receptor B3	cytosol	Cellular component	-
ABHD14B	84836	abhydrolase domain containing 14B	nucleolus	Cellular component	-
CPNE4	131034	copine IV	extracellular exosome	Cellular component	23533145
TNFSF4	7292	tumor necrosis factor (ligand) superfamily, member 4	acute inflammatory response	Biological process	-
BRSK1	84446	BR serine/threonine kinase 1	response to UV	Biological process	15150265
CA6	765	carbonic anhydrase VI	zinc ion binding	Molecular function	-
FOXS1	2307	forkhead box S1	sequence-specific DNA binding RNA polymerase II transcription factor activity	Molecular function	-
SMARCA5	8467	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	NURF complex	Cellular component	20850016
PDLIM1	9124	PDZ and LIM domain 1	response to oxidative stress	Biological process	8522188
LDLRAP1	26119	low density lipoprotein receptor adaptor protein 1	beta-amyloid binding	Molecular function	12805363
HK1	3098	hexokinase 1	transmembrane transport	Biological process	-
MEF2C	4208	myocyte enhancer factor 2C	cardiac ventricle formation	Biological process	-
SCG2	7857	secretogranin II	MAPK cascade	Biological process	14970115
E2F3	1871	E2F transcription factor 3	Golgi apparatus	Cellular component	-
XRCC5	7520	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	positive regulation of type I interferon production	Biological process	-
SNW1	22938	SNW domain containing 1	positive transcription elongation factor complex b	Cellular component	15905409
NRCAM	4897	neuronal cell adhesion molecule	neuron migration	Biological process	11483367
ACTG1	71	actin gamma 1	cell junction assembly	Biological process	-
FGR	2268	FGR proto-oncogene, Src family tyrosine kinase	ATP binding	Molecular function	-
ZCCHC11	23318	zinc finger, CCHC domain containing 11	stem cell maintenance	Biological process	19703396
PLEKHA8	84725	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8	glycolipid binding	Molecular function	17687330
NRSN1	140767	neurensin 1	neuronal cell body	Cellular component	-
WDR4	10785	WD repeat domain 4	tRNA (guanine-N7-)-methyltransferase activity	Molecular function	12403464
DOCK2	1794	dedicator of cytokinesis 2	positive thymic T cell selection	Biological process	-
CORO1C	23603	coronin, actin binding protein, 1C	lamellipodium	Cellular component	22364218
WNT1	7471	wingless-type MMTV integration site family, member 1	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	-
CSRNP2	81566	cysteine-serine-rich nuclear protein 2	protein binding	Molecular function	15231748
ARAP3	64411	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	phosphatidylinositol-3,4-bisphosphate binding	Molecular function	11804589
TOR1AIP2	163590	torsin A interacting protein 2	endoplasmic reticulum organization	Biological process	24275647
RAB36	9609	RAB36, member RAS oncogene family	Golgi membrane	Cellular component	-
TNMD	64102	tenomodulin	nuclear envelope	Cellular component	-
PRKCA	5578	protein kinase C, alpha	positive regulation of inflammatory response	Biological process	-
CSNK2A1	1457	casein kinase 2, alpha 1 polypeptide	positive regulation of Wnt signaling pathway	Biological process	12700239
WWP1	11059	WW domain containing E3 ubiquitin protein ligase 1	cytoplasm	Cellular component	-
ACP5	54	acid phosphatase 5, tartrate resistant	ferrous iron binding	Molecular function	15993892
ADGRB1	575	adhesion G protein-coupled receptor B1	negative regulation of angiogenesis	Biological process	-
PUS7	54517	pseudouridylate synthase 7 (putative)	pseudouridine synthesis	Biological process	-
ZW10	9183	zw10 kinetochore protein	kinetochore	Cellular component	11682612
GPIHBP1	338328	glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1	basolateral plasma membrane	Cellular component	20620994
OR8H3	390152	olfactory receptor, family 8, subfamily H, member 3	sensory perception of smell	Biological process	-
NIPAL4	348938	NIPA-like domain containing 4	integral component of membrane	Cellular component	-
TOP3A	7156	topoisomerase (DNA) III alpha	protein binding	Molecular function	10728666
MYH11	4629	myosin, heavy chain 11, smooth muscle	cardiac muscle fiber development	Biological process	16444274
HOMER1	9456	homer scaffolding protein 1	scaffold protein binding	Molecular function	-
CREBBP	1387	CREB binding protein	RNA polymerase II transcription factor binding	Molecular function	21539536
DYNLT3	6990	dynein, light chain, Tctex-type 3	nucleus	Cellular component	-
LGALS2	3957	lectin, galactoside-binding, soluble, 2	protein binding	Molecular function	25416956
NOS1	4842	nitric oxide synthase 1 (neuronal)	synapse	Cellular component	-
NAPSA	9476	napsin A aspartic peptidase	membrane protein proteolysis	Biological process	14766755
HPS1	3257	Hermansky-Pudlak syndrome 1	retina development in camera-type eye	Biological process	-
PTK2	5747	protein tyrosine kinase 2	regulation of cell proliferation	Biological process	18206965
PSMC3	5702	proteasome (prosome, macropain) 26S subunit, ATPase, 3	blastocyst development	Biological process	-
SPOP	8405	speckle-type POZ protein	nucleoplasm	Cellular component	-
HIF1A	3091	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	heart looping	Biological process	-
MAPK1	5594	mitogen-activated protein kinase 1	activation of MAPK activity	Biological process	-
HCK	3055	HCK proto-oncogene, Src family tyrosine kinase	inflammatory response	Biological process	-
HEY2	23493	hes-related family bHLH transcription factor with YRPW motif 2	negative regulation of transcription, DNA-templated	Biological process	12535671
FOS	2353	FBJ murine osteosarcoma viral oncogene homolog	innate immune response	Biological process	-
PRKDC	5591	protein kinase, DNA-activated, catalytic polypeptide	double-strand break repair via homologous recombination	Biological process	-
KRT222	125113	keratin 222, type II	intermediate filament	Cellular component	-
RPS12	6206	ribosomal protein S12	poly(A) RNA binding	Molecular function	22658674
CITED2	10370	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	regulation of organ formation	Biological process	-
ALDH1A1	216	aldehyde dehydrogenase 1 family, member A1	retinol metabolic process	Biological process	-
IFI6	2537	interferon, alpha-inducible protein 6	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	Biological process	15685448
CDADC1	81602	cytidine and dCMP deaminase domain containing 1	metabolic process	Biological process	-
CAD	790	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	'de novo' pyrimidine nucleobase biosynthetic process	Biological process	-
TGIF1	7050	TGFB-induced factor homeobox 1	negative regulation of retinoic acid receptor signaling pathway	Biological process	-
RICTOR	253260	RPTOR independent companion of MTOR, complex 2	regulation of protein kinase B signaling	Biological process	15718470
LSM6	11157	LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	Biological process	-
PDE6G	5148	phosphodiesterase 6G, cGMP-specific, rod, gamma	photoreceptor disc membrane	Cellular component	-
CHEK2	11200	checkpoint kinase 2	DNA damage checkpoint	Biological process	10617473
FMN1	342184	formin 1	actin binding	Molecular function	-
TAB3	257397	TGF-beta activated kinase 1/MAP3K7 binding protein 3	cytoplasm	Cellular component	-
RAB18	22931	RAB18, member RAS oncogene family	extracellular exosome	Cellular component	23376485
ADRA1B	147	adrenoceptor alpha 1B	adenylate cyclase-modulating G-protein coupled receptor signaling pathway	Biological process	10820200
Sep-04	5414	septin 4	structural molecule activity	Molecular function	9889007
EP300	2033	E1A binding protein p300	Notch signaling pathway	Biological process	-
ACTN3	89	actinin, alpha 3 (gene/pseudogene)	actin filament	Cellular component	1339456
ZNF10	7556	zinc finger protein 10	DNA binding	Molecular function	-
SP140	11262	SP140 nuclear body protein	PML body	Cellular component	-
RRAGC	64121	Ras-related GTP binding C	GTPase activity	Molecular function	11073942
ADAMTS3	9508	ADAM metallopeptidase with thrombospondin type 1 motif, 3	extracellular region	Cellular component	-
PIM1	5292	Pim-1 proto-oncogene, serine/threonine kinase	negative regulation of sequence-specific DNA binding transcription factor activity	Biological process	18593906
PSMC5	5705	proteasome (prosome, macropain) 26S subunit, ATPase, 5	gene expression	Biological process	-
GPC3	2719	glypican 3	chondroitin sulfate metabolic process	Biological process	-
DPCR1	135656	diffuse panbronchiolitis critical region 1	positive regulation of protein targeting to mitochondrion	Biological process	24270810
HIST1H3H	8357	histone cluster 1, H3h	nuclear nucleosome	Cellular component	20498094
OR2T29	343563	olfactory receptor, family 2, subfamily T, member 29	G-protein coupled receptor activity	Molecular function	-
RAB6C	84084	RAB6C, member RAS oncogene family	intracellular	Cellular component	10455022
WDR61	80349	WD repeat domain 61	positive regulation of transcription elongation from RNA polymerase II promoter	Biological process	20178742
ZBTB18	10472	zinc finger and BTB domain containing 18	transcription, DNA-templated	Biological process	-
PHB2	11331	prohibitin 2	negative regulation of transcription, DNA-templated	Biological process	10359819
SYT4	6860	synaptotagmin IV	intracellular membrane-bounded organelle	Cellular component	-
BHMT2	23743	betaine--homocysteine S-methyltransferase 2	zinc ion binding	Molecular function	18230605
GPIHBP1	338328	glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1	chylomicron binding	Molecular function	19304573
SPOP	8405	speckle-type POZ protein	Cul3-RING ubiquitin ligase complex	Cellular component	22085717
PDE4D	5144	phosphodiesterase 4D, cAMP-specific	regulation of protein kinase A signaling	Biological process	-
TBL1XR1	79718	transducin (beta)-like 1 X-linked receptor 1	nucleoplasm	Cellular component	-
OARD1	221443	O-acyl-ADP-ribose deacylase 1	deacetylase activity	Molecular function	21849506
HIST1H2BB	3018	histone cluster 1, H2bb	nucleus	Cellular component	16319397
GATA3	2625	GATA binding protein 3	thymic T cell selection	Biological process	-
TCN2	6948	transcobalamin II	cobalt ion transport	Biological process	-
CEP57L1	285753	centrosomal protein 57kDa-like 1	identical protein binding	Molecular function	-
KIAA0368	23392	KIAA0368	cytoplasmic membrane-bounded vesicle	Cellular component	15496406
LUM	4060	lumican	extracellular matrix organization	Biological process	-
RHOQ	23433	ras homolog family member Q	extracellular exosome	Cellular component	23533145
SH2D1B	117157	SH2 domain containing 1B	leukocyte activation involved in immune response	Biological process	-
CYP4F12	66002	cytochrome P450, family 4, subfamily F, polypeptide 12	heme binding	Molecular function	-
G6PD	2539	glucose-6-phosphate dehydrogenase	cytoplasm	Cellular component	-
HELT	391723	helt bHLH transcription factor	transcription, DNA-templated	Biological process	-
BRF1	2972	BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit	transcription initiation from RNA polymerase III promoter	Biological process	-
MAML1	9794	mastermind-like 1 (Drosophila)	nuclear speck	Cellular component	-
CBX8	57332	chromobox homolog 8	protein sumoylation	Biological process	-
SLC6A9	6536	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	membrane	Cellular component	8183239
RAB1A	5861	RAB1A, member RAS oncogene family	interleukin-8 secretion	Biological process	22939626
PTCH1	5727	patched 1	branching involved in ureteric bud morphogenesis	Biological process	-
SLC25A46	91137	solute carrier family 25, member 46	integral component of membrane	Cellular component	-
FOXA3	3171	forkhead box A3	transcription regulatory region DNA binding	Molecular function	12695546
PRM3	58531	protamine 3	spermatogenesis	Biological process	-
RNF26	79102	ring finger protein 26	cellular_component	Cellular component	-
GATA4	2626	GATA binding protein 4	response to drug	Biological process	20585342
CYBRD1	79901	cytochrome b reductase 1	cellular iron ion homeostasis	Biological process	-
ERC1	23085	ELKS/RAB6-interacting/CAST family member 1	I-kappaB phosphorylation	Biological process	15218148
ABCA1	19	ATP-binding cassette, sub-family A (ABC1), member 1	phagocytosis, engulfment	Biological process	-
HTR2C	3358	5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled	behavioral fear response	Biological process	-
ZNF846	162993	zinc finger protein 846	protein binding	Molecular function	25416956
ILF3	3609	interleukin enhancer binding factor 3, 90kDa	DNA binding	Molecular function	10574923
IGF1	3479	insulin-like growth factor 1 (somatomedin C)	regulation of gene expression	Biological process	21543511
SGTB	54557	small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta	protein binding	Molecular function	16189514
SLC35A2	7355	solute carrier family 35 (UDP-galactose transporter), member A2	integral component of membrane	Cellular component	-
PPP1R13B	23368	protein phosphatase 1, regulatory subunit 13B	plasma membrane	Cellular component	-
BCL10	8915	B-cell CLL/lymphoma 10	protein oligomerization	Biological process	14695475
DAB1	1600	Dab, reelin signal transducer, homolog 1 (Drosophila)	radial glia guided migration of Purkinje cell	Biological process	-
TYMP	1890	thymidine phosphorylase	chemotaxis	Biological process	-
HHAT	55733	hedgehog acyltransferase	smoothened signaling pathway	Biological process	-
CUL3	8452	cullin 3	positive regulation of cytokinesis	Biological process	19261606
ONECUT1	3175	one cut homeobox 1	endoderm development	Biological process	-
TPD52L1	7164	tumor protein D52-like 1	protein heterodimerization activity	Molecular function	9484778
TINAGL1	64129	tubulointerstitial nephritis antigen-like 1	polysaccharide binding	Molecular function	-
ALKBH1	8846	alkB, alkylation repair homolog 1 (E. coli)	RNA repair	Biological process	18603530
TENM1	10178	teneurin transmembrane protein 1	nervous system development	Biological process	10341219
FOXF2	2295	forkhead box F2	embryonic camera-type eye morphogenesis	Biological process	-
GPC1	2817	glypican 1	Schwann cell differentiation	Biological process	-
TTN	7273	titin	Z disc	Cellular component	11717165
C9orf142	286257	chromosome 9 open reading frame 142	DNA ligation involved in DNA repair	Biological process	25574025
RARB	5915	retinoic acid receptor, beta	steroid hormone mediated signaling pathway	Biological process	-
DACT1	51339	dishevelled-binding antagonist of beta-catenin 1	negative regulation of canonical Wnt signaling pathway	Biological process	-
SNCA	6622	synuclein, alpha (non A4 component of amyloid precursor)	dopamine biosynthetic process	Biological process	21320589
TAB2	23118	TGF-beta activated kinase 1/MAP3K7 binding protein 2	activation of MAPK activity	Biological process	-
LRPAP1	4043	low density lipoprotein receptor-related protein associated protein 1	protein binding	Molecular function	8083232
KDELR2	11014	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2	KDEL sequence binding	Molecular function	1316805
STRN4	29888	striatin, calmodulin binding protein 4	protein phosphatase 2A binding	Molecular function	18782753
FAM69C	125704	family with sequence similarity 69, member C	transferase activity, transferring phosphorus-containing groups	Molecular function	-
IL10	3586	interleukin 10	negative regulation of interleukin-6 production	Biological process	10443688
MGAT4B	11282	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B	cellular protein metabolic process	Biological process	-
RAB1A	5861	RAB1A, member RAS oncogene family	establishment of endothelial intestinal barrier	Biological process	23885123
C2CD5	9847	C2 calcium-dependent domain containing 5	positive regulation of protein targeting to membrane	Biological process	21907143
CXCL11	6373	chemokine (C-X-C motif) ligand 11	positive regulation of leukocyte chemotaxis	Biological process	-
WRN	7486	Werner syndrome, RecQ helicase-like	magnesium ion binding	Molecular function	16622405
PSMF1	9491	proteasome (prosome, macropain) inhibitor subunit 1 (PI31)	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
GTF3C4	9329	general transcription factor IIIC, polypeptide 4, 90kDa	protein binding	Molecular function	17409385
SPOP	8405	speckle-type POZ protein	nucleus	Cellular component	22085717
ZMYND11	10771	zinc finger, MYND-type containing 11	methylated histone binding	Molecular function	-
SHROOM4	57477	shroom family member 4	cell morphogenesis	Biological process	16684770
KDM6B	23135	lysine (K)-specific demethylase 6B	protein binding	Molecular function	21841772
ADAMTS12	81792	ADAM metallopeptidase with thrombospondin type 1 motif, 12	regulation of inflammatory response	Biological process	23019333
CDCA5	113130	cell division cycle associated 5	regulation of cohesin localization to chromatin	Biological process	17349791
MAP2K5	5607	mitogen-activated protein kinase kinase 5	peptidyl-tyrosine phosphorylation	Biological process	-
LRP6	4040	low density lipoprotein receptor-related protein 6	extracellular region	Cellular component	-
KIF2A	3796	kinesin heavy chain member 2A	centrosome	Cellular component	21399614
CASKIN1	57524	CASK interacting protein 1	cytoplasm	Cellular component	12040031
SMN2	6607	survival of motor neuron 2, centromeric	gene expression	Biological process	-
TNIP2	79155	TNFAIP3 interacting protein 2	negative regulation of endothelial cell apoptotic process	Biological process	12933576
FADS1	3992	fatty acid desaturase 1	unsaturated fatty acid biosynthetic process	Biological process	-
NRP2	8828	neuropilin 2	integral component of membrane	Cellular component	11112349
NRL	4901	neural retina leucine zipper	protein binding	Molecular function	10887186
KRTAP9-4	85280	keratin associated protein 9-4	protein binding	Molecular function	25416956
PLD1	5337	phospholipase D1, phosphatidylcholine-specific	inositol lipid-mediated signaling	Biological process	-
ZNF461	92283	zinc finger protein 461	DNA binding	Molecular function	-
PIK3C3	5289	phosphatidylinositol 3-kinase, catalytic subunit type 3	macroautophagy	Biological process	-
CACNG2	10369	calcium channel, voltage-dependent, gamma subunit 2	neuromuscular junction development	Biological process	-
TGFA	7039	transforming growth factor, alpha	cell proliferation	Biological process	10861448
VSIG8	391123	V-set and immunoglobulin domain containing 8	integral component of membrane	Cellular component	-
N4BP1	9683	NEDD4 binding protein 1	cellular response to UV	Biological process	17592138
MTNR1A	4543	melatonin receptor 1A	organic cyclic compound binding	Molecular function	10531408
TMEM115	11070	transmembrane protein 115	Golgi transport complex	Cellular component	24806965
SRF	6722	serum response factor (c-fos serum response element-binding transcription factor)	transcription from RNA polymerase II promoter	Biological process	3203386
KLHL8	57563	kelch-like family member 8	protein ubiquitination	Biological process	19158078
SPRR2B	6701	small proline-rich protein 2B	epidermis development	Biological process	8325635
NCKAP1L	3071	NCK-associated protein 1-like	B cell homeostasis	Biological process	-
TCF12	6938	transcription factor 12	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	11802795
AP3D1	8943	adaptor-related protein complex 3, delta 1 subunit	positive regulation of NK T cell differentiation	Biological process	-
TTLL7	79739	tubulin tyrosine ligase-like family member 7	ligase activity	Molecular function	-
ACAD10	80724	acyl-CoA dehydrogenase family, member 10	acyl-CoA dehydrogenase activity	Molecular function	-
RSC1A1	6248	regulatory solute carrier protein, family 1, member 1	Golgi apparatus	Cellular component	-
POLR2L	5441	polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa	DNA-directed RNA polymerase activity	Molecular function	8524256
ELOVL1	64834	ELOVL fatty acid elongase 1	membrane	Cellular component	19946888
CLDN6	9074	claudin 6	integral component of membrane	Cellular component	-
ZNF219	51222	zinc finger protein 219	regulation of transcription, DNA-templated	Biological process	19549071
SAT1	6303	spermidine/spermine N1-acetyltransferase 1	spermidine acetylation	Biological process	-
IL13	3596	interleukin 13	immune response	Biological process	-
MERTK	10461	MER proto-oncogene, tyrosine kinase	negative regulation of lymphocyte activation	Biological process	-
KIAA0430	9665	KIAA0430	molecular_function	Molecular function	-
TGFBR1	7046	transforming growth factor, beta receptor 1	positive regulation of endothelial cell proliferation	Biological process	-
ZNF532	55205	zinc finger protein 532	metal ion binding	Molecular function	-
UCN	7349	urocortin	positive regulation of translation	Biological process	-
WWTR1	25937	WW domain containing transcription regulator 1	negative regulation of protein phosphorylation	Biological process	20412773
IGF2BP2	10644	insulin-like growth factor 2 mRNA binding protein 2	protein binding	Molecular function	12674497
SLC30A2	7780	solute carrier family 30 (zinc transporter), member 2	zinc II ion transport	Biological process	-
KDSR	2531	3-ketodihydrosphingosine reductase	3-dehydrosphinganine reductase activity	Molecular function	15364918
NAB2	4665	NGFI-A binding protein 2 (EGR1 binding protein 2)	endochondral ossification	Biological process	-
KCNQ3	3786	potassium channel, voltage gated KQT-like subfamily Q, member 3	node of Ranvier	Cellular component	16525039
TP53BP2	7159	tumor protein p53 binding protein 2	signal transduction	Biological process	9748285
STH	246744	saitohin	cytoplasm	Cellular component	-
SULF2	55959	sulfatase 2	positive regulation of vascular endothelial growth factor production	Biological process	-
CPS1	1373	carbamoyl-phosphate synthase 1, mitochondrial	mitochondrial matrix	Cellular component	-
ANK2	287	ankyrin 2, neuronal	protein binding, bridging	Molecular function	-
CD8BP	927	CD8b molecule pseudogene	plasma membrane	Cellular component	-
FUBP3	8939	far upstream element (FUSE) binding protein 3	positive regulation of transcription, DNA-templated	Biological process	8940189
INCA1	388324	inhibitor of CDK, cyclin A1 interacting protein 1	protein binding	Molecular function	21874239
SPRTN	83932	SprT-like N-terminal domain	response to UV	Biological process	22681887
SLN	6588	sarcolipin	protein binding	Molecular function	25416956
C2CD3	26005	C2 calcium-dependent domain containing 3	centriole	Cellular component	23769972
SLC7A3	84889	solute carrier family 7 (cationic amino acid transporter, y+ system), member 3	L-arginine import across plasma membrane	Biological process	-
GPR33	2856	G protein-coupled receptor 33 (gene/pseudogene)	plasma membrane	Cellular component	-
SSTR2	6752	somatostatin receptor 2	cerebellum development	Biological process	-
RRAGC	64121	Ras-related GTP binding C	cellular response to amino acid stimulus	Biological process	-
RNF208	727800	ring finger protein 208	cytoplasm	Cellular component	-
SCAMP5	192683	secretory carrier membrane protein 5	SNARE complex	Cellular component	19234194
SLC22A17	51310	solute carrier family 22, member 17	siderophore transport	Biological process	-
AKAP13	11214	A kinase (PRKA) anchor protein 13	regulation of glucocorticoid mediated signaling pathway	Biological process	-
PRKACG	5568	protein kinase, cAMP-dependent, catalytic, gamma	glucose metabolic process	Biological process	-
POLR1C	9533	polymerase (RNA) I polypeptide C, 30kDa	protein dimerization activity	Molecular function	-
DTHD1	401124	death domain containing 1	nucleus	Cellular component	-
EIF5B	9669	eukaryotic translation initiation factor 5B	cytoplasm	Cellular component	12426392
NPC2	10577	Niemann-Pick disease, type C2	cholesterol binding	Molecular function	17018531
CDK5	1020	cyclin-dependent kinase 5	synaptic vesicle endocytosis	Biological process	21473899
PSMD3	5709	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	nucleoplasm	Cellular component	-
ATXN1	6310	ataxin 1	cytoplasm	Cellular component	-
TXN	7295	thioredoxin	transcription initiation from RNA polymerase II promoter	Biological process	-
MUC19	283463	mucin 19, oligomeric	cellular protein metabolic process	Biological process	-
PTPMT1	114971	protein tyrosine phosphatase, mitochondrial 1	phosphatidylglycerol biosynthetic process	Biological process	-
TTR	7276	transthyretin	extracellular exosome	Cellular component	23376485
PDGFRA	5156	platelet-derived growth factor receptor, alpha polypeptide	regulation of mesenchymal stem cell differentiation	Biological process	21596750
CIDEA	1149	cell death-inducing DFFA-like effector a	mitochondrion	Cellular component	-
AIF1	199	allograft inflammatory factor 1	negative regulation of smooth muscle cell proliferation	Biological process	22116621
SLC32A1	140679	solute carrier family 32 (GABA vesicular transporter), member 1	neurotransmitter secretion	Biological process	-
IFT172	26160	intraflagellar transport 172	palate development	Biological process	-
SMIM23	644994	small integral membrane protein 23	integral component of membrane	Cellular component	-
TICAM1	148022	toll-like receptor adaptor molecule 1	toll-like receptor signaling pathway	Biological process	-
TRERF1	55809	transcriptional regulating factor 1	nucleus	Cellular component	11349124
NPEPPS	9520	aminopeptidase puromycin sensitive	antigen processing and presentation of peptide antigen via MHC class I	Biological process	-
CCL26	10344	chemokine (C-C motif) ligand 26	inflammatory response	Biological process	-
FGF19	9965	fibroblast growth factor 19	innate immune response	Biological process	-
APOE	348	apolipoprotein E	small molecule metabolic process	Biological process	-
ZSCAN22	342945	zinc finger and SCAN domain containing 22	transcription, DNA-templated	Biological process	-
PDC	5132	phosducin	phospholipase inhibitor activity	Molecular function	7961975
PPP1R16A	84988	protein phosphatase 1, regulatory subunit 16A	protein binding	Molecular function	16169070
EXOC7	23265	exocyst complex component 7	regulation of entry of bacterium into host cell	Biological process	20579884
POT1	25913	protection of telomeres 1	telomere capping	Biological process	15657433
DLG4	1742	discs, large homolog 4 (Drosophila)	protein complex binding	Molecular function	-
TGFB1	7040	transforming growth factor, beta 1	regulatory T cell differentiation	Biological process	-
L3MBTL1	26013	l(3)mbt-like 1 (Drosophila)	chromatin	Cellular component	18408754
EID2	163126	EP300 interacting inhibitor of differentiation 2	regulation of transforming growth factor beta receptor signaling pathway	Biological process	14612439
SLC30A5	64924	solute carrier family 30 (zinc transporter), member 5	transmembrane transport	Biological process	-
GATA3	2625	GATA binding protein 3	regulation of neuron projection development	Biological process	-
GOLGA1	2800	golgin A1	intracellular membrane-bounded organelle	Cellular component	-
TEF	7008	thyrotrophic embryonic factor	nucleus	Cellular component	-
GAS1	2619	growth arrest-specific 1	odontogenesis	Biological process	-
MAGOH	4116	mago-nashi homolog, proliferation-associated (Drosophila)	regulation of alternative mRNA splicing, via spliceosome	Biological process	22203037
PRKCB	5579	protein kinase C, beta	extracellular exosome	Cellular component	20458337
HNRNPH2	3188	heterogeneous nuclear ribonucleoprotein H2 (H')	poly(A) RNA binding	Molecular function	22658674
CDK1	983	cyclin-dependent kinase 1	nucleus	Cellular component	-
FSTL3	10272	follistatin-like 3 (secreted glycoprotein)	nucleus	Cellular component	16150905
PSMB7	5695	proteasome (prosome, macropain) subunit, beta type, 7	extracellular exosome	Cellular component	23376485
TEF	7008	thyrotrophic embryonic factor	protein heterodimerization activity	Molecular function	-
TSEN34	79042	TSEN34 tRNA splicing endonuclease subunit	RNA phosphodiester bond hydrolysis, endonucleolytic	Biological process	-
SMO	6608	smoothened, frizzled class receptor	odontogenesis of dentin-containing tooth	Biological process	-
SRSF9	8683	serine/arginine-rich splicing factor 9	RNA splicing	Biological process	-
RAB25	57111	RAB25, member RAS oncogene family	Rab protein signal transduction	Biological process	-
CEP152	22995	centrosomal protein 152kDa	centriole replication	Biological process	-
CHRNA10	57053	cholinergic receptor, nicotinic, alpha 10 (neuronal)	membrane	Cellular component	11350119
PLCG2	5336	phospholipase C, gamma 2 (phosphatidylinositol-specific)	stimulatory C-type lectin receptor signaling pathway	Biological process	-
SCX	642658	scleraxis basic helix-loop-helix transcription factor	positive regulation of gastrulation	Biological process	-
GTF2H1	2965	general transcription factor IIH, polypeptide 1, 62kDa	holo TFIIH complex	Cellular component	9852112
C9orf142	286257	chromosome 9 open reading frame 142	nucleus	Cellular component	25574025
TPCN2	219931	two pore segment channel 2	integral component of membrane	Cellular component	-
ACTN2	88	actinin, alpha 2	focal adhesion	Cellular component	16807302
SYCE1	93426	synaptonemal complex central element protein 1	protein binding	Molecular function	25416956
TRMT44	152992	tRNA methyltransferase 44 homolog (S. cerevisiae)	metal ion binding	Molecular function	-
PRKCD	5580	protein kinase C, delta	positive regulation of ceramide biosynthetic process	Biological process	19279011
WDFY2	115825	WD repeat and FYVE domain containing 2	metal ion binding	Molecular function	-
HSD17B6	8630	hydroxysteroid (17-beta) dehydrogenase 6	early endosome membrane	Cellular component	-
AXIN1	8312	axin 1	axial mesoderm formation	Biological process	-
CAMK2B	816	calcium/calmodulin-dependent protein kinase II beta	spindle midzone	Cellular component	-
RAPGEF3	10411	Rap guanine nucleotide exchange factor (GEF) 3	regulation of histone H3-K9 acetylation	Biological process	23867755
RANBP17	64901	RAN binding protein 17	cytoplasm	Cellular component	-
PTP4A3	11156	protein tyrosine phosphatase type IVA, member 3	endothelial cell migration	Biological process	24403062
ATF4	468	activating transcription factor 4	sequence-specific DNA binding	Molecular function	22915762
SASH3	54440	SAM and SH3 domain containing 3	positive regulation of interferon-gamma production	Biological process	-
AAAS	8086	achalasia, adrenocortical insufficiency, alacrimia	molecular_function	Molecular function	-
STRAP	11171	serine/threonine kinase receptor associated protein	plasma membrane	Cellular component	-
CNST	163882	consortin, connexin sorting protein	protein binding	Molecular function	19389623
HNRNPH1	3187	heterogeneous nuclear ribonucleoprotein H1 (H)	catalytic step 2 spliceosome	Cellular component	11991638
C14orf159	80017	chromosome 14 open reading frame 159	biological_process	Biological process	-
KCNJ1	3758	potassium channel, inwardly rectifying subfamily J, member 1	regulation of G-protein activated inward rectifier potassium channel activity	Biological process	-
STEAP1	26872	six transmembrane epithelial antigen of the prostate 1	channel activity	Molecular function	10588738
CORO1B	57175	coronin, actin binding protein, 1B	identical protein binding	Molecular function	16027158
CBR3	874	carbonyl reductase 3	oxidation-reduction process	Biological process	-
TAPBP	6892	TAP binding protein (tapasin)	immune response	Biological process	9271576
TBC1D10B	26000	TBC1 domain family, member 10B	positive regulation of GTPase activity	Biological process	-
PAFAH1B3	5050	platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)	spermatogenesis	Biological process	-
GCNT2	2651	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)	transforming growth factor beta receptor signaling pathway	Biological process	-
PDPN	10630	podoplanin	signal transduction	Biological process	-
IGHV2-70	28454	immunoglobulin heavy variable 2-70	immune response	Biological process	5449120
RHOB	388	ras homolog family member B	cellular response to hydrogen peroxide	Biological process	21373644
MMP13	4322	matrix metallopeptidase 13	extracellular region	Cellular component	-
CAMTA2	23125	calmodulin binding transcription activator 2	transcription factor binding	Molecular function	16678093
YES1	7525	YES proto-oncogene 1, Src family tyrosine kinase	regulation of vascular permeability	Biological process	19267251
ZNF76	7629	zinc finger protein 76	transcription, DNA-templated	Biological process	-
HSPA8	3312	heat shock 70kDa protein 8	RNA splicing	Biological process	-
PDE10A	10846	phosphodiesterase 10A	regulation of protein kinase A signaling	Biological process	-
PARP9	83666	poly (ADP-ribose) polymerase family, member 9	protein binding	Molecular function	16809771
CNTNAP2	26047	contactin associated protein-like 2	adult behavior	Biological process	18179893
KDM5B	10765	lysine (K)-specific demethylase 5B	protein binding	Molecular function	12657635
IFT122	55764	intraflagellar transport 122	establishment of protein localization to organelle	Biological process	-
FGF20	26281	fibroblast growth factor 20	insulin receptor signaling pathway	Biological process	-
CXCR4	7852	chemokine (C-X-C motif) receptor 4	cell surface	Cellular component	10521508
HTR3A	3359	5-hydroxytryptamine (serotonin) receptor 3A, ionotropic	postsynaptic membrane	Cellular component	-
ROPN1B	152015	rhophilin associated tail protein 1B	cytoplasm	Cellular component	11278869
SNX3	8724	sorting nexin 3	negative regulation of phagocytosis	Biological process	23237080
IQGAP3	128239	IQ motif containing GTPase activating protein 3	cell-cell junction	Cellular component	-
GATA5	140628	GATA binding protein 5	intestinal epithelial cell differentiation	Biological process	9566909
IGFBP2	3485	insulin-like growth factor binding protein 2, 36kDa	response to nutrient	Biological process	-
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	smooth muscle cell differentiation	Biological process	-
MLLT10	8028	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10	nucleoplasm	Cellular component	-
SNTG2	54221	syntrophin, gamma 2	syntrophin complex	Cellular component	10747910
KNDC1	85442	kinase non-catalytic C-lobe domain (KIND) containing 1	Ras guanyl-nucleotide exchange factor activity	Molecular function	-
EMP2	2013	epithelial membrane protein 2	cell proliferation	Biological process	21637765
TBL3	10607	transducin (beta)-like 3	nucleolus	Cellular component	-
PRKCE	5581	protein kinase C, epsilon	regulation of peptidyl-tyrosine phosphorylation	Biological process	-
TGFB2	7042	transforming growth factor, beta 2	extracellular matrix	Cellular component	18049952
KRAS	3845	Kirsten rat sarcoma viral oncogene homolog	GTP binding	Molecular function	-
SLC6A17	388662	solute carrier family 6 (neutral amino acid transporter), member 17	transmembrane transport	Biological process	-
IGF2	3481	insulin-like growth factor 2	protein binding	Molecular function	10611375
CCDC126	90693	coiled-coil domain containing 126	membrane	Cellular component	19946888
ABCF1	23	ATP-binding cassette, sub-family F (GCN20), member 1	poly(A) RNA binding	Molecular function	22658674
GATM	2628	glycine amidinotransferase (L-arginine:glycine amidinotransferase)	tissue regeneration	Biological process	-
CYLC1	1538	cylicin, basic protein of sperm head cytoskeleton 1	acrosomal matrix	Cellular component	8354692
EPB42	2038	erythrocyte membrane protein band 4.2	structural constituent of cytoskeleton	Molecular function	1350227
STON2	85439	stonin 2	clathrin adaptor complex	Cellular component	-
DFNB31	25861	deafness, autosomal recessive 31	photoreceptor connecting cilium	Cellular component	-
GNAS	2778	GNAS complex locus	genetic imprinting	Biological process	-
MB	4151	myoglobin	response to hormone	Biological process	-
ZIC2	7546	Zic family member 2	positive regulation of sequence-specific DNA binding transcription factor activity	Biological process	-
ACVRL1	94	activin A receptor type II-like 1	protein heterooligomerization	Biological process	-
UNG	7374	uracil-DNA glycosylase	base-excision repair, AP site formation	Biological process	-
GAS6	2621	growth arrest-specific 6	post-translational protein modification	Biological process	-
SLC27A1	376497	solute carrier family 27 (fatty acid transporter), member 1	cellular lipid metabolic process	Biological process	-
CALCA	796	calcitonin-related polypeptide alpha	positive regulation of interleukin-8 production	Biological process	16904178
SCG3	29106	secretogranin III	secretory granule lumen	Cellular component	-
TP73	7161	tumor protein p73	negative regulation of neuron differentiation	Biological process	-
TPPP	11076	tubulin polymerization promoting protein	microtubule polymerization	Biological process	-
POU4F1	5457	POU class 4 homeobox 1	neuron projection	Cellular component	-
TLX2	3196	T-cell leukemia homeobox 2	negative regulation of dendrite morphogenesis	Biological process	-
CYP2C19	1557	cytochrome P450, family 2, subfamily C, polypeptide 19	oxidation-reduction process	Biological process	16401082
PHF2	5253	PHD finger protein 2	dioxygenase activity	Molecular function	-
BCAM	4059	basal cell adhesion molecule (Lutheran blood group)	transmembrane signaling receptor activity	Molecular function	7777537
CRHBP	1393	corticotropin releasing hormone binding protein	negative regulation of corticotropin secretion	Biological process	1846945
ZBTB6	10773	zinc finger and BTB domain containing 6	protein binding	Molecular function	25416956
FAM213B	127281	family with sequence similarity 213, member B	small molecule metabolic process	Biological process	-
PGA4	643847	pepsinogen 4, group I (pepsinogen A)	protein catabolic process	Biological process	-
PDX1	3651	pancreatic and duodenal homeobox 1	organ morphogenesis	Biological process	8988180
BLOC1S2	282991	biogenesis of lysosomal organelles complex-1, subunit 2	melanosome organization	Biological process	15102850
CREB1	1385	cAMP responsive element binding protein 1	TRIF-dependent toll-like receptor signaling pathway	Biological process	-
PCDH15	65217	protocadherin-related 15	plasma membrane	Cellular component	-
CXCL8	3576	chemokine (C-X-C motif) ligand 8	PERK-mediated unfolded protein response	Biological process	-
PHLPP2	23035	PH domain and leucine rich repeat protein phosphatase 2	fibroblast growth factor receptor signaling pathway	Biological process	-
SRSF6	6431	serine/arginine-rich splicing factor 6	negative regulation of mRNA splicing, via spliceosome	Biological process	15009664
POU2F1	5451	POU class 2 homeobox 1	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
SP3	6670	Sp3 transcription factor	enucleate erythrocyte differentiation	Biological process	-
CD46	4179	CD46 molecule, complement regulatory protein	positive regulation of memory T cell differentiation	Biological process	12540904
NUBPL	80224	nucleotide binding protein-like	4 iron, 4 sulfur cluster binding	Molecular function	19752196
FOXP3	50943	forkhead box P3	positive regulation of immature T cell proliferation in thymus	Biological process	-
RAD51B	5890	RAD51 paralog B	nucleoplasm	Cellular component	-
WDHD1	11169	WD repeat and HMG-box DNA binding protein 1	RNA processing	Biological process	-
CXCR3	2833	chemokine (C-X-C motif) receptor 3	receptor activity	Molecular function	12782716
HIST2H2BD	337874	histone cluster 2, H2bd (pseudogene)	nucleosome	Cellular component	-
STARD3	10948	StAR-related lipid transfer (START) domain containing 3	lipid metabolic process	Biological process	7490069
VDAC2	7417	voltage-dependent anion channel 2	porin activity	Molecular function	-
AGT	183	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	ovarian follicle rupture	Biological process	-
PSTPIP1	9051	proline-serine-threonine phosphatase interacting protein 1	signal transduction	Biological process	9857189
KIF18A	81930	kinesin family member 18A	mitotic sister chromatid segregation	Biological process	-
ALOX15	246	arachidonate 15-lipoxygenase	extrinsic component of cytoplasmic side of plasma membrane	Cellular component	17052953
TRIM23	373	tripartite motif containing 23	ligase activity	Molecular function	-
CDHR5	53841	cadherin-related family member 5	protein binding	Molecular function	24725409
TNFSF11	8600	tumor necrosis factor (ligand) superfamily, member 11	organ morphogenesis	Biological process	-
GLDC	2731	glycine dehydrogenase (decarboxylating)	pyridoxal phosphate binding	Molecular function	-
CEP83	51134	centrosomal protein 83kDa	organelle organization	Biological process	-
CATSPER4	378807	cation channel, sperm associated 4	sperm capacitation	Biological process	-
SLC23A1	9963	solute carrier family 23 (ascorbic acid transporter), member 1	membrane	Cellular component	9804989
RAB10	10890	RAB10, member RAS oncogene family	basolateral protein localization	Biological process	-
OR10Z1	128368	olfactory receptor, family 10, subfamily Z, member 1	plasma membrane	Cellular component	-
IRS1	3667	insulin receptor substrate 1	plasma membrane	Cellular component	-
AGPAT6	137964	1-acylglycerol-3-phosphate O-acyltransferase 6	lipid biosynthetic process	Biological process	-
DHX9	1660	DEAH (Asp-Glu-Ala-His) box helicase 9	positive regulation of type I interferon production	Biological process	-
ALKBH3	221120	alkB, alkylation repair homolog 3 (E. coli)	nucleus	Cellular component	-
PDE10A	10846	phosphodiesterase 10A	regulation of cAMP-mediated signaling	Biological process	-
ELF5	2001	E74-like factor 5 (ets domain transcription factor)	regulation of transcription from RNA polymerase II promoter	Biological process	-
CERS2	29956	ceramide synthase 2	DNA binding	Molecular function	-
KCNA3	3738	potassium channel, voltage gated shaker related subfamily A, member 3	plasma membrane	Cellular component	-
NOL3	8996	nucleolar protein 3 (apoptosis repressor with CARD domain)	RNA splicing	Biological process	10196175
GFRA1	2674	GDNF family receptor alpha 1	glial cell-derived neurotrophic factor receptor activity	Molecular function	10829012
NT5C3A	51251	5'-nucleotidase, cytosolic IIIA	5'-nucleotidase activity	Molecular function	12930399
CHMP2B	25978	charged multivesicular body protein 2B	regulation of mitotic spindle assembly	Biological process	20616062
COL4A5	1287	collagen, type IV, alpha 5	extracellular matrix structural constituent	Molecular function	-
IFNA5	3442	interferon, alpha 5	cytokine receptor binding	Molecular function	6163083
SRGAP1	57522	SLIT-ROBO Rho GTPase activating protein 1	protein binding	Molecular function	17500595
TGFBRAP1	9392	transforming growth factor, beta receptor associated protein 1	regulation of transcription, DNA-templated	Biological process	11278302
PXK	54899	PX domain containing serine/threonine kinase	protein kinase activity	Molecular function	16142408
THBS3	7059	thrombospondin 3	ossification involved in bone maturation	Biological process	-
SATB2	23314	SATB homeobox 2	chromatin remodeling	Biological process	-
FAM9A	171482	family with sequence similarity 9, member A	spermatid development	Biological process	-
SHROOM2	357	shroom family member 2	camera-type eye morphogenesis	Biological process	-
SNAI2	6591	snail family zinc finger 2	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	Biological process	10518215
CCNH	902	cyclin H	transcription initiation from RNA polymerase II promoter	Biological process	-
DLG1	1739	discs, large homolog 1 (Drosophila)	establishment or maintenance of cell polarity	Biological process	12766944
GNAI3	2773	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3	vesicle fusion	Biological process	-
TDRD7	23424	tudor domain containing 7	spermatogenesis	Biological process	-
ADAM10	102	ADAM metallopeptidase domain 10	intracellular membrane-bounded organelle	Cellular component	-
CRTAP	10491	cartilage associated protein	extracellular space	Cellular component	19846465
PEX2	5828	peroxisomal biogenesis factor 2	negative regulation of epithelial cell proliferation	Biological process	18987311
AIM2	9447	absent in melanoma 2	cellular response to drug	Biological process	19158679
CPSF1	29894	cleavage and polyadenylation specific factor 1, 160kDa	termination of RNA polymerase II transcription	Biological process	-
LRP2	4036	low density lipoprotein receptor-related protein 2	small molecule metabolic process	Biological process	-
SPHK2	56848	sphingosine kinase 2	sphingolipid biosynthetic process	Biological process	-
SLMAP	7871	sarcolemma associated protein	muscle contraction	Biological process	-
BMP2	650	bone morphogenetic protein 2	protein phosphorylation	Biological process	22540193
HACD4	401494	3-hydroxyacyl-CoA dehydratase 4	integral component of membrane	Cellular component	-
TCHP	84260	trichoplein, keratin filament binding	apoptotic process	Biological process	18931701
CALCA	796	calcitonin-related polypeptide alpha	positive regulation of cytosolic calcium ion concentration	Biological process	17983652
MMP13	4322	matrix metallopeptidase 13	bone mineralization	Biological process	-
ZXDC	79364	ZXD family zinc finger C	transcription, DNA-templated	Biological process	-
WASL	8976	Wiskott-Aldrich syndrome-like	Fc-gamma receptor signaling pathway involved in phagocytosis	Biological process	-
MPP5	64398	membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)	protein domain specific binding	Molecular function	17332497
OR8D4	338662	olfactory receptor, family 8, subfamily D, member 4	G-protein coupled receptor signaling pathway	Biological process	-
TLR7	51284	toll-like receptor 7	endosome membrane	Cellular component	-
MSH2	4436	mutS homolog 2	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	Biological process	-
PTHLH	5744	parathyroid hormone-like hormone	extracellular region	Cellular component	-
DHX34	9704	DEAH (Asp-Glu-Ala-His) box polypeptide 34	RNA processing	Biological process	-
ZCCHC17	51538	zinc finger, CCHC domain containing 17	poly(A) RNA binding	Molecular function	22658674
SPTBN5	51332	spectrin, beta, non-erythrocytic 5	kinesin binding	Molecular function	23704327
PTGIS	5740	prostaglandin I2 (prostacyclin) synthase	iron ion binding	Molecular function	-
GCGR	2642	glucagon receptor	generation of precursor metabolites and energy	Biological process	7773293
CACNA1H	8912	calcium channel, voltage-dependent, T type, alpha 1H subunit	cortisol biosynthetic process	Biological process	19342457
KLF1	10661	Kruppel-like factor 1 (erythroid)	erythrocyte maturation	Biological process	-
BBS7	55212	Bardet-Biedl syndrome 7	ciliary basal body	Cellular component	-
PTPN2	5771	protein tyrosine phosphatase, non-receptor type 2	negative regulation of tyrosine phosphorylation of Stat6 protein	Biological process	17210636
ZMIZ1	57178	zinc finger, MIZ-type containing 1	cell aging	Biological process	-
CHD8	57680	chromodomain helicase DNA binding protein 8	DNA-dependent ATPase activity	Molecular function	18378692
EEF1A1	1915	eukaryotic translation elongation factor 1 alpha 1	regulation of transcription, DNA-templated	Biological process	-
POU2F1	5451	POU class 2 homeobox 1	transcription factor complex	Cellular component	-
TNXB	7148	tenascin XB	elastic fiber assembly	Biological process	15102077
IL1RN	3557	interleukin 1 receptor antagonist	carboxylic acid metabolic process	Biological process	-
MGRN1	23295	mahogunin ring finger 1, E3 ubiquitin protein ligase	endosome to lysosome transport	Biological process	17229889
EXOC8	149371	exocyst complex component 8	protein binding	Molecular function	16189514
NOL6	65083	nucleolar protein 6 (RNA-associated)	condensed nuclear chromosome	Cellular component	11895476
RPP38	10557	ribonuclease P/MRP 38kDa subunit	nucleolar ribonuclease P complex	Cellular component	9630247
GUK1	2987	guanylate kinase 1	GDP-mannose metabolic process	Biological process	-
ACER2	340485	alkaline ceramidase 2	Golgi apparatus	Cellular component	16940153
ZFR	51663	zinc finger RNA binding protein	zinc ion binding	Molecular function	-
PLA2G4B	100137049	phospholipase A2, group IVB (cytosolic)	mitochondrial inner membrane	Cellular component	-
DCTD	1635	dCMP deaminase	nucleotide biosynthetic process	Biological process	-
IYD	389434	iodotyrosine deiodinase	protein binding	Molecular function	25416956
DIAPH3	81624	diaphanous-related formin 3	actin cytoskeleton organization	Biological process	-
NKG7	4818	natural killer cell granule protein 7	protein binding	Molecular function	25416956
CAMK4	814	calcium/calmodulin-dependent protein kinase IV	positive regulation of transcription, DNA-templated	Biological process	8855261
RPS4Y1	6192	ribosomal protein S4, Y-linked 1	polysome	Cellular component	8139551
TPR	7175	translocated promoter region, nuclear basket protein	viral life cycle	Biological process	-
CHAF1B	8208	chromatin assembly factor 1, subunit B (p60)	protein complex	Cellular component	14718166
LRRK1	79705	leucine-rich repeat kinase 1	ATP binding	Molecular function	-
TAAR1	134864	trace amine associated receptor 1	plasma membrane	Cellular component	-
TAF1B	9014	TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa	transcription elongation from RNA polymerase I promoter	Biological process	-
VN1R3	317702	vomeronasal 1 receptor 3 (gene/pseudogene)	plasma membrane	Cellular component	-
SUDS3	64426	suppressor of defective silencing 3 homolog (S. cerevisiae)	positive regulation of apoptotic process	Biological process	21239494
MBOAT7	79143	membrane bound O-acyltransferase domain containing 7	phosphatidylinositol acyl-chain remodeling	Biological process	-
IL12A	3592	interleukin 12A	protein heterodimerization activity	Molecular function	11023671
STOML3	161003	stomatin (EPB72)-like 3	cilium	Cellular component	-
RGS9	8787	regulator of G-protein signaling 9	cytoplasm	Cellular component	-
CTH	1491	cystathionine gamma-lyase	pyridoxal phosphate binding	Molecular function	10212249
ITSN2	50618	intersectin 2	extracellular exosome	Cellular component	19056867
DTHD1	401124	death domain containing 1	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
CDKN1B	1027	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	negative regulation of apoptotic process	Biological process	-
ARMC10	83787	armadillo repeat containing 10	integral component of membrane	Cellular component	-
DNASE1L3	1776	deoxyribonuclease I-like 3	nucleus	Cellular component	-
DVL2	1856	dishevelled segment polarity protein 2	neural tube closure	Biological process	-
MUC1	4582	mucin 1, cell surface associated	positive regulation of histone H4 acetylation	Biological process	15710329
VANGL2	57216	VANGL planar cell polarity protein 2	hair follicle development	Biological process	-
SMARCC2	6601	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	RNA polymerase II distal enhancer sequence-specific DNA binding	Molecular function	16217013
AKR1B10	57016	aldo-keto reductase family 1, member B10 (aldose reductase)	protein binding	Molecular function	18056116
TMEM243	79161	transmembrane protein 243, mitochondrial	integral component of membrane	Cellular component	-
HINT1	3094	histidine triad nucleotide binding protein 1	plasma membrane	Cellular component	-
POLA2	23649	polymerase (DNA directed), alpha 2, accessory subunit	alpha DNA polymerase:primase complex	Cellular component	-
PLXNA1	5361	plexin A1	axon guidance	Biological process	-
THY1	7070	Thy-1 cell surface antigen	negative regulation of protein kinase activity	Biological process	-
DHX36	170506	DEAH (Asp-Glu-Ala-His) box polypeptide 36	cytosol	Cellular component	-
RARA	5914	retinoic acid receptor, alpha	transcription initiation from RNA polymerase II promoter	Biological process	-
EARS2	124454	glutamyl-tRNA synthetase 2, mitochondrial	mitochondrial matrix	Cellular component	-
MAPK1	5594	mitogen-activated protein kinase 1	signal transduction	Biological process	1540184
APOA2	336	apolipoprotein A-II	phospholipid catabolic process	Biological process	14967812
TMEM30A	55754	transmembrane protein 30A	positive regulation of protein exit from endoplasmic reticulum	Biological process	21914794
IHH	3549	indian hedgehog	negative regulation of signal transduction	Biological process	-
GRIK1	2897	glutamate receptor, ionotropic, kainate 1	positive regulation of gamma-aminobutyric acid secretion	Biological process	-
DBT	1629	dihydrolipoamide branched chain transacylase E2	mitochondrial alpha-ketoglutarate dehydrogenase complex	Cellular component	1429740
PTPN23	25930	protein tyrosine phosphatase, non-receptor type 23	protein transport	Biological process	-
KCNK2	3776	potassium channel, two pore domain subfamily K, member 2	stabilization of membrane potential	Biological process	-
GALNT2	2590	polypeptide N-acetylgalactosaminyltransferase 2	Golgi cisterna membrane	Cellular component	-
MAP3K3	4215	mitogen-activated protein kinase kinase kinase 3	positive regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	12761501
PRDM12	59335	PR domain containing 12	sequence-specific DNA binding RNA polymerase II transcription factor activity	Molecular function	-
MAPK1	5594	mitogen-activated protein kinase 1	ERBB signaling pathway	Biological process	15133037
GNAT1	2779	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1	photoreceptor outer segment membrane	Cellular component	-
CALCRL	10203	calcitonin receptor-like	adrenomedullin receptor activity	Molecular function	22102369
RIPPLY2	134701	ripply transcriptional repressor 2	somite rostral/caudal axis specification	Biological process	-
RPL4	6124	ribosomal protein L4	cellular protein metabolic process	Biological process	-
OLAH	55301	oleoyl-ACP hydrolase	palmitoyl-[acyl-carrier-protein] hydrolase activity	Molecular function	-
RPL23A	6147	ribosomal protein L23a	TORC2 complex	Cellular component	-
RPA1	6117	replication protein A1, 70kDa	damaged DNA binding	Molecular function	7700386
CTSZ	1522	cathepsin Z	lysosome	Cellular component	-
PPP1R9A	55607	protein phosphatase 1, regulatory subunit 9A	dendritic spine	Cellular component	-
ATP1A1	476	ATPase, Na+/K+ transporting, alpha 1 polypeptide	endoplasmic reticulum	Cellular component	-
SYT13	57586	synaptotagmin XIII	calcium ion binding	Molecular function	-
FAM215A	23591	family with sequence similarity 215, member A (non-protein coding)	biological_process	Biological process	-
RPS5	6193	ribosomal protein S5	viral process	Biological process	-
GAL	51083	galanin/GMAP prepropeptide	Golgi apparatus	Cellular component	-
MCM8	84515	minichromosome maintenance complex component 8	DNA strand elongation involved in DNA replication	Biological process	-
CYBB	1536	cytochrome b-245, beta polypeptide	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	Biological process	-
INSR	3643	insulin receptor	extracellular exosome	Cellular component	20458337
ARG1	383	arginase 1	response to amino acid	Biological process	-
KIF3B	9371	kinesin family member 3B	mitotic spindle assembly	Biological process	19635168
KCNK3	3777	potassium channel, two pore domain subfamily K, member 3	activation of mitophagy in response to mitochondrial depolarization	Biological process	22020285
KCNH1	3756	potassium channel, voltage gated eag related subfamily H, member 1	synaptic transmission	Biological process	-
PVRL4	81607	poliovirus receptor-related 4	plasma membrane	Cellular component	-
SWI5	375757	SWI5 recombination repair homolog (yeast)	double-strand break repair via homologous recombination	Biological process	21252223
TMEM181	57583	transmembrane protein 181	pathogenesis	Biological process	19965467
IGF1	3479	insulin-like growth factor 1 (somatomedin C)	positive regulation of phosphatidylinositol 3-kinase signaling	Biological process	7688386
ADAM21	8747	ADAM metallopeptidase domain 21	axon	Cellular component	-
SMTNL1	219537	smoothelin-like 1	positive regulation of vasoconstriction	Biological process	-
MGAT4C	25834	MGAT4 family, member C	post-translational protein modification	Biological process	-
IGHG3	3502	immunoglobulin heavy constant gamma 3 (G3m marker)	antigen binding	Molecular function	-
UTP11L	51118	UTP11-like, U3 small nucleolar ribonucleoprotein (yeast)	extracellular space	Cellular component	11860508
ROCK1	6093	Rho-associated, coiled-coil containing protein kinase 1	negative regulation of angiogenesis	Biological process	19181962
PRKDC	5591	protein kinase, DNA-activated, catalytic polypeptide	ectopic germ cell programmed cell death	Biological process	-
HMGCS2	3158	3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)	ketone body biosynthetic process	Biological process	-
PKP3	11187	plakophilin 3	establishment of protein localization to plasma membrane	Biological process	20859650
HDAC5	10014	histone deacetylase 5	Notch signaling pathway	Biological process	-
OFD1	8481	oral-facial-digital syndrome 1	alpha-tubulin binding	Molecular function	-
VPS33A	65082	vacuolar protein sorting 33 homolog A (S. cerevisiae)	platelet formation	Biological process	-
MKL1	57591	megakaryoblastic leukemia (translocation) 1	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	-
SMARCA4	6597	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	nucleoplasm	Cellular component	-
TYK2	7297	tyrosine kinase 2	cell differentiation	Biological process	-
BCHE	590	butyrylcholinesterase	endoplasmic reticulum lumen	Cellular component	-
HERPUD1	9709	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	negative regulation of intrinsic apoptotic signaling pathway	Biological process	22045699
RPL18A	6142	ribosomal protein L18a	translational termination	Biological process	-
CREB3L3	84699	cAMP responsive element binding protein 3-like 3	protein binding	Molecular function	16469704
PRRT1	80863	proline-rich transmembrane protein 1	response to biotic stimulus	Biological process	-
DAPK1	1612	death-associated protein kinase 1	negative regulation of translation	Biological process	18995835
CD40	958	CD40 molecule, TNF receptor superfamily member 5	external side of plasma membrane	Cellular component	-
MUC19	283463	mucin 19, oligomeric	post-translational protein modification	Biological process	-
HRG	3273	histidine-rich glycoprotein	negative regulation of cell adhesion	Biological process	14744774
TEX14	56155	testis expressed 14	protein kinase binding	Molecular function	22405274
SGPL1	8879	sphingosine-1-phosphate lyase 1	sphingolipid biosynthetic process	Biological process	-
PKD2L1	9033	polycystic kidney disease 2-like 1	cytoskeletal protein binding	Molecular function	12809519
MR1	3140	major histocompatibility complex, class I-related	integral component of membrane	Cellular component	-
DDX3Y	8653	DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked	cytoplasmic ribonucleoprotein granule	Cellular component	-
TRH	7200	thyrotropin-releasing hormone	plasma membrane	Cellular component	-
SLC11A1	6556	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1	vacuolar acidification	Biological process	-
C19orf57	79173	chromosome 19 open reading frame 57	multicellular organismal development	Biological process	8228263
ATG12	9140	autophagy related 12	negative regulation of type I interferon production	Biological process	-
CCR8	1237	chemokine (C-C motif) receptor 8	positive regulation of cytosolic calcium ion concentration	Biological process	-
REXO2	25996	RNA exonuclease 2	mitochondrial intermembrane space	Cellular component	-
TRAPPC4	51399	trafficking protein particle complex 4	dendrite	Cellular component	11018053
FBN1	2200	fibrillin 1	sequestering of TGFbeta in extracellular matrix	Biological process	-
CDKN2C	1031	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	negative regulation of cell growth	Biological process	10208428
CKAP4	10970	cytoskeleton-associated protein 4	plasma membrane	Cellular component	-
ZNF354A	6940	zinc finger protein 354A	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
FGF1	2246	fibroblast growth factor 1 (acidic)	branch elongation involved in ureteric bud branching	Biological process	11731227
RBM4	5936	RNA binding motif protein 4	cell differentiation	Biological process	-
PCDHA7	56141	protocadherin alpha 7	integral component of plasma membrane	Cellular component	10380929
TYW5	129450	tRNA-yW synthesizing protein 5	wybutosine biosynthetic process	Biological process	20739293
PREB	10113	prolactin regulatory element binding	protein transport	Biological process	-
PTX3	5806	pentraxin 3, long	opsonization	Biological process	-
PTEN	5728	phosphatase and tensin homolog	inositol phosphate metabolic process	Biological process	-
PDHA2	5161	pyruvate dehydrogenase (lipoamide) alpha 2	glucose metabolic process	Biological process	-
AKR1C3	8644	aldo-keto reductase family 1, member C3	progesterone metabolic process	Biological process	21232532
RPL13AP3	645683	ribosomal protein L13a pseudogene 3	structural constituent of ribosome	Molecular function	-
TRPC1	7220	transient receptor potential cation channel, subfamily C, member 1	melanin biosynthetic process	Biological process	8126111
HDAC5	10014	histone deacetylase 5	cellular response to insulin stimulus	Biological process	18184930
RHOA	387	ras homolog family member A	focal adhesion	Cellular component	21423176
HSD17B11	51170	hydroxysteroid (17-beta) dehydrogenase 11	lipid particle	Cellular component	14741744
STIP1	10963	stress-induced phosphoprotein 1	poly(A) RNA binding	Molecular function	22658674
REN	5972	renin	cellular response to drug	Biological process	-
HEBP2	23593	heme binding protein 2	regulation of response to reactive oxygen species	Biological process	17098234
HOXB1	3211	homeobox B1	protein domain specific binding	Molecular function	10052460
PPARD	5467	peroxisome proliferator-activated receptor delta	cell-substrate adhesion	Biological process	-
CD24	100133941	CD24 molecule	protein binding	Molecular function	15633604
OR4D6	219983	olfactory receptor, family 4, subfamily D, member 6	integral component of membrane	Cellular component	-
OR2J1	442185	olfactory receptor, family 2, subfamily J, member 1 (gene/pseudogene)	olfactory receptor activity	Molecular function	-
CD63	967	CD63 molecule	protein transport	Biological process	-
B3GNT5	84002	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5	protein glycosylation	Biological process	11384981
YWHAH	7533	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta	cytoplasm	Cellular component	-
APOH	350	apolipoprotein H (beta-2-glycoprotein I)	lipid binding	Molecular function	222615
UGT2A1	10941	UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus	sensory perception of smell	Biological process	-
LSM7	51690	LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)	small nucleolar ribonucleoprotein complex	Cellular component	-
CDKN1B	1027	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	response to peptide hormone	Biological process	-
GPATCH8	23131	G patch domain containing 8	biological_process	Biological process	-
CAMTA2	23125	calmodulin binding transcription activator 2	regulation of transcription from RNA polymerase II promoter	Biological process	16678093
ADM	133	adrenomedullin	neuron projection regeneration	Biological process	-
WFS1	7466	Wolfram syndrome 1 (wolframin)	kidney development	Biological process	9817917
CDC27	996	cell division cycle 27	mitotic spindle assembly checkpoint	Biological process	-
TMEM27	57393	transmembrane protein 27	proteolysis	Biological process	-
SLC22A3	6581	solute carrier family 22 (organic cation transporter), member 3	toxin transport	Biological process	-
VCP	7415	valosin containing protein	identical protein binding	Molecular function	-
FGF10	2255	fibroblast growth factor 10	actin cytoskeleton reorganization	Biological process	17449030
IKZF4	64375	IKAROS family zinc finger 4 (Eos)	sequence-specific DNA binding transcription factor activity	Molecular function	10978333
PCSK2	5126	proprotein convertase subtilisin/kexin type 2	secretory granule lumen	Cellular component	-
FGF9	2254	fibroblast growth factor 9	negative regulation of Wnt signaling pathway	Biological process	-
FKBP1B	2281	FK506 binding protein 1B, 12.6 kDa	response to redox state	Biological process	19226252
ENTPD5	957	ectonucleoside triphosphate diphosphohydrolase 5	regulation of phosphatidylinositol 3-kinase signaling	Biological process	-
WARS	7453	tryptophanyl-tRNA synthetase	translation	Biological process	1761529
ABCG1	9619	ATP-binding cassette, sub-family G (WHITE), member 1	lipoprotein metabolic process	Biological process	-
TRPV2	51393	transient receptor potential cation channel, subfamily V, member 2	ion channel activity	Molecular function	10201375
TAF1D	79101	TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa	transcription from RNA polymerase I promoter	Biological process	-
CCNY	219771	cyclin Y	plasma membrane	Cellular component	19524571
EIF2B1	1967	eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa	response to heat	Biological process	12499492
PIGL	9487	phosphatidylinositol glycan anchor biosynthesis, class L	integral component of membrane	Cellular component	-
HLA-DRA	3122	major histocompatibility complex, class II, DR alpha	endocytic vesicle membrane	Cellular component	-
MAPK11	5600	mitogen-activated protein kinase 11	nucleoplasm	Cellular component	-
PRLR	5618	prolactin receptor	steroid biosynthetic process	Biological process	10585417
HOXA4	3201	homeobox A4	sequence-specific DNA binding	Molecular function	-
DGKB	1607	diacylglycerol kinase, beta 90kDa	cytoplasm	Cellular component	-
CEP72	55722	centrosomal protein 72kDa	centrosome	Cellular component	19536135
RAB14	51552	RAB14, member RAS oncogene family	fibroblast growth factor receptor signaling pathway	Biological process	-
MND1	84057	meiotic nuclear divisions 1 homolog (S. cerevisiae)	meiotic cell cycle	Biological process	-
NAA15	80155	N(alpha)-acetyltransferase 15, NatA auxiliary subunit	negative regulation of apoptotic process	Biological process	19480662
CSK	1445	c-src tyrosine kinase	protein phosphorylation	Biological process	1945408
SHISA8	440829	shisa family member 8	integral component of membrane	Cellular component	-
TBRG1	84897	transforming growth factor beta regulator 1	cell cycle arrest	Biological process	17110379
FOXO1	2308	forkhead box O1	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
SDHA	6389	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	succinate dehydrogenase activity	Molecular function	7550341
TMEM107	84314	transmembrane protein 107	integral component of membrane	Cellular component	-
HOXD10	3236	homeobox D10	skeletal muscle tissue development	Biological process	-
NOS1AP	9722	nitric oxide synthase 1 (neuronal) adaptor protein	regulation of ventricular cardiac muscle cell membrane repolarization	Biological process	18337493
CSF1R	1436	colony stimulating factor 1 receptor	positive regulation of protein tyrosine kinase activity	Biological process	7681396
RPAP1	26015	RNA polymerase II associated protein 1	DNA binding	Molecular function	-
GJA5	2702	gap junction protein, alpha 5, 40kDa	positive regulation of vasodilation	Biological process	-
CSK	1445	c-src tyrosine kinase	cell-cell junction	Cellular component	-
EPO	2056	erythropoietin	cellular hyperosmotic response	Biological process	14569084
TESK2	10420	testis-specific kinase 2	actin cytoskeleton organization	Biological process	-
GATA1	2623	GATA binding protein 1 (globin transcription factor 1)	eosinophil fate commitment	Biological process	12045236
PDGFA	5154	platelet-derived growth factor alpha polypeptide	Fc-epsilon receptor signaling pathway	Biological process	-
UBA5	79876	ubiquitin-like modifier activating enzyme 5	protein ufmylation	Biological process	23152784
GRID1	2894	glutamate receptor, ionotropic, delta 1	cell junction	Cellular component	-
CLPX	10845	caseinolytic mitochondrial matrix peptidase chaperone subunit	peptidase activator activity	Molecular function	11923310
NR2E3	10002	nuclear receptor subfamily 2, group E, member 3	steroid hormone receptor activity	Molecular function	-
NIF3L1	60491	NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)	cytoplasm	Cellular component	12951069
PTPRD	5789	protein tyrosine phosphatase, receptor type, D	extracellular exosome	Cellular component	23533145
ITGB3	3690	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	extracellular exosome	Cellular component	20458337
GREM1	26585	gremlin 1, DAN family BMP antagonist	negative regulation of bone mineralization involved in bone maturation	Biological process	15539560
B4GALNT3	283358	beta-1,4-N-acetyl-galactosaminyl transferase 3	acetylgalactosaminyltransferase activity	Molecular function	12966086
CADPS	8618	Ca++-dependent secretion activator	cytosol	Cellular component	1516133
SCGB1A1	7356	secretoglobin, family 1A, member 1 (uteroglobin)	response to drug	Biological process	-
ADSL	158	adenylosuccinate lyase	small molecule metabolic process	Biological process	-
PARK2	5071	parkin RBR E3 ubiquitin protein ligase	regulation of reactive oxygen species metabolic process	Biological process	18541373
HIST1H4I	8294	histone cluster 1, H4i	DNA binding	Molecular function	3035717
PHOX2B	8929	paired-like homeobox 2b	sympathetic ganglion development	Biological process	-
POLR2D	5433	polymerase (RNA) II (DNA directed) polypeptide D	somatic stem cell maintenance	Biological process	-
MLF1	4291	myeloid leukemia factor 1	protein domain specific binding	Molecular function	12176995
SERPINF2	5345	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2	collagen fibril organization	Biological process	17958745
F3	2152	coagulation factor III (thromboplastin, tissue factor)	activation of blood coagulation via clotting cascade	Biological process	17469850
PTPN6	5777	protein tyrosine phosphatase, non-receptor type 6	blood coagulation	Biological process	-
SALL1	6299	spalt-like transcription factor 1	olfactory bulb interneuron differentiation	Biological process	-
APC2	10297	adenomatosis polyposis coli 2	cytoplasm	Cellular component	11691822
MYO1G	64005	myosin IG	microvillus	Cellular component	-
AUP1	550	ancient ubiquitous protein 1	endoplasmic reticulum membrane	Cellular component	-
NXF2	56001	nuclear RNA export factor 2	nuclear RNA export factor complex	Cellular component	11073998
IFNE	338376	interferon, epsilon	defense response to bacterium	Biological process	-
MAEL	84944	maelstrom spermatogenic transposon silencer	fertilization	Biological process	-
IRAK1	3654	interleukin-1 receptor-associated kinase 1	toll-like receptor TLR6:TLR2 signaling pathway	Biological process	-
ZCCHC17	51538	zinc finger, CCHC domain containing 17	ribonucleoprotein complex	Cellular component	-
SH2D1A	4068	SH2 domain containing 1A	SH3/SH2 adaptor activity	Molecular function	9774102
CLK4	57396	CDC-like kinase 4	protein serine/threonine/tyrosine kinase activity	Molecular function	-
HAUS6	54801	HAUS augmin-like complex, subunit 6	cytoplasm	Cellular component	-
RPA3	6119	replication protein A3, 14kDa	DNA replication	Biological process	-
CDH15	1013	cadherin 15, type 1, M-cadherin (myotubule)	calcium ion binding	Molecular function	-
NOTCH1	4851	notch 1	negative regulation of ossification	Biological process	-
VAV1	7409	vav 1 guanine nucleotide exchange factor	small GTPase mediated signal transduction	Biological process	-
SRSF4	6429	serine/arginine-rich splicing factor 4	gene expression	Biological process	-
PLA2G4D	283748	phospholipase A2, group IVD (cytosolic)	glycerophospholipid biosynthetic process	Biological process	-
TP53	7157	tumor protein p53	regulation of intrinsic apoptotic signaling pathway by p53 class mediator	Biological process	-
HDAC3	8841	histone deacetylase 3	NAD-dependent histone deacetylase activity (H3-K18 specific)	Molecular function	-
WIBG	84305	within bgcn homolog (Drosophila)	ribosome binding	Molecular function	18026120
ACVR2B	93	activin A receptor, type IIB	insulin secretion	Biological process	-
RTEL1	51750	regulator of telomere elongation helicase 1	ATP binding	Molecular function	18957201
ZP3	7784	zona pellucida glycoprotein 3 (sperm receptor)	outer acrosomal membrane	Cellular component	-
CPEB2	132864	cytoplasmic polyadenylation element binding protein 2	cellular response to insulin stimulus	Biological process	18752464
AGBL4	84871	ATP/GTP binding protein-like 4	cytosol	Cellular component	-
RIPK2	8767	receptor-interacting serine-threonine kinase 2	toll-like receptor TLR6:TLR2 signaling pathway	Biological process	-
SLC35D1	23169	solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1	small molecule metabolic process	Biological process	-
ARMC10	83787	armadillo repeat containing 10	regulation of growth	Biological process	-
ATXN3	4287	ataxin 3	cellular response to misfolded protein	Biological process	-
RSL24D1	51187	ribosomal L24 domain containing 1	nucleus	Cellular component	-
RFC3	5983	replication factor C (activator 1) 3, 38kDa	DNA damage response, detection of DNA damage	Biological process	-
RAC1	5879	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	positive regulation of DNA replication	Biological process	-
TNNT3	7140	troponin T type 3 (skeletal, fast)	troponin C binding	Molecular function	8987992
IARS2	55699	isoleucyl-tRNA synthetase 2, mitochondrial	mitochondrial matrix	Cellular component	-
FAM198A	729085	family with sequence similarity 198, member A	extracellular region	Cellular component	-
KCNJ11	3767	potassium channel, inwardly rectifying subfamily J, member 11	G-protein activated inward rectifier potassium channel activity	Molecular function	-
IFI16	3428	interferon, gamma-inducible protein 16	transcription factor binding	Molecular function	12894224
MARK3	4140	MAP/microtubule affinity-regulating kinase 3	protein binding	Molecular function	12556533
KCNMB3	27094	potassium channel subfamily M regulatory beta subunit 3	calcium-activated potassium channel activity	Molecular function	10692449
C8G	733	complement component 8, gamma polypeptide	extracellular region	Cellular component	-
GABRB3	2562	gamma-aminobutyric acid (GABA) A receptor, beta 3	transport	Biological process	1664410
ZNF331	55422	zinc finger protein 331	DNA binding	Molecular function	-
MASP1	5648	mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)	peptidase activity	Molecular function	10946292
FHIT	2272	fragile histidine triad	extracellular exosome	Cellular component	23376485
ACLY	47	ATP citrate lyase	positive regulation of cellular metabolic process	Biological process	-
DHX34	9704	DEAH (Asp-Glu-Ala-His) box polypeptide 34	ATP binding	Molecular function	-
Sep-03	55964	septin 3	synapse	Cellular component	-
TPCN2	219931	two pore segment channel 2	release of sequestered calcium ion into cytosol	Biological process	-
CC2D1A	54862	coiled-coil and C2 domain containing 1A	cytoplasm	Cellular component	-
BIRC5	332	baculoviral IAP repeat containing 5	negative regulation of transcription, DNA-templated	Biological process	20826784
TUBGCP4	27229	tubulin, gamma complex associated protein 4	structural constituent of cytoskeleton	Molecular function	10562286
CAV1	857	caveolin 1, caveolae protein, 22kDa	positive regulation of extrinsic apoptotic signaling pathway	Biological process	21382479
BSG	682	basigin (Ok blood group)	extracellular exosome	Cellular component	20458337
SNX13	23161	sorting nexin 13	positive regulation of GTPase activity	Biological process	11729322
DHX36	170506	DEAH (Asp-Glu-Ala-His) box polypeptide 36	cytoplasm	Cellular component	-
IFT172	26160	intraflagellar transport 172	hindgut development	Biological process	-
SCG3	29106	secretogranin III	platelet activation	Biological process	-
SLC22A4	6583	solute carrier family 22 (organic cation/zwitterion transporter), member 4	body fluid secretion	Biological process	9426230
CXCL3	2921	chemokine (C-X-C motif) ligand 3	chemokine activity	Molecular function	-
ENOX1	55068	ecto-NOX disulfide-thiol exchanger 1	oxidation-reduction process	Biological process	-
SMAD3	4088	SMAD family member 3	cell cycle arrest	Biological process	14555988
PKD2L1	9033	polycystic kidney disease 2-like 1	sodium ion transmembrane transport	Biological process	10517637
NCOR2	9612	nuclear receptor corepressor 2	transforming growth factor beta receptor signaling pathway	Biological process	-
ATF6	22926	activating transcription factor 6	transcription coactivator activity	Molecular function	10866666
KCNJ15	3772	potassium channel, inwardly rectifying subfamily J, member 15	protein binding	Molecular function	9647694
NUDT18	79873	nudix (nucleoside diphosphate linked moiety X)-type motif 18	8-hydroxy-dADP phosphatase activity	Molecular function	22556419
EIF3B	8662	eukaryotic translation initiation factor 3, subunit B	eukaryotic 48S preinitiation complex	Cellular component	-
ZNF746	155061	zinc finger protein 746	transcription, DNA-templated	Biological process	-
CYP2E1	1571	cytochrome P450, family 2, subfamily E, polypeptide 1	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	Molecular function	-
HOXD1	3231	homeobox D1	nucleus	Cellular component	-
TXNDC15	79770	thioredoxin domain containing 15	cell	Cellular component	-
SLC24A1	9187	solute carrier family 24 (sodium/potassium/calcium exchanger), member 1	ion transport	Biological process	-
IL12A	3592	interleukin 12A	positive regulation of smooth muscle cell apoptotic process	Biological process	16942485
P2RX3	5024	purinergic receptor P2X, ligand gated ion channel, 3	response to carbohydrate	Biological process	-
AKAP13	11214	A kinase (PRKA) anchor protein 13	cytoplasm	Cellular component	-
SPP2	6694	secreted phosphoprotein 2, 24kDa	endopeptidase inhibitor activity	Molecular function	7814406
DPPA5	340168	developmental pluripotency associated 5	multicellular organismal development	Biological process	-
CA9	768	carbonic anhydrase IX	cellular response to hypoxia	Biological process	-
ZHX1	11244	zinc fingers and homeoboxes 1	nucleoplasm	Cellular component	-
SGSH	6448	N-sulfoglucosamine sulfohydrolase	carbohydrate metabolic process	Biological process	-
CCSAP	126731	centriole, cilia and spindle-associated protein	spindle	Cellular component	22493317
CHMP3	51652	charged multivesicular body protein 3	protein heterooligomerization	Biological process	18687924
SETBP1	26040	SET binding protein 1	DNA binding	Molecular function	-
RAB3D	9545	RAB3D, member RAS oncogene family	vesicle docking involved in exocytosis	Biological process	-
RECQL4	9401	RecQ protein-like 4	cytoplasm	Cellular component	-
ITGA1	3672	integrin, alpha 1	protein binding	Molecular function	16754661
CCDC88A	55704	coiled-coil domain containing 88A	Golgi apparatus	Cellular component	15882442
CTSS	1520	cathepsin S	lysosomal lumen	Cellular component	-
HBM	3042	hemoglobin, mu	oxygen transporter activity	Molecular function	-
ATP1A3	478	ATPase, Na+/K+ transporting, alpha 3 polypeptide	endoplasmic reticulum	Cellular component	15260953
ACPT	93650	acid phosphatase, testicular	dephosphorylation	Biological process	-
TYRP1	7306	tyrosinase-related protein 1	melanosome membrane	Cellular component	-
LEP	3952	leptin	response to insulin	Biological process	-
STIL	6491	SCL/TAL1 interrupting locus	centrosome duplication	Biological process	22349705
CLIC3	9022	chloride intracellular channel 3	chloride transport	Biological process	9880541
MAGT1	84061	magnesium transporter 1	protein N-linked glycosylation via asparagine	Biological process	-
HDAC6	10013	histone deacetylase 6	polyubiquitinated misfolded protein transport	Biological process	14675537
MLKL	197259	mixed lineage kinase domain-like	programmed necrotic cell death	Biological process	-
NDUFS8	4728	NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)	mitochondrial respiratory chain complex I	Cellular component	9878551
BBIP1	92482	BBSome interacting protein 1	cytoplasm	Cellular component	19081074
ATRAID	51374	all-trans retinoic acid-induced differentiation factor	perinuclear region of cytoplasm	Cellular component	21723284
CCNC	892	cyclin C	nucleoplasm	Cellular component	-
AQP10	89872	aquaporin 10	plasma membrane	Cellular component	-
USP19	10869	ubiquitin specific peptidase 19	ER-associated ubiquitin-dependent protein catabolic process	Biological process	19465887
GBX1	2636	gastrulation brain homeobox 1	transcription, DNA-templated	Biological process	-
RBPJL	11317	recombination signal binding protein for immunoglobulin kappa J region-like	nucleus	Cellular component	-
GNAT1	2779	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1	photoreceptor connecting cilium	Cellular component	-
PAX4	5078	paired box 4	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
IL6	3569	interleukin 6	cellular response to dexamethasone stimulus	Biological process	-
DHCR24	1718	24-dehydrocholesterol reductase	cytoskeleton	Cellular component	-
MYLK4	340156	myosin light chain kinase family, member 4	extracellular exosome	Cellular component	23376485
BBS7	55212	Bardet-Biedl syndrome 7	heart looping	Biological process	-
ADM	133	adrenomedullin	blood circulation	Biological process	8074714
GNB1	2782	guanine nucleotide binding protein (G protein), beta polypeptide 1	extracellular vesicle	Cellular component	24769233
H2AFJ	55766	H2A histone family, member J	molecular_function	Molecular function	-
TSPAN10	83882	tetraspanin 10	integral component of membrane	Cellular component	-
PTAFR	5724	platelet-activating factor receptor	intracellular membrane-bounded organelle	Cellular component	-
VASN	114990	vasorin	cellular response to redox state	Biological process	-
NSA2	10412	NSA2 ribosome biogenesis homolog (S. cerevisiae)	ribonucleoprotein complex	Cellular component	-
AHCYL1	10768	adenosylhomocysteinase-like 1	endoplasmic reticulum	Cellular component	-
THG1L	54974	tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)	protein homotetramerization	Biological process	21059936
CMAS	55907	cytidine monophosphate N-acetylneuraminic acid synthetase	post-translational protein modification	Biological process	-
WEE1	7465	WEE1 G2 checkpoint kinase	establishment of cell polarity	Biological process	-
COL4A4	1286	collagen, type IV, alpha 4	basal lamina	Cellular component	2211832
PPIAL4D	645142	peptidylprolyl isomerase A (cyclophilin A)-like 4D	protein folding	Biological process	-
EMP2	2013	epithelial membrane protein 2	positive regulation of cell proliferation	Biological process	24814193
SULF1	23213	sulfatase 1	cartilage development	Biological process	-
PPID	5481	peptidylprolyl isomerase D	cyclosporin A binding	Molecular function	7744028
PCDHGA2	56113	protocadherin gamma subfamily A, 2	plasma membrane	Cellular component	-
SLC4A2	6522	solute carrier family 4 (anion exchanger), member 2	chloride transmembrane transporter activity	Molecular function	-
PRMT1	3276	protein arginine methyltransferase 1	methyltransferase activity	Molecular function	9545638
RPL8	6132	ribosomal protein L8	focal adhesion	Cellular component	21423176
AVPR2	554	arginine vasopressin receptor 2	positive regulation of cell proliferation	Biological process	-
SPIRE1	56907	spire-type actin nucleation factor 1	cleavage furrow	Cellular component	-
RPA3	6119	replication protein A3, 14kDa	error-free translesion synthesis	Biological process	-
TNF	7124	tumor necrosis factor	positive regulation of smooth muscle cell proliferation	Biological process	16518841
CDC20	991	cell division cycle 20	regulation of meiotic nuclear division	Biological process	-
PDE2A	5138	phosphodiesterase 2A, cGMP-stimulated	cGMP catabolic process	Biological process	14687666
IKBKAP	8518	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein	Elongator holoenzyme complex	Cellular component	22854966
IFITM2	10581	interferon induced transmembrane protein 2	cytokine-mediated signaling pathway	Biological process	-
KDM3A	55818	lysine (K)-specific demethylase 3A	membrane	Cellular component	19946888
COPS6	10980	COP9 signalosome subunit 6	protein binding	Molecular function	16169070
PAN2	9924	PAN2 poly(A) specific ribonuclease subunit	gene expression	Biological process	-
CRLF1	9244	cytokine receptor-like factor 1	protein binding	Molecular function	10966616
PHACTR1	221692	phosphatase and actin regulator 1	actomyosin structure organization	Biological process	22976292
CPEB2	132864	cytoplasmic polyadenylation element binding protein 2	negative regulation of GTPase activity	Biological process	-
ADCY10	55811	adenylate cyclase 10 (soluble)	cytoplasm	Cellular component	9874775
SEC23B	10483	Sec23 homolog B (S. cerevisiae)	intracellular protein transport	Biological process	-
ITSN1	6453	intersectin 1 (SH3 domain protein)	Rho guanyl-nucleotide exchange factor activity	Molecular function	-
PPP2R3C	55012	protein phosphatase 2, regulatory subunit B'', gamma	cortical cytoskeleton organization	Biological process	-
NAT6	24142	N-acetyltransferase 6 (GCN5-related)	metabolic process	Biological process	-
PYROXD2	84795	pyridine nucleotide-disulphide oxidoreductase domain 2	protein binding	Molecular function	25416956
ICAM1	3383	intercellular adhesion molecule 1	negative regulation of endothelial cell apoptotic process	Biological process	10903502
HDAC2	3066	histone deacetylase 2	ATP-dependent chromatin remodeling	Biological process	16217013
RAPGEF3	10411	Rap guanine nucleotide exchange factor (GEF) 3	Rap guanyl-nucleotide exchange factor activity	Molecular function	21840392
EVX1	2128	even-skipped homeobox 1	sequence-specific DNA binding	Molecular function	-
ENG	2022	endoglin	extracellular matrix constituent secretion	Biological process	-
HOXD1	3231	homeobox D1	regulation of transcription, DNA-templated	Biological process	-
SF3A3	10946	splicing factor 3a, subunit 3, 60kDa	nuclear speck	Cellular component	-
DBNL	28988	drebrin-like	cytosol	Cellular component	-
SMAD4	4089	SMAD family member 4	regulation of hair follicle development	Biological process	-
SCPEP1	59342	serine carboxypeptidase 1	proteolysis	Biological process	-
PLEKHA2	59339	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2	lipid binding	Molecular function	-
MAPK1	5594	mitogen-activated protein kinase 1	cytosol	Cellular component	19565474
RAB38	23682	RAB38, member RAS oncogene family	GTPase activity	Molecular function	10910072
CETN2	1069	centrin, EF-hand protein, 2	photoreceptor connecting cilium	Cellular component	-
INPPL1	3636	inositol polyphosphate phosphatase-like 1	hydrolase activity	Molecular function	-
STIM1	6786	stromal interaction molecule 1	regulation of calcium ion transport	Biological process	16005298
CD38	952	CD38 molecule	response to drug	Biological process	17875758
HOXD11	3237	homeobox D11	proximal/distal pattern formation	Biological process	-
TTLL7	79739	tubulin tyrosine ligase-like family member 7	nervous system development	Biological process	-
ZBTB18	10472	zinc finger and BTB domain containing 18	DNA binding	Molecular function	9013868
P4HA1	5033	prolyl 4-hydroxylase, alpha polypeptide I	procollagen-proline 4-dioxygenase activity	Molecular function	-
PHLPP1	23239	PH domain and leucine rich repeat protein phosphatase 1	membrane	Cellular component	-
JAG1	182	jagged 1	aorta morphogenesis	Biological process	-
COMP	1311	cartilage oligomeric matrix protein	extracellular matrix structural constituent	Molecular function	-
SCYL1	57410	SCY1-like 1 (S. cerevisiae)	endoplasmic reticulum-Golgi intermediate compartment	Cellular component	18556652
CITED1	4435	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1	positive regulation of transforming growth factor beta receptor signaling pathway	Biological process	17336183
TNRC6B	23112	trinucleotide repeat containing 6B	poly(A) RNA binding	Molecular function	22658674
SETDB1	9869	SET domain, bifurcated 1	nuclear chromatin	Cellular component	-
COL4A3	1285	collagen, type IV, alpha 3 (Goodpasture antigen)	metalloendopeptidase inhibitor activity	Molecular function	10766752
CCL25	6370	chemokine (C-C motif) ligand 25	negative regulation of leukocyte tethering or rolling	Biological process	18308860
SLC24A3	57419	solute carrier family 24 (sodium/potassium/calcium exchanger), member 3	symporter activity	Molecular function	-
EMILIN1	11117	elastin microfibril interfacer 1	protein binding	Molecular function	11278945
IRF4	3662	interferon regulatory factor 4	protein-lysine N-methyltransferase activity	Molecular function	-
ATXN1L	342371	ataxin 1-like	lung alveolus development	Biological process	-
CLNK	116449	cytokine-dependent hematopoietic cell linker	transmembrane receptor protein tyrosine kinase signaling pathway	Biological process	-
PDIA6	10130	protein disulfide isomerase family A, member 6	endoplasmic reticulum	Cellular component	16130169
ITK	3702	IL2-inducible T-cell kinase	Fc-epsilon receptor signaling pathway	Biological process	-
SULF1	23213	sulfatase 1	innervation	Biological process	-
TTLL5	23093	tubulin tyrosine ligase-like family member 5	sperm motility	Biological process	-
BIRC3	330	baculoviral IAP repeat containing 3	negative regulation of reactive oxygen species metabolic process	Biological process	-
IGF1R	3480	insulin-like growth factor 1 receptor	phosphatidylinositol-mediated signaling	Biological process	7692086
SPAG8	26206	sperm associated antigen 8	nucleus	Cellular component	-
SMAD3	4088	SMAD family member 3	cytosol	Cellular component	-
CHMP4C	92421	charged multivesicular body protein 4C	viral process	Biological process	-
CCT4	10575	chaperonin containing TCP1, subunit 4 (delta)	ATP binding	Molecular function	-
OTUB2	78990	OTU deubiquitinase, ubiquitin aldehyde binding 2	nucleus	Cellular component	21630459
NEK9	91754	NIMA-related kinase 9	mitotic nuclear division	Biological process	-
XRCC4	7518	X-ray repair complementing defective repair in Chinese hamster cells 4	positive regulation of neurogenesis	Biological process	-
CHRM5	1133	cholinergic receptor, muscarinic 5	synaptic transmission, cholinergic	Biological process	-
JAG1	182	jagged 1	plasma membrane	Cellular component	-
CLIP1	6249	CAP-GLY domain containing linker protein 1	protein binding	Molecular function	11940666
ENG	2022	endoglin	wound healing	Biological process	18223685
DDR2	4921	discoidin domain receptor tyrosine kinase 2	extracellular exosome	Cellular component	23376485
GPATCH1	55094	G patch domain containing 1	mRNA splicing, via spliceosome	Biological process	11991638
ARID5A	10865	AT rich interactive domain 5A (MRF1-like)	nucleus	Cellular component	-
PGA4	643847	pepsinogen 4, group I (pepsinogen A)	digestion	Biological process	-
EGLN3	112399	egl-9 family hypoxia-inducible factor 3	protein binding	Molecular function	15721254
MYH14	79784	myosin, heavy chain 14, non-muscle	neuronal action potential	Biological process	21480433
RASGRP4	115727	RAS guanyl releasing protein 4	calcium ion binding	Molecular function	-
CENPJ	55835	centromere protein J	microtubule polymerization	Biological process	15047868
S100A7	6278	S100 calcium binding protein A7	extracellular exosome	Cellular component	23376485
FRMD5	84978	FERM domain containing 5	biological_process	Biological process	-
G6PC	2538	glucose-6-phosphatase, catalytic subunit	integral component of endoplasmic reticulum membrane	Cellular component	10318794
PRKDC	5591	protein kinase, DNA-activated, catalytic polypeptide	double-strand break repair via nonhomologous end joining	Biological process	-
RAC2	5880	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	positive regulation of cell proliferation	Biological process	-
AIFM1	9131	apoptosis-inducing factor, mitochondrion-associated, 1	DNA binding	Molecular function	-
BRMS1L	84312	breast cancer metastasis-suppressor 1-like	transcription, DNA-templated	Biological process	-
EIF4G1	1981	eukaryotic translation initiation factor 4 gamma, 1	cellular protein metabolic process	Biological process	-
WNT5A	7474	wingless-type MMTV integration site family, member 5A	positive regulation of inflammatory response	Biological process	18174455
ZPR1	8882	ZPR1 zinc finger	Gemini of coiled bodies	Cellular component	11283611
DAP	1611	death-associated protein	activation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	1087798
KIAA1549L	25758	KIAA1549-like	positive regulation of defense response to virus by host	Biological process	22020285
MRPL49	740	mitochondrial ribosomal protein L49	mitochondrial inner membrane	Cellular component	-
OCIAD1	54940	OCIA domain containing 1	protein binding	Molecular function	20195357
CCR7	1236	chemokine (C-C motif) receptor 7	positive regulation of cell-matrix adhesion	Biological process	15569314
CNOT6L	246175	CCR4-NOT transcription complex, subunit 6-like	regulation of translation	Biological process	-
RXRA	6256	retinoid X receptor, alpha	transcription initiation from RNA polymerase II promoter	Biological process	-
USP30	84749	ubiquitin specific peptidase 30	mitochondrial outer membrane	Cellular component	24896179
PIK3R4	30849	phosphoinositide-3-kinase, regulatory subunit 4	nuclear pore	Cellular component	-
HTR3C	170572	5-hydroxytryptamine (serotonin) receptor 3C, ionotropic	serotonin receptor signaling pathway	Biological process	17392525
LRRC8E	80131	leucine rich repeat containing 8 family, member E	plasma membrane	Cellular component	-
HTR6	3362	5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled	positive regulation of dopamine secretion	Biological process	-
CPSF6	11052	cleavage and polyadenylation specific factor 6, 68kDa	protein binding	Molecular function	14561889
FBXO22	26263	F-box protein 22	nucleus	Cellular component	-
CSK	1445	c-src tyrosine kinase	ATP binding	Molecular function	-
ZFPM2	23414	zinc finger protein, FOG family member 2	positive regulation of male gonad development	Biological process	-
P2RY4	5030	pyrimidinergic receptor P2Y, G-protein coupled, 4	plasma membrane	Cellular component	-
CREG1	8804	cellular repressor of E1A-stimulated genes 1	oxidoreductase activity	Molecular function	-
AKNA	80709	AT-hook transcription factor	membrane	Cellular component	19946888
CLCN7	1186	chloride channel, voltage-sensitive 7	transmembrane transport	Biological process	-
SYNE1	23345	spectrin repeat containing, nuclear envelope 1	integral component of membrane	Cellular component	11792814
STAU2	27067	staufen double-stranded RNA binding protein 2	nucleolus	Cellular component	-
ALG9	79796	ALG9, alpha-1,2-mannosyltransferase	post-translational protein modification	Biological process	-
MRC1	4360	mannose receptor, C type 1	receptor-mediated endocytosis	Biological process	20035344
CCDC141	285025	coiled-coil domain containing 141	protein binding	Molecular function	12812986
CCL3	6348	chemokine (C-C motif) ligand 3	positive chemotaxis	Biological process	10072545
SERPINF1	5176	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1	extracellular exosome	Cellular component	19056867
TSG101	7251	tumor susceptibility 101	protein binding	Molecular function	14505570
GTF2H2	2966	general transcription factor IIH, polypeptide 2, 44kDa	transcription from RNA polymerase II promoter	Biological process	-
SAT1	6303	spermidine/spermine N1-acetyltransferase 1	putrescine catabolic process	Biological process	-
HES2	54626	hes family bHLH transcription factor 2	negative regulation of transcription, DNA-templated	Biological process	-
CROT	54677	carnitine O-octanoyltransferase	intracellular membrane-bounded organelle	Cellular component	-
SYTL4	94121	synaptotagmin-like 4	Rab GTPase binding	Molecular function	-
UBC	7316	ubiquitin C	viral process	Biological process	-
APOE	348	apolipoprotein E	triglyceride catabolic process	Biological process	-
CA6	765	carbonic anhydrase VI	extracellular exosome	Cellular component	19199708
DNAJB9	4189	DnaJ (Hsp40) homolog, subfamily B, member 9	endoplasmic reticulum membrane	Cellular component	-
REV3L	5980	REV3-like, polymerase (DNA directed), zeta, catalytic subunit	3'-5' exonuclease activity	Molecular function	-
GNAS	2778	GNAS complex locus	developmental growth	Biological process	12719376
TSHB	7252	thyroid stimulating hormone, beta	cell-cell signaling	Biological process	2792087
CLIC2	1193	chloride intracellular channel 2	nucleus	Cellular component	16130169
XBP1	7494	X-box binding protein 1	response to endoplasmic reticulum stress	Biological process	11779464
ASS1	445	argininosuccinate synthase 1	response to zinc ion	Biological process	-
GNRH2	2797	gonadotropin-releasing hormone 2	multicellular organismal development	Biological process	-
PAPOLB	56903	poly(A) polymerase beta (testis specific)	metal ion binding	Molecular function	-
PTK2B	2185	protein tyrosine kinase 2 beta	lamellipodium	Cellular component	18765415
POU3F2	5454	POU class 3 homeobox 2	identical protein binding	Molecular function	11029584
FCER1A	2205	Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide	positive regulation of mast cell degranulation	Biological process	-
NME5	8382	NME/NM23 family member 5	ATP binding	Molecular function	-
OLFM4	10562	olfactomedin 4	regulation of apoptotic process	Biological process	23922742
KCNIP1	30820	Kv channel interacting protein 1	potassium channel activity	Molecular function	-
CCL11	6356	chemokine (C-C motif) ligand 11	mammary duct terminal end bud growth	Biological process	-
DCP1A	55802	decapping mRNA 1A	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	Biological process	-
HEPH	9843	hephaestin	ferroxidase activity	Molecular function	22961397
MLPH	79083	melanophilin	protein targeting	Biological process	-
CRHR2	1395	corticotropin releasing hormone receptor 2	negative regulation of cAMP-mediated signaling	Biological process	-
SCRIB	23513	scribbled planar cell polarity protein	protein binding	Molecular function	15182672
MSR1	4481	macrophage scavenger receptor 1	plasma membrane	Cellular component	-
FBXW7	55294	F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase	lung development	Biological process	-
VWA3A	146177	von Willebrand factor A domain containing 3A	extracellular region	Cellular component	-
UMOD	7369	uromodulin	neutrophil migration	Biological process	20798515
TGFB1	7040	transforming growth factor, beta 1	positive regulation of gene expression	Biological process	18625725
RINT1	60561	RAD50 interactor 1	regulation of ER to Golgi vesicle-mediated transport	Biological process	16571679
ACSS2	55902	acyl-CoA synthetase short-chain family member 2	acetate-CoA ligase activity	Molecular function	10843999
RORA	6095	RAR-related orphan receptor A	cellular response to hypoxia	Biological process	18658046
BCKDHB	594	branched chain keto acid dehydrogenase E1, beta polypeptide	protein binding	Molecular function	10745006
TNRC18	84629	trinucleotide repeat containing 18	mitochondrion	Cellular component	-
GTF2H1	2965	general transcription factor IIH, polypeptide 1, 62kDa	regulation of gene expression, epigenetic	Biological process	-
MEF2C	4208	myocyte enhancer factor 2C	blood vessel remodeling	Biological process	-
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	protein heterooligomerization	Biological process	-
EPHA3	2042	EPH receptor A3	ephrin receptor signaling pathway	Biological process	-
RHOB	388	ras homolog family member B	intracellular protein transport	Biological process	-
SIAE	54414	sialic acid acetylesterase	carbohydrate metabolic process	Biological process	23308225
PDPN	10630	podoplanin	inflammatory response	Biological process	-
CCR7	1236	chemokine (C-C motif) receptor 7	C-C motif chemokine 21 receptor activity	Molecular function	9507024
DHRS4	10901	dehydrogenase/reductase (SDR family) member 4	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	Molecular function	19442656
MS4A2	2206	membrane-spanning 4-domains, subfamily A, member 2	protein kinase binding	Molecular function	-
TJP1	7082	tight junction protein 1	basolateral plasma membrane	Cellular component	16427635
RPL6	6128	ribosomal protein L6	membrane	Cellular component	19946888
HIST4H4	121504	histone cluster 4, H4	DNA replication-dependent nucleosome assembly	Biological process	14718166
MYO1F	4542	myosin IF	regulation of actin cytoskeleton organization	Biological process	-
AKT2	208	v-akt murine thymoma viral oncogene homolog 2	cytosol	Cellular component	-
DDX19B	11269	DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B	nuclear pore	Cellular component	-
AP3S2	10239	adaptor-related protein complex 3, sigma 2 subunit	anterograde synaptic vesicle transport	Biological process	-
AP2B1	163	adaptor-related protein complex 2, beta 1 subunit	protein transporter activity	Molecular function	-
HIF1AN	55662	hypoxia inducible factor 1, alpha subunit inhibitor	cytoplasm	Cellular component	-
RAB25	57111	RAB25, member RAS oncogene family	positive regulation of epithelial cell migration	Biological process	22613965
FGFR3	2261	fibroblast growth factor receptor 3	alveolar secondary septum development	Biological process	-
TREH	11181	trehalase (brush-border membrane glycoprotein)	organ morphogenesis	Biological process	-
TOPORS	10210	topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase	cellular response to DNA damage stimulus	Biological process	15735665
SLC39A6	25800	solute carrier family 39 (zinc transporter), member 6	lamellipodium membrane	Cellular component	12839489
MAGEA11	4110	melanoma antigen family A11	nucleus	Cellular component	-
SBF2	81846	SET binding factor 2	Rab guanyl-nucleotide exchange factor activity	Molecular function	20937701
MYO1D	4642	myosin ID	actin-dependent ATPase activity	Molecular function	-
LRPPRC	10128	leucine-rich pentatricopeptide repeat containing	poly(A) RNA binding	Molecular function	22658674
LAMA2	3908	laminin, alpha 2	extracellular exosome	Cellular component	23376485
ABL2	27	ABL proto-oncogene 2, non-receptor tyrosine kinase	positive regulation of interleukin-2 secretion	Biological process	-
KCNC1	3746	potassium channel, voltage gated Shaw related subfamily C, member 1	voltage-gated potassium channel complex	Cellular component	-
DFFA	1676	DNA fragmentation factor, 45kDa, alpha polypeptide	negative regulation of apoptotic DNA fragmentation	Biological process	15572351
CBS	875	cystathionine-beta-synthase	oxidation-reduction process	Biological process	24416422
CRH	1392	corticotropin releasing hormone	positive regulation of corticotropin secretion	Biological process	-
RBM5	10181	RNA binding motif protein 5	poly(A) RNA binding	Molecular function	22681889
CREB3	10488	cAMP responsive element binding protein 3	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	16940180
ITGA2B	3674	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	extracellular matrix binding	Molecular function	-
CYP11A1	1583	cytochrome P450, family 11, subfamily A, polypeptide 1	mitochondrial matrix	Cellular component	-
UGT1A4	54657	UDP glucuronosyltransferase 1 family, polypeptide A4	negative regulation of cellular glucuronidation	Biological process	20610558
SYDE1	85360	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)	synaptonemal complex assembly	Biological process	-
ZMAT5	55954	zinc finger, matrin-type 5	nucleoplasm	Cellular component	-
HLA-C	3107	major histocompatibility complex, class I, C	phagocytic vesicle membrane	Cellular component	-
DNMT1	1786	DNA (cytosine-5-)-methyltransferase 1	positive regulation of histone H3-K4 methylation	Biological process	18413740
TRPV2	51393	transient receptor potential cation channel, subfamily V, member 2	sensory perception	Biological process	10201375
INSR	3643	insulin receptor	positive regulation of protein kinase B signaling	Biological process	11500939
HECTD1	25831	HECT domain containing E3 ubiquitin protein ligase 1	neural tube closure	Biological process	-
IFNK	56832	interferon, kappa	response to exogenous dsRNA	Biological process	-
CA5B	11238	carbonic anhydrase VB, mitochondrial	carbonate dehydratase activity	Molecular function	-
KCNB2	9312	potassium channel, voltage gated Shab related subfamily B, member 2	protein homooligomerization	Biological process	-
LGR5	8549	leucine-rich repeat containing G protein-coupled receptor 5	inner ear development	Biological process	-
DSCC1	79075	DNA replication and sister chromatid cohesion 1	post-translational protein acetylation	Biological process	19907496
FGG	2266	fibrinogen gamma chain	platelet alpha granule lumen	Cellular component	-
C10orf99	387695	chromosome 10 open reading frame 99	extracellular space	Cellular component	-
SIDT1	54847	SID1 transmembrane family, member 1	RNA transmembrane transporter activity	Molecular function	-
OR4K2	390431	olfactory receptor, family 4, subfamily K, member 2	transmembrane signaling receptor activity	Molecular function	-
PLEKHG7	440107	pleckstrin homology domain containing, family G (with RhoGef domain) member 7	Rho guanyl-nucleotide exchange factor activity	Molecular function	-
FMNL3	91010	formin-like 3	cytoskeleton organization	Biological process	21834987
LAMTOR5	10542	late endosomal/lysosomal adaptor, MAPK and MTOR activator 5	regulation of cell size	Biological process	22980980
HACD3	51495	3-hydroxyacyl-CoA dehydratase 3	fatty acid elongation	Biological process	18554506
CACNA1C	775	calcium channel, voltage-dependent, L type, alpha 1C subunit	small molecule metabolic process	Biological process	-
ERGIC3	51614	ERGIC and golgi 3	endoplasmic reticulum-Golgi intermediate compartment membrane	Cellular component	-
NOL8	55035	nucleolar protein 8	rRNA processing	Biological process	16963496
TYRP1	7306	tyrosinase-related protein 1	oxidation-reduction process	Biological process	-
HIP1	3092	huntingtin interacting protein 1	membrane	Cellular component	9147654
CREB1	1385	cAMP responsive element binding protein 1	toll-like receptor 10 signaling pathway	Biological process	-
FHOD1	29109	formin homology 2 domain containing 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	15095401
SENP2	59343	SUMO1/sentrin/SMT3 specific peptidase 2	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
CCL3	6348	chemokine (C-C motif) ligand 3	astrocyte cell migration	Biological process	-
EGF	1950	epidermal growth factor	blood coagulation	Biological process	-
ANGPTL3	27329	angiopoietin-like 3	cell-matrix adhesion	Biological process	11877390
LTA	4049	lymphotoxin alpha	negative regulation of growth of symbiont in host	Biological process	-
H2AFB1	474382	H2A histone family, member B1	nucleus	Cellular component	21630459
SRSF1	6426	serine/arginine-rich splicing factor 1	mRNA export from nucleus	Biological process	-
NSMCE1	197370	non-SMC element 1 homolog (S. cerevisiae)	cytoplasm	Cellular component	-
F8A3	474384	coagulation factor VIII-associated 3	nucleus	Cellular component	-
MYLK	4638	myosin light chain kinase	extracellular exosome	Cellular component	23376485
TRIM29	23650	tripartite motif containing 29	negative regulation of protein localization to nucleus	Biological process	-
VTI1A	143187	vesicle transport through interaction with t-SNAREs 1A	integral component of membrane	Cellular component	-
NR0B1	190	nuclear receptor subfamily 0, group B, member 1	Leydig cell differentiation	Biological process	-
PLD6	201164	phospholipase D family, member 6	lipid catabolic process	Biological process	-
PPP1R7	5510	protein phosphatase 1, regulatory subunit 7	chromosome segregation	Biological process	-
CST3	1471	cystatin C	perinuclear region of cytoplasm	Cellular component	-
FGF16	8823	fibroblast growth factor 16	cell-cell signaling	Biological process	9473496
CSNK1A1	1452	casein kinase 1, alpha 1	cytosol	Cellular component	-
ASMT	438	acetylserotonin O-methyltransferase	small molecule metabolic process	Biological process	-
TK2	7084	thymidine kinase 2, mitochondrial	nucleobase-containing small molecule metabolic process	Biological process	-
GGTA1P	2681	glycoprotein, alpha-galactosyltransferase 1 pseudogene	anchored component of external side of plasma membrane	Cellular component	18357469
ADORA2A	135	adenosine A2a receptor	axolemma	Cellular component	-
THBS1	7057	thrombospondin 1	external side of plasma membrane	Cellular component	6777381
PSME1	5720	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)	negative regulation of apoptotic process	Biological process	-
NCKAP1	10787	NCK-associated protein 1	integral component of membrane	Cellular component	-
GABRG3	2567	gamma-aminobutyric acid (GABA) A receptor, gamma 3	synaptic transmission	Biological process	-
PLCB1	23236	phospholipase C, beta 1 (phosphoinositide-specific)	nuclear chromatin	Cellular component	-
CSNK2A1	1457	casein kinase 2, alpha 1 polypeptide	Wnt signaling pathway	Biological process	-
ARMCX3	51566	armadillo repeat containing, X-linked 3	cellular protein localization	Biological process	-
OR6T1	219874	olfactory receptor, family 6, subfamily T, member 1	olfactory receptor activity	Molecular function	-
TRIP13	9319	thyroid hormone receptor interactor 13	spermatogenesis	Biological process	-
GALNT10	55568	polypeptide N-acetylgalactosaminyltransferase 10	cellular protein metabolic process	Biological process	-
TUBAL3	79861	tubulin, alpha-like 3	cytoplasm	Cellular component	-
TRPV4	59341	transient receptor potential cation channel, subfamily V, member 4	vasopressin secretion	Biological process	-
PER2	8864	period circadian clock 2	glycogen biosynthetic process	Biological process	-
ALS2	57679	amyotrophic lateral sclerosis 2 (juvenile)	positive regulation of protein serine/threonine kinase activity	Biological process	16049005
DOK5	55816	docking protein 5	intracellular	Cellular component	-
P2RY1	5028	purinergic receptor P2Y, G-protein coupled, 1	cell body	Cellular component	-
SPHK1	8877	sphingosine kinase 1	DNA binding	Molecular function	12393916
RPS15	6209	ribosomal protein S15	viral life cycle	Biological process	-
HOXA1	3198	homeobox A1	cochlea morphogenesis	Biological process	16155570
SNTA1	6640	syntrophin, alpha 1	ventricular cardiac muscle cell action potential	Biological process	18591664
STMN1	3925	stathmin 1	neuron projection development	Biological process	-
CRYL1	51084	crystallin, lambda 1	3-hydroxyacyl-CoA dehydrogenase activity	Molecular function	-
LAG3	3902	lymphocyte-activation gene 3	positive regulation of natural killer cell mediated cytotoxicity	Biological process	-
NDUFAF6	137682	NADH dehydrogenase (ubiquinone) complex I, assembly factor 6	cytoplasm	Cellular component	22019594
NR1I3	9970	nuclear receptor subfamily 1, group I, member 3	DNA binding	Molecular function	9783588
HINFP	25988	histone H4 transcription factor	protein binding	Molecular function	11553631
APOA4	337	apolipoprotein A-IV	response to stilbenoid	Biological process	-
B2M	567	beta-2-microglobulin	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent	Biological process	-
DSCAM	1826	Down syndrome cell adhesion molecule	positive regulation of axon extension involved in axon guidance	Biological process	18585357
IDO1	3620	indoleamine 2,3-dioxygenase 1	positive regulation of T cell tolerance induction	Biological process	-
BLOC1S2	282991	biogenesis of lysosomal organelles complex-1, subunit 2	positive regulation of cell proliferation	Biological process	15381421
AP1G1	164	adaptor-related protein complex 1, gamma 1 subunit	Golgi to lysosome transport	Biological process	23632890
MBD3L3	653657	methyl-CpG binding domain protein 3-like 3	regulation of transcription, DNA-templated	Biological process	-
PPP2R2D	55844	protein phosphatase 2, regulatory subunit B, delta	protein phosphatase type 2A regulator activity	Molecular function	-
PDP2	57546	pyruvate dehyrogenase phosphatase catalytic subunit 2	metal ion binding	Molecular function	-
SLC2A8	29988	solute carrier family 2 (facilitated glucose transporter), member 8	plasma membrane	Cellular component	-
FAF2	23197	Fas associated factor family member 2	intracellular membrane-bounded organelle	Cellular component	-
UGT1A9	54600	UDP glucuronosyltransferase 1 family, polypeptide A9	endoplasmic reticulum	Cellular component	20610558
SYT5	6861	synaptotagmin V	cell junction	Cellular component	-
PTGS2	5743	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	positive regulation of fibroblast growth factor production	Biological process	9630216
B3GAT1	27087	beta-1,3-glucuronyltransferase 1	chondroitin sulfate metabolic process	Biological process	-
CDKAL1	54901	CDK5 regulatory subunit associated protein 1-like 1	protein binding	Molecular function	25416956
ADAM19	8728	ADAM metallopeptidase domain 19	metalloendopeptidase activity	Molecular function	-
HSD17B12	51144	hydroxysteroid (17-beta) dehydrogenase 12	endoplasmic reticulum membrane	Cellular component	-
MLH1	4292	mutL homolog 1	ATP binding	Molecular function	-
POLR2J3	548644	polymerase (RNA) II (DNA directed) polypeptide J3	RNA polymerase II activity	Molecular function	-
HTR7	3363	5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled	vasoconstriction	Biological process	-
AP1AR	55435	adaptor-related protein complex 1 associated regulatory protein	negative regulation of substrate adhesion-dependent cell spreading	Biological process	22689987
TPT1	7178	tumor protein, translationally-controlled 1	negative regulation of apoptotic process	Biological process	16130169
RRAS	6237	related RAS viral (r-ras) oncogene homolog	protein complex binding	Molecular function	23209302
SF3B2	10992	splicing factor 3b, subunit 2, 145kDa	gene expression	Biological process	-
RABGAP1	23637	RAB GTPase activating protein 1	DNA binding	Molecular function	-
SLC11A2	4891	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2	manganese ion transport	Biological process	17109629
CLCNKB	1188	chloride channel, voltage-sensitive Kb	metal ion binding	Molecular function	-
ELAVL1	1994	ELAV like RNA binding protein 1	3'-UTR-mediated mRNA stabilization	Biological process	19029303
IFT140	9742	intraflagellar transport 140	molecular_function	Molecular function	-
POU5F1	5460	POU class 5 homeobox 1	blastocyst development	Biological process	-
ARHGAP5	394	Rho GTPase activating protein 5	Rho protein signal transduction	Biological process	8537347
GPR141	353345	G protein-coupled receptor 141	integral component of membrane	Cellular component	-
EXOSC8	11340	exosome component 8	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	Biological process	-
CFL2	1073	cofilin 2 (muscle)	extracellular space	Cellular component	23580065
ABCA12	26154	ATP-binding cassette, sub-family A (ABC1), member 12	ceramide transport	Biological process	-
SPATA5	166378	spermatogenesis associated 5	cytoplasm	Cellular component	-
TRPS1	7227	trichorhinophalangeal syndrome I	protein binding	Molecular function	12885770
SIRPB1	10326	signal-regulatory protein beta 1	signal transduction	Biological process	9062191
OR4E1	26687	olfactory receptor, family 4, subfamily E, member 1 (gene/pseudogene)	G-protein coupled receptor activity	Molecular function	-
EEA1	8411	early endosome antigen 1	cytosol	Cellular component	7768953
RP2	6102	retinitis pigmentosa 2 (X-linked recessive)	protein binding	Molecular function	11847227
RPS15A	6210	ribosomal protein S15a	extracellular exosome	Cellular component	20458337
TNFSF4	7292	tumor necrosis factor (ligand) superfamily, member 4	positive regulation of cell proliferation	Biological process	7913952
AP1S2	8905	adaptor-related protein complex 1, sigma 2 subunit	regulation of defense response to virus by virus	Biological process	-
AIM2	9447	absent in melanoma 2	interleukin-1 beta secretion	Biological process	19158679
SOD2	6648	superoxide dismutase 2, mitochondrial	mitochondrial matrix	Cellular component	10511315
TGFB2	7042	transforming growth factor, beta 2	positive regulation of neuron apoptotic process	Biological process	16227582
PPAPDC3	84814	phosphatidic acid phosphatase type 2 domain containing 3	metabolic process	Biological process	-
SPOCK2	9806	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2	extracellular matrix binding	Molecular function	-
GDF7	151449	growth differentiation factor 7	branching morphogenesis of an epithelial tube	Biological process	-
TGFB1	7040	transforming growth factor, beta 1	epidermal growth factor receptor signaling pathway	Biological process	18625725
CDC123	8872	cell division cycle 123	cell cycle arrest	Biological process	8601400
BCL6	604	B-cell CLL/lymphoma 6	chromatin DNA binding	Molecular function	-
ABLIM3	22885	actin binding LIM protein family, member 3	axon guidance	Biological process	-
POLR2G	5436	polymerase (RNA) II (DNA directed) polypeptide G	piRNA metabolic process	Biological process	-
NFKB1	4790	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	cellular response to lipopolysaccharide	Biological process	23776175
ADH5	128	alcohol dehydrogenase 5 (class III), chi polypeptide	electron carrier activity	Molecular function	8460164
FNDC1	84624	fibronectin type III domain containing 1	nucleoplasm	Cellular component	-
GPR34	2857	G protein-coupled receptor 34	integral component of plasma membrane	Cellular component	10036181
PARP2	10038	poly (ADP-ribose) polymerase 2	DNA repair	Biological process	7260241
TRIM71	131405	tripartite motif containing 71, E3 ubiquitin protein ligase	positive regulation of gene silencing by miRNA	Biological process	-
ZFPM1	161882	zinc finger protein, FOG family member 1	mitral valve formation	Biological process	-
FASTKD5	60493	FAST kinase domains 5	cellular respiration	Biological process	20869947
PRDM1	639	PR domain containing 1, with ZNF domain	metal ion binding	Molecular function	-
C1RL	51279	complement component 1, r subcomponent-like	serine-type endopeptidase activity	Molecular function	-
CYGB	114757	cytoglobin	iron ion binding	Molecular function	-
AGO3	192669	argonaute RISC catalytic component 3	Fc-epsilon receptor signaling pathway	Biological process	-
PLXNB2	23654	plexin B2	regulation of neuron migration	Biological process	-
SCN1A	6323	sodium channel, voltage gated, type I alpha subunit	neuromuscular process controlling posture	Biological process	-
SLC22A20	440044	solute carrier family 22, member 20	transmembrane transporter activity	Molecular function	-
RABL2B	11158	RAB, member of RAS oncogene family-like 2B	Rab protein signal transduction	Biological process	-
HELZ2	85441	helicase with zinc finger 2, transcriptional coactivator	helicase activity	Molecular function	-
TERF1	7013	telomeric repeat binding factor (NIMA-interacting) 1	spindle	Cellular component	-
COLEC12	81035	collectin sub-family member 12	positive regulation of cell adhesion molecule production	Biological process	25204797
HRH2	3274	histamine receptor H2	gastrin-induced gastric acid secretion	Biological process	-
ZNF713	349075	zinc finger protein 713	metal ion binding	Molecular function	-
GNGT1	2792	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	regulation of rhodopsin mediated signaling pathway	Biological process	-
TRMT2A	27037	tRNA methyltransferase 2 homolog A (S. cerevisiae)	RNA methyltransferase activity	Molecular function	-
PSMA4	5685	proteasome (prosome, macropain) subunit, alpha type, 4	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	Biological process	-
RAC1	5879	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	response to wounding	Biological process	9572733
ITIH3	3699	inter-alpha-trypsin inhibitor heavy chain 3	extracellular exosome	Cellular component	23533145
OR51V1	283111	olfactory receptor, family 51, subfamily V, member 1	detection of chemical stimulus involved in sensory perception of smell	Biological process	11121057
MTA2	9219	metastasis associated 1 family, member 2	transcription factor complex	Cellular component	15920471
PELO	53918	pelota homolog (Drosophila)	cell proliferation	Biological process	-
RNF41	10193	ring finger protein 41, E3 ubiquitin protein ligase	negative regulation of cell migration	Biological process	17145873
ABCG5	64240	ATP-binding cassette, sub-family G (WHITE), member 5	response to ionizing radiation	Biological process	-
CREBRF	153222	CREB3 regulatory factor	maternal behavior	Biological process	-
SETD6	79918	SET domain containing 6	NF-kappaB binding	Molecular function	21131967
PPARGC1A	10891	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
RGPD8	727851	RANBP2-like and GRIP domain containing 8	nuclear pore	Cellular component	9480752
ZNF710	374655	zinc finger protein 710	transcription, DNA-templated	Biological process	-
CYP2E1	1571	cytochrome P450, family 2, subfamily E, polypeptide 1	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	Molecular function	18818195
THBD	7056	thrombomodulin	signal transduction	Biological process	-
SLC25A6	293	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6	protein binding	Molecular function	21370995
PDLIM1	9124	PDZ and LIM domain 1	transcription coactivator activity	Molecular function	-
NEDD4	4734	neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase	adaptive immune response	Biological process	-
KRT16	3868	keratin 16, type I	inflammatory response	Biological process	-
STK4	6789	serine/threonine kinase 4	magnesium ion binding	Molecular function	8566796
SOX9	6662	SRY (sex determining region Y)-box 9	nucleosome assembly	Biological process	20484372
PTGFR	5737	prostaglandin F receptor (FP)	G-protein coupled receptor signaling pathway	Biological process	-
P2RX7	5027	purinergic receptor P2X, ligand gated ion channel, 7	bleb	Cellular component	-
CHRM2	1129	cholinergic receptor, muscarinic 2	positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway	Biological process	-
P4HA2	8974	prolyl 4-hydroxylase, alpha polypeptide II	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	Molecular function	-
CIAPIN1	57019	cytokine induced apoptosis inhibitor 1	metal ion binding	Molecular function	-
EIF2S2	8894	eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa	poly(A) RNA binding	Molecular function	22658674
ZC3HC1	51530	zinc finger, C3HC-type containing 1	nuclear membrane	Cellular component	-
COPE	11316	coatomer protein complex, subunit epsilon	protein binding	Molecular function	25416956
CHST9	83539	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9	hormone biosynthetic process	Biological process	-
MIF	4282	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	cytoplasm	Cellular component	-
DHRS2	10202	dehydrogenase/reductase (SDR family) member 2	cellular response to oxidative stress	Biological process	19443906
MYEF2	50804	myelin expression factor 2	poly(A) RNA binding	Molecular function	22681889
SOX11	6664	SRY (sex determining region Y)-box 11	negative regulation of glial cell proliferation	Biological process	19808959
GALNT16	57452	polypeptide N-acetylgalactosaminyltransferase 16	protein glycosylation	Biological process	-
CTBP2	1488	C-terminal binding protein 2	viral genome replication	Biological process	9479502
WEE2	494551	WEE1 homolog 2 (S. pombe)	mitotic nuclear division	Biological process	-
LHX8	431707	LIM homeobox 8	female gonad development	Biological process	-
CIB1	10519	calcium and integrin binding 1 (calmyrin)	endomitotic cell cycle	Biological process	21264284
ARL2BP	23568	ADP-ribosylation factor-like 2 binding protein	nucleus	Cellular component	-
MLXIPL	51085	MLX interacting protein-like	cytosol	Cellular component	-
CAMK4	814	calcium/calmodulin-dependent protein kinase IV	peptidyl-serine phosphorylation	Biological process	-
DDC	1644	dopa decarboxylase (aromatic L-amino acid decarboxylase)	aromatic-L-amino-acid decarboxylase activity	Molecular function	-
APAF1	317	apoptotic peptidase activating factor 1	intrinsic apoptotic signaling pathway	Biological process	18309324
ATP5G1	516	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)	ATP hydrolysis coupled proton transport	Biological process	-
FBXO40	51725	F-box protein 40	molecular_function	Molecular function	-
TOP2A	7153	topoisomerase (DNA) II alpha 170kDa	cellular response to DNA damage stimulus	Biological process	16611985
BMP10	27302	bone morphogenetic protein 10	positive regulation of cardiac muscle hypertrophy	Biological process	17921333
IKBKE	9641	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	mitochondrial membrane	Cellular component	16876765
CRYL1	51084	crystallin, lambda 1	oxidation-reduction process	Biological process	-
MAPK11	5600	mitogen-activated protein kinase 11	neurotrophin TRK receptor signaling pathway	Biological process	-
RIMS4	140730	regulating synaptic membrane exocytosis 4	cell junction	Cellular component	-
UQCRB	7381	ubiquinol-cytochrome c reductase binding protein	mitochondrial electron transport, ubiquinol to cytochrome c	Biological process	-
APOA2	336	apolipoprotein A-II	apolipoprotein receptor binding	Molecular function	11162594
ATF7IP	55729	activating transcription factor 7 interacting protein	transcription factor complex	Cellular component	-
MOV10	4343	Mov10 RISC complex RNA helicase	ATP binding	Molecular function	-
TXK	7294	TXK tyrosine kinase	protein phosphorylation	Biological process	17177976
UTF1	8433	undifferentiated embryonic cell transcription factor 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	9748258
PLEKHA7	144100	pleckstrin homology domain containing, family A member 7	cytoplasm	Cellular component	-
RAP1A	5906	RAP1A, member of RAS oncogene family	positive regulation of ERK1 and ERK2 cascade	Biological process	-
FRRS1L	23732	ferric-chelate reductase 1-like	biological_process	Biological process	-
HIST3H2A	92815	histone cluster 3, H2a	nucleosome disassembly	Biological process	22334663
SLC25A4	291	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4	transmembrane transport	Biological process	-
NAALADL1	10004	N-acetylated alpha-linked acidic dipeptidase-like 1	peptidase activity	Molecular function	9388249
PCK1	5105	phosphoenolpyruvate carboxykinase 1 (soluble)	glucose homeostasis	Biological process	-
POU2F2	5452	POU class 2 homeobox 2	protein domain specific binding	Molecular function	-
LYN	4067	LYN proto-oncogene, Src family tyrosine kinase	signal transduction	Biological process	7650013
COL5A1	1289	collagen, type V, alpha 1	endoplasmic reticulum lumen	Cellular component	-
VPS33A	65082	vacuolar protein sorting 33 homolog A (S. cerevisiae)	late endosome membrane	Cellular component	-
NCBP2	22916	nuclear cap binding protein subunit 2, 20kDa	nucleotide binding	Molecular function	-
CD2	914	CD2 molecule	blood coagulation	Biological process	-
STXBP1	6812	syntaxin binding protein 1	syntaxin binding	Molecular function	12773094
LAT	27040	linker for activation of T cells	Ras protein signal transduction	Biological process	12646565
TRIM56	81844	tripartite motif containing 56	zinc ion binding	Molecular function	-
UVRAG	7405	UV radiation resistance associated	regulation of vesicle-mediated transport	Biological process	-
FHL2	2274	four and a half LIM domains 2	Z disc	Cellular component	-
PLXDC1	57125	plexin domain containing 1	neuronal cell body	Cellular component	-
CALR	811	calreticulin	post-translational protein modification	Biological process	-
MTA2	9219	metastasis associated 1 family, member 2	nucleosomal DNA binding	Molecular function	16217013
LY6E	4061	lymphocyte antigen 6 complex, locus E	cell surface receptor signaling pathway	Biological process	8650192
FBXO2	26232	F-box protein 2	carbohydrate binding	Molecular function	-
SRGAP1	57522	SLIT-ROBO Rho GTPase activating protein 1	GTPase activator activity	Molecular function	-
AP2A1	160	adaptor-related protein complex 2, alpha 1 subunit	clathrin-coated endocytic vesicle membrane	Cellular component	-
BLOC1S6	26258	biogenesis of lysosomal organelles complex-1, subunit 6, pallidin	SNARE complex	Cellular component	19546860
ISL1	3670	ISL LIM homeobox 1	positive regulation of interleukin-12 production	Biological process	-
ATP6V1G2	534	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2	insulin receptor signaling pathway	Biological process	-
VIPAS39	63894	VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog	recycling endosome	Cellular component	19109425
SERPINA5	5104	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5	extracellular region	Cellular component	11120760
PHKB	5257	phosphorylase kinase, beta	calmodulin binding	Molecular function	-
MAPK8	5599	mitogen-activated protein kinase 8	peptidyl-serine phosphorylation	Biological process	15850461
TBX5	6910	T-box 5	cardiac muscle cell differentiation	Biological process	-
MINPP1	9562	multiple inositol-polyphosphate phosphatase 1	extracellular exosome	Cellular component	23376485
MTG1	92170	mitochondrial ribosome-associated GTPase 1	metabolic process	Biological process	23396448
SKA3	221150	spindle and kinetochore associated complex subunit 3	condensed chromosome outer kinetochore	Cellular component	19289083
LRRTM4	80059	leucine rich repeat transmembrane neuronal 4	alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering	Biological process	-
CDK2	1017	cyclin-dependent kinase 2	mitotic G1 DNA damage checkpoint	Biological process	21319273
NT5C1A	84618	5'-nucleotidase, cytosolic IA	small molecule metabolic process	Biological process	-
VANGL2	57216	VANGL planar cell polarity protein 2	plasma membrane	Cellular component	-
YES1	7525	YES proto-oncogene 1, Src family tyrosine kinase	focal adhesion	Cellular component	21423176
UPF1	5976	UPF1 regulator of nonsense transcripts homolog (yeast)	nuclear-transcribed mRNA catabolic process	Biological process	23828042
DGKI	9162	diacylglycerol kinase, iota	nucleus	Cellular component	9830018
MYADM	91663	myeloid-associated differentiation marker	integral component of membrane	Cellular component	-
CEP55	55165	centrosomal protein 55kDa	cell separation after cytokinesis	Biological process	20616062
NLGN1	22871	neuroligin 1	protein dimerization activity	Molecular function	-
UBQLN2	29978	ubiquilin 2	nucleus	Cellular component	-
ADAMTS14	140766	ADAM metallopeptidase with thrombospondin type 1 motif, 14	proteinaceous extracellular matrix	Cellular component	-
DSCR3	10311	Down syndrome critical region 3	molecular_function	Molecular function	-
PRKAA1	5562	protein kinase, AMP-activated, alpha 1 catalytic subunit	cellular response to ethanol	Biological process	-
SLC44A5	204962	solute carrier family 44, member 5	phosphatidylcholine biosynthetic process	Biological process	-
FLNA	2316	filamin A, alpha	cell junction assembly	Biological process	-
KDM4D	55693	lysine (K)-specific demethylase 4D	histone H3-K9 demethylation	Biological process	25124442
KIF21B	23046	kinesin family member 21B	ATPase activity	Molecular function	-
TACC2	10579	transforming, acidic coiled-coil containing protein 2	astral microtubule organization	Biological process	-
RGL2	5863	ral guanine nucleotide dissociation stimulator-like 2	Ras protein signal transduction	Biological process	8976381
PNLIPRP2	5408	pancreatic lipase-related protein 2	extracellular region	Cellular component	-
DOT1L	84444	DOT1-like histone H3K79 methyltransferase	transcription factor binding	Molecular function	22002246
ADAMTS10	81794	ADAM metallopeptidase with thrombospondin type 1 motif, 10	protein binding	Molecular function	21402694
ARSD	414	arylsulfatase D	small molecule metabolic process	Biological process	-
CD5	921	CD5 molecule	cell recognition	Biological process	1711157
BLOC1S2	282991	biogenesis of lysosomal organelles complex-1, subunit 2	neuron projection development	Biological process	-
NFIA	4774	nuclear factor I/A	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
DDX39B	7919	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B	nucleus	Cellular component	21859714
MRC1	4360	mannose receptor, C type 1	cellular response to interleukin-4	Biological process	-
PLXND1	23129	plexin D1	patterning of blood vessels	Biological process	-
SLC9A3	6550	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3	protein binding	Molecular function	16159897
SENP5	205564	SUMO1/sentrin specific peptidase 5	nucleus	Cellular component	-
ALKBH4	54784	alkB, alkylation repair homolog 4 (E. coli)	cytoplasm	Cellular component	-
GNAT3	346562	guanine nucleotide binding protein, alpha transducing 3	metal ion binding	Molecular function	-
TOR1A	1861	torsin family 1, member A (torsin A)	unfolded protein binding	Molecular function	-
NTRK1	4914	neurotrophic tyrosine kinase, receptor, type 1	negative regulation of neuron apoptotic process	Biological process	-
TWF1	5756	twinfilin actin-binding protein 1	ruffle membrane	Cellular component	12807912
VPS37B	79720	vacuolar protein sorting 37 homolog B (S. cerevisiae)	extracellular exosome	Cellular component	19056867
AGTR2	186	angiotensin II receptor, type 2	negative regulation of norepinephrine secretion	Biological process	-
MBD3L1	85509	methyl-CpG binding domain protein 3-like 1	cytoplasm	Cellular component	-
TMEM109	79073	transmembrane protein 109	cellular response to gamma radiation	Biological process	23542032
PDX1	3651	pancreatic and duodenal homeobox 1	cytosol	Cellular component	-
USP34	9736	ubiquitin specific peptidase 34	protein deubiquitination	Biological process	14715245
RBBP7	5931	retinoblastoma binding protein 7	protein binding	Molecular function	-
ZDHHC19	131540	zinc finger, DHHC-type containing 19	zinc ion binding	Molecular function	-
SLAMF7	57823	SLAM family member 7	cell adhesion	Biological process	11802771
PICALM	8301	phosphatidylinositol binding clathrin assembly protein	AP-2 adaptor complex	Cellular component	16262731
KDM8	79831	lysine (K)-specific demethylase 8	chromatin binding	Molecular function	20457893
SERPINF1	5176	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1	aging	Biological process	-
CD58	965	CD58 molecule	membrane	Cellular component	19946888
SOX4	6659	SRY (sex determining region Y)-box 4	pro-B cell differentiation	Biological process	-
KCNQ3	3786	potassium channel, voltage gated KQT-like subfamily Q, member 3	integral component of membrane	Cellular component	-
GGNBP2	79893	gametogenetin binding protein 2	multicellular organismal development	Biological process	-
PRSS1	5644	protease, serine, 1 (trypsin 1)	extracellular space	Cellular component	-
ZNF354B	117608	zinc finger protein 354B	metal ion binding	Molecular function	-
PRPF31	26121	pre-mRNA processing factor 31	nuclear speck	Cellular component	11867543
MGLL	11343	monoglyceride lipase	acylglycerol acyl-chain remodeling	Biological process	-
CTBP1	1487	C-terminal binding protein 1	protein phosphorylation	Biological process	8440238
ACTA1	58	actin, alpha 1, skeletal muscle	skeletal muscle fiber adaptation	Biological process	-
BMP2	650	bone morphogenetic protein 2	Notch signaling pathway	Biological process	-
FOXRED2	80020	FAD-dependent oxidoreductase domain containing 2	glycoprotein binding	Molecular function	21359175
ALG6	29929	ALG6, alpha-1,3-glucosyltransferase	cellular protein metabolic process	Biological process	-
HYAL1	3373	hyaluronoglucosaminidase 1	response to reactive oxygen species	Biological process	20554532
FLOT1	10211	flotillin 1	positive regulation of cytokine production	Biological process	25204797
RBBP5	5929	retinoblastoma binding protein 5	transcription regulatory region DNA binding	Molecular function	16603732
TBCCD1	55171	TBCC domain containing 1	regulation of cell shape	Biological process	20168327
HBB	3043	hemoglobin, beta	positive regulation of nitric oxide biosynthetic process	Biological process	7965120
VBP1	7411	von Hippel-Lindau binding protein 1	'de novo' posttranslational protein folding	Biological process	-
TNN	63923	tenascin N	axonogenesis	Biological process	-
ZNF645	158506	zinc finger protein 645	ubiquitin protein ligase activity	Molecular function	-
RDH10	157506	retinol dehydrogenase 10 (all-trans)	visual perception	Biological process	12407145
CELA1	1990	chymotrypsin-like elastase family, member 1	multicellular organism growth	Biological process	-
FOXF1	2294	forkhead box F1	trachea development	Biological process	-
HELLS	3070	helicase, lymphoid-specific	cell division	Biological process	-
RFTN1	23180	raftlin, lipid raft linker 1	protein localization to membrane raft	Biological process	-
PRMT8	56341	protein arginine methyltransferase 8	peptidyl-arginine methylation	Biological process	16051612
CERS2	29956	ceramide synthase 2	protein binding	Molecular function	11543633
PLEKHN1	84069	pleckstrin homology domain containing, family N member 1	plasma membrane	Cellular component	-
JPH3	57338	junctophilin 3	molecular_function	Molecular function	-
ZHX2	22882	zinc fingers and homeoboxes 2	metal ion binding	Molecular function	-
PAX1	5075	paired box 1	CD4-positive, alpha-beta T cell differentiation	Biological process	-
PFKFB3	5209	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	carbohydrate metabolic process	Biological process	-
SERPINA1	5265	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1	response to hypoxia	Biological process	-
MME	4311	membrane metallo-endopeptidase	cellular response to UV-B	Biological process	20876573
THTPA	79178	thiamine triphosphatase	dephosphorylation	Biological process	11827967
EIF3G	8666	eukaryotic translation initiation factor 3, subunit G	poly(A) RNA binding	Molecular function	22658674
MAPKAP1	79109	mitogen-activated protein kinase associated protein 1	protein kinase binding	Molecular function	21177249
TRHDE	29953	thyrotropin-releasing hormone degrading enzyme	cell-cell signaling	Biological process	10491199
ADRBK2	157	adrenergic, beta, receptor kinase 2	receptor internalization	Biological process	20074556
PRKCZ	5590	protein kinase C, zeta	cell leading edge	Cellular component	-
DVL1	1855	dishevelled segment polarity protein 1	frizzled binding	Molecular function	19388021
FTO	79068	fat mass and obesity associated	DNA demethylation	Biological process	18775698
TOR1AIP2	163590	torsin A interacting protein 2	integral component of membrane	Cellular component	-
CD2	914	CD2 molecule	cell surface receptor signaling pathway	Biological process	10575274
KRT32	3882	keratin 32, type I	extracellular exosome	Cellular component	23533145
EGF	1950	epidermal growth factor	plasma membrane	Cellular component	-
KCNB1	3745	potassium channel, voltage gated Shab related subfamily B, member 1	protein homooligomerization	Biological process	-
SYNE2	23224	spectrin repeat containing, nuclear envelope 2	nuclear envelope organization	Biological process	-
KCNK6	9424	potassium channel, two pore domain subfamily K, member 6	regulation of resting membrane potential	Biological process	-
TMEM109	79073	transmembrane protein 109	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	Biological process	-
OR2L3	391192	olfactory receptor, family 2, subfamily L, member 3	plasma membrane	Cellular component	-
VPRBP	9730	Vpr (HIV-1) binding protein	COP9 signalosome	Cellular component	18850735
ATF3	467	activating transcription factor 3	positive regulation of transcription from RNA polymerase II promoter	Biological process	16300731
CDH5	1003	cadherin 5, type 2 (vascular endothelium)	plasma membrane	Cellular component	-
GRIN3A	116443	glutamate receptor, ionotropic, N-methyl-D-aspartate 3A	membrane	Cellular component	17997397
TMEM86B	255043	transmembrane protein 86B	alkenylglycerophosphoethanolamine hydrolase activity	Molecular function	21515882
UMOD	7369	uromodulin	IgG binding	Molecular function	20798515
FAT4	79633	FAT atypical cadherin 4	heart morphogenesis	Biological process	-
HEATR1	55127	HEAT repeat containing 1	positive regulation of transcription from RNA polymerase I promoter	Biological process	-
DVL1	1855	dishevelled segment polarity protein 1	negative regulation of canonical Wnt signaling pathway	Biological process	-
NVL	4931	nuclear VCP-like	nucleolus	Cellular component	-
ATG7	10533	autophagy related 7	central nervous system neuron axonogenesis	Biological process	-
AURKAIP1	54998	aurora kinase A interacting protein 1	intracellular membrane-bounded organelle	Cellular component	-
COL9A1	1297	collagen, type IX, alpha 1	collagen type IX trimer	Cellular component	9707347
SMG1	23049	SMG1 phosphatidylinositol 3-kinase-related kinase	nucleus	Cellular component	14636577
RNF14	9604	ring finger protein 14	protein binding	Molecular function	10085091
HIST1H4H	8365	histone cluster 1, H4h	small GTPase mediated signal transduction	Biological process	-
MAPK8IP1	9479	mitogen-activated protein kinase 8 interacting protein 1	regulation of transcription, DNA-templated	Biological process	-
TRAF6	7189	TNF receptor-associated factor 6, E3 ubiquitin protein ligase	myeloid dendritic cell differentiation	Biological process	-
ARHGEF7	8874	Rho guanine nucleotide exchange factor (GEF) 7	positive regulation of substrate adhesion-dependent cell spreading	Biological process	21423176
GTF2H5	404672	general transcription factor IIH, polypeptide 5	nucleolus	Cellular component	-
HOXA2	3199	homeobox A2	transcription, DNA-templated	Biological process	-
RYR2	6262	ryanodine receptor 2 (cardiac)	cellular response to epinephrine stimulus	Biological process	23507255
IGF1	3479	insulin-like growth factor 1 (somatomedin C)	negative regulation of extrinsic apoptotic signaling pathway	Biological process	16942485
TADA3	10474	transcriptional adaptor 3	regulation of tubulin deacetylation	Biological process	-
RAB40C	57799	RAB40C, member RAS oncogene family	GTPase activity	Molecular function	-
RPL10	6134	ribosomal protein L10	cytosol	Cellular component	-
GCC2	9648	GRIP and coiled-coil domain containing 2	Golgi ribbon formation	Biological process	16885419
GSK3B	2932	glycogen synthase kinase 3 beta	hypermethylation of CpG island	Biological process	-
SLC9A3R1	9368	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1	sperm midpiece	Cellular component	-
NSRP1	84081	nuclear speckle splicing regulatory protein 1	regulation of alternative mRNA splicing, via spliceosome	Biological process	21296756
CREM	1390	cAMP responsive element modulator	nucleus	Cellular component	8206879
KCNJ2	3759	potassium channel, inwardly rectifying subfamily J, member 2	Golgi apparatus	Cellular component	-
PPP1R8	5511	protein phosphatase 1, regulatory subunit 8	cell proliferation	Biological process	-
CLASP1	23332	cytoplasmic linker associated protein 1	Golgi apparatus	Cellular component	15631994
AKAP12	9590	A kinase (PRKA) anchor protein 12	focal adhesion	Cellular component	21423176
GSN	2934	gelsolin	oligodendrocyte development	Biological process	-
APOH	350	apolipoprotein H (beta-2-glycoprotein I)	heparin binding	Molecular function	-
APOBEC3A	200315	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A	nucleoplasm	Cellular component	-
FPR1	2357	formyl peptide receptor 1	phospholipase C-activating G-protein coupled receptor signaling pathway	Biological process	22859307
KCTD7	154881	potassium channel tetramerization domain containing 7	cytosol	Cellular component	-
LTC4S	4056	leukotriene C4 synthase	protein binding	Molecular function	19233132
TLR2	7097	toll-like receptor 2	cell projection	Cellular component	-
PCGF2	7703	polycomb group ring finger 2	nucleoplasm	Cellular component	-
PPOX	5498	protoporphyrinogen oxidase	mitochondrial intermembrane space	Cellular component	-
CA2	760	carbonic anhydrase II	cytosol	Cellular component	-
DBNL	28988	drebrin-like	cell junction	Cellular component	-
CCDC80	151887	coiled-coil domain containing 80	basement membrane	Cellular component	-
CIDEC	63924	cell death-inducing DFFA-like effector c	endoplasmic reticulum	Cellular component	-
TMEM74B	55321	transmembrane protein 74B	integral component of membrane	Cellular component	-
TBCC	6903	tubulin folding cofactor C	cell morphogenesis	Biological process	-
OXT	5020	oxytocin/neurophysin I prepropeptide	positive regulation of hindgut contraction	Biological process	-
DDX4	54514	DEAD (Asp-Glu-Ala-Asp) box polypeptide 4	piRNA metabolic process	Biological process	-
DNAI2	64446	dynein, axonemal, intermediate chain 2	metabolic process	Biological process	11153919
CLUAP1	23059	clusterin associated protein 1	primary cilium	Cellular component	-
ANKRD11	29123	ankyrin repeat domain 11	in utero embryonic development	Biological process	-
SYNE3	161176	spectrin repeat containing, nuclear envelope family member 3	nuclear envelope	Cellular component	21937718
SERPINB3	6317	serpin peptidase inhibitor, clade B (ovalbumin), member 3	extracellular space	Cellular component	-
RERGL	79785	RERG/RAS-like	small GTPase mediated signal transduction	Biological process	-
B4GALT7	11285	xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7	extracellular fibril organization	Biological process	16583246
DIAPH2	1730	diaphanous-related formin 2	Rho GTPase binding	Molecular function	-
ABCA7	10347	ATP-binding cassette, sub-family A (ABC1), member 7	ATP binding	Molecular function	-
LAMP3	27074	lysosomal-associated membrane protein 3	lysosomal membrane	Cellular component	-
PSME1	5720	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)	cytoplasm	Cellular component	16130169
DDX1	1653	DEAD (Asp-Glu-Ala-Asp) box helicase 1	ATP-dependent RNA helicase activity	Molecular function	-
RNF14	9604	ring finger protein 14	ubiquitin-like protein transferase activity	Molecular function	11322894
KLRD1	3824	killer cell lectin-like receptor subfamily D, member 1	innate immune response	Biological process	-
ATP2B2	491	ATPase, Ca++ transporting, plasma membrane 2	ion transmembrane transport	Biological process	-
SHH	6469	sonic hedgehog	extracellular space	Cellular component	-
PRKACA	5566	protein kinase, cAMP-dependent, catalytic, alpha	regulation of proteasomal protein catabolic process	Biological process	17565987
TRABD2B	388630	TraB domain containing 2B	extracellular exosome	Cellular component	23376485
PDE4D	5144	phosphodiesterase 4D, cAMP-specific	establishment of endothelial barrier	Biological process	-
NDST2	8509	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2	Golgi membrane	Cellular component	-
RPLP1	6176	ribosomal protein, large, P1	cytoplasm	Cellular component	-
RHEB	6009	Ras homolog enriched in brain	regulation of type B pancreatic cell development	Biological process	19258434
IK	3550	IK cytokine, down-regulator of HLA II	cell-cell signaling	Biological process	7970704
TAF5	6877	TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa	histone acetylation	Biological process	10373431
ZBTB14	7541	zinc finger and BTB domain containing 14	transcription regulatory region DNA binding	Molecular function	17714511
HNF4A	3172	hepatocyte nuclear factor 4, alpha	sequence-specific DNA binding transcription factor activity	Molecular function	10330009
GTF3C3	9330	general transcription factor IIIC, polypeptide 3, 102kDa	protein binding	Molecular function	17500595
EIF2AK4	440275	eukaryotic translation initiation factor 2 alpha kinase 4	endoplasmic reticulum unfolded protein response	Biological process	-
CD24	100133941	CD24 molecule	regulation of epithelial cell differentiation	Biological process	16930538
URM1	81605	ubiquitin related modifier 1	cytosol	Cellular component	19017811
TESC	54997	tescalcin	protein maturation	Biological process	18321853
CLRN2	645104	clarin 2	integral component of membrane	Cellular component	-
POU4F3	5459	POU class 4 homeobox 3	visual perception	Biological process	7623109
RPS20	6224	ribosomal protein S20	translational initiation	Biological process	-
GABRA6	2559	gamma-aminobutyric acid (GABA) A receptor, alpha 6	postsynaptic membrane	Cellular component	-
TRIM28	10155	tripartite motif containing 28	DNA binding	Molecular function	9016654
RPL4	6124	ribosomal protein L4	nucleus	Cellular component	-
TNFRSF19	55504	tumor necrosis factor receptor superfamily, member 19	hair follicle development	Biological process	-
TAP2	6891	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	peptide antigen-transporting ATPase activity	Molecular function	1538751
AQP2	359	aquaporin 2 (collecting duct)	membrane	Cellular component	22375059
OR2AT4	341152	olfactory receptor, family 2, subfamily AT, member 4	G-protein coupled receptor signaling pathway	Biological process	-
S100A14	57402	S100 calcium binding protein A14	response to lipopolysaccharide	Biological process	17625598
TP73	7161	tumor protein p73	response to gamma radiation	Biological process	-
STK39	27347	serine threonine kinase 39	peptidyl-serine phosphorylation	Biological process	24393035
SCX	642658	scleraxis basic helix-loop-helix transcription factor	heart valve morphogenesis	Biological process	-
CHRM5	1133	cholinergic receptor, muscarinic 5	dopamine transport	Biological process	-
ATG14	22863	autophagy related 14	activation of mitophagy in response to mitochondrial depolarization	Biological process	23878393
ROS1	6098	ROS proto-oncogene 1 , receptor tyrosine kinase	columnar/cuboidal epithelial cell development	Biological process	-
AVEN	57099	apoptosis, caspase activation inhibitor	protein binding	Molecular function	10949025
POLR2F	5435	polymerase (RNA) II (DNA directed) polypeptide F	transcription from RNA polymerase III promoter	Biological process	-
ELP2	55250	elongator acetyltransferase complex subunit 2	RNA polymerase II core binding	Molecular function	11714725
TCP1	6950	t-complex 1	translocation of peptides or proteins into host cell cytoplasm	Biological process	-
NEFH	4744	neurofilament, heavy polypeptide	axon	Cellular component	14662745
VPS39	23339	vacuolar protein sorting 39 homolog (S. cerevisiae)	intracellular protein transport	Biological process	-
ZNF208	7757	zinc finger protein 208	DNA binding	Molecular function	-
ZDHHC15	158866	zinc finger, DHHC-type containing 15	Golgi apparatus	Cellular component	16647879
CATSPERD	257062	catsper channel auxiliary subunit delta	sperm-egg recognition	Biological process	-
GALNT3	2591	polypeptide N-acetylgalactosaminyltransferase 3	O-glycan processing	Biological process	-
SMPD2	6610	sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)	ceramide biosynthetic process	Biological process	-
PHB	5245	prohibitin	cell surface	Cellular component	22417827
PLN	5350	phospholamban	endoplasmic reticulum	Cellular component	-
HAX1	10456	HCLS1 associated protein X-1	transcription factor complex	Cellular component	23001182
ITGB3	3690	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	negative regulation of lipid storage	Biological process	15215180
MSGN1	343930	mesogenin 1	somitogenesis	Biological process	-
GNA11	2767	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)	plasma membrane	Cellular component	-
KSR1	8844	kinase suppressor of ras 1	mitogen-activated protein kinase kinase binding	Molecular function	-
UPP2	151531	uridine phosphorylase 2	nucleotide catabolic process	Biological process	-
BRD7	29117	bromodomain containing 7	negative regulation of cell proliferation	Biological process	20228809
RPS15A	6210	ribosomal protein S15a	cytosolic small ribosomal subunit	Cellular component	15883184
DDIT4	54541	DNA-damage-inducible transcript 4	positive regulation of neuron death	Biological process	-
PTPRN2	5799	protein tyrosine phosphatase, receptor type, N polypeptide 2	transport vesicle membrane	Cellular component	-
AOAH	313	acyloxyacyl hydrolase (neutrophil)	acyloxyacyl hydrolase activity	Molecular function	-
AHRR	57491	aryl-hydrocarbon receptor repressor	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
IKZF1	10320	IKAROS family zinc finger 1 (Ikaros)	negative regulation of transcription, DNA-templated	Biological process	-
FGD3	89846	FYVE, RhoGEF and PH domain containing 3	positive regulation of GTPase activity	Biological process	-
OR2AK2	391191	olfactory receptor, family 2, subfamily AK, member 2	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
PLP2	5355	proteolipid protein 2 (colonic epithelium-enriched)	endoplasmic reticulum membrane	Cellular component	9124532
POU3F2	5454	POU class 3 homeobox 2	neurohypophysis development	Biological process	-
MGRN1	23295	mahogunin ring finger 1, E3 ubiquitin protein ligase	membrane	Cellular component	19946888
NLRP12	91662	NLR family, pyrin domain containing 12	regulation of interleukin-18 biosynthetic process	Biological process	12019269
OR2AG2	338755	olfactory receptor, family 2, subfamily AG, member 2	sensory perception of smell	Biological process	-
RFK	55312	riboflavin kinase	ATP binding	Molecular function	-
PELI1	57162	pellino E3 ubiquitin protein ligase 1	response to lipopolysaccharide	Biological process	-
OGG1	4968	8-oxoguanine DNA glycosylase	cellular response to cadmium ion	Biological process	-
HDGF	3068	hepatoma-derived growth factor	poly(A) RNA binding	Molecular function	22658674
SLC18A2	6571	solute carrier family 18 (vesicular monoamine transporter), member 2	response to amphetamine	Biological process	-
IKBKB	3551	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	positive regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	-
STX18	53407	syntaxin 18	endoplasmic reticulum	Cellular component	10788491
CHRM3	1131	cholinergic receptor, muscarinic 3	smooth muscle contraction	Biological process	-
AQP2	359	aquaporin 2 (collecting duct)	transport vesicle membrane	Cellular component	-
TAF5	6877	TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa	viral process	Biological process	-
KRR1	11103	KRR1, small subunit (SSU) processome component, homolog (yeast)	poly(A) RNA binding	Molecular function	22658674
ZNF284	342909	zinc finger protein 284	DNA binding	Molecular function	-
PIP	5304	prolactin-induced protein	proteolysis	Biological process	10713110
RAB11FIP5	26056	RAB11 family interacting protein 5 (class I)	recycling endosome membrane	Cellular component	-
SGPP1	81537	sphingosine-1-phosphate phosphatase 1	intrinsic apoptotic signaling pathway	Biological process	-
MAP9	79884	microtubule-associated protein 9	mitotic spindle midzone	Cellular component	-
AMHR2	269	anti-Mullerian hormone receptor, type II	anti-Mullerian hormone receptor activity	Molecular function	-
MTERF4	130916	mitochondrial transcription termination factor 4	ribosome assembly	Biological process	-
NOTCH1	4851	notch 1	astrocyte differentiation	Biological process	-
PRDX4	10549	peroxiredoxin 4	protein maturation by protein folding	Biological process	-
ARHGEF12	23365	Rho guanine nucleotide exchange factor (GEF) 12	cytoplasm	Cellular component	15755723
DAB2IP	153090	DAB2 interacting protein	positive regulation of IRE1-mediated unfolded protein response	Biological process	22013210
PCP2	126006	Purkinje cell protein 2	rhodopsin mediated signaling pathway	Biological process	-
EXD3	54932	exonuclease 3'-5' domain containing 3	metal ion binding	Molecular function	-
BCL2	596	B-cell CLL/lymphoma 2	myelin sheath	Cellular component	-
XPO1	7514	exportin 1	mitotic cell cycle	Biological process	-
CDC42	998	cell division cycle 42	substantia nigra development	Biological process	22926577
LTBP1	4052	latent transforming growth factor beta binding protein 1	transforming growth factor beta binding	Molecular function	10930463
PIK3R1	5295	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	protein phosphorylation	Biological process	-
ELAVL1	1994	ELAV like RNA binding protein 1	RNA binding	Molecular function	19561594
ATF2	1386	activating transcription factor 2	protein binding	Molecular function	10327051
INO80	54617	INO80 complex subunit	alpha-tubulin binding	Molecular function	20237820
ZFPM1	161882	zinc finger protein, FOG family member 1	T-helper cell lineage commitment	Biological process	21646796
TKT	7086	transketolase	nucleoplasm	Cellular component	-
RGMB	285704	repulsive guidance molecule family member b	endoplasmic reticulum-Golgi intermediate compartment	Cellular component	-
SPPL2C	162540	signal peptide peptidase like 2C	aspartic-type endopeptidase activity	Molecular function	-
GSK3A	2931	glycogen synthase kinase 3 alpha	cellular protein metabolic process	Biological process	-
RAB27A	5873	RAB27A, member RAS oncogene family	complement-dependent cytotoxicity	Biological process	24404184
OR8G1	26494	olfactory receptor, family 8, subfamily G, member 1 (gene/pseudogene)	sensory perception of smell	Biological process	9119360
CCDC146	57639	coiled-coil domain containing 146	protein binding	Molecular function	25416956
ZNF510	22869	zinc finger protein 510	transcription, DNA-templated	Biological process	-
CNIH4	29097	cornichon family AMPA receptor auxiliary protein 4	endoplasmic reticulum-Golgi intermediate compartment	Cellular component	24405750
LY6D	8581	lymphocyte antigen 6 complex, locus D	anchored component of membrane	Cellular component	-
ASCC1	51008	activating signal cointegrator 1 complex subunit 1	transcription factor complex	Cellular component	12077347
CYP24A1	1591	cytochrome P450, family 24, subfamily A, polypeptide 1	vitamin metabolic process	Biological process	-
ARSE	415	arylsulfatase E (chondrodysplasia punctata 1)	post-translational protein modification	Biological process	-
MR1	3140	major histocompatibility complex, class I-related	MHC class I receptor activity	Molecular function	7624800
DNAJA3	9093	DnaJ (Hsp40) homolog, subfamily A, member 3	cytoplasm	Cellular component	11679576
JUN	3725	jun proto-oncogene	positive regulation of cell differentiation	Biological process	-
NFIB	4781	nuclear factor I/B	commissural neuron axon guidance	Biological process	-
KCNB1	3745	potassium channel, voltage gated Shab related subfamily B, member 1	protein N-terminus binding	Molecular function	-
KCNA5	3741	potassium channel, voltage gated shaker related subfamily A, member 5	protein binding	Molecular function	10812072
BCL3	602	B-cell CLL/lymphoma 3	germinal center formation	Biological process	-
SLC22A4	6583	solute carrier family 22 (organic cation/zwitterion transporter), member 4	quaternary ammonium group transmembrane transporter activity	Molecular function	9426230
AGO3	192669	argonaute RISC catalytic component 3	pre-miRNA processing	Biological process	19966796
ANGPTL2	23452	angiopoietin-like 2	multicellular organismal development	Biological process	10473614
DCHS2	54798	dachsous cadherin-related 2	molecular_function	Molecular function	-
THRAP3	9967	thyroid hormone receptor associated protein 3	core promoter sequence-specific DNA binding	Molecular function	-
CGB2	114336	chorionic gonadotropin, beta polypeptide 2	extracellular region	Cellular component	-
PCNXL2	80003	pecanex-like 2 (Drosophila)	integral component of membrane	Cellular component	-
FOXI1	2299	forkhead box I1	sequence-specific DNA binding	Molecular function	-
IFNA7	3444	interferon, alpha 7	adaptive immune response	Biological process	-
ARX	170302	aristaless related homeobox	lipid digestion	Biological process	-
TRPM8	79054	transient receptor potential cation channel, subfamily M, member 8	integral component of membrane	Cellular component	-
OR5AP2	338675	olfactory receptor, family 5, subfamily AP, member 2	integral component of plasma membrane	Cellular component	-
ATP1B1	481	ATPase, Na+/K+ transporting, beta 1 polypeptide	plasma membrane	Cellular component	-
CLP1	10978	cleavage and polyadenylation factor I subunit 1	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity	Molecular function	-
TUBGCP4	27229	tubulin, gamma complex associated protein 4	microtubule	Cellular component	-
BBS10	79738	Bardet-Biedl syndrome 10	response to stimulus	Biological process	-
GPRC5A	9052	G protein-coupled receptor, class C, group 5, member A	intracellular membrane-bounded organelle	Cellular component	-
TPD52L2	7165	tumor protein D52-like 2	perinuclear region of cytoplasm	Cellular component	16112108
DUSP2	1844	dual specificity phosphatase 2	inactivation of MAPK activity	Biological process	8107850
NIPAL2	79815	NIPA-like domain containing 2	magnesium ion transmembrane transporter activity	Molecular function	-
FBL	2091	fibrillarin	histone-glutamine methyltransferase activity	Molecular function	24352239
BIN1	274	bridging integrator 1	protein binding	Molecular function	10903846
RAB32	10981	RAB32, member RAS oncogene family	membrane	Cellular component	22511774
ERCC6	2074	excision repair cross-complementation group 6	transcription from RNA polymerase II promoter	Biological process	7664335
LIMA1	51474	LIM domain and actin binding 1	focal adhesion	Cellular component	-
PPP4R2	151987	protein phosphatase 4, regulatory subunit 2	centrosome	Cellular component	10769191
DLGAP3	58512	discs, large (Drosophila) homolog-associated protein 3	beta-amyloid binding	Molecular function	-
BABAM1	29086	BRISC and BRCA1 A complex member 1	G2 DNA damage checkpoint	Biological process	19261746
VEGFB	7423	vascular endothelial growth factor B	cardiac muscle contraction	Biological process	-
EIF2B4	8890	eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa	translation	Biological process	-
WLS	79971	wntless Wnt ligand secretion mediator	mesoderm formation	Biological process	-
ZNF624	57547	zinc finger protein 624	regulation of transcription, DNA-templated	Biological process	-
IL15	3600	interleukin 15	regulation of defense response to virus by host	Biological process	-
TFAP2B	7021	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	-
ACD	65057	adrenocortical dysplasia homolog (mouse)	intracellular protein transport	Biological process	15181449
AGAP2	116986	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	protein binding	Molecular function	20075866
FBXW7	55294	F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase	SCF ubiquitin ligase complex	Cellular component	12628165
CLCN2	1181	chloride channel, voltage-sensitive 2	regulation of anion transmembrane transport	Biological process	7795595
SLC12A6	9990	solute carrier family 12 (potassium/chloride transporter), member 6	potassium ion transmembrane transporter activity	Molecular function	24393035
TH	7054	tyrosine hydroxylase	visual perception	Biological process	-
BDNF	627	brain-derived neurotrophic factor	gamma-aminobutyric acid signaling pathway	Biological process	-
CTF1	1489	cardiotrophin 1	cell proliferation	Biological process	7738033
KCNJ8	3764	potassium channel, inwardly rectifying subfamily J, member 8	sarcolemma	Cellular component	-
PRKAR2B	5577	protein kinase, cAMP-dependent, regulatory, type II, beta	cAMP-dependent protein kinase complex	Cellular component	-
IMPA2	3613	inositol(myo)-1(or 4)-monophosphatase 2	protein homodimerization activity	Molecular function	17068342
TTBK1	84630	tau tubulin kinase 1	substantia nigra development	Biological process	22926577
MLPH	79083	melanophilin	protein binding	Molecular function	12897212
TNFSF11	8600	tumor necrosis factor (ligand) superfamily, member 11	calcium ion homeostasis	Biological process	-
SBNO1	55206	strawberry notch homolog 1 (Drosophila)	biological_process	Biological process	-
CRACR2B	283229	calcium release activated channel regulator 2B	regulation of store-operated calcium entry	Biological process	-
TNFRSF1B	7133	tumor necrosis factor receptor superfamily, member 1B	ubiquitin protein ligase binding	Molecular function	11279055
TMTC3	160418	transmembrane and tetratricopeptide repeat containing 3	lung alveolus development	Biological process	-
CPS1	1373	carbamoyl-phosphate synthase 1, mitochondrial	cellular response to fibroblast growth factor stimulus	Biological process	-
JAK2	3717	Janus kinase 2	regulation of inflammatory response	Biological process	10925297
TGFBRAP1	9392	transforming growth factor, beta receptor associated protein 1	transforming growth factor beta receptor signaling pathway	Biological process	9545258
NPY5R	4889	neuropeptide Y receptor Y5	positive regulation of acute inflammatory response	Biological process	-
MAPK9	5601	mitogen-activated protein kinase 9	positive regulation of cell morphogenesis involved in differentiation	Biological process	-
TFAP2A	7020	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	negative regulation of transcription from RNA polymerase II promoter	Biological process	20066163
NCK1	4690	NCK adaptor protein 1	axon guidance	Biological process	-
ACY3	91703	aminoacylase 3	biological_process	Biological process	-
EXOC3L1	283849	exocyst complex component 3-like 1	exocytosis	Biological process	18480549
ZNF274	10782	zinc finger protein 274	cytoplasm	Cellular component	-
NR3C1	2908	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity	Molecular function	17635946
KAT5	10524	K(lysine) acetyltransferase 5	histone acetylation	Biological process	10966108
DUSP6	1848	dual specificity phosphatase 6	TRIF-dependent toll-like receptor signaling pathway	Biological process	-
TFF3	7033	trefoil factor 3 (intestinal)	extracellular exosome	Cellular component	23376485
CHRD	8646	chordin	heparin binding	Molecular function	-
SOX15	6665	SRY (sex determining region Y)-box 15	DNA binding	Molecular function	8332506
MCC	4163	mutated in colorectal cancers	negative regulation of epithelial cell proliferation	Biological process	18591935
GLYR1	84656	glyoxylate reductase 1 homolog (Arabidopsis)	oxidation-reduction process	Biological process	-
BTN3A2	11118	butyrophilin, subfamily 3, member A2	interferon-gamma secretion	Biological process	21918970
TGFB1	7040	transforming growth factor, beta 1	response to estradiol	Biological process	18039789
PPP2R5D	5528	protein phosphatase 2, regulatory subunit B', delta	protein serine/threonine phosphatase activity	Molecular function	-
ABCC6	368	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	transport	Biological process	8912525
DNAL4	10126	dynein, axonemal, light chain 4	cilium	Cellular component	-
FOXE3	2301	forkhead box E3	negative regulation of lens fiber cell differentiation	Biological process	16199865
APOLD1	81575	apolipoprotein L domain containing 1	integral component of membrane	Cellular component	-
CASP3	836	caspase 3, apoptosis-related cysteine peptidase	regulation of apoptotic DNA fragmentation	Biological process	-
NUP153	9972	nucleoporin 153kDa	viral process	Biological process	-
NUDT11	55190	nudix (nucleoside diphosphate linked moiety X)-type motif 11	inositol diphosphate tetrakisphosphate diphosphatase activity	Molecular function	-
PRKCD	5580	protein kinase C, delta	protein binding	Molecular function	10383400
ATF6B	1388	activating transcription factor 6 beta	nucleus	Cellular component	22013210
CLDN18	51208	claudin 18	integral component of membrane	Cellular component	-
BCL2L10	10017	BCL2-like 10 (apoptosis facilitator)	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	Biological process	-
SEC24C	9632	SEC24 family member C	COPII vesicle coat	Cellular component	10214955
TYRO3	7301	TYRO3 protein tyrosine kinase	protein tyrosine kinase activity	Molecular function	7537495
PTAFR	5724	platelet-activating factor receptor	G-protein coupled receptor activity	Molecular function	1322356
IL6	3569	interleukin 6	positive regulation of peptidyl-tyrosine phosphorylation	Biological process	7508917
RPS7	6201	ribosomal protein S7	ribosome	Cellular component	15883184
ADCY2	108	adenylate cyclase 2 (brain)	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway	Biological process	-
KIF4B	285643	kinesin family member 4B	ATP binding	Molecular function	-
DHFR	1719	dihydrofolate reductase	dihydrofolate reductase activity	Molecular function	6687716
CCL5	6352	chemokine (C-C motif) ligand 5	CCR1 chemokine receptor binding	Molecular function	9417081
PRKAA1	5562	protein kinase, AMP-activated, alpha 1 catalytic subunit	fatty acid oxidation	Biological process	-
STAMBP	10617	STAM binding protein	protein binding	Molecular function	10383417
ATF6	22926	activating transcription factor 6	response to stress	Biological process	10866666
TGFBR2	7048	transforming growth factor, beta receptor II (70/80kDa)	myeloid dendritic cell differentiation	Biological process	-
SLC29A3	55315	solute carrier family 29 (equilibrative nucleoside transporter), member 3	integral component of membrane	Cellular component	-
SHH	6469	sonic hedgehog	cell surface	Cellular component	-
IL4	3565	interleukin 4	microglial cell activation	Biological process	-
SH3D19	152503	SH3 domain containing 19	proline-rich region binding	Molecular function	15280379
TRIO	7204	trio Rho guanine nucleotide exchange factor	positive regulation of apoptotic process	Biological process	-
LSM4	25804	LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)	gene expression	Biological process	-
RAB12	201475	RAB12, member RAS oncogene family	Golgi membrane	Cellular component	-
POMC	5443	proopiomelanocortin	type 4 melanocortin receptor binding	Molecular function	19743876
RAPGEF3	10411	Rap guanine nucleotide exchange factor (GEF) 3	endomembrane system	Cellular component	-
COL4A4	1286	collagen, type IV, alpha 4	extracellular matrix disassembly	Biological process	-
HTR3A	3359	5-hydroxytryptamine (serotonin) receptor 3A, ionotropic	ion transmembrane transport	Biological process	-
GTF2H2C_2	730394	GTF2H2 family member C, copy 2	core TFIIH complex	Cellular component	-
MYOCD	93649	myocardin	ventricular cardiac muscle cell differentiation	Biological process	-
GXYLT1	283464	glucoside xylosyltransferase 1	Golgi membrane	Cellular component	-
PML	5371	promyelocytic leukemia	PML body organization	Biological process	17081985
GSAP	54103	gamma-secretase activating protein	beta-amyloid binding	Molecular function	20811458
AHSP	51327	alpha hemoglobin stabilizing protein	protein stabilization	Biological process	-
TP53AIP1	63970	tumor protein p53 regulated apoptosis inducing protein 1	mitochondrion	Cellular component	11030628
TLR2	7097	toll-like receptor 2	inflammatory response	Biological process	-
CXCR4	7852	chemokine (C-X-C motif) receptor 4	virus receptor activity	Molecular function	-
FGD4	121512	FYVE, RhoGEF and PH domain containing 4	metal ion binding	Molecular function	-
TCF15	6939	transcription factor 15 (basic helix-loop-helix)	neuromuscular process controlling posture	Biological process	-
MIPEP	4285	mitochondrial intermediate peptidase	mitochondrion	Cellular component	-
GUCY2D	3000	guanylate cyclase 2D, membrane (retina-specific)	receptor activity	Molecular function	1356371
CASP12	100506742	caspase 12 (gene/pseudogene)	cytoplasm	Cellular component	-
CDK11B	984	cyclin-dependent kinase 11B	mitotic nuclear division	Biological process	1639388
CHMP2B	25978	charged multivesicular body protein 2B	nucleus organization	Biological process	20616062
CRHBP	1393	corticotropin releasing hormone binding protein	cellular response to estradiol stimulus	Biological process	15345745
ACTL6B	51412	actin-like 6B	transcription, DNA-templated	Biological process	-
CCPG1	9236	cell cycle progression 1	integral component of membrane	Cellular component	-
TRH	7200	thyrotropin-releasing hormone	signal transduction	Biological process	2126343
UHRF1	29128	ubiquitin-like with PHD and ring finger domains 1	protein autoubiquitination	Biological process	17967883
TAF4	6874	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa	MLL1 complex	Cellular component	15960975
FGF16	8823	fibroblast growth factor 16	metabolic process	Biological process	9473496
SLC22A5	6584	solute carrier family 22 (organic cation/carnitine transporter), member 5	ATP binding	Molecular function	-
PAICS	10606	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase	purine nucleobase metabolic process	Biological process	-
HTT	3064	huntingtin	identical protein binding	Molecular function	22119730
SLC2A2	6514	solute carrier family 2 (facilitated glucose transporter), member 2	brush border	Cellular component	-
DGCR8	54487	DGCR8 microprocessor complex subunit	gene expression	Biological process	-
DTNBP1	84062	dystrobrevin binding protein 1	BLOC-1 complex	Cellular component	15102850
BSG	682	basigin (Ok blood group)	plasma membrane	Cellular component	-
VNN3	55350	vanin 3	anchored component of membrane	Cellular component	-
PPP1R12A	4659	protein phosphatase 1, regulatory subunit 12A	G2/M transition of mitotic cell cycle	Biological process	-
MMP13	4322	matrix metallopeptidase 13	zinc ion binding	Molecular function	23913860
ATP5G3	518	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)	mitochondrial outer membrane	Cellular component	-
KCNMB1	3779	potassium channel subfamily M regulatory beta subunit 1	detection of calcium ion	Biological process	-
PRKCE	5581	protein kinase C, epsilon	apoptotic process	Biological process	10438519
TWIST1	7291	twist family bHLH transcription factor 1	neural tube closure	Biological process	-
NTRK3	4916	neurotrophic tyrosine kinase, receptor, type 3	protein binding	Molecular function	21102451
LAPTM4B	55353	lysosomal protein transmembrane 4 beta	endomembrane system	Cellular component	-
DUSP18	150290	dual specificity phosphatase 18	MAP kinase tyrosine/serine/threonine phosphatase activity	Molecular function	-
GRPEL1	80273	GrpE-like 1, mitochondrial (E. coli)	adenyl-nucleotide exchange factor activity	Molecular function	-
BTRC	8945	beta-transducin repeat containing E3 ubiquitin protein ligase	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological process	15917222
RB1	5925	retinoblastoma 1	SWI/SNF complex	Cellular component	19149898
KAT2B	8850	K(lysine) acetyltransferase 2B	histone acetyltransferase activity	Molecular function	16829519
BCL3	602	B-cell CLL/lymphoma 3	cellular response to DNA damage stimulus	Biological process	16384933
CORO1A	11151	coronin, actin binding protein, 1A	protein homodimerization activity	Molecular function	15601263
LDB3	11155	LIM domain binding 3	muscle alpha-actinin binding	Molecular function	-
INCENP	3619	inner centromere protein antigens 135/155kDa	pericentric heterochromatin	Cellular component	9864353
FGF16	8823	fibroblast growth factor 16	extracellular space	Cellular component	9473496
NR3C1	2908	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	regulation of gluconeogenesis	Biological process	-
ABCB5	340273	ATP-binding cassette, sub-family B (MDR/TAP), member 5	cell differentiation	Biological process	-
SGPL1	8879	sphingosine-1-phosphate lyase 1	sphingolipid catabolic process	Biological process	11018465
HMGN5	79366	high mobility group nucleosome binding domain 5	transcription, DNA-templated	Biological process	-
PDHX	8050	pyruvate dehydrogenase complex, component X	protein binding	Molecular function	21516116
ITLN2	142683	intelectin 2	extracellular region	Cellular component	-
TRAT1	50852	T cell receptor associated transmembrane adaptor 1	negative regulation of transport	Biological process	11390434
CLTC	1213	clathrin, heavy chain (Hc)	extracellular vesicle	Cellular component	24769233
AP3D1	8943	adaptor-related protein complex 3, delta 1 subunit	membrane coat	Cellular component	-
BAD	572	BCL2-associated agonist of cell death	positive regulation of apoptotic process by virus	Biological process	-
SEMA3C	10512	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	post-embryonic development	Biological process	-
FGF5	2250	fibroblast growth factor 5	positive regulation of cell division	Biological process	-
CER1	9350	cerberus 1, DAN family BMP antagonist	ureteric bud development	Biological process	-
AMPD1	270	adenosine monophosphate deaminase 1	cytosol	Cellular component	-
VTA1	51534	vesicle (multivesicular body) trafficking 1	protein binding	Molecular function	15644320
ZHX1	11244	zinc fingers and homeoboxes 1	negative regulation of transcription from RNA polymerase II promoter	Biological process	17303076
B3GNT2	10678	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	axon guidance	Biological process	-
HIBCH	26275	3-hydroxyisobutyryl-CoA hydrolase	3-hydroxyisobutyryl-CoA hydrolase activity	Molecular function	8824301
EREG	2069	epiregulin	positive regulation of smooth muscle cell proliferation	Biological process	9990076
KIF20B	9585	kinesin family member 20B	WW domain binding	Molecular function	11470801
USH2A	7399	Usher syndrome 2A (autosomal recessive, mild)	hair cell differentiation	Biological process	-
AGO2	27161	argonaute RISC catalytic component 2	RISC complex	Cellular component	15260970
HOXB13	10481	homeobox B13	response to testosterone	Biological process	-
PHACTR4	65979	phosphatase and actin regulator 4	cytoplasm	Cellular component	-
NT5DC4	284958	5'-nucleotidase domain containing 4	5'-nucleotidase activity	Molecular function	-
EFR3A	23167	EFR3 homolog A (S. cerevisiae)	intracellular	Cellular component	-
SULT4A1	25830	sulfotransferase family 4A, member 1	cytosol	Cellular component	-
NEDD4L	23327	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase	ventricular cardiac muscle cell action potential	Biological process	22879586
MYO6	4646	myosin VI	perinuclear region of cytoplasm	Cellular component	-
PLK5	126520	polo-like kinase 5	protein phosphorylation	Biological process	-
HOOK2	29911	hook microtubule-tethering protein 2	protein transport	Biological process	-
RPL23	9349	ribosomal protein L23	focal adhesion	Cellular component	21423176
OXSR1	9943	oxidative stress responsive 1	stress-activated protein kinase signaling cascade	Biological process	-
ANGPT4	51378	angiopoietin 4	extracellular region	Cellular component	-
TCF12	6938	transcription factor 12	enhancer binding	Molecular function	21828274
CHST2	9435	carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2	N-acetylglucosamine 6-O-sulfotransferase activity	Molecular function	11042394
PHTF2	57157	putative homeodomain transcription factor 2	nucleus	Cellular component	-
TNFRSF1A	7132	tumor necrosis factor receptor superfamily, member 1A	cellular response to mechanical stimulus	Biological process	19593445
NCOA2	10499	nuclear receptor coactivator 2	nuclear hormone receptor binding	Molecular function	10478845
ZNF763	284390	zinc finger protein 763	transcription, DNA-templated	Biological process	-
PIK3CG	5294	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	phosphatidylinositol biosynthetic process	Biological process	-
ZNF843	283933	zinc finger protein 843	metal ion binding	Molecular function	-
EGLN2	112398	egl-9 family hypoxia-inducible factor 2	regulation of transcription from RNA polymerase II promoter in response to hypoxia	Biological process	-
MMP2	4313	matrix metallopeptidase 2	extracellular matrix organization	Biological process	-
STK11	6794	serine/threonine kinase 11	protein autophosphorylation	Biological process	11430832
NR2E3	10002	nuclear receptor subfamily 2, group E, member 3	protein binding	Molecular function	-
CAD	790	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	glutamine metabolic process	Biological process	-
FGF10	2255	fibroblast growth factor 10	Harderian gland development	Biological process	-
MMP28	79148	matrix metallopeptidase 28	zinc ion binding	Molecular function	-
LOC440434	440434	aminopeptidase puromycin sensitive pseudogene	metallopeptidase activity	Molecular function	-
LILRB5	10990	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5	cell surface receptor signaling pathway	Biological process	9548455
MGEA5	10724	meningioma expressed antigen 5 (hyaluronidase)	beta-N-acetylglucosaminidase activity	Molecular function	11148210
STRA6	64220	stimulated by retinoic acid 6	learning	Biological process	17273977
NUDT10	170685	nudix (nucleoside diphosphate linked moiety X)-type motif 10	small molecule metabolic process	Biological process	-
PKD1L3	342372	polycystic kidney disease 1-like 3	calcium channel activity	Molecular function	-
TMEM127	55654	transmembrane protein 127	molecular_function	Molecular function	-
TM9SF1	10548	transmembrane 9 superfamily member 1	cytoplasmic vesicle	Cellular component	-
PPIA	5478	peptidylprolyl isomerase A (cyclophilin A)	viral life cycle	Biological process	-
TOX3	27324	TOX high mobility group box family member 3	negative regulation of neuron apoptotic process	Biological process	21172805
AMICA1	120425	adhesion molecule, interacts with CXADR antigen 1	neutrophil extravasation	Biological process	15800062
TPR	7175	translocated promoter region, nuclear basket protein	negative regulation of transcription from RNA polymerase II promoter	Biological process	21613532
CD36	948	CD36 molecule (thrombospondin receptor)	lipid binding	Molecular function	10772654
HOXA10	3206	homeobox A10	proximal/distal pattern formation	Biological process	-
B3GNT9	84752	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9	protein glycosylation	Biological process	-
GNB1	2782	guanine nucleotide binding protein (G protein), beta polypeptide 1	photoreceptor inner segment	Cellular component	-
SLC9A1	6548	solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1	cation-transporting ATPase complex	Cellular component	24840010
HLA-DRA	3122	major histocompatibility complex, class II, DR alpha	immune response	Biological process	6304715
CCNE1	898	cyclin E1	nucleoplasm	Cellular component	-
PGGT1B	5229	protein geranylgeranyltransferase type I, beta subunit	CAAX-protein geranylgeranyltransferase complex	Cellular component	16893176
DDX21	9188	DEAD (Asp-Glu-Ala-Asp) box helicase 21	rRNA binding	Molecular function	25470060
CRIPT	9419	cysteine-rich PDZ-binding protein	dendritic spine	Cellular component	-
RHO	6010	rhodopsin	protein binding	Molecular function	17693260
TBC1D7	51256	TBC1 domain family, member 7	cytoplasmic membrane-bounded vesicle	Cellular component	-
CLEC4F	165530	C-type lectin domain family 4, member F	glycolipid binding	Molecular function	-
PLA2G16	11145	phospholipase A2, group XVI	phospholipid metabolic process	Biological process	-
GALNT2	2590	polypeptide N-acetylgalactosaminyltransferase 2	post-translational protein modification	Biological process	-
PTK7	5754	protein tyrosine kinase 7 (inactive)	ATP binding	Molecular function	-
KIF23	9493	kinesin family member 23	metabolic process	Biological process	1406973
RPL23	9349	ribosomal protein L23	protein binding	Molecular function	16189514
GHR	2690	growth hormone receptor	protein binding	Molecular function	10502458
DLK1	8788	delta-like 1 homolog (Drosophila)	extracellular space	Cellular component	7925474
PRKCA	5578	protein kinase C, alpha	protein phosphorylation	Biological process	10770950
RAB28	9364	RAB28, member RAS oncogene family	plasma membrane	Cellular component	-
EPHA2	1969	EPH receptor A2	neural tube development	Biological process	-
PLA2G15	23659	phospholipase A2, group XV	O-acyltransferase activity	Molecular function	-
SETD3	84193	SET domain containing 3	transcription, DNA-templated	Biological process	-
VPS4A	27183	vacuolar protein sorting 4 homolog A (S. cerevisiae)	cell division	Biological process	17853893
MINA	84864	MYC induced nuclear antigen	cytoplasm	Cellular component	-
KIF2A	3796	kinesin heavy chain member 2A	cell division	Biological process	-
P2RX4	5025	purinergic receptor P2X, ligand gated ion channel, 4	cellular response to ATP	Biological process	10515189
WNT5A	7474	wingless-type MMTV integration site family, member 5A	negative regulation of fibroblast growth factor receptor signaling pathway	Biological process	-
POLR2F	5435	polymerase (RNA) II (DNA directed) polypeptide F	DNA repair	Biological process	-
NUP205	23165	nucleoporin 205kDa	cytoplasm	Cellular component	-
SOX18	54345	SRY (sex determining region Y)-box 18	cell maturation	Biological process	-
CALCA	796	calcitonin-related polypeptide alpha	cellular response to tumor necrosis factor	Biological process	-
CGB	1082	chorionic gonadotropin, beta polypeptide	signal transduction	Biological process	10468638
SDCBP2	27111	syndecan binding protein (syntenin) 2	protein homodimerization activity	Molecular function	11152476
NF2	4771	neurofibromin 2 (merlin)	cortical actin cytoskeleton	Cellular component	-
APOE	348	apolipoprotein E	phototransduction, visible light	Biological process	-
NOS3	4846	nitric oxide synthase 3 (endothelial cell)	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	Biological process	-
HIST1H1E	3008	histone cluster 1, H1e	nuclear heterochromatin	Cellular component	15911621
LCMT1	51451	leucine carboxyl methyltransferase 1	cytosol	Cellular component	-
APLP2	334	amyloid beta (A4) precursor-like protein 2	regulation of protein binding	Biological process	-
PTPN12	5782	protein tyrosine phosphatase, non-receptor type 12	protein dephosphorylation	Biological process	8454633
CXCL14	9547	chemokine (C-X-C motif) ligand 14	Golgi apparatus	Cellular component	-
ECE1	1889	endothelin converting enzyme 1	lysosomal membrane	Cellular component	17897319
XRCC4	7518	X-ray repair complementing defective repair in Chinese hamster cells 4	T cell differentiation in thymus	Biological process	-
RFX7	64864	regulatory factor X, 7	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	-
KEAP1	9817	kelch-like ECH-associated protein 1	regulation of epidermal cell differentiation	Biological process	-
FGF19	9965	fibroblast growth factor 19	positive regulation of JNK cascade	Biological process	12815072
MAP2K1	5604	mitogen-activated protein kinase kinase 1	toll-like receptor signaling pathway	Biological process	-
SLC25A11	8402	solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11	gluconeogenesis	Biological process	-
P3H1	64175	prolyl 3-hydroxylase 1	collagen fibril organization	Biological process	-
CXCL8	3576	chemokine (C-X-C motif) ligand 8	intracellular	Cellular component	11877327
C8orf44-SGK3	100533105	C8orf44-SGK3 readthrough	protein serine/threonine kinase activity	Molecular function	-
CLASP2	23122	cytoplasmic linker associated protein 2	microtubule nucleation	Biological process	17543864
RNF8	9025	ring finger protein 8, E3 ubiquitin protein ligase	chromatin binding	Molecular function	18001824
UBR1	197131	ubiquitin protein ligase E3 component n-recognin 1	cytosol	Cellular component	-
PRSS12	8492	protease, serine, 12 (neurotrypsin, motopsin)	receptor-mediated endocytosis	Biological process	-
FGD5	152273	FYVE, RhoGEF and PH domain containing 5	ruffle membrane	Cellular component	-
CDKN2B	1030	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	negative regulation of cell proliferation	Biological process	17553787
HS2ST1	9653	heparan sulfate 2-O-sulfotransferase 1	membrane	Cellular component	19946888
FHOD3	80206	formin homology 2 domain containing 3	striated muscle thin filament	Cellular component	-
TPP1	1200	tripeptidyl peptidase I	bone resorption	Biological process	8215436
SEMA4D	10507	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	regulation of dendrite morphogenesis	Biological process	19788569
HAX1	10456	HCLS1 associated protein X-1	negative regulation of apoptotic process	Biological process	17008324
RS1	6247	retinoschisin 1	extrinsic component of plasma membrane	Cellular component	-
LILRA1	11024	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1	defense response	Biological process	9548455
FFAR2	2867	free fatty acid receptor 2	G-protein coupled receptor signaling pathway	Biological process	12496283
GTPBP1	9567	GTP binding protein 1	positive regulation of mRNA catabolic process	Biological process	-
MSRA	4482	methionine sulfoxide reductase A	peptide-methionine (S)-S-oxide reductase activity	Molecular function	-
NUP50	10762	nucleoporin 50kDa	carbohydrate metabolic process	Biological process	-
NKX3-1	4824	NK3 homeobox 1	positive regulation of protein kinase activity	Biological process	20395202
ATP8A2	51761	ATPase, aminophospholipid transporter, class I, type 8A, member 2	inner ear morphogenesis	Biological process	-
ENPP3	5169	ectonucleotide pyrophosphatase/phosphodiesterase 3	nucleic acid phosphodiester bond hydrolysis	Biological process	9344668
TLR8	51311	toll-like receptor 8	positive regulation of innate immune response	Biological process	16123302
EXPH5	23086	exophilin 5	positive regulation of protein secretion	Biological process	19966785
TP53RK	112858	TP53 regulating kinase	membrane	Cellular component	-
MRAP2	112609	melanocortin 2 receptor accessory protein 2	type 5 melanocortin receptor binding	Molecular function	19329486
P2RX7	5027	purinergic receptor P2X, ligand gated ion channel, 7	terminal bouton	Cellular component	-
RAF1	5894	Raf-1 proto-oncogene, serine/threonine kinase	Fc-epsilon receptor signaling pathway	Biological process	-
CCNA1	8900	cyclin A1	microtubule cytoskeleton	Cellular component	-
PEX6	5190	peroxisomal biogenesis factor 6	protein stabilization	Biological process	8670792
OXER1	165140	oxoeicosanoid (OXE) receptor 1	plasma membrane	Cellular component	-
AVP	551	arginine vasopressin	positive regulation of peptidyl-serine phosphorylation	Biological process	18402937
EPHA5	2044	EPH receptor A5	neuronal cell body	Cellular component	10375373
NPTX1	4884	neuronal pentraxin I	cellular response to potassium ion	Biological process	-
CSN1S1	1446	casein alpha s1	transmembrane transport	Biological process	-
ZHX2	22882	zinc fingers and homeoboxes 2	negative regulation of transcription from RNA polymerase II promoter	Biological process	12741956
SLC39A6	25800	solute carrier family 39 (zinc transporter), member 6	zinc II ion transmembrane transport	Biological process	12839489
EMD	2010	emerin	nuclear membrane	Cellular component	-
TGFBR1	7046	transforming growth factor, beta receptor 1	collagen fibril organization	Biological process	-
C1QTNF8	390664	C1q and tumor necrosis factor related protein 8	collagen trimer	Cellular component	-
GAS2L1	10634	growth arrest-specific 2 like 1	cytoskeletal adaptor activity	Molecular function	-
PLB1	151056	phospholipase B1	apical plasma membrane	Cellular component	-
AGTR2	186	angiotensin II receptor, type 2	brain renin-angiotensin system	Biological process	-
INSIG1	3638	insulin induced gene 1	metabolic process	Biological process	9268630
PAK7	57144	p21 protein (Cdc42/Rac)-activated kinase 7	memory	Biological process	-
PNP	4860	purine nucleoside phosphorylase	cytoskeleton	Cellular component	-
SIM1	6492	single-minded family bHLH transcription factor 1	ureteric bud development	Biological process	-
CKB	1152	creatine kinase, brain	creatine metabolic process	Biological process	-
TMEM189	387521	transmembrane protein 189	endoplasmic reticulum membrane	Cellular component	-
NAA15	80155	N(alpha)-acetyltransferase 15, NatA auxiliary subunit	transcription, DNA-templated	Biological process	-
MAPK3	5595	mitogen-activated protein kinase 3	activation of MAPKK activity	Biological process	-
TBX1	6899	T-box 1	cellular response to retinoic acid	Biological process	-
ADCY3	109	adenylate cyclase 3	transmembrane transport	Biological process	-
SAP30L	79685	SAP30-like	DNA binding	Molecular function	-
PURG	29942	purine-rich element binding protein G	DNA binding	Molecular function	-
PVRL3	25945	poliovirus receptor-related 3	plasma membrane	Cellular component	-
TPR	7175	translocated promoter region, nuclear basket protein	nucleocytoplasmic transporter activity	Molecular function	22253824
DEPDC1	55635	DEP domain containing 1	GTPase activator activity	Molecular function	-
SPTAN1	6709	spectrin, alpha, non-erythrocytic 1	cellular component disassembly involved in execution phase of apoptosis	Biological process	-
NDE1	54820	nudE neurodevelopment protein 1	organelle organization	Biological process	-
ILK	3611	integrin-linked kinase	integrin binding	Molecular function	-
TMEM177	80775	transmembrane protein 177	integral component of membrane	Cellular component	-
GNAQ	2776	guanine nucleotide binding protein (G protein), q polypeptide	regulation of melanocyte differentiation	Biological process	-
PRKAG1	5571	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	protein kinase activity	Molecular function	17028174
KCNK12	56660	potassium channel, two pore domain subfamily K, member 12	regulation of ion transmembrane transport	Biological process	-
PTGER4	5734	prostaglandin E receptor 4 (subtype EP4)	plasma membrane	Cellular component	-
ACY3	91703	aminoacylase 3	cytosol	Cellular component	-
RHBDD3	25807	rhomboid domain containing 3	proteolysis	Biological process	-
PCDH17	27253	protocadherin 17	homophilic cell adhesion via plasma membrane adhesion molecules	Biological process	-
KIFC3	3801	kinesin family member C3	Golgi organization	Biological process	-
PICALM	8301	phosphatidylinositol binding clathrin assembly protein	positive regulation of neuron death	Biological process	23589030
WDFY4	57705	WDFY family member 4	integral component of membrane	Cellular component	-
KHDRBS2	202559	KH domain containing, RNA binding, signal transduction associated 2	poly(A) binding	Molecular function	-
HIST1H2AM	8336	histone cluster 1, H2am	protein heterodimerization activity	Molecular function	-
KCNAB1	7881	potassium channel, voltage gated subfamily A regulatory beta subunit 1	oxidation-reduction process	Biological process	-
HSH2D	84941	hematopoietic SH2 domain containing	SH3/SH2 adaptor activity	Molecular function	-
TGFBR2	7048	transforming growth factor, beta receptor II (70/80kDa)	smoothened signaling pathway	Biological process	-
MYO3A	53904	myosin IIIA	sensory perception of sound	Biological process	12032315
NOX4	50507	NADPH oxidase 4	inflammatory response	Biological process	10869423
USP2	9099	ubiquitin specific peptidase 2	negative regulation of skeletal muscle tissue development	Biological process	-
STRA8	346673	stimulated by retinoic acid 8	meiotic DNA replication checkpoint	Biological process	-
SEC31A	22872	SEC31 homolog A (S. cerevisiae)	protein binding	Molecular function	16957052
DPP8	54878	dipeptidyl-peptidase 8	cytoplasm	Cellular component	11012666
PLOD3	8985	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3	endoplasmic reticulum membrane	Cellular component	-
EPHB1	2047	EPH receptor B1	central nervous system projection neuron axonogenesis	Biological process	-
FERD3L	222894	Fer3-like bHLH transcription factor	protein dimerization activity	Molecular function	-
KCNH4	23415	potassium channel, voltage gated eag related subfamily H, member 4	potassium ion transmembrane transport	Biological process	-
KLHL42	57542	kelch-like family member 42	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological process	19261606
SCAMP5	192683	secretory carrier membrane protein 5	response to endoplasmic reticulum stress	Biological process	19240033
LGALS8	3964	lectin, galactoside-binding, soluble, 8	cytoplasm	Cellular component	-
PTPRU	10076	protein tyrosine phosphatase, receptor type, U	protein tyrosine phosphatase activity	Molecular function	16574648
HSPA1B	3304	heat shock 70kDa protein 1B	enzyme binding	Molecular function	23921388
PTPN2	5771	protein tyrosine phosphatase, non-receptor type 2	positive regulation of gluconeogenesis	Biological process	-
SLC25A5	292	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5	small molecule metabolic process	Biological process	-
RAB1B	81876	RAB1B, member RAS oncogene family	protein binding	Molecular function	15796781
NCOA1	8648	nuclear receptor coactivator 1	positive regulation of transcription, DNA-templated	Biological process	15572661
AGTR2	186	angiotensin II receptor, type 2	negative regulation of icosanoid secretion	Biological process	-
TPD52L1	7164	tumor protein D52-like 1	identical protein binding	Molecular function	9484778
UGT1A10	54575	UDP glucuronosyltransferase 1 family, polypeptide A10	cellular response to hormone stimulus	Biological process	-
EWSR1	2130	EWS RNA-binding protein 1	RNA binding	Molecular function	8084618
DEDD	9191	death effector domain containing	DNA binding	Molecular function	-
CALM3	808	calmodulin 3 (phosphorylase kinase, delta)	regulation of cytokinesis	Biological process	16760425
LRBA	987	LPS-responsive vesicle trafficking, beach and anchor containing	plasma membrane	Cellular component	-
DNAJC5	80331	DnaJ (Hsp40) homolog, subfamily C, member 5	melanosome	Cellular component	-
CCR7	1236	chemokine (C-C motif) receptor 7	positive regulation of hypersensitivity	Biological process	-
DUSP5	1847	dual specificity phosphatase 5	protein binding	Molecular function	15713638
PLK1	5347	polo-like kinase 1	mitotic nuclear envelope disassembly	Biological process	-
WNT5A	7474	wingless-type MMTV integration site family, member 5A	positive regulation of NF-kappaB transcription factor activity	Biological process	18287027
SMG9	56006	SMG9 nonsense mediated mRNA decay factor	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Biological process	-
LRP2	4036	low density lipoprotein receptor-related protein 2	protein binding	Molecular function	9773776
HTT	3064	huntingtin	lactate biosynthetic process from pyruvate	Biological process	-
PER1	5187	period circadian clock 1	histone H4 acetylation	Biological process	14645221
SMAD4	4089	SMAD family member 4	transforming growth factor beta receptor, common-partner cytoplasmic mediator activity	Molecular function	9389648
PLN	5350	phospholamban	negative regulation of catalytic activity	Biological process	12032137
GJA8	2703	gap junction protein, alpha 8, 50kDa	channel activity	Molecular function	7796604
ABCA12	26154	ATP-binding cassette, sub-family A (ABC1), member 12	cellular homeostasis	Biological process	12697999
CENPM	79019	centromere protein M	small GTPase mediated signal transduction	Biological process	-
RPS29	6235	ribosomal protein S29	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Biological process	-
ADGRL4	64123	adhesion G protein-coupled receptor L4	calcium ion binding	Molecular function	-
SYNJ1	8867	synaptojanin 1	small molecule metabolic process	Biological process	-
TIMP2	7077	TIMP metallopeptidase inhibitor 2	integrin binding	Molecular function	-
HSFX1	100506164	heat shock transcription factor family, X linked 1	sequence-specific DNA binding	Molecular function	-
PTPN4	5775	protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)	peptidyl-tyrosine dephosphorylation	Biological process	1648233
BMP4	652	bone morphogenetic protein 4	negative regulation of cell proliferation involved in heart morphogenesis	Biological process	20702560
NPTXR	23467	neuronal pentraxin receptor	integral component of membrane	Cellular component	-
CSE1L	1434	CSE1 chromosome segregation 1-like (yeast)	cytoplasm	Cellular component	-
BMP2	650	bone morphogenetic protein 2	positive regulation of osteoblast differentiation	Biological process	15254224
WFS1	7466	Wolfram syndrome 1 (wolframin)	negative regulation of type B pancreatic cell apoptotic process	Biological process	16087305
IFNA6	3443	interferon, alpha 6	innate immune response	Biological process	-
DPYSL2	1808	dihydropyrimidinase-like 2	dihydropyrimidinase activity	Molecular function	8973361
BDH1	622	3-hydroxybutyrate dehydrogenase, type 1	response to nutrient	Biological process	-
GUCY2D	3000	guanylate cyclase 2D, membrane (retina-specific)	visual perception	Biological process	-
GLRB	2743	glycine receptor, beta	ion transport	Biological process	8717357
OVOL2	58495	ovo-like zinc finger 2	negative regulation of Notch signaling pathway	Biological process	19700410
SNRPF	6636	small nuclear ribonucleoprotein polypeptide F	SMN-Sm protein complex	Cellular component	18984161
TM6SF1	53346	transmembrane 6 superfamily member 1	molecular_function	Molecular function	-
SULT1A4	445329	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4	cytoplasm	Cellular component	-
TYK2	7297	tyrosine kinase 2	cytosol	Cellular component	-
HOXA10	3206	homeobox A10	multicellular organismal development	Biological process	8972230
HAO1	54363	hydroxyacid oxidase (glycolate oxidase) 1	glycolate catabolic process	Biological process	-
WAS	7454	Wiskott-Aldrich syndrome	regulation of T cell antigen processing and presentation	Biological process	22804504
GC	2638	group-specific component (vitamin D binding protein)	lysosomal lumen	Cellular component	-
ARL4A	10124	ADP-ribosylation factor-like 4A	nucleolus	Cellular component	10980193
PRKCZ	5590	protein kinase C, zeta	filamentous actin	Cellular component	-
TIAM2	26230	T-cell lymphoma invasion and metastasis 2	cytosol	Cellular component	-
ADGRE3	84658	adhesion G protein-coupled receptor E3	G-protein coupled receptor activity	Molecular function	-
UGT1A7	54577	UDP glucuronosyltransferase 1 family, polypeptide A7	xenobiotic glucuronidation	Biological process	20056724
GPAM	57678	glycerol-3-phosphate acyltransferase, mitochondrial	phospholipid metabolic process	Biological process	-
TPRA1	131601	transmembrane protein, adipocyte asscociated 1	integral component of membrane	Cellular component	-
RPS7	6201	ribosomal protein S7	membrane	Cellular component	19946888
PTGS2	5743	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	neuron projection	Cellular component	12355421
NLGN3	54413	neuroligin 3	positive regulation of excitatory postsynaptic membrane potential	Biological process	-
OCA2	4948	oculocutaneous albinism II	protein binding	Molecular function	19116314
LGI4	163175	leucine-rich repeat LGI family, member 4	adult locomotory behavior	Biological process	-
HIST1H2BK	85236	histone cluster 1, H2bk	innate immune response in mucosa	Biological process	12860195
TFF1	7031	trefoil factor 1	digestion	Biological process	9043862
SPHK1	8877	sphingosine kinase 1	negative regulation of apoptotic process	Biological process	10947957
PLA2G5	5322	phospholipase A2, group V	calcium-dependent phospholipase A2 activity	Molecular function	-
PTPRS	5802	protein tyrosine phosphatase, receptor type, S	extracellular matrix organization	Biological process	-
TFPI	7035	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)	extracellular region	Cellular component	-
ARFGEF1	10565	ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)	positive regulation of protein glycosylation in Golgi	Biological process	17227842
ALG9	79796	ALG9, alpha-1,2-mannosyltransferase	dolichol-linked oligosaccharide biosynthetic process	Biological process	-
STX2	2054	syntaxin 2	membrane raft	Cellular component	-
PRIMA1	145270	proline rich membrane anchor 1	cell junction	Cellular component	-
MTOR	2475	mechanistic target of rapamycin (serine/threonine kinase)	cellular response to hypoxia	Biological process	-
FN3K	64122	fructosamine 3 kinase	epithelial cell differentiation	Biological process	21492153
HIST1H3H	8357	histone cluster 1, H3h	negative regulation of gene expression, epigenetic	Biological process	-
ZBTB2	57621	zinc finger and BTB domain containing 2	nucleus	Cellular component	-
RAP1A	5906	RAP1A, member of RAS oncogene family	cell junction	Cellular component	-
USP26	83844	ubiquitin specific peptidase 26	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological process	-
MS4A2	2206	membrane-spanning 4-domains, subfamily A, member 2	cytokine secretion	Biological process	-
DEGS1	8560	delta(4)-desaturase, sphingolipid 1	unsaturated fatty acid biosynthetic process	Biological process	9188692
AGO2	27161	argonaute RISC catalytic component 2	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	Biological process	-
TF	7018	transferrin	extracellular exosome	Cellular component	19056867
FZD5	7855	frizzled class receptor 5	regulation of bicellular tight junction assembly	Biological process	-
PTPN20	26095	protein tyrosine phosphatase, non-receptor type 20	peptidyl-tyrosine dephosphorylation	Biological process	-
SLC25A13	10165	solute carrier family 25 (aspartate/glutamate carrier), member 13	malate-aspartate shuttle	Biological process	11566871
PSME2	5721	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)	protein polyubiquitination	Biological process	-
ZW10	9183	zw10 kinetochore protein	protein complex assembly	Biological process	11146660
Sep-02	4735	septin 2	regulation of L-glutamate transport	Biological process	-
TRAF3	7187	TNF receptor-associated factor 3	mitochondrion	Cellular component	-
COMMD1	150684	copper metabolism (Murr1) domain containing 1	copper ion homeostasis	Biological process	14685266
SPATA13	221178	spermatogenesis associated 13	regulation of cell migration	Biological process	17599059
LGR6	59352	leucine-rich repeat containing G protein-coupled receptor 6	Wnt signaling pathway	Biological process	-
EPAS1	2034	endothelial PAS domain protein 1	embryonic placenta development	Biological process	-
GPBP1L1	60313	GC-rich promoter binding protein 1-like 1	positive regulation of transcription, DNA-templated	Biological process	-
SENP2	59343	SUMO1/sentrin/SMT3 specific peptidase 2	SUMO-specific protease activity	Molecular function	11896061
RAB29	8934	RAB29, member RAS oncogene family	extracellular exosome	Cellular component	19056867
RPS6KA1	6195	ribosomal protein S6 kinase, 90kDa, polypeptide 1	toll-like receptor TLR1:TLR2 signaling pathway	Biological process	-
KIT	3815	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	hemopoiesis	Biological process	16129412
KLRD1	3824	killer cell lectin-like receptor subfamily D, member 1	transmembrane signaling receptor activity	Molecular function	7589107
NLGN4Y	22829	neuroligin 4, Y-linked	protein binding	Molecular function	17292328
ADORA1	134	adenosine A1 receptor	phagocytosis	Biological process	8360491
CDKN2A	1029	cyclin-dependent kinase inhibitor 2A	senescence-associated heterochromatin focus assembly	Biological process	16901784
ABCC5	10057	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	organic anion transmembrane transporter activity	Molecular function	-
ASPRV1	151516	aspartic peptidase, retroviral-like 1	integral component of membrane	Cellular component	16098038
SLC10A1	6554	solute carrier family 10 (sodium/bile acid cotransporter), member 1	plasma membrane	Cellular component	-
RELA	5970	v-rel avian reticuloendotheliosis viral oncogene homolog A	toll-like receptor 10 signaling pathway	Biological process	-
MAPK8	5599	mitogen-activated protein kinase 8	cellular response to lipopolysaccharide	Biological process	23776175
FZR1	51343	fizzy/cell division cycle 20 related 1 (Drosophila)	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition	Biological process	-
PRKAB1	5564	protein kinase, AMP-activated, beta 1 non-catalytic subunit	organelle organization	Biological process	-
IRAK2	3656	interleukin-1 receptor-associated kinase 2	negative regulation of NF-kappaB transcription factor activity	Biological process	10383454
BIRC2	329	baculoviral IAP repeat containing 2	response to hypoxia	Biological process	-
HOXB2	3212	homeobox B2	multicellular organismal development	Biological process	7876223
ADH1A	124	alcohol dehydrogenase 1A (class I), alpha polypeptide	alcohol dehydrogenase (NAD) activity	Molecular function	-
SEMA6D	80031	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	plasma membrane	Cellular component	-
ZNF302	55900	zinc finger protein 302	sequence-specific DNA binding transcription factor activity	Molecular function	-
RDH11	51109	retinol dehydrogenase 11 (all-trans/9-cis/11-cis)	retinol metabolic process	Biological process	-
FNDC5	252995	fibronectin type III domain containing 5	response to muscle activity	Biological process	-
ALKBH1	8846	alkB, alkylation repair homolog 1 (E. coli)	negative regulation of neuron apoptotic process	Biological process	-
EGLN3	112399	egl-9 family hypoxia-inducible factor 3	activation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	20978507
BLOC1S1	2647	biogenesis of lysosomal organelles complex-1, subunit 1	peptidyl-lysine acetylation	Biological process	22309213
BAK1	578	BCL2-antagonist/killer 1	positive regulation of proteolysis	Biological process	18387192
FOXE3	2301	forkhead box E3	sequence-specific DNA binding	Molecular function	11980846
MC4R	4160	melanocortin 4 receptor	integral component of membrane	Cellular component	-
INPP5D	3635	inositol polyphosphate-5-phosphatase, 145kDa	determination of adult lifespan	Biological process	-
JADE1	79960	jade family PHD finger 1	chromatin organization	Biological process	-
PRUNE2	158471	prune homolog 2 (Drosophila)	apoptotic process	Biological process	-
PMF1	11243	polyamine-modulated factor 1	protein binding	Molecular function	15371340
VEZF1	7716	vascular endothelial zinc finger 1	DNA binding	Molecular function	-
TRIM39	56658	tripartite motif containing 39	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	19100260
WNT2	7472	wingless-type MMTV integration site family member 2	positive regulation of canonical Wnt signaling pathway	Biological process	17948129
EPHB1	2047	EPH receptor B1	angiogenesis	Biological process	9499402
DUOX1	53905	dual oxidase 1	hydrogen peroxide biosynthetic process	Biological process	10806195
FAN1	22909	FANCD2/FANCI-associated nuclease 1	protein binding	Molecular function	20603015
LHX8	431707	LIM homeobox 8	odontogenesis of dentin-containing tooth	Biological process	-
SH3D19	152503	SH3 domain containing 19	cytosol	Cellular component	-
ARHGAP35	2909	Rho GTPase activating protein 35	negative regulation of Rho protein signal transduction	Biological process	-
HLA-DPA1	3113	major histocompatibility complex, class II, DP alpha 1	trans-Golgi network membrane	Cellular component	-
RGS9	8787	regulator of G-protein signaling 9	positive regulation of GTPase activity	Biological process	-
FXN	2395	frataxin	positive regulation of lyase activity	Biological process	18160053
TRAF3IP2	10758	TRAF3 interacting protein 2	humoral immune response	Biological process	-
TNFAIP3	7128	tumor necrosis factor, alpha-induced protein 3	negative regulation of chronic inflammatory response	Biological process	-
F2RL1	2150	coagulation factor II (thrombin) receptor-like 1	Golgi apparatus	Cellular component	8615752
APOBEC1	339	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	cytidine deamination	Biological process	7736571
UBE2D2	7322	ubiquitin-conjugating enzyme E2D 2	toll-like receptor 3 signaling pathway	Biological process	-
COX7C	1350	cytochrome c oxidase subunit VIIc	small molecule metabolic process	Biological process	-
TRIP13	9319	thyroid hormone receptor interactor 13	oogenesis	Biological process	-
TGFBR2	7048	transforming growth factor, beta receptor II (70/80kDa)	protein phosphorylation	Biological process	12015308
CEP126	57562	centrosomal protein 126kDa	centrosome	Cellular component	24867236
TYK2	7297	tyrosine kinase 2	extrinsic component of cytoplasmic side of plasma membrane	Cellular component	-
WDR1	9948	WD repeat domain 1	actin binding	Molecular function	-
PPAPDC3	84814	phosphatidic acid phosphatase type 2 domain containing 3	nuclear envelope	Cellular component	-
ZNF267	10308	zinc finger protein 267	sequence-specific DNA binding transcription factor activity	Molecular function	-
NRP2	8828	neuropilin 2	growth factor binding	Molecular function	21245381
RAB30	27314	RAB30, member RAS oncogene family	membrane	Cellular component	-
ST6GALNAC4	27090	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4	O-glycan processing	Biological process	-
LSS	4047	lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)	lanosterol synthase activity	Molecular function	-
ATIC	471	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	nucleoside metabolic process	Biological process	-
PRDM14	63978	PR domain containing 14	negative regulation of fibroblast growth factor receptor signaling pathway	Biological process	-
ICOS	29851	inducible T-cell co-stimulator	T cell tolerance induction	Biological process	-
ADRA2B	151	adrenoceptor alpha 2B	activation of MAPK activity by adrenergic receptor signaling pathway	Biological process	17215105
ATP6V0D1	9114	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1	interaction with host	Biological process	-
LUZP4	51213	leucine zipper protein 4	single-stranded RNA binding	Molecular function	25662211
FAM104A	84923	family with sequence similarity 104, member A	protein binding	Molecular function	25416956
RSPO2	340419	R-spondin 2	G-protein coupled receptor binding	Molecular function	-
SMAD3	4088	SMAD family member 3	response to hypoxia	Biological process	12411310
MIS18BP1	55320	MIS18 binding protein 1	DNA binding	Molecular function	-
WIPF3	644150	WAS/WASL interacting protein family, member 3	multicellular organismal development	Biological process	-
RYK	6259	receptor-like tyrosine kinase	protein binding	Molecular function	15454084
IRAK4	51135	interleukin-1 receptor-associated kinase 4	toll-like receptor 4 signaling pathway	Biological process	-
ATP6V1D	51382	ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D	protein binding	Molecular function	18752060
CNTFR	1271	ciliary neurotrophic factor receptor	ciliary neurotrophic factor-mediated signaling pathway	Biological process	12643274
DAB2IP	153090	DAB2 interacting protein	protein kinase binding	Molecular function	20080667
MAP2K3	5606	mitogen-activated protein kinase kinase 3	toll-like receptor 5 signaling pathway	Biological process	-
FCER1G	2207	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	neutrophil activation involved in immune response	Biological process	-
GARS	2617	glycyl-tRNA synthetase	gene expression	Biological process	-
DAGLA	747	diacylglycerol lipase, alpha	neuroblast proliferation	Biological process	-
ACTB	60	actin, beta	Fc-gamma receptor signaling pathway involved in phagocytosis	Biological process	-
PAK1	5058	p21 protein (Cdc42/Rac)-activated kinase 1	positive regulation of intracellular estrogen receptor signaling pathway	Biological process	16278681
IRF5	3663	interferon regulatory factor 5	nucleus	Cellular component	22412986
HRAS	3265	Harvey rat sarcoma viral oncogene homolog	nucleus	Cellular component	-
TMEM194B	100131211	transmembrane protein 194B	integral component of membrane	Cellular component	-
INTS10	55174	integrator complex subunit 10	integrator complex	Cellular component	16239144
CLDN6	9074	claudin 6	structural molecule activity	Molecular function	-
IL12A	3592	interleukin 12A	interleukin-27 binding	Molecular function	9342359
BBS7	55212	Bardet-Biedl syndrome 7	RNA polymerase II repressing transcription factor binding	Molecular function	22302990
MYC	4609	v-myc avian myelocytomatosis viral oncogene homolog	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	10723141
ZNF488	118738	zinc finger protein 488	oligodendrocyte development	Biological process	-
SHANK3	85358	SH3 and multiple ankyrin repeat domains 3	dendritic spine morphogenesis	Biological process	-
PPIG	9360	peptidylprolyl isomerase G (cyclophilin G)	nucleoplasm	Cellular component	-
VCP	7415	valosin containing protein	extracellular exosome	Cellular component	19056867
CLIC1	1192	chloride intracellular channel 1	chloride channel activity	Molecular function	9139710
CARTPT	9607	CART prepropeptide	extracellular space	Cellular component	-
CIART	148523	circadian associated repressor of transcription	PML body	Cellular component	-
TNNC1	7134	troponin C type 1 (slow)	response to metal ion	Biological process	-
RAB5B	5869	RAB5B, member RAS oncogene family	melanosome	Cellular component	-
SOX9	6662	SRY (sex determining region Y)-box 9	negative regulation of chondrocyte differentiation	Biological process	-
FZD3	7976	frizzled class receptor 3	dendrite	Cellular component	-
ACR	49	acrosin	protein binding	Molecular function	15950651
HM13	81502	histocompatibility (minor) 13	aspartic endopeptidase activity, intramembrane cleaving	Molecular function	16873890
AQP9	366	aquaporin 9	response to organic substance	Biological process	9733774
MXD3	83463	MAX dimerization protein 3	DNA binding	Molecular function	-
HIST2H4B	554313	histone cluster 2, H4b	CENP-A containing nucleosome assembly	Biological process	-
PTGDS	5730	prostaglandin D2 synthase 21kDa (brain)	extracellular space	Cellular component	19878301
CCR7	1236	chemokine (C-C motif) receptor 7	integral component of membrane	Cellular component	-
TAOK2	9344	TAO kinase 2	cytoplasmic vesicle membrane	Cellular component	-
FBF1	85302	Fas (TNFRSF6) binding factor 1	apical junction complex	Cellular component	18838552
RCC2	55920	regulator of chromosome condensation 2	protein domain specific binding	Molecular function	25074804
CHAF1B	8208	chromatin assembly factor 1, subunit B (p60)	positive regulation of defense response to virus by host	Biological process	22020285
DBH	1621	dopamine beta-hydroxylase (dopamine beta-monooxygenase)	dopamine catabolic process	Biological process	-
SMC3	9126	structural maintenance of chromosomes 3	stem cell maintenance	Biological process	-
PARK2	5071	parkin RBR E3 ubiquitin protein ligase	regulation of protein ubiquitination	Biological process	20871098
IKZF1	10320	IKAROS family zinc finger 1 (Ikaros)	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
CPS1	1373	carbamoyl-phosphate synthase 1, mitochondrial	cellular response to oleic acid	Biological process	-
SMARCD3	6604	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3	receptor binding	Molecular function	14701856
CREBZF	58487	CREB/ATF bZIP transcription factor	sequence-specific DNA binding transcription factor activity	Molecular function	-
EEFSEC	60678	eukaryotic elongation factor, selenocysteine-tRNA-specific	GTPase activity	Molecular function	-
C4BPA	722	complement component 4 binding protein, alpha	complement activation, classical pathway	Biological process	-
AQP1	358	aquaporin 1 (Colton blood group)	cellular response to salt stress	Biological process	18509662
TNFRSF18	8784	tumor necrosis factor receptor superfamily, member 18	negative regulation of apoptotic process	Biological process	10074428
TAS2R14	50840	taste receptor, type 2, member 14	integral component of membrane	Cellular component	16720576
WT1	7490	Wilms tumor 1	cellular response to gonadotropin stimulus	Biological process	15961562
TRAPPC1	58485	trafficking protein particle complex 1	endoplasmic reticulum	Cellular component	-
STXBP3	6814	syntaxin binding protein 3	protein to membrane docking	Biological process	-
SCN1B	6324	sodium channel, voltage gated, type I beta subunit	cardiac muscle contraction	Biological process	19808477
FEZF2	55079	FEZ family zinc finger 2	regulation of transcription from RNA polymerase II promoter	Biological process	-
HNRNPA3	220988	heterogeneous nuclear ribonucleoprotein A3	nucleoplasm	Cellular component	-
MAP3K7	6885	mitogen-activated protein kinase kinase kinase 7	protein serine/threonine kinase activity	Molecular function	-
FAP	2191	fibroblast activation protein, alpha	proteolysis	Biological process	10455171
RAE1	8480	ribonucleic acid export 1	carbohydrate metabolic process	Biological process	-
SUN2	25777	Sad1 and UNC84 domain containing 2	protein binding	Molecular function	18396275
ACKR2	1238	atypical chemokine receptor 2	immune response	Biological process	9364936
PLXNA1	5361	plexin A1	cytoplasm	Cellular component	-
ZNF682	91120	zinc finger protein 682	DNA binding	Molecular function	-
PPP1R13B	23368	protein phosphatase 1, regulatory subunit 13B	negative regulation of cell cycle	Biological process	14729977
PIK3CA	5290	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	phosphatidylinositol 3-kinase activity	Molecular function	19200708
IVL	3713	involucrin	structural molecule activity	Molecular function	10908733
TBRG4	9238	transforming growth factor beta regulator 4	mitochondrion	Cellular component	-
CRYAB	1410	crystallin, alpha B	response to hypoxia	Biological process	-
LPA	4018	lipoprotein, Lp(a)	trophoblast giant cell differentiation	Biological process	-
ADORA2A	135	adenosine A2a receptor	neuron projection morphogenesis	Biological process	-
RAD23A	5886	RAD23 homolog A (S. cerevisiae)	nucleotide-excision repair	Biological process	9372924
IGLC3	3539	immunoglobulin lambda constant 3 (Kern-Oz+ marker)	plasma membrane	Cellular component	-
ARHGAP29	9411	Rho GTPase activating protein 29	metal ion binding	Molecular function	-
CATSPER4	378807	cation channel, sperm associated 4	sperm motility	Biological process	-
TTLL8	164714	tubulin tyrosine ligase-like family member 8	protein-glycine ligase activity, initiating	Molecular function	-
ZFAT	57623	zinc finger and AT hook domain containing	cytosol	Cellular component	-
ERAP2	64167	endoplasmic reticulum aminopeptidase 2	antigen processing and presentation of peptide antigen via MHC class I	Biological process	-
POLA1	5422	polymerase (DNA directed), alpha 1, catalytic subunit	4 iron, 4 sulfur cluster binding	Molecular function	-
C1GALT1	56913	core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1	kidney development	Biological process	17228361
GAPDH	2597	glyceraldehyde-3-phosphate dehydrogenase	oxidation-reduction process	Biological process	-
FFAR1	2864	free fatty acid receptor 1	small molecule metabolic process	Biological process	-
SH3KBP1	30011	SH3-domain kinase binding protein 1	cytoskeleton	Cellular component	-
ZNF648	127665	zinc finger protein 648	regulation of transcription, DNA-templated	Biological process	-
SLC39A13	91252	solute carrier family 39 (zinc transporter), member 13	integral component of membrane	Cellular component	21917916
ARRDC3	57561	arrestin domain containing 3	negative regulation of heat generation	Biological process	-
TRIM67	440730	tripartite motif containing 67	zinc ion binding	Molecular function	-
C1QBP	708	complement component 1, q subcomponent binding protein	adrenergic receptor binding	Molecular function	-
MTR	4548	5-methyltetrahydrofolate-homocysteine methyltransferase	vitamin metabolic process	Biological process	-
FAP	2191	fibroblast activation protein, alpha	plasma membrane	Cellular component	10455171
ANXA13	312	annexin A13	extracellular exosome	Cellular component	19056867
AGRN	375790	agrin	acetylcholine receptor regulator activity	Molecular function	-
RBPMS	11030	RNA binding protein with multiple splicing	positive regulation of SMAD protein import into nucleus	Biological process	17099224
FKBP2	2286	FK506 binding protein 2, 13kDa	protein peptidyl-prolyl isomerization	Biological process	-
KDM4A	9682	lysine (K)-specific demethylase 4A	negative regulation of transcription, DNA-templated	Biological process	16024779
PELO	53918	pelota homolog (Drosophila)	cell cycle	Biological process	-
TXK	7294	TXK tyrosine kinase	protein autophosphorylation	Biological process	12081135
ISG20	3669	interferon stimulated exonuclease gene 20kDa	cell proliferation	Biological process	9569007
CPLX3	594855	complexin 3	insulin secretion	Biological process	-
PDGFRA	5156	platelet-derived growth factor receptor, alpha polypeptide	regulation of actin cytoskeleton reorganization	Biological process	10734113
HCLS1	3059	hematopoietic cell-specific Lyn substrate 1	cytoplasm	Cellular component	-
ZNF79	7633	zinc finger protein 79	regulation of transcription, DNA-templated	Biological process	-
ESD	2098	esterase D	S-formylglutathione hydrolase activity	Molecular function	-
PDK4	5166	pyruvate dehydrogenase kinase, isozyme 4	protein kinase activity	Molecular function	18658136
FAM213B	127281	family with sequence similarity 213, member B	cyclooxygenase pathway	Biological process	-
REEP2	51308	receptor accessory protein 2	endoplasmic reticulum tubular network organization	Biological process	24388663
NLRC5	84166	NLR family, CARD domain containing 5	RNA polymerase II core promoter sequence-specific DNA binding	Molecular function	20639463
PPWD1	23398	peptidylprolyl isomerase domain and WD repeat containing 1	protein peptidyl-prolyl isomerization	Biological process	-
ARL4D	379	ADP-ribosylation factor-like 4D	protein binding	Molecular function	17398095
FARP2	9855	FERM, RhoGEF and pleckstrin domain protein 2	cytoskeletal protein binding	Molecular function	-
LHX1	3975	LIM homeobox 1	nephric duct morphogenesis	Biological process	-
RPS27	6232	ribosomal protein S27	zinc ion binding	Molecular function	8407955
RAI1	10743	retinoic acid induced 1	protein binding	Molecular function	16189514
RPL41	6171	ribosomal protein L41	viral transcription	Biological process	-
IPO13	9670	importin 13	protein import into nucleus	Biological process	15964792
GUCA1C	9626	guanylate cyclase activator 1C	photoreceptor disc membrane	Cellular component	-
LIPT1	51601	lipoyltransferase 1	transferase activity, transferring acyl groups	Molecular function	-
VPS54	51542	vacuolar protein sorting 54 homolog (S. cerevisiae)	Golgi to vacuole transport	Biological process	-
TMED4	222068	transmembrane emp24 protein transport domain containing 4	signal transduction	Biological process	12761501
ARRB2	409	arrestin, beta 2	enzyme binding	Molecular function	23382074
IL17RE	132014	interleukin 17 receptor E	cytoplasm	Cellular component	-
VDR	7421	vitamin D (1,25- dihydroxyvitamin D3) receptor	regulation of calcidiol 1-monooxygenase activity	Biological process	-
IWS1	55677	IWS1 homolog (S. cerevisiae)	DNA binding	Molecular function	-
INHBA	3624	inhibin, beta A	erythrocyte differentiation	Biological process	1310063
GAL3ST4	79690	galactose-3-O-sulfotransferase 4	sulfur compound metabolic process	Biological process	11333265
CYP2B6	1555	cytochrome P450, family 2, subfamily B, polypeptide 6	arachidonic acid epoxygenase activity	Molecular function	-
FOXC2	2303	forkhead box C2	negative regulation of apoptotic process involved in outflow tract morphogenesis	Biological process	-
LRRC75A-AS1	125144	LRRC75A antisense RNA 1	mitochondrion	Cellular component	-
HRH3	11255	histamine receptor H3	negative regulation of blood pressure	Biological process	-
SCTR	6344	secretin receptor	digestion	Biological process	7612008
GAGE12B	729428	G antigen 12B	protein binding	Molecular function	25416956
ACAD11	84129	acyl-CoA dehydrogenase family, member 11	medium-chain-acyl-CoA dehydrogenase activity	Molecular function	21237683
PDE8A	5151	phosphodiesterase 8A	metal ion binding	Molecular function	-
STIM2	57620	stromal interaction molecule 2	positive regulation of calcium ion transport	Biological process	18160041
ELF1	1997	E74-like factor 1 (ets domain transcription factor)	transcription, DNA-templated	Biological process	-
EIF4ENIF1	56478	eukaryotic translation initiation factor 4E nuclear import factor 1	membrane	Cellular component	19946888
CALM1	801	calmodulin 1 (phosphorylase kinase, delta)	activation of adenylate cyclase activity	Biological process	-
INS	3630	insulin	small molecule metabolic process	Biological process	-
NRCAM	4897	neuronal cell adhesion molecule	protein binding	Molecular function	23897819
HOMER1	9456	homer scaffolding protein 1	regulation of calcium ion import	Biological process	-
SLC17A2	10246	solute carrier family 17, member 2	sodium ion transport	Biological process	9149941
NR2F6	2063	nuclear receptor subfamily 2, group F, member 6	signal transduction	Biological process	2905047
GPR173	54328	G protein-coupled receptor 173	integral component of membrane	Cellular component	-
ANGPTL3	27329	angiopoietin-like 3	lipid homeostasis	Biological process	17110602
NCDN	23154	neurochondrin	axon	Cellular component	-
ZNF70	7621	zinc finger protein 70	metal ion binding	Molecular function	-
SCN1B	6324	sodium channel, voltage gated, type I beta subunit	sodium channel inhibitor activity	Molecular function	17884088
ETFDH	2110	electron-transferring-flavoprotein dehydrogenase	respiratory electron transport chain	Biological process	-
RPS3	6188	ribosomal protein S3	apoptotic process	Biological process	-
LILRB1	10859	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	negative regulation of transforming growth factor-beta secretion	Biological process	18094328
MAGEA11	4110	melanoma antigen family A11	nucleoplasm	Cellular component	-
RAB5C	5878	RAB5C, member RAS oncogene family	metabolic process	Biological process	8646882
KCNK9	51305	potassium channel, two pore domain subfamily K, member 9	plasma membrane	Cellular component	-
LRP4	4038	low density lipoprotein receptor-related protein 4	odontogenesis of dentin-containing tooth	Biological process	-
DAB2	1601	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)	pinocytosis	Biological process	-
GLUL	2752	glutamate-ammonia ligase	cytoplasm	Cellular component	-
ATG4A	115201	autophagy related 4A, cysteine peptidase	mitochondrion degradation	Biological process	-
UBR1	197131	ubiquitin protein ligase E3 component n-recognin 1	zinc ion binding	Molecular function	-
DENND3	22898	DENN/MADD domain containing 3	endosome to lysosome transport	Biological process	-
LAMB4	22798	laminin, beta 4	basement membrane	Cellular component	-
NDUFA9	4704	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa	NADH dehydrogenase activity	Molecular function	8486360
LTBR	4055	lymphotoxin beta receptor (TNFR superfamily, member 3)	cellular response to mechanical stimulus	Biological process	19593445
IL1RL2	8808	interleukin 1 receptor-like 2	positive regulation of interleukin-6 production	Biological process	-
ATF6	22926	activating transcription factor 6	Golgi apparatus	Cellular component	16236796
PLSCR3	57048	phospholipid scramblase 3	mitochondrial membrane	Cellular component	-
SLA2	84174	Src-like-adaptor 2	negative regulation of transcription from RNA polymerase II promoter	Biological process	11696592
STAT5A	6776	signal transducer and activator of transcription 5A	female pregnancy	Biological process	-
ST3GAL4	6484	ST3 beta-galactoside alpha-2,3-sialyltransferase 4	monosialoganglioside sialyltransferase activity	Molecular function	-
GPR155	151556	G protein-coupled receptor 155	cognition	Biological process	17519220
NOD2	64127	nucleotide-binding oligomerization domain containing 2	cell surface	Cellular component	16714539
BNIP3L	665	BCL2/adenovirus E1B 19kDa interacting protein 3-like	defense response to virus	Biological process	9973195
NEUROD2	4761	neuronal differentiation 2	nucleus	Cellular component	-
TNFRSF1A	7132	tumor necrosis factor receptor superfamily, member 1A	tumor necrosis factor-activated receptor activity	Molecular function	2158863
APOPT1	84334	apoptogenic 1, mitochondrial	positive regulation of release of cytochrome c from mitochondria	Biological process	-
Sep-06	23157	septin 6	viral process	Biological process	-
UGT1A10	54575	UDP glucuronosyltransferase 1 family, polypeptide A10	flavone metabolic process	Biological process	18052087
SLC1A4	6509	solute carrier family 1 (glutamate/neutral amino acid transporter), member 4	plasma membrane	Cellular component	-
HNRNPA1	3178	heterogeneous nuclear ribonucleoprotein A1	alternative mRNA splicing, via spliceosome	Biological process	-
IGSF11	152404	immunoglobulin superfamily, member 11	extracellular exosome	Cellular component	23376485
LAT2	7462	linker for activation of T cells family, member 2	innate immune response	Biological process	-
FASN	2194	fatty acid synthase	pantothenate metabolic process	Biological process	-
LRRC8C	84230	leucine rich repeat containing 8 family, member C	plasma membrane	Cellular component	-
KCNA3	3738	potassium channel, voltage gated shaker related subfamily A, member 3	integral component of membrane	Cellular component	-
RAB5A	5868	RAB5A, member RAS oncogene family	regulation of endosome size	Biological process	17562788
CHMP4B	128866	charged multivesicular body protein 4B	viral process	Biological process	-
PPP2R5D	5528	protein phosphatase 2, regulatory subunit B', delta	nucleus	Cellular component	8703017
SEMA5A	9037	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	extracellular exosome	Cellular component	23376485
HDAC2	3066	histone deacetylase 2	positive regulation of transcription, DNA-templated	Biological process	19041327
INS	3630	insulin	wound healing	Biological process	9498508
ALDH1A2	8854	aldehyde dehydrogenase 1 family, member A2	pituitary gland development	Biological process	-
SRD5A2	6716	steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)	male gonad development	Biological process	1944596
SAP30BP	29115	SAP30 binding protein	apoptotic process	Biological process	-
CXCR5	643	chemokine (C-X-C motif) receptor 5	plasma membrane	Cellular component	-
TXNDC5	81567	thioredoxin domain containing 5 (endoplasmic reticulum)	protein disulfide isomerase activity	Molecular function	-
DNAJC1	64215	DnaJ (Hsp40) homolog, subfamily C, member 1	chaperone binding	Molecular function	-
OTOGL	283310	otogelin-like	alpha-L-arabinofuranosidase activity	Molecular function	-
ZNF264	9422	zinc finger protein 264	nucleus	Cellular component	-
LILRB1	10859	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	negative regulation of dendritic cell apoptotic process	Biological process	18094328
MLLT4	4301	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	protein binding	Molecular function	17491594
CDC42	998	cell division cycle 42	nuclear migration	Biological process	-
PTPN5	84867	protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)	protein tyrosine phosphatase activity	Molecular function	7490079
EPC2	26122	enhancer of polycomb homolog 2 (Drosophila)	DNA repair	Biological process	-
IFNA2	3440	interferon, alpha 2	B cell proliferation	Biological process	-
IKBKB	3551	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	positive regulation of type I interferon production	Biological process	-
F2RL1	2150	coagulation factor II (thrombin) receptor-like 1	positive regulation of neutrophil mediated killing of gram-negative bacterium	Biological process	21501162
ITPR3	3710	inositol 1,4,5-trisphosphate receptor, type 3	nuclear outer membrane	Cellular component	-
AQP7	364	aquaporin 7	ion transmembrane transport	Biological process	-
TIA1	7072	TIA1 cytotoxic granule-associated RNA binding protein	negative regulation of translation	Biological process	-
FOS	2353	FBJ murine osteosarcoma viral oncogene homolog	SMAD protein signal transduction	Biological process	9732876
MRPS28	28957	mitochondrial ribosomal protein S28	mitochondrial translational elongation	Biological process	-
SON	6651	SON DNA binding protein	regulation of cell cycle	Biological process	21504830
CTNND1	1500	catenin (cadherin-associated protein), delta 1	cadherin binding	Molecular function	12734196
SLC39A4	55630	solute carrier family 39 (zinc transporter), member 4	apical plasma membrane	Cellular component	-
RNF20	56254	ring finger protein 20, E3 ubiquitin protein ligase	protein polyubiquitination	Biological process	19037095
SPATS2	65244	spermatogenesis associated, serine-rich 2	poly(A) RNA binding	Molecular function	22658674
PPP4C	5531	protein phosphatase 4, catalytic subunit	nucleoplasm	Cellular component	-
NEDD4L	23327	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
S100A9	6280	S100 calcium binding protein A9	defense response to fungus	Biological process	22489132
RNF4	6047	ring finger protein 4	ubiquitin-protein transferase activity	Molecular function	-
GDPD1	284161	glycerophosphodiester phosphodiesterase domain containing 1	glycerol metabolic process	Biological process	-
PSMC6	5706	proteasome (prosome, macropain) 26S subunit, ATPase, 6	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	Biological process	-
MRPL50	54534	mitochondrial ribosomal protein L50	mitochondrial translational termination	Biological process	-
RTF1	23168	Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	Wnt signaling pathway	Biological process	-
MYO1D	4642	myosin ID	protein domain specific binding	Molecular function	22284616
CD1D	912	CD1d molecule	antigen processing and presentation, exogenous lipid antigen via MHC class Ib	Biological process	-
TGFBI	7045	transforming growth factor, beta-induced, 68kDa	cell proliferation	Biological process	1388724
AP1S2	8905	adaptor-related protein complex 1, sigma 2 subunit	clathrin-coated endocytic vesicle membrane	Cellular component	-
DNMT3B	1789	DNA (cytosine-5-)-methyltransferase 3 beta	regulation of gene expression, epigenetic	Biological process	-
ARHGEF33	100271715	Rho guanine nucleotide exchange factor (GEF) 33	Rho guanyl-nucleotide exchange factor activity	Molecular function	-
FZD5	7855	frizzled class receptor 5	Wnt-activated receptor activity	Molecular function	9054360
SFRP1	6422	secreted frizzled-related protein 1	cellular response to tumor necrosis factor	Biological process	9391078
IFNL3	282617	interferon, lambda 3	regulation of T cell activation	Biological process	-
ATF3	467	activating transcription factor 3	nucleolus	Cellular component	-
FGFR2	2263	fibroblast growth factor receptor 2	fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow	Biological process	-
OGN	4969	osteoglycin	proteinaceous extracellular matrix	Cellular component	-
CRTAM	56253	cytotoxic and regulatory T cell molecule	regulation of immune response	Biological process	-
PYCARD	29108	PYD and CARD domain containing	endoplasmic reticulum	Cellular component	-
SLC7A6	9057	solute carrier family 7 (amino acid transporter light chain, y+L system), member 6	basolateral plasma membrane	Cellular component	-
VPS28	51160	vacuolar protein sorting 28 homolog (S. cerevisiae)	ESCRT I complex	Cellular component	18005716
PTX4	390667	pentraxin 4, long	extracellular region	Cellular component	-
ZBTB16	7704	zinc finger and BTB domain containing 16	DNA binding	Molecular function	9294197
PDGFRA	5156	platelet-derived growth factor receptor, alpha polypeptide	cell chemotaxis	Biological process	1646396
GLI3	2737	GLI family zinc finger 3	embryonic digestive tract morphogenesis	Biological process	-
ACMSD	130013	aminocarboxymuconate semialdehyde decarboxylase	small molecule metabolic process	Biological process	-
MRPL32	64983	mitochondrial ribosomal protein L32	translation	Biological process	11543634
CHSY3	337876	chondroitin sulfate synthase 3	glycosaminoglycan metabolic process	Biological process	-
JAG1	182	jagged 1	extracellular region	Cellular component	11427524
PTPRM	5797	protein tyrosine phosphatase, receptor type, M	homophilic cell adhesion via plasma membrane adhesion molecules	Biological process	8393854
DRD2	1813	dopamine receptor D2	axon	Cellular component	-
KIF14	9928	kinesin family member 14	regulation of neuron apoptotic process	Biological process	-
NLRC3	197358	NLR family, CARD domain containing 3	I-kappaB kinase/NF-kappaB signaling	Biological process	15705585
ARL8A	127829	ADP-ribosylation factor-like 8A	metabolic process	Biological process	15331635
PRMT6	55170	protein arginine methyltransferase 6	histone binding	Molecular function	17898714
ID2	3398	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	neuron fate commitment	Biological process	-
CREG1	8804	cellular repressor of E1A-stimulated genes 1	negative regulation of nucleic acid-templated transcription	Biological process	9710587
HSPD1	3329	heat shock 60kDa protein 1 (chaperonin)	secretory granule	Cellular component	-
KCNIP2	30819	Kv channel interacting protein 2	regulation of potassium ion transmembrane transport	Biological process	-
HGF	3082	hepatocyte growth factor (hepapoietin A; scatter factor)	proteolysis	Biological process	2531289
SLC12A3	6559	solute carrier family 12 (sodium/chloride transporter), member 3	protein binding	Molecular function	22406640
PRPF4B	8899	pre-mRNA processing factor 4B	catalytic step 2 spliceosome	Cellular component	11991638
ACTR2	10097	ARP2 actin-related protein 2 homolog (yeast)	focal adhesion	Cellular component	21423176
TAL1	6886	T-cell acute lymphocytic leukemia 1	regulation of cell proliferation	Biological process	-
HEXA	3073	hexosaminidase A (alpha polypeptide)	sphingolipid metabolic process	Biological process	-
SEC24B	10427	SEC24 family member B	ER to Golgi vesicle-mediated transport	Biological process	-
TNNC2	7125	troponin C type 2 (fast)	troponin complex	Cellular component	17194691
MUC15	143662	mucin 15, cell surface associated	post-translational protein modification	Biological process	-
CITED4	163732	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4	cytoplasm	Cellular component	-
TIRAP	114609	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	regulation of innate immune response	Biological process	19509286
FCHO2	115548	FCH domain only 2	clathrin-mediated endocytosis	Biological process	20448150
SLC22A7	10864	solute carrier family 22 (organic anion transporter), member 7	organic anion transport	Biological process	9650585
PDZD7	79955	PDZ domain containing 7	extracellular space	Cellular component	22664934
MTHFD2	10797	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase	methylenetetrahydrofolate dehydrogenase (NADP+) activity	Molecular function	8218174
PLA2G4A	5321	phospholipase A2, group IVA (cytosolic, calcium-dependent)	phosphatidylcholine acyl-chain remodeling	Biological process	-
SELP	6403	selectin P (granule membrane protein 140kDa, antigen CD62)	fucose binding	Molecular function	7680663
CXCR1	3577	chemokine (C-X-C motif) receptor 1	G-protein coupled receptor activity	Molecular function	8381837
VEGFA	7422	vascular endothelial growth factor A	artery morphogenesis	Biological process	-
HDAC6	10013	histone deacetylase 6	negative regulation of protein complex disassembly	Biological process	15916966
C1RL	51279	complement component 1, r subcomponent-like	extracellular space	Cellular component	16502470
PLA2G10	8399	phospholipase A2, group X	positive regulation of prostaglandin secretion	Biological process	18511424
HIF3A	64344	hypoxia inducible factor 3, alpha subunit	cellular response to hypoxia	Biological process	-
OR5K4	403278	olfactory receptor, family 5, subfamily K, member 4	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
CPEB2	132864	cytoplasmic polyadenylation element binding protein 2	cytoplasm	Cellular component	20639532
ICAM1	3383	intercellular adhesion molecule 1	leukocyte migration	Biological process	12082081
TMEM55B	90809	transmembrane protein 55B	integral component of membrane	Cellular component	-
SLC7A4	6545	solute carrier family 7, member 4	cellular amino acid metabolic process	Biological process	9598310
SHC1	6464	SHC (Src homology 2 domain containing) transforming protein 1	activation of MAPK activity	Biological process	14676841
HMGA2	8091	high mobility group AT-hook 2	C2H2 zinc finger domain binding	Molecular function	14645522
AGRN	375790	agrin	basal lamina	Cellular component	9405491
FOXS1	2307	forkhead box S1	sequence-specific DNA binding	Molecular function	-
EMP1	2012	epithelial membrane protein 1	cell proliferation	Biological process	8996089
KLK15	55554	kallikrein-related peptidase 15	serine-type endopeptidase activity	Molecular function	11010966
RPS17	6218	ribosomal protein S17	translational termination	Biological process	-
C11orf73	51501	chromosome 11 open reading frame 73	cytosol	Cellular component	-
GNPDA1	10007	glucosamine-6-phosphate deaminase 1	cytoplasm	Cellular component	-
DNAAF3	352909	dynein, axonemal, assembly factor 3	axonemal dynein complex assembly	Biological process	22387996
CUEDC2	79004	CUE domain containing 2	nuclear membrane	Cellular component	-
RRP7A	27341	ribosomal RNA processing 7 homolog A (S. cerevisiae)	nucleotide binding	Molecular function	-
SLC23A2	9962	solute carrier family 23 (ascorbic acid transporter), member 2	transepithelial L-ascorbic acid transport	Biological process	18417304
DNAH6	1768	dynein, axonemal, heavy chain 6	cilium or flagellum-dependent cell motility	Biological process	-
NRXN1	9378	neurexin 1	axon guidance	Biological process	1621094
LATS2	26524	large tumor suppressor kinase 2	hormone-mediated signaling pathway	Biological process	15131260
CYP3A7	1551	cytochrome P450, family 3, subfamily A, polypeptide 7	heme binding	Molecular function	-
CCNH	902	cyclin H	holo TFIIH complex	Cellular component	9852112
SEMG2	6407	semenogelin II	extracellular exosome	Cellular component	23533145
ARHGAP28	79822	Rho GTPase activating protein 28	GTPase activator activity	Molecular function	-
PLA2G3	50487	phospholipase A2, group III	lipoxygenase pathway	Biological process	-
NDUFA10	4705	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa	response to drug	Biological process	-
S100A9	6280	S100 calcium binding protein A9	extracellular space	Cellular component	16502470
PTPN2	5771	protein tyrosine phosphatase, non-receptor type 2	protein tyrosine phosphatase activity	Molecular function	11909529
ANXA1	301	annexin A1	protein binding	Molecular function	21383699
HMGB1	3146	high mobility group box 1	single-stranded DNA binding	Molecular function	-
SEMA5A	9037	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	positive regulation of angiogenesis	Biological process	-
ADD3	120	adducin 3 (gamma)	actin binding	Molecular function	-
WNK4	65266	WNK lysine deficient protein kinase 4	ion homeostasis	Biological process	23453970
CASP2	835	caspase 2, apoptosis-related cysteine peptidase	positive regulation of apoptotic signaling pathway	Biological process	-
ERP27	121506	endoplasmic reticulum protein 27	endoplasmic reticulum lumen	Cellular component	-
RPP21	79897	ribonuclease P/MRP 21kDa subunit	response to drug	Biological process	18291362
KDR	3791	kinase insert domain receptor	branching morphogenesis of an epithelial tube	Biological process	-
ANAPC11	51529	anaphase promoting complex subunit 11	cell division	Biological process	-
SRR	63826	serine racemase	L-serine ammonia-lyase activity	Molecular function	18812225
RSPH4A	345895	radial spoke head 4 homolog A (Chlamydomonas)	cytoskeleton	Cellular component	-
INSL4	3641	insulin-like 4 (placenta)	multicellular organismal development	Biological process	8702754
SLC4A2	6522	solute carrier family 4 (anion exchanger), member 2	anion transport	Biological process	3015590
HGF	3082	hepatocyte growth factor (hepapoietin A; scatter factor)	positive regulation of transcription from RNA polymerase II promoter	Biological process	22521434
PDE8A	5151	phosphodiesterase 8A	cyclic nucleotide metabolic process	Biological process	9618252
PPAT	5471	phosphoribosyl pyrophosphate amidotransferase	organ regeneration	Biological process	-
KCNE5	23630	potassium channel, voltage gated subfamily E regulatory beta subunit 5	positive regulation of potassium ion transmembrane transport	Biological process	12324418
PM20D1	148811	peptidase M20 domain containing 1	molecular_function	Molecular function	-
C6orf89	221477	chromosome 6 open reading frame 89	midbody	Cellular component	-
POR	5447	P450 (cytochrome) oxidoreductase	FMN binding	Molecular function	-
SP1	6667	Sp1 transcription factor	embryonic camera-type eye morphogenesis	Biological process	-
C6orf15	29113	chromosome 6 open reading frame 15	heparin binding	Molecular function	-
TNFSF12	8742	tumor necrosis factor (ligand) superfamily, member 12	integral component of plasma membrane	Cellular component	9560343
VEZF1	7716	vascular endothelial zinc finger 1	transcription from RNA polymerase II promoter	Biological process	8035792
IFNG	3458	interferon, gamma	cell surface receptor signaling pathway	Biological process	10477596
HSPD1	3329	heat shock 60kDa protein 1 (chaperonin)	cyclin-dependent protein kinase activating kinase holoenzyme complex	Cellular component	11445587
PLXNB1	5364	plexin B1	ossification involved in bone maturation	Biological process	-
ATP6V1C1	528	ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1	hydrogen-exporting ATPase activity, phosphorylative mechanism	Molecular function	-
SHANK2	22941	SH3 and multiple ankyrin repeat domains 2	synapse assembly	Biological process	22699620
NCAPH	23397	non-SMC condensin I complex, subunit H	mitotic cell cycle	Biological process	-
TMEM165	55858	transmembrane protein 165	regulation of lysosomal lumen pH	Biological process	23569283
BNIP3	664	BCL2/adenovirus E1B 19kDa interacting protein 3	cell death	Biological process	-
TP53	7157	tumor protein p53	mitotic cell cycle arrest	Biological process	-
ID2	3398	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	regulation of G1/S transition of mitotic cell cycle	Biological process	16311606
TRIAP1	51499	TP53 regulated inhibitor of apoptosis 1	cellular response to UV	Biological process	15735003
PDE1B	5153	phosphodiesterase 1B, calmodulin-dependent	regulation of dopamine metabolic process	Biological process	-
CD81	975	CD81 molecule	cell proliferation	Biological process	1695320
PTPN3	5774	protein tyrosine phosphatase, non-receptor type 3	regulation of membrane depolarization during action potential	Biological process	16930557
SF3A3	10946	splicing factor 3a, subunit 3, 60kDa	mRNA splicing, via spliceosome	Biological process	-
HPGDS	27306	hematopoietic prostaglandin D synthase	cytosol	Cellular component	-
LIN7C	55327	lin-7 homolog C (C. elegans)	postsynaptic membrane	Cellular component	-
HOXA2	3199	homeobox A2	dorsal/ventral pattern formation	Biological process	-
RPGRIP1L	23322	RPGRIP1-like	lateral ventricle development	Biological process	-
GOT2	2806	glutamic-oxaloacetic transaminase 2, mitochondrial	L-phenylalanine:2-oxoglutarate aminotransferase activity	Molecular function	-
DLD	1738	dihydrolipoamide dehydrogenase	flavin adenine dinucleotide binding	Molecular function	-
CBX5	23468	chromobox homolog 5	protein homodimerization activity	Molecular function	-
CTBS	1486	chitobiase, di-N-acetyl-	extracellular space	Cellular component	16502470
FOS	2353	FBJ murine osteosarcoma viral oncogene homolog	response to immobilization stress	Biological process	-
GPC6	10082	glypican 6	glycosaminoglycan catabolic process	Biological process	-
NEK6	10783	NIMA-related kinase 6	signal transducer activity	Molecular function	12761501
RAB11FIP5	26056	RAB11 family interacting protein 5 (class I)	protein binding	Molecular function	11278501
CCR8	1237	chemokine (C-C motif) receptor 8	chemokine receptor activity	Molecular function	9417093
AGBL3	340351	ATP/GTP binding protein-like 3	protein side chain deglutamylation	Biological process	25103237
ZNF582	147948	zinc finger protein 582	transcription, DNA-templated	Biological process	-
MMP20	9313	matrix metallopeptidase 20	metalloendopeptidase activity	Molecular function	9398237
CNOT10	25904	CCR4-NOT transcription complex, subunit 10	gene silencing by RNA	Biological process	-
CHMP2A	27243	charged multivesicular body protein 2A	protein binding	Molecular function	14505570
CYR61	3491	cysteine-rich, angiogenic inducer, 61	anatomical structure morphogenesis	Biological process	9135077
RIN1	9610	Ras and Rab interactor 1	plasma membrane	Cellular component	12574403
REXO2	25996	RNA exonuclease 2	3'-5'-exoribonuclease activity	Molecular function	-
SLC8A1	6546	solute carrier family 8 (sodium/calcium exchanger), member 1	sarcolemma	Cellular component	-
EVX2	344191	even-skipped homeobox 2	limb morphogenesis	Biological process	-
CD320	51293	CD320 molecule	vitamin metabolic process	Biological process	-
STK26	51765	serine/threonine protein kinase 26	signal transduction by protein phosphorylation	Biological process	-
ARHGAP11B	89839	Rho GTPase activating protein 11B	cerebral cortex development	Biological process	25721503
USP32	84669	ubiquitin specific peptidase 32	membrane	Cellular component	-
PRDX4	10549	peroxiredoxin 4	I-kappaB phosphorylation	Biological process	9388242
RPA2	6118	replication protein A2, 32kDa	regulation of DNA damage checkpoint	Biological process	21504906
MGST2	4258	microsomal glutathione S-transferase 2	small molecule metabolic process	Biological process	-
CARM1	10498	coactivator-associated arginine methyltransferase 1	protein binding	Molecular function	20111005
ASAP2	8853	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	GTPase activator activity	Molecular function	-
TMEM214	54867	transmembrane protein 214	endoplasmic reticulum membrane	Cellular component	-
WHAMM	123720	WAS protein homolog associated with actin, golgi membranes and microtubules	actin filament reorganization	Biological process	23087206
CEP170	9859	centrosomal protein 170kDa	spindle	Cellular component	-
DSTYK	25778	dual serine/threonine and tyrosine protein kinase	apical plasma membrane	Cellular component	23862974
PLAUR	5329	plasminogen activator, urokinase receptor	movement of cell or subcellular component	Biological process	1689240
IGFBP5	3488	insulin-like growth factor binding protein 5	regulation of glucose metabolic process	Biological process	-
TNFAIP3	7128	tumor necrosis factor, alpha-induced protein 3	tolerance induction to lipopolysaccharide	Biological process	21220427
MAPK8	5599	mitogen-activated protein kinase 8	positive regulation of deacetylase activity	Biological process	20027304
TNF	7124	tumor necrosis factor	tumor necrosis factor-mediated signaling pathway	Biological process	-
LZTS2	84445	leucine zipper, putative tumor suppressor 2	protein binding	Molecular function	16189514
OR52N2	390077	olfactory receptor, family 52, subfamily N, member 2	G-protein coupled receptor signaling pathway	Biological process	-
CCM2	83605	cerebral cavernous malformation 2	integrin-mediated signaling pathway	Biological process	16037064
NME1	4830	NME/NM23 nucleoside diphosphate kinase 1	membrane	Cellular component	19946888
MUC17	140453	mucin 17, cell surface associated	cellular protein metabolic process	Biological process	-
CTDSPL	10217	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like	biological_process	Biological process	-
SLC9A1	6548	solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	22688515
ACVR2A	92	activin A receptor, type IIA	positive regulation of erythrocyte differentiation	Biological process	9032295
PML	5371	promyelocytic leukemia	cytosol	Cellular component	-
DHRS2	10202	dehydrogenase/reductase (SDR family) member 2	mitochondrion	Cellular component	19443906
SOX10	6663	SRY (sex determining region Y)-box 10	positive regulation of gliogenesis	Biological process	-
GNPTAB	79158	N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits	transcription factor binding	Molecular function	-
CSNK1A1L	122011	casein kinase 1, alpha 1-like	peptidyl-serine phosphorylation	Biological process	-
PRKAG2	51422	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	gene expression	Biological process	-
IHH	3549	indian hedgehog	plasma membrane	Cellular component	21537345
UBR3	130507	ubiquitin protein ligase E3 component n-recognin 3 (putative)	integral component of membrane	Cellular component	-
ST8SIA6	338596	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6	Golgi membrane	Cellular component	-
TRIM69	140691	tripartite motif containing 69	protein ubiquitination	Biological process	-
ELL3	80237	elongation factor RNA polymerase II-like 3	nucleolus	Cellular component	-
VIMP	55829	VCP-interacting membrane selenoprotein	regulation of nitric oxide metabolic process	Biological process	18675776
DLG1	1739	discs, large homolog 1 (Drosophila)	postsynaptic membrane	Cellular component	-
GPRC5B	51704	G protein-coupled receptor, class C, group 5, member B	cell surface	Cellular component	-
NRG1	3084	neuregulin 1	membrane	Cellular component	8096067
RAB11A	8766	RAB11A, member RAS oncogene family	positive regulation of epithelial cell migration	Biological process	22613965
RPL6	6128	ribosomal protein L6	cytoplasmic ribonucleoprotein granule	Cellular component	15121898
ABCB11	8647	ATP-binding cassette, sub-family B (MDR/TAP), member 11	extracellular exosome	Cellular component	19056867
LAMB3	3914	laminin, beta 3	structural molecule activity	Molecular function	7550320
MAPK9	5601	mitogen-activated protein kinase 9	regulation of JNK cascade	Biological process	-
UHRF2	115426	ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase	DNA binding	Molecular function	-
LDB1	8861	LIM domain binding 1	positive regulation of hemoglobin biosynthetic process	Biological process	-
PF4V1	5197	platelet factor 4 variant 1	chemokine-mediated signaling pathway	Biological process	-
PLP2	5355	proteolipid protein 2 (colonic epithelium-enriched)	chemokine binding	Molecular function	15474493
G6PD	2539	glucose-6-phosphate dehydrogenase	membrane	Cellular component	19946888
TTYH1	57348	tweety family member 1	chloride channel complex	Cellular component	-
MLIP	90523	muscular LMNA-interacting protein	RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription	Molecular function	-
TPR	7175	translocated promoter region, nuclear basket protein	viral process	Biological process	-
MAP9	79884	microtubule-associated protein 9	astral microtubule	Cellular component	-
MSH2	4436	mutS homolog 2	intra-S DNA damage checkpoint	Biological process	-
RAPGEF2	9693	Rap guanine nucleotide exchange factor (GEF) 2	small GTPase mediated signal transduction	Biological process	10608883
KAT6A	7994	K(lysine) acetyltransferase 6A	aorta morphogenesis	Biological process	-
GNAI3	2773	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3	extracellular exosome	Cellular component	19056867
FYN	2534	FYN proto-oncogene, Src family tyrosine kinase	response to ethanol	Biological process	-
B3GNT5	84002	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5	intracellular	Cellular component	11384981
EDN1	1906	endothelin 1	Weibel-Palade body	Cellular component	-
PRDX5	25824	peroxiredoxin 5	apoptotic process	Biological process	18262354
KLK8	11202	kallikrein-related peptidase 8	neuron projection morphogenesis	Biological process	-
DGAT1	8694	diacylglycerol O-acyltransferase 1	2-acylglycerol O-acyltransferase activity	Molecular function	-
ACVRL1	94	activin A receptor type II-like 1	negative regulation of endothelial cell migration	Biological process	17068149
E2F7	144455	E2F transcription factor 7	negative regulation of cell proliferation	Biological process	22802528
TNFAIP1	7126	tumor necrosis factor, alpha-induced protein 1 (endothelial)	embryo development	Biological process	-
B2M	567	beta-2-microglobulin	membrane	Cellular component	19946888
NLGN4X	57502	neuroligin 4, X-linked	presynaptic membrane assembly	Biological process	19726642
FGF13	2258	fibroblast growth factor 13	dendrite	Cellular component	-
FGFRL1	53834	fibroblast growth factor receptor-like 1	diaphragm development	Biological process	-
KLF17	128209	Kruppel-like factor 17	metal ion binding	Molecular function	-
ATXN2	6311	ataxin 2	regulation of cytoplasmic mRNA processing body assembly	Biological process	-
RAB21	23011	RAB21, member RAS oncogene family	endosome	Cellular component	-
RAB11B	9230	RAB11B, member RAS oncogene family	melanosome transport	Biological process	-
GNB2	2783	guanine nucleotide binding protein (G protein), beta polypeptide 2	small molecule metabolic process	Biological process	-
FBXO18	84893	F-box protein, helicase, 18	nucleus	Cellular component	-
TMOD2	29767	tropomodulin 2 (neuronal)	myofibril assembly	Biological process	-
ZNF517	340385	zinc finger protein 517	nucleus	Cellular component	-
GAS6	2621	growth arrest-specific 6	phagocytosis	Biological process	21501828
PIGW	284098	phosphatidylinositol glycan anchor biosynthesis, class W	endoplasmic reticulum membrane	Cellular component	-
GNB1	2782	guanine nucleotide binding protein (G protein), beta polypeptide 1	dendrite	Cellular component	-
GPER1	2852	G protein-coupled estrogen receptor 1	axon	Cellular component	-
NCF1	653361	neutrophil cytosolic factor 1	neuronal cell body	Cellular component	-
ILF3	3609	interleukin enhancer binding factor 3, 90kDa	protein phosphorylation	Biological process	21123651
MAPRE1	22919	microtubule-associated protein, RP/EB family, member 1	Golgi apparatus	Cellular component	-
PRKACB	5567	protein kinase, cAMP-dependent, catalytic, beta	synaptic transmission	Biological process	-
HFE	3077	hemochromatosis	external side of plasma membrane	Cellular component	24904118
HTR1B	3351	5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled	drug binding	Molecular function	-
FAM73A	374986	family with sequence similarity 73, member A	integral component of membrane	Cellular component	-
HOXB6	3216	homeobox B6	regulation of transcription, DNA-templated	Biological process	-
FBXL3	26224	F-box and leucine-rich repeat protein 3	cytosol	Cellular component	-
RALGPS1	9649	Ral GEF with PH domain and SH3 binding motif 1	positive regulation of GTPase activity	Biological process	-
MED17	9440	mediator complex subunit 17	transcription initiation from RNA polymerase II promoter	Biological process	-
GAA	2548	glucosidase, alpha; acid	sucrose metabolic process	Biological process	9505277
DYNC1I2	1781	dynein, cytoplasmic 1, intermediate chain 2	metabolic process	Biological process	8522607
SIX4	51804	SIX homeobox 4	negative regulation of transcription, DNA-templated	Biological process	-
ZBTB32	27033	zinc finger and BTB domain containing 32	T cell proliferation	Biological process	-
SNW1	22938	SNW domain containing 1	transcription, DNA-templated	Biological process	-
LARP1	23367	La ribonucleoprotein domain family, member 1	TOR signaling	Biological process	24532714
UGT2B28	54490	UDP glucuronosyltransferase 2 family, polypeptide B28	glucuronosyltransferase activity	Molecular function	-
BMP5	653	bone morphogenetic protein 5	negative regulation of cortisol biosynthetic process	Biological process	19584291
FLT1	2321	fms-related tyrosine kinase 1	vascular endothelial growth factor receptor signaling pathway	Biological process	-
EPS8L1	54869	EPS8-like 1	Rac guanyl-nucleotide exchange factor activity	Molecular function	14565974
SLC6A7	6534	solute carrier family 6 (neurotransmitter transporter), member 7	proline transport	Biological process	7651355
TOP3A	7156	topoisomerase (DNA) III alpha	DNA topoisomerase type I activity	Molecular function	20445207
SLC8A1	6546	solute carrier family 8 (sodium/calcium exchanger), member 1	calcium ion import	Biological process	1374913
CNR2	1269	cannabinoid receptor 2 (macrophage)	plasma membrane	Cellular component	-
CAB39	51719	calcium binding protein 39	cellular hypotonic response	Biological process	24393035
TBX1	6899	T-box 1	positive regulation of mesenchymal cell proliferation	Biological process	-
CIRBP	1153	cold inducible RNA binding protein	poly(A) RNA binding	Molecular function	22658674
BIRC5	332	baculoviral IAP repeat containing 5	chaperone binding	Molecular function	18086682
SIX2	10736	SIX homeobox 2	chondrocyte differentiation	Biological process	-
STK4	6789	serine/threonine kinase 4	regulation of mitotic cell cycle	Biological process	-
TNNT3	7140	troponin T type 3 (skeletal, fast)	actin binding	Molecular function	17194691
TMEM79	84283	transmembrane protein 79	cornification	Biological process	-
MAP4K2	5871	mitogen-activated protein kinase kinase kinase kinase 2	innate immune response	Biological process	-
GLS	2744	glutaminase	cellular amino acid biosynthetic process	Biological process	-
INPP5B	3633	inositol polyphosphate-5-phosphatase, 75kDa	integral component of membrane	Cellular component	-
ZDHHC13	54503	zinc finger, DHHC-type containing 13	palmitoyltransferase activity	Molecular function	-
TLR4	7099	toll-like receptor 4	positive regulation of macrophage cytokine production	Biological process	-
SDF2L1	23753	stromal cell-derived factor 2-like 1	response to endoplasmic reticulum stress	Biological process	-
WRN	7486	Werner syndrome, RecQ helicase-like	DNA synthesis involved in DNA repair	Biological process	17563354
DNMT3B	1789	DNA (cytosine-5-)-methyltransferase 3 beta	response to drug	Biological process	-
TLCD1	116238	TLC domain containing 1	integral component of membrane	Cellular component	-
MSMO1	6307	methylsterol monooxygenase 1	integral component of membrane	Cellular component	-
NAB1	4664	NGFI-A binding protein 1 (EGR1 binding protein 1)	myelination	Biological process	-
SMARCB1	6598	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	Tat protein binding	Molecular function	16687403
SLC6A15	55117	solute carrier family 6 (neutral amino acid transporter), member 15	plasma membrane	Cellular component	-
SOX18	54345	SRY (sex determining region Y)-box 18	positive regulation of transcription from RNA polymerase II promoter	Biological process	18065521
ASIC5	51802	acid sensing (proton gated) ion channel family member 5	ion transmembrane transport	Biological process	-
PDZD11	51248	PDZ domain containing 11	transmembrane transport	Biological process	-
SMG5	23381	SMG5 nonsense mediated mRNA decay factor	mRNA export from nucleus	Biological process	16488880
SLC6A7	6534	solute carrier family 6 (neurotransmitter transporter), member 7	neurotransmitter transport	Biological process	-
THOC1	9984	THO complex 1	transcription export complex	Cellular component	15833825
ATXN1	6310	ataxin 1	identical protein binding	Molecular function	11001934
KLF11	8462	Kruppel-like factor 11	positive regulation of apoptotic process	Biological process	21171965
BUB3	9184	BUB3 mitotic checkpoint protein	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
SLC30A9	10463	solute carrier family 30 (zinc transporter), member 9	sequence-specific DNA binding transcription factor activity	Molecular function	10409434
GH1	2688	growth hormone 1	growth hormone receptor signaling pathway	Biological process	8063815
AURKB	9212	aurora kinase B	chromocenter	Cellular component	-
TSFM	10102	Ts translation elongation factor, mitochondrial	translation elongation factor activity	Molecular function	-
HIST1H3C	8352	histone cluster 1, H3c	DNA replication-dependent nucleosome assembly	Biological process	14718166
ATRIP	84126	ATR interacting protein	nucleus	Cellular component	-
SQSTM1	8878	sequestosome 1	regulation of Ras protein signal transduction	Biological process	8618896
FGF16	8823	fibroblast growth factor 16	neurotrophin TRK receptor signaling pathway	Biological process	-
CACNG4	27092	calcium channel, voltage-dependent, gamma subunit 4	alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex	Cellular component	-
ZNF385A	25946	zinc finger protein 385A	mRNA 3'-UTR binding	Molecular function	-
BCAM	4059	basal cell adhesion molecule (Lutheran blood group)	plasma membrane	Cellular component	9166867
TAX1BP1	8887	Tax1 (human T-cell leukemia virus type I) binding protein 1	metal ion binding	Molecular function	-
CACFD1	11094	calcium channel flower domain containing 1	molecular_function	Molecular function	-
LUM	4060	lumican	proteinaceous extracellular matrix	Cellular component	7665616
SNX2	6643	sorting nexin 2	membrane	Cellular component	9819414
ENTPD8	377841	ectonucleoside triphosphate diphosphohydrolase 8	integral component of membrane	Cellular component	-
PKN1	5585	protein kinase N1	plasma membrane	Cellular component	-
FSCN2	25794	fascin actin-bundling protein 2, retinal	visual perception	Biological process	10783262
HGD	3081	homogentisate 1,2-dioxygenase	extracellular exosome	Cellular component	19056867
GEM	2669	GTP binding protein overexpressed in skeletal muscle	signal transduction	Biological process	7912851
MECP2	4204	methyl CpG binding protein 2	long-term memory	Biological process	-
KCNK3	3777	potassium channel, two pore domain subfamily K, member 3	brain development	Biological process	-
USP33	23032	ubiquitin specific peptidase 33	cellular response to starvation	Biological process	24056301
TLR2	7097	toll-like receptor 2	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
NAGLU	4669	N-acetylglucosaminidase, alpha	small molecule metabolic process	Biological process	-
PVRL2	5819	poliovirus receptor-related 2 (herpesvirus entry mediator B)	coreceptor activity	Molecular function	9657005
LTA	4049	lymphotoxin alpha	positive regulation of apoptotic process	Biological process	-
AMDHD1	144193	amidohydrolase domain containing 1	histidine catabolic process to glutamate and formate	Biological process	-
ERRFI1	54206	ERBB receptor feedback inhibitor 1	negative regulation of protein autophosphorylation	Biological process	18046415
CCT2	10576	chaperonin containing TCP1, subunit 2 (beta)	'de novo' posttranslational protein folding	Biological process	-
APOD	347	apolipoprotein D	extracellular space	Cellular component	16502470
DCC	1630	DCC netrin 1 receptor	netrin receptor activity	Molecular function	-
WNT11	7481	wingless-type MMTV integration site family, member 11	canonical Wnt signaling pathway	Biological process	-
SWSAP1	126074	SWIM-type zinc finger 7 associated protein 1	Shu complex	Cellular component	21965664
RPH3AL	9501	rabphilin 3A-like (without C2 domains)	protein binding	Molecular function	25416956
OXT	5020	oxytocin/neurophysin I prepropeptide	negative regulation of blood pressure	Biological process	-
CHRNB4	1143	cholinergic receptor, nicotinic, beta 4 (neuronal)	cell junction	Cellular component	-
ATAD1	84896	ATPase family, AAA domain containing 1	ATPase activity	Molecular function	-
CIDEC	63924	cell death-inducing DFFA-like effector c	molecular_function	Molecular function	-
ATP1A2	477	ATPase, Na+/K+ transporting, alpha 2 polypeptide	regulation of respiratory gaseous exchange by neurological system process	Biological process	-
EHMT2	10919	euchromatic histone-lysine N-methyltransferase 2	nucleoplasm	Cellular component	-
WT1	7490	Wilms tumor 1	nucleolus	Cellular component	-
HCAR1	27198	hydroxycarboxylic acid receptor 1	integral component of membrane	Cellular component	-
ASPH	444	aspartate beta-hydroxylase	electron carrier activity	Molecular function	7821814
CLDN9	9080	claudin 9	integral component of membrane	Cellular component	-
POU4F1	5457	POU class 4 homeobox 1	regulation of neurogenesis	Biological process	-
ZNF280B	140883	zinc finger protein 280B	metal ion binding	Molecular function	-
MDK	4192	midkine (neurite growth-promoting factor 2)	extracellular region	Cellular component	-
ISG20	3669	interferon stimulated exonuclease gene 20kDa	RNA phosphodiester bond hydrolysis, exonucleolytic	Biological process	-
IDO2	169355	indoleamine 2,3-dioxygenase 2	tryptophan catabolic process	Biological process	-
GPR176	11245	G protein-coupled receptor 176	G-protein coupled receptor activity	Molecular function	-
STAT6	6778	signal transducer and activator of transcription 6, interleukin-4 induced	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
FLT4	2324	fms-related tyrosine kinase 4	positive regulation of endothelial cell migration	Biological process	11532940
KCNAB3	9196	potassium channel, voltage gated subfamily A regulatory beta subunit 3	regulation of ion transmembrane transport	Biological process	-
ACVRL1	94	activin A receptor type II-like 1	protein phosphorylation	Biological process	12065756
RPS6KA2	6196	ribosomal protein S6 kinase, 90kDa, polypeptide 2	peptidyl-serine phosphorylation	Biological process	-
BSG	682	basigin (Ok blood group)	melanosome	Cellular component	-
TOP2A	7153	topoisomerase (DNA) II alpha 170kDa	DNA topoisomerase type II (ATP-hydrolyzing) activity	Molecular function	16611985
GABRB2	2561	gamma-aminobutyric acid (GABA) A receptor, beta 2	cytosol	Cellular component	-
SSTR2	6752	somatostatin receptor 2	spermatogenesis	Biological process	-
ADAR	103	adenosine deaminase, RNA-specific	nucleoplasm	Cellular component	-
UNC5CL	222643	unc-5 homolog C (C. elegans)-like	positive regulation of JNK cascade	Biological process	22158417
GLI3	2737	GLI family zinc finger 3	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	2118997
POLL	27343	polymerase (DNA directed), lambda	metal ion binding	Molecular function	-
SMARCAD1	56916	SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1	site of double-strand break	Cellular component	22960744
C1QL3	389941	complement component 1, q subcomponent-like 3	extracellular region	Cellular component	-
RELA	5970	v-rel avian reticuloendotheliosis viral oncogene homolog A	cellular response to lipopolysaccharide	Biological process	-
NACA2	342538	nascent polypeptide-associated complex alpha subunit 2	cytoplasm	Cellular component	-
NCOA2	10499	nuclear receptor coactivator 2	chromatin organization	Biological process	-
TOPORS	10210	topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase	DNA binding	Molecular function	11278651
EIF2AK2	5610	eukaryotic translation initiation factor 2-alpha kinase 2	membrane	Cellular component	19946888
MKNK2	2872	MAP kinase interacting serine/threonine kinase 2	ATP binding	Molecular function	11463832
SGK3	23678	serum/glucocorticoid regulated kinase family, member 3	regulation of cell migration	Biological process	20919962
PAXIP1	22976	PAX interacting (with transcription-activation domain) protein 1	nuclear matrix	Cellular component	-
P2RX2	22953	purinergic receptor P2X, ligand gated ion channel, 2	sensory perception of taste	Biological process	-
T	6862	T, brachyury homolog (mouse)	nuclear chromatin	Cellular component	21632880
RAD51C	5889	RAD51 paralog C	perinuclear region of cytoplasm	Cellular component	16215984
RPS3A	6189	ribosomal protein S3A	gene expression	Biological process	-
PGLS	25796	6-phosphogluconolactonase	carbohydrate metabolic process	Biological process	-
AOC1	26	amine oxidase, copper containing 1	histamine oxidase activity	Molecular function	-
CHPF	79586	chondroitin polymerizing factor	metal ion binding	Molecular function	-
STAR	6770	steroidogenic acute regulatory protein	cellular response to cAMP	Biological process	-
SCARF1	8578	scavenger receptor class F, member 1	receptor-mediated endocytosis	Biological process	9395444
NMNAT3	349565	nicotinamide nucleotide adenylyltransferase 3	mitochondrion	Cellular component	16118205
CSF3R	1441	colony stimulating factor 3 receptor (granulocyte)	signal transduction	Biological process	1371413
CDH6	1004	cadherin 6, type 2, K-cadherin (fetal kidney)	calcium ion binding	Molecular function	-
PAN3	255967	PAN3 poly(A) specific ribonuclease subunit	gene expression	Biological process	-
ATP2B3	492	ATPase, Ca++ transporting, plasma membrane 3	metal ion binding	Molecular function	-
PLA2G10	8399	phospholipase A2, group X	phosphatidylcholine acyl-chain remodeling	Biological process	-
CLIP2	7461	CAP-GLY domain containing linker protein 2	microtubule plus-end binding	Molecular function	-
EXOSC10	5394	exosome component 10	exoribonuclease activity	Molecular function	17174896
BHMG1	388553	basic helix-loop-helix and HMG box domain containing 1	protein dimerization activity	Molecular function	-
CREB1	1385	cAMP responsive element binding protein 1	axon guidance	Biological process	-
ASAH2	56624	N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2	integral component of membrane	Cellular component	-
TYRP1	7306	tyrosinase-related protein 1	melanocyte differentiation	Biological process	-
SETMAR	6419	SET domain and mariner transposase fusion gene	structure-specific DNA binding	Molecular function	21491884
RECK	8434	reversion-inducing-cysteine-rich protein with kazal motifs	membrane	Cellular component	9789069
ADRB1	153	adrenoceptor beta 1	positive regulation of cation channel activity	Biological process	-
MAFG	4097	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G	regulation of transcription, DNA-templated	Biological process	-
SYNE3	161176	spectrin repeat containing, nuclear envelope family member 3	protein binding	Molecular function	18396275
EXT1	2131	exostosin glycosyltransferase 1	heparan sulfate proteoglycan biosynthetic process	Biological process	-
MYL9	10398	myosin, light chain 9, regulatory	Z disc	Cellular component	-
HOXC8	3224	homeobox C8	transcription, DNA-templated	Biological process	-
NSF	4905	N-ethylmaleimide-sensitive factor	protein kinase binding	Molecular function	-
IMPA2	3613	inositol(myo)-1(or 4)-monophosphatase 2	metal ion binding	Molecular function	-
DNAJB9	4189	DnaJ (Hsp40) homolog, subfamily B, member 9	ER-associated ubiquitin-dependent protein catabolic process	Biological process	18400946
USP12	219333	ubiquitin specific peptidase 12	cysteine-type endopeptidase activity	Molecular function	19075014
FLII	2314	flightless I homolog (Drosophila)	protein binding	Molecular function	10366446
ANXA5	308	annexin A5	signal transduction	Biological process	16130169
MAEL	84944	maelstrom spermatogenic transposon silencer	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
NPBWR2	2832	neuropeptides B/W receptor 2	plasma membrane	Cellular component	-
NUBP1	4682	nucleotide binding protein 1	nucleotide binding	Molecular function	7926816
ZNF558	148156	zinc finger protein 558	transcription, DNA-templated	Biological process	-
CACNA2D2	9254	calcium channel, voltage-dependent, alpha 2/delta subunit 2	small molecule metabolic process	Biological process	-
FGFR4	2264	fibroblast growth factor receptor 4	peptidyl-tyrosine phosphorylation	Biological process	18480409
TBX2	6909	T-box 2	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	11111039
AIMP1	9255	aminoacyl tRNA synthetase complex-interacting multifunctional protein 1	protein binding	Molecular function	11741979
SUMO1	7341	small ubiquitin-like modifier 1	cellular protein metabolic process	Biological process	-
GLRA3	8001	glycine receptor, alpha 3	extracellular-glycine-gated chloride channel activity	Molecular function	-
FAP	2191	fibroblast activation protein, alpha	metalloendopeptidase activity	Molecular function	9065413
BCL2	596	B-cell CLL/lymphoma 2	channel inhibitor activity	Molecular function	9219694
FERMT2	10979	fermitin family member 2	nucleus	Cellular component	22699938
TLDC1	57707	TBC/LysM-associated domain containing 1	protein binding	Molecular function	16189514
DYNLL1	8655	dynein, light chain, LC8-type 1	transcription, DNA-templated	Biological process	-
USP17L11	100287178	ubiquitin specific peptidase 17-like family member 11	regulation of proteasomal protein catabolic process	Biological process	-
DCLK1	9201	doublecortin-like kinase 1	receptor signaling protein activity	Molecular function	10036192
GLTSCR2	29997	glioma tumor suppressor candidate region gene 2	intracellular membrane-bounded organelle	Cellular component	-
HPSE	10855	heparanase	beta-glucuronidase activity	Molecular function	10395325
BAK1	578	BCL2-antagonist/killer 1	aging	Biological process	-
DNHD1	144132	dynein heavy chain domain 1	microtubule motor activity	Molecular function	-
IFNW1	3467	interferon, omega 1	positive regulation of peptidyl-serine phosphorylation of STAT protein	Biological process	-
EDEM2	55741	ER degradation enhancer, mannosidase alpha-like 2	endoplasmic reticulum membrane	Cellular component	-
HPGDS	27306	hematopoietic prostaglandin D synthase	signal transduction	Biological process	9353279
SETD8	387893	SET domain containing (lysine methyltransferase) 8	nucleus	Cellular component	-
CFLAR	8837	CASP8 and FADD-like apoptosis regulator	necroptotic process	Biological process	-
CLCN3	1182	chloride channel, voltage-sensitive 3	voltage-gated chloride channel activity	Molecular function	-
CALM1	801	calmodulin 1 (phosphorylase kinase, delta)	Fc-epsilon receptor signaling pathway	Biological process	-
CHMP1A	5119	charged multivesicular body protein 1A	zinc ion binding	Molecular function	8863740
RPGRIP1L	23322	RPGRIP1-like	determination of left/right symmetry	Biological process	-
PNPT1	87178	polyribonucleotide nucleotidyltransferase 1	mitochondrial intermembrane space	Cellular component	16966381
HIST1H4E	8367	histone cluster 1, H4e	nucleosome	Cellular component	3035717
ADAP1	11033	ArfGAP with dual PH domains 1	inositol 1,3,4,5 tetrakisphosphate binding	Molecular function	12018390
FGD4	121512	FYVE, RhoGEF and PH domain containing 4	small GTPase binding	Molecular function	-
CASC3	22794	cancer susceptibility candidate 3	ribonucleoprotein complex	Cellular component	-
WNT7A	7476	wingless-type MMTV integration site family, member 7A	positive regulation of canonical Wnt signaling pathway	Biological process	-
VPS45	11311	vacuolar protein sorting 45 homolog (S. cerevisiae)	integral component of membrane	Cellular component	-
NCF4	4689	neutrophil cytosolic factor 4, 40kDa	protein binding	Molecular function	11483497
CORO1A	11151	coronin, actin binding protein, 1A	negative regulation of vesicle fusion	Biological process	-
SORL1	6653	sortilin-related receptor, L(DLR class) A repeats containing	nuclear envelope lumen	Cellular component	17855360
SLC50A1	55974	solute carrier family 50 (sugar efflux transporter), member 1	carbohydrate transport	Biological process	-
CD4	920	CD4 molecule	transmembrane signaling receptor activity	Molecular function	10358157
SLC32A1	140679	solute carrier family 32 (GABA vesicular transporter), member 1	inhibitory synapse	Cellular component	-
ZNF846	162993	zinc finger protein 846	DNA binding	Molecular function	-
GOSR2	9570	golgi SNAP receptor complex member 2	SNAP receptor activity	Molecular function	-
JPH2	57158	junctophilin 2	calcium ion transmembrane transport	Biological process	-
SFRP1	6422	secreted frizzled-related protein 1	negative regulation of transcription, DNA-templated	Biological process	16532032
MSRA	4482	methionine sulfoxide reductase A	cytoplasm	Cellular component	-
RGS1	5996	regulator of G-protein signaling 1	GTPase activator activity	Molecular function	10747990
CERS2	29956	ceramide synthase 2	membrane	Cellular component	19946888
DSE	29940	dermatan sulfate epimerase	glycosaminoglycan metabolic process	Biological process	-
SEH1L	81929	SEH1-like (S. cerevisiae)	viral life cycle	Biological process	-
RBFA	79863	ribosome binding factor A (putative)	cellular_component	Cellular component	-
ATE1	11101	arginyltransferase 1	protein arginylation	Biological process	9858543
HOXA11	3207	homeobox A11	nucleus	Cellular component	-
EZR	7430	ezrin	actin cytoskeleton	Cellular component	10793131
MSX1	4487	msh homeobox 1	in utero embryonic development	Biological process	-
PARVA	55742	parvin, alpha	protein binding	Molecular function	12432066
PEX13	5194	peroxisomal biogenesis factor 13	locomotory behavior	Biological process	-
CIB1	10519	calcium and integrin binding 1 (calmyrin)	positive regulation of cell proliferation	Biological process	-
SLC9A7	84679	solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7	sodium ion transmembrane transport	Biological process	-
WWTR1	25937	WW domain containing transcription regulator 1	regulation of SMAD protein import into nucleus	Biological process	18568018
GOLT1B	51026	golgi transport 1B	signal transduction	Biological process	12761501
MMP13	4322	matrix metallopeptidase 13	growth plate cartilage development	Biological process	-
SFRP1	6422	secreted frizzled-related protein 1	positive regulation of canonical Wnt signaling pathway	Biological process	18941195
AMER3	205147	APC membrane recruitment protein 3	protein binding	Molecular function	24251807
NKX3-2	579	NK3 homeobox 2	spleen development	Biological process	-
DCDC2	51473	doublecortin domain containing 2	regulation of Wnt signaling pathway	Biological process	25557784
DEFB103B	55894	defensin, beta 103B	innate immune response	Biological process	-
GRIN2B	2904	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	neuron projection	Cellular component	-
HELB	92797	helicase (DNA) B	ATP binding	Molecular function	-
DUOX2	50506	dual oxidase 2	cuticle development	Biological process	-
GPANK1	7918	G patch domain and ankyrin repeats 1	protein binding	Molecular function	25416956
RNF130	55819	ring finger protein 130	nucleoplasm	Cellular component	-
TAF1	6872	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa	TBP-class protein binding	Molecular function	9660973
MET	4233	MET proto-oncogene, receptor tyrosine kinase	hepatocyte growth factor receptor signaling pathway	Biological process	-
NABP1	64859	nucleic acid binding protein 1	RNA binding	Molecular function	-
CASP8AP2	9994	caspase 8 associated protein 2	apoptotic signaling pathway	Biological process	10235259
SMAD6	4091	SMAD family member 6	protein binding	Molecular function	11483516
ACTR3	10096	ARP3 actin-related protein 3 homolog (yeast)	lamellipodium	Cellular component	-
C9orf78	51759	chromosome 9 open reading frame 78	cytoplasm	Cellular component	-
PRKCD	5580	protein kinase C, delta	negative regulation of platelet aggregation	Biological process	-
TSPO	706	translocator protein (18kDa)	contact inhibition	Biological process	-
PRKCZ	5590	protein kinase C, zeta	negative regulation of protein complex assembly	Biological process	15069075
FGF2	2247	fibroblast growth factor 2 (basic)	positive regulation of endothelial cell chemotaxis to fibroblast growth factor	Biological process	16756958
P2RY1	5028	purinergic receptor P2Y, G-protein coupled, 1	response to mechanical stimulus	Biological process	-
MSX1	4487	msh homeobox 1	embryonic forelimb morphogenesis	Biological process	-
CDC42	998	cell division cycle 42	neuron projection	Cellular component	21048939
KLKB1	3818	kallikrein B, plasma (Fletcher factor) 1	proteolysis	Biological process	1993180
TRIM11	81559	tripartite motif containing 11	negative regulation of neurogenesis	Biological process	-
WIBG	84305	within bgcn homolog (Drosophila)	positive regulation of translation	Biological process	18026120
FAT3	120114	FAT atypical cadherin 3	calcium ion binding	Molecular function	-
FLOT1	10211	flotillin 1	cellular response to exogenous dsRNA	Biological process	25204797
ZXDC	79364	ZXD family zinc finger C	nucleic acid binding	Molecular function	-
SOX4	6659	SRY (sex determining region Y)-box 4	RNA polymerase II transcription coactivator activity	Molecular function	-
EXOSC2	23404	exosome component 2	nuclear polyadenylation-dependent rRNA catabolic process	Biological process	-
PTHLH	5744	parathyroid hormone-like hormone	lung alveolus development	Biological process	-
OPRD1	4985	opioid receptor, delta 1	vesicle	Cellular component	-
RNF138	51444	ring finger protein 138, E3 ubiquitin protein ligase	protein ubiquitination	Biological process	-
CD8B	926	CD8b molecule	coreceptor activity	Molecular function	11131152
GMFG	9535	glia maturation factor, gamma	intracellular	Cellular component	-
TAS2R4	50832	taste receptor, type 2, member 4	signal transduction	Biological process	10761934
CLCF1	23529	cardiotrophin-like cytokine factor 1	positive regulation of cell proliferation	Biological process	10966616
DLG1	1739	discs, large homolog 1 (Drosophila)	reproductive structure development	Biological process	-
TMED10	10972	transmembrane emp24-like trafficking protein 10 (yeast)	melanosome	Cellular component	-
KIF23	9493	kinesin family member 23	mitotic spindle	Cellular component	16236794
NFKBIB	4793	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	cellular response to lipopolysaccharide	Biological process	-
RREB1	6239	ras responsive element binding protein 1	metal ion binding	Molecular function	-
AQP2	359	aquaporin 2 (collecting duct)	response to salt stress	Biological process	-
GNAS	2778	GNAS complex locus	transmembrane transport	Biological process	-
CYP2F1	1572	cytochrome P450, family 2, subfamily F, polypeptide 1	intracellular membrane-bounded organelle	Cellular component	10383923
HSPA5	3309	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	extracellular exosome	Cellular component	19056867
BAX	581	BCL2-associated X protein	lipid binding	Molecular function	14522999
TP53TG5	27296	TP53 target 5	molecular_function	Molecular function	-
PRPF8	10594	pre-mRNA processing factor 8	mRNA splicing, via spliceosome	Biological process	-
SLC17A3	10786	solute carrier family 17 (organic anion transporter), member 3	cytoplasm	Cellular component	20810651
ARRB1	408	arrestin, beta 1	angiotensin receptor binding	Molecular function	15611106
ALKBH3	221120	alkB, alkylation repair homolog 3 (E. coli)	cytosine C-5 DNA demethylase activity	Molecular function	-
GJA1	2697	gap junction protein, alpha 1, 43kDa	atrial ventricular junction remodeling	Biological process	-
FGF1	2246	fibroblast growth factor 1 (acidic)	organ induction	Biological process	-
TNFRSF21	27242	tumor necrosis factor receptor superfamily, member 21	oligodendrocyte apoptotic process	Biological process	-
DBNDD2	55861	dysbindin (dystrobrevin binding protein 1) domain containing 2	protein binding	Molecular function	16618118
CCM2	83605	cerebral cavernous malformation 2	vasculogenesis	Biological process	14740320
HINT1	3094	histidine triad nucleotide binding protein 1	cytoskeleton	Cellular component	8812426
CLDN5	7122	claudin 5	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules	Biological process	-
MEIS2	4212	Meis homeobox 2	transcription cofactor activity	Molecular function	-
TKTL2	84076	transketolase-like 2	transketolase activity	Molecular function	-
CDKN1A	1026	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	response to arsenic-containing substance	Biological process	-
FCRL6	343413	Fc receptor-like 6	integral component of membrane	Cellular component	-
GNG3	2785	guanine nucleotide binding protein (G protein), gamma 3	energy reserve metabolic process	Biological process	-
COX6C	1345	cytochrome c oxidase subunit VIc	generation of precursor metabolites and energy	Biological process	2849755
CCR1	1230	chemokine (C-C motif) receptor 1	metabolic process	Biological process	10734056
ATF7IP2	80063	activating transcription factor 7 interacting protein 2	regulation of transcription, DNA-templated	Biological process	-
WDPCP	51057	WD repeat containing planar cell polarity effector	axoneme	Cellular component	-
CNGA1	1259	cyclic nucleotide gated channel alpha 1	voltage-gated potassium channel activity	Molecular function	-
PAOX	196743	polyamine oxidase (exo-N4-amino)	N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity	Molecular function	-
CD80	941	CD80 molecule	intracellular signal transduction	Biological process	9915850
XPNPEP1	7511	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble	metalloaminopeptidase activity	Molecular function	18515364
PSME3	10197	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)	positive regulation of endopeptidase activity	Biological process	18309296
CRP	1401	C-reactive protein, pentraxin-related	protein homodimerization activity	Molecular function	-
HS3ST3B1	9953	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1	[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity	Molecular function	-
NACC2	138151	NACC family member 2, BEN and BTB (POZ) domain containing	posttranscriptional regulation of gene expression	Biological process	22926524
PIKFYVE	200576	phosphoinositide kinase, FYVE finger containing	protein localization to nucleus	Biological process	17909029
CEBPE	1053	CCAAT/enhancer binding protein (C/EBP), epsilon	defense response	Biological process	8661101
ATAD1	84896	ATPase family, AAA domain containing 1	peroxisomal membrane	Cellular component	21525035
ALDH1A2	8854	aldehyde dehydrogenase 1 family, member A2	negative regulation of cell proliferation	Biological process	16166285
UGT1A9	54600	UDP glucuronosyltransferase 1 family, polypeptide A9	negative regulation of fatty acid metabolic process	Biological process	20610558
KIF18B	146909	kinesin family member 18B	cytoplasm	Cellular component	-
ACD	65057	adrenocortical dysplasia homolog (mouse)	telomere maintenance	Biological process	-
CD9	928	CD9 molecule	single fertilization	Biological process	-
BCAP31	10134	B-cell receptor-associated protein 31	clathrin-coated vesicle	Cellular component	-
NCKAP1	10787	NCK-associated protein 1	viral process	Biological process	-
APOBEC3H	164668	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H	cytoplasmic mRNA processing body	Cellular component	22915799
TBC1D24	57465	TBC1 domain family, member 24	regulation of cilium assembly	Biological process	17646400
TIMM21	29090	translocase of inner mitochondrial membrane 21 homolog (yeast)	mitochondrial respiratory chain complex I assembly	Biological process	23260140
NAA35	60560	N(alpha)-acetyltransferase 35, NatC auxiliary subunit	polysome	Cellular component	19398576
AXIN2	8313	axin 2	GTPase activator activity	Molecular function	-
UBA52	7311	ubiquitin A-52 residue ribosomal protein fusion product 1	cytosolic large ribosomal subunit	Cellular component	12962325
HDAC4	9759	histone deacetylase 4	zinc ion binding	Molecular function	18614528
GEMIN2	8487	gem (nuclear organelle) associated protein 2	cytosol	Cellular component	-
HSD17B7	51478	hydroxysteroid (17-beta) dehydrogenase 7	estrogen biosynthetic process	Biological process	-
SLC6A1	6529	solute carrier family 6 (neurotransmitter transporter), member 1	response to estradiol	Biological process	-
CDC42SE1	56882	CDC42 small effector 1	structural molecule activity	Molecular function	-
FGA	2243	fibrinogen alpha chain	fibrinogen complex	Cellular component	8910396
AQP2	359	aquaporin 2 (collecting duct)	female pregnancy	Biological process	-
PARP1	142	poly (ADP-ribose) polymerase 1	transcription from RNA polymerase II promoter	Biological process	10944198
BCL10	8915	B-cell CLL/lymphoma 10	cytoplasmic microtubule	Cellular component	23264731
SLC34A1	6569	solute carrier family 34 (type II sodium/phosphate cotransporter), member 1	kidney development	Biological process	-
BZW2	28969	basic leucine zipper and W2 domains 2	cell differentiation	Biological process	-
ANP32B	10541	acidic (leucine-rich) nuclear phosphoprotein 32 family, member B	nucleosome assembly	Biological process	20538007
RPS3A	6189	ribosomal protein S3A	cytosol	Cellular component	-
IL18	3606	interleukin 18	negative regulation of myoblast differentiation	Biological process	-
POLR2G	5436	polymerase (RNA) II (DNA directed) polypeptide G	somatic stem cell maintenance	Biological process	-
APOA2	336	apolipoprotein A-II	high-density lipoprotein particle	Cellular component	17264082
AKT1	207	v-akt murine thymoma viral oncogene homolog 1	response to food	Biological process	-
TNS4	84951	tensin 4	cytoskeleton	Cellular component	-
RPL3	6122	ribosomal protein L3	poly(A) RNA binding	Molecular function	22658674
RYR2	6262	ryanodine receptor 2 (cardiac)	Z disc	Cellular component	-
CITED2	10370	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	adrenal cortex formation	Biological process	-
CAPN13	92291	calpain 13	cytoplasm	Cellular component	-
TRIM54	57159	tripartite motif containing 54	protein binding	Molecular function	25416956
CYCS	54205	cytochrome c, somatic	nucleus	Cellular component	-
SPATA4	132851	spermatogenesis associated 4	protein binding	Molecular function	25416956
GDE1	51573	glycerophosphodiester phosphodiesterase 1	integral component of membrane	Cellular component	10760272
PML	5371	promyelocytic leukemia	response to gamma radiation	Biological process	-
GJB3	2707	gap junction protein, beta 3, 31kDa	integral component of membrane	Cellular component	-
OSBPL7	114881	oxysterol binding protein-like 7	autophagosome	Cellular component	21669198
MED25	81857	mediator complex subunit 25	positive regulation of cell cycle arrest	Biological process	17641689
SMO	6608	smoothened, frizzled class receptor	dorsal/ventral neural tube patterning	Biological process	-
NENF	29937	neudesin neurotrophic factor	nucleoplasm	Cellular component	-
C6	729	complement component 6	complement activation	Biological process	2808363
MAGEA9	4108	melanoma antigen family A9	molecular_function	Molecular function	-
FOXF1	2294	forkhead box F1	pancreas development	Biological process	19500772
KIF5A	3798	kinesin family member 5A	perinuclear region of cytoplasm	Cellular component	-
KIF13B	23303	kinesin family member 13B	protein binding	Molecular function	10859302
RYR2	6262	ryanodine receptor 2 (cardiac)	response to muscle activity	Biological process	17875969
HELT	391723	helt bHLH transcription factor	transcription factor complex	Cellular component	-
PAX2	5076	paired box 2	protein kinase B signaling	Biological process	-
PUSL1	126789	pseudouridylate synthase-like 1	pseudouridine synthase activity	Molecular function	-
CTCFL	140690	CCCTC-binding factor (zinc finger protein)-like	transcription, DNA-templated	Biological process	-
GNG2	54331	guanine nucleotide binding protein (G protein), gamma 2	small molecule metabolic process	Biological process	-
PRF1	5551	perforin 1 (pore forming protein)	wide pore channel activity	Molecular function	20889983
GHRL	51738	ghrelin/obestatin prepropeptide	adult feeding behavior	Biological process	-
CDHR4	389118	cadherin-related family member 4	integral component of membrane	Cellular component	-
PCSK2	5126	proprotein convertase subtilisin/kexin type 2	serine-type endopeptidase activity	Molecular function	7626024
SPI1	6688	Spi-1 proto-oncogene	histone H3 acetylation	Biological process	20139074
PYCR2	29920	pyrroline-5-carboxylate reductase family, member 2	oxidation-reduction process	Biological process	-
KLF4	9314	Kruppel-like factor 4 (gut)	core promoter proximal region sequence-specific DNA binding	Molecular function	21539536
DHFR	1719	dihydrofolate reductase	response to methotrexate	Biological process	-
DICER1	23405	dicer 1, ribonuclease type III	production of siRNA involved in RNA interference	Biological process	15973356
APLP1	333	amyloid beta (A4) precursor-like protein 1	integral component of membrane	Cellular component	-
NDUFA13	51079	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13	reactive oxygen species metabolic process	Biological process	16826196
MRVI1	10335	murine retrovirus integration site 1 homolog	cGMP-mediated signaling	Biological process	-
VAMP7	6845	vesicle-associated membrane protein 7	membrane organization	Biological process	-
CXCR4	7852	chemokine (C-X-C motif) receptor 4	cytokine binding	Molecular function	-
ENOPH1	58478	enolase-phosphatase 1	cellular nitrogen compound metabolic process	Biological process	-
APOLD1	81575	apolipoprotein L domain containing 1	response to hypoxia	Biological process	-
MAP4K3	8491	mitogen-activated protein kinase kinase kinase kinase 3	response to tumor necrosis factor	Biological process	9275185
CACNA1I	8911	calcium channel, voltage-dependent, T type, alpha 1I subunit	membrane depolarization during action potential	Biological process	-
CACYBP	27101	calcyclin binding protein	cell body	Cellular component	-
P2RX7	5027	purinergic receptor P2X, ligand gated ion channel, 7	scaffold protein binding	Molecular function	-
SNX4	8723	sorting nexin 4	endocytic recycling	Biological process	17994011
GCH1	2643	GTP cyclohydrolase 1	negative regulation of blood pressure	Biological process	-
WAC	51322	WW domain containing adaptor with coiled-coil	chromatin binding	Molecular function	21329877
CLTA	1211	clathrin, light chain A	intracellular membrane-bounded organelle	Cellular component	-
PIGT	51604	phosphatidylinositol glycan anchor biosynthesis, class T	protein binding	Molecular function	11483512
QRICH1	54870	glutamine-rich 1	molecular_function	Molecular function	-
RPS7	6201	ribosomal protein S7	viral life cycle	Biological process	-
KCNQ3	3786	potassium channel, voltage gated KQT-like subfamily Q, member 3	axon guidance	Biological process	-
TRMT61A	115708	tRNA methyltransferase 61A	tRNA (m1A) methyltransferase complex	Cellular component	-
IL12RB2	3595	interleukin 12 receptor, beta 2	cytokine-mediated signaling pathway	Biological process	8943050
THBS1	7057	thrombospondin 1	cell cycle arrest	Biological process	17596205
PIP4K2B	8396	phosphatidylinositol-5-phosphate 4-kinase, type II, beta	phospholipid metabolic process	Biological process	-
ZFP37	7539	ZFP37 zinc finger protein	sequence-specific DNA binding transcription factor activity	Molecular function	9585434
ERCC6L2	375748	excision repair cross-complementation group 6-like 2	DNA repair	Biological process	-
HAP1	9001	huntingtin-associated protein 1	protein localization	Biological process	18922795
PEAR1	375033	platelet endothelial aggregation receptor 1	integral component of membrane	Cellular component	-
PON2	5445	paraoxonase 2	lysosome	Cellular component	-
BLK	640	BLK proto-oncogene, Src family tyrosine kinase	B cell receptor signaling pathway	Biological process	876631
CNTNAP2	26047	contactin associated protein-like 2	neuronal cell body	Cellular component	-
PTK2	5747	protein tyrosine kinase 2	programmed cell death	Biological process	-
BCL2L10	10017	BCL2-like 10 (apoptosis facilitator)	protein heterodimerization activity	Molecular function	-
SFN	2810	stratifin	phosphoprotein binding	Molecular function	-
LRRC25	126364	leucine rich repeat containing 25	integral component of membrane	Cellular component	-
SLC25A15	10166	solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15	urea cycle	Biological process	-
GFRAL	389400	GDNF family receptor alpha like	plasma membrane	Cellular component	-
PAXIP1	22976	PAX interacting (with transcription-activation domain) protein 1	protein binding	Molecular function	15456759
HSPD1	3329	heat shock 60kDa protein 1 (chaperonin)	p53 binding	Molecular function	18086682
ATF4	468	activating transcription factor 4	dendrite membrane	Cellular component	-
CAPN3	825	calpain 3, (p94)	calcium ion binding	Molecular function	-
OXTR	5021	oxytocin receptor	response to drug	Biological process	-
CHEK1	1111	checkpoint kinase 1	G2/M transition of mitotic cell cycle	Biological process	-
UBOX5	22888	U-box domain containing 5	nuclear body	Cellular component	11274149
NPY2R	4887	neuropeptide Y receptor Y2	calcium channel regulator activity	Molecular function	8132547
KCTD8	386617	potassium channel tetramerization domain containing 8	receptor complex	Cellular component	-
CCRN4L	25819	CCR4 carbon catabolite repression 4-like (S. cerevisiae)	cytoplasmic mRNA processing body	Cellular component	-
LRP12	29967	low density lipoprotein receptor-related protein 12	low-density lipoprotein receptor activity	Molecular function	12809483
WNT5B	81029	wingless-type MMTV integration site family, member 5B	extracellular exosome	Cellular component	19056867
SCAND1	51282	SCAN domain containing 1	identical protein binding	Molecular function	-
DCXR	51181	dicarbonyl/L-xylulose reductase	cytoplasmic microtubule	Cellular component	23264731
CHRD	8646	chordin	osteoblast differentiation	Biological process	-
EGFR	1956	epidermal growth factor receptor	positive regulation of protein phosphorylation	Biological process	20551055
OGT	8473	O-linked N-acetylglucosamine (GlcNAc) transferase	positive regulation of histone H3-K4 methylation	Biological process	-
ZNF622	90441	zinc finger protein 622	positive regulation of MAPK cascade	Biological process	21771788
PSMC2	5701	proteasome (prosome, macropain) 26S subunit, ATPase, 2	viral process	Biological process	-
PUS7L	83448	pseudouridylate synthase 7 homolog (S. cerevisiae)-like	tRNA processing	Biological process	-
MYH10	4628	myosin, heavy chain 10, non-muscle	actin filament-based movement	Biological process	15845534
ANXA3	306	annexin A3	calcium-dependent protein binding	Molecular function	15226301
SHPRH	257218	SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase	protein binding	Molecular function	25416956
ARHGAP17	55114	Rho GTPase activating protein 17	bicellular tight junction	Cellular component	-
DNAJC13	23317	DnaJ (Hsp40) homolog, subfamily C, member 13	osteoblast differentiation	Biological process	16210410
SPTAN1	6709	spectrin, alpha, non-erythrocytic 1	calmodulin binding	Molecular function	-
PARK2	5071	parkin RBR E3 ubiquitin protein ligase	negative regulation of cell death	Biological process	12150907
RAB30	27314	RAB30, member RAS oncogene family	cis-Golgi network	Cellular component	22188167
ABLIM1	3983	actin binding LIM protein 1	lamellipodium assembly	Biological process	22684256
C1QTNF3	114899	C1q and tumor necrosis factor related protein 3	collagen trimer	Cellular component	-
NPY5R	4889	neuropeptide Y receptor Y5	synaptic transmission	Biological process	-
PAK1	5058	p21 protein (Cdc42/Rac)-activated kinase 1	Fc-epsilon receptor signaling pathway	Biological process	-
ESRP2	80004	epithelial splicing regulatory protein 2	nucleotide binding	Molecular function	-
CENPF	1063	centromere protein F, 350/400kDa	pronucleus	Cellular component	-
GAL	51083	galanin/GMAP prepropeptide	response to drug	Biological process	-
MUSK	4593	muscle, skeletal, receptor tyrosine kinase	positive regulation of neuron apoptotic process	Biological process	-
GLP1R	2740	glucagon-like peptide 1 receptor	plasma membrane	Cellular component	-
SNX17	9784	sorting nexin 17	cytoplasm	Cellular component	-
VEGFB	7423	vascular endothelial growth factor B	chemoattractant activity	Molecular function	19275959
PPIB	5479	peptidylprolyl isomerase B (cyclophilin B)	chaperone-mediated protein folding	Biological process	20089953
CRYGD	1421	crystallin, gamma D	lens development in camera-type eye	Biological process	-
FOSB	2354	FBJ murine osteosarcoma viral oncogene homolog B	cellular response to hormone stimulus	Biological process	-
REST	5978	RE1-silencing transcription factor	transcription from RNA polymerase II promoter	Biological process	-
RBM8A	9939	RNA binding motif protein 8A	RNA splicing	Biological process	-
NARF	26502	nuclear prelamin A recognition factor	NADH dehydrogenase activity	Molecular function	-
CNTN4	152330	contactin 4	neuron cell-cell adhesion	Biological process	14571131
GPSM3	63940	G-protein signaling modulator 3	cellular_component	Cellular component	-
MAGI2	9863	membrane associated guanylate kinase, WW and PDZ domain containing 2	mitotic cell cycle arrest	Biological process	-
MSX2	4488	msh homeobox 2	embryonic forelimb morphogenesis	Biological process	-
NPR2	4882	natriuretic peptide receptor 2	protein kinase activity	Molecular function	-
CLPP	8192	caseinolytic mitochondrial matrix peptidase proteolytic subunit	endopeptidase Clp complex	Cellular component	11923310
ITGA2	3673	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	mammary gland development	Biological process	-
ABHD1	84696	abhydrolase domain containing 1	metabolic process	Biological process	-
UNC93B1	81622	unc-93 homolog B1 (C. elegans)	defense response to virus	Biological process	-
PIK3R4	30849	phosphoinositide-3-kinase, regulatory subunit 4	phosphatidylinositol biosynthetic process	Biological process	-
JMJD6	23210	jumonji domain containing 6	receptor activity	Molecular function	-
COL5A2	1290	collagen, type V, alpha 2	negative regulation of endodermal cell differentiation	Biological process	23154389
TTN	7273	titin	platelet degranulation	Biological process	-
FAM13C	220965	family with sequence similarity 13, member C	protein binding	Molecular function	25416956
POLR1D	51082	polymerase (RNA) I polypeptide D, 16kDa	transcription from RNA polymerase III promoter	Biological process	-
TUB	7275	tubby bipartite transcription factor	extracellular region	Cellular component	-
CAMK2B	816	calcium/calmodulin-dependent protein kinase II beta	regulation of synaptic transmission, cholinergic	Biological process	-
TOPORS	10210	topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase	positive regulation of ubiquitin-protein transferase activity	Biological process	15247280
APOE	348	apolipoprotein E	lipoprotein catabolic process	Biological process	-
ZNF580	51157	zinc finger protein 580	sequence-specific DNA binding RNA polymerase II transcription factor activity	Molecular function	-
CBX4	8535	chromobox homolog 4	phosphoprotein binding	Molecular function	-
TGFB3	7043	transforming growth factor, beta 3	positive regulation of protein secretion	Biological process	18505915
RPTOR	57521	regulatory associated protein of MTOR, complex 1	lysosome	Cellular component	20381137
PSMD6	9861	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	cytosol	Cellular component	-
DBP	1628	D site of albumin promoter (albumin D-box) binding protein	liver development	Biological process	-
KCNA2	3737	potassium channel, voltage gated shaker related subfamily A, member 2	voltage-gated potassium channel complex	Cellular component	11086297
NUDT9	53343	nudix (nucleoside diphosphate linked moiety X)-type motif 9	intracellular	Cellular component	11385575
EHD4	30844	EH-domain containing 4	calcium ion binding	Molecular function	-
AKT1	207	v-akt murine thymoma viral oncogene homolog 1	epidermal growth factor receptor signaling pathway	Biological process	-
VEGFA	7422	vascular endothelial growth factor A	vascular endothelial growth factor receptor signaling pathway	Biological process	-
ATP5F1	515	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1	ATP synthesis coupled proton transport	Biological process	-
CXCL8	3576	chemokine (C-X-C motif) ligand 8	inflammatory response	Biological process	11483765
ABCD4	5826	ATP-binding cassette, sub-family D (ALD), member 4	lysosomal membrane	Cellular component	-
ZBED1	9189	zinc finger, BED-type containing 1	transposase activity	Molecular function	9887332
PPM1G	5496	protein phosphatase, Mg2+/Mn2+ dependent, 1G	cell cycle arrest	Biological process	-
APOE	348	apolipoprotein E	high-density lipoprotein particle	Cellular component	210174
GPCPD1	56261	glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)	glycerophosphocholine phosphodiesterase activity	Molecular function	-
DEDD2	162989	death effector domain containing 2	apoptotic nuclear changes	Biological process	11741985
SOX9	6662	SRY (sex determining region Y)-box 9	branching involved in ureteric bud morphogenesis	Biological process	-
LPAR1	1902	lysophosphatidic acid receptor 1	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway	Biological process	-
GALK1	2584	galactokinase 1	galactose catabolic process	Biological process	-
UPB1	51733	ureidopropionase, beta	metal ion binding	Molecular function	-
NAA10	8260	N(alpha)-acetyltransferase 10, NatA catalytic subunit	acetyltransferase activity	Molecular function	15496142
TBCE	6905	tubulin folding cofactor E	microtubule	Cellular component	8706133
MEF2A	4205	myocyte enhancer factor 2A	nucleoplasm	Cellular component	-
FCER1G	2207	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	integrin-mediated signaling pathway	Biological process	-
KPNA3	3839	karyopherin alpha 3 (importin alpha 4)	protein transporter activity	Molecular function	-
MTRNR2L1	100462977	MT-RNR2-like 1	extracellular region	Cellular component	-
SHC1	6464	SHC (Src homology 2 domain containing) transforming protein 1	regulation of growth	Biological process	-
OR10J6P	401973	olfactory receptor, family 10, subfamily J, member 6 pseudogene	integral component of membrane	Cellular component	-
INSM2	84684	insulinoma-associated 2	metal ion binding	Molecular function	-
ACSL6	23305	acyl-CoA synthetase long-chain family member 6	enzyme binding	Molecular function	20429931
PARK2	5071	parkin RBR E3 ubiquitin protein ligase	ubiquitin protein ligase binding	Molecular function	12150907
AHR	196	aryl hydrocarbon receptor	E-box binding	Molecular function	-
DAZ1	1617	deleted in azoospermia 1	positive regulation of translational initiation	Biological process	16001084
SSU72	29101	SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae)	cytoplasm	Cellular component	-
KLRF1	51348	killer cell lectin-like receptor subfamily F, member 1	membrane	Cellular component	10671213
DAND5	199699	DAN domain family member 5, BMP antagonist	negative regulation of BMP signaling pathway	Biological process	-
RNF5	6048	ring finger protein 5, E3 ubiquitin protein ligase	ligase activity	Molecular function	-
BAMBI	25805	BMP and activin membrane-bound inhibitor	frizzled binding	Molecular function	18838381
AIF1	199	allograft inflammatory factor 1	positive regulation of smooth muscle cell proliferation	Biological process	15117732
OLFML3	56944	olfactomedin-like 3	extracellular vesicle	Cellular component	24769233
RGPD6	729540	RANBP2-like and GRIP domain containing 6	cytoplasm	Cellular component	-
GPR143	4935	G protein-coupled receptor 143	lysosomal membrane	Cellular component	16621890
TAS2R10	50839	taste receptor, type 2, member 10	detection of chemical stimulus involved in sensory perception of bitter taste	Biological process	20022913
GABRG2	2566	gamma-aminobutyric acid (GABA) A receptor, gamma 2	dendrite membrane	Cellular component	-
ZNF501	115560	zinc finger protein 501	sequence-specific DNA binding transcription factor activity	Molecular function	-
E2F7	144455	E2F transcription factor 7	chorionic trophoblast cell differentiation	Biological process	-
IL6	3569	interleukin 6	response to drug	Biological process	-
CHRM1	1128	cholinergic receptor, muscarinic 1	cell proliferation	Biological process	1905013
MACC1	346389	metastasis associated in colon cancer 1	transcription, DNA-templated	Biological process	-
MYO1C	4641	myosin IC	calmodulin binding	Molecular function	-
NMRK2	27231	nicotinamide riboside kinase 2	intracellular	Cellular component	-
SLC9A6	10479	solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6	axon extension	Biological process	24035762
RHCG	51458	Rh family, C glycoprotein	basolateral plasma membrane	Cellular component	16928804
CER1	9350	cerberus 1, DAN family BMP antagonist	BMP binding	Molecular function	9660951
SLC6A11	6538	solute carrier family 6 (neurotransmitter transporter), member 11	brain development	Biological process	-
NACC1	112939	nucleus accumbens associated 1, BEN and BTB (POZ) domain containing	RNA polymerase II regulatory region sequence-specific DNA binding	Molecular function	-
IRAK4	51135	interleukin-1 receptor-associated kinase 4	endosome membrane	Cellular component	-
NCKAP1	10787	NCK-associated protein 1	regulation of protein localization	Biological process	-
AASDHPPT	60496	aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase	magnesium ion binding	Molecular function	18022563
GSDMD	79792	gasdermin D	protein binding	Molecular function	25416956
MICALL1	85377	MICAL-like 1	slow endocytic recycling	Biological process	19864458
KLHL41	10324	kelch-like family member 41	protein binding	Molecular function	23414517
CCL2	6347	chemokine (C-C motif) ligand 2	negative regulation of neuron apoptotic process	Biological process	12753088
GTF2H3	2967	general transcription factor IIH, polypeptide 3, 34kDa	transcription initiation from RNA polymerase II promoter	Biological process	-
SRC	6714	SRC proto-oncogene, non-receptor tyrosine kinase	regulation of protein binding	Biological process	-
PTGES	9536	prostaglandin E synthase	glutathione binding	Molecular function	18682561
GRIN3A	116443	glutamate receptor, ionotropic, N-methyl-D-aspartate 3A	neuronal cell body	Cellular component	17658481
Sep-03	55964	septin 3	GTP binding	Molecular function	-
NKX2-2	4821	NK2 homeobox 2	digestive tract development	Biological process	-
SFRP1	6422	secreted frizzled-related protein 1	hematopoietic stem cell differentiation	Biological process	19778523
TAF1	6872	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa	histone acetylation	Biological process	-
NR1H4	9971	nuclear receptor subfamily 1, group H, member 4	thyroid hormone receptor activity	Molecular function	-
SPATA31C2	645961	SPATA31 subfamily C, member 2	spermatogenesis	Biological process	-
MRPL37	51253	mitochondrial ribosomal protein L37	translation	Biological process	11543634
MAPK1	5594	mitogen-activated protein kinase 1	MyD88-dependent toll-like receptor signaling pathway	Biological process	-
SRGN	5552	serglycin	negative regulation of cytokine secretion	Biological process	-
AMPH	273	amphiphysin	synaptic vesicle	Cellular component	1628617
BOD1L2	284257	biorientation of chromosomes in cell division 1-like 2	microtubule organizing center	Cellular component	-
SOX9	6662	SRY (sex determining region Y)-box 9	negative regulation of photoreceptor cell differentiation	Biological process	-
MYLK3	91807	myosin light chain kinase 3	positive regulation of sarcomere organization	Biological process	-
HIF1A	3091	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	positive regulation of insulin secretion involved in cellular response to glucose stimulus	Biological process	-
PPARGC1A	10891	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	androgen receptor binding	Molecular function	15572661
TEX14	56155	testis expressed 14	attachment of spindle microtubules to kinetochore	Biological process	-
GPR1	2825	G protein-coupled receptor 1	neuropeptide binding	Molecular function	-
NCL	4691	nucleolin	protein binding	Molecular function	12427757
HLF	3131	hepatic leukemia factor	multicellular organismal development	Biological process	1386162
IGKV1-5	28299	immunoglobulin kappa variable 1-5	extracellular exosome	Cellular component	23376485
FZD5	7855	frizzled class receptor 5	integral component of membrane	Cellular component	-
GDF2	2658	growth differentiation factor 2	positive regulation of angiogenesis	Biological process	20406889
FBXL2	25827	F-box and leucine-rich repeat protein 2	protein monoubiquitination	Biological process	-
TRPV4	59341	transient receptor potential cation channel, subfamily V, member 4	cellular calcium ion homeostasis	Biological process	12724311
PGR	5241	progesterone receptor	steroid hormone receptor activity	Molecular function	-
TSSK2	23617	testis-specific serine kinase 2	multicellular organismal development	Biological process	-
UNC13A	23025	unc-13 homolog A (C. elegans)	regulation of synaptic transmission, glutamatergic	Biological process	15217342
MRPL47	57129	mitochondrial ribosomal protein L47	mitochondrial translational initiation	Biological process	-
RAB21	23011	RAB21, member RAS oncogene family	cleavage furrow	Cellular component	-
FAM129A	116496	family with sequence similarity 129, member A	positive regulation of translation	Biological process	-
GDPD1	284161	glycerophosphodiester phosphodiesterase domain containing 1	lipid metabolic process	Biological process	-
NOX5	79400	NADPH oxidase, EF-hand calcium binding domain 5	regulation of proton transport	Biological process	11483596
CRTAP	10491	cartilage associated protein	endoplasmic reticulum	Cellular component	19846465
TTN	7273	titin	skeletal muscle thin filament assembly	Biological process	9817758
CCDC53	51019	coiled-coil domain containing 53	biological_process	Biological process	-
DNASE1	1773	deoxyribonuclease I	deoxyribonuclease I activity	Molecular function	-
CREB1	1385	cAMP responsive element binding protein 1	fibroblast growth factor receptor signaling pathway	Biological process	-
BST1	683	bone marrow stromal cell antigen 1	phosphorus-oxygen lyase activity	Molecular function	-
GDPD4	220032	glycerophosphodiester phosphodiesterase domain containing 4	metal ion binding	Molecular function	-
MMP9	4318	matrix metallopeptidase 9	negative regulation of apoptotic process	Biological process	22984561
SON	6651	SON DNA binding protein	nuclear speck	Cellular component	21504830
LRIG1	26018	leucine-rich repeats and immunoglobulin-like domains 1	sensory perception of sound	Biological process	-
TET2	54790	tet methylcytosine dioxygenase 2	hematopoietic stem cell homeostasis	Biological process	-
BRD2	6046	bromodomain containing 2	chromatin binding	Molecular function	18406326
ANO7	50636	anoctamin 7	phospholipid scramblase activity	Molecular function	-
CYBA	1535	cytochrome b-245, alpha polypeptide	SH3 domain binding	Molecular function	7938008
HIST2H2AA4	723790	histone cluster 2, H2aa4	biological_process	Biological process	-
PLIN5	440503	perilipin 5	cytosol	Cellular component	-
SPRY3	10251	sprouty homolog 3 (Drosophila)	cytoplasm	Cellular component	-
HIST1H4I	8294	histone cluster 1, H4i	DNA replication-dependent nucleosome assembly	Biological process	14718166
ARG1	383	arginase 1	cellular response to hydrogen peroxide	Biological process	-
NTF3	4908	neurotrophin 3	negative regulation of neuron apoptotic process	Biological process	-
HEY2	23493	hes-related family bHLH transcription factor with YRPW motif 2	sequence-specific DNA binding transcription factor activity	Molecular function	15485867
BTN2A1	11120	butyrophilin, subfamily 2, member A1	integral component of plasma membrane	Cellular component	9382921
IKBKB	3551	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	protein binding	Molecular function	10521409
NFASC	23114	neurofascin	plasma membrane	Cellular component	-
PBK	55872	PDZ binding kinase	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
DNAJC11	55735	DnaJ (Hsp40) homolog, subfamily C, member 11	protein binding	Molecular function	17500595
LMX1B	4010	LIM homeobox transcription factor 1, beta	multicellular organismal development	Biological process	9590287
MAPK8	5599	mitogen-activated protein kinase 8	toll-like receptor 3 signaling pathway	Biological process	-
HRH1	3269	histamine receptor H1	G-protein coupled receptor signaling pathway	Biological process	-
MFAP1	4236	microfibrillar-associated protein 1	protein binding	Molecular function	22365833
SOX15	6665	SRY (sex determining region Y)-box 15	positive regulation of myoblast proliferation	Biological process	17363903
SLCO2A1	6578	solute carrier organic anion transporter family, member 2A1	prostaglandin transport	Biological process	-
PARK2	5071	parkin RBR E3 ubiquitin protein ligase	negative regulation of JNK cascade	Biological process	-
VAMP3	9341	vesicle-associated membrane protein 3	regulation of histamine secretion by mast cell	Biological process	18253931
MYCBP	26292	MYC binding protein	regulation of transcription, DNA-templated	Biological process	9797456
LOC400927-CSNK1E	102800317	LOC400927-CSNK1E readthrough	nucleus	Cellular component	-
EDN1	1906	endothelin 1	cellular response to glucocorticoid stimulus	Biological process	-
RGS10	6001	regulator of G-protein signaling 10	cytoplasm	Cellular component	-
NCOR1	9611	nuclear receptor corepressor 1	thalamus development	Biological process	-
TFRC	7037	transferrin receptor	regulation of cell growth	Biological process	7556058
Sep-07	989	septin 7	cilium morphogenesis	Biological process	-
SLC7A2	6542	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	nitric oxide biosynthetic process	Biological process	-
RAP1GAP2	23108	RAP1 GTPase activating protein 2	positive regulation of GTPase activity	Biological process	-
CKAP2L	150468	cytoskeleton associated protein 2-like	spindle pole	Cellular component	-
PSMD7	5713	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	innate immune response	Biological process	-
CHCHD2	51142	coiled-coil-helix-coiled-coil-helix domain containing 2	transcription factor binding	Molecular function	23303788
ARHGEF2	9181	Rho/Rac guanine nucleotide exchange factor (GEF) 2	Rho guanyl-nucleotide exchange factor activity	Molecular function	9857026
LRRC6	23639	leucine rich repeat containing 6	outer dynein arm assembly	Biological process	23122589
AIFM3	150209	apoptosis-inducing factor, mitochondrion-associated, 3	metal ion binding	Molecular function	-
LPCAT2	54947	lysophosphatidylcholine acyltransferase 2	glycerophospholipid biosynthetic process	Biological process	-
MDN1	23195	MDN1, midasin homolog (yeast)	ATPase activity	Molecular function	12102729
ARL1	400	ADP-ribosylation factor-like 1	retrograde transport, endosome to Golgi	Biological process	19224922
RSAD2	91543	radical S-adenosyl methionine domain containing 2	negative regulation of viral genome replication	Biological process	21957124
PROK2	60675	prokineticin 2	positive regulation of cytosolic calcium ion concentration	Biological process	12728244
HPS1	3257	Hermansky-Pudlak syndrome 1	blood coagulation	Biological process	-
ALOX12B	242	arachidonate 12-lipoxygenase, 12R type	hepoxilin biosynthetic process	Biological process	-
OIP5	11339	Opa interacting protein 5	chromocenter	Cellular component	-
RAE1	8480	ribonucleic acid export 1	mitotic cell cycle	Biological process	-
CTNS	1497	cystinosin, lysosomal cystine transporter	melanin biosynthetic process	Biological process	-
RNF144A	9781	ring finger protein 144A	zinc ion binding	Molecular function	-
SGPP1	81537	sphingosine-1-phosphate phosphatase 1	sphingolipid biosynthetic process	Biological process	-
POLR2D	5433	polymerase (RNA) II (DNA directed) polypeptide D	viral process	Biological process	-
PCDH12	51294	protocadherin 12	neuron recognition	Biological process	10380929
SLC22A6	9356	solute carrier family 22 (organic anion transporter), member 6	sodium-independent organic anion transmembrane transporter activity	Molecular function	-
CYP2A7	1549	cytochrome P450, family 2, subfamily A, polypeptide 7	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	Molecular function	-
MYH2	4620	myosin, heavy chain 2, skeletal muscle, adult	protein binding	Molecular function	17823310
RUVBL1	8607	RuvB-like AAA ATPase 1	Swr1 complex	Cellular component	24463511
CLIP1	6249	CAP-GLY domain containing linker protein 1	nucleic acid binding	Molecular function	-
CLIP1	6249	CAP-GLY domain containing linker protein 1	cytoplasm	Cellular component	-
NTRK1	4914	neurotrophic tyrosine kinase, receptor, type 1	neurotrophin binding	Molecular function	9290260
ZNHIT6	54680	zinc finger, HIT-type containing 6	enzyme binding	Molecular function	23382074
TP53	7157	tumor protein p53	Notch signaling pathway	Biological process	-
ITGB2	3689	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	innate immune response	Biological process	-
TP63	8626	tumor protein p63	cellular response to DNA damage stimulus	Biological process	19451233
ZNF683	257101	zinc finger protein 683	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
CYBA	1535	cytochrome b-245, alpha polypeptide	NADPH oxidase complex	Cellular component	1763037
LAMTOR1	55004	late endosomal/lysosomal adaptor, MAPK and MTOR activator 1	cellular response to amino acid stimulus	Biological process	20381137
CBL	867	Cbl proto-oncogene, E3 ubiquitin protein ligase	flotillin complex	Cellular component	-
FOXD4	2298	forkhead box D4	sequence-specific DNA binding RNA polymerase II transcription factor activity	Molecular function	-
VPS16	64601	vacuolar protein sorting 16 homolog (S. cerevisiae)	regulation of vacuole fusion, non-autophagic	Biological process	-
P2RY12	64805	purinergic receptor P2Y, G-protein coupled, 12	positive regulation of GTPase activity	Biological process	-
APITD1	378708	apoptosis-inducing, TAF9-like domain 1	small GTPase mediated signal transduction	Biological process	-
HSPG2	3339	heparan sulfate proteoglycan 2	chondrocyte differentiation	Biological process	-
JSRP1	126306	junctional sarcoplasmic reticulum protein 1	protein localization to membrane	Biological process	-
CPVL	54504	carboxypeptidase, vitellogenic-like	extracellular exosome	Cellular component	19056867
TRAPPC4	51399	trafficking protein particle complex 4	Rab guanyl-nucleotide exchange factor activity	Molecular function	-
NUB1	51667	negative regulator of ubiquitin-like proteins 1	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Biological process	16707496
TMX3	54495	thioredoxin-related transmembrane protein 3	integral component of membrane	Cellular component	-
DNAAF2	55172	dynein, axonemal, assembly factor 2	response to retinoic acid	Biological process	-
MRGPRF	116535	MAS-related GPR, member F	G-protein coupled receptor signaling pathway	Biological process	-
SALL4	57167	spalt-like transcription factor 4	nucleoplasm	Cellular component	-
HTR2A	3356	5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled	phospholipase C-activating serotonin receptor signaling pathway	Biological process	-
STX17	55014	syntaxin 17	ER to Golgi transport vesicle membrane	Cellular component	-
DLG2	1740	discs, large homolog 2 (Drosophila)	basolateral plasma membrane	Cellular component	-
BICD2	23299	bicaudal D homolog 2 (Drosophila)	plasma membrane	Cellular component	-
CHI3L2	1117	chitinase 3-like 2	carbohydrate binding	Molecular function	-
KIF1C	10749	kinesin family member 1C	microtubule binding	Molecular function	-
CSK	1445	c-src tyrosine kinase	regulation of Fc receptor mediated stimulatory signaling pathway	Biological process	-
VEGFA	7422	vascular endothelial growth factor A	tube formation	Biological process	19033661
POLR3G	10622	polymerase (RNA) III (DNA directed) polypeptide G (32kD)	innate immune response	Biological process	-
SART3	9733	squamous cell carcinoma antigen recognized by T cells 3	Cajal body	Cellular component	12578909
WAS	7454	Wiskott-Aldrich syndrome	negative regulation of cell motility	Biological process	22804504
NEK6	10783	NIMA-related kinase 6	chromosome segregation	Biological process	14563848
NAT14	57106	N-acetyltransferase 14 (GCN5-related, putative)	N-acetyltransferase activity	Molecular function	-
TGFB3	7043	transforming growth factor, beta 3	positive regulation of epithelial to mesenchymal transition	Biological process	-
SMAD5	4090	SMAD family member 5	intracellular	Cellular component	9759503
ATAD1	84896	ATPase family, AAA domain containing 1	cell junction	Cellular component	-
TBC1D15	64786	TBC1 domain family, member 15	regulation of GTPase activity	Biological process	-
GRHPR	9380	glyoxylate reductase/hydroxypyruvate reductase	NAD binding	Molecular function	10484776
ZNF492	57615	zinc finger protein 492	regulation of transcription, DNA-templated	Biological process	-
OPRD1	4985	opioid receptor, delta 1	cellular response to growth factor stimulus	Biological process	-
DARS2	55157	aspartyl-tRNA synthetase 2, mitochondrial	gene expression	Biological process	-
GPC1	2817	glypican 1	negative regulation of fibroblast growth factor receptor signaling pathway	Biological process	-
HSPA8	3312	heat shock 70kDa protein 8	cellular response to heat	Biological process	-
ZDHHC21	340481	zinc finger, DHHC-type containing 21	Golgi membrane	Cellular component	-
CYP21A2	1589	cytochrome P450, family 21, subfamily A, polypeptide 2	steroid metabolic process	Biological process	-
Sep-07	989	septin 7	apical plasma membrane	Cellular component	-
SORBS1	10580	sorbin and SH3 domain containing 1	glucose transport	Biological process	-
RPS6KA1	6195	ribosomal protein S6 kinase, 90kDa, polypeptide 1	protein serine/threonine/tyrosine kinase activity	Molecular function	22797923
MUC17	140453	mucin 17, cell surface associated	apical plasma membrane	Cellular component	17990980
KIF20A	10112	kinesin family member 20A	microtubule binding	Molecular function	-
MAP3K10	4294	mitogen-activated protein kinase kinase kinase 10	peptidyl-threonine phosphorylation	Biological process	19801649
CBR1	873	carbonyl reductase 1	drug metabolic process	Biological process	18449627
PRSS16	10279	protease, serine, 16 (thymus)	endosome	Cellular component	10527559
FLOT2	2319	flotillin 2	endosome	Cellular component	20682791
UBE2V1	7335	ubiquitin-conjugating enzyme E2 variant 1	ubiquitin protein ligase activity	Molecular function	-
SYNM	23336	synemin, intermediate filament protein	neurofilament cytoskeleton	Cellular component	14552890
GABRA5	2558	gamma-aminobutyric acid (GABA) A receptor, alpha 5	extracellular ligand-gated ion channel activity	Molecular function	-
ECSIT	51295	ECSIT signalling integrator	signal transducer activity	Molecular function	-
ZFP82	284406	ZFP82 zinc finger protein	metal ion binding	Molecular function	-
EIF4H	7458	eukaryotic translation initiation factor 4H	perinuclear region of cytoplasm	Cellular component	-
ALX3	257	ALX homeobox 3	nucleus	Cellular component	-
ERN1	2081	endoplasmic reticulum to nucleus signaling 1	cellular response to glucose stimulus	Biological process	20103773
HESX1	8820	HESX homeobox 1	protein binding	Molecular function	23455924
ANXA9	8416	annexin A9	protein binding	Molecular function	22841549
IP6K2	51447	inositol hexakisphosphate kinase 2	phosphatidylinositol phosphorylation	Biological process	10574768
P2RX5	5026	purinergic receptor P2X, ligand gated ion channel, 5	nervous system development	Biological process	9414125
GSN	2934	gelsolin	nucleus	Cellular component	23729654
SRCAP	10847	Snf2-related CREBBP activator protein	nucleus	Cellular component	-
TUBE1	51175	tubulin, epsilon 1	protein polymerization	Biological process	-
IGF1R	3480	insulin-like growth factor 1 receptor	protein autophosphorylation	Biological process	11162456
CNOT8	9337	CCR4-NOT transcription complex, subunit 8	metal ion binding	Molecular function	-
CD74	972	CD74 molecule, major histocompatibility complex, class II invariant chain	integral component of lumenal side of endoplasmic reticulum membrane	Cellular component	-
PKP2	5318	plakophilin 2	adherens junction	Cellular component	-
ATCAY	85300	ataxia, cerebellar, Cayman type	mitochondrial membrane	Cellular component	-
PKD2L1	9033	polycystic kidney disease 2-like 1	calcium-activated potassium channel activity	Molecular function	10517637
DAZL	1618	deleted in azoospermia-like	positive regulation of translational initiation	Biological process	16001084
DNAJC21	134218	DnaJ (Hsp40) homolog, subfamily C, member 21	protein folding	Biological process	16952052
DEDD2	162989	death effector domain containing 2	receptor signaling complex scaffold activity	Molecular function	11741985
PSMB4	5692	proteasome (prosome, macropain) subunit, beta type, 4	cytoplasm	Cellular component	-
UBE2W	55284	ubiquitin-conjugating enzyme E2W (putative)	cellular response to misfolded protein	Biological process	-
CENPI	2491	centromere protein I	nucleosome assembly	Biological process	-
EFNA5	1946	ephrin-A5	extracellular region	Cellular component	-
RGS12	6002	regulator of G-protein signaling 12	regulation of catalytic activity	Biological process	9651375
LLGL1	3996	lethal giant larvae homolog 1 (Drosophila)	protein complex assembly	Biological process	7542763
ABCC4	10257	ATP-binding cassette, sub-family C (CFTR/MRP), member 4	integral component of membrane	Cellular component	-
SYT2	127833	synaptotagmin II	regulation of calcium ion-dependent exocytosis	Biological process	-
LEF1	51176	lymphoid enhancer-binding factor 1	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	Molecular function	20360943
CPEB1	64506	cytoplasmic polyadenylation element binding protein 1	regulation of neuronal synaptic plasticity	Biological process	-
GOLPH3	64083	golgi phosphoprotein 3 (coat-protein)	positive regulation of protein secretion	Biological process	23345592
FLT3LG	2323	fms-related tyrosine kinase 3 ligand	extracellular space	Cellular component	-
GHSR	2693	growth hormone secretagogue receptor	positive regulation of insulin-like growth factor receptor signaling pathway	Biological process	-
CXCL12	6387	chemokine (C-X-C motif) ligand 12	response to radiation	Biological process	-
PLIN5	440503	perilipin 5	positive regulation of lipase activity	Biological process	-
PHB	5245	prohibitin	transcription regulatory region DNA binding	Molecular function	18487222
GNAS	2778	GNAS complex locus	tissue homeostasis	Biological process	-
TCF24	100129654	transcription factor 24	regulation of transcription, DNA-templated	Biological process	-
GYS2	2998	glycogen synthase 2 (liver)	cortical actin cytoskeleton	Cellular component	-
CDH13	1012	cadherin 13	endothelial cell migration	Biological process	14729458
ABCD2	225	ATP-binding cassette, sub-family D (ALD), member 2	ATP binding	Molecular function	-
OR51B4	79339	olfactory receptor, family 51, subfamily B, member 4	integral component of membrane	Cellular component	11121057
SLC26A11	284129	solute carrier family 26 (anion exchanger), member 11	anion transmembrane transporter activity	Molecular function	12626430
TLL2	7093	tolloid-like 2	extracellular matrix disassembly	Biological process	-
SOX17	64321	SRY (sex determining region Y)-box 17	endocardium formation	Biological process	-
SLC2A12	154091	solute carrier family 2 (facilitated glucose transporter), member 12	glucose transmembrane transporter activity	Molecular function	-
GATA3	2625	GATA binding protein 3	otic vesicle development	Biological process	-
DACT1	51339	dishevelled-binding antagonist of beta-catenin 1	regulation of protein stability	Biological process	21262972
DENND5B	160518	DENN/MADD domain containing 5B	positive regulation of GTPase activity	Biological process	-
HOXA11	3207	homeobox A11	skeletal system development	Biological process	-
LHX3	8022	LIM homeobox 3	organ morphogenesis	Biological process	10598593
CHAT	1103	choline O-acetyltransferase	neuromuscular synaptic transmission	Biological process	-
GJD3	125111	gap junction protein, delta 3, 31.9kDa	gap junction assembly	Biological process	12154091
PLAUR	5329	plasminogen activator, urokinase receptor	negative regulation of apoptotic process	Biological process	22984561
HEYL	26508	hes-related family bHLH transcription factor with YRPW motif-like	positive regulation of transcription from RNA polymerase II promoter	Biological process	21290414
IGKV2-40	28916	immunoglobulin kappa variable 2-40	Fc-gamma receptor signaling pathway involved in phagocytosis	Biological process	-
EPHB3	2049	EPH receptor B3	urogenital system development	Biological process	-
CBX6	23466	chromobox homolog 6	heterochromatin	Cellular component	-
YWHAH	7533	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta	insulin-like growth factor receptor binding	Molecular function	-
RPS10	6204	ribosomal protein S10	cytoplasm	Cellular component	-
MFSD2B	388931	major facilitator superfamily domain containing 2B	integral component of membrane	Cellular component	-
BBS7	55212	Bardet-Biedl syndrome 7	intracellular transport	Biological process	-
MDM2	4193	MDM2 proto-oncogene, E3 ubiquitin protein ligase	phosphatidylinositol-mediated signaling	Biological process	-
LYN	4067	LYN proto-oncogene, Src family tyrosine kinase	histamine secretion by mast cell	Biological process	-
PKN1	5585	protein kinase N1	hyperosmotic response	Biological process	-
ENDOV	284131	endonuclease V	DNA repair	Biological process	-
SOGA1	140710	suppressor of glucose, autophagy associated 1	negative regulation of gluconeogenesis	Biological process	20813965
GRID2IP	392862	glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein	postsynaptic membrane	Cellular component	-
SPATA7	55812	spermatogenesis associated 7	ciliary basal body	Cellular component	25398945
GABRG3	2567	gamma-aminobutyric acid (GABA) A receptor, gamma 3	ion transmembrane transport	Biological process	-
CELF3	11189	CUGBP, Elav-like family member 3	mRNA splicing, via spliceosome	Biological process	11158314
NR2C2	7182	nuclear receptor subfamily 2, group C, member 2	positive regulation of embryonic development	Biological process	-
P2RX6	9127	purinergic receptor P2X, ligand gated ion channel, 6	identical protein binding	Molecular function	15313628
FBXL7	23194	F-box and leucine-rich repeat protein 7	protein ubiquitination	Biological process	-
MLC1	23209	megalencephalic leukoencephalopathy with subcortical cysts 1	cytoplasm	Cellular component	15892299
MAFB	9935	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B	sequence-specific DNA binding	Molecular function	-
ITGB1	3688	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	viral entry into host cell	Biological process	-
DDX24	57062	DEAD (Asp-Glu-Ala-Asp) box helicase 24	RNA metabolic process	Biological process	10936056
HS3ST6	64711	heparan sulfate (glucosamine) 3-O-sulfotransferase 6	glycosaminoglycan biosynthetic process	Biological process	-
FANCM	57697	Fanconi anemia, complementation group M	DNA repair	Biological process	-
USP4	7375	ubiquitin specific peptidase 4 (proto-oncogene)	spliceosomal tri-snRNP complex assembly	Biological process	20595234
HMGCR	3156	3-hydroxy-3-methylglutaryl-CoA reductase	integral component of membrane	Cellular component	-
ATP1A1	476	ATPase, Na+/K+ transporting, alpha 1 polypeptide	potassium ion import across plasma membrane	Biological process	-
GABPA	2551	GA binding protein transcription factor, alpha subunit 60kDa	nuclear chromatin	Cellular component	22306510
ANKRD33	341405	ankyrin repeat domain 33	negative regulation of transcription regulatory region DNA binding	Biological process	-
NPTN	27020	neuroplastin	cytosol	Cellular component	-
PLA2G1B	5319	phospholipase A2, group IB (pancreas)	bile acid binding	Molecular function	7060561
EIF3K	27335	eukaryotic translation initiation factor 3, subunit K	nucleus	Cellular component	-
NAAA	27163	N-acylethanolamine acid amidase	lipid metabolic process	Biological process	-
HPS4	89781	Hermansky-Pudlak syndrome 4	melanosome	Cellular component	12663659
ANPEP	290	alanyl (membrane) aminopeptidase	integral component of plasma membrane	Cellular component	2564851
TCIRG1	10312	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3	cellular defense response	Biological process	9806637
DEFA4	1669	defensin, alpha 4, corticostatin	antibacterial humoral response	Biological process	15616305
MOV10	4343	Mov10 RISC complex RNA helicase	transcription, DNA-templated	Biological process	-
UNC5C	8633	unc-5 homolog C (C. elegans)	netrin-activated signaling pathway	Biological process	-
SIRT3	23410	sirtuin 3	mitochondrial matrix	Cellular component	-
ARAP1	116985	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1	actin filament reorganization involved in cell cycle	Biological process	11804590
FCN1	2219	ficolin (collagen/fibrinogen domain containing) 1	signaling pattern recognition receptor activity	Molecular function	21037097
SLC38A3	10991	solute carrier family 38, member 3	L-alanine transport	Biological process	10823827
LARP7	51574	La ribonucleoprotein domain family, member 7	cytoplasm	Cellular component	-
PAPPA-AS1	493913	PAPPA antisense RNA 1	cellular_component	Cellular component	-
UNC13A	23025	unc-13 homolog A (C. elegans)	synaptic vesicle docking	Biological process	-
RAB39B	116442	RAB39B, member RAS oncogene family	protein binding	Molecular function	24705354
ADAM18	8749	ADAM metallopeptidase domain 18	metalloendopeptidase activity	Molecular function	-
PSMD7	5713	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	apoptotic process	Biological process	-
ERBB2	2064	erb-b2 receptor tyrosine kinase 2	fibroblast growth factor receptor signaling pathway	Biological process	-
CYP26B1	56603	cytochrome P450, family 26, subfamily B, polypeptide 1	iron ion binding	Molecular function	-
TRIM45	80263	tripartite motif containing 45	intercellular bridge	Cellular component	-
SEC61B	10952	Sec61 beta subunit	epidermal growth factor binding	Molecular function	19602593
MAPK15	225689	mitogen-activated protein kinase 15	MAP kinase activity	Molecular function	11875070
TAP2	6891	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	TAP1 binding	Molecular function	1538751
MCEE	84693	methylmalonyl CoA epimerase	metal ion binding	Molecular function	-
SPIRE2	84501	spire-type actin nucleation factor 2	vesicle-mediated transport	Biological process	-
ZEB1	6935	zinc finger E-box binding homeobox 1	nucleus	Cellular component	20418909
ANXA6	309	annexin A6	ligand-gated ion channel activity	Molecular function	16605264
MYLK	4638	myosin light chain kinase	small GTPase mediated signal transduction	Biological process	-
MTHFD1	4522	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase	oxidation-reduction process	Biological process	-
GABRB2	2561	gamma-aminobutyric acid (GABA) A receptor, beta 2	GABA-A receptor complex	Cellular component	-
CCL11	6356	chemokine (C-C motif) ligand 11	positive regulation of actin filament polymerization	Biological process	19525930
ZNF823	55552	zinc finger protein 823	transcription, DNA-templated	Biological process	-
ASXL1	171023	additional sex combs like transcriptional regulator 1	transcription corepressor activity	Molecular function	-
IL17RB	55540	interleukin 17 receptor B	interleukin-17 receptor activity	Molecular function	-
PNO1	56902	partner of NOB1 homolog (S. cerevisiae)	nucleus	Cellular component	-
RFC2	5982	replication factor C (activator 1) 2, 40kDa	nucleotide-excision repair, DNA gap filling	Biological process	-
GGA2	23062	golgi-associated, gamma adaptin ear containing, ARF binding protein 2	vesicle-mediated transport	Biological process	-
ITGA3	3675	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	plasma membrane	Cellular component	-
FUT2	2524	fucosyltransferase 2 (secretor status included)	fucosyltransferase activity	Molecular function	7876235
ATP2A3	489	ATPase, Ca++ transporting, ubiquitous	platelet dense tubular network membrane	Cellular component	-
ADORA1	134	adenosine A1 receptor	negative regulation of blood pressure	Biological process	-
MRPL30	51263	mitochondrial ribosomal protein L30	mitochondrial inner membrane	Cellular component	-
PNPT1	87178	polyribonucleotide nucleotidyltransferase 1	cytoplasm	Cellular component	-
PDX1	3651	pancreatic and duodenal homeobox 1	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
NRXN3	9369	neurexin 3	signal transduction	Biological process	18923512
MSRA	4482	methionine sulfoxide reductase A	response to oxidative stress	Biological process	-
PCDHA2	56146	protocadherin alpha 2	nervous system development	Biological process	10380929
ELP3	55140	elongator acetyltransferase complex subunit 3	transcription elongation from RNA polymerase II promoter	Biological process	11714725
UGT1A1	54658	UDP glucuronosyltransferase 1 family, polypeptide A1	organ regeneration	Biological process	-
PARK2	5071	parkin RBR E3 ubiquitin protein ligase	negative regulation of actin filament bundle assembly	Biological process	17512523
AHCY	191	adenosylhomocysteinase	xenobiotic metabolic process	Biological process	-
LRP1	4035	low density lipoprotein receptor-related protein 1	beta-amyloid clearance	Biological process	19098903
ZNF160	90338	zinc finger protein 160	transcription, DNA-templated	Biological process	-
ADRA2A	150	adrenoceptor alpha 2A	DNA replication	Biological process	-
RAB7A	7879	RAB7A, member RAS oncogene family	positive regulation of viral process	Biological process	22072966
CRIPAK	285464	cysteine-rich PAK1 inhibitor	cytoplasm	Cellular component	16278681
PAX4	5078	paired box 4	transcription, DNA-templated	Biological process	-
CRIPT	9419	cysteine-rich PDZ-binding protein	protein localization to microtubule	Biological process	-
EZH2	2146	enhancer of zeste 2 polycomb repressive complex 2 subunit	negative regulation of transcription from RNA polymerase II promoter	Biological process	20154697
KHSRP	8570	KH-type splicing regulatory protein	mRNA processing	Biological process	-
BDH2	56898	3-hydroxybutyrate dehydrogenase, type 2	3-hydroxybutyrate dehydrogenase activity	Molecular function	16380372
MYCN	4613	v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog	cartilage condensation	Biological process	-
RBX1	9978	ring-box 1, E3 ubiquitin protein ligase	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	-
CASP8	841	caspase 8, apoptosis-related cysteine peptidase	toll-like receptor signaling pathway	Biological process	-
SLC7A13	157724	solute carrier family 7 (anionic amino acid transporter), member 13	L-alpha-amino acid transmembrane transport	Biological process	-
FCGR1B	2210	Fc fragment of IgG, high affinity Ib, receptor (CD64)	antigen processing and presentation of exogenous peptide antigen via MHC class I	Biological process	-
CHST11	50515	carbohydrate (chondroitin 4) sulfotransferase 11	respiratory gaseous exchange	Biological process	-
MTPN	136319	myotrophin	positive regulation of cardiac muscle hypertrophy	Biological process	10329199
CLK1	1195	CDC-like kinase 1	peptidyl-tyrosine phosphorylation	Biological process	-
PRKCZ	5590	protein kinase C, zeta	cell-cell junction	Cellular component	20332120
MYC	4609	v-myc avian myelocytomatosis viral oncogene homolog	canonical Wnt signaling pathway	Biological process	21533051
GATA6	2627	GATA binding protein 6	lung saccule development	Biological process	-
TRAPPC4	51399	trafficking protein particle complex 4	synaptic vesicle	Cellular component	11018053
PLEKHA1	59338	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	estrogen metabolic process	Biological process	-
PFDN2	5202	prefoldin subunit 2	nucleolus	Cellular component	-
HDAC4	9759	histone deacetylase 4	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
LPCAT3	10162	lysophosphatidylcholine acyltransferase 3	small molecule metabolic process	Biological process	-
PLS1	5357	plastin 1	extracellular exosome	Cellular component	19056867
SLC52A3	113278	solute carrier family 52 (riboflavin transporter), member 3	water-soluble vitamin metabolic process	Biological process	-
WNT2B	7482	wingless-type MMTV integration site family, member 2B	positive regulation of canonical Wnt signaling pathway	Biological process	11741304
PMPCA	23203	peptidase (mitochondrial processing) alpha	extracellular space	Cellular component	22664934
ADGRE5	976	adhesion G protein-coupled receptor E5	integral component of plasma membrane	Cellular component	8955192
RNF182	221687	ring finger protein 182	cytoplasm	Cellular component	18298843
ZNF367	195828	zinc finger protein 367	nucleoplasm	Cellular component	-
SLC35F6	54978	solute carrier family 35, member F6	transport	Biological process	-
TGS1	96764	trimethylguanosine synthase 1	nucleus	Cellular component	-
PARP1	142	poly (ADP-ribose) polymerase 1	regulation of growth rate	Biological process	-
GBP7	388646	guanylate binding protein 7	GTPase activity	Molecular function	-
SLC39A14	23516	solute carrier family 39 (zinc transporter), member 14	transmembrane transport	Biological process	-
MAN1A2	10905	mannosidase, alpha, class 1A, member 2	Golgi apparatus	Cellular component	-
EFNA1	1942	ephrin-A1	ephrin receptor binding	Molecular function	15777695
NRG1	3084	neuregulin 1	cell proliferation	Biological process	11389077
AGO2	27161	argonaute RISC catalytic component 2	mRNA binding	Molecular function	-
FPGS	2356	folylpolyglutamate synthase	cytoplasm	Cellular component	1409616
GLRX	2745	glutaredoxin (thioltransferase)	positive regulation of sodium ion transmembrane transporter activity	Biological process	19542013
PNKP	11284	polynucleotide kinase 3'-phosphatase	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity	Molecular function	10446193
HELZ2	85441	helicase with zinc finger 2, transcriptional coactivator	nucleoplasm	Cellular component	-
GSTM3	2947	glutathione S-transferase mu 3 (brain)	enzyme binding	Molecular function	8373352
GNB2	2783	guanine nucleotide binding protein (G protein), beta polypeptide 2	cellular response to glucagon stimulus	Biological process	-
TMEM100	55273	transmembrane protein 100	Notch signaling pathway	Biological process	-
HDAC11	79885	histone deacetylase 11	histone deacetylase complex	Cellular component	11948178
GCK	2645	glucokinase (hexokinase 4)	positive regulation of phosphorylation	Biological process	-
CRABP2	1382	cellular retinoic acid binding protein 2	retinol binding	Molecular function	-
NFIB	4781	nuclear factor I/B	negative regulation of epithelial cell proliferation involved in lung morphogenesis	Biological process	-
RPS9	6203	ribosomal protein S9	extracellular exosome	Cellular component	20458337
AGPAT4	56895	1-acylglycerol-3-phosphate O-acyltransferase 4	integral component of membrane	Cellular component	-
DRG1	4733	developmentally regulated GTP binding protein 1	identical protein binding	Molecular function	23711155
ANP32B	10541	acidic (leucine-rich) nuclear phosphoprotein 32 family, member B	nucleolus	Cellular component	9285060
DAXX	1616	death-domain associated protein	heterochromatin	Cellular component	-
CKS1B	1163	CDC28 protein kinase regulatory subunit 1B	regulation of cyclin-dependent protein serine/threonine kinase activity	Biological process	8601310
ADA	100	adenosine deaminase	regulation of cell-cell adhesion mediated by integrin	Biological process	11772392
FBXO33	254170	F-box protein 33	protein ubiquitination	Biological process	-
DUSP1	1843	dual specificity phosphatase 1	response to testosterone	Biological process	-
HNRNPAB	3182	heterogeneous nuclear ribonucleoprotein A/B	nucleus	Cellular component	-
UBE2I	7329	ubiquitin-conjugating enzyme E2I	enzyme binding	Molecular function	17087506
PPP3CA	5530	protein phosphatase 3, catalytic subunit, alpha isozyme	protein import into nucleus	Biological process	-
KIF18B	146909	kinesin family member 18B	nucleoplasm	Cellular component	-
TFAP2B	7021	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	negative regulation of transcription from RNA polymerase II promoter	Biological process	7559606
CLEC7A	64581	C-type lectin domain family 7, member A	defense response to protozoan	Biological process	11567029
UPK3BL	100134938	uroplakin 3B-like	integral component of membrane	Cellular component	-
CYP1B1	1545	cytochrome P450, family 1, subfamily B, polypeptide 1	omega-hydroxylase P450 pathway	Biological process	-
WWC1	23286	WW and C2 domain containing 1	transcription coactivator activity	Molecular function	16684779
HRAS	3265	Harvey rat sarcoma viral oncogene homolog	negative regulation of gene expression	Biological process	23027131
COG1	9382	component of oligomeric golgi complex 1	protein transport	Biological process	-
STK39	27347	serine threonine kinase 39	ATP binding	Molecular function	-
HHEX	3087	hematopoietically expressed homeobox	gall bladder development	Biological process	-
CCBL1	883	cysteine conjugate-beta lyase, cytoplasmic	L-phenylalanine catabolic process	Biological process	-
AFP	174	alpha-fetoprotein	SMAD protein signal transduction	Biological process	-
USP28	57646	ubiquitin specific peptidase 28	cysteine-type endopeptidase activity	Molecular function	-
GJA8	2703	gap junction protein, alpha 8, 50kDa	lens development in camera-type eye	Biological process	-
GALNT2	2590	polypeptide N-acetylgalactosaminyltransferase 2	immunoglobulin biosynthetic process	Biological process	12438318
BEND6	221336	BEN domain containing 6	nucleus	Cellular component	-
PHF1	5252	PHD finger protein 1	microtubule organizing center	Cellular component	-
ZFP36	7538	ZFP36 ring finger protein	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	Biological process	10330172
NTF4	4909	neurotrophin 4	innervation	Biological process	-
TEK	7010	TEK tyrosine kinase, endothelial	integral component of plasma membrane	Cellular component	19689429
MED12	9968	mediator complex subunit 12	Schwann cell development	Biological process	-
ABCA2	20	ATP-binding cassette, sub-family A (ABC1), member 2	transport	Biological process	11178988
TUBB1	81027	tubulin, beta 1 class VI	protein folding	Biological process	-
RAD54L2	23132	RAD54-like 2 (S. cerevisiae)	transcription cofactor activity	Molecular function	-
Sep-02	4735	septin 2	nucleolus	Cellular component	-
COLGALT1	79709	collagen beta(1-O)galactosyltransferase 1	extracellular matrix organization	Biological process	-
KCNA2	3737	potassium channel, voltage gated shaker related subfamily A, member 2	outward rectifier potassium channel activity	Molecular function	-
THTPA	79178	thiamine triphosphatase	magnesium ion binding	Molecular function	-
PBX4	80714	pre-B-cell leukemia homeobox 4	XY body	Cellular component	-
BLMH	642	bleomycin hydrolase	nucleus	Cellular component	-
PSMB2	5690	proteasome (prosome, macropain) subunit, beta type, 2	positive regulation of canonical Wnt signaling pathway	Biological process	-
CAND2	23066	cullin-associated and neddylation-dissociated 2 (putative)	protein ubiquitination	Biological process	-
ZFPM1	161882	zinc finger protein, FOG family member 1	blood coagulation	Biological process	-
BMP6	654	bone morphogenetic protein 6	transforming growth factor beta receptor binding	Molecular function	-
PTK2B	2185	protein tyrosine kinase 2 beta	nucleoplasm	Cellular component	-
GGTLC3	728226	gamma-glutamyltransferase light chain 3	gamma-glutamyltransferase activity	Molecular function	18357469
GJA5	2702	gap junction protein, alpha 5, 40kDa	negative regulation of glomerular filtration	Biological process	-
NKX2-5	1482	NK2 homeobox 5	DNA binding	Molecular function	9858576
NPY2R	4887	neuropeptide Y receptor Y2	plasma membrane	Cellular component	-
DISP1	84976	dispatched homolog 1 (Drosophila)	protein binding	Molecular function	25416956
TOMM22	56993	translocase of outer mitochondrial membrane 22 homolog (yeast)	protein transmembrane transporter activity	Molecular function	15644312
TBK1	29110	TANK-binding kinase 1	endosome membrane	Cellular component	-
FGD3	89846	FYVE, RhoGEF and PH domain containing 3	cytoskeleton organization	Biological process	-
REEP1	65055	receptor accessory protein 1	mitochondrial membrane	Cellular component	-
ADRA2B	151	adrenoceptor alpha 2B	plasma membrane	Cellular component	-
USF2	7392	upstream transcription factor 2, c-fos interacting	lactation	Biological process	-
HTT	3064	huntingtin	dendrite	Cellular component	7748555
LEP	3952	leptin	response to dietary excess	Biological process	-
FBXO25	26260	F-box protein 25	protein binding	Molecular function	20473970
GNA13	10672	guanine nucleotide binding protein (G protein), alpha 13	GTPase activity	Molecular function	-
CRHR1	1394	corticotropin releasing hormone receptor 1	corticotropin-releasing hormone receptor activity	Molecular function	-
PIK3CD	5293	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	phospholipid metabolic process	Biological process	-
CTRB1	1504	chymotrypsinogen B1	vitamin metabolic process	Biological process	-
NIPBL	25836	Nipped-B homolog (Drosophila)	embryonic digestive tract morphogenesis	Biological process	19242925
SCEL	8796	sciellin	zinc ion binding	Molecular function	-
FZD1	8321	frizzled class receptor 1	canonical Wnt signaling pathway involved in osteoblast differentiation	Biological process	20039315
APOL1	8542	apolipoprotein L, 1	very-low-density lipoprotein particle	Cellular component	17154273
KCNJ8	3764	potassium channel, inwardly rectifying subfamily J, member 8	ATP-activated inward rectifier potassium channel activity	Molecular function	-
TRIM59	286827	tripartite motif containing 59	innate immune response	Biological process	-
OR52E5	390082	olfactory receptor, family 52, subfamily E, member 5	G-protein coupled receptor signaling pathway	Biological process	-
RAD18	56852	RAD18 E3 ubiquitin protein ligase	replication fork	Cellular component	18363965
EIF4E	1977	eukaryotic translation initiation factor 4E	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	Biological process	-
KIAA1715	80856	KIAA1715	endoplasmic reticulum tubular network organization	Biological process	-
HLA-C	3107	major histocompatibility complex, class I, C	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	Biological process	-
PSMA6	5687	proteasome (prosome, macropain) subunit, alpha type, 6	RNA binding	Molecular function	7681138
EIF3F	8665	eukaryotic translation initiation factor 3, subunit F	formation of translation preinitiation complex	Biological process	-
KPNA2	3838	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	nuclear localization sequence binding	Molecular function	17324944
ZNF107	51427	zinc finger protein 107	nucleus	Cellular component	-
PCDH8	5100	protocadherin 8	integral component of plasma membrane	Cellular component	9787079
OBSCN	84033	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	Rho guanyl-nucleotide exchange factor activity	Molecular function	-
CRTAM	56253	cytotoxic and regulatory T cell molecule	plasma membrane	Cellular component	-
TMEM2	23670	transmembrane protein 2	integral component of membrane	Cellular component	-
LTBP3	4054	latent transforming growth factor beta binding protein 3	calcium ion binding	Molecular function	-
RIPK2	8767	receptor-interacting serine-threonine kinase 2	neurotrophin TRK receptor signaling pathway	Biological process	-
GSTA4	2941	glutathione S-transferase alpha 4	protein binding	Molecular function	25416956
GPD2	2820	glycerol-3-phosphate dehydrogenase 2 (mitochondrial)	oxidation-reduction process	Biological process	-
VCP	7415	valosin containing protein	double-strand break repair	Biological process	10855792
ADGRV1	84059	adhesion G protein-coupled receptor V1	periciliary membrane compartment	Cellular component	-
RPTOR	57521	regulatory associated protein of MTOR, complex 1	nucleoplasm	Cellular component	-
EP300	2033	E1A binding protein p300	nucleus	Cellular component	12929931
MLF1	4291	myeloid leukemia factor 1	DNA binding	Molecular function	-
TUBB6	84617	tubulin, beta 6 class V	molecular_function	Molecular function	-
MCL1	4170	myeloid cell leukemia 1	protein heterodimerization activity	Molecular function	10837489
TMEM173	340061	transmembrane protein 173	positive regulation of transcription from RNA polymerase II promoter	Biological process	18818105
ARSJ	79642	arylsulfatase family, member J	cellular protein metabolic process	Biological process	-
GNAS	2778	GNAS complex locus	positive regulation of cAMP-mediated signaling	Biological process	12391161
ACTR5	79913	ARP5 actin-related protein 5 homolog (yeast)	regulation of transcription, DNA-templated	Biological process	-
TBC1D20	128637	TBC1 domain family, member 20	positive regulation of GTPase activity	Biological process	17684057
FAM178A	55719	family with sequence similarity 178, member A	intracellular membrane-bounded organelle	Cellular component	-
P2RY1	5028	purinergic receptor P2Y, G-protein coupled, 1	positive regulation of inositol trisphosphate biosynthetic process	Biological process	-
RALGAPA1	253959	Ral GTPase activating protein, alpha subunit 1 (catalytic)	regulation of transcription, DNA-templated	Biological process	-
C3	718	complement component 3	extracellular region	Cellular component	-
MSR1	4481	macrophage scavenger receptor 1	lipoprotein transport	Biological process	-
KIAA0101	9768	KIAA0101	regulation of cell cycle	Biological process	21628590
TMEM100	55273	transmembrane protein 100	perinuclear region of cytoplasm	Cellular component	22783020
FAS	355	Fas cell surface death receptor	regulation of extrinsic apoptotic signaling pathway via death domain receptors	Biological process	-
CDC42EP5	148170	CDC42 effector protein (Rho GTPase binding) 5	plasma membrane	Cellular component	-
MYO1C	4641	myosin IC	positive regulation of vascular endothelial growth factor signaling pathway	Biological process	23262137
AP2A1	160	adaptor-related protein complex 2, alpha 1 subunit	cytosol	Cellular component	-
FUT1	2523	fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)	fucosylation	Biological process	-
CLC	1178	Charcot-Leyden crystal galectin	carbohydrate binding	Molecular function	-
ISY1	57461	ISY1 splicing factor homolog (S. cerevisiae)	poly(A) RNA binding	Molecular function	22658674
AR	367	androgen receptor	cytosol	Cellular component	-
TYROBP	7305	TYRO protein tyrosine kinase binding protein	neutrophil activation involved in immune response	Biological process	-
JAG2	3714	jagged 2	regulation of cell migration	Biological process	11549580
TRMU	55687	tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase	tRNA binding	Molecular function	-
PDHA1	5160	pyruvate dehydrogenase (lipoamide) alpha 1	mitochondrial matrix	Cellular component	-
GSK3A	2931	glycogen synthase kinase 3 alpha	negative regulation of glycogen biosynthetic process	Biological process	19366350
LAMP5	24141	lysosomal-associated membrane protein family, member 5	dendrite	Cellular component	-
SLC2A4	6517	solute carrier family 2 (facilitated glucose transporter), member 4	glucose import	Biological process	11742412
HSPB1	3315	heat shock 27kDa protein 1	response to unfolded protein	Biological process	1560006
SSX2IP	117178	synovial sarcoma, X breakpoint 2 interacting protein	nucleus	Cellular component	-
OPRM1	4988	opioid receptor, mu 1	protein domain specific binding	Molecular function	-
PML	5371	promyelocytic leukemia	negative regulation of telomere maintenance via telomerase	Biological process	19567472
STRA6	64220	stimulated by retinoic acid 6	diaphragm development	Biological process	17273977
APOBEC3F	200316	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F	cytoplasm	Cellular component	16527742
EGFR	1956	epidermal growth factor receptor	plasma membrane	Cellular component	-
BCL3	602	B-cell CLL/lymphoma 3	I-kappaB kinase/NF-kappaB signaling	Biological process	8196632
ADCK2	90956	aarF domain containing kinase 2	ATP binding	Molecular function	-
SIRPG	55423	signal-regulatory protein gamma	protein binding	Molecular function	15383453
RAB5C	5878	RAB5C, member RAS oncogene family	intracellular protein transport	Biological process	-
LIMS2	55679	LIM and senescent cell antigen-like domains 2	negative regulation of hepatocyte proliferation	Biological process	-
FGFR1	2260	fibroblast growth factor receptor 1	positive regulation of phosphatidylinositol 3-kinase signaling	Biological process	15863030
ARHGDIA	396	Rho GDP dissociation inhibitor (GDI) alpha	regulation of protein localization	Biological process	-
CYP4F2	8529	cytochrome P450, family 4, subfamily F, polypeptide 2	iron ion binding	Molecular function	-
TYMP	1890	thymidine phosphorylase	pyrimidine nucleoside salvage	Biological process	-
TTLL9	164395	tubulin tyrosine ligase-like family member 9	cellular protein modification process	Biological process	-
SMG1	23049	SMG1 phosphatidylinositol 3-kinase-related kinase	metal ion binding	Molecular function	-
C2orf66	401027	chromosome 2 open reading frame 66	extracellular region	Cellular component	-
CRIPT	9419	cysteine-rich PDZ-binding protein	dendritic shaft	Cellular component	-
CREG2	200407	cellular repressor of E1A-stimulated genes 2	oxidation-reduction process	Biological process	-
IFI27	3429	interferon, alpha-inducible protein 27	regulation of protein export from nucleus	Biological process	22427340
FSHR	2492	follicle stimulating hormone receptor	activation of adenylate cyclase activity	Biological process	-
APC2	10297	adenomatosis polyposis coli 2	negative regulation of catenin import into nucleus	Biological process	10021369
UBA52	7311	ubiquitin A-52 residue ribosomal protein fusion product 1	positive regulation of canonical Wnt signaling pathway	Biological process	-
NADSYN1	55191	NAD synthetase 1	water-soluble vitamin metabolic process	Biological process	-
PLCD1	5333	phospholipase C, delta 1	calcium ion binding	Molecular function	-
RNGTT	8732	RNA guanylyltransferase and 5'-phosphatase	RNA guanylyltransferase activity	Molecular function	21636784
KAT8	84148	K(lysine) acetyltransferase 8	MLL1 complex	Cellular component	15960975
XPA	7507	xeroderma pigmentosum, complementation group A	intercellular bridge	Cellular component	-
CYB561	1534	cytochrome b561	integral component of membrane	Cellular component	7559396
GHRL	51738	ghrelin/obestatin prepropeptide	protein binding	Molecular function	25416956
CD28	940	CD28 molecule	innate immune response	Biological process	-
RASA3	22821	RAS p21 protein activator 3	signal transduction	Biological process	7637787
BOC	91653	BOC cell adhesion associated, oncogene regulated	activation of mitophagy in response to mitochondrial depolarization	Biological process	22020285
UCP3	7352	uncoupling protein 3 (mitochondrial, proton carrier)	integral component of membrane	Cellular component	-
MRPS6	64968	mitochondrial ribosomal protein S6	protein binding	Molecular function	22458338
NHLRC1	378884	NHL repeat containing E3 ubiquitin protein ligase 1	glucose metabolic process	Biological process	-
VAT1L	57687	vesicle amine transport 1-like	protein binding	Molecular function	25416956
RAB8B	51762	RAB8B, member RAS oncogene family	protein import into peroxisome membrane	Biological process	18346465
ZNF322	79692	zinc finger protein 322	transcription, DNA-templated	Biological process	-
IFT57	55081	intraflagellar transport 57	cilium assembly	Biological process	-
PML	5371	promyelocytic leukemia	positive regulation of extrinsic apoptotic signaling pathway	Biological process	21803845
PPEF2	5470	protein phosphatase, EF-hand calcium binding domain 2	negative regulation of peptidyl-threonine phosphorylation	Biological process	20674765
GSK3B	2932	glycogen synthase kinase 3 beta	fat cell differentiation	Biological process	-
NUP43	348995	nucleoporin 43kDa	mitotic nuclear division	Biological process	-
AIFM2	84883	apoptosis-inducing factor, mitochondrion-associated, 2	electron-transferring-flavoprotein dehydrogenase activity	Molecular function	15958387
PRIM2	5558	primase, DNA, polypeptide 2 (58kDa)	DNA strand elongation involved in DNA replication	Biological process	-
ATP1B1	481	ATPase, Na+/K+ transporting, beta 1 polypeptide	sarcolemma	Cellular component	-
STRADA	92335	STE20-related kinase adaptor alpha	cell migration	Biological process	-
TMBIM6	7009	transmembrane BAX inhibitor motif containing 6	ubiquitin protein ligase binding	Molecular function	21068390
APOF	319	apolipoprotein F	cholesterol binding	Molecular function	6816269
FOXC1	2296	forkhead box C1	mesenchymal cell development	Biological process	-
EP400	57634	E1A binding protein p400	histone H2A acetylation	Biological process	14966270
GARS	2617	glycyl-tRNA synthetase	ATP binding	Molecular function	-
MBD3	53615	methyl-CpG binding domain protein 3	nucleoplasm	Cellular component	-
FMNL3	91010	formin-like 3	regulation of cell shape	Biological process	21834987
OR51E2	81285	olfactory receptor, family 51, subfamily E, member 2	G-protein coupled receptor signaling pathway	Biological process	-
SHH	6469	sonic hedgehog	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
CDK2	1017	cyclin-dependent kinase 2	G2/M transition of mitotic cell cycle	Biological process	-
APH1B	83464	APH1B gamma secretase subunit	protein processing	Biological process	12297508
WNT7B	7477	wingless-type MMTV integration site family, member 7B	homeostatic process	Biological process	-
FXYD7	53822	FXYD domain containing ion transport regulator 7	sodium channel regulator activity	Molecular function	-
OR2L2	26246	olfactory receptor, family 2, subfamily L, member 2	sensory perception of smell	Biological process	-
KCNS3	3790	potassium voltage-gated channel, modifier subfamily S, member 3	integral component of membrane	Cellular component	-
OR2D2	120776	olfactory receptor, family 2, subfamily D, member 2	sensory perception of smell	Biological process	9787077
PAFAH2	5051	platelet-activating factor acetylhydrolase 2, 40kDa	negative regulation of apoptotic process	Biological process	-
UBE2S	27338	ubiquitin-conjugating enzyme E2S	ubiquitin protein ligase binding	Molecular function	-
EIF3A	8661	eukaryotic translation initiation factor 3, subunit A	membrane	Cellular component	19946888
SFTPD	6441	surfactant protein D	endocytic vesicle	Cellular component	10485905
CYP1B1	1545	cytochrome P450, family 1, subfamily B, polypeptide 1	blood vessel morphogenesis	Biological process	-
GCLC	2729	glutamate-cysteine ligase, catalytic subunit	cellular nitrogen compound metabolic process	Biological process	-
RNF4	6047	ring finger protein 4	identical protein binding	Molecular function	24714598
TMF1	7110	TATA element modulatory factor 1	nucleus	Cellular component	-
PRDM5	11107	PR domain containing 5	histone H3-K9 methylation	Biological process	17636019
NCR2	9436	natural cytotoxicity triggering receptor 2	transmembrane signaling receptor activity	Molecular function	10049942
RAB39B	116442	RAB39B, member RAS oncogene family	myosin V binding	Molecular function	24006491
SGSM1	129049	small G protein signaling modulator 1	protein binding	Molecular function	25416956
SDC2	6383	syndecan 2	ephrin receptor signaling pathway	Biological process	-
MIF	4282	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	cell aging	Biological process	-
USH2A	7399	Usher syndrome 2A (autosomal recessive, mild)	response to stimulus	Biological process	-
VGLL1	51442	vestigial-like family member 1	transcription, DNA-templated	Biological process	-
TUBA1B	10376	tubulin, alpha 1b	protein folding	Biological process	-
ANKS1A	23294	ankyrin repeat and sterile alpha motif domain containing 1A	cytoplasm	Cellular component	-
TRIM32	22954	tripartite motif containing 32	positive regulation of type I interferon production	Biological process	-
FGF3	2248	fibroblast growth factor 3	epidermal growth factor receptor signaling pathway	Biological process	-
PRKCQ	5588	protein kinase C, theta	blood coagulation	Biological process	-
FOXA1	3169	forkhead box A1	positive regulation of mitotic cell cycle	Biological process	16087863
RAB3A	5864	RAB3A, member RAS oncogene family	clathrin-sculpted acetylcholine transport vesicle membrane	Cellular component	-
UBA52	7311	ubiquitin A-52 residue ribosomal protein fusion product 1	cellular protein modification process	Biological process	2581967
ADRB2	154	adrenoceptor beta 2, surface	activation of mitophagy in response to mitochondrial depolarization	Biological process	22020285
KIF11	3832	kinesin family member 11	microtubule-based movement	Biological process	-
BBC3	27113	BCL2 binding component 3	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	Biological process	22013210
RUVBL2	10856	RuvB-like AAA ATPase 2	negative regulation of estrogen receptor binding	Biological process	23637611
PSMA4	5685	proteasome (prosome, macropain) subunit, alpha type, 4	intracellular membrane-bounded organelle	Cellular component	-
PRIM2	5558	primase, DNA, polypeptide 2 (58kDa)	DNA binding	Molecular function	-
CYP1B1	1545	cytochrome P450, family 1, subfamily B, polypeptide 1	negative regulation of cell adhesion mediated by integrin	Biological process	-
NOG	9241	noggin	embryonic skeletal joint morphogenesis	Biological process	16151340
FRAT2	23401	frequently rearranged in advanced T-cell lymphomas 2	molecular_function	Molecular function	-
MVP	9961	major vault protein	cytoplasm	Cellular component	-
FOXO1	2308	forkhead box O1	anatomical structure morphogenesis	Biological process	-
GUCY2C	2984	guanylate cyclase 2C	intracellular signal transduction	Biological process	-
SLC10A1	6554	solute carrier family 10 (sodium/bile acid cotransporter), member 1	bile acid:sodium symporter activity	Molecular function	-
NRK	203447	Nik related kinase	parturition	Biological process	-
YAP1	10413	Yes-associated protein 1	positive regulation of organ growth	Biological process	-
RHOA	387	ras homolog family member A	apical junction complex	Cellular component	20974804
GAGE7	2579	G antigen 7	biological_process	Biological process	-
RASD1	51655	RAS, dexamethasone-induced 1	perinuclear region of cytoplasm	Cellular component	-
ZNF354B	117608	zinc finger protein 354B	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
CRHR1	1394	corticotropin releasing hormone receptor 1	general adaptation syndrome, behavioral process	Biological process	-
CCR10	2826	chemokine (C-C motif) receptor 10	G-protein coupled receptor signaling pathway	Biological process	-
ZNF761	388561	zinc finger protein 761	regulation of transcription, DNA-templated	Biological process	-
GLB1	2720	galactosidase, beta 1	lysosomal lumen	Cellular component	-
ARHGEF26	26084	Rho guanine nucleotide exchange factor (GEF) 26	endothelial cell morphogenesis	Biological process	-
UBR7	55148	ubiquitin protein ligase E3 component n-recognin 7 (putative)	zinc ion binding	Molecular function	-
SYNE3	161176	spectrin repeat containing, nuclear envelope family member 3	rough endoplasmic reticulum	Cellular component	-
MLH3	27030	mutL homolog 3	ATPase activity	Molecular function	-
EXOC2	55770	exocyst complex component 2	organelle organization	Biological process	-
CACNA1C	775	calcium channel, voltage-dependent, L type, alpha 1C subunit	caveolar macromolecular signaling complex	Cellular component	-
PTK2B	2185	protein tyrosine kinase 2 beta	response to hypoxia	Biological process	-
ASCL1	429	achaete-scute family bHLH transcription factor 1	carotid body glomus cell differentiation	Biological process	-
TDRD9	122402	tudor domain containing 9	cell differentiation	Biological process	-
APOE	348	apolipoprotein E	high-density lipoprotein particle remodeling	Biological process	12401887
VAMP8	8673	vesicle-associated membrane protein 8	cytosol	Cellular component	22589474
DRD2	1813	dopamine receptor D2	dendritic spine	Cellular component	-
IFNL1	282618	interferon, lambda 1	receptor binding	Molecular function	12483210
PTGER4	5734	prostaglandin E receptor 4 (subtype EP4)	response to mechanical stimulus	Biological process	21723865
NDE1	54820	nudE neurodevelopment protein 1	microtubule nucleation	Biological process	-
TNNI1	7135	troponin I type 1 (skeletal, slow)	troponin complex	Cellular component	-
TAS2R7	50837	taste receptor, type 2, member 7	detection of chemical stimulus involved in sensory perception of bitter taste	Biological process	20022913
USP47	55031	ubiquitin specific peptidase 47	negative regulation of transcription, DNA-templated	Biological process	19966869
IL1RN	3557	interleukin 1 receptor antagonist	extracellular space	Cellular component	10443688
RPS4X	6191	ribosomal protein S4, X-linked	extracellular exosome	Cellular component	20458337
GJA1	2697	gap junction protein, alpha 1, 43kDa	connexin binding	Molecular function	-
UBA52	7311	ubiquitin A-52 residue ribosomal protein fusion product 1	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Biological process	-
PITPNC1	26207	phosphatidylinositol transfer protein, cytoplasmic 1	phospholipid transport	Biological process	10531358
TNFAIP8	25816	tumor necrosis factor, alpha-induced protein 8	defense response to Gram-positive bacterium	Biological process	-
CIB1	10519	calcium and integrin binding 1 (calmyrin)	negative regulation of cell proliferation	Biological process	21264284
MRPL47	57129	mitochondrial ribosomal protein L47	mitochondrial translation	Biological process	-
NRXN1	9378	neurexin 1	cerebellar granule cell differentiation	Biological process	-
PPP1R15A	23645	protein phosphatase 1, regulatory subunit 15A	cytoplasm	Cellular component	21518769
MIP	4284	major intrinsic protein of lens fiber	plasma membrane	Cellular component	-
USP17L6P	391622	ubiquitin specific peptidase 17-like family member 6, pseudogene	cytoplasm	Cellular component	-
CORO7	79585	coronin 7	Golgi apparatus	Cellular component	-
VAV2	7410	vav 2 guanine nucleotide exchange factor	cell migration	Biological process	-
SQSTM1	8878	sequestosome 1	negative regulation of apoptotic process	Biological process	-
BLM	641	Bloom syndrome, RecQ helicase-like	regulation of binding	Biological process	-
CLVS1	157807	clavesin 1	clathrin-coated vesicle	Cellular component	-
SRSF7	6432	serine/arginine-rich splicing factor 7	negative regulation of mRNA splicing, via spliceosome	Biological process	15009664
NUF2	83540	NUF2, NDC80 kinetochore complex component	chromosome, centromeric region	Cellular component	11266451
CNTN1	1272	contactin 1	positive regulation of sodium ion transport	Biological process	-
PTPRG	5793	protein tyrosine phosphatase, receptor type, G	transmembrane receptor protein tyrosine phosphatase activity	Molecular function	8382771
LPCAT3	10162	lysophosphatidylcholine acyltransferase 3	phospholipid metabolic process	Biological process	-
CDHR1	92211	cadherin-related family member 1	photoreceptor outer segment membrane	Cellular component	-
DDIT3	1649	DNA-damage-inducible transcript 3	CHOP-ATF3 complex	Cellular component	8622660
ABCC4	10257	ATP-binding cassette, sub-family C (CFTR/MRP), member 4	plasma membrane	Cellular component	-
FBXL21	26223	F-box and leucine-rich repeat protein 21 (gene/pseudogene)	protein ubiquitination	Biological process	10531035
CASR	846	calcium-sensing receptor	calcium ion import	Biological process	20846291
RAB24	53917	RAB24, member RAS oncogene family	mitochondrion	Cellular component	-
NRXN1	9378	neurexin 1	cell adhesion molecule binding	Molecular function	-
OLFM4	10562	olfactomedin 4	extracellular exosome	Cellular component	19056867
TOM1L1	10040	target of myb1 (chicken)-like 1	SH3 domain binding	Molecular function	-
ADAR	103	adenosine deaminase, RNA-specific	definitive hemopoiesis	Biological process	-
PAFAH1B3	5050	platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)	1-alkyl-2-acetylglycerophosphocholine esterase activity	Molecular function	-
SRCAP	10847	Snf2-related CREBBP activator protein	protein binding	Molecular function	10702287
DYNLL2	140735	dynein, light chain, LC8-type 2	cytosol	Cellular component	-
FGF6	2251	fibroblast growth factor 6	growth factor activity	Molecular function	-
P2RX7	5027	purinergic receptor P2X, ligand gated ion channel, 7	apoptotic signaling pathway	Biological process	-
CYP11A1	1583	cytochrome P450, family 11, subfamily A, polypeptide 1	cellular response to follicle-stimulating hormone stimulus	Biological process	-
EPHA10	284656	EPH receptor A10	integral component of plasma membrane	Cellular component	-
ATRX	546	alpha thalassemia/mental retardation syndrome X-linked	DNA methylation	Biological process	10742099
NLN	57486	neurolysin (metallopeptidase M3 family)	mitochondrial intermembrane space	Cellular component	-
CIC	23152	capicua transcriptional repressor	transcription, DNA-templated	Biological process	-
RTKN	6242	rhotekin	Rho protein signal transduction	Biological process	15480428
MYL3	4634	myosin, light chain 3, alkali; ventricular, skeletal, slow	I band	Cellular component	16675844
RFWD2	64326	ring finger and WD repeat domain 2, E3 ubiquitin protein ligase	protein binding	Molecular function	19805145
IFNA1	3439	interferon, alpha 1	B cell proliferation	Biological process	-
BPIFB4	149954	BPI fold containing family B, member 4	cytoplasm	Cellular component	-
EIF4G1	1981	eukaryotic translation initiation factor 4 gamma, 1	translation initiation factor activity	Molecular function	8961935
EFNB2	1948	ephrin-B2	axon guidance	Biological process	-
ERO1L	30001	ERO1-like (S. cerevisiae)	brown fat cell differentiation	Biological process	-
IL4	3565	interleukin 4	positive regulation of interleukin-10 production	Biological process	-
MTMR2	8898	myotubularin related protein 2	extracellular exosome	Cellular component	18570454
PROK2	60675	prokineticin 2	chemotaxis	Biological process	12604792
C19orf40	91442	chromosome 19 open reading frame 40	Fanconi anaemia nuclear complex	Cellular component	20347428
FGF5	2250	fibroblast growth factor 5	cell proliferation	Biological process	3211147
PNPLA7	375775	patatin-like phospholipase domain containing 7	mitochondrial membrane	Cellular component	-
ADAMTSL4	54507	ADAMTS-like 4	cellular protein metabolic process	Biological process	-
ZSCAN5A	79149	zinc finger and SCAN domain containing 5A	transcription from RNA polymerase II promoter	Biological process	-
PRKD2	25865	protein kinase D2	positive regulation of transcription from RNA polymerase II promoter	Biological process	18059339
POLR3B	55703	polymerase (RNA) III (DNA directed) polypeptide B	gene expression	Biological process	-
KDM1A	23028	lysine (K)-specific demethylase 1A	nuclear chromatin	Cellular component	20833138
ICMT	23463	isoprenylcysteine carboxyl methyltransferase	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity	Molecular function	-
RPS15A	6210	ribosomal protein S15a	viral transcription	Biological process	-
ABL1	25	ABL proto-oncogene 1, non-receptor tyrosine kinase	response to oxidative stress	Biological process	17626041
ZNF784	147808	zinc finger protein 784	regulation of transcription, DNA-templated	Biological process	-
MRPL1	65008	mitochondrial ribosomal protein L1	mitochondrial translational initiation	Biological process	-
CHMP2B	25978	charged multivesicular body protein 2B	extracellular exosome	Cellular component	19056867
TBXA2R	6915	thromboxane A2 receptor	positive regulation of smooth muscle contraction	Biological process	-
ZNF615	284370	zinc finger protein 615	transcription, DNA-templated	Biological process	-
GIMAP5	55340	GTPase, IMAP family member 5	positive regulation of natural killer cell cytokine production	Biological process	-
RBCK1	10616	RanBP-type and C3HC4-type zinc finger containing 1	T cell receptor signaling pathway	Biological process	20005846
CREBL2	1389	cAMP responsive element binding protein-like 2	positive regulation of peptidyl-serine phosphorylation	Biological process	-
PLOD3	8985	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3	protein binding	Molecular function	16189514
DDX23	9416	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23	RNA splicing	Biological process	-
MAML3	55534	mastermind-like 3 (Drosophila)	transcription initiation from RNA polymerase II promoter	Biological process	-
CASQ2	845	calsequestrin 2 (cardiac muscle)	calcium-dependent protein binding	Molecular function	15485681
NGFR	4804	nerve growth factor receptor	negative regulation of fibroblast growth factor receptor signaling pathway	Biological process	-
SAR1B	51128	secretion associated, Ras related GTPase 1B	Golgi cisterna membrane	Cellular component	-
EPHX4	253152	epoxide hydrolase 4	hydrolase activity	Molecular function	-
CLDN15	24146	claudin 15	bicellular tight junction assembly	Biological process	-
TCF21	6943	transcription factor 21	E-box binding	Molecular function	-
PRG3	10394	proteoglycan 3	extracellular region	Cellular component	-
ST3GAL1	6482	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	N-acetylneuraminate metabolic process	Biological process	-
TGFBR1	7046	transforming growth factor, beta receptor 1	cell motility	Biological process	18625725
CBS	875	cystathionine-beta-synthase	nitrite reductase (NO-forming) activity	Molecular function	24416422
ERGIC1	57222	endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1	Golgi membrane	Cellular component	-
MEF2A	4205	myocyte enhancer factor 2A	protein binding	Molecular function	16043483
KIDINS220	57498	kinase D-interacting substrate, 220kDa	late endosome	Cellular component	-
CAPN5	726	calpain 5	extracellular exosome	Cellular component	19056867
EXOSC10	5394	exosome component 10	dosage compensation by inactivation of X chromosome	Biological process	-
RAB29	8934	RAB29, member RAS oncogene family	Rab protein signal transduction	Biological process	-
SLC51A	200931	solute carrier family 51, alpha subunit	endoplasmic reticulum membrane	Cellular component	-
PYCARD	29108	PYD and CARD domain containing	cellular response to tumor necrosis factor	Biological process	12486103
NFATC1	4772	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	protein binding	Molecular function	14979875
MAGI2	9863	membrane associated guanylate kinase, WW and PDZ domain containing 2	protein complex	Cellular component	-
PDGFB	5155	platelet-derived growth factor beta polypeptide	positive regulation of glomerular mesangial cell proliferation	Biological process	11788434
TMED10	10972	transmembrane emp24-like trafficking protein 10 (yeast)	vesicle targeting, to, from or within Golgi	Biological process	-
TRIM21	6737	tripartite motif containing 21	RNA binding	Molecular function	-
SDK2	54549	sidekick cell adhesion molecule 2	cell adhesion	Biological process	-
ACACA	31	acetyl-CoA carboxylase alpha	metal ion binding	Molecular function	-
RC3H1	149041	ring finger and CCCH-type domains 1	protein ubiquitination	Biological process	19217324
CHP1	11261	calcineurin-like EF-hand protein 1	cytoplasmic microtubule organization	Biological process	-
SDCCAG8	10806	serologically defined colon cancer antigen 8	protein binding	Molecular function	20835237
PKD2	5311	polycystic kidney disease 2 (autosomal dominant)	phosphoprotein binding	Molecular function	19801576
CAPNS1	826	calpain, small subunit 1	calcium ion binding	Molecular function	-
AQP2	359	aquaporin 2 (collecting duct)	response to lipopolysaccharide	Biological process	-
ZNF667	63934	zinc finger protein 667	nucleus	Cellular component	-
CST5	1473	cystatin D	cysteine-type endopeptidase inhibitor activity	Molecular function	8083219
RAC2	5880	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	GTPase activity	Molecular function	-
SUPT5H	6829	suppressor of Ty 5 homolog (S. cerevisiae)	viral process	Biological process	-
HDAC10	83933	histone deacetylase 10	histone deacetylation	Biological process	11739383
DLGAP5	9787	discs, large (Drosophila) homolog-associated protein 5	dephosphorylation	Biological process	-
PIP5K1A	8394	phosphatidylinositol-4-phosphate 5-kinase, type I, alpha	actin cytoskeleton reorganization	Biological process	20660631
POLM	27434	polymerase (DNA directed), mu	DNA repair	Biological process	-
CMAHP	8418	cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene	cytoskeleton	Cellular component	19890979
PDX1	3651	pancreatic and duodenal homeobox 1	response to leucine	Biological process	-
PROSC	11212	proline synthetase co-transcribed homolog (bacterial)	cytoplasm	Cellular component	10496079
HCFC1	3054	host cell factor C1	identical protein binding	Molecular function	12670868
SUPT5H	6829	suppressor of Ty 5 homolog (S. cerevisiae)	cell cycle	Biological process	10075709
TERT	7015	telomerase reverse transcriptase	protein binding	Molecular function	12699629
LY75	4065	lymphocyte antigen 75	receptor activity	Molecular function	9553150
NR1D1	9572	nuclear receptor subfamily 1, group D, member 1	cell differentiation	Biological process	-
MMP2	4313	matrix metallopeptidase 2	proteolysis	Biological process	15863497
BAG1	573	BCL2-associated athanogene	nucleus	Cellular component	-
ZNF574	64763	zinc finger protein 574	DNA binding	Molecular function	-
PHF1	5252	PHD finger protein 1	cellular response to DNA damage stimulus	Biological process	23142980
JUN	3725	jun proto-oncogene	regulation of cell proliferation	Biological process	-
CPT2	1376	carnitine palmitoyltransferase 2	nucleoplasm	Cellular component	-
KNG1	3827	kininogen 1	extracellular space	Cellular component	16502470
SFXN2	118980	sideroflexin 2	iron ion homeostasis	Biological process	-
PTPN5	84867	protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)	endoplasmic reticulum membrane	Cellular component	-
C6	729	complement component 6	protein binding	Molecular function	17474147
KRT75	9119	keratin 75, type II	structural molecule activity	Molecular function	-
ISOC1	51015	isochorismatase domain containing 1	peroxisome	Cellular component	14561759
APP	351	amyloid beta (A4) precursor protein	neuron apoptotic process	Biological process	19225519
CYP19A1	1588	cytochrome P450, family 19, subfamily A, polypeptide 1	prostate gland growth	Biological process	-
SFTPC	6440	surfactant protein C	respiratory gaseous exchange	Biological process	-
TAF11	6882	TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa	regulation of transcription, DNA-templated	Biological process	-
CITED1	4435	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1	cytosol	Cellular component	16864582
MTPAP	55149	mitochondrial poly(A) polymerase	polynucleotide adenylyltransferase activity	Molecular function	21292163
CCR8	1237	chemokine (C-C motif) receptor 8	C-C chemokine receptor activity	Molecular function	-
HIST3H2BB	128312	histone cluster 3, H2bb	nucleosome assembly	Biological process	-
EDN2	1907	endothelin 2	positive regulation of the force of heart contraction by chemical signal	Biological process	1652300
ALPI	248	alkaline phosphatase, intestinal	magnesium ion binding	Molecular function	-
RAP2B	5912	RAP2B, member of RAS oncogene family	platelet aggregation	Biological process	18582561
LCT	3938	lactase	glycosylceramidase activity	Molecular function	-
CATSPER1	117144	cation channel, sperm associated 1	regulation of ion transmembrane transport	Biological process	-
HRG	3273	histidine-rich glycoprotein	extracellular exosome	Cellular component	19056867
RFX6	222546	regulatory factor X, 6	type B pancreatic cell differentiation	Biological process	-
ADGRA2	25960	adhesion G protein-coupled receptor A2	regulation of angiogenesis	Biological process	-
SLC6A15	55117	solute carrier family 6 (neutral amino acid transporter), member 15	transmembrane transport	Biological process	-
MYADM	91663	myeloid-associated differentiation marker	extracellular exosome	Cellular component	23376485
EXOSC5	56915	exosome component 5	exosome (RNase complex)	Cellular component	20531389
IL25	64806	interleukin 25	inflammatory response to antigenic stimulus	Biological process	-
SLC26A3	1811	solute carrier family 26 (anion exchanger), member 3	sequence-specific DNA binding transcription factor activity	Molecular function	7683425
C17orf70	80233	chromosome 17 open reading frame 70	DNA binding	Molecular function	-
APBB1	322	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	nuclear speck	Cellular component	-
ARRB2	409	arrestin, beta 2	negative regulation of protein ubiquitination	Biological process	16378096
ITPKC	80271	inositol-trisphosphate 3-kinase C	cytosol	Cellular component	-
KIT	3815	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	phosphatidylinositol-mediated signaling	Biological process	-
ATRX	546	alpha thalassemia/mental retardation syndrome X-linked	chromatin remodeling	Biological process	20651253
HMGCL	3155	3-hydroxymethyl-3-methylglutaryl-CoA lyase	mitochondrial matrix	Cellular component	-
BDKRB2	624	bradykinin receptor B2	integral component of plasma membrane	Cellular component	7916737
ANAPC7	51434	anaphase promoting complex subunit 7	cell division	Biological process	-
BIRC3	330	baculoviral IAP repeat containing 3	regulation of innate immune response	Biological process	21447281
CTNNA3	29119	catenin (cadherin-associated protein), alpha 3	regulation of ventricular cardiac muscle cell action potential	Biological process	23136403
ATF2	1386	activating transcription factor 2	toll-like receptor 5 signaling pathway	Biological process	-
DPPA2	151871	developmental pluripotency associated 2	regulation of histone methylation	Biological process	-
SYT10	341359	synaptotagmin X	calcium ion binding	Molecular function	-
SULF2	55959	sulfatase 2	arylsulfatase activity	Molecular function	19520866
RREB1	6239	ras responsive element binding protein 1	nuclear speck	Cellular component	-
MLXIPL	51085	MLX interacting protein-like	regulation of fatty acid biosynthetic process	Biological process	-
PDE4D	5144	phosphodiesterase 4D, cAMP-specific	aging	Biological process	-
ZNF80	7634	zinc finger protein 80	DNA binding	Molecular function	-
TBP	6908	TATA box binding protein	transcription from RNA polymerase I promoter	Biological process	-
PLCH2	9651	phospholipase C, eta 2	inositol phosphate metabolic process	Biological process	-
MYBPC2	4606	myosin binding protein C, fast type	protein binding	Molecular function	23414517
CTR9	9646	CTR9, Paf1/RNA polymerase II complex component	transcriptionally active chromatin	Cellular component	-
OR4D6	219983	olfactory receptor, family 4, subfamily D, member 6	G-protein coupled receptor activity	Molecular function	-
PLA2G12B	84647	phospholipase A2, group XIIB	cholesterol homeostasis	Biological process	-
NT5C	30833	5', 3'-nucleotidase, cytosolic	extracellular exosome	Cellular component	19056867
DDN	23109	dendrin	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
NFATC4	4776	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	cytoplasm	Cellular component	-
PXN	5829	paxillin	microtubule associated complex	Cellular component	10840040
ACSF3	197322	acyl-CoA synthetase family member 3	acid-thiol ligase activity	Molecular function	17762044
HADHB	3032	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit	long-chain-3-hydroxyacyl-CoA dehydrogenase activity	Molecular function	-
DAGLB	221955	diacylglycerol lipase, beta	blood coagulation	Biological process	-
PPIC	5480	peptidylprolyl isomerase C (cyclophilin C)	peptidyl-prolyl cis-trans isomerase activity	Molecular function	-
PELI1	57162	pellino E3 ubiquitin protein ligase 1	negative regulation of T cell proliferation	Biological process	-
RRP8	23378	ribosomal RNA processing 8, methyltransferase, homolog (yeast)	methylation	Biological process	-
VPS4A	27183	vacuolar protein sorting 4 homolog A (S. cerevisiae)	positive regulation of viral release from host cell	Biological process	11595185
EP400	57634	E1A binding protein p400	histone H4 acetylation	Biological process	14966270
SLC25A23	79085	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23	integral component of membrane	Cellular component	-
NR6A1	2649	nuclear receptor subfamily 6, group A, member 1	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
CLIC4	25932	chloride intracellular channel 4	cell-cell junction	Cellular component	14569596
SLC9A3R1	9368	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1	cytoplasm	Cellular component	17895247
MCRS1	10445	microspherule protein 1	MLL1 complex	Cellular component	15960975
ITIH2	3698	inter-alpha-trypsin inhibitor heavy chain 2	extracellular exosome	Cellular component	20458337
KRT14	3861	keratin 14, type I	keratin filament	Cellular component	7679677
RAB35	11021	RAB35, member RAS oncogene family	Golgi membrane	Cellular component	-
AXIN2	8313	axin 2	positive regulation of epithelial to mesenchymal transition	Biological process	17072303
SNRPF	6636	small nuclear ribonucleoprotein polypeptide F	methylosome	Cellular component	18984161
CAPZB	832	capping protein (actin filament) muscle Z-line, beta	extracellular exosome	Cellular component	19056867
EIF3B	8662	eukaryotic translation initiation factor 3, subunit B	eukaryotic 43S preinitiation complex	Cellular component	-
CBFA2T3	863	core-binding factor, runt domain, alpha subunit 2; translocated to, 3	transcription, DNA-templated	Biological process	-
RBM22	55696	RNA binding motif protein 22	protein binding	Molecular function	25416956
BAX	581	BCL2-associated X protein	protein homodimerization activity	Molecular function	9111042
CAV1	857	caveolin 1, caveolae protein, 22kDa	regulation of cell communication by electrical coupling involved in cardiac conduction	Biological process	-
CYP1A2	1544	cytochrome P450, family 1, subfamily A, polypeptide 2	response to lipopolysaccharide	Biological process	-
SUV39H2	79723	suppressor of variegation 3-9 homolog 2 (Drosophila)	chromatin remodeling	Biological process	10949293
TESC	54997	tescalcin	positive regulation of granulocyte differentiation	Biological process	20060826
ATP1A2	477	ATPase, Na+/K+ transporting, alpha 2 polypeptide	metal ion binding	Molecular function	-
SLITRK6	84189	SLIT and NTRK-like family, member 6	vestibulocochlear nerve development	Biological process	-
ADM	133	adrenomedullin	androgen metabolic process	Biological process	-
F2R	2149	coagulation factor II (thrombin) receptor	early endosome	Cellular component	22547407
AP2B1	163	adaptor-related protein complex 2, beta 1 subunit	epidermal growth factor receptor signaling pathway	Biological process	-
NLGN1	22871	neuroligin 1	postsynaptic density protein 95 clustering	Biological process	-
UBA52	7311	ubiquitin A-52 residue ribosomal protein fusion product 1	viral transcription	Biological process	-
FRS3	10817	fibroblast growth factor receptor substrate 3	signal transduction	Biological process	8761293
GLRA1	2741	glycine receptor, alpha 1	protein binding	Molecular function	11929858
FOXP1	27086	forkhead box P1	regulation of monocyte differentiation	Biological process	15286807
RELB	5971	v-rel avian reticuloendotheliosis viral oncogene homolog B	RNA polymerase II regulatory region sequence-specific DNA binding	Molecular function	-
SUMO1	7341	small ubiquitin-like modifier 1	negative regulation of delayed rectifier potassium channel activity	Biological process	19223394
EPB41L5	57669	erythrocyte membrane protein band 4.1 like 5	actomyosin structure organization	Biological process	-
ADGRL1	22859	adhesion G protein-coupled receptor L1	plasma membrane	Cellular component	-
ISL1	3670	ISL LIM homeobox 1	chromatin binding	Molecular function	-
CEP290	80184	centrosomal protein 290kDa	microtubule minus-end binding	Molecular function	16682973
MBD3L3	653657	methyl-CpG binding domain protein 3-like 3	transcription, DNA-templated	Biological process	-
PFKFB3	5209	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	brain development	Biological process	-
BTBD11	121551	BTB (POZ) domain containing 11	SMAD protein signal transduction	Biological process	-
GTF2H4	2968	general transcription factor IIH, polypeptide 4, 52kDa	protein kinase activity	Molecular function	9852112
TXNDC8	255220	thioredoxin domain containing 8 (spermatozoa)	extracellular exosome	Cellular component	19056867
SART1	9092	squamous cell carcinoma antigen recognized by T cells	protein binding	Molecular function	15620657
CLASP2	23122	cytoplasmic linker associated protein 2	microtubule plus-end binding	Molecular function	11290329
GSX2	170825	GS homeobox 2	olfactory bulb interneuron differentiation	Biological process	-
ANXA6	309	annexin A6	regulation of muscle contraction	Biological process	-
MAPK1	5594	mitogen-activated protein kinase 1	cytoplasm	Cellular component	-
ITPR3	3710	inositol 1,4,5-trisphosphate receptor, type 3	Fc-gamma receptor signaling pathway involved in phagocytosis	Biological process	-
NGB	58157	neuroglobin	mitochondrion	Cellular component	-
POMC	5443	proopiomelanocortin	cytoplasm	Cellular component	-
GRIN2B	2904	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	suckling behavior	Biological process	-
TSHZ1	10194	teashirt zinc finger homeobox 1	nucleus	Cellular component	-
TLX1	3195	T-cell leukemia homeobox 1	neuron differentiation	Biological process	-
SFRP1	6422	secreted frizzled-related protein 1	negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation	Biological process	17994217
USP17L19	100287404	ubiquitin specific peptidase 17-like family member 19	regulation of proteasomal protein catabolic process	Biological process	-
TWF2	11344	twinfilin actin-binding protein 2	sequestering of actin monomers	Biological process	18837697
MAEL	84944	maelstrom spermatogenic transposon silencer	XY body	Cellular component	-
MARK4	57787	MAP/microtubule affinity-regulating kinase 4	microtubule cytoskeleton organization	Biological process	14594945
HIST1H1E	3008	histone cluster 1, H1e	nucleus	Cellular component	17540172
SHH	6469	sonic hedgehog	patterning of blood vessels	Biological process	-
AP4M1	9179	adaptor-related protein complex 4, mu 1 subunit	protein binding	Molecular function	25416956
NOX1	27035	NADPH oxidase 1	cellular response to hyperoxia	Biological process	-
HYKK	123688	hydroxylysine kinase	hydroxylysine kinase activity	Molecular function	-
TRIP11	9321	thyroid hormone receptor interactor 11	outer acrosomal membrane	Cellular component	-
LRP4	4038	low density lipoprotein receptor-related protein 4	integral component of membrane	Cellular component	-
TNRC6C	57690	trinucleotide repeat containing 6C	cytosol	Cellular component	-
TRIM38	10475	tripartite motif containing 38	positive regulation of viral genome replication	Biological process	-
PHACTR1	221692	phosphatase and actin regulator 1	nucleus	Cellular component	-
SNCA	6622	synuclein, alpha (non A4 component of amyloid precursor)	mitochondrial respiratory chain complex I	Cellular component	24252804
NUP98	4928	nucleoporin 98kDa	nuclear pore organization	Biological process	9348540
LCN2	3934	lipocalin 2	extracellular space	Cellular component	16502470
CASC5	57082	cancer susceptibility candidate 5	CENP-A containing nucleosome assembly	Biological process	-
FLT4	2324	fms-related tyrosine kinase 4	positive regulation of cell proliferation	Biological process	19779139
UPF3A	65110	UPF3 regulator of nonsense transcripts homolog A (yeast)	intracellular membrane-bounded organelle	Cellular component	-
CXCR4	7852	chemokine (C-X-C motif) receptor 4	activation of MAPK activity	Biological process	10570282
ENPP1	5167	ectonucleotide pyrophosphatase/phosphodiesterase 1	plasma membrane	Cellular component	-
ADCYAP1R1	117	adenylate cyclase activating polypeptide 1 (pituitary) receptor type I	integral component of plasma membrane	Cellular component	7902709
UBC	7316	ubiquitin C	transforming growth factor beta receptor signaling pathway	Biological process	-
IL36A	27179	interleukin 36, alpha	positive regulation of interleukin-6 production	Biological process	-
NPY1R	4886	neuropeptide Y receptor Y1	integral component of plasma membrane	Cellular component	1317848
MRPS9	64965	mitochondrial ribosomal protein S9	DNA damage response, detection of DNA damage	Biological process	15300802
PUS3	83480	pseudouridylate synthase 3	tRNA pseudouridine synthesis	Biological process	-
CRX	1406	cone-rod homeobox	regulation of transcription, DNA-templated	Biological process	-
MAP2K7	5609	mitogen-activated protein kinase kinase 7	protein binding	Molecular function	15299019
HLA-DRB1	3123	major histocompatibility complex, class II, DR beta 1	ER to Golgi transport vesicle membrane	Cellular component	-
NFKBIA	4792	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	positive regulation of cholesterol efflux	Biological process	16938301
PIK3R5	23533	phosphoinositide-3-kinase, regulatory subunit 5	phospholipid metabolic process	Biological process	-
MC3R	4159	melanocortin 3 receptor	regulation of blood pressure	Biological process	-
GGTLC1	92086	gamma-glutamyltransferase light chain 1	leukotriene biosynthetic process	Biological process	-
RCC2	55920	regulator of chromosome condensation 2	cytosol	Cellular component	-
TXN	7295	thioredoxin	mitochondrion	Cellular component	-
SLC7A5	8140	solute carrier family 7 (amino acid transporter light chain, L system), member 5	cytoplasm	Cellular component	-
POM121	9883	POM121 transmembrane nucleoporin	regulation of cellular response to heat	Biological process	-
FBXL2	25827	F-box and leucine-rich repeat protein 2	regulation of phosphatidylinositol 3-kinase signaling	Biological process	23604317
LAMTOR4	389541	late endosomal/lysosomal adaptor, MAPK and MTOR activator 4	guanyl-nucleotide exchange factor activity	Molecular function	22980980
ABCB4	5244	ATP-binding cassette, sub-family B (MDR/TAP), member 4	xenobiotic-transporting ATPase activity	Molecular function	-
NXPH3	11248	neurexophilin 3	neuropeptide signaling pathway	Biological process	9570794
SNRPD3	6634	small nuclear ribonucleoprotein D3 polypeptide 18kDa	transcription from RNA polymerase II promoter	Biological process	-
RAB3D	9545	RAB3D, member RAS oncogene family	peptidyl-cysteine methylation	Biological process	-
OR52K1	390036	olfactory receptor, family 52, subfamily K, member 1	plasma membrane	Cellular component	-
MUC1	4582	mucin 1, cell surface associated	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	Biological process	15710329
ADCY2	108	adenylate cyclase 2 (brain)	transmembrane transport	Biological process	-
NLRP10	338322	NLR family, pyrin domain containing 10	innate immune response	Biological process	-
LMAN2	10960	lectin, mannose-binding 2	glycoprotein binding	Molecular function	20477988
FGF16	8823	fibroblast growth factor 16	regulation of sprouting angiogenesis	Biological process	16756958
PTRHD1	391356	peptidyl-tRNA hydrolase domain containing 1	metabolic process	Biological process	-
RPL4	6124	ribosomal protein L4	cytosol	Cellular component	-
PROS1	5627	protein S (alpha)	fibrinolysis	Biological process	-
PTRH2	51651	peptidyl-tRNA hydrolase 2	metabolic process	Biological process	-
HOXC4	3221	homeobox C4	nucleus	Cellular component	-
NPC1	4864	Niemann-Pick disease, type C1	cholesterol metabolic process	Biological process	-
HIF1A	3091	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	negative regulation of TOR signaling	Biological process	-
ITPR3	3710	inositol 1,4,5-trisphosphate receptor, type 3	receptor complex	Cellular component	23382219
PCDHA4	56144	protocadherin alpha 4	nervous system development	Biological process	10380929
TMF1	7110	TATA element modulatory factor 1	protein binding	Molecular function	20195357
CSNK2A1	1457	casein kinase 2, alpha 1 polypeptide	mitotic cell cycle	Biological process	-
PTEN	5728	phosphatase and tensin homolog	protein binding	Molecular function	15951562
SIAH1	6477	siah E3 ubiquitin protein ligase 1	nucleus	Cellular component	-
GDF15	9518	growth differentiation factor 15	cytokine activity	Molecular function	-
CYBA	1535	cytochrome b-245, alpha polypeptide	Golgi apparatus	Cellular component	-
IFNAR2	3455	interferon (alpha, beta and omega) receptor 2	cell proliferation	Biological process	-
UNC93A	54346	unc-93 homolog A (C. elegans)	integral component of membrane	Cellular component	12381271
WNT3	7473	wingless-type MMTV integration site family, member 3	limb bud formation	Biological process	14872406
RPL3L	6123	ribosomal protein L3-like	membrane	Cellular component	19946888
OXCT1	5019	3-oxoacid CoA transferase 1	response to activity	Biological process	-
CMPK1	51727	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic	nucleus	Cellular component	-
CREG1	8804	cellular repressor of E1A-stimulated genes 1	transcription factor binding	Molecular function	-
APBB1	322	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	cell cycle arrest	Biological process	-
CD47	961	CD47 molecule	protein binding	Molecular function	15383453
TGFB1	7040	transforming growth factor, beta 1	endoderm development	Biological process	-
CYBA	1535	cytochrome b-245, alpha polypeptide	metal ion binding	Molecular function	-
PRMT2	3275	protein arginine methyltransferase 2	protein-arginine N-methyltransferase activity	Molecular function	-
PVRL2	5819	poliovirus receptor-related 2 (herpesvirus entry mediator B)	integral component of membrane	Cellular component	12913096
KLHL3	26249	kelch-like family member 3	cytosol	Cellular component	22406640
MRPS7	51081	mitochondrial ribosomal protein S7	mitochondrial translational elongation	Biological process	-
HIST1H3C	8352	histone cluster 1, H3c	nuclear nucleosome	Cellular component	20498094
GPC2	221914	glypican 2	lysosomal lumen	Cellular component	-
YIF1A	10897	Yip1 interacting factor homolog A (S. cerevisiae)	endoplasmic reticulum unfolded protein response	Biological process	-
GHRHR	2692	growth hormone releasing hormone receptor	positive regulation of multicellular organism growth	Biological process	8528260
CCL5	6352	chemokine (C-C motif) ligand 5	positive regulation of epithelial cell proliferation	Biological process	-
CXADR	1525	coxsackie virus and adenovirus receptor	growth cone	Cellular component	-
NUCB2	4925	nucleobindin 2	endoplasmic reticulum-Golgi intermediate compartment	Cellular component	15308636
PGM2L1	283209	phosphoglucomutase 2-like 1	glucose metabolic process	Biological process	-
MAPK7	5598	mitogen-activated protein kinase 7	nucleoplasm	Cellular component	-
TMEM184A	202915	transmembrane protein 184A	regulation of secretion	Biological process	-
CYB5A	1528	cytochrome b5 type A (microsomal)	heme binding	Molecular function	-
TLX3	30012	T-cell leukemia homeobox 3	regulation of transcription, DNA-templated	Biological process	-
AP4E1	23431	adaptor-related protein complex 4, epsilon 1 subunit	membrane organization	Biological process	-
HSD17B8	7923	hydroxysteroid (17-beta) dehydrogenase 8	protein binding	Molecular function	19571038
MUC6	4588	mucin 6, oligomeric mucus/gel-forming	cellular protein metabolic process	Biological process	-
HK1	3098	hexokinase 1	carbohydrate metabolic process	Biological process	-
NSFL1C	55968	NSFL1 (p97) cofactor (p47)	autophagosome assembly	Biological process	-
HIST1H3J	8356	histone cluster 1, H3j	negative regulation of gene expression, epigenetic	Biological process	-
ACE2	59272	angiotensin I converting enzyme 2	peptide hormone binding	Molecular function	-
PRNP	5621	prion protein	negative regulation of interleukin-2 production	Biological process	-
IFNGR1	3459	interferon gamma receptor 1	plasma membrane	Cellular component	-
TFDP1	7027	transcription factor Dp-1	intrinsic apoptotic signaling pathway	Biological process	-
WNT10B	7480	wingless-type MMTV integration site family, member 10B	smoothened signaling pathway	Biological process	-
GTF2E1	2960	general transcription factor IIE, polypeptide 1, alpha 56kDa	nucleoplasm	Cellular component	-
PRIMPOL	201973	primase and polymerase (DNA-directed)	translesion synthesis	Biological process	24240614
BRPF1	7862	bromodomain and PHD finger containing, 1	MOZ/MORF histone acetyltransferase complex	Cellular component	16387653
FOXP2	93986	forkhead box P2	protein heterodimerization activity	Molecular function	-
DXO	1797	decapping exoribonuclease	nucleic acid phosphodiester bond hydrolysis	Biological process	-
DNAJB1	3337	DnaJ (Hsp40) homolog, subfamily B, member 1	nucleus	Cellular component	-
SH3BP4	23677	SH3-domain binding protein 4	endocytosis	Biological process	-
CTSE	1510	cathepsin E	protein autoprocessing	Biological process	-
ACER2	340485	alkaline ceramidase 2	small molecule metabolic process	Biological process	-
DEFB136	613210	defensin, beta 136	extracellular region	Cellular component	-
PSMC5	5705	proteasome (prosome, macropain) 26S subunit, ATPase, 5	G1/S transition of mitotic cell cycle	Biological process	-
RCL1	10171	RNA terminal phosphate cyclase-like 1	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Biological process	-
MMS22L	253714	MMS22-like, DNA repair protein	replication fork processing	Biological process	21055983
H2AFX	3014	H2A histone family, member X	DNA damage checkpoint	Biological process	17974976
CDKN1C	1028	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	nucleus	Cellular component	16943770
ATP1A3	478	ATPase, Na+/K+ transporting, alpha 3 polypeptide	potassium ion import	Biological process	10636900
INPPL1	3636	inositol polyphosphate phosphatase-like 1	endocytosis	Biological process	15668240
SMURF1	57154	SMAD specific E3 ubiquitin protein ligase 1	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	10458166
SCIN	85477	scinderin	phosphatidylinositol-4,5-bisphosphate binding	Molecular function	-
TSC1	7248	tuberous sclerosis 1	cell-matrix adhesion	Biological process	10806479
RPS27A	6233	ribosomal protein S27a	G2/M transition of mitotic cell cycle	Biological process	-
P2RY12	64805	purinergic receptor P2Y, G-protein coupled, 12	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway	Biological process	12578987
TMEM198	130612	transmembrane protein 198	integral component of membrane	Cellular component	-
NOX1	27035	NADPH oxidase 1	Rac GTPase binding	Molecular function	16636067
MT3	4504	metallothionein 3	negative regulation of transcription, DNA-templated	Biological process	-
GALR2	8811	galanin receptor 2	synaptic transmission	Biological process	9832121
CRHR1	1394	corticotropin releasing hormone receptor 1	protein complex binding	Molecular function	-
PRKAG1	5571	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	regulation of glycolytic process	Biological process	8663446
LATS2	26524	large tumor suppressor kinase 2	nucleus	Cellular component	10673337
PRMT7	54496	protein arginine methyltransferase 7	cell differentiation	Biological process	-
PRKRA	8575	protein kinase, interferon-inducible double stranded RNA dependent activator	pre-miRNA processing	Biological process	16424907
JAKMIP1	152789	janus kinase and microtubule interacting protein 1	cognition	Biological process	17519220
BMP2	650	bone morphogenetic protein 2	bone mineralization	Biological process	-
TERF2	7014	telomeric repeat binding factor 2	nuclear chromosome, telomeric region	Cellular component	-
ZNF107	51427	zinc finger protein 107	cellular_component	Cellular component	-
PXDN	7837	peroxidasin	oxidation-reduction process	Biological process	18929642
TREM2	54209	triggering receptor expressed on myeloid cells 2	positive regulation of antigen processing and presentation of peptide antigen via MHC class II	Biological process	11602640
JUP	3728	junction plakoglobin	focal adhesion	Cellular component	21423176
TUBB	203068	tubulin, beta class I	metabolic process	Biological process	-
RBM44	375316	RNA binding motif protein 44	intercellular bridge	Cellular component	-
SFTPA2	729238	surfactant protein A2	extracellular space	Cellular component	-
IL16	3603	interleukin 16	cytoplasm	Cellular component	-
RAB7B	338382	RAB7B, member RAS oncogene family	positive regulation of megakaryocyte differentiation	Biological process	20953574
IL21	59067	interleukin 21	positive regulation of T cell proliferation	Biological process	15207081
HAPLN1	1404	hyaluronan and proteoglycan link protein 1	skeletal system development	Biological process	-
PTK2B	2185	protein tyrosine kinase 2 beta	positive regulation of translation	Biological process	-
SNAI1	6615	snail family zinc finger 1	left/right pattern formation	Biological process	-
SMOX	54498	spermine oxidase	polyamine metabolic process	Biological process	-
OLIG3	167826	oligodendrocyte transcription factor 3	spinal cord motor neuron cell fate specification	Biological process	-
CA13	377677	carbonic anhydrase XIII	small molecule metabolic process	Biological process	-
TIRAP	114609	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	positive regulation of protein homodimerization activity	Biological process	12062447
HACD3	51495	3-hydroxyacyl-CoA dehydratase 3	positive regulation of GTPase activity	Biological process	10747961
POLR2I	5438	polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa	viral process	Biological process	-
SPATS2L	26010	spermatogenesis associated, serine-rich 2-like	cytoplasm	Cellular component	-
SRSF1	6426	serine/arginine-rich splicing factor 1	gene expression	Biological process	-
KLF12	11278	Kruppel-like factor 12	nucleus	Cellular component	-
NR1I3	9970	nuclear receptor subfamily 1, group I, member 3	signal transduction	Biological process	8020947
FITM2	128486	fat storage-inducing transmembrane protein 2	cellular triglyceride homeostasis	Biological process	18160536
KMT2A	4297	lysine (K)-specific methyltransferase 2A	MLL1 complex	Cellular component	15960975
SFRP1	6422	secreted frizzled-related protein 1	ureteric bud development	Biological process	-
S100A6	6277	S100 calcium binding protein A6	extrinsic component of cytoplasmic side of plasma membrane	Cellular component	19724273
RPL11	6135	ribosomal protein L11	rRNA binding	Molecular function	-
IGF2BP2	10644	insulin-like growth factor 2 mRNA binding protein 2	anatomical structure morphogenesis	Biological process	9891060
ZNF503	84858	zinc finger protein 503	nucleic acid binding	Molecular function	-
TWIST2	117581	twist family bHLH transcription factor 2	negative regulation of transcription, DNA-templated	Biological process	-
ODF2L	57489	outer dense fiber of sperm tails 2-like	centrosome	Cellular component	21399614
SYCP1	6847	synaptonemal complex protein 1	transverse filament	Cellular component	-
LCMT2	9836	leucine carboxyl methyltransferase 2	methyltransferase activity	Molecular function	-
ENAH	55740	enabled homolog (Drosophila)	intracellular transport	Biological process	-
PFKM	5213	phosphofructokinase, muscle	canonical glycolysis	Biological process	-
MRPS36	92259	mitochondrial ribosomal protein S36	structural constituent of ribosome	Molecular function	11279123
APCS	325	amyloid P component, serum	virion binding	Molecular function	23544079
FKBP4	2288	FK506 binding protein 4, 59kDa	protein binding, bridging	Molecular function	2378870
CNOT6	57472	CCR4-NOT transcription complex, subunit 6	transcription, DNA-templated	Biological process	-
TRIM51FP	283257	tripartite motif-containing 51F, pseudogene	intracellular	Cellular component	-
TBC1D10B	26000	TBC1 domain family, member 10B	cytoplasm	Cellular component	-
HMGA1	3159	high mobility group AT-hook 1	response to virus	Biological process	17005673
CEP192	55125	centrosomal protein 192kDa	phosphatase binding	Molecular function	19389623
KLF1	10661	Kruppel-like factor 1 (erythroid)	sequence-specific DNA binding transcription factor activity	Molecular function	8924208
SLC17A4	10050	solute carrier family 17, member 4	phosphate-containing compound metabolic process	Biological process	10319585
DST	667	dystonin	integral component of membrane	Cellular component	-
RHAG	6005	Rh-associated glycoprotein	small molecule metabolic process	Biological process	-
DBH	1621	dopamine beta-hydroxylase (dopamine beta-monooxygenase)	copper ion binding	Molecular function	-
ZNF780B	163131	zinc finger protein 780B	metal ion binding	Molecular function	-
IMP3	55272	IMP3, U3 small nucleolar ribonucleoprotein	small-subunit processome	Cellular component	-
DPY30	84661	dpy-30 homolog (C. elegans)	chromatin organization	Biological process	-
ADGRF1	266977	adhesion G protein-coupled receptor F1	plasma membrane	Cellular component	-
LOC149950	149950	uncharacterized LOC149950	protein binding	Molecular function	25416956
NKX2-5	1482	NK2 homeobox 5	transcription factor complex	Cellular component	9312027
SKIL	6498	SKI-like proto-oncogene	transforming growth factor beta receptor signaling pathway	Biological process	-
MC3R	4159	melanocortin 3 receptor	homoiothermy	Biological process	-
CNBD2	140894	cyclic nucleotide binding domain containing 2	spermatogenesis	Biological process	-
KHK	3795	ketohexokinase (fructokinase)	protein binding	Molecular function	25416956
COL19A1	1310	collagen, type XIX, alpha 1	proteinaceous extracellular matrix	Cellular component	1639419
CRKL	1399	v-crk avian sarcoma virus CT10 oncogene homolog-like	poly(A) RNA binding	Molecular function	22658674
CERS4	79603	ceramide synthase 4	sphingosine N-acyltransferase activity	Molecular function	-
ITGA4	3676	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	cell surface	Cellular component	1715889
UBB	7314	ubiquitin B	fat pad development	Biological process	-
VTN	7448	vitronectin	scavenger receptor activity	Molecular function	-
TAF9	6880	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa	response to interleukin-1	Biological process	15489227
UBB	7314	ubiquitin B	endosomal transport	Biological process	-
MYBPC3	4607	myosin binding protein C, cardiac	positive regulation of ATPase activity	Biological process	-
C5	727	complement component 5	cell chemotaxis	Biological process	10820279
KRI1	65095	KRI1 homolog (S. cerevisiae)	nucleolus	Cellular component	-
EDC3	80153	enhancer of mRNA decapping 3	cytosol	Cellular component	-
CTSD	1509	cathepsin D	melanosome	Cellular component	-
KRT25	147183	keratin 25, type I	cytoplasm	Cellular component	-
EZH2	2146	enhancer of zeste 2 polycomb repressive complex 2 subunit	DNA methylation	Biological process	-
DDX6	1656	DEAD (Asp-Glu-Ala-Asp) box helicase 6	helicase activity	Molecular function	1394235
MRPL34	64981	mitochondrial ribosomal protein L34	mitochondrial translational elongation	Biological process	-
PCK1	5105	phosphoenolpyruvate carboxykinase 1 (soluble)	oxaloacetate metabolic process	Biological process	-
MKRN2	23609	makorin ring finger protein 2	ligase activity	Molecular function	-
SQLE	6713	squalene epoxidase	oxidation-reduction process	Biological process	-
ATP6V1A	523	ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A	ATP metabolic process	Biological process	-
NFE2L2	4780	nuclear factor, erythroid 2-like 2	chromatin	Cellular component	-
CYP2R1	120227	cytochrome P450, family 2, subfamily R, polypeptide 1	oxygen binding	Molecular function	-
IFNLR1	163702	interferon, lambda receptor 1	protein binding	Molecular function	12469119
FZD2	2535	frizzled class receptor 2	cochlea morphogenesis	Biological process	-
SF3B2	10992	splicing factor 3b, subunit 2, 145kDa	U12-type spliceosomal complex	Cellular component	15146077
BHLHE22	27319	basic helix-loop-helix family, member e22	anterior commissure morphogenesis	Biological process	-
RAP1GAP	5909	RAP1 GTPase activating protein	metabolic process	Biological process	10476970
DEFB132	400830	defensin, beta 132	cell surface	Cellular component	-
USP26	83844	ubiquitin specific peptidase 26	cysteine-type endopeptidase activity	Molecular function	-
SLC2A7	155184	solute carrier family 2 (facilitated glucose transporter), member 7	sugar:proton symporter activity	Molecular function	-
FRMPD4	9758	FERM and PDZ domain containing 4	positive regulation of synapse structural plasticity	Biological process	19118189
PLCZ1	89869	phospholipase C, zeta 1	perinuclear region of cytoplasm	Cellular component	-
NEURL1	9148	neuralized E3 ubiquitin protein ligase 1	regulation of translation	Biological process	-
C2CD2L	9854	C2CD2-like	positive regulation of insulin secretion involved in cellular response to glucose stimulus	Biological process	-
ATXN7	6314	ataxin 7	transcription, DNA-templated	Biological process	-
GLI3	2737	GLI family zinc finger 3	positive regulation of protein import into nucleus	Biological process	-
HGF	3082	hepatocyte growth factor (hepapoietin A; scatter factor)	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	Biological process	-
ACAD11	84129	acyl-CoA dehydrogenase family, member 11	long-chain-acyl-CoA dehydrogenase activity	Molecular function	21237683
IL17B	27190	interleukin 17B	extracellular space	Cellular component	-
ANK2	287	ankyrin 2, neuronal	regulation of protein stability	Biological process	18832177
MRPS30	10884	mitochondrial ribosomal protein S30	ribosome	Cellular component	-
HMGCL	3155	3-hydroxymethyl-3-methylglutaryl-CoA lyase	cellular lipid metabolic process	Biological process	-
PCSK6	5046	proprotein convertase subtilisin/kexin type 6	peptide hormone processing	Biological process	9242664
KLK12	43849	kallikrein-related peptidase 12	serine-type peptidase activity	Molecular function	15300858
ALDH6A1	4329	aldehyde dehydrogenase 6 family, member A1	thymine metabolic process	Biological process	-
NEURL1	9148	neuralized E3 ubiquitin protein ligase 1	translation factor activity, non-nucleic acid binding	Molecular function	-
MAP2K5	5607	mitogen-activated protein kinase kinase 5	ATP binding	Molecular function	-
COX7C	1350	cytochrome c oxidase subunit VIIc	gene expression	Biological process	-
NOTCH1	4851	notch 1	regulation of somitogenesis	Biological process	-
ERCC4	2072	excision repair cross-complementation group 4	cellular response to UV	Biological process	17055345
PTK2B	2185	protein tyrosine kinase 2 beta	regulation of macrophage chemotaxis	Biological process	-
DMAP1	55929	DNA methyltransferase 1 associated protein 1	DNA methylation	Biological process	10888872
APOA1BP	128240	apolipoprotein A-I binding protein	biological_process	Biological process	-
SHH	6469	sonic hedgehog	salivary gland cavitation	Biological process	-
DAO	1610	D-amino-acid oxidase	dopamine biosynthetic process	Biological process	17303072
AHCY	191	adenosylhomocysteinase	extracellular exosome	Cellular component	19056867
DPY19L1	23333	dpy-19-like 1 (C. elegans)	mannosyltransferase activity	Molecular function	-
HIST1H2BD	3017	histone cluster 1, H2bd	chromatin organization	Biological process	-
ADAM8	101	ADAM metallopeptidase domain 8	cell morphogenesis	Biological process	-
TET2	54790	tet methylcytosine dioxygenase 2	liver morphogenesis	Biological process	-
CDKN3	1033	cyclin-dependent kinase inhibitor 3	regulation of cyclin-dependent protein serine/threonine kinase activity	Biological process	8242750
ACACA	31	acetyl-CoA carboxylase alpha	positive regulation of cellular metabolic process	Biological process	-
B4GALT4	8702	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4	metal ion binding	Molecular function	-
SOX1	6656	SRY (sex determining region Y)-box 1	sequence-specific DNA binding transcription factor activity	Molecular function	9337405
OR10H5	284433	olfactory receptor, family 10, subfamily H, member 5	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
CYP2A13	1553	cytochrome P450, family 2, subfamily A, polypeptide 13	aromatase activity	Molecular function	-
SCP2	6342	sterol carrier protein 2	extracellular exosome	Cellular component	23376485
RAF1	5894	Raf-1 proto-oncogene, serine/threonine kinase	cell proliferation	Biological process	8063729
F11R	50848	F11 receptor	extracellular matrix organization	Biological process	-
KCNA1	3736	potassium channel, voltage gated shaker related subfamily A, member 1	protein homooligomerization	Biological process	-
STEAP2	261729	STEAP family member 2, metalloreductase	ferric-chelate reductase (NADPH) activity	Molecular function	-
MPO	4353	myeloperoxidase	respiratory burst involved in defense response	Biological process	-
DNAJA4	55466	DnaJ (Hsp40) homolog, subfamily A, member 4	chaperone binding	Molecular function	21231916
ITGA5	3678	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	leukocyte migration	Biological process	-
ZSCAN22	342945	zinc finger and SCAN domain containing 22	nucleus	Cellular component	-
ACADL	33	acyl-CoA dehydrogenase, long chain	small molecule metabolic process	Biological process	-
AP2A2	161	adaptor-related protein complex 2, alpha 2 subunit	endocytic vesicle membrane	Cellular component	-
SGPL1	8879	sphingosine-1-phosphate lyase 1	carboxy-lyase activity	Molecular function	-
FZD7	8324	frizzled class receptor 7	integral component of membrane	Cellular component	9707618
TGFB1	7040	transforming growth factor, beta 1	negative regulation of myoblast differentiation	Biological process	9770491
CITED1	4435	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1	co-SMAD binding	Molecular function	9707553
NOD1	10392	nucleotide-binding oligomerization domain containing 1	nucleotide-binding oligomerization domain containing signaling pathway	Biological process	-
SLC40A1	30061	solute carrier family 40 (iron-regulated transporter), member 1	iron ion transmembrane transport	Biological process	12091367
PAX6	5080	paired box 6	cellular response to prostaglandin E stimulus	Biological process	-
OAS3	4940	2'-5'-oligoadenylate synthetase 3, 100kDa	cytosol	Cellular component	-
IL20	50604	interleukin 20	immune response	Biological process	-
APOA5	116519	apolipoprotein A-V	enzyme activator activity	Molecular function	16806135
SNRPE	6635	small nuclear ribonucleoprotein polypeptide E	methylosome	Cellular component	18984161
NLRP5	126206	NLR family, pyrin domain containing 5	neuron death	Biological process	22166940
SLC34A2	10568	solute carrier family 34 (type II sodium/phosphate cotransporter), member 2	sodium-dependent phosphate transport	Biological process	-
CXCL14	9547	chemokine (C-X-C motif) ligand 14	inner ear development	Biological process	-
OR2J3	442186	olfactory receptor, family 2, subfamily J, member 3	G-protein coupled receptor signaling pathway	Biological process	-
PCDHGB4	8641	protocadherin gamma subfamily B, 4	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	Biological process	9199196
RARB	5915	retinoic acid receptor, beta	striatum development	Biological process	-
ARHGDIG	398	Rho GDP dissociation inhibitor (GDI) gamma	Rho GDP-dissociation inhibitor activity	Molecular function	-
NIPAL1	152519	NIPA-like domain containing 1	integral component of membrane	Cellular component	-
SLC30A8	169026	solute carrier family 30 (zinc transporter), member 8	response to interleukin-1	Biological process	-
MANF	7873	mesencephalic astrocyte-derived neurotrophic factor	perinuclear region of cytoplasm	Cellular component	-
SLC34A3	142680	solute carrier family 34 (type II sodium/phosphate cotransporter), member 3	apical plasma membrane	Cellular component	11880379
ZFAND6	54469	zinc finger, AN1-type domain 6	DNA binding	Molecular function	-
MYOCD	93649	myocardin	vasculogenesis	Biological process	-
COL6A5	256076	collagen, type VI, alpha 5	extracellular region	Cellular component	-
SFTPC	6440	surfactant protein C	alveolar lamellar body	Cellular component	-
MORC2	22880	MORC family CW-type zinc finger 2	nucleoplasm	Cellular component	-
VAMP8	8673	vesicle-associated membrane protein 8	eosinophil degranulation	Biological process	16677249
TPK1	27010	thiamin pyrophosphokinase 1	cytosol	Cellular component	-
CDC42EP1	11135	CDC42 effector protein (Rho GTPase binding) 1	GTP-Rho binding	Molecular function	-
PRCP	5547	prolylcarboxypeptidase (angiotensinase C)	extracellular exosome	Cellular component	19056867
F2	2147	coagulation factor II (thrombin)	positive regulation of release of sequestered calcium ion into cytosol	Biological process	1672265
CRH	1392	corticotropin releasing hormone	extracellular region	Cellular component	-
NBEA	26960	neurobeachin	trans-Golgi network	Cellular component	-
ARHGAP21	57584	Rho GTPase activating protein 21	cytoplasmic vesicle membrane	Cellular component	-
OPRD1	4985	opioid receptor, delta 1	G-protein coupled receptor signaling pathway	Biological process	16325578
PRM1	5619	protamine 1	cell differentiation	Biological process	-
CA14	23632	carbonic anhydrase XIV	plasma membrane	Cellular component	-
RAC1	5879	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	neurotrophin TRK receptor signaling pathway	Biological process	-
OR6N2	81442	olfactory receptor, family 6, subfamily N, member 2	transmembrane signaling receptor activity	Molecular function	-
OXSR1	9943	oxidative stress responsive 1	negative regulation of rubidium ion transmembrane transporter activity	Biological process	-
RPL38	6169	ribosomal protein L38	sensory perception of sound	Biological process	-
APOE	348	apolipoprotein E	positive regulation of membrane protein ectodomain proteolysis	Biological process	15950758
PPP5C	5536	protein phosphatase 5, catalytic subunit	positive regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	12761501
RTN2	6253	reticulon 2	endoplasmic reticulum	Cellular component	22232211
ATR	545	ATR serine/threonine kinase	regulation of cellular response to heat	Biological process	-
FABP3	2170	fatty acid binding protein 3, muscle and heart	positive regulation of phospholipid biosynthetic process	Biological process	3421901
ULK1	8408	unc-51 like autophagy activating kinase 1	neuron projection regeneration	Biological process	-
PON3	5446	paraoxonase 3	intracellular membrane-bounded organelle	Cellular component	-
PANX3	116337	pannexin 3	transmembrane transport	Biological process	-
UMPS	7372	uridine monophosphate synthetase	female pregnancy	Biological process	-
LDLR	3949	low density lipoprotein receptor	viral process	Biological process	-
CDCA5	113130	cell division cycle associated 5	mitotic chromosome condensation	Biological process	15837422
GAD1	2571	glutamate decarboxylase 1 (brain, 67kDa)	glutamate decarboxylase activity	Molecular function	-
ADAMTS13	11093	ADAM metallopeptidase with thrombospondin type 1 motif, 13	cellular protein metabolic process	Biological process	-
STK31	56164	serine/threonine kinase 31	protein phosphorylation	Biological process	-
ELOVL7	79993	ELOVL fatty acid elongase 7	triglyceride biosynthetic process	Biological process	-
TRAF6	7189	TNF receptor-associated factor 6, E3 ubiquitin protein ligase	positive regulation of transcription regulatory region DNA binding	Biological process	11751921
EXOSC9	5393	exosome component 9	nucleus	Cellular component	-
NPR1	4881	natriuretic peptide receptor 1	positive regulation of renal sodium excretion	Biological process	14960748
ABCB7	22	ATP-binding cassette, sub-family B (MDR/TAP), member 7	mitochondrion	Cellular component	-
LONRF1	91694	LON peptidase N-terminal domain and ring finger 1	proteolysis	Biological process	-
PSMB8	5696	proteasome (prosome, macropain) subunit, beta type, 8	proteasomal ubiquitin-independent protein catabolic process	Biological process	-
ACAD11	84129	acyl-CoA dehydrogenase family, member 11	flavin adenine dinucleotide binding	Molecular function	-
RACGAP1	29127	Rac GTPase activating protein 1	small GTPase mediated signal transduction	Biological process	-
ESR2	2100	estrogen receptor 2 (ER beta)	epithelial cell maturation involved in prostate gland development	Biological process	-
MRPS11	64963	mitochondrial ribosomal protein S11	mitochondrial translational initiation	Biological process	-
GP6	51206	glycoprotein VI (platelet)	protein binding	Molecular function	1715582
TMPRSS3	64699	transmembrane protease, serine 3	integral component of membrane	Cellular component	11068177
SKI	6497	SKI proto-oncogene	cell proliferation	Biological process	14583455
AXIN2	8313	axin 2	postsynaptic density	Cellular component	-
BCL3	602	B-cell CLL/lymphoma 3	response to UV-C	Biological process	16384933
ADCYAP1R1	117	adenylate cyclase activating polypeptide 1 (pituitary) receptor type I	positive regulation of calcium ion transport into cytosol	Biological process	-
ELAC1	55520	elaC ribonuclease Z 1	3'-tRNA processing endoribonuclease activity	Molecular function	-
LRRC40	55631	leucine rich repeat containing 40	membrane	Cellular component	19946888
FLT3	2322	fms-related tyrosine kinase 3	cellular response to glucocorticoid stimulus	Biological process	-
CCR6	1235	chemokine (C-C motif) receptor 6	cellular defense response	Biological process	10521347
LIMK1	3984	LIM domain kinase 1	actin cytoskeleton organization	Biological process	10428028
YWHAZ	7534	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta	mitochondrion	Cellular component	-
WFDC2	10406	WAP four-disulfide core domain 2	extracellular exosome	Cellular component	23376485
HMG20B	10362	high mobility group 20B	chromosome	Cellular component	-
DCTN2	10540	dynactin 2 (p50)	metabolic process	Biological process	-
SERPINA1	5265	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1	Golgi apparatus	Cellular component	20477988
HLA-DPB1	3115	major histocompatibility complex, class II, DP beta 1	plasma membrane	Cellular component	-
KIF26A	26153	kinesin family member 26A	microtubule motor activity	Molecular function	-
MARCKS	4082	myristoylated alanine-rich protein kinase C substrate	actin filament binding	Molecular function	1560845
ZNF81	347344	zinc finger protein 81	DNA binding	Molecular function	-
FAM132A	388581	family with sequence similarity 132, member A	positive regulation of insulin secretion involved in cellular response to glucose stimulus	Biological process	-
UCK2	7371	uridine-cytidine kinase 2	phosphorylation	Biological process	-
AXIN1	8312	axin 1	positive regulation of ubiquitin-protein transferase activity	Biological process	16601693
MRPL55	128308	mitochondrial ribosomal protein L55	mitochondrial translation	Biological process	-
ACSL6	23305	acyl-CoA synthetase long-chain family member 6	peroxisomal membrane	Cellular component	-
PELI1	57162	pellino E3 ubiquitin protein ligase 1	toll-like receptor signaling pathway	Biological process	-
TARSL2	123283	threonyl-tRNA synthetase-like 2	threonyl-tRNA aminoacylation	Biological process	-
SH3BGR	6450	SH3 domain binding glutamate-rich protein	protein complex assembly	Biological process	9050928
LRPAP1	4043	low density lipoprotein receptor-related protein associated protein 1	extracellular region	Cellular component	8083232
SFRP1	6422	secreted frizzled-related protein 1	negative regulation of fibroblast proliferation	Biological process	19734317
STAT4	6775	signal transducer and activator of transcription 4	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
GRIK3	2899	glutamate receptor, ionotropic, kainate 3	cell junction	Cellular component	-
RIPK3	11035	receptor-interacting serine-threonine kinase 3	protein binding	Molecular function	19524512
AVPR1A	552	arginine vasopressin receptor 1A	positive regulation of prostaglandin biosynthetic process	Biological process	-
BRAF	673	B-Raf proto-oncogene, serine/threonine kinase	protein heterooligomerization	Biological process	-
CAV3	859	caveolin 3	regulation of cardiac muscle contraction	Biological process	17275750
CHAC1	79094	ChaC glutathione-specific gamma-glutamylcyclotransferase 1	Notch signaling pathway	Biological process	-
CEBPG	1054	CCAAT/enhancer binding protein (C/EBP), gamma	positive regulation of transcription from RNA polymerase II promoter	Biological process	15833715
IGF1	3479	insulin-like growth factor 1 (somatomedin C)	positive regulation of tyrosine phosphorylation of Stat5 protein	Biological process	9722506
RAPGEF2	9693	Rap guanine nucleotide exchange factor (GEF) 2	synapse	Cellular component	-
CHP2	63928	calcineurin-like EF-hand protein 2	protein transport	Biological process	-
PDGFRA	5156	platelet-derived growth factor receptor, alpha polypeptide	vascular endothelial growth factor-activated receptor activity	Molecular function	17470632
PGAM5	192111	phosphoglycerate mutase family member 5	phosphatase activity	Molecular function	22265414
NOBOX	135935	NOBOX oogenesis homeobox	transcription, DNA-templated	Biological process	-
ATP6V1G1	9550	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1	insulin receptor signaling pathway	Biological process	-
UCK2	7371	uridine-cytidine kinase 2	response to axon injury	Biological process	-
LSM3	27258	LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)	poly(A) RNA binding	Molecular function	22658674
PRSS2	5645	protease, serine, 2 (trypsin 2)	innate immune response	Biological process	-
SART3	9733	squamous cell carcinoma antigen recognized by T cells 3	nucleotide binding	Molecular function	-
SLC1A2	6506	solute carrier family 1 (glial high affinity glutamate transporter), member 2	protein binding	Molecular function	19527721
ZDHHC20	253832	zinc finger, DHHC-type containing 20	plasma membrane	Cellular component	16647879
TXNDC11	51061	thioredoxin domain containing 11	integral component of membrane	Cellular component	-
PSMB11	122706	proteasome (prosome, macropain) subunit, beta type, 11	regulation of apoptotic process	Biological process	-
REXO4	57109	REX4, RNA exonuclease 4 homolog (S. cerevisiae)	sequence-specific DNA binding transcription factor activity	Molecular function	10908561
PHB	5245	prohibitin	mitochondrion organization	Biological process	17008324
IDH3G	3421	isocitrate dehydrogenase 3 (NAD+) gamma	ATP binding	Molecular function	-
CCRN4L	25819	CCR4 carbon catabolite repression 4-like (S. cerevisiae)	metal ion binding	Molecular function	-
ACOT4	122970	acyl-CoA thioesterase 4	succinyl-CoA metabolic process	Biological process	16940157
MERTK	10461	MER proto-oncogene, tyrosine kinase	protein binding	Molecular function	20103767
AP3B2	8120	adaptor-related protein complex 3, beta 2 subunit	clathrin-coated vesicle membrane	Cellular component	-
T	6862	T, brachyury homolog (mouse)	post-anal tail morphogenesis	Biological process	-
DLG2	1740	discs, large homolog 2 (Drosophila)	receptor clustering	Biological process	-
BTC	685	betacellulin	protein binding	Molecular function	19740107
STAU1	6780	staufen double-stranded RNA binding protein 1	dendrite	Cellular component	15121898
SHOX2	6474	short stature homeobox 2	sequence-specific DNA binding	Molecular function	-
SP3	6670	Sp3 transcription factor	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
NOC2L	26155	nucleolar complex associated 2 homolog (S. cerevisiae)	negative regulation of intrinsic apoptotic signaling pathway	Biological process	16322561
CACNA1D	776	calcium channel, voltage-dependent, L type, alpha 1D subunit	regulation of potassium ion transmembrane transport	Biological process	-
ATAD2B	54454	ATPase family, AAA domain containing 2B	metabolic process	Biological process	-
CNTNAP3	79937	contactin associated protein-like 3	extracellular region	Cellular component	-
PARP6	56965	poly (ADP-ribose) polymerase family, member 6	NAD+ ADP-ribosyltransferase activity	Molecular function	-
CACNA1B	774	calcium channel, voltage-dependent, N type, alpha 1B subunit	regulation of blood pressure	Biological process	-
ICK	22858	intestinal cell (MAK-like) kinase	protein phosphorylation	Biological process	10699974
LSR	51599	lipolysis stimulated lipoprotein receptor	extracellular exosome	Cellular component	19199708
PLAGL1	5325	pleiomorphic adenoma gene-like 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	15888726
CASP2	835	caspase 2, apoptosis-related cysteine peptidase	cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Molecular function	-
CASP8AP2	9994	caspase 8 associated protein 2	signal transduction	Biological process	10235259
MTOR	2475	mechanistic target of rapamycin (serine/threonine kinase)	ATP binding	Molecular function	-
WIBG	84305	within bgcn homolog (Drosophila)	protein binding	Molecular function	18026120
FGF22	27006	fibroblast growth factor 22	fibroblast growth factor receptor signaling pathway	Biological process	-
KLF1	10661	Kruppel-like factor 1 (erythroid)	transcription regulatory region DNA binding	Molecular function	20676099
DPCD	25911	deleted in primary ciliary dyskinesia homolog (mouse)	protein binding	Molecular function	16189514
FGF8	2253	fibroblast growth factor 8 (androgen-induced)	subpallium development	Biological process	-
LARP1	23367	La ribonucleoprotein domain family, member 1	poly(A) RNA binding	Molecular function	22658674
ZBP1	81030	Z-DNA binding protein 1	metabolic process	Biological process	-
VAPA	9218	VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa	endoplasmic reticulum organization	Biological process	18713837
EHMT2	10919	euchromatic histone-lysine N-methyltransferase 2	p53 binding	Molecular function	20118233
APOA1	335	apolipoprotein A-I	response to nutrient	Biological process	-
SCNN1G	6340	sodium channel, non voltage gated 1 gamma subunit	sodium ion transport	Biological process	8521520
DIO1	1733	deiodinase, iodothyronine, type I	hormone biosynthetic process	Biological process	-
KPNA2	3838	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	cytoplasm	Cellular component	-
TLR6	10333	toll-like receptor 6	lipopeptide binding	Molecular function	11431423
TRIM28	10155	tripartite motif containing 28	protein ubiquitination	Biological process	18082607
AKR1C4	1109	aldo-keto reductase family 1, member C4	aldo-keto reductase (NADP) activity	Molecular function	7650035
CYBA	1535	cytochrome b-245, alpha polypeptide	positive regulation of phagocytosis	Biological process	22423966
MEMO1	51072	mediator of cell motility 1	cytosol	Cellular component	16780588
MTRR	4552	5-methyltetrahydrofolate-homocysteine methyltransferase reductase	aquacobalamin reductase (NADPH) activity	Molecular function	16769880
NLRP6	171389	NLR family, pyrin domain containing 6	ATP binding	Molecular function	-
HOXB2	3212	homeobox B2	rhombomere 4 development	Biological process	-
ADPRH	141	ADP-ribosylarginine hydrolase	protein de-ADP-ribosylation	Biological process	-
HSF1	3297	heat shock transcription factor 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	10561509
RELA	5970	v-rel avian reticuloendotheliosis viral oncogene homolog A	innate immune response	Biological process	-
NCOA3	8202	nuclear receptor coactivator 3	histone acetyltransferase activity	Molecular function	9267036
IL6ST	3572	interleukin 6 signal transducer	leukemia inhibitory factor receptor activity	Molecular function	12643274
PRKAA1	5562	protein kinase, AMP-activated, alpha 1 catalytic subunit	regulation of transcription, DNA-templated	Biological process	-
KIF13A	63971	kinesin family member 13A	midbody	Cellular component	20208530
LAMA4	3910	laminin, alpha 4	extracellular exosome	Cellular component	19199708
SLX1A	548593	SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)	crossover junction endodeoxyribonuclease activity	Molecular function	19595721
CREB3L3	84699	cAMP responsive element binding protein 3-like 3	protein homodimerization activity	Molecular function	16469704
AQP2	359	aquaporin 2 (collecting duct)	glycerol transport	Biological process	8584435
AQP9	366	aquaporin 9	integral component of membrane	Cellular component	9733774
MYF6	4618	myogenic factor 6 (herculin)	somitogenesis	Biological process	-
KIF5B	3799	kinesin family member 5B	microtubule motor activity	Molecular function	-
ERVK-16	100616411	endogenous retrovirus group K, member 16	RNA binding	Molecular function	-
DKK4	27121	dickkopf WNT signaling pathway inhibitor 4	molecular_function	Molecular function	-
P2RX3	5024	purinergic receptor P2X, ligand gated ion channel, 3	transport	Biological process	9221902
CCL25	6370	chemokine (C-C motif) ligand 25	extracellular space	Cellular component	-
PFDN4	5203	prefoldin subunit 4	cellular protein metabolic process	Biological process	-
FGFR3	2261	fibroblast growth factor receptor 3	positive regulation of phosphatidylinositol 3-kinase activity	Biological process	15748888
FAM90A12P	645879	Putative protein FAM90A12	nucleic acid binding	Molecular function	-
ARHGDIA	396	Rho GDP dissociation inhibitor (GDI) alpha	extracellular exosome	Cellular component	19056867
GNGT2	2793	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2	metabolic process	Biological process	9286705
ITGA5	3678	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	positive regulation of vascular endothelial growth factor receptor signaling pathway	Biological process	19267251
CASR	846	calcium-sensing receptor	ossification	Biological process	7874174
MIF	4282	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	cytokine receptor binding	Molecular function	17045821
LRP6	4040	low density lipoprotein receptor-related protein 6	heart looping	Biological process	-
DHRS9	10170	dehydrogenase/reductase (SDR family) member 9	alcohol dehydrogenase (NAD) activity	Molecular function	11304534
PTK2B	2185	protein tyrosine kinase 2 beta	neuronal cell body	Cellular component	-
CDA	978	cytidine deaminase	zinc ion binding	Molecular function	9596658
CEP250	11190	centrosomal protein 250kDa	perinuclear region of cytoplasm	Cellular component	-
LEMD1	93273	LEM domain containing 1	integral component of membrane	Cellular component	-
OR2D3	120775	olfactory receptor, family 2, subfamily D, member 3	G-protein coupled receptor activity	Molecular function	-
ANGPTL3	27329	angiopoietin-like 3	cholesterol homeostasis	Biological process	17110602
TMEM132D	121256	transmembrane protein 132D	protein binding	Molecular function	19389623
DAPK1	1612	death-associated protein kinase 1	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	Biological process	-
CCL4	6351	chemokine (C-C motif) ligand 4	extracellular space	Cellular component	-
ADCY9	115	adenylate cyclase 9	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway	Biological process	-
CYP2W1	54905	cytochrome P450, family 2, subfamily W, polypeptide 1	steroid hydroxylase activity	Molecular function	-
LMNA	4000	lamin A/C	nuclear membrane	Cellular component	16791210
DNM1	1759	dynamin 1	protein binding	Molecular function	10206341
OR5B21	219968	olfactory receptor, family 5, subfamily B, member 21	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
GPLD1	2822	glycosylphosphatidylinositol specific phospholipase D1	proteinaceous extracellular matrix	Cellular component	-
OLIG2	10215	oligodendrocyte lineage transcription factor 2	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
PDP1	54704	pyruvate dehyrogenase phosphatase catalytic subunit 1	mitochondrial matrix	Cellular component	-
PPP1R2	5504	protein phosphatase 1, regulatory (inhibitor) subunit 2	protein binding	Molecular function	10807923
POLI	11201	polymerase (DNA directed) iota	nucleus	Cellular component	-
LPAR2	9170	lysophosphatidic acid receptor 2	G-protein coupled receptor signaling pathway	Biological process	-
CD80	941	CD80 molecule	intracellular	Cellular component	-
NR3C1	2908	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	maternal behavior	Biological process	-
MYH6	4624	myosin, heavy chain 6, cardiac muscle, alpha	muscle filament sliding	Biological process	-
LRRC16A	55604	leucine rich repeat containing 16A	nucleus	Cellular component	-
NR1H3	10062	nuclear receptor subfamily 1, group H, member 3	nucleoplasm	Cellular component	-
GLRX	2745	glutaredoxin (thioltransferase)	small molecule metabolic process	Biological process	-
GDF3	9573	growth differentiation factor 3	regulation of cell fate commitment	Biological process	18823971
NPC1	4864	Niemann-Pick disease, type C1	autophagy	Biological process	19074461
OR2A4	79541	olfactory receptor, family 2, subfamily A, member 4	recycling endosome	Cellular component	22888021
RAB27A	5873	RAB27A, member RAS oncogene family	exocytosis	Biological process	18812475
SFMBT2	57713	Scm-like with four mbt domains 2	aggresome	Cellular component	-
TMPRSS6	164656	transmembrane protease, serine 6	plasma membrane	Cellular component	19357398
BMP2	650	bone morphogenetic protein 2	negative regulation of calcium-independent cell-cell adhesion	Biological process	16194878
AGL	178	amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase	small molecule metabolic process	Biological process	-
DNMT3A	1788	DNA (cytosine-5-)-methyltransferase 3 alpha	DNA (cytosine-5-)-methyltransferase activity	Molecular function	12138111
FYB	2533	FYN binding protein	NLS-bearing protein import into nucleus	Biological process	9207119
DNAJA4	55466	DnaJ (Hsp40) homolog, subfamily A, member 4	ATP binding	Molecular function	-
GPD1L	23171	glycerol-3-phosphate dehydrogenase 1-like	regulation of ventricular cardiac muscle cell membrane depolarization	Biological process	17967977
BLMH	642	bleomycin hydrolase	cytosol	Cellular component	-
STK4	6789	serine/threonine kinase 4	central nervous system development	Biological process	-
RPL7	6129	ribosomal protein L7	translational termination	Biological process	-
CARTPT	9607	CART prepropeptide	secretory granule	Cellular component	21624661
E2F1	1869	E2F transcription factor 1	intrinsic apoptotic signaling pathway by p53 class mediator	Biological process	-
CYP27C1	339761	cytochrome P450, family 27, subfamily C, polypeptide 1	iron ion binding	Molecular function	-
NKX2-5	1482	NK2 homeobox 5	RNA polymerase II transcription factor complex	Cellular component	9312027
ZDHHC15	158866	zinc finger, DHHC-type containing 15	zinc ion binding	Molecular function	-
MYPN	84665	myopalladin	Z disc	Cellular component	11309420
IL4	3565	interleukin 4	interleukin-4 receptor binding	Molecular function	11418631
CETP	1071	cholesteryl ester transfer protein, plasma	very-low-density lipoprotein particle remodeling	Biological process	24293641
MFF	56947	mitochondrial fission factor	mitochondrial fragmentation involved in apoptotic process	Biological process	18353969
MYL3	4634	myosin, light chain 3, alkali; ventricular, skeletal, slow	calcium ion binding	Molecular function	-
ST6GAL1	6480	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1	protein binding	Molecular function	16237761
GATA3	2625	GATA binding protein 3	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	19674970
NUP160	23279	nucleoporin 160kDa	nuclear pore	Cellular component	11564755
LPIN1	23175	lipin 1	cellular lipid metabolic process	Biological process	-
IFT140	9742	intraflagellar transport 140	ciliary tip	Cellular component	-
IGSF9	57549	immunoglobulin superfamily, member 9	dendrite development	Biological process	-
TNFRSF10A	8797	tumor necrosis factor receptor superfamily, member 10a	signal transduction	Biological process	9082980
SSTR2	6752	somatostatin receptor 2	peristalsis	Biological process	-
LEF1	51176	lymphoid enhancer-binding factor 1	hypothalamus development	Biological process	-
RPL11	6135	ribosomal protein L11	cytosol	Cellular component	-
EEF1A1P5	158078	eukaryotic translation elongation factor 1 alpha 1 pseudogene 5	molecular_function	Molecular function	-
CTTN	2017	cortactin	protein binding	Molecular function	15169891
CER1	9350	cerberus 1, DAN family BMP antagonist	morphogen activity	Molecular function	9660951
MYH2	4620	myosin, heavy chain 2, skeletal muscle, adult	ATP binding	Molecular function	-
S100A7	6278	S100 calcium binding protein A7	epidermis development	Biological process	1940442
NDEL1	81565	nudE neurodevelopment protein 1-like 1	microtubule binding	Molecular function	-
BBS9	27241	Bardet-Biedl syndrome 9	response to stimulus	Biological process	-
DRAM1	55332	DNA-damage regulated autophagy modulator 1	integral component of membrane	Cellular component	-
CCDC6	8030	coiled-coil domain containing 6	biological_process	Biological process	-
CD3EAP	10849	CD3e molecule, epsilon associated protein	mitochondrion	Cellular component	-
PROX1	5629	prospero homeobox 1	skeletal muscle thin filament assembly	Biological process	-
CC2D2A	57545	coiled-coil and C2 domain containing 2A	cytoskeleton	Cellular component	-
UHRF1	29128	ubiquitin-like with PHD and ring finger domains 1	positive regulation of cellular protein metabolic process	Biological process	10646863
ADAM10	102	ADAM metallopeptidase domain 10	positive regulation of T cell chemotaxis	Biological process	18373975
KIF5C	3800	kinesin family member 5C	microtubule binding	Molecular function	-
PCM1	5108	pericentriolar material 1	cilium assembly	Biological process	15616553
HEG1	57493	heart development protein with EGF-like domains 1	multicellular organism growth	Biological process	-
HIF1A	3091	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	regulation of transcription from RNA polymerase II promoter in response to hypoxia	Biological process	-
PPP1R15B	84919	protein phosphatase 1, regulatory subunit 15B	protein phosphatase type 1 complex	Cellular component	-
ATPIF1	93974	ATPase inhibitory factor 1	activation of mitophagy in response to mitochondrial depolarization	Biological process	24005319
SUN1	23353	Sad1 and UNC84 domain containing 1	nuclear matrix anchoring at nuclear membrane	Biological process	18396275
PTPRD	5789	protein tyrosine phosphatase, receptor type, D	protein dephosphorylation	Biological process	7896816
AKT1	207	v-akt murine thymoma viral oncogene homolog 1	cellular response to mechanical stimulus	Biological process	-
ANXA5	308	annexin A5	extracellular exosome	Cellular component	19056867
FOXA1	3169	forkhead box A1	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	Biological process	-
MMP2	4313	matrix metallopeptidase 2	axon guidance	Biological process	-
NRAP	4892	nebulin-related anchoring protein	muscle alpha-actinin binding	Molecular function	-
B3GNT4	79369	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4	O-glycan processing	Biological process	-
HAP1	9001	huntingtin-associated protein 1	actin cytoskeleton	Cellular component	9361024
SPNS2	124976	spinster homolog 2 (Drosophila)	vesicle	Cellular component	-
LGALS3BP	3959	lectin, galactoside-binding, soluble, 3 binding protein	proteinaceous extracellular matrix	Cellular component	-
PAPD5	64282	PAP associated domain containing 5	DNA biosynthetic process	Biological process	-
CHUK	1147	conserved helix-loop-helix ubiquitous kinase	protein homodimerization activity	Molecular function	23091055
TYROBP	7305	TYRO protein tyrosine kinase binding protein	protein binding	Molecular function	10940905
NTRK3	4916	neurotrophic tyrosine kinase, receptor, type 3	cellular response to retinoic acid	Biological process	-
STUB1	10273	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase	Hsp90 protein binding	Molecular function	11146632
DHX36	170506	DEAH (Asp-Glu-Ala-His) box polypeptide 36	DNA-dependent ATPase activity	Molecular function	21586581
CCNA2	890	cyclin A2	cell division	Biological process	-
GIPR	2696	gastric inhibitory polypeptide receptor	response to glucose	Biological process	-
TCF7L1	83439	transcription factor 7-like 1 (T-cell specific, HMG-box)	regulation of transcription from RNA polymerase II promoter	Biological process	-
GPI	2821	glucose-6-phosphate isomerase	intramolecular transferase activity	Molecular function	-
LRP4	4038	low density lipoprotein receptor-related protein 4	canonical Wnt signaling pathway	Biological process	-
ADRB2	154	adrenoceptor beta 2, surface	protein binding	Molecular function	15123695
PAN3	255967	PAN3 poly(A) specific ribonuclease subunit	RNA phosphodiester bond hydrolysis, exonucleolytic	Biological process	14583602
CPLX4	339302	complexin 4	cell junction	Cellular component	-
CAP1	10487	CAP, adenylate cyclase-associated protein 1 (yeast)	establishment or maintenance of cell polarity	Biological process	1406678
WHSC1	7468	Wolf-Hirschhorn syndrome candidate 1	histone-lysine N-methyltransferase activity	Molecular function	-
IL3	3562	interleukin 3	positive regulation of cell proliferation	Biological process	-
RPS27A	6233	ribosomal protein S27a	glycogen biosynthetic process	Biological process	-
OAZ3	51686	ornithine decarboxylase antizyme 3	protein binding	Molecular function	17900240
KLF4	9314	Kruppel-like factor 4 (gut)	negative regulation of chemokine (C-X-C motif) ligand 2 production	Biological process	20551324
SLC9A3R1	9368	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1	regulation of excretion	Biological process	-
RPS19	6223	ribosomal protein S19	fibroblast growth factor binding	Molecular function	11716516
HERC2	8924	HECT and RLD domain containing E3 ubiquitin protein ligase 2	ubiquitin protein ligase binding	Molecular function	22508508
KCNIP1	30820	Kv channel interacting protein 1	extrinsic component of cytoplasmic side of plasma membrane	Cellular component	10676964
IFIT2	3433	interferon-induced protein with tetratricopeptide repeats 2	protein binding	Molecular function	19416887
ROR2	4920	receptor tyrosine kinase-like orphan receptor 2	cartilage condensation	Biological process	-
AURKA	6790	aurora kinase A	pronucleus	Cellular component	-
SH2B2	10603	SH2B adaptor protein 2	blood coagulation	Biological process	-
PAPD5	64282	PAP associated domain containing 5	metal ion binding	Molecular function	-
TMEM186	25880	transmembrane protein 186	mitochondrion	Cellular component	-
CASP3	836	caspase 3, apoptosis-related cysteine peptidase	release of cytochrome c from mitochondria	Biological process	-
TANK	10010	TRAF family member-associated NFKB activator	protein binding	Molecular function	12005438
PCYT1A	5130	phosphate cytidylyltransferase 1, choline, alpha	CDP-choline pathway	Biological process	-
JAG1	182	jagged 1	ciliary body morphogenesis	Biological process	-
BMP4	652	bone morphogenetic protein 4	lung morphogenesis	Biological process	8674409
FBXW7	55294	F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase	positive regulation of protein targeting to mitochondrion	Biological process	24912190
JAK2	3717	Janus kinase 2	type 1 angiotensin receptor binding	Molecular function	-
APAF1	317	apoptotic peptidase activating factor 1	identical protein binding	Molecular function	-
RUNX1T1	862	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	protein binding	Molecular function	10973986
NSMF	26012	NMDA receptor synaptonuclear signaling and neuronal migration factor	apical dendrite	Cellular component	-
IRF3	3661	interferon regulatory factor 3	lipopolysaccharide-mediated signaling pathway	Biological process	-
SULT1E1	6783	sulfotransferase family 1E, estrogen-preferring, member 1	steroid binding	Molecular function	-
NUP62	23636	nucleoporin 62kDa	negative regulation of Ras protein signal transduction	Biological process	-
CBFB	865	core-binding factor, beta subunit	protein polyubiquitination	Biological process	22190036
POLD4	57804	polymerase (DNA-directed), delta 4, accessory subunit	base-excision repair	Biological process	-
TOP2B	7155	topoisomerase (DNA) II beta 180kDa	DNA topological change	Biological process	10684600
IL20RB	53833	interleukin 20 receptor beta	cytokine receptor activity	Molecular function	-
MED20	9477	mediator complex subunit 20	transcription initiation from RNA polymerase II promoter	Biological process	-
HNRNPUL1	11100	heterogeneous nuclear ribonucleoprotein U-like 1	mRNA splicing, via spliceosome	Biological process	-
NRD1	4898	nardilysin (N-arginine dibasic convertase)	cell surface	Cellular component	12463163
SMARCC1	6599	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	nucleoplasm	Cellular component	-
TC2N	123036	tandem C2 domains, nuclear	molecular_function	Molecular function	-
ZNF43	7594	zinc finger protein 43	DNA binding	Molecular function	-
ODF2	4957	outer dense fiber of sperm tails 2	centriole	Cellular component	17646400
SRF	6722	serum response factor (c-fos serum response element-binding transcription factor)	cellular response to glucose stimulus	Biological process	-
ANXA2	302	annexin A2	lipid particle	Cellular component	14741744
PAX2	5076	paired box 2	pancreas development	Biological process	-
DHRS3	9249	dehydrogenase/reductase (SDR family) member 3	endoplasmic reticulum membrane	Cellular component	-
TRIM5	85363	tripartite motif containing 5	identical protein binding	Molecular function	22493164
ARAP1	116985	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1	plasma membrane	Cellular component	-
CDH6	1004	cadherin 6, type 2, K-cadherin (fetal kidney)	cell junction assembly	Biological process	-
YIF1A	10897	Yip1 interacting factor homolog A (S. cerevisiae)	cellular protein metabolic process	Biological process	-
ANKH	56172	ANKH inorganic pyrophosphate transport regulator	integral component of plasma membrane	Cellular component	-
NOG	9241	noggin	positive regulation of epithelial cell proliferation	Biological process	-
PTPRO	5800	protein tyrosine phosphatase, receptor type, O	axon	Cellular component	-
MTCL1	23255	microtubule crosslinking factor 1	poly(A) RNA binding	Molecular function	22658674
NOS2	4843	nitric oxide synthase 2, inducible	arginine binding	Molecular function	-
COPS8	10920	COP9 signalosome subunit 8	nucleoplasm	Cellular component	-
HLCS	3141	holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)	protein homodimerization activity	Molecular function	-
PLEKHF1	79156	pleckstrin homology domain containing, family F (with FYVE domain) member 1	phosphatidylinositol-3-phosphate binding	Molecular function	22115783
IL18	3606	interleukin 18	extracellular exosome	Cellular component	23376485
TUBB2B	347733	tubulin, beta 2B class IIb	microtubule	Cellular component	21525035
CYP26A1	1592	cytochrome P450, family 26, subfamily A, polypeptide 1	negative regulation of retinoic acid receptor signaling pathway	Biological process	14532297
STAT5A	6776	signal transducer and activator of transcription 5A	mammary gland epithelium development	Biological process	-
HUS1	3364	HUS1 checkpoint homolog (S. pombe)	cellular response to DNA damage stimulus	Biological process	9872989
ITPR1	3708	inositol 1,4,5-trisphosphate receptor, type 1	blood coagulation	Biological process	-
NCOA1	8648	nuclear receptor coactivator 1	enzyme binding	Molecular function	12039952
PDCD6	10016	programmed cell death 6	positive regulation of endothelial cell proliferation	Biological process	21893193
RPS2	6187	ribosomal protein S2	protein binding	Molecular function	15473865
BGLAP	632	bone gamma-carboxyglutamate (gla) protein	response to vitamin K	Biological process	-
NAPSA	9476	napsin A aspartic peptidase	endopeptidase activity	Molecular function	14766755
ZNF281	23528	zinc finger protein 281	stem cell differentiation	Biological process	-
CTLA4	1493	cytotoxic T-lymphocyte-associated protein 4	Golgi apparatus	Cellular component	15814706
SPPL2C	162540	signal peptide peptidase like 2C	integral component of lumenal side of endoplasmic reticulum membrane	Cellular component	15385547
WDR18	57418	WD repeat domain 18	protein binding	Molecular function	21326211
SNW1	22938	SNW domain containing 1	positive regulation of mRNA splicing, via spliceosome	Biological process	12840015
TLR3	7098	toll-like receptor 3	cellular response to drug	Biological process	-
CASK	8573	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	cell-cell junction	Cellular component	18664494
SLC6A4	6532	solute carrier family 6 (neurotransmitter transporter), member 4	neuron projection	Cellular component	-
NRG1	3084	neuregulin 1	phosphatidylinositol-mediated signaling	Biological process	-
PTPN22	26191	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	protein binding	Molecular function	10068674
ZNF835	90485	zinc finger protein 835	transcription, DNA-templated	Biological process	-
NLGN1	22871	neuroligin 1	regulation of neuron differentiation	Biological process	-
TOPORS	10210	topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase	zinc ion binding	Molecular function	-
IRF7	3665	interferon regulatory factor 7	regulation of immune response	Biological process	21490621
ACVRL1	94	activin A receptor type II-like 1	blood vessel endothelial cell proliferation involved in sprouting angiogenesis	Biological process	20406889
EREG	2069	epiregulin	positive regulation of mitotic nuclear division	Biological process	-
CFL1	1072	cofilin 1 (non-muscle)	neural fold formation	Biological process	-
ESRRB	2103	estrogen-related receptor beta	nucleoplasm	Cellular component	-
MED16	10025	mediator complex subunit 16	transcription coactivator activity	Molecular function	10198638
B2M	567	beta-2-microglobulin	innate immune response	Biological process	-
SEH1L	81929	SEH1-like (S. cerevisiae)	defense response to Gram-positive bacterium	Biological process	-
NUDT18	79873	nudix (nucleoside diphosphate linked moiety X)-type motif 18	GDP catabolic process	Biological process	22556419
NFATC1	4772	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity	Molecular function	-
ARHGEF10L	55160	Rho guanine nucleotide exchange factor (GEF) 10-like	cytoplasm	Cellular component	-
CHGA	1113	chromogranin A	transport vesicle membrane	Cellular component	-
BNIP3	664	BCL2/adenovirus E1B 19kDa interacting protein 3	cellular response to cobalt ion	Biological process	20436456
MYOG	4656	myogenin (myogenic factor 4)	response to denervation involved in regulation of muscle adaptation	Biological process	-
PPBP	5473	pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)	platelet activation	Biological process	-
NFATC1	4772	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	transcription from RNA polymerase II promoter	Biological process	8702849
GOLPH3	64083	golgi phosphoprotein 3 (coat-protein)	enzyme binding	Molecular function	23027862
UACA	55075	uveal autoantigen with coiled-coil domains and ankyrin repeats	response to UV	Biological process	-
GAS7	8522	growth arrest-specific 7	cell cycle arrest	Biological process	9736752
RHOG	391	ras homolog family member G	plasma membrane	Cellular component	-
ITGA8	8516	integrin, alpha 8	integrin complex	Cellular component	7768999
NAPRT	93100	nicotinate phosphoribosyltransferase	cytoplasm	Cellular component	-
NOS1	4842	nitric oxide synthase 1 (neuronal)	positive regulation of histone acetylation	Biological process	-
NOTCH3	4854	notch 3	cytosol	Cellular component	-
NAPA	8775	N-ethylmaleimide-sensitive factor attachment protein, alpha	syntaxin binding	Molecular function	-
PSD	5662	pleckstrin and Sec7 domain containing	plasma membrane	Cellular component	-
AGO3	192669	argonaute RISC catalytic component 3	Notch signaling pathway	Biological process	-
TAS2R42	353164	taste receptor, type 2, member 42	G-protein coupled receptor signaling pathway	Biological process	-
PHKB	5257	phosphorylase kinase, beta	carbohydrate metabolic process	Biological process	-
PPIA	5478	peptidylprolyl isomerase A (cyclophilin A)	establishment of integrated proviral latency	Biological process	-
GCK	2645	glucokinase (hexokinase 4)	lipid homeostasis	Biological process	-
ALDH1A1	216	aldehyde dehydrogenase 1 family, member A1	androgen binding	Molecular function	1709013
EDN1	1906	endothelin 1	negative regulation of cAMP biosynthetic process	Biological process	-
S100A10	6281	S100 calcium binding protein A10	membrane budding	Biological process	23861394
IGSF5	150084	immunoglobulin superfamily, member 5	single organismal cell-cell adhesion	Biological process	-
BIRC7	79444	baculoviral IAP repeat containing 7	protein ubiquitination	Biological process	16729033
DOPEY2	9980	dopey family member 2	protein transport	Biological process	-
GNAI1	2770	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1	G-protein beta/gamma-subunit complex binding	Molecular function	-
CHEK1	1111	checkpoint kinase 1	nucleus	Cellular component	15311285
GAPDH	2597	glyceraldehyde-3-phosphate dehydrogenase	glucose metabolic process	Biological process	-
SP8	221833	Sp8 transcription factor	DNA binding	Molecular function	-
DGKI	9162	diacylglycerol kinase, iota	diacylglycerol kinase activity	Molecular function	-
PIK3R3	8503	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)	1-phosphatidylinositol-3-kinase activity	Molecular function	9524259
KANK1	23189	KN motif and ankyrin repeat domains 1	negative regulation of substrate adhesion-dependent cell spreading	Biological process	19171758
ERCC5	2073	excision repair cross-complementation group 5	single-stranded DNA binding	Molecular function	12644470
STX8	9482	syntaxin 8	ubiquitin protein ligase binding	Molecular function	-
ITGB1	3688	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	ruffle	Cellular component	11919189
MED19	219541	mediator complex subunit 19	mediator complex	Cellular component	-
RHEBL1	121268	Ras homolog enriched in brain like 1	metal ion binding	Molecular function	-
FEN1	2237	flap structure-specific endonuclease 1	RNA-DNA hybrid ribonuclease activity	Molecular function	7961795
BRAF	673	B-Raf proto-oncogene, serine/threonine kinase	response to peptide hormone	Biological process	-
TBX5	6910	T-box 5	cell-cell signaling	Biological process	11161571
SLC16A1	6566	solute carrier family 16 (monocarboxylate transporter), member 1	leukocyte migration	Biological process	-
TPT1	7178	tumor protein, translationally-controlled 1	response to virus	Biological process	16548883
ZNF43	7594	zinc finger protein 43	metal ion binding	Molecular function	-
ACVR2A	92	activin A receptor, type IIA	inhibin binding	Molecular function	-
POT1	25913	protection of telomeres 1	nuclear telomere cap complex	Cellular component	16880378
OR1S2	219958	olfactory receptor, family 1, subfamily S, member 2	G-protein coupled receptor activity	Molecular function	-
SCARF1	8578	scavenger receptor class F, member 1	positive regulation of neuron projection development	Biological process	-
SLX1A	548593	SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)	5'-flap endonuclease activity	Molecular function	19596235
TBR1	10716	T-box, brain, 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
SGCD	6444	sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)	cardiac muscle tissue development	Biological process	-
IL18	3606	interleukin 18	natural killer cell activation	Biological process	-
MTR	4548	5-methyltetrahydrofolate-homocysteine methyltransferase	nervous system development	Biological process	8968737
VASP	7408	vasodilator-stimulated phosphoprotein	SH3 domain binding	Molecular function	-
PRELP	5549	proline/arginine-rich end leucine-rich repeat protein	lysosomal lumen	Cellular component	-
CEP250	11190	centrosomal protein 250kDa	centriole	Cellular component	11076968
CYP2C9	1559	cytochrome P450, family 2, subfamily C, polypeptide 9	(S)-limonene 6-monooxygenase activity	Molecular function	-
SBF1	6305	SET binding factor 1	positive regulation of GTPase activity	Biological process	-
APOA1	335	apolipoprotein A-I	extracellular vesicle	Cellular component	24769233
DCN	1634	decorin	wound healing	Biological process	-
SSTR4	6754	somatostatin receptor 4	somatostatin receptor activity	Molecular function	-
PRMT1	3276	protein arginine methyltransferase 1	chromatin organization	Biological process	-
TNNC1	7134	troponin C type 1 (slow)	nucleoplasm	Cellular component	-
TRAPPC4	51399	trafficking protein particle complex 4	cis-Golgi network	Cellular component	-
ZFPM1	161882	zinc finger protein, FOG family member 1	nucleus	Cellular component	-
MS4A1	931	membrane-spanning 4-domains, subfamily A, member 1	MHC class II protein complex binding	Molecular function	20458337
CD80	941	CD80 molecule	positive regulation of signal transduction	Biological process	9915850
TRPM3	80036	transient receptor potential cation channel, subfamily M, member 3	cation transport	Biological process	15824111
CHPF2	54480	chondroitin polymerizing factor 2	chondroitin sulfate biosynthetic process	Biological process	-
PPBP	5473	pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)	extracellular space	Cellular component	-
SLC30A6	55676	solute carrier family 30 (zinc transporter), member 6	integral component of membrane	Cellular component	-
TTF2	8458	transcription termination factor, RNA polymerase II	DNA-dependent ATPase activity	Molecular function	9748214
ARL6	84100	ADP-ribosylation factor-like 6	brain development	Biological process	-
ZP3	7784	zona pellucida glycoprotein 3 (sperm receptor)	positive regulation of inflammatory response	Biological process	-
SIRT1	23411	sirtuin 1	metal ion binding	Molecular function	-
CDK5RAP3	80279	CDK5 regulatory subunit associated protein 3	positive regulation of protein ubiquitination	Biological process	16173922
ABT1	29777	activator of basal transcription 1	nucleus	Cellular component	10648625
PTGS2	5743	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	regulation of blood pressure	Biological process	-
PCDH17	27253	protocadherin 17	integral component of membrane	Cellular component	-
DPYD	1806	dihydropyrimidine dehydrogenase	NADP binding	Molecular function	-
ZNF487	642819	zinc finger protein 487	DNA binding	Molecular function	-
SLC24A2	25769	solute carrier family 24 (sodium/potassium/calcium exchanger), member 2	sodium ion transmembrane transport	Biological process	-
TAOK3	51347	TAO kinase 3	protein binding	Molecular function	11278723
CCDC130	81576	coiled-coil domain containing 130	response to virus	Biological process	3203696
FBLN2	2199	fibulin 2	extracellular exosome	Cellular component	23376485
MPC2	25874	mitochondrial pyruvate carrier 2	pyruvate metabolic process	Biological process	-
STAT5B	6777	signal transducer and activator of transcription 5B	T cell homeostasis	Biological process	-
HLA-G	3135	major histocompatibility complex, class I, G	peptide antigen binding	Molecular function	-
OR4F3	26683	olfactory receptor, family 4, subfamily F, member 3	detection of chemical stimulus involved in sensory perception	Biological process	-
ASPH	444	aspartate beta-hydroxylase	face morphogenesis	Biological process	-
SDHAF4	135154	succinate dehydrogenase complex assembly factor 4	mitochondrial matrix	Cellular component	-
SALL4	57167	spalt-like transcription factor 4	somatic stem cell maintenance	Biological process	-
PEF1	553115	penta-EF-hand domain containing 1	cytoplasm	Cellular component	11278427
ATOH7	220202	atonal homolog 7 (Drosophila)	nucleus	Cellular component	-
MAN2B1	4125	mannosidase, alpha, class 2B, member 1	lysosome	Cellular component	-
RAPGEFL1	51195	Rap guanine nucleotide exchange factor (GEF)-like 1	guanyl-nucleotide exchange factor activity	Molecular function	-
TERT	7015	telomerase reverse transcriptase	PML body	Cellular component	19567472
OR10H4	126541	olfactory receptor, family 10, subfamily H, member 4	molecular_function	Molecular function	-
EGFR	1956	epidermal growth factor receptor	negative regulation of apoptotic process	Biological process	18070883
ANXA9	8416	annexin A9	acetylcholine receptor activity	Molecular function	10899159
DNAH2	146754	dynein, axonemal, heavy chain 2	ATP binding	Molecular function	-
CALCA	796	calcitonin-related polypeptide alpha	extracellular region	Cellular component	-
GTF2E2	2961	general transcription factor IIE, polypeptide 2, beta 34kDa	poly(A) RNA binding	Molecular function	22658674
DHX30	22907	DEAH (Asp-Glu-Ala-His) box helicase 30	chromatin binding	Molecular function	18063578
SUV39H1	6839	suppressor of variegation 3-9 homolog 1 (Drosophila)	chromosome, centromeric region	Cellular component	-
ERMAP	114625	erythroblast membrane-associated protein (Scianna blood group)	integral component of membrane	Cellular component	-
MT1M	4499	metallothionein 1M	cytoplasm	Cellular component	-
SH3PXD2A	9644	SH3 and PX domains 2A	superoxide metabolic process	Biological process	20609497
PHKB	5257	phosphorylase kinase, beta	small molecule metabolic process	Biological process	-
MTOR	2475	mechanistic target of rapamycin (serine/threonine kinase)	protein autophosphorylation	Biological process	15467718
SSTR1	6751	somatostatin receptor 1	cytoplasm	Cellular component	-
EGR1	1958	early growth response 1	sequence-specific DNA binding	Molecular function	1662794
OR10A6	390093	olfactory receptor, family 10, subfamily A, member 6 (gene/pseudogene)	sensory perception of smell	Biological process	-
PROZ	8858	protein Z, vitamin K-dependent plasma glycoprotein	proteolysis	Biological process	-
G0S2	50486	G0/G1 switch 2	molecular_function	Molecular function	-
RANBP2	5903	RAN binding protein 2	negative regulation of glucokinase activity	Biological process	-
CC2D1B	200014	coiled-coil and C2 domain containing 1B	nucleus	Cellular component	-
RPS6KA4	8986	ribosomal protein S6 kinase, 90kDa, polypeptide 4	positive regulation of transcription from RNA polymerase II promoter	Biological process	20018936
GRIN2B	2904	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	regulation of excitatory postsynaptic membrane potential	Biological process	-
UBE2M	9040	ubiquitin-conjugating enzyme E2M	protein neddylation	Biological process	-
MAPKAPK5	8550	mitogen-activated protein kinase-activated protein kinase 5	stress-induced premature senescence	Biological process	17254968
SDHB	6390	succinate dehydrogenase complex, subunit B, iron sulfur (Ip)	extracellular exosome	Cellular component	23376485
AAAS	8086	achalasia, adrenocortical insufficiency, alacrimia	nuclear membrane	Cellular component	-
PHYHIPL	84457	phytanoyl-CoA 2-hydroxylase interacting protein-like	cytoplasm	Cellular component	-
TARBP2	6895	TAR (HIV-1) RNA binding protein 2	miRNA binding	Molecular function	-
KCNIP2	30819	Kv channel interacting protein 2	potassium ion export	Biological process	21493962
PIK3CA	5290	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	plasma membrane	Cellular component	-
SDC1	6382	syndecan 1	positive regulation of extracellular exosome assembly	Biological process	22660413
GFI1	2672	growth factor independent 1 transcription repressor	transcription, DNA-templated	Biological process	-
TCF12	6938	transcription factor 12	transcription factor binding	Molecular function	21828274
CYB5R1	51706	cytochrome b5 reductase 1	biological_process	Biological process	-
EDN1	1906	endothelin 1	extracellular region	Cellular component	-
HAP1	9001	huntingtin-associated protein 1	vesicle transport along microtubule	Biological process	-
ABCA6	23460	ATP-binding cassette, sub-family A (ABC1), member 6	lipid transport	Biological process	-
NBL1	4681	neuroblastoma 1, DAN family BMP antagonist	BMP binding	Molecular function	-
PIK3C3	5289	phosphatidylinositol 3-kinase, catalytic subunit type 3	toll-like receptor signaling pathway	Biological process	-
PDE3B	5140	phosphodiesterase 3B, cGMP-inhibited	angiogenesis	Biological process	-
VPS4A	27183	vacuolar protein sorting 4 homolog A (S. cerevisiae)	mitotic metaphase plate congression	Biological process	20616062
TMEM38A	79041	transmembrane protein 38A	potassium ion transmembrane transport	Biological process	-
RPN1	6184	ribophorin I	gene expression	Biological process	-
LGALS1	3956	lectin, galactoside-binding, soluble, 1	signal transduction	Biological process	12761501
HIST3H3	8290	histone cluster 3, H3	extracellular exosome	Cellular component	20458337
KCNN4	3783	potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4	apical plasma membrane	Cellular component	-
MMP9	4318	matrix metallopeptidase 9	metallopeptidase activity	Molecular function	24236012
CAV1	857	caveolin 1, caveolae protein, 22kDa	cell cortex	Cellular component	-
SGK2	10110	serum/glucocorticoid regulated kinase 2	response to oxidative stress	Biological process	10548550
C2CD4D	100191040	C2 calcium-dependent domain containing 4D	clathrin binding	Molecular function	-
IGFBP5	3488	insulin-like growth factor binding protein 5	type B pancreatic cell proliferation	Biological process	-
DSN1	79980	DSN1, MIS12 kinetochore complex component	small GTPase mediated signal transduction	Biological process	-
NF1	4763	neurofibromin 1	Ras protein signal transduction	Biological process	-
ELP4	26610	elongator acetyltransferase complex subunit 4	regulation of transcription from RNA polymerase II promoter	Biological process	11714725
FBXL7	23194	F-box and leucine-rich repeat protein 7	SCF ubiquitin ligase complex	Cellular component	-
DLG4	1742	discs, large homolog 4 (Drosophila)	cytoplasm	Cellular component	-
STX11	8676	syntaxin 11	SNARE complex	Cellular component	-
USP39	10713	ubiquitin specific peptidase 39	zinc ion binding	Molecular function	-
RAB13	5872	RAB13, member RAS oncogene family	trans-Golgi network	Cellular component	18779367
NDUFAF2	91942	NADH dehydrogenase (ubiquinone) complex I, assembly factor 2	reactive oxygen species metabolic process	Biological process	-
GNA12	2768	guanine nucleotide binding protein (G protein) alpha 12	blood coagulation	Biological process	-
PLXNB2	23654	plexin B2	integral component of plasma membrane	Cellular component	-
SMNDC1	10285	survival motor neuron domain containing 1	Cajal body	Cellular component	-
ZNF639	51193	zinc finger protein 639	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	20484494
IL4	3565	interleukin 4	response to ethanol	Biological process	-
ZNF212	7988	zinc finger protein 212	DNA binding	Molecular function	-
LRP8	7804	low density lipoprotein receptor-related protein 8, apolipoprotein e receptor	integral component of membrane	Cellular component	11152697
UGT3A1	133688	UDP glycosyltransferase 3 family, polypeptide A1	glucuronosyltransferase activity	Molecular function	22621930
PDE6C	5146	phosphodiesterase 6C, cGMP-specific, cone, alpha prime	metabolic process	Biological process	-
MACF1	23499	microtubule-actin crosslinking factor 1	positive regulation of axon extension	Biological process	22705394
SLC22A18	5002	solute carrier family 22, member 18	symporter activity	Molecular function	-
SQSTM1	8878	sequestosome 1	cell differentiation	Biological process	-
ATF2	1386	activating transcription factor 2	protein kinase binding	Molecular function	21098032
ACLY	47	ATP citrate lyase	ATP binding	Molecular function	-
TTC9B	148014	tetratricopeptide repeat domain 9B	endoplasmic reticulum membrane	Cellular component	-
PDGFA	5154	platelet-derived growth factor alpha polypeptide	cell activation	Biological process	10508235
LGR5	8549	leucine-rich repeat containing G protein-coupled receptor 5	G-protein coupled receptor activity	Molecular function	21693646
PDE3B	5140	phosphodiesterase 3B, cGMP-inhibited	cGMP-inhibited cyclic-nucleotide phosphodiesterase activity	Molecular function	8884271
MAP3K5	4217	mitogen-activated protein kinase kinase kinase 5	viral process	Biological process	-
GABRG2	2566	gamma-aminobutyric acid (GABA) A receptor, gamma 2	plasma membrane	Cellular component	-
HRAS	3265	Harvey rat sarcoma viral oncogene homolog	regulation of long-term neuronal synaptic plasticity	Biological process	-
RAD51AP1	10635	RAD51 associated protein 1	double-stranded DNA binding	Molecular function	9396801
PNN	5411	pinin, desmosome associated protein	regulation of transcription, DNA-templated	Biological process	-
NOS2	4843	nitric oxide synthase 2, inducible	regulation of insulin secretion	Biological process	8383325
OR1L4	254973	olfactory receptor, family 1, subfamily L, member 4	detection of chemical stimulus involved in sensory perception	Biological process	-
IFNA21	3452	interferon, alpha 21	natural killer cell activation involved in immune response	Biological process	-
TAC1	6863	tachykinin, precursor 1	positive regulation of renal sodium excretion	Biological process	-
KIF3B	9371	kinesin family member 3B	ATP-dependent microtubule motor activity, plus-end-directed	Molecular function	7559760
CYP26B1	56603	cytochrome P450, family 26, subfamily B, polypeptide 1	cytoplasm	Cellular component	22899867
NSG1	27065	neuron specific gene family member 1	nucleus	Cellular component	9013775
SNCA	6622	synuclein, alpha (non A4 component of amyloid precursor)	positive regulation of receptor recycling	Biological process	18980610
EGR4	1961	early growth response 4	sequence-specific DNA binding transcription factor activity	Molecular function	-
CHGA	1113	chromogranin A	defense response to Gram-negative bacterium	Biological process	15723172
ARPC5	10092	actin related protein 2/3 complex, subunit 5, 16kDa	actin cytoskeleton organization	Biological process	9359840
CENPV	201161	centromere protein V	nucleoplasm	Cellular component	-
OR7G1	125962	olfactory receptor, family 7, subfamily G, member 1	G-protein coupled receptor signaling pathway	Biological process	-
TNFSF9	8744	tumor necrosis factor (ligand) superfamily, member 9	positive regulation of interleukin-6 production	Biological process	-
CRAT	1384	carnitine O-acetyltransferase	receptor binding	Molecular function	20178365
MYH10	4628	myosin, heavy chain 10, non-muscle	cleavage furrow	Cellular component	11029059
GDPGP1	390637	GDP-D-glucose phosphorylase 1	GDP-D-glucose phosphorylase activity	Molecular function	21507950
LAMA1	284217	laminin, alpha 1	extracellular matrix organization	Biological process	-
AGRP	181	agouti related neuropeptide	extracellular space	Cellular component	15927146
TNS4	84951	tensin 4	apoptotic process	Biological process	-
EPHX2	2053	epoxide hydrolase 2, cytoplasmic	xenobiotic metabolic process	Biological process	10862610
ZNF195	7748	zinc finger protein 195	nucleus	Cellular component	-
AKR1C4	1109	aldo-keto reductase family 1, member C4	phototransduction, visible light	Biological process	-
RFC1	5981	replication factor C (activator 1) 1, 145kDa	DNA-dependent DNA replication	Biological process	8248204
IGHMBP2	3508	immunoglobulin mu binding protein 2	protein binding	Molecular function	19299493
TICAM2	353376	toll-like receptor adaptor molecule 2	I-kappaB kinase/NF-kappaB signaling	Biological process	-
SETMAR	6419	SET domain and mariner transposase fusion gene	transposase activity	Molecular function	-
DNAJC10	54431	DnaJ (Hsp40) homolog, subfamily C, member 10	cell redox homeostasis	Biological process	-
ASPSCR1	79058	alveolar soft part sarcoma chromosome region, candidate 1	molecular_function	Molecular function	-
PSENEN	55851	presenilin enhancer gamma secretase subunit	axon guidance	Biological process	-
KPNB1	3837	karyopherin (importin) beta 1	viral process	Biological process	-
LRRC10	376132	leucine rich repeat containing 10	mitochondrion	Cellular component	-
CUL4B	8450	cullin 4B	translesion synthesis	Biological process	-
CCBE1	147372	collagen and calcium binding EGF domains 1	positive regulation of endothelial cell migration	Biological process	-
SOAT1	6646	sterol O-acyltransferase 1	fatty-acyl-CoA binding	Molecular function	16647063
INCA1	388324	inhibitor of CDK, cyclin A1 interacting protein 1	nucleus	Cellular component	-
GLRX	2745	glutaredoxin (thioltransferase)	nucleobase-containing small molecule interconversion	Biological process	-
XPNPEP3	63929	X-prolyl aminopeptidase 3, mitochondrial	mitochondrion	Cellular component	20179356
SMARCD1	6602	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	chromatin remodeling	Biological process	12917342
B3GNT4	79369	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4	post-translational protein modification	Biological process	-
BAG6	7917	BCL2-associated athanogene 6	cell differentiation	Biological process	-
DDX5	1655	DEAD (Asp-Glu-Ala-Asp) box helicase 5	positive regulation of intracellular estrogen receptor signaling pathway	Biological process	-
ASCL2	430	achaete-scute family bHLH transcription factor 2	transcription, DNA-templated	Biological process	14561729
ZP3	7784	zona pellucida glycoprotein 3 (sperm receptor)	positive regulation of protein kinase activity	Biological process	18667750
NR5A2	2494	nuclear receptor subfamily 5, group A, member 2	protein binding	Molecular function	12040021
SH2B1	25970	SH2B adaptor protein 1	blood coagulation	Biological process	-
PPIL4	85313	peptidylprolyl isomerase (cyclophilin)-like 4	regulation of phosphorylation of RNA polymerase II C-terminal domain	Biological process	-
ITGA7	3679	integrin, alpha 7	muscle tendon junction	Cellular component	-
EZR	7430	ezrin	microspike	Cellular component	-
BSND	7809	barttin CLCNK-type chloride channel accessory beta subunit	chloride transmembrane transport	Biological process	-
TRPM7	54822	transient receptor potential cation channel, subfamily M, member 7	ion transmembrane transport	Biological process	-
TPR	7175	translocated promoter region, nuclear basket protein	protein sumoylation	Biological process	-
ONECUT1	3175	one cut homeobox 1	endocrine pancreas development	Biological process	-
AJUBA	84962	ajuba LIM protein	protein binding	Molecular function	15778465
CDK5R1	8851	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	neuron cell-cell adhesion	Biological process	-
ANXA4	307	annexin A4	plasma membrane	Cellular component	16687573
CNOT2	4848	CCR4-NOT transcription complex, subunit 2	membrane	Cellular component	19946888
ANK1	286	ankyrin 1, erythrocytic	postsynaptic membrane	Cellular component	-
OR13C4	138804	olfactory receptor, family 13, subfamily C, member 4	sensory perception of smell	Biological process	-
PTGS2	5743	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	positive regulation of vascular endothelial growth factor production	Biological process	9630216
ADRA2A	150	adrenoceptor alpha 2A	protein kinase binding	Molecular function	15653687
S1PR1	1901	sphingosine-1-phosphate receptor 1	positive regulation of cell migration	Biological process	-
ADGRB1	575	adhesion G protein-coupled receptor B1	integral component of plasma membrane	Cellular component	9647739
CENPN	55839	centromere protein N	nucleosome assembly	Biological process	-
TERT	7015	telomerase reverse transcriptase	DNA biosynthetic process	Biological process	19701182
ABCC12	94160	ATP-binding cassette, sub-family C (CFTR/MRP), member 12	integral component of membrane	Cellular component	-
TM2D1	83941	TM2 domain containing 1	beta-amyloid binding	Molecular function	-
CAMK2D	817	calcium/calmodulin-dependent protein kinase II delta	positive regulation of smooth muscle cell migration	Biological process	-
TLE3	7090	transducin-like enhancer of split 3	Notch signaling pathway	Biological process	-
MPP4	58538	membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)	nucleoplasm	Cellular component	-
UBA52	7311	ubiquitin A-52 residue ribosomal protein fusion product 1	programmed necrotic cell death	Biological process	-
Sep-02	4735	septin 2	midbody	Cellular component	-
PFN2	5217	profilin 2	protein stabilization	Biological process	18573880
DDX11	1663	DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11	nucleus	Cellular component	17189189
MAP3K1	4214	mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase	regulation of cell migration	Biological process	-
FNIP1	96459	folliculin interacting protein 1	cellular response to starvation	Biological process	-
MPZL1	9019	myelin protein zero-like 1	protein binding	Molecular function	10681522
TBC1D10A	83874	TBC1 domain family, member 10A	activation of cysteine-type endopeptidase activity	Biological process	18387192
SPAG5	10615	sperm associated antigen 5	chromosome segregation	Biological process	21402792
C14orf169	79697	chromosome 14 open reading frame 169	transcription, DNA-templated	Biological process	-
UFD1L	7353	ubiquitin fusion degradation 1 like (yeast)	VCP-NPL4-UFD1 AAA ATPase complex	Cellular component	-
RLTPR	146206	RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing	positive regulation of interleukin-2 secretion	Biological process	-
SFTPA1	653509	surfactant protein A1	carbohydrate binding	Molecular function	-
PIK3CG	5294	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	inflammatory response	Biological process	17290298
PSMA5	5686	proteasome (prosome, macropain) subunit, alpha type, 5	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition	Biological process	-
SKP2	6502	S-phase kinase-associated protein 2, E3 ubiquitin protein ligase	nucleolus	Cellular component	-
SLFN11	91607	schlafen family member 11	tRNA binding	Molecular function	23000900
CEP290	80184	centrosomal protein 290kDa	cilium morphogenesis	Biological process	-
SOD1	6647	superoxide dismutase 1, soluble	extracellular exosome	Cellular component	19056867
GNB3	2784	guanine nucleotide binding protein (G protein), beta polypeptide 3	protein binding	Molecular function	23773523
KIN	22944	Kin17 DNA and RNA binding protein	DNA replication	Biological process	12359749
CCNB1	891	cyclin B1	histone H3-S10 phosphorylation involved in chromosome condensation	Biological process	-
PDPK1	5170	3-phosphoinositide dependent protein kinase 1	negative regulation of cardiac muscle cell apoptotic process	Biological process	-
DDX60	55601	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	cytoplasm	Cellular component	-
PRPF4	9128	pre-mRNA processing factor 4	U4/U6 snRNP	Cellular component	9570313
APOBEC1	339	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	protein binding	Molecular function	10669759
RDH11	51109	retinol dehydrogenase 11 (all-trans/9-cis/11-cis)	retinal metabolic process	Biological process	12807874
AKR1B10	57016	aldo-keto reductase family 1, member B10 (aldose reductase)	cellular aldehyde metabolic process	Biological process	9565553
NFAM1	150372	NFAT activating protein with ITAM motif 1	signal transduction	Biological process	12615919
COL2A1	1280	collagen, type II, alpha 1	cartilage condensation	Biological process	-
MYBL1	4603	v-myb avian myeloblastosis viral oncogene homolog-like 1	positive regulation of transcription, DNA-templated	Biological process	8058310
DLG5	9231	discs, large homolog 5 (Drosophila)	epithelial tube branching involved in lung morphogenesis	Biological process	-
SCYL3	57147	SCY1-like 3 (S. cerevisiae)	lamellipodium	Cellular component	12651155
NDUFA10	4705	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa	cellular metabolic process	Biological process	-
FGD4	121512	FYVE, RhoGEF and PH domain containing 4	filopodium assembly	Biological process	-
SLC24A5	283652	solute carrier family 24 (sodium/potassium/calcium exchanger), member 5	melanosome	Cellular component	-
MAGI2	9863	membrane associated guanylate kinase, WW and PDZ domain containing 2	late endosome	Cellular component	-
PRIM2	5558	primase, DNA, polypeptide 2 (58kDa)	DNA replication, synthesis of RNA primer	Biological process	-
FGFR2	2263	fibroblast growth factor receptor 2	protein autophosphorylation	Biological process	15629145
SMEK1	55671	SMEK homolog 1, suppressor of mek1 (Dictyostelium)	cytoplasm	Cellular component	-
IL36A	27179	interleukin 36, alpha	cytokine-mediated signaling pathway	Biological process	-
AGL	178	amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase	glucose metabolic process	Biological process	-
EIF2B3	8891	eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa	cellular response to stimulus	Biological process	8626696
ADORA2A	135	adenosine A2a receptor	positive regulation of apoptotic signaling pathway	Biological process	-
FABP9	646480	fatty acid binding protein 9, testis	small molecule metabolic process	Biological process	-
ARF5	381	ADP-ribosylation factor 5	vesicle-mediated transport	Biological process	-
GSN	2934	gelsolin	protein domain specific binding	Molecular function	23729654
NUP88	4927	nucleoporin 88kDa	hexose transport	Biological process	-
CYB5R3	1727	cytochrome b5 reductase 3	vitamin metabolic process	Biological process	-
SMG1	23049	SMG1 phosphatidylinositol 3-kinase-related kinase	mRNA export from nucleus	Biological process	16488880
MITF	4286	microphthalmia-associated transcription factor	regulation of cell proliferation	Biological process	-
RNF14	9604	ring finger protein 14	regulation of transcription, DNA-templated	Biological process	19345326
PTPN12	5782	protein tyrosine phosphatase, non-receptor type 12	SH3 domain binding	Molecular function	9285683
HTT	3064	huntingtin	neural plate formation	Biological process	-
CBL	867	Cbl proto-oncogene, E3 ubiquitin protein ligase	nucleus	Cellular component	-
PCDHB8	56128	protocadherin beta 8	plasma membrane	Cellular component	-
CACNA1D	776	calcium channel, voltage-dependent, L type, alpha 1D subunit	high voltage-gated calcium channel activity	Molecular function	1309651
DMTN	2039	dematin actin binding protein	positive regulation of fibroblast migration	Biological process	-
POLR2A	5430	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	transcription-coupled nucleotide-excision repair	Biological process	-
CD36	948	CD36 molecule (thrombospondin receptor)	toll-like receptor signaling pathway	Biological process	-
HSPD1	3329	heat shock 60kDa protein 1 (chaperonin)	plasma membrane	Cellular component	-
BBS4	585	Bardet-Biedl syndrome 4	ciliary transition zone	Cellular component	23943788
SERPINB13	5275	serpin peptidase inhibitor, clade B (ovalbumin), member 13	cytoplasm	Cellular component	12809493
EDNRA	1909	endothelin receptor type A	neural crest cell development	Biological process	-
RASD1	51655	RAS, dexamethasone-induced 1	GTP binding	Molecular function	-
XCL1	6375	chemokine (C motif) ligand 1	positive regulation of T-helper 1 cell cytokine production	Biological process	-
RTCB	51493	RNA 2',3'-cyclic phosphate and 5'-OH ligase	tRNA-splicing ligase complex	Cellular component	21311021
MSRB1	51734	methionine sulfoxide reductase B1	actin cytoskeleton	Cellular component	-
INPP5B	3633	inositol polyphosphate-5-phosphatase, 75kDa	cytoplasm	Cellular component	-
RTN3	10313	reticulon 3	apoptotic process	Biological process	-
TRIB3	57761	tribbles pseudokinase 3	innate immune response	Biological process	-
TM9SF1	10548	transmembrane 9 superfamily member 1	lysosomal membrane	Cellular component	-
CRP	1401	C-reactive protein, pentraxin-related	virion binding	Molecular function	23544079
ZNF235	9310	zinc finger protein 235	metal ion binding	Molecular function	-
EIF2B3	8891	eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa	translational initiation	Biological process	-
DYX1C1	161582	dyslexia susceptibility 1 candidate 1	neuron migration	Biological process	-
DNAH10	196385	dynein, axonemal, heavy chain 10	microtubule motor activity	Molecular function	-
CCT6A	908	chaperonin containing TCP1, subunit 6A (zeta 1)	cytoplasm	Cellular component	8034610
ANO4	121601	anoctamin 4	calcium activated phosphatidylserine scrambling	Biological process	-
CITED1	4435	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1	negative regulation of Wnt signaling pathway	Biological process	17336183
SH3BP4	23677	SH3-domain binding protein 4	negative regulation of GTPase activity	Biological process	22575674
PCNA	5111	proliferating cell nuclear antigen	MutLalpha complex binding	Molecular function	11005803
RAD52	5893	RAD52 homolog (S. cerevisiae)	DNA recombination	Biological process	8702565
ITFG2	55846	integrin alpha FG-GAP repeat containing 2	cytosol	Cellular component	-
ZNF763	284390	zinc finger protein 763	transcription cofactor activity	Molecular function	-
IGF1R	3480	insulin-like growth factor 1 receptor	neuron projection	Cellular component	-
SCAI	286205	suppressor of cancer cell invasion	negative regulation of cell migration	Biological process	19350017
D2HGDH	728294	D-2-hydroxyglutarate dehydrogenase	cellular protein metabolic process	Biological process	15070399
LDOC1	23641	leucine zipper, down-regulated in cancer 1	negative regulation of cell proliferation	Biological process	-
EPC2	26122	enhancer of polycomb homolog 2 (Drosophila)	chromatin modification	Biological process	-
DLGAP1	9229	discs, large (Drosophila) homolog-associated protein 1	cellular_component	Cellular component	-
ASCL1	429	achaete-scute family bHLH transcription factor 1	noradrenergic neuron development	Biological process	-
AQP2	359	aquaporin 2 (collecting duct)	PDZ domain binding	Molecular function	-
RSAD1	55316	radical S-adenosyl methionine domain containing 1	oxidation-reduction process	Biological process	-
RUNX2	860	runt-related transcription factor 2	positive regulation of transcription, DNA-templated	Biological process	11965546
SLC2A2	6514	solute carrier family 2 (facilitated glucose transporter), member 2	glucose import	Biological process	-
RHOB	388	ras homolog family member B	Rho protein signal transduction	Biological process	3888408
DDAH1	23576	dimethylarginine dimethylaminohydrolase 1	positive regulation of angiogenesis	Biological process	-
SLC36A2	153201	solute carrier family 36 (proton/amino acid symporter), member 2	proton transport	Biological process	-
NAPB	63908	N-ethylmaleimide-sensitive factor attachment protein, beta	soluble NSF attachment protein activity	Molecular function	-
OR2H2	7932	olfactory receptor, family 2, subfamily H, member 2	sensory perception of smell	Biological process	-
TXNDC5	81567	thioredoxin domain containing 5 (endoplasmic reticulum)	post-Golgi vesicle-mediated transport	Biological process	-
SLC9A3R1	9368	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1	phosphatase binding	Molecular function	16456542
B4GALNT1	2583	beta-1,4-N-acetyl-galactosaminyl transferase 1	membrane	Cellular component	1601877
ADCY2	108	adenylate cyclase 2 (brain)	adenylate cyclase activity	Molecular function	1427768
SESTD1	91404	SEC14 and spectrin domains 1	phosphatidylinositol-3-phosphate binding	Molecular function	20164195
ALOX15B	247	arachidonate 15-lipoxygenase, type B	cytoplasm	Cellular component	-
GALNS	2588	galactosamine (N-acetyl)-6-sulfatase	extracellular exosome	Cellular component	23376485
C3orf20	84077	chromosome 3 open reading frame 20	cytoplasm	Cellular component	-
NOL7	51406	nucleolar protein 7, 27kDa	nucleus	Cellular component	-
GIP	2695	gastric inhibitory polypeptide	response to peptide hormone	Biological process	-
SAC3D1	29901	SAC3 domain containing 1	spindle	Cellular component	-
PARM1	25849	prostate androgen-regulated mucin-like protein 1	early endosome	Cellular component	18027867
MMP26	56547	matrix metallopeptidase 26	negative regulation of inflammatory response	Biological process	23569462
PPP2CA	5515	protein phosphatase 2, catalytic subunit, alpha isozyme	microtubule cytoskeleton	Cellular component	11007961
HIST2H3D	653604	histone cluster 2, H3d	negative regulation of gene expression, epigenetic	Biological process	-
SLC1A6	6511	solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6	L-glutamate transmembrane transport	Biological process	-
GAL3ST2	64090	galactose-3-O-sulfotransferase 2	integral component of membrane	Cellular component	-
RAB22A	57403	RAB22A, member RAS oncogene family	phagocytic vesicle membrane	Cellular component	-
NMNAT3	349565	nicotinamide nucleotide adenylyltransferase 3	vitamin metabolic process	Biological process	-
LRRC46	90506	leucine rich repeat containing 46	regulation of protein stability	Biological process	24270810
ADM	133	adrenomedullin	cytosol	Cellular component	-
NLGN1	22871	neuroligin 1	cytoskeletal matrix organization at active zone	Biological process	-
MEN1	4221	multiple endocrine neoplasia I	negative regulation of sequence-specific DNA binding transcription factor activity	Biological process	11526476
ITPR3	3710	inositol 1,4,5-trisphosphate receptor, type 3	cytosol	Cellular component	-
KCNA2	3737	potassium channel, voltage gated shaker related subfamily A, member 2	juxtaparanode region of axon	Cellular component	-
NFU1	27247	NFU1 iron-sulfur cluster scaffold	mitochondrion	Cellular component	12886008
GNAT1	2779	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1	apical plasma membrane	Cellular component	-
GEN1	348654	GEN1 Holliday junction 5' flap endonuclease	centrosome	Cellular component	23166748
OGG1	4968	8-oxoguanine DNA glycosylase	protein complex	Cellular component	19506022
LEF1	51176	lymphoid enhancer-binding factor 1	forebrain neuron differentiation	Biological process	-
ADORA1	134	adenosine A1 receptor	basolateral plasma membrane	Cellular component	-
ATPIF1	93974	ATPase inhibitory factor 1	angiostatin binding	Molecular function	15528193
CNIH4	29097	cornichon family AMPA receptor auxiliary protein 4	ER to Golgi vesicle-mediated transport	Biological process	24405750
NPAS3	64067	neuronal PAS domain protein 3	protein dimerization activity	Molecular function	-
MYO9B	4650	myosin IXB	actin cytoskeleton	Cellular component	8907710
MC5R	4161	melanocortin 5 receptor	melanocortin receptor activity	Molecular function	-
AKIRIN2	55122	akirin 2	positive regulation of endopeptidase activity	Biological process	-
ILDR2	387597	immunoglobulin-like domain containing receptor 2	response to glucose	Biological process	-
ARNTL2	56938	aryl hydrocarbon receptor nuclear translocator-like 2	transcription from RNA polymerase II promoter	Biological process	15147242
IGF2R	3482	insulin-like growth factor 2 receptor	perinuclear region of cytoplasm	Cellular component	-
ERAP1	51752	endoplasmic reticulum aminopeptidase 1	response to bacterium	Biological process	16034137
EDN1	1906	endothelin 1	basal part of cell	Cellular component	-
ACSS2	55902	acyl-CoA synthetase short-chain family member 2	intracellular membrane-bounded organelle	Cellular component	-
APPL1	26060	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	NuRD complex	Cellular component	15016378
CETN1	1068	centrin, EF-hand protein, 1	spindle pole	Cellular component	8175926
NFIX	4784	nuclear factor I/X (CCAAT-binding transcription factor)	cerebellar granule cell differentiation	Biological process	-
EIF3A	8661	eukaryotic translation initiation factor 3, subunit A	nucleolus	Cellular component	-
GSTM1	2944	glutathione S-transferase mu 1	glutathione binding	Molecular function	8373352
PCLO	27445	piccolo presynaptic cytomatrix protein	calcium-dependent phospholipid binding	Molecular function	-
CUL1	8454	cullin 1	ubiquitin protein ligase binding	Molecular function	-
PDGFRA	5156	platelet-derived growth factor receptor, alpha polypeptide	positive regulation of phosphatidylinositol 3-kinase activity	Biological process	1646396
APEX1	328	APEX nuclease (multifunctional DNA repair enzyme) 1	mitotic cell cycle	Biological process	-
AMOTL2	51421	angiomotin like 2	hippo signaling	Biological process	-
TIE1	7075	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	angiogenesis	Biological process	-
DEFB104B	503618	defensin, beta 104B	defense response to bacterium	Biological process	-
GAS2L2	246176	growth arrest-specific 2 like 2	negative regulation of microtubule depolymerization	Biological process	12584248
CAV2	858	caveolin 2	negative regulation of endothelial cell proliferation	Biological process	-
TAF1C	9013	TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa	transcription from RNA polymerase II promoter	Biological process	7801123
RABGEF1	27342	RAB guanine nucleotide exchange factor (GEF) 1	vesicle	Cellular component	-
GNAS	2778	GNAS complex locus	embryonic cranial skeleton morphogenesis	Biological process	-
DNAAF1	123872	dynein, axonemal, assembly factor 1	plasma membrane	Cellular component	-
B4GALT3	8703	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3	protein N-linked glycosylation via asparagine	Biological process	-
NOTCH1	4851	notch 1	hair follicle morphogenesis	Biological process	-
EEF1G	1937	eukaryotic translation elongation factor 1 gamma	response to virus	Biological process	16548883
CDKN1A	1026	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	cellular response to DNA damage stimulus	Biological process	20160708
NCBP1	4686	nuclear cap binding protein subunit 1, 80kDa	mRNA cleavage	Biological process	9342333
CRK	1398	v-crk avian sarcoma virus CT10 oncogene homolog	protein binding	Molecular function	10464310
TBK1	29110	TANK-binding kinase 1	ATP binding	Molecular function	-
H2AFY	9555	H2A histone family, member Y	negative regulation of gene expression, epigenetic	Biological process	19734898
TAF4B	6875	TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa	transcription elongation from RNA polymerase II promoter	Biological process	-
PLCZ1	89869	phospholipase C, zeta 1	nucleus	Cellular component	-
NPEPPS	9520	aminopeptidase puromycin sensitive	cytosol	Cellular component	-
KRT83	3889	keratin 83, type II	hair cycle	Biological process	21916889
MN1	4330	meningioma (disrupted in balanced translocation) 1	cellular_component	Cellular component	-
DGAT1	8694	diacylglycerol O-acyltransferase 1	small molecule metabolic process	Biological process	-
PPARD	5467	peroxisome proliferator-activated receptor delta	phospholipid biosynthetic process	Biological process	-
SMAD4	4089	SMAD family member 4	epithelial to mesenchymal transition involved in endocardial cushion formation	Biological process	-
ZSCAN2	54993	zinc finger and SCAN domain containing 2	cell differentiation	Biological process	-
ZNF840P	100130863	zinc finger protein 840, pseudogene	nucleus	Cellular component	-
FSTL3	10272	follistatin-like 3 (secreted glycoprotein)	transcription, DNA-templated	Biological process	-
PRPF31	26121	pre-mRNA processing factor 31	spliceosomal tri-snRNP complex assembly	Biological process	15257298
LIN7A	8825	lin-7 homolog A (C. elegans)	synapse	Cellular component	-
ARFIP1	27236	ADP-ribosylation factor interacting protein 1	protein domain specific binding	Molecular function	-
HDAC10	83933	histone deacetylase 10	negative regulation of transcription from RNA polymerase II promoter	Biological process	11726666
SAFB2	9667	scaffold attachment factor B2	poly(A) RNA binding	Molecular function	22658674
SLC1A2	6506	solute carrier family 1 (glial high affinity glutamate transporter), member 2	ion transport	Biological process	-
STX19	415117	syntaxin 19	protein binding	Molecular function	23455924
NDC80	10403	NDC80 kinetochore complex component	small GTPase mediated signal transduction	Biological process	-
ASIC2	40	acid sensing (proton gated) ion channel 2	regulation of gene expression	Biological process	21810271
RIMS1	22999	regulating synaptic membrane exocytosis 1	regulation of long-term neuronal synaptic plasticity	Biological process	-
CLN3	1201	ceroid-lipofuscinosis, neuronal 3	negative regulation of neuron apoptotic process	Biological process	-
KCNK15	60598	potassium channel, two pore domain subfamily K, member 15	regulation of ion transmembrane transport	Biological process	-
TESK1	7016	testis-specific kinase 1	ATP binding	Molecular function	-
G3BP2	9908	GTPase activating protein (SH3 domain) binding protein 2	Ras protein signal transduction	Biological process	9575347
CD1C	911	CD1c molecule	endogenous lipid antigen binding	Molecular function	21167756
SERPINF1	5176	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1	negative regulation of gene expression	Biological process	-
NAP1L5	266812	nucleosome assembly protein 1-like 5	nucleosome assembly	Biological process	-
PACS1	55690	phosphofurin acidic cluster sorting protein 1	COPI-coated vesicle	Cellular component	-
COX11	1353	COX11 cytochrome c oxidase copper chaperone	integral component of membrane	Cellular component	-
MRPL3	11222	mitochondrial ribosomal protein L3	mitochondrial inner membrane	Cellular component	-
OR5B2	390190	olfactory receptor, family 5, subfamily B, member 2	olfactory receptor activity	Molecular function	-
UBE3A	7337	ubiquitin protein ligase E3A	proteolysis	Biological process	8221889
HIST1H3B	8358	histone cluster 1, H3b	nucleosome assembly	Biological process	25615412
MTRR	4552	5-methyltetrahydrofolate-homocysteine methyltransferase reductase	iron ion binding	Molecular function	-
SAP30L	79685	SAP30-like	regulation of transcription, DNA-templated	Biological process	-
YWHAG	7532	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma	programmed cell death	Biological process	-
NPC1L1	29881	NPC1-like 1	cholesterol biosynthetic process	Biological process	17140581
MYH10	4628	myosin, heavy chain 10, non-muscle	ATP binding	Molecular function	7782316
SENP1	29843	SUMO1/sentrin specific peptidase 1	cytoplasm	Cellular component	-
PLA2G4F	255189	phospholipase A2, group IVF	ruffle membrane	Cellular component	-
NFATC1	4772	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	cytoplasm	Cellular component	-
HSF4	3299	heat shock transcription factor 4	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
PHB2	11331	prohibitin 2	nucleus	Cellular component	-
KCTD13	253980	potassium channel tetramerization domain containing 13	nucleus	Cellular component	-
HIST1H3D	8351	histone cluster 1, H3d	extracellular region	Cellular component	-
ASB14	142686	ankyrin repeat and SOCS box containing 14	intracellular	Cellular component	-
ABCC4	10257	ATP-binding cassette, sub-family C (CFTR/MRP), member 4	response to organic cyclic compound	Biological process	-
CDH13	1012	cadherin 13	positive regulation of cell-matrix adhesion	Biological process	17573778
LARP6	55323	La ribonucleoprotein domain family, member 6	RNA processing	Biological process	-
PSME3	10197	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)	innate immune response	Biological process	-
CD55	1604	CD55 molecule, decay accelerating factor for complement (Cromer blood group)	positive regulation of CD4-positive, alpha-beta T cell proliferation	Biological process	16818763
MSL1	339287	male-specific lethal 1 homolog (Drosophila)	chromatin organization	Biological process	-
YWHAZ	7534	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta	perinuclear region of cytoplasm	Cellular component	-
MYH6	4624	myosin, heavy chain 6, cardiac muscle, alpha	myosin complex	Cellular component	12933792
ARHGAP29	9411	Rho GTPase activating protein 29	small GTPase mediated signal transduction	Biological process	-
RAE1	8480	ribonucleic acid export 1	cellular response to organic cyclic compound	Biological process	-
SNX2	6643	sorting nexin 2	epidermal growth factor receptor binding	Molecular function	9819414
PDK2	5164	pyruvate dehydrogenase kinase, isozyme 2	protein kinase activity	Molecular function	10748134
PANK2	80025	pantothenate kinase 2	mitochondrion morphogenesis	Biological process	-
ACVR1	90	activin A receptor, type I	embryonic heart tube morphogenesis	Biological process	19506109
ALOX12B	242	arachidonate 12-lipoxygenase, 12R type	protein binding	Molecular function	22622417
FAM86C1	55199	family with sequence similarity 86, member C1	methyltransferase activity	Molecular function	-
CPSF4	10898	cleavage and polyadenylation specific factor 4, 30kDa	viral life cycle	Biological process	-
TPR	7175	translocated promoter region, nuclear basket protein	cytoplasmic dynein complex	Cellular component	20133940
MYL12A	10627	myosin, light chain 12A, regulatory, non-sarcomeric	extracellular exosome	Cellular component	20458337
RET	5979	ret proto-oncogene	lymphocyte migration into lymphoid organs	Biological process	-
TPM1	7168	tropomyosin 1 (alpha)	filamentous actin	Cellular component	-
ERBB4	2066	erb-b2 receptor tyrosine kinase 4	positive regulation of tyrosine phosphorylation of Stat5 protein	Biological process	16837552
GALNT3	2591	polypeptide N-acetylgalactosaminyltransferase 3	post-translational protein modification	Biological process	-
TUBB4A	10382	tubulin, beta 4A class IVa	neuronal cell body	Cellular component	-
YWHAE	7531	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon	phosphoprotein binding	Molecular function	10869435
PPM1B	5495	protein phosphatase, Mg2+/Mn2+ dependent, 1B	protein binding	Molecular function	16872604
VTCN1	79679	V-set domain containing T cell activation inhibitor 1	immune system process	Biological process	-
NCOR2	9612	nuclear receptor corepressor 2	Notch signaling pathway	Biological process	-
KCNMB3	27094	potassium channel subfamily M regulatory beta subunit 3	plasma membrane	Cellular component	-
RC3H1	149041	ring finger and CCCH-type domains 1	regulation of germinal center formation	Biological process	-
SMPD4	55627	sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)	Golgi apparatus	Cellular component	16517606
TOLLIP	54472	toll interacting protein	kinase binding	Molecular function	10854325
NGEF	25791	neuronal guanine nucleotide exchange factor	Rho guanyl-nucleotide exchange factor activity	Molecular function	-
POLR2H	5437	polymerase (RNA) II (DNA directed) polypeptide H	transcription initiation from RNA polymerase I promoter	Biological process	-
CNDP1	84735	carnosine dipeptidase 1 (metallopeptidase M20 family)	metal ion binding	Molecular function	-
PRDX3	10935	peroxiredoxin 3	hydrogen peroxide catabolic process	Biological process	18195003
CDCA4	55038	cell division cycle associated 4	nucleus	Cellular component	-
GKN1	56287	gastrokine 1	positive regulation of cell division	Biological process	-
CBLN1	869	cerebellin 1 precursor	nervous system development	Biological process	1704129
C14orf169	79697	chromosome 14 open reading frame 169	histone H3-K4 demethylation	Biological process	-
NLGN1	22871	neuroligin 1	postsynaptic density	Cellular component	-
MAP3K6	9064	mitogen-activated protein kinase kinase kinase 6	ATP binding	Molecular function	9875215
IRAK2	3656	interleukin-1 receptor-associated kinase 2	positive regulation of NF-kappaB transcription factor activity	Biological process	-
RINT1	60561	RAD50 interactor 1	cell cycle	Biological process	-
PEBP1	5037	phosphatidylethanolamine binding protein 1	nucleus	Cellular component	21630459
STEAP3	55240	STEAP family member 3, metalloreductase	exosomal secretion	Biological process	-
RTN4RL1	146760	reticulon 4 receptor-like 1	extracellular exosome	Cellular component	23533145
WISP2	8839	WNT1 inducible signaling pathway protein 2	heparin binding	Molecular function	-
NBL1	4681	neuroblastoma 1, DAN family BMP antagonist	neuron projection morphogenesis	Biological process	-
TDRD9	122402	tudor domain containing 9	male meiosis	Biological process	-
ORC2	4999	origin recognition complex, subunit 2	G1/S transition of mitotic cell cycle	Biological process	-
BCAS3	54828	breast carcinoma amplified sequence 3	cell periphery	Cellular component	-
GLRA3	8001	glycine receptor, alpha 3	chloride transmembrane transport	Biological process	-
POU3F2	5454	POU class 3 homeobox 2	forebrain ventricular zone progenitor cell division	Biological process	-
UGDH	7358	UDP-glucose 6-dehydrogenase	oxidation-reduction process	Biological process	-
E4F1	1877	E4F transcription factor 1	regulation of growth	Biological process	-
PRPS2	5634	phosphoribosyl pyrophosphate synthetase 2	ADP binding	Molecular function	-
TC2N	123036	tandem C2 domains, nuclear	calcium ion binding	Molecular function	-
LHX1	3975	LIM homeobox 1	cell-cell signaling	Biological process	-
TOMM5	401505	translocase of outer mitochondrial membrane 5 homolog (yeast)	mitochondrion	Cellular component	-
ZRANB1	54764	zinc finger, RAN-binding domain containing 1	protein binding	Molecular function	11463333
FOXD3	27022	forkhead box D3	sequence-specific DNA binding transcription factor activity	Molecular function	-
ZNF282	8427	zinc finger protein 282	zinc ion binding	Molecular function	9396811
SEMA7A	8482	semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)	positive regulation of macrophage cytokine production	Biological process	-
PTPRD	5789	protein tyrosine phosphatase, receptor type, D	cell adhesion molecule binding	Molecular function	-
FBN1	2200	fibrillin 1	basement membrane	Cellular component	3536967
FANCC	2176	Fanconi anemia, complementation group C	Fanconi anaemia nuclear complex	Cellular component	20347428
TBPL2	387332	TATA box binding protein like 2	cytoplasm	Cellular component	14634207
EPB41L3	23136	erythrocyte membrane protein band 4.1-like 3	apoptotic process	Biological process	-
USP39	10713	ubiquitin specific peptidase 39	ubiquitin-dependent protein catabolic process	Biological process	-
SMC3	9126	structural maintenance of chromosomes 3	ATP binding	Molecular function	-
UBE2I	7329	ubiquitin-conjugating enzyme E2I	cellular protein modification process	Biological process	8798754
OXA1L	5018	oxidase (cytochrome c) assembly 1-like	mitochondrial respiratory chain complex I assembly	Biological process	17936786
PROKR2	128674	prokineticin receptor 2	plasma membrane	Cellular component	-
MAP3K14	9020	mitogen-activated protein kinase kinase kinase 14	NIK/NF-kappaB signaling	Biological process	-
PRKAB2	5565	protein kinase, AMP-activated, beta 2 non-catalytic subunit	small molecule metabolic process	Biological process	-
PCCB	5096	propionyl CoA carboxylase, beta polypeptide	water-soluble vitamin metabolic process	Biological process	-
AGO2	27161	argonaute RISC catalytic component 2	RNA polymerase II core binding	Molecular function	25336585
NFKBIL1	4795	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1	cytosol	Cellular component	-
HTR3B	9177	5-hydroxytryptamine (serotonin) receptor 3B, ionotropic	cation transmembrane transport	Biological process	-
CROT	54677	carnitine O-octanoyltransferase	peroxisome	Cellular component	10486279
OR5AR1	219493	olfactory receptor, family 5, subfamily AR, member 1 (gene/pseudogene)	plasma membrane	Cellular component	-
KDM4B	23030	lysine (K)-specific demethylase 4B	focal adhesion	Cellular component	-
HLA-DRB5	3127	major histocompatibility complex, class II, DR beta 5	plasma membrane	Cellular component	-
PPP1R1B	84152	protein phosphatase 1, regulatory (inhibitor) subunit 1B	cytosol	Cellular component	-
RPLP1	6176	ribosomal protein, large, P1	viral life cycle	Biological process	-
CDHR3	222256	cadherin-related family member 3	calcium ion binding	Molecular function	-
OIP5	11339	Opa interacting protein 5	CENP-A containing nucleosome assembly	Biological process	-
ERN2	10595	endoplasmic reticulum to nucleus signaling 2	nucleic acid phosphodiester bond hydrolysis	Biological process	11175748
SLC26A9	115019	solute carrier family 26 (anion exchanger), member 9	chloride transport	Biological process	15800055
PDPN	10630	podoplanin	cell proliferation	Biological process	-
RAMP1	10267	receptor (G protein-coupled) activity modifying protein 1	intracellular	Cellular component	-
NOV	4856	nephroblastoma overexpressed	dendrite	Cellular component	-
P2RX4	5025	purinergic receptor P2X, ligand gated ion channel, 4	copper ion binding	Molecular function	12819199
MSX2	4488	msh homeobox 2	cellular response to growth factor stimulus	Biological process	-
IL2RA	3559	interleukin 2 receptor, alpha	activation-induced cell death of T cells	Biological process	-
SLC39A14	23516	solute carrier family 39 (zinc transporter), member 14	Golgi apparatus	Cellular component	-
TEP1	7011	telomerase-associated protein 1	telomerase activity	Molecular function	12135483
ADGRV1	84059	adhesion G protein-coupled receptor V1	G-protein coupled receptor activity	Molecular function	11606593
ANO10	55129	anoctamin 10	cation transmembrane transport	Biological process	22946059
IGKV1-5	28299	immunoglobulin kappa variable 1-5	innate immune response	Biological process	-
CDKN2B	1030	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	regulation of cyclin-dependent protein serine/threonine kinase activity	Biological process	8078588
STC2	8614	stanniocalcin 2	cellular response to hypoxia	Biological process	-
ADAM2	2515	ADAM metallopeptidase domain 2	proteolysis	Biological process	-
DYNC1H1	1778	dynein, cytoplasmic 1, heavy chain 1	establishment of spindle localization	Biological process	23027904
MEF2D	4209	myocyte enhancer factor 2D	apoptotic process	Biological process	-
RYBP	23429	RING1 and YY1 binding protein	apoptotic process	Biological process	-
RIPK1	8737	receptor (TNFRSF)-interacting serine-threonine kinase 1	response to tumor necrosis factor	Biological process	10521396
CRP	1401	C-reactive protein, pentraxin-related	calcium ion binding	Molecular function	23544079
COL15A1	1306	collagen, type XV, alpha 1	cell adhesion	Biological process	9651385
MAP2K4	6416	mitogen-activated protein kinase kinase 4	protein serine/threonine kinase activity	Molecular function	-
ERP27	121506	endoplasmic reticulum protein 27	protein disulfide isomerase activity	Molecular function	-
NEK4	6787	NIMA-related kinase 4	regulation of mitotic cell cycle	Biological process	-
SRC	6714	SRC proto-oncogene, non-receptor tyrosine kinase	stimulatory C-type lectin receptor signaling pathway	Biological process	-
CDC20	991	cell division cycle 20	mitotic cell cycle	Biological process	-
NCSTN	23385	nicastrin	focal adhesion	Cellular component	21423176
AOC2	314	amine oxidase, copper containing 2 (retina-specific)	electron carrier activity	Molecular function	9119395
ABL1	25	ABL proto-oncogene 1, non-receptor tyrosine kinase	B-1 B cell homeostasis	Biological process	-
RPS8	6202	ribosomal protein S8	translation	Biological process	-
MDN1	23195	MDN1, midasin homolog (yeast)	nucleus	Cellular component	12102729
TIMP2	7077	TIMP metallopeptidase inhibitor 2	metal ion binding	Molecular function	-
OARD1	221443	O-acyl-ADP-ribose deacylase 1	purine nucleoside binding	Molecular function	21849506
RUNX1T1	862	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	sequence-specific DNA binding transcription factor activity	Molecular function	-
IL17A	3605	interleukin 17A	inflammatory response	Biological process	-
PSMD2	5708	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	extracellular exosome	Cellular component	20458337
SPARC	6678	secreted protein, acidic, cysteine-rich (osteonectin)	response to lead ion	Biological process	-
RFFL	117584	ring finger and FYVE-like domain containing E3 ubiquitin protein ligase	p53 binding	Molecular function	17121812
MCOLN3	55283	mucolipin 3	plasma membrane	Cellular component	-
ALOX15	246	arachidonate 15-lipoxygenase	regulation of peroxisome proliferator activated receptor signaling pathway	Biological process	-
SLC13A5	284111	solute carrier family 13 (sodium-dependent citrate transporter), member 5	succinate transmembrane transport	Biological process	-
ARSK	153642	arylsulfatase family, member K	extracellular region	Cellular component	-
LOC344967	344967	acyl-CoA thioesterase 7 pseudogene	cytoplasm	Cellular component	-
B3GNT3	10331	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3	galactosyltransferase activity	Molecular function	-
EPS8L2	64787	EPS8-like 2	ruffle membrane	Cellular component	14565974
GSN	2934	gelsolin	programmed cell death	Biological process	-
RRP1B	23076	ribosomal RNA processing 1B	negative regulation of phosphatase activity	Biological process	19389623
CPLX1	10815	complexin 1	synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex	Cellular component	15217342
NSMAF	8439	neutral sphingomyelinase (N-SMase) activation associated factor	positive regulation of catalytic activity	Biological process	-
HMGA2	8091	high mobility group AT-hook 2	nucleus	Cellular component	16791210
YES1	7525	YES proto-oncogene 1, Src family tyrosine kinase	protein tyrosine kinase activity	Molecular function	-
SLC7A6OS	84138	solute carrier family 7, member 6 opposite strand	nucleus	Cellular component	-
GPC4	2239	glypican 4	extracellular exosome	Cellular component	19199708
ST13	6767	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	cytosol	Cellular component	-
TWIST1	7291	twist family bHLH transcription factor 1	muscle organ development	Biological process	-
SMO	6608	smoothened, frizzled class receptor	regulation of heart morphogenesis	Biological process	-
MAL	4118	mal, T-cell differentiation protein	lipid binding	Molecular function	10739088
FASN	2194	fatty acid synthase	3-oxoacyl-[acyl-carrier-protein] synthase activity	Molecular function	-
HOXB3	3213	homeobox B3	embryonic skeletal system morphogenesis	Biological process	-
SPHK1	8877	sphingosine kinase 1	brain development	Biological process	-
OR52E8	390079	olfactory receptor, family 52, subfamily E, member 8	olfactory receptor activity	Molecular function	-
AKT1	207	v-akt murine thymoma viral oncogene homolog 1	identical protein binding	Molecular function	7891724
RRM2	6241	ribonucleotide reductase M2	oxidation-reduction process	Biological process	-
CEP83	51134	centrosomal protein 83kDa	protein binding	Molecular function	23530209
P2RX6	9127	purinergic receptor P2X, ligand gated ion channel, 6	response to ATP	Biological process	-
SLC30A1	7779	solute carrier family 30 (zinc transporter), member 1	transmembrane transport	Biological process	-
SFXN2	118980	sideroflexin 2	ion transmembrane transport	Biological process	-
FOXA2	3170	forkhead box A2	response to interleukin-6	Biological process	15737987
CDCA7	83879	cell division cycle associated 7	regulation of cell proliferation	Biological process	11598121
LHX9	56956	LIM homeobox 9	cell proliferation	Biological process	-
CLEC7A	64581	C-type lectin domain family 7, member A	innate immune response	Biological process	-
SMARCAL1	50485	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1	cellular response to DNA damage stimulus	Biological process	19793862
CDC25B	994	cell division cycle 25B	peptidyl-tyrosine dephosphorylation	Biological process	1836978
EDNRB	1910	endothelin receptor type B	enteric nervous system development	Biological process	-
CDK16	5127	cyclin-dependent kinase 16	neuron projection	Cellular component	-
DIAPH1	1729	diaphanous-related formin 1	cellular response to histamine	Biological process	15123714
GCA	25801	grancalcin, EF-hand calcium binding protein	calcium-dependent cysteine-type endopeptidase activity	Molecular function	-
BMPR2	659	bone morphogenetic protein receptor, type II (serine/threonine kinase)	negative regulation of systemic arterial blood pressure	Biological process	18364108
EVL	51466	Enah/Vasp-like	profilin binding	Molecular function	-
HTR1D	3352	5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled	serotonin receptor activity	Molecular function	1652050
NEDD4	4734	neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase	protein ubiquitination	Biological process	17996703
SIAH2	6478	siah E3 ubiquitin protein ligase 2	ubiquitin conjugating enzyme binding	Molecular function	-
GPR155	151556	G protein-coupled receptor 155	transmembrane transport	Biological process	-
MSLN	10232	mesothelin	protein binding	Molecular function	14676194
PHF5A	84844	PHD finger protein 5A	nucleoplasm	Cellular component	-
IFT22	64792	intraflagellar transport 22	metabolic process	Biological process	-
SCMH1	22955	sex comb on midleg homolog 1 (Drosophila)	transcription, DNA-templated	Biological process	-
FAM21C	253725	family with sequence similarity 21, member C	WASH complex	Cellular component	19922875
CCL5	6352	chemokine (C-C motif) ligand 5	positive regulation of cell-cell adhesion mediated by integrin	Biological process	8558019
TP73	7161	tumor protein p73	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
AGO2	27161	argonaute RISC catalytic component 2	Notch signaling pathway	Biological process	-
TRAF6	7189	TNF receptor-associated factor 6, E3 ubiquitin protein ligase	toll-like receptor TLR1:TLR2 signaling pathway	Biological process	-
HEY2	23493	hes-related family bHLH transcription factor with YRPW motif 2	cardiac septum morphogenesis	Biological process	-
SNX32	254122	sorting nexin 32	phosphatidylinositol binding	Molecular function	-
STAB1	23166	stabilin 1	oxidation-reduction process	Biological process	12077138
TERF2	7014	telomeric repeat binding factor 2	positive regulation of telomere maintenance	Biological process	-
HES1	3280	hes family bHLH transcription factor 1	liver development	Biological process	-
GSTZ1	2954	glutathione S-transferase zeta 1	cellular nitrogen compound metabolic process	Biological process	-
FBXW11	23291	F-box and WD repeat domain containing 11	SCF ubiquitin ligase complex	Cellular component	16880511
GSTO2	119391	glutathione S-transferase omega 2	L-ascorbic acid metabolic process	Biological process	-
NXPH4	11247	neurexophilin 4	neuropeptide signaling pathway	Biological process	9570794
ZBTB20	26137	zinc finger and BTB domain containing 20	transcription, DNA-templated	Biological process	-
NUP93	9688	nucleoporin 93kDa	carbohydrate metabolic process	Biological process	-
POPDC2	64091	popeye domain containing 2	regulation of membrane potential	Biological process	-
NKX2-1	7080	NK2 homeobox 1	phospholipid metabolic process	Biological process	-
SOX9	6662	SRY (sex determining region Y)-box 9	cellular response to retinoic acid	Biological process	12420222
CTSS	1520	cathepsin S	toll-like receptor signaling pathway	Biological process	-
PMP2	5375	peripheral myelin protein 2	cytoplasm	Cellular component	-
SETD3	84193	SET domain containing 3	histone methyltransferase activity (H3-K36 specific)	Molecular function	-
SPATA24	202051	spermatogenesis associated 24	protein binding	Molecular function	25416956
KLC1	3831	kinesin light chain 1	cytosol	Cellular component	-
CABP1	9478	calcium binding protein 1	negative regulation of voltage-gated calcium channel activity	Biological process	-
CMAHP	8418	cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene	cytoplasm	Cellular component	19890979
MYCBP	26292	MYC binding protein	nucleus	Cellular component	9797456
SUV39H1	6839	suppressor of variegation 3-9 homolog 1 (Drosophila)	nucleus	Cellular component	18004385
GRM6	2916	glutamate receptor, metabotropic 6	synaptic transmission	Biological process	-
HAS1	3036	hyaluronan synthase 1	cell adhesion	Biological process	8798544
BCL2A1	597	BCL2-related protein A1	negative regulation of intrinsic apoptotic signaling pathway	Biological process	-
DNMT1	1786	DNA (cytosine-5-)-methyltransferase 1	nucleus	Cellular component	16791210
ATAT1	79969	alpha tubulin acetyltransferase 1	mitotic spindle	Cellular component	23720746
FGFR3	2261	fibroblast growth factor receptor 3	positive regulation of endothelial cell proliferation	Biological process	-
Mar-06	10299	membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase	ubiquitin-protein transferase activity	Molecular function	19651899
ST14	6768	suppression of tumorigenicity 14 (colon carcinoma)	serine-type endopeptidase activity	Molecular function	-
FLII	2314	flightless I homolog (Drosophila)	nucleoplasm	Cellular component	-
TNP1	7141	transition protein 1 (during histone to protamine replacement)	fertilization, exchange of chromosomal proteins	Biological process	12743712
ACTG2	72	actin, gamma 2, smooth muscle, enteric	extracellular space	Cellular component	23580065
PDZK1	5174	PDZ domain containing 1	positive regulation of ion transmembrane transport	Biological process	15523054
RPGRIP1L	23322	RPGRIP1-like	establishment or maintenance of cell polarity	Biological process	-
PPARG	5468	peroxisome proliferator-activated receptor gamma	RNA polymerase II transcription factor complex	Cellular component	9568716
PSEN1	5663	presenilin 1	epithelial cell proliferation	Biological process	-
GTPBP8	29083	GTP-binding protein 8 (putative)	metal ion binding	Molecular function	-
SPATA31A5	727905	SPATA31 subfamily A, member 5	integral component of membrane	Cellular component	-
PRKAR1A	5573	protein kinase, cAMP-dependent, regulatory, type I, alpha	transmembrane transport	Biological process	-
CHAC1	79094	ChaC glutathione-specific gamma-glutamylcyclotransferase 1	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	Biological process	19109178
DNAH5	1767	dynein, axonemal, heavy chain 5	microtubule	Cellular component	-
AK2	204	adenylate kinase 2	cytosol	Cellular component	-
FBXO18	84893	F-box protein, helicase, 18	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage	Biological process	23361013
CLCN2	1181	chloride channel, voltage-sensitive 2	transport	Biological process	7795595
CPS1	1373	carbamoyl-phosphate synthase 1, mitochondrial	nitric oxide metabolic process	Biological process	14718356
GATA3	2625	GATA binding protein 3	positive regulation of interleukin-4 production	Biological process	-
ADCYAP1	116	adenylate cyclase activating polypeptide 1 (pituitary)	positive regulation of ERK1 and ERK2 cascade	Biological process	23800469
PIP5K1B	8395	phosphatidylinositol-4-phosphate 5-kinase, type I, beta	endomembrane system	Cellular component	-
ATXN7	6314	ataxin 7	cytoplasm	Cellular component	-
CDC37	11140	cell division cycle 37	extracellular exosome	Cellular component	20458337
IFNAR1	3454	interferon (alpha, beta and omega) receptor 1	intracellular	Cellular component	7665574
FGF18	8817	fibroblast growth factor 18	positive regulation of ERK1 and ERK2 cascade	Biological process	16756958
ARL3	403	ADP-ribosylation factor-like 3	midbody	Cellular component	16525022
ZNF436	80818	zinc finger protein 436	nucleoplasm	Cellular component	-
TRDN	10345	triadin	ion transmembrane transport	Biological process	-
APH1A	51107	APH1A gamma secretase subunit	apoptotic signaling pathway	Biological process	-
CXCL10	3627	chemokine (C-X-C motif) ligand 10	cell surface receptor signaling pathway	Biological process	10903763
SMO	6608	smoothened, frizzled class receptor	midgut development	Biological process	-
ZBTB16	7704	zinc finger and BTB domain containing 16	nuclear speck	Cellular component	8541544
RFC5	5985	replication factor C (activator 1) 5, 36.5kDa	DNA replication factor C complex	Cellular component	9488738
MCU	90550	mitochondrial calcium uniporter	protein complex oligomerization	Biological process	21685886
ATIC	471	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	purine nucleobase metabolic process	Biological process	-
DNAH17	8632	dynein, axonemal, heavy chain 17	metabolic process	Biological process	9373155
RAB33B	83452	RAB33B, member RAS oncogene family	autophagy	Biological process	-
DCPS	28960	decapping enzyme, scavenger	cytoplasm	Cellular component	-
KLF5	688	Kruppel-like factor 5 (intestinal)	microvillus assembly	Biological process	-
ZNF546	339327	zinc finger protein 546	DNA binding	Molecular function	-
RARA	5914	retinoic acid receptor, alpha	nucleoplasm	Cellular component	-
CDC25B	994	cell division cycle 25B	mitotic nuclear division	Biological process	-
CLEC4F	165530	C-type lectin domain family 4, member F	NK T cell activation	Biological process	-
ZNF263	10127	zinc finger protein 263	nucleus	Cellular component	-
PABPC4	8761	poly(A) binding protein, cytoplasmic 4 (inducible form)	cytoplasm	Cellular component	-
INCA1	388324	inhibitor of CDK, cyclin A1 interacting protein 1	negative regulation of cyclin-dependent protein serine/threonine kinase activity	Biological process	21540187
PAIP2	51247	poly(A) binding protein interacting protein 2	mRNA binding	Molecular function	-
HCN3	57657	hyperpolarization activated cyclic nucleotide gated potassium channel 3	cAMP binding	Molecular function	-
MCRS1	10445	microspherule protein 1	chromatin organization	Biological process	-
CHD9	80205	chromodomain helicase DNA binding protein 9	ATP binding	Molecular function	-
CLEC6A	93978	C-type lectin domain family 6, member A	stimulatory C-type lectin receptor signaling pathway	Biological process	-
APC	324	adenomatous polyposis coli	positive regulation of cell migration	Biological process	17192415
PDSS2	57107	prenyl (decaprenyl) diphosphate synthase, subunit 2	ubiquinone biosynthetic process	Biological process	-
IGF1	3479	insulin-like growth factor 1 (somatomedin C)	negative regulation of apoptotic process	Biological process	11949853
TBCD	6904	tubulin folding cofactor D	GTPase activator activity	Molecular function	10831612
ARHGAP35	2909	Rho GTPase activating protein 35	GTP binding	Molecular function	-
CANX	821	calnexin	protein folding in endoplasmic reticulum	Biological process	22013210
HECTD3	79654	HECT domain containing E3 ubiquitin protein ligase 3	cytoplasm	Cellular component	-
HRG	3273	histidine-rich glycoprotein	regulation of protein complex assembly	Biological process	16489009
SLC25A17	10478	solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17	NAD transport	Biological process	22185573
SERPINA6	866	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6	steroid binding	Molecular function	18513745
S1PR2	9294	sphingosine-1-phosphate receptor 2	positive regulation of establishment of endothelial barrier	Biological process	24851274
RPL3L	6123	ribosomal protein L3-like	SRP-dependent cotranslational protein targeting to membrane	Biological process	-
RPL35A	6165	ribosomal protein L35a	translational elongation	Biological process	-
CCNA1	8900	cyclin A1	protein binding	Molecular function	15232106
ATP6V1C2	245973	ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2	cellular iron ion homeostasis	Biological process	-
PIPOX	51268	pipecolic acid oxidase	L-lysine catabolic process to acetyl-CoA via L-pipecolate	Biological process	10642506
ACVR2B	93	activin A receptor, type IIB	transmembrane receptor protein serine/threonine kinase signaling pathway	Biological process	8161782
FAM90A24P	441332	family with sequence similarity 90, member A24 (pseudogene)	nucleic acid binding	Molecular function	-
UTP15	84135	UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)	poly(A) RNA binding	Molecular function	22658674
HLA-C	3107	major histocompatibility complex, class I, C	ER to Golgi transport vesicle membrane	Cellular component	-
NAPRT	93100	nicotinate phosphoribosyltransferase	nicotinate phosphoribosyltransferase activity	Molecular function	-
INPP1	3628	inositol polyphosphate-1-phosphatase	phosphatidylinositol phosphorylation	Biological process	-
PPARA	5465	peroxisome proliferator-activated receptor alpha	cellular lipid metabolic process	Biological process	-
ABCD1	215	ATP-binding cassette, sub-family D (ALD), member 1	membrane	Cellular component	19946888
KLF14	136259	Kruppel-like factor 14	metal ion binding	Molecular function	-
CUL7	9820	cullin 7	anaphase-promoting complex	Cellular component	12481031
TYMS	7298	thymidylate synthetase	pyrimidine nucleoside biosynthetic process	Biological process	-
EDN1	1906	endothelin 1	sensory perception of pain	Biological process	-
LHX6	26468	LIM homeobox 6	forebrain neuron fate commitment	Biological process	-
ZNF281	23528	zinc finger protein 281	sequence-specific DNA binding transcription factor activity	Molecular function	10448078
IL17F	112744	interleukin 17F	negative regulation of angiogenesis	Biological process	11591732
PCID2	55795	PCI domain containing 2	cellular_component	Cellular component	-
HLA-DRB3	3125	major histocompatibility complex, class II, DR beta 3	Golgi membrane	Cellular component	-
VTI1B	10490	vesicle transport through interaction with t-SNAREs 1B	recycling endosome	Cellular component	18570918
CHRND	1144	cholinergic receptor, nicotinic, delta (muscle)	cation transmembrane transport	Biological process	8872460
ADGRG1	9289	adhesion G protein-coupled receptor G1	integral component of plasma membrane	Cellular component	10049584
MMP9	4318	matrix metallopeptidase 9	endodermal cell differentiation	Biological process	23154389
C6	729	complement component 6	positive regulation of activation of membrane attack complex	Biological process	-
GDF2	2658	growth differentiation factor 2	negative regulation of angiogenesis	Biological process	20406889
PHPT1	29085	phosphohistidine phosphatase 1	extracellular exosome	Cellular component	19056867
PTK2B	2185	protein tyrosine kinase 2 beta	positive regulation of JNK cascade	Biological process	8670418
COG8	84342	component of oligomeric golgi complex 8	protein transport	Biological process	-
TAF1A	9015	TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa	microtubule cytoskeleton	Cellular component	-
CDR2	1039	cerebellar degeneration-related protein 2, 62kDa	molecular_function	Molecular function	-
CCL7	6354	chemokine (C-C motif) ligand 7	extracellular region	Cellular component	-
ELP3	55140	elongator acetyltransferase complex subunit 3	cytoplasm	Cellular component	-
CTSA	5476	cathepsin A	dolichol-linked oligosaccharide biosynthetic process	Biological process	-
ITGA11	22801	integrin, alpha 11	cell adhesion mediated by integrin	Biological process	11518510
ATP2B4	493	ATPase, Ca++ transporting, plasma membrane 4	sodium channel regulator activity	Molecular function	-
XPC	7508	xeroderma pigmentosum, complementation group C	extracellular exosome	Cellular component	23376485
TACR1	6869	tachykinin receptor 1	detection of abiotic stimulus	Biological process	9537323
FASTKD5	60493	FAST kinase domains 5	protein kinase activity	Molecular function	-
MMP14	4323	matrix metallopeptidase 14 (membrane-inserted)	positive regulation of peptidase activity	Biological process	-
TSPAN15	23555	tetraspanin 15	establishment of protein localization to plasma membrane	Biological process	23091066
CXCL13	10563	chemokine (C-X-C motif) ligand 13	receptor agonist activity	Molecular function	11554781
SARM1	23098	sterile alpha and TIR motif containing 1	regulation of dendrite morphogenesis	Biological process	-
TNFRSF1A	7132	tumor necrosis factor receptor superfamily, member 1A	tumor necrosis factor-mediated signaling pathway	Biological process	-
HGFAC	3083	HGF activator	serine-type endopeptidase activity	Molecular function	-
CHRNA2	1135	cholinergic receptor, nicotinic, alpha 2 (neuronal)	plasma membrane	Cellular component	-
TNFSF4	7292	tumor necrosis factor (ligand) superfamily, member 4	cellular response to lipopolysaccharide	Biological process	20844189
NSG1	27065	neuron specific gene family member 1	cytoplasm	Cellular component	9013775
EIF2AK3	9451	eukaryotic translation initiation factor 2-alpha kinase 3	positive regulation of protein binding	Biological process	-
CLMP	79827	CXADR-like membrane protein	cytoplasmic microtubule	Cellular component	23264731
CHSY1	22856	chondroitin sulfate synthase 1	small molecule metabolic process	Biological process	-
PRKACA	5566	protein kinase, cAMP-dependent, catalytic, alpha	innate immune response	Biological process	-
NCKAP1	10787	NCK-associated protein 1	vascular endothelial growth factor receptor signaling pathway	Biological process	-
ADGRE5	976	adhesion G protein-coupled receptor E5	extracellular exosome	Cellular component	20458337
TRAPPC2	6399	trafficking protein particle complex 2	transcription, DNA-templated	Biological process	-
WNT7A	7476	wingless-type MMTV integration site family, member 7A	neuron differentiation	Biological process	-
RPL14	9045	ribosomal protein L14	cytosolic large ribosomal subunit	Cellular component	12962325
CYP27A1	1593	cytochrome P450, family 27, subfamily A, polypeptide 1	steroid hydroxylase activity	Molecular function	9790667
ATP7A	538	ATPase, Cu++ transporting, alpha polypeptide	dopamine metabolic process	Biological process	-
MAGI1	9223	membrane associated guanylate kinase, WW and PDZ domain containing 1	neuron death	Biological process	22166940
OR10D3	26497	olfactory receptor, family 10, subfamily D, member 3 (non-functional)	olfactory receptor activity	Molecular function	-
RIC8A	60626	RIC8 guanine nucleotide exchange factor A	cell migration involved in gastrulation	Biological process	-
BBS2	583	Bardet-Biedl syndrome 2	cilium morphogenesis	Biological process	-
PSME3	10197	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)	membrane	Cellular component	19946888
ECT2	1894	epithelial cell transforming 2	cellular response to calcium ion	Biological process	15254234
HTR2B	3357	5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled	negative regulation of apoptotic process	Biological process	-
IL1B	3553	interleukin 1, beta	positive regulation of monocyte chemotactic protein-1 production	Biological process	19524870
MAPRE3	22924	microtubule-associated protein, RP/EB family, member 3	midbody	Cellular component	17310996
CCDC172	374355	coiled-coil domain containing 172	protein binding	Molecular function	25416956
GSK3B	2932	glycogen synthase kinase 3 beta	negative regulation of protein complex assembly	Biological process	16188939
OGFOD1	55239	2-oxoglutarate and iron-dependent oxygenase domain containing 1	cell proliferation	Biological process	24550447
RSL1D1	26156	ribosomal L1 domain containing 1	membrane	Cellular component	16210410
RBM27	54439	RNA binding motif protein 27	nucleoplasm	Cellular component	-
TRAK1	22906	trafficking protein, kinesin binding 1	nucleus	Cellular component	-
KCNC1	3746	potassium channel, voltage gated Shaw related subfamily C, member 1	synaptic transmission	Biological process	-
SOX5	6660	SRY (sex determining region Y)-box 5	transcription regulatory region DNA binding	Molecular function	-
ATF6B	1388	activating transcription factor 6 beta	sequence-specific DNA binding	Molecular function	-
PSMC6	5706	proteasome (prosome, macropain) 26S subunit, ATPase, 6	proteasome complex	Cellular component	17323924
KDF1	126695	keratinocyte differentiation factor 1	establishment of skin barrier	Biological process	-
ZNF532	55205	zinc finger protein 532	nucleus	Cellular component	-
TAB1	10454	TGF-beta activated kinase 1/MAP3K7 binding protein 1	endosome membrane	Cellular component	-
PDE1C	5137	phosphodiesterase 1C, calmodulin-dependent 70kDa	fibroblast growth factor receptor signaling pathway	Biological process	-
LDLRAP1	26119	low density lipoprotein receptor adaptor protein 1	early endosome	Cellular component	14528014
ACBD5	91452	acyl-CoA binding domain containing 5	aggrephagy	Biological process	24535825
BTBD6	90135	BTB (POZ) domain containing 6	cytoplasmic mRNA processing body	Cellular component	-
DEPDC7	91614	DEP domain containing 7	regulation of small GTPase mediated signal transduction	Biological process	-
TRAF2	7186	TNF receptor-associated factor 2	cytoplasmic side of plasma membrane	Cellular component	-
PYCARD	29108	PYD and CARD domain containing	IkappaB kinase complex	Cellular component	12656673
UBXN8	7993	UBX domain protein 8	protein binding	Molecular function	21949850
CFL2	1073	cofilin 2 (muscle)	positive regulation of actin filament depolymerization	Biological process	17160903
NUBP1	4682	nucleotide binding protein 1	4 iron, 4 sulfur cluster binding	Molecular function	-
APOA1	335	apolipoprotein A-I	regulation of protein phosphorylation	Biological process	-
TUBA1C	84790	tubulin, alpha 1c	microtubule	Cellular component	12090300
VTI1B	10490	vesicle transport through interaction with t-SNAREs 1B	vesicle	Cellular component	18570918
DEFB104A	140596	defensin, beta 104A	cell surface	Cellular component	-
LCA5	167691	Leber congenital amaurosis 5	cytoplasm	Cellular component	-
LILRB1	10859	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	HLA-B specific inhibitory MHC class I receptor activity	Molecular function	11907092
HSP90AA1	3320	heat shock protein 90kDa alpha (cytosolic), class A member 1	GTPase binding	Molecular function	24337748
CYTH1	9267	cytohesin 1	protein binding	Molecular function	11867758
MYBPHL	343263	myosin binding protein H-like	molecular_function	Molecular function	-
ERBB2IP	55914	erbb2 interacting protein	nucleus	Cellular component	11375975
TBP	6908	TATA box binding protein	transcription elongation from RNA polymerase I promoter	Biological process	-
RAB27B	5874	RAB27B, member RAS oncogene family	apical plasma membrane	Cellular component	-
RAB10	10890	RAB10, member RAS oncogene family	cytoplasmic vesicle membrane	Cellular component	-
SLC16A5	9121	solute carrier family 16 (monocarboxylate transporter), member 5	plasma membrane lactate transport	Biological process	-
CEP131	22994	centrosomal protein 131kDa	nucleus	Cellular component	-
CASP6	839	caspase 6, apoptosis-related cysteine peptidase	cytoplasm	Cellular component	-
GPD1L	23171	glycerol-3-phosphate dehydrogenase 1-like	plasma membrane	Cellular component	17967977
NUMB	8650	numb homolog (Drosophila)	positive regulation of polarized epithelial cell differentiation	Biological process	-
RPL29	6159	ribosomal protein L29	viral process	Biological process	-
NPRL3	8131	nitrogen permease regulator-like 3 (S. cerevisiae)	aorta morphogenesis	Biological process	-
TP73	7161	tumor protein p73	chromatin binding	Molecular function	-
KAT2A	2648	K(lysine) acetyltransferase 2A	cell proliferation	Biological process	-
ADAM17	6868	ADAM metallopeptidase domain 17	response to high density lipoprotein particle	Biological process	17786981
ZBTB16	7704	zinc finger and BTB domain containing 16	apoptotic process	Biological process	9294197
PRKX	5613	protein kinase, X-linked	nucleus	Cellular component	-
CACNA1F	778	calcium channel, voltage-dependent, L type, alpha 1F subunit	integral component of membrane	Cellular component	15897456
ZNF790	388536	zinc finger protein 790	regulation of transcription, DNA-templated	Biological process	-
UBD	10537	ubiquitin D	positive regulation of apoptotic process	Biological process	16495380
MIS18A	54069	MIS18 kinetochore protein A	CENP-A containing nucleosome assembly	Biological process	-
STXBP5L	9515	syntaxin binding protein 5-like	protein transport	Biological process	-
JOSD1	9929	Josephin domain containing 1	protein binding	Molecular function	21516116
PGAM2	5224	phosphoglycerate mutase 2 (muscle)	dephosphorylation	Biological process	-
RAB3A	5864	RAB3A, member RAS oncogene family	regulation of short-term neuronal synaptic plasticity	Biological process	-
ACHE	43	acetylcholinesterase (Yt blood group)	basal lamina	Cellular component	16289501
NCBP2	22916	nuclear cap binding protein subunit 2, 20kDa	snRNA export from nucleus	Biological process	7651522
GCHFR	2644	GTP cyclohydrolase I feedback regulator	nucleus	Cellular component	16778797
ELF4	2000	E74-like factor 4 (ets domain transcription factor)	protein binding	Molecular function	10207087
SOX12	6666	SRY (sex determining region Y)-box 12	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
FKBP6	8468	FK506 binding protein 6, 36kDa	cell differentiation	Biological process	-
WNK3	65267	WNK lysine deficient protein kinase 3	positive regulation of peptidyl-threonine phosphorylation	Biological process	16275913
HPS4	89781	Hermansky-Pudlak syndrome 4	blood coagulation	Biological process	-
MFN2	9927	mitofusin 2	blastocyst formation	Biological process	-
FKBP4	2288	FK506 binding protein 4, 59kDa	endoplasmic reticulum membrane	Cellular component	-
HBEGF	1839	heparin-binding EGF-like growth factor	epidermal growth factor receptor signaling pathway	Biological process	-
COLEC12	81035	collectin sub-family member 12	defense response	Biological process	11162630
HNF1B	6928	HNF1 homeobox B	nucleus	Cellular component	15355349
APOA1	335	apolipoprotein A-I	negative chemotaxis	Biological process	23726972
ADAM10	102	ADAM metallopeptidase domain 10	epidermal growth factor receptor signaling pathway	Biological process	-
FNBP1L	54874	formin binding protein 1-like	positive regulation of filopodium assembly	Biological process	20730103
KLHDC3	116138	kelch domain containing 3	chromatin binding	Molecular function	12606021
QRSL1	55278	glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity	Molecular function	19805282
FKBP7	51661	FK506 binding protein 7	calcium ion binding	Molecular function	-
ZBTB17	7709	zinc finger and BTB domain containing 17	transcription, DNA-templated	Biological process	-
GPR176	11245	G protein-coupled receptor 176	integral component of plasma membrane	Cellular component	7893747
CAPN2	824	calpain 2, (m/II) large subunit	pseudopodium	Cellular component	14559243
PCNXL4	64430	pecanex-like 4 (Drosophila)	protein binding	Molecular function	16237761
SULT1A1	6817	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1	protein binding	Molecular function	25416956
CAV3	859	caveolin 3	protein localization	Biological process	-
SERPINB9	5272	serpin peptidase inhibitor, clade B (ovalbumin), member 9	mast cell mediated immunity	Biological process	15739160
FOXA1	3169	forkhead box A1	positive regulation of cell-cell adhesion mediated by cadherin	Biological process	20160041
CTSV	1515	cathepsin V	response to gonadotropin	Biological process	-
DNAJC2	27000	DnaJ (Hsp40) homolog, subfamily C, member 2	Hsp70 protein binding	Molecular function	16002468
MYO6	4646	myosin VI	protein binding	Molecular function	11447109
RHBG	57127	Rh family, B glycoprotein (gene/pseudogene)	plasma membrane	Cellular component	-
DPP10	57628	dipeptidyl-peptidase 10 (non-functional)	plasma membrane	Cellular component	-
LPCAT4	254531	lysophosphatidylcholine acyltransferase 4	cellular lipid metabolic process	Biological process	-
PBRM1	55193	polybromo 1	DNA binding	Molecular function	-
VCAN	1462	versican	extracellular space	Cellular component	20551380
SLAMF7	57823	SLAM family member 7	natural killer cell mediated cytotoxicity	Biological process	11698418
ZNF839	55778	zinc finger protein 839	metal ion binding	Molecular function	-
UBR2	23304	ubiquitin protein ligase E3 component n-recognin 2	male meiosis I	Biological process	-
PCGF6	84108	polycomb group ring finger 6	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	-
WDFY3	23001	WD repeat and FYVE domain containing 3	endomembrane system	Cellular component	-
ZWINT	11130	ZW10 interacting kinetochore protein	condensed chromosome kinetochore	Cellular component	-
LIPG	9388	lipase, endothelial	early endosome	Cellular component	23918928
RGS10	6001	regulator of G-protein signaling 10	nucleus	Cellular component	10791963
SLC25A17	10478	solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17	peroxisome	Cellular component	9874197
PSMA5	5686	proteasome (prosome, macropain) subunit, alpha type, 5	proteasomal ubiquitin-independent protein catabolic process	Biological process	-
VPS37C	55048	vacuolar protein sorting 37 homolog C (S. cerevisiae)	viral process	Biological process	-
HPCAL4	51440	hippocalcin like 4	signal transduction	Biological process	-
ITGAM	3684	integrin, alpha M (complement component 3 receptor 3 subunit)	activated T cell proliferation	Biological process	-
RPSA	3921	ribosomal protein SA	translation	Biological process	-
S100A12	6283	S100 calcium binding protein A12	defense response to bacterium	Biological process	18443896
PITX2	5308	paired-like homeodomain 2	chromatin DNA binding	Molecular function	-
DAB2IP	153090	DAB2 interacting protein	identical protein binding	Molecular function	12813029
RAC2	5880	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	phagocytic vesicle membrane	Cellular component	-
PEA15	8682	phosphoprotein enriched in astrocytes 15	carbohydrate transport	Biological process	-
MYL6B	140465	myosin, light chain 6B, alkali, smooth muscle and non-muscle	muscle filament sliding	Biological process	2304459
Sep-02	4735	septin 2	perinuclear region of cytoplasm	Cellular component	-
TIAM1	7074	T-cell lymphoma invasion and metastasis 1	Rac protein signal transduction	Biological process	20361982
MAP2K5	5607	mitogen-activated protein kinase kinase 5	positive regulation of epithelial cell proliferation	Biological process	-
SGCB	6443	sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)	cardiac muscle cell development	Biological process	-
MORC3	23515	MORC family CW-type zinc finger 3	nucleoplasm	Cellular component	-
POLR1E	64425	polymerase (RNA) I polypeptide E, 53kDa	DNA-directed RNA polymerase I complex	Cellular component	-
SCART1	619207	scavenger receptor protein family member	integral component of membrane	Cellular component	-
HIST1H4A	8359	histone cluster 1, H4a	DNA replication-independent nucleosome assembly	Biological process	14718166
BCL2L14	79370	BCL2-like 14 (apoptosis facilitator)	intracellular organelle	Cellular component	11054413
CYP11B1	1584	cytochrome P450, family 11, subfamily B, polypeptide 1	glucose homeostasis	Biological process	16114325
STAR	6770	steroidogenic acute regulatory protein	glucocorticoid metabolic process	Biological process	-
TMSB4X	7114	thymosin beta 4, X-linked	cytosol	Cellular component	-
DDX19B	11269	DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B	extracellular exosome	Cellular component	19056867
ME3	10873	malic enzyme 3, NADP(+)-dependent, mitochondrial	oxidation-reduction process	Biological process	7818469
MMP2	4313	matrix metallopeptidase 2	serine-type endopeptidase activity	Molecular function	-
TIMMDC1	51300	translocase of inner mitochondrial membrane domain containing 1	integral component of membrane	Cellular component	-
MISP	126353	mitotic spindle positioning	focal adhesion	Cellular component	-
MT3	4504	metallothionein 3	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	Molecular function	16387743
YWHAB	7529	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta	insulin receptor signaling pathway	Biological process	-
TNKS	8658	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase	mitotic spindle organization	Biological process	17026964
GPC1	2817	glypican 1	integral component of plasma membrane	Cellular component	2148568
TNFAIP3	7128	tumor necrosis factor, alpha-induced protein 3	DNA binding	Molecular function	-
GRM7	2917	glutamate receptor, metabotropic 7	sensory perception of sound	Biological process	19047183
P3H1	64175	prolyl 3-hydroxylase 1	cell growth	Biological process	-
SIRT3	23410	sirtuin 3	membrane	Cellular component	-
KCND2	3751	potassium channel, voltage gated Shal related subfamily D, member 2	delayed rectifier potassium channel activity	Molecular function	-
NNMT	4837	nicotinamide N-methyltransferase	organ regeneration	Biological process	-
MAPK1	5594	mitogen-activated protein kinase 1	early endosome	Cellular component	19565474
SRGAP3	9901	SLIT-ROBO Rho GTPase activating protein 3	regulation of small GTPase mediated signal transduction	Biological process	-
XRN2	22803	5'-3' exoribonuclease 2	RNA metabolic process	Biological process	-
RPS14	6208	ribosomal protein S14	translational termination	Biological process	-
EI24	9538	etoposide induced 2.4	Golgi apparatus	Cellular component	-
PLA2G10	8399	phospholipase A2, group X	phospholipid metabolic process	Biological process	-
NR2E3	10002	nuclear receptor subfamily 2, group E, member 3	nucleoplasm	Cellular component	-
EIF4G3	8672	eukaryotic translation initiation factor 4 gamma, 3	cytosol	Cellular component	-
MRE11A	4361	MRE11 meiotic recombination 11 homolog A (S. cerevisiae)	innate immune response	Biological process	-
SLC12A1	6557	solute carrier family 12 (sodium/potassium/chloride transporter), member 1	chloride transport	Biological process	8640224
HSPD1	3329	heat shock 60kDa protein 1 (chaperonin)	positive regulation of T cell activation	Biological process	-
MARK3	4140	MAP/microtubule affinity-regulating kinase 3	protein serine/threonine kinase activity	Molecular function	16980613
ELP2	55250	elongator acetyltransferase complex subunit 2	cytoplasm	Cellular component	11714725
UGT1A6	54578	UDP glucuronosyltransferase 1 family, polypeptide A6	negative regulation of cellular glucuronidation	Biological process	20610558
CAMK2N2	94032	calcium/calmodulin-dependent protein kinase II inhibitor 2	protein kinase binding	Molecular function	-
DBN1	1627	drebrin 1	protein binding	Molecular function	12577067
EDN2	1907	endothelin 2	macrophage activation	Biological process	12207323
LHX1	3975	LIM homeobox 1	uterine epithelium development	Biological process	-
SDCBP	6386	syndecan binding protein (syntenin)	cytoskeleton	Cellular component	9391086
SPHK1	8877	sphingosine kinase 1	D-erythro-sphingosine kinase activity	Molecular function	10863092
PHGDH	26227	phosphoglycerate dehydrogenase	neural tube development	Biological process	-
TNFSF9	8744	tumor necrosis factor (ligand) superfamily, member 9	plasma membrane	Cellular component	-
EIF4G1	1981	eukaryotic translation initiation factor 4 gamma, 1	regulation of translational initiation	Biological process	8961935
CSPG4	1464	chondroitin sulfate proteoglycan 4	cell proliferation	Biological process	-
CDH1	999	cadherin 1, type 1, E-cadherin (epithelial)	positive regulation of transcription, DNA-templated	Biological process	16338932
CSRNP2	81566	cysteine-serine-rich nuclear protein 2	negative regulation of phosphatase activity	Biological process	19389623
YKT6	10652	YKT6 v-SNARE homolog (S. cerevisiae)	protein transport	Biological process	-
LANCL1	10314	LanC lantibiotic synthetase component C-like 1 (bacterial)	cytoplasm	Cellular component	-
NOS3	4846	nitric oxide synthase 3 (endothelial cell)	positive regulation of angiogenesis	Biological process	-
GHR	2690	growth hormone receptor	insulin-like growth factor receptor signaling pathway	Biological process	7565946
WWTR1	25937	WW domain containing transcription regulator 1	protein ubiquitination	Biological process	-
SNX1	6642	sorting nexin 1	protein binding	Molecular function	11102511
GNPAT	8443	glyceronephosphate O-acyltransferase	paranodal junction assembly	Biological process	-
LECT1	11061	leukocyte cell derived chemotaxin 1	proteoglycan metabolic process	Biological process	10103018
PTPRC	5788	protein tyrosine phosphatase, receptor type, C	positive regulation of hematopoietic stem cell migration	Biological process	21911094
AR	367	androgen receptor	RNA polymerase II transcription factor binding	Molecular function	16120611
BECN1	8678	beclin 1, autophagy related	protein binding	Molecular function	16417406
TAAR5	9038	trace amine associated receptor 5	integral component of membrane	Cellular component	15718104
KRT1	3848	keratin 1, type II	blood microparticle	Cellular component	22516433
SUPT5H	6829	suppressor of Ty 5 homolog (S. cerevisiae)	DSIF complex	Cellular component	9450929
NRP1	8829	neuropilin 1	facioacoustic ganglion development	Biological process	-
UROC1	131669	urocanate hydratase 1	small molecule metabolic process	Biological process	-
FXYD3	5349	FXYD domain containing ion transport regulator 3	chloride channel activity	Molecular function	-
RCE1	9986	Ras converting CAAX endopeptidase 1	proteolysis	Biological process	10085068
HTATIP2	10553	HIV-1 Tat interactive protein 2, 30kDa	apoptotic process	Biological process	-
TNFSF9	8744	tumor necrosis factor (ligand) superfamily, member 9	tumor necrosis factor receptor binding	Molecular function	-
IGF1R	3480	insulin-like growth factor 1 receptor	insulin-like growth factor binding	Molecular function	1846292
C8orf74	203076	chromosome 8 open reading frame 74	protein binding	Molecular function	23455924
OR9K2	441639	olfactory receptor, family 9, subfamily K, member 2	odorant binding	Molecular function	-
OTULIN	90268	OTU deubiquitinase with linear linkage specificity	LUBAC complex	Cellular component	-
FOXE3	2301	forkhead box E3	cell differentiation	Biological process	-
TIAF1	9220	TGFB1-induced anti-apoptotic factor 1	I-kappaB kinase/NF-kappaB signaling	Biological process	9918798
DDX46	9879	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46	mRNA splicing, via spliceosome	Biological process	-
REL	5966	v-rel avian reticuloendotheliosis viral oncogene homolog	NIK/NF-kappaB signaling	Biological process	-
SEC24B	10427	SEC24 family member B	Golgi membrane	Cellular component	-
RHOB	388	ras homolog family member B	plasma membrane	Cellular component	-
CUL4B	8450	cullin 4B	DNA damage response, detection of DNA damage	Biological process	-
SLC11A1	6556	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1	inflammatory response	Biological process	-
LPL	4023	lipoprotein lipase	triglyceride biosynthetic process	Biological process	-
DAG1	1605	dystroglycan 1 (dystrophin-associated glycoprotein 1)	membrane raft	Cellular component	-
NOS1	4842	nitric oxide synthase 1 (neuronal)	regulation of cardiac muscle contraction	Biological process	9892689
PIP5K1A	8394	phosphatidylinositol-4-phosphate 5-kinase, type I, alpha	activation of GTPase activity	Biological process	20660631
ACVR2B	93	activin A receptor, type IIB	artery development	Biological process	-
CILP	8483	cartilage intermediate layer protein, nucleotide pyrophosphohydrolase	negative regulation of insulin-like growth factor receptor signaling pathway	Biological process	12746903
RAB11FIP5	26056	RAB11 family interacting protein 5 (class I)	insulin secretion involved in cellular response to glucose stimulus	Biological process	-
PPP2CB	5516	protein phosphatase 2, catalytic subunit, beta isozyme	apoptotic mitochondrial changes	Biological process	-
ENG	2022	endoglin	venous blood vessel morphogenesis	Biological process	8194490
AK3	50808	adenylate kinase 3	ITP metabolic process	Biological process	11485571
UQCRC2	7385	ubiquinol-cytochrome c reductase core protein II	aerobic respiration	Biological process	8288258
GBF1	8729	golgi brefeldin A resistant guanine nucleotide exchange factor 1	COPI coating of Golgi vesicle	Biological process	-
GAS6	2621	growth arrest-specific 6	cellular response to interferon-alpha	Biological process	19657094
CD34	947	CD34 molecule	external side of plasma membrane	Cellular component	10337918
CLIC4	25932	chloride intracellular channel 4	intracellular	Cellular component	-
NR4A1	3164	nuclear receptor subfamily 4, group A, member 1	cellular response to vascular endothelial growth factor stimulus	Biological process	18059339
MACF1	23499	microtubule-actin crosslinking factor 1	wound healing	Biological process	-
MBOAT7	79143	membrane bound O-acyltransferase domain containing 7	glycerophospholipid biosynthetic process	Biological process	-
FBF1	85302	Fas (TNFRSF6) binding factor 1	cytosol	Cellular component	-
FAM20A	54757	family with sequence similarity 20, member A	calcium ion homeostasis	Biological process	23434854
INO80C	125476	INO80 complex subunit C	Ino80 complex	Cellular component	21303910
WIPI1	55062	WD repeat domain, phosphoinositide interacting 1	receptor binding	Molecular function	15602573
DTNBP1	84062	dystrobrevin binding protein 1	growth cone	Cellular component	-
MPO	4353	myeloperoxidase	response to gold nanoparticle	Biological process	-
SPAG9	9043	sperm associated antigen 9	cytoplasm	Cellular component	-
SLIT3	6586	slit homolog 3 (Drosophila)	calcium ion binding	Molecular function	9813312
EXOSC5	56915	exosome component 5	U4 snRNA 3'-end processing	Biological process	-
HES4	57801	hes family bHLH transcription factor 4	nucleus	Cellular component	-
NEU2	4759	sialidase 2 (cytosolic sialidase)	sphingolipid metabolic process	Biological process	-
NR1D2	9975	nuclear receptor subfamily 1, group D, member 2	gene expression	Biological process	-
ABCA9	10350	ATP-binding cassette, sub-family A (ABC1), member 9	integral component of membrane	Cellular component	-
CITED1	4435	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1	response to interleukin-1	Biological process	-
HIST1H3H	8357	histone cluster 1, H3h	blood coagulation	Biological process	-
KIF15	56992	kinesin family member 15	plus-end kinesin complex	Cellular component	10878014
DIABLO	56616	diablo, IAP-binding mitochondrial protein	CD40 receptor complex	Cellular component	-
RANBP1	5902	RAN binding protein 1	GDP-dissociation inhibitor activity	Molecular function	7616957
MBD4	8930	methyl-CpG binding domain protein 4	nucleus	Cellular component	9774669
RPLP0P6	220717	ribosomal protein, large, P0 pseudogene 6	molecular_function	Molecular function	-
LRP6	4040	low density lipoprotein receptor-related protein 6	convergent extension	Biological process	-
TNFRSF10B	8795	tumor necrosis factor receptor superfamily, member 10b	activation of NF-kappaB-inducing kinase activity	Biological process	11464292
PGAM4	441531	phosphoglycerate mutase family member 4	positive regulation of sperm motility	Biological process	22590500
NUDT7	283927	nudix (nucleoside diphosphate linked moiety X)-type motif 7	peroxisome	Cellular component	-
GABRR3	200959	gamma-aminobutyric acid (GABA) A receptor, rho 3 (gene/pseudogene)	chloride transmembrane transport	Biological process	-
RAB10	10890	RAB10, member RAS oncogene family	protein secretion	Biological process	-
PCBP2	5094	poly(rC) binding protein 2	nucleoplasm	Cellular component	-
ALG10	84920	ALG10, alpha-1,2-glucosyltransferase	endoplasmic reticulum membrane	Cellular component	-
SDR42E1	93517	short chain dehydrogenase/reductase family 42E, member 1	integral component of membrane	Cellular component	-
MAX	4149	MYC associated factor X	sequence-specific DNA binding transcription factor activity	Molecular function	-
GCC1	79571	GRIP and coiled-coil domain containing 1	protein targeting to Golgi	Biological process	-
EZR	7430	ezrin	vesicle	Cellular component	19190083
OR13C6P	392311	olfactory receptor, family 13, subfamily C, member 6 pseudogene	sensory perception of smell	Biological process	-
ANKIB1	54467	ankyrin repeat and IBR domain containing 1	zinc ion binding	Molecular function	-
LCP2	3937	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	transmembrane receptor protein tyrosine kinase signaling pathway	Biological process	7706237
ABCC5	10057	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	small molecule metabolic process	Biological process	-
HMOX1	3162	heme oxygenase 1	negative regulation of leukocyte migration	Biological process	14525760
C6orf15	29113	chromosome 6 open reading frame 15	laminin binding	Molecular function	-
ATL2	64225	atlastin GTPase 2	endoplasmic reticulum membrane	Cellular component	-
ARF6	382	ADP-ribosylation factor 6	recycling endosome membrane	Cellular component	21951725
PDE1C	5137	phosphodiesterase 1C, calmodulin-dependent 70kDa	neurotrophin TRK receptor signaling pathway	Biological process	-
HIST1H4D	8360	histone cluster 1, H4d	mitotic cell cycle	Biological process	-
NBEAL2	23218	neurobeachin-like 2	phospholipid binding	Molecular function	-
BTLA	151888	B and T lymphocyte associated	negative regulation of alpha-beta T cell proliferation	Biological process	-
LOC100133495	100133495	HERV-K_11q22.1 provirus ancestral Pol protein [Includes: Reverse transcriptase	DNA recombination	Biological process	-
GPR143	4935	G protein-coupled receptor 143	cytoplasm	Cellular component	10471510
PIAS2	9063	protein inhibitor of activated STAT, 2	negative regulation of sequence-specific DNA binding transcription factor activity	Biological process	20408817
SMC1A	8243	structural maintenance of chromosomes 1A	chromatin binding	Molecular function	11076961
YBX2	51087	Y box binding protein 2	translation regulator activity	Molecular function	-
FGR	2268	FGR proto-oncogene, Src family tyrosine kinase	integrin-mediated signaling pathway	Biological process	-
SLC17A6	57084	solute carrier family 17 (vesicular glutamate transporter), member 6	cell junction	Cellular component	-
ZDHHC15	158866	zinc finger, DHHC-type containing 15	protein-cysteine S-palmitoyltransferase activity	Molecular function	-
ESYT3	83850	extended synaptotagmin-like protein 3	metal ion binding	Molecular function	-
CCZ1B	221960	CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)	vesicle-mediated transport	Biological process	-
ADGRE5	976	adhesion G protein-coupled receptor E5	calcium ion binding	Molecular function	-
OR4F15	390649	olfactory receptor, family 4, subfamily F, member 15	olfactory receptor activity	Molecular function	-
NRP1	8829	neuropilin 1	platelet-derived growth factor receptor signaling pathway	Biological process	21245381
WDR19	57728	WD repeat domain 19	embryonic cranial skeleton morphogenesis	Biological process	-
RHEB	6009	Ras homolog enriched in brain	plasma membrane	Cellular component	-
E2F4	1874	E2F transcription factor 4, p107/p130-binding	multi-ciliated epithelial cell differentiation	Biological process	-
PYCRL	65263	pyrroline-5-carboxylate reductase-like	L-proline biosynthetic process	Biological process	-
DEFB127	140850	defensin, beta 127	protein binding	Molecular function	25416956
ZNF490	57474	zinc finger protein 490	metal ion binding	Molecular function	-
EPN2	22905	epsin 2	lipid binding	Molecular function	-
NPR2	4882	natriuretic peptide receptor 2	intracellular signal transduction	Biological process	-
RNASE13	440163	ribonuclease, RNase A family, 13 (non-active)	ribonuclease activity	Molecular function	-
SYP	6855	synaptophysin	transporter activity	Molecular function	-
CRTC2	200186	CREB regulated transcription coactivator 2	viral process	Biological process	-
VEGFA	7422	vascular endothelial growth factor A	protein homodimerization activity	Molecular function	-
PDCD4	27250	programmed cell death 4 (neoplastic transformation inhibitor)	nucleus	Cellular component	-
PTPRU	10076	protein tyrosine phosphatase, receptor type, U	single organismal cell-cell adhesion	Biological process	16574648
CCL11	6356	chemokine (C-C motif) ligand 11	actin filament organization	Biological process	-
STX7	8417	syntaxin 7	azurophil granule	Cellular component	20170677
MPHOSPH6	10200	M-phase phosphoprotein 6	nuclear exosome (RNase complex)	Cellular component	11719186
TLK2	11011	tousled-like kinase 2	chromosome segregation	Biological process	20705056
ALX1	8092	ALX homeobox 1	cartilage condensation	Biological process	8756334
CYP1A2	1544	cytochrome P450, family 1, subfamily A, polypeptide 2	regulation of gene expression	Biological process	-
MYT1L	23040	myelin transcription factor 1-like	nervous system development	Biological process	-
APOB	338	apolipoprotein B	clathrin-coated endocytic vesicle membrane	Cellular component	-
USP15	9958	ubiquitin specific peptidase 15	cysteine-type endopeptidase activity	Molecular function	21947082
RPL36A	6173	ribosomal protein L36a	ribosome	Cellular component	3542712
ESR1	2099	estrogen receptor 1	intracellular steroid hormone receptor signaling pathway	Biological process	-
TBX3	6926	T-box 3	heart looping	Biological process	-
AMFR	267	autocrine motility factor receptor, E3 ubiquitin protein ligase	integral component of endoplasmic reticulum membrane	Cellular component	11724934
VPS72	6944	vacuolar protein sorting 72 homolog (S. cerevisiae)	nucleus	Cellular component	7702631
ZNF66	7617	zinc finger protein 66	nucleus	Cellular component	-
KLK6	5653	kallikrein-related peptidase 6	extracellular space	Cellular component	16502470
KIF17	57576	kinesin family member 17	microtubule-based movement	Biological process	-
HORMAD1	84072	HORMA domain containing 1	nucleus	Cellular component	-
HSP90AA2P	3324	heat shock protein 90kDa alpha (cytosolic), class A member 2, pseudogene	ATP binding	Molecular function	-
TACR2	6865	tachykinin receptor 2	muscle contraction	Biological process	2173708
SOX11	6664	SRY (sex determining region Y)-box 11	regulation of transforming growth factor beta receptor signaling pathway	Biological process	20624318
CCNE1	898	cyclin E1	positive regulation of transcription, DNA-templated	Biological process	15572661
LRRFIP1	9208	leucine rich repeat (in FLII) interacting protein 1	cellular_component	Cellular component	-
TREX1	11277	three prime repair exonuclease 1	nucleus	Cellular component	-
C12orf49	79794	chromosome 12 open reading frame 49	extracellular region	Cellular component	-
ZSCAN9	7746	zinc finger and SCAN domain containing 9	transcription, DNA-templated	Biological process	-
ZCRB1	85437	zinc finger CCHC-type and RNA binding motif 1	mRNA processing	Biological process	-
HIST2H2BF	440689	histone cluster 2, H2bf	nucleosome assembly	Biological process	-
SIGLEC14	100049587	sialic acid binding Ig-like lectin 14	integral component of membrane	Cellular component	-
CRH	1392	corticotropin releasing hormone	positive regulation of circadian sleep/wake cycle, wakefulness	Biological process	18329818
KRTAP2-3	730755	keratin associated protein 2-3	protein binding	Molecular function	25416956
GMDS	2762	GDP-mannose 4,6-dehydratase	cytoplasm	Cellular component	9525924
SENP2	59343	SUMO1/sentrin/SMT3 specific peptidase 2	protein destabilization	Biological process	22028379
FZD6	8323	frizzled class receptor 6	integral component of plasma membrane	Cellular component	15265686
TOR1B	27348	torsin family 1, member B (torsin B)	protein binding	Molecular function	15147511
AQP5	362	aquaporin 5	water channel activity	Molecular function	12801959
GRXCR2	643226	glutaredoxin, cysteine rich 2	unfolded protein binding	Molecular function	-
LOXL3	84695	lysyl oxidase-like 3	cytoplasm	Cellular component	-
TNNT2	7139	troponin T type 2 (cardiac)	tropomyosin binding	Molecular function	10850966
SLC5A6	8884	solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6	vesicle membrane	Cellular component	-
PDE6G	5148	phosphodiesterase 6G, cGMP-specific, rod, gamma	cGMP binding	Molecular function	-
VPS4A	27183	vacuolar protein sorting 4 homolog A (S. cerevisiae)	cytosol	Cellular component	-
VN1R5	317705	vomeronasal 1 receptor 5 (gene/pseudogene)	pheromone receptor activity	Molecular function	-
ANGPT1	284	angiopoietin 1	activation of transmembrane receptor protein tyrosine kinase activity	Biological process	19424712
FRMD6	122786	FERM domain containing 6	apical junction complex	Cellular component	-
ESR1	2099	estrogen receptor 1	response to estrogen	Biological process	11581164
MCL1	4170	myeloid cell leukemia 1	BH3 domain binding	Molecular function	21036904
PDCD10	11235	programmed cell death 10	protein homodimerization activity	Molecular function	20489202
NKX3-2	579	NK3 homeobox 2	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	-
TFAP2A	7020	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	positive regulation of cell migration	Biological process	-
COMMD1	150684	copper metabolism (Murr1) domain containing 1	endosome membrane	Cellular component	-
IRF2	3660	interferon regulatory factor 2	cytoplasm	Cellular component	-
CPEB3	22849	cytoplasmic polyadenylation element binding protein 3	3'-UTR-mediated mRNA destabilization	Biological process	21336257
PARK2	5071	parkin RBR E3 ubiquitin protein ligase	mitochondrion organization	Biological process	-
RAC1	5879	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	GTP binding	Molecular function	19625648
CMTM2	146225	CKLF-like MARVEL transmembrane domain containing 2	chemotaxis	Biological process	-
RPL10	6134	ribosomal protein L10	translational initiation	Biological process	-
SLC22A1	6580	solute carrier family 22 (organic cation transporter), member 1	acetylcholine transmembrane transporter activity	Molecular function	-
UNC45A	55898	unc-45 homolog A (C. elegans)	Golgi apparatus	Cellular component	-
OR13C5	138799	olfactory receptor, family 13, subfamily C, member 5	G-protein coupled receptor signaling pathway	Biological process	-
ABL1	25	ABL proto-oncogene 1, non-receptor tyrosine kinase	positive regulation of apoptotic process	Biological process	9037071
DCK	1633	deoxycytidine kinase	deoxycytidine kinase activity	Molecular function	12808445
FOXC2	2303	forkhead box C2	somitogenesis	Biological process	-
LDLR	3949	low density lipoprotein receptor	early endosome	Cellular component	15166224
RAF1	5894	Raf-1 proto-oncogene, serine/threonine kinase	innate immune response	Biological process	-
IRX3	79191	iroquois homeobox 3	regulation of transcription, DNA-templated	Biological process	-
DRD1	1812	dopamine receptor D1	protein binding	Molecular function	15569306
DNM2	1785	dynamin 2	endocytosis	Biological process	10101292
U2AF1	7307	U2 small nuclear RNA auxiliary factor 1	positive regulation of protein targeting to mitochondrion	Biological process	24912190
DDB2	1643	damage-specific DNA binding protein 2, 48kDa	nucleotide-excision repair, DNA damage removal	Biological process	-
VGLL2	245806	vestigial-like family member 2	cytoplasm	Cellular component	-
TSPAN6	7105	tetraspanin 6	signal transducer activity	Molecular function	12761501
CNTRL	11064	centriolin	cytosol	Cellular component	-
ATP5C1	509	ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1	mitochondrial proton-transporting ATP synthase complex	Cellular component	12110673
HOXA11	3207	homeobox A11	organ induction	Biological process	-
SESN2	83667	sestrin 2	nucleus	Cellular component	-
UBE2C	11065	ubiquitin-conjugating enzyme E2C	ubiquitin-dependent protein catabolic process	Biological process	18485873
AKAP8L	26993	A kinase (PRKA) anchor protein 8-like	biological_process	Biological process	-
SRSF9	8683	serine/arginine-rich splicing factor 9	negative regulation of mRNA splicing, via spliceosome	Biological process	15009664
NMD3	51068	NMD3 ribosome export adaptor	cytoplasm	Cellular component	12773398
REEP5	7905	receptor accessory protein 5	extracellular exosome	Cellular component	23376485
RGCC	28984	regulator of cell cycle	positive regulation of stress fiber assembly	Biological process	19158077
NME1	4830	NME/NM23 nucleoside diphosphate kinase 1	positive regulation of neuron projection development	Biological process	-
EIF2B5	8893	eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa	translation	Biological process	-
CYP39A1	51302	cytochrome P450, family 39, subfamily A, polypeptide 1	24-hydroxycholesterol 7alpha-hydroxylase activity	Molecular function	-
NEO1	4756	neogenin 1	regulation of transcription, DNA-templated	Biological process	-
GHITM	27069	growth hormone inducible transmembrane protein	extracellular exosome	Cellular component	19056867
FBXL5	26234	F-box and leucine-rich repeat protein 5	protein binding	Molecular function	17532294
FLT4	2324	fms-related tyrosine kinase 4	blood vessel morphogenesis	Biological process	-
RNF20	56254	ring finger protein 20, E3 ubiquitin protein ligase	regulation of transcription, DNA-templated	Biological process	18832071
HAP1	9001	huntingtin-associated protein 1	neurotrophin TRK receptor signaling pathway	Biological process	-
PPP4R2	151987	protein phosphatase 4, regulatory subunit 2	protein binding	Molecular function	16085932
ADGRG7	84873	adhesion G protein-coupled receptor G7	G-protein coupled receptor signaling pathway	Biological process	-
CCM2L	140706	cerebral cavernous malformation 2-like	cardiac muscle tissue growth	Biological process	-
SPSB2	84727	splA/ryanodine receptor domain and SOCS box containing 2	protein binding	Molecular function	15601820
SYT7	9066	synaptotagmin VII	calcium ion-dependent exocytosis of neurotransmitter	Biological process	-
SEPP1	6414	selenoprotein P, plasma, 1	extracellular space	Cellular component	-
ADCY1	107	adenylate cyclase 1 (brain)	plasma membrane	Cellular component	-
ZAN	7455	zonadhesin (gene/pseudogene)	binding of sperm to zona pellucida	Biological process	9126492
IL33	90865	interleukin 33	nucleus	Cellular component	-
GGH	8836	gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)	response to drug	Biological process	-
RIMS1	22999	regulating synaptic membrane exocytosis 1	neurotransmitter secretion	Biological process	-
ADAM10	102	ADAM metallopeptidase domain 10	membrane protein ectodomain proteolysis	Biological process	17965014
DRD1	1812	dopamine receptor D1	positive regulation of release of sequestered calcium ion into cytosol	Biological process	1282671
HRH2	3274	histamine receptor H2	toxin transport	Biological process	-
ZNF528	84436	zinc finger protein 528	regulation of transcription, DNA-templated	Biological process	-
DMTN	2039	dematin actin binding protein	regulation of actin cytoskeleton organization	Biological process	22927433
MRPS30	10884	mitochondrial ribosomal protein S30	mitochondrial translation	Biological process	-
SLC8A1	6546	solute carrier family 8 (sodium/calcium exchanger), member 1	calcium ion transmembrane transport	Biological process	25589784
TNF	7124	tumor necrosis factor	regulation of insulin secretion	Biological process	8383325
PNPLA6	10908	patatin-like phospholipase domain containing 6	lipid catabolic process	Biological process	-
TSTA3	7264	tissue specific transplantation antigen P35B	'de novo' GDP-L-fucose biosynthetic process	Biological process	11698403
CCL16	6360	chemokine (C-C motif) ligand 16	cell-cell signaling	Biological process	9642106
RENBP	5973	renin binding protein	regulation of blood pressure	Biological process	9285790
BBX	56987	bobby sox homolog (Drosophila)	regulation of transcription, DNA-templated	Biological process	-
CRTC1	23373	CREB regulated transcription coactivator 1	cytoplasm	Cellular component	-
ATR	545	ATR serine/threonine kinase	nucleoplasm	Cellular component	-
RPAP3	79657	RNA polymerase II associated protein 3	protein binding	Molecular function	18538670
CORO1B	57175	coronin, actin binding protein, 1B	lamellipodium	Cellular component	22619279
MEF2C	4208	myocyte enhancer factor 2C	heart looping	Biological process	-
STK24	8428	serine/threonine kinase 24	activation of protein kinase activity	Biological process	-
BCAP31	10134	B-cell receptor-associated protein 31	endoplasmic reticulum	Cellular component	-
FGF10	2255	fibroblast growth factor 10	activation of MAPK activity	Biological process	14975937
KIF16B	55614	kinesin family member 16B	endoderm development	Biological process	-
PEX6	5190	peroxisomal biogenesis factor 6	protein binding	Molecular function	16257970
GRHL2	79977	grainyhead-like 2 (Drosophila)	epithelial cell morphogenesis	Biological process	-
CSPG4	1464	chondroitin sulfate proteoglycan 4	positive regulation of peptidyl-tyrosine phosphorylation	Biological process	10587647
GGCX	2677	gamma-glutamyl carboxylase	cellular protein metabolic process	Biological process	-
FGF17	8822	fibroblast growth factor 17	fibroblast growth factor receptor signaling pathway	Biological process	-
FNDC1	84624	fibronectin type III domain containing 1	regulation of protein transport	Biological process	-
DAB2IP	153090	DAB2 interacting protein	phosphatidylinositol 3-kinase regulatory subunit binding	Molecular function	19903888
GSK3B	2932	glycogen synthase kinase 3 beta	organ morphogenesis	Biological process	-
PRMT5	10419	protein arginine methyltransferase 5	protein binding	Molecular function	16087681
LYNX1	66004	Ly6/neurotoxin 1	extracellular exosome	Cellular component	23376485
UBE3C	9690	ubiquitin protein ligase E3C	protein polyubiquitination	Biological process	11278995
TRIM37	4591	tripartite motif containing 37	negative regulation of transcription from RNA polymerase II promoter	Biological process	25470042
RPS6	6194	ribosomal protein S6	mitotic nuclear division	Biological process	-
ARHGAP40	343578	Rho GTPase activating protein 40	GTPase activator activity	Molecular function	-
PICK1	9463	protein interacting with PRKCA 1	protein domain specific binding	Molecular function	-
BCL2L13	23786	BCL2-like 13 (apoptosis facilitator)	integral component of membrane	Cellular component	11262395
TSC2	7249	tuberous sclerosis 2	Fc-epsilon receptor signaling pathway	Biological process	-
SLC10A1	6554	solute carrier family 10 (sodium/bile acid cotransporter), member 1	sodium ion transport	Biological process	-
ZNF491	126069	zinc finger protein 491	transcription, DNA-templated	Biological process	-
RCN1	5954	reticulocalbin 1, EF-hand calcium binding domain	endoplasmic reticulum	Cellular component	-
MLLT6	4302	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6	protein binding	Molecular function	16713569
CYP2J2	1573	cytochrome P450, family 2, subfamily J, polypeptide 2	oxygen binding	Molecular function	-
S100P	6286	S100 calcium binding protein P	RAGE receptor binding	Molecular function	-
NCAPG	64151	non-SMC condensin I complex, subunit G	protein binding	Molecular function	12138188
GSTP1	2950	glutathione S-transferase pi 1	negative regulation of monocyte chemotactic protein-1 production	Biological process	18962899
RFC2	5982	replication factor C (activator 1) 2, 40kDa	DNA strand elongation involved in DNA replication	Biological process	-
MSX1	4487	msh homeobox 1	middle ear morphogenesis	Biological process	-
SLA2	84174	Src-like-adaptor 2	cytoplasm	Cellular component	11696592
NTN1	9423	netrin 1	anterior/posterior axon guidance	Biological process	-
NCBP1	4686	nuclear cap binding protein subunit 1, 80kDa	7-methylguanosine mRNA capping	Biological process	-
EIF4G3	8672	eukaryotic translation initiation factor 4 gamma, 3	translational initiation	Biological process	-
PRTN3	5657	proteinase 3	negative regulation of phagocytosis	Biological process	17712045
FKBP14	55033	FK506 binding protein 14, 22 kDa	cytoplasm	Cellular component	-
AXL	558	AXL receptor tyrosine kinase	natural killer cell differentiation	Biological process	-
EZR	7430	ezrin	cell body	Cellular component	-
PPP2CA	5515	protein phosphatase 2, catalytic subunit, alpha isozyme	membrane	Cellular component	11007961
SIRT1	23411	sirtuin 1	positive regulation of MHC class II biosynthetic process	Biological process	21890893
NUP107	57122	nucleoporin 107kDa	glucose transport	Biological process	-
CYHR1	50626	cysteine/histidine-rich 1	zinc ion binding	Molecular function	-
YES1	7525	YES proto-oncogene 1, Src family tyrosine kinase	blood coagulation	Biological process	-
IFNA6	3443	interferon, alpha 6	humoral immune response	Biological process	-
RASGRF1	5923	Ras protein-specific guanine nucleotide-releasing factor 1	glutamate receptor binding	Molecular function	-
KCNH4	23415	potassium channel, voltage gated eag related subfamily H, member 4	signal transduction by protein phosphorylation	Biological process	-
LEP	3952	leptin	extracellular region	Cellular component	-
TAGLN2	8407	transgelin 2	epithelial cell differentiation	Biological process	21492153
CYP4A22	284541	cytochrome P450, family 4, subfamily A, polypeptide 22	alkane 1-monooxygenase activity	Molecular function	-
S100A10	6281	S100 calcium binding protein A10	positive regulation of GTPase activity	Biological process	23129259
DAB2IP	153090	DAB2 interacting protein	regulation of protein heterodimerization activity	Biological process	18281285
ALKBH2	121642	alkB, alkylation repair homolog 2 (E. coli)	DNA dealkylation involved in DNA repair	Biological process	18775698
VGF	7425	VGF nerve growth factor inducible	transport vesicle	Cellular component	-
PRKAG1	5571	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	mitochondrion organization	Biological process	-
TMEM236	653567	transmembrane protein 236	integral component of membrane	Cellular component	-
HSD17B12	51144	hydroxysteroid (17-beta) dehydrogenase 12	small molecule metabolic process	Biological process	-
AIMP2	7965	aminoacyl tRNA synthetase complex-interacting multifunctional protein 2	Type II pneumocyte differentiation	Biological process	-
AXIN2	8313	axin 2	negative regulation of canonical Wnt signaling pathway	Biological process	11017067
IL4I1	259307	interleukin 4 induced 1	extracellular region	Cellular component	-
ADAMTS9	56999	ADAM metallopeptidase with thrombospondin type 1 motif, 9	vesicle-mediated transport	Biological process	-
IFNA8	3445	interferon, alpha 8	adaptive immune response	Biological process	-
HIPK2	28996	homeodomain interacting protein kinase 2	protein binding	Molecular function	12220523
AATF	26574	apoptosis antagonizing transcription factor	cell adhesion	Biological process	-
MRAS	22808	muscle RAS oncogene homolog	intracellular	Cellular component	10446149
UBE2D4	51619	ubiquitin-conjugating enzyme E2D 4 (putative)	ubiquitin conjugating enzyme activity	Molecular function	21685362
SNCA	6622	synuclein, alpha (non A4 component of amyloid precursor)	negative regulation of serotonin uptake	Biological process	16882008
GPSM3	63940	G-protein signaling modulator 3	cytoplasm	Cellular component	-
NR1D1	9572	nuclear receptor subfamily 1, group D, member 1	cytoplasm	Cellular component	-
GOLT1B	51026	golgi transport 1B	vesicle-mediated transport	Biological process	-
SPAG16	79582	sperm associated antigen 16	axoneme	Cellular component	-
NCAPD2	9918	non-SMC condensin I complex, subunit D2	condensin core heterodimer	Cellular component	10958694
ANK2	287	ankyrin 2, neuronal	enzyme binding	Molecular function	21177872
CRIPAK	285464	cysteine-rich PAK1 inhibitor	regulation of cytoskeleton organization	Biological process	16278681
UCHL1	7345	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)	adult walking behavior	Biological process	-
KLRC1	3821	killer cell lectin-like receptor subfamily C, member 1	integral component of plasma membrane	Cellular component	2007850
SSTR5	6755	somatostatin receptor 5	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	Biological process	7908405
ARID4A	5926	AT rich interactive domain 4A (RBP1-like)	regulation of gene expression by genetic imprinting	Biological process	-
STARD13	90627	StAR-related lipid transfer (START) domain containing 13	lipid particle	Cellular component	-
CTNND1	1500	catenin (cadherin-associated protein), delta 1	protein kinase binding	Molecular function	-
CCDC23	374969	coiled-coil domain containing 23	negative regulation of endothelial cell migration	Biological process	20736312
ACD	65057	adrenocortical dysplasia homolog (mouse)	telomere assembly	Biological process	16880378
MYL6	4637	myosin, light chain 6, alkali, smooth muscle and non-muscle	ephrin receptor signaling pathway	Biological process	-
SLC30A8	169026	solute carrier family 30 (zinc transporter), member 8	Golgi apparatus	Cellular component	15331542
LRWD1	222229	leucine-rich repeats and WD repeat domain containing 1	telomeric heterochromatin	Cellular component	20932478
STK24	8428	serine/threonine kinase 24	execution phase of apoptosis	Biological process	12107159
OXSR1	9943	oxidative stress responsive 1	signal transduction by protein phosphorylation	Biological process	-
ZBTB8A	653121	zinc finger and BTB domain containing 8A	cellular_component	Cellular component	-
BAIAP2L2	80115	BAI1-associated protein 2-like 2	actin filament bundle assembly	Biological process	-
SUV39H1	6839	suppressor of variegation 3-9 homolog 1 (Drosophila)	chromatin silencing at rDNA	Biological process	-
RNF126	55658	ring finger protein 126	epidermal growth factor receptor binding	Molecular function	-
CLK2	1196	CDC-like kinase 2	protein binding	Molecular function	16189514
SYT1	6857	synaptotagmin I	positive regulation of calcium ion-dependent exocytosis	Biological process	-
GJA4	2701	gap junction protein, alpha 4, 37kDa	connexon complex	Cellular component	-
PHOX2B	8929	paired-like homeobox 2b	autonomic nervous system development	Biological process	12640453
SLC8A1	6546	solute carrier family 8 (sodium/calcium exchanger), member 1	protein binding	Molecular function	25589784
ABCG1	9619	ATP-binding cassette, sub-family G (WHITE), member 1	high-density lipoprotein particle remodeling	Biological process	16556852
TMEM55B	90809	transmembrane protein 55B	lysosomal membrane	Cellular component	-
CCNE2	9134	cyclin E2	nucleoplasm	Cellular component	-
PGK1	5230	phosphoglycerate kinase 1	cytosol	Cellular component	-
ITPKA	3706	inositol-trisphosphate 3-kinase A	inositol-1,4,5-trisphosphate 3-kinase activity	Molecular function	-
PWWP2A	114825	PWWP domain containing 2A	protein binding	Molecular function	23752268
SYNJ2	8871	synaptojanin 2	phosphatidylinositol dephosphorylation	Biological process	-
CAT	847	catalase	response to hypoxia	Biological process	-
SYN2	6854	synapsin II	synaptic transmission	Biological process	8964517
GPR37	2861	G protein-coupled receptor 37 (endothelin receptor type B-like)	dopamine biosynthetic process	Biological process	-
SUV39H2	79723	suppressor of variegation 3-9 homolog 2 (Drosophila)	cell differentiation	Biological process	-
CCT6B	10693	chaperonin containing TCP1, subunit 6B (zeta 2)	chaperone-mediated protein complex assembly	Biological process	8812458
GBF1	8729	golgi brefeldin A resistant guanine nucleotide exchange factor 1	mitochondrion	Cellular component	-
RASA2	5922	RAS p21 protein activator 2	cytoplasm	Cellular component	-
STK36	27148	serine/threonine kinase 36	cytoplasm	Cellular component	-
PLK1	5347	polo-like kinase 1	microtubule binding	Molecular function	12939256
PFKFB2	5208	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2	glycolytic process	Biological process	11069105
IKBKG	8517	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	activation of MAPK activity	Biological process	-
COMP	1311	cartilage oligomeric matrix protein	calcium ion binding	Molecular function	10852928
FGFR2	2263	fibroblast growth factor receptor 2	fibroblast growth factor receptor signaling pathway involved in hemopoiesis	Biological process	-
LTBP1	4052	latent transforming growth factor beta binding protein 1	microfibril	Cellular component	12429738
FLOT2	2319	flotillin 2	cell-cell adherens junction	Cellular component	24046456
AOX1	316	aldehyde oxidase 1	electron carrier activity	Molecular function	-
CASC5	57082	cancer susceptibility candidate 5	nucleus	Cellular component	10980622
PLXNA4	91584	plexin A4	plasma membrane	Cellular component	-
EOMES	8320	eomesodermin	cardioblast differentiation	Biological process	-
RP2	6102	retinitis pigmentosa 2 (X-linked recessive)	cytoskeleton organization	Biological process	-
SRSF1	6426	serine/arginine-rich splicing factor 1	nucleus	Cellular component	21630459
FCER1G	2207	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	Fc receptor mediated stimulatory signaling pathway	Biological process	-
AZIN2	113451	antizyme inhibitor 2	spermatogenesis	Biological process	11587527
SOX2	6657	SRY (sex determining region Y)-box 2	response to retinoic acid	Biological process	-
OR8H2	390151	olfactory receptor, family 8, subfamily H, member 2	plasma membrane	Cellular component	-
GLUL	2752	glutamate-ammonia ligase	perikaryon	Cellular component	-
THBS1	7057	thrombospondin 1	negative regulation of plasma membrane long-chain fatty acid transport	Biological process	17416590
GATA3	2625	GATA binding protein 3	transcription regulatory region sequence-specific DNA binding	Molecular function	19723756
SLC5A7	60482	solute carrier family 5 (sodium/choline cotransporter), member 7	acetylcholine biosynthetic process	Biological process	11068039
ACRBP	84519	acrosin binding protein	extracellular region	Cellular component	-
AVPR2	554	arginine vasopressin receptor 2	response to cytokine	Biological process	-
MAP7	9053	microtubule-associated protein 7	protein localization to plasma membrane	Biological process	-
MYBBP1A	10514	MYB binding protein (P160) 1a	cytoplasm	Cellular component	-
GBGT1	26301	globoside alpha-1,3-N-acetylgalactosaminyltransferase 1	integral component of membrane	Cellular component	-
PSMC5	5705	proteasome (prosome, macropain) 26S subunit, ATPase, 5	membrane	Cellular component	19946888
ZFP82	284406	ZFP82 zinc finger protein	nucleus	Cellular component	-
ARL13B	200894	ADP-ribosylation factor-like 13B	small GTPase mediated signal transduction	Biological process	-
RXRA	6256	retinoid X receptor, alpha	nuclear chromatin	Cellular component	18511497
ZBTB26	57684	zinc finger and BTB domain containing 26	RNA polymerase II regulatory region sequence-specific DNA binding	Molecular function	-
HPD	3242	4-hydroxyphenylpyruvate dioxygenase	small molecule metabolic process	Biological process	-
NPM3	10360	nucleophosmin/nucleoplasmin 3	nucleolus	Cellular component	-
CYYR1	116159	cysteine/tyrosine-rich 1	integral component of membrane	Cellular component	-
SHC1	6464	SHC (Src homology 2 domain containing) transforming protein 1	actin cytoskeleton reorganization	Biological process	-
CANX	821	calnexin	post-translational protein modification	Biological process	-
MPRIP	23164	myosin phosphatase Rho interacting protein	actin binding	Molecular function	-
Mar-05	54708	membrane-associated ring finger (C3HC4) 5	regulation of mitochondrial fission	Biological process	16874301
FLNA	2316	filamin A, alpha	protein stabilization	Biological process	18322202
SEC14L2	23541	SEC14-like 2 (S. cerevisiae)	nucleus	Cellular component	11444841
CHMP2B	25978	charged multivesicular body protein 2B	cell separation after cytokinesis	Biological process	20616062
ASPG	374569	asparaginase	phospholipid metabolic process	Biological process	-
RPL22	6146	ribosomal protein L22	RNA binding	Molecular function	8135813
PYGO2	90780	pygopus family PHD finger 2	palate development	Biological process	-
LTA	4049	lymphotoxin alpha	positive regulation of glial cell proliferation	Biological process	-
PAXIP1	22976	PAX interacting (with transcription-activation domain) protein 1	positive regulation of histone acetylation	Biological process	-
NAMPT	10135	nicotinamide phosphoribosyltransferase	circadian regulation of gene expression	Biological process	-
ADRM1	11047	adhesion regulating molecule 1	proteasome binding	Molecular function	18162577
NPC1	4864	Niemann-Pick disease, type C1	integral component of plasma membrane	Cellular component	10821832
C1QBP	708	complement component 1, q subcomponent binding protein	extracellular space	Cellular component	-
DQX1	165545	DEAQ box RNA-dependent ATPase 1	ATP binding	Molecular function	-
KDM7A	80853	lysine (K)-specific demethylase 7A	nucleus	Cellular component	20023638
CNGA2	1260	cyclic nucleotide gated channel alpha 2	response to stimulus	Biological process	-
GLI1	2735	GLI family zinc finger 1	cerebellar cortex morphogenesis	Biological process	-
SHANK2	22941	SH3 and multiple ankyrin repeat domains 2	postsynaptic density	Cellular component	-
PLA2G16	11145	phospholipase A2, group XVI	cytosol	Cellular component	-
USP17L20	100287441	ubiquitin specific peptidase 17-like family member 20	ubiquitin-specific protease activity	Molecular function	-
USP17L12	100287205	ubiquitin specific peptidase 17-like family member 12	nucleus	Cellular component	-
CABIN1	23523	calcineurin binding protein 1	aggresome	Cellular component	-
FSCN1	6624	fascin actin-bundling protein 1	cell motility	Biological process	9571235
KIF5C	3800	kinesin family member 5C	microtubule-based movement	Biological process	-
HTR5A	3361	5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled	G-protein coupled receptor signaling pathway	Biological process	7988681
ADCY10	55811	adenylate cyclase 10 (soluble)	manganese ion binding	Molecular function	-
RPS14	6208	ribosomal protein S14	translation regulator activity	Molecular function	3683397
DMTN	2039	dematin actin binding protein	negative regulation of peptidyl-threonine phosphorylation	Biological process	-
ALPP	250	alkaline phosphatase, placental	dephosphorylation	Biological process	3042787
PPARGC1A	10891	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	cellular response to fatty acid	Biological process	-
IRAK3	11213	interleukin-1 receptor-associated kinase 3	negative regulation of innate immune response	Biological process	12150927
INSR	3643	insulin receptor	exocrine pancreas development	Biological process	-
TEX261	113419	testis expressed 261	integral component of Golgi membrane	Cellular component	-
NUPL2	11097	nucleoporin like 2	glucose transport	Biological process	-
ADK	132	adenosine kinase	adenosine metabolic process	Biological process	-
KLHL41	10324	kelch-like family member 41	sarcomere organization	Biological process	-
MAPK10	5602	mitogen-activated protein kinase 10	toll-like receptor 3 signaling pathway	Biological process	-
PER1	5187	period circadian clock 1	signal transduction	Biological process	-
SIRT2	22933	sirtuin 2	cellular response to epinephrine stimulus	Biological process	-
SH3GLB1	51100	SH3-domain GRB2-like endophilin B1	Golgi membrane	Cellular component	-
SLC17A7	57030	solute carrier family 17 (vesicular glutamate transporter), member 7	synaptic vesicle membrane	Cellular component	-
FLT4	2324	fms-related tyrosine kinase 4	nucleus	Cellular component	-
DUSP26	78986	dual specificity phosphatase 26 (putative)	phosphoserine phosphatase activity	Molecular function	15796912
ZNF385A	25946	zinc finger protein 385A	positive regulation of fat cell differentiation	Biological process	-
LCK	3932	LCK proto-oncogene, Src family tyrosine kinase	neurotrophin TRK receptor signaling pathway	Biological process	-
GAS2L1	10634	growth arrest-specific 2 like 1	microtubule bundle formation	Biological process	12584248
PI4K2B	55300	phosphatidylinositol 4-kinase type 2 beta	small molecule metabolic process	Biological process	-
IFNA8	3445	interferon, alpha 8	B cell proliferation	Biological process	-
NAE1	8883	NEDD8 activating enzyme E1 subunit 1	protein neddylation	Biological process	-
TMEM27	57393	transmembrane protein 27	positive regulation of calcium ion-dependent exocytosis	Biological process	16330323
PCSK4	54760	proprotein convertase subtilisin/kexin type 4	binding of sperm to zona pellucida	Biological process	-
ZBTB14	7541	zinc finger and BTB domain containing 14	protein binding	Molecular function	15629158
OR7G2	390882	olfactory receptor, family 7, subfamily G, member 2	plasma membrane	Cellular component	-
AMBP	259	alpha-1-microglobulin/bikunin precursor	viral process	Biological process	-
OR8H1	219469	olfactory receptor, family 8, subfamily H, member 1	olfactory receptor activity	Molecular function	-
ITPR3	3710	inositol 1,4,5-trisphosphate receptor, type 3	calcium ion transport into cytosol	Biological process	-
TAF11	6882	TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa	protein binding	Molecular function	25416956
SDC1	6382	syndecan 1	protein C-terminus binding	Molecular function	16982797
LAMP1	3916	lysosomal-associated membrane protein 1	positive regulation of natural killer cell degranulation	Biological process	23632890
PIAS1	8554	protein inhibitor of activated STAT, 1	positive regulation of smooth muscle cell differentiation	Biological process	-
CD3E	916	CD3e molecule, epsilon (CD3-TCR complex)	protein binding	Molecular function	11855827
NRXN1	9378	neurexin 1	neuromuscular process controlling balance	Biological process	19822762
INTS6	26512	integrator complex subunit 6	snRNA processing	Biological process	16239144
HECTD1	25831	HECT domain containing E3 ubiquitin protein ligase 1	protein binding	Molecular function	12421765
NUP98	4928	nucleoporin 98kDa	mitotic nuclear envelope disassembly	Biological process	-
DNMT1	1786	DNA (cytosine-5-)-methyltransferase 1	DNA binding	Molecular function	18754681
FGR	2268	FGR proto-oncogene, Src family tyrosine kinase	protein phosphorylation	Biological process	2995972
ATP6V0B	533	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b	vacuolar membrane	Cellular component	-
TGFB2	7042	transforming growth factor, beta 2	positive regulation of epithelial to mesenchymal transition	Biological process	17999987
ZNF688	146542	zinc finger protein 688	cellular_component	Cellular component	-
SDC4	6385	syndecan 4	glycosaminoglycan biosynthetic process	Biological process	-
RIC1	57589	RAB6A GEF complex partner 1	positive regulation of GTPase activity	Biological process	23091056
ZDHHC9	51114	zinc finger, DHHC-type containing 9	palmitoyltransferase complex	Cellular component	16000296
CMTR2	55783	cap methyltransferase 2	nucleus	Cellular component	21310715
MAP2K6	5608	mitogen-activated protein kinase kinase 6	muscle cell differentiation	Biological process	-
PIK3CA	5290	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	positive regulation of protein kinase activity	Biological process	-
PDCD6	10016	programmed cell death 6	extracellular exosome	Cellular component	19056867
ADAM22	53616	ADAM metallopeptidase domain 22	cell adhesion	Biological process	-
LAMA1	284217	laminin, alpha 1	regulation of cell adhesion	Biological process	-
MTSS1	9788	metastasis suppressor 1	cell adhesion	Biological process	12570871
GIMAP5	55340	GTPase, IMAP family member 5	negative regulation of lipid catabolic process	Biological process	-
MIPEP	4285	mitochondrial intermediate peptidase	metalloendopeptidase activity	Molecular function	-
PAX9	5083	paired box 9	negative regulation of transcription, DNA-templated	Biological process	12657635
ITGAV	3685	integrin, alpha V	protein binding	Molecular function	11546839
CYCS	54205	cytochrome c, somatic	response to reactive oxygen species	Biological process	-
SNRPD3	6634	small nuclear ribonucleoprotein D3 polypeptide 18kDa	termination of RNA polymerase II transcription	Biological process	-
FAM129A	116496	family with sequence similarity 129, member A	membrane	Cellular component	19946888
NFKBIL1	4795	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1	negative regulation of lipopolysaccharide-mediated signaling pathway	Biological process	20829348
SPG21	51324	spastic paraplegia 21 (autosomal recessive, Mast syndrome)	nucleoplasm	Cellular component	-
NBN	4683	nibrin	site of double-strand break	Cellular component	15916964
HESX1	8820	HESX homeobox 1	protein C-terminus binding	Molecular function	-
SMARCA4	6597	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	liver development	Biological process	-
PHB2	11331	prohibitin 2	extracellular exosome	Cellular component	23376485
GRIN2B	2904	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	in utero embryonic development	Biological process	-
IFNA5	3442	interferon, alpha 5	T cell activation involved in immune response	Biological process	-
HBS1L	10767	HBS1-like translational GTPase	translation	Biological process	9872408
AGO4	192670	argonaute RISC catalytic component 4	mRNA catabolic process	Biological process	18771919
PLEK	5341	pleckstrin	positive regulation of platelet activation	Biological process	-
UBE2V1	7335	ubiquitin-conjugating enzyme E2 variant 1	ubiquitin protein ligase binding	Molecular function	-
SEH1L	81929	SEH1-like (S. cerevisiae)	post-translational protein modification	Biological process	-
TIMP4	7079	TIMP metallopeptidase inhibitor 4	proteinaceous extracellular matrix	Cellular component	-
STK10	6793	serine/threonine kinase 10	stress-activated protein kinase signaling cascade	Biological process	-
GRB2	2885	growth factor receptor-bound protein 2	signal transduction in response to DNA damage	Biological process	20160708
HDAC2	3066	histone deacetylase 2	positive regulation of receptor biosynthetic process	Biological process	18316616
GRID1	2894	glutamate receptor, ionotropic, delta 1	ionotropic glutamate receptor activity	Molecular function	-
FIGF	2277	c-fos induced growth factor (vascular endothelial growth factor D)	vascular endothelial growth factor receptor 3 binding	Molecular function	-
AKAP6	9472	A kinase (PRKA) anchor protein 6	positive regulation of cell growth	Biological process	16177794
SERINC4	619189	serine incorporator 4	phospholipid biosynthetic process	Biological process	-
NAT8B	51471	N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene)	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor	Molecular function	19011241
PSMD8	5714	proteasome (prosome, macropain) 26S subunit, non-ATPase, 8	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
FEZF1	389549	FEZ family zinc finger 1	RNA polymerase II regulatory region sequence-specific DNA binding	Molecular function	-
SNRPB	6628	small nuclear ribonucleoprotein polypeptides B and B1	positive regulation of defense response to virus by host	Biological process	22020285
DCTPP1	79077	dCTP pyrophosphatase 1	magnesium ion binding	Molecular function	-
RAC1	5879	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	positive regulation of actin filament polymerization	Biological process	-
CLEC4C	170482	C-type lectin domain family 4, member C	carbohydrate binding	Molecular function	-
PPP6R1	22870	protein phosphatase 6, regulatory subunit 1	protein binding	Molecular function	14743216
LAMTOR4	389541	late endosomal/lysosomal adaptor, MAPK and MTOR activator 4	protein localization to lysosome	Biological process	22980980
HPN	3249	hepsin	positive regulation by host of viral transcription	Biological process	15614436
SULT1A3	6818	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3	cytosol	Cellular component	-
UBE2A	7319	ubiquitin-conjugating enzyme E2A	ubiquitin-protein transferase activity	Molecular function	11953320
SMAD9	4093	SMAD family member 9	nucleoplasm	Cellular component	-
CSNK1E	1454	casein kinase 1, epsilon	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
TNFRSF21	27242	tumor necrosis factor receptor superfamily, member 21	myelination	Biological process	-
CCNA2	890	cyclin A2	G2/M transition of mitotic cell cycle	Biological process	-
PEX3	8504	peroxisomal biogenesis factor 3	amino acid transmembrane transporter activity	Molecular function	-
IGKV3D-20	28874	immunoglobulin kappa variable 3D-20	innate immune response	Biological process	-
CLEC3B	7123	C-type lectin domain family 3, member B	cellular response to organic substance	Biological process	7589422
FBXL7	23194	F-box and leucine-rich repeat protein 7	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
TSPO2	222642	translocator protein 2	cholesterol binding	Molecular function	-
KCNJ11	3767	potassium channel, inwardly rectifying subfamily J, member 11	regulation of ion transmembrane transport	Biological process	-
TRAPPC12	51112	trafficking protein particle complex 12	proteolysis	Biological process	-
GDNF	2668	glial cell derived neurotrophic factor	nervous system development	Biological process	8637574
GNG2	54331	guanine nucleotide binding protein (G protein), gamma 2	signal transducer activity	Molecular function	-
ABAT	18	4-aminobutyrate aminotransferase	iron-sulfur cluster binding	Molecular function	-
HNRNPD	3184	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	RNA processing	Biological process	10205060
INO80	54617	INO80 complex subunit	ATPase activity	Molecular function	16298340
LRRFIP1	9208	leucine rich repeat (in FLII) interacting protein 1	protein homodimerization activity	Molecular function	23099021
ISG20L2	81875	interferon stimulated exonuclease gene 20kDa-like 2	ribosome biogenesis	Biological process	-
STRA6	64220	stimulated by retinoic acid 6	nose morphogenesis	Biological process	17273977
ATP10A	57194	ATPase, class V, type 10A	endoplasmic reticulum	Cellular component	21914794
PIGH	5283	phosphatidylinositol glycan anchor biosynthesis, class H	cellular protein modification process	Biological process	8900170
TFAM	7019	transcription factor A, mitochondrial	chromatin remodeling	Biological process	-
ITGA5	3678	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	viral process	Biological process	-
CD36	948	CD36 molecule (thrombospondin receptor)	phagocytic vesicle	Cellular component	-
MYLK	4638	myosin light chain kinase	calmodulin-dependent protein kinase activity	Molecular function	-
OR56A1	120796	olfactory receptor, family 56, subfamily A, member 1	beta-adrenergic receptor activity	Molecular function	-
STIL	6491	SCL/TAL1 interrupting locus	neural tube closure	Biological process	-
DRD4	1815	dopamine receptor D4	drug binding	Molecular function	1319557
CHD5	26038	chromodomain helicase DNA binding protein 5	histone H4 acetylation	Biological process	-
PHF1	5252	PHD finger protein 1	chromatin modification	Biological process	-
LOXL2	4017	lysyl oxidase-like 2	endothelial cell migration	Biological process	21835952
CARTPT	9607	CART prepropeptide	cell-cell signaling	Biological process	8647455
ISL1	3670	ISL LIM homeobox 1	nucleoplasm	Cellular component	-
OR2A42	402317	olfactory receptor, family 2, subfamily A, member 42	G-protein coupled receptor activity	Molecular function	-
GABRR1	2569	gamma-aminobutyric acid (GABA) A receptor, rho 1	integral component of plasma membrane	Cellular component	10779366
SIK1	150094	salt-inducible kinase 1	cytoplasm	Cellular component	-
RWDD3	25950	RWD domain containing 3	protein binding	Molecular function	17956732
TRAFD1	10906	TRAF-type zinc finger domain containing 1	negative regulation of innate immune response	Biological process	-
SCN4B	6330	sodium channel, voltage gated, type IV beta subunit	AV node cell action potential	Biological process	17592081
MTMR3	8897	myotubularin related protein 3	cytoplasm	Cellular component	-
SOAT1	6646	sterol O-acyltransferase 1	membrane	Cellular component	9756919
LIN7A	8825	lin-7 homolog A (C. elegans)	cell-cell junction	Cellular component	-
TMSB10	9168	thymosin beta 10	actin filament organization	Biological process	-
PHF6	84295	PHD finger protein 6	condensed chromosome kinetochore	Cellular component	-
PIGY	84992	phosphatidylinositol glycan anchor biosynthesis, class Y	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex	Cellular component	16162815
FN1	2335	fibronectin 1	extracellular space	Cellular component	20551380
KCNE1	3753	potassium channel, voltage gated subfamily E regulatory beta subunit 1	potassium ion export	Biological process	10400998
TGFB2	7042	transforming growth factor, beta 2	extrinsic apoptotic signaling pathway	Biological process	17217916
ID2	3398	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	metanephros development	Biological process	-
ELMOD1	55531	ELMO/CED-12 domain containing 1	positive regulation of GTPase activity	Biological process	-
LMNTD1	160492	lamin tail domain containing 1	intermediate filament	Cellular component	-
NLRC4	58484	NLR family, CARD domain containing 4	regulation of signal transduction	Biological process	-
COMT	1312	catechol-O-methyltransferase	positive regulation of homocysteine metabolic process	Biological process	-
MYH6	4624	myosin, heavy chain 6, cardiac muscle, alpha	cardiac muscle contraction	Biological process	9884344
HSP90B1	7184	heat shock protein 90kDa beta (Grp94), member 1	protein folding in endoplasmic reticulum	Biological process	22013210
NR4A3	8013	nuclear receptor subfamily 4, group A, member 3	neuromuscular process controlling balance	Biological process	-
ACHE	43	acetylcholinesterase (Yt blood group)	hydrolase activity	Molecular function	1517212
SNX33	257364	sorting nexin 33	mitotic cytokinesis	Biological process	22718350
ERCC2	2068	excision repair cross-complementation group 2	apoptotic process	Biological process	8675009
PIAS1	8554	protein inhibitor of activated STAT, 1	positive regulation of transcription, DNA-templated	Biological process	15572661
SHANK1	50944	SH3 and multiple ankyrin repeat domains 1	plasma membrane	Cellular component	-
DSEL	92126	dermatan sulfate epimerase-like	chondroitin sulfate metabolic process	Biological process	-
SNRPA	6626	small nuclear ribonucleoprotein polypeptide A	cytoplasm	Cellular component	-
PDCL	5082	phosducin-like	regulation of G-protein coupled receptor protein signaling pathway	Biological process	10095058
PPIP5K1	9677	diphosphoinositol pentakisphosphate kinase 1	dephosphorylation	Biological process	-
MYO5A	4644	myosin VA (heavy chain 12, myoxin)	melanosome	Cellular component	-
PPA2	27068	pyrophosphatase (inorganic) 2	protein serine/threonine phosphatase activity	Molecular function	-
GATA3	2625	GATA binding protein 3	transcription regulatory region DNA binding	Molecular function	19735555
ZHX2	22882	zinc fingers and homeoboxes 2	plasma membrane	Cellular component	-
ITPR3	3710	inositol 1,4,5-trisphosphate receptor, type 3	stimulatory C-type lectin receptor signaling pathway	Biological process	-
LRP8	7804	low density lipoprotein receptor-related protein 8, apolipoprotein e receptor	layer formation in cerebral cortex	Biological process	-
OLIG1	116448	oligodendrocyte transcription factor 1	regulation of transcription, DNA-templated	Biological process	-
NDUFA10	4705	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa	respiratory electron transport chain	Biological process	-
OXT	5020	oxytocin/neurophysin I prepropeptide	response to sucrose	Biological process	-
SLC6A14	11254	solute carrier family 6 (amino acid transporter), member 14	vesicle	Cellular component	19190083
CLN8	2055	ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)	negative regulation of transferase activity	Biological process	-
SIN3A	25942	SIN3 transcription regulator family member A	regulation of gene expression, epigenetic	Biological process	-
EHD3	30845	EH-domain containing 3	GTP binding	Molecular function	-
COG2	22796	component of oligomeric golgi complex 2	Golgi membrane	Cellular component	-
CAMK2D	817	calcium/calmodulin-dependent protein kinase II delta	protein serine/threonine kinase activity	Molecular function	22514276
CHD7	55636	chromodomain helicase DNA binding protein 7	palate development	Biological process	15300250
PLCG2	5336	phospholipase C, gamma 2 (phosphatidylinositol-specific)	phosphatidylinositol biosynthetic process	Biological process	11606584
ULK4	54986	unc-51 like kinase 4	protein phosphorylation	Biological process	-
MTERF1	7978	mitochondrial transcription termination factor 1	mitochondrial matrix	Cellular component	-
RFX6	222546	regulatory factor X, 6	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	20148032
HSD17B10	3028	hydroxysteroid (17-beta) dehydrogenase 10	3-hydroxyacyl-CoA dehydrogenase activity	Molecular function	-
RAI1	10743	retinoic acid induced 1	zinc ion binding	Molecular function	-
PRKCD	5580	protein kinase C, delta	regulation of actin cytoskeleton organization	Biological process	22554282
NUP62	23636	nucleoporin 62kDa	viral transcription	Biological process	-
TMOD1	7111	tropomodulin 1	cortical cytoskeleton	Cellular component	-
TRAF2	7186	TNF receptor-associated factor 2	protein heterooligomerization	Biological process	-
SLC22A14	9389	solute carrier family 22, member 14	organic cation transmembrane transporter activity	Molecular function	10072596
SOX9	6662	SRY (sex determining region Y)-box 9	heart valve formation	Biological process	-
HES7	84667	hes family bHLH transcription factor 7	post-anal tail morphogenesis	Biological process	-
LDB3	11155	LIM domain binding 3	perinuclear region of cytoplasm	Cellular component	-
ZSCAN29	146050	zinc finger and SCAN domain containing 29	transcription from RNA polymerase II promoter	Biological process	-
MAGI3	260425	membrane associated guanylate kinase, WW and PDZ domain containing 3	ATP binding	Molecular function	-
TRIM71	131405	tripartite motif containing 71, E3 ubiquitin protein ligase	regulation of gene silencing by miRNA	Biological process	-
SLCO3A1	28232	solute carrier organic anion transporter family, member 3A1	transmembrane transport	Biological process	-
FGFR1	2260	fibroblast growth factor receptor 1	embryonic limb morphogenesis	Biological process	-
HTR2A	3356	5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled	detection of mechanical stimulus involved in sensory perception of pain	Biological process	-
TP63	8626	tumor protein p63	DNA binding	Molecular function	9662346
PSEN2	5664	presenilin 2	Notch signaling pathway	Biological process	-
MAX	4149	MYC associated factor X	transcription cofactor activity	Molecular function	8425218
POLR2H	5437	polymerase (RNA) II (DNA directed) polypeptide H	transcription initiation from RNA polymerase II promoter	Biological process	-
RORC	6097	RAR-related orphan receptor C	T-helper cell differentiation	Biological process	-
FZD4	8322	frizzled class receptor 4	retina vasculature morphogenesis in camera-type eye	Biological process	12172548
RPS7	6201	ribosomal protein S7	protein binding	Molecular function	11823430
SH2D3C	10044	SH2 domain containing 3C	positive regulation of signal transduction	Biological process	10187783
NDST3	9348	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3	integral component of membrane	Cellular component	-
RGS7	6000	regulator of G-protein signaling 7	cytoplasm	Cellular component	-
ACACA	31	acetyl-CoA carboxylase alpha	water-soluble vitamin metabolic process	Biological process	-
EPAS1	2034	endothelial PAS domain protein 1	myoblast fate commitment	Biological process	-
BCL10	8915	B-cell CLL/lymphoma 10	protein kinase B binding	Molecular function	16280327
TINAG	27283	tubulointerstitial nephritis antigen	cysteine-type endopeptidase activity	Molecular function	10652240
ANXA8	653145	annexin A8	negative regulation of serine-type endopeptidase activity	Biological process	2530088
HNRNPU	3192	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	cytoplasmic ribonucleoprotein granule	Cellular component	15121898
API5	8539	apoptosis inhibitor 5	membrane	Cellular component	19946888
FKBP1A	2280	FK506 binding protein 1A, 12kDa	protein peptidyl-prolyl isomerization	Biological process	1696686
P2RX7	5027	purinergic receptor P2X, ligand gated ion channel, 7	neuronal action potential	Biological process	-
ABI2	10152	abl-interactor 2	cell migration	Biological process	12011975
GIPC1	10755	GIPC PDZ domain containing family, member 1	positive regulation of transforming growth factor beta receptor signaling pathway	Biological process	-
UGT3A1	133688	UDP glycosyltransferase 3 family, polypeptide A1	UDP-glycosyltransferase activity	Molecular function	22621930
ACOT7	11332	acyl-CoA thioesterase 7	long-chain fatty-acyl-CoA catabolic process	Biological process	10578051
ADRA1B	147	adrenoceptor alpha 1B	intracellular signal transduction	Biological process	10820200
TUFM	7284	Tu translation elongation factor, mitochondrial	organelle organization	Biological process	-
NKX1-2	390010	NK1 homeobox 2	regulation of transcription, DNA-templated	Biological process	-
IL18	3606	interleukin 18	lipopolysaccharide-mediated signaling pathway	Biological process	21147091
PPARGC1A	10891	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	gluconeogenesis	Biological process	11854298
SLC22A3	6581	solute carrier family 22 (organic cation transporter), member 3	plasma membrane	Cellular component	-
NEDD4L	23327	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase	transmembrane transport	Biological process	-
TRPV3	162514	transient receptor potential cation channel, subfamily V, member 3	integral component of membrane	Cellular component	-
ZP3	7784	zona pellucida glycoprotein 3 (sperm receptor)	extracellular region	Cellular component	-
LMO1	4004	LIM domain only 1 (rhombotin 1)	zinc ion binding	Molecular function	-
SUMO1	7341	small ubiquitin-like modifier 1	protein binding	Molecular function	11112409
CDK2	1017	cyclin-dependent kinase 2	nucleus	Cellular component	10767298
MYOC	4653	myocilin, trabecular meshwork inducible glucocorticoid response	positive regulation of mitochondrial depolarization	Biological process	17516541
DHX40	79665	DEAH (Asp-Glu-Ala-His) box polypeptide 40	RNA processing	Biological process	-
HHATL	57467	hedgehog acyltransferase-like	integral component of membrane	Cellular component	-
CHCHD10	400916	coiled-coil-helix-coiled-coil-helix domain containing 10	mitochondrion	Cellular component	20888800
RAB6A	5870	RAB6A, member RAS oncogene family	myosin V binding	Molecular function	24006491
NEU3	10825	sialidase 3 (membrane sialidase)	oligosaccharide catabolic process	Biological process	10861246
ATG4B	23192	autophagy related 4B, cysteine peptidase	autophagy	Biological process	12446702
ZSCAN20	7579	zinc finger and SCAN domain containing 20	sequence-specific DNA binding transcription factor activity	Molecular function	-
NR4A3	8013	nuclear receptor subfamily 4, group A, member 3	nucleoplasm	Cellular component	-
KEL	3792	Kell blood group, metallo-endopeptidase	protein binding	Molecular function	7737196
SGSM3	27352	small G protein signaling modulator 3	protein binding	Molecular function	17509819
CCBE1	147372	collagen and calcium binding EGF domains 1	protein binding	Molecular function	25416956
RTKN	6242	rhotekin	GTP-Rho binding	Molecular function	10940294
TFR2	7036	transferrin receptor 2	iron ion transport	Biological process	10409623
PPP1CC	5501	protein phosphatase 1, catalytic subunit, gamma isozyme	mitochondrion	Cellular component	17936702
DNAJC13	23317	DnaJ (Hsp40) homolog, subfamily C, member 13	endosome organization	Biological process	24643499
HGSNAT	138050	heparan-alpha-glucosaminide N-acetyltransferase	glycosaminoglycan metabolic process	Biological process	-
ITGB1	3688	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	cell adhesion molecule binding	Molecular function	12869515
MIXL1	83881	Mix paired-like homeobox	cell migration involved in gastrulation	Biological process	-
PLCB4	5332	phospholipase C, beta 4	inositol phosphate metabolic process	Biological process	-
SAMD9	54809	sterile alpha motif domain containing 9	intracellular membrane-bounded organelle	Cellular component	-
PROM1	8842	prominin 1	glomerular parietal epithelial cell differentiation	Biological process	19092120
DUSP2	1844	dual specificity phosphatase 2	protein dephosphorylation	Biological process	8107850
PAWR	5074	PRKC, apoptosis, WT1, regulator	enzyme binding	Molecular function	15671026
HDGFL1	154150	hepatoma derived growth factor-like 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
HRH3	11255	histamine receptor H3	eating behavior	Biological process	-
RBBP4	5928	retinoblastoma binding protein 4	DNA replication	Biological process	-
TNNI3	7137	troponin I type 3 (cardiac)	vasculogenesis	Biological process	-
FNTA	2339	farnesyltransferase, CAAX box, alpha	protein binding	Molecular function	11687658
SGCB	6443	sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)	sarcoglycan complex	Cellular component	-
IKBKE	9641	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	cytoplasm	Cellular component	-
IFITM5	387733	interferon induced transmembrane protein 5	integral component of plasma membrane	Cellular component	24519609
ABCA2	20	ATP-binding cassette, sub-family A (ABC1), member 2	lipid metabolic process	Biological process	11178988
ADRA2B	151	adrenoceptor alpha 2B	cell-cell signaling	Biological process	2164221
FAM65B	9750	family with sequence similarity 65, member B	cytoskeleton	Cellular component	-
RASSF9	9182	Ras association (RalGDS/AF-6) domain family (N-terminal) member 9	transporter activity	Molecular function	9837933
ANXA6	309	annexin A6	protein binding	Molecular function	15576473
RPL28	6158	ribosomal protein L28	cellular protein metabolic process	Biological process	-
RPS16	6217	ribosomal protein S16	protein binding	Molecular function	24725412
NTF3	4908	neurotrophin 3	nerve development	Biological process	-
PAX6	5080	paired box 6	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	-
CHD8	57680	chromodomain helicase DNA binding protein 8	nucleus	Cellular component	18378692
PER2	8864	period circadian clock 2	RNA polymerase binding	Molecular function	-
TGS1	96764	trimethylguanosine synthase 1	small molecule metabolic process	Biological process	-
TAF15	8148	TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa	cytoplasm	Cellular component	19124016
ERVK13-1	100507321	endogenous retrovirus group K13, member 1	viral envelope	Cellular component	-
PSMA6	5687	proteasome (prosome, macropain) subunit, alpha type, 6	mitotic cell cycle	Biological process	-
SLTM	79811	SAFB-like, transcription modulator	nucleotide binding	Molecular function	-
GPR180	160897	G protein-coupled receptor 180	extracellular exosome	Cellular component	23376485
RAB9A	9367	RAB9A, member RAS oncogene family	phagosome-lysosome fusion	Biological process	-
GRM7	2917	glutamate receptor, metabotropic 7	adult behavior	Biological process	-
AGA	175	aspartylglucosaminidase	protein self-association	Molecular function	-
RIT1	6016	Ras-like without CAAX 1	intracellular	Cellular component	-
CDK5	1020	cyclin-dependent kinase 5	cytoplasm	Cellular component	-
TEF	7008	thyrotrophic embryonic factor	sequence-specific DNA binding transcription factor activity	Molecular function	-
GNAI3	2773	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3	synaptic transmission	Biological process	-
WNT4	54361	wingless-type MMTV integration site family, member 4	negative regulation of testicular blood vessel morphogenesis	Biological process	12949260
FGR	2268	FGR proto-oncogene, Src family tyrosine kinase	positive regulation of phosphatidylinositol 3-kinase activity	Biological process	10739672
IFIH1	64135	interferon induced with helicase C domain 1	cytosol	Cellular component	-
JUN	3725	jun proto-oncogene	innate immune response	Biological process	-
RPS27A	6233	ribosomal protein S27a	Notch receptor processing	Biological process	-
AP1G1	164	adaptor-related protein complex 1, gamma 1 subunit	positive regulation of natural killer cell degranulation	Biological process	23632890
TAC1	6863	tachykinin, precursor 1	positive regulation of action potential	Biological process	-
LANCL3	347404	LanC lantibiotic synthetase component C-like 3 (bacterial)	metabolic process	Biological process	-
HMGA1	3159	high mobility group AT-hook 1	senescence-associated heterochromatin focus assembly	Biological process	16901784
SFRP2	6423	secreted frizzled-related protein 2	fibronectin binding	Molecular function	-
ADCYAP1	116	adenylate cyclase activating polypeptide 1 (pituitary)	behavioral fear response	Biological process	-
RBBP8	5932	retinoblastoma binding protein 8	mitotic nuclear division	Biological process	-
RBM4	5936	RNA binding motif protein 4	response to arsenic-containing substance	Biological process	17284590
SLC11A2	4891	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2	cadmium ion binding	Molecular function	25326704
POU2AF1	5450	POU class 2 associating factor 1	transcription coactivator activity	Molecular function	7859290
RNF20	56254	ring finger protein 20, E3 ubiquitin protein ligase	negative regulation of cell migration	Biological process	18832071
ELMOD1	55531	ELMO/CED-12 domain containing 1	GTPase activator activity	Molecular function	17452337
FGF2	2247	fibroblast growth factor 2 (basic)	positive regulation of sprouting angiogenesis	Biological process	16756958
ID2	3398	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	negative regulation of DNA binding	Biological process	-
FABP5	2171	fatty acid binding protein 5 (psoriasis-associated)	cytoplasm	Cellular component	16130169
FAM213B	127281	family with sequence similarity 213, member B	cytoplasm	Cellular component	18006499
CDK2	1017	cyclin-dependent kinase 2	nucleoplasm	Cellular component	-
EIF6	3692	eukaryotic translation initiation factor 6	translation initiation factor activity	Molecular function	-
C11orf73	51501	chromosome 11 open reading frame 73	intracellular	Cellular component	22541429
SMAD3	4088	SMAD family member 3	ubiquitin protein ligase binding	Molecular function	11278251
IVD	3712	isovaleryl-CoA dehydrogenase	mitochondrion	Cellular component	-
SOX17	64321	SRY (sex determining region Y)-box 17	signal transduction involved in regulation of gene expression	Biological process	-
PCBD2	84105	pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2	mitochondrion	Cellular component	-
TNXA	7146	tenascin XA (pseudogene)	molecular_function	Molecular function	-
ESRRB	2103	estrogen-related receptor beta	sequence-specific DNA binding	Molecular function	12654265
S1PR1	1901	sphingosine-1-phosphate receptor 1	G-protein coupled receptor binding	Molecular function	24851274
RARA	5914	retinoic acid receptor, alpha	cell surface	Cellular component	2825025
FAM90A10P	441328	putative protein FAM90A10	zinc ion binding	Molecular function	-
MED16	10025	mediator complex subunit 16	thyroid hormone receptor binding	Molecular function	10198638
RPL27	6155	ribosomal protein L27	membrane	Cellular component	19946888
EXOSC3	51010	exosome component 3	nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription	Biological process	-
HTRA2	27429	HtrA serine peptidase 2	protein binding	Molecular function	10971580
DGAT2	84649	diacylglycerol O-acyltransferase 2	low-density lipoprotein particle clearance	Biological process	-
PLP2	5355	proteolipid protein 2 (colonic epithelium-enriched)	extracellular exosome	Cellular component	23376485
SIN3B	23309	SIN3 transcription regulator family member B	skeletal muscle tissue development	Biological process	-
MPPE1	65258	metallophosphoesterase 1	protein binding	Molecular function	25416956
BAAT	570	bile acid CoA:amino acid N-acyltransferase	carboxylic ester hydrolase activity	Molecular function	-
RTTN	25914	rotatin	centrosome	Cellular component	-
RRAS2	22800	related RAS viral (r-ras) oncogene homolog 2	extracellular exosome	Cellular component	19056867
PPP1R14B	26472	protein phosphatase 1, regulatory (inhibitor) subunit 14B	protein phosphatase inhibitor activity	Molecular function	-
PACS2	23241	phosphofurin acidic cluster sorting protein 2	endoplasmic reticulum lumen	Cellular component	-
TSPY3	728137	testis specific protein, Y-linked 3	cell differentiation	Biological process	-
OR1L1	26737	olfactory receptor, family 1, subfamily L, member 1	plasma membrane	Cellular component	-
LIFR	3977	leukemia inhibitory factor receptor alpha	ciliary neurotrophic factor receptor binding	Molecular function	12707266
POLR2A	5430	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	ubiquitin protein ligase binding	Molecular function	17996703
SMARCD3	6604	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3	cellular lipid metabolic process	Biological process	-
POLR3D	661	polymerase (RNA) III (DNA directed) polypeptide D, 44kDa	nucleoplasm	Cellular component	-
RBMS3	27303	RNA binding motif, single stranded interacting protein 3	nucleotide binding	Molecular function	-
EPS8	2059	epidermal growth factor receptor pathway substrate 8	stereocilium	Cellular component	-
KAT6B	23522	K(lysine) acetyltransferase 6B	nucleosome assembly	Biological process	10497217
DLST	1743	dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)	L-lysine catabolic process to acetyl-CoA via saccharopine	Biological process	-
WNT11	7481	wingless-type MMTV integration site family, member 11	mesonephric duct development	Biological process	9757009
NUDT16	131870	nudix (nucleoside diphosphate linked moiety X)-type motif 16	metalloexopeptidase activity	Molecular function	21337011
OARD1	221443	O-acyl-ADP-ribose deacylase 1	protein binding	Molecular function	23481255
SFRP5	6425	secreted frizzled-related protein 5	Wnt-activated receptor activity	Molecular function	-
DHCR24	1718	24-dehydrocholesterol reductase	apoptotic process	Biological process	11007892
TLR7	51284	toll-like receptor 7	toll-like receptor signaling pathway	Biological process	-
MAP2K1	5604	mitogen-activated protein kinase kinase 1	peptidyl-tyrosine phosphorylation	Biological process	-
BLOC1S5	63915	biogenesis of lysosomal organelles complex-1, subunit 5, muted	endosome to melanosome transport	Biological process	17182842
EXOSC10	5394	exosome component 10	CUT catabolic process	Biological process	19056938
PKHD1	5314	polycystic kidney and hepatic disease 1 (autosomal recessive)	regulation of centrosome duplication	Biological process	20554582
SHMT2	6472	serine hydroxymethyltransferase 2 (mitochondrial)	mitochondrial intermembrane space	Cellular component	-
ATP6V1G1	9550	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1	transmembrane transport	Biological process	-
NABP2	79035	nucleic acid binding protein 2	SOSS complex	Cellular component	18449195
CCNG1	900	cyclin G1	protein binding	Molecular function	21516116
SFN	2810	stratifin	extracellular space	Cellular component	8515476
MDM4	4194	MDM4, p53 regulator	negative regulation of cell cycle arrest	Biological process	-
TIMP2	7077	TIMP metallopeptidase inhibitor 2	response to drug	Biological process	-
CASP9	842	caspase 9, apoptosis-related cysteine peptidase	programmed cell death	Biological process	-
HES1	3280	hes family bHLH transcription factor 1	transcription from RNA polymerase II promoter	Biological process	-
TROVE2	6738	TROVE domain family, member 2	smoothened signaling pathway	Biological process	-
SIX4	51804	SIX homeobox 4	negative regulation of neuron apoptotic process	Biological process	-
LOC81691	81691	exonuclease NEF-sp	nucleotide binding	Molecular function	-
TRAK2	66008	trafficking protein, kinesin binding 2	protein O-linked glycosylation	Biological process	-
PCNP	57092	PEST proteolytic signal containing nuclear protein	protein ubiquitination	Biological process	14741369
CABP4	57010	calcium binding protein 4	retinal cone cell development	Biological process	-
KCNQ2	3785	potassium channel, voltage gated KQT-like subfamily Q, member 2	potassium ion transport	Biological process	9677360
PHF8	23133	PHD finger protein 8	transcription, DNA-templated	Biological process	-
ADCYAP1	116	adenylate cyclase activating polypeptide 1 (pituitary)	positive regulation of interleukin-6 production	Biological process	-
HAO1	54363	hydroxyacid oxidase (glycolate oxidase) 1	fatty acid alpha-oxidation	Biological process	18215067
CREB1	1385	cAMP responsive element binding protein 1	Notch signaling pathway	Biological process	-
AGBL5	60509	ATP/GTP binding protein-like 5	cytoplasm	Cellular component	-
TICAM1	148022	toll-like receptor adaptor molecule 1	positive regulation of B cell proliferation	Biological process	-
RUNX2	860	runt-related transcription factor 2	positive regulation of osteoblast differentiation	Biological process	-
ERF	2077	Ets2 repressor factor	ectodermal cell differentiation	Biological process	-
GNRHR2	114814	gonadotropin-releasing hormone (type 2) receptor 2, pseudogene	peptide binding	Molecular function	-
CBLB	868	Cbl proto-oncogene B, E3 ubiquitin protein ligase	negative regulation of T cell receptor signaling pathway	Biological process	-
RB1CC1	9821	RB1-inducible coiled-coil 1	transcription, DNA-templated	Biological process	-
CUX2	23316	cut-like homeobox 2	short-term memory	Biological process	-
TAPBP	6892	TAP binding protein (tapasin)	TAP2 binding	Molecular function	12788224
GZMA	3001	granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)	protein homodimerization activity	Molecular function	12819770
PABPC1	26986	poly(A) binding protein, cytoplasmic 1	translation activator activity	Molecular function	11997512
GPLD1	2822	glycosylphosphatidylinositol specific phospholipase D1	cellular response to cholesterol	Biological process	17761367
XIRP1	165904	xin actin-binding repeat containing 1	actin binding	Molecular function	-
NRAS	4893	neuroblastoma RAS viral (v-ras) oncogene homolog	Golgi apparatus	Cellular component	21968647
RABEP1	9135	rabaptin, RAB GTPase binding effector protein 1	endosome	Cellular component	20682791
PSMD6	9861	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	negative regulation of canonical Wnt signaling pathway	Biological process	-
SIT1	27240	signaling threshold regulating transmembrane adaptor 1	kinase binding	Molecular function	10209036
CIAO1	9391	cytosolic iron-sulfur assembly component 1	chromosome segregation	Biological process	-
GALP	85569	galanin-like peptide	biological_process	Biological process	-
CD40	958	CD40 molecule, TNF receptor superfamily member 5	positive regulation of transcription from RNA polymerase II promoter	Biological process	21410936
NCK1	4690	NCK adaptor protein 1	signal complex assembly	Biological process	12110186
DLX5	1749	distal-less homeobox 5	transcription regulatory region DNA binding	Molecular function	19497851
CEP162	22832	centrosomal protein 162kDa	centrosome	Cellular component	-
DVL1	1855	dishevelled segment polarity protein 1	molecular_function	Molecular function	-
CYP1B1	1545	cytochrome P450, family 1, subfamily B, polypeptide 1	sterol metabolic process	Biological process	-
PSMF1	9491	proteasome (prosome, macropain) inhibitor subunit 1 (PI31)	apoptotic process	Biological process	-
RAB40AL	282808	RAB40A, member RAS oncogene family-like	Rab protein signal transduction	Biological process	-
S100A12	6283	S100 calcium binding protein A12	neutrophil chemotaxis	Biological process	18443896
SIPA1	6494	signal-induced proliferation-associated 1	perinuclear region of cytoplasm	Cellular component	-
ANKFY1	51479	ankyrin repeat and FYVE domain containing 1	membrane	Cellular component	10940552
CD1D	912	CD1d molecule	cell adhesion molecule binding	Molecular function	19124746
PLCB1	23236	phospholipase C, beta 1 (phosphoinositide-specific)	positive regulation of G1/S transition of mitotic cell cycle	Biological process	-
ATIC	471	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	nucleobase-containing compound metabolic process	Biological process	8567683
FN1	2335	fibronectin 1	basal lamina	Cellular component	-
CPE	1363	carboxypeptidase E	metabolic process	Biological process	7663508
MTERF1	7978	mitochondrial transcription termination factor 1	gene expression	Biological process	-
ZC3H12A	80149	zinc finger CCCH-type containing 12A	protein binding	Molecular function	16189514
UBE2H	7328	ubiquitin-conjugating enzyme E2H	ubiquitin protein ligase activity	Molecular function	-
LFNG	3955	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	metabolic process	Biological process	-
ATP5J2	9551	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2	mitochondrial proton-transporting ATP synthase complex	Cellular component	11959398
MMP11	4320	matrix metallopeptidase 11	collagen fibril organization	Biological process	-
USP13	8975	ubiquitin specific peptidase 13 (isopeptidase T-3)	ubiquitin-specific protease activity	Molecular function	21811243
EIF4A2	1974	eukaryotic translation initiation factor 4A2	ATP-dependent RNA helicase activity	Molecular function	-
KRT71	112802	keratin 71, type II	intermediate filament organization	Biological process	22592156
CPS1	1373	carbamoyl-phosphate synthase 1, mitochondrial	response to lipopolysaccharide	Biological process	15897806
SORBS3	10174	sorbin and SH3 domain containing 3	transcription factor binding	Molecular function	-
ROCK2	9475	Rho-associated, coiled-coil containing protein kinase 2	cytoplasmic ribonucleoprotein granule	Cellular component	15121898
OR4C5	79346	olfactory receptor, family 4, subfamily C, member 5 (gene/pseudogene)	integral component of membrane	Cellular component	-
Sep-09	10801	septin 9	metabolic process	Biological process	10339604
FKBP4	2288	FK506 binding protein 4, 59kDa	neuronal cell body	Cellular component	-
RAB37	326624	RAB37, member RAS oncogene family	secretory granule membrane	Cellular component	-
TBPL1	9519	TBP-like 1	regulation of transcription, DNA-templated	Biological process	-
CEP85	64793	centrosomal protein 85kDa	spindle pole	Cellular component	21399614
SMO	6608	smoothened, frizzled class receptor	renal system development	Biological process	17850284
PEMT	10400	phosphatidylethanolamine N-methyltransferase	endoplasmic reticulum membrane	Cellular component	-
CFTR	1080	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	endoplasmic reticulum Sec complex	Cellular component	9792704
ZNF534	147658	zinc finger protein 534	DNA binding	Molecular function	-
NPC1	4864	Niemann-Pick disease, type C1	lysosome	Cellular component	-
CALHM1	255022	calcium homeostasis modulator 1	identical protein binding	Molecular function	18585350
CDC25C	995	cell division cycle 25C	DNA replication	Biological process	-
PKD1	5310	polycystic kidney disease 1 (autosomal dominant)	mesonephric duct development	Biological process	11891195
TAB1	10454	TGF-beta activated kinase 1/MAP3K7 binding protein 1	mitogen-activated protein kinase p38 binding	Molecular function	-
ARNTL	406	aryl hydrocarbon receptor nuclear translocator-like	chromatoid body	Cellular component	-
MRPL37	51253	mitochondrial ribosomal protein L37	mitochondrial translational termination	Biological process	-
STUB1	10273	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase	positive regulation of protein ubiquitination	Biological process	11146632
JPH3	57338	junctophilin 3	calcium-release channel activity	Molecular function	-
PAK1	5058	p21 protein (Cdc42/Rac)-activated kinase 1	small GTPase mediated signal transduction	Biological process	-
CASP8	841	caspase 8, apoptosis-related cysteine peptidase	natural killer cell activation	Biological process	18309324
PIGS	94005	phosphatidylinositol glycan anchor biosynthesis, class S	endoplasmic reticulum membrane	Cellular component	-
HNF4A	3172	hepatocyte nuclear factor 4, alpha	phospholipid homeostasis	Biological process	-
ABCD1	215	ATP-binding cassette, sub-family D (ALD), member 1	cytosol	Cellular component	-
C3AR1	719	complement component 3a receptor 1	complement receptor mediated signaling pathway	Biological process	8765043
YWHAB	7529	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta	cytoplasmic vesicle membrane	Cellular component	-
CACNA2D3	55799	calcium channel, voltage-dependent, alpha 2/delta subunit 3	regulation of calcium ion transport	Biological process	-
TLR2	7097	toll-like receptor 2	positive regulation of nitric oxide biosynthetic process	Biological process	-
NDUFS5	4725	NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase)	mitochondrion	Cellular component	16826196
MUSK	4593	muscle, skeletal, receptor tyrosine kinase	cell differentiation	Biological process	-
MOCOS	55034	molybdenum cofactor sulfurase	lyase activity	Molecular function	-
C1QTNF7	114905	C1q and tumor necrosis factor related protein 7	collagen trimer	Cellular component	-
ERBB4	2066	erb-b2 receptor tyrosine kinase 4	signal transduction	Biological process	10572067
LHX1	3975	LIM homeobox 1	sequence-specific DNA binding transcription factor activity	Molecular function	-
IL21	59067	interleukin 21	interleukin-2 receptor binding	Molecular function	12504082
TRIM24	8805	tripartite motif containing 24	protein catabolic process	Biological process	19556538
NTRK3	4916	neurotrophic tyrosine kinase, receptor, type 3	positive regulation of cell migration	Biological process	23027130
PARK7	11315	parkinson protein 7	protein homodimerization activity	Molecular function	18711745
CSTF2	1478	cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa	poly(A) RNA binding	Molecular function	22658674
SPATA24	202051	spermatogenesis associated 24	cytoplasm	Cellular component	-
DENND5A	23258	DENN/MADD domain containing 5A	trans-Golgi network	Cellular component	19619496
KIF14	9928	kinesin family member 14	negative regulation of apoptotic process	Biological process	24784001
CD4	920	CD4 molecule	positive regulation of protein kinase activity	Biological process	2118992
RIPK1	8737	receptor (TNFRSF)-interacting serine-threonine kinase 1	negative regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	17047155
ARID3C	138715	AT rich interactive domain 3C (BRIGHT-like)	chromatin binding	Molecular function	-
ECM2	1842	extracellular matrix protein 2, female organ and adipocyte specific	positive regulation of cell-substrate adhesion	Biological process	-
TSSK3	81629	testis-specific serine kinase 3	cytoplasm	Cellular component	-
C11orf30	56946	chromosome 11 open reading frame 30	regulation of transcription, DNA-templated	Biological process	-
KCTD13	253980	potassium channel tetramerization domain containing 13	stress fiber assembly	Biological process	19782033
SOD1	6647	superoxide dismutase 1, soluble	heart contraction	Biological process	9539776
DNAL4	10126	dynein, axonemal, light chain 4	cytoplasm	Cellular component	-
AURKC	6795	aurora kinase C	spindle pole centrosome	Cellular component	-
NPFFR2	10886	neuropeptide FF receptor 2	cellular response to hormone stimulus	Biological process	-
GFI1	2672	growth factor independent 1 transcription repressor	regulation of transcription involved in G1/S transition of mitotic cell cycle	Biological process	8441411
GPN3	51184	GPN-loop GTPase 3	GTP binding	Molecular function	-
GDF15	9518	growth differentiation factor 15	growth factor activity	Molecular function	-
CP	1356	ceruloplasmin (ferroxidase)	extracellular exosome	Cellular component	19056867
SLC9A3R2	9351	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2	phosphatase binding	Molecular function	16456542
CBY1	25776	chibby homolog 1 (Drosophila)	trans-Golgi network	Cellular component	15194699
OR5J2	282775	olfactory receptor, family 5, subfamily J, member 2	plasma membrane	Cellular component	-
NMD3	51068	NMD3 ribosome export adaptor	nucleus	Cellular component	-
RPS24	6229	ribosomal protein S24	cytoplasm	Cellular component	-
OR4E2	26686	olfactory receptor, family 4, subfamily E, member 2	detection of chemical stimulus involved in sensory perception	Biological process	-
ENG	2022	endoglin	regulation of cell adhesion	Biological process	11382917
TBC1D20	128637	TBC1 domain family, member 20	endoplasmic reticulum membrane	Cellular component	17684057
DHFRP1	573971	dihydrofolate reductase pseudogene 1	mitotic cell cycle	Biological process	-
SNAP23	8773	synaptosomal-associated protein, 23kDa	membrane fusion	Biological process	10839363
ABCB1	5243	ATP-binding cassette, sub-family B (MDR/TAP), member 1	xenobiotic-transporting ATPase activity	Molecular function	-
RIPK2	8767	receptor-interacting serine-threonine kinase 2	positive regulation of interleukin-6 production	Biological process	-
S100A7A	338324	S100 calcium binding protein A7A	cytoplasm	Cellular component	-
IGFBP5	3488	insulin-like growth factor binding protein 5	protein binding	Molecular function	15700281
TRPM4	54795	transient receptor potential cation channel, subfamily M, member 4	dendritic cell chemotaxis	Biological process	-
CYP8B1	1582	cytochrome P450, family 8, subfamily B, polypeptide 1	7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity	Molecular function	-
SERPINH1	871	serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)	poly(A) RNA binding	Molecular function	22658674
SNRPB	6628	small nuclear ribonucleoprotein polypeptides B and B1	U7 snRNP	Cellular component	11574479
CTGF	1490	connective tissue growth factor	lung development	Biological process	-
OPHN1	4983	oligophrenin 1	synaptic vesicle endocytosis	Biological process	-
PPARGC1B	133522	peroxisome proliferator-activated receptor gamma, coactivator 1 beta	RNA binding	Molecular function	11854298
NKX2-1	7080	NK2 homeobox 1	forebrain dorsal/ventral pattern formation	Biological process	-
MC1R	4157	melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)	positive regulation of protein kinase A signaling	Biological process	18292087
ADRA1D	146	adrenoceptor alpha 1D	G-protein coupled receptor signaling pathway	Biological process	1656955
CIB1	10519	calcium and integrin binding 1 (calmyrin)	positive regulation of substrate adhesion-dependent cell spreading	Biological process	11756406
ABCC8	6833	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	potassium ion transmembrane transporter activity	Molecular function	7502040
IL6	3569	interleukin 6	defense response to Gram-positive bacterium	Biological process	16034137
CD160	11126	CD160 molecule	protein binding	Molecular function	25416956
DRAM1	55332	DNA-damage regulated autophagy modulator 1	lysosome	Cellular component	19895784
MYO3A	53904	myosin IIIA	stereocilium bundle tip	Cellular component	-
PSMD2	5708	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	regulation of apoptotic process	Biological process	-
CD226	10666	CD226 molecule	membrane raft	Cellular component	16831868
CDC42EP4	23580	CDC42 effector protein (Rho GTPase binding) 4	microtubule cytoskeleton	Cellular component	-
SLC11A1	6556	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1	late endosome membrane	Cellular component	-
ALKBH5	54890	AlkB family member 5, RNA demethylase	response to hypoxia	Biological process	21264265
CD276	80381	CD276 molecule	negative regulation of interferon-gamma biosynthetic process	Biological process	-
YIPF4	84272	Yip1 domain family, member 4	endoplasmic reticulum	Cellular component	-
NEIL2	252969	nei endonuclease VIII-like 2 (E. coli)	base-excision repair	Biological process	-
LIFR	3977	leukemia inhibitory factor receptor alpha	leukemia inhibitory factor receptor activity	Molecular function	12643274
CXXC1	30827	CXXC finger protein 1	unmethylated CpG binding	Molecular function	10688657
ADD1	118	adducin 1 (alpha)	nucleus	Cellular component	16289097
IL1R2	7850	interleukin 1 receptor, type II	cytokine-mediated signaling pathway	Biological process	10191101
ARPP19	10776	cAMP-regulated phosphoprotein, 19kDa	cell division	Biological process	-
ENPP1	5167	ectonucleotide pyrophosphatase/phosphodiesterase 1	3'-phosphoadenosine 5'-phosphosulfate metabolic process	Biological process	7830796
ALDH1A1	216	aldehyde dehydrogenase 1 family, member A1	extracellular exosome	Cellular component	19056867
CLPS	1208	colipase, pancreatic	lipid catabolic process	Biological process	-
SPNS1	83985	spinster homolog 1 (Drosophila)	transmembrane transport	Biological process	-
EDN1	1906	endothelin 1	regulation of pH	Biological process	-
ZBTB8A	653121	zinc finger and BTB domain containing 8A	molecular_function	Molecular function	-
SDHAF2	54949	succinate dehydrogenase complex assembly factor 2	protein binding	Molecular function	19628817
EPB41L3	23136	erythrocyte membrane protein band 4.1-like 3	cortical cytoskeleton organization	Biological process	21966409
ILVBL	10994	ilvB (bacterial acetolactate synthase)-like	biological_process	Biological process	-
SLC4A1	6521	solute carrier family 4 (anion exchanger), member 1 (Diego blood group)	plasma membrane	Cellular component	-
KIAA0586	9786	KIAA0586	ciliary basal body	Cellular component	24421332
ZNF395	55893	zinc finger protein 395	regulation of transcription, DNA-templated	Biological process	14625278
DIRC2	84925	disrupted in renal carcinoma 2	lysosomal membrane	Cellular component	-
RMI1	80010	RecQ mediated genome instability 1	protein binding	Molecular function	15775963
SRPK1	6732	SRSF protein kinase 1	plasma membrane	Cellular component	-
HSF1	3297	heat shock transcription factor 1	nucleoplasm	Cellular component	-
HNRNPDL	9987	heterogeneous nuclear ribonucleoprotein D-like	RNA processing	Biological process	9538234
TPO	7173	thyroid peroxidase	oxidation-reduction process	Biological process	-
SEMA3A	10371	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	nerve development	Biological process	-
RBM5	10181	RNA binding motif protein 5	mRNA splicing, via spliceosome	Biological process	-
NPSR1	387129	neuropeptide S receptor 1	integral component of plasma membrane	Cellular component	15947423
CYR61	3491	cysteine-rich, angiogenic inducer, 61	negative regulation of apoptotic process	Biological process	-
GPX4	2879	glutathione peroxidase 4	phospholipid-hydroperoxide glutathione peroxidase activity	Molecular function	-
PADI4	23569	peptidyl arginine deiminase, type IV	innate immune response	Biological process	-
ALG2	85365	ALG2, alpha-1,3/1,6-mannosyltransferase	protein binding	Molecular function	11883939
RNF7	9616	ring finger protein 7	Cul3-RING ubiquitin ligase complex	Cellular component	-
PCDHGA3	56112	protocadherin gamma subfamily A, 3	homophilic cell adhesion via plasma membrane adhesion molecules	Biological process	-
GNAI2	2771	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	metal ion binding	Molecular function	-
OXTR	5021	oxytocin receptor	cell-cell adherens junction	Cellular component	-
SCRIB	23513	scribbled planar cell polarity protein	postsynaptic membrane	Cellular component	15182672
DERL2	51009	derlin 2	late endosome	Cellular component	-
POLR2I	5438	polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa	gene expression	Biological process	-
CNTNAP1	8506	contactin associated protein 1	intracellular	Cellular component	-
HRH3	11255	histamine receptor H3	memory	Biological process	-
ACSM1	116285	acyl-CoA synthetase medium-chain family member 1	GTP binding	Molecular function	-
EED	8726	embryonic ectoderm development	nucleus	Cellular component	9584199
PRPF4	9128	pre-mRNA processing factor 4	mRNA splicing, via spliceosome	Biological process	-
MIB1	57534	mindbomb E3 ubiquitin protein ligase 1	positive regulation of endocytosis	Biological process	-
ACTL7A	10881	actin-like 7A	cytoskeleton	Cellular component	-
SRSF1	6426	serine/arginine-rich splicing factor 1	mRNA binding	Molecular function	21984414
ZBTB7C	201501	zinc finger and BTB domain containing 7C	nucleic acid binding	Molecular function	-
HSPD1	3329	heat shock 60kDa protein 1 (chaperonin)	positive regulation of interferon-alpha production	Biological process	17164250
FOXE1	2304	forkhead box E1	anatomical structure morphogenesis	Biological process	9169137
BAD	572	BCL2-associated agonist of cell death	extrinsic apoptotic signaling pathway	Biological process	18852119
TCF21	6943	transcription factor 21	protein dimerization activity	Molecular function	-
UGT1A10	54575	UDP glucuronosyltransferase 1 family, polypeptide A10	negative regulation of fatty acid metabolic process	Biological process	20610558
HDAC1	3065	histone deacetylase 1	NAD-dependent histone deacetylase activity (H3-K9 specific)	Molecular function	-
HMGA1	3159	high mobility group AT-hook 1	enzyme binding	Molecular function	16157300
JAK1	3716	Janus kinase 1	protein phosphatase binding	Molecular function	11909529
KRT8	3856	keratin 8, type II	response to hydrostatic pressure	Biological process	-
LY6G5C	80741	lymphocyte antigen 6 complex, locus G5C	extracellular region	Cellular component	-
GBX2	2637	gastrulation brain homeobox 2	inner ear morphogenesis	Biological process	-
TESC	54997	tescalcin	plasma membrane	Cellular component	18321853
DAO	1610	D-amino-acid oxidase	protein dimerization activity	Molecular function	16616139
HTRA4	203100	HtrA serine peptidase 4	serine-type endopeptidase activity	Molecular function	-
SLC5A4	6527	solute carrier family 5 (glucose activated ion channel), member 4	integral component of membrane	Cellular component	-
MYO1C	4641	myosin IC	receptor binding	Molecular function	21402783
NXPH4	11247	neurexophilin 4	extracellular region	Cellular component	-
RAB3A	5864	RAB3A, member RAS oncogene family	protein localization to plasma membrane	Biological process	-
ATP1A2	477	ATPase, Na+/K+ transporting, alpha 2 polypeptide	negative regulation of calcium:sodium antiporter activity	Biological process	-
ASPH	444	aspartate beta-hydroxylase	regulation of cell communication by electrical coupling	Biological process	22123818
OPRL1	4987	opiate receptor-like 1	sensory perception of pain	Biological process	-
LONP2	83752	lon peptidase 2, peroxisomal	receptor binding	Molecular function	20178365
PPIA	5478	peptidylprolyl isomerase A (cyclophilin A)	regulation of viral genome replication	Biological process	7590732
VTN	7448	vitronectin	negative regulation of endopeptidase activity	Biological process	1695900
MYL10	93408	myosin, light chain 10, regulatory	mitochondrion	Cellular component	-
TM6SF1	53346	transmembrane 6 superfamily member 1	biological_process	Biological process	-
UGT1A9	54600	UDP glucuronosyltransferase 1 family, polypeptide A9	retinoic acid binding	Molecular function	20308471
RORC	6097	RAR-related orphan receptor C	Peyer's patch development	Biological process	-
HNRNPA3	220988	heterogeneous nuclear ribonucleoprotein A3	nucleotide binding	Molecular function	-
SNCA	6622	synuclein, alpha (non A4 component of amyloid precursor)	dopamine uptake involved in synaptic transmission	Biological process	21320589
ADGRG6	57211	adhesion G protein-coupled receptor G6	G-protein coupled receptor activity	Molecular function	-
RAB3C	115827	RAB3C, member RAS oncogene family	Rab protein signal transduction	Biological process	-
NLRP4	147945	NLR family, pyrin domain containing 4	extracellular exosome	Cellular component	23376485
OR56B2P	390073	olfactory receptor, family 56, subfamily B, member 2 pseudogene	plasma membrane	Cellular component	-
CCDC12	151903	coiled-coil domain containing 12	protein binding	Molecular function	22365833
RPS6	6194	ribosomal protein S6	polysome	Cellular component	-
SIAH1	6477	siah E3 ubiquitin protein ligase 1	apoptotic process	Biological process	9403064
CHRNB4	1143	cholinergic receptor, nicotinic, beta 4 (neuronal)	action potential	Biological process	-
C6orf15	29113	chromosome 6 open reading frame 15	collagen V binding	Molecular function	-
PPHLN1	51535	periphilin 1	cytoplasm	Cellular component	-
PRKAB1	5564	protein kinase, AMP-activated, beta 1 non-catalytic subunit	positive regulation of gene expression	Biological process	17028174
TIGAR	57103	TP53 induced glycolysis regulatory phosphatase	transcription initiation from RNA polymerase II promoter	Biological process	-
MORF4L1	10933	mortality factor 4 like 1	transcription, DNA-templated	Biological process	-
EPHA7	2045	EPH receptor A7	regulation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	-
FKTN	2218	fukutin	endoplasmic reticulum	Cellular component	18808525
HIST2H2AB	317772	histone cluster 2, H2ab	nucleus	Cellular component	21630459
RAB34	83871	RAB34, member RAS oncogene family	protein binding	Molecular function	16138900
ADCY2	108	adenylate cyclase 2 (brain)	intracellular	Cellular component	-
TRPV4	59341	transient receptor potential cation channel, subfamily V, member 4	adherens junction	Cellular component	-
CD86	942	CD86 molecule	positive regulation of interleukin-2 biosynthetic process	Biological process	9915850
DLD	1738	dihydrolipoamide dehydrogenase	branched-chain amino acid catabolic process	Biological process	-
DGKI	9162	diacylglycerol kinase, iota	protein kinase C-activating G-protein coupled receptor signaling pathway	Biological process	-
TSPYL5	85453	TSPY-like 5	protein binding	Molecular function	21170034
ERBB3	2065	erb-b2 receptor tyrosine kinase 3	apical plasma membrane	Cellular component	-
PAK3	5063	p21 protein (Cdc42/Rac)-activated kinase 3	stress-activated protein kinase signaling cascade	Biological process	-
DNMT3B	1789	DNA (cytosine-5-)-methyltransferase 3 beta	nucleoplasm	Cellular component	-
HLA-DQB2	3120	major histocompatibility complex, class II, DQ beta 2	transport vesicle membrane	Cellular component	-
THSD4	79875	thrombospondin, type I, domain containing 4	metalloendopeptidase activity	Molecular function	-
NLK	51701	nemo-like kinase	transcription, DNA-templated	Biological process	-
MAP2K7	5609	mitogen-activated protein kinase kinase 7	JNK cascade	Biological process	-
PIGK	10026	phosphatidylinositol glycan anchor biosynthesis, class K	protein disulfide isomerase activity	Molecular function	12582175
IL23R	149233	interleukin 23 receptor	positive regulation of interleukin-12 production	Biological process	20027291
CTRC	11330	chymotrypsin C (caldecrin)	peptidase activity	Molecular function	8635596
KCNG2	26251	potassium channel, voltage gated modifier subfamily G, member 2	energy reserve metabolic process	Biological process	-
SLK	9748	STE20-like kinase	cytoplasm	Cellular component	-
VWC2	375567	von Willebrand factor C domain containing 2	extracellular space	Cellular component	17400546
PDPK1	5170	3-phosphoinositide dependent protein kinase 1	calcium-mediated signaling	Biological process	22454520
TXNRD1	7296	thioredoxin reductase 1	cytosol	Cellular component	-
NCF2	4688	neutrophil cytosolic factor 2	response to lipopolysaccharide	Biological process	-
BLM	641	Bloom syndrome, RecQ helicase-like	ATPase activity	Molecular function	17878217
PITX2	5308	paired-like homeodomain 2	embryonic digestive tract morphogenesis	Biological process	-
BCL6	604	B-cell CLL/lymphoma 6	positive regulation of B cell proliferation	Biological process	-
PLA2G5	5322	phospholipase A2, group V	calcium ion binding	Molecular function	-
PDZD8	118987	PDZ domain containing 8	regulation of cell morphogenesis	Biological process	21834987
BUB1	699	BUB1 mitotic checkpoint serine/threonine kinase	nucleoplasm	Cellular component	-
GATA3	2625	GATA binding protein 3	mesenchymal to epithelial transition	Biological process	20189993
NKX2-1	7080	NK2 homeobox 1	positive regulation of circadian rhythm	Biological process	-
RFFL	117584	ring finger and FYVE-like domain containing E3 ubiquitin protein ligase	regulation of fibroblast migration	Biological process	-
ECM1	1893	extracellular matrix protein 1	extracellular exosome	Cellular component	19199708
F12	2161	coagulation factor XII (Hageman factor)	misfolded protein binding	Molecular function	18725990
ZFP36L1	677	ZFP36 ring finger protein-like 1	metal ion binding	Molecular function	-
LARP1	23367	La ribonucleoprotein domain family, member 1	eukaryotic initiation factor 4E binding	Molecular function	20430826
GPER1	2852	G protein-coupled estrogen receptor 1	mineralocorticoid receptor signaling pathway	Biological process	-
FKRP	79147	fukutin related protein	protein O-linked mannosylation	Biological process	25279699
ASAH1	427	N-acylsphingosine amidohydrolase (acid ceramidase) 1	lung development	Biological process	-
SCN4A	6329	sodium channel, voltage gated, type IV alpha subunit	sodium ion transport	Biological process	10218481
MBNL1	4154	muscleblind-like splicing regulator 1	centrosome	Cellular component	-
CLDN24	100132463	claudin 24	structural molecule activity	Molecular function	-
HNMT	3176	histamine N-methyltransferase	histamine N-methyltransferase activity	Molecular function	-
SMAD4	4089	SMAD family member 4	in utero embryonic development	Biological process	-
TGFB3	7043	transforming growth factor, beta 3	mammary gland development	Biological process	-
TSC22D3	1831	TSC22 domain family, member 3	negative regulation of skeletal muscle tissue development	Biological process	-
SNX9	51429	sorting nexin 9	cleavage furrow formation	Biological process	22718350
OR4D6	219983	olfactory receptor, family 4, subfamily D, member 6	plasma membrane	Cellular component	-
GCA	25801	grancalcin, EF-hand calcium binding protein	plasma membrane	Cellular component	-
C2orf49	79074	chromosome 2 open reading frame 49	tRNA-splicing ligase complex	Cellular component	21311021
PGRMC2	10424	progesterone receptor membrane component 2	endomembrane system	Cellular component	-
SLC35B2	347734	solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2	membrane	Cellular component	12716889
PSD3	23362	pleckstrin and Sec7 domain containing 3	ARF guanyl-nucleotide exchange factor activity	Molecular function	-
RHBDD2	57414	rhomboid domain containing 2	Golgi membrane	Cellular component	-
MRPS34	65993	mitochondrial ribosomal protein S34	ribosome	Cellular component	-
ZBTB48	3104	zinc finger and BTB domain containing 48	cytoplasm	Cellular component	-
LAMTOR5	10542	late endosomal/lysosomal adaptor, MAPK and MTOR activator 5	protein localization to lysosome	Biological process	22980980
PSMA2	5683	proteasome (prosome, macropain) subunit, alpha type, 2	antigen processing and presentation of peptide antigen via MHC class I	Biological process	-
FYN	2534	FYN proto-oncogene, Src family tyrosine kinase	nucleus	Cellular component	-
EDEM1	9695	ER degradation enhancer, mannosidase alpha-like 1	cellular protein metabolic process	Biological process	-
APOBEC3H	164668	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H	DNA cytosine deamination	Biological process	16571802
SLC8A1	6546	solute carrier family 8 (sodium/calcium exchanger), member 1	T-tubule	Cellular component	17614935
ITCH	83737	itchy E3 ubiquitin protein ligase	negative regulation of defense response to virus	Biological process	19881509
PYGL	5836	phosphorylase, glycogen, liver	ATP binding	Molecular function	10949035
VEGFA	7422	vascular endothelial growth factor A	positive regulation of endothelial cell migration	Biological process	10022831
MYC	4609	v-myc avian myelocytomatosis viral oncogene homolog	regulation of gene expression	Biological process	21447833
CDH2	1000	cadherin 2, type 1, N-cadherin (neuronal)	protein phosphatase binding	Molecular function	-
HPS4	89781	Hermansky-Pudlak syndrome 4	positive regulation of eye pigmentation	Biological process	11836498
FGFR2	2263	fibroblast growth factor receptor 2	Fc-epsilon receptor signaling pathway	Biological process	-
ARRB1	408	arrestin, beta 1	enzyme inhibitor activity	Molecular function	2163110
FOPNL	123811	FGFR1OP N-terminal like	microtubule anchoring	Biological process	-
TRPM1	4308	transient receptor potential cation channel, subfamily M, member 1	cellular response to light stimulus	Biological process	19896109
SYT5	6861	synaptotagmin V	synaptic vesicle exocytosis	Biological process	-
DPP4	1803	dipeptidyl-peptidase 4	identical protein binding	Molecular function	22001206
HOXD9	3235	homeobox D9	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	1756725
GPR160	26996	G protein-coupled receptor 160	G-protein coupled receptor signaling pathway	Biological process	-
XRCC2	7516	X-ray repair complementing defective repair in Chinese hamster cells 2	centrosome organization	Biological process	21276791
ERCC4	2072	excision repair cross-complementation group 4	double-strand break repair via homologous recombination	Biological process	14728600
LCE1B	353132	late cornified envelope 1B	protein binding	Molecular function	25416956
BRD7	29117	bromodomain containing 7	lysine-acetylated histone binding	Molecular function	16265664
CYP27B1	1594	cytochrome P450, family 27, subfamily B, polypeptide 1	oxidation-reduction process	Biological process	-
ADAMTS9	56999	ADAM metallopeptidase with thrombospondin type 1 motif, 9	positive regulation of melanocyte differentiation	Biological process	-
MRPS10	55173	mitochondrial ribosomal protein S10	positive regulation of defense response to virus by host	Biological process	22020285
HEG1	57493	heart development protein with EGF-like domains 1	post-embryonic development	Biological process	-
DDOST	1650	dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)	endoplasmic reticulum	Cellular component	-
CCDC68	80323	coiled-coil domain containing 68	protein binding	Molecular function	25416956
TUBA1B	10376	tubulin, alpha 1b	microtubule-based process	Biological process	12090300
PIK3C2G	5288	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma	innate immune response	Biological process	-
APOL4	80832	apolipoprotein L, 4	lipid transport	Biological process	-
ADORA2A	135	adenosine A2a receptor	integral component of plasma membrane	Cellular component	21393508
SPTBN4	57731	spectrin, beta, non-erythrocytic 4	ankyrin binding	Molecular function	-
MR1	3140	major histocompatibility complex, class I-related	peptide antigen binding	Molecular function	-
ADSS	159	adenylosuccinate synthase	AMP biosynthetic process	Biological process	15786719
NMU	10874	neuromedin U	digestion	Biological process	7619205
ICMT	23463	isoprenylcysteine carboxyl methyltransferase	regulation of RNA biosynthetic process	Biological process	-
USP46	64854	ubiquitin specific peptidase 46	protein binding	Molecular function	19075014
MPP3	4356	membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)	integral component of plasma membrane	Cellular component	8824795
ACTR2	10097	ARP2 actin-related protein 2 homolog (yeast)	actin cytoskeleton	Cellular component	9230079
TLN1	7094	talin 1	ruffle	Cellular component	-
ZNF347	84671	zinc finger protein 347	transcription, DNA-templated	Biological process	-
GNAT3	346562	guanine nucleotide binding protein, alpha transducing 3	adenylate cyclase-modulating G-protein coupled receptor signaling pathway	Biological process	-
GPR139	124274	G protein-coupled receptor 139	neuropeptide signaling pathway	Biological process	-
ALDH18A1	5832	aldehyde dehydrogenase 18 family, member A1	oxidation-reduction process	Biological process	-
NR0B2	8431	nuclear receptor subfamily 0, group B, member 2	positive regulation of insulin secretion	Biological process	-
CCDC59	29080	coiled-coil domain containing 59	nucleus	Cellular component	-
RPS13	6207	ribosomal protein S13	mRNA binding	Molecular function	17881366
CXXC5	51523	CXXC finger protein 5	sequence-specific DNA binding	Molecular function	23303788
ITGA8	8516	integrin, alpha 8	dendritic spine membrane	Cellular component	-
YARS2	51067	tyrosyl-tRNA synthetase 2, mitochondrial	tRNA binding	Molecular function	15779907
CDKN2D	1032	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	cytoplasm	Cellular component	15750620
NONO	4841	non-POU domain containing, octamer-binding	nuclear speck	Cellular component	-
PNPLA7	375775	patatin-like phospholipase domain containing 7	lipid metabolic process	Biological process	-
DHRS3	9249	dehydrogenase/reductase (SDR family) member 3	phototransduction, visible light	Biological process	-
AGT	183	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	peristalsis	Biological process	-
ZNF850	342892	zinc finger protein 850	metal ion binding	Molecular function	-
CDC42	998	cell division cycle 42	dendritic cell migration	Biological process	-
NBN	4683	nibrin	blastocyst growth	Biological process	-
PAX1	5075	paired box 1	thymus development	Biological process	-
FNTB	2342	farnesyltransferase, CAAX box, beta	wound healing	Biological process	-
SNW1	22938	SNW domain containing 1	cellular response to retinoic acid	Biological process	19934264
PRKDC	5591	protein kinase, DNA-activated, catalytic polypeptide	pro-B cell differentiation	Biological process	-
BIRC5	332	baculoviral IAP repeat containing 5	mitotic nuclear division	Biological process	16291752
FGF17	8822	fibroblast growth factor 17	neurotrophin TRK receptor signaling pathway	Biological process	-
LRFN3	79414	leucine rich repeat and fibronectin type III domain containing 3	axon	Cellular component	-
PYCARD	29108	PYD and CARD domain containing	positive regulation of T cell migration	Biological process	-
FIG4	9896	FIG4 phosphoinositide 5-phosphatase	phosphatidylinositol-3-phosphate biosynthetic process	Biological process	-
OR4X2	119764	olfactory receptor, family 4, subfamily X, member 2 (gene/pseudogene)	plasma membrane	Cellular component	-
COL24A1	255631	collagen, type XXIV, alpha 1	protein binding	Molecular function	25416956
AMZ2	51321	archaelysin family metallopeptidase 2	zinc ion binding	Molecular function	-
TRA2B	6434	transformer 2 beta homolog (Drosophila)	mRNA splicing, via spliceosome	Biological process	9546399
CNOT7	29883	CCR4-NOT transcription complex, subunit 7	membrane	Cellular component	19946888
MAFF	23764	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F	blood coagulation	Biological process	-
SMARCAD1	56916	SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1	chromatin remodeling	Biological process	21549307
CREM	1390	cAMP responsive element modulator	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
SLC25A30	253512	solute carrier family 25, member 30	mitochondrial inner membrane	Cellular component	-
VHLL	391104	von Hippel-Lindau tumor suppressor-like	ubiquitin protein ligase activity	Molecular function	-
CTDP1	9150	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1	spindle	Cellular component	22692537
PRKAR1A	5573	protein kinase, cAMP-dependent, regulatory, type I, alpha	blood coagulation	Biological process	-
ATG7	10533	autophagy related 7	protein lipidation	Biological process	12890687
RC3H2	54542	ring finger and CCCH-type domains 2	lung alveolus development	Biological process	-
TNFRSF10B	8795	tumor necrosis factor receptor superfamily, member 10b	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	Biological process	22934019
APC	324	adenomatous polyposis coli	microtubule plus-end binding	Molecular function	19632184
PPP1R9A	55607	protein phosphatase 1, regulatory subunit 9A	neuron projection development	Biological process	-
STXBP5L	9515	syntaxin binding protein 5-like	integral component of membrane	Cellular component	-
STK3	6788	serine/threonine kinase 3	hepatocyte apoptotic process	Biological process	-
VCAM1	7412	vascular cell adhesion molecule 1	leukocyte cell-cell adhesion	Biological process	1381355
KCND1	3750	potassium channel, voltage gated Shal related subfamily D, member 1	integral component of membrane	Cellular component	-
FXN	2395	frataxin	small molecule metabolic process	Biological process	-
XCR1	2829	chemokine (C motif) receptor 1	chemotaxis	Biological process	-
PAG1	55824	phosphoprotein membrane anchor with glycosphingolipid microdomains 1	negative regulation of T cell activation	Biological process	-
MED1	5469	mediator complex subunit 1	mammary gland branching involved in thelarche	Biological process	-
HOMER1	9456	homer scaffolding protein 1	neuronal postsynaptic density	Cellular component	-
ABCA12	26154	ATP-binding cassette, sub-family A (ABC1), member 12	integral component of plasma membrane	Cellular component	-
BTBD2	55643	BTB (POZ) domain containing 2	protein binding	Molecular function	12878161
IDUA	3425	iduronidase, alpha-L-	limb morphogenesis	Biological process	-
SERPINA6	866	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6	extracellular space	Cellular component	16502470
RARRES1	5918	retinoic acid receptor responder (tazarotene induced) 1	negative regulation of cell proliferation	Biological process	-
CAMK2D	817	calcium/calmodulin-dependent protein kinase II delta	positive regulation of smooth muscle cell proliferation	Biological process	-
NPPA	4878	natriuretic peptide A	positive regulation of potassium ion export across plasma membrane	Biological process	19646991
LIPT2	387787	lipoyl(octanoyl) transferase 2 (putative)	protein lipoylation	Biological process	-
RRAS2	22800	related RAS viral (r-ras) oncogene homolog 2	positive regulation of cell migration	Biological process	-
ACHE	43	acetylcholinesterase (Yt blood group)	beta-amyloid binding	Molecular function	11283752
IL6	3569	interleukin 6	regulation of angiogenesis	Biological process	8557680
TSSK3	81629	testis-specific serine kinase 3	protein binding	Molecular function	25416956
DDIT4L	115265	DNA-damage-inducible transcript 4-like	protein binding	Molecular function	16189514
ARHGAP6	395	Rho GTPase activating protein 6	GTPase activator activity	Molecular function	-
ASCL1	429	achaete-scute family bHLH transcription factor 1	adrenal chromaffin cell differentiation	Biological process	-
DYNC1I2	1781	dynein, cytoplasmic 1, intermediate chain 2	cytoplasmic dynein complex	Cellular component	-
TANK	10010	TRAF family member-associated NFKB activator	ubiquitin protein ligase binding	Molecular function	11279055
WNT9B	7484	wingless-type MMTV integration site family, member 9B	cellular response to starvation	Biological process	-
ATP2B4	493	ATPase, Ca++ transporting, plasma membrane 4	T-tubule	Cellular component	19287093
MTHFD2	10797	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase	extracellular space	Cellular component	22664934
RNF20	56254	ring finger protein 20, E3 ubiquitin protein ligase	ubiquitin-dependent protein catabolic process	Biological process	19037095
BMP8B	656	bone morphogenetic protein 8b	SMAD protein signal transduction	Biological process	-
SLC17A3	10786	solute carrier family 17 (organic anion transporter), member 3	perinuclear region of cytoplasm	Cellular component	15505377
STK11IP	114790	serine/threonine kinase 11 interacting protein	lysosomal membrane	Cellular component	17897319
POU3F3	5455	POU class 3 homeobox 3	metanephric macula densa development	Biological process	-
SERPINF2	5345	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2	negative regulation of fibrinolysis	Biological process	134998
IKBKG	8517	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	toll-like receptor 3 signaling pathway	Biological process	-
IGF2R	3482	insulin-like growth factor 2 receptor	clathrin coat	Cellular component	-
ROCK1	6093	Rho-associated, coiled-coil containing protein kinase 1	lamellipodium	Cellular component	-
EIF2S3	1968	eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa	extracellular exosome	Cellular component	20458337
TMEM101	84336	transmembrane protein 101	integral component of membrane	Cellular component	-
RALGAPA1	253959	Ral GTPase activating protein, alpha subunit 1 (catalytic)	cytoplasm	Cellular component	-
BHLHB9	80823	basic helix-loop-helix domain containing, class B, 9	positive regulation of neurogenesis	Biological process	-
THBS1	7057	thrombospondin 1	positive regulation of blood vessel endothelial cell migration	Biological process	18555217
OR8H1	219469	olfactory receptor, family 8, subfamily H, member 1	G-protein coupled receptor activity	Molecular function	-
PRND	23627	prion protein 2 (dublet)	plasma membrane	Cellular component	-
TAF7	6879	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa	positive transcription elongation factor complex b	Cellular component	18391197
MTNR1A	4543	melatonin receptor 1A	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	Biological process	9645677
ACTB	60	actin, beta	innate immune response	Biological process	-
PI3	5266	peptidase inhibitor 3, skin-derived	copulation	Biological process	-
PINX1	54984	PIN2/TERF1 interacting, telomerase inhibitor 1	negative regulation of cell proliferation	Biological process	11003615
CORO7	79585	coronin 7	protein binding	Molecular function	21130766
NGLY1	55768	N-glycanase 1	cytoplasm	Cellular component	15358861
PDGFRB	5159	platelet-derived growth factor receptor, beta polypeptide	cell migration	Biological process	2554309
TFRC	7037	transferrin receptor	extracellular space	Cellular component	22664934
EPHB3	2049	EPH receptor B3	ephrin receptor activity	Molecular function	15536074
NT5C1A	84618	5'-nucleotidase, cytosolic IA	pyrimidine nucleoside catabolic process	Biological process	-
RANBP2	5903	RAN binding protein 2	Ran GTPase binding	Molecular function	7603572
PAX2	5076	paired box 2	negative regulation of cytolysis	Biological process	19118900
ITGA2	3673	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	positive regulation of alkaline phosphatase activity	Biological process	-
ATOX1	475	antioxidant 1 copper chaperone	response to reactive oxygen species	Biological process	-
JUNB	3726	jun B proto-oncogene	cellular response to hormone stimulus	Biological process	-
CPNE3	8895	copine III	phospholipid metabolic process	Biological process	-
HSPA12B	116835	heat shock 70kD protein 12B	ATP binding	Molecular function	-
ADIPOQ	9370	adiponectin, C1Q and collagen domain containing	negative regulation of synaptic transmission	Biological process	17327472
PAH	5053	phenylalanine hydroxylase	phenylalanine 4-monooxygenase activity	Molecular function	20667834
BBS7	55212	Bardet-Biedl syndrome 7	nucleus	Cellular component	-
ABCA1	19	ATP-binding cassette, sub-family A (ABC1), member 1	high-density lipoprotein particle	Cellular component	-
H2BFS	54145	H2B histone family, member S (pseudogene)	antibacterial humoral response	Biological process	12860195
RUFY1	80230	RUN and FYVE domain containing 1	endocytosis	Biological process	-
CHD6	84181	chromodomain helicase DNA binding protein 6	DNA-directed RNA polymerase II, core complex	Cellular component	17027977
TAF9	6880	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa	pre-snoRNP complex	Cellular component	17636026
SGOL1	151648	shugoshin-like 1 (S. pombe)	protein binding	Molecular function	16541025
NPM1	4869	nucleophosmin (nucleolar phosphoprotein B23, numatrin)	regulation of eIF2 alpha phosphorylation by dsRNA	Biological process	12882984
EED	8726	embryonic ectoderm development	protein binding	Molecular function	16357870
FAM19A2	338811	family with sequence similarity 19 (chemokine (C-C motif)-like), member A2	cytoplasm	Cellular component	-
CHAT	1103	choline O-acetyltransferase	neurotransmitter secretion	Biological process	-
GPLD1	2822	glycosylphosphatidylinositol specific phospholipase D1	intracellular membrane-bounded organelle	Cellular component	1833386
MSH3	4437	mutS homolog 3	mismatched DNA binding	Molecular function	8942985
MAP3K5	4217	mitogen-activated protein kinase kinase kinase 5	activation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	14761963
FOXC1	2296	forkhead box C1	neural crest cell development	Biological process	-
POMK	84197	protein-O-mannose kinase	neuron migration	Biological process	-
SOD3	6649	superoxide dismutase 3, extracellular	extracellular space	Cellular component	20551380
MEI4	101928601	meiosis-specific 4 homolog (S. cerevisiae)	meiotic DNA double-strand break formation	Biological process	-
SRSF3	6428	serine/arginine-rich splicing factor 3	RNA binding	Molecular function	2030943
LAMTOR1	55004	late endosomal/lysosomal adaptor, MAPK and MTOR activator 1	cell growth	Biological process	20381137
STMN3	50861	stathmin-like 3	regulation of microtubule polymerization or depolymerization	Biological process	-
SFSWAP	6433	splicing factor, suppressor of white-apricot family	transcription, DNA-templated	Biological process	-
IL12B	3593	interleukin 12B	positive regulation of tyrosine phosphorylation of Stat3 protein	Biological process	12023369
TRERF1	55809	transcriptional regulating factor 1	homeostatic process	Biological process	11349124
BDNF	627	brain-derived neurotrophic factor	positive regulation of long-term neuronal synaptic plasticity	Biological process	-
BOK	666	BCL2-related ovarian killer	BH domain binding	Molecular function	-
DRD1	1812	dopamine receptor D1	response to amphetamine	Biological process	-
PRMT1	3276	protein arginine methyltransferase 1	cytosol	Cellular component	-
UQCRB	7381	ubiquinol-cytochrome c reductase binding protein	mitochondrial inner membrane	Cellular component	-
EMILIN1	11117	elastin microfibril interfacer 1	extracellular region	Cellular component	-
HILS1	373861	histone linker H1 domain, spermatid-specific 1, pseudogene	transcription, DNA-templated	Biological process	-
SGIP1	84251	SH3-domain GRB2-like (endophilin) interacting protein 1	phospholipid binding	Molecular function	-
WDR46	9277	WD repeat domain 46	poly(A) RNA binding	Molecular function	22658674
XIAP	331	X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase	mitotic spindle assembly	Biological process	-
TWF2	11344	twinfilin actin-binding protein 2	perinuclear region of cytoplasm	Cellular component	12807912
RFC1	5981	replication factor C (activator 1) 1, 145kDa	DNA repair	Biological process	-
NCKAP1L	3071	NCK-associated protein 1-like	maintenance of cell polarity	Biological process	16417406
LIPG	9388	lipase, endothelial	regulation of lipoprotein metabolic process	Biological process	-
CCL3	6348	chemokine (C-C motif) ligand 3	negative regulation of osteoclast differentiation	Biological process	21403648
PRKAG2	51422	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	mitochondrion organization	Biological process	-
UBC	7316	ubiquitin C	gene expression	Biological process	-
EGR2	1959	early growth response 2	cellular response to gonadotropin stimulus	Biological process	-
CHD5	26038	chromodomain helicase DNA binding protein 5	positive regulation of signal transduction by p53 class mediator	Biological process	-
DDAH1	23576	dimethylarginine dimethylaminohydrolase 1	metal ion binding	Molecular function	-
GPHN	10243	gephyrin	glycine receptor clustering	Biological process	-
PSME3	10197	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition	Biological process	-
LAT	27040	linker for activation of T cells	T cell receptor signaling pathway	Biological process	-
ADAM17	6868	ADAM metallopeptidase domain 17	actin cytoskeleton	Cellular component	17010968
LEP	3952	leptin	positive regulation of tyrosine phosphorylation of Stat3 protein	Biological process	-
MYH9	4627	myosin, heavy chain 9, non-muscle	integrin complex	Cellular component	10822899
HCLS1	3059	hematopoietic cell-specific Lyn substrate 1	positive regulation of peptidyl-tyrosine phosphorylation	Biological process	23001182
TAB2	23118	TGF-beta activated kinase 1/MAP3K7 binding protein 2	K63-linked polyubiquitin binding	Molecular function	19935683
AARS2	57505	alanyl-tRNA synthetase 2, mitochondrial	zinc ion binding	Molecular function	-
ZIM2	23619	zinc finger, imprinted 2	sequence-specific DNA binding RNA polymerase II transcription factor activity	Molecular function	-
DNAJC1	64215	DnaJ (Hsp40) homolog, subfamily C, member 1	protein folding	Biological process	-
Mar-08	220972	membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase	MHC class II protein binding	Molecular function	-
KIAA1191	57179	KIAA1191	biological_process	Biological process	-
DDAH2	23564	dimethylarginine dimethylaminohydrolase 2	arginine catabolic process	Biological process	10493931
PDSS2	57107	prenyl (decaprenyl) diphosphate synthase, subunit 2	cytoplasm	Cellular component	-
HOMER1	9456	homer scaffolding protein 1	response to calcium ion	Biological process	14505576
FGFR1OP	11116	FGFR1 oncogene partner	cytosol	Cellular component	-
FOXP3	50943	forkhead box P3	negative regulation of interleukin-5 production	Biological process	-
STAG2	10735	stromal antigen 2	post-translational protein modification	Biological process	-
SAMHD1	25939	SAM domain and HD domain 1	intracellular	Cellular component	11064105
PDLIM7	9260	PDZ and LIM domain 7 (enigma)	protein binding	Molecular function	16189514
PRM3	58531	protamine 3	cell differentiation	Biological process	-
DSG1	1828	desmoglein 1	integral component of membrane	Cellular component	-
MAP2K4	6416	mitogen-activated protein kinase kinase 4	MyD88-independent toll-like receptor signaling pathway	Biological process	-
KIF9	64147	kinesin family member 9	cytoplasm	Cellular component	-
MAP4K1	11184	mitogen-activated protein kinase kinase kinase kinase 1	intracellular	Cellular component	-
TTN	7273	titin	actin filament binding	Molecular function	9501083
CLCN3	1182	chloride channel, voltage-sensitive 3	ion transmembrane transport	Biological process	-
NDN	4692	necdin, melanoma antigen (MAGE) family member	axonal fasciculation	Biological process	-
CXADR	1525	coxsackie virus and adenovirus receptor	regulation of immune response	Biological process	-
VIPR1	7433	vasoactive intestinal peptide receptor 1	receptor complex	Cellular component	23382219
GEMIN8	54960	gem (nuclear organelle) associated protein 8	Gemini of coiled bodies	Cellular component	-
INSRR	3645	insulin receptor-related receptor	peptidyl-tyrosine phosphorylation	Biological process	10226785
FOXN2	3344	forkhead box N2	sequence-specific DNA binding	Molecular function	-
ASF1A	25842	anti-silencing function 1A histone chaperone	DNA repair	Biological process	11897662
ICOSLG	23308	inducible T-cell co-stimulator ligand	B cell activation	Biological process	-
PAX2	5076	paired box 2	axonogenesis	Biological process	9106533
MUC3A	4584	mucin 3A, cell surface associated	cellular protein metabolic process	Biological process	-
APOF	319	apolipoprotein F	lipid transport	Biological process	6816269
NME5	8382	NME/NM23 family member 5	nucleoside diphosphate phosphorylation	Biological process	-
GRIK1	2897	glutamate receptor, ionotropic, kainate 1	central nervous system development	Biological process	10580501
CYP11B2	1585	cytochrome P450, family 11, subfamily B, polypeptide 2	cortisol biosynthetic process	Biological process	9703385
SUN1	23353	Sad1 and UNC84 domain containing 1	lamin binding	Molecular function	-
GRHPR	9380	glyoxylate reductase/hydroxypyruvate reductase	glyoxylate metabolic process	Biological process	-
UHRF2	115426	ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase	nucleus	Cellular component	12176013
MTHFS	10588	5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)	tetrahydrofolate metabolic process	Biological process	19738041
INSR	3643	insulin receptor	positive regulation of respiratory burst	Biological process	9092559
STX17	55014	syntaxin 17	autophagosome membrane	Cellular component	23217709
DCK	1633	deoxycytidine kinase	small molecule metabolic process	Biological process	-
PEX7	5191	peroxisomal biogenesis factor 7	peroxisome	Cellular component	9090382
PRPF4	9128	pre-mRNA processing factor 4	nucleoplasm	Cellular component	-
FDXACB1	91893	ferredoxin-fold anticodon binding domain containing 1	rRNA (uridine-N3-)-methyltransferase activity	Molecular function	-
STMN3	50861	stathmin-like 3	neuron projection development	Biological process	-
KIF16B	55614	kinesin family member 16B	fibroblast growth factor receptor signaling pathway	Biological process	-
FMN2	56776	formin 2	nucleolus	Cellular component	23375502
C4B	721	complement component 4B (Chido blood group)	innate immune response	Biological process	-
WNT5A	7474	wingless-type MMTV integration site family, member 5A	primitive streak formation	Biological process	-
MLEC	9761	malectin	protein folding	Biological process	-
HLA-DPA1	3113	major histocompatibility complex, class II, DP alpha 1	cell surface	Cellular component	20356827
ALDH9A1	223	aldehyde dehydrogenase 9 family, member A1	aldehyde dehydrogenase (NAD) activity	Molecular function	2925663
ALB	213	albumin	maintenance of mitochondrion location	Biological process	16153637
ACER1	125981	alkaline ceramidase 1	sphingolipid metabolic process	Biological process	-
SPTBN4	57731	spectrin, beta, non-erythrocytic 4	axon hillock	Cellular component	-
TUBA3D	113457	tubulin, alpha 3d	cytoplasm	Cellular component	-
AP5M1	55745	adaptor-related protein complex 5, mu 1 subunit	clathrin adaptor complex	Cellular component	-
MAP2K4	6416	mitogen-activated protein kinase kinase 4	toll-like receptor TLR1:TLR2 signaling pathway	Biological process	-
GPATCH4	54865	G patch domain containing 4	poly(A) RNA binding	Molecular function	22658674
HKR1	284459	HKR1, GLI-Kruppel zinc finger family member	regulation of transcription, DNA-templated	Biological process	2850480
GPLD1	2822	glycosylphosphatidylinositol specific phospholipase D1	sodium channel regulator activity	Molecular function	-
COMMD1	150684	copper metabolism (Murr1) domain containing 1	nucleoplasm	Cellular component	-
INPP5K	51763	inositol polyphosphate-5-phosphatase K	lipid phosphatase activity	Molecular function	10753883
ATP6V1B2	526	ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2	insulin receptor signaling pathway	Biological process	-
CCDC114	93233	coiled-coil domain containing 114	cilium	Cellular component	23261303
ZG16	653808	zymogen granule protein 16	carbohydrate binding	Molecular function	-
FGD2	221472	FYVE, RhoGEF and PH domain containing 2	regulation of GTPase activity	Biological process	-
H2AFY	9555	H2A histone family, member Y	nucleosome	Cellular component	9714746
PRKACA	5566	protein kinase, cAMP-dependent, catalytic, alpha	mesoderm formation	Biological process	-
GNG4	2786	guanine nucleotide binding protein (G protein), gamma 4	heterotrimeric G-protein complex	Cellular component	-
CALM2	805	calmodulin 2 (phosphorylase kinase, delta)	small GTPase mediated signal transduction	Biological process	-
TREM2	54209	triggering receptor expressed on myeloid cells 2	axon guidance	Biological process	-
HLA-DRA	3122	major histocompatibility complex, class II, DR alpha	lysosome	Cellular component	8890155
ME2	4200	malic enzyme 2, NAD(+)-dependent, mitochondrial	mitochondrion	Cellular component	-
NCOA3	8202	nuclear receptor coactivator 3	thyroid hormone receptor binding	Molecular function	9346901
HPSE2	60495	heparanase 2 (inactive)	heparan sulfate proteoglycan binding	Molecular function	20576607
NONO	4841	non-POU domain containing, octamer-binding	regulation of circadian rhythm	Biological process	-
SIRT1	23411	sirtuin 1	regulation of gene expression, epigenetic	Biological process	-
BDNF	627	brain-derived neurotrophic factor	synaptic vesicle	Cellular component	-
EDA	1896	ectodysplasin A	positive regulation of canonical Wnt signaling pathway	Biological process	-
BCAT2	587	branched chain amino-acid transaminase 2, mitochondrial	valine metabolic process	Biological process	-
MTMR12	54545	myotubularin related protein 12	phosphatase regulator activity	Molecular function	-
TREM2	54209	triggering receptor expressed on myeloid cells 2	scaffold protein binding	Molecular function	11602640
PLXNB2	23654	plexin B2	regulation of GTPase activity	Biological process	-
NEDD4L	23327	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase	ubiquitin-protein transferase activity	Molecular function	-
VEGFC	7424	vascular endothelial growth factor C	positive regulation of mast cell chemotaxis	Biological process	19275959
DCP1B	196513	decapping mRNA 1B	hydrolase activity	Molecular function	-
CYP27B1	1594	cytochrome P450, family 27, subfamily B, polypeptide 1	calcium ion transport	Biological process	-
PFKFB1	5207	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	response to glucagon	Biological process	-
TUBA3C	7278	tubulin, alpha 3c	GTP binding	Molecular function	-
SDPR	8436	serum deprivation response	membrane raft	Cellular component	25204797
MINK1	50488	misshapen-like kinase 1	actin cytoskeleton reorganization	Biological process	15469942
RPS2	6187	ribosomal protein S2	gene expression	Biological process	-
LTA	4049	lymphotoxin alpha	apoptotic process	Biological process	6334807
MCM4	4173	minichromosome maintenance complex component 4	single-stranded DNA binding	Molecular function	-
CSF1	1435	colony stimulating factor 1 (macrophage)	inflammatory response	Biological process	-
FAM26D	221301	family with sequence similarity 26, member D	cation channel activity	Molecular function	-
KCNA7	3743	potassium channel, voltage gated shaker related subfamily A, member 7	protein homooligomerization	Biological process	-
PTCD2	79810	pentatricopeptide repeat domain 2	liver development	Biological process	-
HMGB1	3146	high mobility group box 1	chromatin remodeling	Biological process	-
RHBDD1	84236	rhomboid domain containing 1	endopeptidase activity	Molecular function	22624035
CRNKL1	51340	crooked neck pre-mRNA splicing factor 1	protein binding	Molecular function	22365833
ABCG1	9619	ATP-binding cassette, sub-family G (WHITE), member 1	amyloid precursor protein catabolic process	Biological process	17293612
BMI1	648	BMI1 proto-oncogene, polycomb ring finger	positive regulation of ubiquitin-protein transferase activity	Biological process	16714294
HIST1H1D	3007	histone cluster 1, H1d	nucleosome assembly	Biological process	-
FAM69A	388650	family with sequence similarity 69, member A	integral component of membrane	Cellular component	-
ERH	2079	enhancer of rudimentary homolog (Drosophila)	osteoblast differentiation	Biological process	-
ASCL1	429	achaete-scute family bHLH transcription factor 1	negative regulation of apoptotic process	Biological process	17507989
ESYT1	23344	extended synaptotagmin-like protein 1	integral component of endoplasmic reticulum membrane	Cellular component	23791178
SOD2	6648	superoxide dismutase 2, mitochondrial	vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure	Biological process	-
LRP1	4035	low density lipoprotein receptor-related protein 1	receptor-mediated endocytosis	Biological process	-
JAK3	3718	Janus kinase 3	protein binding	Molecular function	9045636
NDUFB11	54539	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa	integral component of membrane	Cellular component	-
SLC22A16	85413	solute carrier family 22 (organic cation/carnitine transporter), member 16	acid secretion	Biological process	12089149
CHMP2B	25978	charged multivesicular body protein 2B	endosomal transport	Biological process	-
MCM8	84515	minichromosome maintenance complex component 8	double-strand break repair via homologous recombination	Biological process	-
CYLD	1540	cylindromatosis (turban tumor syndrome)	innate immune response	Biological process	-
NRM	11270	nurim (nuclear envelope membrane protein)	nuclear inner membrane	Cellular component	-
VTN	7448	vitronectin	heparin binding	Molecular function	-
ZNF184	7738	zinc finger protein 184	transcription, DNA-templated	Biological process	-
RAN	5901	RAN, member RAS oncogene family	chromatin	Cellular component	1961752
AP1S2	8905	adaptor-related protein complex 1, sigma 2 subunit	protein transporter activity	Molecular function	-
CXCL12	6387	chemokine (C-X-C motif) ligand 12	receptor binding	Molecular function	10358157
NFAT5	10725	nuclear factor of activated T-cells 5, tonicity-responsive	sequence-specific DNA binding transcription factor activity	Molecular function	10051678
ST20	400410	suppressor of tumorigenicity 20	negative regulation of intrinsic apoptotic signaling pathway	Biological process	-
GRIP1	23426	glutamate receptor interacting protein 1	neuron projection	Cellular component	-
SLC17A3	10786	solute carrier family 17 (organic anion transporter), member 3	plasma membrane	Cellular component	-
BHLHB9	80823	basic helix-loop-helix domain containing, class B, 9	extracellular exosome	Cellular component	19056867
PCCA	5095	propionyl CoA carboxylase, alpha polypeptide	small molecule metabolic process	Biological process	-
MYO5B	4645	myosin VB	microfilament motor activity	Molecular function	-
SULT1A2	6799	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2	catecholamine metabolic process	Biological process	-
GNPAT	8443	glyceronephosphate O-acyltransferase	response to drug	Biological process	-
RHOB	388	ras homolog family member B	early endosome	Cellular component	-
WNT3A	89780	wingless-type MMTV integration site family, member 3A	hippocampus development	Biological process	-
PIAS2	9063	protein inhibitor of activated STAT, 2	negative regulation of androgen receptor signaling pathway	Biological process	11477070
CDKN1C	1028	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	kidney development	Biological process	-
RAB5B	5869	RAB5B, member RAS oncogene family	endosome	Cellular component	10491193
PPP1R2P9	80316	protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9	protein phosphatase inhibitor activity	Molecular function	11076525
SNAP47	116841	synaptosomal-associated protein, 47kDa	exocytosis	Biological process	-
NFKBIA	4792	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	regulation of NF-kappaB import into nucleus	Biological process	3140380
RAB6A	5870	RAB6A, member RAS oncogene family	membrane	Cellular component	12447383
RELN	5649	reelin	positive regulation of small GTPase mediated signal transduction	Biological process	-
GHRHR	2692	growth hormone releasing hormone receptor	peptide hormone binding	Molecular function	7680413
FAN1	22909	FANCD2/FANCI-associated nuclease 1	5'-flap endonuclease activity	Molecular function	20603015
ZNF217	7764	zinc finger protein 217	negative regulation of transcription from RNA polymerase II promoter	Biological process	17130829
SNTB2	6645	syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)	poly(A) RNA binding	Molecular function	22658674
NME7	29922	NME/NM23 family member 7	CTP biosynthetic process	Biological process	-
SLC1A6	6511	solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6	plasma membrane	Cellular component	-
LGALS9C	654346	lectin, galactoside-binding, soluble, 9C	protein binding	Molecular function	25416956
CKLF	51192	chemokine-like factor	extracellular region	Cellular component	11415443
CABP7	164633	calcium binding protein 7	plasma membrane	Cellular component	-
ZNF737	100129842	zinc finger protein 737	DNA binding	Molecular function	-
FRMPD2	143162	FERM and PDZ domain containing 2	bicellular tight junction	Cellular component	19706687
MBNL1	4154	muscleblind-like splicing regulator 1	cytoplasm	Cellular component	-
WT1	7490	Wilms tumor 1	metanephric mesenchyme development	Biological process	-
SLC37A1	54020	solute carrier family 37 (glucose-6-phosphate transporter), member 1	integral component of membrane	Cellular component	-
RUFY1	80230	RUN and FYVE domain containing 1	protein transport	Biological process	-
HIST1H3J	8356	histone cluster 1, H3j	extracellular exosome	Cellular component	20458337
CD1D	912	CD1d molecule	innate immune response	Biological process	-
TNKS	8658	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase	mitotic nuclear division	Biological process	-
CSNK2A1	1457	casein kinase 2, alpha 1 polypeptide	transcription, DNA-templated	Biological process	-
NUP93	9688	nucleoporin 93kDa	gene expression	Biological process	-
RPS6KA2	6196	ribosomal protein S6 kinase, 90kDa, polypeptide 2	negative regulation of meiotic nuclear division	Biological process	-
ANKS1A	23294	ankyrin repeat and sterile alpha motif domain containing 1A	ephrin receptor signaling pathway	Biological process	-
LIPE	3991	lipase, hormone-sensitive	triglyceride lipase activity	Molecular function	-
CLUAP1	23059	clusterin associated protein 1	organelle organization	Biological process	-
BBS4	585	Bardet-Biedl syndrome 4	nonmotile primary cilium	Cellular component	17574030
PAX6	5080	paired box 6	dorsal/ventral axis specification	Biological process	-
SS18	6760	synovial sarcoma translocation, chromosome 18	ligand-dependent nuclear receptor transcription coactivator activity	Molecular function	15919756
HSF1	3297	heat shock transcription factor 1	mRNA transcription	Biological process	21597468
TARDBP	23435	TAR DNA binding protein	negative regulation of gene expression	Biological process	18305152
CYSLTR1	10800	cysteinyl leukotriene receptor 1	inflammatory response	Biological process	-
MCRS1	10445	microspherule protein 1	histone H4-K5 acetylation	Biological process	20018852
COX14	84987	COX14 cytochrome c oxidase assembly factor	integral component of membrane	Cellular component	-
PRKRIP1	79706	PRKR interacting protein 1 (IL11 inducible)	nucleolus	Cellular component	-
VPS26B	112936	vacuolar protein sorting 26 homolog B (S. pombe)	early endosome	Cellular component	-
PTPRZ1	5803	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	regulation of oligodendrocyte progenitor proliferation	Biological process	-
SLIT2	9353	slit homolog 2 (Drosophila)	apoptotic process involved in luteolysis	Biological process	18566128
STRC	161497	stereocilin	kinocilium	Cellular component	-
LDB1	8861	LIM domain binding 1	positive regulation of cell adhesion	Biological process	-
HEY2	23493	hes-related family bHLH transcription factor with YRPW motif 2	anterior/posterior axis specification	Biological process	-
LSR	51599	lipolysis stimulated lipoprotein receptor	regulation of lipid metabolic process	Biological process	-
OR51F2	119694	olfactory receptor, family 51, subfamily F, member 2	G-protein coupled receptor signaling pathway	Biological process	-
PRIM1	5557	primase, DNA, polypeptide 1 (49kDa)	DNA replication, synthesis of RNA primer	Biological process	-
RPL10L	140801	ribosomal protein L10-like	cytosolic large ribosomal subunit	Cellular component	12490704
SUPT16H	11198	suppressor of Ty 16 homolog (S. cerevisiae)	DNA repair	Biological process	-
SLC6A14	11254	solute carrier family 6 (amino acid transporter), member 14	integral component of membrane	Cellular component	-
RPS6KA5	9252	ribosomal protein S6 kinase, 90kDa, polypeptide 5	nucleoplasm	Cellular component	-
SPOCK1	6695	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1	nervous system development	Biological process	9181134
RAPGEF3	10411	Rap guanine nucleotide exchange factor (GEF) 3	negative regulation of syncytium formation by plasma membrane fusion	Biological process	23867755
HP	3240	haptoglobin	defense response	Biological process	7036344
SP4	6671	Sp4 transcription factor	regulation of transcription from RNA polymerase II promoter	Biological process	12560508
JUN	3725	jun proto-oncogene	negative regulation of transcription, DNA-templated	Biological process	2833704
WDFY3	23001	WD repeat and FYVE domain containing 3	aggrephagy	Biological process	20417604
ST6GALNAC5	81849	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5	oligosaccharide biosynthetic process	Biological process	12668675
NRCAM	4897	neuronal cell adhesion molecule	axon initial segment	Cellular component	-
WASF2	10163	WAS protein family, member 2	actin binding	Molecular function	-
SATB1	6304	SATB homeobox 1	protein binding	Molecular function	18408014
WNT2	7472	wingless-type MMTV integration site family member 2	Wnt signaling pathway	Biological process	10557084
DBH	1621	dopamine beta-hydroxylase (dopamine beta-monooxygenase)	transport vesicle membrane	Cellular component	-
RCC1	1104	regulator of chromosome condensation 1	viral process	Biological process	-
RNF126	55658	ring finger protein 126	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	Biological process	23418353
HNRNPF	3185	heterogeneous nuclear ribonucleoprotein F	nucleotide binding	Molecular function	-
ZNF721	170960	zinc finger protein 721	metal ion binding	Molecular function	-
PIK3C2B	5287	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta	cytoplasm	Cellular component	-
C6orf89	221477	chromosome 6 open reading frame 89	wound healing	Biological process	21857995
LRP12	29967	low density lipoprotein receptor-related protein 12	signal transduction	Biological process	12809483
ANGPTL3	27329	angiopoietin-like 3	positive regulation of lipid catabolic process	Biological process	12565906
CTDSPL	10217	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like	negative regulation of G1/S transition of mitotic cell cycle	Biological process	-
ZNF486	90649	zinc finger protein 486	extracellular exosome	Cellular component	19056867
C7	730	complement component 7	innate immune response	Biological process	-
TACR1	6869	tachykinin receptor 1	response to morphine	Biological process	-
AGO2	27161	argonaute RISC catalytic component 2	cytosol	Cellular component	-
CFB	629	complement factor B	regulation of complement activation	Biological process	-
CDKAL1	54901	CDK5 regulatory subunit associated protein 1-like 1	4 iron, 4 sulfur cluster binding	Molecular function	-
DPP4	1803	dipeptidyl-peptidase 4	focal adhesion	Cellular component	21423176
MOXD1	26002	monooxygenase, DBH-like 1	protein binding	Molecular function	25416956
SNAPC2	6618	small nuclear RNA activating complex, polypeptide 2, 45kDa	snRNA transcription	Biological process	8524284
ABHD5	51099	abhydrolase domain containing 5	nucleus	Cellular component	-
ZNF148	7707	zinc finger protein 148	Golgi apparatus	Cellular component	-
FLT3LG	2323	fms-related tyrosine kinase 3 ligand	lymphocyte differentiation	Biological process	-
CLDN19	149461	claudin 19	basolateral plasma membrane	Cellular component	16427635
TP53BP1	7158	tumor protein p53 binding protein 1	telomeric DNA binding	Molecular function	-
ACY1	95	aminoacylase 1	xenobiotic metabolic process	Biological process	-
ID3	3399	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	nucleus	Cellular component	14627819
DEPDC7	91614	DEP domain containing 7	biological_process	Biological process	-
CDK18	5129	cyclin-dependent kinase 18	ATP binding	Molecular function	-
HYI	81888	hydroxypyruvate isomerase (putative)	hydroxypyruvate isomerase activity	Molecular function	-
DYNC2LI1	51626	dynein, cytoplasmic 2, light intermediate chain 1	motile primary cilium	Cellular component	-
HIST1H4H	8365	histone cluster 1, H4h	gene expression	Biological process	-
TESK2	10420	testis-specific kinase 2	focal adhesion assembly	Biological process	-
HDAC3	8841	histone deacetylase 3	protein deacetylation	Biological process	17172643
PKP1	5317	plakophilin 1	cell adhesion	Biological process	10852826
TOB2	10766	transducer of ERBB2, 2	nucleus	Cellular component	10602502
RLTPR	146206	RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing	T cell receptor signaling pathway	Biological process	-
GAB1	2549	GRB2-associated binding protein 1	platelet-derived growth factor receptor signaling pathway	Biological process	-
TGM3	7053	transglutaminase 3	cytoplasm	Cellular component	12850301
HLA-A	3105	major histocompatibility complex, class I, A	MHC class I protein complex	Cellular component	-
ALDH1A3	220	aldehyde dehydrogenase 1 family, member A3	locomotory behavior	Biological process	-
HMGN1	3150	high mobility group nucleosome binding domain 1	transcription-coupled nucleotide-excision repair	Biological process	-
EZR	7430	ezrin	cytoplasm	Cellular component	23106337
KIF6	221458	kinesin family member 6	protein binding	Molecular function	16189514
CRHR1	1394	corticotropin releasing hormone receptor 1	immune response	Biological process	7692441
RERG	85004	RAS-like, estrogen-regulated, growth inhibitor	negative regulation of cell growth	Biological process	11533059
ESRRG	2104	estrogen-related receptor gamma	RNA polymerase II regulatory region sequence-specific DNA binding	Molecular function	-
SOD2	6648	superoxide dismutase 2, mitochondrial	respiratory electron transport chain	Biological process	-
DMKN	93099	dermokine	extracellular exosome	Cellular component	23376485
CDK16	5127	cyclin-dependent kinase 16	protein serine/threonine kinase activity	Molecular function	22184064
F8A1	8263	coagulation factor VIII-associated 1	biological_process	Biological process	-
NR2F6	2063	nuclear receptor subfamily 2, group F, member 6	transcription initiation from RNA polymerase II promoter	Biological process	-
SDCBP	6386	syndecan binding protein (syntenin)	neurexin family protein binding	Molecular function	-
HES5	388585	hes family bHLH transcription factor 5	transcription factor binding	Molecular function	17611704
ADGRB2	576	adhesion G protein-coupled receptor B2	G-protein coupled receptor signaling pathway	Biological process	-
GLI2	2736	GLI family zinc finger 2	chromatin binding	Molecular function	-
NFYA	4800	nuclear transcription factor Y, alpha	sequence-specific DNA binding transcription factor activity	Molecular function	-
IL36A	27179	interleukin 36, alpha	inflammatory response	Biological process	-
KIF7	374654	kinesin family member 7	metabolic process	Biological process	-
NEDD4	4734	neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase	endocardial cushion development	Biological process	-
RAD17	5884	RAD17 homolog (S. pombe)	DNA clamp loader activity	Molecular function	-
HCAR3	8843	hydroxycarboxylic acid receptor 3	integral component of plasma membrane	Cellular component	7505609
CDC42EP4	23580	CDC42 effector protein (Rho GTPase binding) 4	poly(A) RNA binding	Molecular function	22658674
SPG20	23111	spastic paraplegia 20 (Troyer syndrome)	mitochondrial outer membrane	Cellular component	21559443
VAV3	10451	vav 3 guanine nucleotide exchange factor	platelet activation	Biological process	-
TSC2	7249	tuberous sclerosis 2	negative regulation of Wnt signaling pathway	Biological process	-
MYH15	22989	myosin, heavy chain 15	myosin filament	Cellular component	-
HIST1H2BC	8347	histone cluster 1, H2bc	protein binding	Molecular function	25416956
NMU	10874	neuromedin U	terminal bouton	Cellular component	-
MRPL43	84545	mitochondrial ribosomal protein L43	mitochondrial translational initiation	Biological process	-
SNCA	6622	synuclein, alpha (non A4 component of amyloid precursor)	Golgi apparatus	Cellular component	-
CMA1	1215	chymase 1, mast cell	extracellular matrix disassembly	Biological process	-
TRAM1	23471	translocation associated membrane protein 1	cotranslational protein targeting to membrane	Biological process	1315422
STK11	6794	serine/threonine kinase 11	membrane	Cellular component	-
RNF8	9025	ring finger protein 8, E3 ubiquitin protein ligase	ubiquitin-dependent protein catabolic process	Biological process	22266820
SPHK1	8877	sphingosine kinase 1	sphingosine-1-phosphate receptor activity	Molecular function	23106337
GRHL2	79977	grainyhead-like 2 (Drosophila)	membrane	Cellular component	-
ACTB	60	actin, beta	cytoplasmic ribonucleoprotein granule	Cellular component	15121898
PMF1	11243	polyamine-modulated factor 1	MIS12/MIND type complex	Cellular component	16585270
GRSF1	2926	G-rich RNA sequence binding factor 1	poly(A) RNA binding	Molecular function	22658674
RYK	6259	receptor-like tyrosine kinase	transmembrane receptor protein tyrosine kinase activity	Molecular function	8386829
RPS21	6227	ribosomal protein S21	viral transcription	Biological process	-
HIBADH	11112	3-hydroxyisobutyrate dehydrogenase	valine catabolic process	Biological process	-
TMED2	10959	transmembrane emp24 domain trafficking protein 2	zymogen granule membrane	Cellular component	-
TRAF6	7189	TNF receptor-associated factor 6, E3 ubiquitin protein ligase	T cell receptor signaling pathway	Biological process	-
RAB11A	8766	RAB11A, member RAS oncogene family	cytoplasmic vesicle	Cellular component	22613965
GSN	2934	gelsolin	positive regulation of protein processing in phagocytic vesicle	Biological process	-
ARR3	407	arrestin 3, retinal (X-arrestin)	visual perception	Biological process	-
ABCF2	10061	ATP-binding cassette, sub-family F (GCN20), member 2	ATP binding	Molecular function	-
TRPC3	7222	transient receptor potential cation channel, subfamily C, member 3	calcium ion transport	Biological process	9215637
TNFRSF1B	7133	tumor necrosis factor receptor superfamily, member 1B	nucleus	Cellular component	-
DGCR14	8220	DiGeorge syndrome critical region gene 14	catalytic step 2 spliceosome	Cellular component	11991638
IFIT2	3433	interferon-induced protein with tetratricopeptide repeats 2	positive regulation of apoptotic process	Biological process	21190939
TFPI	7035	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)	endoplasmic reticulum	Cellular component	-
CCDC85B	11007	coiled-coil domain containing 85B	cytoplasm	Cellular component	-
ITGB3	3690	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	integrin complex	Cellular component	15215180
TMED10	10972	transmembrane emp24-like trafficking protein 10 (yeast)	endoplasmic reticulum membrane	Cellular component	-
FYN	2534	FYN proto-oncogene, Src family tyrosine kinase	cell migration	Biological process	-
ADORA2A	135	adenosine A2a receptor	inflammatory response	Biological process	8360491
HDLBP	3069	high density lipoprotein binding protein	protein binding	Molecular function	24725430
RPL13	6137	ribosomal protein L13	translation	Biological process	-
CDC42EP5	148170	CDC42 effector protein (Rho GTPase binding) 5	JNK cascade	Biological process	-
OPRM1	4988	opioid receptor, mu 1	neuron projection	Cellular component	-
PDGFRB	5159	platelet-derived growth factor receptor, beta polypeptide	metanephric S-shaped body morphogenesis	Biological process	-
CACNG4	27092	calcium channel, voltage-dependent, gamma subunit 4	transport	Biological process	10613843
IRF2BPL	64207	interferon regulatory factor 2 binding protein-like	extracellular space	Cellular component	22664934
DGKI	9162	diacylglycerol kinase, iota	ATP binding	Molecular function	-
KLHL4	56062	kelch-like family member 4	biological_process	Biological process	-
ABCA7	10347	ATP-binding cassette, sub-family A (ABC1), member 7	cholesterol efflux	Biological process	14570867
TSC1	7248	tuberous sclerosis 1	regulation of phosphoprotein phosphatase activity	Biological process	17308101
SLC26A10	65012	solute carrier family 26, member 10	sulfate transmembrane transport	Biological process	-
CCR1	1230	chemokine (C-C motif) receptor 1	dendritic cell chemotaxis	Biological process	16621978
ZNF93	81931	zinc finger protein 93	transcription, DNA-templated	Biological process	-
SNRPE	6635	small nuclear ribonucleoprotein polypeptide E	extracellular exosome	Cellular component	23376485
PPP1R3D	5509	protein phosphatase 1, regulatory subunit 3D	dephosphorylation	Biological process	-
CYP7A1	1581	cytochrome P450, family 7, subfamily A, polypeptide 1	cellular response to glucose stimulus	Biological process	19965590
ATP2B2	491	ATPase, Ca++ transporting, plasma membrane 2	cytosol	Cellular component	17234811
XIAP	331	X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase	ubiquitin protein ligase activity	Molecular function	-
ADCYAP1R1	117	adenylate cyclase activating polypeptide 1 (pituitary) receptor type I	activation of adenylate cyclase activity	Biological process	-
HDC	3067	histidine decarboxylase	histidine catabolic process	Biological process	-
PPIP5K1	9677	diphosphoinositol pentakisphosphate kinase 1	inositol hexakisphosphate 5-kinase activity	Molecular function	17412958
PARD6A	50855	par-6 family cell polarity regulator alpha	cell-cell junction organization	Biological process	-
DPP3	10072	dipeptidyl-peptidase 3	proteolysis	Biological process	10387075
GLRA2	2742	glycine receptor, alpha 2	glycine binding	Molecular function	2155780
RPA1	6117	replication protein A1, 70kDa	in utero embryonic development	Biological process	-
CXCL10	3627	chemokine (C-X-C motif) ligand 10	positive regulation of release of sequestered calcium ion into cytosol	Biological process	12782716
GSS	2937	glutathione synthetase	small molecule metabolic process	Biological process	-
CD14	929	CD14 molecule	response to ethanol	Biological process	-
LDLRAP1	26119	low density lipoprotein receptor adaptor protein 1	cholesterol metabolic process	Biological process	12451172
ESRRA	2101	estrogen-related receptor alpha	zinc ion binding	Molecular function	-
MAPK14	1432	mitogen-activated protein kinase 14	innate immune response	Biological process	-
PDIA3	2923	protein disulfide isomerase family A, member 3	protein N-linked glycosylation via asparagine	Biological process	-
IL1B	3553	interleukin 1, beta	apoptotic process	Biological process	9218611
PDGFA	5154	platelet-derived growth factor alpha polypeptide	microvillus	Cellular component	-
CENPE	1062	centromere protein E, 312kDa	kinesin complex	Cellular component	-
PRDM14	63978	PR domain containing 14	protein binding	Molecular function	21516116
CACNG8	59283	calcium channel, voltage-dependent, gamma subunit 8	postsynaptic density	Cellular component	-
IFT52	51098	intraflagellar transport 52	intraciliary transport particle B	Cellular component	-
WDTC1	23038	WD and tetratricopeptide repeats 1	in utero embryonic development	Biological process	-
BVES	11149	blood vessel epicardial substance	vesicle-mediated transport	Biological process	-
UFL1	23376	UFM1-specific ligase 1	negative regulation of NF-kappaB transcription factor activity	Biological process	20164180
MYZAP	100820829	myocardial zonula adherens protein	protein binding	Molecular function	20412299
SYT4	6860	synaptotagmin IV	calcium-dependent phospholipid binding	Molecular function	-
REEP3	221035	receptor accessory protein 3	integral component of membrane	Cellular component	-
PDE4D	5144	phosphodiesterase 4D, cAMP-specific	voltage-gated calcium channel complex	Cellular component	-
TMSB4Y	9087	thymosin beta 4, Y-linked	sequestering of actin monomers	Biological process	-
BCKDK	10295	branched chain ketoacid dehydrogenase kinase	mitochondrial alpha-ketoglutarate dehydrogenase complex	Cellular component	11839747
EIF5B	9669	eukaryotic translation initiation factor 5B	translation	Biological process	-
E2F5	1875	E2F transcription factor 5, p130-binding	cytoplasm	Cellular component	-
OR4C45	403257	olfactory receptor, family 4, subfamily C, member 45	olfactory receptor activity	Molecular function	-
LHX3	8022	LIM homeobox 3	nucleus	Cellular component	-
SPNS3	201305	spinster homolog 3 (Drosophila)	lysosomal membrane	Cellular component	-
PFKFB2	5208	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2	lactate metabolic process	Biological process	-
EIF2B2	8892	eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa	cytoplasm	Cellular component	11323413
PLK2	10769	polo-like kinase 2	centriole	Cellular component	19001868
POLR2K	5440	polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa	DNA-directed RNA polymerase III complex	Cellular component	-
LRP5	4041	low density lipoprotein receptor-related protein 5	endocytosis	Biological process	-
PREX1	57580	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	perinuclear region of cytoplasm	Cellular component	-
ABCC2	1244	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	plasma membrane	Cellular component	-
CD300A	11314	CD300a molecule	plasma membrane	Cellular component	-
NMI	9111	N-myc (and STAT) interactor	transcription from RNA polymerase II promoter	Biological process	9989503
DHRS4	10901	dehydrogenase/reductase (SDR family) member 4	carbonyl reductase (NADPH) activity	Molecular function	18571493
PI4K2B	55300	phosphatidylinositol 4-kinase type 2 beta	phospholipid metabolic process	Biological process	-
TTC25	83538	tetratricopeptide repeat domain 25	protein binding	Molecular function	25416956
SOHLH2	54937	spermatogenesis and oogenesis specific basic helix-loop-helix 2	transcription, DNA-templated	Biological process	-
TBL2	26608	transducin (beta)-like 2	cellular response to glucose starvation	Biological process	25393282
NRP1	8829	neuropilin 1	integral component of membrane	Cellular component	-
NELFA	7469	negative elongation factor complex member A	protein binding	Molecular function	12612062
KCNJ13	3769	potassium channel, inwardly rectifying subfamily J, member 13	integral component of plasma membrane	Cellular component	-
MRPL48	51642	mitochondrial ribosomal protein L48	mitochondrial ribosome	Cellular component	20601428
FGF10	2255	fibroblast growth factor 10	otic vesicle formation	Biological process	-
MYOC	4653	myocilin, trabecular meshwork inducible glucocorticoid response	extracellular matrix	Cellular component	11773026
ID3	3399	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	notochord development	Biological process	-
PLEKHF1	79156	pleckstrin homology domain containing, family F (with FYVE domain) member 1	phosphatidylinositol-4-phosphate binding	Molecular function	22115783
IFIH1	64135	interferon induced with helicase C domain 1	cytoplasmic pattern recognition receptor signaling pathway in response to virus	Biological process	21616437
ACSL4	2182	acyl-CoA synthetase long-chain family member 4	membrane	Cellular component	19946888
TANK	10010	TRAF family member-associated NFKB activator	cytosol	Cellular component	-
AHRR	57491	aryl-hydrocarbon receptor repressor	DNA binding	Molecular function	-
BMP2	650	bone morphogenetic protein 2	protein destabilization	Biological process	-
SLC5A1	6523	solute carrier family 5 (sodium/glucose cotransporter), member 1	extracellular exosome	Cellular component	19056867
MADCAM1	8174	mucosal vascular addressin cell adhesion molecule 1	membrane	Cellular component	8502297
CYFIP2	26999	cytoplasmic FMR1 interacting protein 2	Fc-gamma receptor signaling pathway involved in phagocytosis	Biological process	-
KANK2	25959	KN motif and ankyrin repeat domains 2	negative regulation of programmed cell death	Biological process	22371500
TSC22D4	81628	TSC22 domain family, member 4	negative regulation of transcription, DNA-templated	Biological process	10488076
CCNA2	890	cyclin A2	viral process	Biological process	-
NRAS	4893	neuroblastoma RAS viral (v-ras) oncogene homolog	actin cytoskeleton organization	Biological process	-
AKR7L	246181	aldo-keto reductase family 7-like (gene/pseudogene)	small molecule metabolic process	Biological process	-
UBE2A	7319	ubiquitin-conjugating enzyme E2A	ubiquitin conjugating enzyme activity	Molecular function	20061386
ARSD	414	arylsulfatase D	extracellular exosome	Cellular component	23376485
CRYL1	51084	crystallin, lambda 1	NAD+ binding	Molecular function	15809331
AGRP	181	agouti related neuropeptide	photoperiodism	Biological process	-
BOLA3	388962	bolA family member 3	cellular_component	Cellular component	-
ZNF212	7988	zinc finger protein 212	protein binding	Molecular function	18255255
RAPGEF2	9693	Rap guanine nucleotide exchange factor (GEF) 2	positive regulation of protein binding	Biological process	-
BTRC	8945	beta-transducin repeat containing E3 ubiquitin protein ligase	cellular response to organic cyclic compound	Biological process	-
SERPINB12	89777	serpin peptidase inhibitor, clade B (ovalbumin), member 12	cytoplasm	Cellular component	11604408
TOP2A	7153	topoisomerase (DNA) II alpha 170kDa	positive regulation of apoptotic process	Biological process	16611985
ENTPD8	377841	ectonucleoside triphosphate diphosphohydrolase 8	plasma membrane	Cellular component	-
UNC13A	23025	unc-13 homolog A (C. elegans)	cell junction	Cellular component	-
CLIC4	25932	chloride intracellular channel 4	regulation of cytoskeleton organization	Biological process	14569596
SRC	6714	SRC proto-oncogene, non-receptor tyrosine kinase	regulation of podosome assembly	Biological process	-
CELSR2	1952	cadherin, EGF LAG seven-pass G-type receptor 2	regulation of cell-cell adhesion	Biological process	-
RNF7	9616	ring finger protein 7	copper ion binding	Molecular function	10082581
ACOT2	10965	acyl-CoA thioesterase 2	palmitoyl-CoA hydrolase activity	Molecular function	-
PTGS2	5743	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	NAD metabolic process	Biological process	-
PRDM4	11108	PR domain containing 4	methylation	Biological process	-
RNF111	54778	ring finger protein 111	transcription initiation from RNA polymerase II promoter	Biological process	-
B3GNT4	79369	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity	Molecular function	11042166
SCRT2	85508	scratch family zinc finger 2	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	Biological process	-
RARB	5915	retinoic acid receptor, beta	multicellular organism growth	Biological process	-
PLK2	10769	polo-like kinase 2	signal transducer activity	Molecular function	12761501
OLFM1	10439	olfactomedin 1	synapse	Cellular component	-
GNAQ	2776	guanine nucleotide binding protein (G protein), q polypeptide	adenylate cyclase-activating G-protein coupled receptor signaling pathway	Biological process	-
DHRS2	10202	dehydrogenase/reductase (SDR family) member 2	negative regulation of apoptotic process	Biological process	19443906
HLA-DRB3	3125	major histocompatibility complex, class II, DR beta 3	endocytic vesicle membrane	Cellular component	-
IFNA1	3439	interferon, alpha 1	humoral immune response	Biological process	-
LDB1	8861	LIM domain binding 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
JUN	3725	jun proto-oncogene	GTPase activator activity	Molecular function	11804590
PKM	5315	pyruvate kinase, muscle	plasma membrane	Cellular component	-
GTF2H2	2966	general transcription factor IIH, polypeptide 2, 44kDa	nucleotide-excision repair, DNA damage removal	Biological process	-
CETN3	1070	centrin, EF-hand protein, 3	nucleolus	Cellular component	-
PATL1	219988	protein associated with topoisomerase II homolog 1 (yeast)	CCR4-NOT complex	Cellular component	20584987
KLF15	28999	Kruppel-like factor 15	cellular response to peptide	Biological process	-
OSBPL6	114880	oxysterol binding protein-like 6	protein binding	Molecular function	22190034
RPL24	6152	ribosomal protein L24	optic nerve development	Biological process	-
RREB1	6239	ras responsive element binding protein 1	negative regulation of transcription from RNA polymerase II promoter	Biological process	20133935
TRIAP1	51499	TP53 regulated inhibitor of apoptosis 1	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	Biological process	15735003
RELA	5970	v-rel avian reticuloendotheliosis viral oncogene homolog A	I-kappaB/NF-kappaB complex	Cellular component	-
CPSF3	51692	cleavage and polyadenylation specific factor 3, 73kDa	termination of RNA polymerase II transcription	Biological process	-
RAP2B	5912	RAP2B, member of RAS oncogene family	negative regulation of cell migration	Biological process	-
CXADR	1525	coxsackie virus and adenovirus receptor	basolateral plasma membrane	Cellular component	11316797
FGF14	2259	fibroblast growth factor 14	adult locomotory behavior	Biological process	-
FEV	54738	FEV (ETS oncogene family)	neuron maturation	Biological process	-
TERF1	7013	telomeric repeat binding factor (NIMA-interacting) 1	mitotic spindle assembly checkpoint	Biological process	11943150
RPL34	6164	ribosomal protein L34	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Biological process	-
INCENP	3619	inner centromere protein antigens 135/155kDa	cytosol	Cellular component	-
CD209	30835	CD209 molecule	cytoplasm	Cellular component	11337487
CDK14	5218	cyclin-dependent kinase 14	ATP binding	Molecular function	-
UGT1A9	54600	UDP glucuronosyltransferase 1 family, polypeptide A9	cellular glucuronidation	Biological process	20610558
ABAT	18	4-aminobutyrate aminotransferase	response to hypoxia	Biological process	-
RAG1	5896	recombination activating gene 1	protein binding	Molecular function	17474147
YAP1	10413	Yes-associated protein 1	somatic stem cell maintenance	Biological process	-
AGBL5	60509	ATP/GTP binding protein-like 5	protein deglutamylation	Biological process	-
PTCHD4	442213	patched domain containing 4	molecular_function	Molecular function	-
NFIB	4781	nuclear factor I/B	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	19540848
GNAT3	346562	guanine nucleotide binding protein, alpha transducing 3	GTP binding	Molecular function	-
HMGCR	3156	3-hydroxy-3-methylglutaryl-CoA reductase	response to nutrient	Biological process	-
CPSF3	51692	cleavage and polyadenylation specific factor 3, 73kDa	ribonucleoprotein complex	Cellular component	-
PABPC4	8761	poly(A) binding protein, cytoplasmic 4 (inducible form)	nucleotide binding	Molecular function	-
ASXL3	80816	additional sex combs like transcriptional regulator 3	DNA binding	Molecular function	-
CRY1	1407	cryptochrome circadian clock 1	core promoter binding	Molecular function	-
PDCD10	11235	programmed cell death 10	angiogenesis	Biological process	-
SCIN	85477	scinderin	sequestering of actin monomers	Biological process	19666531
FGF1	2246	fibroblast growth factor 1 (acidic)	regulation of endothelial cell chemotaxis to fibroblast growth factor	Biological process	16756958
FABP5	2171	fatty acid binding protein 5 (psoriasis-associated)	epidermis development	Biological process	1512466
GABRA4	2557	gamma-aminobutyric acid (GABA) A receptor, alpha 4	integral component of plasma membrane	Cellular component	8719416
NUFIP1	26747	nuclear fragile X mental retardation protein interacting protein 1	metal ion binding	Molecular function	-
SYVN1	84447	synovial apoptosis inhibitor 1, synoviolin	smooth endoplasmic reticulum	Cellular component	16186510
FDFT1	2222	farnesyl-diphosphate farnesyltransferase 1	farnesyl diphosphate metabolic process	Biological process	-
RGS7BP	401190	regulator of G-protein signaling 7 binding protein	G-protein coupled receptor signaling pathway	Biological process	-
YWHAH	7533	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta	regulation of neuron differentiation	Biological process	-
DYRK4	8798	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4	ATP binding	Molecular function	-
FOSL2	2355	FOS-like antigen 2	response to morphine	Biological process	-
PORCN	64840	porcupine homolog (Drosophila)	protein palmitoleylation	Biological process	-
CBS	875	cystathionine-beta-synthase	protein binding	Molecular function	17087506
MNDA	4332	myeloid cell nuclear differentiation antigen	positive regulation of apoptotic process	Biological process	17875758
ETS1	2113	v-ets avian erythroblastosis virus E26 oncogene homolog 1	cellular response to hydrogen peroxide	Biological process	-
HLA-B	3106	major histocompatibility complex, class I, B	phagocytic vesicle membrane	Cellular component	-
CD14	929	CD14 molecule	toll-like receptor 2 signaling pathway	Biological process	-
PTPN1	5770	protein tyrosine phosphatase, non-receptor type 1	positive regulation of protein tyrosine kinase activity	Biological process	21216966
PIP5K1A	8394	phosphatidylinositol-4-phosphate 5-kinase, type I, alpha	ruffle assembly	Biological process	20660631
PRKACA	5566	protein kinase, cAMP-dependent, catalytic, alpha	fibroblast growth factor receptor signaling pathway	Biological process	-
CDC7	8317	cell division cycle 7	double-strand break repair via break-induced replication	Biological process	-
OSM	5008	oncostatin M	negative regulation of hormone secretion	Biological process	7867561
NR3C1	2908	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	signal transduction	Biological process	7769088
SLC30A1	7779	solute carrier family 30 (zinc transporter), member 1	negative regulation of neurotransmitter secretion	Biological process	-
RPL13	6137	ribosomal protein L13	SRP-dependent cotranslational protein targeting to membrane	Biological process	-
UBE2C	11065	ubiquitin-conjugating enzyme E2C	free ubiquitin chain polymerization	Biological process	19822757
HSD3B1	3283	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1	mitochondrial inner membrane	Cellular component	8274411
PTS	5805	6-pyruvoyltetrahydropterin synthase	tetrahydrobiopterin biosynthetic process	Biological process	-
ZIM3	114026	zinc finger, imprinted 3	sequence-specific DNA binding transcription factor activity	Molecular function	-
RORA	6095	RAR-related orphan receptor A	T-helper 17 cell differentiation	Biological process	-
SLC22A5	6584	solute carrier family 22 (organic cation/carnitine transporter), member 5	extracellular exosome	Cellular component	19056867
JUP	3728	junction plakoglobin	protein kinase binding	Molecular function	-
PSPC1	55269	paraspeckle component 1	nuclear matrix	Cellular component	-
RPL23A	6147	ribosomal protein L23a	viral life cycle	Biological process	-
DMRTA1	63951	DMRT-like family A1	transcription, DNA-templated	Biological process	-
RAN	5901	RAN, member RAS oncogene family	protein binding	Molecular function	10353245
ID3	3399	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	microtubule cytoskeleton	Cellular component	-
TMF1	7110	TATA element modulatory factor 1	spermatid nucleus differentiation	Biological process	-
TMEM130	222865	transmembrane protein 130	integral component of membrane	Cellular component	-
NUSAP1	51203	nucleolar and spindle associated protein 1	positive regulation of mitotic nuclear division	Biological process	12963707
ULK2	9706	unc-51 like autophagy activating kinase 2	pre-autophagosomal structure membrane	Cellular component	18936157
OR10K1	391109	olfactory receptor, family 10, subfamily K, member 1	G-protein coupled receptor signaling pathway	Biological process	-
SBNO2	22904	strawberry notch homolog 2 (Drosophila)	bone mineralization	Biological process	-
ELOVL4	6785	ELOVL fatty acid elongase 4	fatty acid biosynthetic process	Biological process	11138005
FCN2	2220	ficolin (collagen/fibrinogen domain containing lectin) 2	opsonization	Biological process	8576206
PHAX	51808	phosphorylated adaptor for RNA export	intracellular membrane-bounded organelle	Cellular component	-
NNMT	4837	nicotinamide N-methyltransferase	response to drug	Biological process	-
GCKR	2646	glucokinase (hexokinase 4) regulator	enzyme binding	Molecular function	-
INPP5D	3635	inositol polyphosphate-5-phosphatase, 145kDa	PTB domain binding	Molecular function	-
KIF2A	3796	kinesin heavy chain member 2A	spindle pole	Cellular component	18411309
AEBP1	165	AE binding protein 1	carboxypeptidase activity	Molecular function	8920928
BCL6	604	B-cell CLL/lymphoma 6	transcription, DNA-templated	Biological process	-
ASUN	55726	asunder spermatogenesis regulator	regulation of mitotic cell cycle	Biological process	15737938
SLX1A	548593	SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)	DNA double-strand break processing involved in repair via single-strand annealing	Biological process	19595721
EGFR	1956	epidermal growth factor receptor	receptor complex	Cellular component	23382219
YWHAG	7532	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma	protein targeting	Biological process	-
DONSON	29980	downstream neighbor of SON	molecular_function	Molecular function	-
DYNLL2	140735	dynein, light chain, LC8-type 2	microtubule	Cellular component	-
ELP3	55140	elongator acetyltransferase complex subunit 3	nucleolus	Cellular component	11714725
RAB29	8934	RAB29, member RAS oncogene family	Golgi to endosome transport	Biological process	-
NCALD	83988	neurocalcin delta	tubulin binding	Molecular function	11964161
COX4I1	1327	cytochrome c oxidase subunit IV isoform 1	nucleus	Cellular component	-
VAMP3	9341	vesicle-associated membrane protein 3	positive regulation of immunoglobulin secretion	Biological process	24055037
NRXN1	9378	neurexin 1	neuroligin family protein binding	Molecular function	-
ALDH9A1	223	aldehyde dehydrogenase 9 family, member A1	amine binding	Molecular function	-
SHANK1	50944	SH3 and multiple ankyrin repeat domains 1	dendritic spine	Cellular component	-
RASGEF1A	221002	RasGEF domain family, member 1A	cell migration	Biological process	17121879
NOP14	8602	NOP14 nucleolar protein	90S preribosome	Cellular component	-
IL25	64806	interleukin 25	eosinophil differentiation	Biological process	-
TP73	7161	tumor protein p73	cell junction	Cellular component	-
PRSS2	5645	protease, serine, 2 (trypsin 2)	positive regulation of cell adhesion	Biological process	12731883
DDX5	1655	DEAD (Asp-Glu-Ala-Asp) box helicase 5	poly(A) RNA binding	Molecular function	22658674
NGFR	4804	nerve growth factor receptor	negative regulation of hair follicle development	Biological process	-
TNIK	23043	TRAF2 and NCK interacting kinase	protein localization to plasma membrane	Biological process	22797597
AKR1C1	1645	aldo-keto reductase family 1, member C1	cellular response to jasmonic acid stimulus	Biological process	19487289
ELAC1	55520	elaC ribonuclease Z 1	tRNA 3'-trailer cleavage, endonucleolytic	Biological process	-
IKZF4	64375	IKAROS family zinc finger 4 (Eos)	metal ion binding	Molecular function	-
PARK2	5071	parkin RBR E3 ubiquitin protein ligase	positive regulation of protein linear polyubiquitination	Biological process	23453807
MT3	4504	metallothionein 3	negative regulation of cysteine-type endopeptidase activity	Biological process	18554677
RGS7	6000	regulator of G-protein signaling 7	G-protein coupled receptor signaling pathway	Biological process	-
A1CF	29974	APOBEC1 complementation factor	apolipoprotein B mRNA editing enzyme complex	Cellular component	10781591
ASIP	434	agouti signaling protein	cell	Cellular component	-
MSH6	2956	mutS homolog 6	somatic recombination of immunoglobulin gene segments	Biological process	-
TECTB	6975	tectorin beta	anchored component of membrane	Cellular component	-
RASSF2	9770	Ras association (RalGDS/AF-6) domain family member 2	nucleus	Cellular component	-
MAF1	84232	MAF1 homolog (S. cerevisiae)	inhibitory synapse	Cellular component	-
TLX1	3195	T-cell leukemia homeobox 1	sequence-specific DNA binding	Molecular function	-
MSRB3	253827	methionine sulfoxide reductase B3	oxidation-reduction process	Biological process	-
HUS1	3364	HUS1 checkpoint homolog (S. pombe)	intra-S DNA damage checkpoint	Biological process	-
HAVCR1	26762	hepatitis A virus cellular receptor 1	virus receptor activity	Molecular function	21536871
MSX1	4487	msh homeobox 1	mammary gland epithelium development	Biological process	-
REPIN1	29803	replication initiator 1	regulation of glucose import in response to insulin stimulus	Biological process	-
MMP11	4320	matrix metallopeptidase 11	extracellular matrix organization	Biological process	-
KRT40	125115	keratin 40, type I	intermediate filament	Cellular component	-
KIF22	3835	kinesin family member 22	nucleus	Cellular component	-
EIF4A3	9775	eukaryotic translation initiation factor 4A3	ATP-dependent RNA helicase activity	Molecular function	10523622
HOMER2	9455	homer scaffolding protein 2	plasma membrane	Cellular component	-
IL25	64806	interleukin 25	response to fungus	Biological process	-
PA2G4	5036	proliferation-associated 2G4, 38kDa	DNA binding	Molecular function	15073182
SNX19	399979	sorting nexin 19	chondrocyte differentiation	Biological process	19877062
SARNP	84324	SAP domain containing ribonucleoprotein	DNA binding	Molecular function	-
TCTN1	79600	tectonic family member 1	neural tube formation	Biological process	-
LOXHD1	125336	lipoxygenase homology domains 1	membrane	Cellular component	-
THBS4	7060	thrombospondin 4	growth factor activity	Molecular function	-
PKNOX1	5316	PBX/knotted 1 homeobox 1	sequence-specific DNA binding transcription factor activity	Molecular function	9143494
ADRB3	155	adrenoceptor beta 3	negative regulation of multicellular organism growth	Biological process	-
SLTM	79811	SAFB-like, transcription modulator	apoptotic process	Biological process	-
ANKRD17	26057	ankyrin repeat domain 17	cytoplasm	Cellular component	-
RNF2	6045	ring finger protein 2	MLL1 complex	Cellular component	15960975
MSL2	55167	male-specific lethal 2 homolog (Drosophila)	MSL complex	Cellular component	20018852
NPFF	8620	neuropeptide FF-amide peptide precursor	regulation of excitatory postsynaptic membrane potential	Biological process	-
CDK20	23552	cyclin-dependent kinase 20	nucleus	Cellular component	-
AP3D1	8943	adaptor-related protein complex 3, delta 1 subunit	melanosome organization	Biological process	22511774
VEGFB	7423	vascular endothelial growth factor B	induction of positive chemotaxis	Biological process	19275959
ANGPT1	284	angiopoietin 1	negative regulation of vascular permeability	Biological process	14978158
CCDC40	55036	coiled-coil domain containing 40	cytoplasm	Cellular component	-
GBA3	57733	glucosidase, beta, acid 3 (gene/pseudogene)	beta-glucosidase activity	Molecular function	17595169
BID	637	BH3 interacting domain death agonist	regulation of G1/S transition of mitotic cell cycle	Biological process	-
CBFA2T3	863	core-binding factor, runt domain, alpha subunit 2; translocated to, 3	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
CXCR1	3577	chemokine (C-X-C motif) receptor 1	dendritic cell chemotaxis	Biological process	16621978
BCHE	590	butyrylcholinesterase	choline binding	Molecular function	-
CDC20	991	cell division cycle 20	cytoplasm	Cellular component	-
MT1G	4495	metallothionein 1G	monocyte activation	Biological process	8119276
DDO	8528	D-aspartate oxidase	aspartate catabolic process	Biological process	9163533
FANCD2	2177	Fanconi anemia, complementation group D2	synapsis	Biological process	-
NAT10	55226	N-acetyltransferase 10 (GCN5-related)	membrane	Cellular component	19946888
ADRA1A	148	adrenoceptor alpha 1A	nucleus	Cellular component	22120526
TNFSF13	8741	tumor necrosis factor (ligand) superfamily, member 13	extracellular exosome	Cellular component	19199708
CYSLTR1	10800	cysteinyl leukotriene receptor 1	leukotriene receptor activity	Molecular function	-
PTPN3	5774	protein tyrosine phosphatase, non-receptor type 3	peptidyl-tyrosine dephosphorylation	Biological process	1648725
MAN2B2	23324	mannosidase, alpha, class 2B, member 2	extracellular exosome	Cellular component	23376485
POU2F1	5451	POU class 2 homeobox 1	sequence-specific DNA binding transcription factor activity	Molecular function	2341156
PRKAA1	5562	protein kinase, AMP-activated, alpha 1 catalytic subunit	cellular response to hydrogen peroxide	Biological process	-
ZBTB32	27033	zinc finger and BTB domain containing 32	nuclear chromosome	Cellular component	-
ALS2CL	259173	ALS2 C-terminal like	Rab GTPase binding	Molecular function	-
NEIL3	55247	nei endonuclease VIII-like 3 (E. coli)	DNA-(apurinic or apyrimidinic site) lyase activity	Molecular function	19170771
OR8H2	390151	olfactory receptor, family 8, subfamily H, member 2	odorant binding	Molecular function	-
POLQ	10721	polymerase (DNA directed), theta	DNA repair	Biological process	10395804
OPTN	10133	optineurin	regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	-
COX17	10063	COX17 cytochrome c oxidase copper chaperone	brain development	Biological process	-
CAMK2D	817	calcium/calmodulin-dependent protein kinase II delta	regulation of heart rate by cardiac conduction	Biological process	22514276
MYNN	55892	myoneurin	zinc ion binding	Molecular function	10873615
CAMK1G	57172	calcium/calmodulin-dependent protein kinase IG	calmodulin binding	Molecular function	-
TUBE1	51175	tubulin, epsilon 1	metabolic process	Biological process	-
TNNI3	7137	troponin I type 3 (cardiac)	troponin C binding	Molecular function	11735257
OR4D10	390197	olfactory receptor, family 4, subfamily D, member 10	integral component of membrane	Cellular component	-
APOC2	344	apolipoprotein C-II	chylomicron	Cellular component	8245722
VASH1	22846	vasohibin 1	cytoplasm	Cellular component	15467828
TWIST1	7291	twist family bHLH transcription factor 1	negative regulation of sequence-specific DNA binding transcription factor activity	Biological process	-
PIK3CA	5290	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	phosphatidylinositol 3-kinase signaling	Biological process	-
TCEB3CL	728929	transcription elongation factor B polypeptide 3C-like	transcription, DNA-templated	Biological process	-
VDAC2	7417	voltage-dependent anion channel 2	mitochondrial outer membrane	Cellular component	-
TBP	6908	TATA box binding protein	transcription factor binding	Molecular function	11005381
AMOT	154796	angiomotin	negative regulation of angiogenesis	Biological process	11257124
OR52E5	390082	olfactory receptor, family 52, subfamily E, member 5	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
SOX2	6657	SRY (sex determining region Y)-box 2	pituitary gland development	Biological process	18285410
SMAD5	4090	SMAD family member 5	signal transduction	Biological process	9759503
PRKG2	5593	protein kinase, cGMP-dependent, type II	small molecule metabolic process	Biological process	-
SCN1A	6323	sodium channel, voltage gated, type I alpha subunit	neuronal action potential	Biological process	-
TFDP1	7027	transcription factor Dp-1	mitotic cell cycle	Biological process	-
ATP2C1	27032	ATPase, Ca++ transporting, type 2C, member 1	Golgi apparatus	Cellular component	11741891
ZSWIM6	57688	zinc finger, SWIM-type containing 6	zinc ion binding	Molecular function	-
CCNG1	900	cyclin G1	regulation of cyclin-dependent protein serine/threonine kinase activity	Biological process	8626390
STXBP4	252983	syntaxin binding protein 4	intermediate filament cytoskeleton	Cellular component	-
HIPK2	28996	homeodomain interacting protein kinase 2	RNA polymerase II transcription coactivator activity	Molecular function	-
RALB	5899	v-ral simian leukemia viral oncogene homolog B	ATPase binding	Molecular function	24056301
ID2	3398	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	negative regulation of osteoblast differentiation	Biological process	-
SHROOM4	57477	shroom family member 4	filamentous actin	Cellular component	16249884
NRCAM	4897	neuronal cell adhesion molecule	heterotypic cell-cell adhesion	Biological process	-
SLC30A6	55676	solute carrier family 30 (zinc transporter), member 6	cellular protein metabolic process	Biological process	-
CDH2	1000	cadherin 2, type 1, N-cadherin (neuronal)	adherens junction organization	Biological process	-
EEF2K	29904	eukaryotic elongation factor 2 kinase	protein kinase activity	Molecular function	9144159
CYP2R1	120227	cytochrome P450, family 2, subfamily R, polypeptide 1	endoplasmic reticulum membrane	Cellular component	-
ARIH1	25820	ariadne RBR E3 ubiquitin protein ligase 1	cytoplasm	Cellular component	11278816
TAS2R40	259286	taste receptor, type 2, member 40	integral component of membrane	Cellular component	20022913
GNAO1	2775	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O	response to morphine	Biological process	-
DYNC1I1	1780	dynein, cytoplasmic 1, intermediate chain 1	cytosol	Cellular component	-
ATF2	1386	activating transcription factor 2	sequence-specific DNA binding transcription factor activity	Molecular function	8798441
PDE7B	27115	phosphodiesterase 7B	signal transduction	Biological process	-
ECT2	1894	epithelial cell transforming 2	cytokinesis	Biological process	16236794
GNAQ	2776	guanine nucleotide binding protein (G protein), q polypeptide	signal transducer activity	Molecular function	-
SLITRK2	84631	SLIT and NTRK-like family, member 2	axonogenesis	Biological process	-
CYP4A11	1579	cytochrome P450, family 4, subfamily A, polypeptide 11	heme binding	Molecular function	-
HOXA13	3209	homeobox A13	endothelial cell fate specification	Biological process	-
ART5	116969	ADP-ribosyltransferase 5	NAD+ nucleosidase activity	Molecular function	-
NUAK2	81788	NUAK family, SNF1-like kinase, 2	negative regulation of TOR signaling	Biological process	-
BAHD1	22893	bromo adjacent homology domain containing 1	heterochromatin assembly	Biological process	19666599
AP1S1	1174	adaptor-related protein complex 1, sigma 1 subunit	AP-1 adaptor complex	Cellular component	9733768
GTF2H1	2965	general transcription factor IIH, polypeptide 1, 62kDa	nucleoplasm	Cellular component	-
RAB5A	5868	RAB5A, member RAS oncogene family	GDP binding	Molecular function	15378032
SERP1	27230	stress-associated endoplasmic reticulum protein 1	muscle organ morphogenesis	Biological process	-
MAPKAP1	79109	mitogen-activated protein kinase associated protein 1	plasma membrane	Cellular component	17303383
MAK16	84549	MAK16 homolog (S. cerevisiae)	intracellular membrane-bounded organelle	Cellular component	-
OR2W1	26692	olfactory receptor, family 2, subfamily W, member 1	G-protein coupled receptor activity	Molecular function	-
NR1H4	9971	nuclear receptor subfamily 1, group H, member 4	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
ZP2	7783	zona pellucida glycoprotein 2 (sperm receptor)	regulation of acrosome reaction	Biological process	11751269
APRT	353	adenine phosphoribosyltransferase	AMP salvage	Biological process	-
PSMA6	5687	proteasome (prosome, macropain) subunit, alpha type, 6	proteasomal ubiquitin-independent protein catabolic process	Biological process	-
SKAP1	8631	src kinase associated phosphoprotein 1	positive regulation of transcription, DNA-templated	Biological process	11909961
ERCC2	2068	excision repair cross-complementation group 2	transcription elongation from RNA polymerase II promoter	Biological process	-
IFT20	90410	intraflagellar transport 20	centrosome localization	Biological process	-
ACACA	31	acetyl-CoA carboxylase alpha	protein binding	Molecular function	16326698
DUSP1	1843	dual specificity phosphatase 1	endoderm formation	Biological process	-
RTN3	10313	reticulon 3	extracellular space	Cellular component	10331947
TMEM192	201931	transmembrane protein 192	nucleus	Cellular component	22736246
YWHAE	7531	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon	programmed cell death	Biological process	-
ZRSR1	7310	zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1	nucleus	Cellular component	-
SPAST	6683	spastin	metabolic process	Biological process	-
ADH5	128	alcohol dehydrogenase 5 (class III), chi polypeptide	aging	Biological process	-
HDAC8	55869	histone deacetylase 8	chromatin modification	Biological process	12711221
RAB3B	5865	RAB3B, member RAS oncogene family	protein binding	Molecular function	24891604
MAT2A	4144	methionine adenosyltransferase II, alpha	cytosol	Cellular component	-
ACOT8	10005	acyl-CoA thioesterase 8	receptor binding	Molecular function	20178365
FADD	8772	Fas (TNFRSF6)-associated via death domain	cytosol	Cellular component	-
CDC42EP5	148170	CDC42 effector protein (Rho GTPase binding) 5	Rho protein signal transduction	Biological process	-
BACE1	23621	beta-site APP-cleaving enzyme 1	plasma membrane	Cellular component	24612608
FUOM	282969	fucose mutarotase	fucose binding	Molecular function	-
REL	5966	v-rel avian reticuloendotheliosis viral oncogene homolog	positive regulation of transcription from RNA polymerase II promoter	Biological process	1406630
CHEK1	1111	checkpoint kinase 1	regulation of mitotic centrosome separation	Biological process	15311285
DUSP7	1849	dual specificity phosphatase 7	MAP kinase tyrosine/serine/threonine phosphatase activity	Molecular function	9788880
PIWIL4	143689	piwi-like RNA-mediated gene silencing 4	piP-body	Cellular component	-
NBL1	4681	neuroblastoma 1, DAN family BMP antagonist	positive regulation of neuron differentiation	Biological process	-
SPRR2F	6705	small proline-rich protein 2F	epidermis development	Biological process	8325635
TMBIM4	51643	transmembrane BAX inhibitor motif containing 4	negative regulation of apoptotic process	Biological process	17319741
IL20RB	53833	interleukin 20 receptor beta	homeostasis of number of cells within a tissue	Biological process	-
PRKCD	5580	protein kinase C, delta	negative regulation of protein binding	Biological process	14583092
CCL16	6360	chemokine (C-C motif) ligand 16	inflammatory response	Biological process	-
NOTCH2	4853	notch 2	pulmonary valve morphogenesis	Biological process	16773578
MTMR6	9107	myotubularin related protein 6	calcium-activated potassium channel activity	Molecular function	15831468
GTF2H3	2967	general transcription factor IIH, polypeptide 3, 34kDa	termination of RNA polymerase I transcription	Biological process	-
LEF1	51176	lymphoid enhancer-binding factor 1	forebrain radial glial cell differentiation	Biological process	-
SAE1	10055	SUMO1 activating enzyme subunit 1	nucleoplasm	Cellular component	-
CECR1	51816	cat eye syndrome chromosome region, candidate 1	zinc ion binding	Molecular function	20147294
PDCL	5082	phosducin-like	protein binding	Molecular function	21516116
CTH	1491	cystathionine gamma-lyase	nucleoplasm	Cellular component	-
LPIN1	23175	lipin 1	ruffle organization	Biological process	-
APOF	319	apolipoprotein F	triglyceride metabolic process	Biological process	-
PRNP	5621	prion protein	nucleus	Cellular component	-
RNF44	22838	ring finger protein 44	zinc ion binding	Molecular function	-
RAB27B	5874	RAB27B, member RAS oncogene family	Rab protein signal transduction	Biological process	-
TAL2	6887	T-cell acute lymphocytic leukemia 2	protein dimerization activity	Molecular function	-
DRD5	1816	dopamine receptor D5	cellular response to catecholamine stimulus	Biological process	18403039
ASS1	445	argininosuccinate synthase 1	cellular response to tumor necrosis factor	Biological process	-
IRF7	3665	interferon regulatory factor 7	transcription from RNA polymerase II promoter	Biological process	-
ATAD5	79915	ATPase family, AAA domain containing 5	ATP binding	Molecular function	-
TACC3	10460	transforming, acidic coiled-coil containing protein 3	cerebral cortex development	Biological process	-
SAA4	6291	serum amyloid A4, constitutive	cell chemotaxis	Biological process	-
CRYM	1428	crystallin, mu	oxidation-reduction process	Biological process	-
TIMP2	7077	TIMP metallopeptidase inhibitor 2	negative regulation of metalloenzyme activity	Biological process	-
TLR4	7099	toll-like receptor 4	positive regulation of interleukin-6 production	Biological process	19740627
CUBN	8029	cubilin (intrinsic factor-cobalamin receptor)	calcium ion binding	Molecular function	-
ACADVL	37	acyl-CoA dehydrogenase, very long chain	regulation of cholesterol metabolic process	Biological process	-
ADORA2A	135	adenosine A2a receptor	negative regulation of neuron apoptotic process	Biological process	-
GRK4	2868	G protein-coupled receptor kinase 4	cytosol	Cellular component	-
DAPK2	23604	death-associated protein kinase 2	protein binding	Molecular function	21408167
LRP6	4040	low density lipoprotein receptor-related protein 6	dopaminergic neuron differentiation	Biological process	-
SHANK2	22941	SH3 and multiple ankyrin repeat domains 2	long term synaptic depression	Biological process	22699620
GRHL3	57822	grainyhead-like 3 (Drosophila)	wound healing	Biological process	-
MTMR7	9108	myotubularin related protein 7	protein dephosphorylation	Biological process	9736772
HYAL3	8372	hyaluronoglucosaminidase 3	inflammatory response	Biological process	18390475
DUSP3	1845	dual specificity phosphatase 3	toll-like receptor 9 signaling pathway	Biological process	-
CLGN	1047	calmegin	protein complex assembly	Biological process	-
ALKBH7	84266	alkB, alkylation repair homolog 7 (E. coli)	mitochondrial matrix	Cellular component	23666923
CD226	10666	CD226 molecule	cell adhesion	Biological process	-
MYO7A	4647	myosin VIIA	lysosome organization	Biological process	16001398
ADGRB2	576	adhesion G protein-coupled receptor B2	negative regulation of angiogenesis	Biological process	-
HAND2	9464	heart and neural crest derivatives expressed 2	suckling behavior	Biological process	-
ACSL6	23305	acyl-CoA synthetase long-chain family member 6	long-chain fatty-acyl-CoA biosynthetic process	Biological process	-
KIFC3	3801	kinesin family member C3	visual perception	Biological process	9782090
LLGL1	3996	lethal giant larvae homolog 1 (Drosophila)	trans-Golgi network membrane	Cellular component	-
SPESP1	246777	sperm equatorial segment protein 1	acrosomal vesicle	Cellular component	-
PVRL2	5819	poliovirus receptor-related 2 (herpesvirus entry mediator B)	susceptibility to natural killer cell mediated cytotoxicity	Biological process	12913096
PRLH	51052	prolactin releasing hormone	response to insulin	Biological process	-
Sep-11	55752	septin 11	stress fiber	Cellular component	15485874
HRG	3273	histidine-rich glycoprotein	positive regulation of apoptotic process	Biological process	14744774
SIRPA	140885	signal-regulatory protein alpha	SH3 domain binding	Molecular function	-
TARDBP	23435	TAR DNA binding protein	protein binding	Molecular function	20740007
APC	324	adenomatous polyposis coli	bicellular tight junction assembly	Biological process	18502210
OTOP1	133060	otopetrin 1	detection of gravity	Biological process	-
CNOT2	4848	CCR4-NOT transcription complex, subunit 2	transcription from RNA polymerase II promoter	Biological process	10637334
OR7C2	26658	olfactory receptor, family 7, subfamily C, member 2	plasma membrane	Cellular component	-
TPSAB1	7177	tryptase alpha/beta 1	extracellular space	Cellular component	20551380
TRPV1	7442	transient receptor potential cation channel, subfamily V, member 1	ion transmembrane transport	Biological process	-
SHB	6461	Src homology 2 domain containing adaptor protein B	positive regulation of signal transduction	Biological process	8302579
STAR	6770	steroidogenic acute regulatory protein	insecticide metabolic process	Biological process	-
RLTPR	146206	RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing	establishment of protein localization	Biological process	-
E2F5	1875	E2F transcription factor 5, p130-binding	transcription, DNA-templated	Biological process	-
DLX5	1749	distal-less homeobox 5	positive regulation of canonical Wnt signaling pathway	Biological process	-
ATP6V0E1	8992	ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1	cellular iron ion homeostasis	Biological process	-
PRPF8	10594	pre-mRNA processing factor 8	pre-mRNA intronic binding	Molecular function	-
KISS1R	84634	KISS1 receptor	neuropeptide signaling pathway	Biological process	11387329
CD2AP	23607	CD2-associated protein	ruffle	Cellular component	10339567
ZFAND6	54469	zinc finger, AN1-type domain 6	molecular_function	Molecular function	-
ITGA2	3673	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	collagen binding	Molecular function	11518510
XRCC4	7518	X-ray repair complementing defective repair in Chinese hamster cells 4	DNA ligase IV complex	Cellular component	9242410
ST8SIA1	6489	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1	protein N-linked glycosylation via asparagine	Biological process	-
DVL1	1855	dishevelled segment polarity protein 1	axon extension	Biological process	-
LAT	27040	linker for activation of T cells	calcium-mediated signaling	Biological process	12646565
NOG	9241	noggin	pituitary gland development	Biological process	-
KLF4	9314	Kruppel-like factor 4 (gut)	negative regulation of transcription from RNA polymerase II promoter	Biological process	20551324
APOE	348	apolipoprotein E	negative regulation of neuron apoptotic process	Biological process	-
PARP1	142	poly (ADP-ribose) polymerase 1	membrane	Cellular component	19946888
WDFY3	23001	WD repeat and FYVE domain containing 3	extrinsic component of autophagosome membrane	Cellular component	-
HSD17B11	51170	hydroxysteroid (17-beta) dehydrogenase 11	steroid dehydrogenase activity	Molecular function	12697717
FRG1	2483	FSHD region gene 1	mRNA splicing, via spliceosome	Biological process	11991638
HIST2H4B	554313	histone cluster 2, H4b	negative regulation of megakaryocyte differentiation	Biological process	18474616
GPC4	2239	glypican 4	nucleus	Cellular component	21630459
ZCCHC5	203430	zinc finger, CCHC domain containing 5	nucleic acid binding	Molecular function	-
CATSPER3	347732	cation channel, sperm associated 3	multicellular organism reproduction	Biological process	-
KCNK18	338567	potassium channel, two pore domain subfamily K, member 18	plasma membrane	Cellular component	-
VAMP7	6845	vesicle-associated membrane protein 7	lysosomal membrane	Cellular component	-
VAMP4	8674	vesicle-associated membrane protein 4	endosome	Cellular component	9553086
FBXL7	23194	F-box and leucine-rich repeat protein 7	ubiquitin-protein transferase activity	Molecular function	10531035
ALOX15	246	arachidonate 15-lipoxygenase	bone mineralization	Biological process	-
KIF17	57576	kinesin family member 17	axoneme	Cellular component	-
IFNA13	3447	interferon, alpha 13	extracellular region	Cellular component	-
IDO1	3620	indoleamine 2,3-dioxygenase 1	tryptophan catabolic process to kynurenine	Biological process	-
NRCAM	4897	neuronal cell adhesion molecule	clustering of voltage-gated sodium channels	Biological process	14602817
PYCARD	29108	PYD and CARD domain containing	protein binding	Molecular function	11786556
GDF3	9573	growth differentiation factor 3	endoderm development	Biological process	-
TNFRSF21	27242	tumor necrosis factor receptor superfamily, member 21	regulation of oligodendrocyte differentiation	Biological process	-
UBXN6	80700	UBX domain protein 6	nucleus	Cellular component	-
PTGES2	80142	prostaglandin E synthase 2	lyase activity	Molecular function	-
NFATC4	4776	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	muscle cell development	Biological process	-
ATP5H	10476	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d	mitochondrial inner membrane	Cellular component	-
MAPK14	1432	mitogen-activated protein kinase 14	toll-like receptor 10 signaling pathway	Biological process	-
IMMT	10989	inner membrane protein, mitochondrial	mitochondrial calcium ion homeostasis	Biological process	-
ERLIN2	11160	ER lipid raft associated 2	protein binding	Molecular function	19240031
FGFR3	2261	fibroblast growth factor receptor 3	substantia nigra development	Biological process	-
DPEP3	64180	dipeptidase 3	metal ion binding	Molecular function	-
CD1A	909	CD1a molecule	antigen processing and presentation, exogenous lipid antigen via MHC class Ib	Biological process	-
CXCR3	2833	chemokine (C-X-C motif) receptor 3	regulation of leukocyte migration	Biological process	-
DNMT3B	1789	DNA (cytosine-5-)-methyltransferase 3 beta	intracellular membrane-bounded organelle	Cellular component	-
FXYD6	53826	FXYD domain containing ion transport regulator 6	regulation of sodium ion transmembrane transporter activity	Biological process	-
ACOT2	10965	acyl-CoA thioesterase 2	long-chain fatty acid metabolic process	Biological process	16940157
LRRC3	81543	leucine rich repeat containing 3	integral component of membrane	Cellular component	-
PRNP	5621	prion protein	Golgi apparatus	Cellular component	-
CEMIP	57214	cell migration inducing protein, hyaluronan binding	ER retention sequence binding	Molecular function	23990668
IL12A	3592	interleukin 12A	interleukin-12 complex	Cellular component	14718574
CHRM2	1129	cholinergic receptor, muscarinic 2	synapse	Cellular component	-
CLSPN	63967	claspin	peptidyl-serine phosphorylation	Biological process	16885022
CDC42	998	cell division cycle 42	mitogen-activated protein kinase kinase kinase binding	Molecular function	-
SLCO1B3	28234	solute carrier organic anion transporter family, member 1B3	transmembrane transport	Biological process	-
FREM3	166752	FRAS1 related extracellular matrix 3	basement membrane	Cellular component	-
LMO4	8543	LIM domain only 4	enhancer sequence-specific DNA binding	Molecular function	-
SNX25	83891	sorting nexin 25	negative regulation of pathway-restricted SMAD protein phosphorylation	Biological process	21266196
IL3	3562	interleukin 3	positive regulation of tyrosine phosphorylation of Stat5 protein	Biological process	9722506
NCOA1	8648	nuclear receptor coactivator 1	positive regulation of female receptivity	Biological process	-
PSMC2	5701	proteasome (prosome, macropain) 26S subunit, ATPase, 2	TBP-class protein binding	Molecular function	-
UGCG	7357	UDP-glucose ceramide glucosyltransferase	small molecule metabolic process	Biological process	-
PCNA	5111	proliferating cell nuclear antigen	DNA replication factor C complex	Cellular component	2565339
FGF13	2258	fibroblast growth factor 13	nucleus	Cellular component	8790420
SCN4B	6330	sodium channel, voltage gated, type IV beta subunit	sodium ion transmembrane transport	Biological process	20226894
ULK4	54986	unc-51 like kinase 4	regulation of neuron projection development	Biological process	24284070
WNT7A	7476	wingless-type MMTV integration site family, member 7A	sex differentiation	Biological process	9790192
ULK1	8408	unc-51 like autophagy activating kinase 1	protein serine/threonine kinase activity	Molecular function	9693035
CCDC151	115948	coiled-coil domain containing 151	cilium	Cellular component	-
CYP27A1	1593	cytochrome P450, family 27, subfamily A, polypeptide 1	bile acid metabolic process	Biological process	-
PHIP	55023	pleckstrin homology domain interacting protein	regulation of growth	Biological process	-
POLI	11201	polymerase (DNA directed) iota	intracellular membrane-bounded organelle	Cellular component	-
CSF3	1440	colony stimulating factor 3 (granulocyte)	positive regulation of protein kinase B signaling	Biological process	23001182
CTSK	1513	cathepsin K	endolysosome lumen	Cellular component	-
SMC1A	8243	structural maintenance of chromosomes 1A	post-translational protein modification	Biological process	-
MDH1	4190	malate dehydrogenase 1, NAD (soluble)	gluconeogenesis	Biological process	-
IMPDH2	3615	IMP (inosine 5'-monophosphate) dehydrogenase 2	purine ribonucleoside monophosphate biosynthetic process	Biological process	-
ALDH18A1	5832	aldehyde dehydrogenase 18 family, member A1	mitochondrial inner membrane	Cellular component	-
EIF5AL1	143244	eukaryotic translation initiation factor 5A-like 1	ribosome binding	Molecular function	-
PRPF8	10594	pre-mRNA processing factor 8	second spliceosomal transesterification activity	Molecular function	-
SLTM	79811	SAFB-like, transcription modulator	poly(A) RNA binding	Molecular function	22658674
P3H4	10609	prolyl 3-hydroxylase family member 4 (non-enzymatic)	condensed nuclear chromosome	Cellular component	8862517
MMD	23531	monocyte to macrophage differentiation-associated	lysosomal membrane	Cellular component	-
CASK	8573	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	negative regulation of cellular response to growth factor stimulus	Biological process	18664494
SUN5	140732	Sad1 and UNC84 domain containing 5	integral component of membrane	Cellular component	-
PRKX	5613	protein kinase, X-linked	cytoplasm	Cellular component	10026146
PPP1R1C	151242	protein phosphatase 1, regulatory (inhibitor) subunit 1C	cytoplasm	Cellular component	-
UGT3A1	133688	UDP glycosyltransferase 3 family, polypeptide A1	cellular response to hormone stimulus	Biological process	-
ARID1B	57492	AT rich interactive domain 1B (SWI1-like)	DNA binding	Molecular function	-
UBXN11	91544	UBX domain protein 11	cytoplasm	Cellular component	-
FCER1G	2207	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	serotonin secretion by platelet	Biological process	-
RPA2	6118	replication protein A2, 32kDa	regulation of cellular response to heat	Biological process	-
Sep-10	151011	septin 10	cell division	Biological process	-
GLRA1	2741	glycine receptor, alpha 1	chloride transmembrane transport	Biological process	7920629
LAMP2	3920	lysosomal-associated membrane protein 2	enzyme binding	Molecular function	22641697
GRK1	6011	G protein-coupled receptor kinase 1	photoreceptor cell morphogenesis	Biological process	-
COL25A1	84570	collagen, type XXV, alpha 1	collagen trimer	Cellular component	-
LOC100133495	100133495	HERV-K_11q22.1 provirus ancestral Pol protein [Includes: Reverse transcriptase	RNA-directed DNA polymerase activity	Molecular function	-
SWAP70	23075	SWAP switching B-cell complex 70kDa subunit	ATP binding	Molecular function	-
DSG1	1828	desmoglein 1	cell-cell junction	Cellular component	7983064
OGT	8473	O-linked N-acetylglucosamine (GlcNAc) transferase	histone H3-K4 trimethylation	Biological process	23353889
SUPT16H	11198	suppressor of Ty 16 homolog (S. cerevisiae)	nucleoplasm	Cellular component	-
RPL9	6133	ribosomal protein L9	translational termination	Biological process	-
GTF2E1	2960	general transcription factor IIE, polypeptide 1, alpha 56kDa	sequence-specific DNA binding	Molecular function	-
ATP11B	23200	ATPase, class VI, type 11B	membrane	Cellular component	19946888
TRPC4	7223	transient receptor potential cation channel, subfamily C, member 4	oligodendrocyte differentiation	Biological process	-
PLOD2	5352	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2	extracellular exosome	Cellular component	19199708
HIST1H3D	8351	histone cluster 1, H3d	chromatin silencing at rDNA	Biological process	-
GRB2	2885	growth factor receptor-bound protein 2	cytoplasm	Cellular component	21179510
DRD2	1813	dopamine receptor D2	long-term memory	Biological process	-
ZNF658B	401509	zinc finger protein 658B, pseudogene	regulation of transcription, DNA-templated	Biological process	-
CASP8	841	caspase 8, apoptosis-related cysteine peptidase	execution phase of apoptosis	Biological process	21737330
MTPN	136319	myotrophin	positive regulation of macromolecule biosynthetic process	Biological process	-
HINFP	25988	histone H4 transcription factor	DNA binding	Molecular function	18850719
SPIN1	10927	spindlin 1	nucleus	Cellular component	-
KIF14	9928	kinesin family member 14	microtubule motor activity	Molecular function	-
PDCD2	5134	programmed cell death 2	enzyme binding	Molecular function	23382074
XBP1	7494	X-box binding protein 1	cholesterol homeostasis	Biological process	-
YWHAZ	7534	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta	extracellular exosome	Cellular component	19056867
C4BPB	725	complement component 4 binding protein, beta	innate immune response	Biological process	-
PVR	5817	poliovirus receptor	plasma membrane	Cellular component	-
CCND1	595	cyclin D1	Leydig cell differentiation	Biological process	-
IL1RAP	3556	interleukin 1 receptor accessory protein	integral component of plasma membrane	Cellular component	7775431
TCF7L2	6934	transcription factor 7-like 2 (T-cell specific, HMG-box)	sequence-specific DNA binding	Molecular function	16532032
MRPL23	6150	mitochondrial ribosomal protein L23	mitochondrial translational elongation	Biological process	-
PSMB7	5695	proteasome (prosome, macropain) subunit, beta type, 7	threonine-type endopeptidase activity	Molecular function	-
A2M	2	alpha-2-macroglobulin	enzyme binding	Molecular function	11435418
HTRA4	203100	HtrA serine peptidase 4	endopeptidase activity	Molecular function	18387192
UQCRQ	27089	ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa	ubiquinol-cytochrome-c reductase activity	Molecular function	-
DOC2A	8448	double C2-like domains, alpha	lysosome	Cellular component	-
SERPINE1	5054	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	transforming growth factor beta receptor signaling pathway	Biological process	-
ING2	3622	inhibitor of growth family, member 2	spermatid development	Biological process	21124965
DAGLA	747	diacylglycerol lipase, alpha	arachidonic acid metabolic process	Biological process	14610053
ETV2	2116	ets variant 2	regulation of transcription from RNA polymerase II promoter	Biological process	-
FRS2	10818	fibroblast growth factor receptor substrate 2	prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis	Biological process	-
IPO7	10527	importin 7	signal transduction	Biological process	9214382
UTP14C	9724	UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)	cell differentiation	Biological process	-
STAT5B	6777	signal transducer and activator of transcription 5B	prolactin signaling pathway	Biological process	-
BBS1	582	Bardet-Biedl syndrome 1	RNA polymerase II repressing transcription factor binding	Molecular function	22302990
TBC1D14	57533	TBC1 domain family, member 14	negative regulation of autophagy	Biological process	22613832
BGLAP	632	bone gamma-carboxyglutamate (gla) protein	cell aging	Biological process	-
PAK2	5062	p21 protein (Cdc42/Rac)-activated kinase 2	activation of protein kinase activity	Biological process	-
SOX14	8403	SRY (sex determining region Y)-box 14	nervous system development	Biological process	9925951
GRM1	2911	glutamate receptor, metabotropic 1	regulation of synaptic transmission, glutamatergic	Biological process	-
MYO1D	4642	myosin ID	calcium-dependent protein binding	Molecular function	-
TACR3	6870	tachykinin receptor 3	integral component of plasma membrane	Cellular component	1374246
RGCC	28984	regulator of cell cycle	nucleus	Cellular component	11687586
GNAT1	2779	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1	regulation of rhodopsin mediated signaling pathway	Biological process	-
ME1	4199	malic enzyme 1, NADP(+)-dependent, cytosolic	small molecule metabolic process	Biological process	-
SERPINA1	5265	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1	serine-type endopeptidase inhibitor activity	Molecular function	12878203
HERPUD1	9709	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	positive regulation of ER-associated ubiquitin-dependent protein catabolic process	Biological process	18307982
NSMCE2	286053	non-SMC element 2, MMS21 homolog (S. cerevisiae)	positive regulation of maintenance of mitotic sister chromatid cohesion	Biological process	19502785
METTL21A	151194	methyltransferase like 21A	cytoplasm	Cellular component	-
DNAJA1	3301	DnaJ (Hsp40) homolog, subfamily A, member 1	negative regulation of protein ubiquitination	Biological process	12150907
PECAM1	5175	platelet/endothelial cell adhesion molecule 1	signal transduction	Biological process	7994021
GJA3	2700	gap junction protein, alpha 3, 46kDa	visual perception	Biological process	10205266
KLF9	687	Kruppel-like factor 9	plasma membrane	Cellular component	-
GJD4	219770	gap junction protein, delta 4, 40.1kDa	connexon complex	Cellular component	-
CFI	3426	complement factor I	membrane	Cellular component	-
EMILIN1	11117	elastin microfibril interfacer 1	extracellular matrix organization	Biological process	-
MTCH2	23788	mitochondrial carrier 2	integral component of membrane	Cellular component	-
RIBC2	26150	RIB43A domain with coiled-coils 2	nucleus	Cellular component	21630459
EPS15	2060	epidermal growth factor receptor pathway substrate 15	cytosol	Cellular component	-
RORB	6096	RAR-related orphan receptor B	cellular response to retinoic acid	Biological process	-
POMT1	10585	protein-O-mannosyltransferase 1	endoplasmic reticulum membrane	Cellular component	14699049
DDX3Y	8653	DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked	chromosome segregation	Biological process	-
UBE2C	11065	ubiquitin-conjugating enzyme E2C	mitotic spindle assembly checkpoint	Biological process	-
NR2E3	10002	nuclear receptor subfamily 2, group E, member 3	gene expression	Biological process	-
UMPS	7372	uridine monophosphate synthetase	small molecule metabolic process	Biological process	-
RAMP2	10266	receptor (G protein-coupled) activity modifying protein 2	positive regulation of vasculogenesis	Biological process	-
NPPC	4880	natriuretic peptide C	secretory granule	Cellular component	-
NDUFB4	4710	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa	integral component of membrane	Cellular component	-
PLEC	5339	plectin	sarcoplasm	Cellular component	21223964
GALNT8	26290	polypeptide N-acetylgalactosaminyltransferase 8	protein O-linked glycosylation	Biological process	-
CENPE	1062	centromere protein E, 312kDa	metabolic process	Biological process	7889940
MAPK7	5598	mitogen-activated protein kinase 7	cellular response to transforming growth factor beta stimulus	Biological process	18588859
PIK3R2	5296	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	1-phosphatidylinositol-3-kinase activity	Molecular function	-
DEFB115	245929	defensin, beta 115	defense response to bacterium	Biological process	-
GATA3	2625	GATA binding protein 3	nucleoplasm	Cellular component	-
C10orf111	221060	chromosome 10 open reading frame 111	integral component of membrane	Cellular component	-
PDCD11	22984	programmed cell death 11	mRNA processing	Biological process	-
OR4F4	26682	olfactory receptor, family 4, subfamily F, member 4	transmembrane signaling receptor activity	Molecular function	-
FADD	8772	Fas (TNFRSF6)-associated via death domain	negative regulation of necroptotic process	Biological process	-
BTK	695	Bruton agammaglobulinemia tyrosine kinase	receptor binding	Molecular function	-
HSP90AB2P	391634	heat shock protein 90kDa alpha (cytosolic), class B member 2, pseudogene	biological_process	Biological process	-
OR10G9	219870	olfactory receptor, family 10, subfamily G, member 9	integral component of membrane	Cellular component	-
MAPKAPK2	9261	mitogen-activated protein kinase-activated protein kinase 2	centrosome	Cellular component	-
RAB5A	5868	RAB5A, member RAS oncogene family	endocytic vesicle	Cellular component	-
KCNMB3	27094	potassium channel subfamily M regulatory beta subunit 3	detection of calcium ion	Biological process	10692449
SPRR2E	6704	small proline-rich protein 2E	epidermis development	Biological process	8325635
TSHZ2	128553	teashirt zinc finger homeobox 2	transcription, DNA-templated	Biological process	-
KCNH3	23416	potassium channel, voltage gated eag related subfamily H, member 3	regulation of ion transmembrane transport	Biological process	-
SEC31A	22872	SEC31 homolog A (S. cerevisiae)	endoplasmic reticulum unfolded protein response	Biological process	-
ANG	283	angiogenin, ribonuclease, RNase A family, 5	activation of protein kinase B activity	Biological process	17125737
PAX3	5077	paired box 3	spinal cord association neuron differentiation	Biological process	-
CD79A	973	CD79a molecule, immunoglobulin-associated alpha	protein binding	Molecular function	25416956
PHB2	11331	prohibitin 2	estrogen receptor binding	Molecular function	10359819
TP53I11	9537	tumor protein p53 inducible protein 11	negative regulation of cell proliferation	Biological process	9305847
TAS2R9	50835	taste receptor, type 2, member 9	G-protein coupled receptor signaling pathway	Biological process	-
SLC25A46	91137	solute carrier family 25, member 46	biological_process	Biological process	-
MAP2K1	5604	mitogen-activated protein kinase kinase 1	MyD88-dependent toll-like receptor signaling pathway	Biological process	-
RPP14	11102	ribonuclease P/MRP 14kDa subunit	ribonuclease P activity	Molecular function	-
AKAP7	9465	A kinase (PRKA) anchor protein 7	plasma membrane	Cellular component	10613906
HERPUD1	9709	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	endoplasmic reticulum unfolded protein response	Biological process	-
SEC61G	23480	Sec61 gamma subunit	IRE1-mediated unfolded protein response	Biological process	-
ZNF879	345462	zinc finger protein 879	transcription, DNA-templated	Biological process	-
HES7	84667	hes family bHLH transcription factor 7	transcription, DNA-templated	Biological process	-
PLAU	5328	plasminogen activator, urokinase	blood coagulation	Biological process	-
NTSR1	4923	neurotensin receptor 1 (high affinity)	G-protein coupled neurotensin receptor activity	Molecular function	8381365
ERCC2	2068	excision repair cross-complementation group 2	hair follicle maturation	Biological process	-
WIPI1	55062	WD repeat domain, phosphoinositide interacting 1	cellular protein metabolic process	Biological process	-
NPAS1	4861	neuronal PAS domain protein 1	regulation of transcription from RNA polymerase II promoter	Biological process	-
PINX1	54984	PIN2/TERF1 interacting, telomerase inhibitor 1	spindle	Cellular component	19393617
UGT2B7	7364	UDP glucuronosyltransferase 2 family, polypeptide B7	androgen metabolic process	Biological process	17442341
MGMT	4255	O-6-methylguanine-DNA methyltransferase	damaged DNA binding	Molecular function	-
E2F8	79733	E2F transcription factor 8	transcription corepressor activity	Molecular function	-
ASUN	55726	asunder spermatogenesis regulator	protein localization to nuclear envelope	Biological process	23097494
GRM4	2914	glutamate receptor, metabotropic 4	learning	Biological process	-
TNFRSF1B	7133	tumor necrosis factor receptor superfamily, member 1B	inflammatory response	Biological process	-
ANG	283	angiogenin, ribonuclease, RNase A family, 5	cell migration	Biological process	17125737
IL31RA	133396	interleukin 31 receptor A	negative regulation of apoptotic process	Biological process	11877449
CDK7	1022	cyclin-dependent kinase 7	mitochondrion	Cellular component	-
SMO	6608	smoothened, frizzled class receptor	negative regulation of epithelial cell differentiation	Biological process	-
ACACB	32	acetyl-CoA carboxylase beta	biotin metabolic process	Biological process	-
USP1	7398	ubiquitin specific peptidase 1	DNA damage response, detection of DNA damage	Biological process	-
TYMP	1890	thymidine phosphorylase	cell differentiation	Biological process	-
FMO3	2328	flavin containing monooxygenase 3	flavin adenine dinucleotide binding	Molecular function	-
ZSCAN5C	649137	zinc finger and SCAN domain containing 5C	transcription from RNA polymerase II promoter	Biological process	-
CADPS2	93664	Ca++-dependent secretion activator 2	protein transport	Biological process	-
TLR4	7099	toll-like receptor 4	T-helper 1 type immune response	Biological process	11970998
STIL	6491	SCL/TAL1 interrupting locus	cilium morphogenesis	Biological process	-
HEY2	23493	hes-related family bHLH transcription factor with YRPW motif 2	umbilical cord morphogenesis	Biological process	-
TEX14	56155	testis expressed 14	condensed chromosome kinetochore	Cellular component	-
MNX1	3110	motor neuron and pancreas homeobox 1	regulation of transcription from RNA polymerase II promoter	Biological process	9843207
TNFSF13	8741	tumor necrosis factor (ligand) superfamily, member 13	positive regulation of cell proliferation	Biological process	-
KCNJ11	3767	potassium channel, inwardly rectifying subfamily J, member 11	response to ATP	Biological process	15583126
PDPK1	5170	3-phosphoinositide dependent protein kinase 1	protein autophosphorylation	Biological process	15209375
THRSP	7069	thyroid hormone responsive	regulation of triglyceride biosynthetic process	Biological process	-
STX1A	6804	syntaxin 1A (brain)	protein binding	Molecular function	10321247
IFNB1	3456	interferon, beta 1, fibroblast	cytokine activity	Molecular function	19008854
RDH5	5959	retinol dehydrogenase 5 (11-cis/9-cis)	endoplasmic reticulum lumen	Cellular component	-
TRIM23	373	tripartite motif containing 23	protein binding	Molecular function	16189514
AKAP9	10142	A kinase (PRKA) anchor protein 9	protein complex scaffold	Molecular function	11799244
MC4R	4160	melanocortin 4 receptor	diet induced thermogenesis	Biological process	-
SYT8	90019	synaptotagmin VIII	synaptic vesicle endocytosis	Biological process	-
NFKB2	4791	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	toll-like receptor TLR1:TLR2 signaling pathway	Biological process	-
FOXF1	2294	forkhead box F1	vasculogenesis	Biological process	-
ADORA1	134	adenosine A1 receptor	regulation of sensory perception of pain	Biological process	-
PFKFB1	5207	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	response to glucocorticoid	Biological process	-
MTR	4548	5-methyltetrahydrofolate-homocysteine methyltransferase	water-soluble vitamin metabolic process	Biological process	-
RBM10	8241	RNA binding motif protein 10	mRNA processing	Biological process	-
CDK5R1	8851	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	nucleus	Cellular component	-
ADAMTSL2	9719	ADAMTS-like 2	metalloendopeptidase activity	Molecular function	-
VCL	7414	vinculin	costamere	Cellular component	-
DEDD2	162989	death effector domain containing 2	positive regulation of extrinsic apoptotic signaling pathway	Biological process	11741985
DNAJB11	51726	DnaJ (Hsp40) homolog, subfamily B, member 11	endoplasmic reticulum	Cellular component	16130169
RPL39	6170	ribosomal protein L39	translational termination	Biological process	-
MAPK13	5603	mitogen-activated protein kinase 13	cytosol	Cellular component	-
CDKN2AIP	55602	CDKN2A interacting protein	granular component	Cellular component	12154087
KRT16	3868	keratin 16, type I	intermediate filament	Cellular component	2451124
MED14	9282	mediator complex subunit 14	transcription cofactor activity	Molecular function	12218053
THOC6	79228	THO complex 6	central nervous system development	Biological process	23621916
WNT3A	89780	wingless-type MMTV integration site family, member 3A	protein domain specific binding	Molecular function	-
HLA-DRB3	3125	major histocompatibility complex, class II, DR beta 3	negative regulation of T cell proliferation	Biological process	15795121
MMP11	4320	matrix metallopeptidase 11	basement membrane organization	Biological process	-
MSGN1	343930	mesogenin 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
TTC37	9652	tetratricopeptide repeat domain 37	Ski complex	Cellular component	16024656
FSHB	2488	follicle stimulating hormone, beta polypeptide	female pregnancy	Biological process	8220432
DNAJB5	25822	DnaJ (Hsp40) homolog, subfamily B, member 5	chaperone binding	Molecular function	21231916
TERT	7015	telomerase reverse transcriptase	nucleotidyltransferase activity	Molecular function	19701182
RPL6	6128	ribosomal protein L6	gene expression	Biological process	-
TNRC6B	23112	trinucleotide repeat containing 6B	fibroblast growth factor receptor signaling pathway	Biological process	-
MEF2C	4208	myocyte enhancer factor 2C	negative regulation of transcription from RNA polymerase II promoter	Biological process	18079734
DNAJC4	3338	DnaJ (Hsp40) homolog, subfamily C, member 4	integral component of membrane	Cellular component	-
CHMP4B	128866	charged multivesicular body protein 4B	vacuolar transport	Biological process	-
NLGN4X	57502	neuroligin 4, X-linked	neuron cell-cell adhesion	Biological process	18923512
ASGR1	432	asialoglycoprotein receptor 1	receptor-mediated endocytosis	Biological process	8439566
ACTR3B	57180	ARP3 actin-related protein 3 homolog B (yeast)	cytoplasm	Cellular component	-
PI4KAP2	375133	phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 2	phosphotransferase activity, alcohol group as acceptor	Molecular function	-
HDAC1	3065	histone deacetylase 1	negative regulation of cell cycle	Biological process	-
PARK7	11315	parkinson protein 7	negative regulation of TRAIL-activated apoptotic signaling pathway	Biological process	21785459
CKMT2	1160	creatine kinase, mitochondrial 2 (sarcomeric)	mitochondrion	Cellular component	20833797
MRPS36	92259	mitochondrial ribosomal protein S36	mitochondrial inner membrane	Cellular component	-
ZMYM5	9205	zinc finger, MYM-type 5	protein binding	Molecular function	25416956
CLCN3	1182	chloride channel, voltage-sensitive 3	apical plasma membrane	Cellular component	-
CEP85	64793	centrosomal protein 85kDa	cytoplasm	Cellular component	-
GABRA5	2558	gamma-aminobutyric acid (GABA) A receptor, alpha 5	GABA receptor binding	Molecular function	-
SPTBN4	57731	spectrin, beta, non-erythrocytic 4	clustering of voltage-gated sodium channels	Biological process	-
MYF6	4618	myogenic factor 6 (herculin)	positive regulation of muscle cell differentiation	Biological process	-
NMU	10874	neuromedin U	extracellular region	Cellular component	-
NUP210	23225	nucleoporin 210kDa	glucose transport	Biological process	-
M6PR	4074	mannose-6-phosphate receptor (cation dependent)	integral component of plasma membrane	Cellular component	10799489
ADCY9	115	adenylate cyclase 9	plasma membrane	Cellular component	-
SSB	6741	Sjogren syndrome antigen B (autoantigen La)	poly(A) RNA binding	Molecular function	22658674
CAPN2	824	calpain 2, (m/II) large subunit	extracellular exosome	Cellular component	19056867
CCL5	6352	chemokine (C-C motif) ligand 5	protein self-association	Molecular function	10488085
UNC13A	23025	unc-13 homolog A (C. elegans)	synaptic vesicle maturation	Biological process	-
MED27	9442	mediator complex subunit 27	gene expression	Biological process	-
ITGB1BP1	9270	integrin beta 1 binding protein 1	blood vessel endothelial cell proliferation involved in sprouting angiogenesis	Biological process	20616313
ZBTB16	7704	zinc finger and BTB domain containing 16	protein domain specific binding	Molecular function	-
LPIN2	9663	lipin 2	cellular lipid metabolic process	Biological process	-
PEX5	5830	peroxisomal biogenesis factor 5	protein import into peroxisome membrane	Biological process	14709540
SALL3	27164	spalt-like transcription factor 3	forelimb morphogenesis	Biological process	-
RAB20	55647	RAB20, member RAS oncogene family	Rab protein signal transduction	Biological process	-
RELA	5970	v-rel avian reticuloendotheliosis viral oncogene homolog A	toll-like receptor 2 signaling pathway	Biological process	-
DYNC1I2	1781	dynein, cytoplasmic 1, intermediate chain 2	centrosome	Cellular component	21399614
BCL3	602	B-cell CLL/lymphoma 3	response to virus	Biological process	16306601
MYLIP	29116	myosin regulatory light chain interacting protein	ubiquitin-protein transferase activity	Molecular function	14550572
AKAP10	11216	A kinase (PRKA) anchor protein 10	blood coagulation	Biological process	-
PANX1	24145	pannexin 1	positive regulation of interleukin-1 beta secretion	Biological process	17036048
CDC25B	994	cell division cycle 25B	positive regulation of mitotic cell cycle	Biological process	17332740
IGKV3-20	28912	immunoglobulin kappa variable 3-20	monomeric IgA immunoglobulin complex	Cellular component	23250751
AHSG	197	alpha-2-HS-glycoprotein	cysteine-type endopeptidase inhibitor activity	Molecular function	-
ZNF888	388559	zinc finger protein 888	DNA binding	Molecular function	-
YBX1	4904	Y box binding protein 1	nucleoplasm	Cellular component	-
RPS27A	6233	ribosomal protein S27a	viral transcription	Biological process	-
RPP30	10556	ribonuclease P/MRP 30kDa subunit	tRNA processing	Biological process	-
HRASLS2	54979	HRAS-like suppressor 2	lipid catabolic process	Biological process	-
OGFOD2	79676	2-oxoglutarate and iron-dependent oxygenase domain containing 2	oxidation-reduction process	Biological process	-
CCT5	22948	chaperonin containing TCP1, subunit 5 (epsilon)	microtubule	Cellular component	21525035
BYSL	705	bystin-like	cell adhesion	Biological process	9560222
PGLYRP1	8993	peptidoglycan recognition protein 1	peptidoglycan receptor activity	Molecular function	11461926
TIRAP	114609	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	defense response to Gram-positive bacterium	Biological process	-
LYN	4067	LYN proto-oncogene, Src family tyrosine kinase	regulation of cytokine secretion	Biological process	-
PTPN22	26191	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	phosphoanandamide dephosphorylation	Biological process	-
TAP2	6891	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	peptide transporter activity	Molecular function	7673167
EPHA3	2042	EPH receptor A3	ATP binding	Molecular function	-
ARC	23237	activity-regulated cytoskeleton-associated protein	acrosomal vesicle	Cellular component	-
HEXB	3074	hexosaminidase B (beta polypeptide)	hyaluronan metabolic process	Biological process	-
SP4	6671	Sp4 transcription factor	transcription coactivator activity	Molecular function	-
HAP1	9001	huntingtin-associated protein 1	retrograde axon cargo transport	Biological process	-
SMAD3	4088	SMAD family member 3	positive regulation of extracellular matrix assembly	Biological process	21307346
C4BPB	725	complement component 4 binding protein, beta	protein binding	Molecular function	14607961
MSR1	4481	macrophage scavenger receptor 1	cholesterol transport	Biological process	12376530
KIRREL	55243	kin of IRRE like (Drosophila)	cell projection membrane	Cellular component	-
CYP2R1	120227	cytochrome P450, family 2, subfamily R, polypeptide 1	steroid metabolic process	Biological process	-
DZIP3	9666	DAZ interacting zinc finger protein 3	phosphatase binding	Molecular function	19389623
MAP2K3	5606	mitogen-activated protein kinase kinase 3	regulation of apoptotic process	Biological process	-
DPP4	1803	dipeptidyl-peptidase 4	serine-type endopeptidase activity	Molecular function	-
TEX14	56155	testis expressed 14	negative regulation of protein binding	Biological process	-
TH	7054	tyrosine hydroxylase	response to nutrient levels	Biological process	-
PLD6	201164	phospholipase D family, member 6	metal ion binding	Molecular function	-
NKRF	55922	NFKB repressing factor	transcription, DNA-templated	Biological process	-
ZDHHC17	23390	zinc finger, DHHC-type containing 17	Golgi apparatus	Cellular component	-
SRCIN1	80725	SRC kinase signaling inhibitor 1	postsynaptic membrane	Cellular component	-
HSPA1A	3303	heat shock 70kDa protein 1A	negative regulation of cell growth	Biological process	9553041
JMY	133746	junction mediating and regulatory protein, p53 cofactor	cell leading edge	Cellular component	19287377
PDCD6	10016	programmed cell death 6	protein anchor	Molecular function	16957052
GK2	2712	glycerol kinase 2	glycerol-3-phosphate biosynthetic process	Biological process	-
SNTB2	6645	syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)	protein binding	Molecular function	12763866
TGFB1I1	7041	transforming growth factor beta 1 induced transcript 1	epithelial cell differentiation	Biological process	-
ELL3	80237	elongation factor RNA polymerase II-like 3	positive regulation of transcription from RNA polymerase II promoter	Biological process	10882741
CFTR	1080	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	response to cytokine	Biological process	-
RGS14	10636	regulator of G-protein signaling 14	dendrite	Cellular component	-
TLX3	30012	T-cell leukemia homeobox 3	negative regulation of neuron differentiation	Biological process	-
SERPINB9	5272	serpin peptidase inhibitor, clade B (ovalbumin), member 9	extracellular exosome	Cellular component	20458337
PTK7	5754	protein tyrosine kinase 7 (inactive)	wound healing	Biological process	-
MED1	5469	mediator complex subunit 1	lactation	Biological process	-
PDGFA	5154	platelet-derived growth factor alpha polypeptide	response to wounding	Biological process	2538439
XRN2	22803	5'-3' exoribonuclease 2	DNA catabolic process, exonucleolytic	Biological process	15565158
GCHFR	2644	GTP cyclohydrolase I feedback regulator	protein binding	Molecular function	16696853
OGT	8473	O-linked N-acetylglucosamine (GlcNAc) transferase	cytosol	Cellular component	21285374
TCAIM	285343	T cell activation inhibitor, mitochondrial	mitochondrion	Cellular component	-
HPS1	3257	Hermansky-Pudlak syndrome 1	cytoplasm	Cellular component	10625677
NMBR	4829	neuromedin B receptor	cytoplasm	Cellular component	-
SMC5	23137	structural maintenance of chromosomes 5	PML body	Cellular component	17589526
NIPAL2	79815	NIPA-like domain containing 2	magnesium ion transport	Biological process	-
CCDC62	84660	coiled-coil domain containing 62	cytoplasm	Cellular component	-
LILRA2	11027	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2	signal transduction	Biological process	9548455
DLK1	8788	delta-like 1 homolog (Drosophila)	multicellular organismal development	Biological process	8500166
ITIH5	80760	inter-alpha-trypsin inhibitor heavy chain family, member 5	negative regulation of endopeptidase activity	Biological process	-
LEO1	123169	Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	positive regulation of transcription elongation from RNA polymerase II promoter	Biological process	20178742
BMP4	652	bone morphogenetic protein 4	steroid hormone mediated signaling pathway	Biological process	17244894
HLA-DRB5	3127	major histocompatibility complex, class II, DR beta 5	T cell receptor signaling pathway	Biological process	-
PAK4	10298	p21 protein (Cdc42/Rac)-activated kinase 4	ATP binding	Molecular function	-
NCBP1	4686	nuclear cap binding protein subunit 1, 80kDa	RNA binding	Molecular function	8069914
OR8J1	219477	olfactory receptor, family 8, subfamily J, member 1	olfactory receptor activity	Molecular function	-
ICAM4	3386	intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)	cell adhesion	Biological process	-
IFNE	338376	interferon, epsilon	type I interferon receptor binding	Molecular function	-
IL10	3586	interleukin 10	cytokine activity	Molecular function	10443688
PC	5091	pyruvate carboxylase	pyruvate carboxylase activity	Molecular function	-
CLDN22	53842	claudin 22	bicellular tight junction	Cellular component	-
NPAS1	4861	neuronal PAS domain protein 1	sequence-specific DNA binding transcription factor activity	Molecular function	9012850
HOXD12	3238	homeobox D12	protein binding	Molecular function	25416956
TGFBR3	7049	transforming growth factor, beta receptor III	negative regulation of transforming growth factor beta receptor signaling pathway	Biological process	-
DDO	8528	D-aspartate oxidase	protein binding	Molecular function	9820813
HSPD1	3329	heat shock 60kDa protein 1 (chaperonin)	single-stranded DNA binding	Molecular function	-
POU4F3	5459	POU class 4 homeobox 3	neuron apoptotic process	Biological process	-
PIM3	415116	Pim-3 proto-oncogene, serine/threonine kinase	protein serine/threonine kinase activity	Molecular function	18593906
GJA5	2702	gap junction protein, alpha 5, 40kDa	regulation of cardiac muscle contraction	Biological process	16790700
PSME3	10197	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)	regulation of cellular amino acid metabolic process	Biological process	-
FOXC2	2303	forkhead box C2	metanephros development	Biological process	-
SLC34A2	10568	solute carrier family 34 (type II sodium/phosphate cotransporter), member 2	brush border membrane	Cellular component	-
EXOSC5	56915	exosome component 5	cytoplasm	Cellular component	11110791
PDE4D	5144	phosphodiesterase 4D, cAMP-specific	metal ion binding	Molecular function	-
GRAMD1B	57476	GRAM domain containing 1B	membrane	Cellular component	19946888
CCL28	56477	chemokine (C-C motif) ligand 28	extracellular exosome	Cellular component	19199708
FAM26D	221301	family with sequence similarity 26, member D	cation transmembrane transport	Biological process	-
TBCK	93627	TBC1 domain containing kinase	protein phosphorylation	Biological process	12471243
AGT	183	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	regulation of blood pressure	Biological process	17416596
SRCIN1	80725	SRC kinase signaling inhibitor 1	negative regulation of protein tyrosine kinase activity	Biological process	17525734
RPL23	9349	ribosomal protein L23	viral transcription	Biological process	-
DAG1	1605	dystroglycan 1 (dystrophin-associated glycoprotein 1)	microtubule anchoring	Biological process	18341635
EIF2AK2	5610	eukaryotic translation initiation factor 2-alpha kinase 2	negative regulation of osteoblast proliferation	Biological process	16216244
NPFFR1	64106	neuropeptide FF receptor 1	cellular response to hormone stimulus	Biological process	-
FKTN	2218	fukutin	muscle organ development	Biological process	9690476
STK39	27347	serine threonine kinase 39	response to stress	Biological process	10980603
KCNQ2	3785	potassium channel, voltage gated KQT-like subfamily Q, member 2	plasma membrane	Cellular component	-
KRTAP13-4	284827	keratin associated protein 13-4	intermediate filament	Cellular component	-
ATP5D	513	ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit	response to copper ion	Biological process	12539966
CACNG4	27092	calcium channel, voltage-dependent, gamma subunit 4	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity	Biological process	21172611
GREM1	26585	gremlin 1, DAN family BMP antagonist	negative regulation of branching involved in ureteric bud morphogenesis	Biological process	-
GDF9	2661	growth differentiation factor 9	positive regulation of cell proliferation	Biological process	19366876
STAT5B	6777	signal transducer and activator of transcription 5B	positive regulation of cellular component movement	Biological process	-
IQGAP2	10788	IQ motif containing GTPase activating protein 2	microvillus	Cellular component	-
ROCK1	6093	Rho-associated, coiled-coil containing protein kinase 1	ephrin receptor signaling pathway	Biological process	-
CRCP	27297	CGRP receptor component	acrosomal vesicle	Cellular component	-
STK11	6794	serine/threonine kinase 11	protein kinase activator activity	Molecular function	19892943
PSMD13	5719	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	viral process	Biological process	-
AHR	196	aryl hydrocarbon receptor	cytoplasm	Cellular component	-
ATF2	1386	activating transcription factor 2	regulation of transcription from RNA polymerase II promoter	Biological process	19861239
SEMA3F	6405	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	sympathetic neuron projection extension	Biological process	-
ATF7	11016	activating transcription factor 7	sequence-specific DNA binding	Molecular function	-
CYP24A1	1591	cytochrome P450, family 24, subfamily A, polypeptide 1	oxidation-reduction process	Biological process	8506296
TGIF1	7050	TGFB-induced factor homeobox 1	dorsal/ventral pattern formation	Biological process	-
BCO1	53630	beta-carotene oxygenase 1	retinol metabolic process	Biological process	-
USP33	23032	ubiquitin specific peptidase 33	perinuclear region of cytoplasm	Cellular component	24056301
COA4	51287	cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae)	mitochondrion	Cellular component	-
FECH	2235	ferrochelatase	response to platinum ion	Biological process	-
PDE6D	5147	phosphodiesterase 6D, cGMP-specific, rod, delta	primary cilium	Cellular component	-
DUSP21	63904	dual specificity phosphatase 21	cytoplasm	Cellular component	12408986
SEC24B	10427	SEC24 family member B	vesicle-mediated transport	Biological process	10075675
FRZB	2487	frizzled-related protein	Wnt-protein binding	Molecular function	-
BARX1	56033	BARX homeobox 1	anterior/posterior pattern specification	Biological process	-
SHMT1	6470	serine hydroxymethyltransferase 1 (soluble)	protein homodimerization activity	Molecular function	9753690
PLCG1	5335	phospholipase C, gamma 1	cytoplasm	Cellular component	15702972
ACHE	43	acetylcholinesterase (Yt blood group)	positive regulation of protein secretion	Biological process	11283752
FILIP1L	11259	filamin A interacting protein 1-like	cytoplasm	Cellular component	-
FGFR2	2263	fibroblast growth factor receptor 2	innate immune response	Biological process	-
HYAL2	8692	hyaluronoglucosaminidase 2	cytoplasm	Cellular component	17170110
CRHBP	1393	corticotropin releasing hormone binding protein	signal transduction	Biological process	7477348
SGCD	6444	sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)	muscle cell development	Biological process	-
SLC11A2	4891	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2	ferrous iron transmembrane transport	Biological process	25491917
ISCA1	81689	iron-sulfur cluster assembly 1	metal ion binding	Molecular function	-
PKNOX2	63876	PBX/knotted 1 homeobox 2	regulation of transcription from RNA polymerase II promoter	Biological process	-
SPEG	10290	SPEG complex locus	negative regulation of cell proliferation	Biological process	8663449
STX4	6810	syntaxin 4	positive regulation of catalytic activity	Biological process	20956541
MAF	4094	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
NFYB	4801	nuclear transcription factor Y, beta	positive regulation of transcription, DNA-templated	Biological process	-
NAA15	80155	N(alpha)-acetyltransferase 15, NatA auxiliary subunit	poly(A) RNA binding	Molecular function	22658674
OR5H14	403273	olfactory receptor, family 5, subfamily H, member 14	sensory perception of smell	Biological process	-
SIX4	51804	SIX homeobox 4	regulation of epithelial cell proliferation	Biological process	-
CANX	821	calnexin	ionotropic glutamate receptor binding	Molecular function	-
CADPS	8618	Ca++-dependent secretion activator	metal ion binding	Molecular function	-
NOD1	10392	nucleotide-binding oligomerization domain containing 1	toll-like receptor 2 signaling pathway	Biological process	-
STAT5B	6777	signal transducer and activator of transcription 5B	response to interleukin-2	Biological process	-
PDGFRB	5159	platelet-derived growth factor receptor, beta polypeptide	positive regulation of phosphatidylinositol 3-kinase activity	Biological process	1314164
PAN3	255967	PAN3 poly(A) specific ribonuclease subunit	nuclear-transcribed mRNA poly(A) tail shortening	Biological process	-
SLC30A1	7779	solute carrier family 30 (zinc transporter), member 1	cellular zinc ion homeostasis	Biological process	-
TXNIP	10628	thioredoxin interacting protein	protein binding	Molecular function	14632196
CATSPER4	378807	cation channel, sperm associated 4	calcium activated cation channel activity	Molecular function	-
TEAD2	8463	TEA domain family member 2	lateral mesoderm development	Biological process	-
PARK7	11315	parkinson protein 7	proteolysis	Biological process	-
TOMM70A	9868	translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)	protein binding	Molecular function	12526792
HSPA1A	3303	heat shock 70kDa protein 1A	cellular heat acclimation	Biological process	21231916
TMEM128	85013	transmembrane protein 128	molecular_function	Molecular function	-
GATA1	2623	GATA binding protein 1 (globin transcription factor 1)	RNA polymerase II transcription factor binding	Molecular function	11675338
ARID1A	8289	AT rich interactive domain 1A (SWI-like)	androgen receptor signaling pathway	Biological process	12200431
HAUS2	55142	HAUS augmin-like complex, subunit 2	organelle organization	Biological process	-
HEXIM1	10614	hexamethylene bis-acetamide inducible 1	negative regulation of transcription, DNA-templated	Biological process	14580347
GPR37L1	9283	G protein-coupled receptor 37 like 1	plasma membrane	Cellular component	-
ARL6	84100	ADP-ribosylation factor-like 6	organelle organization	Biological process	-
IGF1	3479	insulin-like growth factor 1 (somatomedin C)	cell proliferation	Biological process	1847964
CD24	100133941	CD24 molecule	protein tyrosine kinase activator activity	Molecular function	11313396
CCNY	219771	cyclin Y	nucleus	Cellular component	-
ASTN2	23245	astrotactin 2	negative regulation of protein localization to cell surface	Biological process	-
MITD1	129531	MIT, microtubule interacting and transport, domain containing 1	protein domain specific binding	Molecular function	23015756
ORM2	5005	orosomucoid 2	regulation of immune system process	Biological process	-
CDK4	1019	cyclin-dependent kinase 4	positive regulation of apoptotic process	Biological process	-
PROK1	84432	prokineticin 1	growth factor activity	Molecular function	-
EPN1	29924	epsin 1	plasma membrane	Cellular component	-
MAGED1	9500	melanoma antigen family D1	positive regulation of branching involved in ureteric bud morphogenesis	Biological process	-
PPP1R15B	84919	protein phosphatase 1, regulatory subunit 15B	protein serine/threonine phosphatase activity	Molecular function	-
BAX	581	BCL2-associated X protein	negative regulation of neuron apoptotic process	Biological process	-
CLDN22	53842	claudin 22	identical protein binding	Molecular function	-
ERBB2	2064	erb-b2 receptor tyrosine kinase 2	positive regulation of cell adhesion	Biological process	7556068
FLT4	2324	fms-related tyrosine kinase 4	plasma membrane	Cellular component	-
BHMT2	23743	betaine--homocysteine S-methyltransferase 2	S-adenosylmethionine metabolic process	Biological process	18230605
PYY	5697	peptide YY	feeding behavior	Biological process	10698177
CHRNA1	1134	cholinergic receptor, nicotinic, alpha 1 (muscle)	signal transduction	Biological process	7619526
SREBF1	6720	sterol regulatory element binding transcription factor 1	cytosol	Cellular component	-
CATSPER3	347732	cation channel, sperm associated 3	calcium ion transmembrane transport	Biological process	-
ERCC4	2072	excision repair cross-complementation group 4	negative regulation of telomere maintenance	Biological process	17055345
SLC35F3	148641	solute carrier family 35, member F3	thiamine transport	Biological process	24509276
GNAI2	2771	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	blood coagulation	Biological process	-
NLRP1	22861	NLR family, pyrin domain containing 1	apoptotic process	Biological process	11076957
KIAA1715	80856	KIAA1715	embryonic forelimb morphogenesis	Biological process	-
PAK7	57144	p21 protein (Cdc42/Rac)-activated kinase 7	negative regulation of extrinsic apoptotic signaling pathway	Biological process	-
NOS2	4843	nitric oxide synthase 2, inducible	positive regulation of guanylate cyclase activity	Biological process	-
ACAT1	38	acetyl-CoA acetyltransferase 1	brain development	Biological process	-
POLR2L	5441	polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa	transcription elongation from RNA polymerase I promoter	Biological process	-
ABL2	27	ABL proto-oncogene 2, non-receptor tyrosine kinase	protein tyrosine kinase activity	Molecular function	15886098
WFS1	7466	Wolfram syndrome 1 (wolframin)	endoplasmic reticulum membrane	Cellular component	-
IL1RAP	3556	interleukin 1 receptor accessory protein	interleukin-1 receptor activity	Molecular function	-
USP28	57646	ubiquitin specific peptidase 28	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological process	-
IKBKG	8517	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	toll-like receptor 5 signaling pathway	Biological process	-
MYOC	4653	myocilin, trabecular meshwork inducible glucocorticoid response	non-canonical Wnt signaling pathway via JNK cascade	Biological process	19188438
C1QTNF1	114897	C1q and tumor necrosis factor related protein 1	negative regulation of platelet aggregation	Biological process	16195328
ERCC1	2067	excision repair cross-complementation group 1	negative regulation of telomere maintenance	Biological process	17055345
SLC1A2	6506	solute carrier family 1 (glial high affinity glutamate transporter), member 2	telencephalon development	Biological process	-
NEK2	4751	NIMA-related kinase 2	regulation of mitotic centrosome separation	Biological process	16280549
SON	6651	SON DNA binding protein	cytokinesis	Biological process	21504830
NOTCH1	4851	notch 1	inflammatory response to antigenic stimulus	Biological process	-
ZADH2	284273	zinc binding alcohol dehydrogenase domain containing 2	oxidation-reduction process	Biological process	-
EGR2	1959	early growth response 2	cellular response to cAMP	Biological process	-
ITGAV	3685	integrin, alpha V	blood coagulation	Biological process	-
PARP1	142	poly (ADP-ribose) polymerase 1	post-translational protein modification	Biological process	-
PLCH2	9651	phospholipase C, eta 2	intracellular signal transduction	Biological process	-
BCL2L1	598	BCL2-like 1	cellular process regulating host cell cycle in response to virus	Biological process	-
SNCG	6623	synuclein, gamma (breast cancer-specific protein 1)	microtubule organizing center	Cellular component	-
PKP2	5318	plakophilin 2	regulation of heart rate by cardiac conduction	Biological process	17980246
RLF	6018	rearranged L-myc fusion	zinc ion binding	Molecular function	8545128
WAC	51322	WW domain containing adaptor with coiled-coil	nucleoplasm	Cellular component	-
NUPL1	9818	nucleoporin like 1	nucleocytoplasmic transporter activity	Molecular function	-
PKP2	5318	plakophilin 2	protein binding	Molecular function	10852826
HSD17B8	7923	hydroxysteroid (17-beta) dehydrogenase 8	estrogen biosynthetic process	Biological process	-
LILRB2	10288	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	negative regulation of calcium ion transport	Biological process	9842885
YARS2	51067	tyrosyl-tRNA synthetase 2, mitochondrial	ATP binding	Molecular function	15779907
GALNT2	2590	polypeptide N-acetylgalactosaminyltransferase 2	carbohydrate binding	Molecular function	-
P2RY12	64805	purinergic receptor P2Y, G-protein coupled, 12	mitochondrion	Cellular component	-
EIF2B5	8893	eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa	astrocyte development	Biological process	15723074
PKN1	5585	protein kinase N1	regulation of transcription from RNA polymerase II promoter	Biological process	18066052
CNDP1	84735	carnosine dipeptidase 1 (metallopeptidase M20 family)	dipeptidase activity	Molecular function	-
CPTP	80772	ceramide-1-phosphate transfer protein	glycolipid binding	Molecular function	-
BTG3	10950	BTG family, member 3	negative regulation of cell proliferation	Biological process	9632145
ADAM17	6868	ADAM metallopeptidase domain 17	tumor necrosis factor-mediated signaling pathway	Biological process	-
TACC1	6867	transforming, acidic coiled-coil containing protein 1	cell proliferation	Biological process	-
CABIN1	23523	calcineurin binding protein 1	protein phosphatase inhibitor activity	Molecular function	9655484
MRPL17	63875	mitochondrial ribosomal protein L17	structural constituent of ribosome	Molecular function	-
ATG4B	23192	autophagy related 4B, cysteine peptidase	protein targeting to membrane	Biological process	-
PCDHGA12	26025	protocadherin gamma subfamily A, 12	plasma membrane	Cellular component	-
ERVK-11	100862688	endogenous retrovirus group K, member 11	RNA phosphodiester bond hydrolysis, endonucleolytic	Biological process	-
RAMP3	10268	receptor (G protein-coupled) activity modifying protein 3	positive regulation of receptor recycling	Biological process	15613468
KIAA0196	9897	KIAA0196	protein binding	Molecular function	23331060
PRPSAP2	5636	phosphoribosyl pyrophosphate synthetase-associated protein 2	nucleobase-containing compound metabolic process	Biological process	9545573
HSPH1	10808	heat shock 105kDa/110kDa protein 1	response to unfolded protein	Biological process	9931472
NKIRAS1	28512	NFKB inhibitor interacting Ras-like 1	membrane	Cellular component	-
HMOX1	3162	heme oxygenase 1	intracellular signal transduction	Biological process	17652371
GTF2IRD1	9569	GTF2I repeat domain containing 1	nucleoplasm	Cellular component	-
ZFX	7543	zinc finger protein, X-linked	transcription coactivator activity	Molecular function	2105457
IVNS1ABP	10625	influenza virus NS1A binding protein	spliceosomal complex	Cellular component	9696811
MDK	4192	midkine (neurite growth-promoting factor 2)	growth factor activity	Molecular function	1639750
DEFA3	1668	defensin, alpha 3, neutrophil-specific	defense response to virus	Biological process	-
GGH	8836	gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)	nucleus	Cellular component	21630459
SLC24A2	25769	solute carrier family 24 (sodium/potassium/calcium exchanger), member 2	manganese ion binding	Molecular function	-
NR1I3	9970	nuclear receptor subfamily 1, group I, member 3	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	11114890
NPY2R	4887	neuropeptide Y receptor Y2	negative regulation of secretion	Biological process	-
THRAP3	9967	thyroid hormone receptor associated protein 3	intracellular steroid hormone receptor signaling pathway	Biological process	11867769
VLDLR	7436	very low density lipoprotein receptor	very-low-density lipoprotein particle binding	Molecular function	10571240
CLIC2	1193	chloride intracellular channel 2	negative regulation of ryanodine-sensitive calcium-release channel activity	Biological process	15147738
TRPM2	7226	transient receptor potential cation channel, subfamily M, member 2	manganese ion transmembrane transporter activity	Molecular function	-
AQP1	358	aquaporin 1 (Colton blood group)	cellular response to hypoxia	Biological process	18275976
RALA	5898	v-ral simian leukemia viral oncogene homolog A (ras related)	cell surface	Cellular component	19306925
SOX8	30812	SRY (sex determining region Y)-box 8	osteoblast differentiation	Biological process	-
SH3RF1	57630	SH3 domain containing ring finger 1	zinc ion binding	Molecular function	-
AHSA1	10598	AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)	positive regulation of ATPase activity	Biological process	-
PDGFB	5155	platelet-derived growth factor beta polypeptide	blood vessel morphogenesis	Biological process	-
HLA-C	3107	major histocompatibility complex, class I, C	integral component of plasma membrane	Cellular component	1384166
AGFG1	3267	ArfGAP with FG repeats 1	RNA binding	Molecular function	7634337
PRPF8	10594	pre-mRNA processing factor 8	U5 snRNP	Cellular component	9774689
CEBPZ	10153	CCAAT/enhancer binding protein (C/EBP), zeta	nucleus	Cellular component	-
ATP2A2	488	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	endoplasmic reticulum	Cellular component	16081076
TMEM135	65084	transmembrane protein 135	peroxisome	Cellular component	-
PAX6	5080	paired box 6	cornea development in camera-type eye	Biological process	7550230
ADRA1D	146	adrenoceptor alpha 1D	multicellular organismal development	Biological process	10820200
SLC25A3	5250	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3	symporter activity	Molecular function	-
KNG1	3827	kininogen 1	extracellular region	Cellular component	-
ALDOA	226	aldolase A, fructose-bisphosphate	actin cytoskeleton	Cellular component	9244396
ALDH18A1	5832	aldehyde dehydrogenase 18 family, member A1	glutamate metabolic process	Biological process	11092761
CREBL2	1389	cAMP responsive element binding protein-like 2	sequence-specific DNA binding	Molecular function	-
COMT	1312	catechol-O-methyltransferase	dopamine catabolic process	Biological process	-
RHOU	58480	ras homolog family member U	focal adhesion	Cellular component	-
TRNP1	388610	TMF1-regulated nuclear protein 1	DNA binding	Molecular function	-
HSPA1A	3303	heat shock 70kDa protein 1A	ubiquitin protein ligase binding	Molecular function	12150907
PEX19	5824	peroxisomal biogenesis factor 19	peroxisome membrane class-1 targeting sequence binding	Molecular function	14709540
ADAM2	2515	ADAM metallopeptidase domain 2	zinc ion binding	Molecular function	-
XYLT2	64132	xylosyltransferase II	heparin biosynthetic process	Biological process	-
TP53	7157	tumor protein p53	protein heterodimerization activity	Molecular function	10837489
TNFSF13B	10673	tumor necrosis factor (ligand) superfamily, member 13b	signal transduction	Biological process	10908663
NARS	4677	asparaginyl-tRNA synthetase	cytosol	Cellular component	-
RBKS	64080	ribokinase	ribokinase activity	Molecular function	-
H6PD	9563	hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)	NADP binding	Molecular function	-
SIRT1	23411	sirtuin 1	cellular response to starvation	Biological process	-
UBC	7316	ubiquitin C	Notch signaling pathway	Biological process	-
RBM14	10432	RNA binding motif protein 14	transcription from RNA polymerase II promoter	Biological process	11443112
ZNF541	84215	zinc finger protein 541	transcription, DNA-templated	Biological process	-
NMRK2	27231	nicotinamide riboside kinase 2	metal ion binding	Molecular function	-
KDM7A	80853	lysine (K)-specific demethylase 7A	positive regulation of transcription, DNA-templated	Biological process	-
HELT	391723	helt bHLH transcription factor	suckling behavior	Biological process	-
RAB3A	5864	RAB3A, member RAS oncogene family	vesicle docking involved in exocytosis	Biological process	-
IGLC2	3538	immunoglobulin lambda constant 2 (Kern-Oz- marker)	extracellular region	Cellular component	-
IAPP	3375	islet amyloid polypeptide	signal transduction	Biological process	10342886
MKRN2	23609	makorin ring finger protein 2	poly(A) RNA binding	Molecular function	22681889
PHGDH	26227	phosphoglycerate dehydrogenase	regulation of gene expression	Biological process	-
MUS81	80198	MUS81 structure-specific endonuclease subunit	nucleolus	Cellular component	-
EGFR	1956	epidermal growth factor receptor	positive regulation of protein kinase B signaling	Biological process	17655843
SCN1B	6324	sodium channel, voltage gated, type I beta subunit	sodium ion transmembrane transport	Biological process	14622265
CD28	940	CD28 molecule	fibroblast growth factor receptor signaling pathway	Biological process	-
PARK2	5071	parkin RBR E3 ubiquitin protein ligase	negative regulation of spontaneous neurotransmitter secretion	Biological process	22314364
LRRC4C	57689	leucine rich repeat containing 4C	cell junction	Cellular component	-
MYLK4	340156	myosin light chain kinase family, member 4	protein serine/threonine kinase activity	Molecular function	-
PITX2	5308	paired-like homeodomain 2	response to hormone	Biological process	-
OR13A1	79290	olfactory receptor, family 13, subfamily A, member 1	sensory perception of smell	Biological process	-
ASMT	438	acetylserotonin O-methyltransferase	cytosol	Cellular component	-
LIN7C	55327	lin-7 homolog C (C. elegans)	synapse	Cellular component	-
FBXW7	55294	F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase	ubiquitin-protein transferase activator activity	Molecular function	12628165
POLH	5429	polymerase (DNA directed), eta	DNA replication	Biological process	-
NPAT	4863	nuclear protein, ataxia-telangiectasia locus	negative regulation of nucleic acid-templated transcription	Biological process	17163457
SARM1	23098	sterile alpha and TIR motif containing 1	microtubule	Cellular component	-
SLC38A7	55238	solute carrier family 38, member 7	L-glutamate transport	Biological process	-
GRB10	2887	growth factor receptor-bound protein 10	negative regulation of glycogen biosynthetic process	Biological process	-
RREB1	6239	ras responsive element binding protein 1	positive regulation of epithelial cell migration	Biological process	18394891
SLC25A33	84275	solute carrier family 25 (pyrimidine nucleotide carrier), member 33	pyrimidine nucleotide transmembrane transporter activity	Molecular function	17596519
LGR6	59352	leucine-rich repeat containing G protein-coupled receptor 6	G-protein coupled receptor activity	Molecular function	-
SSX5	6758	synovial sarcoma, X breakpoint 5	nucleus	Cellular component	-
GABRB3	2562	gamma-aminobutyric acid (GABA) A receptor, beta 3	sensory perception of sound	Biological process	-
PGAP1	80055	post-GPI attachment to proteins 1	integral component of membrane	Cellular component	-
GNB3	2784	guanine nucleotide binding protein (G protein), beta polypeptide 3	energy reserve metabolic process	Biological process	-
RORA	6095	RAR-related orphan receptor A	positive regulation of transcription, DNA-templated	Biological process	7926749
OR52E4	390081	olfactory receptor, family 52, subfamily E, member 4	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
KLF8	11279	Kruppel-like factor 8	DNA binding	Molecular function	-
EMX1	2016	empty spiracles homeobox 1	response to drug	Biological process	-
EXOSC2	23404	exosome component 2	rRNA processing	Biological process	8600032
CENPE	1062	centromere protein E, 312kDa	mitotic chromosome movement towards spindle pole	Biological process	1406971
PRMT1	3276	protein arginine methyltransferase 1	histone methyltransferase activity (H4-R3 specific)	Molecular function	11448779
PINK1	65018	PTEN induced putative kinase 1	positive regulation of protein targeting to mitochondrion	Biological process	24270810
GALNT7	51809	polypeptide N-acetylgalactosaminyltransferase 7	integral component of membrane	Cellular component	-
PRMT8	56341	protein arginine methyltransferase 8	histone arginine methylation	Biological process	16051612
TRIM71	131405	tripartite motif containing 71, E3 ubiquitin protein ligase	neural tube development	Biological process	-
LACRT	90070	lacritin	collagen binding	Molecular function	11419941
POU3F2	5454	POU class 3 homeobox 2	positive regulation of multicellular organism growth	Biological process	-
COL5A2	1290	collagen, type V, alpha 2	extracellular matrix	Cellular component	17666000
TRNAU1AP	54952	tRNA selenocysteine 1 associated protein 1	nucleotide binding	Molecular function	-
BRCA2	675	breast cancer 2, early onset	chromosome organization	Biological process	-
COX14	84987	COX14 cytochrome c oxidase assembly factor	mitochondrion	Cellular component	-
FAM120B	84498	family with sequence similarity 120B	nucleus	Cellular component	-
ATIC	471	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	brainstem development	Biological process	-
WNT1	7471	wingless-type MMTV integration site family, member 1	positive regulation of lamellipodium assembly	Biological process	19756656
SYT2	127833	synaptotagmin II	protein binding	Molecular function	19234194
ANAPC4	29945	anaphase promoting complex subunit 4	mitotic spindle assembly checkpoint	Biological process	-
CASK	8573	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	positive regulation of calcium ion import	Biological process	-
TOB1	10140	transducer of ERBB2, 1	negative regulation of nucleic acid-templated transcription	Biological process	-
GLI2	2736	GLI family zinc finger 2	chondrocyte differentiation	Biological process	-
GMNC	647309	geminin coiled-coil domain containing	cell cycle	Biological process	-
ZBTB18	10472	zinc finger and BTB domain containing 18	negative regulation of transcription, DNA-templated	Biological process	-
EIF2B3	8891	eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa	cellular protein metabolic process	Biological process	-
PSAPL1	768239	prosaposin-like 1 (gene/pseudogene)	cytoplasm	Cellular component	-
SH3BP4	23677	SH3-domain binding protein 4	identical protein binding	Molecular function	16325581
KMO	8564	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	mitochondrial outer membrane	Cellular component	10672018
UST	10090	uronyl-2-sulfotransferase	dermatan sulfate biosynthetic process	Biological process	-
ADORA1	134	adenosine A1 receptor	integral component of plasma membrane	Cellular component	1530647
SLC22A1	6580	solute carrier family 22 (organic cation transporter), member 1	quaternary ammonium group transport	Biological process	-
EREG	2069	epiregulin	activation of MAPK activity	Biological process	-
PTCRA	171558	pre T-cell antigen receptor alpha	integral component of membrane	Cellular component	-
MAPKAP1	79109	mitogen-activated protein kinase associated protein 1	negative regulation of Ras protein signal transduction	Biological process	17303383
PIGG	54872	phosphatidylinositol glycan anchor biosynthesis, class G	endoplasmic reticulum	Cellular component	15632136
PDE5A	8654	phosphodiesterase 5A, cGMP-specific	relaxation of cardiac muscle	Biological process	-
STAU1	6780	staufen double-stranded RNA binding protein 1	cytoplasmic ribonucleoprotein granule	Cellular component	15121898
POLR2K	5440	polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa	regulation of gene expression, epigenetic	Biological process	-
PKDREJ	10343	polycystin (PKD) family receptor for egg jelly	plasma membrane	Cellular component	-
FOXJ1	2302	forkhead box J1	lung epithelium development	Biological process	9096351
CALM3	808	calmodulin 3 (phosphorylase kinase, delta)	nucleoplasm	Cellular component	-
CYP17A1	1586	cytochrome P450, family 17, subfamily A, polypeptide 1	adrenal gland development	Biological process	-
CHRNG	1146	cholinergic receptor, nicotinic, gamma (muscle)	acetylcholine-activated cation-selective channel activity	Molecular function	-
MDFIC	29969	MyoD family inhibitor domain containing	nucleus	Cellular component	10671520
DRD2	1813	dopamine receptor D2	dopamine binding	Molecular function	-
EFNB3	1949	ephrin-B3	ephrin receptor binding	Molecular function	8808709
GMPR	2766	guanosine monophosphate reductase	purine-containing compound salvage	Biological process	-
IL12B	3593	interleukin 12B	positive regulation of T-helper 17 type immune response	Biological process	-
IL10	3586	interleukin 10	interleukin-10 receptor binding	Molecular function	1847510
PUS1	80324	pseudouridylate synthase 1	poly(A) RNA binding	Molecular function	22658674
RER1	11079	retention in endoplasmic reticulum sorting receptor 1	positive regulation of establishment of protein localization to plasma membrane	Biological process	-
GRIK3	2899	glutamate receptor, ionotropic, kainate 3	perikaryon	Cellular component	-
RAD23A	5886	RAD23 homolog A (S. cerevisiae)	protein binding	Molecular function	10488153
PXK	54899	PX domain containing serine/threonine kinase	negative regulation of ion transport	Biological process	16135750
CAMK2A	815	calcium/calmodulin-dependent protein kinase II alpha	protein homodimerization activity	Molecular function	20668654
ADRB3	155	adrenoceptor beta 3	heat generation	Biological process	-
ASXL2	55252	additional sex combs like transcriptional regulator 2	nuclear chromatin	Cellular component	-
KCNJ9	3765	potassium channel, inwardly rectifying subfamily J, member 9	regulation of ion transmembrane transport	Biological process	-
ZSCAN20	7579	zinc finger and SCAN domain containing 20	transcription, DNA-templated	Biological process	-
C17orf85	55421	chromosome 17 open reading frame 85	nucleotide binding	Molecular function	-
PATZ1	23598	POZ (BTB) and AT hook containing zinc finger 1	nucleus	Cellular component	10713105
MAVS	57506	mitochondrial antiviral signaling protein	positive regulation of protein phosphorylation	Biological process	16127453
GFAP	2670	glial fibrillary acidic protein	astrocyte end-foot	Cellular component	-
KCNK3	3777	potassium channel, two pore domain subfamily K, member 3	response to drug	Biological process	-
TP53BP1	7158	tumor protein p53 binding protein 1	p53 binding	Molecular function	14985081
PAX3	5077	paired box 3	protein binding	Molecular function	11029584
NEB	4703	nebulin	muscle organ development	Biological process	7739042
CEP164	22897	centrosomal protein 164kDa	G2/M transition of mitotic cell cycle	Biological process	-
RPA3	6119	replication protein A3, 14kDa	base-excision repair	Biological process	-
CCL23	6368	chemokine (C-C motif) ligand 23	immune response	Biological process	-
UBQLN1	29979	ubiquilin 1	protein domain specific binding	Molecular function	-
APOE	348	apolipoprotein E	neuronal cell body	Cellular component	8083695
STK40	83931	serine/threonine kinase 40	glycogen metabolic process	Biological process	-
DMC1	11144	DNA meiotic recombinase 1	spermatid development	Biological process	-
HIST2H2AA4	723790	histone cluster 2, H2aa4	nucleus	Cellular component	16319397
SF1	7536	splicing factor 1	transcription corepressor activity	Molecular function	9660765
ACVR1	90	activin A receptor, type I	negative regulation of extrinsic apoptotic signaling pathway	Biological process	9884026
CREB3L1	90993	cAMP responsive element binding protein 3-like 1	integral component of membrane	Cellular component	-
TOPORS	10210	topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase	PML body	Cellular component	21159800
DGAT2L7P	646409	diacylglycerol O-acyltransferase 2-like 7, pseudogene	lipid metabolic process	Biological process	-
MRPS7	51081	mitochondrial ribosomal protein S7	poly(A) RNA binding	Molecular function	22658674
NEK10	152110	NIMA-related kinase 10	protein kinase complex	Cellular component	20956560
TFAP2A	7020	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	cellular response to iron ion	Biological process	20808827
P2RX7	5027	purinergic receptor P2X, ligand gated ion channel, 7	response to drug	Biological process	-
SPANXD	64648	SPANX family, member D	cytoplasm	Cellular component	-
GHRL	51738	ghrelin/obestatin prepropeptide	positive regulation of corticotropin secretion	Biological process	12566947
COPA	1314	coatomer protein complex, subunit alpha	COPI vesicle coat	Cellular component	-
HIST4H4	121504	histone cluster 4, H4	protein heterodimerization activity	Molecular function	-
JAK3	3718	Janus kinase 3	extrinsic component of cytoplasmic side of plasma membrane	Cellular component	-
PPP3CB	5532	protein phosphatase 3, catalytic subunit, beta isozyme	protein phosphorylation	Biological process	-
SEMA4C	54910	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C	semaphorin-plexin signaling pathway	Biological process	-
ATXN1	6310	ataxin 1	nucleoplasm	Cellular component	-
MRPL16	54948	mitochondrial ribosomal protein L16	structural constituent of ribosome	Molecular function	-
INSRR	3645	insulin receptor-related receptor	cellular response to alkaline pH	Biological process	21641549
GRM5	2915	glutamate receptor, metabotropic 5	regulation of synaptic transmission, glutamatergic	Biological process	-
SETBP1	26040	SET binding protein 1	protein binding	Molecular function	25416956
ATG2B	55102	autophagy related 2B	mitochondrion degradation	Biological process	-
DLX5	1749	distal-less homeobox 5	epithelial cell differentiation	Biological process	-
USP19	10869	ubiquitin specific peptidase 19	endoplasmic reticulum membrane	Cellular component	19465887
OR7C2	26658	olfactory receptor, family 7, subfamily C, member 2	G-protein coupled receptor signaling pathway	Biological process	-
HNRNPUL1	11100	heterogeneous nuclear ribonucleoprotein U-like 1	RNA binding	Molecular function	9733834
UCHL5	51377	ubiquitin carboxyl-terminal hydrolase L5	negative regulation of endopeptidase activity	Biological process	18162577
OTUD6B	51633	OTU domain containing 6B	cysteine-type peptidase activity	Molecular function	-
MED6	10001	mediator complex subunit 6	membrane	Cellular component	19946888
PSMC3	5702	proteasome (prosome, macropain) 26S subunit, ATPase, 3	transcription coactivator activity	Molecular function	8419915
MAP2K2	5605	mitogen-activated protein kinase kinase 2	nucleus	Cellular component	19565474
EHMT2	10919	euchromatic histone-lysine N-methyltransferase 2	histone H3-K9 methylation	Biological process	-
EFNB3	1949	ephrin-B3	transmembrane-ephrin receptor activity	Molecular function	9126477
TNFRSF10D	8793	tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain	TRAIL binding	Molecular function	-
SDR9C7	121214	short chain dehydrogenase/reductase family 9C, member 7	oxidation-reduction process	Biological process	19703561
SLC2A11	66035	solute carrier family 2 (facilitated glucose transporter), member 11	plasma membrane	Cellular component	-
RNF40	9810	ring finger protein 40, E3 ubiquitin protein ligase	protein homodimerization activity	Molecular function	10944455
PIGH	5283	phosphatidylinositol glycan anchor biosynthesis, class H	endoplasmic reticulum membrane	Cellular component	-
NPC2	10577	Niemann-Pick disease, type C2	enzyme binding	Molecular function	15110773
PPP1R10	5514	protein phosphatase 1, regulatory subunit 10	metal ion binding	Molecular function	-
PKD1L2	114780	polycystic kidney disease 1-like 2 (gene/pseudogene)	calcium ion binding	Molecular function	-
CHD7	55636	chromodomain helicase DNA binding protein 7	protein binding	Molecular function	20453063
SPON1	10418	spondin 1, extracellular matrix protein	endoplasmic reticulum lumen	Cellular component	-
HIGD1B	51751	HIG1 hypoxia inducible domain family, member 1B	integral component of membrane	Cellular component	-
TNPO1	3842	transportin 1	gene expression	Biological process	-
CAV1	857	caveolin 1, caveolae protein, 22kDa	endocytic vesicle membrane	Cellular component	-
IRAK1	3654	interleukin-1 receptor-associated kinase 1	toll-like receptor 3 signaling pathway	Biological process	-
TMEM256	254863	transmembrane protein 256	molecular_function	Molecular function	-
PPP2R5E	5529	protein phosphatase 2, regulatory subunit B', epsilon isoform	regulation of protein phosphatase type 2A activity	Biological process	8703017
FIGLA	344018	folliculogenesis specific basic helix-loop-helix	protein dimerization activity	Molecular function	-
ACAA1	30	acetyl-CoA acyltransferase 1	peroxisome	Cellular component	1347505
DNALI1	7802	dynein, axonemal, light intermediate chain 1	movement of cell or subcellular component	Biological process	9284741
HMGA2	8091	high mobility group AT-hook 2	positive regulation of transcription, DNA-templated	Biological process	17624332
LYN	4067	LYN proto-oncogene, Src family tyrosine kinase	positive regulation of oligodendrocyte progenitor proliferation	Biological process	-
KMT2D	8085	lysine (K)-specific methyltransferase 2D	oogenesis	Biological process	-
CHST7	56548	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7	glycosaminoglycan metabolic process	Biological process	-
OLA1	29789	Obg-like ATPase 1	ATPase activity	Molecular function	17430889
CTSE	1510	cathepsin E	protein homodimerization activity	Molecular function	-
KHDRBS2	202559	KH domain containing, RNA binding, signal transduction associated 2	protein binding	Molecular function	16189514
F2R	2149	coagulation factor II (thrombin) receptor	caveola	Cellular component	17848177
MC5R	4161	melanocortin 5 receptor	protein binding	Molecular function	19329486
TNNT2	7139	troponin T type 2 (cardiac)	response to calcium ion	Biological process	8205619
OR8D1	283159	olfactory receptor, family 8, subfamily D, member 1	G-protein coupled receptor activity	Molecular function	-
DPY30	84661	dpy-30 homolog (C. elegans)	identical protein binding	Molecular function	16189514
AZIN2	113451	antizyme inhibitor 2	endoplasmic reticulum-Golgi intermediate compartment membrane	Cellular component	-
MOGS	7841	mannosyl-oligosaccharide glucosidase	protein N-linked glycosylation via asparagine	Biological process	-
HTN1	3346	histatin 1	killing of cells of other organism	Biological process	-
ERVK-6	64006	endogenous retrovirus group K, member 6	dUTP metabolic process	Biological process	-
KLF7	8609	Kruppel-like factor 7 (ubiquitous)	axon guidance	Biological process	-
AZIN1	51582	antizyme inhibitor 1	cellular nitrogen compound metabolic process	Biological process	-
SHOX2	6474	short stature homeobox 2	cardiac atrium morphogenesis	Biological process	-
ELF1	1997	E74-like factor 1 (ets domain transcription factor)	nucleoplasm	Cellular component	-
TMEM126A	84233	transmembrane protein 126A	optic nerve development	Biological process	19327736
FGF2	2247	fibroblast growth factor 2 (basic)	branching involved in ureteric bud morphogenesis	Biological process	12631064
SREBF1	6720	sterol regulatory element binding transcription factor 1	positive regulation of histone deacetylation	Biological process	-
CHIT1	1118	chitinase 1 (chitotriosidase)	chitin catabolic process	Biological process	9748235
GPT2	84706	glutamic pyruvate transaminase (alanine aminotransferase) 2	2-oxoglutarate metabolic process	Biological process	11863375
ELL2	22936	elongation factor, RNA polymerase II, 2	centrosome	Cellular component	-
RAB32	10981	RAB32, member RAS oncogene family	antigen processing and presentation	Biological process	19717423
NEURL1	9148	neuralized E3 ubiquitin protein ligase 1	positive regulation of long-term neuronal synaptic plasticity	Biological process	-
FRS2	10818	fibroblast growth factor receptor substrate 2	organ induction	Biological process	-
FLRT2	23768	fibronectin leucine rich transmembrane protein 2	axon guidance	Biological process	-
SCX	642658	scleraxis basic helix-loop-helix transcription factor	endochondral ossification	Biological process	-
PPIL2	23759	peptidylprolyl isomerase (cyclophilin)-like 2	ubiquitin-ubiquitin ligase activity	Molecular function	11435423
MKX	283078	mohawk homeobox	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
DSC1	1823	desmocollin 1	gap junction	Cellular component	7679953
ABCB9	23457	ATP-binding cassette, sub-family B (MDR/TAP), member 9	peptide-transporting ATPase activity	Molecular function	17977821
UQCC1	55245	ubiquinol-cytochrome c reductase complex assembly factor 1	mitochondrial respiratory chain complex III assembly	Biological process	24385928
FAU	2197	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed	translational initiation	Biological process	-
PODXL	5420	podocalyxin-like	epithelial tube formation	Biological process	-
PDPN	10630	podoplanin	water channel activity	Molecular function	-
ZNF799	90576	zinc finger protein 799	DNA binding	Molecular function	-
ATP1A4	480	ATPase, Na+/K+ transporting, alpha 4 polypeptide	sodium ion transport	Biological process	7809153
SLC35D1	23169	solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1	antiporter activity	Molecular function	-
ALOX12	239	arachidonate 12-lipoxygenase	lipoxin metabolic process	Biological process	-
CTC1	80169	CTS telomere maintenance complex component 1	nuclear chromosome, telomeric region	Cellular component	19854130
FAM129A	116496	family with sequence similarity 129, member A	molecular_function	Molecular function	-
NBEA	26960	neurobeachin	protein localization	Biological process	-
IPO9	55705	importin 9	membrane	Cellular component	19946888
FOXD1	2297	forkhead box D1	DNA binding, bending	Molecular function	7957066
MTMR9	66036	myotubularin related protein 9	cytoplasm	Cellular component	-
TIAF1	9220	TGFB1-induced anti-apoptotic factor 1	apoptotic process	Biological process	-
BTRC	8945	beta-transducin repeat containing E3 ubiquitin protein ligase	mammary gland epithelial cell proliferation	Biological process	-
CACNA1A	773	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	cytoplasm	Cellular component	16595610
ZNF280C	55609	zinc finger protein 280C	metal ion binding	Molecular function	-
DOCK1	1793	dedicator of cytokinesis 1	cell migration	Biological process	-
C11orf31	280636	chromosome 11 open reading frame 31	cell	Cellular component	-
GLCE	26035	glucuronic acid epimerase	UDP-glucuronate 5'-epimerase activity	Molecular function	15853773
GJA10	84694	gap junction protein, alpha 10, 62kDa	transmembrane transport	Biological process	-
DDX3X	1654	DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked	intracellular signal transduction	Biological process	18636090
LRP4	4038	low density lipoprotein receptor-related protein 4	Wnt signaling pathway involved in dorsal/ventral axis specification	Biological process	-
ELAC2	60528	elaC ribonuclease Z 2	nucleus	Cellular component	21593607
HEPH	9843	hephaestin	oxidation-reduction process	Biological process	-
ZAR1	326340	zygote arrest 1	multicellular organismal development	Biological process	-
ZMYM6	9204	zinc finger, MYM-type 6	cytoskeleton organization	Biological process	21834987
CYP2D6	1565	cytochrome P450, family 2, subfamily D, polypeptide 6	isoquinoline alkaloid metabolic process	Biological process	19448135
S1PR2	9294	sphingosine-1-phosphate receptor 2	G-protein coupled receptor signaling pathway	Biological process	10617617
AARS2	57505	alanyl-tRNA synthetase 2, mitochondrial	mitochondrion	Cellular component	-
RAB43	339122	RAB43, member RAS oncogene family	intracellular protein transport	Biological process	-
TIMM10B	26515	translocase of inner mitochondrial membrane 10 homolog B (yeast)	cell-matrix adhesion	Biological process	9731230
BRD7	29117	bromodomain containing 7	regulation of transcription from RNA polymerase II promoter	Biological process	12489984
SLC9B1	150159	solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1	solute:proton antiporter activity	Molecular function	-
KRT36	8689	keratin 36, type I	intermediate filament	Cellular component	-
NAGLU	4669	N-acetylglucosaminidase, alpha	retinal rod cell development	Biological process	-
LAMC3	10319	laminin, gamma 3	extracellular matrix organization	Biological process	-
OR10K2	391107	olfactory receptor, family 10, subfamily K, member 2	G-protein coupled receptor activity	Molecular function	-
ANKRD26	22852	ankyrin repeat domain 26	negative regulation of insulin receptor signaling pathway	Biological process	-
RHEB	6009	Ras homolog enriched in brain	membrane	Cellular component	8206940
GABRD	2563	gamma-aminobutyric acid (GABA) A receptor, delta	signal transduction	Biological process	2176788
DLD	1738	dihydrolipoamide dehydrogenase	cellular metabolic process	Biological process	-
PRDM9	56979	PR domain containing 9	histone H3-K4 methylation	Biological process	-
ADCK2	90956	aarF domain containing kinase 2	protein phosphorylation	Biological process	-
WDR11	55717	WD repeat domain 11	cilium	Cellular component	-
RFXANK	8625	regulatory factor X-associated ankyrin-containing protein	DNA binding	Molecular function	-
ARHGEF2	9181	Rho/Rac guanine nucleotide exchange factor (GEF) 2	positive regulation of interleukin-6 production	Biological process	21887730
PLOD3	8985	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3	endoplasmic reticulum	Cellular component	9724729
ACVR1	90	activin A receptor, type I	transforming growth factor beta receptor signaling pathway	Biological process	8242742
GALNT11	63917	polypeptide N-acetylgalactosaminyltransferase 11	integral component of membrane	Cellular component	-
PPP2R4	5524	protein phosphatase 2A activator, regulatory subunit 4	positive regulation of phosphoprotein phosphatase activity	Biological process	16916641
SLC16A10	117247	solute carrier family 16 (aromatic amino acid transporter), member 10	aromatic amino acid transmembrane transporter activity	Molecular function	-
TFAP2B	7021	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	skin development	Biological process	-
AP1G2	8906	adaptor-related protein complex 1, gamma 2 subunit	intracellular protein transport	Biological process	-
SRC	6714	SRC proto-oncogene, non-receptor tyrosine kinase	integrin binding	Molecular function	19267251
RAB40C	57799	RAB40C, member RAS oncogene family	GDP binding	Molecular function	-
NEK7	140609	NIMA-related kinase 7	regulation of signal transduction	Biological process	-
TAB2	23118	TGF-beta activated kinase 1/MAP3K7 binding protein 2	stimulatory C-type lectin receptor signaling pathway	Biological process	-
LIFR	3977	leukemia inhibitory factor receptor alpha	cytokine-mediated signaling pathway	Biological process	7957045
FLT3	2322	fms-related tyrosine kinase 3	vascular endothelial growth factor signaling pathway	Biological process	8394751
PTPRM	5797	protein tyrosine phosphatase, receptor type, M	integral component of plasma membrane	Cellular component	1655529
FOXO1	2308	forkhead box O1	Fc-epsilon receptor signaling pathway	Biological process	-
PBRM1	55193	polybromo 1	chromatin binding	Molecular function	11078522
WDFY3	23001	WD repeat and FYVE domain containing 3	nuclear envelope	Cellular component	15292400
TRAPPC3	27095	trafficking protein particle complex 3	vesicle-mediated transport	Biological process	-
CALM2	805	calmodulin 2 (phosphorylase kinase, delta)	positive regulation of protein serine/threonine kinase activity	Biological process	20668654
C2CD2L	9854	C2CD2-like	biological_process	Biological process	-
NEK5	341676	NIMA-related kinase 5	protein serine/threonine kinase activity	Molecular function	-
ALPI	248	alkaline phosphatase, intestinal	protein binding	Molecular function	25416956
PCK1	5105	phosphoenolpyruvate carboxykinase 1 (soluble)	response to insulin	Biological process	14764811
ACY3	91703	aminoacylase 3	protein binding	Molecular function	21516116
PRAMEF16	654348	PRAME family member 16	negative regulation of cell differentiation	Biological process	-
OPHN1	4983	oligophrenin 1	ionotropic glutamate receptor binding	Molecular function	-
SPRY2	10253	sprouty homolog 2 (Drosophila)	negative regulation of Ras protein signal transduction	Biological process	-
PSG2	5670	pregnancy specific beta-1-glycoprotein 2	extracellular region	Cellular component	-
KLRC1	3821	killer cell lectin-like receptor subfamily C, member 1	transmembrane signaling receptor activity	Molecular function	2007850
LMAN1	3998	lectin, mannose-binding, 1	protein folding	Biological process	9546392
RPGRIP1L	23322	RPGRIP1-like	protein binding	Molecular function	17558407
NFKBIL1	4795	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1	I-kappaB kinase/NF-kappaB signaling	Biological process	-
SGCE	8910	sarcoglycan, epsilon	dystrophin-associated glycoprotein complex	Cellular component	17993586
SLC28A3	64078	solute carrier family 28 (concentrative nucleoside transporter), member 3	transmembrane transport	Biological process	-
ADCY4	196883	adenylate cyclase 4	synaptic transmission	Biological process	-
ATOH7	220202	atonal homolog 7 (Drosophila)	neural retina development	Biological process	21441919
AGAP4	119016	ArfGAP with GTPase domain, ankyrin repeat and PH domain 4	metal ion binding	Molecular function	-
LAMP2	3920	lysosomal-associated membrane protein 2	late endosome	Cellular component	15229288
ACE2	59272	angiotensin I converting enzyme 2	peptidyl-dipeptidase activity	Molecular function	10924499
SPTLC1	10558	serine palmitoyltransferase, long chain base subunit 1	ceramide biosynthetic process	Biological process	-
RBBP8	5932	retinoblastoma binding protein 8	nucleolus	Cellular component	-
PAK3	5063	p21 protein (Cdc42/Rac)-activated kinase 3	MAP kinase kinase activity	Molecular function	21177870
ELANE	1991	elastase, neutrophil expressed	protein binding	Molecular function	12114510
PRLHR	2834	prolactin releasing hormone receptor	G-protein coupled receptor activity	Molecular function	8666380
SPG7	6687	spastic paraplegia 7 (pure and complicated autosomal recessive)	integral component of membrane	Cellular component	-
LRP8	7804	low density lipoprotein receptor-related protein 8, apolipoprotein e receptor	postsynaptic density	Cellular component	-
CEP128	145508	centrosomal protein 128kDa	spindle pole	Cellular component	21399614
COLGALT2	23127	collagen beta(1-O)galactosyltransferase 2	endoplasmic reticulum lumen	Cellular component	-
WBP11	51729	WW domain binding protein 11	mRNA processing	Biological process	-
SDC3	9672	syndecan 3	carbohydrate metabolic process	Biological process	-
TFAP2B	7021	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	phosphate ion homeostasis	Biological process	-
HOOK3	84376	hook microtubule-tethering protein 3	early endosome to late endosome transport	Biological process	18799622
CEMIP	57214	cell migration inducing protein, hyaluronan binding	hyaluronic acid binding	Molecular function	23509262
HLA-E	3133	major histocompatibility complex, class I, E	MHC class I protein complex	Cellular component	12411439
RAC1	5879	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	positive regulation of focal adhesion assembly	Biological process	23129259
MAVS	57506	mitochondrial antiviral signaling protein	regulation of peroxisome organization	Biological process	20451243
PARK2	5071	parkin RBR E3 ubiquitin protein ligase	cytosol	Cellular component	21508222
PRKCI	5584	protein kinase C, iota	cytoplasm	Cellular component	-
HAPLN1	1404	hyaluronan and proteoglycan link protein 1	central nervous system development	Biological process	-
NACC1	112939	nucleus accumbens associated 1, BEN and BTB (POZ) domain containing	cytoplasm	Cellular component	-
DAG1	1605	dystroglycan 1 (dystrophin-associated glycoprotein 1)	lamellipodium	Cellular component	18341635
GABRA2	2555	gamma-aminobutyric acid (GABA) A receptor, alpha 2	synaptic transmission	Biological process	-
SLC2A1	6513	solute carrier family 2 (facilitated glucose transporter), member 1	plasma membrane	Cellular component	-
EPB41L5	57669	erythrocyte membrane protein band 4.1 like 5	mesoderm migration involved in gastrulation	Biological process	-
MOV10L1	54456	Mov10 RISC complex RNA helicase like 1	gene expression	Biological process	-
SLC25A20	788	solute carrier family 25 (carnitine/acylcarnitine translocase), member 20	small molecule metabolic process	Biological process	-
RGSL1	353299	regulator of G-protein signaling like 1	cytoplasm	Cellular component	-
ISG20	3669	interferon stimulated exonuclease gene 20kDa	exonuclease activity	Molecular function	21036379
ITGB1BP1	9270	integrin beta 1 binding protein 1	GDP-dissociation inhibitor activity	Molecular function	11807099
NME7	29922	NME/NM23 family member 7	intracellular	Cellular component	-
STT3B	201595	STT3B, subunit of the oligosaccharyltransferase complex (catalytic)	oligosaccharyltransferase complex	Cellular component	19167329
RAB33B	83452	RAB33B, member RAS oncogene family	regulation of cell growth	Biological process	20163571
ATXN7	6314	ataxin 7	microtubule cytoskeleton organization	Biological process	22100762
AURKAIP1	54998	aurora kinase A interacting protein 1	mitochondrion	Cellular component	-
PRNP	5621	prion protein	plasma membrane	Cellular component	-
PKP2	5318	plakophilin 2	cardiac muscle cell action potential	Biological process	-
KLHL20	27252	kelch-like family member 20	protein transport	Biological process	-
USP17L19	100287404	ubiquitin specific peptidase 17-like family member 19	ubiquitin-specific protease activity	Molecular function	-
FYCO1	79443	FYVE and coiled-coil domain containing 1	lysosome	Cellular component	20100911
KMT2A	4297	lysine (K)-specific methyltransferase 2A	unmethylated CpG binding	Molecular function	16990798
UBA52	7311	ubiquitin A-52 residue ribosomal protein fusion product 1	G2/M transition of mitotic cell cycle	Biological process	-
SETD2	29072	SET domain containing 2	embryonic cranial skeleton morphogenesis	Biological process	-
APOF	319	apolipoprotein F	cholesterol metabolic process	Biological process	-
CBLN4	140689	cerebellin 4 precursor	cell junction	Cellular component	-
HAO1	54363	hydroxyacid oxidase (glycolate oxidase) 1	peroxisomal matrix	Cellular component	-
SESN2	83667	sestrin 2	mitochondrion	Cellular component	-
FUT8	2530	fucosyltransferase 8 (alpha (1,6) fucosyltransferase)	receptor metabolic process	Biological process	-
S100A10	6281	S100 calcium binding protein A10	positive regulation of binding	Biological process	-
NOS1	4842	nitric oxide synthase 1 (neuronal)	photoreceptor inner segment	Cellular component	17027776
SLC37A1	54020	solute carrier family 37 (glucose-6-phosphate transporter), member 1	carbohydrate transport	Biological process	-
ZXDA	7789	zinc finger, X-linked, duplicated A	nucleic acid binding	Molecular function	-
PTEN	5728	phosphatase and tensin homolog	synapse maturation	Biological process	-
NT5DC4	284958	5'-nucleotidase domain containing 4	dephosphorylation	Biological process	-
PCCB	5096	propionyl CoA carboxylase, beta polypeptide	fatty acid beta-oxidation	Biological process	-
SLC10A4	201780	solute carrier family 10, member 4	bile acid:sodium symporter activity	Molecular function	-
APOC3	345	apolipoprotein C-III	early endosome	Cellular component	-
SKIV2L	6499	superkiller viralicidic activity 2-like (S. cerevisiae)	ATP-dependent RNA helicase activity	Molecular function	7610041
CIB1	10519	calcium and integrin binding 1 (calmyrin)	ruffle membrane	Cellular component	-
CREM	1390	cAMP responsive element modulator	cell differentiation	Biological process	-
DLX2	1746	distal-less homeobox 2	sequence-specific DNA binding transcription factor activity	Molecular function	1354641
NKX2-5	1482	NK2 homeobox 5	positive regulation of transcription, DNA-templated	Biological process	8900537
VAV3	10451	vav 3 guanine nucleotide exchange factor	positive regulation of cell adhesion	Biological process	-
CHPT1	56994	choline phosphotransferase 1	membrane	Cellular component	10893425
IFI16	3428	interferon, gamma-inducible protein 16	cellular response to ionizing radiation	Biological process	14654789
RASSF2	9770	Ras association (RalGDS/AF-6) domain family member 2	ossification	Biological process	-
GRIK2	2898	glutamate receptor, ionotropic, kainate 2	transport	Biological process	7536611
NXT1	29107	nuclear transport factor 2-like export factor 1	protein export from nucleus	Biological process	-
PSMB9	5698	proteasome (prosome, macropain) subunit, beta type, 9	antigen processing and presentation of exogenous peptide antigen via MHC class I	Biological process	-
BCAP31	10134	B-cell receptor-associated protein 31	positive regulation of cytosolic calcium ion concentration	Biological process	21183955
LMAN2	10960	lectin, mannose-binding 2	extracellular space	Cellular component	22016386
PIF1	80119	PIF1 5'-to-3' DNA helicase	nuclear chromosome, telomeric region	Cellular component	16522649
COLEC12	81035	collectin sub-family member 12	low-density lipoprotein particle binding	Molecular function	11564734
PRELID1	27166	PRELI domain containing 1	positive regulation of T cell apoptotic process	Biological process	18945965
IFNA5	3442	interferon, alpha 5	response to exogenous dsRNA	Biological process	-
RAPGEF2	9693	Rap guanine nucleotide exchange factor (GEF) 2	phosphatidic acid binding	Molecular function	22797597
DUSP10	11221	dual specificity phosphatase 10	cytoplasm	Cellular component	10391943
ENDOU	8909	endonuclease, polyU-specific	serine-type peptidase activity	Molecular function	18936097
P2RY1	5028	purinergic receptor P2Y, G-protein coupled, 1	scaffold protein binding	Molecular function	-
C17orf49	124944	chromosome 17 open reading frame 49	NURF complex	Cellular component	20850016
C1QA	712	complement component 1, q subcomponent, A chain	complement component C1 complex	Cellular component	9461517
LBP	3929	lipopolysaccharide binding protein	negative regulation of tumor necrosis factor production	Biological process	11739189
PSEN2	5664	presenilin 2	cytosol	Cellular component	-
AKR1C1	1645	aldo-keto reductase family 1, member C1	protein binding	Molecular function	25416956
CARD9	64170	caspase recruitment domain family, member 9	regulation of interleukin-2 biosynthetic process	Biological process	-
ZFP64	55734	ZFP64 zinc finger protein	positive regulation of mRNA splicing, via spliceosome	Biological process	-
NEU4	129807	sialidase 4	oligosaccharide catabolic process	Biological process	15213228
NUP50	10762	nucleoporin 50kDa	cellular protein metabolic process	Biological process	-
CRH	1392	corticotropin releasing hormone	locomotory exploration behavior	Biological process	-
SLC11A1	6556	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1	positive regulation of gene expression	Biological process	-
RHOH	399	ras homolog family member H	cytoplasm	Cellular component	11809807
MARVELD3	91862	MARVEL domain containing 3	bicellular tight junction assembly	Biological process	20164257
PVRL3	25945	poliovirus receptor-related 3	integral component of membrane	Cellular component	-
MSH5	4439	mutS homolog 5	homologous chromosome segregation	Biological process	-
NLGN1	22871	neuroligin 1	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	Biological process	-
CNDP1	84735	carnosine dipeptidase 1 (metallopeptidase M20 family)	metallopeptidase activity	Molecular function	-
SNRPD3	6634	small nuclear ribonucleoprotein D3 polypeptide 18kDa	protein methylation	Biological process	18495660
NKX1-1	54729	NK1 homeobox 1	regulation of glucose metabolic process	Biological process	-
THG1L	54974	tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)	tRNA guanylyltransferase activity	Molecular function	-
P2RX7	5027	purinergic receptor P2X, ligand gated ion channel, 7	sensory perception of pain	Biological process	-
GRAP2	9402	GRB2-related adaptor protein 2	nucleoplasm	Cellular component	-
SIK1	150094	salt-inducible kinase 1	regulation of myotube differentiation	Biological process	-
PARD6A	50855	par-6 family cell polarity regulator alpha	protein complex	Cellular component	-
CRK	1398	v-crk avian sarcoma virus CT10 oncogene homolog	activation of MAPKK activity	Biological process	-
ZMIZ1	57178	zinc finger, MIZ-type containing 1	nucleoplasm	Cellular component	-
TMOD1	7111	tropomodulin 1	cytosol	Cellular component	-
PPARD	5467	peroxisome proliferator-activated receptor delta	glucose metabolic process	Biological process	15793256
MTOR	2475	mechanistic target of rapamycin (serine/threonine kinase)	response to amino acid	Biological process	18497260
ST7	7982	suppression of tumorigenicity 7	integral component of membrane	Cellular component	-
PTPN20	26095	protein tyrosine phosphatase, non-receptor type 20	microtubule organizing center	Cellular component	-
SRC	6714	SRC proto-oncogene, non-receptor tyrosine kinase	negative regulation of protein homooligomerization	Biological process	19767770
DDX19B	11269	DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B	protein transport	Biological process	-
REXO1L1P	254958	REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 1, pseudogene	cytoplasm	Cellular component	-
RXFP3	51289	relaxin/insulin-like family peptide receptor 3	cytosol	Cellular component	-
BAHD1	22893	bromo adjacent homology domain containing 1	transcription, DNA-templated	Biological process	-
HOXB3	3213	homeobox B3	face development	Biological process	-
TNKS	8658	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase	positive regulation of telomere maintenance via telomerase	Biological process	11739745
AGAP9	642517	ArfGAP with GTPase domain, ankyrin repeat and PH domain 9	metal ion binding	Molecular function	-
PIAS1	8554	protein inhibitor of activated STAT, 1	interferon-gamma-mediated signaling pathway	Biological process	-
WNT2B	7482	wingless-type MMTV integration site family, member 2B	lens development in camera-type eye	Biological process	16258938
NPAT	4863	nuclear protein, ataxia-telangiectasia locus	cytoplasm	Cellular component	17068332
S100A7	6278	S100 calcium binding protein A7	response to lipopolysaccharide	Biological process	17625598
IKBKE	9641	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	innate immune response	Biological process	-
HIST1H4D	8360	histone cluster 1, H4d	nucleoplasm	Cellular component	-
TFR2	7036	transferrin receptor 2	transferrin receptor activity	Molecular function	10409623
CLSTN1	22883	calsyntenin 1	cell adhesion	Biological process	17332754
NACA	4666	nascent polypeptide-associated complex alpha subunit	DNA binding	Molecular function	-
METTL1	4234	methyltransferase like 1	nucleus	Cellular component	-
ICAM3	3385	intercellular adhesion molecule 3	integrin binding	Molecular function	1448173
NPBWR1	2831	neuropeptides B/W receptor 1	G-protein coupled receptor signaling pathway	Biological process	12401809
CHM	1121	choroideremia (Rab escort protein 1)	Rab-protein geranylgeranyltransferase complex	Cellular component	7957092
BAG3	9531	BCL2-associated athanogene 3	protein folding	Biological process	9873016
BCL2	596	B-cell CLL/lymphoma 2	cell growth	Biological process	-
ISCA2	122961	iron-sulfur cluster assembly 2	iron-sulfur cluster assembly	Biological process	-
VIM	7431	vimentin	muscle filament sliding	Biological process	-
ZNF683	257101	zinc finger protein 683	metal ion binding	Molecular function	-
IFNA17	3451	interferon, alpha 17	type I interferon receptor binding	Molecular function	3891272
IL1A	3552	interleukin 1, alpha	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	Biological process	10748004
STAR	6770	steroidogenic acute regulatory protein	response to nicotine	Biological process	-
SGOL1	151648	shugoshin-like 1 (S. pombe)	mitotic nuclear division	Biological process	-
ADGRA2	25960	adhesion G protein-coupled receptor A2	endothelial cell migration	Biological process	-
ARSG	22901	arylsulfatase G	glycosphingolipid metabolic process	Biological process	-
PUF60	22827	poly-U binding splicing factor 60KDa	mRNA processing	Biological process	-
OTOR	56914	otoraplin	extracellular region	Cellular component	-
HIST1H2BD	3017	histone cluster 1, H2bd	molecular_function	Molecular function	-
IL4	3565	interleukin 4	positive regulation of activated T cell proliferation	Biological process	-
DPYSL3	1809	dihydropyrimidinase-like 3	exocytic vesicle	Cellular component	-
DNALI1	7802	dynein, axonemal, light intermediate chain 1	axonemal dynein complex	Cellular component	9284741
SLA	6503	Src-like-adaptor	positive regulation of signal transduction	Biological process	7543898
GFI1B	8328	growth factor independent 1B transcription repressor	metal ion binding	Molecular function	-
CRYAA	1409	crystallin, alpha A	metal ion binding	Molecular function	-
USP24	23358	ubiquitin specific peptidase 24	cysteine-type endopeptidase activity	Molecular function	-
PIK3CB	5291	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta	plasma membrane	Cellular component	-
ZNF577	84765	zinc finger protein 577	nucleus	Cellular component	-
GAD2	2572	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)	clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane	Cellular component	-
RBM8A	9939	RNA binding motif protein 8A	nucleus	Cellular component	11013075
NAMPT	10135	nicotinamide phosphoribosyltransferase	signal transduction	Biological process	8289818
CAMK1	8536	calcium/calmodulin-dependent protein kinase I	nucleus	Cellular component	-
MMACHC	25974	methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria	protein binding	Molecular function	23825108
LRRK2	120892	leucine-rich repeat kinase 2	regulation of mitochondrial fission	Biological process	24252804
PPM1N	147699	protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)	manganese ion binding	Molecular function	-
PPM1A	5494	protein phosphatase, Mg2+/Mn2+ dependent, 1A	dephosphorylation	Biological process	10644691
ANKRD45	339416	ankyrin repeat domain 45	molecular_function	Molecular function	-
GLI1	2735	GLI family zinc finger 1	nucleus	Cellular component	10806483
XRN1	54464	5'-3' exoribonuclease 1	5'-3' exonuclease activity	Molecular function	-
RAB12	201475	RAB12, member RAS oncogene family	regulation of exocytosis	Biological process	-
RAB5A	5868	RAB5A, member RAS oncogene family	regulation of filopodium assembly	Biological process	14978216
PON1	5444	paraoxonase 1	aryldialkylphosphatase activity	Molecular function	15098021
SCO2	9997	SCO2 cytochrome c oxidase assembly protein	gene expression	Biological process	-
PTPRF	5792	protein tyrosine phosphatase, receptor type, F	heparin binding	Molecular function	-
ZNF675	171392	zinc finger protein 675	negative regulation of interleukin-1-mediated signaling pathway	Biological process	11751921
Mar-02	51257	membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase	cytoplasmic vesicle	Cellular component	14722266
DTD1	92675	D-tyrosyl-tRNA deacylase 1	tRNA metabolic process	Biological process	-
POLR3F	10621	polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa	gene expression	Biological process	-
APOC3	345	apolipoprotein C-III	negative regulation of lipoprotein lipase activity	Biological process	11060345
CD276	80381	CD276 molecule	T cell activation	Biological process	18650384
HEXB	3074	hexosaminidase B (beta polypeptide)	lipid storage	Biological process	-
OR9A2	135924	olfactory receptor, family 9, subfamily A, member 2	G-protein coupled receptor signaling pathway	Biological process	-
PTCH1	5727	patched 1	negative regulation of sequence-specific DNA binding transcription factor activity	Biological process	16229683
POLA2	23649	polymerase (DNA directed), alpha 2, accessory subunit	mitotic cell cycle	Biological process	-
PPP6C	5537	protein phosphatase 6, catalytic subunit	G1/S transition of mitotic cell cycle	Biological process	9013334
TBC1D10C	374403	TBC1 domain family, member 10C	negative regulation of B cell activation	Biological process	-
ADD1	118	adducin 1 (alpha)	perinuclear region of cytoplasm	Cellular component	-
NQO1	1728	NAD(P)H dehydrogenase, quinone 1	synaptic transmission, cholinergic	Biological process	9579781
HTRA2	27429	HtrA serine peptidase 2	endoplasmic reticulum membrane	Cellular component	10644717
SCFD1	23256	sec1 family domain containing 1	cell morphogenesis	Biological process	-
EDDM3B	64184	epididymal protein 3B	protein binding	Molecular function	25416956
ZNF736	728927	zinc finger protein 736	transcription, DNA-templated	Biological process	-
STX7	8417	syntaxin 7	SNARE binding	Molecular function	24550300
EGFR	1956	epidermal growth factor receptor	endosome	Cellular component	14702346
RIMS1	22999	regulating synaptic membrane exocytosis 1	synaptic transmission	Biological process	-
GPR37	2861	G protein-coupled receptor 37 (endothelin receptor type B-like)	protein binding	Molecular function	14532270
KIF28P	100130097	kinesin family member 28, pseudogene	microtubule binding	Molecular function	-
INHBB	3625	inhibin, beta B	hormone activity	Molecular function	3122219
TXN2	25828	thioredoxin 2	response to hormone	Biological process	-
RUVBL1	8607	RuvB-like AAA ATPase 1	protein binding	Molecular function	10966108
CNGB1	1258	cyclic nucleotide gated channel beta 1	intracellular cyclic nucleotide activated cation channel complex	Cellular component	-
ACAP2	23527	ArfGAP with coiled-coil, ankyrin repeat and PH domains 2	membrane	Cellular component	19946888
SLC38A3	10991	solute carrier family 38, member 3	symporter activity	Molecular function	-
ABCA1	19	ATP-binding cassette, sub-family A (ABC1), member 1	high-density lipoprotein particle assembly	Biological process	10431236
LSM6	11157	LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)	gene expression	Biological process	-
C4BPB	725	complement component 4 binding protein, beta	extracellular region	Cellular component	14718574
UGT2B4	7363	UDP glucuronosyltransferase 2 family, polypeptide B4	metabolic process	Biological process	8333863
WNT3	7473	wingless-type MMTV integration site family, member 3	positive regulation of collateral sprouting in absence of injury	Biological process	-
RBMY1B	378948	RNA binding motif protein, Y-linked, family 1, member B	RNA binding	Molecular function	9598316
SLC18A2	6571	solute carrier family 18 (vesicular monoamine transporter), member 2	membrane	Cellular component	8095030
ATP6V0A1	535	ATPase, H+ transporting, lysosomal V0 subunit a1	protein binding	Molecular function	12649290
ITGB1BP1	9270	integrin beta 1 binding protein 1	tube formation	Biological process	20616313
SMAD2	4087	SMAD family member 2	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	9389648
PCNA	5111	proliferating cell nuclear antigen	damaged DNA binding	Molecular function	24939902
NR3C2	4306	nuclear receptor subfamily 3, group C, member 2	steroid hormone receptor activity	Molecular function	-
FANCA	2175	Fanconi anemia, complementation group A	nucleoplasm	Cellular component	-
ZIM2	23619	zinc finger, imprinted 2	regulation of transcription from RNA polymerase II promoter	Biological process	-
RPL5	6125	ribosomal protein L5	viral process	Biological process	-
HYAL1	3373	hyaluronoglucosaminidase 1	cellular response to UV-B	Biological process	21699545
FKBP4	2288	FK506 binding protein 4, 59kDa	protein binding	Molecular function	12604780
ARHGEF2	9181	Rho/Rac guanine nucleotide exchange factor (GEF) 2	bicellular tight junction	Cellular component	-
USP17L6P	391622	ubiquitin specific peptidase 17-like family member 6, pseudogene	ubiquitin-dependent protein catabolic process	Biological process	-
PLBD2	196463	phospholipase B domain containing 2	lipid catabolic process	Biological process	-
KLHDC2	23588	kelch domain containing 2	nucleus	Cellular component	-
SCG2	7857	secretogranin II	endothelial cell migration	Biological process	9473216
METTL16	79066	methyltransferase like 16	23S rRNA (adenine(1618)-N(6))-methyltransferase activity	Molecular function	-
H2AFY2	55506	H2A histone family, member Y2	extracellular exosome	Cellular component	23376485
SFTPC	6440	surfactant protein C	circadian rhythm	Biological process	-
CHST3	9469	carbohydrate (chondroitin 6) sulfotransferase 3	chondroitin 6-sulfotransferase activity	Molecular function	9883891
DICER1	23405	dicer 1, ribonuclease type III	spleen development	Biological process	-
TAS1R1	80835	taste receptor, type 1, member 1	G-protein coupled receptor signaling pathway	Biological process	-
NARFL	64428	nuclear prelamin A recognition factor-like	oxygen homeostasis	Biological process	16956324
INHA	3623	inhibin, alpha	extracellular region	Cellular component	12456957
OR8U8	504189	olfactory receptor, family 8, subfamily U, member 8	integral component of membrane	Cellular component	-
CCL14	6358	chemokine (C-C motif) ligand 14	positive regulation of cell proliferation	Biological process	8551235
TMTC2	160335	transmembrane and tetratricopeptide repeat containing 2	protein binding	Molecular function	24764305
MINA	84864	MYC induced nuclear antigen	ribosome biogenesis	Biological process	-
PLP1	5354	proteolipid protein 1	integrin-mediated signaling pathway	Biological process	-
WNT8A	7478	wingless-type MMTV integration site family, member 8A	positive regulation of canonical Wnt signaling pathway	Biological process	-
VAMP7	6845	vesicle-associated membrane protein 7	vesicle fusion	Biological process	10888671
CREB1	1385	cAMP responsive element binding protein 1	negative regulation of transcription by competitive promoter binding	Biological process	19861239
GCLM	2730	glutamate-cysteine ligase, modifier subunit	glutamate metabolic process	Biological process	9841880
PIP5K1C	23396	phosphatidylinositol-4-phosphate 5-kinase, type I, gamma	small molecule metabolic process	Biological process	-
ADIPOR1	51094	adiponectin receptor 1	positive regulation of insulin receptor signaling pathway	Biological process	-
REC8	9985	REC8 meiotic recombination protein	male meiosis I	Biological process	-
SULT2A1	6822	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	cellular lipid metabolic process	Biological process	-
BRMS1L	84312	breast cancer metastasis-suppressor 1-like	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
EXT1	2131	exostosin glycosyltransferase 1	endoplasmic reticulum membrane	Cellular component	9620772
TAF11	6882	TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa	gene expression	Biological process	-
PAPOLG	64895	poly(A) polymerase gamma	membrane	Cellular component	19946888
BAG2	9532	BCL2-associated athanogene 2	protein metabolic process	Biological process	9873015
TP73-AS1	57212	TP73 antisense RNA 1	extracellular region	Cellular component	-
HMX1	3166	H6 family homeobox 1	multicellular organismal development	Biological process	-
NEBL	10529	nebulette	structural constituent of muscle	Molecular function	9733644
KIAA1804	84451	mixed lineage kinase 4	cellular_component	Cellular component	-
MCTS1	28985	malignant T cell amplified sequence 1	regulation of growth	Biological process	-
AMBN	258	ameloblastin (enamel matrix protein)	cell proliferation	Biological process	-
CEP57	9702	centrosomal protein 57kDa	microtubule binding	Molecular function	-
RPL37AP8	644338	ribosomal protein L37a pseudogene 8	translation	Biological process	-
CPZ	8532	carboxypeptidase Z	extracellular exosome	Cellular component	23376485
USP25	29761	ubiquitin specific peptidase 25	ubiquitin-specific protease activity	Molecular function	18538659
SMAD3	4088	SMAD family member 3	extrinsic apoptotic signaling pathway	Biological process	15334054
CDH18	1016	cadherin 18, type 2	cell junction assembly	Biological process	-
EDA	1896	ectodysplasin A	protein binding	Molecular function	11039935
FAM90A18P	441326	putative protein FAM90A18/FAM90A19	nucleic acid binding	Molecular function	-
GPD1L	23171	glycerol-3-phosphate dehydrogenase 1-like	glycerophospholipid biosynthetic process	Biological process	-
GJA3	2700	gap junction protein, alpha 3, 46kDa	integral component of membrane	Cellular component	-
TRAF4	9618	TNF receptor-associated factor 4	positive regulation of protein homodimerization activity	Biological process	16157600
PIK3R4	30849	phosphoinositide-3-kinase, regulatory subunit 4	protein phosphorylation	Biological process	8999962
LRP6	4040	low density lipoprotein receptor-related protein 6	external genitalia morphogenesis	Biological process	-
FGF23	8074	fibroblast growth factor 23	extracellular region	Cellular component	-
RND2	8153	Rho family GTPase 2	protein binding	Molecular function	12590651
LMBR1L	55716	limb development membrane protein 1-like	endocytosis	Biological process	-
THRB	7068	thyroid hormone receptor, beta	negative regulation of female receptivity	Biological process	-
HIST1H4H	8365	histone cluster 1, H4h	histone H4-K20 demethylation	Biological process	-
MGARP	84709	mitochondria-localized glutamic acid-rich protein	retrograde axon cargo transport	Biological process	-
COX4I2	84701	cytochrome c oxidase subunit IV isoform 2 (lung)	cytochrome-c oxidase activity	Molecular function	11311561
MYBPC3	4607	myosin binding protein C, cardiac	sarcomere organization	Biological process	-
DARS	1615	aspartyl-tRNA synthetase	cytosol	Cellular component	-
EIF4A2	1974	eukaryotic translation initiation factor 4A2	RNA secondary structure unwinding	Biological process	-
OR5L2	26338	olfactory receptor, family 5, subfamily L, member 2	G-protein coupled receptor activity	Molecular function	-
PRKCDBP	112464	protein kinase C, delta binding protein	positive regulation of ERK1 and ERK2 cascade	Biological process	-
IFT172	26160	intraflagellar transport 172	sperm cytoplasmic droplet	Cellular component	-
RPL23A	6147	ribosomal protein L23a	translational elongation	Biological process	-
TGFB1	7040	transforming growth factor, beta 1	glycoprotein binding	Molecular function	15247411
GHRL	51738	ghrelin/obestatin prepropeptide	positive regulation of cytosolic calcium ion concentration	Biological process	-
CADM1	23705	cell adhesion molecule 1	T cell mediated cytotoxicity	Biological process	15811952
LAMTOR5	10542	late endosomal/lysosomal adaptor, MAPK and MTOR activator 5	guanyl-nucleotide exchange factor activity	Molecular function	22980980
ITGAV	3685	integrin, alpha V	entry of symbiont into host cell by promotion of host phagocytosis	Biological process	10570297
TADA3	10474	transcriptional adaptor 3	Ada2/Gcn5/Ada3 transcription activator complex	Cellular component	18838386
PEF1	553115	penta-EF-hand domain containing 1	protein dimerization activity	Molecular function	11883899
RPSA	3921	ribosomal protein SA	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Biological process	-
STX12	23673	syntaxin 12	SNARE binding	Molecular function	-
PLIN3	10226	perilipin 3	Golgi apparatus	Cellular component	9590177
SLC23A1	9963	solute carrier family 23 (ascorbic acid transporter), member 1	sodium ion transmembrane transport	Biological process	18094143
DGKZ	8525	diacylglycerol kinase, zeta	lipid phosphorylation	Biological process	16286473
EIF4A1	1973	eukaryotic translation initiation factor 4A1	ATP binding	Molecular function	-
SAT1	6303	spermidine/spermine N1-acetyltransferase 1	protein binding	Molecular function	16189514
SC5D	6309	sterol-C5-desaturase	lipid metabolic process	Biological process	8976377
TMPRSS15	5651	transmembrane protease, serine 15	brush border	Cellular component	8052624
MYRIP	25924	myosin VIIA and Rab interacting protein	synapse	Cellular component	-
TAF10	6881	TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa	chromatin organization	Biological process	-
GLRX3	10539	glutaredoxin 3	negative regulation of cardiac muscle hypertrophy	Biological process	-
PPARGC1B	133522	peroxisome proliferator-activated receptor gamma, coactivator 1 beta	bone trabecula formation	Biological process	-
KLRC2	3822	killer cell lectin-like receptor subfamily C, member 2	signal transduction	Biological process	2007850
REL	5966	v-rel avian reticuloendotheliosis viral oncogene homolog	cytosol	Cellular component	-
PHYKPL	85007	5-phosphohydroxy-L-lysine phospho-lyase	pyridoxal phosphate binding	Molecular function	-
FSBP	100861412	fibrinogen silencer binding protein	nucleus	Cellular component	20531236
REXO2	25996	RNA exonuclease 2	nucleotide metabolic process	Biological process	10851236
NUP153	9972	nucleoporin 153kDa	protein binding	Molecular function	11777942
FGF12	2257	fibroblast growth factor 12	synaptic transmission	Biological process	-
ITIH4	3700	inter-alpha-trypsin inhibitor heavy chain family, member 4	serine-type endopeptidase inhibitor activity	Molecular function	-
HOXB1	3211	homeobox B1	rhombomere 5 development	Biological process	-
ANGPTL3	27329	angiopoietin-like 3	enzyme inhibitor activity	Molecular function	-
MTF2	22823	metal response element binding transcription factor 2	cytoplasm	Cellular component	8619255
NCBP1	4686	nuclear cap binding protein subunit 1, 80kDa	cytosol	Cellular component	-
BCAP29	55973	B-cell receptor-associated protein 29	ER to Golgi vesicle-mediated transport	Biological process	-
LDHB	3945	lactate dehydrogenase B	protein binding	Molecular function	24725412
KCNAB3	9196	potassium channel, voltage gated subfamily A regulatory beta subunit 3	plasma membrane	Cellular component	-
LPP	4026	LIM domain containing preferred translocation partner in lipoma	biological_process	Biological process	-
IKBKB	3551	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	IkappaB kinase activity	Molecular function	18626576
PIK3C3	5289	phosphatidylinositol 3-kinase, catalytic subunit type 3	phospholipid metabolic process	Biological process	-
ATF5	22809	activating transcription factor 5	cytoplasm	Cellular component	-
ERGIC1	57222	endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1	endoplasmic reticulum membrane	Cellular component	-
SCP2	6342	sterol carrier protein 2	alpha-linolenic acid metabolic process	Biological process	-
NFATC3	4775	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	cytoplasm	Cellular component	-
AAAS	8086	achalasia, adrenocortical insufficiency, alacrimia	carbohydrate metabolic process	Biological process	-
PPP3CC	5533	protein phosphatase 3, catalytic subunit, gamma isozyme	cytosol	Cellular component	-
LRP6	4040	low density lipoprotein receptor-related protein 6	positive regulation of apoptotic process	Biological process	-
DNAJC3	5611	DnaJ (Hsp40) homolog, subfamily C, member 3	defense response to virus	Biological process	-
GRB2	2885	growth factor receptor-bound protein 2	cell-cell junction	Cellular component	-
NPC1L1	29881	NPC1-like 1	Rab GTPase binding	Molecular function	19542231
ANKLE2	23141	ankyrin repeat and LEM domain containing 2	mitotic nuclear division	Biological process	-
DRD2	1813	dopamine receptor D2	behavioral response to ethanol	Biological process	-
NSRP1	84081	nuclear speckle splicing regulatory protein 1	mRNA processing	Biological process	-
CACNA1S	779	calcium channel, voltage-dependent, L type, alpha 1S subunit	calcium ion transmembrane transport	Biological process	-
MDH1	4190	malate dehydrogenase 1, NAD (soluble)	NADH metabolic process	Biological process	-
SLC9A3R1	9368	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1	beta-2 adrenergic receptor binding	Molecular function	9560162
PPAPDC2	403313	phosphatidic acid phosphatase type 2 domain containing 2	metabolic process	Biological process	-
DACH2	117154	dachshund family transcription factor 2	development of primary female sexual characteristics	Biological process	-
RAB14	51552	RAB14, member RAS oncogene family	phagocytic vesicle membrane	Cellular component	-
TMC4	147798	transmembrane channel-like 4	ion transport	Biological process	-
GOT1	2805	glutamic-oxaloacetic transaminase 1, soluble	L-methionine biosynthetic process from methylthioadenosine	Biological process	-
PHC1	1911	polyhomeotic homolog 1 (Drosophila)	PRC1 complex	Cellular component	12167701
ZNF668	79759	zinc finger protein 668	metal ion binding	Molecular function	-
HRAS	3265	Harvey rat sarcoma viral oncogene homolog	innate immune response	Biological process	-
APOC3	345	apolipoprotein C-III	negative regulation of cholesterol import	Biological process	15778093
HSD17B6	8630	hydroxysteroid (17-beta) dehydrogenase 6	androgen biosynthetic process	Biological process	9188497
ATG10	83734	autophagy related 10	Atg12 transferase activity	Molecular function	20723759
IGSF6	10261	immunoglobulin superfamily, member 6	transmembrane signaling receptor activity	Molecular function	9809579
CASP8	841	caspase 8, apoptosis-related cysteine peptidase	proteolysis involved in cellular protein catabolic process	Biological process	10521396
WAC	51322	WW domain containing adaptor with coiled-coil	nucleus	Cellular component	22354037
PRKAB2	5565	protein kinase, AMP-activated, beta 2 non-catalytic subunit	insulin receptor signaling pathway	Biological process	-
SULF2	55959	sulfatase 2	bone development	Biological process	-
ZCCHC8	55596	zinc finger, CCHC domain containing 8	zinc ion binding	Molecular function	-
ARRB1	408	arrestin, beta 1	protein ubiquitination	Biological process	15878855
VEGFC	7424	vascular endothelial growth factor C	substrate-dependent cell migration	Biological process	8617204
ARF1	375	ADP-ribosylation factor 1	dendritic spine organization	Biological process	-
DERL1	79139	derlin 1	ER-associated misfolded protein catabolic process	Biological process	24089527
MYH1	4619	myosin, heavy chain 1, skeletal muscle, adult	protein binding	Molecular function	25416956
IL11RA	3590	interleukin 11 receptor, alpha	cytokine receptor activity	Molecular function	-
SNAP91	9892	synaptosomal-associated protein, 91kDa	protein binding	Molecular function	17762867
PRTFDC1	56952	phosphoribosyl transferase domain containing 1	guanine salvage	Biological process	21054786
CDH13	1012	cadherin 13	positive regulation of cell migration	Biological process	14729458
BST1	683	bone marrow stromal cell antigen 1	anchored component of membrane	Cellular component	-
SIK1	150094	salt-inducible kinase 1	entrainment of circadian clock by photoperiod	Biological process	-
PDGFB	5155	platelet-derived growth factor beta polypeptide	monocyte chemotaxis	Biological process	17991872
PIP4K2B	8396	phosphatidylinositol-5-phosphate 4-kinase, type II, beta	nucleoplasm	Cellular component	-
EIF3A	8661	eukaryotic translation initiation factor 3, subunit A	formation of cytoplasmic translation initiation complex	Biological process	17581632
PRKAG1	5571	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	signal transduction	Biological process	2342480
BRMS1	25855	breast cancer metastasis suppressor 1	nucleus	Cellular component	17000776
SREK1IP1	285672	SREK1-interacting protein 1	RNA splicing	Biological process	-
EIF2B1	1967	eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa	positive regulation of GTPase activity	Biological process	11323413
CYFIP2	26999	cytoplasmic FMR1 interacting protein 2	synapse	Cellular component	11438699
VRK2	7444	vaccinia related kinase 2	protein autophosphorylation	Biological process	14645249
SPHKAP	80309	SPHK1 interactor, AKAP domain containing	protein kinase A binding	Molecular function	20394097
AXL	558	AXL receptor tyrosine kinase	negative regulation of tumor necrosis factor production	Biological process	-
OR8B12	219858	olfactory receptor, family 8, subfamily B, member 12	odorant binding	Molecular function	-
PCSK5	5125	proprotein convertase subtilisin/kexin type 5	peptide hormone processing	Biological process	8901832
SRY	6736	sex determining region Y	nuclear speck	Cellular component	-
CACFD1	11094	calcium channel flower domain containing 1	plasma membrane	Cellular component	-
IL6	3569	interleukin 6	positive regulation of neuron differentiation	Biological process	-
RAB21	23011	RAB21, member RAS oncogene family	positive regulation of receptor-mediated endocytosis	Biological process	15561770
MCPH1	79648	microcephalin 1	cytoplasm	Cellular component	-
PLA2G4B	100137049	phospholipase A2, group IVB (cytosolic)	phosphatidylglycerol acyl-chain remodeling	Biological process	-
YAF2	10138	YY1 associated factor 2	negative regulation of transcription, DNA-templated	Biological process	12706874
CR1	1378	complement component (3b/4b) receptor 1 (Knops blood group)	negative regulation of complement activation, classical pathway	Biological process	10531307
MGST2	4258	microsomal glutathione S-transferase 2	plasma membrane	Cellular component	9092565
MTMR3	8897	myotubularin related protein 3	protein dephosphorylation	Biological process	10733931
RPS4Y1	6192	ribosomal protein S4, Y-linked 1	structural constituent of ribosome	Molecular function	8358435
ADCY9	115	adenylate cyclase 9	neurotrophin TRK receptor signaling pathway	Biological process	-
SLC18A3	6572	solute carrier family 18 (vesicular acetylcholine transporter), member 3	membrane	Cellular component	8071310
NDFIP2	54602	Nedd4 family interacting protein 2	protein binding	Molecular function	18776082
CAV3	859	caveolin 3	Z disc	Cellular component	-
SRSF5	6430	serine/arginine-rich splicing factor 5	nucleoplasm	Cellular component	-
RBMY1F	159163	RNA binding motif protein, Y-linked, family 1, member F	cellular_component	Cellular component	-
P2RX6	9127	purinergic receptor P2X, ligand gated ion channel, 6	ATP binding	Molecular function	12088286
PHC2	1912	polyhomeotic homolog 2 (Drosophila)	heterochromatin	Cellular component	-
PIGB	9488	phosphatidylinositol glycan anchor biosynthesis, class B	GPI anchor biosynthetic process	Biological process	8861954
PIK3CA	5290	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	protein serine/threonine kinase activity	Molecular function	-
RAB35	11021	RAB35, member RAS oncogene family	GDP binding	Molecular function	20937701
ARHGAP35	2909	Rho GTPase activating protein 35	small GTPase mediated signal transduction	Biological process	-
PDGFB	5155	platelet-derived growth factor beta polypeptide	platelet alpha granule lumen	Cellular component	-
CR2	1380	complement component (3d/Epstein Barr virus) receptor 2	immune response	Biological process	2827171
RBM19	9904	RNA binding motif protein 19	positive regulation of embryonic development	Biological process	-
GNRH1	2796	gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)	gonadotropin hormone-releasing hormone activity	Molecular function	-
TCF3	6929	transcription factor 3	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	14576336
PDE8A	5151	phosphodiesterase 8A	signal transducer activity	Molecular function	-
DCDC2	51473	doublecortin domain containing 2	cellular defense response	Biological process	10601354
IQSEC3	440073	IQ motif and Sec7 domain 3	ARF guanyl-nucleotide exchange factor activity	Molecular function	-
DAB1	1600	Dab, reelin signal transducer, homolog 1 (Drosophila)	negative regulation of cell adhesion	Biological process	-
ASIP	434	agouti signaling protein	hormone-mediated signaling pathway	Biological process	-
KCNAB2	8514	potassium channel, voltage gated subfamily A regulatory beta subunit 2	potassium ion transmembrane transport	Biological process	-
CDC40	51362	cell division cycle 40	spliceosomal complex	Cellular component	9524131
TMSB10	9168	thymosin beta 10	cytoplasm	Cellular component	-
DPP4	1803	dipeptidyl-peptidase 4	lamellipodium	Cellular component	16651416
CPEB2	132864	cytoplasmic polyadenylation element binding protein 2	ribosome binding	Molecular function	-
STX1A	6804	syntaxin 1A (brain)	synaptic vesicle	Cellular component	-
ZNF517	340385	zinc finger protein 517	regulation of transcription, DNA-templated	Biological process	-
TCF7	6932	transcription factor 7 (T-cell specific, HMG-box)	transcription factor complex	Cellular component	-
LRRC37A3	374819	leucine rich repeat containing 37, member A3	integral component of membrane	Cellular component	-
TRIM25	7706	tripartite motif containing 25	translesion synthesis	Biological process	-
LGR4	55366	leucine-rich repeat containing G protein-coupled receptor 4	G-protein coupled receptor signaling pathway	Biological process	-
SYT1	6857	synaptotagmin I	phosphatidylinositol-4,5-bisphosphate binding	Molecular function	-
SF1	7536	splicing factor 1	regulation of steroid biosynthetic process	Biological process	-
RAB1A	5861	RAB1A, member RAS oncogene family	intracellular protein transport	Biological process	-
MYC	4609	v-myc avian myelocytomatosis viral oncogene homolog	DNA binding	Molecular function	10597290
MEN1	4221	multiple endocrine neoplasia I	four-way junction DNA binding	Molecular function	15331604
RNF2	6045	ring finger protein 2	RING-like zinc finger domain binding	Molecular function	16714294
OAS1	4938	2'-5'-oligoadenylate synthetase 1, 40/46kDa	2'-5'-oligoadenylate synthetase activity	Molecular function	11682059
TCF3	6929	transcription factor 3	response to lipopolysaccharide	Biological process	-
DMRT1	1761	doublesex and mab-3 related transcription factor 1	chromatin binding	Molecular function	-
SARS2	54938	seryl-tRNA synthetase 2, mitochondrial	serine-tRNA ligase activity	Molecular function	-
MMP8	4317	matrix metallopeptidase 8	extracellular matrix disassembly	Biological process	-
PPP1CB	5500	protein phosphatase 1, catalytic subunit, beta isozyme	entrainment of circadian clock by photoperiod	Biological process	-
SETD1A	9739	SET domain containing 1A	regulation of transcription, DNA-templated	Biological process	-
PSMC6	5706	proteasome (prosome, macropain) 26S subunit, ATPase, 6	proteasome-activating ATPase activity	Molecular function	-
OR2L5	81466	olfactory receptor, family 2, subfamily L, member 5	sensory perception of smell	Biological process	-
CALR	811	calreticulin	response to testosterone	Biological process	-
MAP1S	55201	microtubule-associated protein 1S	brain development	Biological process	15528209
FGFR2	2263	fibroblast growth factor receptor 2	positive regulation of smooth muscle cell proliferation	Biological process	-
PSMF1	9491	proteasome (prosome, macropain) inhibitor subunit 1 (PI31)	G1/S transition of mitotic cell cycle	Biological process	-
ITGAV	3685	integrin, alpha V	leukocyte migration	Biological process	-
CC2D2A	57545	coiled-coil and C2 domain containing 2A	ciliary transition zone	Cellular component	-
ABCC8	6833	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	signal transduction	Biological process	7502040
MAPRE2	10982	microtubule-associated protein, RP/EB family, member 2	mitotic nuclear division	Biological process	-
GREM1	26585	gremlin 1, DAN family BMP antagonist	signal transduction by p53 class mediator	Biological process	9660951
GAL3ST4	79690	galactose-3-O-sulfotransferase 4	proteoglycan biosynthetic process	Biological process	11333265
FXYD1	5348	FXYD domain containing ion transport regulator 1	regulation of heart contraction	Biological process	19683723
ELP3	55140	elongator acetyltransferase complex subunit 3	iron-sulfur cluster binding	Molecular function	-
PPAP2B	8613	phosphatidic acid phosphatase type 2B	phosphoprotein phosphatase activity	Molecular function	9705349
RPS27A	6233	ribosomal protein S27a	SRP-dependent cotranslational protein targeting to membrane	Biological process	-
KRT8	3856	keratin 8, type II	keratin filament	Cellular component	-
SLC26A8	116369	solute carrier family 26 (anion exchanger), member 8	plasma membrane	Cellular component	11278976
PARD6A	50855	par-6 family cell polarity regulator alpha	transforming growth factor beta receptor signaling pathway	Biological process	-
EGFR	1956	epidermal growth factor receptor	cellular response to dexamethasone stimulus	Biological process	-
FADD	8772	Fas (TNFRSF6)-associated via death domain	regulation of extrinsic apoptotic signaling pathway via death domain receptors	Biological process	-
PPARA	5465	peroxisome proliferator-activated receptor alpha	positive regulation of fatty acid beta-oxidation	Biological process	16271724
PIGZ	80235	phosphatidylinositol glycan anchor biosynthesis, class Z	alpha-1,2-mannosyltransferase activity	Molecular function	15208306
WRN	7486	Werner syndrome, RecQ helicase-like	G-quadruplex DNA binding	Molecular function	11433031
AP1M2	10053	adaptor-related protein complex 1, mu 2 subunit	regulation of defense response to virus by virus	Biological process	-
HLA-DOA	3111	major histocompatibility complex, class II, DO alpha	regulation of T cell differentiation	Biological process	-
MAP4K4	9448	mitogen-activated protein kinase kinase kinase kinase 4	ATP binding	Molecular function	9890973
LRSAM1	90678	leucine rich repeat and sterile alpha motif containing 1	membrane	Cellular component	15256501
NTNG2	84628	netrin G2	axonogenesis	Biological process	-
NFU1	27247	NFU1 iron-sulfur cluster scaffold	protein binding	Molecular function	11342215
ADAM17	6868	ADAM metallopeptidase domain 17	extracellular matrix organization	Biological process	-
MTOR	2475	mechanistic target of rapamycin (serine/threonine kinase)	regulation of myelination	Biological process	-
ARID2	196528	AT rich interactive domain 2 (ARID, RFX-like)	metal ion binding	Molecular function	-
CAMTA2	23125	calmodulin binding transcription activator 2	cardiac muscle hypertrophy in response to stress	Biological process	16678093
MIF	4282	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	positive regulation of lipopolysaccharide-mediated signaling pathway	Biological process	-
ZMYM3	9203	zinc finger, MYM-type 3	cytoskeleton organization	Biological process	21834987
ATF7IP2	80063	activating transcription factor 7 interacting protein 2	nucleolus	Cellular component	-
HMGB1	3146	high mobility group box 1	cytokine activity	Molecular function	-
ATP5O	539	ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit	ATPase activity	Molecular function	12110673
C5AR2	27202	complement component 5a receptor 2	positive regulation of epithelial cell proliferation	Biological process	-
DRG1	4733	developmentally regulated GTP binding protein 1	GTP binding	Molecular function	-
CAT	847	catalase	osteoblast differentiation	Biological process	16210410
OR5K4	403278	olfactory receptor, family 5, subfamily K, member 4	olfactory receptor activity	Molecular function	-
CSNK1G2	1455	casein kinase 1, gamma 2	positive regulation of canonical Wnt signaling pathway	Biological process	-
GPX2	2877	glutathione peroxidase 2	response to symbiotic bacterium	Biological process	-
HHAT	55733	hedgehog acyltransferase	multicellular organismal development	Biological process	-
ST5	6764	suppression of tumorigenicity 5	positive regulation of GTPase activity	Biological process	-
BRAF	673	B-Raf proto-oncogene, serine/threonine kinase	response to cAMP	Biological process	-
ALX1	8092	ALX homeobox 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	9753625
LRP6	4040	low density lipoprotein receptor-related protein 6	canonical Wnt signaling pathway	Biological process	18215320
FAM60A	58516	family with sequence similarity 60, member A	protein binding	Molecular function	23752268
RLBP1	6017	retinaldehyde binding protein 1	vitamin A metabolic process	Biological process	9326942
GADD45A	1647	growth arrest and DNA-damage-inducible, alpha	positive regulation of JNK cascade	Biological process	9827804
HMGB2	3148	high mobility group box 2	chromatin organization	Biological process	11909973
PTK2B	2185	protein tyrosine kinase 2 beta	positive regulation of cell-matrix adhesion	Biological process	18765415
OR2B11	127623	olfactory receptor, family 2, subfamily B, member 11	olfactory receptor activity	Molecular function	-
FKBP7	51661	FK506 binding protein 7	endoplasmic reticulum membrane	Cellular component	-
PEAK1	79834	pseudopodium-enriched atypical kinase 1	peptidyl-tyrosine phosphorylation	Biological process	-
NOL6	65083	nucleolar protein 6 (RNA-associated)	rRNA processing	Biological process	-
DDX49	54555	DEAD (Asp-Glu-Ala-Asp) box polypeptide 49	poly(A) RNA binding	Molecular function	22658674
SRC	6714	SRC proto-oncogene, non-receptor tyrosine kinase	regulation of cell cycle	Biological process	-
HTRA1	5654	HtrA serine peptidase 1	serine-type peptidase activity	Molecular function	-
KRT6A	3853	keratin 6A, type II	positive regulation of cell proliferation	Biological process	7543104
SLC35A2	7355	solute carrier family 35 (UDP-galactose transporter), member A2	Golgi apparatus	Cellular component	-
SPG21	51324	spastic paraplegia 21 (autosomal recessive, Mast syndrome)	CD4 receptor binding	Molecular function	11113139
PYCRL	65263	pyrroline-5-carboxylate reductase-like	pyrroline-5-carboxylate reductase activity	Molecular function	-
OXTR	5021	oxytocin receptor	positive regulation of synapse assembly	Biological process	-
SIRT1	23411	sirtuin 1	deacetylase activity	Molecular function	18203716
SLC12A4	6560	solute carrier family 12 (potassium/chloride transporter), member 4	membrane	Cellular component	8663127
AP3D1	8943	adaptor-related protein complex 3, delta 1 subunit	nucleoplasm	Cellular component	-
CCDC88A	55704	coiled-coil domain containing 88A	regulation of actin cytoskeleton organization	Biological process	16139227
APOC1	341	apolipoprotein C-I	negative regulation of lipid metabolic process	Biological process	182536
STK11	6794	serine/threonine kinase 11	TCR signalosome assembly	Biological process	-
INPP5D	3635	inositol polyphosphate-5-phosphatase, 145kDa	negative regulation of osteoclast differentiation	Biological process	-
NLRP10	338322	NLR family, pyrin domain containing 10	helper T cell enhancement of adaptive immune response	Biological process	-
ZNF777	27153	zinc finger protein 777	cellular_component	Cellular component	-
ETS2	2114	v-ets avian erythroblastosis virus E26 oncogene homolog 2	protein binding	Molecular function	11909962
YIPF5	81555	Yip1 domain family, member 5	vesicle-mediated transport	Biological process	-
CACNB3	784	calcium channel, voltage-dependent, beta 3 subunit	calcium ion transmembrane transport	Biological process	-
TAC1	6863	tachykinin, precursor 1	detection of abiotic stimulus	Biological process	9482938
GCK	2645	glucokinase (hexokinase 4)	cellular response to leptin stimulus	Biological process	-
MC1R	4157	melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)	negative regulation of tumor necrosis factor production	Biological process	10233018
MT2A	4502	metallothionein 2A	protein binding	Molecular function	12646258
LYPLAL1	127018	lysophospholipase-like 1	lysophospholipase activity	Molecular function	12706107
CCL19	6363	chemokine (C-C motif) ligand 19	positive regulation of protein kinase B signaling	Biological process	15059845
NPY	4852	neuropeptide Y	movement of cell or subcellular component	Biological process	10488139
PTPN3	5774	protein tyrosine phosphatase, non-receptor type 3	protein binding	Molecular function	10364224
CADM2	253559	cell adhesion molecule 2	neuronal cell body membrane	Cellular component	-
RPL23A	6147	ribosomal protein L23a	translation	Biological process	-
TGM3	7053	transglutaminase 3	protein-glutamine gamma-glutamyltransferase activity	Molecular function	12679341
BMPR2	659	bone morphogenetic protein receptor, type II (serine/threonine kinase)	positive regulation of endothelial cell proliferation	Biological process	17992660
SLC19A1	6573	solute carrier family 19 (folate transporter), member 1	folic acid metabolic process	Biological process	-
CLCA3P	9629	chloride channel accessory 3, pseudogene	calcium channel activity	Molecular function	-
POU2AF1	5450	POU class 2 associating factor 1	humoral immune response	Biological process	7859290
BIRC3	330	baculoviral IAP repeat containing 3	negative regulation of apoptotic process	Biological process	8552191
DPM3	54344	dolichyl-phosphate mannosyltransferase polypeptide 3	carbohydrate metabolic process	Biological process	10835346
SLURP1	57152	secreted LY6/PLAUR domain containing 1	extracellular region	Cellular component	14721776
INCENP	3619	inner centromere protein antigens 135/155kDa	protein complex	Cellular component	16239925
CRLS1	54675	cardiolipin synthase 1	glycerophospholipid biosynthetic process	Biological process	-
ACHE	43	acetylcholinesterase (Yt blood group)	extracellular space	Cellular component	-
AGXT2	64902	alanine--glyoxylate aminotransferase 2	mitochondrion	Cellular component	20018850
TGFB2	7042	transforming growth factor, beta 2	extracellular matrix organization	Biological process	-
IL1A	3552	interleukin 1, alpha	positive regulation of JNK cascade	Biological process	-
NOS2	4843	nitric oxide synthase 2, inducible	cytosol	Cellular component	-
UVRAG	7405	UV radiation resistance associated	phagocytic vesicle	Cellular component	-
DACH1	1602	dachshund family transcription factor 1	negative regulation of DNA biosynthetic process	Biological process	16980615
DRD4	1815	dopamine receptor D4	SH3 domain binding	Molecular function	9843378
GHRL	51738	ghrelin/obestatin prepropeptide	cartilage development	Biological process	15576457
NUP133	55746	nucleoporin 133kDa	transmembrane transport	Biological process	-
MT1B	4490	metallothionein 1B	perinuclear region of cytoplasm	Cellular component	-
IL6	3569	interleukin 6	response to amino acid	Biological process	-
TLN2	83660	talin 2	structural constituent of cytoskeleton	Molecular function	-
HOXD11	3237	homeobox D11	sequence-specific DNA binding	Molecular function	-
HVCN1	84329	hydrogen voltage gated channel 1	regulation of ion transmembrane transport	Biological process	-
KMT2A	4297	lysine (K)-specific methyltransferase 2A	positive regulation of transcription from RNA polymerase II promoter	Biological process	20861184
SLC6A2	6530	solute carrier family 6 (neurotransmitter transporter), member 2	protein binding	Molecular function	11343649
NMU	10874	neuromedin U	neuropeptide signaling pathway	Biological process	-
GMDS	2762	GDP-mannose 4,6-dehydratase	extracellular exosome	Cellular component	19199708
MEP1B	4225	meprin A, beta	plasma membrane	Cellular component	9288916
CSF1	1435	colony stimulating factor 1 (macrophage)	positive regulation of macrophage differentiation	Biological process	2460758
TP53INP2	58476	tumor protein p53 inducible nuclear protein 2	protein binding	Molecular function	19056683
BABAM1	29086	BRISC and BRCA1 A complex member 1	BRISC complex	Cellular component	19214193
TREM1	54210	triggering receptor expressed on myeloid cells 1	positive regulation of defense response to virus by host	Biological process	22020285
IL34	146433	interleukin 34	innate immune response	Biological process	-
EEA1	8411	early endosome antigen 1	cytoplasm	Cellular component	7768953
SLC6A9	6536	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	neurotransmitter transport	Biological process	-
NUP62CL	54830	nucleoporin 62kDa C-terminal like	structural constituent of nuclear pore	Molecular function	-
OR6K3	391114	olfactory receptor, family 6, subfamily K, member 3	G-protein coupled receptor signaling pathway	Biological process	-
SPIN2A	54466	spindlin family, member 2A	regulation of cell cycle	Biological process	-
FLNA	2316	filamin A, alpha	platelet degranulation	Biological process	-
XRCC5	7520	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	poly(A) RNA binding	Molecular function	22658674
ZMYM1	79830	zinc finger, MYM-type 1	zinc ion binding	Molecular function	-
CDH17	1015	cadherin 17, LI cadherin (liver-intestine)	integral component of membrane	Cellular component	-
CASKIN1	57524	CASK interacting protein 1	signal transduction	Biological process	12040031
LRAT	9227	lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)	visual perception	Biological process	-
ZDHHC7	55625	zinc finger, DHHC-type containing 7	protein-cysteine S-palmitoyltransferase activity	Molecular function	-
IGSF11	152404	immunoglobulin superfamily, member 11	regulation of growth	Biological process	-
NEUROG3	50674	neurogenin 3	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
CAPZB	832	capping protein (actin filament) muscle Z-line, beta	barbed-end actin filament capping	Biological process	-
SLC34A2	10568	solute carrier family 34 (type II sodium/phosphate cotransporter), member 2	phosphate ion binding	Molecular function	12488042
SLC9A1	6548	solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1	hydrogen ion transmembrane transport	Biological process	24840010
KCNMB2	10242	potassium channel subfamily M regulatory beta subunit 2	plasma membrane	Cellular component	-
MACROD1	28992	MACRO domain containing 1	cellular response to DNA damage stimulus	Biological process	23474712
MBOAT2	129642	membrane bound O-acyltransferase domain containing 2	1-acylglycerol-3-phosphate O-acyltransferase activity	Molecular function	-
PCDH15	65217	protocadherin-related 15	extracellular space	Cellular component	16369489
PTTG1	9232	pituitary tumor-transforming 1	cell division	Biological process	-
CDC42	998	cell division cycle 42	spindle midzone	Cellular component	15642749
TLK1	9874	tousled-like kinase 1	intracellular protein transport	Biological process	10588641
POR	5447	P450 (cytochrome) oxidoreductase	nitrate catabolic process	Biological process	-
IWS1	55677	IWS1 homolog (S. cerevisiae)	nucleus	Cellular component	17234882
ITGA2	3673	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	integrin binding	Molecular function	-
CASP3	836	caspase 3, apoptosis-related cysteine peptidase	erythrocyte differentiation	Biological process	18309324
NUP62	23636	nucleoporin 62kDa	negative regulation of epidermal growth factor receptor signaling pathway	Biological process	-
STEAP4	79689	STEAP family member 4	plasma membrane	Cellular component	-
FBXO44	93611	F-box protein 44	SCF ubiquitin ligase complex	Cellular component	18203720
ARHGEF3	50650	Rho guanine nucleotide exchange factor (GEF) 3	Rho guanyl-nucleotide exchange factor activity	Molecular function	-
IFT74	80173	intraflagellar transport 74	intraciliary transport involved in cilium morphogenesis	Biological process	23990561
COL3A1	1281	collagen, type III, alpha 1	integrin-mediated signaling pathway	Biological process	14970208
FERMT2	10979	fermitin family member 2	integrin-mediated signaling pathway	Biological process	21325030
MLIP	90523	muscular LMNA-interacting protein	nuclear lumen	Cellular component	-
TAOK3	51347	TAO kinase 3	MAP kinase kinase kinase activity	Molecular function	-
IGKV2-40	28916	immunoglobulin kappa variable 2-40	extracellular exosome	Cellular component	23533145
PTPRK	5796	protein tyrosine phosphatase, receptor type, K	protein binding	Molecular function	15899872
PRKCD	5580	protein kinase C, delta	positive regulation of apoptotic signaling pathway	Biological process	-
RAB27A	5873	RAB27A, member RAS oncogene family	multivesicular body organization	Biological process	23092844
SPAG11A	653423	sperm associated antigen 11A	extracellular region	Cellular component	-
APEX1	328	APEX nuclease (multifunctional DNA repair enzyme) 1	uracil DNA N-glycosylase activity	Molecular function	10805771
PIK3CA	5290	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	insulin receptor signaling pathway	Biological process	-
CITED1	4435	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1	spongiotrophoblast layer development	Biological process	-
RRP15	51018	ribosomal RNA processing 15 homolog (S. cerevisiae)	nucleus	Cellular component	-
RANBP2	5903	RAN binding protein 2	nuclear pore nuclear basket	Cellular component	11839768
GPRC5B	51704	G protein-coupled receptor, class C, group 5, member B	positive regulation of neuron projection development	Biological process	-
SMARCA2	6595	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	negative regulation of transcription from RNA polymerase II promoter	Biological process	17938176
EDN3	1908	endothelin 3	blood circulation	Biological process	8298278
IL6	3569	interleukin 6	negative regulation of hormone secretion	Biological process	-
SEMA4C	54910	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C	muscle cell differentiation	Biological process	17498836
DIS3L	115752	DIS3 like exosome 3'-5' exoribonuclease	rRNA catabolic process	Biological process	20368444
PSMB6	5694	proteasome (prosome, macropain) subunit, beta type, 6	negative regulation of canonical Wnt signaling pathway	Biological process	-
LILRB1	10859	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	immune response-inhibiting cell surface receptor signaling pathway	Biological process	18550825
OCA2	4948	oculocutaneous albinism II	transmembrane transport	Biological process	-
CETN2	1069	centrin, EF-hand protein, 2	heterotrimeric G-protein binding	Molecular function	-
THBS1	7057	thrombospondin 1	extracellular matrix	Cellular component	9304800
NOP58	51602	NOP58 ribonucleoprotein	membrane	Cellular component	19946888
PLAG1	5324	pleiomorphic adenoma gene 1	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	10646861
JADE2	23338	jade family PHD finger 2	histone H4-K16 acetylation	Biological process	16387653
SMARCA4	6597	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	nucleosome disassembly	Biological process	8895581
PDE5A	8654	phosphodiesterase 5A, cGMP-specific	negative regulation of T cell proliferation	Biological process	-
PITPNB	23760	phosphatidylinositol transfer protein, beta	glycerophospholipid biosynthetic process	Biological process	-
SEPP1	6414	selenoprotein P, plasma, 1	growth	Biological process	-
MEGF10	84466	multiple EGF-like-domains 10	muscle cell development	Biological process	22101682
KCNJ9	3765	potassium channel, inwardly rectifying subfamily J, member 9	G-protein activated inward rectifier potassium channel activity	Molecular function	-
OLA1	29789	Obg-like ATPase 1	centrosome	Cellular component	-
SMAD2	4087	SMAD family member 2	zygotic specification of dorsal/ventral axis	Biological process	9436979
FLI1	2313	Fli-1 proto-oncogene, ETS transcription factor	organ morphogenesis	Biological process	-
JAKMIP1	152789	janus kinase and microtubule interacting protein 1	kinesin binding	Molecular function	-
TNFSF13B	10673	tumor necrosis factor (ligand) superfamily, member 13b	B cell costimulation	Biological process	-
HTRA1	5654	HtrA serine peptidase 1	extracellular space	Cellular component	9852107
KMO	8564	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	kynurenine 3-monooxygenase activity	Molecular function	10672018
NLGN2	57555	neuroligin 2	positive regulation of insulin secretion	Biological process	22528485
DAO	1610	D-amino-acid oxidase	D-serine metabolic process	Biological process	21679769
TLR2	7097	toll-like receptor 2	positive regulation of chemokine production	Biological process	19740627
SERPINE1	5054	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	angiogenesis	Biological process	11866539
ZNF488	118738	zinc finger protein 488	sequence-specific DNA binding RNA polymerase II transcription factor activity	Molecular function	-
NCR3	259197	natural cytotoxicity triggering receptor 3	inflammatory response	Biological process	10941844
HMGXB4	10042	HMG box domain containing 4	chromatin remodeling	Biological process	-
TOMM22	56993	translocase of outer mitochondrial membrane 22 homolog (yeast)	mitochondrion	Cellular component	-
SH3BP4	23677	SH3-domain binding protein 4	coated pit	Cellular component	-
RGS18	64407	regulator of G-protein signaling 18	termination of G-protein coupled receptor signaling pathway	Biological process	-
ATF2	1386	activating transcription factor 2	toll-like receptor 10 signaling pathway	Biological process	-
POT1	25913	protection of telomeres 1	negative regulation of telomere maintenance via telomerase	Biological process	15181449
ENPP1	5167	ectonucleotide pyrophosphatase/phosphodiesterase 1	calcium ion binding	Molecular function	-
MAP2K1	5604	mitogen-activated protein kinase kinase 1	positive regulation of gene expression	Biological process	15155804
LCAT	3931	lecithin-cholesterol acyltransferase	extracellular space	Cellular component	10559507
MRPL28	10573	mitochondrial ribosomal protein L28	protein binding	Molecular function	20601428
ADRB2	154	adrenoceptor beta 2, surface	response to cold	Biological process	-
RASGRP3	25780	RAS guanyl releasing protein 3 (calcium and DAG-regulated)	integral component of plasma membrane	Cellular component	10934204
SQSTM1	8878	sequestosome 1	protein binding	Molecular function	14676191
UHRF2	115426	ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase	regulation of methylation-dependent chromatin silencing	Biological process	-
NCOA5	57727	nuclear receptor coactivator 5	chromatin binding	Molecular function	-
MOCOS	55034	molybdenum cofactor sulfurase	pyridoxal phosphate binding	Molecular function	-
SLC4A1	6521	solute carrier family 4 (anion exchanger), member 1 (Diego blood group)	ion transport	Biological process	-
CGRRF1	10668	cell growth regulator with ring finger domain 1	response to stress	Biological process	8968090
SHROOM3	57619	shroom family member 3	cellular pigment accumulation	Biological process	-
SP4	6671	Sp4 transcription factor	microtubule cytoskeleton	Cellular component	-
ALDH3A1	218	aldehyde dehydrogenase 3 family, member A1	aging	Biological process	-
TAL1	6886	T-cell acute lymphocytic leukemia 1	positive regulation of erythrocyte differentiation	Biological process	-
FAM21C	253725	family with sequence similarity 21, member C	early endosome	Cellular component	19922874
TG	7038	thyroglobulin	extracellular region	Cellular component	14718574
NR2E1	7101	nuclear receptor subfamily 2, group E, member 1	aggressive behavior	Biological process	-
SDCCAG8	10806	serologically defined colon cancer antigen 8	G2/M transition of mitotic cell cycle	Biological process	-
CNOT6L	246175	CCR4-NOT transcription complex, subunit 6-like	nuclear-transcribed mRNA poly(A) tail shortening	Biological process	-
PMS2	5395	PMS2 postmeiotic segregation increased 2 (S. cerevisiae)	single base insertion or deletion binding	Molecular function	10871409
HES5	388585	hes family bHLH transcription factor 5	negative regulation of neuron differentiation	Biological process	-
THBS1	7057	thrombospondin 1	response to glucose	Biological process	18096704
POLA1	5422	polymerase (DNA directed), alpha 1, catalytic subunit	leading strand elongation	Biological process	2175912
GPLD1	2822	glycosylphosphatidylinositol specific phospholipase D1	extracellular space	Cellular component	15907827
HRH2	3274	histamine receptor H2	histamine-induced gastric acid secretion	Biological process	-
HDLBP	3069	high density lipoprotein binding protein	poly(A) RNA binding	Molecular function	22658674
NRM	11270	nurim (nuclear envelope membrane protein)	molecular_function	Molecular function	-
HSPA1L	3305	heat shock 70kDa protein 1-like	response to unfolded protein	Biological process	9685725
TGFBR1	7046	transforming growth factor, beta receptor 1	transforming growth factor beta receptor activity, type I	Molecular function	-
APOD	347	apolipoprotein D	negative regulation of smooth muscle cell proliferation	Biological process	14551159
FOXP3	50943	forkhead box P3	negative regulation of interleukin-17 production	Biological process	18368049
PYCARD	29108	PYD and CARD domain containing	positive regulation of antigen processing and presentation of peptide antigen via MHC class II	Biological process	-
NR3C2	4306	nuclear receptor subfamily 3, group C, member 2	sequence-specific DNA binding transcription factor activity	Molecular function	-
SLC17A6	57084	solute carrier family 17 (vesicular glutamate transporter), member 6	integral component of membrane	Cellular component	-
CAV1	857	caveolin 1, caveolae protein, 22kDa	nitric-oxide synthase binding	Molecular function	12852865
SPECC1L	23384	sperm antigen with calponin homology and coiled-coil domains 1-like	spindle	Cellular component	-
SUMO3	6612	small ubiquitin-like modifier 3	SUMO transferase activity	Molecular function	-
UPP1	7378	uridine phosphorylase 1	pyrimidine nucleoside salvage	Biological process	-
LRP1	4035	low density lipoprotein receptor-related protein 1	negative regulation of neuron apoptotic process	Biological process	-
KHDRBS3	10656	KH domain containing, RNA binding, signal transduction associated 3	nucleus	Cellular component	10332027
PKD2	5311	polycystic kidney disease 2 (autosomal dominant)	extracellular exosome	Cellular component	19056867
SH3GL2	6456	SH3-domain GRB2-like 2	negative regulation of epidermal growth factor receptor signaling pathway	Biological process	-
F11	2160	coagulation factor XI	plasma membrane	Cellular component	-
OR11L1	391189	olfactory receptor, family 11, subfamily L, member 1	plasma membrane	Cellular component	-
SDCBP	6386	syndecan binding protein (syntenin)	positive regulation of phosphorylation	Biological process	18256285
LGALS16	148003	lectin, galactoside-binding, soluble, 16	lactose binding	Molecular function	19497882
HEATR1	55127	HEAT repeat containing 1	poly(A) RNA binding	Molecular function	22658674
TGIF2	60436	TGFB-induced factor homeobox 2	nucleus	Cellular component	11006116
FLNA	2316	filamin A, alpha	trans-Golgi network	Cellular component	-
MFF	56947	mitochondrial fission factor	positive regulation of release of cytochrome c from mitochondria	Biological process	21149567
TH	7054	tyrosine hydroxylase	cellular response to nicotine	Biological process	-
CYP4Z1	199974	cytochrome P450, family 4, subfamily Z, polypeptide 1	heme binding	Molecular function	-
SLC41A1	254428	solute carrier family 41 (magnesium transporter), member 1	transmembrane transport	Biological process	-
MBNL2	10150	muscleblind-like splicing regulator 2	poly(A) RNA binding	Molecular function	22658674
FOXN3	1112	forkhead box N3	negative regulation of transcription, DNA-templated	Biological process	16102918
MME	4311	membrane metallo-endopeptidase	endopeptidase activity	Molecular function	2531377
PHF5A	84844	PHD finger protein 5A	U2 snRNP	Cellular component	12234937
MYBPH	4608	myosin binding protein H	cell adhesion	Biological process	-
PSMC6	5706	proteasome (prosome, macropain) 26S subunit, ATPase, 6	cytosolic proteasome complex	Cellular component	-
MYO1B	4430	myosin IB	actin filament	Cellular component	16219689
TFIP11	24144	tuftelin interacting protein 11	catalytic step 2 spliceosome	Cellular component	11991638
SYCP2	10388	synaptonemal complex protein 2	male meiosis	Biological process	-
BCL2L2	599	BCL2-like 2	intrinsic apoptotic signaling pathway in response to DNA damage	Biological process	-
EIF2S1	1965	eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa	translational initiation	Biological process	-
FOXF1	2294	forkhead box F1	sequence-specific DNA binding	Molecular function	7957066
LPCAT1	79888	lysophosphatidylcholine acyltransferase 1	Golgi apparatus	Cellular component	-
HSPA2	3306	heat shock 70kDa protein 2	extracellular exosome	Cellular component	19056867
ARHGEF11	9826	Rho guanine nucleotide exchange factor (GEF) 11	positive regulation of apoptotic process	Biological process	-
C19orf68	374920	chromosome 19 open reading frame 68	protein binding	Molecular function	20195357
IL36G	56300	interleukin 36, gamma	positive regulation of interleukin-6 production	Biological process	-
KRT20	54474	keratin 20, type I	cytoplasm	Cellular component	10973561
DDOST	1650	dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)	oligosaccharyltransferase complex	Cellular component	15835887
CLOCK	9575	clock circadian regulator	chromatin DNA binding	Molecular function	-
ZNF672	79894	zinc finger protein 672	transcription, DNA-templated	Biological process	-
FGFR3	2261	fibroblast growth factor receptor 3	positive regulation of ERK1 and ERK2 cascade	Biological process	11294897
ITPR1	3708	inositol 1,4,5-trisphosphate receptor, type 1	vascular endothelial growth factor receptor signaling pathway	Biological process	-
LGR4	55366	leucine-rich repeat containing G protein-coupled receptor 4	osteoblast differentiation	Biological process	-
PLXNA4	91584	plexin A4	semaphorin-plexin signaling pathway	Biological process	19909241
EIF3G	8666	eukaryotic translation initiation factor 3, subunit G	nucleotide binding	Molecular function	-
CBWD3	445571	COBW domain containing 3	ATP binding	Molecular function	-
CAMK1	8536	calcium/calmodulin-dependent protein kinase I	nucleocytoplasmic transport	Biological process	-
IL27RA	9466	interleukin 27 receptor, alpha	cell surface receptor signaling pathway	Biological process	9600072
CEND1	51286	cell cycle exit and neuronal differentiation 1	integral component of membrane	Cellular component	-
FGF9	2254	fibroblast growth factor 9	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
STRADB	55437	STE20-related kinase adaptor beta	nucleus	Cellular component	14517248
HDC	3067	histidine decarboxylase	histidine decarboxylase activity	Molecular function	-
ITPR2	3709	inositol 1,4,5-trisphosphate receptor, type 2	blood coagulation	Biological process	-
ANXA2	302	annexin A2	calcium ion binding	Molecular function	-
ZNF257	113835	zinc finger protein 257	transcription, DNA-templated	Biological process	-
KIR2DL2	3803	killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2	integral component of membrane	Cellular component	-
MAP2K1	5604	mitogen-activated protein kinase kinase 1	regulation of vascular smooth muscle contraction	Biological process	-
HYAL1	3373	hyaluronoglucosaminidase 1	positive regulation of epithelial cell proliferation	Biological process	21829529
BCL2L11	10018	BCL2-like 11 (apoptosis facilitator)	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	-
AGAP2	116986	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	mitochondrion	Cellular component	-
AJUBA	84962	ajuba LIM protein	positive regulation of protein complex assembly	Biological process	15870274
DGKZ	8525	diacylglycerol kinase, zeta	protein kinase C-activating G-protein coupled receptor signaling pathway	Biological process	-
SLC39A14	23516	solute carrier family 39 (zinc transporter), member 14	endoplasmic reticulum	Cellular component	-
SLU7	10569	SLU7 splicing factor homolog (S. cerevisiae)	cytoplasm	Cellular component	-
PLA2R1	22925	phospholipase A2 receptor 1, 180kDa	plasma membrane	Cellular component	12225974
ZNF141	7700	zinc finger protein 141	limb morphogenesis	Biological process	23160277
ETV1	2115	ets variant 1	transcription from RNA polymerase II promoter	Biological process	7700648
APOB	338	apolipoprotein B	artery morphogenesis	Biological process	-
KSR1	8844	kinase suppressor of ras 1	Ras protein signal transduction	Biological process	8521512
DAPK3	1613	death-associated protein kinase 3	regulation of transcription, DNA-templated	Biological process	-
KCNJ11	3767	potassium channel, inwardly rectifying subfamily J, member 11	regulation of insulin secretion	Biological process	-
PAPSS2	9060	3'-phosphoadenosine 5'-phosphosulfate synthase 2	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process	Biological process	-
GSTM1	2944	glutathione S-transferase mu 1	enzyme binding	Molecular function	8373352
TBCD	6904	tubulin folding cofactor D	beta-tubulin binding	Molecular function	10831612
B9D1	27077	B9 protein domain 1	vasculature development	Biological process	-
CLDN18	51208	claudin 18	plasma membrane	Cellular component	-
MASP1	5648	mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)	complement activation, lectin pathway	Biological process	-
DDX3X	1654	DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked	eukaryotic initiation factor 4E binding	Molecular function	17667941
DPEP1	1800	dipeptidase 1 (renal)	negative regulation of cell migration	Biological process	20824289
LILRB2	10288	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	protein phosphatase 1 binding	Molecular function	9842885
PARVB	29780	parvin, beta	protein binding	Molecular function	18325335
SSTR5	6755	somatostatin receptor 5	regulation of insulin secretion	Biological process	-
MED8	112950	mediator complex subunit 8	RNA polymerase II transcription cofactor activity	Molecular function	-
BMPR1B	658	bone morphogenetic protein receptor, type IB	protein binding	Molecular function	11266516
MAPKAPK5	8550	mitogen-activated protein kinase-activated protein kinase 5	peptidyl-serine phosphorylation	Biological process	-
SFRP1	6422	secreted frizzled-related protein 1	cytosol	Cellular component	14581477
THTPA	79178	thiamine triphosphatase	vitamin metabolic process	Biological process	-
KCNK10	54207	potassium channel, two pore domain subfamily K, member 10	transport	Biological process	10880510
MZB1	51237	marginal zone B and B1 cell-specific protein	integrin activation	Biological process	-
AZIN2	113451	antizyme inhibitor 2	perikaryon	Cellular component	19832840
NGFR	4804	nerve growth factor receptor	regulation of glucose import in response to insulin stimulus	Biological process	-
MFNG	4242	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	metabolic process	Biological process	-
SNX33	257364	sorting nexin 33	endosomal transport	Biological process	22718350
MYO5B	4645	myosin VB	protein complex	Cellular component	17462998
PID1	55022	phosphotyrosine interaction domain containing 1	fat cell differentiation	Biological process	16815647
PIP5KL1	138429	phosphatidylinositol-4-phosphate 5-kinase-like 1	1-phosphatidylinositol-4-phosphate 5-kinase activity	Molecular function	-
PMCH	5367	pro-melanin-concentrating hormone	nucleus	Cellular component	-
TENM1	10178	teneurin transmembrane protein 1	nuclear matrix	Cellular component	-
ERVH48-1	90625	endogenous retrovirus group 48, member 1	extracellular space	Cellular component	23492904
ZNHIT1	10467	zinc finger, HIT-type containing 1	negative regulation of G0 to G1 transition	Biological process	-
MRPL46	26589	mitochondrial ribosomal protein L46	mitochondrial translational elongation	Biological process	-
CTSA	5476	cathepsin A	small molecule metabolic process	Biological process	-
NCOA5	57727	nuclear receptor coactivator 5	transcription, DNA-templated	Biological process	-
TGFB3	7043	transforming growth factor, beta 3	positive regulation of SMAD protein import into nucleus	Biological process	-
NFIB	4781	nuclear factor I/B	nucleolus	Cellular component	-
POU1F1	5449	POU class 1 homeobox 1	negative regulation of cell proliferation	Biological process	9392392
ATG4B	23192	autophagy related 4B, cysteine peptidase	protein binding	Molecular function	15187094
RIPK1	8737	receptor (TNFRSF)-interacting serine-threonine kinase 1	programmed cell death	Biological process	-
ZNF707	286075	zinc finger protein 707	DNA binding	Molecular function	-
PSEN2	5664	presenilin 2	positive regulation of catalytic activity	Biological process	15274632
ZNF483	158399	zinc finger protein 483	regulation of transcription, DNA-templated	Biological process	-
MOXD1	26002	monooxygenase, DBH-like 1	endoplasmic reticulum membrane	Cellular component	15337741
SRSF11	9295	serine/arginine-rich splicing factor 11	mRNA 3'-end processing	Biological process	-
CYP17A1	1586	cytochrome P450, family 17, subfamily A, polypeptide 1	oxidation-reduction process	Biological process	-
ACOXL	55289	acyl-CoA oxidase-like	peroxisome	Cellular component	-
CPA3	1359	carboxypeptidase A3 (mast cell)	cellular protein metabolic process	Biological process	-
ALDH18A1	5832	aldehyde dehydrogenase 18 family, member A1	protein binding	Molecular function	25416956
HEYL	26508	hes-related family bHLH transcription factor with YRPW motif-like	Notch signaling pathway	Biological process	-
CYP2C8	1558	cytochrome P450, family 2, subfamily C, polypeptide 8	caffeine oxidase activity	Molecular function	18619574
ERAP1	51752	endoplasmic reticulum aminopeptidase 1	interleukin-6 receptor binding	Molecular function	12748171
LGALS12	85329	lectin, galactoside-binding, soluble, 12	nucleus	Cellular component	-
IRF3	3661	interferon regulatory factor 3	toll-like receptor signaling pathway	Biological process	-
CUL3	8452	cullin 3	membrane	Cellular component	19946888
SLAMF9	89886	SLAM family member 9	receptor activity	Molecular function	-
MTG2	26164	mitochondrial ribosome-associated GTPase 2	mitochondrial inner membrane	Cellular component	23396448
HIP1R	9026	huntingtin interacting protein 1 related	clathrin-coated vesicle	Cellular component	11889126
AIMP1	9255	aminoacyl tRNA synthetase complex-interacting multifunctional protein 1	protein homodimerization activity	Molecular function	11306575
RAMP2	10266	receptor (G protein-coupled) activity modifying protein 2	response to estradiol	Biological process	-
TMED9	54732	transmembrane emp24 protein transport domain containing 9	endoplasmic reticulum-Golgi intermediate compartment	Cellular component	12237308
RPL38	6169	ribosomal protein L38	SRP-dependent cotranslational protein targeting to membrane	Biological process	-
NYAP2	57624	neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2	intracellular	Cellular component	-
CWH43	80157	cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)	GPI anchor biosynthetic process	Biological process	-
RAB1B	81876	RAB1B, member RAS oncogene family	virion assembly	Biological process	21680502
PXT1	222659	peroxisomal, testis specific 1	peroxisome	Cellular component	18160785
MYO1A	4640	myosin IA	myosin complex	Cellular component	-
KMO	8564	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	tryptophan catabolic process to kynurenine	Biological process	-
ZFYVE21	79038	zinc finger, FYVE domain containing 21	endosome	Cellular component	-
AKR7L	246181	aldo-keto reductase family 7-like (gene/pseudogene)	cytosol	Cellular component	-
CD3E	916	CD3e molecule, epsilon (CD3-TCR complex)	positive regulation of interleukin-2 biosynthetic process	Biological process	-
ARSB	411	arylsulfatase B	response to pH	Biological process	-
GDF5	8200	growth differentiation factor 5	identical protein binding	Molecular function	25174448
REXO1	57455	REX1, RNA exonuclease 1 homolog (S. cerevisiae)	exonuclease activity	Molecular function	-
UBE4B	10277	ubiquitination factor E4B	ligase activity	Molecular function	-
SUGCT	79783	succinyl-CoA:glutarate-CoA transferase	metabolic process	Biological process	-
KDR	3791	kinase insert domain receptor	calcium-mediated signaling using intracellular calcium source	Biological process	15215251
PHF21A	51317	PHD finger protein 21A	chromatin binding	Molecular function	-
MTUS1	57509	microtubule associated tumor suppressor 1	spindle	Cellular component	-
FLOT2	2319	flotillin 2	flotillin complex	Cellular component	21696602
SLC16A5	9121	solute carrier family 16 (monocarboxylate transporter), member 5	monocarboxylic acid transport	Biological process	9425115
XBP1	7494	X-box binding protein 1	transcription from RNA polymerase II promoter	Biological process	-
NEFM	4741	neurofilament, medium polypeptide	microtubule cytoskeleton organization	Biological process	-
ABCC2	1244	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	ATPase activity, coupled to transmembrane movement of substances	Molecular function	-
PPEF1	5475	protein phosphatase, EF-hand calcium binding domain 1	protein serine/threonine phosphatase activity	Molecular function	-
COL13A1	1305	collagen, type XIII, alpha 1	extracellular region	Cellular component	-
RDH13	112724	retinol dehydrogenase 13 (all-trans/9-cis)	mitochondrial inner membrane	Cellular component	-
HIPK2	28996	homeodomain interacting protein kinase 2	positive regulation of angiogenesis	Biological process	19046997
POTEE	445582	POTE ankyrin domain family, member E	molecular_function	Molecular function	-
NT5M	56953	5',3'-nucleotidase, mitochondrial	5'-nucleotidase activity	Molecular function	-
ZNF492	57615	zinc finger protein 492	transcription, DNA-templated	Biological process	-
TRIM29	23650	tripartite motif containing 29	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
PPAP2C	8612	phosphatidic acid phosphatase type 2C	phosphatidate phosphatase activity	Molecular function	-
DYNC1LI2	1783	dynein, cytoplasmic 1, light intermediate chain 2	metabolic process	Biological process	-
NR0B1	190	nuclear receptor subfamily 0, group B, member 1	cytoplasm	Cellular component	16709599
AMT	275	aminomethyltransferase	transaminase activity	Molecular function	-
MSN	4478	moesin	double-stranded RNA binding	Molecular function	21266579
SNF8	11267	SNF8, ESCRT-II complex subunit	endocytic recycling	Biological process	17714434
NOS1	4842	nitric oxide synthase 1 (neuronal)	arginine catabolic process	Biological process	7545544
SEC63	11231	SEC63 homolog (S. cerevisiae)	nitrogen compound metabolic process	Biological process	-
ZDHHC5	25921	zinc finger, DHHC-type containing 5	membrane	Cellular component	19946888
CTNNA1	1495	catenin (cadherin-associated protein), alpha 1, 102kDa	protein heterooligomerization	Biological process	-
KIN	22944	Kin17 DNA and RNA binding protein	cellular response to DNA damage stimulus	Biological process	12853634
PYCR1	5831	pyrroline-5-carboxylate reductase 1	pyrroline-5-carboxylate reductase activity	Molecular function	-
AHI1	54806	Abelson helper integration site 1	identical protein binding	Molecular function	23532844
PSMA1	5682	proteasome (prosome, macropain) subunit, alpha type, 1	cellular nitrogen compound metabolic process	Biological process	-
TK2	7084	thymidine kinase 2, mitochondrial	small molecule metabolic process	Biological process	-
TAGLN2	8407	transgelin 2	actin filament binding	Molecular function	-
DIS3	22894	DIS3 exosome endoribonuclease and 3'-5' exoribonuclease	nucleoplasm	Cellular component	20531389
CXCR4	7852	chemokine (C-X-C motif) receptor 4	actin binding	Molecular function	12421915
COL9A1	1297	collagen, type IX, alpha 1	endoplasmic reticulum lumen	Cellular component	-
ZCCHC11	23318	zinc finger, CCHC domain containing 11	miRNA metabolic process	Biological process	-
PELI1	57162	pellino E3 ubiquitin protein ligase 1	positive regulation of B cell proliferation	Biological process	-
TUBGCP2	10844	tubulin, gamma complex associated protein 2	membrane	Cellular component	19946888
ALOX15	246	arachidonate 15-lipoxygenase	positive regulation of actin filament polymerization	Biological process	-
CTHRC1	115908	collagen triple helix repeat containing 1	frizzled binding	Molecular function	-
TTN	7273	titin	mitotic chromosome condensation	Biological process	9548712
GSK3B	2932	glycogen synthase kinase 3 beta	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
IP6K2	51447	inositol hexakisphosphate kinase 2	inositol hexakisphosphate 1-kinase activity	Molecular function	-
MTERF2	80298	mitochondrial transcription termination factor 2	regulation of transcription, DNA-templated	Biological process	-
KCNH2	3757	potassium channel, voltage gated eag related subfamily H, member 2	protein homodimerization activity	Molecular function	8995352
NDC80	10403	NDC80 kinetochore complex component	mitotic spindle organization	Biological process	14699129
XAF1	54739	XIAP associated factor 1	cytokine-mediated signaling pathway	Biological process	-
NOTCH1	4851	notch 1	distal tubule development	Biological process	-
ID1	3397	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	transforming growth factor beta receptor signaling pathway	Biological process	14522471
OPA1	4976	optic atrophy 1 (autosomal dominant)	negative regulation of release of cytochrome c from mitochondria	Biological process	21149567
KLF12	11278	Kruppel-like factor 12	regulation of transcription from RNA polymerase II promoter	Biological process	10704285
CATSPERB	79820	catsper channel auxiliary subunit beta	cell differentiation	Biological process	-
RAP2C	57826	RAP2C, member of RAS oncogene family	plasma membrane	Cellular component	16213650
EGFR	1956	epidermal growth factor receptor	morphogenesis of an epithelial fold	Biological process	-
GSK3A	2931	glycogen synthase kinase 3 alpha	positive regulation of adrenergic receptor signaling pathway	Biological process	-
ADAMTS19	171019	ADAM metallopeptidase with thrombospondin type 1 motif, 19	metalloendopeptidase activity	Molecular function	-
HLA-DRB5	3127	major histocompatibility complex, class II, DR beta 5	clathrin-coated endocytic vesicle membrane	Cellular component	-
TGFB1	7040	transforming growth factor, beta 1	antigen binding	Molecular function	16754747
GPR161	23432	G protein-coupled receptor 161	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning	Biological process	-
IGHG1	3500	immunoglobulin heavy constant gamma 1 (G1m marker)	complement activation, classical pathway	Biological process	-
TARDBP	23435	TAR DNA binding protein	nucleotide binding	Molecular function	-
ATXN7	6314	ataxin 7	visual perception	Biological process	9288099
RAMP2	10266	receptor (G protein-coupled) activity modifying protein 2	response to hypoxia	Biological process	-
RPS6KB1	6198	ribosomal protein S6 kinase, 70kDa, polypeptide 1	positive regulation of translation	Biological process	18423201
KCNJ11	3767	potassium channel, inwardly rectifying subfamily J, member 11	neuronal cell body	Cellular component	-
TCF21	6943	transcription factor 21	palate development	Biological process	-
LIG4	3981	ligase IV, DNA, ATP-dependent	double-strand break repair via classical nonhomologous end joining	Biological process	24837021
HTR3C	170572	5-hydroxytryptamine (serotonin) receptor 3C, ionotropic	extracellular ligand-gated ion channel activity	Molecular function	-
P2RX7	5027	purinergic receptor P2X, ligand gated ion channel, 7	positive regulation of prostaglandin secretion	Biological process	-
HK3	3101	hexokinase 3 (white cell)	ATP binding	Molecular function	-
MMP19	4327	matrix metallopeptidase 19	angiogenesis	Biological process	-
ENPP1	5167	ectonucleotide pyrophosphatase/phosphodiesterase 1	nucleoside triphosphate catabolic process	Biological process	10513816
CACNA1C	775	calcium channel, voltage-dependent, L type, alpha 1C subunit	postsynaptic density	Cellular component	14140941
SALL1	6299	spalt-like transcription factor 1	forelimb morphogenesis	Biological process	-
SLC9A8	23315	solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8	potassium ion transmembrane transport	Biological process	-
DDX24	57062	DEAD (Asp-Glu-Ala-Asp) box helicase 24	nucleolus	Cellular component	-
BAZ2A	11176	bromodomain adjacent to zinc finger domain, 2A	DNA binding	Molecular function	-
TUBB4A	10382	tubulin, beta 4A class IVa	internode region of axon	Cellular component	-
PRSS2	5645	protease, serine, 2 (trypsin 2)	extracellular matrix	Cellular component	12731883
BBC3	27113	BCL2 binding component 3	cellular response to DNA damage stimulus	Biological process	-
IMPA1	3612	inositol(myo)-1(or 4)-monophosphatase 1	inositol monophosphate phosphatase activity	Molecular function	9462881
PDE4B	5142	phosphodiesterase 4B, cAMP-specific	ion channel binding	Molecular function	-
RNF41	10193	ring finger protein 41, E3 ubiquitin protein ligase	ubiquitin protein ligase activity	Molecular function	18541373
TLN2	83660	talin 2	cell-cell junction assembly	Biological process	15494027
CARD8	22900	caspase recruitment domain family, member 8	nucleoplasm	Cellular component	-
SLC35B2	347734	solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2	carbohydrate metabolic process	Biological process	-
APOC2	344	apolipoprotein C-II	negative regulation of cholesterol transport	Biological process	15778093
RC3H2	54542	ring finger and CCCH-type domains 2	post-embryonic development	Biological process	-
SLC5A12	159963	solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12	integral component of membrane	Cellular component	-
OSR2	116039	odd-skipped related transciption factor 2	embryonic skeletal joint development	Biological process	-
EP300	2033	E1A binding protein p300	circadian rhythm	Biological process	-
CDK7	1022	cyclin-dependent kinase 7	cytoplasm	Cellular component	-
QRSL1	55278	glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1	glutaminyl-tRNAGln biosynthesis via transamidation	Biological process	19805282
TXNDC11	51061	thioredoxin domain containing 11	cell redox homeostasis	Biological process	-
AMELX	265	amelogenin, X-linked	identical protein binding	Molecular function	1734713
CYB5R1	51706	cytochrome b5 reductase 1	integral component of membrane	Cellular component	-
KRT84	3890	keratin 84, type II	hair follicle development	Biological process	10692104
DPAGT1	1798	dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)	UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity	Molecular function	12872255
ACAA2	10449	acetyl-CoA acyltransferase 2	mitochondrion	Cellular component	8241273
IDH3G	3421	isocitrate dehydrogenase 3 (NAD+) gamma	tricarboxylic acid cycle	Biological process	-
ESCO2	157570	establishment of sister chromatid cohesion N-acetyltransferase 2	chromocenter	Cellular component	-
TJAP1	93643	tight junction associated protein 1 (peripheral)	nucleoplasm	Cellular component	-
ALOX12B	242	arachidonate 12-lipoxygenase, 12R type	protein lipidation	Biological process	-
ARHGEF10	9639	Rho guanine nucleotide exchange factor (GEF) 10	mitotic spindle assembly	Biological process	19635168
PDGFB	5155	platelet-derived growth factor beta polypeptide	negative regulation of platelet activation	Biological process	2538439
ACVR1	90	activin A receptor, type I	positive regulation of pathway-restricted SMAD protein phosphorylation	Biological process	19506109
HOXC11	3227	homeobox C11	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	9582375
HLA-DRB3	3125	major histocompatibility complex, class II, DR beta 3	trans-Golgi network membrane	Cellular component	-
HNRNPK	3190	heterogeneous nuclear ribonucleoprotein K	RNA splicing	Biological process	-
SPON2	10417	spondin 2, extracellular matrix protein	mast cell mediated immunity	Biological process	-
CARM1	10498	coactivator-associated arginine methyltransferase 1	regulation of transcription, DNA-templated	Biological process	-
ITCH	83737	itchy E3 ubiquitin protein ligase	negative regulation of type I interferon production	Biological process	-
GLUL	2752	glutamate-ammonia ligase	synaptic transmission	Biological process	-
FOXJ2	55810	forkhead box J2	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	10777590
ADK	132	adenosine kinase	AMP salvage	Biological process	-
SLC16A10	117247	solute carrier family 16 (aromatic amino acid transporter), member 10	transporter activity	Molecular function	-
CREBBP	1387	CREB binding protein	gene expression	Biological process	-
VAC14	55697	Vac14 homolog (S. cerevisiae)	early endosome membrane	Cellular component	-
ALOX15B	247	arachidonate 15-lipoxygenase, type B	positive regulation of peroxisome proliferator activated receptor signaling pathway	Biological process	-
PRLR	5618	prolactin receptor	peptide hormone binding	Molecular function	7984244
HBA2	3040	hemoglobin, alpha 2	oxidation-reduction process	Biological process	19740759
IGKV3-20	28912	immunoglobulin kappa variable 3-20	Fc-epsilon receptor signaling pathway	Biological process	-
ZCCHC12	170261	zinc finger, CCHC domain containing 12	zinc ion binding	Molecular function	-
ANO7	50636	anoctamin 7	nucleus	Cellular component	-
TBCE	6905	tubulin folding cofactor E	microtubule cytoskeleton organization	Biological process	-
GCDH	2639	glutaryl-CoA dehydrogenase	cellular nitrogen compound metabolic process	Biological process	-
DLX1	1745	distal-less homeobox 1	hippocampus development	Biological process	-
HIST1H4I	8294	histone cluster 1, H4i	chromatin silencing at rDNA	Biological process	-
DUSP6	1848	dual specificity phosphatase 6	toll-like receptor 10 signaling pathway	Biological process	-
EIF3K	27335	eukaryotic translation initiation factor 3, subunit K	extracellular exosome	Cellular component	23376485
SAXO1	158297	stabilizer of axonemal microtubules 1	axonemal microtubule	Cellular component	25673876
SH3BGRL3	83442	SH3 domain binding glutamate-rich protein like 3	extracellular exosome	Cellular component	19056867
ATXN10	25814	ataxin 10	perinuclear region of cytoplasm	Cellular component	15201271
CNOT7	29883	CCR4-NOT transcription complex, subunit 7	signal transduction	Biological process	9820826
NUPL2	11097	nucleoporin like 2	nuclear export signal receptor activity	Molecular function	10358091
TBC1D20	128637	TBC1 domain family, member 20	lens fiber cell morphogenesis	Biological process	-
CHAMP1	283489	chromosome alignment maintaining phosphoprotein 1	metal ion binding	Molecular function	-
TAF12	6883	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa	protein heterodimerization activity	Molecular function	-
STK17A	9263	serine/threonine kinase 17a	protein phosphorylation	Biological process	9786912
NDNF	79625	neuron-derived neurotrophic factor	extracellular region	Cellular component	20969804
NUP98	4928	nucleoporin 98kDa	peptide binding	Molecular function	-
FGF3	2248	fibroblast growth factor 3	post-anal tail morphogenesis	Biological process	-
IRAK2	3656	interleukin-1 receptor-associated kinase 2	protein homodimerization activity	Molecular function	10383454
SMAD9	4093	SMAD family member 9	metal ion binding	Molecular function	-
ACP5	54	acid phosphatase 5, tartrate resistant	negative regulation of inflammatory response	Biological process	-
OR5H6	79295	olfactory receptor, family 5, subfamily H, member 6 (gene/pseudogene)	odorant binding	Molecular function	-
GRIK2	2898	glutamate receptor, ionotropic, kainate 2	kainate selective glutamate receptor complex	Cellular component	-
METTL5	29081	methyltransferase like 5	methylation	Biological process	-
SIRT6	51548	sirtuin 6	nucleolus	Cellular component	16079181
BTK	695	Bruton agammaglobulinemia tyrosine kinase	Fc-epsilon receptor signaling pathway	Biological process	-
SGPL1	8879	sphingosine-1-phosphate lyase 1	integral component of endoplasmic reticulum membrane	Cellular component	11018465
XDH	7498	xanthine dehydrogenase	nucleobase-containing small molecule metabolic process	Biological process	-
ADM	133	adrenomedullin	hormone activity	Molecular function	-
POLR2C	5432	polymerase (RNA) II (DNA directed) polypeptide C, 33kDa	somatic stem cell maintenance	Biological process	-
GRB2	2885	growth factor receptor-bound protein 2	extracellular exosome	Cellular component	19056867
IL6	3569	interleukin 6	negative regulation of lipid storage	Biological process	16464856
LRP6	4040	low density lipoprotein receptor-related protein 6	receptor complex	Cellular component	-
PMCH	5367	pro-melanin-concentrating hormone	extracellular region	Cellular component	-
CNTN4	152330	contactin 4	plasma membrane	Cellular component	15106122
LACTB	114294	lactamase, beta	cytoplasm	Cellular component	-
NUP35	129401	nucleoporin 35kDa	cytokine-mediated signaling pathway	Biological process	-
SPATA31A1	647060	SPATA31 subfamily A, member 1	cell differentiation	Biological process	-
SLC9A1	6548	solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1	regulation of stress fiber assembly	Biological process	17565280
VAMP5	10791	vesicle-associated membrane protein 5	cell surface	Cellular component	21151919
FGFR2	2263	fibroblast growth factor receptor 2	extracellular matrix	Cellular component	17959718
ZNF674	641339	zinc finger protein 674	transcription, DNA-templated	Biological process	-
HSPA1B	3304	heat shock 70kDa protein 1B	cytosol	Cellular component	-
HSPB2	3316	heat shock 27kDa protein 2	protein binding	Molecular function	14594798
PALM3	342979	paralemmin 3	protein binding	Molecular function	21187075
MEF2C	4208	myocyte enhancer factor 2C	neuron differentiation	Biological process	-
CDC37	11140	cell division cycle 37	protein binding	Molecular function	11036079
RHOV	171177	ras homolog family member V	cytosol	Cellular component	-
RUNX3	864	runt-related transcription factor 3	sequence-specific DNA binding transcription factor activity	Molecular function	7607690
SLC26A4	5172	solute carrier family 26 (anion exchanger), member 4	brush border membrane	Cellular component	-
SMN1	6606	survival of motor neuron 1, telomeric	Gemini of coiled bodies	Cellular component	11283611
IL4R	3566	interleukin 4 receptor	regulation of cell proliferation	Biological process	-
DSG2	1829	desmoglein 2	regulation of heart rate by cardiac conduction	Biological process	16505173
PLA2G12A	81579	phospholipase A2, group XIIA	biological_process	Biological process	-
ACTR2	10097	ARP2 actin-related protein 2 homolog (yeast)	movement of cell or subcellular component	Biological process	9230079
CCDC79	283847	coiled-coil domain containing 79	DNA binding	Molecular function	-
GSTP1	2950	glutathione S-transferase pi 1	negative regulation of MAP kinase activity	Biological process	11408560
PPP1R15A	23645	protein phosphatase 1, regulatory subunit 15A	positive regulation of peptidyl-serine dephosphorylation	Biological process	11564868
DNMT3A	1788	DNA (cytosine-5-)-methyltransferase 3 alpha	protein binding	Molecular function	16357870
RNF14	9604	ring finger protein 14	cytoplasm	Cellular component	-
CASP8	841	caspase 8, apoptosis-related cysteine peptidase	mitochondrion	Cellular component	-
BAP1	8314	BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)	nucleus	Cellular component	18757409
PPP1CA	5499	protein phosphatase 1, catalytic subunit, alpha isozyme	dephosphorylation	Biological process	22311981
DVL1	1855	dishevelled segment polarity protein 1	canonical Wnt signaling pathway	Biological process	11113207
QDPR	5860	quinoid dihydropteridine reductase	liver development	Biological process	-
COCH	1690	cochlin	extracellular matrix	Cellular component	22610276
TGFB1	7040	transforming growth factor, beta 1	protein export from nucleus	Biological process	17438144
HELT	391723	helt bHLH transcription factor	GABAergic neuron differentiation in basal ganglia	Biological process	-
SERPINF2	5345	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2	fibrinogen complex	Cellular component	17317851
DGAT2	84649	diacylglycerol O-acyltransferase 2	glycerol metabolic process	Biological process	-
HSF1	3297	heat shock transcription factor 1	chromatin binding	Molecular function	-
GCSAM	257144	germinal center-associated, signaling and motility	protein binding	Molecular function	20844236
KRAS	3845	Kirsten rat sarcoma viral oncogene homolog	innate immune response	Biological process	-
CHRDL1	91851	chordin-like 1	eye development	Biological process	22284829
ZNF211	10520	zinc finger protein 211	metal ion binding	Molecular function	-
CD70	970	CD70 molecule	signal transduction	Biological process	8387892
NME1	4830	NME/NM23 nucleoside diphosphate kinase 1	cytoplasm	Cellular component	16130169
SYT16	83851	synaptotagmin XVI	regulation of calcium ion-dependent exocytosis	Biological process	-
FGFR2	2263	fibroblast growth factor receptor 2	integral component of membrane	Cellular component	1697263
SLC1A7	6512	solute carrier family 1 (glutamate transporter), member 7	glutamate secretion	Biological process	-
IL10	3586	interleukin 10	negative regulation of endothelial cell apoptotic process	Biological process	16034134
FBXW7	55294	F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase	cellular response to UV	Biological process	17873522
ITGAD	3681	integrin, alpha D	cell surface	Cellular component	20563599
IL18	3606	interleukin 18	extracellular region	Cellular component	11598150
RAB27A	5873	RAB27A, member RAS oncogene family	late endosome	Cellular component	17237785
TMC4	147798	transmembrane channel-like 4	integral component of membrane	Cellular component	-
RHBDF1	64285	rhomboid 5 homolog 1 (Drosophila)	cell migration	Biological process	18832597
MED1	5469	mediator complex subunit 1	mRNA transcription from RNA polymerase II promoter	Biological process	-
RB1	5925	retinoblastoma 1	negative regulation of epithelial cell proliferation	Biological process	-
IDE	3416	insulin-degrading enzyme	ubiquitin homeostasis	Biological process	21185309
PC	5091	pyruvate carboxylase	mitochondrion	Cellular component	-
EZR	7430	ezrin	cell periphery	Cellular component	22291017
RPS27A	6233	ribosomal protein S27a	toll-like receptor 9 signaling pathway	Biological process	-
FXN	2395	frataxin	cellular response to hydrogen peroxide	Biological process	15641778
BSND	7809	barttin CLCNK-type chloride channel accessory beta subunit	plasma membrane	Cellular component	-
USP7	7874	ubiquitin specific peptidase 7 (herpes virus-associated)	cytosol	Cellular component	11279055
IFNA10	3446	interferon, alpha 10	humoral immune response	Biological process	-
POT1	25913	protection of telomeres 1	nucleoplasm	Cellular component	-
TONSL	4796	tonsoku-like, DNA repair protein	nuclear replication fork	Cellular component	21055983
JUNB	3726	jun B proto-oncogene	transcription corepressor activity	Molecular function	2513129
PEX5	5830	peroxisomal biogenesis factor 5	protein targeting to peroxisome	Biological process	9668159
FASN	2194	fatty acid synthase	enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity	Molecular function	-
PKD2	5311	polycystic kidney disease 2 (autosomal dominant)	cellular response to osmotic stress	Biological process	16025301
TMED7	51014	transmembrane emp24 protein transport domain containing 7	integral component of membrane	Cellular component	-
ALG3	10195	ALG3, alpha-1,3- mannosyltransferase	alpha-1,3-mannosyltransferase activity	Molecular function	10581255
NLGN1	22871	neuroligin 1	regulation of respiratory gaseous exchange by neurological system process	Biological process	-
MRPS23	51649	mitochondrial ribosomal protein S23	protein binding	Molecular function	25416956
OR4D5	219875	olfactory receptor, family 4, subfamily D, member 5	detection of chemical stimulus involved in sensory perception	Biological process	-
UTRN	7402	utrophin	muscle organ development	Biological process	9288751
CETN2	1069	centrin, EF-hand protein, 2	cell division	Biological process	-
MFNG	4242	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	extracellular space	Cellular component	9187150
LIN7B	64130	lin-7 homolog B (C. elegans)	protein transport	Biological process	-
SLC9A3	6550	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3	transmembrane transport	Biological process	-
ZAP70	7535	zeta-chain (TCR) associated protein kinase 70kDa	cytoplasm	Cellular component	12359715
DLG1	1739	discs, large homolog 1 (Drosophila)	perinuclear region of cytoplasm	Cellular component	21615688
GOLPH3	64083	golgi phosphoprotein 3 (coat-protein)	cytosol	Cellular component	16263763
NUP54	53371	nucleoporin 54kDa	mitotic cell cycle	Biological process	-
NDUFAF7	55471	NADH dehydrogenase (ubiquinone) complex I, assembly factor 7	methyltransferase activity	Molecular function	20406883
CUL4A	8451	cullin 4A	somatic stem cell maintenance	Biological process	-
DAD1	1603	defender against cell death 1	blastocyst development	Biological process	-
DRD1	1812	dopamine receptor D1	neuronal action potential	Biological process	-
SOX2	6657	SRY (sex determining region Y)-box 2	diencephalon morphogenesis	Biological process	-
STRN4	29888	striatin, calmodulin binding protein 4	protein binding	Molecular function	20195357
SRGN	5552	serglycin	collagen binding	Molecular function	-
ZDHHC11	79844	zinc finger, DHHC-type containing 11	metabolic process	Biological process	-
AGTR2	186	angiotensin II receptor, type 2	blood vessel remodeling	Biological process	17159080
SRC	6714	SRC proto-oncogene, non-receptor tyrosine kinase	positive regulation of epithelial cell migration	Biological process	18054784
RPL3	6122	ribosomal protein L3	viral transcription	Biological process	-
AURKA	6790	aurora kinase A	midbody	Cellular component	19774610
CHST1	8534	carbohydrate (keratan sulfate Gal-6) sulfotransferase 1	integral component of membrane	Cellular component	9405439
GCNT4	51301	glucosaminyl (N-acetyl) transferase 4, core 2	O-glycan processing	Biological process	-
GFRA4	64096	GDNF family receptor alpha 4	negative regulation of ossification	Biological process	-
ZNF554	115196	zinc finger protein 554	regulation of transcription, DNA-templated	Biological process	-
RTN4	57142	reticulon 4	regulation of apoptotic process	Biological process	11126360
LYPLA1	10434	lysophospholipase I	cytosol	Cellular component	-
TRPS1	7227	trichorhinophalangeal syndrome I	negative regulation of transcription from RNA polymerase II promoter	Biological process	12885770
MPL	4352	MPL proto-oncogene, thrombopoietin receptor	platelet activation	Biological process	-
PRKCZ	5590	protein kinase C, zeta	negative regulation of hydrolase activity	Biological process	-
GLI3	2737	GLI family zinc finger 3	negative regulation of canonical Wnt signaling pathway	Biological process	17331723
ZBTB9	221504	zinc finger and BTB domain containing 9	DNA binding	Molecular function	-
HIST1H4F	8361	histone cluster 1, H4f	small GTPase mediated signal transduction	Biological process	-
ENPP1	5167	ectonucleotide pyrophosphatase/phosphodiesterase 1	nucleotide diphosphatase activity	Molecular function	-
GRID2	2895	glutamate receptor, ionotropic, delta 2	ion transmembrane transport	Biological process	-
ALG1	56052	ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase	dolichol-linked oligosaccharide biosynthetic process	Biological process	-
IL10RB	3588	interleukin 10 receptor, beta	immune response	Biological process	9463407
SUCLG1	8802	succinate-CoA ligase, alpha subunit	succinyl-CoA metabolic process	Biological process	-
FBXW8	26259	F-box and WD repeat domain containing 8	Cul7-RING ubiquitin ligase complex	Cellular component	18498745
CALCA	796	calcitonin-related polypeptide alpha	regulation of blood pressure	Biological process	1318039
PPP1R10	5514	protein phosphatase 1, regulatory subunit 10	poly(A) RNA binding	Molecular function	22681889
BBS9	27241	Bardet-Biedl syndrome 9	BBSome	Cellular component	17574030
RPA3	6119	replication protein A3, 14kDa	nucleotide-excision repair	Biological process	-
OR14J1	442191	olfactory receptor, family 14, subfamily J, member 1	odorant binding	Molecular function	-
DICER1	23405	dicer 1, ribonuclease type III	spinal cord motor neuron differentiation	Biological process	-
ARID3C	138715	AT rich interactive domain 3C (BRIGHT-like)	DNA binding	Molecular function	-
SMAD3	4088	SMAD family member 3	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	21947082
CTHRC1	115908	collagen triple helix repeat containing 1	positive regulation of osteoblast proliferation	Biological process	-
SMC3	9126	structural maintenance of chromosomes 3	cohesin complex	Cellular component	9506951
PRKAG3	53632	protein kinase, AMP-activated, gamma 3 non-catalytic subunit	fatty acid biosynthetic process	Biological process	-
NRSN1	140767	neurensin 1	neuron projection	Cellular component	-
VAV2	7410	vav 2 guanine nucleotide exchange factor	Fc-gamma receptor signaling pathway involved in phagocytosis	Biological process	-
CHRNB4	1143	cholinergic receptor, nicotinic, beta 4 (neuronal)	acetylcholine receptor activity	Molecular function	8906617
GRM4	2914	glutamate receptor, metabotropic 4	calcium-dependent protein binding	Molecular function	-
CUL5	8065	cullin 5	receptor activity	Molecular function	9581826
NUDT16	131870	nudix (nucleoside diphosphate linked moiety X)-type motif 16	cobalt ion binding	Molecular function	17567574
RHBDD3	25807	rhomboid domain containing 3	integral component of membrane	Cellular component	-
ATP6V1E2	90423	ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2	protein binding	Molecular function	21516116
TAP2	6891	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	cytosol to ER transport	Biological process	7538543
CAPN3	825	calpain 3, (p94)	positive regulation of transcription, DNA-templated	Biological process	18073330
SMARCA4	6597	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	protein binding	Molecular function	10078207
MACROD2	140733	MACRO domain containing 2	purine nucleoside metabolic process	Biological process	21257746
SELE	6401	selectin E	oligosaccharide binding	Molecular function	7680663
BMP4	652	bone morphogenetic protein 4	cardiac septum development	Biological process	18076106
GM2A	2760	GM2 ganglioside activator	beta-N-acetylgalactosaminidase activity	Molecular function	-
SCD	6319	stearoyl-CoA desaturase (delta-9-desaturase)	endoplasmic reticulum	Cellular component	-
ATF4	468	activating transcription factor 4	gamma-aminobutyric acid signaling pathway	Biological process	-
STK11	6794	serine/threonine kinase 11	spermatid development	Biological process	-
PARK7	11315	parkinson protein 7	positive regulation of protein kinase B signaling	Biological process	22492997
NTS	4922	neurotensin	signal transduction	Biological process	8954810
FKBP4	2288	FK506 binding protein 4, 59kDa	FK506 binding	Molecular function	1376003
PRMT1	3276	protein arginine methyltransferase 1	neuron projection development	Biological process	18773938
AQP1	358	aquaporin 1 (Colton blood group)	cellular response to dexamethasone stimulus	Biological process	16711029
LYVE1	10894	lymphatic vessel endothelial hyaluronan receptor 1	glycosaminoglycan metabolic process	Biological process	-
SLC25A24	29957	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24	cellular response to oxidative stress	Biological process	22015608
AGTR1	185	angiotensin II receptor, type 1	positive regulation of cytosolic calcium ion concentration	Biological process	1567413
PLA2G5	5322	phospholipase A2, group V	phosphatidylcholine acyl-chain remodeling	Biological process	-
UCP3	7352	uncoupling protein 3 (mitochondrial, proton carrier)	response to cold	Biological process	-
SLC16A10	117247	solute carrier family 16 (aromatic amino acid transporter), member 10	ion transmembrane transport	Biological process	-
SPRR2B	6701	small proline-rich protein 2B	keratinocyte differentiation	Biological process	8325635
SDHC	6391	succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa	succinate dehydrogenase (ubiquinone) activity	Molecular function	-
PPARG	5468	peroxisome proliferator-activated receptor gamma	estrogen receptor binding	Molecular function	-
KCNS3	3790	potassium voltage-gated channel, modifier subfamily S, member 3	voltage-gated potassium channel complex	Cellular component	-
CASP5	838	caspase 5, apoptosis-related cysteine peptidase	regulation of apoptotic process	Biological process	-
FXYD1	5348	FXYD domain containing ion transport regulator 1	chloride channel complex	Cellular component	-
PLSCR4	57088	phospholipid scramblase 4	SH3 domain binding	Molecular function	-
C1QBP	708	complement component 1, q subcomponent binding protein	mRNA binding	Molecular function	-
HSPA8	3312	heat shock 70kDa protein 8	regulation of cell cycle	Biological process	-
FAM3B	54097	family with sequence similarity 3, member B	apoptotic process	Biological process	-
TMEM173	340061	transmembrane protein 173	positive regulation of defense response to virus by host	Biological process	18818105
TECTA	7007	tectorin alpha	extracellular exosome	Cellular component	19056867
MZB1	51237	marginal zone B and B1 cell-specific protein	positive regulation of cell proliferation	Biological process	-
WDHD1	11169	WD repeat and HMG-box DNA binding protein 1	chromosome, centromeric region	Cellular component	-
RAB8B	51762	RAB8B, member RAS oncogene family	TPR domain binding	Molecular function	-
SF3B1	23451	splicing factor 3b, subunit 1, 155kDa	nuclear speck	Cellular component	-
PLD6	201164	phospholipase D family, member 6	meiotic nuclear division	Biological process	-
SLC33A1	9197	solute carrier family 33 (acetyl-CoA transporter), member 1	membrane	Cellular component	19946888
PPP2R5D	5528	protein phosphatase 2, regulatory subunit B', delta	toll-like receptor 5 signaling pathway	Biological process	-
CXCL10	3627	chemokine (C-X-C motif) ligand 10	cellular response to heat	Biological process	-
NDST3	9348	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3	deacetylase activity	Molecular function	-
CACNB4	785	calcium channel, voltage-dependent, beta 4 subunit	membrane depolarization	Biological process	-
P2RX3	5024	purinergic receptor P2X, ligand gated ion channel, 3	peristalsis	Biological process	-
MTA2	9219	metastasis associated 1 family, member 2	chromatin assembly or disassembly	Biological process	10444591
RCAN1	1827	regulator of calcineurin 1	cytoplasm	Cellular component	-
COL17A1	1308	collagen, type XVII, alpha 1	plasma membrane	Cellular component	-
APLN	8862	apelin	immune response	Biological process	10525157
PER2	8864	period circadian clock 2	response to ischemia	Biological process	-
NDUFB1	4707	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa	integral component of membrane	Cellular component	-
CRHR1	1394	corticotropin releasing hormone receptor 1	integral component of membrane	Cellular component	23863939
CORO7	79585	coronin 7	trans-Golgi network	Cellular component	24768539
TBC1D23	55773	TBC1 domain family, member 23	positive regulation of interleukin-6 production	Biological process	-
EEF2KMT	196483	eukaryotic elongation factor 2 lysine methyltransferase	protein binding	Molecular function	16189514
ROM1	6094	retinal outer segment membrane protein 1	integral component of plasma membrane	Cellular component	1610568
TMED10	10972	transmembrane emp24-like trafficking protein 10 (yeast)	endoplasmic reticulum-Golgi intermediate compartment	Cellular component	12237308
COL3A1	1281	collagen, type III, alpha 1	platelet-derived growth factor binding	Molecular function	8900172
NCF2	4688	neutrophil cytosolic factor 2	superoxide anion generation	Biological process	7938008
CENPE	1062	centromere protein E, 312kDa	multicellular organismal development	Biological process	-
LSM6	11157	LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)	protein binding	Molecular function	15231747
LOXHD1	125336	lipoxygenase homology domains 1	calcium ion transmembrane transport	Biological process	-
ZNF420	147923	zinc finger protein 420	DNA binding	Molecular function	-
EXOC1	55763	exocyst complex component 1	exocytosis	Biological process	11406615
AGO2	27161	argonaute RISC catalytic component 2	innate immune response	Biological process	-
NR2C2	7182	nuclear receptor subfamily 2, group C, member 2	nervous system development	Biological process	9006963
SATB2	23314	SATB homeobox 2	osteoblast development	Biological process	-
CARTPT	9607	CART prepropeptide	negative regulation of osteoclast differentiation	Biological process	16614075
OR5K3	403277	olfactory receptor, family 5, subfamily K, member 3	olfactory receptor activity	Molecular function	-
FBXO40	51725	F-box protein 40	cytoplasm	Cellular component	-
TSSK2	23617	testis-specific serine kinase 2	protein binding	Molecular function	15044604
DEFB125	245938	defensin, beta 125	extracellular region	Cellular component	-
NTRK1	4914	neurotrophic tyrosine kinase, receptor, type 1	nerve growth factor receptor activity	Molecular function	15488758
JCHAIN	3512	joining chain of multimeric IgA and IgM	extracellular exosome	Cellular component	19199708
PPP1R1B	84152	protein phosphatase 1, regulatory (inhibitor) subunit 1B	transcription, DNA-templated	Biological process	-
DACT1	51339	dishevelled-binding antagonist of beta-catenin 1	cell junction	Cellular component	-
C4BPB	725	complement component 4 binding protein, beta	other organism cell	Cellular component	22333221
SPG20	23111	spastic paraplegia 20 (Troyer syndrome)	plasma membrane	Cellular component	-
IRG1	730249	immunoresponsive 1 homolog (mouse)	propionate catabolic process	Biological process	-
LRMP	4033	lymphoid-restricted membrane protein	spindle pole	Cellular component	-
TBCEL	219899	tubulin folding cofactor E-like	protein binding	Molecular function	25416956
BAG5	9529	BCL2-associated athanogene 5	regulation of cellular response to heat	Biological process	-
DUSP26	78986	dual specificity phosphatase 26 (putative)	cytoplasm	Cellular component	15796912
CSTF3	1479	cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa	nucleoplasm	Cellular component	-
SPAG17	200162	sperm associated antigen 17	sperm flagellum	Cellular component	-
OR2AG2	338755	olfactory receptor, family 2, subfamily AG, member 2	olfactory receptor activity	Molecular function	-
GSN	2934	gelsolin	actin cap	Cellular component	23575248
ADH1B	125	alcohol dehydrogenase 1B (class I), beta polypeptide	xenobiotic metabolic process	Biological process	-
CKS1B	1163	CDC28 protein kinase regulatory subunit 1B	G1/S transition of mitotic cell cycle	Biological process	-
SOD1	6647	superoxide dismutase 1, soluble	plasma membrane	Cellular component	17077646
DCC	1630	DCC netrin 1 receptor	integral component of membrane	Cellular component	-
AGRN	375790	agrin	signal transduction	Biological process	9652404
PKD1	5310	polycystic kidney disease 1 (autosomal dominant)	placenta blood vessel development	Biological process	-
TRPM5	29850	transient receptor potential cation channel, subfamily M, member 5	transmembrane transport	Biological process	-
OGDH	4967	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)	oxoglutarate dehydrogenase complex	Cellular component	-
HAX1	10456	HCLS1 associated protein X-1	sarcoplasmic reticulum	Cellular component	-
OPRD1	4985	opioid receptor, delta 1	neuron projection	Cellular component	-
SYNDIG1	79953	synapse differentiation inducing 1	positive regulation of synapse assembly	Biological process	20152115
SH3GLB1	51100	SH3-domain GRB2-like endophilin B1	apoptotic process	Biological process	-
OR2T6	254879	olfactory receptor, family 2, subfamily T, member 6	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
RNF2	6045	ring finger protein 2	ligase activity	Molecular function	-
CCR5	1234	chemokine (C-C motif) receptor 5 (gene/pseudogene)	actin binding	Molecular function	12421915
NSMAF	8439	neutral sphingomyelinase (N-SMase) activation associated factor	extrinsic component of membrane	Cellular component	-
SLIT3	6586	slit homolog 3 (Drosophila)	response to cortisol	Biological process	18566128
CCBL2	56267	cysteine conjugate-beta lyase 2	cellular amino acid metabolic process	Biological process	-
EMG1	10436	EMG1 N1-specific pseudouridine methyltransferase	rRNA methylation	Biological process	20047967
MYF5	4617	myogenic factor 5	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
TCF3	6929	transcription factor 3	nucleoplasm	Cellular component	-
ZPR1	8882	ZPR1 zinc finger	trophectodermal cell proliferation	Biological process	-
TFCP2	7024	transcription factor CP2	protein binding	Molecular function	21516116
MAF1	84232	MAF1 homolog (S. cerevisiae)	RNA polymerase III type 3 promoter DNA binding	Molecular function	20233713
DCD	117159	dermcidin	killing of cells of other organism	Biological process	-
IL7R	3575	interleukin 7 receptor	cell morphogenesis	Biological process	-
SLC38A7	55238	solute carrier family 38, member 7	L-glutamate transmembrane transport	Biological process	-
POLR3B	55703	polymerase (RNA) III (DNA directed) polypeptide B	transcription elongation from RNA polymerase III promoter	Biological process	-
ATP10D	57205	ATPase, class V, type 10D	protein binding	Molecular function	21914794
CLSPN	63967	claspin	programmed cell death	Biological process	-
DPYSL3	1809	dihydropyrimidinase-like 3	phosphoprotein binding	Molecular function	-
IMPA2	3613	inositol(myo)-1(or 4)-monophosphatase 2	inositol monophosphate 3-phosphatase activity	Molecular function	-
MYO5A	4644	myosin VA (heavy chain 12, myoxin)	long-chain fatty acid biosynthetic process	Biological process	-
GOLPH3	64083	golgi phosphoprotein 3 (coat-protein)	asymmetric Golgi ribbon formation	Biological process	19837035
ENO1	2023	enolase 1, (alpha)	cytosol	Cellular component	-
GALNT1	2589	polypeptide N-acetylgalactosaminyltransferase 1	post-translational protein modification	Biological process	-
UCK1	83549	uridine-cytidine kinase 1	pyrimidine nucleoside salvage	Biological process	-
HP	3240	haptoglobin	extracellular region	Cellular component	-
OR2G6	391211	olfactory receptor, family 2, subfamily G, member 6	sensory perception of smell	Biological process	-
REN	5972	renin	peptidase activity	Molecular function	12045255
BAG1	573	BCL2-associated athanogene	intracellular signal transduction	Biological process	8947043
MEF2D	4209	myocyte enhancer factor 2D	RNA polymerase II regulatory region sequence-specific DNA binding	Molecular function	20590529
FGR	2268	FGR proto-oncogene, Src family tyrosine kinase	ruffle membrane	Cellular component	-
EXOC6	54536	exocyst complex component 6	plasma membrane	Cellular component	-
UFD1L	7353	ubiquitin fusion degradation 1 like (yeast)	cytosol	Cellular component	-
CXXC4	80319	CXXC finger protein 4	zygotic specification of dorsal/ventral axis	Biological process	-
GAB1	2549	GRB2-associated binding protein 1	Fc-epsilon receptor signaling pathway	Biological process	-
PSMC4	5704	proteasome (prosome, macropain) 26S subunit, ATPase, 4	proteasome-activating ATPase activity	Molecular function	-
PLIN2	123	perilipin 2	small molecule metabolic process	Biological process	-
GIP	2695	gastric inhibitory polypeptide	long-term synaptic potentiation	Biological process	-
MUS81	80198	MUS81 structure-specific endonuclease subunit	nucleus	Cellular component	-
GP9	2815	glycoprotein IX (platelet)	cell adhesion	Biological process	-
UPF1	5976	UPF1 regulator of nonsense transcripts homolog (yeast)	gene expression	Biological process	-
PDE4A	5141	phosphodiesterase 4A, cAMP-specific	cAMP binding	Molecular function	8413254
PARP10	84875	poly (ADP-ribose) polymerase family, member 10	negative regulation of NF-kappaB transcription factor activity	Biological process	23575687
TP53I3	9540	tumor protein p53 inducible protein 3	NADP metabolic process	Biological process	19349281
UGT2B28	54490	UDP glucuronosyltransferase 2 family, polypeptide B28	endoplasmic reticulum	Cellular component	11300766
PCYT2	5833	phosphate cytidylyltransferase 2, ethanolamine	phosphatidylethanolamine biosynthetic process	Biological process	-
ITK	3702	IL2-inducible T-cell kinase	extrinsic component of cytoplasmic side of plasma membrane	Cellular component	-
CDH5	1003	cadherin 5, type 2 (vascular endothelium)	bicellular tight junction	Cellular component	-
ITGB1BP1	9270	integrin beta 1 binding protein 1	integrin-mediated signaling pathway	Biological process	11919189
OR9I1	219954	olfactory receptor, family 9, subfamily I, member 1	odorant binding	Molecular function	-
MAEA	10296	macrophage erythroblast attacher	negative regulation of myeloid cell apoptotic process	Biological process	9763581
STK16	8576	serine/threonine kinase 16	membrane	Cellular component	-
APOA2	336	apolipoprotein A-II	protein oxidation	Biological process	12576517
CTSG	1511	cathepsin G	angiotensin maturation	Biological process	-
CCL3	6348	chemokine (C-C motif) ligand 3	CCR1 chemokine receptor binding	Molecular function	10660125
FAM109B	150368	family with sequence similarity 109, member B	trans-Golgi network	Cellular component	21233288
FOXF2	2295	forkhead box F2	transcription factor complex	Cellular component	9722567
PHEX	5251	phosphate regulating endopeptidase homolog, X-linked	integral component of plasma membrane	Cellular component	9593714
LMNA	4000	lamin A/C	structural molecule activity	Molecular function	3453101
CTSG	1511	cathepsin G	extracellular matrix organization	Biological process	-
HERC2	8924	HECT and RLD domain containing E3 ubiquitin protein ligase 2	zinc ion binding	Molecular function	-
DNAJC1	64215	DnaJ (Hsp40) homolog, subfamily C, member 1	DNA binding	Molecular function	-
CREBBP	1387	CREB binding protein	signal transducer activity	Molecular function	7913207
SLC7A7	9056	solute carrier family 7 (amino acid transporter light chain, y+L system), member 7	leukocyte migration	Biological process	-
RPS6KA2	6196	ribosomal protein S6 kinase, 90kDa, polypeptide 2	positive regulation of gene expression	Biological process	-
HIST1H3C	8352	histone cluster 1, H3c	small GTPase mediated signal transduction	Biological process	-
SDHAF1	644096	succinate dehydrogenase complex assembly factor 1	iron-sulfur cluster assembly	Biological process	19465911
NRF1	4899	nuclear respiratory factor 1	organelle organization	Biological process	-
TCEB3B	51224	transcription elongation factor B polypeptide 3B (elongin A2)	protein binding	Molecular function	25416956
ATP5J	522	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)	Cellular component	-
C1QL1	10882	complement component 1, q subcomponent-like 1	molecular_function	Molecular function	-
PRDX2	7001	peroxiredoxin 2	cytosol	Cellular component	-
ADAMTS16	170690	ADAM metallopeptidase with thrombospondin type 1 motif, 16	proteinaceous extracellular matrix	Cellular component	-
SERF2	10169	small EDRK-rich factor 2	molecular_function	Molecular function	-
BACE2	25825	beta-site APP-cleaving enzyme 2	beta-amyloid metabolic process	Biological process	-
TET2	54790	tet methylcytosine dioxygenase 2	regulation of gene expression, epigenetic	Biological process	-
LIMD2	80774	LIM domain containing 2	protein binding	Molecular function	25416956
RPS3A	6189	ribosomal protein S3A	cytosolic small ribosomal subunit	Cellular component	15883184
JADE3	9767	jade family PHD finger 3	protein binding	Molecular function	25416956
YBX2	51087	Y box binding protein 2	lipid binding	Molecular function	-
SMAD6	4091	SMAD family member 6	negative regulation of apoptotic process	Biological process	19047146
KIF3A	11127	kinesin family member 3A	microtubule binding	Molecular function	-
ZBTB6	10773	zinc finger and BTB domain containing 6	DNA binding	Molecular function	7958847
HCK	3055	HCK proto-oncogene, Src family tyrosine kinase	viral process	Biological process	-
TREX2	11219	three prime repair exonuclease 2	3'-5'-exodeoxyribonuclease activity	Molecular function	11279105
IFNA14	3448	interferon, alpha 14	cytokine-mediated signaling pathway	Biological process	-
CEBPA	1050	CCAAT/enhancer binding protein (C/EBP), alpha	protein homodimerization activity	Molecular function	-
SF1	7536	splicing factor 1	zinc ion binding	Molecular function	-
ITPR3	3710	inositol 1,4,5-trisphosphate receptor, type 3	small molecule metabolic process	Biological process	-
HDAC4	9759	histone deacetylase 4	regulation of protein binding	Biological process	19071119
AFP	174	alpha-fetoprotein	transport	Biological process	-
NGFR	4804	nerve growth factor receptor	neuronal postsynaptic density	Cellular component	-
TRAF4	9618	TNF receptor-associated factor 4	ubiquitin protein ligase binding	Molecular function	11279055
PICALM	8301	phosphatidylinositol binding clathrin assembly protein	positive regulation of beta-amyloid formation	Biological process	24577224
IL6	3569	interleukin 6	response to caffeine	Biological process	-
IKBKAP	8518	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein	phosphorylase kinase regulator activity	Molecular function	11818576
CBX4	8535	chromobox homolog 4	chromatin modification	Biological process	-
KDF1	126695	keratinocyte differentiation factor 1	cell cortex	Cellular component	-
ZDHHC13	54503	zinc finger, DHHC-type containing 13	magnesium ion transmembrane transporter activity	Molecular function	-
COBL	23242	cordon-bleu WH2 repeat protein	dendritic growth cone	Cellular component	-
HIST1H2BI	8346	histone cluster 1, H2bi	nucleosome assembly	Biological process	422550
EYA2	2139	EYA transcriptional coactivator and phosphatase 2	histone dephosphorylation	Biological process	19351884
IRF5	3663	interferon regulatory factor 5	positive regulation of interferon-beta production	Biological process	22412986
NUPL2	11097	nucleoporin like 2	viral transcription	Biological process	-
SVEP1	79987	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1	cytoplasm	Cellular component	-
DTNA	1837	dystrobrevin, alpha	synapse	Cellular component	-
COL4A1	1282	collagen, type IV, alpha 1	extracellular matrix constituent conferring elasticity	Molecular function	16107487
TWIST2	117581	twist family bHLH transcription factor 2	negative regulation of cell proliferation	Biological process	-
THOC5	8563	THO complex 5	nuclear speck	Cellular component	-
IL12B	3593	interleukin 12B	interleukin-12 complex	Cellular component	11114383
PYCARD	29108	PYD and CARD domain containing	NLRP1 inflammasome complex	Cellular component	12191486
STUB1	10273	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase	cytoplasm	Cellular component	-
SATB1	6304	SATB homeobox 1	nucleoplasm	Cellular component	-
ALG2	85365	ALG2, alpha-1,3/1,6-mannosyltransferase	nucleus	Cellular component	11278427
PARD3	56288	par-3 family cell polarity regulator	protein kinase C binding	Molecular function	-
LMAN1	3998	lectin, mannose-binding, 1	ER to Golgi transport vesicle membrane	Cellular component	-
MAPK7	5598	mitogen-activated protein kinase 7	MyD88-independent toll-like receptor signaling pathway	Biological process	-
LHX1	3975	LIM homeobox 1	pattern specification process	Biological process	-
HNRNPK	3190	heterogeneous nuclear ribonucleoprotein K	membrane	Cellular component	19946888
ZNF207	7756	zinc finger protein 207	protein stabilization	Biological process	24462186
MICALL1	85377	MICAL-like 1	extrinsic component of membrane	Cellular component	19864458
PSMD2	5708	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	G1/S transition of mitotic cell cycle	Biological process	-
PPIF	10105	peptidylprolyl isomerase F	negative regulation of ATPase activity	Biological process	-
SRC	6714	SRC proto-oncogene, non-receptor tyrosine kinase	enzyme binding	Molecular function	21724833
E2F1	1869	E2F transcription factor 1	Notch signaling pathway	Biological process	-
GHRH	2691	growth hormone releasing hormone	cAMP-mediated signaling	Biological process	7680413
PRELP	5549	proline/arginine-rich end leucine-rich repeat protein	keratan sulfate catabolic process	Biological process	-
SUGT1	10910	SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)	positive regulation by host of symbiont catalytic activity	Biological process	23935490
DOCK1	1793	dedicator of cytokinesis 1	blood coagulation	Biological process	-
SGMS1	259230	sphingomyelin synthase 1	phosphorylation	Biological process	-
MAPK7	5598	mitogen-activated protein kinase 7	cell cycle	Biological process	-
EFNA4	1945	ephrin-A4	osteoclast differentiation	Biological process	-
IL18RAP	8807	interleukin 18 receptor accessory protein	cell surface receptor signaling pathway	Biological process	9792649
CDK2	1017	cyclin-dependent kinase 2	peptidyl-serine phosphorylation	Biological process	23184662
HRAS	3265	Harvey rat sarcoma viral oncogene homolog	regulation of synaptic transmission, GABAergic	Biological process	-
RASAL1	8437	RAS protein activator like 1 (GAP1 like)	phospholipid binding	Molecular function	9751798
GABRB3	2562	gamma-aminobutyric acid (GABA) A receptor, beta 3	postsynaptic membrane	Cellular component	-
PIDD1	55367	p53-induced death domain protein 1	Golgi apparatus	Cellular component	-
ARL2BP	23568	ADP-ribosylation factor-like 2 binding protein	cytosol	Cellular component	-
TAOK2	9344	TAO kinase 2	focal adhesion assembly	Biological process	10660600
IGBP1	3476	immunoglobulin (CD79A) binding protein 1	protein binding	Molecular function	16085932
SNX8	29886	sorting nexin 8	early endosome membrane	Cellular component	19782049
CHUK	1147	conserved helix-loop-helix ubiquitous kinase	mammary gland alveolus development	Biological process	-
DST	667	dystonin	axon	Cellular component	-
EAF1	85403	ELL associated factor 1	cytoplasm	Cellular component	-
OR6A2	8590	olfactory receptor, family 6, subfamily A, member 2	G-protein coupled receptor activity	Molecular function	-
WWOX	51741	WW domain containing oxidoreductase	microvillus	Cellular component	19366691
APPL2	55198	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2	cell cycle	Biological process	-
DPCD	25911	deleted in primary ciliary dyskinesia homolog (mouse)	sperm motility	Biological process	-
BOC	91653	BOC cell adhesion associated, oncogene regulated	positive regulation of muscle cell differentiation	Biological process	-
GAS7	8522	growth arrest-specific 7	actin filament	Cellular component	-
NDST4	64579	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4	deacetylase activity	Molecular function	-
KDM5D	8284	lysine (K)-specific demethylase 5D	zinc ion binding	Molecular function	-
PPP1R13L	10848	protein phosphatase 1, regulatory subunit 13 like	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
MAPKAPK2	9261	mitogen-activated protein kinase-activated protein kinase 2	extracellular exosome	Cellular component	18570454
TH	7054	tyrosine hydroxylase	synaptic vesicle amine transport	Biological process	-
ENPEP	2028	glutamyl aminopeptidase (aminopeptidase A)	apical part of cell	Cellular component	-
RAC1	5879	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	bone resorption	Biological process	-
CTTNBP2NL	55917	CTTNBP2 N-terminal like	negative regulation of transmembrane transport	Biological process	24218568
POLR3GL	84265	polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like	innate immune response	Biological process	-
KRT5	3852	keratin 5, type II	extracellular exosome	Cellular component	19199708
EPHA2	1969	EPH receptor A2	protein kinase B signaling	Biological process	19573808
FANCA	2175	Fanconi anemia, complementation group A	protein binding	Molecular function	10627486
EHD3	30845	EH-domain containing 3	endocytic recycling	Biological process	17233914
FUT7	2529	fucosyltransferase 7 (alpha (1,3) fucosyltransferase)	fucosyltransferase activity	Molecular function	8207002
RUNX2	860	runt-related transcription factor 2	negative regulation of transcription, DNA-templated	Biological process	11965546
RAP1A	5906	RAP1A, member of RAS oncogene family	GTP binding	Molecular function	-
RPL27A	6157	ribosomal protein L27a	SRP-dependent cotranslational protein targeting to membrane	Biological process	-
SDCBP	6386	syndecan binding protein (syntenin)	protein binding	Molecular function	18256285
CYP2J2	1573	cytochrome P450, family 2, subfamily J, polypeptide 2	small molecule metabolic process	Biological process	-
RBPJ	3516	recombination signal binding protein for immunoglobulin kappa J region	auditory receptor cell fate commitment	Biological process	-
SRGAP2	23380	SLIT-ROBO Rho GTPase activating protein 2	postsynaptic membrane	Cellular component	-
RFX3	5991	regulatory factor X, 3 (influences HLA class II expression)	regulation of transcription from RNA polymerase II promoter	Biological process	-
MINK1	50488	misshapen-like kinase 1	protein kinase activity	Molecular function	10708748
PEX3	8504	peroxisomal biogenesis factor 3	intracellular membrane-bounded organelle	Cellular component	-
TJP1	7082	tight junction protein 1	response to magnetism	Biological process	-
NRP1	8829	neuropilin 1	semaphorin-plexin signaling pathway involved in neuron projection guidance	Biological process	-
HADHA	3030	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit	mitochondrial nucleoid	Cellular component	18063578
SPATA32	124783	spermatogenesis associated 32	actin binding	Molecular function	-
PLN	5350	phospholamban	enzyme inhibitor activity	Molecular function	12032137
HIP1R	9026	huntingtin interacting protein 1 related	protein binding	Molecular function	11889126
RABGGTA	5875	Rab geranylgeranyltransferase, alpha subunit	visual perception	Biological process	8380507
RFX3	5991	regulatory factor X, 3 (influences HLA class II expression)	regulation of transcription, DNA-templated	Biological process	-
WWP1	11059	WW domain containing E3 ubiquitin protein ligase 1	plasma membrane	Cellular component	-
PDE4D	5144	phosphodiesterase 4D, cAMP-specific	scaffold protein binding	Molecular function	15182229
PSMC1	5700	proteasome (prosome, macropain) 26S subunit, ATPase, 1	nuclear proteasome complex	Cellular component	-
BRCA1	672	breast cancer 1, early onset	positive regulation of transcription, DNA-templated	Biological process	10918303
DSCAM	1826	Down syndrome cell adhesion molecule	protein binding	Molecular function	19196994
RAB8A	4218	RAB8A, member RAS oncogene family	cytosol	Cellular component	-
SHOX2	6474	short stature homeobox 2	positive regulation of skeletal muscle fiber development	Biological process	-
RPS16	6217	ribosomal protein S16	RNA binding	Molecular function	17881366
TCF7L2	6934	transcription factor 7-like 2 (T-cell specific, HMG-box)	regulation of smooth muscle cell proliferation	Biological process	17122440
LIG1	3978	ligase I, DNA, ATP-dependent	Golgi apparatus	Cellular component	-
ATP2B2	491	ATPase, Ca++ transporting, plasma membrane 2	synapse organization	Biological process	-
PIK3C2A	5286	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha	phosphatidylinositol-3-phosphate biosynthetic process	Biological process	-
IL6ST	3572	interleukin 6 signal transducer	interleukin-6 binding	Molecular function	12829785
HLA-C	3107	major histocompatibility complex, class I, C	extracellular exosome	Cellular component	20458337
AP1M1	8907	adaptor-related protein complex 1, mu 1 subunit	antigen processing and presentation of exogenous peptide antigen via MHC class II	Biological process	-
HIST1H2AE	3012	histone cluster 1, H2ae	nucleosome	Cellular component	-
NUP35	129401	nucleoporin 35kDa	carbohydrate metabolic process	Biological process	-
SLC7A8	23428	solute carrier family 7 (amino acid transporter light chain, L system), member 8	antiporter activity	Molecular function	-
STAT5A	6776	signal transducer and activator of transcription 5A	lactation	Biological process	-
MTCH1	23787	mitochondrial carrier 1	transport	Biological process	-
HAMP	57817	hepcidin antimicrobial peptide	defense response to fungus	Biological process	-
SLC16A2	6567	solute carrier family 16, member 2 (thyroid hormone transporter)	thyroid hormone transport	Biological process	-
OR56A3	390083	olfactory receptor, family 56, subfamily A, member 3	integral component of membrane	Cellular component	-
MYH3	4621	myosin, heavy chain 3, skeletal muscle, embryonic	actin filament binding	Molecular function	16642020
RBP7	116362	retinol binding protein 7, cellular	transporter activity	Molecular function	-
OCRL	4952	oculocerebrorenal syndrome of Lowe	photoreceptor outer segment	Cellular component	22543976
SOX12	6666	SRY (sex determining region Y)-box 12	transcription regulatory region sequence-specific DNA binding	Molecular function	-
H2AFY2	55506	H2A histone family, member Y2	RNA polymerase II regulatory region sequence-specific DNA binding	Molecular function	23595991
ATMIN	23300	ATM interactor	cellular response to DNA damage stimulus	Biological process	-
LAMB1	3912	laminin, beta 1	extracellular matrix structural constituent	Molecular function	16289578
IRS1	3667	insulin receptor substrate 1	ciliary basal body	Cellular component	-
ACTR8	93973	ARP8 actin-related protein 8 homolog (yeast)	regulation of transcription, DNA-templated	Biological process	-
UBB	7314	ubiquitin B	DNA repair	Biological process	-
USP2	9099	ubiquitin specific peptidase 2	ubiquitin protein ligase binding	Molecular function	17290220
B3GNT2	10678	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	galactosyltransferase activity	Molecular function	-
PINK1	65018	PTEN induced putative kinase 1	positive regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	19880420
NOP58	51602	NOP58 ribonucleoprotein	snRNP protein import into nucleus	Biological process	10679015
ESR1	2099	estrogen receptor 1	positive regulation of cytosolic calcium ion concentration	Biological process	-
ABCC1	4363	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	small molecule metabolic process	Biological process	-
KIAA1109	84162	KIAA1109	regulation of cell growth	Biological process	17190194
ADRB1	153	adrenoceptor beta 1	dopamine binding	Molecular function	-
CHRM1	1128	cholinergic receptor, muscarinic 1	plasma membrane	Cellular component	-
PHF6	84295	PHD finger protein 6	DNA binding	Molecular function	-
SRMS	6725	src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites	innate immune response	Biological process	-
GPR176	11245	G protein-coupled receptor 176	G-protein coupled receptor signaling pathway	Biological process	-
AP5S1	55317	adaptor-related protein complex 5, sigma 1 subunit	late endosome membrane	Cellular component	-
BCOR	54880	BCL6 corepressor	negative regulation of histone H3-K4 methylation	Biological process	19578371
RNASE2	6036	ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)	lysosome	Cellular component	-
SLC6A14	11254	solute carrier family 6 (amino acid transporter), member 14	cellular amino acid metabolic process	Biological process	10446133
ZC3HAV1	56829	zinc finger CCCH-type, antiviral 1	defense response to virus	Biological process	-
SDCCAG3	10807	serologically defined colon cancer antigen 3	retrograde transport, endosome to plasma membrane	Biological process	25278552
PUS10	150962	pseudouridylate synthase 10	pseudouridine synthesis	Biological process	-
MKKS	8195	McKusick-Kaufman syndrome	striatum development	Biological process	-
MPST	4357	mercaptopyruvate sulfurtransferase	extracellular exosome	Cellular component	19056867
STX5	6811	syntaxin 5	Golgi membrane	Cellular component	-
ATF1	466	activating transcription factor 1	transcription from RNA polymerase II promoter	Biological process	-
HDAC4	9759	histone deacetylase 4	peptidyl-lysine deacetylation	Biological process	18614528
OR8S1	341568	olfactory receptor, family 8, subfamily S, member 1	olfactory receptor activity	Molecular function	-
OVCH2	341277	ovochymase 2 (gene/pseudogene)	extracellular region	Cellular component	-
TET1	80312	tet methylcytosine dioxygenase 1	gene expression	Biological process	-
HYOU1	10525	hypoxia up-regulated 1	response to ischemia	Biological process	-
ZNF398	57541	zinc finger protein 398	protein binding	Molecular function	21516116
ST3GAL2	6483	ST3 beta-galactoside alpha-2,3-sialyltransferase 2	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity	Molecular function	-
TICAM1	148022	toll-like receptor adaptor molecule 1	positive regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	12761501
CDCA7	83879	cell division cycle associated 7	transcription, DNA-templated	Biological process	-
NOS2	4843	nitric oxide synthase 2, inducible	negative regulation of blood pressure	Biological process	-
NCAPD3	23310	non-SMC condensin II complex, subunit D3	membrane	Cellular component	19946888
MED12L	116931	mediator complex subunit 12-like	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
GTF2H3	2967	general transcription factor IIH, polypeptide 3, 34kDa	DNA repair	Biological process	-
MAP7	9053	microtubule-associated protein 7	basolateral plasma membrane	Cellular component	-
RPS4X	6191	ribosomal protein S4, X-linked	viral life cycle	Biological process	-
PTEN	5728	phosphatase and tensin homolog	endothelial cell migration	Biological process	-
VAMP3	9341	vesicle-associated membrane protein 3	calcium ion-dependent exocytosis	Biological process	-
CCAR1	55749	cell division cycle and apoptosis regulator 1	cell cycle	Biological process	-
HUS1	3364	HUS1 checkpoint homolog (S. pombe)	nucleolus	Cellular component	-
ETNK2	55224	ethanolamine kinase 2	ethanolamine kinase activity	Molecular function	-
ARNT2	9915	aryl-hydrocarbon receptor nuclear translocator 2	transcription factor complex	Cellular component	-
KRR1	11103	KRR1, small subunit (SSU) processome component, homolog (yeast)	small-subunit processome	Cellular component	-
SORBS2	8470	sorbin and SH3 domain containing 2	nucleus	Cellular component	9211900
HIP1	3092	huntingtin interacting protein 1	clathrin-mediated endocytosis	Biological process	-
MLST8	64223	MTOR associated protein, LST8 homolog (S. cerevisiae)	cell cycle arrest	Biological process	-
STON2	85439	stonin 2	regulation of endocytosis	Biological process	14726597
IGHG3	3502	immunoglobulin heavy constant gamma 3 (G3m marker)	innate immune response	Biological process	-
CFHR3	10878	complement factor H-related 3	extracellular space	Cellular component	8428964
SHROOM2	357	shroom family member 2	protein binding	Molecular function	17474147
BCL2	596	B-cell CLL/lymphoma 2	axon regeneration	Biological process	-
OR10H1	26539	olfactory receptor, family 10, subfamily H, member 1	G-protein coupled receptor signaling pathway	Biological process	-
SOX9	6662	SRY (sex determining region Y)-box 9	protein kinase B signaling	Biological process	-
ST6GALNAC4	27090	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4	(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity	Molecular function	-
PLEKHA5	54477	pleckstrin homology domain containing, family A member 5	phosphatidylinositol-3,5-bisphosphate binding	Molecular function	-
RORB	6096	RAR-related orphan receptor B	gene expression	Biological process	-
TGFBR1	7046	transforming growth factor, beta receptor 1	wound healing	Biological process	9759503
SERPINE1	5054	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	negative regulation of blood coagulation	Biological process	1695900
CXCL12	6387	chemokine (C-X-C motif) ligand 12	cell chemotaxis	Biological process	18308860
GSK3A	2931	glycogen synthase kinase 3 alpha	positive regulation of heart contraction	Biological process	-
KDM1B	221656	lysine (K)-specific demethylase 1B	nucleoplasm	Cellular component	-
MBD5	55777	methyl-CpG binding domain protein 5	regulation of multicellular organism growth	Biological process	-
TAGLN	6876	transgelin	epithelial cell differentiation	Biological process	21492153
TAL1	6886	T-cell acute lymphocytic leukemia 1	regulation of mast cell differentiation	Biological process	-
TRO	7216	trophinin	integral component of plasma membrane	Cellular component	7758945
FSHR	2492	follicle stimulating hormone receptor	uterus development	Biological process	-
IFITM2	10581	interferon induced transmembrane protein 2	type I interferon signaling pathway	Biological process	-
HCFC1	3054	host cell factor C1	histone acetyltransferase activity (H4-K5 specific)	Molecular function	20018852
PPARA	5465	peroxisome proliferator-activated receptor alpha	MDM2/MDM4 family protein binding	Molecular function	-
PCSK5	5125	proprotein convertase subtilisin/kexin type 5	cytokine biosynthetic process	Biological process	8940009
RPS29	6235	ribosomal protein S29	viral process	Biological process	-
SP1	6667	Sp1 transcription factor	positive regulation of transcription, DNA-templated	Biological process	12771217
CAPN3	825	calpain 3, (p94)	Z disc	Cellular component	-
AXIN1	8312	axin 1	positive regulation of protein phosphorylation	Biological process	9601641
TMEM185B	79134	transmembrane protein 185B	integral component of membrane	Cellular component	-
CECR2	27443	cat eye syndrome chromosome region, candidate 2	nuclear euchromatin	Cellular component	-
PID1	55022	phosphotyrosine interaction domain containing 1	regulation of mitochondrial fusion	Biological process	20165904
TRIP12	9320	thyroid hormone receptor interactor 12	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	19028681
EPX	8288	eosinophil peroxidase	response to oxidative stress	Biological process	-
NUP35	129401	nucleoporin 35kDa	transmembrane transport	Biological process	-
PDPK1	5170	3-phosphoinositide dependent protein kinase 1	innate immune response	Biological process	-
CRTC1	23373	CREB regulated transcription coactivator 1	protein binding	Molecular function	14506290
BDKRB1	623	bradykinin receptor B1	positive regulation of leukocyte migration	Biological process	-
PIWIL1	9271	piwi-like RNA-mediated gene silencing 1	piRNA metabolic process	Biological process	-
IPO5	3843	importin 5	nuclear membrane	Cellular component	-
STXBP4	252983	syntaxin binding protein 4	extracellular exosome	Cellular component	19056867
AMHR2	269	anti-Mullerian hormone receptor, type II	protein binding	Molecular function	22939624
OR2T33	391195	olfactory receptor, family 2, subfamily T, member 33	olfactory receptor activity	Molecular function	-
MAF1	84232	MAF1 homolog (S. cerevisiae)	nucleolus	Cellular component	-
APIP	51074	APAF1 interacting protein	regulation of ERK1 and ERK2 cascade	Biological process	-
LRAT	9227	lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)	perinuclear region of cytoplasm	Cellular component	-
AURKA	6790	aurora kinase A	negative regulation of spindle checkpoint	Biological process	-
STT3B	201595	STT3B, subunit of the oligosaccharyltransferase complex (catalytic)	co-translational protein modification	Biological process	19167329
TRDMT1	1787	tRNA aspartic acid methyltransferase 1	DNA (cytosine-5-)-methyltransferase activity	Molecular function	9425235
AKR1B1	231	aldo-keto reductase family 1, member B1 (aldose reductase)	electron carrier activity	Molecular function	2112546
WNT4	54361	wingless-type MMTV integration site family, member 4	positive regulation of canonical Wnt signaling pathway	Biological process	16959810
PKD1	5310	polycystic kidney disease 1 (autosomal dominant)	peptidyl-serine phosphorylation	Biological process	-
WNT7B	7477	wingless-type MMTV integration site family, member 7B	proteinaceous extracellular matrix	Cellular component	-
EDN3	1908	endothelin 3	receptor binding	Molecular function	8298278
NT5C1A	84618	5'-nucleotidase, cytosolic IA	purine nucleobase metabolic process	Biological process	-
IFI16	3428	interferon, gamma-inducible protein 16	positive regulation of transcription from RNA polymerase II promoter	Biological process	21575908
TEK	7010	TEK tyrosine kinase, endothelial	cell-cell signaling	Biological process	8980225
GBA2	57704	glucosidase, beta (bile acid) 2	sphingolipid metabolic process	Biological process	-
RNF138	51444	ring finger protein 138, E3 ubiquitin protein ligase	nucleus	Cellular component	21630459
CHP1	11261	calcineurin-like EF-hand protein 1	membrane organization	Biological process	-
WHSC1	7468	Wolf-Hirschhorn syndrome candidate 1	atrial septum primum morphogenesis	Biological process	-
RYR3	6263	ryanodine receptor 3	integral component of membrane	Cellular component	-
PPIF	10105	peptidylprolyl isomerase F	negative regulation of oxidative phosphorylation uncoupler activity	Biological process	-
CROT	54677	carnitine O-octanoyltransferase	medium-chain fatty acid metabolic process	Biological process	10486279
MT3	4504	metallothionein 3	activation of protein kinase B activity	Biological process	18295594
TRAF3IP2	10758	TRAF3 interacting protein 2	intracellular signal transduction	Biological process	10962033
FOXC2	2303	forkhead box C2	paraxial mesodermal cell fate commitment	Biological process	-
CPXM1	56265	carboxypeptidase X (M14 family), member 1	extracellular space	Cellular component	-
MSL2	55167	male-specific lethal 2 homolog (Drosophila)	chromatin organization	Biological process	-
CPOX	1371	coproporphyrinogen oxidase	mitochondrial intermembrane space	Cellular component	-
HMGCS1	3157	3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)	isomerase activity	Molecular function	-
EWSR1	2130	EWS RNA-binding protein 1	transcription, DNA-templated	Biological process	-
CALR	811	calreticulin	unfolded protein binding	Molecular function	15474971
TNFRSF4	7293	tumor necrosis factor receptor superfamily, member 4	integral component of plasma membrane	Cellular component	7510240
GATA4	2626	GATA binding protein 4	atrioventricular canal development	Biological process	-
SOX17	64321	SRY (sex determining region Y)-box 17	transcription regulatory region DNA binding	Molecular function	-
CYFIP2	26999	cytoplasmic FMR1 interacting protein 2	activation of cysteine-type endopeptidase activity	Biological process	18387192
LMF2	91289	lipase maturation factor 2	integral component of membrane	Cellular component	-
CYP2F1	1572	cytochrome P450, family 2, subfamily F, polypeptide 1	arachidonic acid epoxygenase activity	Molecular function	-
LILRB1	10859	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	cytoplasm	Cellular component	15585844
STEAP4	79689	STEAP family member 4	Golgi membrane	Cellular component	-
HOXB5	3215	homeobox B5	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
MYH7	4625	myosin, heavy chain 7, cardiac muscle, beta	stress fiber	Cellular component	-
UHRF1	29128	ubiquitin-like with PHD and ring finger domains 1	ligase activity	Molecular function	-
PKD1	5310	polycystic kidney disease 1 (autosomal dominant)	metanephric proximal tubule development	Biological process	11891195
STPG1	90529	sperm-tail PG-rich repeat containing 1	cytoplasm	Cellular component	-
ADAL	161823	adenosine deaminase-like	drug metabolic process	Biological process	-
C1orf56	54964	chromosome 1 open reading frame 56	cytoplasm	Cellular component	-
ME3	10873	malic enzyme 3, NADP(+)-dependent, mitochondrial	cofactor binding	Molecular function	7818469
THY1	7070	Thy-1 cell surface antigen	protein binding	Molecular function	7513706
KIF18A	81930	kinesin family member 18A	ruffle	Cellular component	17006958
FGFR2	2263	fibroblast growth factor receptor 2	bone mineralization	Biological process	-
MSTN	2660	myostatin	response to testosterone	Biological process	-
PTPN23	25930	protein tyrosine phosphatase, non-receptor type 23	early endosome	Cellular component	21757351
ZNF830	91603	zinc finger protein 830	intestinal epithelial structure maintenance	Biological process	-
MRPL2	51069	mitochondrial ribosomal protein L2	mitochondrial translational initiation	Biological process	-
NLGN1	22871	neuroligin 1	neuronal signal transduction	Biological process	15797875
PLSCR1	5359	phospholipid scramblase 1	regulation of Fc receptor mediated stimulatory signaling pathway	Biological process	-
GNL2	29889	guanine nucleotide binding protein-like 2 (nucleolar)	ribosome biogenesis	Biological process	-
RPL37A	6168	ribosomal protein L37a	translational elongation	Biological process	-
PRSS23	11098	protease, serine, 23	proteolysis	Biological process	-
POLD4	57804	polymerase (DNA-directed), delta 4, accessory subunit	telomere maintenance	Biological process	-
PHOX2B	8929	paired-like homeobox 2b	positive regulation of neuron differentiation	Biological process	-
LPO	4025	lactoperoxidase	detection of chemical stimulus involved in sensory perception of bitter taste	Biological process	24248522
ULK1	8408	unc-51 like autophagy activating kinase 1	positive regulation of macroautophagy	Biological process	22354037
COQ3	51805	coenzyme Q3 methyltransferase	mitochondrion	Cellular component	10777520
NKIRAS2	28511	NFKB inhibitor interacting Ras-like 2	GTPase activity	Molecular function	10657303
CATSPER3	347732	cation channel, sperm associated 3	sperm capacitation	Biological process	-
NDC1	55706	NDC1 transmembrane nucleoporin	synapsis	Biological process	-
EXOG	9941	endo/exonuclease (5'-3'), endonuclease G-like	nucleic acid binding	Molecular function	-
CTSH	1512	cathepsin H	protein complex binding	Molecular function	-
SCNN1A	6337	sodium channel, non voltage gated 1 alpha subunit	cortical actin cytoskeleton	Cellular component	-
KCNS1	3787	potassium voltage-gated channel, modifier subfamily S, member 1	protein homooligomerization	Biological process	-
HNRNPR	10236	heterogeneous nuclear ribonucleoprotein R	nucleotide binding	Molecular function	-
SRF	6722	serum response factor (c-fos serum response element-binding transcription factor)	bicellular tight junction assembly	Biological process	-
RNASE11	122651	ribonuclease, RNase A family, 11 (non-active)	RNA phosphodiester bond hydrolysis	Biological process	-
CRNKL1	51340	crooked neck pre-mRNA splicing factor 1	mRNA splicing, via spliceosome	Biological process	11991638
CTSD	1509	cathepsin D	membrane raft	Cellular component	25204797
RPS28	6234	ribosomal protein S28	translational termination	Biological process	-
KBTBD13	390594	kelch repeat and BTB (POZ) domain containing 13	cytoplasm	Cellular component	-
ARPC5	10092	actin related protein 2/3 complex, subunit 5, 16kDa	actin filament binding	Molecular function	11741539
RPS6KA1	6195	ribosomal protein S6 kinase, 90kDa, polypeptide 1	synaptic transmission	Biological process	-
TNK1	8711	tyrosine kinase, non-receptor, 1	protein tyrosine kinase activity	Molecular function	10873601
RECQL5	9400	RecQ protein-like 5	DNA repair	Biological process	22973052
RNASE9	390443	ribonuclease, RNase A family, 9 (non-active)	endonuclease activity	Molecular function	-
TARBP1	6894	TAR (HIV-1) RNA binding protein 1	RNA methyltransferase activity	Molecular function	-
NANOG	79923	Nanog homeobox	transcription, DNA-templated	Biological process	-
ABCA12	26154	ATP-binding cassette, sub-family A (ABC1), member 12	secretion by cell	Biological process	16007253
AMFR	267	autocrine motility factor receptor, E3 ubiquitin protein ligase	movement of cell or subcellular component	Biological process	1649192
STX8	9482	syntaxin 8	transport	Biological process	10198254
PRKD3	23683	protein kinase D3	protein phosphorylation	Biological process	-
DHDDS	79947	dehydrodolichyl diphosphate synthase	endoplasmic reticulum membrane	Cellular component	-
FGFR1	2260	fibroblast growth factor receptor 1	midbrain development	Biological process	-
WNT7B	7477	wingless-type MMTV integration site family, member 7B	outer medullary collecting duct development	Biological process	-
NUP153	9972	nucleoporin 153kDa	cellular response to heat	Biological process	-
STAT5A	6776	signal transducer and activator of transcription 5A	positive regulation of inflammatory response	Biological process	-
CFAP20	29105	cilia and flagella associated protein 20	microtubule	Cellular component	-
PLXNA4	91584	plexin A4	postganglionic parasympathetic fiber development	Biological process	-
SLC1A5	6510	solute carrier family 1 (neutral amino acid transporter), member 5	melanosome	Cellular component	-
GIPR	2696	gastric inhibitory polypeptide receptor	response to axon injury	Biological process	-
CASP8	841	caspase 8, apoptosis-related cysteine peptidase	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	Biological process	-
ST6GALNAC6	30815	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6	sialyltransferase activity	Molecular function	12668675
FAM160A2	84067	family with sequence similarity 160, member A2	FHF complex	Cellular component	18799622
XRCC4	7518	X-ray repair complementing defective repair in Chinese hamster cells 4	negative regulation of neuron apoptotic process	Biological process	-
CDK5R1	8851	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	embryo development	Biological process	-
ANP32A	8125	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	poly(A) RNA binding	Molecular function	22681889
ERCC3	2071	excision repair cross-complementation group 3	transcription-coupled nucleotide-excision repair	Biological process	-
TMEM25	84866	transmembrane protein 25	plasma membrane	Cellular component	-
SPACA3	124912	sperm acrosome associated 3	acrosomal membrane	Cellular component	-
STAT4	6775	signal transducer and activator of transcription 4	JAK-STAT cascade	Biological process	9284918
SF3B4	10262	splicing factor 3b, subunit 4, 49kDa	RNA splicing, via transesterification reactions	Biological process	7958871
WWP2	11060	WW domain containing E3 ubiquitin protein ligase 2	protein autoubiquitination	Biological process	24105792
ESRRB	2103	estrogen-related receptor beta	nucleus	Cellular component	-
DAPP1	27071	dual adaptor of phosphotyrosine and 3-phosphoinositides	protein dephosphorylation	Biological process	10432293
ZNF805	390980	zinc finger protein 805	DNA binding	Molecular function	-
NAGPA	51172	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity	Molecular function	-
ATG2B	55102	autophagy related 2B	lipid particle	Cellular component	-
KCNJ1	3758	potassium channel, inwardly rectifying subfamily J, member 1	post-embryonic development	Biological process	-
RUVBL1	8607	RuvB-like AAA ATPase 1	MLL1 complex	Cellular component	15960975
SOX11	6664	SRY (sex determining region Y)-box 11	positive regulation of lens epithelial cell proliferation	Biological process	-
ADIPOR1	51094	adiponectin receptor 1	identical protein binding	Molecular function	-
DLX4	1748	distal-less homeobox 4	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	11909945
TCTN2	79867	tectonic family member 2	cilium morphogenesis	Biological process	-
ADCYAP1	116	adenylate cyclase activating polypeptide 1 (pituitary)	regulation of oligodendrocyte progenitor proliferation	Biological process	-
APBB1	322	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	positive regulation of transcription, DNA-templated	Biological process	19343227
FOSL2	2355	FOS-like antigen 2	double-stranded DNA binding	Molecular function	-
CASP2	835	caspase 2, apoptosis-related cysteine peptidase	positive regulation of apoptotic process	Biological process	10980123
NF1	4763	neurofibromin 1	regulation of synaptic transmission, GABAergic	Biological process	-
NOD2	64127	nucleotide-binding oligomerization domain containing 2	basolateral plasma membrane	Cellular component	-
ACTBL2	345651	actin, beta-like 2	molecular_function	Molecular function	-
SLC38A2	54407	solute carrier family 38, member 2	sodium ion transport	Biological process	-
FUCA2	2519	fucosidase, alpha-L- 2, plasma	fucose metabolic process	Biological process	19666478
CP	1356	ceruloplasmin (ferroxidase)	blood microparticle	Cellular component	22516433
STON2	85439	stonin 2	clathrin-coated vesicle	Cellular component	-
PPP2R3C	55012	protein phosphatase 2, regulatory subunit B'', gamma	positive regulation of B cell differentiation	Biological process	-
ACADL	33	acyl-CoA dehydrogenase, long chain	flavin adenine dinucleotide binding	Molecular function	-
TMED7	51014	transmembrane emp24 protein transport domain containing 7	endoplasmic reticulum-Golgi intermediate compartment membrane	Cellular component	-
ANKFY1	51479	ankyrin repeat and FYVE domain containing 1	endosome membrane	Cellular component	-
BSG	682	basigin (Ok blood group)	Golgi membrane	Cellular component	-
STMN1	3925	stathmin 1	brain development	Biological process	-
VPS52	6293	vacuolar protein sorting 52 homolog (S. cerevisiae)	syntaxin binding	Molecular function	15878329
MAOA	4128	monoamine oxidase A	oxidation-reduction process	Biological process	-
TCAF2	285966	TRPM8 channel-associated factor 2	positive regulation of protein targeting to membrane	Biological process	25559186
ABHD6	57406	abhydrolase domain containing 6	regulation of endocannabinoid signaling pathway	Biological process	-
TSPO	706	translocator protein (18kDa)	chloride transport	Biological process	-
AKR7A2	8574	aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)	electron carrier activity	Molecular function	9576847
PAX8	7849	paired box 8	mesenchymal to epithelial transition involved in metanephros morphogenesis	Biological process	8861958
APLP2	334	amyloid beta (A4) precursor-like protein 2	membrane	Cellular component	19946888
GRIN1	2902	glutamate receptor, ionotropic, N-methyl D-aspartate 1	cell junction	Cellular component	-
GNA13	10672	guanine nucleotide binding protein (G protein), alpha 13	signal transducer activity	Molecular function	-
SCN3A	6328	sodium channel, voltage gated, type III alpha subunit	voltage-gated sodium channel complex	Cellular component	-
LCE4A	199834	late cornified envelope 4A	protein binding	Molecular function	25416956
RAB38	23682	RAB38, member RAS oncogene family	endosome to melanosome transport	Biological process	22511774
PDE10A	10846	phosphodiesterase 10A	3',5'-cyclic-nucleotide phosphodiesterase activity	Molecular function	10373451
LCN10	414332	lipocalin 10	extracellular region	Cellular component	-
SYT14	255928	synaptotagmin XIV	calcium ion-dependent exocytosis of neurotransmitter	Biological process	-
ZNF578	147660	zinc finger protein 578	cytoplasm	Cellular component	-
SBDS	51119	Shwachman-Bodian-Diamond syndrome	ribosome binding	Molecular function	21536732
CDK13	8621	cyclin-dependent kinase 13	protein kinase activity	Molecular function	1731328
STAT5A	6776	signal transducer and activator of transcription 5A	positive regulation of activated T cell proliferation	Biological process	-
STARD3	10948	StAR-related lipid transfer (START) domain containing 3	cytoplasm	Cellular component	9139840
CXCR3	2833	chemokine (C-X-C motif) receptor 3	positive regulation of cell proliferation	Biological process	12782716
SETX	23064	senataxin	nucleolus	Cellular component	-
NEDD4	4734	neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase	regulation of ion transmembrane transport	Biological process	17289006
ADRA2A	150	adrenoceptor alpha 2A	protein heterodimerization activity	Molecular function	-
TUBB8	347688	tubulin, beta 8 class VIII	microtubule	Cellular component	-
ZNF655	79027	zinc finger protein 655	transcription, DNA-templated	Biological process	-
IQGAP2	10788	IQ motif containing GTPase activating protein 2	cytoplasm	Cellular component	12515716
XBP1	7494	X-box binding protein 1	positive regulation of fat cell differentiation	Biological process	-
CYP11B1	1584	cytochrome P450, family 11, subfamily B, polypeptide 1	aldosterone biosynthetic process	Biological process	19342457
EIF4A3	9775	eukaryotic translation initiation factor 4A3	rRNA processing	Biological process	-
FOXP1	27086	forkhead box P1	nucleus	Cellular component	25027557
SFRP2	6423	secreted frizzled-related protein 2	positive regulation of endopeptidase activity	Biological process	-
RP2	6102	retinitis pigmentosa 2 (X-linked recessive)	protein folding	Biological process	9697692
POLL	27343	polymerase (DNA directed), lambda	DNA-directed DNA polymerase activity	Molecular function	10982892
ENPP7	339221	ectonucleotide pyrophosphatase/phosphodiesterase 7	sphingomyelin phosphodiesterase activity	Molecular function	12671034
E2F5	1875	E2F transcription factor 5, p130-binding	transcription initiation from RNA polymerase II promoter	Biological process	-
USP19	10869	ubiquitin specific peptidase 19	negative regulation of skeletal muscle tissue development	Biological process	-
ASB4	51666	ankyrin repeat and SOCS box containing 4	Cul2-RING ubiquitin ligase complex	Cellular component	17636018
GRIN2A	2903	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	synaptic vesicle	Cellular component	-
MED10	84246	mediator complex subunit 10	nucleoplasm	Cellular component	-
COL16A1	1307	collagen, type XVI, alpha 1	extracellular matrix disassembly	Biological process	-
NFKB2	4791	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
EPHA1	2041	EPH receptor A1	protein autophosphorylation	Biological process	19118217
DNAH3	55567	dynein, axonemal, heavy chain 3	microtubule-based movement	Biological process	-
TBX2	6909	T-box 2	DNA binding	Molecular function	8530034
SLC7A3	84889	solute carrier family 7 (cationic amino acid transporter, y+ system), member 3	L-ornithine transmembrane transporter activity	Molecular function	-
CCR1	1230	chemokine (C-C motif) receptor 1	positive regulation of cell migration	Biological process	24056371
RACGAP1	29127	Rac GTPase activating protein 1	blood coagulation	Biological process	-
HECW1	23072	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	-
EHD4	30844	EH-domain containing 4	GTP binding	Molecular function	-
MOCOS	55034	molybdenum cofactor sulfurase	cellular_component	Cellular component	-
ATP6V0A4	50617	ATPase, H+ transporting, lysosomal V0 subunit a4	endosome membrane	Cellular component	-
MAPK3	5595	mitogen-activated protein kinase 3	epidermal growth factor receptor signaling pathway	Biological process	-
LYST	1130	lysosomal trafficking regulator	endosome to lysosome transport via multivesicular body sorting pathway	Biological process	9606205
SMARCAD1	56916	SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1	heterochromatin	Cellular component	-
JMJD1C	221037	jumonji domain containing 1C	dioxygenase activity	Molecular function	-
ADCY3	109	adenylate cyclase 3	renal water homeostasis	Biological process	-
BGLAP	632	bone gamma-carboxyglutamate (gla) protein	response to zinc ion	Biological process	-
RYK	6259	receptor-like tyrosine kinase	protein tyrosine kinase activity	Molecular function	10454588
CCDC184	387856	coiled-coil domain containing 184	cytoplasm	Cellular component	-
LYZL4	131375	lysozyme-like 4	lysozyme activity	Molecular function	-
GSTA4	2941	glutathione S-transferase alpha 4	glutathione metabolic process	Biological process	10329152
TXNL4A	10907	thioredoxin-like 4A	U4/U6 x U5 tri-snRNP complex	Cellular component	-
EDNRB	1910	endothelin receptor type B	positive regulation of cytosolic calcium ion concentration	Biological process	-
HIST1H3I	8354	histone cluster 1, H3i	extracellular region	Cellular component	-
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	nitric-oxide synthase binding	Molecular function	-
GFAP	2670	glial fibrillary acidic protein	response to wounding	Biological process	-
TIMM21	29090	translocase of inner mitochondrial membrane 21 homolog (yeast)	mitochondrial inner membrane presequence translocase complex	Cellular component	23260140
KCNA1	3736	potassium channel, voltage gated shaker related subfamily A, member 1	cellular response to magnesium ion	Biological process	-
SPRY2	10253	sprouty homolog 2 (Drosophila)	microtubule cytoskeleton	Cellular component	-
NCOA1	8648	nuclear receptor coactivator 1	RNA polymerase II transcription coactivator activity	Molecular function	15774904
ZFYVE16	9765	zinc finger, FYVE domain containing 16	cytoplasm	Cellular component	-
AKR1A1	10327	aldo-keto reductase family 1, member A1 (aldehyde reductase)	D-glucuronate catabolic process	Biological process	-
SERPING1	710	serpin peptidase inhibitor, clade G (C1 inhibitor), member 1	platelet activation	Biological process	-
STRADB	55437	STE20-related kinase adaptor beta	cytosol	Cellular component	-
DIAPH1	1729	diaphanous-related formin 1	receptor binding	Molecular function	9360932
METTL18	92342	methyltransferase like 18	methyltransferase activity	Molecular function	-
PRKCA	5578	protein kinase C, alpha	induction of positive chemotaxis	Biological process	-
CEP290	80184	centrosomal protein 290kDa	regulation of cAMP metabolic process	Biological process	-
TM9SF3	56889	transmembrane 9 superfamily member 3	integral component of membrane	Cellular component	-
DSC1	1823	desmocollin 1	integral component of membrane	Cellular component	-
IRF1	3659	interferon regulatory factor 1	nucleoplasm	Cellular component	-
SLC25A46	91137	solute carrier family 25, member 46	transport	Biological process	-
APOBEC3A	200315	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A	deoxycytidine deaminase activity	Molecular function	22457529
DGKD	8527	diacylglycerol kinase, delta 130kDa	protein transport	Biological process	-
CAMK1G	57172	calcium/calmodulin-dependent protein kinase IG	neuron projection	Cellular component	-
IMPA1	3612	inositol(myo)-1(or 4)-monophosphatase 1	protein binding	Molecular function	25416956
HIST1H2AA	221613	histone cluster 1, H2aa	DNA binding	Molecular function	-
KRTAP4-4	84616	keratin associated protein 4-4	keratin filament	Cellular component	-
ELOVL5	60481	ELOVL fatty acid elongase 5	fatty acid elongation, monounsaturated fatty acid	Biological process	20427700
SLC2A3	6515	solute carrier family 2 (facilitated glucose transporter), member 3	L-ascorbic acid metabolic process	Biological process	-
DUOXA1	90527	dual oxidase maturation factor 1	integral component of membrane	Cellular component	-
MC3R	4159	melanocortin 3 receptor	adenylate cyclase-modulating G-protein coupled receptor signaling pathway	Biological process	-
POLR2H	5437	polymerase (RNA) II (DNA directed) polypeptide H	piRNA metabolic process	Biological process	-
PYURF	100996939	PIGY upstream reading frame	protein binding	Molecular function	16162815
POLG2	11232	polymerase (DNA directed), gamma 2, accessory subunit	DNA-directed DNA polymerase activity	Molecular function	-
QPCTL	54814	glutaminyl-peptide cyclotransferase-like	membrane	Cellular component	19946888
CLPS	1208	colipase, pancreatic	enzyme activator activity	Molecular function	-
DCP1B	196513	decapping mRNA 1B	nucleus	Cellular component	-
ADSL	158	adenylosuccinate lyase	aerobic respiration	Biological process	-
EMB	133418	embigin	synapse	Cellular component	-
RAF1	5894	Raf-1 proto-oncogene, serine/threonine kinase	insulin receptor signaling pathway	Biological process	-
RACGAP1	29127	Rac GTPase activating protein 1	centralspindlin complex	Cellular component	11782313
SOX12	6666	SRY (sex determining region Y)-box 12	protein-DNA complex	Cellular component	-
SLC16A1	6566	solute carrier family 16 (monocarboxylate transporter), member 1	extracellular exosome	Cellular component	20458337
TRAF2	7186	TNF receptor-associated factor 2	IRE1-TRAF2-ASK1 complex	Cellular component	23000344
RPL29	6159	ribosomal protein L29	translational elongation	Biological process	-
MOGAT2	80168	monoacylglycerol O-acyltransferase 2	acetyltransferase activity	Molecular function	-
GOLT1A	127845	golgi transport 1A	vesicle-mediated transport	Biological process	-
PDIA3	2923	protein disulfide isomerase family A, member 3	protein binding	Molecular function	15896298
RBM5	10181	RNA binding motif protein 5	RNA processing	Biological process	10352938
IKBIP	121457	IKBKB interacting protein	endoplasmic reticulum membrane	Cellular component	-
C11orf63	79864	chromosome 11 open reading frame 63	brain development	Biological process	-
CDC25A	993	cell division cycle 25A	peptidyl-tyrosine dephosphorylation	Biological process	-
FGF8	2253	fibroblast growth factor 8 (androgen-induced)	MAPK cascade	Biological process	-
PARK7	11315	parkinson protein 7	positive regulation of superoxide dismutase activity	Biological process	24567322
DEK	7913	DEK proto-oncogene	regulation of transcription from RNA polymerase II promoter	Biological process	9050861
SFXN5	94097	sideroflexin 5	integral component of membrane	Cellular component	-
MT1M	4499	metallothionein 1M	perinuclear region of cytoplasm	Cellular component	-
RPS6KA4	8986	ribosomal protein S6 kinase, 90kDa, polypeptide 4	ATP binding	Molecular function	9792677
PREB	10113	prolactin regulatory element binding	IRE1-mediated unfolded protein response	Biological process	-
TARDBP	23435	TAR DNA binding protein	nucleus	Cellular component	-
PQBP1	10084	polyglutamine binding protein 1	neuronal ribonucleoprotein granule	Cellular component	-
SMC2	10592	structural maintenance of chromosomes 2	cytosol	Cellular component	-
PIN4	5303	peptidylprolyl cis/trans isomerase, NIMA-interacting 4	bent DNA binding	Molecular function	12144781
CHCHD1	118487	coiled-coil-helix-coiled-coil-helix domain containing 1	mitochondrial translational elongation	Biological process	-
SCGN	10590	secretagogin, EF-hand calcium binding protein	extracellular region	Cellular component	-
DGAT2L6	347516	diacylglycerol O-acyltransferase 2-like 6	transferase activity, transferring acyl groups other than amino-acyl groups	Molecular function	-
TCEB2	6923	transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)	cytosol	Cellular component	-
POLR1A	25885	polymerase (RNA) I polypeptide A, 194kDa	transcription initiation from RNA polymerase I promoter	Biological process	-
HDAC8	55869	histone deacetylase 8	metal ion binding	Molecular function	-
SIX3	6496	SIX homeobox 3	telencephalon development	Biological process	-
ITIH4	3700	inter-alpha-trypsin inhibitor heavy chain family, member 4	protein binding	Molecular function	16271702
LYZ	4069	lysozyme	identical protein binding	Molecular function	23353684
PGLYRP1	8993	peptidoglycan recognition protein 1	detection of bacterium	Biological process	11461926
PHOX2B	8929	paired-like homeobox 2b	inner ear development	Biological process	-
DAB1	1600	Dab, reelin signal transducer, homolog 1 (Drosophila)	negative regulation of astrocyte differentiation	Biological process	-
SLC25A26	115286	solute carrier family 25 (S-adenosylmethionine carrier), member 26	S-adenosyl-L-methionine transmembrane transport	Biological process	14674884
CLC	1178	Charcot-Leyden crystal galectin	protein binding	Molecular function	11834744
CXCL2	2920	chemokine (C-X-C motif) ligand 2	response to molecule of bacterial origin	Biological process	19912257
PRRX1	5396	paired related homeobox 1	embryonic cranial skeleton morphogenesis	Biological process	-
BIRC7	79444	baculoviral IAP repeat containing 7	regulation of cell proliferation	Biological process	21617971
CDKN2A	1029	cyclin-dependent kinase inhibitor 2A	NF-kappaB binding	Molecular function	10353611
FBP2	8789	fructose-1,6-bisphosphatase 2	cell junction	Cellular component	-
LMCD1	29995	LIM and cysteine-rich domains 1	nucleus	Cellular component	-
SLC2A6	11182	solute carrier family 2 (facilitated glucose transporter), member 6	membrane	Cellular component	10970791
ITLN1	55600	intelectin 1 (galactofuranose binding)	positive regulation of protein phosphorylation	Biological process	16531507
HMGB4	127540	high mobility group box 4	nucleus	Cellular component	21630459
SPG20	23111	spastic paraplegia 20 (Troyer syndrome)	cell division	Biological process	20719964
ALPK1	80216	alpha-kinase 1	activation of mitophagy in response to mitochondrial depolarization	Biological process	22020285
KRT1	3848	keratin 1, type II	extracellular exosome	Cellular component	11487543
SLC30A8	169026	solute carrier family 30 (zinc transporter), member 8	cellular zinc ion homeostasis	Biological process	-
OR5P2	120065	olfactory receptor, family 5, subfamily P, member 2	integral component of plasma membrane	Cellular component	-
SGMS2	166929	sphingomyelin synthase 2	kinase activity	Molecular function	-
PRKAR1A	5573	protein kinase, cAMP-dependent, regulatory, type I, alpha	neuromuscular junction	Cellular component	-
PTH2	113091	parathyroid hormone 2	extracellular region	Cellular component	-
IK	3550	IK cytokine, down-regulator of HLA II	nucleolus	Cellular component	-
KDM1A	23028	lysine (K)-specific demethylase 1A	sequence-specific DNA binding transcription factor activity	Molecular function	-
BIRC2	329	baculoviral IAP repeat containing 2	regulation of transcription, DNA-templated	Biological process	-
TMEM86A	144110	transmembrane protein 86A	integral component of membrane	Cellular component	-
CD34	947	CD34 molecule	basal plasma membrane	Cellular component	-
UCHL1	7345	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)	cysteine-type endopeptidase activity	Molecular function	8639624
GTPBP3	84705	GTP binding protein 3 (mitochondrial)	tRNA modification	Biological process	-
YWHAG	7532	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma	intrinsic apoptotic signaling pathway	Biological process	-
TGFB1	7040	transforming growth factor, beta 1	regulation of cartilage development	Biological process	-
PCSK9	255738	proprotein convertase subtilisin/kexin type 9	early endosome	Cellular component	17461796
HIST1H2BB	3018	histone cluster 1, H2bb	nucleosome	Cellular component	9439656
ZBTB17	7709	zinc finger and BTB domain containing 17	ectoderm development	Biological process	-
HHAT	55733	hedgehog acyltransferase	protein palmitoylation	Biological process	-
POLR2G	5436	polymerase (RNA) II (DNA directed) polypeptide G	DNA-directed RNA polymerase activity	Molecular function	-
KCNJ2	3759	potassium channel, inwardly rectifying subfamily J, member 2	cellular response to mechanical stimulus	Biological process	-
MYBL1	4603	v-myb avian myeloblastosis viral oncogene homolog-like 1	piRNA metabolic process	Biological process	-
PTPRN2	5799	protein tyrosine phosphatase, receptor type, N polypeptide 2	protein dephosphorylation	Biological process	8798755
ZNF511	118472	zinc finger protein 511	metal ion binding	Molecular function	-
NOS3	4846	nitric oxide synthase 3 (endothelial cell)	negative regulation of calcium ion transport	Biological process	-
BBS12	166379	Bardet-Biedl syndrome 12	photoreceptor cell maintenance	Biological process	-
SMARCE1	6605	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	metabolic process	Biological process	12192000
SLC22A2	6582	solute carrier family 22 (organic cation transporter), member 2	synaptic transmission	Biological process	-
EVI5	7813	ecotropic viral integration site 5	multicellular organismal development	Biological process	9618176
SPRN	503542	shadow of prion protein homolog (zebrafish)	protein import into nucleus	Biological process	-
IRAK1BP1	134728	interleukin-1 receptor-associated kinase 1 binding protein 1	transcription, DNA-templated	Biological process	-
ALKBH8	91801	alkB, alkylation repair homolog 8 (E. coli)	iron ion binding	Molecular function	-
NMT2	9397	N-myristoyltransferase 2	N-terminal peptidyl-glycine N-myristoylation	Biological process	25255805
ETV6	2120	ets variant 6	negative regulation of transcription from RNA polymerase II promoter	Biological process	10514502
CFB	629	complement factor B	serine-type endopeptidase activity	Molecular function	-
NUDT16	131870	nudix (nucleoside diphosphate linked moiety X)-type motif 16	positive regulation of double-strand break repair	Biological process	20385596
ANGPT2	285	angiopoietin 2	cell projection	Cellular component	-
USO1	8615	USO1 vesicle transport factor	transcytosis	Biological process	-
PPM1B	5495	protein phosphatase, Mg2+/Mn2+ dependent, 1B	N-terminal protein myristoylation	Biological process	-
ACTN4	81	actinin, alpha 4	protein binding	Molecular function	15619032
CUTC	51076	cutC copper transporter	copper ion homeostasis	Biological process	16182249
MAP3K7	6885	mitogen-activated protein kinase kinase kinase 7	MyD88-dependent toll-like receptor signaling pathway	Biological process	-
ZPBP	11055	zona pellucida binding protein	nucleus	Cellular component	21630459
CNTFR	1271	ciliary neurotrophic factor receptor	apical plasma membrane	Cellular component	21912637
PPP2R4	5524	protein phosphatase 2A activator, regulatory subunit 4	protein peptidyl-prolyl isomerization	Biological process	-
GTPBP2	54676	GTP binding protein 2	biological_process	Biological process	-
CSNK2A2	1459	casein kinase 2, alpha prime polypeptide	mitotic spindle checkpoint	Biological process	11704824
MLLT11	10962	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11	positive regulation of apoptotic process	Biological process	18852119
AMTN	401138	amelotin	basal lamina	Cellular component	16787391
KMT2E	55904	lysine (K)-specific methyltransferase 2E	transcription coactivator activity	Molecular function	-
RARA	5914	retinoic acid receptor, alpha	protein kinase B binding	Molecular function	16417524
CALR	811	calreticulin	poly(A) RNA binding	Molecular function	22658674
DBX1	120237	developing brain homeobox 1	nucleus	Cellular component	-
EBAG9	9166	estrogen receptor binding site associated, antigen, 9	plasma membrane	Cellular component	-
MAP1B	4131	microtubule-associated protein 1B	microtubule bundle formation	Biological process	-
CLEC5A	23601	C-type lectin domain family 5, member A	negative regulation of myeloid cell apoptotic process	Biological process	-
ARL4A	10124	ADP-ribosylation factor-like 4A	nucleus	Cellular component	10980193
NUP93	9688	nucleoporin 93kDa	nuclear pore	Cellular component	12802065
TAF9	6880	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa	protein heterodimerization activity	Molecular function	-
CD2AP	23607	CD2-associated protein	plasma membrane	Cellular component	-
INA	9118	internexin neuronal intermediate filament protein, alpha	extracellular space	Cellular component	22664934
RSAD2	91543	radical S-adenosyl methionine domain containing 2	response to virus	Biological process	21957124
JAK2	3717	Janus kinase 2	receptor binding	Molecular function	11201744
MYH10	4628	myosin, heavy chain 10, non-muscle	extracellular exosome	Cellular component	23533145
TOMM40	10452	translocase of outer mitochondrial membrane 40 homolog (yeast)	cytoplasm	Cellular component	-
WIPI1	55062	WD repeat domain, phosphoinositide interacting 1	protein localization to pre-autophagosomal structure	Biological process	-
BACE2	25825	beta-site APP-cleaving enzyme 2	endoplasmic reticulum	Cellular component	-
STX7	8417	syntaxin 7	extracellular exosome	Cellular component	20458337
AGPAT2	10555	1-acylglycerol-3-phosphate O-acyltransferase 2	endoplasmic reticulum membrane	Cellular component	-
RGS2	5997	regulator of G-protein signaling 2	negative regulation of phospholipase activity	Biological process	-
ZNF225	7768	zinc finger protein 225	DNA binding	Molecular function	-
PSMD9	5715	proteasome (prosome, macropain) 26S subunit, non-ATPase, 9	proteasome regulatory particle, base subcomplex	Cellular component	19490896
TDG	6996	thymine-DNA glycosylase	protein homodimerization activity	Molecular function	22327402
GSC	145258	goosecoid homeobox	signal transduction involved in regulation of gene expression	Biological process	-
PXT1	222659	peroxisomal, testis specific 1	spermatogenesis	Biological process	-
ATP7A	538	ATPase, Cu++ transporting, alpha polypeptide	removal of superoxide radicals	Biological process	-
RXRB	6257	retinoid X receptor, beta	RNA polymerase II distal enhancer sequence-specific DNA binding	Molecular function	-
NOC3L	64318	nucleolar complex associated 3 homolog (S. cerevisiae)	fat cell differentiation	Biological process	-
TRPC7	57113	transient receptor potential cation channel, subfamily C, member 7	cytosolic calcium ion homeostasis	Biological process	-
APOC3	345	apolipoprotein C-III	negative regulation of fatty acid biosynthetic process	Biological process	11060345
OPRK1	4986	opioid receptor, kappa 1	locomotory behavior	Biological process	-
CKAP5	9793	cytoskeleton associated protein 5	microtubule plus-end	Cellular component	21646404
PITPNM1	9600	phosphatidylinositol transfer protein, membrane-associated 1	lipid particle	Cellular component	-
SULT1E1	6783	sulfotransferase family 1E, estrogen-preferring, member 1	xenobiotic metabolic process	Biological process	-
CARD9	64170	caspase recruitment domain family, member 9	response to fungus	Biological process	-
STX1A	6804	syntaxin 1A (brain)	protein N-terminus binding	Molecular function	-
PDGFB	5155	platelet-derived growth factor beta polypeptide	protein homodimerization activity	Molecular function	2836953
PRKCD	5580	protein kinase C, delta	nucleus	Cellular component	15632189
SRPRB	58477	signal recognition particle receptor, B subunit	SRP-dependent cotranslational protein targeting to membrane	Biological process	-
LYL1	4066	lymphoblastic leukemia associated hematopoiesis regulator 1	blood vessel maturation	Biological process	20418284
LEF1	51176	lymphoid enhancer-binding factor 1	histone H4 acetylation	Biological process	20363964
FNIP1	96459	folliculin interacting protein 1	positive regulation of B cell apoptotic process	Biological process	-
DMRTC1	63947	DMRT-like family C1	sex differentiation	Biological process	-
JUNB	3726	jun B proto-oncogene	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
OR11A1	26531	olfactory receptor, family 11, subfamily A, member 1	plasma membrane	Cellular component	-
SH3GL1	6455	SH3-domain GRB2-like 1	cytoplasm	Cellular component	-
NSMCE1	197370	non-SMC element 1 homolog (S. cerevisiae)	protein sumoylation	Biological process	-
SRP14	6727	signal recognition particle 14kDa (homologous Alu RNA binding protein)	7S RNA binding	Molecular function	-
ZBTB33	10009	zinc finger and BTB domain containing 33	methyl-CpG binding	Molecular function	16354688
OR2I1P	442197	olfactory receptor, family 2, subfamily I, member 1 pseudogene	integral component of membrane	Cellular component	-
ICE2	79664	interactor of little elongation complex ELL subunit 2	snRNA transcription from RNA polymerase III promoter	Biological process	23932780
BRDT	676	bromodomain, testis-specific	lysine-acetylated histone binding	Molecular function	-
CNR2	1269	cannabinoid receptor 2 (macrophage)	response to amphetamine	Biological process	-
STAT5B	6777	signal transducer and activator of transcription 5B	positive regulation of gamma-delta T cell differentiation	Biological process	-
MLH3	27030	mutL homolog 3	male meiosis	Biological process	-
RASSF9	9182	Ras association (RalGDS/AF-6) domain family (N-terminal) member 9	endosome	Cellular component	9837933
LIN52	91750	lin-52 DREAM MuvB core complex component	nucleoplasm	Cellular component	-
ENOSF1	55556	enolase superfamily member 1	mitochondrion	Cellular component	-
FLNA	2316	filamin A, alpha	negative regulation of protein catabolic process	Biological process	18322202
ABCC13	150000	ATP-binding cassette, sub-family C (CFTR/MRP), member 13, pseudogene	integral component of membrane	Cellular component	-
DARS	1615	aspartyl-tRNA synthetase	translation	Biological process	8449960
SERTAD1	29950	SERTA domain containing 1	regulation of cyclin-dependent protein serine/threonine kinase activity	Biological process	6434876
RELA	5970	v-rel avian reticuloendotheliosis viral oncogene homolog A	transcription regulatory region DNA binding	Molecular function	17350185
UBE2I	7329	ubiquitin-conjugating enzyme E2I	regulation of receptor activity	Biological process	-
SUPT4H1	6827	suppressor of Ty 4 homolog 1 (S. cerevisiae)	zinc ion binding	Molecular function	-
TFPI2	7980	tissue factor pathway inhibitor 2	nucleus	Cellular component	-
NOD1	10392	nucleotide-binding oligomerization domain containing 1	activation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	10329646
MYH9	4627	myosin, heavy chain 9, non-muscle	establishment of meiotic spindle localization	Biological process	-
RPL28	6158	ribosomal protein L28	positive regulation of protein targeting to mitochondrion	Biological process	24912190
DIS3	22894	DIS3 exosome endoribonuclease and 3'-5' exoribonuclease	nucleolus	Cellular component	20531386
OR5A1	219982	olfactory receptor, family 5, subfamily A, member 1	olfactory receptor activity	Molecular function	-
SNRPN	6638	small nuclear ribonucleoprotein polypeptide N	catalytic step 2 spliceosome	Cellular component	-
HIST1H2BG	8339	histone cluster 1, H2bg	nucleoplasm	Cellular component	-
MDK	4192	midkine (neurite growth-promoting factor 2)	nervous system development	Biological process	9384573
GJD3	125111	gap junction protein, delta 3, 31.9kDa	connexon complex	Cellular component	12154091
PGM2	55276	phosphoglucomutase 2	extracellular exosome	Cellular component	23533145
TNFRSF11A	8792	tumor necrosis factor receptor superfamily, member 11a, NFKB activator	external side of plasma membrane	Cellular component	9367155
NFKBIA	4792	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	cytoplasmic sequestering of transcription factor	Biological process	1493333
FOXA1	3169	forkhead box A1	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
JCHAIN	3512	joining chain of multimeric IgA and IgM	adaptive immune response	Biological process	21786026
CALHM1	255022	calcium homeostasis modulator 1	ion transmembrane transport	Biological process	-
MS4A14	84689	membrane-spanning 4-domains, subfamily A, member 14	integral component of membrane	Cellular component	-
PSMD8	5714	proteasome (prosome, macropain) 26S subunit, non-ATPase, 8	positive regulation of canonical Wnt signaling pathway	Biological process	-
FBXL14	144699	F-box and leucine-rich repeat protein 14	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	19955572
TRIM11	81559	tripartite motif containing 11	positive regulation of viral entry into host cell	Biological process	18248090
RBMY1E	378950	RNA binding motif protein, Y-linked, family 1, member E	nucleus	Cellular component	-
CHCHD3	54927	coiled-coil-helix-coiled-coil-helix domain containing 3	cytoplasm	Cellular component	22567091
PRKCZ	5590	protein kinase C, zeta	protein kinase C activity	Molecular function	-
ATP5G2	517	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)	ATP hydrolysis coupled proton transport	Biological process	-
HIVEP2	3097	human immunodeficiency virus type I enhancer binding protein 2	metal ion binding	Molecular function	-
DDX58	23586	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	cytoplasmic pattern recognition receptor signaling pathway in response to virus	Biological process	21616437
SYCP2	10388	synaptonemal complex protein 2	fertilization	Biological process	-
MUC1	4582	mucin 1, cell surface associated	integral component of plasma membrane	Cellular component	1697589
ZAK	51776	sterile alpha motif and leucine zipper containing kinase AZK	cell death	Biological process	11836244
MYOD1	4654	myogenic differentiation 1	protein phosphorylation	Biological process	3175662
HSPB11	51668	heat shock protein family B (small), member 11	skeletal system development	Biological process	-
EIF2AK2	5610	eukaryotic translation initiation factor 2-alpha kinase 2	negative regulation of apoptotic process	Biological process	-
CYP4F22	126410	cytochrome P450, family 4, subfamily F, polypeptide 22	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	Molecular function	-
DOCK10	55619	dedicator of cytokinesis 10	protein binding	Molecular function	25416956
VPS41	27072	vacuolar protein sorting 41 homolog (S. cerevisiae)	protein targeting to vacuole	Biological process	-
EGFR	1956	epidermal growth factor receptor	positive regulation of synaptic transmission, glutamatergic	Biological process	-
LRP2	4036	low density lipoprotein receptor-related protein 2	apical plasma membrane	Cellular component	-
PFKFB1	5207	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	response to starvation	Biological process	-
PEX19	5824	peroxisomal biogenesis factor 19	negative regulation of lipid binding	Biological process	19715730
ANO7	50636	anoctamin 7	cytosol	Cellular component	-
FARS2	10667	phenylalanyl-tRNA synthetase 2, mitochondrial	gene expression	Biological process	-
RBMX	27316	RNA binding motif protein, X-linked	core promoter binding	Molecular function	18541147
ITPR1	3708	inositol 1,4,5-trisphosphate receptor, type 1	calcineurin complex	Cellular component	-
TRIM16	10626	tripartite motif containing 16	DNA binding	Molecular function	16636064
NLRP6	171389	NLR family, pyrin domain containing 6	regulation of autophagy	Biological process	-
PTCHD2	57540	patched domain containing 2	endoplasmic reticulum	Cellular component	19179482
DLX2	1746	distal-less homeobox 2	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment	Biological process	-
HSPB11	51668	heat shock protein family B (small), member 11	ciliary tip	Cellular component	-
DHCR24	1718	24-dehydrocholesterol reductase	protein localization	Biological process	-
HLA-F	3134	major histocompatibility complex, class I, F	membrane	Cellular component	19946888
ZNF154	7710	zinc finger protein 154	regulation of transcription, DNA-templated	Biological process	7557990
CCL15	6359	chemokine (C-C motif) ligand 15	cell-cell signaling	Biological process	9548457
BAP1	8314	BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)	positive regulation of protein targeting to mitochondrion	Biological process	24270810
GRIK1	2897	glutamate receptor, ionotropic, kainate 1	integral component of plasma membrane	Cellular component	8260617
AKR1B15	441282	aldo-keto reductase family 1, member B15	cytosol	Cellular component	-
ASAP2	8853	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	positive regulation of GTPase activity	Biological process	-
PAX2	5076	paired box 2	aging	Biological process	-
SLITRK5	26050	SLIT and NTRK-like family, member 5	dendrite morphogenesis	Biological process	-
NDUFS3	4722	NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)	respiratory electron transport chain	Biological process	-
OPRM1	4988	opioid receptor, mu 1	adenylate cyclase-activating dopamine receptor signaling pathway	Biological process	-
EPB41L5	57669	erythrocyte membrane protein band 4.1 like 5	ruffle membrane	Cellular component	-
SMARCA5	8467	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	nuclear replication fork	Cellular component	15543136
FGF10	2255	fibroblast growth factor 10	positive regulation of keratinocyte proliferation	Biological process	17449030
EIF3CL	728689	eukaryotic translation initiation factor 3, subunit C-like	eukaryotic 48S preinitiation complex	Cellular component	-
OR1F12	442179	olfactory receptor, family 1, subfamily F, member 12	integral component of membrane	Cellular component	-
THBS1	7057	thrombospondin 1	laminin binding	Molecular function	6693501
ARHGEF28	64283	Rho guanine nucleotide exchange factor (GEF) 28	intracellular signal transduction	Biological process	-
MIOX	55586	myo-inositol oxygenase	cytoplasm	Cellular component	-
ETHE1	23474	ethylmalonic encephalopathy 1	mitochondrial matrix	Cellular component	-
HNRNPM	4670	heterogeneous nuclear ribonucleoprotein M	protein domain specific binding	Molecular function	11984006
AQP9	366	aquaporin 9	immune response	Biological process	9514918
CRYAB	1410	crystallin, alpha B	unfolded protein binding	Molecular function	16303126
OR2T29	343563	olfactory receptor, family 2, subfamily T, member 29	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
IFT57	55081	intraflagellar transport 57	primary cilium	Cellular component	-
RHOB	388	ras homolog family member B	blood coagulation	Biological process	-
RRAS2	22800	related RAS viral (r-ras) oncogene homolog 2	endoplasmic reticulum	Cellular component	10777492
TBP	6908	TATA box binding protein	repressing transcription factor binding	Molecular function	18838386
POU4F2	5458	POU class 4 homeobox 2	neuron differentiation	Biological process	-
PARVA	55742	parvin, alpha	outflow tract septum morphogenesis	Biological process	-
NLK	51701	nemo-like kinase	negative regulation of Wnt signaling pathway	Biological process	-
TOP3A	7156	topoisomerase (DNA) III alpha	meiotic nuclear division	Biological process	8622991
POMT1	10585	protein-O-mannosyltransferase 1	dolichyl-phosphate-mannose-protein mannosyltransferase activity	Molecular function	-
TRAF3	7187	TNF receptor-associated factor 3	ligase activity	Molecular function	-
SGK223	157285	homolog of rat pragma of Rnd2	non-membrane spanning protein tyrosine kinase activity	Molecular function	-
CCL2	6347	chemokine (C-C motif) ligand 2	chemotaxis	Biological process	10623817
WBSCR17	64409	Williams-Beuren syndrome chromosome region 17	integral component of membrane	Cellular component	-
WDPCP	51057	WD repeat containing planar cell polarity effector	establishment of protein localization	Biological process	-
SUMO1	7341	small ubiquitin-like modifier 1	dendrite	Cellular component	-
PIP4K2C	79837	phosphatidylinositol-5-phosphate 4-kinase, type II, gamma	ATP binding	Molecular function	-
TAF1C	9013	TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa	chromatin silencing at rDNA	Biological process	-
FAS	355	Fas cell surface death receptor	renal system process	Biological process	-
RAB33A	9363	RAB33A, member RAS oncogene family	regulation of autophagosome assembly	Biological process	-
C8B	732	complement component 8, beta polypeptide	complement activation, classical pathway	Biological process	-
IYD	389434	iodotyrosine deiodinase	small molecule metabolic process	Biological process	-
SLC25A18	83733	solute carrier family 25 (glutamate carrier), member 18	integral component of membrane	Cellular component	-
P2RX4	5025	purinergic receptor P2X, ligand gated ion channel, 4	extracellular ATP-gated cation channel activity	Molecular function	10515189
MEIS2	4212	Meis homeobox 2	pancreas development	Biological process	-
MESP1	55897	mesoderm posterior basic helix-loop-helix transcription factor 1	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
GLI1	2735	GLI family zinc finger 1	transcription regulatory region DNA binding	Molecular function	17035233
PDE1A	5136	phosphodiesterase 1A, calmodulin-dependent	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity	Molecular function	8557689
MYOC	4653	myocilin, trabecular meshwork inducible glucocorticoid response	bone development	Biological process	-
PTPN11	5781	protein tyrosine phosphatase, non-receptor type 11	fibroblast growth factor receptor signaling pathway	Biological process	-
MYO5A	4644	myosin VA (heavy chain 12, myoxin)	synapse organization	Biological process	-
PPARG	5468	peroxisome proliferator-activated receptor gamma	long-chain fatty acid transport	Biological process	-
IGF2R	3482	insulin-like growth factor 2 receptor	trans-Golgi network transport vesicle	Cellular component	15078902
CRTAC1	55118	cartilage acidic protein 1	protein binding	Molecular function	25416956
SYT5	6861	synaptotagmin V	recycling endosome membrane	Cellular component	-
SHH	6469	sonic hedgehog	glycoprotein binding	Molecular function	-
BEST1	7439	bestrophin 1	chloride transmembrane transport	Biological process	-
SYTL2	54843	synaptotagmin-like 2	exocytosis	Biological process	18812475
ZNF664-FAM101A	100533183	filamin-interacting protein FAM101A	cytoskeleton	Cellular component	-
SLC1A2	6506	solute carrier family 1 (glial high affinity glutamate transporter), member 2	membrane	Cellular component	7521911
KIF3B	9371	kinesin family member 3B	anterograde axon cargo transport	Biological process	7559760
NGF	4803	nerve growth factor (beta polypeptide)	sensory perception of pain	Biological process	-
GRIK4	2900	glutamate receptor, ionotropic, kainate 4	synaptic transmission, glutamatergic	Biological process	-
CYP19A1	1588	cytochrome P450, family 19, subfamily A, polypeptide 1	sterol metabolic process	Biological process	-
APOBEC1	339	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	lipoprotein biosynthetic process	Biological process	-
FOXH1	8928	forkhead box H1	aorta morphogenesis	Biological process	-
CRYZL1	9946	crystallin, zeta (quinone reductase)-like 1	quinone metabolic process	Biological process	10191096
NFAM1	150372	NFAT activating protein with ITAM motif 1	membrane raft	Cellular component	-
EIF2AK2	5610	eukaryotic translation initiation factor 2-alpha kinase 2	eukaryotic translation initiation factor 2alpha kinase activity	Molecular function	10866685
ASH2L	9070	ash2 (absent, small, or homeotic)-like (Drosophila)	transcription regulatory region DNA binding	Molecular function	16603732
MAGED1	9500	melanoma antigen family D1	negative regulation of epithelial cell proliferation	Biological process	15930293
DENND2A	27147	DENN/MADD domain containing 2A	cytoplasm	Cellular component	-
FOXN1	8456	forkhead box N1	regulation of transcription from RNA polymerase II promoter	Biological process	10767081
WNT9A	7483	wingless-type MMTV integration site family, member 9A	negative regulation of canonical Wnt signaling pathway	Biological process	-
SLMO1	10650	slowmo homolog 1 (Drosophila)	phosphatidic acid transporter activity	Molecular function	-
KCNAB1	7881	potassium channel, voltage gated subfamily A regulatory beta subunit 1	regulation of delayed rectifier potassium channel activity	Biological process	-
CCDC88A	55704	coiled-coil domain containing 88A	membrane organization	Biological process	15882442
JDP2	122953	Jun dimerization protein 2	sequence-specific DNA binding	Molecular function	-
TMEM69	51249	transmembrane protein 69	integral component of membrane	Cellular component	-
TPK1	27010	thiamin pyrophosphokinase 1	thiamine metabolic process	Biological process	-
RGS8	85397	regulator of G-protein signaling 8	positive regulation of GTPase activity	Biological process	-
MAST2	23139	microtubule associated serine/threonine kinase 2	protein serine/threonine kinase activity	Molecular function	-
TACSTD2	4070	tumor-associated calcium signal transducer 2	receptor activity	Molecular function	7665234
MTERF1	7978	mitochondrial transcription termination factor 1	mitochondrion	Cellular component	9118945
LEP	3952	leptin	circadian rhythm	Biological process	-
HAND2	9464	heart and neural crest derivatives expressed 2	negative regulation of sequence-specific DNA binding transcription factor activity	Biological process	-
GDF5	8200	growth differentiation factor 5	cell-cell signaling	Biological process	8589725
CYBA	1535	cytochrome b-245, alpha polypeptide	secretory granule	Cellular component	12005167
ALDH9A1	223	aldehyde dehydrogenase 9 family, member A1	cellular nitrogen compound metabolic process	Biological process	-
NOTCH2	4853	notch 2	ligand-activated RNA polymerase II transcription factor binding transcription factor activity	Molecular function	9244302
USP30	84749	ubiquitin specific peptidase 30	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological process	-
VDR	7421	vitamin D (1,25- dihydroxyvitamin D3) receptor	mammary gland branching involved in pregnancy	Biological process	-
TCIRG1	10312	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3	apical plasma membrane	Cellular component	15800125
CTGF	1490	connective tissue growth factor	extracellular region	Cellular component	-
C9orf72	203228	chromosome 9 open reading frame 72	protein binding	Molecular function	24549040
CROCC	9696	ciliary rootlet coiled-coil, rootletin	protein binding	Molecular function	18086858
SCG5	6447	secretogranin V	unfolded protein binding	Molecular function	7913882
AP2A1	160	adaptor-related protein complex 2, alpha 1 subunit	intracellular protein transport	Biological process	12036598
CDYL	9425	chromodomain protein, Y-like	histone acetyltransferase activity	Molecular function	-
RAB5B	5869	RAB5B, member RAS oncogene family	metabolic process	Biological process	1541686
SOCS7	30837	suppressor of cytokine signaling 7	intracellular membrane-bounded organelle	Cellular component	-
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	ion channel binding	Molecular function	19996314
PCSK2	5126	proprotein convertase subtilisin/kexin type 2	protein binding	Molecular function	7913882
DAOA	267012	D-amino acid oxidase activator	perinuclear region of cytoplasm	Cellular component	21679769
BGLAP	632	bone gamma-carboxyglutamate (gla) protein	response to vitamin D	Biological process	17023519
WRN	7486	Werner syndrome, RecQ helicase-like	response to UV-C	Biological process	17563354
SCN4B	6330	sodium channel, voltage gated, type IV beta subunit	voltage-gated sodium channel activity	Molecular function	12930796
MCHR1	2847	melanin-concentrating hormone receptor 1	cytosol	Cellular component	10421367
PSEN1	5663	presenilin 1	cell cortex	Cellular component	-
STUB1	10273	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase	misfolded or incompletely synthesized protein catabolic process	Biological process	16831871
GATAD1	57798	GATA zinc finger domain containing 1	nucleoplasm	Cellular component	-
TG	7038	thyroglobulin	extracellular space	Cellular component	-
PEX5	5830	peroxisomal biogenesis factor 5	peroxisomal matrix	Cellular component	11336669
RAMP1	10267	receptor (G protein-coupled) activity modifying protein 1	protein transporter activity	Molecular function	10882736
PIP5K1A	8394	phosphatidylinositol-4-phosphate 5-kinase, type I, alpha	cytosol	Cellular component	-
FABP5	2171	fatty acid binding protein 5 (psoriasis-associated)	glucose metabolic process	Biological process	-
FOXR2	139628	forkhead box R2	nucleus	Cellular component	-
IL17RD	54756	interleukin 17 receptor D	interleukin-17 receptor activity	Molecular function	-
NPLOC4	55666	nuclear protein localization 4 homolog (S. cerevisiae)	Golgi organization	Biological process	11574150
SLURP1	57152	secreted LY6/PLAUR domain containing 1	neuromuscular process controlling posture	Biological process	-
MECOM	2122	MDS1 and EVI1 complex locus	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
PAK1	5058	p21 protein (Cdc42/Rac)-activated kinase 1	activation of protein kinase activity	Biological process	-
UBL5	59286	ubiquitin-like 5	protein tag	Molecular function	-
EIF4B	1975	eukaryotic translation initiation factor 4B	protein binding	Molecular function	21887822
CDKN2A	1029	cyclin-dependent kinase inhibitor 2A	ubiquitin-protein transferase inhibitor activity	Molecular function	-
LDHB	3945	lactate dehydrogenase B	cellular metabolic process	Biological process	-
UBC	7316	ubiquitin C	Fc-epsilon receptor signaling pathway	Biological process	-
STK26	51765	serine/threonine protein kinase 26	programmed cell death	Biological process	-
COMMD6	170622	COMM domain containing 6	transcription, DNA-templated	Biological process	-
AADAT	51166	aminoadipate aminotransferase	L-kynurenine metabolic process	Biological process	-
PJA1	64219	praja ring finger 1, E3 ubiquitin protein ligase	zinc ion binding	Molecular function	-
OPRD1	4985	opioid receptor, delta 1	axon terminus	Cellular component	-
PLK3	1263	polo-like kinase 3	Golgi stack	Cellular component	14980500
STAG1	10274	stromal antigen 1	protein binding	Molecular function	15855230
ANKRD26	22852	ankyrin repeat domain 26	negative regulation of fat cell differentiation	Biological process	-
NHP2L1	4809	NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)	nucleolus	Cellular component	10593953
IGBP1	3476	immunoglobulin (CD79A) binding protein 1	regulation of microtubule-based movement	Biological process	18949047
P2RX4	5025	purinergic receptor P2X, ligand gated ion channel, 4	positive regulation of prostaglandin secretion	Biological process	10899068
SLC2A6	11182	solute carrier family 2 (facilitated glucose transporter), member 6	sugar:proton symporter activity	Molecular function	-
HGF	3082	hepatocyte growth factor (hepapoietin A; scatter factor)	blood coagulation	Biological process	-
CDKN2A	1029	cyclin-dependent kinase inhibitor 2A	negative regulation of immature T cell proliferation in thymus	Biological process	-
KCNB2	9312	potassium channel, voltage gated Shab related subfamily B, member 2	synaptic transmission	Biological process	-
MSH2	4436	mutS homolog 2	DNA-dependent ATPase activity	Molecular function	-
RPS19	6223	ribosomal protein S19	gene expression	Biological process	-
UBTF	7343	upstream binding transcription factor, RNA polymerase I	protein binding	Molecular function	16777843
MRPS34	65993	mitochondrial ribosomal protein S34	mitochondrial inner membrane	Cellular component	-
JAK2	3717	Janus kinase 2	endosome lumen	Cellular component	-
DECR1	1666	2,4-dienoyl CoA reductase 1, mitochondrial	cellular lipid metabolic process	Biological process	-
IFI30	10437	interferon, gamma-inducible protein 30	lysosome	Cellular component	10639150
PTK2	5747	protein tyrosine kinase 2	protein kinase activity	Molecular function	-
NEDD9	4739	neural precursor cell expressed, developmentally down-regulated 9	focal adhesion	Cellular component	-
LPA	4018	lipoprotein, Lp(a)	lipid transport	Biological process	-
SCN3B	55800	sodium channel, voltage gated, type III beta subunit	regulation of sodium ion transmembrane transporter activity	Biological process	20042427
OR6B1	135946	olfactory receptor, family 6, subfamily B, member 1	plasma membrane	Cellular component	-
NCK1	4690	NCK adaptor protein 1	cell-cell junction	Cellular component	-
MRPL18	29074	mitochondrial ribosomal protein L18	mitochondrial translational elongation	Biological process	-
MT3	4504	metallothionein 3	negative regulation of apoptotic process	Biological process	15129022
IL31RA	133396	interleukin 31 receptor A	cytokine binding	Molecular function	11877449
FLNB	2317	filamin B, beta	cytokine-mediated signaling pathway	Biological process	-
ATP2A3	489	ATPase, Ca++ transporting, ubiquitous	calcium ion transport	Biological process	8809064
PIDD1	55367	p53-induced death domain protein 1	nucleus	Cellular component	21726810
KCNJ4	3761	potassium channel, inwardly rectifying subfamily J, member 4	synaptic transmission	Biological process	-
VAV3	10451	vav 3 guanine nucleotide exchange factor	lamellipodium assembly	Biological process	-
PDGFRA	5156	platelet-derived growth factor receptor, alpha polypeptide	positive regulation of phospholipase C activity	Biological process	1646396
HSPB1	3315	heat shock 27kDa protein 1	gene expression	Biological process	-
ELK3	2004	ELK3, ETS-domain protein (SRF accessory protein 2)	sequence-specific DNA binding transcription factor activity	Molecular function	7851904
CHRNA7	1139	cholinergic receptor, nicotinic, alpha 7 (neuronal)	cation transmembrane transport	Biological process	-
SOX9	6662	SRY (sex determining region Y)-box 9	epithelial tube branching involved in lung morphogenesis	Biological process	-
EGFR	1956	epidermal growth factor receptor	response to UV-A	Biological process	18483258
APBA1	320	amyloid beta (A4) precursor protein-binding, family A, member 1	PDZ domain binding	Molecular function	-
VAV3	10451	vav 3 guanine nucleotide exchange factor	Rac guanyl-nucleotide exchange factor activity	Molecular function	-
TNF	7124	tumor necrosis factor	response to gold nanoparticle	Biological process	-
GAS6	2621	growth arrest-specific 6	cellular protein metabolic process	Biological process	-
SLC2A3	6515	solute carrier family 2 (facilitated glucose transporter), member 3	extracellular exosome	Cellular component	20458337
BRD4	23476	bromodomain containing 4	p53 binding	Molecular function	23317504
ADCY4	196883	adenylate cyclase 4	neurotrophin TRK receptor signaling pathway	Biological process	-
HBP1	26959	HMG-box transcription factor 1	DNA binding	Molecular function	-
NR5A1	2516	nuclear receptor subfamily 5, group A, member 1	enzyme binding	Molecular function	17664281
PRKCI	5584	protein kinase C, iota	Golgi membrane	Cellular component	-
CCR6	1235	chemokine (C-C motif) receptor 6	G-protein coupled receptor signaling pathway	Biological process	-
ARL6	84100	ADP-ribosylation factor-like 6	regulation of smoothened signaling pathway	Biological process	-
KCNJ3	3760	potassium channel, inwardly rectifying subfamily J, member 3	response to electrical stimulus	Biological process	-
TNFAIP3	7128	tumor necrosis factor, alpha-induced protein 3	positive regulation of protein catabolic process	Biological process	21127049
TRADD	8717	TNFRSF1A-associated via death domain	extrinsic apoptotic signaling pathway via death domain receptors	Biological process	8612133
SH3KBP1	30011	SH3-domain kinase binding protein 1	focal adhesion	Cellular component	-
NENF	29937	neudesin neurotrophic factor	extracellular space	Cellular component	-
UGT1A4	54657	UDP glucuronosyltransferase 1 family, polypeptide A4	enzyme binding	Molecular function	20610558
DDR1	780	discoidin domain receptor tyrosine kinase 1	extracellular matrix organization	Biological process	-
ATG7	10533	autophagy related 7	membrane fusion	Biological process	10233149
PARK7	11315	parkinson protein 7	mercury ion binding	Molecular function	23792957
COL5A2	1290	collagen, type V, alpha 2	axon guidance	Biological process	-
UMPS	7372	uridine monophosphate synthetase	lactation	Biological process	-
VPS53	55275	vacuolar protein sorting 53 homolog (S. cerevisiae)	Golgi apparatus	Cellular component	15878329
HES1	3280	hes family bHLH transcription factor 1	positive regulation of tyrosine phosphorylation of Stat3 protein	Biological process	-
S1PR2	9294	sphingosine-1-phosphate receptor 2	activation of MAPK activity	Biological process	10617617
TAC4	255061	tachykinin 4 (hemokinin)	tachykinin receptor signaling pathway	Biological process	-
TRIM54	57159	tripartite motif containing 54	zinc ion binding	Molecular function	11243782
RHOA	387	ras homolog family member A	positive regulation of axonogenesis	Biological process	-
MSRA	4482	methionine sulfoxide reductase A	protein repair	Biological process	-
SGCE	8910	sarcoglycan, epsilon	dendrite	Cellular component	-
USP25	29761	ubiquitin specific peptidase 25	protein K48-linked deubiquitination	Biological process	18538659
DHX58	79132	DEXH (Asp-Glu-X-His) box polypeptide 58	innate immune response	Biological process	-
CACNG2	10369	calcium channel, voltage-dependent, gamma subunit 2	endocytic vesicle membrane	Cellular component	-
HLA-DRB4	3126	major histocompatibility complex, class II, DR beta 4	T-helper 1 type immune response	Biological process	-
CREB3L3	84699	cAMP responsive element binding protein 3-like 3	cAMP response element binding	Molecular function	-
NUP50	10762	nucleoporin 50kDa	hexose transport	Biological process	-
ADCY7	113	adenylate cyclase 7	intracellular	Cellular component	-
FRMPD2	143162	FERM and PDZ domain containing 2	cytoplasm	Cellular component	-
IGLON5	402665	IgLON family member 5	single organismal cell-cell adhesion	Biological process	-
ZIC1	7545	Zic family member 1	metal ion binding	Molecular function	-
HMGB1	3146	high mobility group box 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	19223331
TNNT3	7140	troponin T type 3 (skeletal, fast)	calcium-dependent protein binding	Molecular function	8987992
OR7D4	125958	olfactory receptor, family 7, subfamily D, member 4	G-protein coupled receptor signaling pathway	Biological process	-
OSGEPL1	64172	O-sialoglycoprotein endopeptidase-like 1	transferase activity, transferring acyl groups other than amino-acyl groups	Molecular function	-
SMAD4	4089	SMAD family member 4	transforming growth factor beta receptor signaling pathway	Biological process	-
NANOS2	339345	nanos homolog 2 (Drosophila)	nucleus	Cellular component	22899867
ERBB2	2064	erb-b2 receptor tyrosine kinase 2	signal transduction	Biological process	10572067
TTC39A	22996	tetratricopeptide repeat domain 39A	cellular_component	Cellular component	-
RNLS	55328	renalase, FAD-dependent amine oxidase	dopamine metabolic process	Biological process	-
MUC17	140453	mucin 17, cell surface associated	protein binding	Molecular function	17990980
CD86	942	CD86 molecule	positive regulation of interleukin-4 biosynthetic process	Biological process	9915850
CES3	23491	carboxylesterase 3	endoplasmic reticulum lumen	Cellular component	-
GNAT1	2779	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1	negative regulation of cyclic-nucleotide phosphodiesterase activity	Biological process	-
TRUB1	142940	TruB pseudouridine (psi) synthase family member 1	tRNA modification	Biological process	-
GMPS	8833	guanine monphosphate synthase	glutamine metabolic process	Biological process	-
MAP2K1	5604	mitogen-activated protein kinase kinase 1	regulation of early endosome to late endosome transport	Biological process	19565474
DENND5A	23258	DENN/MADD domain containing 5A	retrograde transport, endosome to Golgi	Biological process	19619496
SLC18A2	6571	solute carrier family 18 (vesicular monoamine transporter), member 2	heat shock protein binding	Molecular function	-
CT45A3	441519	cancer/testis antigen family 45, member A3	protein binding	Molecular function	21516116
MRPS22	56945	mitochondrial ribosomal protein S22	mitochondrial translational termination	Biological process	-
BCLAF1	9774	BCL2-associated transcription factor 1	regulation of DNA-templated transcription in response to stress	Biological process	17938203
SDHD	6392	succinate dehydrogenase complex, subunit D, integral membrane protein	integral component of membrane	Cellular component	-
HSPA1A	3303	heat shock 70kDa protein 1A	COP9 signalosome	Cellular component	18850735
POLR2L	5441	polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa	RNA polymerase III activity	Molecular function	-
LYST	1130	lysosomal trafficking regulator	pigmentation	Biological process	10648412
UBE2K	3093	ubiquitin-conjugating enzyme E2K	ligase activity	Molecular function	-
TULP1	7287	tubby like protein 1	retina homeostasis	Biological process	15557452
PRKAA1	5562	protein kinase, AMP-activated, alpha 1 catalytic subunit	chromatin binding	Molecular function	-
BICD2	23299	bicaudal D homolog 2 (Drosophila)	cytoplasmic vesicle	Cellular component	-
C9	735	complement component 9	blood microparticle	Cellular component	22516433
C22orf23	84645	chromosome 22 open reading frame 23	molecular_function	Molecular function	-
UHMK1	127933	U2AF homology motif (UHM) kinase 1	regulation of protein export from nucleus	Biological process	12093740
INPP5E	56623	inositol polyphosphate-5-phosphatase, 72 kDa	ruffle	Cellular component	-
APLP2	334	amyloid beta (A4) precursor-like protein 2	integral component of membrane	Cellular component	8485127
KHK	3795	ketohexokinase (fructokinase)	fructokinase activity	Molecular function	12941785
KIF13A	63971	kinesin family member 13A	trans-Golgi network membrane	Cellular component	-
NCAPD3	23310	non-SMC condensin II complex, subunit D3	mitotic cell cycle	Biological process	-
PSMD10	5716	proteasome (prosome, macropain) 26S subunit, non-ATPase, 10	protein polyubiquitination	Biological process	-
PRNP	5621	prion protein	mitochondrial outer membrane	Cellular component	21478263
ZNF606	80095	zinc finger protein 606	metal ion binding	Molecular function	-
TOMM40	10452	translocase of outer mitochondrial membrane 40 homolog (yeast)	cellular protein metabolic process	Biological process	-
GNA11	2767	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)	skeletal system development	Biological process	-
ADCY5	111	adenylate cyclase 5	activation of protein kinase A activity	Biological process	-
VCL	7414	vinculin	dystroglycan binding	Molecular function	18341635
PSMC3	5702	proteasome (prosome, macropain) 26S subunit, ATPase, 3	antigen processing and presentation of peptide antigen via MHC class I	Biological process	-
TRRAP	8295	transformation/transcription domain-associated protein	chromatin organization	Biological process	-
POLR2J3	548644	polymerase (RNA) II (DNA directed) polypeptide J3	DNA binding	Molecular function	-
RB1	5925	retinoblastoma 1	sister chromatid biorientation	Biological process	20551165
SORL1	6653	sortilin-related receptor, L(DLR class) A repeats containing	protein targeting to Golgi	Biological process	17855360
CENPB	1059	centromere protein B, 80kDa	centromeric DNA binding	Molecular function	11682612
FAM111A	63901	family with sequence similarity 111, member A	DNA replication	Biological process	24561620
TMX4	56255	thioredoxin-related transmembrane protein 4	protein disulfide isomerase activity	Molecular function	-
MRPS16	51021	mitochondrial ribosomal protein S16	mitochondrial small ribosomal subunit	Cellular component	11279123
HIST2H4A	8370	histone cluster 2, H4a	nucleus	Cellular component	14585971
CALCA	796	calcitonin-related polypeptide alpha	identical protein binding	Molecular function	23395606
TRAF2	7186	TNF receptor-associated factor 2	extrinsic apoptotic signaling pathway	Biological process	-
TLR3	7098	toll-like receptor 3	positive regulation of interleukin-12 production	Biological process	-
MAP2K1	5604	mitogen-activated protein kinase kinase 1	dendrite cytoplasm	Cellular component	-
ADIPOQ	9370	adiponectin, C1Q and collagen domain containing	adiponectin-activated signaling pathway	Biological process	-
AP2A1	160	adaptor-related protein complex 2, alpha 1 subunit	endocytic vesicle membrane	Cellular component	-
ZNF77	58492	zinc finger protein 77	biological_process	Biological process	-
FAM110B	90362	family with sequence similarity 110, member B	mitochondrion	Cellular component	-
MKKS	8195	McKusick-Kaufman syndrome	visual perception	Biological process	-
TLE4	7091	transducin-like enhancer of split 4	nucleoplasm	Cellular component	-
PPT2	9374	palmitoyl-protein thioesterase 2	palmitoyl hydrolase activity	Molecular function	10417332
NUDT7	283927	nudix (nucleoside diphosphate linked moiety X)-type motif 7	snoRNA binding	Molecular function	-
DMRTA1	63951	DMRT-like family A1	core promoter proximal region sequence-specific DNA binding	Molecular function	-
CHRNA4	1137	cholinergic receptor, nicotinic, alpha 4 (neuronal)	integral component of membrane	Cellular component	8906617
SLC22A4	6583	solute carrier family 22 (organic cation/zwitterion transporter), member 4	nucleotide binding	Molecular function	9426230
THRB	7068	thyroid hormone receptor, beta	transcription, DNA-templated	Biological process	1618799
TSPO	706	translocator protein (18kDa)	cytoplasm	Cellular component	-
MVP	9961	major vault protein	perinuclear region of cytoplasm	Cellular component	16441665
CHAC2	494143	ChaC, cation transport regulator homolog 2 (E. coli)	molecular_function	Molecular function	-
RBM4	5936	RNA binding motif protein 4	regulation of alternative mRNA splicing, via spliceosome	Biological process	12628928
LRRCC1	85444	leucine rich repeat and coiled-coil centrosomal protein 1	cytoplasm	Cellular component	-
ZMAT3	64393	zinc finger, matrin-type 3	zinc ion binding	Molecular function	-
HPS1	3257	Hermansky-Pudlak syndrome 1	integral component of plasma membrane	Cellular component	8896559
PSMB5	5693	proteasome (prosome, macropain) subunit, beta type, 5	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
PDE4A	5141	phosphodiesterase 4A, cAMP-specific	regulation of protein kinase A signaling	Biological process	-
CPEB4	80315	cytoplasmic polyadenylation element binding protein 4	nucleotide binding	Molecular function	-
NOS1	4842	nitric oxide synthase 1 (neuronal)	striated muscle contraction	Biological process	-
STAT3	6774	signal transducer and activator of transcription 3 (acute-phase response factor)	response to drug	Biological process	-
FZD4	8322	frizzled class receptor 4	clathrin-coated endocytic vesicle membrane	Cellular component	-
LOC440786	440786	uncharacterized LOC440786	extracellular exosome	Cellular component	19199708
PLXDC1	57125	plexin domain containing 1	extracellular region	Cellular component	-
ZSCAN18	65982	zinc finger and SCAN domain containing 18	nucleus	Cellular component	-
GLTP	51228	glycolipid transfer protein	glycolipid transport	Biological process	15901739
BHLHE41	79365	basic helix-loop-helix family, member e41	protein heterodimerization activity	Molecular function	-
MECP2	4204	methyl CpG binding protein 2	positive regulation of transcription, DNA-templated	Biological process	-
HTR3A	3359	5-hydroxytryptamine (serotonin) receptor 3A, ionotropic	serotonin binding	Molecular function	7565620
HTRA2	27429	HtrA serine peptidase 2	response to herbicide	Biological process	-
SDF4	51150	stromal cell derived factor 4	cytoplasm	Cellular component	17442889
SLC25A16	8034	solute carrier family 25 (mitochondrial carrier), member 16	vitamin metabolic process	Biological process	-
MOGAT2	80168	monoacylglycerol O-acyltransferase 2	diacylglycerol biosynthetic process	Biological process	-
RBM15B	29890	RNA binding motif protein 15B	nucleocytoplasmic transport	Biological process	16129689
SEC23A	10484	Sec23 homolog A (S. cerevisiae)	vesicle-mediated transport	Biological process	8898360
ARF6	382	ADP-ribosylation factor 6	myeloid cell apoptotic process	Biological process	-
SOS1	6654	son of sevenless homolog 1 (Drosophila)	small GTPase mediated signal transduction	Biological process	-
TGFB1I1	7041	transforming growth factor beta 1 induced transcript 1	I-SMAD binding	Molecular function	18762808
LCK	3932	LCK proto-oncogene, Src family tyrosine kinase	protein phosphatase binding	Molecular function	22080863
PPAP2B	8613	phosphatidic acid phosphatase type 2B	protein binding	Molecular function	20123964
TULP3	7289	tubby like protein 3	nucleolus	Cellular component	-
GATA4	2626	GATA binding protein 4	embryonic heart tube anterior/posterior pattern specification	Biological process	-
JAK3	3718	Janus kinase 3	protein phosphatase binding	Molecular function	11909529
NCOR2	9612	nuclear receptor corepressor 2	Notch binding	Molecular function	10713164
FGD6	55785	FYVE, RhoGEF and PH domain containing 6	Rho guanyl-nucleotide exchange factor activity	Molecular function	-
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
DNMT3A	1788	DNA (cytosine-5-)-methyltransferase 3 alpha	regulation of gene expression, epigenetic	Biological process	-
AHI1	54806	Abelson helper integration site 1	hindbrain development	Biological process	-
UBE2J1	51465	ubiquitin-conjugating enzyme E2, J1	ER-associated ubiquitin-dependent protein catabolic process	Biological process	21245296
ANAPC5	51433	anaphase promoting complex subunit 5	protein K11-linked ubiquitination	Biological process	18485873
LSM6	11157	LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)	small nuclear ribonucleoprotein complex	Cellular component	10523320
GORASP1	64689	golgi reassembly stacking protein 1, 65kDa	protein transport	Biological process	-
VEGFB	7423	vascular endothelial growth factor B	protein O-linked glycosylation	Biological process	-
SUPT6H	6830	suppressor of Ty 6 homolog (S. cerevisiae)	transcription, DNA-templated	Biological process	-
PRKX	5613	protein kinase, X-linked	cAMP-dependent protein kinase activity	Molecular function	10026146
EXOC8	149371	exocyst complex component 8	cellular protein metabolic process	Biological process	-
GCSH	2653	glycine cleavage system protein H (aminomethyl carrier)	methylation	Biological process	-
CTLA4	1493	cytotoxic T-lymphocyte-associated protein 4	B cell receptor signaling pathway	Biological process	17875758
DRD1	1812	dopamine receptor D1	long term synaptic depression	Biological process	-
PLK1	5347	polo-like kinase 1	centrosome	Cellular component	-
HEY1	23462	hes-related family bHLH transcription factor with YRPW motif 1	transcription from RNA polymerase II promoter	Biological process	-
SRRM4	84530	serine/arginine repetitive matrix 4	regulation of alternative mRNA splicing, via spliceosome	Biological process	-
RAP2B	5912	RAP2B, member of RAS oncogene family	regulation of protein tyrosine kinase activity	Biological process	-
RASGRP2	10235	RAS guanyl releasing protein 2 (calcium and DAG-regulated)	positive regulation of GTPase activity	Biological process	24958846
MPG	4350	N-methylpurine-DNA glycosylase	depurination	Biological process	-
DHX35	60625	DEAH (Asp-Glu-Ala-His) box polypeptide 35	poly(A) RNA binding	Molecular function	-
PLXND1	23129	plexin D1	regulation of angiogenesis	Biological process	-
BCL2L1	598	BCL2-like 1	innate immune response	Biological process	-
OTOF	9381	otoferlin	AP-2 adaptor complex binding	Molecular function	-
BUB1	699	BUB1 mitotic checkpoint serine/threonine kinase	cell proliferation	Biological process	-
SNF8	11267	SNF8, ESCRT-II complex subunit	regulation of protein catabolic process	Biological process	17714434
UGT1A5	54579	UDP glucuronosyltransferase 1 family, polypeptide A5	xenobiotic glucuronidation	Biological process	-
ZBTB17	7709	zinc finger and BTB domain containing 17	negative regulation of cell cycle	Biological process	12244100
WDR83	84292	WD repeat domain 83	cytoplasm	Cellular component	-
RNASE12	493901	ribonuclease, RNase A family, 12 (non-active)	extracellular region	Cellular component	-
PHPT1	29085	phosphohistidine phosphatase 1	negative regulation of T cell receptor signaling pathway	Biological process	18796614
RHOT2	89941	ras homolog family member T2	integral component of mitochondrial outer membrane	Cellular component	12482879
MCMBP	79892	minichromosome maintenance complex binding protein	cytoplasm	Cellular component	-
PPP3CB	5532	protein phosphatase 3, catalytic subunit, beta isozyme	calcium ion-dependent exocytosis	Biological process	-
RNASEH1	246243	ribonuclease H1	RNA binding	Molecular function	9799596
LCE3C	353144	late cornified envelope 3C	protein binding	Molecular function	25416956
EFNA4	1945	ephrin-A4	anchored component of membrane	Cellular component	-
RANBP2	5903	RAN binding protein 2	small GTPase mediated signal transduction	Biological process	-
FZD4	8322	frizzled class receptor 4	cellular response to retinoic acid	Biological process	-
PAK2	5062	p21 protein (Cdc42/Rac)-activated kinase 2	positive regulation of peptidyl-tyrosine phosphorylation	Biological process	11121037
TF	7018	transferrin	blood coagulation	Biological process	-
ASXL3	80816	additional sex combs like transcriptional regulator 3	metal ion binding	Molecular function	-
LIMD2	80774	LIM domain containing 2	zinc ion binding	Molecular function	-
SLC22A9	114571	solute carrier family 22 (organic anion transporter), member 9	anion transmembrane transport	Biological process	17393504
SLX4	84464	SLX4 structure-specific endonuclease subunit	Holliday junction resolvase complex	Cellular component	19595721
H3F3B	3021	H3 histone, family 3B (H3.3B)	regulation of gene expression, epigenetic	Biological process	-
PYGO2	90780	pygopus family PHD finger 2	post-embryonic development	Biological process	-
MCM3AP	8888	minichromosome maintenance complex component 3 associated protein	cytosol	Cellular component	16780588
PROX1	5629	prospero homeobox 1	positive regulation of cell cycle	Biological process	-
ASPHD2	57168	aspartate beta-hydroxylase domain containing 2	metal ion binding	Molecular function	-
TBX1	6899	T-box 1	retinoic acid receptor signaling pathway	Biological process	-
TRIM62	55223	tripartite motif containing 62	zinc ion binding	Molecular function	-
SPTBN4	57731	spectrin, beta, non-erythrocytic 4	central nervous system projection neuron axonogenesis	Biological process	-
SLC1A3	6507	solute carrier family 1 (glial high affinity glutamate transporter), member 3	sodium:dicarboxylate symporter activity	Molecular function	-
ATP6V1C2	245973	ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2	phagosome maturation	Biological process	-
SCD	6319	stearoyl-CoA desaturase (delta-9-desaturase)	stearoyl-CoA 9-desaturase activity	Molecular function	-
SLC6A4	6532	solute carrier family 6 (neurotransmitter transporter), member 4	negative regulation of neuron differentiation	Biological process	-
HLA-DRB1	3123	major histocompatibility complex, class II, DR beta 1	T cell receptor signaling pathway	Biological process	-
GAMT	2593	guanidinoacetate N-methyltransferase	regulation of multicellular organism growth	Biological process	-
TMEM173	340061	transmembrane protein 173	cyclic-GMP-AMP binding	Molecular function	-
EME1	146956	essential meiotic structure-specific endonuclease 1	endonuclease activity	Molecular function	-
ARNT2	9915	aryl-hydrocarbon receptor nuclear translocator 2	DNA binding	Molecular function	-
RILP	83547	Rab interacting lysosomal protein	Rab GTPase binding	Molecular function	11179213
DAPK3	1613	death-associated protein kinase 3	identical protein binding	Molecular function	18239682
APOD	347	apolipoprotein D	negative regulation of platelet-derived growth factor receptor signaling pathway	Biological process	14551159
DCHS1	8642	dachsous cadherin-related 1	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	Biological process	9199196
HRSP12	10247	heat-responsive protein 12	nucleus	Cellular component	-
WNT9B	7484	wingless-type MMTV integration site family, member 9B	response to retinoic acid	Biological process	11604992
HSPA5	3309	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	ubiquitin protein ligase binding	Molecular function	8666824
LRP4	4038	low density lipoprotein receptor-related protein 4	regulation of protein phosphorylation	Biological process	-
OR11L1	391189	olfactory receptor, family 11, subfamily L, member 1	olfactory receptor activity	Molecular function	-
TACR3	6870	tachykinin receptor 3	hyperosmotic salinity response	Biological process	-
ZFPL1	7542	zinc finger protein-like 1	vesicle-mediated transport	Biological process	-
CYP4B1	1580	cytochrome P450, family 4, subfamily B, polypeptide 1	oxygen binding	Molecular function	2574990
PHB	5245	prohibitin	early endosome	Cellular component	24732013
ADRBK1	156	adrenergic, beta, receptor kinase 1	negative regulation of striated muscle contraction	Biological process	15051637
RAB5A	5868	RAB5A, member RAS oncogene family	terminal bouton	Cellular component	16141272
RPA1	6117	replication protein A1, 70kDa	DNA damage response, detection of DNA damage	Biological process	-
MYO7A	4647	myosin VIIA	metabolic process	Biological process	-
SLK	9748	STE20-like kinase	regulation of apoptotic process	Biological process	-
CANX	821	calnexin	protein secretion	Biological process	8055875
IFNAR2	3455	interferon (alpha, beta and omega) receptor 2	type I interferon signaling pathway	Biological process	-
SIPA1L1	26037	signal-induced proliferation-associated 1 like 1	molecular_function	Molecular function	-
TRPV1	7442	transient receptor potential cation channel, subfamily V, member 1	ATP binding	Molecular function	-
TP63	8626	tumor protein p63	sympathetic nervous system development	Biological process	-
KCNA2	3737	potassium channel, voltage gated shaker related subfamily A, member 2	axon	Cellular component	-
PITX2	5308	paired-like homeodomain 2	endodermal digestive tract morphogenesis	Biological process	-
ORC5	5001	origin recognition complex, subunit 5	protein binding	Molecular function	15232106
CASP4	837	caspase 4, apoptosis-related cysteine peptidase	proteolysis	Biological process	-
GPS2	2874	G protein pathway suppressor 2	protein binding	Molecular function	11931768
UCHL5	51377	ubiquitin carboxyl-terminal hydrolase L5	omega peptidase activity	Molecular function	-
NPBWR1	2831	neuropeptides B/W receptor 1	neuropeptide signaling pathway	Biological process	-
CDO1	1036	cysteine dioxygenase type 1	response to ethanol	Biological process	-
ING4	51147	inhibitor of growth family, member 4	histone H3 acetylation	Biological process	16387653
EDA	1896	ectodysplasin A	receptor binding	Molecular function	11039935
PPP2R3A	5523	protein phosphatase 2, regulatory subunit B'', alpha	eye photoreceptor cell differentiation	Biological process	15687260
C14orf166	51637	chromosome 14 open reading frame 166	microtubule organizing center	Cellular component	-
MAST4	375449	microtubule associated serine/threonine kinase family member 4	protein phosphorylation	Biological process	-
THAP1	55145	THAP domain containing, apoptosis associated protein 1	zinc ion binding	Molecular function	15863623
HLA-DRB5	3127	major histocompatibility complex, class II, DR beta 5	negative regulation of T cell proliferation	Biological process	-
SLC30A1	7779	solute carrier family 30 (zinc transporter), member 1	detoxification of cadmium ion	Biological process	-
MRPL11	65003	mitochondrial ribosomal protein L11	mitochondrial translation	Biological process	-
FANCM	57697	Fanconi anemia, complementation group M	FANCM-MHF complex	Cellular component	20347428
TXK	7294	TXK tyrosine kinase	nucleus	Cellular component	10523612
MAMLD1	10046	mastermind-like domain containing 1	nucleus	Cellular component	-
ETV4	2118	ets variant 4	regulation of branching involved in mammary gland duct morphogenesis	Biological process	-
PEX6	5190	peroxisomal biogenesis factor 6	protein import into peroxisome matrix, translocation	Biological process	8670792
WNT5A	7474	wingless-type MMTV integration site family, member 5A	epithelial cell proliferation involved in mammary gland duct elongation	Biological process	-
RPS9	6203	ribosomal protein S9	membrane	Cellular component	19946888
ATP11A	23250	ATPase, class VI, type 11A	plasma membrane	Cellular component	-
CRYM	1428	crystallin, mu	protein homodimerization activity	Molecular function	12590647
PCDHAC1	56135	protocadherin alpha subfamily C, 1	calcium ion binding	Molecular function	-
TTLL8	164714	tubulin tyrosine ligase-like family member 8	protein polyglycylation	Biological process	-
PTPN11	5781	protein tyrosine phosphatase, non-receptor type 11	protein complex	Cellular component	-
PPARGC1A	10891	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	androgen receptor signaling pathway	Biological process	15572661
SHANK3	85358	SH3 and multiple ankyrin repeat domains 3	zinc ion binding	Molecular function	-
GLUL	2752	glutamate-ammonia ligase	cytosol	Cellular component	-
BCL10	8915	B-cell CLL/lymphoma 10	positive regulation of phosphorylation	Biological process	15125833
PFDN5	5204	prefoldin subunit 5	protein folding	Biological process	-
BBS7	55212	Bardet-Biedl syndrome 7	smoothened signaling pathway	Biological process	-
GNA13	10672	guanine nucleotide binding protein (G protein), alpha 13	membrane	Cellular component	19946888
CDIP1	29965	cell death-inducing p53 target 1	molecular_function	Molecular function	-
CYLC2	1539	cylicin, basic protein of sperm head cytoskeleton 2	spermatogenesis	Biological process	-
FOXE3	2301	forkhead box E3	iris morphogenesis	Biological process	17064680
ZFHX3	463	zinc finger homeobox 3	transcription regulatory region DNA binding	Molecular function	11312261
IL3	3562	interleukin 3	cytokine-mediated signaling pathway	Biological process	-
LDHA	3939	lactate dehydrogenase A	pyruvate metabolic process	Biological process	-
SYTL2	54843	synaptotagmin-like 2	calcium-dependent phospholipid binding	Molecular function	-
SUV39H1	6839	suppressor of variegation 3-9 homolog 1 (Drosophila)	chromatin binding	Molecular function	10202156
BRMS1	25855	breast cancer metastasis suppressor 1	positive regulation of protein deacetylation	Biological process	17000776
MAB21L1	4081	mab-21-like 1 (C. elegans)	anatomical structure morphogenesis	Biological process	8733127
PHF8	23133	PHD finger protein 8	negative regulation of chromatin silencing at rDNA	Biological process	20208542
S100A3	6274	S100 calcium binding protein A3	cytoplasm	Cellular component	-
EEF1A1	1915	eukaryotic translation elongation factor 1 alpha 1	translation elongation factor activity	Molecular function	17595531
PSMF1	9491	proteasome (prosome, macropain) inhibitor subunit 1 (PI31)	antigen processing and presentation of peptide antigen via MHC class I	Biological process	-
PPP2R4	5524	protein phosphatase 2A activator, regulatory subunit 4	metabolic process	Biological process	16916641
CCDC67	159989	coiled-coil domain containing 67	deuterosome	Cellular component	-
TCEB1	6921	transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)	transcription from RNA polymerase II promoter	Biological process	-
HDHD2	84064	haloacid dehalogenase-like hydrolase domain containing 2	metal ion binding	Molecular function	-
IGSF23	147710	immunoglobulin superfamily, member 23	integral component of membrane	Cellular component	-
MAP2K6	5608	mitogen-activated protein kinase kinase 6	transcription, DNA-templated	Biological process	-
RSPH4A	345895	radial spoke head 4 homolog A (Chlamydomonas)	molecular_function	Molecular function	-
SMEK2	57223	SMEK homolog 2, suppressor of mek1 (Dictyostelium)	protein dephosphorylation	Biological process	-
PAX3	5077	paired box 3	cell proliferation	Biological process	-
CYBB	1536	cytochrome b-245, beta polypeptide	response to nutrient	Biological process	-
F12	2161	coagulation factor XII (Hageman factor)	extracellular exosome	Cellular component	23376485
ZBTB14	7541	zinc finger and BTB domain containing 14	RNA polymerase II regulatory region sequence-specific DNA binding	Molecular function	-
LCN1	3933	lipocalin 1	negative regulation of endopeptidase activity	Biological process	8999869
RIPK3	11035	receptor-interacting serine-threonine kinase 3	NIK/NF-kappaB signaling	Biological process	-
SNX18	112574	sorting nexin 18	growth cone	Cellular component	-
SERPINE1	5054	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	transcription initiation from RNA polymerase II promoter	Biological process	-
OR10AC1	392133	olfactory receptor, family 10, subfamily AC, member 1 (gene/pseudogene)	integral component of membrane	Cellular component	-
MAP2K1	5604	mitogen-activated protein kinase kinase 1	axon guidance	Biological process	-
ITGB3	3690	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	fibronectin binding	Molecular function	24658351
ADNP	23394	activity-dependent neuroprotector homeobox	regulation of transcription, DNA-templated	Biological process	-
PROM2	150696	prominin 2	microvillus	Cellular component	12514187
FEZF1	389549	FEZ family zinc finger 1	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	-
ATP5I	521	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E	mitochondrial proton-transporting ATP synthase complex	Cellular component	12110673
NODAL	4838	nodal growth differentiation factor	vasculature development	Biological process	-
TIA1	7072	TIA1 cytotoxic granule-associated RNA binding protein	protein binding	Molecular function	12486009
HADHA	3030	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit	3-hydroxyacyl-CoA dehydrogenase activity	Molecular function	8135828
ITGB3BP	23421	integrin beta 3 binding protein (beta3-endonexin)	small GTPase mediated signal transduction	Biological process	-
GTPBP4	23560	GTP binding protein 4	GTPase activity	Molecular function	17210637
WRAP53	55135	WD repeat containing, antisense to TP53	positive regulation of telomerase activity	Biological process	19179534
OPRL1	4987	opiate receptor-like 1	neuropeptide binding	Molecular function	-
WASH3P	374666	WAS protein family homolog 3 pseudogene	recycling endosome membrane	Cellular component	-
DLL1	28514	delta-like 1 (Drosophila)	heart looping	Biological process	-
WNT1	7471	wingless-type MMTV integration site family, member 1	signal transduction in response to DNA damage	Biological process	16501043
PDGFRB	5159	platelet-derived growth factor receptor, beta polypeptide	in utero embryonic development	Biological process	-
ZNF207	7756	zinc finger protein 207	mitotic spindle assembly checkpoint	Biological process	24462186
NIPSNAP1	8508	nipsnap homolog 1 (C. elegans)	neurotransmitter binding	Molecular function	-
PELI2	57161	pellino E3 ubiquitin protein ligase family member 2	cytosol	Cellular component	-
POU4F2	5458	POU class 4 homeobox 2	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	17637757
PSMD4	5710	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	nucleoplasm	Cellular component	-
IRF7	3665	interferon regulatory factor 7	establishment of viral latency	Biological process	21490621
ADRB2	154	adrenoceptor beta 2, surface	plasma membrane	Cellular component	-
CLEC4M	10332	C-type lectin domain family 4, member M	ICAM-3 receptor activity	Molecular function	11257134
SLC24A5	283652	solute carrier family 24 (sodium/potassium/calcium exchanger), member 5	trans-Golgi network membrane	Cellular component	-
SH3GL1	6455	SH3-domain GRB2-like 1	GTPase binding	Molecular function	-
TMPRSS4	56649	transmembrane protease, serine 4	receptor-mediated endocytosis	Biological process	-
RAD51	5888	RAD51 recombinase	nucleus	Cellular component	-
DNASE1L2	1775	deoxyribonuclease I-like 2	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	Molecular function	-
MCFD2	90411	multiple coagulation factor deficiency 2	post-translational protein modification	Biological process	-
CCR2	729230	chemokine (C-C motif) receptor 2	positive regulation of hematopoietic stem cell migration	Biological process	-
PPP3R1	5534	protein phosphatase 3, regulatory subunit B, alpha	stimulatory C-type lectin receptor signaling pathway	Biological process	-
HIST1H2BB	3018	histone cluster 1, H2bb	protein heterodimerization activity	Molecular function	-
CYP2C19	1557	cytochrome P450, family 2, subfamily C, polypeptide 19	heterocycle metabolic process	Biological process	19651758
BUB3	9184	BUB3 mitotic checkpoint protein	meiotic cell cycle	Biological process	-
RPL31	6160	ribosomal protein L31	viral life cycle	Biological process	-
PSMD4	5710	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	apoptotic process	Biological process	-
ANGPT1	284	angiopoietin 1	positive regulation of ERK1 and ERK2 cascade	Biological process	18425120
PDGFRA	5156	platelet-derived growth factor receptor, alpha polypeptide	positive regulation of cell proliferation	Biological process	2554309
OR3A3	8392	olfactory receptor, family 3, subfamily A, member 3	signal transduction	Biological process	8004088
ATRAID	51374	all-trans retinoic acid-induced differentiation factor	negative regulation of osteoblast proliferation	Biological process	21723284
PALM	5064	paralemmin	filopodium membrane	Cellular component	14978216
PRM1	5619	protamine 1	nucleosome	Cellular component	-
UPF3A	65110	UPF3 regulator of nonsense transcripts homolog A (yeast)	protein binding	Molecular function	11163187
C3AR1	719	complement component 3a receptor 1	positive regulation of macrophage chemotaxis	Biological process	-
PDE1B	5153	phosphodiesterase 1B, calmodulin-dependent	apoptotic process	Biological process	8855339
CAMSAP1	157922	calmodulin regulated spectrin-associated protein 1	microtubule	Cellular component	19508979
TLN1	7094	talin 1	platelet aggregation	Biological process	23382103
LEF1	51176	lymphoid enhancer-binding factor 1	epithelial to mesenchymal transition	Biological process	-
ASH1L	55870	ash1 (absent, small, or homeotic)-like (Drosophila)	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
RUVBL2	10856	RuvB-like AAA ATPase 2	histone H2A acetylation	Biological process	14966270
SMARCA5	8467	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	helicase activity	Molecular function	-
GPR143	4935	G protein-coupled receptor 143	calcium-mediated signaling using intracellular calcium source	Biological process	18828673
APP	351	amyloid beta (A4) precursor protein	forebrain development	Biological process	-
POLD1	5424	polymerase (DNA directed), delta 1, catalytic subunit	response to UV	Biological process	3146346
VPS37B	79720	vacuolar protein sorting 37 homolog B (S. cerevisiae)	late endosome membrane	Cellular component	-
PPT1	5538	palmitoyl-protein thioesterase 1	response to stimulus	Biological process	-
LYN	4067	LYN proto-oncogene, Src family tyrosine kinase	glycosphingolipid binding	Molecular function	-
CASP8	841	caspase 8, apoptosis-related cysteine peptidase	scaffold protein binding	Molecular function	21785459
ADGRG2	10149	adhesion G protein-coupled receptor G2	cell surface	Cellular component	19581412
PCSK9	255738	proprotein convertase subtilisin/kexin type 9	Golgi apparatus	Cellular component	17461796
PLCG2	5336	phospholipase C, gamma 2 (phosphatidylinositol-specific)	phosphatidylinositol phospholipase C activity	Molecular function	-
MICB	4277	MHC class I polypeptide-related sequence B	antigen processing and presentation	Biological process	-
SQRDL	58472	sulfide quinone reductase-like (yeast)	small molecule metabolic process	Biological process	-
ENOX2	10495	ecto-NOX disulfide-thiol exchanger 2	protein binding	Molecular function	25416956
KCNJ6	3763	potassium channel, inwardly rectifying subfamily J, member 6	regulation of ion transmembrane transport	Biological process	-
TGFBR1	7046	transforming growth factor, beta receptor 1	negative regulation of transforming growth factor beta receptor signaling pathway	Biological process	-
PFN1	5216	profilin 1	phosphatidylinositol-4,5-bisphosphate binding	Molecular function	7758455
BRD9	65980	bromodomain containing 9	chromatin modification	Biological process	-
SPC24	147841	SPC24, NDC80 kinetochore complex component	nucleolus	Cellular component	-
USP22	23326	ubiquitin specific peptidase 22	cysteine-type endopeptidase activity	Molecular function	-
CDK8	1024	cyclin-dependent kinase 8	gene expression	Biological process	-
STAT3	6774	signal transducer and activator of transcription 3 (acute-phase response factor)	positive regulation of transcription, DNA-templated	Biological process	-
SPEF1	25876	sperm flagellar 1	cytoskeleton	Cellular component	-
LYVE1	10894	lymphatic vessel endothelial hyaluronan receptor 1	cell-matrix adhesion	Biological process	10037799
PAX6	5080	paired box 6	salivary gland morphogenesis	Biological process	-
LYL1	4066	lymphoblastic leukemia associated hematopoiesis regulator 1	protein binding	Molecular function	10023675
TF	7018	transferrin	basal plasma membrane	Cellular component	15880641
MAP3K14	9020	mitogen-activated protein kinase kinase kinase 14	cytosol	Cellular component	-
ZC3H8	84524	zinc finger CCCH-type containing 8	histone locus body	Cellular component	23932780
NKX2-5	1482	NK2 homeobox 5	septum secundum development	Biological process	10587520
ATP6V1C2	245973	ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2	cytosol	Cellular component	-
FDPS	2224	farnesyl diphosphate synthase	small molecule metabolic process	Biological process	-
ABCA13	154664	ATP-binding cassette, sub-family A (ABC1), member 13	cholesterol efflux	Biological process	-
EIF4H	7458	eukaryotic translation initiation factor 4H	regulation of translational initiation	Biological process	9516461
MTA3	57504	metastasis associated 1 family, member 3	nucleoplasm	Cellular component	-
PDZK1	5174	PDZ domain containing 1	PDZ domain binding	Molecular function	16236806
RAB10	10890	RAB10, member RAS oncogene family	plasma membrane	Cellular component	22908308
RNF103	7844	ring finger protein 103	endoplasmic reticulum membrane	Cellular component	-
IGHG3	3502	immunoglobulin heavy constant gamma 3 (G3m marker)	retina homeostasis	Biological process	23580065
CRK	1398	v-crk avian sarcoma virus CT10 oncogene homolog	plasma membrane	Cellular component	-
CBX8	57332	chromobox homolog 8	PcG protein complex	Cellular component	21282530
PAM16	51025	presequence translocase-associated motor 16 homolog (S. cerevisiae)	negative regulation of ATPase activity	Biological process	19564938
ZNF442	79973	zinc finger protein 442	DNA binding	Molecular function	-
LYN	4067	LYN proto-oncogene, Src family tyrosine kinase	regulation of B cell apoptotic process	Biological process	-
ZEB1	6935	zinc finger E-box binding homeobox 1	transcription coactivator activity	Molecular function	8138542
STX4	6810	syntaxin 4	endosome	Cellular component	20956541
CALM3	808	calmodulin 3 (phosphorylase kinase, delta)	ion channel binding	Molecular function	21167176
AURKAIP1	54998	aurora kinase A interacting protein 1	negative regulation of mitotic nuclear division	Biological process	12244051
RBM22	55696	RNA binding motif protein 22	nucleoplasm	Cellular component	-
ADAMTS4	9507	ADAM metallopeptidase with thrombospondin type 1 motif, 4	zinc ion binding	Molecular function	-
ATXN2	6311	ataxin 2	cytoplasmic mRNA processing body assembly	Biological process	17392519
EPOR	2057	erythropoietin receptor	decidualization	Biological process	-
SIGIRR	59307	single immunoglobulin and toll-interleukin 1 receptor (TIR) domain	membrane	Cellular component	10346978
PLOD2	5352	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2	oxidation-reduction process	Biological process	-
WISP3	8838	WNT1 inducible signaling pathway protein 3	regulation of cell growth	Biological process	-
B3GNT2	10678	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	integral component of membrane	Cellular component	-
SCAF11	9169	SR-related CTD-associated factor 11	nucleoplasm	Cellular component	-
C2CD4C	126567	C2 calcium-dependent domain containing 4C	syntaxin binding	Molecular function	-
NETO1	81832	neuropilin (NRP) and tolloid (TLL)-like 1	ionotropic glutamate receptor binding	Molecular function	-
FER	2241	fer (fps/fes related) tyrosine kinase	cell adhesion	Biological process	-
CAMK2G	818	calcium/calmodulin-dependent protein kinase II gamma	ATP binding	Molecular function	-
GAP43	2596	growth associated protein 43	protein binding	Molecular function	9139733
LTA	4049	lymphotoxin alpha	response to hypoxia	Biological process	-
ZNF385A	25946	zinc finger protein 385A	p53 binding	Molecular function	17719541
TMED10	10972	transmembrane emp24-like trafficking protein 10 (yeast)	retrograde vesicle-mediated transport, Golgi to ER	Biological process	-
MCM3	4172	minichromosome maintenance complex component 3	intracellular membrane-bounded organelle	Cellular component	-
ATP6V1A	523	ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A	lysosomal membrane	Cellular component	17897319
CALM2	805	calmodulin 2 (phosphorylase kinase, delta)	signal transduction	Biological process	-
ZNF358	140467	zinc finger protein 358	transcription, DNA-templated	Biological process	-
EPHB3	2049	EPH receptor B3	regulation of axonogenesis	Biological process	-
HSFX2	100130086	heat shock transcription factor family, X linked 2	protein binding	Molecular function	16713569
CD82	3732	CD82 molecule	protein binding	Molecular function	15205336
EXOC6	54536	exocyst complex component 6	exocyst	Cellular component	-
F8	2157	coagulation factor VIII, procoagulant component	blood coagulation	Biological process	-
PINX1	54984	PIN2/TERF1 interacting, telomerase inhibitor 1	nuclear chromosome	Cellular component	19393617
OPTC	26254	opticin	negative regulation of angiogenesis	Biological process	-
C10orf90	118611	chromosome 10 open reading frame 90	cytoplasm	Cellular component	20844083
MON2	23041	MON2 homolog (S. cerevisiae)	protein binding	Molecular function	18418388
HOXA5	3202	homeobox A5	positive regulation of apoptotic process	Biological process	10879542
FGF9	2254	fibroblast growth factor 9	male sex determination	Biological process	-
LY6G5B	58496	lymphocyte antigen 6 complex, locus G5B	biological_process	Biological process	-
CNOT4	4850	CCR4-NOT transcription complex, subunit 4	nucleotide binding	Molecular function	-
TBX20	57057	T-box 20	sequence-specific DNA binding transcription factor activity	Molecular function	-
EPPIN	57119	epididymal peptidase inhibitor	cell surface	Cellular component	-
ZP3	7784	zona pellucida glycoprotein 3 (sperm receptor)	positive regulation of phosphatidylinositol biosynthetic process	Biological process	-
ABL2	27	ABL proto-oncogene 2, non-receptor tyrosine kinase	extrinsic component of cytoplasmic side of plasma membrane	Cellular component	-
TNF	7124	tumor necrosis factor	external side of plasma membrane	Cellular component	-
CYP2A7	1549	cytochrome P450, family 2, subfamily A, polypeptide 7	coumarin metabolic process	Biological process	-
ITSN1	6453	intersectin 1 (SH3 domain protein)	guanyl-nucleotide exchange factor activity	Molecular function	9799604
SCYL1	57410	SCY1-like 1 (S. cerevisiae)	cytoplasm	Cellular component	12783284
NT5DC3	51559	5'-nucleotidase domain containing 3	metal ion binding	Molecular function	-
SPRED1	161742	sprouty-related, EVH1 domain containing 1	cytoplasm	Cellular component	-
SLC16A13	201232	solute carrier family 16, member 13	Golgi apparatus	Cellular component	24390345
NODAL	4838	nodal growth differentiation factor	endodermal cell differentiation	Biological process	21741376
TFR2	7036	transferrin receptor 2	integral component of plasma membrane	Cellular component	10409623
LUM	4060	lumican	response to growth factor	Biological process	-
MDM2	4193	MDM2 proto-oncogene, E3 ubiquitin protein ligase	regulation of protein catabolic process	Biological process	9153395
FUT9	10690	fucosyltransferase 9 (alpha (1,3) fucosyltransferase)	fucosylation	Biological process	10386598
B3GNT3	10331	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3	post-translational protein modification	Biological process	-
ICAM4	3386	intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)	protein binding	Molecular function	25416956
RALGPS1	9649	Ral GEF with PH domain and SH3 binding motif 1	guanyl-nucleotide exchange factor activity	Molecular function	10747847
ZNF366	167465	zinc finger protein 366	protein binding	Molecular function	17085477
BCL2L1	598	BCL2-like 1	suppression by virus of host apoptotic process	Biological process	15231831
TCF19	6941	transcription factor 19	regulation of transcription from RNA polymerase II promoter	Biological process	1868030
WNT5A	7474	wingless-type MMTV integration site family, member 5A	regulation of branching involved in mammary gland duct morphogenesis	Biological process	-
SLC6A12	6539	solute carrier family 6 (neurotransmitter transporter), member 12	response to organic substance	Biological process	-
AKTIP	64400	AKT interacting protein	apoptotic process	Biological process	-
NTRK1	4914	neurotrophic tyrosine kinase, receptor, type 1	sympathetic nervous system development	Biological process	-
DUSP19	142679	dual specificity phosphatase 19	JNK cascade	Biological process	-
YBEY	54059	ybeY metallopeptidase (putative)	nucleus	Cellular component	22042635
DUOXA2	405753	dual oxidase maturation factor 2	hydrogen peroxide metabolic process	Biological process	-
DUSP7	1849	dual specificity phosphatase 7	toll-like receptor 3 signaling pathway	Biological process	-
PLA2G4D	283748	phospholipase A2, group IVD (cytosolic)	phosphatidylglycerol acyl-chain remodeling	Biological process	-
PYCARD	29108	PYD and CARD domain containing	positive regulation of release of cytochrome c from mitochondria	Biological process	14730312
DDR1	780	discoidin domain receptor tyrosine kinase 1	ear development	Biological process	-
TG	7038	thyroglobulin	thyroid gland development	Biological process	15494458
U2AF1L4	199746	U2 small nuclear RNA auxiliary factor 1-like 4	spliceosomal complex	Cellular component	-
IL10	3586	interleukin 10	negative regulation of cytokine secretion involved in immune response	Biological process	10443688
VARS	7407	valyl-tRNA synthetase	aminoacyl-tRNA editing activity	Molecular function	-
MEF2C	4208	myocyte enhancer factor 2C	nucleus	Cellular component	11744164
ANAPC10	10393	anaphase promoting complex subunit 10	protein K11-linked ubiquitination	Biological process	18485873
GDE1	51573	glycerophosphodiester phosphodiesterase 1	metal ion binding	Molecular function	-
KAT2A	2648	K(lysine) acetyltransferase 2A	histone H4-K12 acetylation	Biological process	-
PAX6	5080	paired box 6	cerebellum development	Biological process	-
PARP16	54956	poly (ADP-ribose) polymerase family, member 16	integral component of membrane	Cellular component	-
ZC3H12A	80149	zinc finger CCCH-type containing 12A	negative regulation of macrophage activation	Biological process	18178554
ZNF488	118738	zinc finger protein 488	protein binding	Molecular function	16713569
PRCP	5547	prolylcarboxypeptidase (angiotensinase C)	blood coagulation	Biological process	-
ERCC2	2068	excision repair cross-complementation group 2	protein C-terminus binding	Molecular function	10801852
LIMD1	8994	LIM domains containing 1	transcription corepressor activity	Molecular function	-
AHCY	191	adenosylhomocysteinase	one-carbon metabolic process	Biological process	-
MYH10	4628	myosin, heavy chain 10, non-muscle	small GTPase mediated signal transduction	Biological process	-
TNFRSF18	8784	tumor necrosis factor receptor superfamily, member 18	apoptotic process	Biological process	-
TGFBR2	7048	transforming growth factor, beta receptor II (70/80kDa)	response to glucose	Biological process	-
ATM	472	ATM serine/threonine kinase	histone mRNA catabolic process	Biological process	16086026
RAB11A	8766	RAB11A, member RAS oncogene family	recycling endosome membrane	Cellular component	-
CKAP5	9793	cytoskeleton associated protein 5	spindle organization	Biological process	14718566
OXA1L	5018	oxidase (cytochrome c) assembly 1-like	mitochondrial respiratory chain	Cellular component	9247084
DAB2IP	153090	DAB2 interacting protein	negative regulation of toll-like receptor 4 signaling pathway	Biological process	19948740
BRCA1	672	breast cancer 1, early onset	positive regulation of transcription from RNA polymerase II promoter	Biological process	20820192
RNF170	81790	ring finger protein 170	integral component of membrane	Cellular component	-
SEC14L3	266629	SEC14-like 3 (S. cerevisiae)	transport	Biological process	-
TNFSF4	7292	tumor necrosis factor (ligand) superfamily, member 4	T cell proliferation	Biological process	-
TSPAN17	26262	tetraspanin 17	ubiquitin-protein transferase activity	Molecular function	10531035
OR5T3	390154	olfactory receptor, family 5, subfamily T, member 3	olfactory receptor activity	Molecular function	-
PLEC	5339	plectin	cytoplasm	Cellular component	-
WDR35	57539	WD repeat domain 35	ciliary basal body	Cellular component	-
HDAC1	3065	histone deacetylase 1	negative regulation by host of viral transcription	Biological process	16540471
MED17	9440	mediator complex subunit 17	positive regulation of transcription, DNA-templated	Biological process	10198638
SDCBP	6386	syndecan binding protein (syntenin)	cytosol	Cellular component	-
IGKV3-20	28912	immunoglobulin kappa variable 3-20	secretory IgA immunoglobulin complex	Cellular component	23250751
STXBP1	6812	syntaxin binding protein 1	protein complex	Cellular component	-
JUN	3725	jun proto-oncogene	protein binding	Molecular function	10327051
RAB3B	5865	RAB3B, member RAS oncogene family	perinuclear region of cytoplasm	Cellular component	19717423
IFT172	26160	intraflagellar transport 172	intraciliary transport particle B	Cellular component	-
PAPPA2	60676	pappalysin 2	cell differentiation	Biological process	-
AKTIP	64400	AKT interacting protein	nucleolus	Cellular component	-
ENPP2	5168	ectonucleotide pyrophosphatase/phosphodiesterase 2	phosphatidylcholine catabolic process	Biological process	21240271
DEFB123	245936	defensin, beta 123	innate immune response	Biological process	-
KCNK4	50801	potassium channel, two pore domain subfamily K, member 4	plasma membrane	Cellular component	-
ABCA12	26154	ATP-binding cassette, sub-family A (ABC1), member 12	protein localization to plasma membrane	Biological process	23931754
ATRX	546	alpha thalassemia/mental retardation syndrome X-linked	DNA translocase activity	Molecular function	12953102
MAPK1	5594	mitogen-activated protein kinase 1	regulation of Golgi inheritance	Biological process	19565474
TFAP2A	7020	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	embryonic body morphogenesis	Biological process	-
ANKRD13C	81573	ankyrin repeat domain 13C	receptor binding	Molecular function	20959461
NPHS2	7827	nephrosis 2, idiopathic, steroid-resistant (podocin)	actin cytoskeleton reorganization	Biological process	17675666
FAS	355	Fas cell surface death receptor	signal transducer activity	Molecular function	10875918
NGF	4803	nerve growth factor (beta polypeptide)	regulation of neuron differentiation	Biological process	-
CDH4	1002	cadherin 4, type 1, R-cadherin (retinal)	cell-cell junction organization	Biological process	-
BTF3	689	basic transcription factor 3	cytoplasm	Cellular component	-
TEC	7006	tec protein tyrosine kinase	cell differentiation	Biological process	-
USP3	9960	ubiquitin specific peptidase 3	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological process	-
PKP4	8502	plakophilin 4	midbody	Cellular component	22965878
CTNS	1497	cystinosin, lysosomal cystine transporter	intracellular membrane-bounded organelle	Cellular component	-
ABCC11	85320	ATP-binding cassette, sub-family C (CFTR/MRP), member 11	metabolic process	Biological process	-
NPNT	255743	nephronectin	positive regulation of transforming growth factor beta receptor signaling pathway	Biological process	-
CLN3	1201	ceroid-lipofuscinosis, neuronal 3	action potential	Biological process	-
PRKCA	5578	protein kinase C, alpha	platelet activation	Biological process	-
GLRA2	2742	glycine receptor, alpha 2	cell junction	Cellular component	-
OPRM1	4988	opioid receptor, mu 1	filamin binding	Molecular function	-
RPS5	6193	ribosomal protein S5	mRNA binding	Molecular function	18464793
MDM4	4194	MDM4, p53 regulator	negative regulation of transcription from RNA polymerase II promoter	Biological process	9226370
MAD1L1	8379	MAD1 mitotic arrest deficient-like 1 (yeast)	cytosol	Cellular component	-
TSC2	7249	tuberous sclerosis 2	14-3-3 protein binding	Molecular function	-
SOX9	6662	SRY (sex determining region Y)-box 9	signal transduction	Biological process	-
CACNG8	59283	calcium channel, voltage-dependent, gamma subunit 8	voltage-gated calcium channel activity	Molecular function	11170751
HIC1	3090	hypermethylated in cancer 1	Wnt signaling pathway	Biological process	-
NUP160	23279	nucleoporin 160kDa	transmembrane transport	Biological process	-
NEDD9	4739	neural precursor cell expressed, developmentally down-regulated 9	cell adhesion	Biological process	-
SIX3	6496	SIX homeobox 3	pituitary gland development	Biological process	-
NR1H4	9971	nuclear receptor subfamily 1, group H, member 4	retinoid X receptor binding	Molecular function	-
PAPL	390928	iron/zinc purple acid phosphatase-like protein	extracellular region	Cellular component	-
CMKLR1	1240	chemerin chemokine-like receptor 1	negative regulation of interleukin-12 production	Biological process	-
MUC3A	4584	mucin 3A, cell surface associated	extracellular matrix constituent, lubricant activity	Molecular function	9334251
SLC22A5	6584	solute carrier family 22 (organic cation/carnitine transporter), member 5	plasma membrane	Cellular component	-
PAX7	5081	paired box 7	sequence-specific DNA binding transcription factor activity	Molecular function	9339373
CDK4	1019	cyclin-dependent kinase 4	response to hyperoxia	Biological process	-
FXYD2	486	FXYD domain containing ion transport regulator 2	sodium:potassium-exchanging ATPase complex	Cellular component	-
PCDHB6	56130	protocadherin beta 6	integral component of plasma membrane	Cellular component	10380929
PACSIN3	29763	protein kinase C and casein kinase substrate in neurons 3	cytoskeletal protein binding	Molecular function	-
RDX	5962	radixin	positive regulation of early endosome to late endosome transport	Biological process	21148287
CHIC2	26511	cysteine-rich hydrophobic domain 2	intracellular	Cellular component	-
STK32B	55351	serine/threonine kinase 32B	ATP binding	Molecular function	-
HES1	3280	hes family bHLH transcription factor 1	negative regulation of pro-B cell differentiation	Biological process	12032823
P3H1	64175	prolyl 3-hydroxylase 1	extracellular matrix organization	Biological process	-
IGHV1OR15-1	388077	immunoglobulin heavy variable 1/OR15-1 (non-functional)	antigen binding	Molecular function	2841108
KAZALD1	81621	Kazal-type serine peptidase inhibitor domain 1	insulin-like growth factor binding	Molecular function	-
RNF128	79589	ring finger protein 128, E3 ubiquitin protein ligase	ubiquitin-protein transferase activity	Molecular function	-
KCNJ18	100134444	potassium channel, inwardly rectifying subfamily J, member 18	potassium ion transmembrane transport	Biological process	-
LTV1	84946	LTV1 ribosome biogenesis factor	cytoplasm	Cellular component	-
FKBP3	2287	FK506 binding protein 3, 25kDa	FK506 binding	Molecular function	1374240
ZNF691	51058	zinc finger protein 691	nucleus	Cellular component	-
NCBP2L	392517	nuclear cap binding protein subunit 2-like	nucleotide binding	Molecular function	-
SUDS3	64426	suppressor of defective silencing 3 homolog (S. cerevisiae)	cytoplasm	Cellular component	-
RNF130	55819	ring finger protein 130	programmed cell death	Biological process	13679316
FBXL6	26233	F-box and leucine-rich repeat protein 6	ubiquitin-protein transferase activity	Molecular function	10531035
CAPN3	825	calpain 3, (p94)	muscle cell cellular homeostasis	Biological process	19386580
CHN1	1123	chimerin 1	cytosol	Cellular component	-
NIN	51199	ninein (GSK3B interacting protein)	centriole	Cellular component	-
DNALI1	7802	dynein, axonemal, light intermediate chain 1	protein binding	Molecular function	15383276
TBCD	6904	tubulin folding cofactor D	microtubule	Cellular component	8706133
CDH23	64072	cadherin-related 23	photoreceptor cell maintenance	Biological process	16679490
UPF3B	65109	UPF3 regulator of nonsense transcripts homolog B (yeast)	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Biological process	-
C16orf58	64755	chromosome 16 open reading frame 58	integral component of membrane	Cellular component	-
GRIN3A	116443	glutamate receptor, ionotropic, N-methyl-D-aspartate 3A	plasma membrane	Cellular component	-
GATA4	2626	GATA binding protein 4	cardiac muscle hypertrophy in response to stress	Biological process	-
RHBDL1	9028	rhomboid, veinlet-like 1 (Drosophila)	integral component of plasma membrane	Cellular component	9662444
DCTN2	10540	dynactin 2 (p50)	extracellular exosome	Cellular component	19056867
RRH	10692	retinal pigment epithelium-derived rhodopsin homolog	photoreceptor activity	Molecular function	-
ZFP91	80829	ZFP91 zinc finger protein	metal ion binding	Molecular function	-
RTN4RL2	349667	reticulon 4 receptor-like 2	extracellular exosome	Cellular component	23376485
PKD2L1	9033	polycystic kidney disease 2-like 1	muscle alpha-actinin binding	Molecular function	17944866
NUP93	9688	nucleoporin 93kDa	viral process	Biological process	-
PRKD1	5587	protein kinase D1	angiogenesis	Biological process	-
CD2BP2	10421	CD2 (cytoplasmic tail) binding protein 2	gene expression	Biological process	-
RDH13	112724	retinol dehydrogenase 13 (all-trans/9-cis)	oxidation-reduction process	Biological process	-
CELSR1	9620	cadherin, EGF LAG seven-pass G-type receptor 1	planar cell polarity pathway involved in neural tube closure	Biological process	-
ZNF146	7705	zinc finger protein 146	cytoplasm	Cellular component	-
CAV1	857	caveolin 1, caveolae protein, 22kDa	positive regulation of ER-associated ubiquitin-dependent protein catabolic process	Biological process	24089527
MT4	84560	metallothionein 4	cell	Cellular component	-
FGFR1	2260	fibroblast growth factor receptor 1	regulation of lateral mesodermal cell fate specification	Biological process	-
PRAMEF5	343068	PRAME family member 5	positive regulation of cell proliferation	Biological process	-
ZNF688	146542	zinc finger protein 688	biological_process	Biological process	-
RAC2	5880	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	blood coagulation	Biological process	-
GCNT6	644378	glucosaminyl (N-acetyl) transferase 6	Golgi membrane	Cellular component	-
MRO	83876	maestro	nucleolus	Cellular component	-
HELQ	113510	helicase, POLQ-like	double-strand break repair via homologous recombination	Biological process	19995904
PALM3	342979	paralemmin 3	negative regulation of cytokine-mediated signaling pathway	Biological process	21187075
WNT1	7471	wingless-type MMTV integration site family, member 1	neuron fate determination	Biological process	-
DALRD3	55152	DALR anticodon binding domain containing 3	ATP binding	Molecular function	-
FERD3L	222894	Fer3-like bHLH transcription factor	nucleus	Cellular component	-
DERL1	79139	derlin 1	VCP-NPL4-UFD1 AAA ATPase complex	Cellular component	16186510
TAF9	6880	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa	histone acetyltransferase activity	Molecular function	11564863
SLC39A7	7922	solute carrier family 39 (zinc transporter), member 7	protein binding	Molecular function	22317921
MALT1	10892	MALT1 paracaspase	Fc-epsilon receptor signaling pathway	Biological process	-
ATP5O	539	ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit	transporter activity	Molecular function	7490082
SERPINE2	5270	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2	neuromuscular junction	Cellular component	2037625
IKBKE	9641	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	toll-like receptor 3 signaling pathway	Biological process	-
ADPRH	141	ADP-ribosylarginine hydrolase	protein binding	Molecular function	25416956
CARD9	64170	caspase recruitment domain family, member 9	regulation of apoptotic process	Biological process	-
INSC	387755	inscuteable homolog (Drosophila)	lung epithelial cell differentiation	Biological process	-
TEX11	56159	testis expressed 11	male meiosis chromosome segregation	Biological process	-
ADNP2	22850	ADNP homeobox 2	neuron differentiation	Biological process	-
GZMK	3003	granzyme K (granzyme 3; tryptase II)	serine-type endopeptidase activity	Molecular function	-
OBP2A	29991	odorant binding protein 2A	odorant binding	Molecular function	10607840
IKBKG	8517	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	TRIF-dependent toll-like receptor signaling pathway	Biological process	-
ZNF837	116412	zinc finger protein 837	nucleus	Cellular component	-
PFKL	5211	phosphofructokinase, liver	protein oligomerization	Biological process	6444721
WAS	7454	Wiskott-Aldrich syndrome	cytosol	Cellular component	-
MYC	4609	v-myc avian myelocytomatosis viral oncogene homolog	energy reserve metabolic process	Biological process	9924025
YIPF4	84272	Yip1 domain family, member 4	plasma membrane	Cellular component	-
RIPK1	8737	receptor (TNFRSF)-interacting serine-threonine kinase 1	programmed necrotic cell death	Biological process	-
DDRGK1	65992	DDRGK domain containing 1	ubiquitin-like protein ligase binding	Molecular function	25219498
TCF3	6929	transcription factor 3	transcription coactivator activity	Molecular function	14752053
TK2	7084	thymidine kinase 2, mitochondrial	DNA biosynthetic process	Biological process	-
XRCC1	7515	X-ray repair complementing defective repair in Chinese hamster cells 1	protein binding	Molecular function	14755728
MKL2	57496	MKL/myocardin-like 2	in utero embryonic development	Biological process	-
ANKRD2	26287	ankyrin repeat domain 2 (stretch responsive muscle)	euchromatin	Cellular component	-
ZNF573	126231	zinc finger protein 573	metal ion binding	Molecular function	-
REEP5	7905	receptor accessory protein 5	protein binding	Molecular function	16762630
API5	8539	apoptosis inhibitor 5	spliceosomal complex	Cellular component	11555636
TNFAIP3	7128	tumor necrosis factor, alpha-induced protein 3	negative regulation of interleukin-1 beta production	Biological process	-
SVIP	258010	small VCP/p97-interacting protein	positive regulation of protein lipidation	Biological process	21909394
YTHDF1	54915	YTH N(6)-methyladenosine RNA binding protein 1	poly(A) RNA binding	Molecular function	22658674
GTF2H3	2967	general transcription factor IIH, polypeptide 3, 34kDa	transcription elongation from RNA polymerase II promoter	Biological process	-
TNN	63923	tenascin N	cell migration	Biological process	-
ZIM3	114026	zinc finger, imprinted 3	nucleus	Cellular component	-
RARRES2	5919	retinoic acid receptor responder (tazarotene induced) 2	receptor binding	Molecular function	14530373
SRC	6714	SRC proto-oncogene, non-receptor tyrosine kinase	Ras protein signal transduction	Biological process	-
GNA14	9630	guanine nucleotide binding protein (G protein), alpha 14	heterotrimeric G-protein complex	Cellular component	1946421
TFIP11	24144	tuftelin interacting protein 11	DNA binding	Molecular function	-
FAU	2197	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Biological process	-
HSPB1	3315	heat shock 27kDa protein 1	positive regulation of angiogenesis	Biological process	18440775
NECAB1	64168	N-terminal EF-hand calcium binding protein 1	calcium ion binding	Molecular function	-
DNASE1L1	1774	deoxyribonuclease I-like 1	DNA catabolic process, endonucleolytic	Biological process	-
SIAH3	283514	siah E3 ubiquitin protein ligase family member 3	nucleus	Cellular component	-
SLC25A23	79085	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23	regulation of oxidative phosphorylation	Biological process	-
KSR1	8844	kinase suppressor of ras 1	protein complex	Cellular component	22572157
DMRT1	1761	doublesex and mab-3 related transcription factor 1	Sertoli cell development	Biological process	-
BAIAP2L1	55971	BAI1-associated protein 2-like 1	plasma membrane organization	Biological process	-
ZNF567	163081	zinc finger protein 567	nucleus	Cellular component	-
UCHL3	7347	ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)	protein deubiquitination	Biological process	-
PHF12	57649	PHD finger protein 12	phosphatidylinositol binding	Molecular function	16893883
CCKBR	887	cholecystokinin B receptor	sensory perception	Biological process	7681836
STAB2	55576	stabilin 2	external side of plasma membrane	Cellular component	-
PRDX5	25824	peroxiredoxin 5	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	18262354
AGT	183	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	positive regulation of superoxide anion generation	Biological process	-
APPL1	26060	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	insulin receptor signaling pathway	Biological process	17848569
GUSB	2990	glucuronidase, beta	membrane	Cellular component	19946888
FECH	2235	ferrochelatase	heme biosynthetic process	Biological process	-
CALR	811	calreticulin	proteinaceous extracellular matrix	Cellular component	-
SPZ1	84654	spermatogenic leucine zipper 1	protein binding	Molecular function	25416956
SAR1A	56681	secretion associated, Ras related GTPase 1A	Golgi apparatus	Cellular component	-
GABRG2	2566	gamma-aminobutyric acid (GABA) A receptor, gamma 2	protein binding	Molecular function	9892355
MYL12A	10627	myosin, light chain 12A, regulatory, non-sarcomeric	calcium ion binding	Molecular function	-
CACNA2D1	781	calcium channel, voltage-dependent, alpha 2/delta subunit 1	T-tubule	Cellular component	-
ASL	435	argininosuccinate lyase	internal protein amino acid acetylation	Biological process	20167786
WNT1	7471	wingless-type MMTV integration site family, member 1	negative regulation of transforming growth factor beta receptor signaling pathway	Biological process	-
VCAM1	7412	vascular cell adhesion molecule 1	extracellular space	Cellular component	9290466
FCN3	8547	ficolin (collagen/fibrinogen domain containing) 3	complement activation	Biological process	-
SSH2	85464	slingshot protein phosphatase 2	regulation of lamellipodium assembly	Biological process	-
CHMP2B	25978	charged multivesicular body protein 2B	protein binding	Molecular function	21975012
ZNF622	90441	zinc finger protein 622	positive regulation of apoptotic process	Biological process	21771788
TYRO3	7301	TYRO3 protein tyrosine kinase	peptidyl-tyrosine phosphorylation	Biological process	7511603
C2CD4A	145741	C2 calcium-dependent domain containing 4A	calcium ion binding	Molecular function	-
F7	2155	coagulation factor VII (serum prothrombin conversion accelerator)	organ regeneration	Biological process	-
PDK2	5164	pyruvate dehydrogenase kinase, isozyme 2	protein homodimerization activity	Molecular function	19833728
DNM1L	10059	dynamin 1-like	microtubule	Cellular component	21525035
RASSF1	11186	Ras association (RalGDS/AF-6) domain family member 1	nucleus	Cellular component	14743218
RNF180	285671	ring finger protein 180	protein polyubiquitination	Biological process	-
CD14	929	CD14 molecule	lipoteichoic acid binding	Molecular function	12594207
IHH	3549	indian hedgehog	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
VPS4B	9525	vacuolar protein sorting 4 homolog B (S. cerevisiae)	centrosome	Cellular component	20616062
TRIM68	55128	tripartite motif containing 68	nucleoplasm	Cellular component	-
IFNA6	3443	interferon, alpha 6	blood coagulation	Biological process	-
LAMA5	3911	laminin, alpha 5	cell proliferation	Biological process	11821406
KIF4B	285643	kinesin family member 4B	antigen processing and presentation of exogenous peptide antigen via MHC class II	Biological process	-
KIF2A	3796	kinesin heavy chain member 2A	ATP binding	Molecular function	-
SOX9	6662	SRY (sex determining region Y)-box 9	positive regulation of extracellular matrix assembly	Biological process	-
F11R	50848	F11 receptor	response to radiation	Biological process	-
TUBB2A	7280	tubulin, beta 2A class IIa	protein folding	Biological process	-
KRT19	3880	keratin 19, type I	cell differentiation involved in embryonic placenta development	Biological process	-
CDKN2B	1030	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	cellular response to nutrient	Biological process	17597576
HSD17B1	3292	hydroxysteroid (17-beta) dehydrogenase 1	small molecule metabolic process	Biological process	-
CCR9	10803	chemokine (C-C motif) receptor 9	integral component of plasma membrane	Cellular component	10229797
GP6	51206	glycoprotein VI (platelet)	collagen binding	Molecular function	11027634
ROCK1	6093	Rho-associated, coiled-coil containing protein kinase 1	negative regulation of protein binding	Biological process	18573880
THOC1	9984	THO complex 1	positive regulation of DNA-templated transcription, elongation	Biological process	22144908
CDH18	1016	cadherin 18, type 2	adherens junction organization	Biological process	-
SLC44A4	80736	solute carrier family 44, member 4	acetylcholine biosynthetic process	Biological process	23651124
GRIK1	2897	glutamate receptor, ionotropic, kainate 1	regulation of inhibitory postsynaptic membrane potential	Biological process	-
PROX1	5629	prospero homeobox 1	regulation of circadian rhythm	Biological process	23723244
AKAP13	11214	A kinase (PRKA) anchor protein 13	protein complex scaffold	Molecular function	-
AKT2	208	v-akt murine thymoma viral oncogene homolog 2	positive regulation of fatty acid beta-oxidation	Biological process	16814735
FKBP1B	2281	FK506 binding protein 1B, 12.6 kDa	'de novo' protein folding	Biological process	11322937
APP	351	amyloid beta (A4) precursor protein	regulation of multicellular organism growth	Biological process	-
PARPBP	55010	PARP1 binding protein	chromatin	Cellular component	22153967
ACTB	60	actin, beta	membrane	Cellular component	19946888
PLCB1	23236	phospholipase C, beta 1 (phosphoinositide-specific)	insulin-like growth factor receptor signaling pathway	Biological process	-
DGKQ	1609	diacylglycerol kinase, theta 110kDa	thrombin receptor signaling pathway	Biological process	15632189
EDARADD	128178	EDAR-associated death domain	odontogenesis of dentin-containing tooth	Biological process	-
OR52B6	340980	olfactory receptor, family 52, subfamily B, member 6	olfactory receptor activity	Molecular function	-
MTG2	26164	mitochondrial ribosome-associated GTPase 2	mitochondrial matrix	Cellular component	23396448
DDX51	317781	DEAD (Asp-Glu-Ala-Asp) box polypeptide 51	poly(A) RNA binding	Molecular function	22658674
MYL6	4637	myosin, light chain 6, alkali, smooth muscle and non-muscle	myosin complex	Cellular component	2304459
ASIC2	40	acid sensing (proton gated) ion channel 2	protein localization to synapse	Biological process	-
HACD3	51495	3-hydroxyacyl-CoA dehydratase 3	small GTPase mediated signal transduction	Biological process	10747961
OTUD4	54726	OTU deubiquitinase 4	protein binding	Molecular function	25416956
ZNF584	201514	zinc finger protein 584	transcription, DNA-templated	Biological process	-
IGF1R	3480	insulin-like growth factor 1 receptor	protein tyrosine kinase activity	Molecular function	-
OSBPL5	114879	oxysterol binding protein-like 5	membrane	Cellular component	19946888
ATOH1	474	atonal homolog 1 (Drosophila)	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	-
DNAJC21	134218	DnaJ (Hsp40) homolog, subfamily C, member 21	poly(A) RNA binding	Molecular function	22658674
LPCAT2	54947	lysophosphatidylcholine acyltransferase 2	phospholipid metabolic process	Biological process	-
SRSF12	135295	serine/arginine-rich splicing factor 12	nucleoplasm	Cellular component	11684676
RPLP0	6175	ribosomal protein, large, P0	translational initiation	Biological process	-
SF3A1	10291	splicing factor 3a, subunit 1, 120kDa	poly(A) RNA binding	Molecular function	22658674
RASSF7	8045	Ras association (RalGDS/AF-6) domain family (N-terminal) member 7	cytoplasm	Cellular component	-
CFAP221	200373	cilia and flagella associated protein 221	cilium	Cellular component	-
CCNB2	9133	cyclin B2	thymus development	Biological process	-
NARS2	79731	asparaginyl-tRNA synthetase 2, mitochondrial (putative)	asparagine-tRNA ligase activity	Molecular function	-
EIF4G1	1981	eukaryotic translation initiation factor 4 gamma, 1	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Biological process	-
GJA5	2702	gap junction protein, alpha 5, 40kDa	negative regulation of blood pressure	Biological process	-
RBM18	92400	RNA binding motif protein 18	RNA binding	Molecular function	-
NLGN1	22871	neuroligin 1	positive regulation of synaptic transmission, GABAergic	Biological process	-
KEAP1	9817	kelch-like ECH-associated protein 1	cellular response to interleukin-4	Biological process	-
SFTPA2	729238	surfactant protein A2	proteinaceous extracellular matrix	Cellular component	-
PRCP	5547	prolylcarboxypeptidase (angiotensinase C)	plasma kallikrein-kinin cascade	Biological process	-
XBP1	7494	X-box binding protein 1	negative regulation of transcription from RNA polymerase II promoter	Biological process	16461360
ZNF280C	55609	zinc finger protein 280C	transcription from RNA polymerase II promoter	Biological process	-
ABCA5	23461	ATP-binding cassette, sub-family A (ABC1), member 5	integral component of membrane	Cellular component	-
DBT	1629	dihydrolipoamide branched chain transacylase E2	ubiquitin protein ligase binding	Molecular function	19725078
LAT	27040	linker for activation of T cells	positive regulation of signal transduction	Biological process	9489702
UGT1A10	54575	UDP glucuronosyltransferase 1 family, polypeptide A10	flavonoid glucuronidation	Biological process	-
TMEM79	84283	transmembrane protein 79	positive regulation of epidermis development	Biological process	-
POLD4	57804	polymerase (DNA-directed), delta 4, accessory subunit	DNA strand elongation involved in DNA replication	Biological process	-
CYP4F12	66002	cytochrome P450, family 4, subfamily F, polypeptide 12	sodium ion homeostasis	Biological process	-
TNIP2	79155	TNFAIP3 interacting protein 2	toll-like receptor 9 signaling pathway	Biological process	-
AGFG2	3268	ArfGAP with FG repeats 2	molecular_function	Molecular function	-
TAF10	6881	TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa	nucleus	Cellular component	-
OR8D2	283160	olfactory receptor, family 8, subfamily D, member 2 (gene/pseudogene)	integral component of plasma membrane	Cellular component	-
PPL	5493	periplakin	desmosome	Cellular component	-
NTRK2	4915	neurotrophic tyrosine kinase, receptor, type 2	central nervous system neuron development	Biological process	-
SMARCE1	6605	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	nervous system development	Biological process	-
ZNF681	148213	zinc finger protein 681	nucleus	Cellular component	-
SPI1	6688	Spi-1 proto-oncogene	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
MUL1	79594	mitochondrial E3 ubiquitin protein ligase 1	regulation of mitochondrion organization	Biological process	24898855
TRIM32	22954	tripartite motif containing 32	nucleus	Cellular component	-
EFNB3	1949	ephrin-B3	axon choice point recognition	Biological process	-
EDDM3B	64184	epididymal protein 3B	molecular_function	Molecular function	-
IGLON5	402665	IgLON family member 5	regulation of neurogenesis	Biological process	-
EFNB3	1949	ephrin-B3	integral component of plasma membrane	Cellular component	9126477
ABLIM2	84448	actin binding LIM protein family, member 2	actin binding	Molecular function	-
ADIPOQ	9370	adiponectin, C1Q and collagen domain containing	protein homodimerization activity	Molecular function	12021245
PTPN23	25930	protein tyrosine phosphatase, non-receptor type 23	nucleus	Cellular component	21179510
TOR2A	27433	torsin family 2, member A	hormone activity	Molecular function	-
NADK2	133686	NAD kinase 2, mitochondrial	NAD+ kinase activity	Molecular function	23212377
TBC1D3F	84218	TBC1 domain family, member 3F	positive regulation of GTPase activity	Biological process	-
ACPP	55	acid phosphatase, prostate	acid phosphatase activity	Molecular function	8132635
STAT2	6773	signal transducer and activator of transcription 2, 113kDa	cytokine-mediated signaling pathway	Biological process	-
PAM	5066	peptidylglycine alpha-amidating monooxygenase	oxidation-reduction process	Biological process	-
CDH11	1009	cadherin 11, type 2, OB-cadherin (osteoblast)	integral component of membrane	Cellular component	-
TAF13	6884	TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa	protein binding	Molecular function	11438666
ZNF18	7566	zinc finger protein 18	protein binding	Molecular function	21516116
NRG3	10718	neuregulin 3	mammary placode formation	Biological process	-
SIAH2	6478	siah E3 ubiquitin protein ligase 2	negative regulation of extrinsic apoptotic signaling pathway	Biological process	21586138
HYAL2	8692	hyaluronoglucosaminidase 2	glycosaminoglycan catabolic process	Biological process	9712871
PRAMEF12	390999	PRAME family member 12	negative regulation of retinoic acid receptor signaling pathway	Biological process	-
PLCB4	5332	phospholipase C, beta 4	postsynaptic density	Cellular component	-
SAA4	6291	serum amyloid A4, constitutive	chemoattractant activity	Molecular function	-
SQRDL	58472	sulfide quinone reductase-like (yeast)	sulfur amino acid metabolic process	Biological process	-
WT1	7490	Wilms tumor 1	mesenchymal to epithelial transition	Biological process	-
HTT	3064	huntingtin	urea cycle	Biological process	-
GFY	100507003	golgi-associated, olfactory signaling regulator	protein localization to nonmotile primary cilium	Biological process	-
SFN	2810	stratifin	regulation of cyclin-dependent protein serine/threonine kinase activity	Biological process	-
DMRTB1	63948	DMRT-like family B with proline-rich C-terminal, 1	transcription, DNA-templated	Biological process	-
ISG20	3669	interferon stimulated exonuclease gene 20kDa	defense response to virus	Biological process	21036379
VAV2	7410	vav 2 guanine nucleotide exchange factor	signal transduction	Biological process	7762982
KLHL14	57565	kelch-like family member 14	endoplasmic reticulum	Cellular component	19535332
PRAMEF8	391002	PRAME family member 8	negative regulation of retinoic acid receptor signaling pathway	Biological process	-
WT1	7490	Wilms tumor 1	metanephric epithelium development	Biological process	7856737
SERPINB4	6318	serpin peptidase inhibitor, clade B (ovalbumin), member 4	negative regulation of peptidase activity	Biological process	12949073
MAST1	22983	microtubule associated serine/threonine kinase 1	cytoskeleton organization	Biological process	-
CPQ	10404	carboxypeptidase Q	protein homodimerization activity	Molecular function	12675526
DUSP1	1843	dual specificity phosphatase 1	peptidyl-threonine dephosphorylation	Biological process	-
NANOGP8	388112	Nanog homeobox pseudogene 8	nucleus	Cellular component	-
ZNF778	197320	zinc finger protein 778	DNA binding	Molecular function	-
PLD1	5337	phospholipase D1, phosphatidylcholine-specific	glycerophospholipid biosynthetic process	Biological process	-
CA12	771	carbonic anhydrase XII	one-carbon metabolic process	Biological process	-
CAPN10	11132	calpain 10	cellular component disassembly involved in execution phase of apoptosis	Biological process	-
TAS2R16	50833	taste receptor, type 2, member 16	plasma membrane	Cellular component	-
BDNF	627	brain-derived neurotrophic factor	cytoplasmic membrane-bounded vesicle	Cellular component	-
SLU7	10569	SLU7 splicing factor homolog (S. cerevisiae)	cellular response to heat	Biological process	21122810
CCL1	6346	chemokine (C-C motif) ligand 1	chemotaxis	Biological process	9417093
COL5A3	50509	collagen, type V, alpha 3	extracellular matrix disassembly	Biological process	-
GUCY2C	2984	guanylate cyclase 2C	regulation of cell proliferation	Biological process	-
CDH1	999	cadherin 1, type 1, E-cadherin (epithelial)	single organismal cell-cell adhesion	Biological process	16338932
ADCY5	111	adenylate cyclase 5	transmembrane transport	Biological process	-
ZFR	51663	zinc finger RNA binding protein	chromosome	Cellular component	-
RPS17	6218	ribosomal protein S17	SRP-dependent cotranslational protein targeting to membrane	Biological process	-
HPSE	10855	heparanase	membrane raft	Cellular component	-
UBE2N	7334	ubiquitin-conjugating enzyme E2N	UBC13-MMS2 complex	Cellular component	16129784
NOD2	64127	nucleotide-binding oligomerization domain containing 2	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	Biological process	-
PML	5371	promyelocytic leukemia	maintenance of protein location in nucleus	Biological process	17332504
KIF5A	3798	kinesin family member 5A	synaptic transmission	Biological process	7514426
RBM8A	9939	RNA binding motif protein 8A	mRNA export from nucleus	Biological process	-
CX3CR1	1524	chemokine (C-X3-C motif) receptor 1	cell adhesion	Biological process	-
BCL2L11	10018	BCL2-like 11 (apoptosis facilitator)	positive regulation of mitochondrial membrane permeability involved in apoptotic process	Biological process	-
JMY	133746	junction mediating and regulatory protein, p53 cofactor	plasma membrane	Cellular component	-
RPL27A	6157	ribosomal protein L27a	membrane	Cellular component	19946888
COBL	23242	cordon-bleu WH2 repeat protein	embryonic axis specification	Biological process	-
TIMELESS	8914	timeless circadian clock	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
KRT72	140807	keratin 72, type II	biological_process	Biological process	-
FNTB	2342	farnesyltransferase, CAAX box, beta	protein farnesyltransferase activity	Molecular function	19228685
STXBP6	29091	syntaxin binding protein 6 (amisyn)	negative regulation of exocytosis	Biological process	15217342
AKT1S1	84335	AKT1 substrate 1 (proline-rich)	Fc-epsilon receptor signaling pathway	Biological process	-
OR4Q3	441669	olfactory receptor, family 4, subfamily Q, member 3	G-protein coupled receptor activity	Molecular function	-
OGFOD1	55239	2-oxoglutarate and iron-dependent oxygenase domain containing 1	cytoplasmic stress granule	Cellular component	24550447
LRP6	4040	low density lipoprotein receptor-related protein 6	canonical Wnt signaling pathway involved in neural crest cell differentiation	Biological process	11029007
MED24	9862	mediator complex subunit 24	intracellular steroid hormone receptor signaling pathway	Biological process	11867769
LARP4	113251	La ribonucleoprotein domain family, member 4	poly(A) RNA binding	Molecular function	22658674
RCC2	55920	regulator of chromosome condensation 2	chromosome passenger complex localization to kinetochore	Biological process	12919680
THBS1	7057	thrombospondin 1	collagen V binding	Molecular function	6693501
ITSN2	50618	intersectin 2	positive regulation of dendrite extension	Biological process	23999003
OR2T3	343173	olfactory receptor, family 2, subfamily T, member 3	integral component of membrane	Cellular component	-
HMGB1	3146	high mobility group box 1	DNA topological change	Biological process	-
AXIN1	8312	axin 1	optic placode formation	Biological process	-
ALDH8A1	64577	aldehyde dehydrogenase 8 family, member A1	9-cis-retinoic acid biosynthetic process	Biological process	-
SUPT5H	6829	suppressor of Ty 5 homolog (S. cerevisiae)	positive regulation of viral transcription	Biological process	-
HMGN3	9324	high mobility group nucleosomal binding domain 3	chromatin	Cellular component	-
PDLIM7	9260	PDZ and LIM domain 7 (enigma)	focal adhesion	Cellular component	-
CD99L2	83692	CD99 molecule-like 2	integral component of membrane	Cellular component	-
SGMS1	259230	sphingomyelin synthase 1	sphingolipid metabolic process	Biological process	-
C5	727	complement component 5	protein binding	Molecular function	21217642
NID1	4811	nidogen 1	laminin binding	Molecular function	22952693
PICALM	8301	phosphatidylinositol binding clathrin assembly protein	negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process	Biological process	-
SET	6418	SET nuclear proto-oncogene	negative regulation of neuron apoptotic process	Biological process	18374643
SPDYE4	388333	speedy/RINGO cell cycle regulator family member E4	protein kinase binding	Molecular function	-
P2RY4	5030	pyrimidinergic receptor P2Y, G-protein coupled, 4	positive regulation of cytosolic calcium ion concentration	Biological process	8537335
TRABD2A	129293	TraB domain containing 2A	Wnt signaling pathway	Biological process	-
PCSK9	255738	proprotein convertase subtilisin/kexin type 9	low-density lipoprotein particle receptor binding	Molecular function	17452316
PMAIP1	5366	phorbol-12-myristate-13-acetate-induced protein 1	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	14699081
GNAI3	2773	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3	transport	Biological process	2452165
CENPV	201161	centromere protein V	ameboidal-type cell migration	Biological process	19930468
PTGDS	5730	prostaglandin D2 synthase 21kDa (brain)	endoplasmic reticulum membrane	Cellular component	-
NODAL	4838	nodal growth differentiation factor	negative regulation of cell development	Biological process	-
MVB12A	93343	multivesicular body subunit 12A	protein transport	Biological process	-
ACE2	59272	angiotensin I converting enzyme 2	extracellular exosome	Cellular component	19056867
PFKFB3	5209	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	canonical glycolysis	Biological process	-
BMP1	649	bone morphogenetic protein 1	peptidase activity	Molecular function	12393877
SLC25A26	115286	solute carrier family 25 (S-adenosylmethionine carrier), member 26	mitochondrion	Cellular component	-
CD81	975	CD81 molecule	positive regulation of 1-phosphatidylinositol 4-kinase activity	Biological process	14676841
CSPG5	10675	chondroitin sulfate proteoglycan 5 (neuroglycan C)	small molecule metabolic process	Biological process	-
ADRA2C	152	adrenoceptor alpha 2C	female pregnancy	Biological process	-
EPO	2056	erythropoietin	response to testosterone	Biological process	-
GPX1	2876	glutathione peroxidase 1	blood vessel endothelial cell migration	Biological process	-
ERCC3	2071	excision repair cross-complementation group 3	nucleotide-excision repair, DNA incision	Biological process	17466626
APOBEC3B	9582	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B	innate immune response	Biological process	-
CHMP2A	27243	charged multivesicular body protein 2A	protein transport	Biological process	-
TRIOBP	11078	TRIO and F-actin binding protein	barbed-end actin filament capping	Biological process	11148140
MYL4	4635	myosin, light chain 4, alkali; atrial, embryonic	calcium ion binding	Molecular function	-
KAT6A	7994	K(lysine) acetyltransferase 6A	face morphogenesis	Biological process	-
ZNF391	346157	zinc finger protein 391	metal ion binding	Molecular function	-
DYNC2H1	79659	dynein, cytoplasmic 2, heavy chain 1	embryonic limb morphogenesis	Biological process	-
NDST1	3340	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	[heparan sulfate]-glucosamine N-sulfotransferase activity	Molecular function	-
ADH7	131	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	fatty acid omega-oxidation	Biological process	9600267
GAS8	2622	growth arrest-specific 8	molecular_function	Molecular function	-
UGT2B17	7367	UDP glucuronosyltransferase 2 family, polypeptide B17	endoplasmic reticulum membrane	Cellular component	-
RAMP3	10268	receptor (G protein-coupled) activity modifying protein 3	cellular response to estradiol stimulus	Biological process	-
AOC2	314	amine oxidase, copper containing 2 (retina-specific)	primary amine oxidase activity	Molecular function	-
TSSK1B	83942	testis-specific serine kinase 1B	cytoplasm	Cellular component	-
RPS6KA4	8986	ribosomal protein S6 kinase, 90kDa, polypeptide 4	regulation of transcription, DNA-templated	Biological process	9792677
CALM1	801	calmodulin 1 (phosphorylase kinase, delta)	thioesterase binding	Molecular function	16127172
KMT2E	55904	lysine (K)-specific methyltransferase 2E	histone H3-K4 methylation	Biological process	-
MRE11A	4361	MRE11 meiotic recombination 11 homolog A (S. cerevisiae)	double-strand break repair via nonhomologous end joining	Biological process	9651580
UBB	7314	ubiquitin B	G2/M transition of mitotic cell cycle	Biological process	-
BLNK	29760	B-cell linker	positive regulation of signal transduction	Biological process	9697839
OSR1	130497	odd-skipped related transciption factor 1	positive regulation of epithelial cell proliferation	Biological process	-
PDZK1	5174	PDZ domain containing 1	positive regulation of protein targeting to membrane	Biological process	-
ST3GAL5	8869	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	sialyltransferase activity	Molecular function	10092602
PTGDS	5730	prostaglandin D2 synthase 21kDa (brain)	protein binding	Molecular function	25416956
NTN1	9423	netrin 1	single organismal cell-cell adhesion	Biological process	-
GSTA2	2939	glutathione S-transferase alpha 2	extracellular exosome	Cellular component	23533145
CRACR2B	283229	calcium release activated channel regulator 2B	protein binding	Molecular function	25416956
DCSTAMP	81501	dendrocyte expressed seven transmembrane protein	myeloid dendritic cell differentiation	Biological process	-
TRAP1	10131	TNF receptor-associated protein 1	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	Biological process	17579517
TRIM13	10206	tripartite motif containing 13	positive regulation of NF-kappaB transcription factor activity	Biological process	23077300
FOXF1	2294	forkhead box F1	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
SHROOM1	134549	shroom family member 1	cell morphogenesis	Biological process	16684770
NELFCD	51497	negative elongation factor complex member C/D	NELF complex	Cellular component	12612062
ABCG1	9619	ATP-binding cassette, sub-family G (WHITE), member 1	cholesterol metabolic process	Biological process	15994327
PPARGC1B	133522	peroxisome proliferator-activated receptor gamma, coactivator 1 beta	nucleotide binding	Molecular function	-
CDKN1A	1026	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	Ras protein signal transduction	Biological process	9054499
KCNA1	3736	potassium channel, voltage gated shaker related subfamily A, member 1	cell communication by electrical coupling	Biological process	-
LATS1	9113	large tumor suppressor kinase 1	ATP binding	Molecular function	10518011
BAK1	578	BCL2-antagonist/killer 1	cellular response to UV	Biological process	-
EVL	51466	Enah/Vasp-like	protein homotetramerization	Biological process	-
VPS18	57617	vacuolar protein sorting 18 homolog (S. cerevisiae)	intracellular protein transport	Biological process	-
CAPN2	824	calpain 2, (m/II) large subunit	cysteine-type peptidase activity	Molecular function	2209092
IL4	3565	interleukin 4	growth factor activity	Molecular function	11418631
DRD4	1815	dopamine receptor D4	olfactory learning	Biological process	-
EPHX4	253152	epoxide hydrolase 4	metabolic process	Biological process	-
CPLX2	10814	complexin 2	regulation of exocytosis	Biological process	15217342
MYL12A	10627	myosin, light chain 12A, regulatory, non-sarcomeric	platelet aggregation	Biological process	23382103
SLC34A1	6569	solute carrier family 34 (type II sodium/phosphate cotransporter), member 1	symporter activity	Molecular function	-
IL9	3578	interleukin 9	growth factor activity	Molecular function	-
SIGLEC6	946	sialic acid binding Ig-like lectin 6	protein binding	Molecular function	25416956
CD27	939	CD27 molecule	positive regulation of B cell differentiation	Biological process	10809378
OSR1	130497	odd-skipped related transciption factor 1	metanephric smooth muscle tissue development	Biological process	-
PRKCG	5582	protein kinase C, gamma	perinuclear region of cytoplasm	Cellular component	-
WDR12	55759	WD repeat domain 12	nucleolus	Cellular component	16043514
KIF5A	3798	kinesin family member 5A	small GTPase mediated signal transduction	Biological process	-
VIM	7431	vimentin	protein binding	Molecular function	10852826
PSMD2	5708	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	apoptotic process	Biological process	-
CLU	1191	clusterin	chaperone-mediated protein complex assembly	Biological process	17412999
FOXK2	3607	forkhead box K2	regulation of transcription, DNA-templated	Biological process	12402362
MYLK	4638	myosin light chain kinase	myosin light chain kinase activity	Molecular function	16284075
ACTG2	72	actin, gamma 2, smooth muscle, enteric	lamellipodium	Cellular component	-
IDH1	3417	isocitrate dehydrogenase 1 (NADP+), soluble	cytosol	Cellular component	-
E2F4	1874	E2F transcription factor 4, p107/p130-binding	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	10488129
UTS2	10911	urotensin 2	regulation of blood pressure	Biological process	10499587
ELOVL1	64834	ELOVL fatty acid elongase 1	long-chain fatty-acyl-CoA biosynthetic process	Biological process	-
PDGFD	80310	platelet derived growth factor D	extracellular exosome	Cellular component	23376485
SLC44A4	80736	solute carrier family 44, member 4	transmembrane transport	Biological process	-
ERN1	2081	endoplasmic reticulum to nucleus signaling 1	integral component of endoplasmic reticulum membrane	Cellular component	9637683
AK2	204	adenylate kinase 2	oxidative phosphorylation	Biological process	-
TADA2B	93624	transcriptional adaptor 2B	chromatin organization	Biological process	-
ART1	417	ADP-ribosyltransferase 1	protein ADP-ribosylation	Biological process	-
BPY2C	442868	basic charge, Y-linked, 2C	single fertilization	Biological process	9381176
NOC2L	26155	nucleolar complex associated 2 homolog (S. cerevisiae)	nucleosome binding	Molecular function	16322561
VCAN	1462	versican	cell adhesion	Biological process	-
NAPSA	9476	napsin A aspartic peptidase	alveolar lamellar body	Cellular component	18216060
SLC26A6	65010	solute carrier family 26 (anion exchanger), member 6	formate transport	Biological process	-
ZNF286B	729288	zinc finger protein 286B	transcription, DNA-templated	Biological process	-
SPTBN5	51332	spectrin, beta, non-erythrocytic 5	membrane	Cellular component	10764729
IGF1R	3480	insulin-like growth factor 1 receptor	protein binding	Molecular function	10026153
PEX11A	8800	peroxisomal biogenesis factor 11 alpha	peroxisome membrane biogenesis	Biological process	-
CLIC4	25932	chloride intracellular channel 4	cytosol	Cellular component	10026142
ZNF580	51157	zinc finger protein 580	metal ion binding	Molecular function	-
MED8	112950	mediator complex subunit 8	protein ubiquitination	Biological process	-
PROS1	5627	protein S (alpha)	platelet alpha granule lumen	Cellular component	-
STAT5B	6777	signal transducer and activator of transcription 5B	fatty acid metabolic process	Biological process	-
PIK3C2B	5287	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta	phosphatidylinositol 3-kinase complex	Cellular component	-
IL3	3562	interleukin 3	positive regulation of DNA replication	Biological process	9722506
DDX25	29118	DEAD (Asp-Glu-Ala-Asp) box helicase 25	spermatid development	Biological process	-
KIAA1683	80726	KIAA1683	mitochondrion	Cellular component	-
GSTM2	2946	glutathione S-transferase mu 2 (muscle)	cytosol	Cellular component	-
NUMB	8650	numb homolog (Drosophila)	protein binding	Molecular function	17203073
TRPV2	51393	transient receptor potential cation channel, subfamily V, member 2	response to temperature stimulus	Biological process	10201375
RIMKLA	284716	ribosomal modification protein rimK-like family member A	ATP binding	Molecular function	-
HABP4	22927	hyaluronan binding protein 4	cytosol	Cellular component	-
ZCCHC17	51538	zinc finger, CCHC domain containing 17	zinc ion binding	Molecular function	-
OTX2	5015	orthodenticle homeobox 2	protein binding	Molecular function	20530484
CHIC1	53344	cysteine-rich hydrophobic domain 1	plasma membrane	Cellular component	-
STAB1	23166	stabilin 1	inflammatory response	Biological process	-
CDK12	51755	cyclin-dependent kinase 12	mRNA processing	Biological process	-
SPATA19	219938	spermatogenesis associated 19	spermatogenesis	Biological process	-
FOXA1	3169	forkhead box A1	positive regulation of neuron differentiation	Biological process	-
TUBAL3	79861	tubulin, alpha-like 3	metabolic process	Biological process	-
ZNF844	284391	zinc finger protein 844	metal ion binding	Molecular function	-
NFATC3	4775	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	positive regulation of transcription from RNA polymerase II promoter	Biological process	15173172
STIM2	57620	stromal interaction molecule 2	plasma membrane	Cellular component	18160041
CD274	29126	CD274 molecule	endomembrane system	Cellular component	-
UBE2E2	7325	ubiquitin-conjugating enzyme E2E 2	ubiquitin-protein transferase activity	Molecular function	20061386
FOXC1	2296	forkhead box C1	negative regulation of lymphangiogenesis	Biological process	-
SLC27A1	376497	solute carrier family 27 (fatty acid transporter), member 1	long-chain fatty acid transport	Biological process	-
RABAC1	10567	Rab acceptor 1 (prenylated)	membrane	Cellular component	19946888
Sep-12	124404	septin 12	cell cycle	Biological process	-
FZD10	11211	frizzled class receptor 10	protein binding	Molecular function	15930302
ELOVL2	54898	ELOVL fatty acid elongase 2	endoplasmic reticulum	Cellular component	20937905
ERGIC1	57222	endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1	endoplasmic reticulum-Golgi intermediate compartment	Cellular component	15308636
CTSC	1075	cathepsin C	response to organic substance	Biological process	-
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	T cell differentiation in thymus	Biological process	-
RECQL5	9400	RecQ protein-like 5	ATP binding	Molecular function	-
OR52E6	390078	olfactory receptor, family 52, subfamily E, member 6	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
NTRK2	4915	neurotrophic tyrosine kinase, receptor, type 2	oligodendrocyte differentiation	Biological process	-
TUBA1B	10376	tubulin, alpha 1b	cellular protein metabolic process	Biological process	-
CRHBP	1393	corticotropin releasing hormone binding protein	secondary lysosome	Cellular component	-
WDR1	9948	WD repeat domain 1	platelet degranulation	Biological process	-
ALS2CR12	130540	amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12	outer dense fiber	Cellular component	-
SRF	6722	serum response factor (c-fos serum response element-binding transcription factor)	positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation	Biological process	19783823
CACNB1	782	calcium channel, voltage-dependent, beta 1 subunit	sarcoplasmic reticulum	Cellular component	-
KIFC3	3801	kinesin family member C3	epithelial cell-cell adhesion	Biological process	19041755
UBA52	7311	ubiquitin A-52 residue ribosomal protein fusion product 1	stimulatory C-type lectin receptor signaling pathway	Biological process	-
LXN	56925	latexin	protein binding	Molecular function	25416956
CHRNA2	1135	cholinergic receptor, nicotinic, alpha 2 (neuronal)	acetylcholine receptor activity	Molecular function	8906617
RAC1	5879	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	negative regulation of receptor-mediated endocytosis	Biological process	9312003
TNF	7124	tumor necrosis factor	negative regulation of myoblast differentiation	Biological process	-
SLC32A1	140679	solute carrier family 32 (GABA vesicular transporter), member 1	integral component of membrane	Cellular component	-
INPP5K	51763	inositol polyphosphate-5-phosphatase K	trans-Golgi network	Cellular component	12556481
CATSPERB	79820	catsper channel auxiliary subunit beta	multicellular organismal development	Biological process	-
NFASC	23114	neurofascin	myelination	Biological process	-
SLC27A5	10998	solute carrier family 27 (fatty acid transporter), member 5	protein complex binding	Molecular function	-
SCN10A	6336	sodium channel, voltage gated, type X alpha subunit	plasma membrane	Cellular component	-
STAT5A	6776	signal transducer and activator of transcription 5A	succinate metabolic process	Biological process	-
NSMCE2	286053	non-SMC element 2, MMS21 homolog (S. cerevisiae)	Smc5-Smc6 complex	Cellular component	18086888
BCDIN3D	144233	BCDIN3 domain containing	RNA methylation	Biological process	23063121
IPO4	79711	importin 4	nuclear chromatin	Cellular component	14718166
UBA2	10054	ubiquitin-like modifier activating enzyme 2	positive regulation of catalytic activity	Biological process	10187858
ITPKA	3706	inositol-trisphosphate 3-kinase A	ATP binding	Molecular function	-
KCNMB1	3779	potassium channel subfamily M regulatory beta subunit 1	potassium ion transmembrane transport	Biological process	8612769
FBXW11	23291	F-box and WD repeat domain containing 11	protein dimerization activity	Molecular function	-
PHKA1	5255	phosphorylase kinase, alpha 1 (muscle)	protein phosphorylation	Biological process	8226841
LANCL2	55915	LanC lantibiotic synthetase component C-like 2 (bacterial)	phosphatidylinositol-5-phosphate binding	Molecular function	16979580
NKX1-1	54729	NK1 homeobox 1	regulation of generation of precursor metabolites and energy	Biological process	-
DAPP1	27071	dual adaptor of phosphotyrosine and 3-phosphoinositides	phosphatidylinositol-3,4,5-trisphosphate binding	Molecular function	11001876
DYNC1H1	1778	dynein, cytoplasmic 1, heavy chain 1	cytoplasmic dynein complex	Cellular component	8666668
INTS1	26173	integrator complex subunit 1	membrane	Cellular component	19946888
UBP1	7342	upstream binding protein 1 (LBP-1a)	sequence-specific DNA binding transcription factor activity	Molecular function	8114710
KCNJ11	3767	potassium channel, inwardly rectifying subfamily J, member 11	cytosol	Cellular component	-
C1GALT1	56913	core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1	cellular protein metabolic process	Biological process	-
PARK7	11315	parkinson protein 7	peptidase activity	Molecular function	20304780
NCF1	653361	neutrophil cytosolic factor 1	small GTPase mediated signal transduction	Biological process	-
TPMT	7172	thiopurine S-methyltransferase	xenobiotic metabolic process	Biological process	-
SORBS3	10174	sorbin and SH3 domain containing 3	actin filament organization	Biological process	-
PROK1	84432	prokineticin 1	extracellular region	Cellular component	-
GLCE	26035	glucuronic acid epimerase	heparosan-N-sulfate-glucuronate 5-epimerase activity	Molecular function	20118238
GIT1	28964	G protein-coupled receptor kinase interacting ArfGAP 1	cytosol	Cellular component	-
PRPS2	5634	phosphoribosyl pyrophosphate synthetase 2	organ regeneration	Biological process	-
TOX2	84969	TOX high mobility group box family member 2	chromatin remodeling	Biological process	-
RAET1G	353091	retinoic acid early transcript 1G	peptide antigen binding	Molecular function	-
MTOR	2475	mechanistic target of rapamycin (serine/threonine kinase)	phosphatidylinositol 3-kinase complex	Cellular component	15539461
PROK2	60675	prokineticin 2	positive regulation of smooth muscle contraction	Biological process	11259612
GRIN1	2902	glutamate receptor, ionotropic, N-methyl D-aspartate 1	synaptic vesicle	Cellular component	-
PRKD2	25865	protein kinase D2	plasma membrane	Cellular component	-
FOXG1	2290	forkhead box G1	inner ear morphogenesis	Biological process	-
OR13F1	138805	olfactory receptor, family 13, subfamily F, member 1	integral component of plasma membrane	Cellular component	-
ABCC6	368	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	transmembrane transport	Biological process	-
SLC41A3	54946	solute carrier family 41, member 3	protein binding	Molecular function	25416956
KCNC4	3749	potassium channel, voltage gated Shaw related subfamily C, member 4	neuromuscular junction	Cellular component	-
IFNA7	3444	interferon, alpha 7	blood coagulation	Biological process	-
NRXN3	9369	neurexin 3	adult behavior	Biological process	22209245
KDELR3	11015	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3	cellular protein metabolic process	Biological process	-
GPS1	2873	G protein pathway suppressor 1	protein binding	Molecular function	18850735
ATP13A4	84239	ATPase type 13A4	cation transport	Biological process	-
BMP1	649	bone morphogenetic protein 1	extracellular matrix organization	Biological process	-
IFNAR2	3455	interferon (alpha, beta and omega) receptor 2	response to virus	Biological process	7588638
TRPV4	59341	transient receptor potential cation channel, subfamily V, member 4	actin filament binding	Molecular function	-
PTF1A	256297	pancreas specific transcription factor, 1a	chromatin binding	Molecular function	-
DST	667	dystonin	endoplasmic reticulum membrane	Cellular component	-
RPL37AP8	644338	ribosomal protein L37a pseudogene 8	ribosome	Cellular component	-
GATA6	2627	GATA binding protein 6	cellular response to gonadotropin stimulus	Biological process	-
WDR1	9948	WD repeat domain 1	actin filament	Cellular component	-
ATP6V1E1	529	ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1	proton-transporting ATPase activity, rotational mechanism	Molecular function	-
HOXC10	3226	homeobox C10	proximal/distal pattern formation	Biological process	-
HABP4	22927	hyaluronan binding protein 4	regulation of transcription, DNA-templated	Biological process	-
TSC2	7249	tuberous sclerosis 2	protein kinase B signaling	Biological process	-
MPC1	51660	mitochondrial pyruvate carrier 1	pyruvate metabolic process	Biological process	-
BRK1	55845	BRICK1, SCAR/WAVE actin-nucleating complex subunit	actin cytoskeleton organization	Biological process	-
PTTG3P	26255	pituitary tumor-transforming 3, pseudogene	cytoplasm	Cellular component	-
CYP11B2	1585	cytochrome P450, family 11, subfamily B, polypeptide 2	mitochondrial inner membrane	Cellular component	-
IYD	389434	iodotyrosine deiodinase	integral component of membrane	Cellular component	-
RAVER2	55225	ribonucleoprotein, PTB-binding 2	poly(A) RNA binding	Molecular function	22658674
DDR2	4921	discoidin domain receptor tyrosine kinase 2	integral component of plasma membrane	Cellular component	-
BCAT1	586	branched chain amino-acid transaminase 1, cytosolic	L-valine transaminase activity	Molecular function	-
CYFIP2	26999	cytoplasmic FMR1 interacting protein 2	apoptotic process	Biological process	10449408
CHD5	26038	chromodomain helicase DNA binding protein 5	H3K27me3 modified histone binding	Molecular function	23948251
GIPC1	10755	GIPC PDZ domain containing family, member 1	extracellular exosome	Cellular component	19056867
ADRB1	153	adrenoceptor beta 1	negative regulation of urine volume	Biological process	-
VAMP8	8673	vesicle-associated membrane protein 8	syntaxin binding	Molecular function	-
SHOX2	6474	short stature homeobox 2	cartilage development involved in endochondral bone morphogenesis	Biological process	-
BAP1	8314	BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)	nucleoplasm	Cellular component	-
VLDLR	7436	very low density lipoprotein receptor	very-low-density lipoprotein particle clearance	Biological process	8083232
PLA2G4F	255189	phospholipase A2, group IVF	phosphatidylserine acyl-chain remodeling	Biological process	-
SPOPL	339745	speckle-type POZ protein-like	protein binding	Molecular function	25416956
B4GALT7	11285	xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7	cellular protein modification process	Biological process	10473568
CBFA2T3	863	core-binding factor, runt domain, alpha subunit 2; translocated to, 3	sequence-specific DNA binding transcription factor activity	Molecular function	-
S100B	6285	S100 calcium binding protein B	memory	Biological process	-
ALKBH6	84964	alkB, alkylation repair homolog 6 (E. coli)	metal ion binding	Molecular function	-
SMAP2	64744	small ArfGAP2	protein binding	Molecular function	25416956
KEL	3792	Kell blood group, metallo-endopeptidase	metal ion binding	Molecular function	-
PHACTR4	65979	phosphatase and actin regulator 4	neural crest cell migration	Biological process	-
SORT1	6272	sortilin 1	lysosomal membrane	Cellular component	-
TIMM21	29090	translocase of inner mitochondrial membrane 21 homolog (yeast)	protein binding	Molecular function	23260140
ATP5B	506	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide	mitochondrial nucleoid	Cellular component	18063578
IFT140	9742	intraflagellar transport 140	skeletal system morphogenesis	Biological process	22503633
PIK3R4	30849	phosphoinositide-3-kinase, regulatory subunit 4	protein targeting to vacuole	Biological process	-
MMADHC	27249	methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria	vitamin metabolic process	Biological process	-
OSM	5008	oncostatin M	negative regulation of meiotic nuclear division	Biological process	-
LLGL1	3996	lethal giant larvae homolog 1 (Drosophila)	protein binding	Molecular function	7542763
GRIN2B	2904	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	regulation of protein kinase A signaling	Biological process	-
IKBKE	9641	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	I-kappaB phosphorylation	Biological process	-
PAK3	5063	p21 protein (Cdc42/Rac)-activated kinase 3	Rac GTPase binding	Molecular function	-
PEA15	8682	phosphoprotein enriched in astrocytes 15	apoptotic process	Biological process	-
EVL	51466	Enah/Vasp-like	positive regulation of stress fiber assembly	Biological process	23153535
RPL23	9349	ribosomal protein L23	translation	Biological process	-
PRTN3	5657	proteinase 3	collagen catabolic process	Biological process	-
CELA3A	10136	chymotrypsin-like elastase family, member 3A	serine-type endopeptidase activity	Molecular function	-
TSFM	10102	Ts translation elongation factor, mitochondrial	mitochondrial translation	Biological process	-
CABP4	57010	calcium binding protein 4	retinal bipolar neuron differentiation	Biological process	-
CHD5	26038	chromodomain helicase DNA binding protein 5	ATP binding	Molecular function	-
NLRP5	126206	NLR family, pyrin domain containing 5	ATP binding	Molecular function	-
HIST2H4A	8370	histone cluster 2, H4a	histone H4-K20 demethylation	Biological process	-
COL16A1	1307	collagen, type XVI, alpha 1	cellular response to amino acid stimulus	Biological process	-
MRPL48	51642	mitochondrial ribosomal protein L48	protein binding	Molecular function	20601428
ADAM12	8038	ADAM metallopeptidase domain 12	myoblast fusion	Biological process	7566181
CREB1	1385	cAMP responsive element binding protein 1	lung saccule development	Biological process	-
ZFP36L2	678	ZFP36 ring finger protein-like 2	metal ion binding	Molecular function	-
XPOT	11260	exportin, tRNA	Ran GTPase binding	Molecular function	-
GAPDH	2597	glyceraldehyde-3-phosphate dehydrogenase	microtubule cytoskeleton	Cellular component	-
GPRC6A	222545	G protein-coupled receptor, class C, group 6, member A	plasma membrane	Cellular component	-
TPD52L3	89882	tumor protein D52-like 3	protein binding	Molecular function	25416956
WISP2	8839	WNT1 inducible signaling pathway protein 2	signal transduction	Biological process	9843955
NOTCH1	4851	notch 1	regulation of epithelial cell proliferation involved in prostate gland development	Biological process	-
MEF2C	4208	myocyte enhancer factor 2C	apoptotic process	Biological process	-
NAA15	80155	N(alpha)-acetyltransferase 15, NatA auxiliary subunit	NatA complex	Cellular component	15496142
CAV1	857	caveolin 1, caveolae protein, 22kDa	endoplasmic reticulum	Cellular component	11294831
FLT3	2322	fms-related tyrosine kinase 3	hemopoiesis	Biological process	7507245
GNPAT	8443	glyceronephosphate O-acyltransferase	response to fatty acid	Biological process	-
STX2	2054	syntaxin 2	extracellular exosome	Cellular component	23376485
HSPA5	3309	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	COP9 signalosome	Cellular component	18850735
MYH9	4627	myosin, heavy chain 9, non-muscle	ATP binding	Molecular function	15065866
SCAI	286205	suppressor of cancer cell invasion	transcription corepressor activity	Molecular function	19350017
SMARCA1	6594	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1	brain development	Biological process	14609955
L1CAM	3897	L1 cell adhesion molecule	homotypic cell-cell adhesion	Biological process	-
RAB43	339122	RAB43, member RAS oncogene family	endosome	Cellular component	-
EIF5A2	56648	eukaryotic translation initiation factor 5A2	nuclear pore	Cellular component	-
XPC	7508	xeroderma pigmentosum, complementation group C	mismatch repair	Biological process	-
VWF	7450	von Willebrand factor	Weibel-Palade body	Cellular component	3082891
PSMA6	5687	proteasome (prosome, macropain) subunit, alpha type, 6	nucleus	Cellular component	-
TRAK1	22906	trafficking protein, kinesin binding 1	GABA receptor binding	Molecular function	-
LAMA1	284217	laminin, alpha 1	retinal blood vessel morphogenesis	Biological process	-
FKBP14	55033	FK506 binding protein 14, 22 kDa	protein peptidyl-prolyl isomerization	Biological process	-
GALT	2592	galactose-1-phosphate uridylyltransferase	galactose metabolic process	Biological process	1427861
PKMYT1	9088	protein kinase, membrane associated tyrosine/threonine 1	regulation of mitotic nuclear division	Biological process	9001210
DSCR3	10311	Down syndrome critical region 3	intracellular protein transport	Biological process	-
ERVV-2	100271846	endogenous retrovirus group V, member 2	integral component of membrane	Cellular component	-
PTBP1	5725	polypyrimidine tract binding protein 1	nucleoplasm	Cellular component	-
ADGRG6	57211	adhesion G protein-coupled receptor G6	G-protein coupled receptor signaling pathway	Biological process	-
FN1	2335	fibronectin 1	regulation of cell shape	Biological process	-
HAT1	8520	histone acetyltransferase 1	chromatin organization	Biological process	-
ACTB	60	actin, beta	extracellular space	Cellular component	16502470
ARL6	84100	ADP-ribosylation factor-like 6	axonemal microtubule	Cellular component	-
LY6H	4062	lymphocyte antigen 6 complex, locus H	plasma membrane	Cellular component	-
MXD1	4084	MAX dimerization protein 1	negative regulation of transcription from RNA polymerase II promoter	Biological process	10723141
PUM1	9698	pumilio RNA-binding family member 1	regulation of translation	Biological process	-
VIPR2	7434	vasoactive intestinal peptide receptor 2	activation of adenylate cyclase activity	Biological process	-
SLC7A5	8140	solute carrier family 7 (amino acid transporter light chain, L system), member 5	transport	Biological process	9751058
PCDH7	5099	protocadherin 7	integral component of plasma membrane	Cellular component	9615233
ARHGAP42	143872	Rho GTPase activating protein 42	signal transduction	Biological process	-
ATP8A1	10396	ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1	metabolic process	Biological process	-
CBY1	25776	chibby homolog 1 (Drosophila)	nucleus	Cellular component	12712206
BRIP1	83990	BRCA1 interacting protein C-terminal helicase 1	metal ion binding	Molecular function	-
SIPA1L3	23094	signal-induced proliferation-associated 1 like 3	GTPase activator activity	Molecular function	-
DTNA	1837	dystrobrevin, alpha	signal transduction	Biological process	10767327
FLOT1	10211	flotillin 1	positive regulation of cell-cell adhesion mediated by cadherin	Biological process	24046456
SLC13A5	284111	solute carrier family 13 (sodium-dependent citrate transporter), member 5	tricarboxylic acid transmembrane transport	Biological process	-
IL23A	51561	interleukin 23, alpha subunit p19	positive regulation of interleukin-12 production	Biological process	20027291
HUS1	3364	HUS1 checkpoint homolog (S. pombe)	DNA damage checkpoint	Biological process	21659603
PLOD3	8985	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3	rough endoplasmic reticulum membrane	Cellular component	-
SLC4A1	6521	solute carrier family 4 (anion exchanger), member 1 (Diego blood group)	integral component of membrane	Cellular component	1527044
LIMD1	8994	LIM domains containing 1	negative regulation of canonical Wnt signaling pathway	Biological process	-
CORO7	79585	coronin 7	protein transport	Biological process	-
TRIM15	89870	tripartite motif containing 15	negative regulation of intracellular transport of viral material	Biological process	18248090
BATF	10538	basic leucine zipper transcription factor, ATF-like	T-helper 17 cell differentiation	Biological process	-
SLC25A13	10165	solute carrier family 25 (aspartate/glutamate carrier), member 13	transporter activity	Molecular function	10642534
SRC	6714	SRC proto-oncogene, non-receptor tyrosine kinase	uterus development	Biological process	-
SLC28A3	64078	solute carrier family 28 (concentrative nucleoside transporter), member 3	purine nucleoside transmembrane transport	Biological process	-
ERVK-10	100616101	endogenous retrovirus group K, member 10	DNA binding	Molecular function	-
CISD1	55847	CDGSH iron sulfur domain 1	regulation of cellular respiration	Biological process	-
SOAT2	8435	sterol O-acyltransferase 2	transferase activity, transferring acyl groups	Molecular function	9756920
KCNF1	3754	potassium channel, voltage gated modifier subfamily F, member 1	voltage-gated potassium channel complex	Cellular component	-
PDCD10	11235	programmed cell death 10	establishment of Golgi localization	Biological process	20332113
ZNF106	64397	zinc finger protein 106	SH3 domain binding	Molecular function	-
ASZ1	136991	ankyrin repeat, SAM and basic leucine zipper domain containing 1	piRNA metabolic process	Biological process	-
HIST1H3J	8356	histone cluster 1, H3j	small GTPase mediated signal transduction	Biological process	-
FIS1	51024	fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)	protein complex	Cellular component	17408615
EIF6	3692	eukaryotic translation initiation factor 6	nucleoplasm	Cellular component	-
LCT	3938	lactase	plasma membrane	Cellular component	-
MPC1L	347411	mitochondrial pyruvate carrier 1-like	mitochondrial pyruvate transport	Biological process	-
TAF5	6877	TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa	transcription factor TFTC complex	Cellular component	10373431
RBM15	64783	RNA binding motif protein 15	nuclear membrane	Cellular component	-
TREX1	11277	three prime repair exonuclease 1	DNA catabolic process, exonucleolytic	Biological process	-
TSHZ3	57616	teashirt zinc finger homeobox 3	metanephros development	Biological process	-
SORT1	6272	sortilin 1	neuropeptide signaling pathway	Biological process	9756851
ORC2	4999	origin recognition complex, subunit 2	negative regulation of transcription from RNA polymerase II promoter	Biological process	8808289
DHRS4L2	317749	dehydrogenase/reductase (SDR family) member 4 like 2	oxidation-reduction process	Biological process	-
ASIC2	40	acid sensing (proton gated) ion channel 2	plasma membrane	Cellular component	-
PLOD1	5351	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1	response to hypoxia	Biological process	15174142
MTG2	26164	mitochondrial ribosome-associated GTPase 2	ribosome biogenesis	Biological process	-
CIT	11113	citron rho-interacting serine/threonine kinase	ruffle	Cellular component	-
GOT2	2806	glutamic-oxaloacetic transaminase 2, mitochondrial	extracellular exosome	Cellular component	20458337
HS3ST2	9956	heparan sulfate (glucosamine) 3-O-sulfotransferase 2	small molecule metabolic process	Biological process	-
AGR3	155465	anterior gradient 3	cellular_component	Cellular component	-
ANOS1	3730	anosmin 1	protein binding	Molecular function	19696444
PDGFB	5155	platelet-derived growth factor beta polypeptide	endoplasmic reticulum lumen	Cellular component	-
PARN	5073	poly(A)-specific ribonuclease	metal ion binding	Molecular function	-
PTPN13	5783	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)	neuron projection	Cellular component	-
AURKA	6790	aurora kinase A	nucleus	Cellular component	20531406
FKBP7	51661	FK506 binding protein 7	protein peptidyl-prolyl isomerization	Biological process	-
FCHO2	115548	FCH domain only 2	protein localization to plasma membrane	Biological process	-
CD276	80381	CD276 molecule	protein binding	Molecular function	18650384
HDAC1	3065	histone deacetylase 1	embryonic digit morphogenesis	Biological process	-
NDUFS1	4719	NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)	mitochondrial respiratory chain complex I	Cellular component	9878551
S100A8	6279	S100 calcium binding protein A8	defense response to bacterium	Biological process	22489132
PAX2	5076	paired box 2	protein complex	Cellular component	-
AP2B1	163	adaptor-related protein complex 2, beta 1 subunit	intracellular protein transport	Biological process	-
SCGN	10590	secretagogin, EF-hand calcium binding protein	cytoplasm	Cellular component	10811645
BEST1	7439	bestrophin 1	visual perception	Biological process	9662395
SRA1	10011	steroid receptor RNA activator 1	ligand-dependent nuclear receptor transcription coactivator activity	Molecular function	-
IL27RA	9466	interleukin 27 receptor, alpha	interleukin-27 receptor activity	Molecular function	-
HIST1H3H	8357	histone cluster 1, H3h	regulation of gene silencing	Biological process	16267050
GSTM1	2944	glutathione S-transferase mu 1	xenobiotic catabolic process	Biological process	8373352
HSPA1A	3303	heat shock 70kDa protein 1A	ATP metabolic process	Biological process	23921388
EPB41L5	57669	erythrocyte membrane protein band 4.1 like 5	axial mesoderm morphogenesis	Biological process	-
GJB4	127534	gap junction protein, beta 4, 30.3kDa	integral component of membrane	Cellular component	-
HOXD10	3236	homeobox D10	peripheral nervous system neuron development	Biological process	-
TWIST2	117581	twist family bHLH transcription factor 2	negative regulation of DNA binding	Biological process	-
RSG1	79363	REM2 and RAB-like small GTPase 1	protein binding	Molecular function	25416956
SOCS1	8651	suppressor of cytokine signaling 1	JAK-STAT cascade involved in growth hormone signaling pathway	Biological process	-
GLIS1	148979	GLIS family zinc finger 1	RNA polymerase II regulatory region sequence-specific DNA binding	Molecular function	-
LECT2	3950	leukocyte cell-derived chemotaxin 2	cytoplasm	Cellular component	-
ACVR1	90	activin A receptor, type I	signal transduction by protein phosphorylation	Biological process	-
ABAT	18	4-aminobutyrate aminotransferase	response to ethanol	Biological process	-
NEU1	4758	sialidase 1 (lysosomal sialidase)	cell junction	Cellular component	-
FBXL15	79176	F-box and leucine-rich repeat protein 15	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological process	21572392
GNB2L1	10399	guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1	small ribosomal subunit	Cellular component	-
SPHK1	8877	sphingosine kinase 1	signal transduction	Biological process	10751414
PPEF1	5475	protein phosphatase, EF-hand calcium binding domain 1	phototransduction, visible light	Biological process	-
EMP2	2013	epithelial membrane protein 2	protein kinase binding	Molecular function	21637765
ZNF112	7771	zinc finger protein 112	nucleus	Cellular component	-
PLIN2	123	perilipin 2	nucleus	Cellular component	-
NAT8	9027	N-acetyltransferase 8 (GCN5-related, putative)	response to drug	Biological process	9852678
RPL10	6134	ribosomal protein L10	cytosolic large ribosomal subunit	Cellular component	12962325
ZNF527	84503	zinc finger protein 527	metal ion binding	Molecular function	-
CTNNA2	1496	catenin (cadherin-associated protein), alpha 2	positive regulation of muscle cell differentiation	Biological process	-
CTTN	2017	cortactin	actin filament polymerization	Biological process	-
CD69	969	CD69 molecule	carbohydrate binding	Molecular function	-
TCF20	6942	transcription factor 20 (AR1)	poly(A) RNA binding	Molecular function	22658674
SHH	6469	sonic hedgehog	odontogenesis of dentin-containing tooth	Biological process	-
ARRB2	409	arrestin, beta 2	protein ubiquitination	Biological process	15878855
EYA2	2139	EYA transcriptional coactivator and phosphatase 2	centrosome	Cellular component	-
WASF2	10163	WAS protein family, member 2	viral process	Biological process	-
ARL6IP5	10550	ADP-ribosylation factor-like 6 interacting protein 5	integral component of membrane	Cellular component	-
NAPA	8775	N-ethylmaleimide-sensitive factor attachment protein, alpha	synaptic transmission, glutamatergic	Biological process	-
DNAH6	1768	dynein, axonemal, heavy chain 6	microtubule-based movement	Biological process	-
MYH2	4620	myosin, heavy chain 2, skeletal muscle, adult	Fc-gamma receptor signaling pathway involved in phagocytosis	Biological process	-
CAMK2B	816	calcium/calmodulin-dependent protein kinase II beta	calcium ion transport	Biological process	-
ATP6V0D1	9114	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1	hydrogen-exporting ATPase activity, phosphorylative mechanism	Molecular function	-
COG5	10466	component of oligomeric golgi complex 5	Golgi membrane	Cellular component	-
CHRNB3	1142	cholinergic receptor, nicotinic, beta 3 (neuronal)	synaptic transmission, cholinergic	Biological process	7690916
RBM5	10181	RNA binding motif protein 5	RNA splicing	Biological process	-
CARKD	55739	carbohydrate kinase domain containing	biological_process	Biological process	-
MYOD1	4654	myogenic differentiation 1	myotube cell development	Biological process	10672515
TRAFD1	10906	TRAF-type zinc finger domain containing 1	metal ion binding	Molecular function	-
GNRH1	2796	gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)	negative regulation of cell proliferation	Biological process	10832105
TSHZ3	57616	teashirt zinc finger homeobox 3	lung development	Biological process	-
ARNT2	9915	aryl-hydrocarbon receptor nuclear translocator 2	positive regulation of transcription, DNA-templated	Biological process	-
IRF2	3660	interferon regulatory factor 2	DNA binding	Molecular function	9540062
OGFRL1	79627	opioid growth factor receptor-like 1	membrane	Cellular component	-
TMPRSS2	7113	transmembrane protease, serine 2	integral component of plasma membrane	Cellular component	9325052
UBR3	130507	ubiquitin protein ligase E3 component n-recognin 3 (putative)	ligase activity	Molecular function	-
DGKD	8527	diacylglycerol kinase, delta 130kDa	epidermal growth factor receptor signaling pathway	Biological process	12200442
NF1	4763	neurofibromin 1	MAPK cascade	Biological process	-
ERI1	90459	exoribonuclease 1	gene silencing by RNA	Biological process	-
MAD2L1BP	9587	MAD2L1 binding protein	intracellular membrane-bounded organelle	Cellular component	-
ANKRD1	27063	ankyrin repeat domain 1 (cardiac muscle)	cellular response to hypoxia	Biological process	-
CBS	875	cystathionine-beta-synthase	hydrogen sulfide biosynthetic process	Biological process	-
PDE12	201626	phosphodiesterase 12	RNA phosphodiester bond hydrolysis, exonucleolytic	Biological process	-
IRAK1	3654	interleukin-1 receptor-associated kinase 1	NF-kappaB-inducing kinase activity	Molecular function	8599092
MCM2	4171	minichromosome maintenance complex component 2	chromatin	Cellular component	16899510
ATP7A	538	ATPase, Cu++ transporting, alpha polypeptide	response to iron(III) ion	Biological process	-
MT1X	4501	metallothionein 1X	detoxification of copper ion	Biological process	-
TBX1	6899	T-box 1	muscle organ morphogenesis	Biological process	-
WRNIP1	56897	Werner helicase interacting protein 1	DNA replication	Biological process	-
PRKCD	5580	protein kinase C, delta	negative regulation of peptidyl-tyrosine phosphorylation	Biological process	14583092
ACTC1	70	actin, alpha, cardiac muscle 1	ATPase activity	Molecular function	16611632
SUPT20H	55578	suppressor of Ty 20 homolog (S. cerevisiae)	transcription cofactor activity	Molecular function	-
EWSR1	2130	EWS RNA-binding protein 1	nucleus	Cellular component	-
ZDHHC8	29801	zinc finger, DHHC-type containing 8	mitochondrion	Cellular component	-
SMARCA4	6597	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	nucleolus	Cellular component	-
UCHL1	7345	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)	axon target recognition	Biological process	-
SMC3	9126	structural maintenance of chromosomes 3	cellular protein metabolic process	Biological process	-
PATL1	219988	protein associated with topoisomerase II homolog 1 (yeast)	nuclear speck	Cellular component	-
MOB1B	92597	MOB kinase activator 1B	protein autophosphorylation	Biological process	15197186
FKBP1B	2281	FK506 binding protein 1B, 12.6 kDa	cell communication by electrical coupling involved in cardiac conduction	Biological process	22087651
HOMER2	9455	homer scaffolding protein 2	nucleoplasm	Cellular component	-
GRM1	2911	glutamate receptor, metabotropic 1	sensory perception of pain	Biological process	-
F5	2153	coagulation factor V (proaccelerin, labile factor)	proteolysis	Biological process	-
HIF1A	3091	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	sequence-specific DNA binding	Molecular function	7539918
RIPK3	11035	receptor-interacting serine-threonine kinase 3	toll-like receptor 4 signaling pathway	Biological process	-
GRIA2	2891	glutamate receptor, ionotropic, AMPA 2	endocytic vesicle membrane	Cellular component	-
IMPA1	3612	inositol(myo)-1(or 4)-monophosphatase 1	lithium ion binding	Molecular function	9462881
EGFR	1956	epidermal growth factor receptor	endosome membrane	Cellular component	22719997
EXOSC8	11340	exosome component 8	cytoplasm	Cellular component	17545563
CTPS1	1503	CTP synthase 1	ATP binding	Molecular function	-
GFRA3	2676	GDNF family receptor alpha 3	signal transduction	Biological process	9490034
BAX	581	BCL2-associated X protein	negative regulation of apoptotic signaling pathway	Biological process	-
MYO10	4651	myosin X	cell cortex	Cellular component	-
UNC119	9094	unc-119 homolog (C. elegans)	lipoprotein transport	Biological process	21642972
PPP2R5A	5525	protein phosphatase 2, regulatory subunit B', alpha	nucleus	Cellular component	-
ATF6	22926	activating transcription factor 6	transcription, DNA-templated	Biological process	-
ZNF844	284391	zinc finger protein 844	nucleus	Cellular component	-
G6PD	2539	glucose-6-phosphate dehydrogenase	cytosol	Cellular component	-
TMF1	7110	TATA element modulatory factor 1	Golgi membrane	Cellular component	-
UNC5D	137970	unc-5 homolog D (C. elegans)	signal transduction	Biological process	-
CCL21	6366	chemokine (C-C motif) ligand 21	positive regulation of myeloid dendritic cell chemotaxis	Biological process	14592837
TDP2	51567	tyrosyl-DNA phosphodiesterase 2	cytoplasm	Cellular component	22908287
NR2C1	7181	nuclear receptor subfamily 2, group C, member 1	positive regulation of retinoic acid receptor signaling pathway	Biological process	-
ITGAM	3684	integrin, alpha M (complement component 3 receptor 3 subunit)	opsonin binding	Molecular function	-
PRAMEF5	343068	PRAME family member 5	negative regulation of cell differentiation	Biological process	-
YWHAB	7529	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta	melanosome	Cellular component	-
CALCA	796	calcitonin-related polypeptide alpha	endothelial cell proliferation	Biological process	17267696
RPL24	6152	ribosomal protein L24	cytosol	Cellular component	-
THSD1	55901	thrombospondin, type I, domain containing 1	cytoplasm	Cellular component	-
MFSD10	10227	major facilitator superfamily domain containing 10	apoptotic process	Biological process	-
TMTC4	84899	transmembrane and tetratricopeptide repeat containing 4	integral component of membrane	Cellular component	-
BTBD10	84280	BTB (POZ) domain containing 10	nucleoplasm	Cellular component	-
GBP4	115361	guanylate binding protein 4	cytoplasm	Cellular component	-
EFNA2	1943	ephrin-A2	extracellular region	Cellular component	-
YOD1	55432	YOD1 deubiquitinase	protein K33-linked deubiquitination	Biological process	23827681
HNMT	3176	histamine N-methyltransferase	methylation	Biological process	-
WNT10A	80326	wingless-type MMTV integration site family, member 10A	epidermis morphogenesis	Biological process	20163410
OR2A25	392138	olfactory receptor, family 2, subfamily A, member 25	G-protein coupled receptor activity	Molecular function	-
CAMKV	79012	CaM kinase-like vesicle-associated	protein kinase activity	Molecular function	-
LRRCC1	85444	leucine rich repeat and coiled-coil centrosomal protein 1	cell division	Biological process	-
BACE1	23621	beta-site APP-cleaving enzyme 1	enzyme binding	Molecular function	12586838
CEP55	55165	centrosomal protein 55kDa	establishment of protein localization	Biological process	23045692
TELO2	9894	telomere maintenance 2	TORC2 complex	Cellular component	23263282
LAMTOR2	28956	late endosomal/lysosomal adaptor, MAPK and MTOR activator 2	Ragulator complex	Cellular component	20381137
VAMP7	6845	vesicle-associated membrane protein 7	neutrophil degranulation	Biological process	14993220
ENPP1	5167	ectonucleotide pyrophosphatase/phosphodiesterase 1	small molecule metabolic process	Biological process	-
VPS4B	9525	vacuolar protein sorting 4 homolog B (S. cerevisiae)	positive regulation of viral release from host cell	Biological process	14505570
NUMB	8650	numb homolog (Drosophila)	plasma membrane	Cellular component	-
QKI	9444	QKI, KH domain containing, RNA binding	RNA splicing	Biological process	-
SS18	6760	synovial sarcoma translocation, chromosome 18	protein binding	Molecular function	15919756
GLRX3	10539	glutaredoxin 3	poly(A) RNA binding	Molecular function	22658674
EED	8726	embryonic ectoderm development	negative regulation of transcription, DNA-templated	Biological process	9584199
CHRM1	1128	cholinergic receptor, muscarinic 1	positive regulation of ion transport	Biological process	14657398
CLCN3	1182	chloride channel, voltage-sensitive 3	synaptic vesicle	Cellular component	11182090
PARK7	11315	parkinson protein 7	tyrosine 3-monooxygenase activator activity	Molecular function	19703902
MFAP2	4237	microfibrillar-associated protein 2	fibronectin binding	Molecular function	-
SP100	6672	SP100 nuclear antigen	negative regulation of viral transcription	Biological process	16873258
BBS4	585	Bardet-Biedl syndrome 4	protein localization to centrosome	Biological process	15107855
OR1J4	26219	olfactory receptor, family 1, subfamily J, member 4	detection of chemical stimulus involved in sensory perception	Biological process	-
TRAF6	7189	TNF receptor-associated factor 6, E3 ubiquitin protein ligase	cytosol	Cellular component	-
SKI	6497	SKI proto-oncogene	negative regulation of histone deacetylation	Biological process	-
PGM1	5236	phosphoglucomutase 1	gluconeogenesis	Biological process	8257433
ZFAND6	54469	zinc finger, AN1-type domain 6	negative regulation of apoptotic process	Biological process	21810480
TRPM6	140803	transient receptor potential cation channel, subfamily M, member 6	response to toxic substance	Biological process	17575980
SMO	6608	smoothened, frizzled class receptor	positive regulation of neuroblast proliferation	Biological process	-
DLG5	9231	discs, large homolog 5 (Drosophila)	signal transduction	Biological process	9738934
HFE	3077	hemochromatosis	plasma membrane	Cellular component	10638746
SOD2	6648	superoxide dismutase 2, mitochondrial	mitochondrial nucleoid	Cellular component	-
CA6	765	carbonic anhydrase VI	carbonate dehydratase activity	Molecular function	-
HIST2H3C	126961	histone cluster 2, H3c	DNA methylation on cytosine	Biological process	-
SLC26A7	115111	solute carrier family 26 (anion exchanger), member 7	sulfate transmembrane transporter activity	Molecular function	1183472
MKNK1	8569	MAP kinase interacting serine/threonine kinase 1	intracellular signal transduction	Biological process	9155018
ACY3	91703	aminoacylase 3	small molecule metabolic process	Biological process	-
ATXN1	6310	ataxin 1	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
MUC21	394263	mucin 21, cell surface associated	plasma membrane	Cellular component	-
STX8	9482	syntaxin 8	regulation of protein localization to plasma membrane	Biological process	18570918
ZNF229	7772	zinc finger protein 229	DNA binding	Molecular function	-
EGF	1950	epidermal growth factor	epidermal growth factor receptor signaling pathway	Biological process	-
PML	5371	promyelocytic leukemia	nucleolus	Cellular component	15195100
MMGT1	93380	membrane magnesium transporter 1	integral component of membrane	Cellular component	22119785
PPP1R2P9	80316	protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9	regulation of phosphoprotein phosphatase activity	Biological process	-
DERA	51071	deoxyribose-phosphate aldolase (putative)	cytoplasm	Cellular component	-
MYH1	4619	myosin, heavy chain 1, skeletal muscle, adult	A band	Cellular component	-
MAPKAPK2	9261	mitogen-activated protein kinase-activated protein kinase 2	toll-like receptor TLR6:TLR2 signaling pathway	Biological process	-
UMODL1	89766	uromodulin-like 1	extracellular space	Cellular component	-
SOX10	6663	SRY (sex determining region Y)-box 10	positive regulation of neuroblast proliferation	Biological process	-
AKAP7	9465	A kinase (PRKA) anchor protein 7	cytosol	Cellular component	10613906
MAN2A2	4122	mannosidase, alpha, class 2A, member 2	mannose metabolic process	Biological process	-
KIF4A	24137	kinesin family member 4A	cytosol	Cellular component	-
IFNA5	3442	interferon, alpha 5	cytokine-mediated signaling pathway	Biological process	-
BOD1L1	259282	biorientation of chromosomes in cell division 1-like 1	DNA binding	Molecular function	-
PDE6H	5149	phosphodiesterase 6H, cGMP-specific, cone, gamma	activation of MAPK activity	Biological process	-
NRXN2	9379	neurexin 2	vocal learning	Biological process	21424692
LOC255308	255308	eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa pseudogene	GTPase activity	Molecular function	-
DDB1	1642	damage-specific DNA binding protein 1, 127kDa	nucleotide-excision repair	Biological process	-
WTIP	126374	Wilms tumor 1 interacting protein	nucleus	Cellular component	-
IDS	3423	iduronate 2-sulfatase	carbohydrate metabolic process	Biological process	-
ARHGEF7	8874	Rho guanine nucleotide exchange factor (GEF) 7	neuron projection	Cellular component	21048939
CLASP1	23332	cytoplasmic linker associated protein 1	G2/M transition of mitotic cell cycle	Biological process	-
MGST2	4258	microsomal glutathione S-transferase 2	response to organonitrogen compound	Biological process	-
MAPKAPK2	9261	mitogen-activated protein kinase-activated protein kinase 2	vascular endothelial growth factor receptor signaling pathway	Biological process	-
SMARCD2	6603	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2	protein binding	Molecular function	20148946
TLR10	81793	toll-like receptor 10	regulation of cytokine secretion	Biological process	-
CLTA	1211	clathrin, light chain A	intracellular protein transport	Biological process	-
MYSM1	114803	Myb-like, SWIRM and MPN domains 1	monoubiquitinated histone H2A deubiquitination	Biological process	17707232
PTTG1	9232	pituitary tumor-transforming 1	regulation of transcription, DNA-templated	Biological process	9811450
RMDN2	151393	regulator of microtubule dynamics 2	cytoplasm	Cellular component	-
ZNF391	346157	zinc finger protein 391	DNA binding	Molecular function	-
BBS2	583	Bardet-Biedl syndrome 2	striatum development	Biological process	-
MYH10	4628	myosin, heavy chain 10, non-muscle	cell proliferation	Biological process	-
MEF2A	4205	myocyte enhancer factor 2A	toll-like receptor 10 signaling pathway	Biological process	-
CPQ	10404	carboxypeptidase Q	proteolysis	Biological process	10206990
HIF1AN	55662	hypoxia inducible factor 1, alpha subunit inhibitor	cytosol	Cellular component	-
ADI1	55256	acireductone dioxygenase 1	oxidation-reduction process	Biological process	-
BRCA1	672	breast cancer 1, early onset	protein sumoylation	Biological process	-
SAA4	6291	serum amyloid A4, constitutive	extracellular exosome	Cellular component	23533145
ITGB1BP1	9270	integrin beta 1 binding protein 1	negative regulation of protein kinase activity	Biological process	20616313
C17orf62	79415	chromosome 17 open reading frame 62	protein binding	Molecular function	20195357
CLASP1	23332	cytoplasmic linker associated protein 1	microtubule plus-end binding	Molecular function	12837247
TUBB8	347688	tubulin, beta 8 class VIII	biological_process	Biological process	-
GNB2	2783	guanine nucleotide binding protein (G protein), beta polypeptide 2	GTPase activity	Molecular function	2902634
OR2T34	127068	olfactory receptor, family 2, subfamily T, member 34	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
PRCP	5547	prolylcarboxypeptidase (angiotensinase C)	blood coagulation, intrinsic pathway	Biological process	-
CXCR6	10663	chemokine (C-X-C motif) receptor 6	C-X-C chemokine receptor activity	Molecular function	-
PSMB2	5690	proteasome (prosome, macropain) subunit, beta type, 2	negative regulation of apoptotic process	Biological process	-
ABCB6	10058	ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)	brain development	Biological process	22100072
INTS9	55756	integrator complex subunit 9	protein binding	Molecular function	16239144
SYNGR3	9143	synaptogyrin 3	synaptic vesicle	Cellular component	-
IRX3	79191	iroquois homeobox 3	positive regulation of neuron differentiation	Biological process	-
CYB561	1534	cytochrome b561	electron transport chain	Biological process	7559396
PHF12	57649	PHD finger protein 12	Sin3 complex	Cellular component	22048773
PPIP5K1	9677	diphosphoinositol pentakisphosphate kinase 1	nucleoplasm	Cellular component	-
APTX	54840	aprataxin	double-strand break repair	Biological process	17519253
VAC14	55697	Vac14 homolog (S. cerevisiae)	endosome membrane	Cellular component	17556371
C3orf62	375341	chromosome 3 open reading frame 62	protein binding	Molecular function	25416956
MAP1LC3B	81631	microtubule-associated protein 1 light chain 3 beta	extrinsic component of membrane	Cellular component	-
PELI3	246330	pellino E3 ubiquitin protein ligase family member 3	negative regulation of type I interferon production	Biological process	-
PTGES2	80142	prostaglandin E synthase 2	positive regulation of transcription, DNA-templated	Biological process	-
SLC35C1	55343	solute carrier family 35 (GDP-fucose transporter), member C1	antiporter activity	Molecular function	-
IL12B	3593	interleukin 12B	positive regulation of activated T cell proliferation	Biological process	11114383
TH	7054	tyrosine hydroxylase	isoquinoline alkaloid metabolic process	Biological process	-
SET	6418	SET nuclear proto-oncogene	protein phosphatase inhibitor activity	Molecular function	8626647
NPBWR1	2831	neuropeptides B/W receptor 1	plasma membrane	Cellular component	-
PDGFRA	5156	platelet-derived growth factor receptor, alpha polypeptide	platelet-derived growth factor receptor binding	Molecular function	2542288
APOA4	337	apolipoprotein A-IV	extracellular exosome	Cellular component	23376485
GIPR	2696	gastric inhibitory polypeptide receptor	generation of precursor metabolites and energy	Biological process	7556958
ZNF260	339324	zinc finger protein 260	cytoplasm	Cellular component	-
TMC6	11322	transmembrane channel-like 6	biological_process	Biological process	-
UPF2	26019	UPF2 regulator of nonsense transcripts homolog (yeast)	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Biological process	16488880
ABL2	27	ABL proto-oncogene 2, non-receptor tyrosine kinase	epidermal growth factor receptor signaling pathway	Biological process	-
ALDH1B1	219	aldehyde dehydrogenase 1 family, member B1	oxidation-reduction process	Biological process	-
EGFLAM	133584	EGF-like, fibronectin type III and laminin G domains	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan	Biological process	-
C11orf54	28970	chromosome 11 open reading frame 54	protein binding	Molecular function	16189514
KRTDAP	388533	keratinocyte differentiation-associated protein	extracellular region	Cellular component	-
TSKS	60385	testis-specific serine kinase substrate	protein kinase binding	Molecular function	18533145
TMPRSS11B	132724	transmembrane protease, serine 11B	biological_process	Biological process	-
ADIPOQ	9370	adiponectin, C1Q and collagen domain containing	membrane hyperpolarization	Biological process	-
PDE1C	5137	phosphodiesterase 1C, calmodulin-dependent 70kDa	calmodulin binding	Molecular function	-
TLR2	7097	toll-like receptor 2	positive regulation of interleukin-10 production	Biological process	-
PNPT1	87178	polyribonucleotide nucleotidyltransferase 1	mitochondrial RNA catabolic process	Biological process	18501193
BLOC1S2	282991	biogenesis of lysosomal organelles complex-1, subunit 2	centrosome	Cellular component	-
ZNF395	55893	zinc finger protein 395	metal ion binding	Molecular function	-
BMP1	649	bone morphogenetic protein 1	cytokine activity	Molecular function	-
MEIS3	56917	Meis homeobox 3	sequence-specific DNA binding	Molecular function	17178831
RAC1	5879	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	trans-Golgi network	Cellular component	12915445
CEACAM5	1048	carcinoembryonic antigen-related cell adhesion molecule 5	extracellular exosome	Cellular component	19056867
GPC6	10082	glypican 6	carbohydrate metabolic process	Biological process	-
TP53I3	9540	tumor protein p53 inducible protein 3	protein homodimerization activity	Molecular function	19349281
TEC	7006	tec protein tyrosine kinase	peptidyl-tyrosine phosphorylation	Biological process	10518561
CDH5	1003	cadherin 5, type 2 (vascular endothelium)	cell-cell junction	Cellular component	19996314
AQP1	358	aquaporin 1 (Colton blood group)	cellular response to mechanical stimulus	Biological process	19268465
KIF2C	11004	kinesin family member 2C	microtubule plus-end binding	Molecular function	19632184
PYCARD	29108	PYD and CARD domain containing	defense response to Gram-negative bacterium	Biological process	16982856
KLF6	1316	Kruppel-like factor 6	metal ion binding	Molecular function	-
UNK	85451	unkempt family zinc finger	polysome	Cellular component	25737280
DOLK	22845	dolichol kinase	endoplasmic reticulum membrane	Cellular component	-
CDON	50937	cell adhesion associated, oncogene regulated	cerebral cortex development	Biological process	-
OXTR	5021	oxytocin receptor	maternal process involved in parturition	Biological process	-
CDK6	1021	cyclin-dependent kinase 6	negative regulation of cell differentiation	Biological process	16294322
DGKQ	1609	diacylglycerol kinase, theta 110kDa	cytoskeleton	Cellular component	10066731
AKR1C3	8644	aldo-keto reductase family 1, member C3	prostaglandin metabolic process	Biological process	9792917
PPARD	5467	peroxisome proliferator-activated receptor delta	positive regulation of fat cell differentiation	Biological process	10991946
AQP3	360	aquaporin 3 (Gill blood group)	integral component of plasma membrane	Cellular component	-
RPS6KB1	6198	ribosomal protein S6 kinase, 70kDa, polypeptide 1	response to glucose	Biological process	-
NDEL1	81565	nudE neurodevelopment protein 1-like 1	inner cell mass cell proliferation	Biological process	-
DR1	1810	down-regulator of transcription 1, TBP-binding (negative cofactor 2)	transcription, DNA-templated	Biological process	-
DPM3	54344	dolichyl-phosphate mannosyltransferase polypeptide 3	protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan	Biological process	16280320
ASAH2	56624	N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2	mitochondrion	Cellular component	10781606
CDKN1A	1026	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	response to organonitrogen compound	Biological process	-
APOA5	116519	apolipoprotein A-V	lipid transport	Biological process	15178420
C2CD4D	100191040	C2 calcium-dependent domain containing 4D	calcium ion-dependent exocytosis of neurotransmitter	Biological process	-
PRMT2	3275	protein arginine methyltransferase 2	histone arginine methylation	Biological process	-
CSF2	1437	colony stimulating factor 2 (granulocyte-macrophage)	positive regulation of tyrosine phosphorylation of Stat5 protein	Biological process	9722506
TAL2	6887	T-cell acute lymphocytic leukemia 2	post-embryonic development	Biological process	-
PALM	5064	paralemmin	negative regulation of dopamine receptor signaling pathway	Biological process	16386234
BLNK	29760	B-cell linker	transmembrane receptor protein tyrosine kinase signaling pathway	Biological process	9697839
RIMS1	22999	regulating synaptic membrane exocytosis 1	poly(A) RNA binding	Molecular function	22658674
APOE	348	apolipoprotein E	lipoprotein biosynthetic process	Biological process	-
AS3MT	57412	arsenite methyltransferase	arsonoacetate metabolic process	Biological process	-
ATP6V1G1	9550	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1	interaction with host	Biological process	-
TRHDE	29953	thyrotropin-releasing hormone degrading enzyme	integral component of plasma membrane	Cellular component	10491199
CRH	1392	corticotropin releasing hormone	cellular response to dexamethasone stimulus	Biological process	-
JADE1	79960	jade family PHD finger 1	plasma membrane	Cellular component	23001567
RFK	55312	riboflavin kinase	riboflavin biosynthetic process	Biological process	12623014
WNK4	65266	WNK lysine deficient protein kinase 4	negative regulation of pancreatic juice secretion	Biological process	-
EPB41L1	2036	erythrocyte membrane protein band 4.1-like 1	extrinsic component of membrane	Cellular component	-
DMRT1	1761	doublesex and mab-3 related transcription factor 1	transcription, DNA-templated	Biological process	-
MAP6	4135	microtubule-associated protein 6	microtubule binding	Molecular function	-
TBX1	6899	T-box 1	embryonic viscerocranium morphogenesis	Biological process	14585638
MRPS36	92259	mitochondrial ribosomal protein S36	mitochondrial small ribosomal subunit	Cellular component	11279123
PRMT3	10196	protein arginine methyltransferase 3	protein-arginine N-methyltransferase activity	Molecular function	9642256
OPRL1	4987	opiate receptor-like 1	nociceptin receptor activity	Molecular function	12568343
GPR50	9248	G protein-coupled receptor 50	G-protein coupled receptor activity	Molecular function	8647286
CA4	762	carbonic anhydrase IV	perinuclear region of cytoplasm	Cellular component	17409381
ADI1	55256	acireductone dioxygenase 1	plasma membrane	Cellular component	14718544
TARS2	80222	threonyl-tRNA synthetase 2, mitochondrial (putative)	tRNA aminoacylation for protein translation	Biological process	-
H2AFY	9555	H2A histone family, member Y	DNA binding	Molecular function	9714746
STRA6	64220	stimulated by retinoic acid 6	pulmonary valve morphogenesis	Biological process	17273977
BPIFA1	51297	BPI fold containing family A, member 1	molecular_function	Molecular function	-
RPS7	6201	ribosomal protein S7	translational elongation	Biological process	-
RXRA	6256	retinoid X receptor, alpha	embryo implantation	Biological process	-
DHFRP1	573971	dihydrofolate reductase pseudogene 1	one-carbon metabolic process	Biological process	-
APOA2	336	apolipoprotein A-II	cholesterol efflux	Biological process	11162594
ZNF502	91392	zinc finger protein 502	transcription, DNA-templated	Biological process	-
CCL23	6368	chemokine (C-C motif) ligand 23	cellular calcium ion homeostasis	Biological process	9886417
PAX6	5080	paired box 6	cerebral cortex regionalization	Biological process	-
NDUFS3	4722	NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)	negative regulation of cell growth	Biological process	16826196
RPL35A	6165	ribosomal protein L35a	mitochondrion	Cellular component	-
TFAP2E	339488	transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
CASC3	22794	cancer susceptibility candidate 3	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Biological process	-
BDH1	622	3-hydroxybutyrate dehydrogenase, type 1	nucleoplasm	Cellular component	-
PRSS12	8492	protease, serine, 12 (neurotrypsin, motopsin)	axon	Cellular component	-
GCHFR	2644	GTP cyclohydrolase I feedback regulator	cytosol	Cellular component	-
PDS5B	23047	PDS5 cohesin associated factor B	mitotic sister chromatid cohesion	Biological process	15855230
AGPAT2	10555	1-acylglycerol-3-phosphate O-acyltransferase 2	epidermis development	Biological process	-
CDKN2D	1032	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	response to vitamin D	Biological process	16322758
GAL3ST1	9514	galactose-3-O-sulfotransferase 1	spermatogenesis	Biological process	-
JAK2	3717	Janus kinase 2	protein tyrosine kinase activity	Molecular function	-
BACE2	25825	beta-site APP-cleaving enzyme 2	aspartic-type endopeptidase activity	Molecular function	10591213
EIF3L	51386	eukaryotic translation initiation factor 3, subunit L	formation of translation preinitiation complex	Biological process	-
UXS1	80146	UDP-glucuronate decarboxylase 1	NAD+ binding	Molecular function	23072385
PGAP2	27315	post-GPI attachment to proteins 2	integral component of membrane	Cellular component	-
ONECUT1	3175	one cut homeobox 1	nucleus	Cellular component	-
EPO	2056	erythropoietin	positive regulation of protein kinase activity	Biological process	-
DMP1	1758	dentin matrix acidic phosphoprotein 1	positive regulation of cell-substrate adhesion	Biological process	-
BORA	79866	bora, aurora kinase A activator	cell division	Biological process	-
TSC2	7249	tuberous sclerosis 2	cytosol	Cellular component	-
ITGA2	3673	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	positive regulation of transmission of nerve impulse	Biological process	-
TOP1MT	116447	topoisomerase (DNA) I, mitochondrial	mitochondrial nucleoid	Cellular component	18063578
NACAD	23148	NAC alpha domain containing	nucleus	Cellular component	-
CNGA3	1261	cyclic nucleotide gated channel alpha 3	transmembrane transporter complex	Cellular component	24164424
YAP1	10413	Yes-associated protein 1	paraxial mesoderm development	Biological process	-
LST1	7940	leukocyte specific transcript 1	negative regulation of lymphocyte proliferation	Biological process	10706707
TMCO6	55374	transmembrane and coiled-coil domains 6	protein binding	Molecular function	25416956
SRPX2	27286	sushi-repeat containing protein, X-linked 2	excitatory synapse	Cellular component	-
UBTF	7343	upstream binding transcription factor, RNA polymerase I	chromatin binding	Molecular function	-
BAP1	8314	BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)	regulation of cell growth	Biological process	19815555
ESRRA	2101	estrogen-related receptor alpha	steroid hormone receptor activity	Molecular function	-
ZNF492	57615	zinc finger protein 492	DNA binding	Molecular function	-
HAPLN1	1404	hyaluronan and proteoglycan link protein 1	extracellular region	Cellular component	-
SNRPF	6636	small nuclear ribonucleoprotein polypeptide F	spliceosomal snRNP assembly	Biological process	-
ANK1	286	ankyrin 1, erythrocytic	axon guidance	Biological process	-
ERC1	23085	ELKS/RAB6-interacting/CAST family member 1	cytoplasm	Cellular component	15218148
TYROBP	7305	TYRO protein tyrosine kinase binding protein	cell surface	Cellular component	15294961
SAMHD1	25939	SAM domain and HD domain 1	RNA binding	Molecular function	22461318
HIST1H3H	8357	histone cluster 1, H3h	small GTPase mediated signal transduction	Biological process	-
SLC11A1	6556	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1	transmembrane transport	Biological process	-
PDGFA	5154	platelet-derived growth factor alpha polypeptide	neurotrophin TRK receptor signaling pathway	Biological process	-
TSC1	7248	tuberous sclerosis 1	hippocampus development	Biological process	-
SLC9A3R2	9351	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2	protein C-terminus binding	Molecular function	11786550
PINK1	65018	PTEN induced putative kinase 1	cell body	Cellular component	16702191
CALM2	805	calmodulin 2 (phosphorylase kinase, delta)	extracellular exosome	Cellular component	20458337
MDK	4192	midkine (neurite growth-promoting factor 2)	response to glucocorticoid	Biological process	-
ZKSCAN8	7745	zinc finger with KRAB and SCAN domains 8	nucleus	Cellular component	-
PINK1	65018	PTEN induced putative kinase 1	astrocyte projection	Cellular component	16702191
SNRPN	6638	small nuclear ribonucleoprotein polypeptide N	U2 snRNP	Cellular component	-
PPTC7	160760	PTC7 protein phosphatase homolog (S. cerevisiae)	mitochondrion	Cellular component	-
LEF1	51176	lymphoid enhancer-binding factor 1	negative regulation of interleukin-13 production	Biological process	18445004
ZP4	57829	zona pellucida glycoprotein 4	single fertilization	Biological process	-
MAEA	10296	macrophage erythroblast attacher	integral component of plasma membrane	Cellular component	9763581
WNT2	7472	wingless-type MMTV integration site family member 2	neuron differentiation	Biological process	-
RAB9B	51209	RAB9B, member RAS oncogene family	late endosome	Cellular component	-
HMGXB3	22993	HMG box domain containing 3	nucleus	Cellular component	-
ITGAM	3684	integrin, alpha M (complement component 3 receptor 3 subunit)	cell surface	Cellular component	19234460
CDKN1A	1026	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	negative regulation of phosphorylation	Biological process	10208428
RANGAP1	5905	Ran GTPase activating protein 1	protein binding	Molecular function	17000644
HSP90AA1	3320	heat shock protein 90kDa alpha (cytosolic), class A member 1	nitric-oxide synthase regulator activity	Molecular function	15937123
CYBB	1536	cytochrome b-245, beta polypeptide	neuronal cell body	Cellular component	-
MAN1A2	10905	mannosidase, alpha, class 1A, member 2	cellular protein metabolic process	Biological process	-
ECI2	10455	enoyl-CoA delta isomerase 2	nucleoplasm	Cellular component	-
MAP1LC3C	440738	microtubule-associated protein 1 light chain 3 gamma	pre-autophagosomal structure	Cellular component	-
TPPP3	51673	tubulin polymerization-promoting protein family member 3	tubulin binding	Molecular function	17105200
KCNQ2	3785	potassium channel, voltage gated KQT-like subfamily Q, member 2	voltage-gated potassium channel activity	Molecular function	9677360
MRPL10	124995	mitochondrial ribosomal protein L10	protein binding	Molecular function	25416956
KDM3A	55818	lysine (K)-specific demethylase 3A	chromatin organization	Biological process	-
FRAT2	23401	frequently rearranged in advanced T-cell lymphomas 2	cellular_component	Cellular component	-
STRA8	346673	stimulated by retinoic acid 8	regulation of organ growth	Biological process	-
RBMS3	27303	RNA binding motif, single stranded interacting protein 3	cytoplasm	Cellular component	-
CCK	885	cholecystokinin	signal transduction	Biological process	10320330
PDE1B	5153	phosphodiesterase 1B, calmodulin-dependent	cytosol	Cellular component	-
IRF3	3661	interferon regulatory factor 3	nucleoplasm	Cellular component	-
HLCS	3141	holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)	biotin binding	Molecular function	14613969
PRKACG	5568	protein kinase, cAMP-dependent, catalytic, gamma	gluconeogenesis	Biological process	-
HARS2	23438	histidyl-tRNA synthetase 2, mitochondrial	mitochondrial matrix	Cellular component	-
FAN1	22909	FANCD2/FANCI-associated nuclease 1	intercellular bridge	Cellular component	-
TAL1	6886	T-cell acute lymphocytic leukemia 1	RNA polymerase II core promoter sequence-specific DNA binding	Molecular function	-
OR8G2	26492	olfactory receptor, family 8, subfamily G, member 2	G-protein coupled receptor signaling pathway	Biological process	-
UQCRH	7388	ubiquinol-cytochrome c reductase hinge protein	cellular metabolic process	Biological process	-
MDN1	23195	MDN1, midasin homolog (yeast)	nucleolus	Cellular component	-
OSBPL6	114880	oxysterol binding protein-like 6	perinuclear endoplasmic reticulum	Cellular component	14593528
CACNA1B	774	calcium channel, voltage-dependent, N type, alpha 1B subunit	synaptic transmission	Biological process	-
MYF5	4617	myogenic factor 5	positive regulation of myoblast differentiation	Biological process	-
GJA1	2697	gap junction protein, alpha 1, 43kDa	mitochondrial outer membrane	Cellular component	-
IL18	3606	interleukin 18	cytosol	Cellular component	-
OR7G3	390883	olfactory receptor, family 7, subfamily G, member 3	G-protein coupled receptor activity	Molecular function	-
PCDHB2	56133	protocadherin beta 2	homophilic cell adhesion via plasma membrane adhesion molecules	Biological process	-
WEE1	7465	WEE1 G2 checkpoint kinase	G1/S transition of mitotic cell cycle	Biological process	-
PSEN1	5663	presenilin 1	negative regulation of epidermal growth factor-activated receptor activity	Biological process	-
GBF1	8729	golgi brefeldin A resistant guanine nucleotide exchange factor 1	Golgi apparatus	Cellular component	-
ZNF304	57343	zinc finger protein 304	DNA binding	Molecular function	-
FST	10468	follistatin	BMP signaling pathway	Biological process	-
ARF1	375	ADP-ribosylation factor 1	small molecule metabolic process	Biological process	-
NR2F1	7025	nuclear receptor subfamily 2, group F, member 1	retinoic acid-responsive element binding	Molecular function	-
AAK1	22848	AP2 associated kinase 1	protein serine/threonine kinase activity	Molecular function	-
MYC	4609	v-myc avian myelocytomatosis viral oncogene homolog	negative regulation of stress-activated MAPK cascade	Biological process	-
PHOX2B	8929	paired-like homeobox 2b	glial cell differentiation	Biological process	-
MGMT	4255	O-6-methylguanine-DNA methyltransferase	DNA-methyltransferase activity	Molecular function	2405387
KLRC4-KLRK1	100528032	KLRC4-KLRK1 readthrough	negative regulation of GTPase activity	Biological process	22585739
PEX11B	8799	peroxisomal biogenesis factor 11 beta	protein homodimerization activity	Molecular function	20826455
VPRBP	9730	Vpr (HIV-1) binding protein	histone H2A-T120 phosphorylation	Biological process	24140421
UGT1A1	54658	UDP glucuronosyltransferase 1 family, polypeptide A1	integral component of plasma membrane	Cellular component	-
TTYH1	57348	tweety family member 1	plasma membrane	Cellular component	-
IDH3G	3421	isocitrate dehydrogenase 3 (NAD+) gamma	mitochondrial matrix	Cellular component	-
SSBP1	6742	single-stranded DNA binding protein 1, mitochondrial	mitochondrion organization	Biological process	-
SPRN	503542	shadow of prion protein homolog (zebrafish)	anchored component of membrane	Cellular component	-
RHBDL1	9028	rhomboid, veinlet-like 1 (Drosophila)	signal transduction	Biological process	9662444
CRLF3	51379	cytokine receptor-like factor 3	positive regulation of transcription, DNA-templated	Biological process	19427400
FGF10	2255	fibroblast growth factor 10	positive regulation of ERK1 and ERK2 cascade	Biological process	14975937
PDE1A	5136	phosphodiesterase 1A, calmodulin-dependent	cGMP binding	Molecular function	-
IFNA8	3445	interferon, alpha 8	regulation of type I interferon-mediated signaling pathway	Biological process	-
DLL1	28514	delta-like 1 (Drosophila)	Notch signaling pathway	Biological process	-
ZNF56	7608	zinc finger protein 56	nucleus	Cellular component	-
CARM1	10498	coactivator-associated arginine methyltransferase 1	beta-catenin binding	Molecular function	16344550
ACTR6	64431	ARP6 actin-related protein 6 homolog (yeast)	cytoskeleton	Cellular component	-
HPX	3263	hemopexin	extracellular exosome	Cellular component	19056867
RUNX1	861	runt-related transcription factor 1	sequence-specific DNA binding transcription factor activity	Molecular function	14970218
ENO1	2023	enolase 1, (alpha)	cytoplasm	Cellular component	-
LRP1	4035	low density lipoprotein receptor-related protein 1	negative regulation of smooth muscle cell migration	Biological process	-
PTPRZ1	5803	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	integral component of plasma membrane	Cellular component	8387522
GGT1	2678	gamma-glutamyltransferase 1	glutathione catabolic process	Biological process	17924658
PNP	4860	purine nucleoside phosphorylase	small molecule metabolic process	Biological process	-
RARB	5915	retinoic acid receptor, beta	positive regulation of neuron differentiation	Biological process	-
CNGB1	1258	cyclic nucleotide gated channel beta 1	cGMP binding	Molecular function	24164424
ERCC5	2073	excision repair cross-complementation group 5	nucleotide-excision repair	Biological process	-
IL18	3606	interleukin 18	sleep	Biological process	11506998
STAT5A	6776	signal transducer and activator of transcription 5A	cytosol	Cellular component	-
COMT	1312	catechol-O-methyltransferase	negative regulation of renal sodium excretion	Biological process	-
SLC8A1	6546	solute carrier family 8 (sodium/calcium exchanger), member 1	post-embryonic development	Biological process	-
AARD	441376	alanine and arginine rich domain containing protein	lung development	Biological process	-
NKX2-2	4821	NK2 homeobox 2	transcription factor binding	Molecular function	-
BICD1	636	bicaudal D homolog 1 (Drosophila)	cytoskeleton	Cellular component	9367685
AKR1C3	8644	aldo-keto reductase family 1, member C3	renal absorption	Biological process	16157291
ARID3C	138715	AT rich interactive domain 3C (BRIGHT-like)	cytoplasm	Cellular component	-
PSME4	23198	proteasome (prosome, macropain) activator subunit 4	nuclear speck	Cellular component	-
SIRT2	22933	sirtuin 2	juxtaparanode region of axon	Cellular component	-
RALB	5899	v-ral simian leukemia viral oncogene homolog B	autophagosome	Cellular component	24056301
ACOT11	26027	acyl-CoA thioesterase 11	acyl-CoA hydrolase activity	Molecular function	11696000
CYGB	114757	cytoglobin	oxygen transporter activity	Molecular function	11919282
DICER1	23405	dicer 1, ribonuclease type III	regulation of muscle cell apoptotic process	Biological process	-
ACER3	55331	alkaline ceramidase 3	sphingolipid metabolic process	Biological process	-
UVRAG	7405	UV radiation resistance associated	late endosome	Cellular component	19270696
GABRA5	2558	gamma-aminobutyric acid (GABA) A receptor, alpha 5	associative learning	Biological process	-
ABCD1	215	ATP-binding cassette, sub-family D (ALD), member 1	protein homodimerization activity	Molecular function	17609205
TLN2	83660	talin 2	insulin receptor binding	Molecular function	-
PAK1	5058	p21 protein (Cdc42/Rac)-activated kinase 1	protein binding	Molecular function	11950598
ZNF234	10780	zinc finger protein 234	transcription, DNA-templated	Biological process	-
POM121	9883	POM121 transmembrane nucleoporin	carbohydrate metabolic process	Biological process	-
ADH4	127	alcohol dehydrogenase 4 (class II), pi polypeptide	retinol metabolic process	Biological process	16787387
GSK3A	2931	glycogen synthase kinase 3 alpha	cytosol	Cellular component	11035810
STC2	8614	stanniocalcin 2	embryo implantation	Biological process	-
ITGB3	3690	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	identical protein binding	Molecular function	11606749
TMEM183B	653659	transmembrane protein 183B	integral component of membrane	Cellular component	-
WIPF2	147179	WAS/WASL interacting protein family, member 2	innate immune response	Biological process	-
RPS3	6188	ribosomal protein S3	nucleus	Cellular component	21399639
APOA1	335	apolipoprotein A-I	cholesterol import	Biological process	14718538
UBE2R2	54926	ubiquitin-conjugating enzyme E2R 2	ubiquitin protein ligase binding	Molecular function	-
PDXK	8566	pyridoxal (pyridoxine, vitamin B6) kinase	pyridoxal phosphate biosynthetic process	Biological process	10987144
PSMC3	5702	proteasome (prosome, macropain) 26S subunit, ATPase, 3	negative regulation of apoptotic process	Biological process	-
CBL	867	Cbl proto-oncogene, E3 ubiquitin protein ligase	negative regulation of epidermal growth factor receptor signaling pathway	Biological process	-
OR2L5	81466	olfactory receptor, family 2, subfamily L, member 5	G-protein coupled receptor signaling pathway	Biological process	-
GSTA1	2938	glutathione S-transferase alpha 1	glutathione derivative biosynthetic process	Biological process	-
SCIN	85477	scinderin	cytoplasm	Cellular component	-
OGG1	4968	8-oxoguanine DNA glycosylase	nuclear speck	Cellular component	17148573
ROBO2	6092	roundabout, axon guidance receptor, homolog 2 (Drosophila)	axon guidance	Biological process	-
PDLIM4	8572	PDZ and LIM domain 4	protein binding	Molecular function	10826496
TFAP2B	7021	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	ductus arteriosus closure	Biological process	-
CHD2	1106	chromodomain helicase DNA binding protein 2	cellular response to DNA damage stimulus	Biological process	-
KCTD7	154881	potassium channel tetramerization domain containing 7	protein homooligomerization	Biological process	-
SNX6	58533	sorting nexin 6	regulation of histamine secretion by mast cell	Biological process	18253931
FGFR3	2261	fibroblast growth factor receptor 3	negative regulation of developmental growth	Biological process	20582225
CAMSAP1	157922	calmodulin regulated spectrin-associated protein 1	cytoskeleton organization	Biological process	21834987
NDEL1	81565	nudE neurodevelopment protein 1-like 1	kinesin complex	Cellular component	-
CSNK2A2	1459	casein kinase 2, alpha prime polypeptide	PcG protein complex	Cellular component	21282530
CYP2R1	120227	cytochrome P450, family 2, subfamily R, polypeptide 1	intracellular membrane-bounded organelle	Cellular component	-
P2RX4	5025	purinergic receptor P2X, ligand gated ion channel, 4	tissue homeostasis	Biological process	17264311
RGS7BP	401190	regulator of G-protein signaling 7 binding protein	cytoplasm	Cellular component	-
ELMOD2	255520	ELMO/CED-12 domain containing 2	positive regulation of GTPase activity	Biological process	-
B4GALNT2	124872	beta-1,4-N-acetyl-galactosaminyl transferase 2	negative regulation of cell-cell adhesion	Biological process	16024623
LRRC16A	55604	leucine rich repeat containing 16A	positive regulation of substrate adhesion-dependent cell spreading	Biological process	16054028
ARL8A	127829	ADP-ribosylation factor-like 8A	membrane	Cellular component	19946888
IKBKG	8517	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	cellular response to DNA damage stimulus	Biological process	14651848
NKX3-1	4824	NK3 homeobox 1	MADS box domain binding	Molecular function	-
HNRNPC	3183	heterogeneous nuclear ribonucleoprotein C (C1/C2)	poly(U) RNA binding	Molecular function	16010978
GLI3	2737	GLI family zinc finger 3	anterior semicircular canal development	Biological process	-
SRP19	6728	signal recognition particle 19kDa	cytoplasm	Cellular component	-
GPR65	8477	G protein-coupled receptor 65	G-protein coupled receptor activity	Molecular function	15618224
HLA-DRA	3122	major histocompatibility complex, class II, DR alpha	extracellular exosome	Cellular component	11487543
ZIC3	7547	Zic family member 3	sequence-specific DNA binding transcription factor activity	Molecular function	17764085
UTS2	10911	urotensin 2	positive regulation of cytosolic calcium ion concentration	Biological process	-
NUPL2	11097	nucleoporin like 2	cytosol	Cellular component	-
PLK4	10733	polo-like kinase 4	cytosol	Cellular component	-
TAL1	6886	T-cell acute lymphocytic leukemia 1	positive regulation of transcription, DNA-templated	Biological process	20028976
RFC5	5985	replication factor C (activator 1) 5, 36.5kDa	telomere maintenance via recombination	Biological process	-
PVRL1	5818	poliovirus receptor-related 1 (herpesvirus entry mediator C)	intracellular membrane-bounded organelle	Cellular component	-
CIT	11113	citron rho-interacting serine/threonine kinase	protein binding	Molecular function	16431929
DGKE	8526	diacylglycerol kinase, epsilon 64kDa	diacylglycerol kinase activity	Molecular function	-
USP1	7398	ubiquitin specific peptidase 1	response to UV	Biological process	18082604
FUK	197258	fucokinase	fucokinase activity	Molecular function	12056818
NOD2	64127	nucleotide-binding oligomerization domain containing 2	activation of MAPK activity	Biological process	-
LAMA4	3910	laminin, alpha 4	regulation of embryonic development	Biological process	-
OR8K1	390157	olfactory receptor, family 8, subfamily K, member 1	G-protein coupled receptor signaling pathway	Biological process	-
LPIN3	64900	lipin 3	phosphatidate phosphatase activity	Molecular function	-
LTA4H	4048	leukotriene A4 hydrolase	aminopeptidase activity	Molecular function	15078870
PRKCG	5582	protein kinase C, gamma	synaptic membrane	Cellular component	-
NOD1	10392	nucleotide-binding oligomerization domain containing 1	toll-like receptor TLR1:TLR2 signaling pathway	Biological process	-
GATA3	2625	GATA binding protein 3	pro-T cell differentiation	Biological process	-
PIK3CD	5293	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	epidermal growth factor receptor signaling pathway	Biological process	-
RPS6KA6	27330	ribosomal protein S6 kinase, 90kDa, polypeptide 6	protein kinase activity	Molecular function	10644430
PTPRN	5798	protein tyrosine phosphatase, receptor type, N	response to glucose	Biological process	-
PIK3CA	5290	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	activation of mitophagy in response to mitochondrial depolarization	Biological process	22020285
CEBPG	1054	CCAAT/enhancer binding protein (C/EBP), gamma	positive regulation of sequence-specific DNA binding transcription factor activity	Biological process	7665092
KIAA1715	80856	KIAA1715	endoplasmic reticulum tubular network	Cellular component	-
AGER	177	advanced glycosylation end product-specific receptor	receptor activity	Molecular function	8751438
ITGA10	8515	integrin, alpha 10	axon guidance	Biological process	-
CRTC2	200186	CREB regulated transcription coactivator 2	toxin transport	Biological process	-
PLCB3	5331	phospholipase C, beta 3 (phosphatidylinositol-specific)	synaptic transmission	Biological process	-
NR2E3	10002	nuclear receptor subfamily 2, group E, member 3	negative regulation of cell proliferation	Biological process	-
CYP26B1	56603	cytochrome P450, family 26, subfamily B, polypeptide 1	retinoic acid receptor signaling pathway	Biological process	-
NUP62	23636	nucleoporin 62kDa	negative regulation of MAP kinase activity	Biological process	-
BMPR2	659	bone morphogenetic protein receptor, type II (serine/threonine kinase)	positive regulation of BMP signaling pathway	Biological process	17992660
LRP5	4041	low density lipoprotein receptor-related protein 5	osteoblast development	Biological process	-
PBRM1	55193	polybromo 1	BAF-type complex	Cellular component	12368262
TRIM55	84675	tripartite motif containing 55	identical protein binding	Molecular function	22493164
KLF2	10365	Kruppel-like factor 2	cellular response to hydrogen peroxide	Biological process	-
MSRB3	253827	methionine sulfoxide reductase B3	endoplasmic reticulum	Cellular component	14699060
SLC27A1	376497	solute carrier family 27 (fatty acid transporter), member 1	phosphatidic acid biosynthetic process	Biological process	19523918
OR6N2	81442	olfactory receptor, family 6, subfamily N, member 2	G-protein coupled receptor activity	Molecular function	-
GEM	2669	GTP binding protein overexpressed in skeletal muscle	mitotic spindle	Cellular component	22964304
XPO7	23039	exportin 7	cytoplasm	Cellular component	11071879
F2	2147	coagulation factor II (thrombin)	regulation of gene expression	Biological process	-
SH2D5	400745	SH2 domain containing 5	postsynaptic membrane	Cellular component	-
TSC1	7248	tuberous sclerosis 1	protein heterooligomerization	Biological process	-
G6PC2	57818	glucose-6-phosphatase, catalytic, 2	endoplasmic reticulum membrane	Cellular component	-
GRHL3	57822	grainyhead-like 3 (Drosophila)	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
CELF2	10659	CUGBP, Elav-like family member 2	cytoplasm	Cellular component	-
QARS	5859	glutaminyl-tRNA synthetase	protein binding	Molecular function	24656866
ECT2L	345930	epithelial cell transforming 2 like	Rho guanyl-nucleotide exchange factor activity	Molecular function	-
RTN3	10313	reticulon 3	vesicle-mediated transport	Biological process	-
VPS13D	55187	vacuolar protein sorting 13 homolog D (S. cerevisiae)	extrinsic component of membrane	Cellular component	-
TOR1A	1861	torsin family 1, member A (torsin A)	wound healing, spreading of cells	Biological process	-
PKD1	5310	polycystic kidney disease 1 (autosomal dominant)	liver development	Biological process	-
SPEN	23013	spen family transcriptional repressor	nucleotide binding	Molecular function	-
SCN2B	6327	sodium channel, voltage gated, type II beta subunit	cardiac muscle cell action potential involved in contraction	Biological process	19808477
AKT1	207	v-akt murine thymoma viral oncogene homolog 1	protein import into nucleus, translocation	Biological process	16280327
PLK2	10769	polo-like kinase 2	protein serine/threonine kinase activity	Molecular function	19001868
COL14A1	7373	collagen, type XIV, alpha 1	poly(A) RNA binding	Molecular function	22658674
RLF	6018	rearranged L-myc fusion	positive regulation of transcription, DNA-templated	Biological process	8545128
RCN3	57333	reticulocalbin 3, EF-hand calcium binding domain	protein binding	Molecular function	16189514
ZNF234	10780	zinc finger protein 234	regulation of transcription, DNA-templated	Biological process	-
FIS1	51024	fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)	protein homooligomerization	Biological process	18845145
OR1E3	8389	olfactory receptor, family 1, subfamily E, member 3 (gene/pseudogene)	olfactory receptor activity	Molecular function	-
ABCC9	10060	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	signal transduction	Biological process	8826984
POLR2J	5439	polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa	transcription elongation from RNA polymerase II promoter	Biological process	-
ROCK2	9475	Rho-associated, coiled-coil containing protein kinase 2	positive regulation of centrosome duplication	Biological process	-
RNMT	8731	RNA (guanine-7-) methyltransferase	nucleus	Cellular component	9790902
STARD13	90627	StAR-related lipid transfer (START) domain containing 13	cytosol	Cellular component	-
PPP1R8	5511	protein phosphatase 1, regulatory subunit 8	nucleus	Cellular component	7499293
SETD6	79918	SET domain containing 6	peptidyl-lysine monomethylation	Biological process	21131967
CTSB	1508	cathepsin B	extracellular matrix organization	Biological process	-
GTF2E1	2960	general transcription factor IIE, polypeptide 1, alpha 56kDa	viral process	Biological process	-
DGAT1	8694	diacylglycerol O-acyltransferase 1	triglyceride metabolic process	Biological process	9756920
TNNC1	7134	troponin C type 1 (slow)	calcium-dependent protein binding	Molecular function	7957210
SCX	642658	scleraxis basic helix-loop-helix transcription factor	tendon cell differentiation	Biological process	-
TGFB1	7040	transforming growth factor, beta 1	negative regulation of skeletal muscle tissue development	Biological process	9770491
EPS8	2059	epidermal growth factor receptor pathway substrate 8	dendritic cell migration	Biological process	-
SIGIRR	59307	single immunoglobulin and toll-interleukin 1 receptor (TIR) domain	negative regulation of chemokine biosynthetic process	Biological process	-
NEK9	91754	NIMA-related kinase 9	protein kinase binding	Molecular function	19001501
CDH13	1012	cadherin 13	positive regulation of positive chemotaxis	Biological process	16013438
OR14A16	284532	olfactory receptor, family 14, subfamily A, member 16	odorant binding	Molecular function	-
KCNMB4	27345	potassium channel subfamily M regulatory beta subunit 4	plasma membrane	Cellular component	-
UCN	7349	urocortin	corticotropin-releasing hormone receptor 2 binding	Molecular function	-
SMG1	23049	SMG1 phosphatidylinositol 3-kinase-related kinase	phosphatidylinositol phosphorylation	Biological process	11331269
B2M	567	beta-2-microglobulin	ER to Golgi transport vesicle membrane	Cellular component	-
RMDN1	51115	regulator of microtubule dynamics 1	mitochondrion	Cellular component	-
XPO5	57510	exportin 5	pre-miRNA export from nucleus	Biological process	14681208
GIPR	2696	gastric inhibitory polypeptide receptor	plasma membrane	Cellular component	-
FYN	2534	FYN proto-oncogene, Src family tyrosine kinase	positive regulation of protein localization to nucleus	Biological process	-
RARRES2	5919	retinoic acid receptor responder (tazarotene induced) 2	positive regulation of protein phosphorylation	Biological process	17635925
AIF1	199	allograft inflammatory factor 1	cellular response to hydroperoxide	Biological process	-
ZBED1	9189	zinc finger, BED-type containing 1	metabolic process	Biological process	9887332
PRDM4	11108	PR domain containing 4	DNA binding	Molecular function	-
ZBTB14	7541	zinc finger and BTB domain containing 14	metal ion binding	Molecular function	-
MED24	9862	mediator complex subunit 24	nucleus	Cellular component	10235267
NOBOX	135935	NOBOX oogenesis homeobox	cytoplasm	Cellular component	-
MAP2	4133	microtubule-associated protein 2	protein binding	Molecular function	20195357
PADI3	51702	peptidyl arginine deiminase, type III	cytoplasm	Cellular component	-
DIS3	22894	DIS3 exosome endoribonuclease and 3'-5' exoribonuclease	rRNA processing	Biological process	9562621
FYN	2534	FYN proto-oncogene, Src family tyrosine kinase	peptide hormone receptor binding	Molecular function	-
UGT1A5	54579	UDP glucuronosyltransferase 1 family, polypeptide A5	cellular response to hormone stimulus	Biological process	-
TMX1	81542	thioredoxin-related transmembrane protein 1	disulfide oxidoreductase activity	Molecular function	11152479
USH2A	7399	Usher syndrome 2A (autosomal recessive, mild)	maintenance of organ identity	Biological process	15671307
THY1	7070	Thy-1 cell surface antigen	focal adhesion	Cellular component	21423176
OLFM2	93145	olfactomedin 2	extracellular region	Cellular component	21228389
CLTC	1213	clathrin, heavy chain (Hc)	plasma membrane	Cellular component	-
KCNJ10	3766	potassium channel, inwardly rectifying subfamily J, member 10	regulation of sensory perception of pain	Biological process	-
IFNA5	3442	interferon, alpha 5	type I interferon receptor binding	Molecular function	-
PHC2	1912	polyhomeotic homolog 2 (Drosophila)	PcG protein complex	Cellular component	21282530
ARRB1	408	arrestin, beta 1	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	Molecular function	-
LNPEP	4012	leucyl/cystinyl aminopeptidase	female pregnancy	Biological process	8550619
ANGPT1	284	angiopoietin 1	negative regulation of neuron apoptotic process	Biological process	-
NSMAF	8439	neutral sphingomyelinase (N-SMase) activation associated factor	ceramide metabolic process	Biological process	8808629
RIC8B	55188	RIC8 guanine nucleotide exchange factor B	cytoplasm	Cellular component	-
NEUROG3	50674	neurogenin 3	protein dimerization activity	Molecular function	-
CDCA3	83461	cell division cycle associated 3	mitotic nuclear division	Biological process	-
AP3M2	10947	adaptor-related protein complex 3, mu 2 subunit	intracellular protein transport	Biological process	-
MET	4233	MET proto-oncogene, receptor tyrosine kinase	placenta development	Biological process	-
APC	324	adenomatous polyposis coli	dorsal/ventral pattern formation	Biological process	-
ZBTB9	221504	zinc finger and BTB domain containing 9	regulation of transcription, DNA-templated	Biological process	-
CALM2	805	calmodulin 2 (phosphorylase kinase, delta)	regulation of heart rate	Biological process	23040497
NUP214	8021	nucleoporin 214kDa	viral process	Biological process	-
DTNBP1	84062	dystrobrevin binding protein 1	neuron projection development	Biological process	16980328
HIP1R	9026	huntingtin interacting protein 1 related	clathrin-mediated endocytosis	Biological process	-
STK11	6794	serine/threonine kinase 11	magnesium ion binding	Molecular function	12805220
TXNL4A	10907	thioredoxin-like 4A	cell division	Biological process	-
FZD9	8326	frizzled class receptor 9	nervous system development	Biological process	9147651
ARHGAP18	93663	Rho GTPase activating protein 18	GTPase activator activity	Molecular function	-
ACSM5	54988	acyl-CoA synthetase medium-chain family member 5	metal ion binding	Molecular function	-
TGFB3	7043	transforming growth factor, beta 3	plasma membrane	Cellular component	11157754
EPAS1	2034	endothelial PAS domain protein 1	cytosol	Cellular component	-
NDUFAF3	25915	NADH dehydrogenase (ubiquinone) complex I, assembly factor 3	nucleus	Cellular component	-
S100A9	6280	S100 calcium binding protein A9	response to ethanol	Biological process	-
NOTCH1	4851	notch 1	cytosol	Cellular component	-
FARP1	10160	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)	positive regulation of GTPase activity	Biological process	9425278
CYLD	1540	cylindromatosis (turban tumor syndrome)	ubiquitin-specific protease activity	Molecular function	18313383
ITGAE	3682	integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)	metal ion binding	Molecular function	-
ERCC5	2073	excision repair cross-complementation group 5	response to UV-C	Biological process	17208056
FCN1	2219	ficolin (collagen/fibrinogen domain containing) 1	positive regulation of interleukin-8 secretion	Biological process	21037097
IFNG	3458	interferon, gamma	positive regulation of MHC class II biosynthetic process	Biological process	-
JAK2	3717	Janus kinase 2	response to interleukin-12	Biological process	7528775
ABCA9	10350	ATP-binding cassette, sub-family A (ABC1), member 9	ATP binding	Molecular function	-
CFL2	1073	cofilin 2 (muscle)	extracellular exosome	Cellular component	23533145
CKS2	1164	CDC28 protein kinase regulatory subunit 2	cell division	Biological process	-
TUSC2	11334	tumor suppressor candidate 2	inflammatory response	Biological process	-
MAPK1	5594	mitogen-activated protein kinase 1	toll-like receptor TLR6:TLR2 signaling pathway	Biological process	-
B4GALT5	9334	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5	integral component of membrane	Cellular component	-
CACUL1	143384	CDK2-associated, cullin domain 1	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	-
FRG2C	100288801	FSHD region gene 2 family, member C	nucleus	Cellular component	-
SYT5	6861	synaptotagmin V	perinuclear region of cytoplasm	Cellular component	-
XRN2	22803	5'-3' exoribonuclease 2	nuclease activity	Molecular function	10409438
NR4A2	4929	nuclear receptor subfamily 4, group A, member 2	RNA polymerase II core promoter sequence-specific DNA binding	Molecular function	-
RAD51	5888	RAD51 recombinase	double-strand break repair	Biological process	-
GK	2710	glycerol kinase	glucose homeostasis	Biological process	-
VEGFA	7422	vascular endothelial growth factor A	cellular response to hypoxia	Biological process	-
PPIL1	51645	peptidylprolyl isomerase (cyclophilin)-like 1	peptidyl-prolyl cis-trans isomerase activity	Molecular function	-
IZUMO4	113177	IZUMO family member 4	extracellular region	Cellular component	-
FKTN	2218	fukutin	nervous system development	Biological process	9690476
CARS	833	cysteinyl-tRNA synthetase	cysteinyl-tRNA aminoacylation	Biological process	10908348
NPY4R	5540	neuropeptide Y receptor Y4	peptide YY receptor activity	Molecular function	-
UCP2	7351	uncoupling protein 2 (mitochondrial, proton carrier)	response to fatty acid	Biological process	-
ASAH2	56624	N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2	signal transduction	Biological process	10781606
PDLIM2	64236	PDZ and LIM domain 2 (mystique)	nucleus	Cellular component	-
NCOR1	9611	nuclear receptor corepressor 1	spindle microtubule	Cellular component	18326024
BRCC3	79184	BRCA1/BRCA2-containing complex, subunit 3	metallopeptidase activity	Molecular function	17525341
NTN3	4917	netrin 3	positive regulation of muscle cell differentiation	Biological process	-
QARS	5859	glutaminyl-tRNA synthetase	cytoplasm	Cellular component	-
PLCB2	5330	phospholipase C, beta 2	small molecule metabolic process	Biological process	-
IL16	3603	interleukin 16	nucleus	Cellular component	-
ATG16L2	89849	autophagy related 16-like 2 (S. cerevisiae)	autophagosome assembly	Biological process	-
ATP1A2	477	ATPase, Na+/K+ transporting, alpha 2 polypeptide	sodium ion export from cell	Biological process	10636900
PAPPA	5069	pregnancy-associated plasma protein A, pappalysin 1	membrane	Cellular component	-
GLT8D1	55830	glycosyltransferase 8 domain containing 1	metabolic process	Biological process	-
IFNL3	282617	interferon, lambda 3	positive regulation of protein targeting to mitochondrion	Biological process	24270810
BAMBI	25805	BMP and activin membrane-bound inhibitor	positive regulation of canonical Wnt signaling pathway	Biological process	18838381
JUND	3727	jun D proto-oncogene	cellular response to hormone stimulus	Biological process	-
EPO	2056	erythropoietin	cellular response to hypoxia	Biological process	-
APC2	10297	adenomatosis polyposis coli 2	Wnt signaling pathway	Biological process	-
ACACB	32	acetyl-CoA carboxylase beta	carnitine shuttle	Biological process	-
KDR	3791	kinase insert domain receptor	cell junction	Cellular component	-
OAZ3	51686	ornithine decarboxylase antizyme 3	ornithine decarboxylase inhibitor activity	Molecular function	-
SOD3	6649	superoxide dismutase 3, extracellular	extracellular exosome	Cellular component	23376485
ARL14	80117	ADP-ribosylation factor-like 14	GTP binding	Molecular function	-
ATP5D	513	ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit	mitochondrial inner membrane	Cellular component	-
LPAR1	1902	lysophosphatidic acid receptor 1	positive regulation of apoptotic process	Biological process	-
EIF4EBP2	1979	eukaryotic translation initiation factor 4E binding protein 2	cAMP-mediated signaling	Biological process	-
USP32	84669	ubiquitin specific peptidase 32	regulation of proteasomal protein catabolic process	Biological process	-
RYR2	6262	ryanodine receptor 2 (cardiac)	positive regulation of ryanodine-sensitive calcium-release channel activity by adrenergic receptor signaling pathway involved in positive regulation of cardiac muscle contraction	Biological process	-
MAGEA2B	266740	melanoma antigen family A2B	repressing transcription factor binding	Molecular function	16847267
CHADL	150356	chondroadherin-like	negative regulation of collagen fibril organization	Biological process	25451920
CD9	928	CD9 molecule	extracellular space	Cellular component	16502470
GNA13	10672	guanine nucleotide binding protein (G protein), alpha 13	protein binding	Molecular function	10026210
RAD9A	5883	RAD9 homolog A (S. pombe)	protein binding	Molecular function	10359610
CTSB	1508	cathepsin B	protein binding	Molecular function	16237761
SNRPD1	6632	small nuclear ribonucleoprotein D1 polypeptide 16kDa	ncRNA metabolic process	Biological process	-
TBC1D2	55357	TBC1 domain family, member 2	cadherin binding	Molecular function	20116244
CEBPA	1050	CCAAT/enhancer binding protein (C/EBP), alpha	lung development	Biological process	-
SNCG	6623	synuclein, gamma (breast cancer-specific protein 1)	aggressive behavior	Biological process	-
LAX1	54900	lymphocyte transmembrane adaptor 1	Golgi apparatus	Cellular component	-
VGLL1	51442	vestigial-like family member 1	transcription coactivator activity	Molecular function	10518497
FADD	8772	Fas (TNFRSF6)-associated via death domain	positive regulation of proteolysis	Biological process	18387192
SMC3	9126	structural maintenance of chromosomes 3	post-translational protein modification	Biological process	-
PPAT	5471	phosphoribosyl pyrophosphate amidotransferase	purine nucleotide biosynthetic process	Biological process	8106516
BMP4	652	bone morphogenetic protein 4	mesenchymal cell proliferation involved in ureteric bud development	Biological process	-
FGR	2268	FGR proto-oncogene, Src family tyrosine kinase	response to virus	Biological process	3003578
HSP90AA2P	3324	heat shock protein 90kDa alpha (cytosolic), class A member 2, pseudogene	extracellular exosome	Cellular component	23533145
TTC26	79989	tetratricopeptide repeat domain 26	ciliary tip	Cellular component	-
UBA7	7318	ubiquitin-like modifier activating enzyme 7	translesion synthesis	Biological process	-
DARS2	55157	aspartyl-tRNA synthetase 2, mitochondrial	protein homodimerization activity	Molecular function	15779907
NAIP	4671	NLR family, apoptosis inhibitory protein	protein ubiquitination	Biological process	-
HES3	390992	hes family bHLH transcription factor 3	in utero embryonic development	Biological process	-
CRK	1398	v-crk avian sarcoma virus CT10 oncogene homolog	actin cytoskeleton	Cellular component	-
KIAA0196	9897	KIAA0196	cytosol	Cellular component	-
ELOVL2	54898	ELOVL fatty acid elongase 2	fatty acid elongation, polyunsaturated fatty acid	Biological process	12371743
WRN	7486	Werner syndrome, RecQ helicase-like	3'-5' DNA helicase activity	Molecular function	17715146
IGF2	3481	insulin-like growth factor 2	receptor activator activity	Molecular function	-
PSEN2	5664	presenilin 2	negative regulation of protein binding	Biological process	-
DMRT1	1761	doublesex and mab-3 related transcription factor 1	positive regulation of mitotic nuclear division	Biological process	-
SMYD2	56950	SET and MYND domain containing 2	chromatin organization	Biological process	-
MSX1	4487	msh homeobox 1	cartilage morphogenesis	Biological process	-
ADCK4	79934	aarF domain containing kinase 4	cytosol	Cellular component	-
S100A9	6280	S100 calcium binding protein A9	leukocyte migration involved in inflammatory response	Biological process	12626582
ATP11A	23250	ATPase, class VI, type 11A	magnesium ion binding	Molecular function	-
VAV2	7410	vav 2 guanine nucleotide exchange factor	regulation of gene expression	Biological process	21810271
OR2T35	403244	olfactory receptor, family 2, subfamily T, member 35	sensory perception of smell	Biological process	-
AQP1	358	aquaporin 1 (Colton blood group)	water channel activity	Molecular function	19424603
CST1	1469	cystatin SN	protein binding	Molecular function	25416956
SRSF5	6430	serine/arginine-rich splicing factor 5	protein binding	Molecular function	12762840
SPG11	80208	spastic paraplegia 11 (autosomal recessive)	extracellular exosome	Cellular component	23376485
VANGL2	57216	VANGL planar cell polarity protein 2	somatic stem cell division	Biological process	-
SPATA24	202051	spermatogenesis associated 24	spermatogenesis	Biological process	-
AQP9	366	aquaporin 9	water channel activity	Molecular function	9733774
CERS6	253782	ceramide synthase 6	ceramide biosynthetic process	Biological process	-
WSB1	26118	WD repeat and SOCS box containing 1	protein ubiquitination	Biological process	-
CD33	945	CD33 molecule	signal transduction	Biological process	10611343
CCM2	83605	cerebral cavernous malformation 2	inner ear development	Biological process	-
OR5F1	338674	olfactory receptor, family 5, subfamily F, member 1	sensory perception of smell	Biological process	9787077
TLR2	7097	toll-like receptor 2	cellular response to bacterial lipopeptide	Biological process	15356140
PRKCE	5581	protein kinase C, epsilon	enzyme activator activity	Molecular function	18556656
LPPR2	64748	lipid phosphate phosphatase-related protein type 2	integral component of membrane	Cellular component	-
SPTBN1	6711	spectrin, beta, non-erythrocytic 1	axolemma	Cellular component	-
UMPS	7372	uridine monophosphate synthetase	'de novo' pyrimidine nucleobase biosynthetic process	Biological process	-
MTHFD1L	25902	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like	cytosol	Cellular component	-
SLC2A11	66035	solute carrier family 2 (facilitated glucose transporter), member 11	glucose transmembrane transporter activity	Molecular function	-
CASP8	841	caspase 8, apoptosis-related cysteine peptidase	death receptor binding	Molecular function	-
RAPSN	5913	receptor-associated protein of the synapse	centrosome	Cellular component	-
RPS15A	6210	ribosomal protein S15a	translational termination	Biological process	-
RBM15	64783	RNA binding motif protein 15	protein binding	Molecular function	16129689
SETX	23064	senataxin	circadian rhythm	Biological process	-
HERC5	51191	HECT and RLD domain containing E3 ubiquitin protein ligase 5	ligase activity	Molecular function	-
TUBA1A	7846	tubulin, alpha 1a	cytoplasmic microtubule	Cellular component	-
ZNF486	90649	zinc finger protein 486	biological_process	Biological process	-
ITGB1BP1	9270	integrin beta 1 binding protein 1	integrin binding	Molecular function	12473654
PRMT6	55170	protein arginine methyltransferase 6	nucleus	Cellular component	11724789
PARP1	142	poly (ADP-ribose) polymerase 1	signal transduction involved in regulation of gene expression	Biological process	-
TEK	7010	TEK tyrosine kinase, endothelial	regulation of endothelial cell apoptotic process	Biological process	18425120
UQCRC2	7385	ubiquinol-cytochrome c reductase core protein II	mitochondrial inner membrane	Cellular component	-
ASB10	136371	ankyrin repeat and SOCS box containing 10	protein ubiquitination	Biological process	-
IL27	246778	interleukin 27	innate immune response	Biological process	-
CSPG4	1464	chondroitin sulfate proteoglycan 4	carbohydrate metabolic process	Biological process	-
RELB	5971	v-rel avian reticuloendotheliosis viral oncogene homolog B	nucleoplasm	Cellular component	-
SIRPB1	10326	signal-regulatory protein beta 1	innate immune response	Biological process	-
PSMC1	5700	proteasome (prosome, macropain) 26S subunit, ATPase, 1	ER-associated ubiquitin-dependent protein catabolic process	Biological process	-
HIST1H4I	8294	histone cluster 1, H4i	protein heterodimerization activity	Molecular function	-
CYBA	1535	cytochrome b-245, alpha polypeptide	regulation of release of sequestered calcium ion into cytosol	Biological process	-
TSPYL2	64061	TSPY-like 2	cytoplasm	Cellular component	-
PTCH1	5727	patched 1	cyclin binding	Molecular function	11331587
PRDM5	11107	PR domain containing 5	metal ion binding	Molecular function	-
PDC	5132	phosducin	cytosol	Cellular component	-
GPER1	2852	G protein-coupled estrogen receptor 1	positive regulation of release of sequestered calcium ion into cytosol	Biological process	15705806
ARIH1	25820	ariadne RBR E3 ubiquitin protein ligase 1	ligase activity	Molecular function	-
FER	2241	fer (fps/fes related) tyrosine kinase	nucleus	Cellular component	19147545
SPOCK2	9806	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2	glycosaminoglycan binding	Molecular function	-
MYO9B	4650	myosin IXB	establishment of cell polarity	Biological process	-
GHRHR	2692	growth hormone releasing hormone receptor	growth hormone-releasing hormone receptor activity	Molecular function	7680413
SULF1	23213	sulfatase 1	bone development	Biological process	-
SH3YL1	26751	SH3 and SYLF domain containing 1	phosphatase binding	Molecular function	21624956
TNFRSF19	55504	tumor necrosis factor receptor superfamily, member 19	tumor necrosis factor-mediated signaling pathway	Biological process	10809768
CHODL	140578	chondrolectin	cytoplasm	Cellular component	22042635
UBE2D1	7321	ubiquitin-conjugating enzyme E2D 1	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
ICAM3	3385	intercellular adhesion molecule 3	extracellular matrix organization	Biological process	-
POU3F2	5454	POU class 3 homeobox 2	protein binding	Molecular function	11029584
EPHA2	1969	EPH receptor A2	leading edge membrane	Cellular component	19573808
RSPH9	221421	radial spoke head 9 homolog (Chlamydomonas)	cytoskeleton	Cellular component	-
FOS	2353	FBJ murine osteosarcoma viral oncogene homolog	positive regulation of osteoclast differentiation	Biological process	-
VTI1A	143187	vesicle transport through interaction with t-SNAREs 1A	SNAP receptor activity	Molecular function	15215310
C19orf18	147685	chromosome 19 open reading frame 18	extracellular exosome	Cellular component	19056867
LRP2	4036	low density lipoprotein receptor-related protein 2	calcium ion binding	Molecular function	-
MIXL1	83881	Mix paired-like homeobox	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
GJA5	2702	gap junction protein, alpha 5, 40kDa	intercalated disc	Cellular component	23348765
CBX1	10951	chromobox homolog 1	histone methyltransferase binding	Molecular function	19486527
PXT1	222659	peroxisomal, testis specific 1	molecular_function	Molecular function	-
APOC3	345	apolipoprotein C-III	cellular response to glucose stimulus	Biological process	-
RBBP7	5931	retinoblastoma binding protein 7	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
NMNAT3	349565	nicotinamide nucleotide adenylyltransferase 3	cytosol	Cellular component	-
CD80	941	CD80 molecule	positive regulation of peptidyl-tyrosine phosphorylation	Biological process	9915850
BIN3	55909	bridging integrator 3	cytoskeletal adaptor activity	Molecular function	11274158
LITAF	9516	lipopolysaccharide-induced TNF factor	positive regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	12761501
MRAS	22808	muscle RAS oncogene homolog	muscle organ development	Biological process	9395237
N4BP1	9683	NEDD4 binding protein 1	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
SPECC1L	23384	sperm antigen with calponin homology and coiled-coil domains 1-like	filamentous actin	Cellular component	-
BARHL2	343472	BarH-like homeobox 2	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
TSSK4	283629	testis-specific serine kinase 4	positive regulation of CREB transcription factor activity	Biological process	15964553
PDF	64146	peptide deformylase (mitochondrial)	mitochondrion	Cellular component	15489958
MRPL23	6150	mitochondrial ribosomal protein L23	mitochondrion	Cellular component	-
P3H1	64175	prolyl 3-hydroxylase 1	endoplasmic reticulum	Cellular component	19846465
LPIN3	64900	lipin 3	phosphatidylcholine biosynthetic process	Biological process	-
NADSYN1	55191	NAD synthetase 1	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	Molecular function	-
EAF2	55840	ELL associated factor 2	nuclear speck	Cellular component	-
AKAP9	10142	A kinase (PRKA) anchor protein 9	signal transduction	Biological process	-
ESRRA	2101	estrogen-related receptor alpha	nucleolus	Cellular component	-
IFI6	2537	interferon, alpha-inducible protein 6	integral component of membrane	Cellular component	-
CYB561	1534	cytochrome b561	transmembrane transport	Biological process	7559396
NEK2	4751	NIMA-related kinase 2	mitotic spindle assembly	Biological process	-
AKT1	207	v-akt murine thymoma viral oncogene homolog 1	negative regulation of protein kinase activity	Biological process	-
ACTR3B	57180	ARP3 actin-related protein 3 homolog B (yeast)	actin binding	Molecular function	-
MAGEL2	54551	melanoma antigen family L2	protein K63-linked ubiquitination	Biological process	23452853
TINF2	26277	TERF1 (TRF1)-interacting nuclear factor 2	chromosome, telomeric region	Cellular component	10581025
SPHK2	56848	sphingosine kinase 2	cell proliferation	Biological process	10751414
CKAP2	26586	cytoskeleton associated protein 2	centrosome	Cellular component	21399614
FOXN4	121643	forkhead box N4	enhancer sequence-specific DNA binding	Molecular function	-
UBB	7314	ubiquitin B	female meiosis I	Biological process	-
KMO	8564	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	secondary metabolite biosynthetic process	Biological process	-
ABCB6	10058	ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)	heme-transporting ATPase activity	Molecular function	17006453
UBE2QL1	134111	ubiquitin-conjugating enzyme E2Q family-like 1	protein binding	Molecular function	24000165
TCF7L2	6934	transcription factor 7-like 2 (T-cell specific, HMG-box)	transcription, DNA-templated	Biological process	-
MKI67	4288	marker of proliferation Ki-67	cytoplasm	Cellular component	-
NMUR2	56923	neuromedin U receptor 2	arachidonic acid secretion	Biological process	10887190
ORM2	5005	orosomucoid 2	transport	Biological process	-
PSMD12	5718	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	protein polyubiquitination	Biological process	-
GPI	2821	glucose-6-phosphate isomerase	gluconeogenesis	Biological process	-
HGF	3082	hepatocyte growth factor (hepapoietin A; scatter factor)	positive chemotaxis	Biological process	21245381
LAT	27040	linker for activation of T cells	plasma membrane	Cellular component	-
NR2C2	7182	nuclear receptor subfamily 2, group C, member 2	meiotic cell cycle	Biological process	-
PAIP2	51247	poly(A) binding protein interacting protein 2	memory	Biological process	-
BUB1B	701	BUB1 mitotic checkpoint serine/threonine kinase B	condensed nuclear chromosome kinetochore	Cellular component	-
LBX1	10660	ladybird homeobox 1	negative regulation of neuron differentiation	Biological process	-
OSBPL1A	114876	oxysterol binding protein-like 1A	cholesterol binding	Molecular function	17428193
HRG	3273	histidine-rich glycoprotein	platelet degranulation	Biological process	-
KHDRBS3	10656	KH domain containing, RNA binding, signal transduction associated 3	regulation of transcription, DNA-templated	Biological process	-
TRIT1	54802	tRNA isopentenyltransferase 1	cellular_component	Cellular component	-
ZFP42	132625	ZFP42 zinc finger protein	meiotic nuclear division	Biological process	18281244
AMH	268	anti-Mullerian hormone	positive regulation of NF-kappaB transcription factor activity	Biological process	-
PANK1	53354	pantothenate kinase 1	vitamin metabolic process	Biological process	-
ADAM17	6868	ADAM metallopeptidase domain 17	proteolysis	Biological process	24227843
SLC30A8	169026	solute carrier family 30 (zinc transporter), member 8	protein homodimerization activity	Molecular function	-
BCL2	596	B-cell CLL/lymphoma 2	protein phosphatase 2A binding	Molecular function	-
SLC51B	123264	solute carrier family 51, beta subunit	positive regulation of protein targeting to membrane	Biological process	-
CREB1	1385	cAMP responsive element binding protein 1	stress-activated MAPK cascade	Biological process	-
BSN	8927	bassoon presynaptic cytomatrix protein	metal ion binding	Molecular function	-
ZNF773	374928	zinc finger protein 773	nucleus	Cellular component	-
KLF4	9314	Kruppel-like factor 4 (gut)	stem cell maintenance	Biological process	-
AANAT	15	aralkylamine N-acetyltransferase	perinuclear region of cytoplasm	Cellular component	11313340
GCH1	2643	GTP cyclohydrolase 1	protein homodimerization activity	Molecular function	1669853
ELK1	2002	ELK1, member of ETS oncogene family	double-stranded DNA binding	Molecular function	-
FAM110C	642273	family with sequence similarity 110, member C	microtubule organizing center	Cellular component	-
DOCK2	1794	dedicator of cytokinesis 2	viral process	Biological process	-
CNR1	1268	cannabinoid receptor 1 (brain)	regulation of feeding behavior	Biological process	-
NF1	4763	neurofibromin 1	pigmentation	Biological process	-
POU5F2	134187	POU domain class 5, transcription factor 2	regulation of transcription, DNA-templated	Biological process	-
UGT1A4	54657	UDP glucuronosyltransferase 1 family, polypeptide A4	endoplasmic reticulum	Cellular component	20610558
NCAM1	4684	neural cell adhesion molecule 1	cell adhesion	Biological process	-
TFAP2A	7020	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	RNA polymerase II transcription coactivator activity	Molecular function	-
RNF13	11342	ring finger protein 13	Golgi membrane	Cellular component	-
TBC1D14	57533	TBC1 domain family, member 14	autophagosome	Cellular component	22613832
FAM20C	56975	family with sequence similarity 20, member C	extracellular exosome	Cellular component	19056867
CHMP7	91782	charged multivesicular body protein 7	ESCRT III complex	Cellular component	16856878
SGK1	6446	serum/glucocorticoid regulated kinase 1	regulation of blood pressure	Biological process	16460280
YOD1	55432	YOD1 deubiquitinase	protein K63-linked deubiquitination	Biological process	19818707
AGPAT1	10554	1-acylglycerol-3-phosphate O-acyltransferase 1	cellular lipid metabolic process	Biological process	-
GPRC5B	51704	G protein-coupled receptor, class C, group 5, member B	positive regulation of protein tyrosine kinase activity	Biological process	-
GFRA1	2674	GDNF family receptor alpha 1	plasma membrane	Cellular component	-
SYTL1	84958	synaptotagmin-like 1	calcium ion binding	Molecular function	-
FOXC1	2296	forkhead box C1	Notch signaling pathway	Biological process	-
FIGNL1	63979	fidgetin-like 1	regulation of double-strand break repair via homologous recombination	Biological process	23754376
SH3BGRL3	83442	SH3 domain binding glutamate-rich protein like 3	regulation of actin filament depolymerization	Biological process	24841563
LRP1	4035	low density lipoprotein receptor-related protein 1	protein binding	Molecular function	17326667
GSTP1	2950	glutathione S-transferase pi 1	negative regulation of nitric-oxide synthase biosynthetic process	Biological process	18962899
MCM5	4174	minichromosome maintenance complex component 5	membrane	Cellular component	19946888
CTSC	1075	cathepsin C	Golgi apparatus	Cellular component	-
TPR	7175	translocated promoter region, nuclear basket protein	negative regulation of translational initiation	Biological process	21613532
VEGFA	7422	vascular endothelial growth factor A	lactation	Biological process	-
FOS	2353	FBJ murine osteosarcoma viral oncogene homolog	transcription from RNA polymerase II promoter	Biological process	-
PSEN2	5664	presenilin 2	ciliary basal body	Cellular component	-
OSGEP	55644	O-sialoglycoprotein endopeptidase	cytoplasm	Cellular component	-
APOA5	116519	apolipoprotein A-V	enzyme binding	Molecular function	15178420
MAEL	84944	maelstrom spermatogenic transposon silencer	regulation of organ growth	Biological process	-
NSFL1C	55968	NSFL1 (p97) cofactor (p47)	cytosol	Cellular component	-
RIPK1	8737	receptor (TNFRSF)-interacting serine-threonine kinase 1	death-inducing signaling complex	Cellular component	11101870
TMEM123	114908	transmembrane protein 123	protein binding	Molecular function	25416956
PABPC3	5042	poly(A) binding protein, cytoplasmic 3	extracellular exosome	Cellular component	23533145
IFNL1	282618	interferon, lambda 1	JAK-STAT cascade	Biological process	-
ARPC2	10109	actin related protein 2/3 complex, subunit 2, 34kDa	Arp2/3 protein complex	Cellular component	11741539
GP6	51206	glycoprotein VI (platelet)	extracellular exosome	Cellular component	23376485
B4GALT1	2683	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	alpha-tubulin binding	Molecular function	7744867
WNT3A	89780	wingless-type MMTV integration site family, member 3A	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	-
MICALL1	85377	MICAL-like 1	membrane tubulation	Biological process	23596323
CA10	56934	carbonic anhydrase X	molecular_function	Molecular function	-
PDX1	3651	pancreatic and duodenal homeobox 1	sequence-specific DNA binding transcription factor activity	Molecular function	17941991
EXT2	2132	exostosin glycosyltransferase 2	heparan sulfate N-acetylglucosaminyltransferase activity	Molecular function	12907669
GABRG2	2566	gamma-aminobutyric acid (GABA) A receptor, gamma 2	chloride channel complex	Cellular component	-
GTF2H2C_2	730394	GTF2H2 family member C, copy 2	zinc ion binding	Molecular function	-
TMEM67	91147	transmembrane protein 67	unfolded protein binding	Molecular function	19815549
HAUS7	55559	HAUS augmin-like complex, subunit 7	mitotic nuclear division	Biological process	-
APOBEC3H	164668	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H	negative regulation of viral process	Biological process	18827027
SRPRB	58477	signal recognition particle receptor, B subunit	cellular protein metabolic process	Biological process	-
SLC4A11	83959	solute carrier family 4, sodium borate transporter, member 11	basolateral plasma membrane	Cellular component	15525507
NUP43	348995	nucleoporin 43kDa	small molecule metabolic process	Biological process	-
DHRS9	10170	dehydrogenase/reductase (SDR family) member 9	epithelial cell differentiation	Biological process	11304534
ALKBH5	54890	AlkB family member 5, RNA demethylase	mRNA export from nucleus	Biological process	23177736
KDM2A	22992	lysine (K)-specific demethylase 2A	unmethylated CpG binding	Molecular function	-
EHD1	10938	EH-domain containing 1	endocytosis	Biological process	20801876
KLLN	100144748	killin, p53-regulated DNA replication inhibitor	DNA binding	Molecular function	-
CCNF	899	cyclin F	placenta development	Biological process	-
CBX5	23468	chromobox homolog 5	nucleus	Cellular component	-
KCNH1	3756	potassium channel, voltage gated eag related subfamily H, member 1	regulation of cell proliferation	Biological process	23881642
MYL12A	10627	myosin, light chain 12A, regulatory, non-sarcomeric	muscle contraction	Biological process	-
FOXO3	2309	forkhead box O3	transcription from RNA polymerase II promoter	Biological process	-
ITGA8	8516	integrin, alpha 8	mesodermal cell differentiation	Biological process	23154389
CXXC1	30827	CXXC finger protein 1	protein binding	Molecular function	17998332
TAF6	6878	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa	gene expression	Biological process	-
UBXN7	26043	UBX domain protein 7	nucleoplasm	Cellular component	-
EDNRB	1910	endothelin receptor type B	nuclear membrane	Cellular component	-
PURB	5814	purine-rich element binding protein B	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
SNX4	8723	sorting nexin 4	cytoplasm	Cellular component	11279102
CDK5	1020	cyclin-dependent kinase 5	skeletal muscle tissue development	Biological process	-
TRIM23	373	tripartite motif containing 23	protein ubiquitination	Biological process	-
NRP2	8828	neuropilin 2	extracellular region	Cellular component	-
DAB2IP	153090	DAB2 interacting protein	positive regulation of cell cycle arrest	Biological process	19903888
TNKS1BP1	85456	tankyrase 1 binding protein 1, 182kDa	cytoskeleton	Cellular component	-
TP53I3	9540	tumor protein p53 inducible protein 3	NADPH:quinone reductase activity	Molecular function	19349281
ACTC1	70	actin, alpha, cardiac muscle 1	membrane	Cellular component	19946888
PCDHA4	56144	protocadherin alpha 4	protein binding	Molecular function	25416956
SIGLEC16	400709	sialic acid binding Ig-like lectin 16 (gene/pseudogene)	integral component of membrane	Cellular component	-
RPH3AL	9501	rabphilin 3A-like (without C2 domains)	regulation of calcium ion-dependent exocytosis	Biological process	-
TIMP1	7076	TIMP metallopeptidase inhibitor 1	response to cytokine	Biological process	-
CUL7	9820	cullin 7	IRE1-mediated unfolded protein response	Biological process	-
CCR2	729230	chemokine (C-C motif) receptor 2	dendritic cell chemotaxis	Biological process	16621978
CBS	875	cystathionine-beta-synthase	L-serine catabolic process	Biological process	18776696
TEK	7010	TEK tyrosine kinase, endothelial	negative regulation of inflammatory response	Biological process	18366015
ATP2A1	487	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	blood coagulation	Biological process	-
HOMER1	9456	homer scaffolding protein 1	plasma membrane	Cellular component	-
RXRG	6258	retinoid X receptor, gamma	gene expression	Biological process	-
LIG3	3980	ligase III, DNA, ATP-dependent	mitochondrial DNA repair	Biological process	21390132
NRIP3	56675	nuclear receptor interacting protein 3	proteolysis	Biological process	-
IRS4	8471	insulin receptor substrate 4	protein binding	Molecular function	11316748
CLP1	10978	cleavage and polyadenylation factor I subunit 1	phosphorylation	Biological process	-
MRGBP	55257	MRG/MORF4L binding protein	transcription, DNA-templated	Biological process	-
HLA-DRB1	3123	major histocompatibility complex, class II, DR beta 1	plasma membrane	Cellular component	-
EXT2	2132	exostosin glycosyltransferase 2	mesoderm formation	Biological process	-
TGFBR3	7049	transforming growth factor, beta receptor III	response to hypoxia	Biological process	-
ACVR1C	130399	activin A receptor, type IC	lipid storage	Biological process	-
BACE1	23621	beta-site APP-cleaving enzyme 1	beta-amyloid binding	Molecular function	16407538
PAIP2	51247	poly(A) binding protein interacting protein 2	protein binding	Molecular function	11172725
ATP1A2	477	ATPase, Na+/K+ transporting, alpha 2 polypeptide	ion transmembrane transport	Biological process	-
SCN5A	6331	sodium channel, voltage gated, type V alpha subunit	regulation of cardiac muscle cell contraction	Biological process	22529811
RAB2A	5862	RAB2A, member RAS oncogene family	lysosomal membrane	Cellular component	17897319
TIAL1	7073	TIA1 cytotoxic granule-associated RNA binding protein-like 1	nucleotide binding	Molecular function	-
SPATA31A5	727905	SPATA31 subfamily A, member 5	cell differentiation	Biological process	-
ZBTB45	84878	zinc finger and BTB domain containing 45	metal ion binding	Molecular function	-
STX8	9482	syntaxin 8	intracellular protein transport	Biological process	-
HSD3B1	3283	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1	estrogen biosynthetic process	Biological process	1944309
GATA2	2624	GATA binding protein 2	transcription, DNA-templated	Biological process	16153155
EREG	2069	epiregulin	innate immune response	Biological process	-
ATG9A	79065	autophagy related 9A	late endosome membrane	Cellular component	-
MYL4	4635	myosin, light chain 4, alkali; atrial, embryonic	actin monomer binding	Molecular function	9180271
CSNK2A1	1457	casein kinase 2, alpha 1 polypeptide	protein N-terminus binding	Molecular function	11972058
PDE6H	5149	phosphodiesterase 6H, cGMP-specific, cone, gamma	positive regulation of G-protein coupled receptor protein signaling pathway	Biological process	-
CLDN24	100132463	claudin 24	plasma membrane	Cellular component	-
TRIM5	85363	tripartite motif containing 5	cytosol	Cellular component	-
FASN	2194	fatty acid synthase	[acyl-carrier-protein] S-acetyltransferase activity	Molecular function	-
SHC1	6464	SHC (Src homology 2 domain containing) transforming protein 1	regulation of epidermal growth factor-activated receptor activity	Biological process	1623525
EFNA1	1942	ephrin-A1	receptor binding	Molecular function	8660976
ACSS2	55902	acyl-CoA synthetase short-chain family member 2	xenobiotic metabolic process	Biological process	-
QPRT	23475	quinolinate phosphoribosyltransferase	cytosol	Cellular component	-
SOX15	6665	SRY (sex determining region Y)-box 15	cytoplasm	Cellular component	-
FGF2	2247	fibroblast growth factor 2 (basic)	cytokine activity	Molecular function	18059339
FAF1	11124	Fas (TNFRSF6) associated factor 1	regulation of protein catabolic process	Biological process	15743842
CCT4	10575	chaperonin containing TCP1, subunit 4 (delta)	chaperonin-containing T-complex	Cellular component	23011926
POLR3K	51728	polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa	DNA-directed RNA polymerase activity	Molecular function	9869639
KCNH7	90134	potassium channel, voltage gated eag related subfamily H, member 7	inward rectifier potassium channel activity	Molecular function	-
SP100	6672	SP100 nuclear antigen	PML body	Cellular component	11313457
MEF2C	4208	myocyte enhancer factor 2C	B cell proliferation	Biological process	-
MTCP1	4515	mature T-cell proliferation 1	mitochondrion	Cellular component	-
PSMD6	9861	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	proteasome accessory complex	Cellular component	-
C8A	731	complement component 8, alpha polypeptide	complement activation	Biological process	12413696
IL21	59067	interleukin 21	positive regulation of interleukin-17 production	Biological process	16482511
SP100	6672	SP100 nuclear antigen	negative regulation of protein export from nucleus	Biological process	17245429
EMILIN2	84034	elastin microfibril interfacer 2	extracellular region	Cellular component	11278945
SOX15	6665	SRY (sex determining region Y)-box 15	skeletal muscle tissue regeneration	Biological process	-
NAIF1	203245	nuclear apoptosis inducing factor 1	negative regulation of cell growth	Biological process	16378748
COL1A1	1277	collagen, type I, alpha 1	collagen biosynthetic process	Biological process	15095409
CAPZA2	830	capping protein (actin filament) muscle Z-line, alpha 2	movement of cell or subcellular component	Biological process	9331217
STOM	2040	stomatin	extracellular exosome	Cellular component	19056867
EMP2	2013	epithelial membrane protein 2	T cell mediated cytotoxicity	Biological process	-
MESP1	55897	mesoderm posterior basic helix-loop-helix transcription factor 1	Notch signaling pathway	Biological process	-
HIST1H3H	8357	histone cluster 1, H3h	extracellular exosome	Cellular component	20458337
ANTXR1	84168	anthrax toxin receptor 1	reproductive process	Biological process	-
BRICD5	283870	BRICHOS domain containing 5	protein binding	Molecular function	25416956
EIF2AK1	27102	eukaryotic translation initiation factor 2-alpha kinase 1	protoporphyrinogen IX metabolic process	Biological process	-
AGO2	27161	argonaute RISC catalytic component 2	double-stranded RNA binding	Molecular function	19966796
LHPP	64077	phospholysine phosphohistidine inorganic pyrophosphate phosphatase	cytoplasm	Cellular component	-
DCX	1641	doublecortin	central nervous system development	Biological process	9489699
DGKA	1606	diacylglycerol kinase, alpha 80kDa	membrane	Cellular component	19946888
RNF180	285671	ring finger protein 180	ligase activity	Molecular function	-
ALAS2	212	5'-aminolevulinate synthase 2	small molecule metabolic process	Biological process	-
AGO1	26523	argonaute RISC catalytic component 1	micro-ribonucleoprotein complex	Cellular component	17932509
TNF	7124	tumor necrosis factor	positive regulation of transcription from RNA polymerase II promoter	Biological process	16803872
ACTR3	10096	ARP3 actin-related protein 3 homolog (yeast)	actin filament binding	Molecular function	11741539
MLLT4	4301	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	cell-cell junction	Cellular component	10856295
SULT2A1	6822	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	bile-salt sulfotransferase activity	Molecular function	-
TIRAP	114609	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	toll-like receptor TLR6:TLR2 signaling pathway	Biological process	-
INHBA	3624	inhibin, beta A	hematopoietic progenitor cell differentiation	Biological process	15451575
PDXP	57026	pyridoxal (pyridoxine, vitamin B6) phosphatase	contractile ring	Cellular component	15580268
ZNF571	51276	zinc finger protein 571	regulation of transcription, DNA-templated	Biological process	-
CD3E	916	CD3e molecule, epsilon (CD3-TCR complex)	positive regulation of alpha-beta T cell proliferation	Biological process	-
STX5	6811	syntaxin 5	endoplasmic reticulum-Golgi intermediate compartment membrane	Cellular component	-
EZR	7430	ezrin	sphingosine-1-phosphate signaling pathway	Biological process	23106337
JCHAIN	3512	joining chain of multimeric IgA and IgM	positive regulation of protein oligomerization	Biological process	17237408
IL1R1	3554	interleukin 1 receptor, type I	response to interleukin-1	Biological process	10383454
CCBL1	883	cysteine conjugate-beta lyase, cytoplasmic	tryptophan catabolic process	Biological process	-
GTF2IRD1	9569	GTF2I repeat domain containing 1	cytoplasm	Cellular component	-
NLGN4X	57502	neuroligin 4, X-linked	carboxylic ester hydrolase activity	Molecular function	-
SLC5A11	115584	solute carrier family 5 (sodium/inositol cotransporter), member 11	integral component of membrane	Cellular component	-
IL17F	112744	interleukin 17F	proteoglycan metabolic process	Biological process	11574464
CD46	4179	CD46 molecule, complement regulatory protein	integral component of plasma membrane	Cellular component	1711570
PRDX5	25824	peroxiredoxin 5	negative regulation of transcription from RNA polymerase III promoter	Biological process	10095767
RGS4	5999	regulator of G-protein signaling 4	positive regulation of GTPase activity	Biological process	-
PCSK9	255738	proprotein convertase subtilisin/kexin type 9	apoptotic process	Biological process	-
TYROBP	7305	TYRO protein tyrosine kinase binding protein	innate immune response	Biological process	-
KCNH2	3757	potassium channel, voltage gated eag related subfamily H, member 2	C3HC4-type RING finger domain binding	Molecular function	25281747
NUP153	9972	nucleoporin 153kDa	mitotic cell cycle	Biological process	-
PRUNE2	158471	prune homolog 2 (Drosophila)	metabolic process	Biological process	-
SCFD2	152579	sec1 family domain containing 2	vesicle docking involved in exocytosis	Biological process	-
CMYA5	202333	cardiomyopathy associated 5	perinuclear region of cytoplasm	Cellular component	-
NKTR	4820	natural killer cell triggering receptor	cyclosporin A binding	Molecular function	8421688
LDHD	197257	lactate dehydrogenase D	mitochondrial inner membrane	Cellular component	-
SLC11A2	4891	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2	brush border	Cellular component	-
HES5	388585	hes family bHLH transcription factor 5	glial cell fate commitment	Biological process	-
RHOT1	55288	ras homolog family member T1	membrane	Cellular component	19946888
TRIAP1	51499	TP53 regulated inhibitor of apoptosis 1	protein complex	Cellular component	23931759
PPP5C	5536	protein phosphatase 5, catalytic subunit	transcription, DNA-templated	Biological process	7925273
ENPP2	5168	ectonucleotide pyrophosphatase/phosphodiesterase 2	receptor-mediated endocytosis	Biological process	-
PLOD3	8985	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3	procollagen glucosyltransferase activity	Molecular function	-
RPL18	6141	ribosomal protein L18	cytoplasm	Cellular component	-
ZFAND5	7763	zinc finger, AN1-type domain 5	protein binding	Molecular function	16424905
CTNNA1	1495	catenin (cadherin-associated protein), alpha 1, 102kDa	acrosomal vesicle	Cellular component	-
IFITM1	8519	interferon induced transmembrane protein 1	negative regulation of viral entry into host cell	Biological process	21253575
GABRA3	2556	gamma-aminobutyric acid (GABA) A receptor, alpha 3	postsynaptic membrane	Cellular component	-
TRPC4	7223	transient receptor potential cation channel, subfamily C, member 4	cell surface	Cellular component	19996314
TGFBR2	7048	transforming growth factor, beta receptor II (70/80kDa)	positive regulation of B cell tolerance induction	Biological process	-
DAPK3	1613	death-associated protein kinase 3	protein serine/threonine kinase activity	Molecular function	16756490
PDZD4	57595	PDZ domain containing 4	ubiquitin protein ligase activity	Molecular function	-
GSTM1	2944	glutathione S-transferase mu 1	glutathione metabolic process	Biological process	8373352
SOCS5	9655	suppressor of cytokine signaling 5	cytoplasm	Cellular component	-
SENP1	29843	SUMO1/sentrin specific peptidase 1	focal adhesion	Cellular component	-
UTRN	7402	utrophin	sarcolemma	Cellular component	-
PPM1E	22843	protein phosphatase, Mg2+/Mn2+ dependent, 1E	mitochondrion	Cellular component	-
APOL1	8542	apolipoprotein L, 1	innate immune response	Biological process	17192540
TCF7L2	6934	transcription factor 7-like 2 (T-cell specific, HMG-box)	embryonic genitalia morphogenesis	Biological process	-
MED1	5469	mediator complex subunit 1	mediator complex	Cellular component	17641689
AXL	558	AXL receptor tyrosine kinase	protein binding	Molecular function	16362042
BRAF	673	B-Raf proto-oncogene, serine/threonine kinase	protein binding	Molecular function	12620389
RARRES2	5919	retinoic acid receptor responder (tazarotene induced) 2	inflammatory response	Biological process	-
TPP2	7174	tripeptidyl peptidase II	proteolysis	Biological process	-
SOX4	6659	SRY (sex determining region Y)-box 4	DNA damage response, detection of DNA damage	Biological process	19234109
RXRB	6257	retinoid X receptor, beta	protein binding	Molecular function	16189514
FAM3C	10447	family with sequence similarity 3, member C	Golgi apparatus	Cellular component	-
BCL2	596	B-cell CLL/lymphoma 2	peptidyl-serine phosphorylation	Biological process	-
GEMIN5	25929	gem (nuclear organelle) associated protein 5	mRNA splicing, via spliceosome	Biological process	11714716
ORMDL1	94101	ORMDL sphingolipid biosynthesis regulator 1	negative regulation of sphingolipid biosynthetic process	Biological process	-
ARFGEF3	57221	ARFGEF family member 3	integral component of membrane	Cellular component	-
MRPS34	65993	mitochondrial ribosomal protein S34	mitochondrial translational elongation	Biological process	-
SGK3	23678	serum/glucocorticoid regulated kinase family, member 3	early endosome	Cellular component	-
PCM1	5108	pericentriolar material 1	ciliary basal body	Cellular component	-
PRKAG1	5571	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	nucleus	Cellular component	-
GTF3A	2971	general transcription factor IIIA	gene expression	Biological process	-
NNT	23530	nicotinamide nucleotide transhydrogenase	NAD(P)+ transhydrogenase (B-specific) activity	Molecular function	9524818
TCTN1	79600	tectonic family member 1	extracellular space	Cellular component	-
CLPP	8192	caseinolytic mitochondrial matrix peptidase proteolytic subunit	peptidase activity	Molecular function	8543061
CYP2C9	1559	cytochrome P450, family 2, subfamily C, polypeptide 9	(R)-limonene 6-monooxygenase activity	Molecular function	-
VAV3	10451	vav 3 guanine nucleotide exchange factor	Fc-epsilon receptor signaling pathway	Biological process	-
TIPARP	25976	TCDD-inducible poly(ADP-ribose) polymerase	platelet-derived growth factor receptor signaling pathway	Biological process	-
SIX4	51804	SIX homeobox 4	skeletal muscle tissue development	Biological process	-
LGR6	59352	leucine-rich repeat containing G protein-coupled receptor 6	protein binding	Molecular function	21727895
FBXL21	26223	F-box and leucine-rich repeat protein 21 (gene/pseudogene)	nucleus	Cellular component	-
MGST2	4258	microsomal glutathione S-transferase 2	integral component of membrane	Cellular component	-
CLIP1	6249	CAP-GLY domain containing linker protein 1	microtubule cytoskeleton	Cellular component	17889670
STK4	6789	serine/threonine kinase 4	protein serine/threonine kinase activity	Molecular function	11805089
MRPL18	29074	mitochondrial ribosomal protein L18	translation	Biological process	11543634
TAC3	6866	tachykinin 3	neuropeptide signaling pathway	Biological process	-
CPM	1368	carboxypeptidase M	cell surface	Cellular component	19581412
NKX2-2	4821	NK2 homeobox 2	spinal cord motor neuron differentiation	Biological process	-
ZFP36L2	678	ZFP36 ring finger protein-like 2	hemopoiesis	Biological process	-
C9orf116	138162	chromosome 9 open reading frame 116	protein binding	Molecular function	25416956
NR1H3	10062	nuclear receptor subfamily 1, group H, member 3	receptor complex	Cellular component	18511497
AIFM1	9131	apoptosis-inducing factor, mitochondrion-associated, 1	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	Biological process	-
B3GNT4	79369	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4	glycosaminoglycan metabolic process	Biological process	-
ZNF774	342132	zinc finger protein 774	regulation of transcription, DNA-templated	Biological process	-
SEC63	11231	SEC63 homolog (S. cerevisiae)	membrane	Cellular component	22375059
FER	2241	fer (fps/fes related) tyrosine kinase	cytosol	Cellular component	-
NELFE	7936	negative elongation factor complex member E	gene expression	Biological process	-
PTK2	5747	protein tyrosine kinase 2	apical plasma membrane	Cellular component	-
HTRA1	5654	HtrA serine peptidase 1	negative regulation of defense response to virus	Biological process	-
UGT1A1	54658	UDP glucuronosyltransferase 1 family, polypeptide A1	negative regulation of transferase activity	Biological process	20610558
TRPC7	57113	transient receptor potential cation channel, subfamily C, member 7	inositol 1,4,5 trisphosphate binding	Molecular function	-
IFITM1	8519	interferon induced transmembrane protein 1	response to interferon-gamma	Biological process	21253575
PSMC4	5704	proteasome (prosome, macropain) 26S subunit, ATPase, 4	regulation of cellular amino acid metabolic process	Biological process	-
SQSTM1	8878	sequestosome 1	receptor tyrosine kinase binding	Molecular function	8650207
PODXL2	50512	podocalyxin-like 2	leukocyte tethering or rolling	Biological process	18606703
GNAT2	2780	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2	G-protein coupled receptor binding	Molecular function	-
COL3A1	1281	collagen, type III, alpha 1	negative regulation of neuron migration	Biological process	-
PRKCA	5578	protein kinase C, alpha	positive regulation of mitotic cell cycle	Biological process	10848585
BMP4	652	bone morphogenetic protein 4	activation of MAPKK activity	Biological process	17600318
MBD4	8930	methyl-CpG binding domain protein 4	satellite DNA binding	Molecular function	9774669
NKD1	85407	naked cuticle homolog 1 (Drosophila)	calcium ion binding	Molecular function	-
JMJD6	23210	jumonji domain containing 6	oxidation-reduction process	Biological process	-
TGIF1	7050	TGFB-induced factor homeobox 1	sequence-specific DNA binding transcription factor activity	Molecular function	8537382
IL33	90865	interleukin 33	positive regulation of transcription from RNA polymerase II promoter	Biological process	19841166
CNTFR	1271	ciliary neurotrophic factor receptor	positive regulation of cell proliferation	Biological process	-
MRPS16	51021	mitochondrial ribosomal protein S16	cytoplasm	Cellular component	-
IGHV2-70	28454	immunoglobulin heavy variable 2-70	receptor-mediated endocytosis	Biological process	-
HNRNPR	10236	heterogeneous nuclear ribonucleoprotein R	mRNA processing	Biological process	9421497
ECM1	1893	extracellular matrix protein 1	protein C-terminus binding	Molecular function	12604605
STK16	8576	serine/threonine kinase 16	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
SMPD4	55627	sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)	ceramide biosynthetic process	Biological process	16517606
CBS	875	cystathionine-beta-synthase	nitric oxide binding	Molecular function	24416422
EXOSC4	54512	exosome component 4	nucleus	Cellular component	17545563
IGFN1	91156	immunoglobulin-like and fibronectin type III domain containing 1	protein binding	Molecular function	25416956
CD1A	909	CD1a molecule	plasma membrane	Cellular component	-
PAFAH1B1	5048	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	lipid catabolic process	Biological process	-
CRCP	27297	CGRP receptor component	DNA-directed RNA polymerase III complex	Cellular component	-
SELE	6401	selectin E	positive regulation of receptor internalization	Biological process	9312078
PML	5371	promyelocytic leukemia	regulation of double-strand break repair	Biological process	21639834
SFTPA1	653509	surfactant protein A1	lipid transport	Biological process	2995821
RPL18A	6142	ribosomal protein L18a	SRP-dependent cotranslational protein targeting to membrane	Biological process	-
CD1D	912	CD1d molecule	cytoplasm	Cellular component	19124746
CELF4	56853	CUGBP, Elav-like family member 4	regulation of alternative mRNA splicing, via spliceosome	Biological process	11158314
EPO	2056	erythropoietin	protein binding	Molecular function	9774108
LYN	4067	LYN proto-oncogene, Src family tyrosine kinase	cytokine secretion	Biological process	-
TUBB	203068	tubulin, beta class I	extracellular exosome	Cellular component	12519789
C10orf99	387695	chromosome 10 open reading frame 99	negative regulation of cell cycle G1/S phase transition	Biological process	25351403
AP3D1	8943	adaptor-related protein complex 3, delta 1 subunit	protein localization to organelle	Biological process	-
RRAGC	64121	Ras-related GTP binding C	magnesium ion binding	Molecular function	11073942
PFN1	5216	profilin 1	negative regulation of stress fiber assembly	Biological process	23153535
BCL11B	64919	B-cell CLL/lymphoma 11B (zinc finger protein)	metal ion binding	Molecular function	-
FZD5	7855	frizzled class receptor 5	angiogenesis	Biological process	-
APBB1	322	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	negative regulation of cell growth	Biological process	-
SDAD1	55153	SDA1 domain containing 1	nucleolus	Cellular component	-
UVRAG	7405	UV radiation resistance associated	midbody	Cellular component	20643123
NEIL2	252969	nei endonuclease VIII-like 2 (E. coli)	spindle microtubule	Cellular component	-
PDX1	3651	pancreatic and duodenal homeobox 1	detection of glucose	Biological process	-
MYH4	4622	myosin, heavy chain 4, skeletal muscle	response to activity	Biological process	-
AURKA	6790	aurora kinase A	negative regulation of apoptotic process	Biological process	-
R3HCC1L	27291	R3H domain and coiled-coil containing 1-like	protein binding	Molecular function	25416956
PSTPIP1	9051	proline-serine-threonine phosphatase interacting protein 1	actin binding	Molecular function	-
EEF1A1	1915	eukaryotic translation elongation factor 1 alpha 1	ruffle membrane	Cellular component	19158340
TDG	6996	thymine-DNA glycosylase	negative regulation of chromatin binding	Biological process	-
SNTB2	6645	syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)	transport vesicle membrane	Cellular component	-
HEPHL1	341208	hephaestin-like 1	copper ion binding	Molecular function	-
AIF1	199	allograft inflammatory factor 1	negative regulation of gene expression	Biological process	-
BSG	682	basigin (Ok blood group)	response to cAMP	Biological process	-
TWIST1	7291	twist family bHLH transcription factor 1	protein domain specific binding	Molecular function	-
ZNF222	7673	zinc finger protein 222	transcription, DNA-templated	Biological process	-
DDIT4	54541	DNA-damage-inducible transcript 4	mitochondrion	Cellular component	-
SYBU	55638	syntabulin (syntaxin-interacting)	vesicle	Cellular component	15459722
KAT6A	7994	K(lysine) acetyltransferase 6A	positive regulation of transcription, DNA-templated	Biological process	11742995
ALOX12	239	arachidonate 12-lipoxygenase	aging	Biological process	-
LLGL1	3996	lethal giant larvae homolog 1 (Drosophila)	positive regulation of GTPase activity	Biological process	-
YAP1	10413	Yes-associated protein 1	embryonic heart tube morphogenesis	Biological process	-
EFTUD1	79631	elongation factor Tu GTP binding domain containing 1	ribosome binding	Molecular function	21536732
RPS6KC1	26750	ribosomal protein S6 kinase, 52kDa, polypeptide 1	intracellular membrane-bounded organelle	Cellular component	-
INSR	3643	insulin receptor	protein tyrosine kinase activity	Molecular function	7537849
PPP2R4	5524	protein phosphatase 2A activator, regulatory subunit 4	cytoplasm	Cellular component	17333320
RHBDL1	9028	rhomboid, veinlet-like 1 (Drosophila)	protein processing	Biological process	-
SIN3B	23309	SIN3 transcription regulator family member B	autosome	Cellular component	-
WDPCP	51057	WD repeat containing planar cell polarity effector	smoothened signaling pathway	Biological process	-
SIGLEC8	27181	sialic acid binding Ig-like lectin 8	transmembrane signaling receptor activity	Molecular function	10625619
ZNF34	80778	zinc finger protein 34	DNA binding	Molecular function	-
RHOJ	57381	ras homolog family member J	actin cytoskeleton organization	Biological process	10967094
SHMT1	6470	serine hydroxymethyltransferase 1 (soluble)	amino acid binding	Molecular function	-
LEP	3952	leptin	response to hypoxia	Biological process	-
IDI1	3422	isopentenyl-diphosphate delta isomerase 1	manganese ion binding	Molecular function	17250851
AR	367	androgen receptor	beta-catenin binding	Molecular function	16344550
NAP1L2	4674	nucleosome assembly protein 1-like 2	positive regulation of histone H3-K14 acetylation	Biological process	-
HDAC3	8841	histone deacetylase 3	cellular response to fluid shear stress	Biological process	25190803
UBE2NL	389898	ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)	extracellular exosome	Cellular component	23533145
MRPL21	219927	mitochondrial ribosomal protein L21	mitochondrial inner membrane	Cellular component	-
TBC1D5	9779	TBC1 domain family, member 5	endosome membrane	Cellular component	20923837
HDAC6	10013	histone deacetylase 6	inclusion body	Cellular component	16192271
SLC6A1	6529	solute carrier family 6 (neurotransmitter transporter), member 1	activation of mitophagy in response to mitochondrial depolarization	Biological process	22020285
GET4	51608	golgi to ER traffic protein 4 homolog (S. cerevisiae)	protein binding	Molecular function	21516116
CTBP1	1487	C-terminal binding protein 1	viral genome replication	Biological process	7479821
NIT2	56954	nitrilase family, member 2	glutamine metabolic process	Biological process	22674578
BAAT	570	bile acid CoA:amino acid N-acyltransferase	acyl-CoA metabolic process	Biological process	12810727
TULP3	7289	tubby like protein 3	ganglion development	Biological process	-
SATB1	6304	SATB homeobox 1	nucleus	Cellular component	18408014
PPP3R1	5534	protein phosphatase 3, regulatory subunit B, alpha	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	Biological process	-
NASP	4678	nuclear autoantigenic sperm protein (histone-binding)	cytoplasm	Cellular component	-
DSC1	1823	desmocollin 1	homophilic cell adhesion via plasma membrane adhesion molecules	Biological process	-
TWIST1	7291	twist family bHLH transcription factor 1	negative regulation of histone phosphorylation	Biological process	17690110
LY96	23643	lymphocyte antigen 96	extracellular space	Cellular component	-
CYP51A1	1595	cytochrome P450, family 51, subfamily A, polypeptide 1	sterol metabolic process	Biological process	-
STX5	6811	syntaxin 5	ER to Golgi vesicle-mediated transport	Biological process	-
NUP205	23165	nucleoporin 205kDa	viral process	Biological process	-
XRCC4	7518	X-ray repair complementing defective repair in Chinese hamster cells 4	positive regulation of fibroblast proliferation	Biological process	-
GAS2L2	246176	growth arrest-specific 2 like 2	cytoskeleton	Cellular component	-
OR2Y1	134083	olfactory receptor, family 2, subfamily Y, member 1	olfactory receptor activity	Molecular function	-
PPP1CA	5499	protein phosphatase 1, catalytic subunit, alpha isozyme	cell cycle	Biological process	-
EPC1	80314	enhancer of polycomb homolog 1 (Drosophila)	transcription, DNA-templated	Biological process	10976108
EGR1	1958	early growth response 1	DNA binding	Molecular function	12560508
CAMLG	819	calcium modulating ligand	viral process	Biological process	-
COL18A1	80781	collagen, type XVIII, alpha 1	angiogenesis	Biological process	-
NEK5	341676	NIMA-related kinase 5	ATP binding	Molecular function	-
MYL6	4637	myosin, light chain 6, alkali, smooth muscle and non-muscle	metabolic process	Biological process	2304459
CETN2	1069	centrin, EF-hand protein, 2	cytosol	Cellular component	-
LGALS1	3956	lectin, galactoside-binding, soluble, 1	protein homodimerization activity	Molecular function	-
SNCB	6620	synuclein, beta	growth cone	Cellular component	-
ZNF648	127665	zinc finger protein 648	DNA binding	Molecular function	-
ARHGAP35	2909	Rho GTPase activating protein 35	DNA binding	Molecular function	1894621
SRGN	5552	serglycin	Golgi membrane	Cellular component	-
MDM2	4193	MDM2 proto-oncogene, E3 ubiquitin protein ligase	cytoplasm	Cellular component	21726810
NUDT16	131870	nudix (nucleoside diphosphate linked moiety X)-type motif 16	nucleus	Cellular component	-
ZNF808	388558	zinc finger protein 808	transcription, DNA-templated	Biological process	-
CFTR	1080	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	water transport	Biological process	-
TMF1	7110	TATA element modulatory factor 1	defense response to bacterium	Biological process	-
HRAS	3265	Harvey rat sarcoma viral oncogene homolog	positive regulation of MAPK cascade	Biological process	9765203
CDKN1A	1026	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	protein phosphorylation	Biological process	9106657
SLC22A1	6580	solute carrier family 22 (organic cation transporter), member 1	quaternary ammonium group transmembrane transporter activity	Molecular function	-
CD38	952	CD38 molecule	nucleus	Cellular component	-
GNB1	2782	guanine nucleotide binding protein (G protein), beta polypeptide 1	protein binding	Molecular function	16782902
AMZ1	155185	archaelysin family metallopeptidase 1	proteolysis	Biological process	-
ABCA5	23461	ATP-binding cassette, sub-family A (ABC1), member 5	Golgi membrane	Cellular component	-
WFDC9	259240	WAP four-disulfide core domain 9	extracellular region	Cellular component	-
PARM1	25849	prostate androgen-regulated mucin-like protein 1	Golgi apparatus	Cellular component	18027867
EXOSC10	5394	exosome component 10	nucleus	Cellular component	-
PRKAB2	5565	protein kinase, AMP-activated, beta 2 non-catalytic subunit	transcription initiation from RNA polymerase II promoter	Biological process	-
NAT14	57106	N-acetyltransferase 14 (GCN5-related, putative)	DNA-templated transcription, initiation	Biological process	10873651
SOCS3	9021	suppressor of cytokine signaling 3	branching involved in labyrinthine layer morphogenesis	Biological process	-
HKDC1	80201	hexokinase domain containing 1	carbohydrate phosphorylation	Biological process	-
TRAPPC2	6399	trafficking protein particle complex 2	transcription factor binding	Molecular function	11134351
F7	2155	coagulation factor VII (serum prothrombin conversion accelerator)	cellular protein metabolic process	Biological process	-
KIF20B	9585	kinesin family member 20B	regulation of establishment of protein localization	Biological process	-
PARK2	5071	parkin RBR E3 ubiquitin protein ligase	regulation of protein targeting to mitochondrion	Biological process	20890124
CRP	1401	C-reactive protein, pentraxin-related	low-density lipoprotein particle binding	Molecular function	18322245
GPRC5B	51704	G protein-coupled receptor, class C, group 5, member B	extracellular exosome	Cellular component	19056867
RRAGB	10325	Ras-related GTP binding B	regulation of autophagy	Biological process	-
IL2RG	3561	interleukin 2 receptor, gamma	membrane	Cellular component	19946888
AKR7A2	8574	aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)	alditol:NADP+ 1-oxidoreductase activity	Molecular function	-
PLSCR1	5359	phospholipid scramblase 1	epidermal growth factor receptor binding	Molecular function	12009895
BMP4	652	bone morphogenetic protein 4	anterior/posterior axis specification	Biological process	-
CYP1A2	1544	cytochrome P450, family 1, subfamily A, polypeptide 2	toxin biosynthetic process	Biological process	11511187
SPOPL	339745	speckle-type POZ protein-like	Cul3-RING ubiquitin ligase complex	Cellular component	22632832
WNT3A	89780	wingless-type MMTV integration site family, member 3A	positive regulation of cell proliferation	Biological process	-
OR52L2P	79274	olfactory receptor, family 52, subfamily L, member 2 pseudogene	plasma membrane	Cellular component	-
POLR2E	5434	polymerase (RNA) II (DNA directed) polypeptide E, 25kDa	transcription-coupled nucleotide-excision repair	Biological process	-
CEBPA	1050	CCAAT/enhancer binding protein (C/EBP), alpha	organ regeneration	Biological process	-
PCBP4	57060	poly(rC) binding protein 4	RNA binding	Molecular function	10936052
MFAP5	8076	microfibrillar associated protein 5	extracellular fibril organization	Biological process	-
TRMT10A	93587	tRNA methyltransferase 10 homolog A (S. cerevisiae)	magnesium ion homeostasis	Biological process	-
SSX2IP	117178	synovial sarcoma, X breakpoint 2 interacting protein	cilium assembly	Biological process	24356449
USP43	124739	ubiquitin specific peptidase 43	ubiquitin-specific protease activity	Molecular function	-
CDHR3	222256	cadherin-related family member 3	homophilic cell adhesion via plasma membrane adhesion molecules	Biological process	-
WNT2	7472	wingless-type MMTV integration site family member 2	cardiac epithelial to mesenchymal transition	Biological process	-
FZD3	7976	frizzled class receptor 3	PDZ domain binding	Molecular function	18256285
RNGTT	8732	RNA guanylyltransferase and 5'-phosphatase	polynucleotide 5' dephosphorylation	Biological process	-
NXT2	55916	nuclear transport factor 2-like export factor 2	protein binding	Molecular function	16189514
PTGER4	5734	prostaglandin E receptor 4 (subtype EP4)	prostaglandin E receptor activity	Molecular function	8163486
SETX	23064	senataxin	protein kinase B signaling	Biological process	21576111
C2orf40	84417	chromosome 2 open reading frame 40	G1 to G0 transition	Biological process	-
RGR	5995	retinal G protein coupled receptor	visual perception	Biological process	-
IFNA14	3448	interferon, alpha 14	extracellular space	Cellular component	-
ARRB1	408	arrestin, beta 1	Notch signaling pathway	Biological process	-
CHGA	1113	chromogranin A	defense response to fungus	Biological process	-
SLC2A4	6517	solute carrier family 2 (facilitated glucose transporter), member 4	cellular response to osmotic stress	Biological process	-
ICAM1	3383	intercellular adhesion molecule 1	regulation of immune response	Biological process	-
HRAS	3265	Harvey rat sarcoma viral oncogene homolog	insulin receptor signaling pathway	Biological process	-
RUSC1	23623	RUN and SH3 domain containing 1	microtubule cytoskeleton	Cellular component	-
SERPINF2	5345	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2	serine-type endopeptidase inhibitor activity	Molecular function	12878203
ACVR1	90	activin A receptor, type I	atrial septum primum morphogenesis	Biological process	19506109
ELP2	55250	elongator acetyltransferase complex subunit 2	protein kinase binding	Molecular function	-
ORAI1	84876	ORAI calcium release-activated calcium modulator 1	calcium ion transmembrane transport	Biological process	-
ABCB8	11194	ATP-binding cassette, sub-family B (MDR/TAP), member 8	transmembrane transport	Biological process	-
ZNF826P	664701	zinc finger protein 826, pseudogene	DNA binding	Molecular function	-
CNOT1	23019	CCR4-NOT transcription complex, subunit 1	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	Biological process	21278420
NME1	4830	NME/NM23 nucleoside diphosphate kinase 1	GTP biosynthetic process	Biological process	-
DXO	1797	decapping exoribonuclease	mRNA binding	Molecular function	-
SMARCA2	6595	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	SWI/SNF complex	Cellular component	11078522
LRWD1	222229	leucine-rich repeats and WD repeat domain containing 1	pericentric heterochromatin	Cellular component	20932478
PAX6	5080	paired box 6	neuron fate commitment	Biological process	17291498
RNF169	254225	ring finger protein 169	nucleosome binding	Molecular function	22742833
APOA2	336	apolipoprotein A-II	phosphatidylcholine-sterol O-acyltransferase activator activity	Molecular function	14967812
EFNA5	1946	ephrin-A5	axon guidance	Biological process	-
CYLD	1540	cylindromatosis (turban tumor syndrome)	regulation of microtubule cytoskeleton organization	Biological process	20194890
PLCG1	5335	phospholipase C, gamma 1	calcium-mediated signaling	Biological process	22454520
ADTRP	84830	androgen-dependent TFPI-regulating protein	plasma membrane	Cellular component	-
PROX1	5629	prospero homeobox 1	ventricular cardiac myofibril assembly	Biological process	-
WEE2	494551	WEE1 homolog 2 (S. pombe)	nucleoplasm	Cellular component	-
ADSSL1	122622	adenylosuccinate synthase like 1	immune system process	Biological process	15786719
TUBA3C	7278	tubulin, alpha 3c	'de novo' posttranslational protein folding	Biological process	-
STAT1	6772	signal transducer and activator of transcription 1, 91kDa	blood circulation	Biological process	-
BBS7	55212	Bardet-Biedl syndrome 7	organelle organization	Biological process	-
IL9R	3581	interleukin 9 receptor	interleukin-9 binding	Molecular function	-
NEDD4L	23327	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase	response to metal ion	Biological process	11244092
CXCL13	10563	chemokine (C-X-C motif) ligand 13	regulation of humoral immune response	Biological process	16531331
ULK1	8408	unc-51 like autophagy activating kinase 1	autophagosome assembly	Biological process	-
TXNDC5	81567	thioredoxin domain containing 5 (endoplasmic reticulum)	cell redox homeostasis	Biological process	-
NR2E1	7101	nuclear receptor subfamily 2, group E, member 1	regulation of timing of neuron differentiation	Biological process	-
C5AR1	728	complement component 5a receptor 1	activation of MAPK activity	Biological process	7649993
DNAJC24	120526	DnaJ (Hsp40) homolog, subfamily C, member 24	ferrous iron binding	Molecular function	22367199
TRA2A	29896	transformer 2 alpha homolog (Drosophila)	poly(A) RNA binding	Molecular function	22658674
GNAZ	2781	guanine nucleotide binding protein (G protein), alpha z polypeptide	GTPase activity	Molecular function	-
CNOT6	57472	CCR4-NOT transcription complex, subunit 6	nuclear-transcribed mRNA poly(A) tail shortening	Biological process	-
PCDHB16	57717	protocadherin beta 16	plasma membrane	Cellular component	-
CXCR6	10663	chemokine (C-X-C motif) receptor 6	viral genome replication	Biological process	9230441
PIK3C3	5289	phosphatidylinositol 3-kinase, catalytic subunit type 3	phosphatidylinositol-3-phosphate biosynthetic process	Biological process	7628435
SLC13A3	64849	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3	transmembrane transport	Biological process	-
USP17L20	100287441	ubiquitin specific peptidase 17-like family member 20	cysteine-type endopeptidase activity	Molecular function	-
PTK2	5747	protein tyrosine kinase 2	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	-
SOX17	64321	SRY (sex determining region Y)-box 17	nucleus	Cellular component	17875931
CASK	8573	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	nuclear lamina	Cellular component	18664494
RBBP7	5931	retinoblastoma binding protein 7	cellular heat acclimation	Biological process	7503932
CCL11	6356	chemokine (C-C motif) ligand 11	positive regulation of endothelial cell proliferation	Biological process	19525930
BCKDHA	593	branched chain keto acid dehydrogenase E1, alpha polypeptide	cellular nitrogen compound metabolic process	Biological process	-
SP110	3431	SP110 nuclear body protein	signal transduction	Biological process	7693701
VAV1	7409	vav 1 guanine nucleotide exchange factor	platelet activation	Biological process	-
ANO1	55107	anoctamin 1, calcium activated chloride channel	ion transmembrane transport	Biological process	-
BCKDHB	594	branched chain keto acid dehydrogenase E1, beta polypeptide	cellular nitrogen compound metabolic process	Biological process	-
WNT3	7473	wingless-type MMTV integration site family, member 3	proteinaceous extracellular matrix	Cellular component	-
SEC31A	22872	SEC31 homolog A (S. cerevisiae)	ER to Golgi transport vesicle membrane	Cellular component	-
MREG	55686	melanoregulin	melanocyte differentiation	Biological process	-
RNF111	54778	ring finger protein 111	protein binding	Molecular function	16601693
DPP7	29952	dipeptidyl-peptidase 7	extracellular exosome	Cellular component	23376485
YKT6	10652	YKT6 v-SNARE homolog (S. cerevisiae)	retrograde transport, endosome to Golgi	Biological process	15215310
HSP90AA2P	3324	heat shock protein 90kDa alpha (cytosolic), class A member 2, pseudogene	biological_process	Biological process	-
FAM174B	400451	family with sequence similarity 174, member B	integral component of membrane	Cellular component	-
HPS4	89781	Hermansky-Pudlak syndrome 4	cytoplasm	Cellular component	12756248
RAB1B	81876	RAB1B, member RAS oncogene family	endoplasmic reticulum-Golgi intermediate compartment	Cellular component	-
GTF2H2	2966	general transcription factor IIH, polypeptide 2, 44kDa	positive regulation of viral transcription	Biological process	-
SUPT4H1	6827	suppressor of Ty 4 homolog 1 (S. cerevisiae)	positive regulation of transcription from RNA polymerase II promoter	Biological process	9450929
SPIN1	10927	spindlin 1	gamete generation	Biological process	-
STEAP3	55240	STEAP family member 3, metalloreductase	cupric reductase activity	Molecular function	-
CHMP1A	5119	charged multivesicular body protein 1A	negative regulation of transcription by glucose	Biological process	9837962
CLEC7A	64581	C-type lectin domain family 7, member A	phagocytosis, recognition	Biological process	11567029
FRMD4B	23150	FERM domain containing 4B	establishment of epithelial cell polarity	Biological process	-
RSF1	51773	remodeling and spacing factor 1	DNA-templated transcription, initiation	Biological process	9836642
RAB28	9364	RAB28, member RAS oncogene family	metabolic process	Biological process	8647132
PIK3C2A	5286	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha	vascular smooth muscle contraction	Biological process	17371240
SCN5A	6331	sodium channel, voltage gated, type V alpha subunit	ubiquitin protein ligase binding	Molecular function	15217910
HYAL1	3373	hyaluronoglucosaminidase 1	cellular response to tumor necrosis factor	Biological process	18390475
FBLIM1	54751	filamin binding LIM protein 1	cell cortex	Cellular component	-
ATP8B2	57198	ATPase, aminophospholipid transporter, class I, type 8B, member 2	ion transmembrane transport	Biological process	-
UBE2N	7334	ubiquitin-conjugating enzyme E2N	positive regulation of ubiquitin-protein transferase activity	Biological process	17349954
SDCBP	6386	syndecan binding protein (syntenin)	interleukin-5 receptor complex	Cellular component	11498591
KDM5D	8284	lysine (K)-specific demethylase 5D	DNA binding	Molecular function	-
ULBP1	80329	UL16 binding protein 1	antigen processing and presentation of peptide antigen via MHC class I	Biological process	-
SPHK1	8877	sphingosine kinase 1	protein phosphatase 2A binding	Molecular function	21075214
RAPGEF2	9693	Rap guanine nucleotide exchange factor (GEF) 2	negative regulation of cell proliferation	Biological process	16272156
PSMB2	5690	proteasome (prosome, macropain) subunit, beta type, 2	response to organic cyclic compound	Biological process	-
LHX1	3975	LIM homeobox 1	somite rostral/caudal axis specification	Biological process	-
SMPD2	6610	sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)	metal ion binding	Molecular function	-
PDCD5	9141	programmed cell death 5	protein binding	Molecular function	24012345
GOPC	57120	golgi-associated PDZ and coiled-coil motif containing	Golgi to plasma membrane transport	Biological process	11707463
TCF4	6925	transcription factor 4	TFIIB-class binding transcription factor activity	Molecular function	8978694
GOLPH3L	55204	golgi phosphoprotein 3-like	protein binding	Molecular function	23275563
CRMP1	1400	collapsin response mediator protein 1	protein binding	Molecular function	15383276
MECP2	4204	methyl CpG binding protein 2	sequence-specific DNA binding transcription factor activity	Molecular function	-
RAB38	23682	RAB38, member RAS oncogene family	melanosome	Cellular component	22511774
HPN	3249	hepsin	negative regulation of epithelial cell proliferation	Biological process	19843851
TRPM8	79054	transient receptor potential cation channel, subfamily M, member 8	response to cold	Biological process	-
SRD5A2	6716	steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)	response to follicle-stimulating hormone	Biological process	-
TMEM99	147184	transmembrane protein 99	integral component of membrane	Cellular component	-
PCCA	5095	propionyl CoA carboxylase, alpha polypeptide	short-chain fatty acid catabolic process	Biological process	-
TBP	6908	TATA box binding protein	regulation of gene expression, epigenetic	Biological process	-
DNM2	1785	dynamin 2	SH3 domain binding	Molecular function	18388313
FOS	2353	FBJ murine osteosarcoma viral oncogene homolog	sequence-specific DNA binding transcription factor activity	Molecular function	9732876
NOLC1	9221	nucleolar and coiled-body phosphoprotein 1	nucleoplasm	Cellular component	-
SLC12A3	6559	solute carrier family 12 (sodium/chloride transporter), member 3	transporter activity	Molecular function	-
TMED4	222068	transmembrane emp24 protein transport domain containing 4	endoplasmic reticulum membrane	Cellular component	-
FOS	2353	FBJ murine osteosarcoma viral oncogene homolog	stress-activated MAPK cascade	Biological process	-
SCARA5	286133	scavenger receptor class A, member 5	receptor-mediated endocytosis	Biological process	-
ZNF570	148268	zinc finger protein 570	regulation of transcription, DNA-templated	Biological process	-
PPP1R13L	10848	protein phosphatase 1, regulatory subunit 13 like	transcription corepressor activity	Molecular function	10336463
CDC37	11140	cell division cycle 37	protein targeting	Biological process	8666233
HDAC1	3065	histone deacetylase 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	16762839
BAK1	578	BCL2-antagonist/killer 1	positive regulation of apoptotic process	Biological process	17289999
RAB27A	5873	RAB27A, member RAS oncogene family	secretory granule	Cellular component	-
NGF	4803	nerve growth factor (beta polypeptide)	regulation of release of sequestered calcium ion into cytosol	Biological process	-
MUC20	200958	mucin 20, cell surface associated	cellular protein metabolic process	Biological process	-
ZDHHC18	84243	zinc finger, DHHC-type containing 18	protein-cysteine S-palmitoyltransferase activity	Molecular function	-
AHSP	51327	alpha hemoglobin stabilizing protein	hemoglobin binding	Molecular function	12066189
BCOR	54880	BCL6 corepressor	histone H2A monoubiquitination	Biological process	16943429
FGF10	2255	fibroblast growth factor 10	thymus development	Biological process	17969154
SLC34A2	10568	solute carrier family 34 (type II sodium/phosphate cotransporter), member 2	in utero embryonic development	Biological process	-
CD37	951	CD37 molecule	negative regulation of myeloid dendritic cell activation	Biological process	-
CTGF	1490	connective tissue growth factor	DNA biosynthetic process	Biological process	-
PLA2G2F	64600	phospholipase A2, group IIF	phosphatidylcholine acyl-chain remodeling	Biological process	-
SOX11	6664	SRY (sex determining region Y)-box 11	skeletal system development	Biological process	-
SMAD1	4086	SMAD family member 1	nucleoplasm	Cellular component	-
RBCK1	10616	RanBP-type and C3HC4-type zinc finger containing 1	positive regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	19136968
HNF1A	6927	HNF1 homeobox A	transcription, DNA-templated	Biological process	-
NCOA3	8202	nuclear receptor coactivator 3	protein binding	Molecular function	10866661
POLD1	5424	polymerase (DNA directed), delta 1, catalytic subunit	DNA binding	Molecular function	16762037
SYNCRIP	10492	synaptotagmin binding, cytoplasmic RNA interacting protein	osteoblast differentiation	Biological process	16210410
COL4A5	1287	collagen, type IV, alpha 5	neuromuscular junction	Cellular component	-
RHOBTB3	22836	Rho-related BTB domain containing 3	extracellular exosome	Cellular component	18570454
C1QTNF7	114905	C1q and tumor necrosis factor related protein 7	extracellular space	Cellular component	-
CCDC88B	283234	coiled-coil domain containing 88B	membrane	Cellular component	19946888
PAQR3	152559	progestin and adipoQ receptor family member III	Golgi apparatus	Cellular component	17724343
DICER1	23405	dicer 1, ribonuclease type III	multicellular organism growth	Biological process	-
IGF1	3479	insulin-like growth factor 1 (somatomedin C)	platelet alpha granule lumen	Cellular component	-
PSME2	5721	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	Biological process	-
STC2	8614	stanniocalcin 2	cellular calcium ion homeostasis	Biological process	-
KIF3B	9371	kinesin family member 3B	positive regulation of cytokinesis	Biological process	-
LPL	4023	lipoprotein lipase	triglyceride binding	Molecular function	-
POP4	10775	processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)	RNA phosphodiester bond hydrolysis	Biological process	10352175
RPUSD4	84881	RNA pseudouridylate synthase domain containing 4	pseudouridine synthase activity	Molecular function	-
MPDU1	9526	mannose-P-dolichol utilization defect 1	membrane	Cellular component	19946888
P2RX7	5027	purinergic receptor P2X, ligand gated ion channel, 7	NAD transport	Biological process	-
CLIC1	1192	chloride intracellular channel 1	nuclear membrane	Cellular component	-
IL22RA2	116379	interleukin 22 receptor, alpha 2	interleukin-22 binding	Molecular function	11390453
RPS4X	6191	ribosomal protein S4, X-linked	focal adhesion	Cellular component	21423176
FHL5	9457	four and a half LIM domains 5	zinc ion binding	Molecular function	-
POU3F3	5455	POU class 3 homeobox 3	negative regulation of apoptotic process	Biological process	-
NUP50	10762	nucleoporin 50kDa	protein binding	Molecular function	12802065
PXDN	7837	peroxidasin	extracellular matrix structural constituent	Molecular function	19590037
IL12B	3593	interleukin 12B	negative regulation of growth of symbiont in host	Biological process	-
OXTR	5021	oxytocin receptor	response to progesterone	Biological process	-
CYLD	1540	cylindromatosis (turban tumor syndrome)	centrosome	Cellular component	-
RUNX1	861	runt-related transcription factor 1	protein heterodimerization activity	Molecular function	8413232
DDRGK1	65992	DDRGK domain containing 1	response to endoplasmic reticulum stress	Biological process	-
CCNH	902	cyclin H	nucleoplasm	Cellular component	-
CA4	762	carbonic anhydrase IV	zinc ion binding	Molecular function	-
F9	2158	coagulation factor IX	post-translational protein modification	Biological process	-
PDPR	55066	pyruvate dehydrogenase phosphatase regulatory subunit	pyruvate metabolic process	Biological process	-
ACOX1	51	acyl-CoA oxidase 1, palmitoyl	receptor binding	Molecular function	20178365
NR1D2	9975	nuclear receptor subfamily 1, group D, member 2	regulation of lipid metabolic process	Biological process	-
RRAD	6236	Ras-related associated with diabetes	intracellular	Cellular component	8248782
SCARB1	949	scavenger receptor class B, member 1	regulation of phosphatidylcholine catabolic process	Biological process	-
TIE1	7075	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	protein binding	Molecular function	21982860
CD44	960	CD44 molecule (Indian blood group)	branching involved in ureteric bud morphogenesis	Biological process	-
E2F6	1876	E2F transcription factor 6	regulation of transcription involved in G1/S transition of mitotic cell cycle	Biological process	-
DOK1	1796	docking protein 1, 62kDa (downstream of tyrosine kinase 1)	transmembrane receptor protein tyrosine kinase signaling pathway	Biological process	9008160
KRT81	3887	keratin 81, type II	extracellular space	Cellular component	23580065
HBS1L	10767	HBS1-like translational GTPase	translation elongation factor activity	Molecular function	-
STK4	6789	serine/threonine kinase 4	keratinocyte differentiation	Biological process	-
ONECUT3	390874	one cut homeobox 3	transcription factor complex	Cellular component	-
TROVE2	6738	TROVE domain family, member 2	U2 snRNA binding	Molecular function	-
ZNF548	147694	zinc finger protein 548	metal ion binding	Molecular function	-
PSMD10	5716	proteasome (prosome, macropain) 26S subunit, non-ATPase, 10	small molecule metabolic process	Biological process	-
PTPN14	5784	protein tyrosine phosphatase, non-receptor type 14	transcription cofactor activity	Molecular function	22525271
CNGA1	1259	cyclic nucleotide gated channel alpha 1	rhodopsin mediated signaling pathway	Biological process	-
CSNK1A1	1452	casein kinase 1, alpha 1	protein kinase activity	Molecular function	10777483
FGD4	121512	FYVE, RhoGEF and PH domain containing 4	small GTPase mediated signal transduction	Biological process	-
C7orf72	100130988	chromosome 7 open reading frame 72	molecular_function	Molecular function	-
AIFM1	9131	apoptosis-inducing factor, mitochondrion-associated, 1	regulation of apoptotic DNA fragmentation	Biological process	-
MAP2K7	5609	mitogen-activated protein kinase kinase 7	response to UV	Biological process	9535930
DMD	1756	dystrophin	structural constituent of cytoskeleton	Molecular function	-
GATA2	2624	GATA binding protein 2	definitive hemopoiesis	Biological process	-
PCBP2	5094	poly(rC) binding protein 2	negative regulation of defense response to virus	Biological process	19881509
TBX2	6909	T-box 2	cardiac muscle tissue development	Biological process	-
P2RY10	27334	purinergic receptor P2Y, G-protein coupled, 10	plasma membrane	Cellular component	-
SH2D1A	4068	SH2 domain containing 1A	protein binding	Molecular function	10549287
SLC25A33	84275	solute carrier family 25 (pyrimidine nucleotide carrier), member 33	regulation of cell cycle arrest	Biological process	17596519
JPH2	57158	junctophilin 2	phosphatidylinositol-4-phosphate binding	Molecular function	24001019
NUP43	348995	nucleoporin 43kDa	transmembrane transport	Biological process	-
CDC37	11140	cell division cycle 37	mitogen-activated protein kinase kinase kinase binding	Molecular function	-
SLC9A3R1	9368	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1	microvillus	Cellular component	17242191
DLGAP3	58512	discs, large (Drosophila) homolog-associated protein 3	postsynaptic density	Cellular component	-
LIN28A	79727	lin-28 homolog A (C. elegans)	nucleolus	Cellular component	-
COL3A1	1281	collagen, type III, alpha 1	aging	Biological process	-
ZNF174	7727	zinc finger protein 174	cytoplasm	Cellular component	-
KIAA1598	57698	KIAA1598	protein binding	Molecular function	25416956
GATA6	2627	GATA binding protein 6	blood coagulation	Biological process	-
CTGF	1490	connective tissue growth factor	positive regulation of cardiac muscle contraction	Biological process	-
HYAL4	23553	hyaluronoglucosaminidase 4	cell surface	Cellular component	-
APOBEC3D	140564	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D	innate immune response	Biological process	-
AK2	204	adenylate kinase 2	response to thyroid hormone	Biological process	-
RNASEH1	246243	ribonuclease H1	mitochondrion	Cellular component	-
DPEP1	1800	dipeptidase 1 (renal)	antibiotic metabolic process	Biological process	8737157
MACC1	346389	metastasis associated in colon cancer 1	growth factor activity	Molecular function	-
GFY	100507003	golgi-associated, olfactory signaling regulator	sensory perception of smell	Biological process	-
ZNF705E	100131539	zinc finger protein 705E	nucleus	Cellular component	-
DOCK10	55619	dedicator of cytokinesis 10	Rho GTPase binding	Molecular function	-
CPS1	1373	carbamoyl-phosphate synthase 1, mitochondrial	homocysteine metabolic process	Biological process	20031578
SNAP25	6616	synaptosomal-associated protein, 25kDa	regulation of neuron projection development	Biological process	-
CXCL8	3576	chemokine (C-X-C motif) ligand 8	interleukin-8 receptor binding	Molecular function	1840701
CD3G	917	CD3g molecule, gamma (CD3-TCR complex)	innate immune response	Biological process	-
OR1G1	8390	olfactory receptor, family 1, subfamily G, member 1	signal transduction	Biological process	8004088
RPL7	6129	ribosomal protein L7	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Biological process	-
WNT1	7471	wingless-type MMTV integration site family, member 1	branching involved in ureteric bud morphogenesis	Biological process	-
EGR1	1958	early growth response 1	cellular response to mechanical stimulus	Biological process	-
KRT20	54474	keratin 20, type I	protein binding	Molecular function	16189514
IL6R	3570	interleukin 6 receptor	acute-phase response	Biological process	12832423
ZNF107	51427	zinc finger protein 107	biological_process	Biological process	-
SERPINA1	5265	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1	endoplasmic reticulum	Cellular component	20477988
YES1	7525	YES proto-oncogene 1, Src family tyrosine kinase	T cell costimulation	Biological process	-
GTF2B	2959	general transcription factor IIB	TBP-class protein binding	Molecular function	-
GHR	2690	growth hormone receptor	growth hormone receptor signaling pathway	Biological process	7565946
MAP3K9	4293	mitogen-activated protein kinase kinase kinase 9	positive regulation of apoptotic process	Biological process	-
MUCL1	118430	mucin-like 1	membrane	Cellular component	-
DNAH9	1770	dynein, axonemal, heavy chain 9	movement of cell or subcellular component	Biological process	8812413
SULT2A1	6822	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	bile acid catabolic process	Biological process	-
MRPL16	54948	mitochondrial ribosomal protein L16	rRNA binding	Molecular function	-
UBC	7316	ubiquitin C	virion assembly	Biological process	-
SCNN1D	6339	sodium channel, non voltage gated 1 delta subunit	sensory perception of taste	Biological process	-
OR2T29	343563	olfactory receptor, family 2, subfamily T, member 29	olfactory receptor activity	Molecular function	-
GAP43	2596	growth associated protein 43	protein kinase C-activating G-protein coupled receptor signaling pathway	Biological process	3272162
CBS	875	cystathionine-beta-synthase	modified amino acid binding	Molecular function	20031578
ERBB4	2066	erb-b2 receptor tyrosine kinase 4	mitochondrial matrix	Cellular component	-
MICALL1	85377	MICAL-like 1	late endosome membrane	Cellular component	-
POM121	9883	POM121 transmembrane nucleoporin	post-translational protein modification	Biological process	-
GATA4	2626	GATA binding protein 4	regulation of cardiac muscle cell contraction	Biological process	-
LAMTOR4	389541	late endosomal/lysosomal adaptor, MAPK and MTOR activator 4	lysosome	Cellular component	22980980
TULP3	7289	tubby like protein 3	regulation of G-protein coupled receptor protein signaling pathway	Biological process	20889716
APOA5	116519	apolipoprotein A-V	cholesterol biosynthetic process	Biological process	-
SYT1	6857	synaptotagmin I	regulation of calcium ion-dependent exocytosis	Biological process	-
TXNL4A	10907	thioredoxin-like 4A	mitotic nuclear division	Biological process	-
TGFBR3	7049	transforming growth factor, beta receptor III	cell growth	Biological process	1333192
ACOX3	8310	acyl-CoA oxidase 3, pristanoyl	receptor binding	Molecular function	20178365
FGF2	2247	fibroblast growth factor 2 (basic)	somatic stem cell maintenance	Biological process	-
ELFN2	114794	extracellular leucine-rich repeat and fibronectin type III domain containing 2	negative regulation of phosphatase activity	Biological process	19389623
INO80E	283899	INO80 complex subunit E	DNA repair	Biological process	-
SNCA	6622	synuclein, alpha (non A4 component of amyloid precursor)	long-term synaptic potentiation	Biological process	-
POLR2J	5439	polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa	7-methylguanosine mRNA capping	Biological process	-
WNT10B	7480	wingless-type MMTV integration site family, member 10B	extracellular region	Cellular component	-
EIF3H	8667	eukaryotic translation initiation factor 3, subunit H	extracellular exosome	Cellular component	19056867
RAB14	51552	RAB14, member RAS oncogene family	GTPase activity	Molecular function	15004230
TRAF3IP1	26146	TNF receptor-associated factor 3 interacting protein 1	centrosome	Cellular component	-
A1BG	1	alpha-1-B glycoprotein	blood microparticle	Cellular component	22516433
PLA2G4A	5321	phospholipase A2, group IVA (cytosolic, calcium-dependent)	phosphatidylethanolamine acyl-chain remodeling	Biological process	-
RHBG	57127	Rh family, B glycoprotein (gene/pseudogene)	cytoplasmic vesicle membrane	Cellular component	-
DLX6	1750	distal-less homeobox 6	skeletal system development	Biological process	7907794
IER3IP1	51124	immediate early response 3 interacting protein 1	regulation of fibroblast apoptotic process	Biological process	21835305
MYRFL	196446	myelin regulatory factor-like	sequence-specific DNA binding transcription factor activity	Molecular function	-
FKBP1A	2280	FK506 binding protein 1A, 12kDa	activin binding	Molecular function	16720724
ERO1LB	56605	ERO1-like beta (S. cerevisiae)	endoplasmic reticulum	Cellular component	10818100
ZNF107	51427	zinc finger protein 107	transcription, DNA-templated	Biological process	-
CCL5	6352	chemokine (C-C motif) ligand 5	chemokine receptor binding	Molecular function	7517217
ZFPM2	23414	zinc finger protein, FOG family member 2	transcription, DNA-templated	Biological process	-
APELA	100506013	apelin receptor early endogenous ligand	cell migration involved in mesendoderm migration	Biological process	-
JAG2	3714	jagged 2	in utero embryonic development	Biological process	-
DTNA	1837	dystrobrevin, alpha	sarcolemma	Cellular component	-
ATP7B	540	ATPase, Cu++ transporting, beta polypeptide	mitochondrion	Cellular component	-
DIO1	1733	deiodinase, iodothyronine, type I	thyroid hormone generation	Biological process	-
SOX8	30812	SRY (sex determining region Y)-box 8	peripheral nervous system development	Biological process	-
ATP5C1	509	ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1	cellular metabolic process	Biological process	-
MAPRE1	22919	microtubule-associated protein, RP/EB family, member 1	mitotic cell cycle	Biological process	-
C1orf116	79098	chromosome 1 open reading frame 116	biological_process	Biological process	-
ZNF213	7760	zinc finger protein 213	regulation of transcription, DNA-templated	Biological process	-
VPS16	64601	vacuolar protein sorting 16 homolog (S. cerevisiae)	HOPS complex	Cellular component	19109425
NR0B1	190	nuclear receptor subfamily 0, group B, member 1	intracellular receptor signaling pathway	Biological process	9384387
BCR	613	breakpoint cluster region	protein tyrosine kinase activity	Molecular function	-
OR51I1	390063	olfactory receptor, family 51, subfamily I, member 1	G-protein coupled receptor activity	Molecular function	-
SOCS1	8651	suppressor of cytokine signaling 1	protein ubiquitination	Biological process	-
ACAT2	39	acetyl-CoA acetyltransferase 2	nucleus	Cellular component	-
EXOSC7	23016	exosome component 7	RNA binding	Molecular function	11849973
ZC3H3	23144	zinc finger CCCH-type containing 3	regulation of mRNA export from nucleus	Biological process	19364924
OR5AL1	79482	olfactory receptor, family 5, subfamily AL, member 1 (gene/pseudogene)	plasma membrane	Cellular component	-
COL18A1	80781	collagen, type XVIII, alpha 1	positive regulation of cell proliferation	Biological process	-
AHCYL1	10768	adenosylhomocysteinase-like 1	cytoplasm	Cellular component	-
CALCOCO1	57658	calcium binding and coiled-coil domain 1	nuclear chromatin	Cellular component	-
HEYL	26508	hes-related family bHLH transcription factor with YRPW motif-like	negative regulation of androgen receptor activity	Biological process	21454491
PPARGC1A	10891	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	RNA binding	Molecular function	12588810
P2RY6	5031	pyrimidinergic receptor P2Y, G-protein coupled, 6	integral component of plasma membrane	Cellular component	8670200
ABCA1	19	ATP-binding cassette, sub-family A (ABC1), member 1	reverse cholesterol transport	Biological process	10431236
EPHX1	2052	epoxide hydrolase 1, microsomal (xenobiotic)	epoxide hydrolase activity	Molecular function	7516776
DLG1	1739	discs, large homolog 1 (Drosophila)	synaptic transmission	Biological process	-
MMAA	166785	methylmalonic aciduria (cobalamin deficiency) cblA type	cellular lipid metabolic process	Biological process	-
DCTN3	11258	dynactin 3 (p22)	mitotic cell cycle	Biological process	-
PSME3	10197	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)	MDM2/MDM4 family protein binding	Molecular function	18309296
LIPE	3991	lipase, hormone-sensitive	protein binding	Molecular function	17026959
PPM1L	151742	protein phosphatase, Mg2+/Mn2+ dependent, 1L	protein serine/threonine phosphatase activity	Molecular function	-
CYP8B1	1582	cytochrome P450, family 8, subfamily B, polypeptide 1	lipid metabolic process	Biological process	-
HOXA5	3202	homeobox A5	protein binding	Molecular function	15545268
CCS	9973	copper chaperone for superoxide dismutase	positive regulation of oxidoreductase activity	Biological process	-
SMC3	9126	structural maintenance of chromosomes 3	DNA repair	Biological process	-
CAV3	859	caveolin 3	caveola assembly	Biological process	18936328
MDFI	4188	MyoD family inhibitor	transcription factor binding	Molecular function	-
ADAM17	6868	ADAM metallopeptidase domain 17	cell adhesion	Biological process	14970227
UBE2C	11065	ubiquitin-conjugating enzyme E2C	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
IL3RA	3563	interleukin 3 receptor, alpha (low affinity)	cellular response to interleukin-3	Biological process	1833064
ALDH4A1	8659	aldehyde dehydrogenase 4 family, member A1	glutamate biosynthetic process	Biological process	-
ZNF680	340252	zinc finger protein 680	nucleus	Cellular component	-
SLC26A7	115111	solute carrier family 26 (anion exchanger), member 7	oxalate transport	Biological process	1183472
APOH	350	apolipoprotein H (beta-2-glycoprotein I)	identical protein binding	Molecular function	18822289
MT3	4504	metallothionein 3	positive regulation of transcription, DNA-templated	Biological process	-
BMPR2	659	bone morphogenetic protein receptor, type II (serine/threonine kinase)	negative regulation of chondrocyte proliferation	Biological process	9442116
SLC30A5	64924	solute carrier family 30 (zinc transporter), member 5	cellular protein metabolic process	Biological process	-
CATSPER1	117144	cation channel, sperm associated 1	spermatogenesis	Biological process	-
DNASE1	1773	deoxyribonuclease I	endodeoxyribonuclease activity	Molecular function	-
GIPC2	54810	GIPC PDZ domain containing family, member 2	biological_process	Biological process	-
RHOB	388	ras homolog family member B	cellular response to ionizing radiation	Biological process	21373644
SYTL1	84958	synaptotagmin-like 1	Rab GTPase binding	Molecular function	-
CHRNA1	1134	cholinergic receptor, nicotinic, alpha 1 (muscle)	synaptic transmission	Biological process	-
EXOSC5	56915	exosome component 5	exoribonuclease activity	Molecular function	17174896
GATA4	2626	GATA binding protein 4	atrial septum morphogenesis	Biological process	12845333
CRYZ	1429	crystallin, zeta (quinone reductase)	extracellular exosome	Cellular component	19056867
DIO1	1733	deiodinase, iodothyronine, type I	plasma membrane	Cellular component	-
HPN	3249	hepsin	cochlea morphogenesis	Biological process	-
TGFB1	7040	transforming growth factor, beta 1	viral life cycle	Biological process	-
TGFBRAP1	9392	transforming growth factor, beta receptor associated protein 1	vesicle-mediated transport	Biological process	-
ATG7	10533	autophagy related 7	cerebellar Purkinje cell layer development	Biological process	-
CHAC1	79094	ChaC glutathione-specific gamma-glutamylcyclotransferase 1	negative regulation of protein processing	Biological process	22445366
NTRK3	4916	neurotrophic tyrosine kinase, receptor, type 3	modulation by virus of host transcription	Biological process	-
MAPK3	5595	mitogen-activated protein kinase 3	response to epidermal growth factor	Biological process	18794356
FAT1	2195	FAT atypical cadherin 1	nucleus	Cellular component	15922730
APOC2	344	apolipoprotein C-II	phospholipase binding	Molecular function	10727238
SP1	6667	Sp1 transcription factor	embryonic process involved in female pregnancy	Biological process	-
PSMC2	5701	proteasome (prosome, macropain) 26S subunit, ATPase, 2	apoptotic process	Biological process	-
GSTM3	2947	glutathione S-transferase mu 3 (brain)	glutathione derivative biosynthetic process	Biological process	-
PSMC3	5702	proteasome (prosome, macropain) 26S subunit, ATPase, 3	ATPase activity	Molecular function	1429620
RPL27A	6157	ribosomal protein L27a	cellular protein metabolic process	Biological process	-
CCR4	1233	chemokine (C-C motif) receptor 4	inflammatory response	Biological process	-
TRIM15	89870	tripartite motif containing 15	mesodermal cell fate determination	Biological process	10207104
P2RX7	5027	purinergic receptor P2X, ligand gated ion channel, 7	reactive oxygen species metabolic process	Biological process	-
EML1	2009	echinoderm microtubule associated protein like 1	hematopoietic progenitor cell differentiation	Biological process	-
ERGIC2	51290	ERGIC and golgi 2	endoplasmic reticulum-Golgi intermediate compartment membrane	Cellular component	-
STK26	51765	serine/threonine protein kinase 26	extracellular exosome	Cellular component	23533145
SSH2	85464	slingshot protein phosphatase 2	actin cytoskeleton organization	Biological process	11832213
PDHA1	5160	pyruvate dehydrogenase (lipoamide) alpha 1	tricarboxylic acid cycle	Biological process	19081061
CYP17A1	1586	cytochrome P450, family 17, subfamily A, polypeptide 1	sex differentiation	Biological process	9326943
CD70	970	CD70 molecule	integral component of plasma membrane	Cellular component	8120384
OAZ1	4946	ornithine decarboxylase antizyme 1	positive regulation of protein catabolic process	Biological process	-
BMPR1A	657	bone morphogenetic protein receptor, type IA	transforming growth factor beta receptor signaling pathway	Biological process	8397373
CDC14A	8556	cell division cycle 14A	spindle	Cellular component	-
ITGA2	3673	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	hypotonic response	Biological process	-
UCHL5	51377	ubiquitin carboxyl-terminal hydrolase L5	negative regulation of transforming growth factor beta receptor signaling pathway	Biological process	-
MUC20	200958	mucin 20, cell surface associated	extracellular region	Cellular component	-
CACNG8	59283	calcium channel, voltage-dependent, gamma subunit 8	cell junction	Cellular component	-
AGO2	27161	argonaute RISC catalytic component 2	translational initiation	Biological process	10534406
CHIA	27159	chitinase, acidic	extracellular region	Cellular component	-
AZU1	566	azurocidin 1	protein processing	Biological process	-
ZNF226	7769	zinc finger protein 226	nucleus	Cellular component	-
SUOX	6821	sulfite oxidase	molybdopterin cofactor binding	Molecular function	-
ZNF705F	790969	zinc finger protein 705F	transcription, DNA-templated	Biological process	-
SPACA3	124912	sperm acrosome associated 3	positive regulation of phagocytosis	Biological process	11591365
ZBTB37	84614	zinc finger and BTB domain containing 37	regulation of transcription, DNA-templated	Biological process	-
CDK5RAP3	80279	CDK5 regulatory subunit associated protein 3	negative regulation of protein phosphorylation	Biological process	17785205
EDN2	1907	endothelin 2	regulation of systemic arterial blood pressure by endothelin	Biological process	2649896
IDH3B	3420	isocitrate dehydrogenase 3 (NAD+) beta	cellular metabolic process	Biological process	-
FYCO1	79443	FYVE and coiled-coil domain containing 1	integral component of membrane	Cellular component	-
NR4A2	4929	nuclear receptor subfamily 4, group A, member 2	cellular response to extracellular stimulus	Biological process	7877627
GEMIN2	8487	gem (nuclear organelle) associated protein 2	SMN-Sm protein complex	Cellular component	18984161
PLCB3	5331	phospholipase C, beta 3 (phosphatidylinositol-specific)	protein complex	Cellular component	18468998
FBXO6	26270	F-box protein 6	DNA damage checkpoint	Biological process	19716789
GSX2	170825	GS homeobox 2	telencephalon regionalization	Biological process	-
ASB2	51676	ankyrin repeat and SOCS box containing 2	protein binding	Molecular function	16325183
TXNIP	10628	thioredoxin interacting protein	innate immune response	Biological process	-
PDE2A	5138	phosphodiesterase 2A, cGMP-stimulated	cellular response to macrophage colony-stimulating factor stimulus	Biological process	14687666
HIST1H3B	8358	histone cluster 1, H3b	protein complex	Cellular component	14718166
CYTH3	9265	cytohesin 3	trans-Golgi network	Cellular component	-
PF4V1	5197	platelet factor 4 variant 1	inflammatory response	Biological process	-
UGT2B11	10720	UDP glucuronosyltransferase 2 family, polypeptide B11	flavonoid glucuronidation	Biological process	-
CHMP2A	27243	charged multivesicular body protein 2A	nucleus organization	Biological process	20616062
ZSCAN10	84891	zinc finger and SCAN domain containing 10	nucleus	Cellular component	-
CLC	1178	Charcot-Leyden crystal galectin	T cell apoptotic process	Biological process	17502455
SMN1	6606	survival of motor neuron 1, telomeric	identical protein binding	Molecular function	16189514
BAD	572	BCL2-associated agonist of cell death	cellular response to nicotine	Biological process	18676776
P2RY1	5028	purinergic receptor P2Y, G-protein coupled, 1	dendrite	Cellular component	-
CAPN11	11131	calpain 11	calcium ion binding	Molecular function	-
HLA-DRB4	3126	major histocompatibility complex, class II, DR beta 4	positive regulation of insulin secretion involved in cellular response to glucose stimulus	Biological process	-
GOPC	57120	golgi-associated PDZ and coiled-coil motif containing	regulation of catalytic activity	Biological process	-
SPON2	10417	spondin 2, extracellular matrix protein	cellular response to lipopolysaccharide	Biological process	-
DUSP16	80824	dual specificity phosphatase 16	nucleus	Cellular component	11489891
SSH2	85464	slingshot protein phosphatase 2	peptidyl-tyrosine dephosphorylation	Biological process	-
CTSH	1512	cathepsin H	proteolysis involved in cellular protein catabolic process	Biological process	-
NFKB1	4790	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	toll-like receptor 4 signaling pathway	Biological process	-
STAR	6770	steroidogenic acute regulatory protein	cellular response to cadmium ion	Biological process	-
MTX1	4580	metaxin 1	protein targeting to mitochondrion	Biological process	-
HVCN1	84329	hydrogen voltage gated channel 1	plasma membrane	Cellular component	-
ZDHHC13	54503	zinc finger, DHHC-type containing 13	positive regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	12761501
ZNF649	65251	zinc finger protein 649	regulation of transcription, DNA-templated	Biological process	-
ZNF592	9640	zinc finger protein 592	metal ion binding	Molecular function	-
OR5T1	390155	olfactory receptor, family 5, subfamily T, member 1	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
GOT1	2805	glutamic-oxaloacetic transaminase 1, soluble	axon terminus	Cellular component	-
SRC	6714	SRC proto-oncogene, non-receptor tyrosine kinase	response to mechanical stimulus	Biological process	-
SCN10A	6336	sodium channel, voltage gated, type X alpha subunit	bundle of His cell action potential	Biological process	24998131
UBE2A	7319	ubiquitin-conjugating enzyme E2A	nuclear chromatin	Cellular component	-
ROGDI	79641	rogdi homolog (Drosophila)	nuclear envelope	Cellular component	-
SGK1	6446	serum/glucocorticoid regulated kinase 1	cytosol	Cellular component	-
PCOLCE	5118	procollagen C-endopeptidase enhancer	extracellular matrix	Cellular component	20551380
CYP20A1	57404	cytochrome P450, family 20, subfamily A, polypeptide 1	oxidation-reduction process	Biological process	-
ZKSCAN1	7586	zinc finger with KRAB and SCAN domains 1	protein binding	Molecular function	25416956
DPM1	8813	dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit	mannose binding	Molecular function	-
PRKAR1B	5575	protein kinase, cAMP-dependent, regulatory, type I, beta	protein phosphorylation	Biological process	1708242
C3orf58	205428	chromosome 3 open reading frame 58	cardiac muscle cell proliferation	Biological process	23784961
STX8	9482	syntaxin 8	early endosome to late endosome transport	Biological process	10564279
CYP51A1	1595	cytochrome P450, family 51, subfamily A, polypeptide 1	small molecule metabolic process	Biological process	-
PIAS4	51588	protein inhibitor of activated STAT, 4	protein binding	Molecular function	11388671
FBXL3	26224	F-box and leucine-rich repeat protein 3	cytoplasm	Cellular component	-
CASP5	838	caspase 5, apoptosis-related cysteine peptidase	NLRP3 inflammasome complex	Cellular component	-
MYD88	4615	myeloid differentiation primary response 88	toll-like receptor 5 signaling pathway	Biological process	-
NFS1	9054	NFS1 cysteine desulfurase	vitamin metabolic process	Biological process	-
CCKAR	886	cholecystokinin A receptor	feeding behavior	Biological process	8503909
CDK1	983	cyclin-dependent kinase 1	positive regulation of protein import into nucleus, translocation	Biological process	-
SLC27A3	11000	solute carrier family 27 (fatty acid transporter), member 3	membrane	Cellular component	19946888
RAB38	23682	RAB38, member RAS oncogene family	GTP binding	Molecular function	10910072
FAM132A	388581	family with sequence similarity 132, member A	positive regulation of glucose import	Biological process	-
ZNF66	7617	zinc finger protein 66	DNA binding	Molecular function	-
C1R	715	complement component 1, r subcomponent	complement activation, classical pathway	Biological process	-
EIF2B1	1967	eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa	membrane	Cellular component	9235896
SEC62	7095	SEC62 homolog (S. cerevisiae)	endoplasmic reticulum	Cellular component	-
BAG2	9532	BCL2-associated athanogene 2	chaperone binding	Molecular function	-
KAT7	11143	K(lysine) acetyltransferase 7	nucleoplasm	Cellular component	-
ANKRD6	22881	ankyrin repeat domain 6	negative regulation of canonical Wnt signaling pathway	Biological process	-
PTPN1	5770	protein tyrosine phosphatase, non-receptor type 1	zinc ion binding	Molecular function	18074158
CHEK2	11200	checkpoint kinase 2	cell division	Biological process	-
ZDHHC17	23390	zinc finger, DHHC-type containing 17	integral component of membrane	Cellular component	-
SAT1	6303	spermidine/spermine N1-acetyltransferase 1	angiogenesis	Biological process	11866539
CPA2	1358	carboxypeptidase A2 (pancreatic)	vacuole	Cellular component	2920728
FKBP10	60681	FK506 binding protein 10, 65 kDa	chaperone-mediated protein folding	Biological process	-
NRD1	4898	nardilysin (N-arginine dibasic convertase)	proteolysis	Biological process	9581555
WNT5A	7474	wingless-type MMTV integration site family, member 5A	embryonic skeletal system development	Biological process	19918918
CNTN2	6900	contactin 2 (axonal)	anchored component of membrane	Cellular component	-
TAT	6898	tyrosine aminotransferase	biosynthetic process	Biological process	-
EEF1D	1936	eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)	gene expression	Biological process	-
LMF1	64788	lipase maturation factor 1	protein secretion	Biological process	-
HDLBP	3069	high density lipoprotein binding protein	plasma membrane	Cellular component	1318310
TRDN	10345	triadin	heart contraction	Biological process	22422768
LRG1	116844	leucine-rich alpha-2-glycoprotein 1	biological_process	Biological process	-
YBX3	8531	Y box binding protein 3	polysome	Cellular component	-
ARSA	410	arylsulfatase A	calcium ion binding	Molecular function	12888274
GNAT1	2779	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1	response to light intensity	Biological process	-
OR4N2	390429	olfactory receptor, family 4, subfamily N, member 2	G-protein coupled receptor activity	Molecular function	-
TUFT1	7286	tuftelin 1	bone mineralization	Biological process	12489194
TRPV4	59341	transient receptor potential cation channel, subfamily V, member 4	calcium ion transmembrane transport	Biological process	-
CUX1	1523	cut-like homeobox 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
ADCK4	79934	aarF domain containing kinase 4	mitochondrial membrane	Cellular component	-
BAK1	578	BCL2-antagonist/killer 1	fibroblast apoptotic process	Biological process	-
ABCF1	23	ATP-binding cassette, sub-family F (GCN20), member 1	polysomal ribosome	Cellular component	19570978
RWDD3	25950	RWD domain containing 3	nucleus	Cellular component	-
SBNO2	22904	strawberry notch homolog 2 (Drosophila)	transcription, DNA-templated	Biological process	-
PROM1	8842	prominin 1	extracellular exosome	Cellular component	19056867
CXCL1	2919	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	negative regulation of cell proliferation	Biological process	9551928
CDKN2A	1029	cyclin-dependent kinase inhibitor 2A	regulation of apoptotic DNA fragmentation	Biological process	12082630
SLC28A1	9154	solute carrier family 28 (concentrative nucleoside transporter), member 1	transmembrane transport	Biological process	-
WT1	7490	Wilms tumor 1	epithelial cell differentiation	Biological process	-
GSTA5	221357	glutathione S-transferase alpha 5	glutathione metabolic process	Biological process	-
HAUS1	115106	HAUS augmin-like complex, subunit 1	cytoplasm	Cellular component	-
UCN	7349	urocortin	perikaryon	Cellular component	-
TPM1	7168	tropomyosin 1 (alpha)	muscle thin filament tropomyosin	Cellular component	8205619
BMP4	652	bone morphogenetic protein 4	monocyte differentiation	Biological process	21149635
CALCR	799	calcitonin receptor	positive regulation of adenylate cyclase activity	Biological process	15563840
THTPA	79178	thiamine triphosphatase	hydrolase activity	Molecular function	11827967
ZNF623	9831	zinc finger protein 623	regulation of transcription, DNA-templated	Biological process	-
LAMB3	3914	laminin, beta 3	extracellular region	Cellular component	-
CYTH1	9267	cytohesin 1	cytoplasm	Cellular component	12606567
LRP1	4035	low density lipoprotein receptor-related protein 1	protein complex binding	Molecular function	8626514
CYBA	1535	cytochrome b-245, alpha polypeptide	protein binding	Molecular function	11733522
PRKAR1A	5573	protein kinase, cAMP-dependent, regulatory, type I, alpha	cAMP-dependent protein kinase complex	Cellular component	-
SLC5A2	6524	solute carrier family 5 (sodium/glucose cotransporter), member 2	carbohydrate metabolic process	Biological process	8244402
KCNMB4	27345	potassium channel subfamily M regulatory beta subunit 4	blood coagulation	Biological process	-
TNKS	8658	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase	negative regulation of DNA binding	Biological process	9822378
HBA1	3039	hemoglobin, alpha 1	positive regulation of cell death	Biological process	19740759
CDC25C	995	cell division cycle 25C	regulation of cell cycle	Biological process	-
SUSD6	9766	sushi domain containing 6	molecular_function	Molecular function	-
GPER1	2852	G protein-coupled estrogen receptor 1	negative regulation of leukocyte activation	Biological process	23285008
PTPN2	5771	protein tyrosine phosphatase, non-receptor type 2	negative regulation of prolactin signaling pathway	Biological process	-
DUSP3	1845	dual specificity phosphatase 3	protein kinase binding	Molecular function	22572157
RHOA	387	ras homolog family member A	trabecula morphogenesis	Biological process	-
TAS2R16	50833	taste receptor, type 2, member 16	detection of chemical stimulus involved in sensory perception of bitter taste	Biological process	16720576
CD22	933	CD22 molecule	carbohydrate binding	Molecular function	-
STMN4	81551	stathmin-like 4	cytoplasm	Cellular component	-
CD55	1604	CD55 molecule, decay accelerating factor for complement (Cromer blood group)	extracellular exosome	Cellular component	19199708
MPP3	4356	membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)	nucleotide phosphorylation	Biological process	8824795
FN1	2335	fibronectin 1	protease binding	Molecular function	22952693
ABCE1	6059	ATP-binding cassette, sub-family E (OABP), member 1	mitochondrial matrix	Cellular component	-
ZNF92	168374	zinc finger protein 92	regulation of transcription, DNA-templated	Biological process	-
KIAA0368	23392	KIAA0368	protein binding	Molecular function	25416956
NEDD4	4734	neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase	chromatin	Cellular component	17996703
CNBP	7555	CCHC-type zinc finger, nucleic acid binding protein	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
DNAJC9	23234	DnaJ (Hsp40) homolog, subfamily C, member 9	social behavior	Biological process	21531385
SDF2L1	23753	stromal cell-derived factor 2-like 1	chaperone binding	Molecular function	-
RPS5	6193	ribosomal protein S5	extracellular exosome	Cellular component	20458337
GPER1	2852	G protein-coupled estrogen receptor 1	chromatin binding	Molecular function	20551055
RRM1	6240	ribonucleotide reductase M1	protein heterotetramerization	Biological process	-
TARBP1	6894	TAR (HIV-1) RNA binding protein 1	nucleus	Cellular component	8846792
TOR4A	54863	torsin family 4, member A	ATP binding	Molecular function	-
ITM2C	81618	integral membrane protein 2C	lysosomal membrane	Cellular component	-
GOLGA2	2801	golgin A2	Golgi cis cisterna	Cellular component	17488291
FXYD2	486	FXYD domain containing ion transport regulator 2	extracellular exosome	Cellular component	19056867
NOX1	27035	NADPH oxidase 1	small GTPase mediated signal transduction	Biological process	-
CBR3	874	carbonyl reductase 3	3-keto sterol reductase activity	Molecular function	-
IFNA8	3445	interferon, alpha 8	cytokine activity	Molecular function	-
CXCL5	6374	chemokine (C-X-C motif) ligand 5	chemokine-mediated signaling pathway	Biological process	-
SH2D6	284948	SH2 domain containing 6	cytoplasm	Cellular component	-
DNALI1	7802	dynein, axonemal, light intermediate chain 1	cytoplasm	Cellular component	19944400
TOE1	114034	target of EGR1, member 1 (nuclear)	nucleolus	Cellular component	-
CHD8	57680	chromodomain helicase DNA binding protein 8	negative regulation of Wnt signaling pathway	Biological process	18378692
HIST1H4K	8362	histone cluster 1, H4k	gene expression	Biological process	-
BGN	633	biglycan	extracellular matrix binding	Molecular function	-
INO80D	54891	INO80 complex subunit D	nucleus	Cellular component	-
GMEB2	26205	glucocorticoid modulatory element binding protein 2	nucleoplasm	Cellular component	-
MAPK8IP2	23542	mitogen-activated protein kinase 8 interacting protein 2	regulation of synaptic transmission, glutamatergic	Biological process	-
MCIDAS	345643	multiciliate differentiation and DNA synthesis associated cell cycle protein	nucleus	Cellular component	21543332
ETNK1	55500	ethanolamine kinase 1	nucleoplasm	Cellular component	-
ZBTB21	49854	zinc finger and BTB domain containing 21	regulation of transcription from RNA polymerase II promoter	Biological process	-
LOC100133495	100133495	HERV-K_11q22.1 provirus ancestral Pol protein [Includes: Reverse transcriptase	RNA-dependent DNA replication	Biological process	-
FAM27E3	100131997	family with sequence similarity 27, member E3	protein binding	Molecular function	25416956
SPHK1	8877	sphingosine kinase 1	response to amine	Biological process	-
RBPMS	11030	RNA binding protein with multiple splicing	positive regulation of pathway-restricted SMAD protein phosphorylation	Biological process	17099224
AARS	16	alanyl-tRNA synthetase	tRNA binding	Molecular function	-
NRTN	4902	neurturin	nerve development	Biological process	-
FTHL17	53940	ferritin, heavy polypeptide-like 17	ferric iron binding	Molecular function	-
LATS1	9113	large tumor suppressor kinase 1	negative regulation of cyclin-dependent protein serine/threonine kinase activity	Biological process	9988268
MTBP	27085	MDM2 binding protein	cell cycle arrest	Biological process	-
NPAT	4863	nuclear protein, ataxia-telangiectasia locus	protein C-terminus binding	Molecular function	15988025
EMD	2010	emerin	mitotic nuclear envelope reassembly	Biological process	-
ENG	2022	endoglin	response to transforming growth factor beta	Biological process	-
SOX9	6662	SRY (sex determining region Y)-box 9	transcription from RNA polymerase II promoter	Biological process	-
GOLGA8J	653073	golgin A8 family, member J	Golgi apparatus	Cellular component	-
XDH	7498	xanthine dehydrogenase	negative regulation of vascular endothelial growth factor signaling pathway	Biological process	18386220
TBL1XR1	79718	transducin (beta)-like 1 X-linked receptor 1	protein binding	Molecular function	12628926
RGS12	6002	regulator of G-protein signaling 12	regulation of G-protein coupled receptor protein signaling pathway	Biological process	9651375
ANXA7	310	annexin A7	response to salt stress	Biological process	-
SLC5A4	6527	solute carrier family 5 (glucose activated ion channel), member 4	transmembrane transport	Biological process	-
THOC5	8563	THO complex 5	viral mRNA export from host cell nucleus	Biological process	18974867
RIPK3	11035	receptor-interacting serine-threonine kinase 3	protein complex binding	Molecular function	22265414
GCNT4	51301	glucosaminyl (N-acetyl) transferase 4, core 2	inter-male aggressive behavior	Biological process	-
LRWD1	222229	leucine-rich repeats and WD repeat domain containing 1	chromatin binding	Molecular function	20932478
HTRA2	27429	HtrA serine peptidase 2	neuron development	Biological process	-
FRG1	2483	FSHD region gene 1	protein binding	Molecular function	22365833
MTIF2	4528	mitochondrial translational initiation factor 2	mitochondrial translation	Biological process	-
SSX8	280659	synovial sarcoma, X breakpoint 8	nucleic acid binding	Molecular function	-
SLC4A11	83959	solute carrier family 4, sodium borate transporter, member 11	regulation of intracellular pH	Biological process	-
PCYT1B	9468	phosphate cytidylyltransferase 1, choline, beta	phospholipid metabolic process	Biological process	-
CALM1	801	calmodulin 1 (phosphorylase kinase, delta)	cytosol	Cellular component	-
EIF2B4	8890	eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa	positive regulation of GTPase activity	Biological process	15054402
BCL9	607	B-cell CLL/lymphoma 9	protein binding	Molecular function	11955446
CHCHD1	118487	coiled-coil-helix-coiled-coil-helix domain containing 1	cytoplasm	Cellular component	-
RALB	5899	v-ral simian leukemia viral oncogene homolog B	regulation of exocyst assembly	Biological process	-
NOTCH4	4855	notch 4	embryo development	Biological process	-
TRAF4	9618	TNF receptor-associated factor 4	tumor necrosis factor receptor binding	Molecular function	11728344
GNB2L1	10399	guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1	protein homodimerization activity	Molecular function	24947010
IBTK	25998	inhibitor of Bruton agammaglobulinemia tyrosine kinase	nucleoplasm	Cellular component	-
KIF18B	146909	kinesin family member 18B	plasma membrane	Cellular component	-
ASIC1	41	acid sensing (proton gated) ion channel 1	sensory perception of sour taste	Biological process	19812697
CPSF3	51692	cleavage and polyadenylation specific factor 3, 73kDa	mRNA 3'-end processing	Biological process	-
ITGB3BP	23421	integrin beta 3 binding protein (beta3-endonexin)	membrane	Cellular component	7593198
DLL1	28514	delta-like 1 (Drosophila)	Notch receptor processing	Biological process	-
CS	1431	citrate synthase	nucleus	Cellular component	21630459
WNT9B	7484	wingless-type MMTV integration site family, member 9B	cell-cell signaling	Biological process	9441749
FOSL1	8061	FOS-like antigen 1	response to corticosterone	Biological process	-
AANAT	15	aralkylamine N-acetyltransferase	arylamine N-acetyltransferase activity	Molecular function	-
IDH3G	3421	isocitrate dehydrogenase 3 (NAD+) gamma	carbohydrate metabolic process	Biological process	9286695
ACTR1A	10121	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)	antigen processing and presentation of exogenous peptide antigen via MHC class II	Biological process	-
ANXA2	302	annexin A2	positive regulation of binding	Biological process	-
OR52E8	390079	olfactory receptor, family 52, subfamily E, member 8	G-protein coupled receptor activity	Molecular function	-
PNPLA4	8228	patatin-like phospholipase domain containing 4	triglyceride lipase activity	Molecular function	-
UFSP2	55325	UFM1-specific peptidase 2	proteolysis	Biological process	25219498
COBL	23242	cordon-bleu WH2 repeat protein	actin filament network formation	Biological process	-
KCNK5	8645	potassium channel, two pore domain subfamily K, member 5	potassium ion leak channel activity	Molecular function	-
BCAS2	10286	breast carcinoma amplified sequence 2	cell junction	Cellular component	-
SLC11A1	6556	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1	transition metal ion transmembrane transporter activity	Molecular function	17932044
PNPLA2	57104	patatin-like phospholipase domain containing 2	phospholipid metabolic process	Biological process	-
HPGD	3248	hydroxyprostaglandin dehydrogenase 15-(NAD)	prostaglandin metabolic process	Biological process	16828555
SDHD	6392	succinate dehydrogenase complex, subunit D, integral membrane protein	regulation of catecholamine secretion	Biological process	-
LIG1	3978	ligase I, DNA, ATP-dependent	DNA ligation	Biological process	15871698
MBD3	53615	methyl-CpG binding domain protein 3	nuclear chromatin	Cellular component	16217013
FBXL2	25827	F-box and leucine-rich repeat protein 2	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological process	23604317
KDM8	79831	lysine (K)-specific demethylase 8	nucleus	Cellular component	20457893
ZNF789	285989	zinc finger protein 789	sequence-specific DNA binding transcription factor activity	Molecular function	-
CTNND1	1500	catenin (cadherin-associated protein), delta 1	synapse	Cellular component	-
DLL4	54567	delta-like 4 (Drosophila)	angiogenesis	Biological process	-
GCG	2641	glucagon	cellular protein metabolic process	Biological process	-
SLMAP	7871	sarcolemma associated protein	integral component of plasma membrane	Cellular component	9405447
MGST1	4257	microsomal glutathione S-transferase 1	protein homodimerization activity	Molecular function	-
ATF4	468	activating transcription factor 4	positive regulation of gene expression	Biological process	24939851
TRPM3	80036	transient receptor potential cation channel, subfamily M, member 3	detection of temperature stimulus	Biological process	-
PLSCR1	5359	phospholipid scramblase 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	16091359
PARK2	5071	parkin RBR E3 ubiquitin protein ligase	protein K48-linked ubiquitination	Biological process	21376232
SH2D1B	117157	SH2 domain containing 1B	intracellular	Cellular component	16920955
HDAC4	9759	histone deacetylase 4	negative regulation of transcription, DNA-templated	Biological process	19276356
LRSAM1	90678	leucine rich repeat and sterile alpha motif containing 1	protein autoubiquitination	Biological process	15256501
XPC	7508	xeroderma pigmentosum, complementation group C	protein sumoylation	Biological process	-
UXT	8409	ubiquitously-expressed, prefoldin-like chaperone	centrosome	Cellular component	16221885
DVL2	1856	dishevelled segment polarity protein 2	nucleus	Cellular component	-
MS4A2	2206	membrane-spanning 4-domains, subfamily A, member 2	Fc-epsilon receptor signaling pathway	Biological process	-
IFNG	3458	interferon, gamma	endoplasmic reticulum unfolded protein response	Biological process	-
PRKACB	5567	protein kinase, cAMP-dependent, catalytic, beta	renal water homeostasis	Biological process	-
MAP3K7	6885	mitogen-activated protein kinase kinase kinase 7	toll-like receptor TLR1:TLR2 signaling pathway	Biological process	-
CCNH	902	cyclin H	gene expression	Biological process	-
CACNG2	10369	calcium channel, voltage-dependent, gamma subunit 2	voltage-gated calcium channel activity	Molecular function	-
RPA2	6118	replication protein A2, 32kDa	mismatch repair	Biological process	-
KIF2B	84643	kinesin family member 2B	metabolic process	Biological process	-
SRI	6717	sorcin	receptor binding	Molecular function	9668070
CALM1	801	calmodulin 1 (phosphorylase kinase, delta)	nitric oxide metabolic process	Biological process	-
MAGEL2	54551	melanoma antigen family L2	Arp2/3 complex-mediated actin nucleation	Biological process	23452853
PRKACA	5566	protein kinase, cAMP-dependent, catalytic, alpha	ubiquitin protein ligase binding	Molecular function	21423175
WNT1	7471	wingless-type MMTV integration site family, member 1	hepatocyte differentiation	Biological process	-
COL7A1	1294	collagen, type VII, alpha 1	negative regulation of endopeptidase activity	Biological process	-
WHAMM	123720	WAS protein homolog associated with actin, golgi membranes and microtubules	cytoplasm	Cellular component	-
P2RX1	5023	purinergic receptor P2X, ligand gated ion channel, 1	external side of cell outer membrane	Cellular component	-
SERINC5	256987	serine incorporator 5	myelination	Biological process	-
LARGE	9215	like-glycosyltransferase	glycoprotein biosynthetic process	Biological process	9892679
SCNN1G	6340	sodium channel, non voltage gated 1 gamma subunit	transmembrane transport	Biological process	-
KNG1	3827	kininogen 1	receptor binding	Molecular function	11290596
HSP90AB1	3326	heat shock protein 90kDa alpha (cytosolic), class B member 1	extracellular exosome	Cellular component	20458337
HSD17B3	3293	hydroxysteroid (17-beta) dehydrogenase 3	endoplasmic reticulum membrane	Cellular component	-
MYO1C	4641	myosin IC	plasma membrane	Cellular component	-
SEC61G	23480	Sec61 gamma subunit	translation	Biological process	-
CXXC5	51523	CXXC finger protein 5	signal transducer activity	Molecular function	12761501
CTAGE3P	220112	CTAGE family, member 3, pseudogene	biological_process	Biological process	-
ZAK	51776	sterile alpha motif and leucine zipper containing kinase AZK	cytoskeleton organization	Biological process	-
NAIP	4671	NLR family, apoptosis inhibitory protein	mitotic spindle assembly	Biological process	-
EGR1	1958	early growth response 1	transcription factor binding	Molecular function	-
RNF24	11237	ring finger protein 24	integral component of membrane	Cellular component	-
VIL1	7429	villin 1	protein binding	Molecular function	16921170
ULK4	54986	unc-51 like kinase 4	regulation of MAPK cascade	Biological process	24284070
MUS81	80198	MUS81 structure-specific endonuclease subunit	DNA catabolic process, endonucleolytic	Biological process	23361013
ZNF114	163071	zinc finger protein 114	transcription, DNA-templated	Biological process	-
EHBP1	23301	EH domain binding protein 1	plasma membrane	Cellular component	-
RGS12	6002	regulator of G-protein signaling 12	nuclear matrix	Cellular component	-
SNAP29	9342	synaptosomal-associated protein, 29kDa	cell junction	Cellular component	-
NPY2R	4887	neuropeptide Y receptor Y2	cytosol	Cellular component	-
LYVE1	10894	lymphatic vessel endothelial hyaluronan receptor 1	extracellular exosome	Cellular component	23376485
SKIL	6498	SKI-like proto-oncogene	acrosomal vesicle	Cellular component	-
CHRDL1	91851	chordin-like 1	extracellular region	Cellular component	-
RTN4	57142	reticulon 4	regulation of axonogenesis	Biological process	-
CEACAM5	1048	carcinoembryonic antigen-related cell adhesion molecule 5	protein homodimerization activity	Molecular function	18086185
SCYL2	55681	SCY1-like 2 (S. cerevisiae)	protein phosphorylation	Biological process	-
ANGPT1	284	angiopoietin 1	cell-substrate adhesion	Biological process	-
GSTP1	2950	glutathione S-transferase pi 1	negative regulation of MAPK cascade	Biological process	18962899
ADRB2	154	adrenoceptor beta 2, surface	activation of adenylate cyclase activity	Biological process	15123695
CREB3	10488	cAMP responsive element binding protein 3	DNA binding	Molecular function	10675342
OR4C6	219432	olfactory receptor, family 4, subfamily C, member 6	G-protein coupled receptor activity	Molecular function	-
RER1	11079	retention in endoplasmic reticulum sorting receptor 1	cell surface	Cellular component	-
COL1A1	1277	collagen, type I, alpha 1	sensory perception of sound	Biological process	17489845
SNAI2	6591	snail family zinc finger 2	sensory perception of sound	Biological process	12444107
TGFBR2	7048	transforming growth factor, beta receptor II (70/80kDa)	organ regeneration	Biological process	-
SS18L1	26039	synovial sarcoma translocation gene on chromosome 18-like 1	nucleus	Cellular component	-
C14orf166	51637	chromosome 14 open reading frame 166	identical protein binding	Molecular function	15147888
PIFO	128344	primary cilia formation	ciliary basal body	Cellular component	-
PDCD10	11235	programmed cell death 10	positive regulation of cell migration	Biological process	20332113
CXCR6	10663	chemokine (C-X-C motif) receptor 6	plasma membrane	Cellular component	-
DRD2	1813	dopamine receptor D2	adult walking behavior	Biological process	-
NINJ1	4814	ninjurin 1	tissue regeneration	Biological process	-
PDLIM5	10611	PDZ and LIM domain 5	zinc ion binding	Molecular function	-
SSBP1	6742	single-stranded DNA binding protein 1, mitochondrial	chromatin binding	Molecular function	18063578
RGS20	8601	regulator of G-protein signaling 20	plasma membrane	Cellular component	-
MSRB1	51734	methionine sulfoxide reductase B1	methionine-R-sulfoxide reductase activity	Molecular function	-
ZNF30	90075	zinc finger protein 30	nucleus	Cellular component	-
SIRT1	23411	sirtuin 1	regulation of peroxisome proliferator activated receptor signaling pathway	Biological process	-
UCN2	90226	urocortin 2	negative regulation of follicle-stimulating hormone secretion	Biological process	-
CNBP	7555	CCHC-type zinc finger, nucleic acid binding protein	positive regulation of transcription, DNA-templated	Biological process	-
CDH12	1010	cadherin 12, type 2 (N-cadherin 2)	integral component of membrane	Cellular component	-
JUND	3727	jun D proto-oncogene	response to cytokine	Biological process	-
GALNTL5	168391	polypeptide N-acetylgalactosaminyltransferase-like 5	protein glycosylation	Biological process	24398516
RNF150	57484	ring finger protein 150	zinc ion binding	Molecular function	-
TGFB1	7040	transforming growth factor, beta 1	positive regulation of SMAD protein import into nucleus	Biological process	19366691
ADAR	103	adenosine deaminase, RNA-specific	supraspliceosomal complex	Cellular component	18362360
OR2AG1	144125	olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene)	G-protein coupled receptor signaling pathway	Biological process	-
SERPINF2	5345	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2	blood coagulation	Biological process	-
FSHR	2492	follicle stimulating hormone receptor	female gonad development	Biological process	7553856
HOXD11	3237	homeobox D11	transcription, DNA-templated	Biological process	-
FKBP1A	2280	FK506 binding protein 1A, 12kDa	ion channel binding	Molecular function	11322937
SPCS2	9789	signal peptidase complex subunit 2 homolog (S. cerevisiae)	translation	Biological process	-
MTF1	4520	metal-regulatory transcription factor 1	transcription coactivator activity	Molecular function	3208749
TLR8	51311	toll-like receptor 8	I-kappaB kinase/NF-kappaB signaling	Biological process	12032557
TTBK2	146057	tau tubulin kinase 2	centriole	Cellular component	-
LFNG	3955	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	ovarian follicle development	Biological process	-
CPEB4	80315	cytoplasmic polyadenylation element binding protein 4	cellular response to amino acid stimulus	Biological process	-
PRKAG2	51422	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	energy reserve metabolic process	Biological process	-
AGTR2	186	angiotensin II receptor, type 2	renin-angiotensin regulation of aldosterone production	Biological process	-
IKBKAP	8518	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein	positive regulation of cell migration	Biological process	-
TRIP12	9320	thyroid hormone receptor interactor 12	thyroid hormone receptor binding	Molecular function	7776974
PSMC1	5700	proteasome (prosome, macropain) 26S subunit, ATPase, 1	protein binding	Molecular function	16189514
TFAM	7019	transcription factor A, mitochondrial	positive regulation of transcription from RNA polymerase II promoter	Biological process	20410300
ACVR1	90	activin A receptor, type I	regulation of skeletal muscle tissue development	Biological process	-
MSX2	4488	msh homeobox 2	positive regulation of BMP signaling pathway	Biological process	-
TFAP2A	7020	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	positive regulation of transcription from RNA polymerase II promoter	Biological process	11278550
PDE9A	5152	phosphodiesterase 9A	Golgi apparatus	Cellular component	-
DACT1	51339	dishevelled-binding antagonist of beta-catenin 1	regulation of nodal signaling pathway	Biological process	17197390
ITGAX	3687	integrin, alpha X (complement component 3 receptor 4 subunit)	positive regulation of protein targeting to mitochondrion	Biological process	24270810
CMTM7	112616	CKLF-like MARVEL transmembrane domain containing 7	B-1a B cell differentiation	Biological process	-
XRCC2	7516	X-ray repair complementing defective repair in Chinese hamster cells 2	meiotic nuclear division	Biological process	9628903
SLCO2B1	11309	solute carrier organic anion transporter family, member 2B1	sodium-independent organic anion transmembrane transporter activity	Molecular function	18501590
DKK3	27122	dickkopf WNT signaling pathway inhibitor 3	Wnt signaling pathway	Biological process	-
CD3E	916	CD3e molecule, epsilon (CD3-TCR complex)	regulation of apoptotic process	Biological process	12567487
SERPINB2	5055	serpin peptidase inhibitor, clade B (ovalbumin), member 2	extracellular space	Cellular component	-
SELP	6403	selectin P (granule membrane protein 140kDa, antigen CD62)	protein binding	Molecular function	11237770
C1QL3	389941	complement component 1, q subcomponent-like 3	regulation of synapse organization	Biological process	-
OR9K2	441639	olfactory receptor, family 9, subfamily K, member 2	G-protein coupled receptor signaling pathway	Biological process	-
TBR1	10716	T-box, brain, 1	hindbrain development	Biological process	-
NPY2R	4887	neuropeptide Y receptor Y2	locomotory behavior	Biological process	9692752
NFKB2	4791	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	cytoplasm	Cellular component	-
BAIAP2L2	80115	BAI1-associated protein 2-like 2	cell-cell contact zone	Cellular component	21743456
GPR146	115330	G protein-coupled receptor 146	G-protein coupled receptor activity	Molecular function	-
MYH8	4626	myosin, heavy chain 8, skeletal muscle, perinatal	ATP metabolic process	Biological process	17041932
MAP3K4	4216	mitogen-activated protein kinase kinase kinase 4	perinuclear region of cytoplasm	Cellular component	-
TEK	7010	TEK tyrosine kinase, endothelial	cell surface	Cellular component	19689429
SLC35D2	11046	solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2	pyrimidine nucleotide-sugar transmembrane transport	Biological process	-
NEK10	152110	NIMA-related kinase 10	ATP binding	Molecular function	-
HOXD13	3239	homeobox D13	skeletal system development	Biological process	-
TACR3	6870	tachykinin receptor 3	nucleus	Cellular component	-
PTPRC	5788	protein tyrosine phosphatase, receptor type, C	T cell receptor signaling pathway	Biological process	-
FAM200B	285550	family with sequence similarity 200, member B	nucleic acid binding	Molecular function	-
LEO1	123169	Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	histone H2B ubiquitination	Biological process	16307923
ACAN	176	aggrecan	keratan sulfate metabolic process	Biological process	-
PTPRO	5800	protein tyrosine phosphatase, receptor type, O	phosphatase activity	Molecular function	-
GAN	8139	gigaxonin	protein ubiquitination	Biological process	-
APOE	348	apolipoprotein E	negative regulation of lipid biosynthetic process	Biological process	12042316
EEA1	8411	early endosome antigen 1	calmodulin binding	Molecular function	11741531
RAB8B	51762	RAB8B, member RAS oncogene family	receptor binding	Molecular function	18346465
DKK1	22943	dickkopf WNT signaling pathway inhibitor 1	positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway	Biological process	-
BRAT1	221927	BRCA1-associated ATM activator 1	nucleus	Cellular component	16452482
SIGMAR1	10280	sigma non-opioid intracellular receptor 1	integral component of membrane	Cellular component	9453537
ST3GAL4	6484	ST3 beta-galactoside alpha-2,3-sialyltransferase 4	dolichol-linked oligosaccharide biosynthetic process	Biological process	-
WRNIP1	56897	Werner helicase interacting protein 1	DNA binding	Molecular function	-
PAICS	10606	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase	purine ribonucleoside monophosphate biosynthetic process	Biological process	-
ACOT8	10005	acyl-CoA thioesterase 8	palmitoyl-CoA hydrolase activity	Molecular function	9299485
ZNF710	374655	zinc finger protein 710	metal ion binding	Molecular function	-
FAM126A	84668	family with sequence similarity 126, member A	plasma membrane	Cellular component	-
LMF1	64788	lipase maturation factor 1	Golgi apparatus	Cellular component	-
CD320	51293	CD320 molecule	endosome membrane	Cellular component	-
NNMT	4837	nicotinamide N-methyltransferase	response to organonitrogen compound	Biological process	-
AP2A2	161	adaptor-related protein complex 2, alpha 2 subunit	neurotrophin TRK receptor signaling pathway	Biological process	-
ARRB1	408	arrestin, beta 1	transcription factor binding	Molecular function	16325578
FBXO5	26271	F-box protein 5	protein binding	Molecular function	11988738
EHD2	30846	EH-domain containing 2	caveola	Cellular component	24013648
CRYBA1	1411	crystallin, beta A1	molecular_function	Molecular function	-
ERBB2IP	55914	erbb2 interacting protein	epidermal growth factor receptor signaling pathway	Biological process	11375975
DPY19L2P1	554236	DPY19L2 pseudogene 1	metabolic process	Biological process	-
RALB	5899	v-ral simian leukemia viral oncogene homolog B	positive regulation of protein binding	Biological process	24056301
MLEC	9761	malectin	cellular protein metabolic process	Biological process	-
HS3ST4	9951	heparan sulfate (glucosamine) 3-O-sulfotransferase 4	integral component of membrane	Cellular component	-
KCNJ12	3768	potassium channel, inwardly rectifying subfamily J, member 12	regulation of ion transmembrane transport	Biological process	-
UGT1A9	54600	UDP glucuronosyltransferase 1 family, polypeptide A9	enzyme inhibitor activity	Molecular function	20610558
YY1	7528	YY1 transcription factor	response to UV-C	Biological process	18026119
SUGT1	10910	SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)	mitotic nuclear division	Biological process	10445024
DDHD1	80821	DDHD domain containing 1	cytoplasm	Cellular component	-
IHH	3549	indian hedgehog	pancreas development	Biological process	-
PANX1	24145	pannexin 1	endoplasmic reticulum membrane	Cellular component	-
NPHS1	4868	nephrosis 1, congenital, Finnish type (nephrin)	glomerular basement membrane development	Biological process	17464107
NODAL	4838	nodal growth differentiation factor	floor plate morphogenesis	Biological process	-
NLRP1	22861	NLR family, pyrin domain containing 1	positive regulation of interleukin-1 beta secretion	Biological process	-
CHTOP	26097	chromatin target of PRMT1	nuclear speck	Cellular component	23299939
ARPC4	10093	actin related protein 2/3 complex, subunit 4, 20kDa	protein binding	Molecular function	11162547
LRRN1	57633	leucine rich repeat neuronal 1	integral component of membrane	Cellular component	-
EGR1	1958	early growth response 1	nucleoplasm	Cellular component	-
SULF2	55959	sulfatase 2	heparan sulfate proteoglycan metabolic process	Biological process	12368295
UBE2B	7320	ubiquitin-conjugating enzyme E2B	ubiquitin-dependent protein catabolic process	Biological process	1559696
SRPK3	26576	SRSF protein kinase 3	cell differentiation	Biological process	-
TSNARE1	203062	t-SNARE domain containing 1	SNARE binding	Molecular function	-
MRC2	9902	mannose receptor, C type 2	focal adhesion	Cellular component	21423176
CALHM3	119395	calcium homeostasis modulator 3	ion transmembrane transport	Biological process	-
MRPL39	54148	mitochondrial ribosomal protein L39	mitochondrial ribosome	Cellular component	11167009
P2RX1	5023	purinergic receptor P2X, ligand gated ion channel, 1	transport	Biological process	9565569
ASPA	443	aspartoacylase	extracellular exosome	Cellular component	23376485
GALNT14	79623	polypeptide N-acetylgalactosaminyltransferase 14	polypeptide N-acetylgalactosaminyltransferase activity	Molecular function	-
DNAJC10	54431	DnaJ (Hsp40) homolog, subfamily C, member 10	disulfide oxidoreductase activity	Molecular function	-
SHC4	399694	SHC (Src homology 2 domain containing) family, member 4	postsynaptic membrane	Cellular component	-
HIST4H4	121504	histone cluster 4, H4	protein complex	Cellular component	14718166
FGF12	2257	fibroblast growth factor 12	JNK cascade	Biological process	12815063
DHRS9	10170	dehydrogenase/reductase (SDR family) member 9	9-cis-retinoic acid biosynthetic process	Biological process	11304534
RPL26L1	51121	ribosomal protein L26-like 1	translational termination	Biological process	-
RXRB	6257	retinoid X receptor, beta	in utero embryonic development	Biological process	-
HDAC9	9734	histone deacetylase 9	histone H3-K9 deacetylation	Biological process	-
CDK12	51755	cyclin-dependent kinase 12	regulation of cell cycle	Biological process	-
PRKCE	5581	protein kinase C, epsilon	signal transducer activity	Molecular function	10438519
AP1AR	55435	adaptor-related protein complex 1 associated regulatory protein	vesicle targeting, trans-Golgi to endosome	Biological process	19706427
EHD1	10938	EH-domain containing 1	early endosome membrane	Cellular component	15020713
PHF8	23133	PHD finger protein 8	histone demethylase activity (H3-K9 specific)	Molecular function	20023638
ORAI2	80228	ORAI calcium release-activated calcium modulator 2	membrane	Cellular component	-
RTTN	25914	rotatin	ciliary basal body	Cellular component	22939636
SLC22A1	6580	solute carrier family 22 (organic cation transporter), member 1	transmembrane transport	Biological process	-
OR6M1	390261	olfactory receptor, family 6, subfamily M, member 1	olfactory receptor activity	Molecular function	-
ABCG1	9619	ATP-binding cassette, sub-family G (WHITE), member 1	ATP binding	Molecular function	16702602
MAP3K7	6885	mitogen-activated protein kinase kinase kinase 7	transcription, DNA-templated	Biological process	-
PTK2B	2185	protein tyrosine kinase 2 beta	negative regulation of muscle cell apoptotic process	Biological process	-
ZFP36	7538	ZFP36 ring finger protein	protein kinase binding	Molecular function	15014438
HAX1	10456	HCLS1 associated protein X-1	regulation of apoptotic process	Biological process	24522549
PCYOX1	51449	prenylcysteine oxidase 1	chloride transmembrane transport	Biological process	-
PPM1M	132160	protein phosphatase, Mg2+/Mn2+ dependent, 1M	CTD phosphatase activity	Molecular function	-
ANXA2	302	annexin A2	perinuclear region of cytoplasm	Cellular component	-
TAF5	6877	TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa	nucleoplasm	Cellular component	-
N4BP2	55728	NEDD4 binding protein 2	cytosol	Cellular component	-
CRKL	1399	v-crk avian sarcoma virus CT10 oncogene homolog-like	blood vessel development	Biological process	-
VAV1	7409	vav 1 guanine nucleotide exchange factor	integrin-mediated signaling pathway	Biological process	-
PID1	55022	phosphotyrosine interaction domain containing 1	negative regulation of ATP biosynthetic process	Biological process	20165904
HIATL2	84278	hippocampus abundant transcript-like 2	integral component of membrane	Cellular component	-
VASH1	22846	vasohibin 1	negative regulation of endothelial cell proliferation	Biological process	15467828
SRSF9	8683	serine/arginine-rich splicing factor 9	mRNA splice site selection	Biological process	7556075
ABCA8	10351	ATP-binding cassette, sub-family A (ABC1), member 8	ATP binding	Molecular function	-
LHX2	9355	LIM homeobox 2	axon extension	Biological process	-
FADS2P1	643181	fatty acid desaturase 2 pseudogene 1	endoplasmic reticulum membrane	Cellular component	-
NEBL	10529	nebulette	protein binding	Molecular function	11309420
SIN3A	25942	SIN3 transcription regulator family member A	cellular response to glucose stimulus	Biological process	-
ZNF462	58499	zinc finger protein 462	transcription, DNA-templated	Biological process	-
GPER1	2852	G protein-coupled estrogen receptor 1	nuclear fragmentation involved in apoptotic nuclear change	Biological process	-
HMGB1	3146	high mobility group box 1	transcriptional repressor complex	Cellular component	19158276
GRAMD1A	57655	GRAM domain containing 1A	integral component of membrane	Cellular component	-
CPS1	1373	carbamoyl-phosphate synthase 1, mitochondrial	carbamoyl phosphate biosynthetic process	Biological process	7416778
PDGFA	5154	platelet-derived growth factor alpha polypeptide	regulation of DNA biosynthetic process	Biological process	11788434
TUBA1C	84790	tubulin, alpha 1c	microtubule-based process	Biological process	12090300
XBP1	7494	X-box binding protein 1	liver development	Biological process	-
USP47	55031	ubiquitin specific peptidase 47	SCF ubiquitin ligase complex	Cellular component	19966869
KCNK4	50801	potassium channel, two pore domain subfamily K, member 4	potassium ion transmembrane transport	Biological process	22282805
STEAP3	55240	STEAP family member 3, metalloreductase	transferrin transport	Biological process	-
CYP1A1	1543	cytochrome P450, family 1, subfamily A, polypeptide 1	response to hypoxia	Biological process	-
PIK3C3	5289	phosphatidylinositol 3-kinase, catalytic subunit type 3	phosphatidylinositol 3-kinase complex, class III, type I	Cellular component	-
FGF8	2253	fibroblast growth factor 8 (androgen-induced)	dorsal/ventral axon guidance	Biological process	-
S1PR1	1901	sphingosine-1-phosphate receptor 1	sphingosine-1-phosphate signaling pathway	Biological process	22344443
DNMT3B	1789	DNA (cytosine-5-)-methyltransferase 3 beta	gene expression	Biological process	-
RAP2A	5911	RAP2A, member of RAS oncogene family	protein localization to plasma membrane	Biological process	22797597
CYCS	54205	cytochrome c, somatic	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity	Molecular function	8689682
SOX11	6664	SRY (sex determining region Y)-box 11	glial cell proliferation	Biological process	-
PTK2B	2185	protein tyrosine kinase 2 beta	positive regulation of JUN kinase activity	Biological process	-
GIGYF2	26058	GRB10 interacting GYF protein 2	insulin-like growth factor receptor signaling pathway	Biological process	-
JUN	3725	jun proto-oncogene	negative regulation of neuron apoptotic process	Biological process	-
IGF1	3479	insulin-like growth factor 1 (somatomedin C)	skeletal system development	Biological process	10448861
USP17L2	377630	ubiquitin specific peptidase 17-like family member 2	cell cycle checkpoint	Biological process	20228808
ILK	3611	integrin-linked kinase	protein binding	Molecular function	11331582
FOXR1	283150	forkhead box R1	anatomical structure morphogenesis	Biological process	-
MYH13	8735	myosin, heavy chain 13, skeletal muscle	muscle contraction	Biological process	10388558
MED20	9477	mediator complex subunit 20	protein binding	Molecular function	14576168
CTCF	10664	CCCTC-binding factor (zinc finger protein)	positive regulation of gene expression	Biological process	18347100
CHMP2B	25978	charged multivesicular body protein 2B	nucleoplasm	Cellular component	-
THAP7	80764	THAP domain containing 7	protein binding	Molecular function	16189514
SETD8	387893	SET domain containing (lysine methyltransferase) 8	protein-lysine N-methyltransferase activity	Molecular function	17707234
RNF7	9616	ring finger protein 7	response to redox state	Biological process	10082581
TTC9B	148014	tetratricopeptide repeat domain 9B	protein peptidyl-prolyl isomerization	Biological process	-
APITD1	378708	apoptosis-inducing, TAF9-like domain 1	chromatin binding	Molecular function	20347429
OR4C13	283092	olfactory receptor, family 4, subfamily C, member 13	integral component of membrane	Cellular component	-
CDK14	5218	cyclin-dependent kinase 14	nucleus	Cellular component	-
SEC14L1	6397	SEC14-like 1 (S. cerevisiae)	integral component of membrane	Cellular component	-
SERPINB2	5055	serpin peptidase inhibitor, clade B (ovalbumin), member 2	fibrinolysis	Biological process	-
CAV1	857	caveolin 1, caveolae protein, 22kDa	mammary gland development	Biological process	-
CYP2C8	1558	cytochrome P450, family 2, subfamily C, polypeptide 8	iron ion binding	Molecular function	-
DNAI1	27019	dynein, axonemal, intermediate chain 1	cilium	Cellular component	10577904
CADM1	23705	cell adhesion molecule 1	receptor binding	Molecular function	12826663
SYNJ1	8867	synaptojanin 1	membrane coat	Cellular component	-
APMAP	57136	adipocyte plasma membrane associated protein	extracellular exosome	Cellular component	23376485
FLOT1	10211	flotillin 1	positive regulation of cell adhesion molecule production	Biological process	25204797
RASGRP2	10235	RAS guanyl releasing protein 2 (calcium and DAG-regulated)	plasma membrane	Cellular component	10918068
PIK3R3	8503	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)	phosphatidylinositol biosynthetic process	Biological process	-
SPPL2A	84888	signal peptide peptidase like 2A	integral component of cytoplasmic side of endoplasmic reticulum membrane	Cellular component	15385547
USP17L8	392188	ubiquitin specific peptidase 17-like family member 8	nucleus	Cellular component	-
TMEM43	79188	transmembrane protein 43	Golgi apparatus	Cellular component	-
MICALL1	85377	MICAL-like 1	protein targeting to membrane	Biological process	19864458
NECAP1	25977	NECAP endocytosis associated 1	clathrin vesicle coat	Cellular component	-
OR4C45	403257	olfactory receptor, family 4, subfamily C, member 45	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
OR5M11	219487	olfactory receptor, family 5, subfamily M, member 11	odorant binding	Molecular function	-
SCIN	85477	scinderin	actin filament binding	Molecular function	-
PYCARD	29108	PYD and CARD domain containing	positive regulation of NF-kappaB transcription factor activity	Biological process	12646168
ACLY	47	ATP citrate lyase	cofactor binding	Molecular function	-
PBX1	5087	pre-B-cell leukemia homeobox 1	transcription, DNA-templated	Biological process	-
TMEM57	55219	transmembrane protein 57	synapse	Cellular component	15255972
UBR4	23352	ubiquitin protein ligase E3 component n-recognin 4	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	23932781
MLST8	64223	MTOR associated protein, LST8 homolog (S. cerevisiae)	innate immune response	Biological process	-
SYVN1	84447	synovial apoptosis inhibitor 1, synoviolin	zinc ion binding	Molecular function	-
CRIPAK	285464	cysteine-rich PAK1 inhibitor	protein binding	Molecular function	16278681
PPP2R1A	5518	protein phosphatase 2, regulatory subunit A, alpha	RNA splicing	Biological process	11007961
PDCD6	10016	programmed cell death 6	protein homodimerization activity	Molecular function	-
COL11A2	1302	collagen, type XI, alpha 2	extracellular matrix disassembly	Biological process	-
MYO5A	4644	myosin VA (heavy chain 12, myoxin)	extracellular exosome	Cellular component	23533145
HIST3H2A	92815	histone cluster 3, H2a	extracellular exosome	Cellular component	23533145
UTP20	27340	UTP20, small subunit (SSU) processome component, homolog (yeast)	small-subunit processome	Cellular component	15590835
FOXJ1	2302	forkhead box J1	leukocyte migration	Biological process	-
PTPRK	5796	protein tyrosine phosphatase, receptor type, K	axon	Cellular component	-
MTCL1	23255	microtubule crosslinking factor 1	lateral plasma membrane	Cellular component	-
PELO	53918	pelota homolog (Drosophila)	nuclear-transcribed mRNA catabolic process, no-go decay	Biological process	-
ZNF385D	79750	zinc finger protein 385D	zinc ion binding	Molecular function	-
TNF	7124	tumor necrosis factor	recycling endosome	Cellular component	-
RPS6KA5	9252	ribosomal protein S6 kinase, 90kDa, polypeptide 5	axon guidance	Biological process	-
HPS1	3257	Hermansky-Pudlak syndrome 1	eye pigmentation	Biological process	-
DAPK3	1613	death-associated protein kinase 3	positive regulation of apoptotic process	Biological process	21487036
FER	2241	fer (fps/fes related) tyrosine kinase	extrinsic component of cytoplasmic side of plasma membrane	Cellular component	19738202
MAPRE3	22924	microtubule-associated protein, RP/EB family, member 3	positive regulation of cyclin-dependent protein serine/threonine kinase activity	Biological process	17310996
STEAP4	79689	STEAP family member 4	oxidation-reduction process	Biological process	-
ITGB1	3688	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	tissue homeostasis	Biological process	-
NPR3	4883	natriuretic peptide receptor 3	skeletal system development	Biological process	-
YAP1	10413	Yes-associated protein 1	cellular response to gamma radiation	Biological process	18280240
WNT3	7473	wingless-type MMTV integration site family, member 3	embryonic forelimb morphogenesis	Biological process	-
RPH3A	22895	rabphilin 3A	calcium ion-dependent exocytosis of neurotransmitter	Biological process	-
SQSTM1	8878	sequestosome 1	autophagosome	Cellular component	17580304
CBX2	84733	chromobox homolog 2	protein sumoylation	Biological process	-
CALCA	796	calcitonin-related polypeptide alpha	cytosolic calcium ion homeostasis	Biological process	9685362
FCGR2C	9103	Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)	protein binding	Molecular function	17474147
TNFSF10	8743	tumor necrosis factor (ligand) superfamily, member 10	extracellular space	Cellular component	-
PRMT3	10196	protein arginine methyltransferase 3	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine	Biological process	-
Sep-07	989	septin 7	synapse	Cellular component	-
SLC9A3R1	9368	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1	dopamine receptor binding	Molecular function	-
IL9R	3581	interleukin 9 receptor	integral component of plasma membrane	Cellular component	1376929
ORM2	5005	orosomucoid 2	acute-phase response	Biological process	-
EVI5	7813	ecotropic viral integration site 5	cell proliferation	Biological process	9618176
KDR	3791	kinase insert domain receptor	positive regulation of endothelial cell proliferation	Biological process	10022831
NMD3	51068	NMD3 ribosome export adaptor	ribosomal large subunit export from nucleus	Biological process	12773398
TNPO1	3842	transportin 1	cytoplasm	Cellular component	9144189
AMD1	262	adenosylmethionine decarboxylase 1	cellular nitrogen compound metabolic process	Biological process	-
CASP9	842	caspase 9, apoptosis-related cysteine peptidase	response to estradiol	Biological process	-
SRSF6	6431	serine/arginine-rich splicing factor 6	positive regulation of epithelial cell proliferation involved in lung morphogenesis	Biological process	23132731
FASLG	356	Fas ligand (TNF superfamily, member 6)	inflammatory cell apoptotic process	Biological process	-
TRIM27	5987	tripartite motif containing 27	spermatogenesis	Biological process	3380101
NLRC5	84166	NLR family, CARD domain containing 5	regulation of kinase activity	Biological process	20434986
SRF	6722	serum response factor (c-fos serum response element-binding transcription factor)	positive regulation of transcription via serum response element binding	Biological process	3203386
ASUN	55726	asunder spermatogenesis regulator	centrosome localization	Biological process	23097494
SLC34A1	6569	solute carrier family 34 (type II sodium/phosphate cotransporter), member 1	response to magnesium ion	Biological process	-
KCNJ2	3759	potassium channel, inwardly rectifying subfamily J, member 2	phosphatidylinositol-4,5-bisphosphate binding	Molecular function	12086641
CEACAM8	1088	carcinoembryonic antigen-related cell adhesion molecule 8	extracellular exosome	Cellular component	23533145
LTV1	84946	LTV1 ribosome biogenesis factor	protein binding	Molecular function	25416956
APOA1	335	apolipoprotein A-I	reverse cholesterol transport	Biological process	15464323
SMAD7	4092	SMAD family member 7	BMP signaling pathway	Biological process	-
PROM1	8842	prominin 1	cell surface	Cellular component	16809613
SAP130	79595	Sin3A-associated protein, 130kDa	gene expression	Biological process	-
IL1R1	3554	interleukin 1 receptor, type I	transmembrane signaling receptor activity	Molecular function	2530587
DNAJC5	80331	DnaJ (Hsp40) homolog, subfamily C, member 5	negative regulation of neuron apoptotic process	Biological process	-
NSMCE1	197370	non-SMC element 1 homolog (S. cerevisiae)	chromosome, telomeric region	Cellular component	-
F10	2159	coagulation factor X	blood coagulation, intrinsic pathway	Biological process	-
KCNA1	3736	potassium channel, voltage gated shaker related subfamily A, member 1	synaptic transmission	Biological process	-
NAE1	8883	NEDD8 activating enzyme E1 subunit 1	plasma membrane	Cellular component	-
RPA3	6119	replication protein A3, 14kDa	DNA recombinase assembly	Biological process	-
THBS1	7057	thrombospondin 1	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	Biological process	18726995
FAM162A	26355	family with sequence similarity 162, member A	protein binding	Molecular function	15082785
MIS12	79003	MIS12 kinetochore complex component	small GTPase mediated signal transduction	Biological process	-
RBMS1	5937	RNA binding motif, single stranded interacting protein 1	DNA replication	Biological process	7838710
COPB2	9276	coatomer protein complex, subunit beta 2 (beta prime)	retrograde vesicle-mediated transport, Golgi to ER	Biological process	11030615
TBL2	26608	transducin (beta)-like 2	phosphoprotein binding	Molecular function	25393282
CDCA5	113130	cell division cycle associated 5	mitotic metaphase plate congression	Biological process	15837422
FAM215A	23591	family with sequence similarity 215, member A (non-protein coding)	molecular_function	Molecular function	-
DAG1	1605	dystroglycan 1 (dystrophin-associated glycoprotein 1)	membrane protein ectodomain proteolysis	Biological process	19946898
APOA4	337	apolipoprotein A-IV	regulation of intestinal cholesterol absorption	Biological process	-
SLC26A7	115111	solute carrier family 26 (anion exchanger), member 7	bicarbonate transport	Biological process	12736153
KCNMB2	10242	potassium channel subfamily M regulatory beta subunit 2	ion channel inhibitor activity	Molecular function	10097176
NUP98	4928	nucleoporin 98kDa	cytosol	Cellular component	-
HIST1H3J	8356	histone cluster 1, H3j	membrane	Cellular component	19946888
PSMB6	5694	proteasome (prosome, macropain) subunit, beta type, 6	regulation of cellular amino acid metabolic process	Biological process	-
PKD2	5311	polycystic kidney disease 2 (autosomal dominant)	ciliary membrane	Cellular component	-
ODF3	113746	outer dense fiber of sperm tails 3	multicellular organismal development	Biological process	-
KCNK16	83795	potassium channel, two pore domain subfamily K, member 16	potassium ion transmembrane transport	Biological process	-
SPTBN2	6712	spectrin, beta, non-erythrocytic 2	actin binding	Molecular function	-
RARA	5914	retinoic acid receptor, alpha	transcription corepressor activity	Molecular function	20080953
EPHA5	2044	EPH receptor A5	peptidyl-tyrosine phosphorylation	Biological process	-
JAK2	3717	Janus kinase 2	movement of cell or subcellular component	Biological process	9670957
TNKS2	80351	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2	NAD+ ADP-ribosyltransferase activity	Molecular function	-
XKR3	150165	XK, Kell blood group complex subunit-related family, member 3	integral component of membrane	Cellular component	-
BMP4	652	bone morphogenetic protein 4	renal system development	Biological process	17850284
NR2F6	2063	nuclear receptor subfamily 2, group F, member 6	neuron development	Biological process	-
CACNA1D	776	calcium channel, voltage-dependent, L type, alpha 1D subunit	membrane depolarization during cardiac muscle cell action potential	Biological process	21859974
CRYBA4	1413	crystallin, beta A4	protein binding	Molecular function	25416956
SP1	6667	Sp1 transcription factor	liver development	Biological process	-
EGLN2	112398	egl-9 family hypoxia-inducible factor 2	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors	Molecular function	11595184
TERT	7015	telomerase reverse transcriptase	telomere maintenance via telomerase	Biological process	-
PIP5K1C	23396	phosphatidylinositol-4-phosphate 5-kinase, type I, gamma	1-phosphatidylinositol-4-phosphate 5-kinase activity	Molecular function	-
IL1B	3553	interleukin 1, beta	positive regulation of JNK cascade	Biological process	-
USH1G	124590	Usher syndrome 1G (autosomal recessive)	inner ear morphogenesis	Biological process	-
LMAN1	3998	lectin, mannose-binding, 1	membrane	Cellular component	19946888
ALOX15	246	arachidonate 15-lipoxygenase	hepoxilin-epoxide hydrolase activity	Molecular function	-
IGF1	3479	insulin-like growth factor 1 (somatomedin C)	positive regulation of smooth muscle cell migration	Biological process	10766744
USP21	27005	ubiquitin specific peptidase 21	ubiquitin-specific protease activity	Molecular function	10799498
CLCN1	1180	chloride channel, voltage-sensitive 1	chloride transmembrane transport	Biological process	1379744
C5AR2	27202	complement component 5a receptor 2	apical part of cell	Cellular component	22496247
SLC12A6	9990	solute carrier family 12 (potassium/chloride transporter), member 6	potassium ion transport	Biological process	-
YTHDC1	91746	YTH domain containing 1	nuclear body	Cellular component	-
EIF4EBP1	1978	eukaryotic translation initiation factor 4E binding protein 1	protein complex	Cellular component	-
SKA1	220134	spindle and kinetochore associated complex subunit 1	mitotic cell cycle	Biological process	-
SLC2A6	11182	solute carrier family 2 (facilitated glucose transporter), member 6	integral component of plasma membrane	Cellular component	-
SOD1	6647	superoxide dismutase 1, soluble	neuronal cell body	Cellular component	17324120
HN1L	90861	hematological and neurological expressed 1-like	plasma membrane	Cellular component	-
COL11A2	1302	collagen, type XI, alpha 2	metal ion binding	Molecular function	-
AZGP1	563	alpha-2-glycoprotein 1, zinc-binding	protein binding	Molecular function	16237761
MAN1A1	4121	mannosidase, alpha, class 1A, member 1	protein N-linked glycosylation via asparagine	Biological process	-
KCNK10	54207	potassium channel, two pore domain subfamily K, member 10	plasma membrane	Cellular component	-
PHOSPHO2	493911	phosphatase, orphan 2	protein binding	Molecular function	25416956
CDC42EP1	11135	CDC42 effector protein (Rho GTPase binding) 1	protein binding	Molecular function	16189514
FPGS	2356	folylpolyglutamate synthase	tetrahydrofolylpolyglutamate synthase activity	Molecular function	-
MAP3K2	10746	mitogen-activated protein kinase kinase kinase 2	positive regulation of transcription, DNA-templated	Biological process	14515274
IL20RB	53833	interleukin 20 receptor beta	cytokine-mediated signaling pathway	Biological process	-
KRTAP10-5	386680	keratin associated protein 10-5	protein binding	Molecular function	25416956
IL1R1	3554	interleukin 1 receptor, type I	cell surface receptor signaling pathway	Biological process	1833184
HIPK1	204851	homeodomain interacting protein kinase 1	lens induction in camera-type eye	Biological process	-
ELOVL7	79993	ELOVL fatty acid elongase 7	transferase activity	Molecular function	-
TNF	7124	tumor necrosis factor	positive regulation of protein complex assembly	Biological process	12813029
AP1S2	8905	adaptor-related protein complex 1, sigma 2 subunit	cytoplasmic vesicle membrane	Cellular component	-
NCAPD2	9918	non-SMC condensin I complex, subunit D2	mitotic cell cycle	Biological process	-
VASP	7408	vasodilator-stimulated phosphoprotein	extracellular exosome	Cellular component	19056867
SMR3A	26952	submaxillary gland androgen regulated protein 3A	extracellular region	Cellular component	-
TLE3	7090	transducin-like enhancer of split 3	Wnt signaling pathway	Biological process	-
DLG5	9231	discs, large homolog 5 (Drosophila)	establishment or maintenance of epithelial cell apical/basal polarity	Biological process	-
HOXC10	3226	homeobox C10	skeletal system development	Biological process	-
TRIM22	10346	tripartite motif containing 22	negative regulation of nucleic acid-templated transcription	Biological process	7797467
FOXE1	2304	forkhead box E1	sequence-specific DNA binding transcription factor activity	Molecular function	9697705
SLC24A1	9187	solute carrier family 24 (sodium/potassium/calcium exchanger), member 1	integral component of plasma membrane	Cellular component	9478004
CASP4	837	caspase 4, apoptosis-related cysteine peptidase	regulation of inflammatory response	Biological process	-
GEMIN4	50628	gem (nuclear organelle) associated protein 4	gene expression	Biological process	-
ACSL4	2182	acyl-CoA synthetase long-chain family member 4	response to nutrient	Biological process	-
FUT1	2523	fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)	Golgi apparatus	Cellular component	11698403
FBXW7	55294	F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase	positive regulation of ERK1 and ERK2 cascade	Biological process	20208556
P2RY1	5028	purinergic receptor P2Y, G-protein coupled, 1	plasma membrane	Cellular component	-
HAGHL	84264	hydroxyacylglutathione hydrolase-like	metabolic process	Biological process	-
LHX5	64211	LIM homeobox 5	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation	Biological process	-
SPIRE2	84501	spire-type actin nucleation factor 2	actin nucleation	Biological process	-
CALM1	801	calmodulin 1 (phosphorylase kinase, delta)	protein domain specific binding	Molecular function	11984006
NOX1	27035	NADPH oxidase 1	regulation of ion transmembrane transport	Biological process	-
GABRA5	2558	gamma-aminobutyric acid (GABA) A receptor, alpha 5	synaptic transmission	Biological process	-
DUX1	26584	double homeobox 1	nucleus	Cellular component	-
ADCY6	112	adenylate cyclase 6	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway	Biological process	-
PNPLA2	57104	patatin-like phospholipase domain containing 2	acylglycerol acyl-chain remodeling	Biological process	-
PRRT2	112476	proline-rich transmembrane protein 2	cell junction	Cellular component	-
NUP85	79902	nucleoporin 85kDa	transmembrane transport	Biological process	-
CNGB1	1258	cyclic nucleotide gated channel beta 1	detection of light stimulus involved in visual perception	Biological process	15557452
MIXL1	83881	Mix paired-like homeobox	gastrulation	Biological process	-
STXBP1	6812	syntaxin binding protein 1	protein transport	Biological process	-
HOXD3	3232	homeobox D3	nucleoplasm	Cellular component	-
FBXO11	80204	F-box protein 11	ubiquitin-dependent protein catabolic process	Biological process	10531037
PPIL3	53938	peptidylprolyl isomerase (cyclophilin)-like 3	protein binding	Molecular function	16189514
EGR2	1959	early growth response 2	motor neuron axon guidance	Biological process	-
CLDN19	149461	claudin 19	identical protein binding	Molecular function	-
PEX26	55670	peroxisomal biogenesis factor 26	integral component of peroxisomal membrane	Cellular component	-
RNF207	388591	ring finger protein 207	regulation of heart looping	Biological process	-
CCNO	10309	cyclin O	cilium assembly	Biological process	24747639
ST3GAL6	10402	ST3 beta-galactoside alpha-2,3-sialyltransferase 6	keratan sulfate metabolic process	Biological process	-
EDN1	1906	endothelin 1	endothelin B receptor binding	Molecular function	10770212
ENDOU	8909	endonuclease, polyU-specific	female pregnancy	Biological process	2350438
METTL20	254013	methyltransferase like 20	methyltransferase activity	Molecular function	-
TDP2	51567	tyrosyl-DNA phosphodiesterase 2	nuclease activity	Molecular function	-
BTAF1	9044	BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa	DNA binding	Molecular function	-
SGK223	157285	homolog of rat pragma of Rnd2	ATP binding	Molecular function	-
OR4N5	390437	olfactory receptor, family 4, subfamily N, member 5	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
ANGPT4	51378	angiopoietin 4	blood coagulation	Biological process	-
TGFB1	7040	transforming growth factor, beta 1	response to glucose	Biological process	-
LANCL2	55915	LanC lantibiotic synthetase component C-like 2 (bacterial)	catalytic activity	Molecular function	-
DOCK1	1793	dedicator of cytokinesis 1	guanyl-nucleotide exchange factor activity	Molecular function	-
FGB	2244	fibrinogen beta chain	signal transduction	Biological process	-
EXOSC8	11340	exosome component 8	AU-rich element binding	Molecular function	16912217
CHP1	11261	calcineurin-like EF-hand protein 1	regulation of neuron death	Biological process	21085126
BTN3A1	11119	butyrophilin, subfamily 3, member A1	integral component of membrane	Cellular component	-
BARD1	580	BRCA1 associated RING domain 1	cell cycle arrest	Biological process	15632137
PNPT1	87178	polyribonucleotide nucleotidyltransferase 1	mitochondrion	Cellular component	-
BMI1	648	BMI1 proto-oncogene, polycomb ring finger	negative regulation of transcription from RNA polymerase II promoter	Biological process	19636380
TRIM59	286827	tripartite motif containing 59	protein binding	Molecular function	25416956
RPS27A	6233	ribosomal protein S27a	positive regulation of canonical Wnt signaling pathway	Biological process	-
AR	367	androgen receptor	cell proliferation	Biological process	10075738
SGTA	6449	small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha	cytoplasm	Cellular component	-
HOXD3	3232	homeobox D3	nucleus	Cellular component	12836255
HEG1	57493	heart development protein with EGF-like domains 1	regulation of body fluid levels	Biological process	-
UBA1	7317	ubiquitin-like modifier activating enzyme 1	heterochromatin	Cellular component	1376922
SPHK1	8877	sphingosine kinase 1	protein binding	Molecular function	12080051
ERAS	3266	ES cell expressed Ras	intracellular	Cellular component	-
IDH2	3418	isocitrate dehydrogenase 2 (NADP+), mitochondrial	cellular metabolic process	Biological process	-
ADCY9	115	adenylate cyclase 9	activation of protein kinase A activity	Biological process	-
CCBL2	56267	cysteine conjugate-beta lyase 2	2-oxoglutarate metabolic process	Biological process	-
ERBB2	2064	erb-b2 receptor tyrosine kinase 2	phosphatidylinositol-mediated signaling	Biological process	-
LDB1	8861	LIM domain binding 1	hair follicle development	Biological process	-
IKBKB	3551	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	B cell homeostasis	Biological process	-
SKP1	6500	S-phase kinase-associated protein 1	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological process	15103331
SMPD2	6610	sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)	sphingolipid metabolic process	Biological process	-
TDG	6996	thymine-DNA glycosylase	regulation of gene expression, epigenetic	Biological process	-
RPL36A	6173	ribosomal protein L36a	translation	Biological process	-
ADAMTSL3	57188	ADAMTS-like 3	protein binding	Molecular function	25416956
NDUFB5	4711	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa	nucleoplasm	Cellular component	-
CD34	947	CD34 molecule	positive regulation of gene expression	Biological process	17261663
ARID4B	51742	AT rich interactive domain 4B (RBP1-like)	histone H3-K9 trimethylation	Biological process	-
STX3	6809	syntaxin 3	neuron projection development	Biological process	-
RAB35	11021	RAB35, member RAS oncogene family	phosphatidylinositol-4,5-bisphosphate binding	Molecular function	16950109
GCLC	2729	glutamate-cysteine ligase, catalytic subunit	regulation of mitochondrial depolarization	Biological process	-
PLCE1	51196	phospholipase C, epsilon 1	plasma membrane	Cellular component	-
ATP2B4	493	ATPase, Ca++ transporting, plasma membrane 4	membrane	Cellular component	19946888
RAD51B	5890	RAD51 paralog B	DNA recombination	Biological process	9512535
GABRG1	2565	gamma-aminobutyric acid (GABA) A receptor, gamma 1	GABA-A receptor activity	Molecular function	-
CHD5	26038	chromodomain helicase DNA binding protein 5	DNA binding	Molecular function	-
IQGAP2	10788	IQ motif containing GTPase activating protein 2	signal transduction	Biological process	8756646
METAP1D	254042	methionyl aminopeptidase type 1D (mitochondrial)	protein initiator methionine removal	Biological process	-
STOX1	219736	storkhead box 1	cytoplasm	Cellular component	-
PSMC2	5701	proteasome (prosome, macropain) 26S subunit, ATPase, 2	positive regulation of canonical Wnt signaling pathway	Biological process	-
CHEK1	1111	checkpoint kinase 1	protein serine/threonine kinase activity	Molecular function	16963448
RPS7	6201	ribosomal protein S7	90S preribosome	Cellular component	-
CXCL12	6387	chemokine (C-X-C motif) ligand 12	positive regulation of myoblast fusion	Biological process	-
NOX4	50507	NADPH oxidase 4	positive regulation of MAP kinase activity	Biological process	-
TDG	6996	thymine-DNA glycosylase	protein domain specific binding	Molecular function	-
ITGB8	3696	integrin, beta 8	ganglioside metabolic process	Biological process	-
NPAP1	23742	nuclear pore associated protein 1	extracellular exosome	Cellular component	23376485
NR0B2	8431	nuclear receptor subfamily 0, group B, member 2	protein complex	Cellular component	-
GINS4	84296	GINS complex subunit 4 (Sld5 homolog)	DNA replication initiation	Biological process	-
ZBTB45	84878	zinc finger and BTB domain containing 45	nucleus	Cellular component	-
VPS13D	55187	vacuolar protein sorting 13 homolog D (S. cerevisiae)	protein targeting to vacuole	Biological process	-
HNRNPU	3192	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	circadian regulation of gene expression	Biological process	-
SNRNP40	9410	small nuclear ribonucleoprotein 40kDa (U5)	catalytic step 2 spliceosome	Cellular component	11991638
CSE1L	1434	CSE1 chromosome segregation 1-like (yeast)	nucleoplasm	Cellular component	-
ELF2	1998	E74-like factor 2 (ets domain transcription factor)	protein binding	Molecular function	14970218
FAM185A	222234	family with sequence similarity 185, member A	cytoplasm	Cellular component	-
ACIN1	22985	apoptotic chromatin condensation inducer 1	plasma membrane	Cellular component	-
SLC24A2	25769	solute carrier family 24 (sodium/potassium/calcium exchanger), member 2	calcium, potassium:sodium antiporter activity	Molecular function	18166528
AGXT	189	alanine-glyoxylate aminotransferase	amino acid binding	Molecular function	18492492
PTCH1	5727	patched 1	endocytic vesicle membrane	Cellular component	-
HVCN1	84329	hydrogen voltage gated channel 1	cellular response to zinc ion	Biological process	22020278
TFR2	7036	transferrin receptor 2	cytoplasm	Cellular component	-
LHCGR	3973	luteinizing hormone/choriogonadotropin receptor	activation of adenylate cyclase activity	Biological process	-
EOMES	8320	eomesodermin	sequence-specific DNA binding transcription factor activity	Molecular function	-
IFIH1	64135	interferon induced with helicase C domain 1	regulation of type III interferon production	Biological process	21616437
F13A1	2162	coagulation factor XIII, A1 polypeptide	platelet degranulation	Biological process	-
PCDHGB1	56104	protocadherin gamma subfamily B, 1	integral component of membrane	Cellular component	-
PRDM15	63977	PR domain containing 15	transcription, DNA-templated	Biological process	-
SHANK3	85358	SH3 and multiple ankyrin repeat domains 3	scaffold protein binding	Molecular function	-
SCO1	6341	SCO1 cytochrome c oxidase assembly protein	respiratory chain complex IV assembly	Biological process	-
MOSPD1	56180	motile sperm domain containing 1	perinuclear region of cytoplasm	Cellular component	-
RRP7A	27341	ribosomal RNA processing 7 homolog A (S. cerevisiae)	UTP-C complex	Cellular component	-
PPM1A	5494	protein phosphatase, Mg2+/Mn2+ dependent, 1A	voltage-gated calcium channel complex	Cellular component	-
NGEF	25791	neuronal guanine nucleotide exchange factor	guanyl-nucleotide exchange factor activity	Molecular function	-
ACTC1	70	actin, alpha, cardiac muscle 1	actin filament-based movement	Biological process	16611632
ABI1	10006	abl-interactor 1	transmembrane receptor protein tyrosine kinase signaling pathway	Biological process	9010225
MYOD1	4654	myogenic differentiation 1	skeletal muscle cell differentiation	Biological process	-
OR4F3	26683	olfactory receptor, family 4, subfamily F, member 3	integral component of membrane	Cellular component	-
DPRX	503834	divergent-paired related homeobox	regulation of transcription, DNA-templated	Biological process	-
CXCL2	2920	chemokine (C-X-C motif) ligand 2	chemokine-mediated signaling pathway	Biological process	-
ISCU	23479	iron-sulfur cluster assembly enzyme	mitochondrion	Cellular component	11060020
BPTF	2186	bromodomain PHD finger transcription factor	nucleus	Cellular component	10403843
RRM2B	50484	ribonucleotide reductase M2 B (TP53 inducible)	protein binding	Molecular function	25416956
WASF1	8936	WAS protein family, member 1	actin binding	Molecular function	-
KIT	3815	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	actin cytoskeleton reorganization	Biological process	1721869
FHOD1	29109	formin homology 2 domain containing 1	membrane	Cellular component	19946888
CHIA	27159	chitinase, acidic	response to fungus	Biological process	11085997
PHTF1	10745	putative homeodomain transcription factor 1	endoplasmic reticulum	Cellular component	-
LHX4	89884	LIM homeobox 4	sequence-specific DNA binding	Molecular function	-
OXCT1	5019	3-oxoacid CoA transferase 1	adipose tissue development	Biological process	-
APIP	51074	APAF1 interacting protein	small molecule metabolic process	Biological process	-
LIPC	3990	lipase, hepatic	high-density lipoprotein particle	Cellular component	-
HSP90AA1	3320	heat shock protein 90kDa alpha (cytosolic), class A member 1	protein binding	Molecular function	12176997
HENMT1	113802	HEN1 methyltransferase homolog 1 (Arabidopsis)	RNA methylation	Biological process	-
NPPC	4880	natriuretic peptide C	response to drug	Biological process	-
UGT1A4	54657	UDP glucuronosyltransferase 1 family, polypeptide A4	xenobiotic glucuronidation	Biological process	-
TIMP1	7076	TIMP metallopeptidase inhibitor 1	response to hormone	Biological process	-
CMC2	56942	C-x(9)-C motif containing 2	mitochondrion	Cellular component	20220131
SFRP1	6422	secreted frizzled-related protein 1	Wnt signaling pathway involved in somitogenesis	Biological process	-
DCN	1634	decorin	extracellular matrix	Cellular component	22261194
CUBN	8029	cubilin (intrinsic factor-cobalamin receptor)	lysosomal lumen	Cellular component	-
ARL2	402	ADP-ribosylation factor-like 2	regulation of insulin secretion	Biological process	-
OLFML2A	169611	olfactomedin-like 2A	protein homodimerization activity	Molecular function	-
GJB2	2706	gap junction protein, beta 2, 26kDa	transmembrane transport	Biological process	-
PNPLA1	285848	patatin-like phospholipase domain containing 1	lipid catabolic process	Biological process	-
ABCA7	10347	ATP-binding cassette, sub-family A (ABC1), member 7	ATPase activity, coupled to transmembrane movement of substances	Molecular function	-
CACNA1B	774	calcium channel, voltage-dependent, N type, alpha 1B subunit	regulation of calcium ion transport	Biological process	-
ITPR1	3708	inositol 1,4,5-trisphosphate receptor, type 1	membrane	Cellular component	19946888
PGLYRP2	114770	peptidoglycan recognition protein 2	regulation of inflammatory response	Biological process	-
DDX60	55601	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	innate immune response	Biological process	-
CHMP2A	27243	charged multivesicular body protein 2A	late endosome membrane	Cellular component	-
NEDD4	4734	neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase	transmission of virus	Biological process	15126635
IGFBP4	3487	insulin-like growth factor binding protein 4	cellular protein metabolic process	Biological process	-
GSTA1	2938	glutathione S-transferase alpha 1	metabolic process	Biological process	3800996
ARHGAP35	2909	Rho GTPase activating protein 35	transcription corepressor activity	Molecular function	1894621
MRPS24	64951	mitochondrial ribosomal protein S24	translation	Biological process	-
ADCY5	111	adenylate cyclase 5	cAMP biosynthetic process	Biological process	-
GCLC	2729	glutamate-cysteine ligase, catalytic subunit	cysteine metabolic process	Biological process	2294991
PREX1	57580	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	G-protein coupled receptor signaling pathway	Biological process	-
NCAPD2	9918	non-SMC condensin I complex, subunit D2	cytoplasm	Cellular component	10958694
DSCR4	10281	Down syndrome critical region 4	biological_process	Biological process	-
CSN1S1	1446	casein alpha s1	extracellular space	Cellular component	16502470
PMP22	5376	peripheral myelin protein 22	bicellular tight junction	Cellular component	-
HK3	3101	hexokinase 3 (white cell)	small molecule metabolic process	Biological process	-
TAPBPL	55080	TAP binding protein-like	integral component of membrane	Cellular component	-
SMC6	79677	structural maintenance of chromosomes 6	chromosome, telomeric region	Cellular component	17589526
SNTB1	6641	syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)	protein binding	Molecular function	12477932
SERPINB2	5055	serpin peptidase inhibitor, clade B (ovalbumin), member 2	plasma membrane	Cellular component	-
FGF10	2255	fibroblast growth factor 10	urothelial cell proliferation	Biological process	11923311
OSBPL1A	114876	oxysterol binding protein-like 1A	vesicle-mediated transport	Biological process	11279184
UTP11L	51118	UTP11-like, U3 small nucleolar ribonucleoprotein (yeast)	rRNA processing	Biological process	-
ACOT11	26027	acyl-CoA thioesterase 11	carboxylic ester hydrolase activity	Molecular function	-
VPS4B	9525	vacuolar protein sorting 4 homolog B (S. cerevisiae)	positive regulation of G2/M transition of mitotic cell cycle	Biological process	20616062
ABL1	25	ABL proto-oncogene 1, non-receptor tyrosine kinase	cell migration	Biological process	-
HNRNPA1	3178	heterogeneous nuclear ribonucleoprotein A1	mRNA splicing, via spliceosome	Biological process	-
TBC1D30	23329	TBC1 domain family, member 30	ciliary basal body	Cellular component	17646400
TWIST2	117581	twist family bHLH transcription factor 2	positive regulation of keratinocyte proliferation	Biological process	-
PLAT	5327	plasminogen activator, tissue	extracellular space	Cellular component	-
CPSF6	11052	cleavage and polyadenylation specific factor 6, 68kDa	nucleus	Cellular component	20695905
CYP2C9	1559	cytochrome P450, family 2, subfamily C, polypeptide 9	drug metabolic process	Biological process	21127708
EXOC7	23265	exocyst complex component 7	microtubule organizing center	Cellular component	18000879
CCT4	10575	chaperonin containing TCP1, subunit 4 (delta)	protein binding	Molecular function	24846140
HSPA1B	3304	heat shock 70kDa protein 1B	ATP binding	Molecular function	23921388
VCAN	1462	versican	membrane	Cellular component	16210410
GNA14	9630	guanine nucleotide binding protein (G protein), alpha 14	GTPase activity	Molecular function	-
Mar-09	92979	membrane-associated ring finger (C3HC4) 9	lysosomal membrane	Cellular component	-
IRF4	3662	interferon regulatory factor 4	positive regulation of transcription from RNA polymerase II promoter	Biological process	12374808
MKL2	57496	MKL/myocardin-like 2	smooth muscle cell differentiation	Biological process	-
RPP40	10799	ribonuclease P/MRP 40kDa subunit	RNA phosphodiester bond hydrolysis	Biological process	9630247
PRELID1	27166	PRELI domain containing 1	regulation of T cell differentiation	Biological process	18945965
TRMT12	55039	tRNA methyltransferase 12 homolog (S. cerevisiae)	transferase activity	Molecular function	-
KDM3B	51780	lysine (K)-specific demethylase 3B	chromatin organization	Biological process	-
ERVW-1	30816	endogenous retrovirus group W, member 1	plasma membrane	Cellular component	-
TRAF6	7189	TNF receptor-associated factor 6, E3 ubiquitin protein ligase	antigen processing and presentation of exogenous peptide antigen via MHC class II	Biological process	-
DLAT	1737	dihydrolipoamide S-acetyltransferase	pyruvate metabolic process	Biological process	-
PARK2	5071	parkin RBR E3 ubiquitin protein ligase	cullin family protein binding	Molecular function	12628165
NTRK1	4914	neurotrophic tyrosine kinase, receptor, type 1	positive regulation of ERK1 and ERK2 cascade	Biological process	15488758
ATP6V0D1	9114	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1	early endosome	Cellular component	-
S100A12	6283	S100 calcium binding protein A12	zinc ion binding	Molecular function	11522286
TIGAR	57103	TP53 induced glycolysis regulatory phosphatase	gene expression	Biological process	-
CNP	1267	2',3'-cyclic nucleotide 3' phosphodiesterase	nucleus	Cellular component	-
TP53	7157	tumor protein p53	positive regulation of histone deacetylation	Biological process	-
PPIF	10105	peptidylprolyl isomerase F	cyclosporin A binding	Molecular function	-
HEPACAM	220296	hepatic and glial cell adhesion molecule	axon	Cellular component	21419380
CYP2A6	1548	cytochrome P450, family 2, subfamily A, polypeptide 6	epoxygenase P450 pathway	Biological process	-
BCL9L	283149	B-cell CLL/lymphoma 9-like	transcription, DNA-templated	Biological process	-
OR5AU1	390445	olfactory receptor, family 5, subfamily AU, member 1	sensory perception of smell	Biological process	-
ZFYVE26	23503	zinc finger, FYVE domain containing 26	metal ion binding	Molecular function	-
RAB2A	5862	RAB2A, member RAS oncogene family	endoplasmic reticulum-Golgi intermediate compartment membrane	Cellular component	-
EIF2S1	1965	eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa	positive regulation of defense response to virus by host	Biological process	22020285
CNOT1	23019	CCR4-NOT transcription complex, subunit 1	transcription, DNA-templated	Biological process	-
GAD1	2571	glutamate decarboxylase 1 (brain, 67kDa)	neurotransmitter secretion	Biological process	-
GNS	2799	glucosamine (N-acetyl)-6-sulfatase	carbohydrate metabolic process	Biological process	-
POC1B	282809	POC1 centriolar protein B	cilium assembly	Biological process	20008567
MYO18A	399687	myosin XVIIIA	actomyosin	Cellular component	18854160
C2	717	complement component 2	complement activation	Biological process	-
MAP4K3	8491	mitogen-activated protein kinase kinase kinase kinase 3	intracellular	Cellular component	9275185
DCP1A	55802	decapping mRNA 1A	membrane	Cellular component	19946888
ZNF254	9534	zinc finger protein 254	negative regulation of transcription from RNA polymerase II promoter	Biological process	10585455
FAS	355	Fas cell surface death receptor	negative regulation of B cell activation	Biological process	-
CIITA	4261	class II, major histocompatibility complex, transactivator	positive regulation of transcription, DNA-templated	Biological process	19041327
ITGA3	3675	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	basolateral plasma membrane	Cellular component	-
OR11A1	26531	olfactory receptor, family 11, subfamily A, member 1	G-protein coupled receptor signaling pathway	Biological process	-
TFPT	29844	TCF3 (E2A) fusion partner (in childhood Leukemia)	regulation of transcription, DNA-templated	Biological process	-
COL18A1	80781	collagen, type XVIII, alpha 1	extracellular matrix disassembly	Biological process	-
RNF167	26001	ring finger protein 167	ligase activity	Molecular function	-
RAB32	10981	RAB32, member RAS oncogene family	BLOC-2 complex binding	Molecular function	22511774
IL17RB	55540	interleukin 17 receptor B	defense response	Biological process	10749887
CHGA	1113	chromogranin A	mast cell activation	Biological process	21214543
WFIKKN1	117166	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	extracellular region	Cellular component	-
ABHD17B	51104	abhydrolase domain containing 17B	membrane	Cellular component	19946888
GFAP	2670	glial fibrillary acidic protein	kinase binding	Molecular function	-
CCPG1	9236	cell cycle progression 1	positive regulation of cell cycle	Biological process	20957177
PTHLH	5744	parathyroid hormone-like hormone	positive regulation of cell proliferation	Biological process	-
MAP2K1	5604	mitogen-activated protein kinase kinase 1	negative regulation of homotypic cell-cell adhesion	Biological process	-
ZFP82	284406	ZFP82 zinc finger protein	regulation of transcription, DNA-templated	Biological process	-
NECAB1	64168	N-terminal EF-hand calcium binding protein 1	cytoplasm	Cellular component	-
DGKK	139189	diacylglycerol kinase, kappa	protein kinase C-activating G-protein coupled receptor signaling pathway	Biological process	-
MTIF2	4528	mitochondrial translational initiation factor 2	organelle organization	Biological process	-
SKA3	221150	spindle and kinetochore associated complex subunit 3	cell division	Biological process	-
RAB14	51552	RAB14, member RAS oncogene family	lysosomal membrane	Cellular component	17897319
RAB18	22931	RAB18, member RAS oncogene family	GTPase activity	Molecular function	10648831
DGUOK	1716	deoxyguanosine kinase	guanosine metabolic process	Biological process	8692979
CTSZ	1522	cathepsin Z	extracellular space	Cellular component	20551380
RASSF1	11186	Ras association (RalGDS/AF-6) domain family member 1	cytoplasm	Cellular component	-
FGF3	2248	fibroblast growth factor 3	cell-cell signaling	Biological process	2470007
RPL3	6122	ribosomal protein L3	nucleolus	Cellular component	-
DTNA	1837	dystrobrevin, alpha	striated muscle contraction	Biological process	10767327
IDO2	169355	indoleamine 2,3-dioxygenase 2	metal ion binding	Molecular function	-
IKZF3	22806	IKAROS family zinc finger 3 (Aiolos)	regulation of apoptotic process	Biological process	10369681
REST	5978	RE1-silencing transcription factor	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	10449787
TLR7	51284	toll-like receptor 7	double-stranded RNA binding	Molecular function	16111635
PTCH1	5727	patched 1	neural tube closure	Biological process	-
RAB7A	7879	RAB7A, member RAS oncogene family	epidermal growth factor catabolic process	Biological process	18272684
BCL2	596	B-cell CLL/lymphoma 2	female pregnancy	Biological process	11530860
NFASC	23114	neurofascin	paranodal junction	Cellular component	-
CPS1	1373	carbamoyl-phosphate synthase 1, mitochondrial	response to amine	Biological process	-
NR2F1	7025	nuclear receptor subfamily 2, group F, member 1	steroid hormone receptor activity	Molecular function	-
USE1	55850	unconventional SNARE in the ER 1 homolog (S. cerevisiae)	endoplasmic reticulum membrane	Cellular component	-
CALR3	125972	calreticulin 3	protein folding	Biological process	-
HMGA2	8091	high mobility group AT-hook 2	cell division	Biological process	-
FGG	2266	fibrinogen gamma chain	cell surface	Cellular component	6777381
RAB40AL	282808	RAB40A, member RAS oncogene family-like	protein ubiquitination	Biological process	-
INPP5J	27124	inositol polyphosphate-5-phosphatase J	negative regulation of microtubule polymerization	Biological process	-
FMN2	56776	formin 2	intracellular transport	Biological process	-
CD7	924	CD7 molecule	integral component of membrane	Cellular component	11485208
GHRH	2691	growth hormone releasing hormone	positive regulation of insulin-like growth factor receptor signaling pathway	Biological process	11773624
TBRG1	84897	transforming growth factor beta regulator 1	protein binding	Molecular function	17110379
Sep-07	989	septin 7	GTP binding	Molecular function	-
CLU	1191	clusterin	complement activation, classical pathway	Biological process	-
CLEC4M	10332	C-type lectin domain family 4, member M	modulation by virus of host morphology or physiology	Biological process	11337487
CRP	1401	C-reactive protein, pentraxin-related	filopodium	Cellular component	-
C2CD4A	145741	C2 calcium-dependent domain containing 4A	calcium-dependent phospholipid binding	Molecular function	-
TLR9	54106	toll-like receptor 9	positive regulation of interleukin-18 production	Biological process	-
ISL1	3670	ISL LIM homeobox 1	mitochondrion	Cellular component	-
USP30	84749	ubiquitin specific peptidase 30	mitochondrion degradation	Biological process	24896179
VPS4B	9525	vacuolar protein sorting 4 homolog B (S. cerevisiae)	microtubule-severing ATPase activity	Molecular function	-
ZNF316	100131017	zinc finger protein 316	transcription, DNA-templated	Biological process	-
APOBEC1	339	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	RNA processing	Biological process	7736571
HSP90B1	7184	heat shock protein 90kDa beta (Grp94), member 1	ER-associated ubiquitin-dependent protein catabolic process	Biological process	18264092
IRS2	8660	insulin receptor substrate 2	protein domain specific binding	Molecular function	-
NFIX	4784	nuclear factor I/X (CCAAT-binding transcription factor)	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity	Molecular function	7937100
CAV3	859	caveolin 3	negative regulation of calcium ion transport	Biological process	21084288
GLB1L2	89944	galactosidase, beta 1-like 2	carbohydrate metabolic process	Biological process	-
MYO5A	4644	myosin VA (heavy chain 12, myoxin)	neuronal cell body	Cellular component	-
ERBB3	2065	erb-b2 receptor tyrosine kinase 3	neuron apoptotic process	Biological process	17701904
NME9	347736	NME/NM23 family member 9	UTP biosynthetic process	Biological process	-
EXTL2	2135	exostosin-like glycosyltransferase 2	N-acetylglucosamine metabolic process	Biological process	10318803
GPR150	285601	G protein-coupled receptor 150	plasma membrane	Cellular component	-
WNT3A	89780	wingless-type MMTV integration site family, member 3A	negative regulation of neurogenesis	Biological process	-
TFAP4	7023	transcription factor AP-4 (activating enhancer binding protein 4)	protein homodimerization activity	Molecular function	2123466
MLEC	9761	malectin	endoplasmic reticulum	Cellular component	-
PDCD6	10016	programmed cell death 6	calcium-dependent protein binding	Molecular function	16957052
NPR3	4883	natriuretic peptide receptor 3	natriuretic peptide receptor activity	Molecular function	1660465
PDE8A	5151	phosphodiesterase 8A	3',5'-cyclic-AMP phosphodiesterase activity	Molecular function	-
GBA3	57733	glucosidase, beta, acid 3 (gene/pseudogene)	glycosylceramide catabolic process	Biological process	17595169
LCK	3932	LCK proto-oncogene, Src family tyrosine kinase	activation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	-
NOG	9241	noggin	skeletal system development	Biological process	10080184
LOC400927-CSNK1E	102800317	LOC400927-CSNK1E readthrough	Wnt signaling pathway	Biological process	-
RAB3IP	117177	RAB3A interacting protein	ciliary basal body	Cellular component	17574030
SIX2	10736	SIX homeobox 2	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
ATP2A1	487	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	endoplasmic reticulum membrane	Cellular component	-
RUNX1	861	runt-related transcription factor 1	core promoter binding	Molecular function	17377532
MMP16	4325	matrix metallopeptidase 16 (membrane-inserted)	chondrocyte proliferation	Biological process	-
FGF8	2253	fibroblast growth factor 8 (androgen-induced)	branching involved in ureteric bud morphogenesis	Biological process	-
KIF22	3835	kinesin family member 22	focal adhesion	Cellular component	-
IL12RB1	3594	interleukin 12 receptor, beta 1	positive regulation of activated T cell proliferation	Biological process	11114383
STAT5B	6777	signal transducer and activator of transcription 5B	positive regulation of B cell differentiation	Biological process	-
RNF8	9025	ring finger protein 8, E3 ubiquitin protein ligase	protein homodimerization activity	Molecular function	22980979
GHRHR	2692	growth hormone releasing hormone receptor	response to insulin	Biological process	17356054
SLC22A3	6581	solute carrier family 22 (organic cation transporter), member 3	protein binding	Molecular function	17474147
TCF21	6943	transcription factor 21	negative regulation of transcription from RNA polymerase II promoter	Biological process	12493738
C17orf59	54785	chromosome 17 open reading frame 59	protein binding	Molecular function	25416956
UBA52	7311	ubiquitin A-52 residue ribosomal protein fusion product 1	apoptotic signaling pathway	Biological process	-
PTPN1	5770	protein tyrosine phosphatase, non-receptor type 1	negative regulation of ERK1 and ERK2 cascade	Biological process	-
NR1I2	8856	nuclear receptor subfamily 1, group I, member 2	positive regulation of transcription from RNA polymerase II promoter	Biological process	11114890
TDP2	51567	tyrosyl-DNA phosphodiesterase 2	transcription corepressor activity	Molecular function	10764746
LUC7L2	51631	LUC7-like 2 (S. cerevisiae)	poly(A) RNA binding	Molecular function	22681889
TREM2	54209	triggering receptor expressed on myeloid cells 2	lipoteichoic acid binding	Molecular function	-
HOXA2	3199	homeobox A2	brain segmentation	Biological process	-
NR1H2	7376	nuclear receptor subfamily 1, group H, member 2	steroid hormone mediated signaling pathway	Biological process	-
PIP5K1A	8394	phosphatidylinositol-4-phosphate 5-kinase, type I, alpha	1-phosphatidylinositol-4-phosphate 5-kinase activity	Molecular function	18305108
KRT74	121391	keratin 74, type II	intermediate filament cytoskeleton organization	Biological process	20346438
PARVA	55742	parvin, alpha	actin-mediated cell contraction	Biological process	-
GPR143	4935	G protein-coupled receptor 143	visual perception	Biological process	7647783
SGPL1	8879	sphingosine-1-phosphate lyase 1	skeletal system morphogenesis	Biological process	-
ADRA2A	150	adrenoceptor alpha 2A	phospholipase C-activating adrenergic receptor signaling pathway	Biological process	10948191
PAIP2	51247	poly(A) binding protein interacting protein 2	negative regulation of translational initiation	Biological process	11172725
TDRD12	91646	tudor domain containing 12	DNA methylation involved in gamete generation	Biological process	-
RECQL5	9400	RecQ protein-like 5	nucleic acid binding	Molecular function	-
PTPRR	5801	protein tyrosine phosphatase, receptor type, R	protein dephosphorylation	Biological process	7836467
FIGNL1	63979	fidgetin-like 1	magnesium ion binding	Molecular function	-
HIST1H4K	8362	histone cluster 1, H4k	DNA binding	Molecular function	3035717
USP41	373856	ubiquitin specific peptidase 41	regulation of proteasomal protein catabolic process	Biological process	-
GRM6	2916	glutamate receptor, metabotropic 6	glutamate receptor activity	Molecular function	9215706
CSHL1	1444	chorionic somatomammotropin hormone-like 1	metal ion binding	Molecular function	-
BARHL2	343472	BarH-like homeobox 2	cytoplasm	Cellular component	-
PPCS	79717	phosphopantothenoylcysteine synthetase	cytosol	Cellular component	-
ATF2	1386	activating transcription factor 2	regulation of sequence-specific DNA binding transcription factor activity	Biological process	-
RNF141	50862	ring finger protein 141	zinc ion binding	Molecular function	-
TAF12	6883	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa	chromatin organization	Biological process	-
SLC6A19	340024	solute carrier family 6 (neutral amino acid transporter), member 19	extracellular exosome	Cellular component	19056867
PLAUR	5329	plasminogen activator, urokinase receptor	chemotaxis	Biological process	10749881
ITIH6	347365	inter-alpha-trypsin inhibitor heavy chain family, member 6	negative regulation of endopeptidase activity	Biological process	-
FGFR2	2263	fibroblast growth factor receptor 2	extracellular region	Cellular component	-
IRS4	8471	insulin receptor substrate 4	regulation of lipid metabolic process	Biological process	-
ZNF35	7584	zinc finger protein 35	transcription, DNA-templated	Biological process	-
SOX9	6662	SRY (sex determining region Y)-box 9	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity	Molecular function	20484372
USP54	159195	ubiquitin specific peptidase 54	protein binding	Molecular function	16713569
POP4	10775	processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)	ribonuclease P activity	Molecular function	-
RAMP2	10266	receptor (G protein-coupled) activity modifying protein 2	vasculogenesis	Biological process	16964401
RAD21	5885	RAD21 homolog (S. pombe)	cell division	Biological process	-
ACOT13	55856	acyl-CoA thioesterase 13	extracellular exosome	Cellular component	23376485
UBE2D2	7322	ubiquitin-conjugating enzyme E2D 2	stimulatory C-type lectin receptor signaling pathway	Biological process	-
PARN	5073	poly(A)-specific ribonuclease	RNA phosphodiester bond hydrolysis, exonucleolytic	Biological process	-
TXN2	25828	thioredoxin 2	protein binding	Molecular function	25416956
SUFU	51684	suppressor of fused homolog (Drosophila)	nucleus	Cellular component	10806483
RPGRIP1	57096	retinitis pigmentosa GTPase regulator interacting protein 1	protein binding	Molecular function	21224891
CARS2	79587	cysteinyl-tRNA synthetase 2, mitochondrial (putative)	tRNA aminoacylation for protein translation	Biological process	-
PIK3C2G	5288	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma	phosphatidylinositol binding	Molecular function	-
TNRC6A	27327	trinucleotide repeat containing 6A	neurotrophin TRK receptor signaling pathway	Biological process	-
TLN1	7094	talin 1	cell-cell junction	Cellular component	15494027
RXFP2	122042	relaxin/insulin-like family peptide receptor 2	oocyte maturation	Biological process	-
MATN2	4147	matrilin 2	calcium ion binding	Molecular function	-
CACNA1S	779	calcium channel, voltage-dependent, L type, alpha 1S subunit	high voltage-gated calcium channel activity	Molecular function	9852570
ENPP3	5169	ectonucleotide pyrophosphatase/phosphodiesterase 3	inorganic diphosphate transport	Biological process	10513816
HSD17B14	51171	hydroxysteroid (17-beta) dehydrogenase 14	testosterone 17-beta-dehydrogenase (NADP+) activity	Molecular function	17067289
IDUA	3425	iduronidase, alpha-L-	L-iduronidase activity	Molecular function	24036510
SMARCA1	6594	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1	nucleus	Cellular component	14609955
ADCY8	114	adenylate cyclase 8 (brain)	water transport	Biological process	-
IGHV3-23	28442	immunoglobulin heavy variable 3-23	immune response	Biological process	6450418
FSHB	2488	follicle stimulating hormone, beta polypeptide	positive regulation of bone resorption	Biological process	-
CYB5R1	51706	cytochrome b5 reductase 1	mitochondrion	Cellular component	20833797
PARP3	10039	poly (ADP-ribose) polymerase family, member 3	catalytic activity	Molecular function	10338144
DLC1	10395	DLC1 Rho GTPase activating protein	positive regulation of GTPase activity	Biological process	17888903
NOTCH2	4853	notch 2	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
POU4F1	5457	POU class 4 homeobox 1	sensory system development	Biological process	-
AP1M2	10053	adaptor-related protein complex 1, mu 2 subunit	intracellular membrane-bounded organelle	Cellular component	-
SNAPC4	6621	small nuclear RNA activating complex, polypeptide 4, 190kDa	snRNA transcription from RNA polymerase III promoter	Biological process	9418884
PTPRD	5789	protein tyrosine phosphatase, receptor type, D	neuron differentiation	Biological process	-
DCLK1	9201	doublecortin-like kinase 1	protein phosphorylation	Biological process	-
AKR1C1	1645	aldo-keto reductase family 1, member C1	bile acid and bile salt transport	Biological process	8486699
C1orf116	79098	chromosome 1 open reading frame 116	extracellular exosome	Cellular component	19056867
FGD4	121512	FYVE, RhoGEF and PH domain containing 4	Rho guanyl-nucleotide exchange factor activity	Molecular function	-
ATP1A3	478	ATPase, Na+/K+ transporting, alpha 3 polypeptide	plasma membrane	Cellular component	-
RBMS1	5937	RNA binding motif, single stranded interacting protein 1	double-stranded DNA binding	Molecular function	7838710
ZC3H14	79882	zinc finger CCCH-type containing 14	nucleus	Cellular component	-
ACAN	176	aggrecan	cell adhesion	Biological process	-
LMOD2	442721	leiomodin 2 (cardiac)	actin filament organization	Biological process	-
CARD9	64170	caspase recruitment domain family, member 9	positive regulation of stress-activated MAPK cascade	Biological process	17187069
MAPRE1	22919	microtubule-associated protein, RP/EB family, member 1	protein localization to microtubule	Biological process	19632184
RFWD2	64326	ring finger and WD repeat domain 2, E3 ubiquitin protein ligase	ubiquitin protein ligase activity	Molecular function	19805145
SLC17A3	10786	solute carrier family 17 (organic anion transporter), member 3	sodium ion transmembrane transport	Biological process	-
SLC35B3	51000	solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3	carbohydrate metabolic process	Biological process	-
EGLN1	54583	egl-9 family hypoxia-inducible factor 1	labyrinthine layer development	Biological process	-
IL22	50616	interleukin 22	cytokine activity	Molecular function	-
LTBP2	4053	latent transforming growth factor beta binding protein 2	calcium ion binding	Molecular function	-
MRPL18	29074	mitochondrial ribosomal protein L18	mitochondrial translational initiation	Biological process	-
SRD5A3	79644	steroid 5 alpha-reductase 3	endoplasmic reticulum	Cellular component	20637498
RFX6	222546	regulatory factor X, 6	regulation of insulin secretion	Biological process	20148032
FUT9	10690	fucosyltransferase 9 (alpha (1,3) fucosyltransferase)	alpha-(1->3)-fucosyltransferase activity	Molecular function	11698403
FZD10	11211	frizzled class receptor 10	non-canonical Wnt signaling pathway via JNK cascade	Biological process	19137009
PAEP	5047	progestagen-associated endometrial protein	positive regulation of granulocyte macrophage colony-stimulating factor production	Biological process	19945098
HBEGF	1839	heparin-binding EGF-like growth factor	negative regulation of elastin biosynthetic process	Biological process	-
B3GALNT1	8706	beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)	integral component of membrane	Cellular component	-
SOCS6	9306	suppressor of cytokine signaling 6	proteasomal protein catabolic process	Biological process	20007709
HOOK1	51361	hook microtubule-tethering protein 1	protein binding	Molecular function	15471887
DMAP1	55929	DNA methyltransferase 1 associated protein 1	chromatin binding	Molecular function	-
INPP5K	51763	inositol polyphosphate-5-phosphatase K	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity	Molecular function	21712384
DLX5	1749	distal-less homeobox 5	HMG box domain binding	Molecular function	-
GSG1L	146395	GSG1-like	plasma membrane	Cellular component	-
GABRG3	2567	gamma-aminobutyric acid (GABA) A receptor, gamma 3	extracellular ligand-gated ion channel activity	Molecular function	-
CRY2	1408	cryptochrome circadian clock 2	ubiquitin binding	Molecular function	11889036
UBE2D2	7322	ubiquitin-conjugating enzyme E2D 2	extracellular exosome	Cellular component	23533145
TGFBR3	7049	transforming growth factor, beta receptor III	inhibin-betaglycan-ActRII complex	Cellular component	10746731
OR5I1	10798	olfactory receptor, family 5, subfamily I, member 1	G-protein coupled receptor activity	Molecular function	-
GNAI2	2771	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	membrane raft	Cellular component	-
ERF	2077	Ets2 repressor factor	negative regulation of transcription from RNA polymerase II promoter	Biological process	7588608
ENTPD1	953	ectonucleoside triphosphate diphosphohydrolase 1	platelet activation	Biological process	-
RNPS1	10921	RNA binding protein S1, serine-rich domain	RNA splicing	Biological process	-
IL27	246778	interleukin 27	interleukin-27 receptor binding	Molecular function	-
M6PR	4074	mannose-6-phosphate receptor (cation dependent)	endosome to lysosome transport	Biological process	10799489
VPS13A	23230	vacuolar protein sorting 13 homolog A (S. cerevisiae)	Golgi to endosome transport	Biological process	11381253
MGST1	4257	microsomal glutathione S-transferase 1	mitochondrial outer membrane	Cellular component	-
DUSP1	1843	dual specificity phosphatase 1	negative regulation of DNA biosynthetic process	Biological process	-
PRPF38B	55119	pre-mRNA processing factor 38B	RNA splicing	Biological process	-
RIC1	57589	RAB6A GEF complex partner 1	protein binding	Molecular function	23091056
PPAPDC1A	196051	phosphatidic acid phosphatase type 2 domain containing 1A	Fc-gamma receptor signaling pathway involved in phagocytosis	Biological process	-
DLG2	1740	discs, large homolog 2 (Drosophila)	plasma membrane	Cellular component	8755482
EPM2AIP1	9852	EPM2A (laforin) interacting protein 1	protein binding	Molecular function	25416956
ZFP90	146198	ZFP90 zinc finger protein	nucleus	Cellular component	-
MYO1E	4643	myosin IE	cytoplasm	Cellular component	-
AP1G2	8906	adaptor-related protein complex 1, gamma 2 subunit	Golgi-associated vesicle	Cellular component	9762922
ITGAM	3684	integrin, alpha M (complement component 3 receptor 3 subunit)	blood coagulation	Biological process	-
ATP13A2	23400	ATPase type 13A2	integral component of membrane	Cellular component	-
L1CAM	3897	L1 cell adhesion molecule	cell-cell adhesion mediated by integrin	Biological process	-
FKBP2	2286	FK506 binding protein 2, 13kDa	peptidyl-prolyl cis-trans isomerase activity	Molecular function	-
RPL37	6167	ribosomal protein L37	cellular protein metabolic process	Biological process	-
ATM	472	ATM serine/threonine kinase	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	Biological process	-
ICAM1	3383	intercellular adhesion molecule 1	cell surface	Cellular component	19581412
ST3GAL6	10402	ST3 beta-galactoside alpha-2,3-sialyltransferase 6	small molecule metabolic process	Biological process	-
RBM4B	83759	RNA binding motif protein 4B	circadian regulation of gene expression	Biological process	-
PSMA3	5684	proteasome (prosome, macropain) subunit, alpha type, 3	protein polyubiquitination	Biological process	-
WSB2	55884	WD repeat and SOCS box containing 2	protein ubiquitination	Biological process	-
ADCYAP1	116	adenylate cyclase activating polypeptide 1 (pituitary)	positive regulation of chemokine (C-C motif) ligand 5 production	Biological process	24696163
CTRB1	1504	chymotrypsinogen B1	extracellular region	Cellular component	-
KATNB1	10300	katanin p80 (WD repeat containing) subunit B 1	protein heterodimerization activity	Molecular function	10751153
HTR3B	9177	5-hydroxytryptamine (serotonin) receptor 3B, ionotropic	integral component of plasma membrane	Cellular component	-
ZNF791	163049	zinc finger protein 791	transcription, DNA-templated	Biological process	-
PILRA	29992	paired immunoglobin-like type 2 receptor alpha	viral process	Biological process	-
PARD3B	117583	par-3 family cell polarity regulator beta	membrane	Cellular component	-
KCNE2	9992	potassium channel, voltage gated subfamily E regulatory beta subunit 2	regulation of delayed rectifier potassium channel activity	Biological process	10219239
RPL26	6154	ribosomal protein L26	RNA binding	Molecular function	8479925
SLC5A6	8884	solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6	sodium ion transport	Biological process	-
MRPL42	28977	mitochondrial ribosomal protein L42	mitochondrial small ribosomal subunit	Cellular component	11279123
KCNA3	3738	potassium channel, voltage gated shaker related subfamily A, member 3	voltage-gated ion channel activity	Molecular function	1373731
WNT3A	89780	wingless-type MMTV integration site family, member 3A	skeletal muscle cell differentiation	Biological process	-
PRMT5	10419	protein arginine methyltransferase 5	protein-arginine omega-N symmetric methyltransferase activity	Molecular function	17709427
SYT1	6857	synaptotagmin I	glutamate secretion	Biological process	-
CXCL10	3627	chemokine (C-X-C motif) ligand 10	chemokine activity	Molecular function	12782716
ONECUT1	3175	one cut homeobox 1	regulation of transcription, DNA-templated	Biological process	10491763
PNPLA8	50640	patatin-like phospholipase domain containing 8	endoplasmic reticulum membrane	Cellular component	-
NHP2	55651	NHP2 ribonucleoprotein	nucleoplasm	Cellular component	-
RARA	5914	retinoic acid receptor, alpha	mRNA 5'-UTR binding	Molecular function	-
TCF3	6929	transcription factor 3	regulation of G1/S transition of mitotic cell cycle	Biological process	11509675
PFKL	5211	phosphofructokinase, liver	carbohydrate metabolic process	Biological process	-
DNAJC14	85406	DnaJ (Hsp40) homolog, subfamily C, member 14	extracellular exosome	Cellular component	23376485
MCM6	4175	minichromosome maintenance complex component 6	protein binding	Molecular function	11095689
HOMER1	9456	homer scaffolding protein 1	regulation of cation channel activity	Biological process	14505576
ZC3H12D	340152	zinc finger CCCH-type containing 12D	negative regulation of G1/S transition of mitotic cell cycle	Biological process	19531561
KDM7A	80853	lysine (K)-specific demethylase 7A	transcription, DNA-templated	Biological process	-
TUBB2A	7280	tubulin, beta 2A class IIa	nucleus	Cellular component	21630459
CAPN3	825	calpain 3, (p94)	positive regulation of release of sequestered calcium ion into cytosol	Biological process	-
PIF1	80119	PIF1 5'-to-3' DNA helicase	telomeric DNA binding	Molecular function	16522649
LAMP1	3916	lysosomal-associated membrane protein 1	multivesicular body	Cellular component	-
PHLDA3	23612	pleckstrin homology-like domain, family A, member 3	cytoplasm	Cellular component	-
USP13	8975	ubiquitin specific peptidase 13 (isopeptidase T-3)	regulation of proteasomal protein catabolic process	Biological process	-
TMPRSS2	7113	transmembrane protease, serine 2	scavenger receptor activity	Molecular function	-
EIF3J	8669	eukaryotic translation initiation factor 3, subunit J	cytoplasmic translation	Biological process	-
CDC42EP2	10435	CDC42 effector protein (Rho GTPase binding) 2	plasma membrane	Cellular component	10430899
UBC	7316	ubiquitin C	regulation of apoptotic process	Biological process	-
OTOS	150677	otospiralin	sensory perception of sound	Biological process	-
CLEC4M	10332	C-type lectin domain family 4, member M	viral genome replication	Biological process	11337487
C6	729	complement component 6	innate immune response	Biological process	-
TCF25	22980	transcription factor 25 (basic helix-loop-helix)	protein binding	Molecular function	16189514
ARNTL	406	aryl hydrocarbon receptor nuclear translocator-like	positive regulation of circadian rhythm	Biological process	-
MOCS3	27304	molybdenum cofactor synthesis 3	enzyme active site formation via L-cysteine persulfide	Biological process	15910006
NOC4L	79050	nucleolar complex associated 4 homolog (S. cerevisiae)	integral component of membrane	Cellular component	-
NCF1C	654817	neutrophil cytosolic factor 1C pseudogene	superoxide-generating NADPH oxidase activity	Molecular function	-
OR1A1	8383	olfactory receptor, family 1, subfamily A, member 1	integral component of membrane	Cellular component	-
SLURP1	57152	secreted LY6/PLAUR domain containing 1	negative regulation of keratinocyte proliferation	Biological process	-
THEM4	117145	thioesterase superfamily member 4	epidermal growth factor receptor signaling pathway	Biological process	-
NOSIP	51070	nitric oxide synthase interacting protein	negative regulation of nitric-oxide synthase activity	Biological process	11149895
FBXO2	26232	F-box protein 2	protein binding	Molecular function	25416956
HSP90AB4P	664618	heat shock protein 90kDa alpha (cytosolic), class B member 4, pseudogene	cytoplasm	Cellular component	-
NR2F6	2063	nuclear receptor subfamily 2, group F, member 6	gene expression	Biological process	-
CHURC1	91612	churchill domain containing 1	multicellular organismal development	Biological process	-
WWC1	23286	WW and C2 domain containing 1	establishment of cell polarity	Biological process	24682284
SLC38A9	153129	solute carrier family 38, member 9	amino acid transmembrane transport	Biological process	25567906
PAX8	7849	paired box 8	central nervous system development	Biological process	15494458
CLDN11	5010	claudin 11	integral component of membrane	Cellular component	-
DYNLL1	8655	dynein, light chain, LC8-type 1	membrane	Cellular component	19946888
ZNF268	10795	zinc finger protein 268	positive regulation of apoptotic process	Biological process	22235304
TEX101	83639	testis expressed 101	acrosomal membrane	Cellular component	-
DBI	1622	diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)	extracellular exosome	Cellular component	20458337
EPHA2	1969	EPH receptor A2	regulation of cell adhesion mediated by integrin	Biological process	10655584
STX6	10228	syntaxin 6	vesicle fusion	Biological process	10506127
TTC39A	22996	tetratricopeptide repeat domain 39A	biological_process	Biological process	-
TCF25	22980	transcription factor 25 (basic helix-loop-helix)	heart development	Biological process	16574069
TLR5	7100	toll-like receptor 5	inflammatory response	Biological process	-
FCER1A	2205	Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide	plasma membrane	Cellular component	-
NME1	4830	NME/NM23 nucleoside diphosphate kinase 1	nucleoside diphosphate phosphorylation	Biological process	-
HPGDS	27306	hematopoietic prostaglandin D synthase	small molecule metabolic process	Biological process	-
PRKCSH	5589	protein kinase C substrate 80K-H	post-translational protein modification	Biological process	-
CDK1	983	cyclin-dependent kinase 1	peptidyl-threonine phosphorylation	Biological process	11298763
ATXN3	4287	ataxin 3	cytosol	Cellular component	24548080
HSPA8	3312	heat shock 70kDa protein 8	ATPase activity, coupled	Molecular function	8530083
HSPA1A	3303	heat shock 70kDa protein 1A	regulation of cell death	Biological process	21231916
HBM	3042	hemoglobin, mu	hemoglobin complex	Cellular component	-
MUL1	79594	mitochondrial E3 ubiquitin protein ligase 1	positive regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	12761501
EGR1	1958	early growth response 1	circadian rhythm	Biological process	-
NAMPT	10135	nicotinamide phosphoribosyltransferase	cytosol	Cellular component	-
DRD1	1812	dopamine receptor D1	plasma membrane	Cellular component	-
GABRB1	2560	gamma-aminobutyric acid (GABA) A receptor, beta 1	transmembrane transport	Biological process	-
ACADL	33	acyl-CoA dehydrogenase, long chain	cellular lipid catabolic process	Biological process	-
ZNF394	84124	zinc finger protein 394	DNA binding	Molecular function	-
GLI3	2737	GLI family zinc finger 3	mediator complex	Cellular component	17000779
GOLGB1	2804	golgin B1	cis-Golgi network	Cellular component	-
NECAB1	64168	N-terminal EF-hand calcium binding protein 1	nucleoplasm	Cellular component	-
TRIM41	90933	tripartite motif containing 41	ligase activity	Molecular function	-
PIGS	94005	phosphatidylinositol glycan anchor biosynthesis, class S	C-terminal protein lipidation	Biological process	-
CARM1	10498	coactivator-associated arginine methyltransferase 1	transcription coactivator activity	Molecular function	-
FOXJ1	2302	forkhead box J1	transcription regulatory region sequence-specific DNA binding	Molecular function	9096351
EXOC3L2	90332	exocyst complex component 3-like 2	molecular_function	Molecular function	-
MYDGF	56005	myeloid-derived growth factor	apoptotic process	Biological process	-
SNAPC2	6618	small nuclear RNA activating complex, polypeptide 2, 45kDa	nucleus	Cellular component	-
TBPL2	387332	TATA box binding protein like 2	DNA binding	Molecular function	-
SUFU	51684	suppressor of fused homolog (Drosophila)	ciliary base	Cellular component	-
LAMP1	3916	lysosomal-associated membrane protein 1	autophagic cell death	Biological process	-
NR1H3	10062	nuclear receptor subfamily 1, group H, member 3	steroid hormone receptor activity	Molecular function	-
BAK1	578	BCL2-antagonist/killer 1	response to organic cyclic compound	Biological process	-
PPM1L	151742	protein phosphatase, Mg2+/Mn2+ dependent, 1L	sphingolipid metabolic process	Biological process	-
TBP	6908	TATA box binding protein	transcription elongation from RNA polymerase II promoter	Biological process	-
BAK1	578	BCL2-antagonist/killer 1	endoplasmic reticulum	Cellular component	-
CNOT6L	246175	CCR4-NOT transcription complex, subunit 6-like	gene silencing by RNA	Biological process	-
POLR2E	5434	polymerase (RNA) II (DNA directed) polypeptide E, 25kDa	transcription from RNA polymerase I promoter	Biological process	-
FAM90A22P	645558	family with sequence similarity 90, member A22 pseudogene	nucleic acid binding	Molecular function	-
SHANK1	50944	SH3 and multiple ankyrin repeat domains 1	GKAP/Homer scaffold activity	Molecular function	-
CDC42EP2	10435	CDC42 effector protein (Rho GTPase binding) 2	endomembrane system	Cellular component	-
BID	637	BH3 interacting domain death agonist	release of cytochrome c from mitochondria	Biological process	17052454
WDR27	253769	WD repeat domain 27	protein binding	Molecular function	25416956
NRP2	8828	neuropilin 2	sympathetic neuron projection extension	Biological process	-
KCNJ3	3760	potassium channel, inwardly rectifying subfamily J, member 3	inward rectifier potassium channel activity	Molecular function	12297500
P2RX2	22953	purinergic receptor P2X, ligand gated ion channel, 2	detection of hypoxic conditions in blood by carotid body chemoreceptor signaling	Biological process	-
SLC6A11	6538	solute carrier family 6 (neurotransmitter transporter), member 11	plasma membrane	Cellular component	-
FLCN	201163	folliculin	hemopoiesis	Biological process	-
GBP4	115361	guanylate binding protein 4	metabolic process	Biological process	-
RHBDL3	162494	rhomboid, veinlet-like 3 (Drosophila)	calcium ion binding	Molecular function	-
NR4A2	4929	nuclear receptor subfamily 4, group A, member 2	general adaptation syndrome	Biological process	-
PI4KB	5298	phosphatidylinositol 4-kinase, catalytic, beta	phospholipid metabolic process	Biological process	-
PLA2G10	8399	phospholipase A2, group X	positive regulation of cellular protein metabolic process	Biological process	18511424
FGF10	2255	fibroblast growth factor 10	positive regulation of DNA repair	Biological process	14975937
NEK5	341676	NIMA-related kinase 5	positive regulation of cysteine-type endopeptidase activity	Biological process	-
RECQL	5965	RecQ helicase-like	DNA duplex unwinding	Biological process	7527136
CYBA	1535	cytochrome b-245, alpha polypeptide	electron carrier activity	Molecular function	2243141
CYP1A1	1543	cytochrome P450, family 1, subfamily A, polypeptide 1	demethylation	Biological process	-
PSEN2	5664	presenilin 2	positive regulation of coagulation	Biological process	-
GSTO1	9446	glutathione S-transferase omega 1	cytosol	Cellular component	-
MARCKS	4082	myristoylated alanine-rich protein kinase C substrate	centrosome	Cellular component	-
FBXW8	26259	F-box and WD repeat domain containing 8	protein binding	Molecular function	17314511
NOSIP	51070	nitric oxide synthase interacting protein	small molecule metabolic process	Biological process	-
OR4Q2	390432	olfactory receptor, family 4, subfamily Q, member 2 (gene/pseudogene)	G-protein coupled receptor signaling pathway	Biological process	-
GPAM	57678	glycerol-3-phosphate acyltransferase, mitochondrial	acyl-CoA metabolic process	Biological process	-
BICD1	636	bicaudal D homolog 1 (Drosophila)	regulation of proteinase activated receptor activity	Biological process	-
GPRC5B	51704	G protein-coupled receptor, class C, group 5, member B	cytoplasmic vesicle membrane	Cellular component	-
AASS	10157	aminoadipate-semialdehyde synthase	oxidation-reduction process	Biological process	-
EGFL7	51162	EGF-like-domain, multiple 7	blood vessel development	Biological process	-
NOTO	344022	notochord homeobox	transcription, DNA-templated	Biological process	-
AGPAT1	10554	1-acylglycerol-3-phosphate O-acyltransferase 1	glycerophospholipid biosynthetic process	Biological process	-
DHRS12	79758	dehydrogenase/reductase (SDR family) member 12	oxidation-reduction process	Biological process	-
IFNA5	3442	interferon, alpha 5	regulation of type I interferon-mediated signaling pathway	Biological process	-
TGFBR3	7049	transforming growth factor, beta receptor III	coreceptor activity	Molecular function	10746731
HIST1H3C	8352	histone cluster 1, H3c	nucleus	Cellular component	21630459
HSD17B6	8630	hydroxysteroid (17-beta) dehydrogenase 6	catalytic activity	Molecular function	9188497
MYH9	4627	myosin, heavy chain 9, non-muscle	blood vessel endothelial cell migration	Biological process	16403913
UPK1B	7348	uroplakin 1B	apical plasma membrane	Cellular component	-
SNAPIN	23557	SNAP-associated protein	autophagosome maturation	Biological process	-
CD34	947	CD34 molecule	positive regulation of granulocyte colony-stimulating factor production	Biological process	17261663
CORO1A	11151	coronin, actin binding protein, 1A	innate immune response	Biological process	17341475
NKX2-4	644524	NK2 homeobox 4	regulation of transcription, DNA-templated	Biological process	-
CHTOP	26097	chromatin target of PRMT1	nucleolus	Cellular component	-
CEP120	153241	centrosomal protein 120kDa	centrosome	Cellular component	21399614
PRMT2	3275	protein arginine methyltransferase 2	nucleolus	Cellular component	-
WRB	7485	tryptophan rich basic protein	integral component of membrane	Cellular component	-
BDP1	55814	B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB	transcription from RNA polymerase III promoter	Biological process	-
E2F6	1876	E2F transcription factor 6	transcription, DNA-templated	Biological process	-
JUN	3725	jun proto-oncogene	double-stranded DNA binding	Molecular function	-
ADORA1	134	adenosine A1 receptor	inflammatory response	Biological process	8360491
CAPZB	832	capping protein (actin filament) muscle Z-line, beta	negative regulation of filopodium assembly	Biological process	-
ACVR2A	92	activin A receptor, type IIA	activin receptor signaling pathway	Biological process	12665502
TTK	7272	TTK protein kinase	ATP binding	Molecular function	-
GAP43	2596	growth associated protein 43	regulation of filopodium assembly	Biological process	14978216
EIF3K	27335	eukaryotic translation initiation factor 3, subunit K	eukaryotic 48S preinitiation complex	Cellular component	-
HMGB1	3146	high mobility group box 1	protein binding	Molecular function	11748232
ZDHHC16	84287	zinc finger, DHHC-type containing 16	endoplasmic reticulum membrane	Cellular component	-
NFE2	4778	nuclear factor, erythroid 2	cell-cell signaling	Biological process	-
GCM2	9247	glial cells missing homolog 2 (Drosophila)	metal ion binding	Molecular function	-
SPON1	10418	spondin 1, extracellular matrix protein	protein binding	Molecular function	14983046
ROBO2	6092	roundabout, axon guidance receptor, homolog 2 (Drosophila)	cellular response to hormone stimulus	Biological process	18566128
HRAS	3265	Harvey rat sarcoma viral oncogene homolog	fibroblast growth factor receptor signaling pathway	Biological process	-
PPIP5K1	9677	diphosphoinositol pentakisphosphate kinase 1	inositol phosphate metabolic process	Biological process	-
MYBL2	4605	v-myb avian myeloblastosis viral oncogene homolog-like 2	G2/M transition of mitotic cell cycle	Biological process	-
HDAC5	10014	histone deacetylase 5	histone H3-K9 deacetylation	Biological process	-
EPHA1	2041	EPH receptor A1	ATP binding	Molecular function	-
GNG5	2787	guanine nucleotide binding protein (G protein), gamma 5	extracellular exosome	Cellular component	19056867
EIF4A3	9775	eukaryotic translation initiation factor 4A3	cytosol	Cellular component	-
MYOCD	93649	myocardin	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	22157009
LRBA	987	LPS-responsive vesicle trafficking, beach and anchor containing	endosomal transport	Biological process	-
CDKN2B	1030	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	mitotic cell cycle	Biological process	-
UBE2A	7319	ubiquitin-conjugating enzyme E2A	histone H2A ubiquitination	Biological process	11953320
S1PR4	8698	sphingosine-1-phosphate receptor 4	sphingosine-1-phosphate signaling pathway	Biological process	-
PTOV1	53635	prostate tumor overexpressed 1	perinuclear region of cytoplasm	Cellular component	-
SYTL1	84958	synaptotagmin-like 1	exocytosis	Biological process	18266782
NIF3L1	60491	NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)	mitochondrion	Cellular component	-
ZNF362	149076	zinc finger protein 362	DNA binding	Molecular function	-
TUBA1A	7846	tubulin, alpha 1a	protein polymerization	Biological process	-
F2RL1	2150	coagulation factor II (thrombin) receptor-like 1	pseudopodium	Cellular component	-
RRM1	6240	ribonucleotide reductase M1	protein binding	Molecular function	22632967
CDKN1B	1027	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	inner ear development	Biological process	-
WNK4	65266	WNK lysine deficient protein kinase 4	protein localization	Biological process	-
RAB13	5872	RAB13, member RAS oncogene family	bicellular tight junction assembly	Biological process	12058051
DAB2IP	153090	DAB2 interacting protein	phosphatidylinositol 3-kinase binding	Molecular function	19033661
FOLR2	2350	folate receptor 2 (fetal)	extracellular region	Cellular component	-
NR1H2	7376	nuclear receptor subfamily 1, group H, member 2	positive regulation of cellular protein metabolic process	Biological process	17186944
DRD2	1813	dopamine receptor D2	peristalsis	Biological process	-
RPL8	6132	ribosomal protein L8	viral process	Biological process	-
LRG1	116844	leucine-rich alpha-2-glycoprotein 1	molecular_function	Molecular function	-
PRDM2	7799	PR domain containing 2, with ZNF domain	histone-lysine N-methyltransferase activity	Molecular function	-
MYH6	4624	myosin, heavy chain 6, cardiac muscle, alpha	cardiac muscle fiber development	Biological process	-
ATP7A	538	ATPase, Cu++ transporting, alpha polypeptide	hair follicle morphogenesis	Biological process	-
PRMT2	3275	protein arginine methyltransferase 2	positive regulation of transcription, DNA-templated	Biological process	12039952
P2RX5	5026	purinergic receptor P2X, ligand gated ion channel, 5	positive regulation of calcium-mediated signaling	Biological process	17895406
USP14	9097	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)	ubiquitin-specific protease activity	Molecular function	23958854
C18orf15	147276	chromosome 18 open reading frame 15	integral component of membrane	Cellular component	-
SPPL3	121665	signal peptide peptidase like 3	integral component of cytoplasmic side of endoplasmic reticulum membrane	Cellular component	15385547
DICER1	23405	dicer 1, ribonuclease type III	spindle assembly	Biological process	-
ALX3	257	ALX homeobox 3	pattern specification process	Biological process	-
HOXD9	3235	homeobox D9	anterior/posterior pattern specification	Biological process	-
TOPBP1	11073	topoisomerase (DNA) II binding protein 1	cellular response to DNA damage stimulus	Biological process	12773567
LIN7A	8825	lin-7 homolog A (C. elegans)	bicellular tight junction	Cellular component	-
REST	5978	RE1-silencing transcription factor	negative regulation of transcription, DNA-templated	Biological process	7871435
SNRPB	6628	small nuclear ribonucleoprotein polypeptides B and B1	cytosol	Cellular component	-
ULK3	25989	unc-51 like kinase 3	autophagosome assembly	Biological process	-
CALM1	801	calmodulin 1 (phosphorylase kinase, delta)	muscle contraction	Biological process	-
PPFIA1	8500	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1	cytosol	Cellular component	-
VDAC3	7419	voltage-dependent anion channel 3	pore complex	Cellular component	-
DICER1	23405	dicer 1, ribonuclease type III	branching morphogenesis of an epithelial tube	Biological process	-
NHLH2	4808	nescient helix loop helix 2	RNA polymerase II activating transcription factor binding	Molecular function	16314316
OR5H14	403273	olfactory receptor, family 5, subfamily H, member 14	G-protein coupled receptor signaling pathway	Biological process	-
CDYL	9425	chromodomain protein, Y-like	protein binding	Molecular function	16415788
KIRREL2	84063	kin of IRRE like 2 (Drosophila)	negative regulation of protein phosphorylation	Biological process	-
SPOP	8405	speckle-type POZ protein	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	Biological process	-
AMIGO2	347902	adhesion molecule with Ig-like domain 2	nucleus	Cellular component	-
ARCN1	372	archain 1	clathrin adaptor complex	Cellular component	-
SPINK8	646424	serine peptidase inhibitor, Kazal type 8 (putative)	extracellular region	Cellular component	-
ARNT	405	aryl hydrocarbon receptor nuclear translocator	transcription coactivator activity	Molecular function	-
MSTN	2660	myostatin	heparin binding	Molecular function	-
PMAIP1	5366	phorbol-12-myristate-13-acetate-induced protein 1	positive regulation of apoptotic process	Biological process	17289999
IFT27	11020	intraflagellar transport 27	cilium	Cellular component	25443296
S1PR1	1901	sphingosine-1-phosphate receptor 1	cytosol	Cellular component	-
PRPSAP1	5635	phosphoribosyl pyrophosphate synthetase-associated protein 1	negative regulation of kinase activity	Biological process	-
AS3MT	57412	arsenite methyltransferase	methylarsonite methyltransferase activity	Molecular function	-
OR10H3	26532	olfactory receptor, family 10, subfamily H, member 3	olfactory receptor activity	Molecular function	-
PRKCD	5580	protein kinase C, delta	negative regulation of MAP kinase activity	Biological process	19279008
GPC2	221914	glypican 2	endoplasmic reticulum	Cellular component	-
WASL	8976	Wiskott-Aldrich syndrome-like	innate immune response	Biological process	-
UMOD	7369	uromodulin	metanephric ascending thin limb development	Biological process	-
CA7	766	carbonic anhydrase VII	carbonate dehydratase activity	Molecular function	-
CDK4	1019	cyclin-dependent kinase 4	circadian rhythm	Biological process	-
NRP1	8829	neuropilin 1	renal artery morphogenesis	Biological process	-
PIK3CB	5291	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta	cell migration	Biological process	21035500
RNF130	55819	ring finger protein 130	protein ubiquitination	Biological process	-
GPR65	8477	G protein-coupled receptor 65	positive regulation of cAMP biosynthetic process	Biological process	15618224
OR52E5	390082	olfactory receptor, family 52, subfamily E, member 5	G-protein coupled receptor activity	Molecular function	-
SGK1	6446	serum/glucocorticoid regulated kinase 1	regulation of cell migration	Biological process	20919962
PFKP	5214	phosphofructokinase, platelet	ATP binding	Molecular function	-
COL10A1	1300	collagen, type X, alpha 1	endochondral ossification	Biological process	-
ARHGEF11	9826	Rho guanine nucleotide exchange factor (GEF) 11	protein binding	Molecular function	10026210
OLFM2	93145	olfactomedin 2	alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex	Cellular component	-
EHD2	30846	EH-domain containing 2	protein domain specific binding	Molecular function	-
GEM	2669	GTP binding protein overexpressed in skeletal muscle	immune response	Biological process	7912851
TNFSF15	9966	tumor necrosis factor (ligand) superfamily, member 15	integral component of membrane	Cellular component	9872942
IL4	3565	interleukin 4	positive regulation of T cell differentiation	Biological process	20554961
H3F3B	3021	H3 histone, family 3B (H3.3B)	small GTPase mediated signal transduction	Biological process	-
PAK7	57144	p21 protein (Cdc42/Rac)-activated kinase 7	Rac GTPase binding	Molecular function	-
ZNF587	84914	zinc finger protein 587	protein binding	Molecular function	25416956
ARF6	382	ADP-ribosylation factor 6	regulation of filopodium assembly	Biological process	14978216
MEN1	4221	multiple endocrine neoplasia I	chromatin	Cellular component	12874027
FOXO1	2308	forkhead box O1	cellular glucose homeostasis	Biological process	22510882
HSD17B1	3292	hydroxysteroid (17-beta) dehydrogenase 1	catalytic activity	Molecular function	8547176
FGF8	2253	fibroblast growth factor 8 (androgen-induced)	patterning of blood vessels	Biological process	-
ST8SIA6	338596	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6	post-translational protein modification	Biological process	-
HOXA5	3202	homeobox A5	DNA binding	Molecular function	8657138
TMEM120B	144404	transmembrane protein 120B	biological_process	Biological process	-
SHC1	6464	SHC (Src homology 2 domain containing) transforming protein 1	single organismal cell-cell adhesion	Biological process	-
GPR143	4935	G protein-coupled receptor 143	neuropeptide signaling pathway	Biological process	18828673
NCAM1	4684	neural cell adhesion molecule 1	cell surface	Cellular component	10766765
RNF14	9604	ring finger protein 14	nucleus	Cellular component	11322894
PTGIS	5740	prostaglandin I2 (prostacyclin) synthase	positive regulation of peroxisome proliferator activated receptor signaling pathway	Biological process	11551955
CAPZB	832	capping protein (actin filament) muscle Z-line, beta	actin filament	Cellular component	-
RAB2B	84932	RAB2B, member RAS oncogene family	GTP binding	Molecular function	-
LYRM2	57226	LYR motif containing 2	protein binding	Molecular function	25416956
SLC9A1	6548	solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1	cardiac muscle cell differentiation	Biological process	-
CENPC	1060	centromere protein C	mitotic nuclear division	Biological process	-
OR11G2	390439	olfactory receptor, family 11, subfamily G, member 2	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
PDE4D	5144	phosphodiesterase 4D, cAMP-specific	regulation of heart rate	Biological process	16213210
ATG16L2	89849	autophagy related 16-like 2 (S. cerevisiae)	nucleoplasm	Cellular component	-
RELN	5649	reelin	positive regulation of dendritic spine morphogenesis	Biological process	-
GAL3ST4	79690	galactose-3-O-sulfotransferase 4	galactose 3-O-sulfotransferase activity	Molecular function	11333265
MAP3K1	4214	mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase	cytoplasm	Cellular component	-
NCOR1	9611	nuclear receptor corepressor 1	membrane	Cellular component	19946888
ANXA2	302	annexin A2	extrinsic component of plasma membrane	Cellular component	-
GABPB2	126626	GA binding protein transcription factor, beta subunit 2	protein heterodimerization activity	Molecular function	9857059
DNAI1	27019	dynein, axonemal, intermediate chain 1	outer dynein arm	Cellular component	11231901
BAD	572	BCL2-associated agonist of cell death	positive regulation of release of cytochrome c from mitochondria	Biological process	17289999
MGRN1	23295	mahogunin ring finger 1, E3 ubiquitin protein ligase	protein monoubiquitination	Biological process	17229889
DLG4	1742	discs, large homolog 4 (Drosophila)	axon guidance	Biological process	-
SRCAP	10847	Snf2-related CREBBP activator protein	protein complex	Cellular component	14966270
HIST1H2BK	85236	histone cluster 1, H2bk	antibacterial humoral response	Biological process	12860195
MICAL1	64780	microtubule associated monooxygenase, calponin and LIM domain containing 1	Rab GTPase binding	Molecular function	-
BMP6	654	bone morphogenetic protein 6	endochondral ossification	Biological process	-
ZAK	51776	sterile alpha motif and leucine zipper containing kinase AZK	cell cycle checkpoint	Biological process	15342622
GABPA	2551	GA binding protein transcription factor, alpha subunit 60kDa	in utero embryonic development	Biological process	-
BAK1	578	BCL2-antagonist/killer 1	mitochondrial outer membrane	Cellular component	-
HNF1B	6928	HNF1 homeobox B	hepatoblast differentiation	Biological process	-
EBF2	64641	early B-cell factor 2	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
PREX1	57580	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	intracellular membrane-bounded organelle	Cellular component	-
APOA5	116519	apolipoprotein A-V	phospholipid binding	Molecular function	12810715
AK6	102157402	adenylate kinase 6	protein binding	Molecular function	16079131
PTRF	284119	polymerase I and transcript release factor	transcription initiation from RNA polymerase I promoter	Biological process	9582279
YAP1	10413	Yes-associated protein 1	negative regulation of nucleic acid-templated transcription	Biological process	18158288
DLG1	1739	discs, large homolog 1 (Drosophila)	cytosol	Cellular component	-
PRKAR1B	5575	protein kinase, cAMP-dependent, regulatory, type I, beta	plasma membrane	Cellular component	-
PAPOLG	64895	poly(A) polymerase gamma	ATP binding	Molecular function	-
HNRNPDL	9987	heterogeneous nuclear ribonucleoprotein D-like	cytoplasm	Cellular component	-
ELOVL7	79993	ELOVL fatty acid elongase 7	long-chain fatty-acyl-CoA biosynthetic process	Biological process	-
TP53	7157	tumor protein p53	core promoter sequence-specific DNA binding	Molecular function	-
PTRF	284119	polymerase I and transcript release factor	poly(A) RNA binding	Molecular function	22658674
STEAP4	79689	STEAP family member 4	ferric iron import into cell	Biological process	-
NRL	4901	neural retina leucine zipper	transcription from RNA polymerase II promoter	Biological process	8939891
MYLK3	91807	myosin light chain kinase 3	ATP binding	Molecular function	-
CD8A	925	CD8a molecule	immune response	Biological process	11131152
ZBTB16	7704	zinc finger and BTB domain containing 16	protein homodimerization activity	Molecular function	8622986
TSPAN4	7106	tetraspanin 4	plasma membrane	Cellular component	9360996
ZFPM1	161882	zinc finger protein, FOG family member 1	RNA polymerase II transcription factor binding	Molecular function	11675338
ZNF285	26974	zinc finger protein 285	metal ion binding	Molecular function	-
STX16	8675	syntaxin 16	Golgi apparatus	Cellular component	9464276
SIRT1	23411	sirtuin 1	cell aging	Biological process	11672523
TMC1	117531	transmembrane channel-like 1	external side of plasma membrane	Cellular component	-
LCN15	389812	lipocalin 15	lipid metabolic process	Biological process	-
WWTR1	25937	WW domain containing transcription regulator 1	transcription coactivator activity	Molecular function	11118213
HRK	8739	harakiri, BCL2 interacting protein	apoptotic process	Biological process	-
TBC1D17	79735	TBC1 domain family, member 17	autophagosome	Cellular component	-
INHBC	3626	inhibin, beta C	growth	Biological process	-
PARVB	29780	parvin, beta	lamellipodium assembly	Biological process	18325335
CDKAL1	54901	CDK5 regulatory subunit associated protein 1-like 1	metal ion binding	Molecular function	-
KRAS	3845	Kirsten rat sarcoma viral oncogene homolog	cytokine-mediated signaling pathway	Biological process	-
BMPR1B	658	bone morphogenetic protein receptor, type IB	BMP signaling pathway	Biological process	-
RER1	11079	retention in endoplasmic reticulum sorting receptor 1	acetylcholine receptor binding	Molecular function	-
PLXNB1	5364	plexin B1	integral component of plasma membrane	Cellular component	10520995
HBG2	3048	hemoglobin, gamma G	oxygen binding	Molecular function	-
MT1H	4496	metallothionein 1H	protein binding	Molecular function	12646258
GRHL1	29841	grainyhead-like 1 (Drosophila)	positive regulation of transcription from RNA polymerase II promoter	Biological process	12175488
SOX13	9580	SRY (sex determining region Y)-box 13	sequence-specific DNA binding	Molecular function	-
UBB	7314	ubiquitin B	viral process	Biological process	-
WTIP	126374	Wilms tumor 1 interacting protein	zinc ion binding	Molecular function	-
CTNS	1497	cystinosin, lysosomal cystine transporter	ion transport	Biological process	-
SIRT1	23411	sirtuin 1	negative regulation of sequence-specific DNA binding transcription factor activity	Biological process	17505061
ATP7A	538	ATPase, Cu++ transporting, alpha polypeptide	neuronal cell body	Cellular component	-
LAMP1	3916	lysosomal-associated membrane protein 1	endosome membrane	Cellular component	-
HEXB	3074	hexosaminidase B (beta polypeptide)	carbohydrate metabolic process	Biological process	-
ACP5	54	acid phosphatase 5, tartrate resistant	acid phosphatase activity	Molecular function	-
DPP7	29952	dipeptidyl-peptidase 7	cytoplasmic membrane-bounded vesicle	Cellular component	-
MRI1	84245	methylthioribose-1-phosphate isomerase 1	sulfur amino acid metabolic process	Biological process	-
EPAS1	2034	endothelial PAS domain protein 1	regulation of heart rate	Biological process	-
SPNS1	83985	spinster homolog 1 (Drosophila)	mitochondrial inner membrane	Cellular component	-
CSE1L	1434	CSE1 chromosome segregation 1-like (yeast)	protein binding	Molecular function	17719542
FAT4	79633	FAT atypical cadherin 4	hippo signaling	Biological process	-
P2RX2	22953	purinergic receptor P2X, ligand gated ion channel, 2	integral component of plasma membrane	Cellular component	23345450
NFIB	4781	nuclear factor I/B	Type II pneumocyte differentiation	Biological process	-
SOX30	11063	SRY (sex determining region Y)-box 30	protein binding	Molecular function	21516116
EPHA5	2044	EPH receptor A5	GPI-linked ephrin receptor activity	Molecular function	-
IL2RG	3561	interleukin 2 receptor, gamma	immune response	Biological process	8266078
SOCS1	8651	suppressor of cytokine signaling 1	regulation of protein phosphorylation	Biological process	-
RHOA	387	ras homolog family member A	wound healing, spreading of cells	Biological process	-
ARHGAP4	393	Rho GTPase activating protein 4	cytoplasm	Cellular component	-
UBB	7314	ubiquitin B	cytosol	Cellular component	-
RPLP1	6176	ribosomal protein, large, P1	SRP-dependent cotranslational protein targeting to membrane	Biological process	-
ERCC1	2067	excision repair cross-complementation group 1	protein binding	Molecular function	11058119
KIAA2018	205717	KIAA2018	DNA binding	Molecular function	-
TRIM71	131405	tripartite motif containing 71, E3 ubiquitin protein ligase	G1/S transition of mitotic cell cycle	Biological process	-
FOXP1	27086	forkhead box P1	protein binding	Molecular function	18347093
TRIP11	9321	thyroid hormone receptor interactor 11	Golgi membrane	Cellular component	-
FGD5	152273	FYVE, RhoGEF and PH domain containing 5	ruffle	Cellular component	-
CDKN1B	1027	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	response to amino acid	Biological process	-
HNRNPR	10236	heterogeneous nuclear ribonucleoprotein R	nucleolus	Cellular component	9421497
RPL35A	6165	ribosomal protein L35a	rRNA processing	Biological process	18697920
NPR3	4883	natriuretic peptide receptor 3	pancreatic juice secretion	Biological process	-
B3GALT1	8708	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity	Molecular function	9582303
TGFB1	7040	transforming growth factor, beta 1	ureteric bud development	Biological process	-
GLI3	2737	GLI family zinc finger 3	artery development	Biological process	-
NOS2	4843	nitric oxide synthase 2, inducible	cytoplasm	Cellular component	12085352
MSTN	2660	myostatin	regulation of MAPK cascade	Biological process	-
VWC2	375567	von Willebrand factor C domain containing 2	interstitial matrix	Cellular component	-
HLA-DRB3	3125	major histocompatibility complex, class II, DR beta 3	regulation of interleukin-10 secretion	Biological process	20543955
DEPTOR	64798	DEP domain containing MTOR-interacting protein	intracellular	Cellular component	-
NT5E	4907	5'-nucleotidase, ecto (CD73)	anchored component of membrane	Cellular component	-
RAB14	51552	RAB14, member RAS oncogene family	embryo development	Biological process	-
IDE	3416	insulin-degrading enzyme	ubiquitin binding	Molecular function	21185309
HJURP	55355	Holliday junction recognition protein	nucleolus	Cellular component	-
KDR	3791	kinase insert domain receptor	transmembrane receptor protein tyrosine kinase activity	Molecular function	1417831
TBC1D5	9779	TBC1 domain family, member 5	protein transport	Biological process	-
HIST1H1E	3008	histone cluster 1, H1e	nucleosome	Cellular component	-
PTHLH	5744	parathyroid hormone-like hormone	female pregnancy	Biological process	10828849
MTOR	2475	mechanistic target of rapamycin (serine/threonine kinase)	Golgi membrane	Cellular component	-
CAV1	857	caveolin 1, caveolae protein, 22kDa	vasoconstriction	Biological process	-
AP1G1	164	adaptor-related protein complex 1, gamma 1 subunit	regulation of defense response to virus by virus	Biological process	-
SPG20	23111	spastic paraplegia 20 (Troyer syndrome)	cytoplasm	Cellular component	-
TNNT2	7139	troponin T type 2 (cardiac)	regulation of muscle contraction	Biological process	-
ITGA9	3680	integrin, alpha 9	integrin alpha9-beta1 complex	Cellular component	-
SLK	9748	STE20-like kinase	stress-activated protein kinase signaling cascade	Biological process	-
SLC5A6	8884	solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6	biotin metabolic process	Biological process	-
SCN1B	6324	sodium channel, voltage gated, type I beta subunit	cardiac conduction	Biological process	-
OR52Z1	283110	olfactory receptor, family 52, subfamily Z, member 1 (gene/pseudogene)	G-protein coupled receptor activity	Molecular function	-
UBXN2A	165324	UBX domain protein 2A	ubiquitin binding	Molecular function	-
DNM1L	10059	dynamin 1-like	protein localization to mitochondrion	Biological process	-
ZNF541	84215	zinc finger protein 541	cell differentiation	Biological process	-
CDK9	1025	cyclin-dependent kinase 9	protein kinase activity	Molecular function	8170997
CENPU	79682	centromere protein U	regulation of transcription, DNA-templated	Biological process	-
ZNF107	51427	zinc finger protein 107	metal ion binding	Molecular function	-
HAND1	9421	heart and neural crest derivatives expressed 1	nucleolus	Cellular component	-
TFRC	7037	transferrin receptor	external side of plasma membrane	Cellular component	-
NR1H4	9971	nuclear receptor subfamily 1, group H, member 4	RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription	Molecular function	21757002
PLEKHG5	57449	pleckstrin homology domain containing, family G (with RhoGef domain) member 5	apoptotic signaling pathway	Biological process	-
BMP2	650	bone morphogenetic protein 2	positive regulation of gene expression	Biological process	16243309
MST1R	4486	macrophage stimulating 1 receptor	positive regulation of MAP kinase activity	Biological process	12676986
EEF1A2	1917	eukaryotic translation elongation factor 1 alpha 2	nucleus	Cellular component	12426392
LRRK2	120892	leucine-rich repeat kinase 2	negative regulation of late endosome to lysosome transport	Biological process	23949442
RAC3	5881	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	positive regulation of cell adhesion mediated by integrin	Biological process	11756406
RPSA	3921	ribosomal protein SA	protein binding	Molecular function	16263087
UBE2D4	51619	ubiquitin-conjugating enzyme E2D 4 (putative)	ATP binding	Molecular function	-
F2R	2149	coagulation factor II (thrombin) receptor	activation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	10692450
FXN	2395	frataxin	iron incorporation into metallo-sulfur cluster	Biological process	12785837
ASH2L	9070	ash2 (absent, small, or homeotic)-like (Drosophila)	transcription, DNA-templated	Biological process	10393421
EPHB2	2048	EPH receptor B2	extracellular region	Cellular component	-
ZNF575	284346	zinc finger protein 575	metal ion binding	Molecular function	-
EPO	2056	erythropoietin	response to interleukin-1	Biological process	-
USP30	84749	ubiquitin specific peptidase 30	protein K11-linked deubiquitination	Biological process	25621951
HS6ST1	9394	heparan sulfate 6-O-sulfotransferase 1	sulfotransferase activity	Molecular function	9535912
IPO4	79711	importin 4	protein binding	Molecular function	17616579
SRCIN1	80725	SRC kinase signaling inhibitor 1	cytoplasm	Cellular component	19146815
TPD52	7163	tumor protein D52	protein homodimerization activity	Molecular function	9484778
KCNH3	23416	potassium channel, voltage gated eag related subfamily H, member 3	synaptic transmission	Biological process	-
HSPA9	3313	heat shock 70kDa protein 9 (mortalin)	cellular protein metabolic process	Biological process	-
SNAP91	9892	synaptosomal-associated protein, 91kDa	clathrin coat assembly	Biological process	-
PCDHA1	56147	protocadherin alpha 1	calcium ion binding	Molecular function	-
BCKDHA	593	branched chain keto acid dehydrogenase E1, alpha polypeptide	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity	Molecular function	-
TMEM97	27346	transmembrane protein 97	nuclear membrane	Cellular component	19583955
ASB6	140459	ankyrin repeat and SOCS box containing 6	intracellular signal transduction	Biological process	-
UTRN	7402	utrophin	zinc ion binding	Molecular function	-
JAK3	3718	Janus kinase 3	cytosol	Cellular component	-
PLOD1	5351	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1	oxidation-reduction process	Biological process	1577494
AKAP4	8852	A kinase (PRKA) anchor protein 4	sperm motility	Biological process	9822690
PREB	10113	prolactin regulatory element binding	cellular protein metabolic process	Biological process	-
PRMT7	54496	protein arginine methyltransferase 7	regulation of transcription, DNA-templated	Biological process	-
GPER1	2852	G protein-coupled estrogen receptor 1	dendritic spine head	Cellular component	-
NRTN	4902	neurturin	nervous system development	Biological process	9286710
EIF2AK3	9451	eukaryotic translation initiation factor 2-alpha kinase 3	lactation	Biological process	-
SCN4B	6330	sodium channel, voltage gated, type IV beta subunit	positive regulation of sodium ion transport	Biological process	17592081
ARL9	132946	ADP-ribosylation factor-like 9	GTP binding	Molecular function	-
ANK2	287	ankyrin 2, neuronal	neuron projection	Cellular component	-
MCRS1	10445	microspherule protein 1	histone H4-K16 acetylation	Biological process	20018852
CEACAM6	4680	carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)	anchored component of membrane	Cellular component	-
DUOX2	50506	dual oxidase 2	extracellular exosome	Cellular component	19199708
WBSCR22	114049	Williams Beuren syndrome chromosome region 22	methylation	Biological process	-
MFAP1	4236	microfibrillar-associated protein 1	microfibril	Cellular component	1374398
FKBP8	23770	FK506 binding protein 8, 38kDa	intracellular signal transduction	Biological process	10197430
ASCC3	10973	activating signal cointegrator 1 complex subunit 3	ATP-dependent 3'-5' DNA helicase activity	Molecular function	22055184
AEN	64782	apoptosis enhancing nuclease	nucleic acid phosphodiester bond hydrolysis	Biological process	-
SSFA2	6744	sperm specific antigen 2	nucleoplasm	Cellular component	-
TNMD	64102	tenomodulin	negative regulation of endothelial cell proliferation	Biological process	-
ZNF554	115196	zinc finger protein 554	transcription, DNA-templated	Biological process	-
ARL1	400	ADP-ribosylation factor-like 1	cytoplasm	Cellular component	-
LYZL1	84569	lysozyme-like 1	lysozyme activity	Molecular function	-
SMARCA5	8467	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	ATP binding	Molecular function	12972596
PSEN2	5664	presenilin 2	negative regulation of protein complex assembly	Biological process	-
COMMD9	29099	COMM domain containing 9	sodium ion transport	Biological process	-
RAB5B	5869	RAB5B, member RAS oncogene family	early endosome	Cellular component	-
C16orf45	89927	chromosome 16 open reading frame 45	negative regulation of microtubule depolymerization	Biological process	-
STAU1	6780	staufen double-stranded RNA binding protein 1	protein phosphatase 1 binding	Molecular function	-
EML1	2009	echinoderm microtubule associated protein like 1	microtubule cytoskeleton organization	Biological process	-
SLC30A1	7779	solute carrier family 30 (zinc transporter), member 1	cadmium ion transmembrane transport	Biological process	-
RAB17	64284	RAB17, member RAS oncogene family	dendrite	Cellular component	-
PLEKHG2	64857	pleckstrin homology domain containing, family G (with RhoGef domain) member 2	neurotrophin TRK receptor signaling pathway	Biological process	-
MEDAG	84935	mesenteric estrogen-dependent adipogenesis	positive regulation of fat cell differentiation	Biological process	-
RPH3AL	9501	rabphilin 3A-like (without C2 domains)	cytoplasm	Cellular component	9367993
AP1S2	8905	adaptor-related protein complex 1, sigma 2 subunit	membrane organization	Biological process	-
CTGF	1490	connective tissue growth factor	plasma membrane	Cellular component	10809757
RAPGEFL1	51195	Rap guanine nucleotide exchange factor (GEF)-like 1	small GTPase mediated signal transduction	Biological process	-
BDKRB2	624	bradykinin receptor B2	cytosol	Cellular component	10653985
PVRL1	5818	poliovirus receptor-related 1 (herpesvirus entry mediator C)	viral entry into host cell	Biological process	12885915
UNCX	340260	UNC homeobox	regulation of cell differentiation	Biological process	-
FPR2	2358	formyl peptide receptor 2	plasma membrane	Cellular component	-
RPL37A	6168	ribosomal protein L37a	viral process	Biological process	-
TFRC	7037	transferrin receptor	transferrin transport	Biological process	-
GCKR	2646	glucokinase (hexokinase 4) regulator	cellular glucose homeostasis	Biological process	-
RNFT2	84900	ring finger protein, transmembrane 2	integral component of membrane	Cellular component	-
IDS	3423	iduronate 2-sulfatase	metal ion binding	Molecular function	-
ADRA1B	147	adrenoceptor alpha 1B	nucleus	Cellular component	22120526
GNA12	2768	guanine nucleotide binding protein (G protein) alpha 12	signal transducer activity	Molecular function	-
CHMP5	51510	charged multivesicular body protein 5	multivesicular body sorting pathway	Biological process	15644320
PSMB8	5696	proteasome (prosome, macropain) subunit, beta type, 8	regulation of cellular amino acid metabolic process	Biological process	-
RING1	6015	ring finger protein 1	negative regulation of transcription, DNA-templated	Biological process	9199346
PDPK1	5170	3-phosphoinositide dependent protein kinase 1	activation of protein kinase B activity	Biological process	9368760
NIPBL	25836	Nipped-B homolog (Drosophila)	cellular protein localization	Biological process	17468178
PNPT1	87178	polyribonucleotide nucleotidyltransferase 1	3'-5'-exoribonuclease activity	Molecular function	19509288
NFAT5	10725	nuclear factor of activated T-cells 5, tonicity-responsive	transcription from RNA polymerase II promoter	Biological process	10051678
ARHGAP44	9912	Rho GTPase activating protein 44	regulation of small GTPase mediated signal transduction	Biological process	-
NYX	60506	nyctalopin	response to stimulus	Biological process	-
CRYAB	1410	crystallin, alpha B	extracellular exosome	Cellular component	19056867
BABAM1	29086	BRISC and BRCA1 A complex member 1	protein K63-linked deubiquitination	Biological process	19261746
BAD	572	BCL2-associated agonist of cell death	type B pancreatic cell proliferation	Biological process	-
PIGR	5284	polymeric immunoglobulin receptor	detection of chemical stimulus involved in sensory perception of bitter taste	Biological process	24248522
OR51B6	390058	olfactory receptor, family 51, subfamily B, member 6	detection of chemical stimulus involved in sensory perception of smell	Biological process	11121057
FCMR	9214	Fc fragment of IgM receptor	extracellular region	Cellular component	-
LILRA5	353514	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5	extracellular exosome	Cellular component	23376485
CLDN3	1365	claudin 3	extracellular exosome	Cellular component	23376485
GALK1	2584	galactokinase 1	galactitol metabolic process	Biological process	-
FRZB	2487	frizzled-related protein	negative regulation of cartilage development	Biological process	-
CSRP1	1465	cysteine and glycine-rich protein 1	extracellular exosome	Cellular component	19056867
POLB	5423	polymerase (DNA directed), beta	microtubule binding	Molecular function	15725623
RBM22	55696	RNA binding motif protein 22	mRNA cis splicing, via spliceosome	Biological process	22246180
NOG	9241	noggin	protein binding	Molecular function	19804412
AQP9	366	aquaporin 9	water transmembrane transporter activity	Molecular function	9733774
EXOC2	55770	exocyst complex component 2	intracellular membrane-bounded organelle	Cellular component	-
APC	324	adenomatous polyposis coli	negative regulation of cell proliferation	Biological process	8521819
CROCC	9696	ciliary rootlet coiled-coil, rootletin	extracellular exosome	Cellular component	19056867
SCO1	6341	SCO1 cytochrome c oxidase assembly protein	copper ion transport	Biological process	-
INPP5K	51763	inositol polyphosphate-5-phosphatase K	negative regulation of MAP kinase activity	Biological process	12556481
ADI1	55256	acireductone dioxygenase 1	protein binding	Molecular function	14718544
BRD1	23774	bromodomain containing 1	histone binding	Molecular function	21880731
ELMO2	63916	engulfment and cell motility 2	cytoskeleton organization	Biological process	-
SLC4A9	83697	solute carrier family 4, sodium bicarbonate cotransporter, member 9	integral component of plasma membrane	Cellular component	-
ANKRD54	129138	ankyrin repeat domain 54	positive regulation of erythrocyte differentiation	Biological process	-
IDH1	3417	isocitrate dehydrogenase 1 (NADP+), soluble	glyoxylate cycle	Biological process	-
NES	10763	nestin	embryonic camera-type eye development	Biological process	-
GBP6	163351	guanylate binding protein family, member 6	cellular response to interferon-gamma	Biological process	-
ALDH3B1	221	aldehyde dehydrogenase 3 family, member B1	alcohol metabolic process	Biological process	7828891
NCS1	23413	neuronal calcium sensor 1	dendrite	Cellular component	-
AQP2	359	aquaporin 2 (collecting duct)	renal water transport	Biological process	-
KIF18B	146909	kinesin family member 18B	metabolic process	Biological process	-
DDX59	83479	DEAD (Asp-Glu-Ala-Asp) box polypeptide 59	RNA binding	Molecular function	-
ATN1	1822	atrophin 1	perinuclear region of cytoplasm	Cellular component	-
BRCA2	675	breast cancer 2, early onset	brain development	Biological process	-
RB1CC1	9821	RB1-inducible coiled-coil 1	nuclear membrane	Cellular component	-
OR6Y1	391112	olfactory receptor, family 6, subfamily Y, member 1	G-protein coupled receptor signaling pathway	Biological process	-
MYH11	4629	myosin, heavy chain 11, smooth muscle	smooth muscle contractile fiber	Cellular component	-
NAB2	4665	NGFI-A binding protein 2 (EGR1 binding protein 2)	negative regulation of transcription from RNA polymerase III promoter	Biological process	8668170
CATSPER3	347732	cation channel, sperm associated 3	CatSper complex	Cellular component	-
PTPRO	5800	protein tyrosine phosphatase, receptor type, O	peptidyl-tyrosine dephosphorylation	Biological process	19233845
SPI1	6688	Spi-1 proto-oncogene	lymphoid progenitor cell differentiation	Biological process	-
NAT8L	339983	N-acetyltransferase 8-like (GCN5-related, putative)	metabolic process	Biological process	-
ARL4C	10123	ADP-ribosylation factor-like 4C	filopodium	Cellular component	-
IGHM	3507	immunoglobulin heavy constant mu	cell surface	Cellular component	22427638
RPA1	6117	replication protein A1, 70kDa	PML body	Cellular component	17959650
SLC39A6	25800	solute carrier family 39 (zinc transporter), member 6	plasma membrane	Cellular component	-
EFHC1	114327	EF-hand domain (C-terminal) containing 1	axoneme	Cellular component	-
UBE2V1	7335	ubiquitin-conjugating enzyme E2 variant 1	toll-like receptor TLR6:TLR2 signaling pathway	Biological process	-
ARSK	153642	arylsulfatase family, member K	post-translational protein modification	Biological process	-
ACAD11	84129	acyl-CoA dehydrogenase family, member 11	mitochondrial membrane	Cellular component	21237683
ACTL6A	86	actin-like 6A	DNA recombination	Biological process	-
MSH3	4437	mutS homolog 3	centromeric DNA binding	Molecular function	-
IKBKE	9641	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	immune response	Biological process	10421793
TBX20	57057	T-box 20	nucleus	Cellular component	-
PLSCR1	5359	phospholipid scramblase 1	cytosol	Cellular component	17712045
PCBP1	5093	poly(rC) binding protein 1	protein binding	Molecular function	16713569
OR51G1	79324	olfactory receptor, family 51, subfamily G, member 1 (gene/pseudogene)	olfactory receptor activity	Molecular function	-
SERPINF1	5176	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1	short-term memory	Biological process	-
CRELD1	78987	cysteine-rich with EGF-like domains 1	calcium ion binding	Molecular function	-
MILR1	284021	mast cell immunoglobulin-like receptor 1	mast cell degranulation	Biological process	-
FLOT1	10211	flotillin 1	protein homooligomerization	Biological process	21399631
PAXBP1	94104	PAX3 and PAX7 binding protein 1	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	-
MBNL1	4154	muscleblind-like splicing regulator 1	regulation of alternative mRNA splicing, via spliceosome	Biological process	-
CDK5	1020	cyclin-dependent kinase 5	phosphorylation	Biological process	20357208
CNGA1	1259	cyclic nucleotide gated channel alpha 1	phototransduction, visible light	Biological process	-
CALM1	801	calmodulin 1 (phosphorylase kinase, delta)	positive regulation of cyclic-nucleotide phosphodiesterase activity	Biological process	8631777
GSK3B	2932	glycogen synthase kinase 3 beta	ionotropic glutamate receptor binding	Molecular function	-
DIEXF	27042	digestive organ expansion factor homolog (zebrafish)	multicellular organismal development	Biological process	-
CYP2E1	1571	cytochrome P450, family 2, subfamily E, polypeptide 1	epoxygenase P450 pathway	Biological process	-
DLG3	1741	discs, large homolog 3 (Drosophila)	receptor clustering	Biological process	-
RETN	56729	resistin	positive regulation of smooth muscle cell proliferation	Biological process	-
EXOSC1	51013	exosome component 1	RNA binding	Molecular function	11812149
IL26	55801	interleukin 26	inflammatory response	Biological process	-
BECN1	8678	beclin 1, autophagy related	beta-amyloid metabolic process	Biological process	-
BARHL1	56751	BarH-like homeobox 1	midbrain development	Biological process	-
STAT2	6773	signal transducer and activator of transcription 2, 113kDa	sequence-specific DNA binding transcription factor activity	Molecular function	-
ZFP2	80108	ZFP2 zinc finger protein	nucleus	Cellular component	-
CNR2	1269	cannabinoid receptor 2 (macrophage)	extrinsic component of cytoplasmic side of plasma membrane	Cellular component	-
HCN4	10021	hyperpolarization activated cyclic nucleotide gated potassium channel 4	muscle contraction	Biological process	10228147
GSK3B	2932	glycogen synthase kinase 3 beta	positive regulation of protein catabolic process	Biological process	16188939
VDAC1	7416	voltage-dependent anion channel 1	behavioral fear response	Biological process	-
ESD	2098	esterase D	hydrolase activity, acting on ester bonds	Molecular function	19126594
BTG1	694	B-cell translocation gene 1, anti-proliferative	positive regulation of angiogenesis	Biological process	15033446
STAMBP	10617	STAM binding protein	negative regulation of phosphatidylinositol 3-kinase signaling	Biological process	23542699
DNAH9	1770	dynein, axonemal, heavy chain 9	microtubule motor activity	Molecular function	-
MYF6	4618	myogenic factor 6 (herculin)	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
ADRA1A	148	adrenoceptor alpha 1A	activation of phospholipase C activity	Biological process	-
CTSF	8722	cathepsin F	proteolysis involved in cellular protein catabolic process	Biological process	-
AHCY	191	adenosylhomocysteinase	cytoplasm	Cellular component	-
SETMAR	6419	SET domain and mariner transposase fusion gene	site of double-strand break	Cellular component	22231448
SV2C	22987	synaptic vesicle glycoprotein 2C	neurotransmitter transport	Biological process	-
PLCD1	5333	phospholipase C, delta 1	intracellular signal transduction	Biological process	-
OR2M2	391194	olfactory receptor, family 2, subfamily M, member 2	plasma membrane	Cellular component	-
TGFB3	7043	transforming growth factor, beta 3	platelet alpha granule lumen	Cellular component	-
ZFAND5	7763	zinc finger, AN1-type domain 5	cellular_component	Cellular component	-
CARF	79800	calcium responsive transcription factor	positive regulation of transcription from RNA polymerase II promoter in response to calcium ion	Biological process	11832226
TWIST1	7291	twist family bHLH transcription factor 1	negative regulation of histone acetylation	Biological process	-
CDK1	983	cyclin-dependent kinase 1	protein kinase activity	Molecular function	22854038
POLR2H	5437	polymerase (RNA) II (DNA directed) polypeptide H	transcription-coupled nucleotide-excision repair	Biological process	-
Sep-04	5414	septin 4	cell cycle	Biological process	-
PLCB1	23236	phospholipase C, beta 1 (phosphoinositide-specific)	regulation of fertilization	Biological process	-
ZCWPW1	55063	zinc finger, CW type with PWWP domain 1	zinc ion binding	Molecular function	-
CACNB4	785	calcium channel, voltage-dependent, beta 4 subunit	thymus development	Biological process	-
CYP1B1	1545	cytochrome P450, family 1, subfamily B, polypeptide 1	arachidonic acid metabolic process	Biological process	-
IFNL3	282617	interferon, lambda 3	negative regulation of viral genome replication	Biological process	-
CNOT2	4848	CCR4-NOT transcription complex, subunit 2	protein binding	Molecular function	10637334
FXN	2395	frataxin	positive regulation of transferase activity	Biological process	18160053
CALR	811	calreticulin	sequestering of calcium ion	Biological process	15474971
DNASE1L1	1774	deoxyribonuclease I-like 1	DNA metabolic process	Biological process	9205125
KLRC4-KLRK1	100528032	KLRC4-KLRK1 readthrough	carbohydrate binding	Molecular function	-
LOC440434	440434	aminopeptidase puromycin sensitive pseudogene	extracellular exosome	Cellular component	23533145
IGHG1	3500	immunoglobulin heavy constant gamma 1 (G1m marker)	Fc-gamma receptor signaling pathway involved in phagocytosis	Biological process	-
ZNF322	79692	zinc finger protein 322	nucleus	Cellular component	-
BSPH1	100131137	binder of sperm protein homolog 1	cell surface	Cellular component	-
CREB3	10488	cAMP responsive element binding protein 3	sequence-specific DNA binding transcription factor activity	Molecular function	10675342
TBCA	6902	tubulin folding cofactor A	tubulin complex assembly	Biological process	-
IGLC2	3538	immunoglobulin lambda constant 2 (Kern-Oz- marker)	Fc-epsilon receptor signaling pathway	Biological process	-
CLEC4F	165530	C-type lectin domain family 4, member F	endocytosis	Biological process	-
MIF	4282	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	protein binding	Molecular function	12681488
ADIPOQ	9370	adiponectin, C1Q and collagen domain containing	positive regulation of cAMP-dependent protein kinase activity	Biological process	18431508
OR5J2	282775	olfactory receptor, family 5, subfamily J, member 2	odorant binding	Molecular function	-
LRP3	4037	low density lipoprotein receptor-related protein 3	receptor-mediated endocytosis	Biological process	9693042
OR2Z1	284383	olfactory receptor, family 2, subfamily Z, member 1	plasma membrane	Cellular component	-
COQ4	51117	coenzyme Q4	ubiquinone biosynthetic process	Biological process	-
KIF20A	10112	kinesin family member 20A	vesicle-mediated transport	Biological process	9438855
MAGEA2B	266740	melanoma antigen family A2B	signal transduction by p53 class mediator	Biological process	16847267
WNT3A	89780	wingless-type MMTV integration site family, member 3A	positive regulation of transcription, DNA-templated	Biological process	-
CCDC136	64753	coiled-coil domain containing 136	mitochondrion	Cellular component	-
RAB38	23682	RAB38, member RAS oncogene family	platelet dense granule organization	Biological process	-
SEPW1	6415	selenoprotein W, 1	selenium binding	Molecular function	-
CBX4	8535	chromobox homolog 4	protein sumoylation	Biological process	-
KAT2A	2648	K(lysine) acetyltransferase 2A	H3 histone acetyltransferase activity	Molecular function	18838386
ACE2	59272	angiotensin I converting enzyme 2	receptor biosynthetic process	Biological process	18258853
TCFL5	10732	transcription factor-like 5 (basic helix-loop-helix)	nucleus	Cellular component	9763657
NF1	4763	neurofibromin 1	nucleolus	Cellular component	-
SMARCC2	6601	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	SWI/SNF complex	Cellular component	10078207
C19orf80	55908	chromosome 19 open reading frame 80	fat cell differentiation	Biological process	-
IFNA10	3446	interferon, alpha 10	positive regulation of peptidyl-serine phosphorylation of STAT protein	Biological process	-
LSM1	27257	LSM1, U6 small nuclear RNA associated	protein binding	Molecular function	15231747
SYCP3	50511	synaptonemal complex protein 3	spermatid development	Biological process	-
PTGER3	5733	prostaglandin E receptor 3 (subtype EP3)	bicarbonate transport	Biological process	-
EZH2	2146	enhancer of zeste 2 polycomb repressive complex 2 subunit	chromatin binding	Molecular function	20154697
MFSD7	84179	major facilitator superfamily domain containing 7	integral component of membrane	Cellular component	-
GPX7	2882	glutathione peroxidase 7	response to reactive oxygen species	Biological process	-
SHMT1	6470	serine hydroxymethyltransferase 1 (soluble)	extracellular exosome	Cellular component	19056867
INPP4B	8821	inositol polyphosphate-4-phosphatase, type II, 105kDa	phosphatidylinositol trisphosphate phosphatase activity	Molecular function	-
SELPLG	6404	selectin P ligand	uropod	Cellular component	21696602
RPS14	6208	ribosomal protein S14	cellular protein metabolic process	Biological process	-
EPO	2056	erythropoietin	erythropoietin receptor binding	Molecular function	-
ADGRL2	23266	adhesion G protein-coupled receptor L2	latrotoxin receptor activity	Molecular function	10030676
ATP5H	10476	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d	small molecule metabolic process	Biological process	-
ATG9B	285973	autophagy related 9B	cytoplasmic vesicle	Cellular component	-
OR52Z1	283110	olfactory receptor, family 52, subfamily Z, member 1 (gene/pseudogene)	G-protein coupled receptor signaling pathway	Biological process	-
SPINK5	11005	serine peptidase inhibitor, Kazal type 5	anagen	Biological process	12915442
IL1B	3553	interleukin 1, beta	cellular response to organic cyclic compound	Biological process	21147091
SLC22A23	63027	solute carrier family 22, member 23	protein binding	Molecular function	25416956
RCC2	55920	regulator of chromosome condensation 2	small GTPase mediated signal transduction	Biological process	-
PREPL	9581	prolyl endopeptidase-like	serine-type endopeptidase activity	Molecular function	-
HAUS6	54801	HAUS augmin-like complex, subunit 6	spindle	Cellular component	-
TUSC2	11334	tumor suppressor candidate 2	mitochondrion	Cellular component	-
ERVK13-1	100507321	endogenous retrovirus group K13, member 1	integral component of membrane	Cellular component	-
ASPSCR1	79058	alveolar soft part sarcoma chromosome region, candidate 1	cytosol	Cellular component	-
TTR	7276	transthyretin	transport	Biological process	10841549
DNASE1L2	1775	deoxyribonuclease I-like 2	DNA metabolic process	Biological process	9205125
SPTY2D1	144108	SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)	molecular_function	Molecular function	-
SNX20	124460	sorting nexin 20	protein transport	Biological process	-
MYO1G	64005	myosin IG	membrane	Cellular component	19946888
GREM1	26585	gremlin 1, DAN family BMP antagonist	regulation of epithelial to mesenchymal transition	Biological process	16816361
UCP3	7352	uncoupling protein 3 (mitochondrial, proton carrier)	transporter activity	Molecular function	9196039
LGALS1	3956	lectin, galactoside-binding, soluble, 1	T cell costimulation	Biological process	-
PSMD1	5707	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	Biological process	-
RAB29	8934	RAB29, member RAS oncogene family	perinuclear region of cytoplasm	Cellular component	-
MGAT5B	146664	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B	integral component of membrane	Cellular component	-
ZNF559-ZNF177	100529215	ZNF559-ZNF177 readthrough	transcription, DNA-templated	Biological process	-
RAB14	51552	RAB14, member RAS oncogene family	rough endoplasmic reticulum	Cellular component	-
SOCS3	9021	suppressor of cytokine signaling 3	negative regulation of protein kinase activity	Biological process	9266833
HPGD	3248	hydroxyprostaglandin dehydrogenase 15-(NAD)	oxidation-reduction process	Biological process	-
RAD51B	5890	RAD51 paralog B	DNA-dependent ATPase activity	Molecular function	12441335
PHB2	11331	prohibitin 2	mitochondrial outer membrane	Cellular component	17008324
PSMD4	5710	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	stimulatory C-type lectin receptor signaling pathway	Biological process	-
ZNF599	148103	zinc finger protein 599	transcription, DNA-templated	Biological process	-
DGKK	139189	diacylglycerol kinase, kappa	response to oxidative stress	Biological process	16210324
ZNRF1	84937	zinc and ring finger 1, E3 ubiquitin protein ligase	membrane	Cellular component	22797923
ZC4H2	55906	zinc finger, C4H2 domain containing	metal ion binding	Molecular function	-
RASGRP3	25780	RAS guanyl releasing protein 3 (calcium and DAG-regulated)	guanyl-nucleotide exchange factor activity	Molecular function	-
RAB27A	5873	RAB27A, member RAS oncogene family	dendrite	Cellular component	11266474
OR11H1	81061	olfactory receptor, family 11, subfamily H, member 1	olfactory receptor activity	Molecular function	-
CNR1	1268	cannabinoid receptor 1 (brain)	plasma membrane	Cellular component	-
GADD45A	1647	growth arrest and DNA-damage-inducible, alpha	centrosome cycle	Biological process	-
MEOX1	4222	mesenchyme homeobox 1	hematopoietic stem cell differentiation	Biological process	-
SV2B	9899	synaptic vesicle glycoprotein 2B	transmembrane transport	Biological process	-
VCL	7414	vinculin	protein complex	Cellular component	9700171
TNS2	23371	tensin 2	multicellular organismal homeostasis	Biological process	-
WISP1	8840	WNT1 inducible signaling pathway protein 1	cell adhesion	Biological process	-
CDK3	1018	cyclin-dependent kinase 3	regulation of cell cycle	Biological process	1639063
SNCG	6623	synuclein, gamma (breast cancer-specific protein 1)	extracellular exosome	Cellular component	19056867
FLVCR1	28982	feline leukemia virus subgroup C cellular receptor 1	mitochondrion	Cellular component	23187127
IMPAD1	54928	inositol monophosphatase domain containing 1	3'-nucleotidase activity	Molecular function	-
CAV1	857	caveolin 1, caveolae protein, 22kDa	calcium ion homeostasis	Biological process	-
PATE4	399968	prostate and testis expressed 4	response to wounding	Biological process	-
MYD88	4615	myeloid differentiation primary response 88	response to interleukin-1	Biological process	19281832
ANKRD11	29123	ankyrin repeat domain 11	skeletal system morphogenesis	Biological process	21782149
SSX1	6756	synovial sarcoma, X breakpoint 1	negative regulation of nucleic acid-templated transcription	Biological process	10072425
NUFIP1	26747	nuclear fragile X mental retardation protein interacting protein 1	protein binding	Molecular function	10556305
HIST1H4B	8366	histone cluster 1, H4b	poly(A) RNA binding	Molecular function	22658674
CCL2	6347	chemokine (C-C motif) ligand 2	negative regulation of natural killer cell chemotaxis	Biological process	7545673
DDX5	1655	DEAD (Asp-Glu-Ala-Asp) box helicase 5	negative regulation of transcription from RNA polymerase II promoter	Biological process	15298701
SUPT5H	6829	suppressor of Ty 5 homolog (S. cerevisiae)	transcription elongation from RNA polymerase II promoter	Biological process	-
CD247	919	CD247 molecule	cytoplasm	Cellular component	11390434
MAP4	4134	microtubule-associated protein 4	extracellular exosome	Cellular component	23376485
EPX	8288	eosinophil peroxidase	negative regulation of interleukin-5 production	Biological process	-
CCL21	6366	chemokine (C-C motif) ligand 21	immunological synapse formation	Biological process	-
CD3D	915	CD3d molecule, delta (CD3-TCR complex)	T cell receptor signaling pathway	Biological process	-
POU5F1B	5462	POU class 5 homeobox 1B	nucleus	Cellular component	-
NCR3LG1	374383	natural killer cell cytotoxicity receptor 3 ligand 1	integral component of membrane	Cellular component	-
PML	5371	promyelocytic leukemia	nucleus	Cellular component	16778193
TYSND1	219743	trypsin domain containing 1	identical protein binding	Molecular function	22002062
CDC14A	8556	cell division cycle 14A	phosphoprotein phosphatase activity	Molecular function	9367992
GSTA3	2940	glutathione S-transferase alpha 3	xenobiotic metabolic process	Biological process	-
ARHGAP1	392	Rho GTPase activating protein 1	Rho protein signal transduction	Biological process	8253717
RGCC	28984	regulator of cell cycle	positive regulation of extracellular matrix constituent secretion	Biological process	19158077
NLRP3	114548	NLR family, pyrin domain containing 3	interleukin-1 secretion	Biological process	-
SLC6A8	6535	solute carrier family 6 (neurotransmitter transporter), member 8	creatine:sodium symporter activity	Molecular function	-
KPNA6	23633	karyopherin alpha 6 (importin alpha 7)	NLS-bearing protein import into nucleus	Biological process	9395085
ABL1	25	ABL proto-oncogene 1, non-receptor tyrosine kinase	regulation of actin cytoskeleton reorganization	Biological process	20841568
HPCAL1	3241	hippocalcin-like 1	extracellular exosome	Cellular component	23376485
HRASLS	57110	HRAS-like suppressor	transferase activity	Molecular function	-
GLRA2	2742	glycine receptor, alpha 2	chloride channel complex	Cellular component	-
RAP2B	5912	RAP2B, member of RAS oncogene family	cell-cell contact zone	Cellular component	23885123
SORD	6652	sorbitol dehydrogenase	zinc ion binding	Molecular function	-
ACOT8	10005	acyl-CoA thioesterase 8	fatty acid beta-oxidation using acyl-CoA oxidase	Biological process	-
TRIP6	7205	thyroid hormone receptor interactor 6	regulation of transcription, DNA-templated	Biological process	-
CBX5	23468	chromobox homolog 5	transcriptional repressor complex	Cellular component	-
DRD1	1812	dopamine receptor D1	phospholipase C-activating dopamine receptor signaling pathway	Biological process	17194762
GDF7	151449	growth differentiation factor 7	regulation of apoptotic process	Biological process	-
FMR1	2332	fragile X mental retardation 1	synapse	Cellular component	-
ITGB1	3688	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	glycoprotein binding	Molecular function	-
ADCY3	109	adenylate cyclase 3	water transport	Biological process	-
HMGA1	3159	high mobility group AT-hook 1	transcription factor complex	Cellular component	10428834
WDR55	54853	WD repeat domain 55	RNA metabolic process	Biological process	-
HBD	3045	hemoglobin, delta	oxygen transport	Biological process	-
NDUFS1	4719	NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)	mitochondrion	Cellular component	-
C4A	720	complement component 4A (Rodgers blood group)	plasma membrane	Cellular component	-
SUFU	51684	suppressor of fused homolog (Drosophila)	negative regulation of osteoblast differentiation	Biological process	11001584
CEP68	23177	centrosomal protein 68kDa	centrosome organization	Biological process	18042621
RPS16	6217	ribosomal protein S16	viral life cycle	Biological process	-
NRF1	4899	nuclear respiratory factor 1	cytoplasm	Cellular component	-
JAG1	182	jagged 1	response to muramyl dipeptide	Biological process	-
TAB1	10454	TGF-beta activated kinase 1/MAP3K7 binding protein 1	cytosol	Cellular component	-
ZYX	7791	zyxin	integral component of plasma membrane	Cellular component	8940160
GALNT8	26290	polypeptide N-acetylgalactosaminyltransferase 8	carbohydrate binding	Molecular function	-
TJP2	9414	tight junction protein 2	cytoplasm	Cellular component	-
SLC1A6	6511	solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6	transmembrane transport	Biological process	-
ZC3H12A	80149	zinc finger CCCH-type containing 12A	cytoplasm	Cellular component	-
CDC42EP5	148170	CDC42 effector protein (Rho GTPase binding) 5	GTP-Rho binding	Molecular function	11035016
PRKCB	5579	protein kinase C, beta	ATP binding	Molecular function	-
HSDL2	84263	hydroxysteroid dehydrogenase like 2	oxidoreductase activity	Molecular function	-
RPS6KB1	6198	ribosomal protein S6 kinase, 70kDa, polypeptide 1	skeletal muscle contraction	Biological process	-
IL16	3603	interleukin 16	leukocyte chemotaxis	Biological process	-
SOD3	6649	superoxide dismutase 3, extracellular	nucleus	Cellular component	-
SLC16A14	151473	solute carrier family 16, member 14	symporter activity	Molecular function	-
PGLYRP1	8993	peptidoglycan recognition protein 1	defense response to Gram-positive bacterium	Biological process	11461926
SYNPR	132204	synaptoporin	neuron projection	Cellular component	-
ATP5L	10632	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G	small molecule metabolic process	Biological process	-
TRPC5	7224	transient receptor potential cation channel, subfamily C, member 5	calcium channel complex	Cellular component	20164195
TBX3	6926	T-box 3	positive regulation of cell proliferation	Biological process	11689487
PRKCD	5580	protein kinase C, delta	negative regulation of inflammatory response	Biological process	19279008
TAF1C	9013	TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa	transcription from RNA polymerase I promoter	Biological process	-
LTBP3	4054	latent transforming growth factor beta binding protein 3	transforming growth factor beta receptor signaling pathway	Biological process	-
HSF2	3298	heat shock transcription factor 2	RNA polymerase II regulatory region sequence-specific DNA binding	Molecular function	10561509
RSRC1	51319	arginine/serine-rich coiled-coil 1	response to antibiotic	Biological process	-
LYPD3	27076	LY6/PLAUR domain containing 3	laminin binding	Molecular function	-
GRIA1	2890	glutamate receptor, ionotropic, AMPA 1	postsynaptic membrane	Cellular component	-
POLR1B	84172	polymerase (RNA) I polypeptide B, 128kDa	transcription initiation from RNA polymerase I promoter	Biological process	-
DIAPH1	1729	diaphanous-related formin 1	profilin binding	Molecular function	-
SPI1	6688	Spi-1 proto-oncogene	hypermethylation of CpG island	Biological process	20139074
RBM15B	29890	RNA binding motif protein 15B	nucleotide binding	Molecular function	-
FANCI	55215	Fanconi anemia, complementation group I	DNA polymerase binding	Molecular function	19995904
CLPS	1208	colipase, pancreatic	phototransduction, visible light	Biological process	-
TNNC1	7134	troponin C type 1 (slow)	troponin T binding	Molecular function	15542288
ACVRL1	94	activin A receptor type II-like 1	receptor signaling protein serine/threonine kinase activity	Molecular function	-
SMURF1	57154	SMAD specific E3 ubiquitin protein ligase 1	ubiquitin-dependent SMAD protein catabolic process	Biological process	11278251
AVP	551	arginine vasopressin	grooming behavior	Biological process	-
TNFSF11	8600	tumor necrosis factor (ligand) superfamily, member 11	integral component of plasma membrane	Cellular component	9312132
MAGI2	9863	membrane associated guanylate kinase, WW and PDZ domain containing 2	cytoplasmic transport	Biological process	-
CCL2	6347	chemokine (C-C motif) ligand 2	MAPK cascade	Biological process	21147091
PLA2G1B	5319	phospholipase A2, group IB (pancreas)	phosphatidylglycerol acyl-chain remodeling	Biological process	-
HBE1	3046	hemoglobin, epsilon 1	blood microparticle	Cellular component	22516433
STUB1	10273	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase	DNA repair	Biological process	-
ADCK3	56997	aarF domain containing kinase 3	phosphorylation	Biological process	25498144
MFN1	55669	mitofusin 1	GTP binding	Molecular function	-
PLA2G2D	26279	phospholipase A2, group IID	extracellular region	Cellular component	-
ZP1	22917	zona pellucida glycoprotein 1 (sperm receptor)	multicellular organism reproduction	Biological process	-
SH3PXD2A	9644	SH3 and PX domains 2A	osteoclast fusion	Biological process	22584907
PLXNA4	91584	plexin A4	integral component of membrane	Cellular component	-
FKBP6	8468	FK506 binding protein 6, 36kDa	synaptonemal complex	Cellular component	-
RET	5979	ret proto-oncogene	neuron cell-cell adhesion	Biological process	21357690
CYS1	192668	cystin 1	organelle organization	Biological process	-
MAP2K4	6416	mitogen-activated protein kinase kinase 4	toll-like receptor TLR6:TLR2 signaling pathway	Biological process	-
FXYD3	5349	FXYD domain containing ion transport regulator 3	chloride transport	Biological process	7836447
RIPK1	8737	receptor (TNFRSF)-interacting serine-threonine kinase 1	cytosol	Cellular component	-
MOCS2	4338	molybdenum cofactor synthesis 2	identical protein binding	Molecular function	-
RPS27L	51065	ribosomal protein S27-like	translation activator activity	Molecular function	18056458
AR	367	androgen receptor	intracellular receptor signaling pathway	Biological process	17277772
CLEC14A	161198	C-type lectin domain family 14, member A	integral component of membrane	Cellular component	-
GOT2	2806	glutamic-oxaloacetic transaminase 2, mitochondrial	poly(A) RNA binding	Molecular function	22681889
SUGP2	10147	SURP and G patch domain containing 2	RNA splicing	Biological process	-
CLASP2	23122	cytoplasmic linker associated protein 2	axon guidance	Biological process	-
OR52I2	143502	olfactory receptor, family 52, subfamily I, member 2	G-protein coupled receptor signaling pathway	Biological process	-
FOXH1	8928	forkhead box H1	secondary heart field specification	Biological process	-
PPARG	5468	peroxisome proliferator-activated receptor gamma	response to lipid	Biological process	9568715
LRP6	4040	low density lipoprotein receptor-related protein 6	cytosol	Cellular component	-
HEBP1	50865	heme binding protein 1	heme binding	Molecular function	-
MAPK7	5598	mitogen-activated protein kinase 7	toll-like receptor 9 signaling pathway	Biological process	-
NCEH1	57552	neutral cholesterol ester hydrolase 1	endoplasmic reticulum	Cellular component	-
CALCRL	10203	calcitonin receptor-like	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	Biological process	7818539
TBCC	6903	tubulin folding cofactor C	microtubule	Cellular component	8706133
NFASC	23114	neurofascin	peripheral nervous system development	Biological process	-
TRIM5	85363	tripartite motif containing 5	protein binding	Molecular function	12878161
PRKAR1A	5573	protein kinase, cAMP-dependent, regulatory, type I, alpha	energy reserve metabolic process	Biological process	-
SORD	6652	sorbitol dehydrogenase	glucose metabolic process	Biological process	14965227
PPARG	5468	peroxisome proliferator-activated receptor gamma	glucose homeostasis	Biological process	10622252
CYP3A43	64816	cytochrome P450, family 3, subfamily A, polypeptide 43	oxidation-reduction process	Biological process	-
F3	2152	coagulation factor III (thromboplastin, tissue factor)	extracellular exosome	Cellular component	23376485
CLTC	1213	clathrin, heavy chain (Hc)	protein binding	Molecular function	12429846
ALAD	210	aminolevulinate dehydratase	nucleus	Cellular component	21630459
CENPE	1062	centromere protein E, 312kDa	microtubule cytoskeleton	Cellular component	-
PHOX2B	8929	paired-like homeobox 2b	cellular response to BMP stimulus	Biological process	-
CEP57	9702	centrosomal protein 57kDa	Golgi apparatus	Cellular component	10942595
CLN3	1201	ceroid-lipofuscinosis, neuronal 3	Golgi membrane	Cellular component	10191111
OR8H1	219469	olfactory receptor, family 8, subfamily H, member 1	odorant binding	Molecular function	-
NTRK2	4915	neurotrophic tyrosine kinase, receptor, type 2	positive regulation of peptidyl-serine phosphorylation	Biological process	-
GATA3	2625	GATA binding protein 3	axon guidance	Biological process	-
CDH9	1007	cadherin 9, type 2 (T1-cadherin)	integral component of membrane	Cellular component	-
LMF1	64788	lipase maturation factor 1	positive regulation of lipoprotein lipase activity	Biological process	-
ITGB1	3688	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	cell surface	Cellular component	1715889
NUDT6	11162	nudix (nucleoside diphosphate linked moiety X)-type motif 6	biological_process	Biological process	-
NKX1-1	54729	NK1 homeobox 1	nucleus	Cellular component	-
CLIC2	1193	chloride intracellular channel 2	signal transduction	Biological process	16130169
EIF2B1	1967	eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa	regulation of translational initiation	Biological process	-
SOCS4	122809	suppressor of cytokine signaling 4	protein kinase inhibitor activity	Molecular function	-
GRHL2	79977	grainyhead-like 2 (Drosophila)	intronic transcription regulatory region sequence-specific DNA binding	Molecular function	-
COL13A1	1305	collagen, type XIII, alpha 1	morphogenesis of a branching structure	Biological process	-
APLN	8862	apelin	positive regulation of corticotropin secretion	Biological process	-
HES6	55502	hes family bHLH transcription factor 6	nervous system development	Biological process	-
SERPINB13	5275	serpin peptidase inhibitor, clade B (ovalbumin), member 13	cysteine-type endopeptidase inhibitor activity	Molecular function	12809493
TEAD4	7004	TEA domain family member 4	DNA binding	Molecular function	-
KIF16B	55614	kinesin family member 16B	regulation of receptor recycling	Biological process	15882625
RRM2	6241	ribonucleotide reductase M2	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	Molecular function	1627826
AIPL1	23746	aryl hydrocarbon receptor interacting protein-like 1	regulation of cGMP metabolic process	Biological process	-
OR10A5	144124	olfactory receptor, family 10, subfamily A, member 5	plasma membrane	Cellular component	-
ERGIC3	51614	ERGIC and golgi 3	membrane	Cellular component	19946888
AP3B2	8120	adaptor-related protein complex 3, beta 2 subunit	anterograde axon cargo transport	Biological process	-
TIAM2	26230	T-cell lymphoma invasion and metastasis 2	positive regulation of apoptotic process	Biological process	-
GPIHBP1	338328	glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1	intracellular	Cellular component	20620994
NOXO1	124056	NADPH oxidase organizer 1	regulation of hydrogen peroxide metabolic process	Biological process	16636067
IL6	3569	interleukin 6	response to auditory stimulus	Biological process	-
MYO3B	140469	myosin IIIB	ATP binding	Molecular function	-
TEAD1	7003	TEA domain family member 1 (SV40 transcriptional enhancer factor)	nucleoplasm	Cellular component	-
GRIP1	23426	glutamate receptor interacting protein 1	endoplasmic reticulum	Cellular component	-
FBXW7	55294	F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase	regulation of transcription, DNA-templated	Biological process	-
ITPR1	3708	inositol 1,4,5-trisphosphate receptor, type 1	integral component of membrane	Cellular component	-
OR4K3	283617	olfactory receptor, family 4, subfamily K, member 3 (gene/pseudogene)	integral component of membrane	Cellular component	-
OR10A7	121364	olfactory receptor, family 10, subfamily A, member 7	G-protein coupled receptor signaling pathway	Biological process	-
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	layer formation in cerebral cortex	Biological process	-
BAX	581	BCL2-associated X protein	extrinsic apoptotic signaling pathway in absence of ligand	Biological process	-
KCNJ11	3767	potassium channel, inwardly rectifying subfamily J, member 11	cellular response to nicotine	Biological process	-
MSN	4478	moesin	positive regulation of gene expression	Biological process	23264465
OR5F1	338674	olfactory receptor, family 5, subfamily F, member 1	integral component of membrane	Cellular component	9787077
C1RL	51279	complement component 1, r subcomponent-like	proteolysis	Biological process	-
ZBTB18	10472	zinc finger and BTB domain containing 18	homeostasis of number of cells	Biological process	-
AFM	173	afamin	vitamin transport	Biological process	19046407
CSF3	1440	colony stimulating factor 3 (granulocyte)	positive regulation of peptidyl-serine phosphorylation	Biological process	23001182
MEOX2	4223	mesenchyme homeobox 2	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	17074759
ATF3	467	activating transcription factor 3	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance	Biological process	14685163
NCEH1	57552	neutral cholesterol ester hydrolase 1	carboxylic ester hydrolase activity	Molecular function	-
FOXC1	2296	forkhead box C1	blood vessel remodeling	Biological process	-
CDC42EP1	11135	CDC42 effector protein (Rho GTPase binding) 1	focal adhesion	Cellular component	21423176
PEX14	5195	peroxisomal biogenesis factor 14	negative regulation of sequence-specific DNA binding transcription factor activity	Biological process	11863372
ARF4	378	ADP-ribosylation factor 4	small GTPase mediated signal transduction	Biological process	-
BRCC3	79184	BRCA1/BRCA2-containing complex, subunit 3	ubiquitin-specific protease activity	Molecular function	19261746
PENK	5179	proenkephalin	behavioral fear response	Biological process	-
LEFTY2	7044	left-right determination factor 2	cell growth	Biological process	-
BDH1	622	3-hydroxybutyrate dehydrogenase, type 1	adipose tissue development	Biological process	-
OAS2	4939	2'-5'-oligoadenylate synthetase 2, 69/71kDa	response to virus	Biological process	21142819
ATM	472	ATM serine/threonine kinase	protein dimerization activity	Molecular function	15790808
GLS2	27165	glutaminase 2 (liver, mitochondrial)	positive regulation of protein targeting to mitochondrion	Biological process	24270810
RPL36	25873	ribosomal protein L36	translation	Biological process	-
CCNE2	9134	cyclin E2	G1/S transition of mitotic cell cycle	Biological process	-
NDC80	10403	NDC80 kinetochore complex component	structural constituent of cytoskeleton	Molecular function	-
AFAP1	60312	actin filament associated protein 1	actin binding	Molecular function	-
ZNF250	58500	zinc finger protein 250	DNA binding	Molecular function	-
TRIM54	57159	tripartite motif containing 54	signal transduction	Biological process	11243782
ZNF559-ZNF177	100529215	ZNF559-ZNF177 readthrough	blood microparticle	Cellular component	22516433
STAT3	6774	signal transducer and activator of transcription 3 (acute-phase response factor)	interleukin-6-mediated signaling pathway	Biological process	16835372
HPS3	84343	Hermansky-Pudlak syndrome 3	BLOC-2 complex	Cellular component	15030569
STX2	2054	syntaxin 2	response to hydroperoxide	Biological process	22226963
RPS26	6231	ribosomal protein S26	viral life cycle	Biological process	-
OR51V1	283111	olfactory receptor, family 51, subfamily V, member 1	G-protein coupled receptor activity	Molecular function	-
PYY	5697	peptide YY	regulation of appetite	Biological process	-
SLC35B3	51000	solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3	mitochondrion	Cellular component	-
VKORC1	79001	vitamin K epoxide reductase complex, subunit 1	peptidyl-glutamic acid carboxylation	Biological process	-
GALNT14	79623	polypeptide N-acetylgalactosaminyltransferase 14	Golgi membrane	Cellular component	-
HSPA1A	3303	heat shock 70kDa protein 1A	protein refolding	Biological process	15603737
DRD5	1816	dopamine receptor D5	integral component of plasma membrane	Cellular component	9457173
CPEB3	22849	cytoplasmic polyadenylation element binding protein 3	translation	Biological process	-
SETD2	29072	SET domain containing 2	mismatch repair	Biological process	23622243
FAT2	2196	FAT atypical cadherin 2	calcium ion binding	Molecular function	-
LYN	4067	LYN proto-oncogene, Src family tyrosine kinase	receptor binding	Molecular function	-
INS	3630	insulin	regulation of protein localization	Biological process	14615391
NUDT21	11051	nudix (nucleoside diphosphate linked moiety X)-type motif 21	AU-rich element binding	Molecular function	20479262
CRTC1	23373	CREB regulated transcription coactivator 1	memory	Biological process	-
BLVRA	644	biliverdin reductase A	zinc ion binding	Molecular function	-
HAUS5	23354	HAUS augmin-like complex, subunit 5	centrosome organization	Biological process	19427217
ZBP1	81030	Z-DNA binding protein 1	biological_process	Biological process	-
REM1	28954	RAS (RAD and GEM)-like GTP-binding 1	GTP binding	Molecular function	-
ADRB2	154	adrenoceptor beta 2, surface	nucleus	Cellular component	-
CNOT8	9337	CCR4-NOT transcription complex, subunit 8	cytosol	Cellular component	-
TSG101	7251	tumor susceptibility 101	regulation of MAP kinase activity	Biological process	17714434
HDGFRP2	84717	hepatoma-derived growth factor-related protein 2	nucleoplasm	Cellular component	-
ZP3	7784	zona pellucida glycoprotein 3 (sperm receptor)	negative regulation of binding of sperm to zona pellucida	Biological process	18667750
MRPS35	60488	mitochondrial ribosomal protein S35	poly(A) RNA binding	Molecular function	22681889
MAP2K4	6416	mitogen-activated protein kinase kinase 4	intracellular	Cellular component	-
SLC6A2	6530	solute carrier family 6 (neurotransmitter transporter), member 2	transmembrane transport	Biological process	-
APEX1	328	APEX nuclease (multifunctional DNA repair enzyme) 1	positive regulation of DNA repair	Biological process	9207062
PAX5	5079	paired box 5	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	-
GCDH	2639	glutaryl-CoA dehydrogenase	fatty acid oxidation	Biological process	-
MYOD1	4654	myogenic differentiation 1	nuclear hormone receptor binding	Molecular function	9862959
CLDN8	9073	claudin 8	bicellular tight junction	Cellular component	-
C1QBP	708	complement component 1, q subcomponent binding protein	cytoplasm	Cellular component	-
XBP1	7494	X-box binding protein 1	positive regulation of T cell differentiation	Biological process	11460154
CFLAR	8837	CASP8 and FADD-like apoptosis regulator	viral process	Biological process	-
WWTR1	25937	WW domain containing transcription regulator 1	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
PLA2G2C	391013	phospholipase A2, group IIC	phospholipase A2 activity	Molecular function	-
OS9	10956	osteosarcoma amplified 9, endoplasmic reticulum lectin	Hrd1p ubiquitin ligase complex	Cellular component	18502753
SLC11A2	4891	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2	inorganic cation transmembrane transporter activity	Molecular function	12475959
ADD1	118	adducin 1 (alpha)	spectrin binding	Molecular function	7642559
SFN	2810	stratifin	keratinization	Biological process	-
PTK2B	2185	protein tyrosine kinase 2 beta	cytosol	Cellular component	-
TGM1	7051	transglutaminase 1	protein binding	Molecular function	10066784
SLC12A7	10723	solute carrier family 12 (potassium/chloride transporter), member 7	protein kinase binding	Molecular function	24393035
GNPAT	8443	glyceronephosphate O-acyltransferase	cerebellum morphogenesis	Biological process	-
SNRPD3	6634	small nuclear ribonucleoprotein D3 polypeptide 18kDa	cytosol	Cellular component	-
LRRC10	376132	leucine rich repeat containing 10	actin binding	Molecular function	-
CNGA3	1261	cyclic nucleotide gated channel alpha 3	response to corticosteroid	Biological process	-
YWHAE	7531	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon	axon	Cellular component	-
PSMC1	5700	proteasome (prosome, macropain) 26S subunit, ATPase, 1	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition	Biological process	-
TIMM13	26517	translocase of inner mitochondrial membrane 13 homolog (yeast)	zinc ion binding	Molecular function	10552927
FADS2	9415	fatty acid desaturase 2	linoleic acid metabolic process	Biological process	-
NKX3-1	4824	NK3 homeobox 1	negative regulation of epithelial cell proliferation	Biological process	-
CFTR	1080	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	positive regulation of voltage-gated chloride channel activity	Biological process	22006324
POLR3H	171568	polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)	RNA polymerase III activity	Molecular function	-
PDSS1	23590	prenyl (decaprenyl) diphosphate synthase, subunit 1	ubiquinone biosynthetic process	Biological process	-
RGS11	8786	regulator of G-protein signaling 11	protein complex	Cellular component	18468998
IGF1	3479	insulin-like growth factor 1 (somatomedin C)	positive regulation of MAPK cascade	Biological process	19654000
DYNC2LI1	51626	dynein, cytoplasmic 2, light intermediate chain 1	metabolic process	Biological process	-
HIST1H1D	3007	histone cluster 1, H1d	nucleosome	Cellular component	-
TRIM9	114088	tripartite motif containing 9	cytoplasm	Cellular component	11331580
AKR1B10	57016	aldo-keto reductase family 1, member B10 (aldose reductase)	cytosol	Cellular component	-
RPL6	6128	ribosomal protein L6	poly(A) RNA binding	Molecular function	22658674
HMGN2	3151	high mobility group nucleosomal binding domain 2	nucleus	Cellular component	-
GLI2	2736	GLI family zinc finger 2	positive regulation of neuron differentiation	Biological process	-
ADAD2	161931	adenosine deaminase domain containing 2	RNA binding	Molecular function	-
BCAR1	9564	breast cancer anti-estrogen resistance 1	actin cytoskeleton	Cellular component	-
SCNN1A	6337	sodium channel, non voltage gated 1 alpha subunit	transmembrane transport	Biological process	-
PYCARD	29108	PYD and CARD domain containing	positive regulation of cysteine-type endopeptidase activity	Biological process	19158676
HEPACAM2	253012	HEPACAM family member 2	Golgi membrane	Cellular component	-
PATZ1	23598	POZ (BTB) and AT hook containing zinc finger 1	cytoplasm	Cellular component	-
RUVBL1	8607	RuvB-like AAA ATPase 1	cytoplasm	Cellular component	-
BMP7	655	bone morphogenetic protein 7	regulation of pathway-restricted SMAD protein phosphorylation	Biological process	16049014
ST6GAL2	84620	ST6 beta-galactosamide alpha-2,6-sialyltranferase 2	oligosaccharide metabolic process	Biological process	12235148
ZFP36L1	677	ZFP36 ring finger protein-like 1	heart development	Biological process	-
SLIT2	9353	slit homolog 2 (Drosophila)	branching morphogenesis of an epithelial tube	Biological process	19005219
ZNF703	80139	zinc finger protein 703	regulation of transcription, DNA-templated	Biological process	21328542
SMARCA4	6597	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	extracellular matrix organization	Biological process	-
CAPN10	11132	calpain 10	type B pancreatic cell apoptotic process	Biological process	15044459
AVPR1A	552	arginine vasopressin receptor 1A	cytosol	Cellular component	8106369
SYP	6855	synaptophysin	regulation of opioid receptor signaling pathway	Biological process	-
PDGFA	5154	platelet-derived growth factor alpha polypeptide	regulation of peptidyl-tyrosine phosphorylation	Biological process	-
USE1	55850	unconventional SNARE in the ER 1 homolog (S. cerevisiae)	ER to Golgi vesicle-mediated transport	Biological process	16354670
WBP11	51729	WW domain binding protein 11	RNA splicing	Biological process	-
PPARD	5467	peroxisome proliferator-activated receptor delta	negative regulation of transcription, DNA-templated	Biological process	-
HNF4A	3172	hepatocyte nuclear factor 4, alpha	cytoplasm	Cellular component	14563941
LAT	27040	linker for activation of T cells	Fc-epsilon receptor signaling pathway	Biological process	-
PIK3C2A	5286	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha	platelet-derived growth factor receptor signaling pathway	Biological process	17371240
HMGA2	8091	high mobility group AT-hook 2	nucleoplasm	Cellular component	-
TFB2M	64216	transcription factor B2, mitochondrial	organelle organization	Biological process	-
SGCZ	137868	sarcoglycan, zeta	sarcolemma	Cellular component	-
RAB26	25837	RAB26, member RAS oncogene family	endosome	Cellular component	-
C2orf42	54980	chromosome 2 open reading frame 42	nucleus	Cellular component	-
GABRB1	2560	gamma-aminobutyric acid (GABA) A receptor, beta 1	GABA-A receptor activity	Molecular function	-
COPE	11316	coatomer protein complex, subunit epsilon	retrograde vesicle-mediated transport, Golgi to ER	Biological process	-
MTPN	136319	myotrophin	positive regulation of cell growth	Biological process	-
DGKD	8527	diacylglycerol kinase, delta 130kDa	metal ion binding	Molecular function	-
RAB7A	7879	RAB7A, member RAS oncogene family	early endosome to late endosome transport	Biological process	14617358
PPP1R9B	84687	protein phosphatase 1, regulatory subunit 9B	filopodium	Cellular component	19151759
PDE1B	5153	phosphodiesterase 1B, calmodulin-dependent	monocyte differentiation	Biological process	14687666
SOX6	55553	SRY (sex determining region Y)-box 6	nucleoplasm	Cellular component	-
P4HB	5034	prolyl 4-hydroxylase, beta polypeptide	enzyme binding	Molecular function	-
HMGA1	3159	high mobility group AT-hook 1	nucleoplasm	Cellular component	-
ATP1A4	480	ATPase, Na+/K+ transporting, alpha 4 polypeptide	ATP hydrolysis coupled proton transport	Biological process	7809153
ZNF398	57541	zinc finger protein 398	transcription, DNA-templated	Biological process	-
S1PR5	53637	sphingosine-1-phosphate receptor 5	sphingosine-1-phosphate receptor activity	Molecular function	-
PSD	5662	pleckstrin and Sec7 domain containing	signal transduction	Biological process	9417912
MTPAP	55149	mitochondrial poly(A) polymerase	mRNA polyadenylation	Biological process	21292163
ATP6V1A	523	ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A	transmembrane transport	Biological process	-
MAML2	84441	mastermind-like 2 (Drosophila)	gene expression	Biological process	-
OR11A1	26531	olfactory receptor, family 11, subfamily A, member 1	olfactory receptor activity	Molecular function	-
PPP2R1A	5518	protein phosphatase 2, regulatory subunit A, alpha	organelle organization	Biological process	-
RPS20	6224	ribosomal protein S20	cytoplasm	Cellular component	-
BRCA1	672	breast cancer 1, early onset	negative regulation of reactive oxygen species metabolic process	Biological process	23415688
SRP19	6728	signal recognition particle 19kDa	gene expression	Biological process	-
TBX19	9095	T-box 19	enhancer sequence-specific DNA binding	Molecular function	-
SLC26A8	116369	solute carrier family 26 (anion exchanger), member 8	integral component of membrane	Cellular component	-
DDIT3	1649	DNA-damage-inducible transcript 3	ER overload response	Biological process	-
TMTC3	160418	transmembrane and tetratricopeptide repeat containing 3	muscle fiber development	Biological process	-
SRP68	6730	signal recognition particle 68kDa	cytoplasm	Cellular component	-
PAK1IP1	55003	PAK1 interacting protein 1	palate development	Biological process	-
AGT	183	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	positive regulation of cholesterol esterification	Biological process	18971559
DTD1	92675	D-tyrosyl-tRNA deacylase 1	nucleus	Cellular component	-
SOX17	64321	SRY (sex determining region Y)-box 17	transcription coactivator activity	Molecular function	-
FNBP1L	54874	formin binding protein 1-like	plasma membrane	Cellular component	-
CACNA1A	773	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	energy reserve metabolic process	Biological process	-
PIWIL1	9271	piwi-like RNA-mediated gene silencing 1	chromatoid body	Cellular component	-
RCC1	1104	regulator of chromosome condensation 1	cytoplasm	Cellular component	17435751
NOTCH1	4851	notch 1	branching morphogenesis of an epithelial tube	Biological process	-
EEF1E1	9521	eukaryotic translation elongation factor 1 epsilon 1	cytosol	Cellular component	-
CLTA	1211	clathrin, light chain A	clathrin complex	Cellular component	4066749
TMEM17	200728	transmembrane protein 17	TCTN-B9D complex	Cellular component	-
RARG	5916	retinoic acid receptor, gamma	regulation of myelination	Biological process	-
USP6	9098	ubiquitin specific peptidase 6	plasma membrane	Cellular component	12612085
C5orf30	90355	chromosome 5 open reading frame 30	protein transport	Biological process	-
POR	5447	P450 (cytochrome) oxidoreductase	nitric oxide catabolic process	Biological process	-
NLRP3	114548	NLR family, pyrin domain containing 3	positive regulation of NF-kappaB transcription factor activity	Biological process	19158675
FRS2	10818	fibroblast growth factor receptor substrate 2	fibroblast growth factor receptor binding	Molecular function	9660748
STK25	10494	serine/threonine kinase 25	positive regulation of stress-activated MAPK cascade	Biological process	22652780
RRAS	6237	related RAS viral (r-ras) oncogene homolog	metabolic process	Biological process	3098437
SERPINE1	5054	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	negative regulation of wound healing	Biological process	8837777
FAU	2197	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed	antibacterial humoral response	Biological process	12860195
RBM34	23029	RNA binding motif protein 34	nucleolus	Cellular component	-
PITPNA	5306	phosphatidylinositol transfer protein, alpha	axon guidance	Biological process	-
C1orf27	54953	chromosome 1 open reading frame 27	oxidation-reduction process	Biological process	-
LTF	4057	lactotransferrin	negative regulation of apoptotic process	Biological process	-
PKD1L3	342372	polycystic kidney disease 1-like 3	calcium ion transmembrane transport	Biological process	-
ZCCHC8	55596	zinc finger, CCHC domain containing 8	nucleus	Cellular component	-
MTRNR2L8	100463486	MT-RNR2-like 8	extracellular region	Cellular component	-
UBE2G2	7327	ubiquitin-conjugating enzyme E2G 2	ubiquitin-protein transferase activity	Molecular function	20061386
RAD54L	8438	RAD54-like (S. cerevisiae)	chromosome organization	Biological process	-
SNX5	27131	sorting nexin 5	phagocytic cup	Cellular component	-
CRIP2	1397	cysteine-rich protein 2	extracellular matrix	Cellular component	20551380
TRAF5	7188	TNF receptor-associated factor 5	ubiquitin-protein transferase activity	Molecular function	-
JAK1	3716	Janus kinase 1	growth hormone receptor binding	Molecular function	10502458
CALM1	801	calmodulin 1 (phosphorylase kinase, delta)	positive regulation of protein dephosphorylation	Biological process	8631777
C2orf50	130813	chromosome 2 open reading frame 50	protein binding	Molecular function	25416956
GATAD2B	57459	GATA zinc finger domain containing 2B	nucleosomal DNA binding	Molecular function	16217013
FBN1	2200	fibrillin 1	heart development	Biological process	15781745
DYNC2LI1	51626	dynein, cytoplasmic 2, light intermediate chain 1	cytoplasmic microtubule	Cellular component	-
CHD2	1106	chromodomain helicase DNA binding protein 2	nucleus	Cellular component	-
TEC	7006	tec protein tyrosine kinase	regulation of cell proliferation	Biological process	-
STAT1	6772	signal transducer and activator of transcription 1, 91kDa	positive regulation of smooth muscle cell proliferation	Biological process	-
PLA2G6	8398	phospholipase A2, group VI (cytosolic, calcium-independent)	cardiolipin acyl-chain remodeling	Biological process	-
SLC17A6	57084	solute carrier family 17 (vesicular glutamate transporter), member 6	neurotransmitter uptake	Biological process	-
RPEL1	729020	ribulose-5-phosphate-3-epimerase-like 1	pentose-phosphate shunt	Biological process	-
POLE2	5427	polymerase (DNA directed), epsilon 2, accessory subunit	mitotic cell cycle	Biological process	-
AXIN2	8313	axin 2	positive regulation of cell death	Biological process	16247484
ATP7A	538	ATPase, Cu++ transporting, alpha polypeptide	copper ion transport	Biological process	11092760
IP6K3	117283	inositol hexakisphosphate kinase 3	inositol-1,4,5-trisphosphate 3-kinase activity	Molecular function	-
FKBP1B	2281	FK506 binding protein 1B, 12.6 kDa	protein peptidyl-prolyl isomerization	Biological process	7513996
ATP1A2	477	ATPase, Na+/K+ transporting, alpha 2 polypeptide	transmembrane transport	Biological process	-
SPIC	121599	Spi-C transcription factor (Spi-1/PU.1 related)	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
RIF1	55183	replication timing regulatory factor 1	plasma membrane	Cellular component	-
NRSN1	140767	neurensin 1	integral component of membrane	Cellular component	-
MARK4	57787	MAP/microtubule affinity-regulating kinase 4	tau-protein kinase activity	Molecular function	14594945
LMTK3	114783	lemur tyrosine kinase 3	protein serine/threonine kinase activity	Molecular function	-
FOLH1B	219595	folate hydrolase 1B	metallopeptidase activity	Molecular function	-
AKR1C1	1645	aldo-keto reductase family 1, member C1	cholesterol homeostasis	Biological process	8486699
MAEL	84944	maelstrom spermatogenic transposon silencer	multicellular organismal development	Biological process	-
SOX9	6662	SRY (sex determining region Y)-box 9	single organismal cell-cell adhesion	Biological process	-
SIRT5	23408	sirtuin 5	protein ADP-ribosylation	Biological process	17456799
IQGAP1	8826	IQ motif containing GTPase activating protein 1	cell junction	Cellular component	-
ARFIP2	23647	ADP-ribosylation factor interacting protein 2	ruffle	Cellular component	8670882
STX4	6810	syntaxin 4	myelin sheath adaxonal region	Cellular component	-
NOXA1	10811	NADPH oxidase activator 1	Rac GTPase binding	Molecular function	16636067
MGP	4256	matrix Gla protein	cell differentiation	Biological process	-
SRPRB	58477	signal recognition particle receptor, B subunit	small GTPase mediated signal transduction	Biological process	-
XCL1	6375	chemokine (C motif) ligand 1	positive regulation of granzyme A production	Biological process	18832695
DAZ3	57054	deleted in azoospermia 3	cell differentiation	Biological process	-
MDK	4192	midkine (neurite growth-promoting factor 2)	positive regulation of cell division	Biological process	-
SFRP5	6425	secreted frizzled-related protein 5	negative regulation of protein kinase B signaling	Biological process	19957335
SUMO2	6613	small ubiquitin-like modifier 2	protein binding	Molecular function	15383276
DPP4	1803	dipeptidyl-peptidase 4	membrane	Cellular component	19946888
SCIMP	388325	SLP adaptor and CSK interacting membrane protein	positive regulation of ERK1 and ERK2 cascade	Biological process	21930792
MTRR	4552	5-methyltetrahydrofolate-homocysteine methyltransferase reductase	[methionine synthase] reductase activity	Molecular function	17892308
MNDA	4332	myeloid cell nuclear differentiation antigen	transcription, DNA-templated	Biological process	-
ME1	4199	malic enzyme 1, NADP(+)-dependent, cytosolic	cellular lipid metabolic process	Biological process	-
SLC23A1	9963	solute carrier family 23 (ascorbic acid transporter), member 1	extracellular exosome	Cellular component	19056867
GCNT3	9245	glucosaminyl (N-acetyl) transferase 3, mucin type	protein O-linked glycosylation	Biological process	-
PCDH11Y	83259	protocadherin 11 Y-linked	integral component of membrane	Cellular component	-
SERTAD2	9792	SERTA domain containing 2	transcription coactivator activity	Molecular function	-
SNW1	22938	SNW domain containing 1	negative regulation of transcription from RNA polymerase II promoter	Biological process	14985122
CEP104	9731	centrosomal protein 104kDa	glycine binding	Molecular function	-
IGFBP5	3488	insulin-like growth factor binding protein 5	osteoblast differentiation	Biological process	-
TMEM41B	440026	transmembrane protein 41B	nervous system development	Biological process	-
ADCK4	79934	aarF domain containing kinase 4	protein serine/threonine kinase activity	Molecular function	-
NT5E	4907	5'-nucleotidase, ecto (CD73)	nucleotide binding	Molecular function	-
HERC1	8925	HECT and RLD domain containing E3 ubiquitin protein ligase family member 1	transport	Biological process	-
PCDHB2	56133	protocadherin beta 2	synapse assembly	Biological process	12231349
NES	10763	nestin	cytoplasm	Cellular component	19384922
SHOX2	6474	short stature homeobox 2	positive regulation of axonogenesis	Biological process	-
HIST1H2BE	8344	histone cluster 1, H2be	DNA binding	Molecular function	422550
APOC3	345	apolipoprotein C-III	triglyceride metabolic process	Biological process	17142127
CRKL	1399	v-crk avian sarcoma virus CT10 oncogene homolog-like	extracellular exosome	Cellular component	23376485
GPR82	27197	G protein-coupled receptor 82	G-protein coupled receptor activity	Molecular function	-
OR5AU1	390445	olfactory receptor, family 5, subfamily AU, member 1	G-protein coupled receptor signaling pathway	Biological process	-
BMP2K	55589	BMP2 inducible kinase	protein phosphorylation	Biological process	-
XXYLT1	152002	xyloside xylosyltransferase 1	endoplasmic reticulum membrane	Cellular component	-
UQCRFS1	7386	ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1	mitochondrial respiratory chain complex III	Cellular component	-
PYGO2	90780	pygopus family PHD finger 2	in utero embryonic development	Biological process	-
TNIP1	10318	TNFAIP3 interacting protein 1	glycoprotein biosynthetic process	Biological process	9923610
OR1J4	26219	olfactory receptor, family 1, subfamily J, member 4	transmembrane signaling receptor activity	Molecular function	-
RPS6KA3	6197	ribosomal protein S6 kinase, 90kDa, polypeptide 3	positive regulation of cell differentiation	Biological process	18813292
HLA-B	3106	major histocompatibility complex, class I, B	integral component of lumenal side of endoplasmic reticulum membrane	Cellular component	-
CLVS1	157807	clavesin 1	trans-Golgi network membrane	Cellular component	-
IFNE	338376	interferon, epsilon	humoral immune response	Biological process	-
NUP35	129401	nucleoporin 35kDa	glucose transport	Biological process	-
VDR	7421	vitamin D (1,25- dihydroxyvitamin D3) receptor	zinc ion binding	Molecular function	-
LINC00470	56651	long intergenic non-protein coding RNA 470	cellular_component	Cellular component	-
GLA	2717	galactosidase, alpha	small molecule metabolic process	Biological process	-
SIRT4	23409	sirtuin 4	protein ADP-ribosylation	Biological process	17456799
SNRNP200	23020	small nuclear ribonucleoprotein 200kDa (U5)	nucleoplasm	Cellular component	-
CDC25C	995	cell division cycle 25C	small GTPase mediated signal transduction	Biological process	-
PKN1	5585	protein kinase N1	nucleoplasm	Cellular component	-
VPS4B	9525	vacuolar protein sorting 4 homolog B (S. cerevisiae)	endosome	Cellular component	11563910
ARHGAP44	9912	Rho GTPase activating protein 44	synapse	Cellular component	-
NLGN4Y	22829	neuroligin 4, Y-linked	learning	Biological process	18628683
OGFOD1	55239	2-oxoglutarate and iron-dependent oxygenase domain containing 1	peptidyl-proline 3-dioxygenase activity	Molecular function	24550462
TYRP1	7306	tyrosinase-related protein 1	endosome membrane	Cellular component	19841138
LOC400943	400943	uncharacterized LOC400943	extracellular region	Cellular component	-
CHMP4C	92421	charged multivesicular body protein 4C	vacuolar transport	Biological process	-
IFT122	55764	intraflagellar transport 122	organelle organization	Biological process	-
SLC23A3	151295	solute carrier family 23, member 3	integral component of membrane	Cellular component	-
CLTCL1	8218	clathrin, heavy chain-like 1	protein binding	Molecular function	19478182
CRYAB	1410	crystallin, alpha B	negative regulation of apoptotic process	Biological process	14752512
KATNAL1	84056	katanin p60 subunit A-like 1	spermatogenesis	Biological process	-
ARHGDIA	396	Rho GDP dissociation inhibitor (GDI) alpha	protein binding	Molecular function	10489445
FAM110C	642273	family with sequence similarity 110, member C	regulation of cell projection assembly	Biological process	19698782
VILL	50853	villin-like	actin binding	Molecular function	-
FGD1	2245	FYVE, RhoGEF and PH domain containing 1	signal transduction	Biological process	8969170
SEMA4D	10507	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	semaphorin-plexin signaling pathway	Biological process	19788569
PIAS1	8554	protein inhibitor of activated STAT, 1	SUMO ligase activity	Molecular function	18579533
GDF2	2658	growth differentiation factor 2	positive regulation of osteoblast differentiation	Biological process	-
GLUL	2752	glutamate-ammonia ligase	glutamate catabolic process	Biological process	21757002
BAZ1A	11177	bromodomain adjacent to zinc finger domain, 1A	protein binding	Molecular function	17500595
EIF4E	1977	eukaryotic translation initiation factor 4E	cytokine-mediated signaling pathway	Biological process	-
ADAM8	101	ADAM metallopeptidase domain 8	leukocyte migration involved in inflammatory response	Biological process	-
PRKCDBP	112464	protein kinase C, delta binding protein	negative regulation of protein kinase B signaling	Biological process	-
ATXN3	4287	ataxin 3	regulation of transcription, DNA-templated	Biological process	-
SPAG7	9552	sperm associated antigen 7	nucleus	Cellular component	-
RGS16	6004	regulator of G-protein signaling 16	visual perception	Biological process	9469939
PERP	64065	PERP, TP53 apoptosis effector	amelogenesis	Biological process	-
DFFA	1676	DNA fragmentation factor, 45kDa, alpha polypeptide	negative regulation of execution phase of apoptosis	Biological process	9564035
GNAS	2778	GNAS complex locus	sensory perception of smell	Biological process	3018580
ZNF45	7596	zinc finger protein 45	sequence-specific DNA binding transcription factor activity	Molecular function	9570955
IFITM3	10410	interferon induced transmembrane protein 3	negative regulation of viral genome replication	Biological process	20943977
WDR75	84128	WD repeat domain 75	nucleolus	Cellular component	-
TGM1	7051	transglutaminase 1	cornified envelope	Cellular component	8824274
IL9R	3581	interleukin 9 receptor	cell proliferation	Biological process	1376929
GLI4	2738	GLI family zinc finger 4	regulation of transcription, DNA-templated	Biological process	-
WT1	7490	Wilms tumor 1	positive regulation of heart growth	Biological process	-
FAM21C	253725	family with sequence similarity 21, member C	retrograde transport, endosome to Golgi	Biological process	19922874
EEF2	1938	eukaryotic translation elongation factor 2	post-translational protein modification	Biological process	-
ERCC1	2067	excision repair cross-complementation group 1	mitotic recombination	Biological process	8811092
FOXC2	2303	forkhead box C2	positive regulation of vascular wound healing	Biological process	-
CACTIN	58509	cactin, spliceosome C complex subunit	negative regulation of tumor necrosis factor production	Biological process	20829348
HEY1	23462	hes-related family bHLH transcription factor with YRPW motif 1	negative regulation of transcription from RNA polymerase II promoter	Biological process	11486045
ELF1	1997	E74-like factor 1 (ets domain transcription factor)	cell differentiation	Biological process	-
MIS18A	54069	MIS18 kinetochore protein A	mitotic nuclear division	Biological process	-
SH3GL2	6456	SH3-domain GRB2-like 2	post-Golgi vesicle-mediated transport	Biological process	-
EPS15	2060	epidermal growth factor receptor pathway substrate 15	ciliary membrane	Cellular component	-
POP4	10775	processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)	protein binding	Molecular function	15096576
PAK7	57144	p21 protein (Cdc42/Rac)-activated kinase 7	regulation of MAPK cascade	Biological process	-
ACOT13	55856	acyl-CoA thioesterase 13	cytosol	Cellular component	-
CORO1A	11151	coronin, actin binding protein, 1A	T cell homeostasis	Biological process	-
UBTD2	92181	ubiquitin domain containing 2	cytoplasm	Cellular component	-
APOA2	336	apolipoprotein A-II	spherical high-density lipoprotein particle	Cellular component	16682745
ARHGEF28	64283	Rho guanine nucleotide exchange factor (GEF) 28	neurofilament cytoskeleton organization	Biological process	-
SDHAF3	57001	succinate dehydrogenase complex assembly factor 3	mitochondrial matrix	Cellular component	-
GDPD5	81544	glycerophosphodiester phosphodiesterase domain containing 5	regulation of timing of cell differentiation	Biological process	-
KIF5C	3800	kinesin family member 5C	microtubule motor activity	Molecular function	9782088
LEFTY2	7044	left-right determination factor 2	regulation of MAPK cascade	Biological process	-
TTI1	9675	TELO2 interacting protein 1	protein binding	Molecular function	20371770
TMPRSS11B	132724	transmembrane protease, serine 11B	serine-type peptidase activity	Molecular function	24498351
CCDC124	115098	coiled-coil domain containing 124	cell cycle	Biological process	-
POTEKP	440915	POTE ankyrin domain family, member K, pseudogene	extracellular exosome	Cellular component	23533145
PCDHA11	56138	protocadherin alpha 11	integral component of plasma membrane	Cellular component	10380929
PXN	5829	paxillin	lamellipodium	Cellular component	12686598
SYK	6850	spleen tyrosine kinase	peptidyl-tyrosine autophosphorylation	Biological process	-
MSH6	2956	mutS homolog 6	reciprocal meiotic recombination	Biological process	-
CXCL12	6387	chemokine (C-X-C motif) ligand 12	chemokine activity	Molecular function	12782716
RAP1GAP	5909	RAP1 GTPase activating protein	regulation of GTPase activity	Biological process	18309292
KCTD14	65987	potassium channel tetramerization domain containing 14	protein binding	Molecular function	25416956
TRPM5	29850	transient receptor potential cation channel, subfamily M, member 5	regulation of ion transmembrane transport	Biological process	-
NOXO1	124056	NADPH oxidase organizer 1	NADPH oxidase complex	Cellular component	16636067
RELA	5970	v-rel avian reticuloendotheliosis viral oncogene homolog A	response to muramyl dipeptide	Biological process	-
GABARAPL2	11345	GABA(A) receptor-associated protein-like 2	ATPase binding	Molecular function	10747018
UFSP2	55325	UFM1-specific peptidase 2	cytoplasm	Cellular component	-
GRHPR	9380	glyoxylate reductase/hydroxypyruvate reductase	glyoxylate reductase (NADP) activity	Molecular function	10524214
TCF3	6929	transcription factor 3	positive regulation of sequence-specific DNA binding transcription factor activity	Biological process	14752053
RHOH	399	ras homolog family member H	immunological synapse	Cellular component	-
PRKACA	5566	protein kinase, cAMP-dependent, catalytic, alpha	regulation of osteoblast differentiation	Biological process	19949837
ALOX12	239	arachidonate 12-lipoxygenase	positive regulation of vasodilation	Biological process	-
STAT5B	6777	signal transducer and activator of transcription 5B	regulation of steroid metabolic process	Biological process	-
RUNX3	864	runt-related transcription factor 3	peripheral nervous system neuron development	Biological process	20096094
ARMC4	55130	armadillo repeat containing 4	cilium movement	Biological process	-
ENOPH1	58478	enolase-phosphatase 1	small molecule metabolic process	Biological process	-
SYNRG	11276	synergin, gamma	endocytosis	Biological process	-
ITGA3	3675	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	neuron migration	Biological process	-
PCNA	5111	proliferating cell nuclear antigen	dinucleotide insertion or deletion binding	Molecular function	11005803
SCRIB	23513	scribbled planar cell polarity protein	cell proliferation	Biological process	16965391
KRT31	3881	keratin 31, type I	epidermis development	Biological process	7578244
ADAMTS9	56999	ADAM metallopeptidase with thrombospondin type 1 motif, 9	metallopeptidase activity	Molecular function	12514189
WASF2	10163	WAS protein family, member 2	small GTPase mediated signal transduction	Biological process	-
RPS27A	6233	ribosomal protein S27a	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	Biological process	-
PHGDH	26227	phosphoglycerate dehydrogenase	extracellular exosome	Cellular component	19056867
HIST1H3G	8355	histone cluster 1, H3g	regulation of gene expression, epigenetic	Biological process	-
KLF5	688	Kruppel-like factor 5 (intestinal)	cellular response to organic cyclic compound	Biological process	-
UQCRC1	7384	ubiquinol-cytochrome c reductase core protein I	response to alkaloid	Biological process	-
OR10A2	341276	olfactory receptor, family 10, subfamily A, member 2	plasma membrane	Cellular component	-
GRIK3	2899	glutamate receptor, ionotropic, kainate 3	terminal bouton	Cellular component	-
BTBD10	84280	BTB (POZ) domain containing 10	type B pancreatic cell proliferation	Biological process	-
PRCP	5547	prolylcarboxypeptidase (angiotensinase C)	plasma membrane	Cellular component	-
ANAPC7	51434	anaphase promoting complex subunit 7	mitotic spindle assembly checkpoint	Biological process	-
BRWD1	54014	bromodomain and WD repeat domain containing 1	transcription, DNA-templated	Biological process	-
NRIP2	83714	nuclear receptor interacting protein 2	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
GIT2	9815	G protein-coupled receptor kinase interacting ArfGAP 2	metal ion binding	Molecular function	-
RAD9A	5883	RAD9 homolog A (S. pombe)	nucleus	Cellular component	12628935
PIK3CD	5293	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	T cell receptor signaling pathway	Biological process	20940048
SUCLA2	8803	succinate-CoA ligase, ADP-forming, beta subunit	mitochondrion	Cellular component	-
GLO1	2739	glyoxalase I	lactoylglutathione lyase activity	Molecular function	11489834
DHRS2	10202	dehydrogenase/reductase (SDR family) member 2	negative regulation of cell proliferation	Biological process	1847869
IL36RN	26525	interleukin 36 receptor antagonist	interleukin-1 receptor binding	Molecular function	-
ABL1	25	ABL proto-oncogene 1, non-receptor tyrosine kinase	substrate adhesion-dependent cell spreading	Biological process	-
CASP6	839	caspase 6, apoptosis-related cysteine peptidase	programmed cell death	Biological process	-
KRT19	3880	keratin 19, type I	cell periphery	Cellular component	19185580
HIST1H4A	8359	histone cluster 1, H4a	histone H4-K20 demethylation	Biological process	-
EGR4	1961	early growth response 4	negative regulation of apoptotic process	Biological process	-
KLF1	10661	Kruppel-like factor 1 (erythroid)	liver development	Biological process	-
HSPB3	8988	heat shock 27kDa protein 3	response to unfolded protein	Biological process	8972725
PRDM14	63978	PR domain containing 14	methyltransferase activity	Molecular function	-
GNAI2	2771	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	nucleoplasm	Cellular component	-
WAS	7454	Wiskott-Aldrich syndrome	actin polymerization or depolymerization	Biological process	8625410
EHHADH	1962	enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase	cytosol	Cellular component	-
SPPL2A	84888	signal peptide peptidase like 2A	plasma membrane	Cellular component	-
HIF1A	3091	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	embryonic placenta development	Biological process	-
APLF	200558	aprataxin and PNKP like factor	single strand break repair	Biological process	17396150
CHST11	50515	carbohydrate (chondroitin 4) sulfotransferase 11	developmental growth	Biological process	-
SYT10	341359	synaptotagmin X	cell junction	Cellular component	-
NUP214	8021	nucleoporin 214kDa	nuclear pore	Cellular component	-
ZNF286A	57335	zinc finger protein 286A	DNA binding	Molecular function	-
NFATC2	4773	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	-
MYCBP	26292	MYC binding protein	spermatogenesis	Biological process	12151104
SMG5	23381	SMG5 nonsense mediated mRNA decay factor	protein binding	Molecular function	12699629
BSX	390259	brain-specific homeobox	sequence-specific DNA binding	Molecular function	-
ARL6IP5	10550	ADP-ribosylation factor-like 6 interacting protein 5	intrinsic apoptotic signaling pathway in response to oxidative stress	Biological process	18387645
CBR4	84869	carbonyl reductase 4	oxidation-reduction process	Biological process	-
KRT8	3856	keratin 8, type II	Z disc	Cellular component	-
PDE6H	5149	phosphodiesterase 6H, cGMP-specific, cone, gamma	metabolic process	Biological process	-
TOMM34	10953	translocase of outer mitochondrial membrane 34	heat shock protein binding	Molecular function	9660753
SPINK4	27290	serine peptidase inhibitor, Kazal type 4	response to drug	Biological process	-
SP140	11262	SP140 nuclear body protein	protein binding	Molecular function	24267382
EDF1	8721	endothelial differentiation-related factor 1	multicellular organismal development	Biological process	-
PKMYT1	9088	protein kinase, membrane associated tyrosine/threonine 1	protein kinase activity	Molecular function	9001210
ENG	2022	endoglin	positive regulation of protein phosphorylation	Biological process	12015308
NEUROD4	58158	neuronal differentiation 4	neuroblast proliferation	Biological process	-
CNP	1267	2',3'-cyclic nucleotide 3' phosphodiesterase	aging	Biological process	-
SOX5	6660	SRY (sex determining region Y)-box 5	negative regulation of transcription, DNA-templated	Biological process	-
SAP30	8819	Sin3A-associated protein, 30kDa	negative regulation of gene expression, epigenetic	Biological process	-
FMN2	56776	formin 2	polar body extrusion after meiotic divisions	Biological process	-
PDCL3	79031	phosducin-like 3	angiogenesis	Biological process	-
MRPL30	51263	mitochondrial ribosomal protein L30	ribosome	Cellular component	-
SNCG	6623	synuclein, gamma (breast cancer-specific protein 1)	response to drug	Biological process	-
HECTD4	283450	HECT domain containing E3 ubiquitin protein ligase 4	glucose metabolic process	Biological process	23575436
PTH1R	5745	parathyroid hormone 1 receptor	cytoplasm	Cellular component	10709993
UQCRC1	7384	ubiquinol-cytochrome c reductase core protein I	ubiquitin protein ligase binding	Molecular function	19725078
PCID2	55795	PCI domain containing 2	positive regulation of B cell differentiation	Biological process	-
RABGAP1	23637	RAB GTPase activating protein 1	positive regulation of GTPase activity	Biological process	10202141
ALOX12	239	arachidonate 12-lipoxygenase	positive regulation of endothelial cell migration	Biological process	-
AHCYL1	10768	adenosylhomocysteinase-like 1	protein export from nucleus	Biological process	-
GINS4	84296	GINS complex subunit 4 (Sld5 homolog)	DNA strand elongation involved in DNA replication	Biological process	-
MYADM	91663	myeloid-associated differentiation marker	cell-cell junction	Cellular component	23264465
DMRT2	10655	doublesex and mab-3 related transcription factor 2	metal ion binding	Molecular function	-
CEP70	80321	centrosomal protein 70kDa	cytoplasm	Cellular component	-
CCNE2	9134	cyclin E2	mitotic cell cycle	Biological process	-
CCNA2	890	cyclin A2	positive regulation of transcription, DNA-templated	Biological process	-
OR10P1	121130	olfactory receptor, family 10, subfamily P, member 1	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
SMARCA5	8467	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	protein binding	Molecular function	10662543
SIRT1	23411	sirtuin 1	regulation of cell proliferation	Biological process	12006491
B3GNT7	93010	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7	glycosaminoglycan metabolic process	Biological process	-
CDH10	1008	cadherin 10, type 2 (T2-cadherin)	adherens junction organization	Biological process	-
MIXL1	83881	Mix paired-like homeobox	heart development	Biological process	-
UMODL1	89766	uromodulin-like 1	adipose tissue development	Biological process	-
INHBB	3625	inhibin, beta B	negative regulation of insulin secretion	Biological process	-
HINT2	84681	histidine triad nucleotide binding protein 2	steroid biosynthetic process	Biological process	-
ARPP21	10777	cAMP-regulated phosphoprotein, 21kDa	biological_process	Biological process	-
RABGAP1L	9910	RAB GTPase activating protein 1-like	early endosome	Cellular component	16923123
TRPC3	7222	transient receptor potential cation channel, subfamily C, member 3	phototransduction	Biological process	9215637
TMEM165	55858	transmembrane protein 165	Golgi apparatus	Cellular component	-
MIA	8190	melanoma inhibitory activity	extracellular space	Cellular component	7923218
TNFSF12	8742	tumor necrosis factor (ligand) superfamily, member 12	endothelial cell migration	Biological process	14961121
GRM5	2915	glutamate receptor, metabotropic 5	dendritic shaft	Cellular component	-
KRTAP10-10	353333	keratin associated protein 10-10	keratin filament	Cellular component	-
CDH1	999	cadherin 1, type 1, E-cadherin (epithelial)	regulation of protein localization to cell surface	Biological process	-
ZWILCH	55055	zwilch kinetochore protein	mitotic nuclear division	Biological process	-
NLRC5	84166	NLR family, CARD domain containing 5	innate immune response	Biological process	-
NRXN1	9378	neurexin 1	angiogenesis	Biological process	-
SUPT16H	11198	suppressor of Ty 16 homolog (S. cerevisiae)	protein binding	Molecular function	16902406
PPP1R35	221908	protein phosphatase 1, regulatory subunit 35	phosphatase binding	Molecular function	19389623
ITGB1	3688	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	dendritic spine	Cellular component	-
CEND1	51286	cell cycle exit and neuronal differentiation 1	adult walking behavior	Biological process	-
CASP3	836	caspase 3, apoptosis-related cysteine peptidase	T cell homeostasis	Biological process	-
PRKCB	5579	protein kinase C, beta	cellular calcium ion homeostasis	Biological process	-
TRIAP1	51499	TP53 regulated inhibitor of apoptosis 1	p53 binding	Molecular function	15735003
DDR2	4921	discoidin domain receptor tyrosine kinase 2	plasma membrane	Cellular component	-
POU4F2	5458	POU class 4 homeobox 2	axon extension	Biological process	-
MXD4	10608	MAX dimerization protein 4	protein dimerization activity	Molecular function	-
RHBDD1	84236	rhomboid domain containing 1	serine-type endopeptidase activity	Molecular function	-
PDSS2	57107	prenyl (decaprenyl) diphosphate synthase, subunit 2	small molecule metabolic process	Biological process	-
TNNC1	7134	troponin C type 1 (slow)	protein homodimerization activity	Molecular function	18092822
HBZ	3050	hemoglobin, zeta	heme binding	Molecular function	-
RDH10	157506	retinol dehydrogenase 10 (all-trans)	integral component of membrane	Cellular component	19458327
CDO1	1036	cysteine dioxygenase type 1	sulfur amino acid biosynthetic process	Biological process	12110289
SSB	6741	Sjogren syndrome antigen B (autoantigen La)	histone mRNA metabolic process	Biological process	9154801
CLTB	1212	clathrin, light chain B	clathrin-mediated endocytosis	Biological process	-
MTSS1	9788	metastasis suppressor 1	transmembrane receptor protein tyrosine kinase signaling pathway	Biological process	12570871
ANTXR1	84168	anthrax toxin receptor 1	plasma membrane	Cellular component	-
RAD51	5888	RAD51 recombinase	cellular response to ionizing radiation	Biological process	23509288
EGR1	1958	early growth response 1	double-stranded DNA binding	Molecular function	-
ARL5C	390790	ADP-ribosylation factor-like 5C	small GTPase mediated signal transduction	Biological process	-
CAPRIN2	65981	caprin family member 2	nucleus	Cellular component	-
ACVR1B	91	activin A receptor, type IB	signal transduction by protein phosphorylation	Biological process	-
ADAMTSL1	92949	ADAMTS-like 1	post-translational protein modification	Biological process	-
SEMA4F	10505	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F	negative regulation of axon extension	Biological process	-
BDNF	627	brain-derived neurotrophic factor	negative regulation of neuroblast proliferation	Biological process	-
SP3	6670	Sp3 transcription factor	Golgi apparatus	Cellular component	-
KRTAP21-2	337978	keratin associated protein 21-2	structural constituent of cutaneous appendage	Molecular function	-
GATA6	2627	GATA binding protein 6	negative regulation of apoptotic process	Biological process	21127043
CXCL17	284340	chemokine (C-X-C motif) ligand 17	angiogenesis	Biological process	-
ATXN1	6310	ataxin 1	transcription, DNA-templated	Biological process	-
RPS6KA4	8986	ribosomal protein S6 kinase, 90kDa, polypeptide 4	histone phosphorylation	Biological process	20018936
RFX2	5990	regulatory factor X, 2 (influences HLA class II expression)	regulation of transcription from RNA polymerase II promoter	Biological process	-
LPPR5	163404	lipid phosphate phosphatase-related protein type 5	hydrolase activity	Molecular function	-
DPM1	8813	dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit	protein mannosylation	Biological process	9535917
FSHB	2488	follicle stimulating hormone, beta polypeptide	signal transduction	Biological process	8220432
MYO1B	4430	myosin IB	early endosome	Cellular component	16219689
SPG21	51324	spastic paraplegia 21 (autosomal recessive, Mast syndrome)	cytosol	Cellular component	11113139
ACO1	48	aconitase 1, soluble	iron-responsive element binding	Molecular function	8041788
GTF2H1	2965	general transcription factor IIH, polypeptide 1, 62kDa	termination of RNA polymerase I transcription	Biological process	-
CRYGA	1418	crystallin, gamma A	structural constituent of eye lens	Molecular function	12507494
DPP10	57628	dipeptidyl-peptidase 10 (non-functional)	protein localization to plasma membrane	Biological process	-
QKI	9444	QKI, KH domain containing, RNA binding	protein binding	Molecular function	16189514
GPR12	2835	G protein-coupled receptor 12	cellular calcium ion homeostasis	Biological process	-
MCM2	4171	minichromosome maintenance complex component 2	mitotic cell cycle	Biological process	-
COMT	1312	catechol-O-methyltransferase	integral component of membrane	Cellular component	-
RALGDS	5900	ral guanine nucleotide dissociation stimulator	positive regulation of GTPase activity	Biological process	-
TOB1	10140	transducer of ERBB2, 1	SMAD protein import into nucleus	Biological process	-
NDFIP2	54602	Nedd4 family interacting protein 2	perinuclear region of cytoplasm	Cellular component	18776082
CTSV	1515	cathepsin V	aminopeptidase activity	Molecular function	-
CNOT1	23019	CCR4-NOT transcription complex, subunit 1	peroxisomal membrane	Cellular component	21525035
TRAF6	7189	TNF receptor-associated factor 6, E3 ubiquitin protein ligase	cell development	Biological process	-
MAP3K1	4214	mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase	toll-like receptor TLR6:TLR2 signaling pathway	Biological process	-
HNF1B	6928	HNF1 homeobox B	inner cell mass cell differentiation	Biological process	-
AGO2	27161	argonaute RISC catalytic component 2	siRNA loading onto RISC involved in RNA interference	Biological process	19966796
KCNA5	3741	potassium channel, voltage gated shaker related subfamily A, member 5	potassium ion transmembrane transport	Biological process	12130714
BNIP3	664	BCL2/adenovirus E1B 19kDa interacting protein 3	nuclear envelope	Cellular component	7954800
IRF7	3665	interferon regulatory factor 7	regulation of adaptive immune response	Biological process	17404045
STAU1	6780	staufen double-stranded RNA binding protein 1	neuronal cell body	Cellular component	-
LIX1L	128077	Lix1 homolog (chicken) like	cellular_component	Cellular component	-
RACGAP1	29127	Rac GTPase activating protein 1	positive regulation of cytokinesis	Biological process	11782313
GRIA4	2893	glutamate receptor, ionotropic, AMPA 4	extracellular-glutamate-gated ion channel activity	Molecular function	-
SOX2	6657	SRY (sex determining region Y)-box 2	negative regulation of neuron differentiation	Biological process	-
B4GALT4	8702	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4	carbohydrate metabolic process	Biological process	-
NR1I2	8856	nuclear receptor subfamily 1, group I, member 2	transcription coactivator activity	Molecular function	9727070
KLHL21	9903	kelch-like family member 21	chromosome passenger complex localization to spindle midzone	Biological process	19995937
TAF9B	51616	TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa	transcription corepressor activity	Molecular function	12837753
KCNQ4	9132	potassium channel, voltage gated KQT-like subfamily Q, member 4	basal plasma membrane	Cellular component	-
NOD2	64127	nucleotide-binding oligomerization domain containing 2	positive regulation of ERK1 and ERK2 cascade	Biological process	-
SLC39A4	55630	solute carrier family 39 (zinc transporter), member 4	zinc II ion transmembrane transport	Biological process	-
GABBR2	9568	gamma-aminobutyric acid (GABA) B receptor, 2	postsynaptic membrane	Cellular component	-
DMP1	1758	dentin matrix acidic phosphoprotein 1	biomineral tissue development	Biological process	-
PIAS4	51588	protein inhibitor of activated STAT, 4	transcription, DNA-templated	Biological process	-
PPARG	5468	peroxisome proliferator-activated receptor gamma	response to metformin	Biological process	-
OR7G1	125962	olfactory receptor, family 7, subfamily G, member 1	olfactory receptor activity	Molecular function	-
NLRP4	147945	NLR family, pyrin domain containing 4	ATP binding	Molecular function	-
SLC16A7	9194	solute carrier family 16 (monocarboxylate transporter), member 7	lactate transmembrane transport	Biological process	9786900
SULF1	23213	sulfatase 1	heparan sulfate proteoglycan metabolic process	Biological process	12368295
MASP1	5648	mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)	protein homodimerization activity	Molecular function	18596036
OAZ3	51686	ornithine decarboxylase antizyme 3	positive regulation of protein catabolic process	Biological process	-
TNP1	7141	transition protein 1 (during histone to protamine replacement)	sexual reproduction	Biological process	10781074
CAMK2D	817	calcium/calmodulin-dependent protein kinase II delta	titin binding	Molecular function	23283722
FGD1	2245	FYVE, RhoGEF and PH domain containing 1	organ morphogenesis	Biological process	7954831
PRKAG1	5571	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	cAMP-dependent protein kinase activity	Molecular function	9598317
UNCX	340260	UNC homeobox	sequence-specific DNA binding	Molecular function	-
PARG	8505	poly (ADP-ribose) glycohydrolase	intracellular membrane-bounded organelle	Cellular component	-
DCTN2	10540	dynactin 2 (p50)	mitotic cell cycle	Biological process	-
SCFD1	23256	sec1 family domain containing 1	negative regulation of autophagosome assembly	Biological process	21242315
PDGFA	5154	platelet-derived growth factor alpha polypeptide	actin cytoskeleton organization	Biological process	-
NIPBL	25836	Nipped-B homolog (Drosophila)	fat cell differentiation	Biological process	-
RASGRP1	10125	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	mast cell degranulation	Biological process	-
GOLT1B	51026	golgi transport 1B	lipid metabolic process	Biological process	-
PNP	4860	purine nucleoside phosphorylase	purine-nucleoside phosphorylase activity	Molecular function	16930574
THRAP3	9967	thyroid hormone receptor associated protein 3	exon-exon junction complex	Cellular component	20123736
ARAP2	116984	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2	GTPase activator activity	Molecular function	-
COG7	91949	component of oligomeric golgi complex 7	intracellular protein transport	Biological process	15107842
ADAMTS7	11173	ADAM metallopeptidase with thrombospondin type 1 motif, 7	proteolysis involved in cellular protein catabolic process	Biological process	18485748
LIPI	149998	lipase, member I	phospholipase activity	Molecular function	12963729
LDHAL6A	160287	lactate dehydrogenase A-like 6A	L-lactate dehydrogenase activity	Molecular function	-
CUX2	23316	cut-like homeobox 2	sequence-specific DNA binding	Molecular function	15656993
INO80	54617	INO80 complex subunit	cellular response to UV	Biological process	18026119
VPS37D	155382	vacuolar protein sorting 37 homolog D (S. cerevisiae)	endosome membrane	Cellular component	-
PML	5371	promyelocytic leukemia	protein homodimerization activity	Molecular function	9230084
ALB	213	albumin	basement membrane	Cellular component	-
GHSR	2693	growth hormone secretagogue receptor	negative regulation of interleukin-6 biosynthetic process	Biological process	15232612
ARG1	383	arginase 1	positive regulation of endothelial cell proliferation	Biological process	-
PARP1	142	poly (ADP-ribose) polymerase 1	NAD+ ADP-ribosyltransferase activity	Molecular function	-
C9orf69	90120	chromosome 9 open reading frame 69	cell cycle	Biological process	-
RNF207	388591	ring finger protein 207	cell-cell signaling involved in cardiac conduction	Biological process	-
VCL	7414	vinculin	epithelial cell-cell adhesion	Biological process	20086044
CDK4	1019	cyclin-dependent kinase 4	regulation of gene expression	Biological process	17420273
PTEN	5728	phosphatase and tensin homolog	multicellular organismal response to stress	Biological process	-
ONECUT3	390874	one cut homeobox 3	cell differentiation	Biological process	-
PGAM2	5224	phosphoglycerate mutase 2 (muscle)	response to mercury ion	Biological process	-
ARHGEF1	9138	Rho guanine nucleotide exchange factor (GEF) 1	protein binding	Molecular function	12681510
ARHGAP11B	89839	Rho GTPase activating protein 11B	cytosol	Cellular component	-
PPP1CC	5501	protein phosphatase 1, catalytic subunit, gamma isozyme	neuron differentiation	Biological process	-
HTR2B	3357	5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled	protein kinase C-activating G-protein coupled receptor signaling pathway	Biological process	-
CCT6B	10693	chaperonin containing TCP1, subunit 6B (zeta 2)	protein transporter activity	Molecular function	8812458
HORMAD1	84072	HORMA domain containing 1	regulation of homologous chromosome segregation	Biological process	-
WIPF1	7456	WAS/WASL interacting protein family, member 1	cytoplasmic membrane-bounded vesicle	Cellular component	-
SFRP1	6422	secreted frizzled-related protein 1	positive regulation of apoptotic process	Biological process	16149051
RELB	5971	v-rel avian reticuloendotheliosis viral oncogene homolog B	core promoter binding	Molecular function	-
PGAM4	441531	phosphoglycerate mutase family member 4	bisphosphoglycerate mutase activity	Molecular function	-
CRKL	1399	v-crk avian sarcoma virus CT10 oncogene homolog-like	SH3/SH2 adaptor activity	Molecular function	8798523
DYNC1H1	1778	dynein, cytoplasmic 1, heavy chain 1	stress granule assembly	Biological process	-
ATP6V1C1	528	ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1	transferrin transport	Biological process	-
PANK3	79646	pantothenate kinase 3	pantothenate kinase activity	Molecular function	-
LAIR2	3904	leukocyte-associated immunoglobulin-like receptor 2	protein binding	Molecular function	25416956
IFI16	3428	interferon, gamma-inducible protein 16	inflammatory response	Biological process	-
AMOTL2	51421	angiomotin like 2	Wnt signaling pathway	Biological process	-
KDM4C	23081	lysine (K)-specific demethylase 4C	dioxygenase activity	Molecular function	-
MATN1	4146	matrilin 1, cartilage matrix protein	proteinaceous extracellular matrix	Cellular component	-
EGLN3	112399	egl-9 family hypoxia-inducible factor 3	cellular response to DNA damage stimulus	Biological process	-
ANAPC4	29945	anaphase promoting complex subunit 4	protein phosphatase binding	Molecular function	21241890
BBC3	27113	BCL2 binding component 3	programmed cell death	Biological process	-
DPP3	10072	dipeptidyl-peptidase 3	extracellular exosome	Cellular component	20458337
SAMD9L	219285	sterile alpha motif domain containing 9-like	early endosome	Cellular component	-
MATR3	9782	matrin 3	posttranscriptional regulation of gene expression	Biological process	21771347
PCDH11X	27328	protocadherin 11 X-linked	plasma membrane	Cellular component	10644456
HIP1R	9026	huntingtin interacting protein 1 related	clathrin-coated vesicle membrane	Cellular component	-
OCRL	4952	oculocerebrorenal syndrome of Lowe	GTPase activator activity	Molecular function	12915445
SSTR3	6753	somatostatin receptor 3	protein binding	Molecular function	19071123
SOX9	6662	SRY (sex determining region Y)-box 9	ERK1 and ERK2 cascade	Biological process	21512138
IL1A	3552	interleukin 1, alpha	extrinsic apoptotic signaling pathway in absence of ligand	Biological process	-
SUDS3	64426	suppressor of defective silencing 3 homolog (S. cerevisiae)	Sin3 complex	Cellular component	11909966
CCNH	902	cyclin H	termination of RNA polymerase I transcription	Biological process	-
NFS1	9054	NFS1 cysteine desulfurase	iron-sulfur cluster binding	Molecular function	-
MRPS11	64963	mitochondrial ribosomal protein S11	mitochondrial inner membrane	Cellular component	-
CALM1	801	calmodulin 1 (phosphorylase kinase, delta)	sarcomere	Cellular component	20226167
TGFB1	7040	transforming growth factor, beta 1	SMAD protein signal transduction	Biological process	-
GRK6	2870	G protein-coupled receptor kinase 6	Wnt signaling pathway	Biological process	-
PDE5A	8654	phosphodiesterase 5A, cGMP-specific	regulation of cGMP metabolic process	Biological process	-
NFKB1	4790	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	chromatin binding	Molecular function	-
WNT6	7475	wingless-type MMTV integration site family, member 6	axis specification	Biological process	-
TUBGCP2	10844	tubulin, gamma complex associated protein 2	spindle pole	Cellular component	-
TARDBP	23435	TAR DNA binding protein	sequence-specific DNA binding transcription factor activity	Molecular function	7745706
TUBG1	7283	tubulin, gamma 1	polar microtubule	Cellular component	9566969
BICD1	636	bicaudal D homolog 1 (Drosophila)	negative regulation of phospholipase C activity	Biological process	-
YME1L1	10730	YME1-like 1 ATPase	cell proliferation	Biological process	22262461
KLF7	8609	Kruppel-like factor 7 (ubiquitous)	DNA binding	Molecular function	-
THNSL1	79896	threonine synthase-like 1 (S. cerevisiae)	mitochondrion	Cellular component	-
CREB3L2	64764	cAMP responsive element binding protein 3-like 2	response to endoplasmic reticulum stress	Biological process	17178827
LPAR3	23566	lysophosphatidic acid receptor 3	bleb assembly	Biological process	-
DNMBP	23268	dynamin binding protein	synapse	Cellular component	-
BMP7	655	bone morphogenetic protein 7	axon guidance	Biological process	-
COG6	57511	component of oligomeric golgi complex 6	Golgi membrane	Cellular component	-
RAC1	5879	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	cytoplasmic ribonucleoprotein granule	Cellular component	15121898
RUNX1	861	runt-related transcription factor 1	positive regulation of angiogenesis	Biological process	-
FOXD1	2297	forkhead box D1	metanephric capsule development	Biological process	-
FAM132A	388581	family with sequence similarity 132, member A	regulation of glucose import	Biological process	-
CHRNB2	1141	cholinergic receptor, nicotinic, beta 2 (neuronal)	ion transmembrane transport	Biological process	20438829
MSH3	4437	mutS homolog 3	single-stranded DNA binding	Molecular function	11809883
RCSD1	92241	RCSD domain containing 1	actin filament	Cellular component	15850461
CORO1C	23603	coronin, actin binding protein, 1C	actin cytoskeleton	Cellular component	22364218
FGF16	8823	fibroblast growth factor 16	regulation of endothelial cell proliferation	Biological process	16756958
KDM4C	23081	lysine (K)-specific demethylase 4C	oxidation-reduction process	Biological process	-
HTR2B	3357	5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled	embryonic morphogenesis	Biological process	-
DAGLB	221955	diacylglycerol lipase, beta	lipase activity	Molecular function	-
COL7A1	1294	collagen, type VII, alpha 1	identical protein binding	Molecular function	-
SRSF3	6428	serine/arginine-rich splicing factor 3	nucleotide binding	Molecular function	-
DCLRE1B	64858	DNA cross-link repair 1B	centrosome	Cellular component	19197158
SRF	6722	serum response factor (c-fos serum response element-binding transcription factor)	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	-
PRMT6	55170	protein arginine methyltransferase 6	base-excision repair	Biological process	16600869
IGFBP3	3486	insulin-like growth factor binding protein 3	insulin-like growth factor I binding	Molecular function	10766744
PARK2	5071	parkin RBR E3 ubiquitin protein ligase	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway	Biological process	17314283
JUN	3725	jun proto-oncogene	negative regulation by host of viral transcription	Biological process	2833704
NCL	4691	nucleolin	nucleoplasm	Cellular component	23353999
OPN1LW	5956	opsin 1 (cone pigments), long-wave-sensitive	visual perception	Biological process	-
CHIA	27159	chitinase, acidic	chitin binding	Molecular function	11085997
TRAF4	9618	TNF receptor-associated factor 4	positive regulation of protein kinase activity	Biological process	16157600
PKD1	5310	polycystic kidney disease 1 (autosomal dominant)	calcium-independent cell-matrix adhesion	Biological process	10861291
RPL39	6170	ribosomal protein L39	cytosolic large ribosomal subunit	Cellular component	8764829
PITPNA	5306	phosphatidylinositol transfer protein, alpha	cytoplasm	Cellular component	-
MAP3K1	4214	mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase	activation of MAPKK activity	Biological process	9808624
PPY	5539	pancreatic polypeptide	cell	Cellular component	2997153
WWC2	80014	WW and C2 domain containing 2	cytosol	Cellular component	24682284
EDF1	8721	endothelial differentiation-related factor 1	sequence-specific DNA binding transcription factor activity	Molecular function	12040021
HSPB11	51668	heat shock protein family B (small), member 11	smoothened signaling pathway	Biological process	-
RAPGEF2	9693	Rap guanine nucleotide exchange factor (GEF) 2	protein binding	Molecular function	10548487
PABPC1	26986	poly(A) binding protein, cytoplasmic 1	nucleus	Cellular component	21940797
TFAP2B	7021	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	fat cell differentiation	Biological process	16373396
PTK6	5753	protein tyrosine kinase 6	cytoplasm	Cellular component	15572663
ASRGL1	80150	asparaginase like 1	asparagine catabolic process via L-aspartate	Biological process	-
LMLN	89782	leishmanolysin-like (metallopeptidase M8 family)	cell adhesion	Biological process	-
ENPP2	5168	ectonucleotide pyrophosphatase/phosphodiesterase 2	phospholipid catabolic process	Biological process	15280042
CSF3	1440	colony stimulating factor 3 (granulocyte)	positive regulation of transcription from RNA polymerase II promoter	Biological process	23001182
C3	718	complement component 3	regulation of triglyceride biosynthetic process	Biological process	10432298
NOD2	64127	nucleotide-binding oligomerization domain containing 2	CARD domain binding	Molecular function	11087742
EDEM1	9695	ER degradation enhancer, mannosidase alpha-like 1	endoplasmic reticulum unfolded protein response	Biological process	-
PCDHGA12	26025	protocadherin gamma subfamily A, 12	calcium ion binding	Molecular function	-
TYROBP	7305	TYRO protein tyrosine kinase binding protein	intracellular	Cellular component	9490415
PMS1	5378	PMS1 postmeiotic segregation increased 1 (S. cerevisiae)	nucleus	Cellular component	8072530
BNIP3	664	BCL2/adenovirus E1B 19kDa interacting protein 3	cellular response to hydrogen peroxide	Biological process	-
POLDIP2	26073	polymerase (DNA-directed), delta interacting protein 2	nucleus	Cellular component	-
APC	324	adenomatous polyposis coli	ruffle membrane	Cellular component	19151759
BMPR2	659	bone morphogenetic protein receptor, type II (serine/threonine kinase)	integral component of plasma membrane	Cellular component	12045205
LAMP1	3916	lysosomal-associated membrane protein 1	positive regulation of natural killer cell mediated cytotoxicity	Biological process	23632890
POC1A	25886	POC1 centriolar protein A	centriole	Cellular component	20008567
KCNH6	81033	potassium channel, voltage gated eag related subfamily H, member 6	potassium ion transmembrane transport	Biological process	-
TIMM22	29928	translocase of inner mitochondrial membrane 22 homolog (yeast)	protein import into mitochondrial inner membrane	Biological process	14726512
HIST2H2BF	440689	histone cluster 2, H2bf	molecular_function	Molecular function	-
SUGT1	10910	SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)	cytosol	Cellular component	-
ISLR2	57611	immunoglobulin superfamily containing leucine-rich repeat 2	integral component of membrane	Cellular component	-
MT1F	4494	metallothionein 1F	cytoplasm	Cellular component	8619255
PICK1	9463	protein interacting with PRKCA 1	protein binding	Molecular function	11802773
GABRR2	2570	gamma-aminobutyric acid (GABA) A receptor, rho 2	plasma membrane	Cellular component	-
NUP160	23279	nucleoporin 160kDa	mitotic nuclear envelope disassembly	Biological process	-
RAD54L	8438	RAD54-like (S. cerevisiae)	DNA recombination	Biological process	8805304
TOP2A	7153	topoisomerase (DNA) II alpha 170kDa	apoptotic chromosome condensation	Biological process	10959840
UBE2D3	7323	ubiquitin-conjugating enzyme E2D 3	MyD88-independent toll-like receptor signaling pathway	Biological process	-
ZNF777	27153	zinc finger protein 777	biological_process	Biological process	-
TLR4	7099	toll-like receptor 4	receptor activity	Molecular function	10426995
CLN6	54982	ceroid-lipofuscinosis, neuronal 6, late infantile, variant	lysosomal lumen acidification	Biological process	11722572
CALR	811	calreticulin	androgen receptor binding	Molecular function	8107809
GRIP1	23426	glutamate receptor interacting protein 1	cytosol	Cellular component	-
P2RY1	5028	purinergic receptor P2Y, G-protein coupled, 1	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway	Biological process	-
TAL1	6886	T-cell acute lymphocytic leukemia 1	chromatin binding	Molecular function	16763211
SYNE1	23345	spectrin repeat containing, nuclear envelope 1	nuclear outer membrane	Cellular component	-
TNFRSF14	8764	tumor necrosis factor receptor superfamily, member 14	cell surface receptor signaling pathway	Biological process	9153189
SLC35E3	55508	solute carrier family 35, member E3	carbohydrate derivative transport	Biological process	-
MT3	4504	metallothionein 3	positive regulation of cell death	Biological process	-
PCCB	5096	propionyl CoA carboxylase, beta polypeptide	short-chain fatty acid catabolic process	Biological process	-
EGLN2	112398	egl-9 family hypoxia-inducible factor 2	regulation of cell growth	Biological process	11850811
SNAI2	6591	snail family zinc finger 2	pigmentation	Biological process	12444107
CD3E	916	CD3e molecule, epsilon (CD3-TCR complex)	immunological synapse	Cellular component	-
ATR	545	ATR serine/threonine kinase	protein dimerization activity	Molecular function	-
PPP1CB	5500	protein phosphatase 1, catalytic subunit, beta isozyme	regulation of glycogen biosynthetic process	Biological process	-
PTGES3	10728	prostaglandin E synthase 3 (cytosolic)	cyclooxygenase pathway	Biological process	-
ZNF33B	7582	zinc finger protein 33B	sequence-specific DNA binding transcription factor activity	Molecular function	-
ABLIM1	3983	actin binding LIM protein 1	lamellipodium	Cellular component	22684256
FBP2	8789	fructose-1,6-bisphosphatase 2	carbohydrate metabolic process	Biological process	-
ZBTB26	57684	zinc finger and BTB domain containing 26	protein binding	Molecular function	25416956
SCGB2A2	4250	secretoglobin, family 2A, member 2	molecular_function	Molecular function	-
AGT	183	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	smooth muscle cell differentiation	Biological process	-
ACKR2	1238	atypical chemokine receptor 2	C-X-C chemokine receptor activity	Molecular function	-
ZC3H11A	9877	zinc finger CCCH-type containing 11A	protein binding	Molecular function	16189514
ERCC3	2071	excision repair cross-complementation group 3	positive regulation of apoptotic process	Biological process	16914395
MB21D1	115004	Mab-21 domain containing 1	metal ion binding	Molecular function	-
TOP2A	7153	topoisomerase (DNA) II alpha 170kDa	DNA topoisomerase complex (ATP-hydrolyzing)	Cellular component	10473615
HFE	3077	hemochromatosis	immune system process	Biological process	8696333
CHST10	9486	carbohydrate sulfotransferase 10	cell adhesion	Biological process	9478973
LEPROT	54741	leptin receptor overlapping transcript	negative regulation of JAK-STAT cascade	Biological process	18042720
ESR1	2099	estrogen receptor 1	positive regulation of nitric oxide biosynthetic process	Biological process	21937726
PTPRR	5801	protein tyrosine phosphatase, receptor type, R	perinuclear region of cytoplasm	Cellular component	-
RNMT	8731	RNA (guanine-7-) methyltransferase	protein binding	Molecular function	22099306
EMC3	55831	ER membrane protein complex subunit 3	biological_process	Biological process	-
CTSC	1075	cathepsin C	activation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	-
MOCS3	27304	molybdenum cofactor synthesis 3	metal ion binding	Molecular function	-
HMGA1	3159	high mobility group AT-hook 1	senescence-associated heterochromatin focus	Cellular component	16901784
UGT1A1	54658	UDP glucuronosyltransferase 1 family, polypeptide A1	negative regulation of steroid metabolic process	Biological process	19996319
CUL4B	8450	cullin 4B	Cul4B-RING E3 ubiquitin ligase complex	Cellular component	18794347
PLXNB1	5364	plexin B1	transmembrane signaling receptor activity	Molecular function	10520995
CASQ1	844	calsequestrin 1 (fast-twitch, skeletal muscle)	response to heat	Biological process	-
DDX58	23586	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	ATP binding	Molecular function	-
BMP2	650	bone morphogenetic protein 2	positive regulation of epithelial to mesenchymal transition	Biological process	20890042
ADPRHL1	113622	ADP-ribosylhydrolase like 1	magnesium ion binding	Molecular function	-
NGF	4803	nerve growth factor (beta polypeptide)	endosome	Cellular component	-
CASP8	841	caspase 8, apoptosis-related cysteine peptidase	regulation of necrotic cell death	Biological process	-
TBX5	6910	T-box 5	negative regulation of epithelial to mesenchymal transition	Biological process	20299672
TCF15	6939	transcription factor 15 (basic helix-loop-helix)	transcription, DNA-templated	Biological process	-
PTGDS	5730	prostaglandin D2 synthase 21kDa (brain)	transport	Biological process	-
ALDH3A2	224	aldehyde dehydrogenase 3 family, member A2	aldehyde dehydrogenase (NAD) activity	Molecular function	15110319
ENPP6	133121	ectonucleotide pyrophosphatase/phosphodiesterase 6	extracellular exosome	Cellular component	19056867
NAALADL1	10004	N-acetylated alpha-linked acidic dipeptidase-like 1	dipeptidase activity	Molecular function	-
KCNK18	338567	potassium channel, two pore domain subfamily K, member 18	calcium-activated potassium channel activity	Molecular function	-
NCLN	56926	nicalin	protein destabilization	Biological process	20538592
CAMK2D	817	calcium/calmodulin-dependent protein kinase II delta	perinuclear region of cytoplasm	Cellular component	-
BOP1	23246	block of proliferation 1	protein binding	Molecular function	16043514
SMARCA4	6597	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	aortic smooth muscle cell differentiation	Biological process	-
ENPP5	59084	ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)	extracellular region	Cellular component	-
RBM3	5935	RNA binding motif (RNP1, RRM) protein 3	RNA binding	Molecular function	8634703
STMN1	3925	stathmin 1	signal transducer activity	Molecular function	2917975
SATB1	6304	SATB homeobox 1	chromatin remodeling	Biological process	-
SKA1	220134	spindle and kinetochore associated complex subunit 1	mitotic nuclear division	Biological process	19289083
RAB6A	5870	RAB6A, member RAS oncogene family	peptidyl-cysteine methylation	Biological process	11121396
ILK	3611	integrin-linked kinase	negative regulation of neuron apoptotic process	Biological process	-
USP3	9960	ubiquitin specific peptidase 3	histone binding	Molecular function	17980597
OIP5	11339	Opa interacting protein 5	cell communication	Biological process	9466265
TRIM35	23087	tripartite motif containing 35	nucleus	Cellular component	-
CD37	951	CD37 molecule	extracellular exosome	Cellular component	20458337
SEMA6B	10501	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B	integral component of membrane	Cellular component	-
MAPKAP1	79109	mitogen-activated protein kinase associated protein 1	phosphatidylinositol-mediated signaling	Biological process	-
EDNRA	1909	endothelin receptor type A	phosphatidylinositol phospholipase C activity	Molecular function	8702836
CHRDL2	25884	chordin-like 2	ossification	Biological process	-
PPAPDC1A	196051	phosphatidic acid phosphatase type 2 domain containing 1A	phosphatidate phosphatase activity	Molecular function	17590538
OR3A1	4994	olfactory receptor, family 3, subfamily A, member 1	olfactory receptor activity	Molecular function	-
CPZ	8532	carboxypeptidase Z	Wnt signaling pathway	Biological process	-
POLR2D	5433	polymerase (RNA) II (DNA directed) polypeptide D	mRNA splicing, via spliceosome	Biological process	-
NFKB2	4791	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	12835724
LBH	81606	limb bud and heart development	transcription, DNA-templated	Biological process	-
SLC4A9	83697	solute carrier family 4, sodium bicarbonate cotransporter, member 9	transmembrane transport	Biological process	-
RRAGB	10325	Ras-related GTP binding B	cellular protein localization	Biological process	20381137
SLC9B1	150159	solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1	ion transmembrane transport	Biological process	-
BCCIP	56647	BRCA2 and CDKN1A interacting protein	neuroendocrine cell differentiation	Biological process	18440304
KIZ	55857	kizuna centrosomal protein	cytoplasm	Cellular component	-
PPARG	5468	peroxisome proliferator-activated receptor gamma	cytosol	Cellular component	-
ALOXE3	59344	arachidonate lipoxygenase 3	lyase activity	Molecular function	-
PLB1	151056	phospholipase B1	phototransduction, visible light	Biological process	-
DAB2IP	153090	DAB2 interacting protein	negative regulation of epithelial cell proliferation	Biological process	20154697
DCAF12	25853	DDB1 and CUL4 associated factor 12	centrosome	Cellular component	18957058
H2AFY	9555	H2A histone family, member Y	core promoter sequence-specific DNA binding	Molecular function	-
EPHA1	2041	EPH receptor A1	protein kinase binding	Molecular function	19118217
WWOX	51741	WW domain containing oxidoreductase	protein binding	Molecular function	15064722
KRR1	11103	KRR1, small subunit (SSU) processome component, homolog (yeast)	protein binding	Molecular function	19590578
CHPT1	56994	choline phosphotransferase 1	lipid metabolic process	Biological process	10893425
ZFYVE27	118813	zinc finger, FYVE domain containing 27	neuron projection development	Biological process	17082457
INS	3630	insulin	positive regulation of MAPK cascade	Biological process	11500939
UCP2	7351	uncoupling protein 2 (mitochondrial, proton carrier)	regulation of mitochondrial membrane potential	Biological process	-
SYNPR	132204	synaptoporin	cell junction	Cellular component	-
CDC5L	988	cell division cycle 5-like	DNA binding	Molecular function	8917598
ZBTB32	27033	zinc finger and BTB domain containing 32	protein binding	Molecular function	23088713
SNX2	6643	sorting nexin 2	lamellipodium morphogenesis	Biological process	20604901
TDGF1	6997	teratocarcinoma-derived growth factor 1	morphogenesis of a branching structure	Biological process	10070255
ALPP	250	alkaline phosphatase, placental	zinc ion binding	Molecular function	-
KIF14	9928	kinesin family member 14	regulation of cell migration	Biological process	23209302
INHBB	3625	inhibin, beta B	fat cell differentiation	Biological process	-
PALB2	79728	partner and localizer of BRCA2	negative regulation of apoptotic process	Biological process	-
ACTN4	81	actinin, alpha 4	retinoic acid receptor signaling pathway	Biological process	22351778
NPY5R	4889	neuropeptide Y receptor Y5	negative regulation of synaptic transmission, GABAergic	Biological process	-
CDKN1B	1027	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	Biological process	-
TSPAN3	10099	tetraspanin 3	extracellular exosome	Cellular component	19056867
RIPK4	54101	receptor-interacting serine-threonine kinase 4	protein serine/threonine kinase activity	Molecular function	-
MYLK2	85366	myosin light chain kinase 2	protein autophosphorylation	Biological process	21556048
PTPRG	5793	protein tyrosine phosphatase, receptor type, G	protein tyrosine phosphatase activity	Molecular function	19167335
MAP2K7	5609	mitogen-activated protein kinase kinase 7	MyD88-dependent toll-like receptor signaling pathway	Biological process	-
FZD6	8323	frizzled class receptor 6	apicolateral plasma membrane	Cellular component	-
AIPL1	23746	aryl hydrocarbon receptor interacting protein-like 1	retina homeostasis	Biological process	-
SRSF5	6430	serine/arginine-rich splicing factor 5	poly(A) RNA binding	Molecular function	22658674
LCAT	3931	lecithin-cholesterol acyltransferase	very-low-density lipoprotein particle remodeling	Biological process	15654758
TRIL	9865	TLR4 interactor with leucine-rich repeats	lipopolysaccharide binding	Molecular function	19710467
GPR50	9248	G protein-coupled receptor 50	melatonin receptor activity	Molecular function	-
NEUROD4	58158	neuronal differentiation 4	DNA binding	Molecular function	-
AP2A2	161	adaptor-related protein complex 2, alpha 2 subunit	cytoplasmic membrane-bounded vesicle	Cellular component	-
BCL11A	53335	B-cell CLL/lymphoma 11A (zinc finger protein)	positive regulation of neuron projection development	Biological process	19616629
SCMH1	22955	sex comb on midleg homolog 1 (Drosophila)	protein sumoylation	Biological process	-
BAG3	9531	BCL2-associated athanogene 3	negative regulation of apoptotic process	Biological process	10597216
ZCCHC6	79670	zinc finger, CCHC domain containing 6	zinc ion binding	Molecular function	-
KRTAP10-11	386678	keratin associated protein 10-11	protein binding	Molecular function	25416956
KIT	3815	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	myeloid progenitor cell differentiation	Biological process	-
NISCH	11188	nischarin	glucose metabolic process	Biological process	-
KLK4	9622	kallikrein-related peptidase 4	extracellular matrix disassembly	Biological process	-
IFNG	3458	interferon, gamma	extracellular space	Cellular component	-
MDM2	4193	MDM2 proto-oncogene, E3 ubiquitin protein ligase	fibroblast growth factor receptor signaling pathway	Biological process	-
DPP4	1803	dipeptidyl-peptidase 4	invadopodium membrane	Cellular component	16651416
SLC25A13	10165	solute carrier family 25 (aspartate/glutamate carrier), member 13	calcium ion binding	Molecular function	10642534
AKR1C3	8644	aldo-keto reductase family 1, member C3	geranylgeranyl reductase activity	Molecular function	21187079
BTK	695	Bruton agammaglobulinemia tyrosine kinase	identical protein binding	Molecular function	11577348
C9	735	complement component 9	extracellular region	Cellular component	-
IL36G	56300	interleukin 36, gamma	inflammatory response	Biological process	-
NEDD4	4734	neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase	negative regulation of sodium ion transmembrane transporter activity	Biological process	10642508
BMP2	650	bone morphogenetic protein 2	mesenchyme development	Biological process	20890042
C1QTNF1	114897	C1q and tumor necrosis factor related protein 1	positive regulation of MAPK cascade	Biological process	-
HSPB1	3315	heat shock 27kDa protein 1	cellular response to vascular endothelial growth factor stimulus	Biological process	18440775
HNRNPA1L2	144983	heterogeneous nuclear ribonucleoprotein A1-like 2	nucleotide binding	Molecular function	-
EPHA4	2043	EPH receptor A4	regulation of dendritic spine morphogenesis	Biological process	-
OR2T4	127074	olfactory receptor, family 2, subfamily T, member 4	G-protein coupled receptor signaling pathway	Biological process	-
CSF3	1440	colony stimulating factor 3 (granulocyte)	multicellular organismal development	Biological process	2420009
APOC1	341	apolipoprotein C-I	very-low-density lipoprotein particle clearance	Biological process	15576844
CLP1	10978	cleavage and polyadenylation factor I subunit 1	ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity	Molecular function	24766809
UCN2	90226	urocortin 2	cellular response to hypoxia	Biological process	-
ZNF217	7764	zinc finger protein 217	metal ion binding	Molecular function	-
SLC27A2	11001	solute carrier family 27 (fatty acid transporter), member 2	pristanate-CoA ligase activity	Molecular function	10198260
NR2E3	10002	nuclear receptor subfamily 2, group E, member 3	nucleus	Cellular component	10220376
PELI1	57162	pellino E3 ubiquitin protein ligase 1	innate immune response	Biological process	-
BIRC6	57448	baculoviral IAP repeat containing 6	negative regulation of apoptotic process	Biological process	10544019
EIF4E3	317649	eukaryotic translation initiation factor 4E family member 3	cytosol	Cellular component	-
EPS8L1	54869	EPS8-like 1	protein binding	Molecular function	17617578
EDEM3	80267	ER degradation enhancer, mannosidase alpha-like 3	calcium ion binding	Molecular function	-
PTPRH	5794	protein tyrosine phosphatase, receptor type, H	cytoplasm	Cellular component	-
SMG7	9887	SMG7 nonsense mediated mRNA decay factor	intermediate filament cytoskeleton	Cellular component	-
IL17F	112744	interleukin 17F	cytokine biosynthetic process	Biological process	11591732
STARD9	57519	StAR-related lipid transfer (START) domain containing 9	lipid binding	Molecular function	-
RARA	5914	retinoic acid receptor, alpha	retinoic acid-responsive element binding	Molecular function	19917671
NPHS1	4868	nephrosis 1, congenital, Finnish type (nephrin)	JNK cascade	Biological process	-
RAB29	8934	RAB29, member RAS oncogene family	retrograde transport, plasma membrane to Golgi	Biological process	24788816
TNFSF18	8995	tumor necrosis factor (ligand) superfamily, member 18	positive regulation of leukocyte migration	Biological process	23892569
SLC24A3	57419	solute carrier family 24 (sodium/potassium/calcium exchanger), member 3	potassium ion transport	Biological process	-
PGLYRP1	8993	peptidoglycan recognition protein 1	zinc ion binding	Molecular function	-
ZNF689	115509	zinc finger protein 689	nucleus	Cellular component	-
MCF2	4168	MCF.2 cell line derived transforming sequence	cytoskeleton	Cellular component	3056717
LIN28A	79727	lin-28 homolog A (C. elegans)	miRNA binding	Molecular function	-
BMP2	650	bone morphogenetic protein 2	protein binding	Molecular function	10881198
HIST1H3G	8355	histone cluster 1, H3g	nucleosome	Cellular component	21636898
FGF2	2247	fibroblast growth factor 2 (basic)	negative regulation of cell death	Biological process	12631064
ISG15	9636	ISG15 ubiquitin-like modifier	negative regulation of viral genome replication	Biological process	19357168
ATP6V0A1	535	ATPase, H+ transporting, lysosomal V0 subunit a1	vacuolar proton-transporting V-type ATPase complex assembly	Biological process	-
AIF1	199	allograft inflammatory factor 1	positive regulation of T cell proliferation	Biological process	16049345
ANG	283	angiogenin, ribonuclease, RNase A family, 5	positive regulation of endothelial cell proliferation	Biological process	9122172
CRLF2	64109	cytokine receptor-like factor 2	integral component of membrane	Cellular component	-
YY1	7528	YY1 transcription factor	sequence-specific DNA binding transcription factor activity	Molecular function	1946405
ZNF24	7572	zinc finger protein 24	negative regulation of transcription, DNA-templated	Biological process	10585455
MAP3K11	4296	mitogen-activated protein kinase kinase kinase 11	microtubule	Cellular component	12529434
OR8H2	390151	olfactory receptor, family 8, subfamily H, member 2	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
ACAA2	10449	acetyl-CoA acyltransferase 2	protein binding	Molecular function	18371312
STRC	161497	stereocilin	auditory receptor cell stereocilium organization	Biological process	-
TONSL	4796	tonsoku-like, DNA repair protein	double-strand break repair via homologous recombination	Biological process	21055983
H2AFZ	3015	H2A histone family, member Z	cellular response to estradiol stimulus	Biological process	23637611
ROCK2	9475	Rho-associated, coiled-coil containing protein kinase 2	cytosol	Cellular component	-
TCP11	6954	t-complex 11, testis-specific	cell differentiation	Biological process	-
SMAD3	4088	SMAD family member 3	negative regulation of apoptotic process	Biological process	-
KCNMB2	10242	potassium channel subfamily M regulatory beta subunit 2	integral component of plasma membrane	Cellular component	10692449
TMSB4Y	9087	thymosin beta 4, Y-linked	cytoplasm	Cellular component	-
KMO	8564	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	extracellular exosome	Cellular component	23376485
GRIK1	2897	glutamate receptor, ionotropic, kainate 1	ionotropic glutamate receptor signaling pathway	Biological process	10580501
TJP2	9414	tight junction protein 2	protein domain specific binding	Molecular function	23885123
ARSF	416	arylsulfatase F	arylsulfatase activity	Molecular function	9192838
CPEB1	64506	cytoplasmic polyadenylation element binding protein 1	negative regulation of cytoplasmic translation	Biological process	18752464
DLGAP5	9787	discs, large (Drosophila) homolog-associated protein 5	nucleus	Cellular component	-
MICAL1	64780	microtubule associated monooxygenase, calponin and LIM domain containing 1	protein binding	Molecular function	11827972
RAB3IL1	5866	RAB3A interacting protein (rabin3)-like 1	protein binding	Molecular function	16189514
DLG5	9231	discs, large homolog 5 (Drosophila)	intracellular signal transduction	Biological process	12353226
FLCN	201163	folliculin	plasma membrane	Cellular component	-
TET2	54790	tet methylcytosine dioxygenase 2	cytosine metabolic process	Biological process	-
TIAL1	7073	TIA1 cytotoxic granule-associated RNA binding protein-like 1	defense response	Biological process	1326761
ZNF335	63925	zinc finger protein 335	RNA polymerase II core promoter sequence-specific DNA binding	Molecular function	-
GRIA2	2891	glutamate receptor, ionotropic, AMPA 2	synaptic transmission, glutamatergic	Biological process	-
RPS15	6209	ribosomal protein S15	membrane	Cellular component	16210410
BEST4	266675	bestrophin 4	chloride transmembrane transport	Biological process	-
ETS1	2113	v-ets avian erythroblastosis virus E26 oncogene homolog 1	positive regulation of cellular component movement	Biological process	15247905
OTULIN	90268	OTU deubiquitinase with linear linkage specificity	ubiquitin-specific protease activity	Molecular function	23746843
ELL	8178	elongation factor RNA polymerase II	phosphatase binding	Molecular function	19389623
POLR2G	5436	polymerase (RNA) II (DNA directed) polypeptide G	nucleus	Cellular component	9852112
JAM3	83700	junctional adhesion molecule 3	paranodal junction	Cellular component	-
PSMD4	5710	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	Biological process	-
STRBP	55342	spermatid perinuclear RNA binding protein	cytoplasm	Cellular component	-
EDN2	1907	endothelin 2	energy homeostasis	Biological process	-
SEC31A	22872	SEC31 homolog A (S. cerevisiae)	protein transport	Biological process	-
MUC19	283463	mucin 19, oligomeric	extracellular exosome	Cellular component	23376485
ST8SIA4	7903	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity	Molecular function	10766765
ZDHHC16	84287	zinc finger, DHHC-type containing 16	palmitoyltransferase activity	Molecular function	23034182
PTPN2	5771	protein tyrosine phosphatase, non-receptor type 2	receptor tyrosine kinase binding	Molecular function	18819921
BRIP1	83990	BRCA1 interacting protein C-terminal helicase 1	nuclear membrane	Cellular component	-
MKL1	57591	megakaryoblastic leukemia (translocation) 1	protein binding	Molecular function	12397177
PNPO	55163	pyridoxamine 5'-phosphate oxidase	vitamin B6 metabolic process	Biological process	-
PSMB7	5695	proteasome (prosome, macropain) subunit, beta type, 7	proteasomal ubiquitin-independent protein catabolic process	Biological process	-
GFI1	2672	growth factor independent 1 transcription repressor	positive regulation of cell fate specification	Biological process	-
FOXF2	2295	forkhead box F2	positive regulation of transcription, DNA-templated	Biological process	8626802
CSF1R	1436	colony stimulating factor 1 receptor	positive regulation of protein serine/threonine kinase activity	Biological process	-
HILPDA	29923	hypoxia inducible lipid droplet-associated	positive regulation of lipid storage	Biological process	20624928
SMAD7	4092	SMAD family member 7	activin binding	Molecular function	16720724
SLC12A1	6557	solute carrier family 12 (sodium/potassium/chloride transporter), member 1	integral component of membrane	Cellular component	-
PTPRD	5789	protein tyrosine phosphatase, receptor type, D	transmembrane receptor protein tyrosine phosphatase activity	Molecular function	7896816
PLEKHA1	59338	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	phosphatidylinositol 3-kinase signaling	Biological process	12101241
OR5M8	219484	olfactory receptor, family 5, subfamily M, member 8	integral component of plasma membrane	Cellular component	-
BAZ2B	29994	bromodomain adjacent to zinc finger domain, 2B	regulation of transcription, DNA-templated	Biological process	10662543
GOSR1	9527	golgi SNAP receptor complex member 1	integral component of membrane	Cellular component	-
JKAMP	51528	JNK1/MAPK8-associated membrane protein	endoplasmic reticulum membrane	Cellular component	-
MPG	4350	N-methylpurine-DNA glycosylase	DNA-7-methylguanine glycosylase activity	Molecular function	-
CEACAM8	1088	carcinoembryonic antigen-related cell adhesion molecule 8	immune response	Biological process	2208113
STX16	8675	syntaxin 16	endomembrane system	Cellular component	-
NANOGP8	388112	Nanog homeobox pseudogene 8	sequence-specific DNA binding	Molecular function	-
FLNA	2316	filamin A, alpha	early endosome to late endosome transport	Biological process	-
SPTA1	6708	spectrin, alpha, erythrocytic 1	spectrin	Cellular component	1634521
SYT17	51760	synaptotagmin XVII	plasma membrane	Cellular component	-
NPY1R	4886	neuropeptide Y receptor Y1	neuropeptide Y receptor activity	Molecular function	1317848
EPHA3	2042	EPH receptor A3	axon guidance	Biological process	-
PIK3C3	5289	phosphatidylinositol 3-kinase, catalytic subunit type 3	phosphatidylinositol 3-kinase complex, class III	Cellular component	-
OXSR1	9943	oxidative stress responsive 1	ATP binding	Molecular function	14707132
P2RY1	5028	purinergic receptor P2Y, G-protein coupled, 1	cell surface	Cellular component	23382103
MOS	4342	v-mos Moloney murine sarcoma viral oncogene homolog	protein binding	Molecular function	25416956
DIRAS1	148252	DIRAS family, GTP-binding RAS-like 1	intracellular	Cellular component	-
RPS6	6194	ribosomal protein S6	positive regulation of apoptotic process	Biological process	18362888
AP3B1	8546	adaptor-related protein complex 3, beta 1 subunit	antigen processing and presentation, exogenous lipid antigen via MHC class Ib	Biological process	-
ADORA1	134	adenosine A1 receptor	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway	Biological process	-
RIMKLA	284716	ribosomal modification protein rimK-like family member A	cellular protein modification process	Biological process	-
MRPS25	64432	mitochondrial ribosomal protein S25	mitochondrial translational termination	Biological process	-
TMED10	10972	transmembrane emp24-like trafficking protein 10 (yeast)	plasma membrane	Cellular component	-
TSPAN12	23554	tetraspanin 12	cell surface receptor signaling pathway	Biological process	-
NUP93	9688	nucleoporin 93kDa	viral life cycle	Biological process	-
DCTN2	10540	dynactin 2 (p50)	G2/M transition of mitotic cell cycle	Biological process	-
OR10G6	79490	olfactory receptor, family 10, subfamily G, member 6	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
SRCAP	10847	Snf2-related CREBBP activator protein	helicase activity	Molecular function	-
PLXNB2	23654	plexin B2	neural tube closure	Biological process	-
NFKBIA	4792	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	innate immune response	Biological process	-
CPNE5	57699	copine V	neuron projection	Cellular component	-
MED30	90390	mediator complex subunit 30	protein binding	Molecular function	21784977
PLEC	5339	plectin	hemidesmosome	Cellular component	12482924
WDR55	54853	WD repeat domain 55	biological_process	Biological process	-
PSMB1	5689	proteasome (prosome, macropain) subunit, beta type, 1	nucleus	Cellular component	-
SCARB1	949	scavenger receptor class B, member 1	positive regulation of endothelial cell migration	Biological process	17574123
SNRPC	6631	small nuclear ribonucleoprotein polypeptide C	protein binding	Molecular function	12486009
MAPKAPK5	8550	mitogen-activated protein kinase-activated protein kinase 5	activation of MAPK activity	Biological process	9628874
MCCC1	56922	methylcrotonoyl-CoA carboxylase 1 (alpha)	leucine catabolic process	Biological process	11170888
ARV1	64801	ARV1 homolog (S. cerevisiae)	integral component of membrane	Cellular component	-
NUDT19	390916	nudix (nucleoside diphosphate linked moiety X)-type motif 19	mitochondrion	Cellular component	-
DMRT3	58524	doublesex and mab-3 related transcription factor 3	regulation of transcription, DNA-templated	Biological process	-
CLASP2	23122	cytoplasmic linker associated protein 2	negative regulation of microtubule depolymerization	Biological process	11290329
RAC1	5879	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	dopaminergic neuron differentiation	Biological process	-
BRINP3	339479	bone morphogenetic protein/retinoic acid inducible neural-specific 3	positive regulation of neuron differentiation	Biological process	-
CDH1	999	cadherin 1, type 1, E-cadherin (epithelial)	lamellipodium	Cellular component	24046456
HBA1	3039	hemoglobin, alpha 1	extracellular region	Cellular component	-
HNRNPC	3183	heterogeneous nuclear ribonucleoprotein C (C1/C2)	membrane	Cellular component	16210410
MAP3K10	4294	mitogen-activated protein kinase kinase kinase 10	ATP binding	Molecular function	-
UBE2V1	7335	ubiquitin-conjugating enzyme E2 variant 1	toll-like receptor 2 signaling pathway	Biological process	-
OR2A7	401427	olfactory receptor, family 2, subfamily A, member 7	integral component of membrane	Cellular component	-
RET	5979	ret proto-oncogene	innervation	Biological process	-
IL17F	112744	interleukin 17F	regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	Biological process	11574464
PDGFA	5154	platelet-derived growth factor alpha polypeptide	positive regulation of DNA replication	Biological process	10806482
RAB7B	338382	RAB7B, member RAS oncogene family	late endosome to Golgi transport	Biological process	20375062
CRYBA1	1411	crystallin, beta A1	protein homodimerization activity	Molecular function	-
PRICKLE1	144165	prickle homolog 1 (Drosophila)	protein binding	Molecular function	14645515
COL2A1	1280	collagen, type II, alpha 1	collagen catabolic process	Biological process	-
IFNA16	3449	interferon, alpha 16	defense response to virus	Biological process	-
AGFG1	3267	ArfGAP with FG repeats 1	DNA binding	Molecular function	-
VTCN1	79679	V-set domain containing T cell activation inhibitor 1	negative regulation of T cell activation	Biological process	-
POLR3C	10623	polymerase (RNA) III (DNA directed) polypeptide C (62kD)	defense response to virus	Biological process	-
BACE2	25825	beta-site APP-cleaving enzyme 2	endosome	Cellular component	-
MDM2	4193	MDM2 proto-oncogene, E3 ubiquitin protein ligase	synapse	Cellular component	-
ADH6	130	alcohol dehydrogenase 6 (class V)	alcohol dehydrogenase activity, zinc-dependent	Molecular function	-
SRSF6	6431	serine/arginine-rich splicing factor 6	gene expression	Biological process	-
RNF111	54778	ring finger protein 111	ubiquitin-dependent SMAD protein catabolic process	Biological process	-
MYO1F	4542	myosin IF	neutrophil degranulation	Biological process	-
CFAP221	200373	cilia and flagella associated protein 221	cilium morphogenesis	Biological process	-
MASP2	10747	mannan-binding lectin serine peptidase 2	extracellular region	Cellular component	-
SUV39H1	6839	suppressor of variegation 3-9 homolog 1 (Drosophila)	gene expression	Biological process	-
GALNT5	11227	polypeptide N-acetylgalactosaminyltransferase 5	polypeptide N-acetylgalactosaminyltransferase activity	Molecular function	10545594
MAST3	23031	microtubule associated serine/threonine kinase 3	magnesium ion binding	Molecular function	-
SNX9	51429	sorting nexin 9	protein binding	Molecular function	10531379
NETO1	81832	neuropilin (NRP) and tolloid (TLL)-like 1	postsynaptic density	Cellular component	-
IGFBP4	3487	insulin-like growth factor binding protein 4	cell proliferation	Biological process	1377672
ANKRA2	57763	ankyrin repeat, family A (RFXANK-like), 2	protein binding	Molecular function	25416956
SNX3	8724	sorting nexin 3	early phagosome	Cellular component	23237080
CDKN2A	1029	cyclin-dependent kinase inhibitor 2A	regulation of protein stability	Biological process	-
PPOX	5498	protoporphyrinogen oxidase	response to drug	Biological process	-
GCK	2645	glucokinase (hexokinase 4)	glucose binding	Molecular function	12941786
NFATC4	4776	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	-
FBXO11	80204	F-box protein 11	chromosome	Cellular component	-
XRCC2	7516	X-ray repair complementing defective repair in Chinese hamster cells 2	regulation of fibroblast apoptotic process	Biological process	-
STX1B	112755	syntaxin 1B	synaptic vesicle fusion to presynaptic membrane	Biological process	-
TTC19	54902	tetratricopeptide repeat domain 19	mitochondrion	Cellular component	-
RHOQ	23433	ras homolog family member Q	Golgi-associated vesicle membrane	Cellular component	-
USP17L1	401447	ubiquitin specific peptidase 17-like family member 1	ubiquitin-dependent protein catabolic process	Biological process	-
ADRA2C	152	adrenoceptor alpha 2C	protein heterodimerization activity	Molecular function	16605244
PROX1	5629	prospero homeobox 1	olfactory placode formation	Biological process	11789987
CKAP5	9793	cytoskeleton associated protein 5	centrosome	Cellular component	14718566
ERBB4	2066	erb-b2 receptor tyrosine kinase 4	positive regulation of transcription, DNA-templated	Biological process	15534001
SNPH	9751	syntaphilin	syntaxin-1 binding	Molecular function	10707983
JAK2	3717	Janus kinase 2	positive regulation of cell migration	Biological process	-
LDB1	8861	LIM domain binding 1	nuclear chromatin	Cellular component	20855495
MPEG1	219972	macrophage expressed 1	integral component of membrane	Cellular component	-
TRBV12-3	28577	T cell receptor beta variable 12-3	MHC protein binding	Molecular function	6336315
SP4	6671	Sp4 transcription factor	intercellular bridge	Cellular component	-
PTK2B	2185	protein tyrosine kinase 2 beta	positive regulation of protein kinase activity	Biological process	7544443
TNFRSF1B	7133	tumor necrosis factor receptor superfamily, member 1B	integral component of membrane	Cellular component	-
POU2F3	25833	POU class 2 homeobox 3	epidermis development	Biological process	10473598
NUP88	4927	nucleoporin 88kDa	viral life cycle	Biological process	-
WDR45	11152	WD repeat domain 45	autophagy	Biological process	23435086
SARS	6301	seryl-tRNA synthetase	translation	Biological process	9431993
TTC30B	150737	tetratricopeptide repeat domain 30B	cilium	Cellular component	-
ACTN3	89	actinin, alpha 3 (gene/pseudogene)	protein homodimerization activity	Molecular function	15841212
MRPS24	64951	mitochondrial ribosomal protein S24	biological_process	Biological process	-
PEX3	8504	peroxisomal biogenesis factor 3	amino acid transmembrane transport	Biological process	-
SIN3A	25942	SIN3 transcription regulator family member A	negative regulation of gene expression, epigenetic	Biological process	-
CNST	163882	consortin, connexin sorting protein	phosphatase binding	Molecular function	19389623
SELE	6401	selectin E	leukocyte migration involved in inflammatory response	Biological process	18029551
STAR	6770	steroidogenic acute regulatory protein	positive regulation of gene expression	Biological process	-
HNRNPA2B1	3181	heterogeneous nuclear ribonucleoprotein A2/B1	RNA splicing	Biological process	-
NSF	4905	N-ethylmaleimide-sensitive factor	postsynaptic density	Cellular component	-
FUT8	2530	fucosyltransferase 8 (alpha (1,6) fucosyltransferase)	cell migration	Biological process	-
CLNS1A	1207	chloride channel, nucleotide-sensitive, 1A	gene expression	Biological process	-
ZSCAN10	84891	zinc finger and SCAN domain containing 10	nucleoplasm	Cellular component	-
SGOL1	151648	shugoshin-like 1 (S. pombe)	mitotic cohesin complex	Cellular component	18084284
CES4A	283848	carboxylesterase 4A	carboxylic ester hydrolase activity	Molecular function	-
CTH	1491	cystathionine gamma-lyase	cytoplasm	Cellular component	-
ADRB1	153	adrenoceptor beta 1	positive regulation of the force of heart contraction by norepinephrine	Biological process	-
FAF1	11124	Fas (TNFRSF6) associated factor 1	heat shock protein binding	Molecular function	15596450
SLCO2B1	11309	solute carrier organic anion transporter family, member 2B1	integral component of membrane	Cellular component	-
POU5F1B	5462	POU class 5 homeobox 1B	sequence-specific DNA binding	Molecular function	-
ABCA5	23461	ATP-binding cassette, sub-family A (ABC1), member 5	late endosome membrane	Cellular component	-
RRN3	54700	RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)	transcription from RNA polymerase I promoter	Biological process	-
PTEN	5728	phosphatase and tensin homolog	response to arsenic-containing substance	Biological process	-
MTRNR2L9	100463487	MT-RNR2-like 9	cytoplasm	Cellular component	-
UNC50	25972	unc-50 homolog (C. elegans)	RNA binding	Molecular function	-
FURIN	5045	furin (paired basic amino acid cleaving enzyme)	protein processing	Biological process	15899807
TAF4	6874	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa	nucleoplasm	Cellular component	-
PSME1	5720	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)	nucleoplasm	Cellular component	-
HSPA5	3309	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	activation of signaling protein activity involved in unfolded protein response	Biological process	-
CPT1B	1375	carnitine palmitoyltransferase 1B (muscle)	cellular lipid metabolic process	Biological process	-
SLC35A3	23443	solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3	UDP-N-acetylglucosamine transmembrane transporter activity	Molecular function	10393322
TFPT	29844	TCF3 (E2A) fusion partner (in childhood Leukemia)	nucleus	Cellular component	-
NANS	54187	N-acetylneuraminic acid synthase	N-acetylneuraminate synthase activity	Molecular function	-
TGFB1	7040	transforming growth factor, beta 1	negative regulation of macrophage cytokine production	Biological process	20875417
SLC6A5	9152	solute carrier family 6 (neurotransmitter transporter), member 5	neurotransmitter transport	Biological process	-
CDKN1B	1027	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	fibroblast growth factor receptor signaling pathway	Biological process	-
OTOP3	347741	otopetrin 3	metal ion binding	Molecular function	-
SUCLA2	8803	succinate-CoA ligase, ADP-forming, beta subunit	ATP binding	Molecular function	-
ID1	3397	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	transcription, DNA-templated	Biological process	-
USH1C	10083	Usher syndrome 1C (autosomal recessive, severe)	cytoplasm	Cellular component	10209257
RTN4RL1	146760	reticulon 4 receptor-like 1	axon regeneration	Biological process	14664809
POP7	10248	processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)	cytoplasm	Cellular component	-
PLA2G2A	5320	phospholipase A2, group IIA (platelets, synovial fluid)	phosphatidic acid metabolic process	Biological process	9032461
GLG1	2734	golgi glycoprotein 1	bone morphogenesis	Biological process	-
CSGALNACT2	55454	chondroitin sulfate N-acetylgalactosaminyltransferase 2	acetylgalactosaminyltransferase activity	Molecular function	11788602
TCTN1	79600	tectonic family member 1	central nervous system interneuron axonogenesis	Biological process	-
LPAR4	2846	lysophosphatidic acid receptor 4	G-protein coupled receptor activity	Molecular function	-
BMP2	650	bone morphogenetic protein 2	cell surface	Cellular component	22227436
FOXK1	221937	forkhead box K1	negative regulation of transcription, DNA-templated	Biological process	-
CD9	928	CD9 molecule	extracellular vesicle	Cellular component	24769233
FGF10	2255	fibroblast growth factor 10	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling	Biological process	-
RNASE10	338879	ribonuclease, RNase A family, 10 (non-active)	single fertilization	Biological process	-
TXNDC11	51061	thioredoxin domain containing 11	response to endoplasmic reticulum stress	Biological process	-
AMACR	23600	alpha-methylacyl-CoA racemase	cytoplasm	Cellular component	15941950
STXBP3	6814	syntaxin binding protein 3	membrane organization	Biological process	-
RNF41	10193	ring finger protein 41, E3 ubiquitin protein ligase	protein tag	Molecular function	-
SRP54	6729	signal recognition particle 54kDa	cellular protein metabolic process	Biological process	-
OCRL	4952	oculocerebrorenal syndrome of Lowe	lipid metabolic process	Biological process	1321346
PIK3CA	5290	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	T cell costimulation	Biological process	-
BRSK2	9024	BR serine/threonine kinase 2	exocytosis	Biological process	-
E2F1	1869	E2F transcription factor 1	sequence-specific DNA binding	Molecular function	-
RAMP2	10266	receptor (G protein-coupled) activity modifying protein 2	protein binding	Molecular function	20596610
NR4A2	4929	nuclear receptor subfamily 4, group A, member 2	cellular response to oxidative stress	Biological process	-
CCR5	1234	chemokine (C-C motif) receptor 5 (gene/pseudogene)	C-C chemokine binding	Molecular function	10679098
RPH3AL	9501	rabphilin 3A-like (without C2 domains)	negative regulation of G-protein coupled receptor protein signaling pathway	Biological process	-
GJB6	10804	gap junction protein, beta 6, 30kDa	apoptotic process	Biological process	-
CREM	1390	cAMP responsive element modulator	glycosphingolipid metabolic process	Biological process	-
ADCY9	115	adenylate cyclase 9	water transport	Biological process	-
PLA2G4F	255189	phospholipase A2, group IVF	phospholipid catabolic process	Biological process	-
TNFRSF1A	7132	tumor necrosis factor receptor superfamily, member 1A	cell surface	Cellular component	-
DEFB119	245932	defensin, beta 119	innate immune response	Biological process	-
DIAPH1	1729	diaphanous-related formin 1	small GTPase mediated signal transduction	Biological process	-
STRAP	11171	serine/threonine kinase receptor associated protein	negative regulation of transforming growth factor beta receptor signaling pathway	Biological process	-
KRTAP13-2	337959	keratin associated protein 13-2	intermediate filament	Cellular component	-
KCNQ1	3784	potassium channel, voltage gated KQT-like subfamily Q, member 1	early endosome	Cellular component	21957902
EHD1	10938	EH-domain containing 1	ATP binding	Molecular function	-
MS4A2	2206	membrane-spanning 4-domains, subfamily A, member 2	inflammatory response	Biological process	-
AP4B1	10717	adaptor-related protein complex 4, beta 1 subunit	coated pit	Cellular component	-
MACC1	346389	metastasis associated in colon cancer 1	positive regulation of cell division	Biological process	-
AKT1	207	v-akt murine thymoma viral oncogene homolog 1	protein autophosphorylation	Biological process	16280327
MAP3K11	4296	mitogen-activated protein kinase kinase kinase 11	cytoplasm	Cellular component	-
RABAC1	10567	Rab acceptor 1 (prenylated)	synaptic vesicle	Cellular component	-
TIMMDC1	51300	translocase of inner mitochondrial membrane domain containing 1	mitochondrial membrane	Cellular component	-
ESF1	51575	ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)	regulation of transcription, DNA-templated	Biological process	-
CMIP	80790	c-Maf inducing protein	cytoplasm	Cellular component	-
ASTN1	460	astrotactin 1	external side of plasma membrane	Cellular component	-
FOXD1	2297	forkhead box D1	sequence-specific DNA binding	Molecular function	7957066
RIPK2	8767	receptor-interacting serine-threonine kinase 2	response to exogenous dsRNA	Biological process	-
ATP2A1	487	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	H zone	Cellular component	1329967
SFN	2810	stratifin	keratinocyte development	Biological process	-
ST3GAL6	10402	ST3 beta-galactoside alpha-2,3-sialyltransferase 6	Golgi membrane	Cellular component	-
PRAMEF19	645414	PRAME family member 19	negative regulation of transcription, DNA-templated	Biological process	-
CDX2	1045	caudal type homeobox 2	anterior/posterior pattern specification	Biological process	-
BRD2	6046	bromodomain containing 2	lysine-acetylated histone binding	Molecular function	18406326
PNPT1	87178	polyribonucleotide nucleotidyltransferase 1	membrane	Cellular component	-
PLCE1	51196	phospholipase C, epsilon 1	Ras protein signal transduction	Biological process	11022048
AHR	196	aryl hydrocarbon receptor	signal transducer activity	Molecular function	-
PARS2	25973	prolyl-tRNA synthetase 2, mitochondrial (putative)	prolyl-tRNA aminoacylation	Biological process	-
MST1R	4486	macrophage stimulating 1 receptor	macrophage colony-stimulating factor signaling pathway	Biological process	9045873
RAMP2	10266	receptor (G protein-coupled) activity modifying protein 2	cAMP biosynthetic process	Biological process	20074556
XPOT	11260	exportin, tRNA	tRNA binding	Molecular function	9660920
ZBTB16	7704	zinc finger and BTB domain containing 16	cytosol	Cellular component	-
SLC23A1	9963	solute carrier family 23 (ascorbic acid transporter), member 1	vitamin transmembrane transport	Biological process	-
ATAD2	29028	ATPase family, AAA domain containing 2	nucleoplasm	Cellular component	-
UGGT1	56886	UDP-glucose glycoprotein glucosyltransferase 1	UDP-glucosylation	Biological process	-
APOC2	344	apolipoprotein C-II	intermediate-density lipoprotein particle	Cellular component	17336988
MICB	4277	MHC class I polypeptide-related sequence B	viral process	Biological process	-
CD3E	916	CD3e molecule, epsilon (CD3-TCR complex)	protein complex assembly	Biological process	9886373
GNB3	2784	guanine nucleotide binding protein (G protein), beta polypeptide 3	small molecule metabolic process	Biological process	-
F3	2152	coagulation factor III (thromboplastin, tissue factor)	protein binding	Molecular function	15522303
SLC2A2	6514	solute carrier family 2 (facilitated glucose transporter), member 2	integral component of plasma membrane	Cellular component	8027028
STX10	8677	syntaxin 10	early endosome to Golgi transport	Biological process	16154903
STX16	8675	syntaxin 16	trans-Golgi network	Cellular component	16154903
PLA2G6	8398	phospholipase A2, group VI (cytosolic, calcium-independent)	positive regulation of insulin secretion involved in cellular response to glucose stimulus	Biological process	-
SLC7A6	9057	solute carrier family 7 (amino acid transporter light chain, y+L system), member 6	antiporter activity	Molecular function	-
SLC9A2	6549	solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2	hydrogen ion transmembrane transport	Biological process	-
APLP2	334	amyloid beta (A4) precursor-like protein 2	G-protein coupled receptor signaling pathway	Biological process	8220435
PTGIS	5740	prostaglandin I2 (prostacyclin) synthase	monooxygenase activity	Molecular function	-
PRAMEF9	343070	PRAME family member 9	positive regulation of cell proliferation	Biological process	-
TPR	7175	translocated promoter region, nuclear basket protein	protein homodimerization activity	Molecular function	11514627
PDSS2	57107	prenyl (decaprenyl) diphosphate synthase, subunit 2	protein heterotetramerization	Biological process	-
TRAF6	7189	TNF receptor-associated factor 6, E3 ubiquitin protein ligase	neural tube closure	Biological process	-
ARNT2	9915	aryl-hydrocarbon receptor nuclear translocator 2	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
ACTC1	70	actin, alpha, cardiac muscle 1	skeletal muscle thin filament assembly	Biological process	-
ZFP36	7538	ZFP36 ring finger protein	nuclear-transcribed mRNA poly(A) tail shortening	Biological process	23644599
CHMP4A	29082	charged multivesicular body protein 4A	late endosome membrane	Cellular component	-
ZFP42	132625	ZFP42 zinc finger protein	cytoplasm	Cellular component	16344273
HIST1H2BJ	8970	histone cluster 1, H2bj	nuclear nucleosome	Cellular component	-
SCN1A	6323	sodium channel, voltage gated, type I alpha subunit	T-tubule	Cellular component	-
OR1J1	347168	olfactory receptor, family 1, subfamily J, member 1	G-protein coupled receptor signaling pathway	Biological process	-
ZNF705E	100131539	zinc finger protein 705E	transcription, DNA-templated	Biological process	-
MXRA5	25878	matrix-remodelling associated 5	molecular_function	Molecular function	-
VPS33A	65082	vacuolar protein sorting 33 homolog A (S. cerevisiae)	HOPS complex	Cellular component	19109425
TBX5	6910	T-box 5	endocardial cushion development	Biological process	-
Mar-05	54708	membrane-associated ring finger (C3HC4) 5	positive regulation of mitochondrial fission	Biological process	20103533
Mar-02	51257	membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase	lysosomal membrane	Cellular component	-
YWHAB	7529	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta	protein C-terminus binding	Molecular function	-
MAP3K11	4296	mitogen-activated protein kinase kinase kinase 11	protein kinase activity	Molecular function	10799501
ALX4	60529	ALX homeobox 4	embryonic skeletal system morphogenesis	Biological process	-
POLR2G	5436	polymerase (RNA) II (DNA directed) polypeptide G	transcription-coupled nucleotide-excision repair	Biological process	-
LIPC	3990	lipase, hepatic	low-density lipoprotein particle remodeling	Biological process	3244012
GPN2	54707	GPN-loop GTPase 2	cellular_component	Cellular component	-
LCN2	3934	lipocalin 2	cellular iron ion homeostasis	Biological process	-
ATXN10	25814	ataxin 10	neuronal cell body	Cellular component	15201271
TERT	7015	telomerase reverse transcriptase	positive regulation of Wnt signaling pathway	Biological process	19571879
NCDN	23154	neurochondrin	membrane	Cellular component	19946888
HSPA8	3312	heat shock 70kDa protein 8	viral process	Biological process	-
VPS25	84313	vacuolar protein sorting 25 homolog (S. cerevisiae)	regulation of transcription, DNA-templated	Biological process	-
KCNJ10	3766	potassium channel, inwardly rectifying subfamily J, member 10	potassium ion transport	Biological process	8995301
POU3F4	5456	POU class 3 homeobox 4	negative regulation of mesenchymal cell apoptotic process	Biological process	-
IGF1R	3480	insulin-like growth factor 1 receptor	axonogenesis	Biological process	-
VAV1	7409	vav 1 guanine nucleotide exchange factor	cytosol	Cellular component	-
MAGI3	260425	membrane associated guanylate kinase, WW and PDZ domain containing 3	frizzled binding	Molecular function	-
KCNA1	3736	potassium channel, voltage gated shaker related subfamily A, member 1	potassium ion transport	Biological process	8845167
KCNQ2	3785	potassium channel, voltage gated KQT-like subfamily Q, member 2	node of Ranvier	Cellular component	16525039
FMN1	342184	formin 1	adherens junction	Cellular component	-
RPS8	6202	ribosomal protein S8	viral process	Biological process	-
ZNF83	55769	zinc finger protein 83	sequence-specific DNA binding transcription factor activity	Molecular function	-
MTCL1	23255	microtubule crosslinking factor 1	spindle pole	Cellular component	23902687
PPARGC1A	10891	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	circadian regulation of gene expression	Biological process	-
SARS2	54938	seryl-tRNA synthetase 2, mitochondrial	poly(A) RNA binding	Molecular function	22681889
CTDSP1	58190	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1	negative regulation of protein phosphorylation	Biological process	-
RPS19	6223	ribosomal protein S19	protein homodimerization activity	Molecular function	11226885
MAP2K6	5608	mitogen-activated protein kinase kinase 6	apoptotic process	Biological process	-
MYLK	4638	myosin light chain kinase	stress fiber	Cellular component	15020676
WASF2	10163	WAS protein family, member 2	actin cytoskeleton	Cellular component	10970852
GTF3C2	2976	general transcription factor IIIC, polypeptide 2, beta 110kDa	transcription, DNA-templated	Biological process	17409385
PER1	5187	period circadian clock 1	negative regulation of glucocorticoid receptor signaling pathway	Biological process	-
ENO1	2023	enolase 1, (alpha)	plasma membrane	Cellular component	-
KLF16	83855	Kruppel-like factor 16	DNA binding	Molecular function	-
RALYL	138046	RALY RNA binding protein-like	identical protein binding	Molecular function	16189514
ADCY5	111	adenylate cyclase 5	adenosine receptor signaling pathway	Biological process	-
CASP9	842	caspase 9, apoptosis-related cysteine peptidase	cellular response to DNA damage stimulus	Biological process	15657060
SDHA	6389	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	cellular metabolic process	Biological process	-
OR2T33	391195	olfactory receptor, family 2, subfamily T, member 33	plasma membrane	Cellular component	-
ZNF418	147686	zinc finger protein 418	regulation of transcription, DNA-templated	Biological process	-
NRSN2	80023	neurensin 2	transport vesicle	Cellular component	-
ERCC2	2068	excision repair cross-complementation group 2	DNA-dependent ATPase activity	Molecular function	8663148
DYNC1I2	1781	dynein, cytoplasmic 1, intermediate chain 2	protein binding	Molecular function	25416956
GSK3B	2932	glycogen synthase kinase 3 beta	axon guidance	Biological process	-
FGF10	2255	fibroblast growth factor 10	positive regulation of ATPase activity	Biological process	12804770
CDC42	998	cell division cycle 42	actin filament bundle assembly	Biological process	-
SLC22A6	9356	solute carrier family 22 (organic anion transporter), member 6	protein homodimerization activity	Molecular function	-
ENTPD3	956	ectonucleoside triphosphate diphosphohydrolase 3	protein binding	Molecular function	25416956
MAD1L1	8379	MAD1 mitotic arrest deficient-like 1 (yeast)	mitotic cell cycle checkpoint	Biological process	9546394
CEP120	153241	centrosomal protein 120kDa	regulation of protein localization	Biological process	-
TAF7	6879	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa	protein binding	Molecular function	7824954
UBB	7314	ubiquitin B	error-free translesion synthesis	Biological process	-
SSR1	6745	signal sequence receptor, alpha	gene expression	Biological process	-
NKX3-2	579	NK3 homeobox 2	pancreas development	Biological process	-
MED7	9443	mediator complex subunit 7	nucleus	Cellular component	-
ODC1	4953	ornithine decarboxylase 1	response to virus	Biological process	16548883
OPN4	94233	opsin 4	visual perception	Biological process	-
GMEB2	26205	glucocorticoid modulatory element binding protein 2	transcription coactivator activity	Molecular function	-
SOCS4	122809	suppressor of cytokine signaling 4	cytokine-mediated signaling pathway	Biological process	-
TEK	7010	TEK tyrosine kinase, endothelial	positive regulation of endothelial cell proliferation	Biological process	18425120
DNASE1L2	1775	deoxyribonuclease I-like 2	calcium ion binding	Molecular function	9205125
DSCAML1	57453	Down syndrome cell adhesion molecule like 1	dendrite self-avoidance	Biological process	-
INSL4	3641	insulin-like 4 (placenta)	hormone activity	Molecular function	-
PFDN1	5201	prefoldin subunit 1	telencephalon development	Biological process	-
OR10R2	343406	olfactory receptor, family 10, subfamily R, member 2	G-protein coupled receptor signaling pathway	Biological process	-
NDUFA4	4697	NDUFA4, mitochondrial complex associated	cytochrome-c oxidase activity	Molecular function	22902835
SIRT5	23408	sirtuin 5	mitochondrial intermembrane space	Cellular component	18680753
EZH2	2146	enhancer of zeste 2 polycomb repressive complex 2 subunit	regulation of transcription, DNA-templated	Biological process	8921387
AGO2	27161	argonaute RISC catalytic component 2	mRNA cap binding complex	Cellular component	17524464
CER1	9350	cerberus 1, DAN family BMP antagonist	negative regulation of activin receptor signaling pathway	Biological process	-
MBTPS2	51360	membrane-bound transcription factor peptidase, site 2	metalloendopeptidase activity	Molecular function	-
BEST1	7439	bestrophin 1	chloride channel activity	Molecular function	17003041
SFRP1	6422	secreted frizzled-related protein 1	extracellular region	Cellular component	-
TDRD9	122402	tudor domain containing 9	ATP binding	Molecular function	-
ORAI2	80228	ORAI calcium release-activated calcium modulator 2	growth cone	Cellular component	-
PEX11G	92960	peroxisomal biogenesis factor 11 gamma	regulation of peroxisome size	Biological process	20826455
FRS2	10818	fibroblast growth factor receptor substrate 2	membrane	Cellular component	9660748
RMDN1	51115	regulator of microtubule dynamics 1	centrosome	Cellular component	-
IGHV4OR15-8	28317	immunoglobulin heavy variable 4/OR15-8 (non-functional)	extracellular region	Cellular component	-
NGF	4803	nerve growth factor (beta polypeptide)	nerve growth factor receptor binding	Molecular function	14985763
AUH	549	AU RNA binding protein/enoyl-CoA hydratase	mitochondrial matrix	Cellular component	-
SLC22A18	5002	solute carrier family 22, member 18	ubiquitin protein ligase binding	Molecular function	16314844
P2RX5	5026	purinergic receptor P2X, ligand gated ion channel, 5	integral component of nuclear inner membrane	Cellular component	-
MRPL13	28998	mitochondrial ribosomal protein L13	mitochondrial ribosome	Cellular component	20601428
WWTR1	25937	WW domain containing transcription regulator 1	negative regulation of catenin import into nucleus	Biological process	20412773
FIS1	51024	fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)	integral component of peroxisomal membrane	Cellular component	16107562
AGRN	375790	agrin	phototransduction, visible light	Biological process	-
GNB1	2782	guanine nucleotide binding protein (G protein), beta polypeptide 1	signal transduction	Biological process	7649993
TUBG2	27175	tubulin, gamma 2	GTP binding	Molecular function	-
CECR2	27443	cat eye syndrome chromosome region, candidate 2	cochlea development	Biological process	-
CACNA1B	774	calcium channel, voltage-dependent, N type, alpha 1B subunit	plasma membrane	Cellular component	-
TAF1	6872	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa	cellular response to DNA damage stimulus	Biological process	15053879
STXBP1	6812	syntaxin binding protein 1	cytosol	Cellular component	-
ACTN2	88	actinin, alpha 2	calcium ion binding	Molecular function	-
NR3C1	2908	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	16728402
UGT1A4	54657	UDP glucuronosyltransferase 1 family, polypeptide A4	retinoic acid binding	Molecular function	20308471
CHMP2B	25978	charged multivesicular body protein 2B	plasma membrane	Cellular component	24878737
CHMP5	51510	charged multivesicular body protein 5	protein transport	Biological process	-
SRSF5	6430	serine/arginine-rich splicing factor 5	mRNA 3'-end processing	Biological process	-
WISP2	8839	WNT1 inducible signaling pathway protein 2	plasma membrane	Cellular component	-
SMARCB1	6598	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	XY body	Cellular component	-
DAPK1	1612	death-associated protein kinase 1	protein autophosphorylation	Biological process	16756490
CDK11A	728642	cyclin-dependent kinase 11A	protein phosphorylation	Biological process	12501247
ADCY5	111	adenylate cyclase 5	locomotory behavior	Biological process	-
ZNF688	146542	zinc finger protein 688	DNA binding	Molecular function	-
STMN4	81551	stathmin-like 4	regulation of cytoskeleton organization	Biological process	-
BAG6	7917	BCL2-associated athanogene 6	tail-anchored membrane protein insertion into ER membrane	Biological process	20676083
POLR2K	5440	polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa	gene expression	Biological process	-
NEIL2	252969	nei endonuclease VIII-like 2 (E. coli)	DNA-(apurinic or apyrimidinic site) lyase activity	Molecular function	-
HAND2	9464	heart and neural crest derivatives expressed 2	protein homodimerization activity	Molecular function	-
CCR6	1235	chemokine (C-C motif) receptor 6	innate immune response	Biological process	-
GART	2618	phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase	cerebellum development	Biological process	-
BFAR	51283	bifunctional apoptosis regulator	protein K48-linked ubiquitination	Biological process	21068390
KCNE2	9992	potassium channel, voltage gated subfamily E regulatory beta subunit 2	positive regulation of proteasomal protein catabolic process	Biological process	22180649
TPO	7173	thyroid peroxidase	hydrogen peroxide catabolic process	Biological process	-
DZIP1L	199221	DAZ interacting zinc finger protein 1-like	cilium assembly	Biological process	19852954
IL4	3565	interleukin 4	female pregnancy	Biological process	-
RBMY1F	159163	RNA binding motif protein, Y-linked, family 1, member F	RNA binding	Molecular function	8269511
KRTAP9-2	83899	keratin associated protein 9-2	keratin filament	Cellular component	-
SEC24B	10427	SEC24 family member B	auditory receptor cell stereocilium organization	Biological process	-
GJA1	2697	gap junction protein, alpha 1, 43kDa	epithelial cell maturation	Biological process	-
RRP12	23223	ribosomal RNA processing 12 homolog (S. cerevisiae)	nuclear membrane	Cellular component	-
UBLCP1	134510	ubiquitin-like domain containing CTD phosphatase 1	protein binding	Molecular function	16189514
WT1	7490	Wilms tumor 1	vasculogenesis	Biological process	-
CBX4	8535	chromobox homolog 4	negative regulation of transcription, DNA-templated	Biological process	18567530
NMRK2	27231	nicotinamide riboside kinase 2	protein binding	Molecular function	12809483
ITPKA	3706	inositol-trisphosphate 3-kinase A	dendritic spine	Cellular component	-
GOT2	2806	glutamic-oxaloacetic transaminase 2, mitochondrial	response to ethanol	Biological process	9537447
TRIM39	56658	tripartite motif containing 39	apoptotic process	Biological process	-
FFAR1	2864	free fatty acid receptor 1	guanyl-nucleotide exchange factor activity	Molecular function	-
JAG1	182	jagged 1	protein binding	Molecular function	23086448
PROK2	60675	prokineticin 2	inflammatory response	Biological process	11259612
PLAG1	5324	pleiomorphic adenoma gene 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	10646861
CDCA5	113130	cell division cycle associated 5	chromatin binding	Molecular function	15837422
PPP2R2D	55844	protein phosphatase 2, regulatory subunit B, delta	cell division	Biological process	-
MRPL38	64978	mitochondrial ribosomal protein L38	mitochondrial translation	Biological process	-
ZNF469	84627	zinc finger protein 469	nucleus	Cellular component	-
AP4B1	10717	adaptor-related protein complex 4, beta 1 subunit	endosome lumen	Cellular component	-
KCNJ10	3766	potassium channel, inwardly rectifying subfamily J, member 10	receptor binding	Molecular function	-
SPRR2E	6704	small proline-rich protein 2E	protein binding	Molecular function	9722562
UGT2B10	7365	UDP glucuronosyltransferase 2 family, polypeptide B10	endoplasmic reticulum membrane	Cellular component	-
UTY	7404	ubiquitously transcribed tetratricopeptide repeat containing, Y-linked	histone H3-K27 demethylation	Biological process	-
CLIC2	1193	chloride intracellular channel 2	transport	Biological process	9339381
ROBO3	64221	roundabout, axon guidance receptor, homolog 3 (Drosophila)	axon guidance	Biological process	-
AIFM1	9131	apoptosis-inducing factor, mitochondrion-associated, 1	mitochondrion	Cellular component	20833797
BLMH	642	bleomycin hydrolase	aminopeptidase activity	Molecular function	9546396
TUBGCP3	10426	tubulin, gamma complex associated protein 3	single fertilization	Biological process	9138452
PHF19	26147	PHD finger protein 19	transcription, DNA-templated	Biological process	-
SOX9	6662	SRY (sex determining region Y)-box 9	Sertoli cell development	Biological process	-
WAPAL	23063	wings apart-like homolog (Drosophila)	cytoplasm	Cellular component	17113138
SPAM1	6677	sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)	anchored component of membrane	Cellular component	-
MBIP	51562	MAP3K12 binding inhibitory protein 1	histone H3 acetylation	Biological process	18838386
ADAM32	203102	ADAM metallopeptidase domain 32	integral component of membrane	Cellular component	-
PDHB	5162	pyruvate dehydrogenase (lipoamide) beta	mitochondrial matrix	Cellular component	-
ADCY6	112	adenylate cyclase 6	transmembrane transport	Biological process	-
WASF2	10163	WAS protein family, member 2	actin filament-based movement	Biological process	-
POLA1	5422	polymerase (DNA directed), alpha 1, catalytic subunit	nucleus	Cellular component	16762037
VPS37B	79720	vacuolar protein sorting 37 homolog B (S. cerevisiae)	positive regulation of viral release from host cell	Biological process	15218037
CFI	3426	complement factor I	extracellular exosome	Cellular component	19056867
CCNH	902	cyclin H	regulation of cyclin-dependent protein serine/threonine kinase activity	Biological process	-
UGT2B7	7364	UDP glucuronosyltransferase 2 family, polypeptide B7	cellular glucuronidation	Biological process	17442341
CYTH4	27128	cytohesin 4	ARF guanyl-nucleotide exchange factor activity	Molecular function	10652308
TRIM28	10155	tripartite motif containing 28	negative regulation of transcription, DNA-templated	Biological process	9016654
CISD2	493856	CDGSH iron sulfur domain 2	membrane	Cellular component	19946888
LRIT1	26103	leucine-rich repeat, immunoglobulin-like and transmembrane domains 1	molecular_function	Molecular function	-
SERPINA1	5265	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1	platelet activation	Biological process	-
SNRPA	6626	small nuclear ribonucleoprotein polypeptide A	spliceosomal complex	Cellular component	9731529
GRIN1	2902	glutamate receptor, ionotropic, N-methyl D-aspartate 1	regulation of membrane potential	Biological process	17047094
BCO2	83875	beta-carotene oxygenase 2	retinoic acid metabolic process	Biological process	11278918
RBP7	116362	retinol binding protein 7, cellular	cytoplasm	Cellular component	-
JMJD6	23210	jumonji domain containing 6	peptidyl-lysine 5-dioxygenase activity	Molecular function	19574390
ARRB2	409	arrestin, beta 2	alpha-1A adrenergic receptor binding	Molecular function	-
SLC35G2	80723	solute carrier family 35, member G2	integral component of plasma membrane	Cellular component	19148500
RAB11FIP4	84440	RAB11 family interacting protein 4 (class II)	protein binding	Molecular function	12470645
TNFRSF10D	8793	tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain	signal transduction	Biological process	9430226
CHST9	83539	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9	integral component of membrane	Cellular component	11139592
ST8SIA1	6489	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1	integral component of membrane	Cellular component	8195250
VPS36	51028	vacuolar protein sorting 36 homolog (S. cerevisiae)	regulation of transcription, DNA-templated	Biological process	-
MAD2L1BP	9587	MAD2L1 binding protein	spindle	Cellular component	-
RARB	5915	retinoic acid receptor, beta	steroid hormone receptor activity	Molecular function	-
ROR2	4920	receptor tyrosine kinase-like orphan receptor 2	transmembrane receptor protein tyrosine kinase signaling pathway	Biological process	-
SOCS5	9655	suppressor of cytokine signaling 5	protein binding	Molecular function	15590694
PSME3	10197	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)	antigen processing and presentation of exogenous peptide antigen via MHC class I	Biological process	-
ECEL1	9427	endothelin converting enzyme-like 1	respiratory system process	Biological process	-
YY1	7528	YY1 transcription factor	regulation of transcription from RNA polymerase II promoter	Biological process	1655281
HAS2	3037	hyaluronan synthase 2	positive regulation of cell migration	Biological process	22016393
ITPR3	3710	inositol 1,4,5-trisphosphate receptor, type 3	response to calcium ion	Biological process	19052258
HTT	3064	huntingtin	retrograde vesicle-mediated transport, Golgi to ER	Biological process	20515468
ALS2CL	259173	ALS2 C-terminal like	protein localization	Biological process	-
RHAG	6005	Rh-associated glycoprotein	carbon dioxide transport	Biological process	16574458
BUB1	699	BUB1 mitotic checkpoint serine/threonine kinase	regulation of chromosome segregation	Biological process	19487456
GRIK4	2900	glutamate receptor, ionotropic, kainate 4	presynaptic membrane	Cellular component	-
EIF2A	83939	eukaryotic translation initiation factor 2A, 65kDa	SREBP signaling pathway	Biological process	-
LRRC16A	55604	leucine rich repeat containing 16A	cell migration	Biological process	19846667
ZNF354C	30832	zinc finger protein 354C	metal ion binding	Molecular function	-
ZNF226	7769	zinc finger protein 226	sequence-specific DNA binding transcription factor activity	Molecular function	-
NOS1	4842	nitric oxide synthase 1 (neuronal)	cellular response to growth factor stimulus	Biological process	-
TJP1	7082	tight junction protein 1	plasma membrane	Cellular component	-
USP17L2	377630	ubiquitin specific peptidase 17-like family member 2	endoplasmic reticulum membrane	Cellular component	19188362
SHH	6469	sonic hedgehog	cerebellar granule cell precursor proliferation	Biological process	-
HLA-DRB3	3125	major histocompatibility complex, class II, DR beta 3	MHC class II protein complex	Cellular component	20356827
CCRN4L	25819	CCR4 carbon catabolite repression 4-like (S. cerevisiae)	response to lipopolysaccharide	Biological process	-
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	positive regulation of mesenchymal cell proliferation	Biological process	-
RHOXF1	158800	Rhox homeobox family, member 1	intracellular steroid hormone receptor signaling pathway	Biological process	11980563
INPP5K	51763	inositol polyphosphate-5-phosphatase K	positive regulation of renal water transport	Biological process	-
TP63	8626	tumor protein p63	sequence-specific DNA binding	Molecular function	-
CDC34	997	cell division cycle 34	positive regulation of neuron apoptotic process	Biological process	-
PRKCZ	5590	protein kinase C, zeta	perinuclear region of cytoplasm	Cellular component	-
VTN	7448	vitronectin	extracellular region	Cellular component	-
FLRT3	23767	fibronectin leucine rich transmembrane protein 3	receptor signaling protein activity	Molecular function	10644439
SNX13	23161	sorting nexin 13	intracellular protein transport	Biological process	11729322
SRI	6717	sorcin	protein binding	Molecular function	16189514
NOG	9241	noggin	lung morphogenesis	Biological process	-
FRS2	10818	fibroblast growth factor receptor substrate 2	anterior/posterior axis specification, embryo	Biological process	-
SERPINF2	5345	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2	negative regulation of plasminogen activation	Biological process	134998
MAPK8	5599	mitogen-activated protein kinase 8	JUN kinase activity	Molecular function	21095239
GNB1	2782	guanine nucleotide binding protein (G protein), beta polypeptide 1	small molecule metabolic process	Biological process	-
LSM4	25804	LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)	U6 snRNP	Cellular component	10369684
VAPA	9218	VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa	vesicle	Cellular component	10523508
KRT72	140807	keratin 72, type II	extracellular exosome	Cellular component	23533145
TNF	7124	tumor necrosis factor	negative regulation of alkaline phosphatase activity	Biological process	-
ATP10B	23120	ATPase, class V, type 10B	cytoplasmic vesicle membrane	Cellular component	-
NSD1	64324	nuclear receptor binding SET domain protein 1	nucleolus	Cellular component	-
NFRKB	4798	nuclear factor related to kappaB binding protein	protease binding	Molecular function	18922472
AQP8	343	aquaporin 8	cellular water homeostasis	Biological process	-
RARG	5916	retinoic acid receptor, gamma	sequence-specific DNA binding transcription factor activity	Molecular function	-
L1CAM	3897	L1 cell adhesion molecule	plasma membrane	Cellular component	-
HNRNPU	3192	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	RNA processing	Biological process	1628625
PAX6	5080	paired box 6	signal transduction involved in regulation of gene expression	Biological process	-
WNT11	7481	wingless-type MMTV integration site family, member 11	palate development	Biological process	18413325
IFNW1	3467	interferon, omega 1	cytokine-mediated signaling pathway	Biological process	-
SCAND1	51282	SCAN domain containing 1	sequence-specific DNA binding RNA polymerase II transcription factor activity	Molecular function	-
CCL11	6356	chemokine (C-C motif) ligand 11	protein phosphorylation	Biological process	10706854
ADRA1B	147	adrenoceptor alpha 1B	positive regulation of smooth muscle contraction	Biological process	-
MRPL49	740	mitochondrial ribosomal protein L49	protein binding	Molecular function	20601428
GEMIN4	50628	gem (nuclear organelle) associated protein 4	Gemini of coiled bodies	Cellular component	-
WNT5B	81029	wingless-type MMTV integration site family, member 5B	wound healing	Biological process	-
SLC6A4	6532	solute carrier family 6 (neurotransmitter transporter), member 4	membrane raft	Cellular component	16870614
PON2	5445	paraoxonase 2	plasma membrane	Cellular component	15772423
HERC1	8925	HECT and RLD domain containing E3 ubiquitin protein ligase family member 1	membrane	Cellular component	-
RPL9	6133	ribosomal protein L9	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Biological process	-
PTPRB	5787	protein tyrosine phosphatase, receptor type, B	phosphate-containing compound metabolic process	Biological process	2170109
MEX3B	84206	mex-3 RNA binding family member B	nucleoplasm	Cellular component	-
OR1Q1	158131	olfactory receptor, family 1, subfamily Q, member 1	sensory perception of smell	Biological process	9119360
PAX6	5080	paired box 6	retina development in camera-type eye	Biological process	-
PSMD2	5708	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition	Biological process	-
SERTAD1	29950	SERTA domain containing 1	transcription, DNA-templated	Biological process	-
GBA	2629	glucosidase, beta, acid	sphingolipid metabolic process	Biological process	-
AMFR	267	autocrine motility factor receptor, E3 ubiquitin protein ligase	protein oligomerization	Biological process	17310145
PDE9A	5152	phosphodiesterase 9A	cGMP-mediated signaling	Biological process	-
MOCOS	55034	molybdenum cofactor sulfurase	Mo-molybdopterin cofactor biosynthetic process	Biological process	-
C2CD2L	9854	C2CD2-like	insulin binding	Molecular function	-
PPP3R1	5534	protein phosphatase 3, regulatory subunit B, alpha	positive regulation of transcription from RNA polymerase II promoter	Biological process	22688515
PPAP2B	8613	phosphatidic acid phosphatase type 2B	phosphatidate phosphatase activity	Molecular function	-
IGF1R	3480	insulin-like growth factor 1 receptor	positive regulation of mitotic nuclear division	Biological process	-
EEF2K	29904	eukaryotic elongation factor 2 kinase	regulation of protein autophosphorylation	Biological process	-
CALM3	808	calmodulin 3 (phosphorylase kinase, delta)	phototransduction, visible light	Biological process	-
RBMY1B	378948	RNA binding motif protein, Y-linked, family 1, member B	RNA splicing	Biological process	10749975
DPP4	1803	dipeptidyl-peptidase 4	receptor binding	Molecular function	10900005
AQP3	360	aquaporin 3 (Gill blood group)	renal water homeostasis	Biological process	-
POP4	10775	processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)	tRNA processing	Biological process	-
VDR	7421	vitamin D (1,25- dihydroxyvitamin D3) receptor	bile acid signaling pathway	Biological process	12016314
CHD1L	9557	chromodomain helicase DNA binding protein 1-like	DNA repair	Biological process	19661379
NELL2	4753	NEL-like 2 (chicken)	cell	Cellular component	-
GCH1	2643	GTP cyclohydrolase 1	response to lipopolysaccharide	Biological process	15604419
SCGB2A2	4250	secretoglobin, family 2A, member 2	protein binding	Molecular function	25416956
TJP3	27134	tight junction protein 3	regulation of G1/S transition of mitotic cell cycle	Biological process	-
ACADVL	37	acyl-CoA dehydrogenase, very long chain	energy derivation by oxidation of organic compounds	Biological process	7479827
PDE6B	5158	phosphodiesterase 6B, cGMP-specific, rod, beta	phototransduction, visible light	Biological process	-
AGBL5	60509	ATP/GTP binding protein-like 5	proteolysis	Biological process	-
MYH14	79784	myosin, heavy chain 14, non-muscle	calmodulin binding	Molecular function	-
CYP7B1	9420	cytochrome P450, family 7, subfamily B, polypeptide 1	endoplasmic reticulum membrane	Cellular component	-
HRH3	11255	histamine receptor H3	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	Biological process	10347254
ARRB1	408	arrestin, beta 1	cytosol	Cellular component	-
RPL30	6156	ribosomal protein L30	cytosolic large ribosomal subunit	Cellular component	1577483
CX3CR1	1524	chemokine (C-X3-C motif) receptor 1	microglial cell activation involved in immune response	Biological process	-
COPE	11316	coatomer protein complex, subunit epsilon	membrane organization	Biological process	-
SNX6	58533	sorting nexin 6	vesicle organization	Biological process	-
EVI5L	115704	ecotropic viral integration site 5-like	positive regulation of GTPase activity	Biological process	-
CRP	1401	C-reactive protein, pentraxin-related	positive regulation of dendrite development	Biological process	-
TTPA	7274	tocopherol (alpha) transfer protein	phosphatidylinositol-4,5-bisphosphate binding	Molecular function	-
TRIM37	4591	tripartite motif containing 37	ligase activity	Molecular function	-
LIG1	3978	ligase I, DNA, ATP-dependent	telomere maintenance via recombination	Biological process	-
MED10	84246	mediator complex subunit 10	gene expression	Biological process	-
AGO2	27161	argonaute RISC catalytic component 2	miRNA loading onto RISC involved in gene silencing by miRNA	Biological process	18178619
IKBKG	8517	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	toll-like receptor 9 signaling pathway	Biological process	-
HPX	3263	hemopexin	heme transport	Biological process	3855550
BAD	572	BCL2-associated agonist of cell death	mitochondrion	Cellular component	-
DNAJC13	23317	DnaJ (Hsp40) homolog, subfamily C, member 13	endosome membrane	Cellular component	24643499
SNAP29	9342	synaptosomal-associated protein, 29kDa	synapse	Cellular component	-
OPN1SW	611	opsin 1 (cone pigments), short-wave-sensitive	phototransduction, visible light	Biological process	-
RAB3GAP2	25782	RAB3 GTPase activating protein subunit 2 (non-catalytic)	establishment of protein localization to endoplasmic reticulum membrane	Biological process	24891604
POLA1	5422	polymerase (DNA directed), alpha 1, catalytic subunit	DNA strand elongation involved in DNA replication	Biological process	-
TAF12	6883	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa	DNA binding	Molecular function	15601843
FAM175A	84142	family with sequence similarity 175, member A	positive regulation of DNA repair	Biological process	17525340
CRHR1	1394	corticotropin releasing hormone receptor 1	memory	Biological process	-
ANO6	196527	anoctamin 6	positive regulation of endothelial cell apoptotic process	Biological process	22006324
BBC3	27113	BCL2 binding component 3	positive regulation of intrinsic apoptotic signaling pathway	Biological process	-
FURIN	5045	furin (paired basic amino acid cleaving enzyme)	signal peptide processing	Biological process	16912035
CHL1	10752	cell adhesion molecule L1-like	proteinaceous extracellular matrix	Cellular component	-
ABI1	10006	abl-interactor 1	extracellular exosome	Cellular component	19056867
PSMB3	5691	proteasome (prosome, macropain) subunit, beta type, 3	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	Biological process	-
OR2A4	79541	olfactory receptor, family 2, subfamily A, member 4	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
ASCL1	429	achaete-scute family bHLH transcription factor 1	response to retinoic acid	Biological process	12000752
KIF12	113220	kinesin family member 12	kinesin complex	Cellular component	-
FKBP8	23770	FK506 binding protein 8, 38kDa	integral component of endoplasmic reticulum membrane	Cellular component	-
YIPF5	81555	Yip1 domain family, member 5	Golgi cisterna membrane	Cellular component	-
KIF27	55582	kinesin family member 27	cilium	Cellular component	-
NDUFS4	4724	NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)	mitochondrial electron transport, NADH to ubiquinone	Biological process	9463323
VPS4B	9525	vacuolar protein sorting 4 homolog B (S. cerevisiae)	endosome organization	Biological process	-
LPP	4026	LIM domain containing preferred translocation partner in lipoma	cell adhesion	Biological process	-
IDO1	3620	indoleamine 2,3-dioxygenase 1	female pregnancy	Biological process	9712583
ANTXR2	118429	anthrax toxin receptor 2	metal ion binding	Molecular function	-
PPP1R9B	84687	protein phosphatase 1, regulatory subunit 9B	cell cycle arrest	Biological process	11278317
AGL	178	amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase	cytosol	Cellular component	-
OR1G1	8390	olfactory receptor, family 1, subfamily G, member 1	olfactory receptor activity	Molecular function	-
INHA	3623	inhibin, alpha	negative regulation of follicle-stimulating hormone secretion	Biological process	3267209
LONP2	83752	lon peptidase 2, peroxisomal	peptidase activity	Molecular function	18281296
RAD23A	5886	RAD23 homolog A (S. cerevisiae)	polyubiquitin binding	Molecular function	12643283
HIST2H2AC	8338	histone cluster 2, H2ac	molecular_function	Molecular function	-
NCKAP1L	3071	NCK-associated protein 1-like	myeloid cell homeostasis	Biological process	-
EDIL3	10085	EGF-like repeats and discoidin I-like domains 3	integrin binding	Molecular function	-
CLP1	10978	cleavage and polyadenylation factor I subunit 1	tRNA splicing, via endonucleolytic cleavage and ligation	Biological process	24766809
UGT1A9	54600	UDP glucuronosyltransferase 1 family, polypeptide A9	glucuronosyltransferase activity	Molecular function	20610558
SUPT6H	6830	suppressor of Ty 6 homolog (S. cerevisiae)	regulation of isotype switching	Biological process	-
RAG1	5896	recombination activating gene 1	zinc ion binding	Molecular function	-
CEBPG	1054	CCAAT/enhancer binding protein (C/EBP), gamma	positive regulation of DNA repair	Biological process	16255782
ANG	283	angiogenin, ribonuclease, RNase A family, 5	rRNA transcription	Biological process	15735021
SEC62	7095	SEC62 homolog (S. cerevisiae)	protein transporter activity	Molecular function	-
ADGRL3	23284	adhesion G protein-coupled receptor L3	G-protein coupled receptor activity	Molecular function	10994649
E2F7	144455	E2F transcription factor 7	transcription factor complex	Cellular component	-
VIL1	7429	villin 1	actin nucleation	Biological process	-
CENPA	1058	centromere protein A	mitotic cell cycle	Biological process	-
PER1	5187	period circadian clock 1	regulation of p38MAPK cascade	Biological process	-
TIRAP	114609	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	I-kappaB kinase/NF-kappaB signaling	Biological process	-
BAG6	7917	BCL2-associated athanogene 6	ribosome binding	Molecular function	20676083
AGTR2	186	angiotensin II receptor, type 2	positive regulation of vasodilation	Biological process	15117835
KDELR1	10945	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1	endoplasmic reticulum membrane	Cellular component	-
NRL	4901	neural retina leucine zipper	nucleus	Cellular component	-
NCOR2	9612	nuclear receptor corepressor 2	transcription initiation from RNA polymerase II promoter	Biological process	-
PDGFC	56034	platelet derived growth factor C	cell surface	Cellular component	10806482
CEP192	55125	centrosomal protein 192kDa	mitotic cell cycle	Biological process	-
CAMLG	819	calcium modulating ligand	signal transduction	Biological process	7522304
LIF	3976	leukemia inhibitory factor	stem cell maintenance	Biological process	-
ACOT13	55856	acyl-CoA thioesterase 13	metabolic process	Biological process	-
CDC6	990	cell division cycle 6	G1/S transition of mitotic cell cycle	Biological process	-
LAMA5	3911	laminin, alpha 5	branching involved in ureteric bud morphogenesis	Biological process	-
FGFR2	2263	fibroblast growth factor receptor 2	fibroblast growth factor receptor signaling pathway	Biological process	-
KIF4A	24137	kinesin family member 4A	cytoplasm	Cellular component	7929562
PARM1	25849	prostate androgen-regulated mucin-like protein 1	integral component of membrane	Cellular component	-
TP53	7157	tumor protein p53	transcription factor TFIID complex	Cellular component	15053879
CEBPA	1050	CCAAT/enhancer binding protein (C/EBP), alpha	cytokine-mediated signaling pathway	Biological process	15664994
CR1	1378	complement component (3b/4b) receptor 1 (Knops blood group)	cell surface	Cellular component	2972794
FNBP1L	54874	formin binding protein 1-like	extracellular exosome	Cellular component	23376485
MCF2L	23263	MCF.2 cell line derived transforming sequence-like	positive regulation of apoptotic process	Biological process	-
TLE1	7088	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	positive regulation of gene expression	Biological process	15006356
FLI1	2313	Fli-1 proto-oncogene, ETS transcription factor	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
MRPS18B	28973	mitochondrial ribosomal protein S18B	cell junction	Cellular component	-
SDCBP	6386	syndecan binding protein (syntenin)	positive regulation of JNK cascade	Biological process	18256285
TOPBP1	11073	topoisomerase (DNA) II binding protein 1	male germ cell nucleus	Cellular component	-
NLRP2	55655	NLR family, pyrin domain containing 2	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	15030775
PITPNM3	83394	PITPNM family member 3	intracellular	Cellular component	-
USP41	373856	ubiquitin specific peptidase 41	ubiquitin-specific protease activity	Molecular function	-
LPP	4026	LIM domain containing preferred translocation partner in lipoma	focal adhesion	Cellular component	-
PHGDH	26227	phosphoglycerate dehydrogenase	cellular nitrogen compound metabolic process	Biological process	-
CALM1	801	calmodulin 1 (phosphorylase kinase, delta)	vascular endothelial growth factor receptor signaling pathway	Biological process	-
IL17B	27190	interleukin 17B	cytokine activity	Molecular function	-
HIST1H3G	8355	histone cluster 1, H3g	DNA methylation on cytosine	Biological process	-
AXL	558	AXL receptor tyrosine kinase	organ regeneration	Biological process	-
MSX2	4488	msh homeobox 2	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
ITGB1BP1	9270	integrin beta 1 binding protein 1	biomineral tissue development	Biological process	-
ISOC2	79763	isochorismatase domain containing 2	metabolic process	Biological process	-
TGFBI	7045	transforming growth factor, beta-induced, 68kDa	extracellular space	Cellular component	19478074
CSPG4	1464	chondroitin sulfate proteoglycan 4	small molecule metabolic process	Biological process	-
SMAD4	4089	SMAD family member 4	neuron fate commitment	Biological process	-
GAK	2580	cyclin G associated kinase	protein binding	Molecular function	22645275
TNFRSF1B	7133	tumor necrosis factor receptor superfamily, member 1B	protein binding	Molecular function	10848577
ROCK2	9475	Rho-associated, coiled-coil containing protein kinase 2	regulation of cell adhesion	Biological process	12778124
RAB5A	5868	RAB5A, member RAS oncogene family	axon	Cellular component	-
GPM6A	2823	glycoprotein M6A	stem cell differentiation	Biological process	19298174
NEK6	10783	NIMA-related kinase 6	positive regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	12761501
DUSP26	78986	dual specificity phosphatase 26 (putative)	RNA polymerase II activating transcription factor binding	Molecular function	16581800
MRPL53	116540	mitochondrial ribosomal protein L53	organelle organization	Biological process	-
OR2F1	26211	olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)	integral component of membrane	Cellular component	-
EDN1	1906	endothelin 1	dorsal/ventral pattern formation	Biological process	-
MAP1LC3C	440738	microtubule-associated protein 1 light chain 3 gamma	extrinsic component of membrane	Cellular component	-
C1orf43	25912	chromosome 1 open reading frame 43	integral component of membrane	Cellular component	-
FECH	2235	ferrochelatase	very-low-density lipoprotein particle assembly	Biological process	-
SPTB	6710	spectrin, beta, erythrocytic	protein complex	Cellular component	16060676
SLC18A1	6570	solute carrier family 18 (vesicular monoamine transporter), member 1	neurotransmitter transport	Biological process	-
LYAR	55646	Ly1 antibody reactive	nucleolus	Cellular component	-
HACL1	26061	2-hydroxyacyl-CoA lyase 1	cofactor binding	Molecular function	15644336
SLC4A5	57835	solute carrier family 4 (sodium bicarbonate cotransporter), member 5	integral component of membrane	Cellular component	10978526
ORC6	23594	origin recognition complex, subunit 6	membrane	Cellular component	19946888
MEF2D	4209	myocyte enhancer factor 2D	intracellular membrane-bounded organelle	Cellular component	-
RAD21	5885	RAD21 homolog (S. pombe)	chromosome	Cellular component	-
CHAT	1103	choline O-acetyltransferase	adult walking behavior	Biological process	-
FAM151A	338094	family with sequence similarity 151, member A	membrane	Cellular component	12975309
NR2F6	2063	nuclear receptor subfamily 2, group F, member 6	sequence-specific DNA binding	Molecular function	10644740
HMGB1	3146	high mobility group box 1	apoptotic DNA fragmentation	Biological process	-
CD19	930	CD19 molecule	cellular defense response	Biological process	1373518
JAK1	3716	Janus kinase 1	regulation of type I interferon-mediated signaling pathway	Biological process	-
CSNK1G2	1455	casein kinase 1, gamma 2	glycoprotein binding	Molecular function	-
PEX14	5195	peroxisomal biogenesis factor 14	peroxisomal membrane	Cellular component	-
ERBB3	2065	erb-b2 receptor tyrosine kinase 3	ATP binding	Molecular function	-
CNTNAP2	26047	contactin associated protein-like 2	early endosome	Cellular component	19706678
EXTL2	2135	exostosin-like glycosyltransferase 2	glycosaminoglycan biosynthetic process	Biological process	-
SIX3	6496	SIX homeobox 3	regulation of cell cycle phase transition	Biological process	-
CAV2	858	caveolin 2	vesicle docking	Biological process	12743374
ADGRG7	84873	adhesion G protein-coupled receptor G7	plasma membrane	Cellular component	-
PANK3	79646	pantothenate kinase 3	ATP binding	Molecular function	-
RYR2	6262	ryanodine receptor 2 (cardiac)	cellular calcium ion homeostasis	Biological process	-
TBX18	9096	T-box 18	nucleus	Cellular component	-
PRKCH	5583	protein kinase C, eta	regulation of bicellular tight junction assembly	Biological process	19114660
ANKRD1	27063	ankyrin repeat domain 1 (cardiac muscle)	negative regulation of DNA biosynthetic process	Biological process	11139470
ROCK1	6093	Rho-associated, coiled-coil containing protein kinase 1	regulation of cell motility	Biological process	12778124
VEGFC	7424	vascular endothelial growth factor C	extracellular region	Cellular component	-
ATPIF1	93974	ATPase inhibitory factor 1	mitochondrial proton-transporting ATP synthase complex	Cellular component	12110673
RAPGEF1	2889	Rap guanine nucleotide exchange factor (GEF) 1	transmembrane receptor protein tyrosine kinase signaling pathway	Biological process	7512734
TTYH1	57348	tweety family member 1	iron ion transmembrane transporter activity	Molecular function	10950931
XPR1	9213	xenotropic and polytropic retrovirus receptor 1	integral component of plasma membrane	Cellular component	9927670
VPS37C	55048	vacuolar protein sorting 37 homolog C (S. cerevisiae)	endosome membrane	Cellular component	-
CDC5L	988	cell division cycle 5-like	signal transduction involved in DNA damage checkpoint	Biological process	24332808
FAS	355	Fas cell surface death receptor	signal transduction	Biological process	9360929
METTL21B	25895	methyltransferase like 21B	methyltransferase activity	Molecular function	-
OPTN	10133	optineurin	nucleus	Cellular component	-
RAB1A	5861	RAB1A, member RAS oncogene family	defense response to bacterium	Biological process	22939626
SKI	6497	SKI proto-oncogene	chromatin binding	Molecular function	-
SLC39A1	27173	solute carrier family 39 (zinc transporter), member 1	cation transport	Biological process	10610721
KCND2	3751	potassium channel, voltage gated Shal related subfamily D, member 2	metal ion binding	Molecular function	-
TMEM101	84336	transmembrane protein 101	cellular_component	Cellular component	-
APOC3	345	apolipoprotein C-III	response to nutrient	Biological process	-
CLIC1	1192	chloride intracellular channel 1	extracellular exosome	Cellular component	15326289
HEPACAM2	253012	HEPACAM family member 2	protein binding	Molecular function	22864114
IPPK	64768	inositol 1,3,4,5,6-pentakisphosphate 2-kinase	ATP binding	Molecular function	-
FAM96A	84191	family with sequence similarity 96, member A	cellular_component	Cellular component	-
TTLL12	23170	tubulin tyrosine ligase-like family member 12	cellular protein modification process	Biological process	-
CTNNA2	1496	catenin (cadherin-associated protein), alpha 2	adherens junction	Cellular component	-
NANP	140838	N-acetylneuraminic acid phosphatase	dephosphorylation	Biological process	-
GNLY	10578	granulysin	killing of cells of other organism	Biological process	-
PGM2L1	283209	phosphoglucomutase 2-like 1	galactose catabolic process	Biological process	-
R3HCC1	203069	R3H domain and coiled-coil containing 1	exon-exon junction complex	Cellular component	-
WNT10A	80326	wingless-type MMTV integration site family, member 10A	extracellular region	Cellular component	-
EPO	2056	erythropoietin	regulation of transcription from RNA polymerase II promoter in response to hypoxia	Biological process	-
PRKAG2	51422	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	nucleoplasm	Cellular component	-
ZDHHC21	340481	zinc finger, DHHC-type containing 21	Golgi apparatus	Cellular component	22031296
JMJD1C	221037	jumonji domain containing 1C	thyroid hormone receptor binding	Molecular function	7776974
WDR1	9948	WD repeat domain 1	extracellular exosome	Cellular component	19056867
COG2	22796	component of oligomeric golgi complex 2	Golgi organization	Biological process	7962052
STXBP1	6812	syntaxin binding protein 1	platelet degranulation	Biological process	12773094
NUP214	8021	nucleoporin 214kDa	nucleus	Cellular component	-
HFE	3077	hemochromatosis	apical part of cell	Cellular component	15880641
GJA1	2697	gap junction protein, alpha 1, 43kDa	contractile fiber	Cellular component	-
APOE	348	apolipoprotein E	cholesterol metabolic process	Biological process	3771793
TTLL4	9654	tubulin tyrosine ligase-like family member 4	cytoskeleton	Cellular component	-
CCNE1	898	cyclin E1	androgen receptor binding	Molecular function	15572661
TSGA10	80705	testis specific, 10	spermatogenesis	Biological process	11179690
VAV2	7410	vav 2 guanine nucleotide exchange factor	lamellipodium assembly	Biological process	-
SENP1	29843	SUMO1/sentrin specific peptidase 1	SUMO-specific protease activity	Molecular function	-
POPDC2	64091	popeye domain containing 2	cAMP binding	Molecular function	-
PARP14	54625	poly (ADP-ribose) polymerase family, member 14	cytoplasm	Cellular component	-
SLC22A6	9356	solute carrier family 22 (organic anion transporter), member 6	protein complex	Cellular component	-
CRY1	1407	cryptochrome circadian clock 1	gluconeogenesis	Biological process	-
PDGFRB	5159	platelet-derived growth factor receptor, beta polypeptide	response to hydrogen peroxide	Biological process	-
SRRM4	84530	serine/arginine repetitive matrix 4	mRNA processing	Biological process	-
KCNS2	3788	potassium voltage-gated channel, modifier subfamily S, member 2	voltage-gated potassium channel complex	Cellular component	-
DXO	1797	decapping exoribonuclease	RNA pyrophosphohydrolase activity	Molecular function	-
HMGB2	3148	high mobility group box 2	cellular response to lipopolysaccharide	Biological process	19811285
COX5A	9377	cytochrome c oxidase subunit Va	metal ion binding	Molecular function	-
DMRTC2	63946	DMRT-like family C2	positive regulation of histone H3-K9 trimethylation	Biological process	-
PSMB1	5689	proteasome (prosome, macropain) subunit, beta type, 1	cytoplasm	Cellular component	-
RANGRF	29098	RAN guanine nucleotide release factor	cytoplasm	Cellular component	-
TNFRSF1A	7132	tumor necrosis factor receptor superfamily, member 1A	cellular response to estradiol stimulus	Biological process	-
GNAQ	2776	guanine nucleotide binding protein (G protein), q polypeptide	metabolic process	Biological process	9238049
UGT1A6	54578	UDP glucuronosyltransferase 1 family, polypeptide A6	retinoic acid binding	Molecular function	20308471
NDC80	10403	NDC80 kinetochore complex component	condensed chromosome kinetochore	Cellular component	14699129
CD8A	925	CD8a molecule	protein binding	Molecular function	2470098
BLOC1S1	2647	biogenesis of lysosomal organelles complex-1, subunit 1	mitochondrial matrix	Cellular component	22309213
KCNC3	3748	potassium channel, voltage gated Shaw related subfamily C, member 3	voltage-gated potassium channel complex	Cellular component	-
RELA	5970	v-rel avian reticuloendotheliosis viral oncogene homolog A	DNA binding	Molecular function	18212740
TBX1	6899	T-box 1	inner ear morphogenesis	Biological process	-
TIA1	7072	TIA1 cytotoxic granule-associated RNA binding protein	nucleotide binding	Molecular function	-
FGF12	2257	fibroblast growth factor 12	positive regulation of sodium ion transport	Biological process	-
HOXB9	3219	homeobox B9	cell chemotaxis	Biological process	19576624
CTPS1	1503	CTP synthase 1	CTP synthase activity	Molecular function	24870241
CNIH3	149111	cornichon family AMPA receptor auxiliary protein 3	intracellular	Cellular component	-
CLN3	1201	ceroid-lipofuscinosis, neuronal 3	galactosylceramide metabolic process	Biological process	15240864
CACNA1F	778	calcium channel, voltage-dependent, L type, alpha 1F subunit	dendrite morphogenesis	Biological process	-
PIK3R1	5295	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	cellular glucose homeostasis	Biological process	-
ENPP3	5169	ectonucleotide pyrophosphatase/phosphodiesterase 3	metal ion binding	Molecular function	-
UBE2D1	7321	ubiquitin-conjugating enzyme E2D 1	protein K48-linked ubiquitination	Biological process	20061386
RAG1	5896	recombination activating gene 1	ubiquitin-protein transferase activity	Molecular function	-
PSMD5	5711	proteasome (prosome, macropain) 26S subunit, non-ATPase, 5	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	Biological process	-
FOSL1	8061	FOS-like antigen 1	positive regulation of cell proliferation	Biological process	8230424
ACY1	95	aminoacylase 1	proteolysis	Biological process	-
ASMT	438	acetylserotonin O-methyltransferase	O-methyltransferase activity	Molecular function	8397829
ATP8A2	51761	ATPase, aminophospholipid transporter, class I, type 8A, member 2	positive regulation of phospholipid translocation	Biological process	-
CALML5	51806	calmodulin-like 5	epidermis development	Biological process	10777582
FXYD7	53822	FXYD domain containing ion transport regulator 7	protein binding	Molecular function	25416956
SNX6	58533	sorting nexin 6	dynactin binding	Molecular function	19619496
ARFGEF2	10564	ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)	perinuclear region of cytoplasm	Cellular component	-
OR51G2	81282	olfactory receptor, family 51, subfamily G, member 2	G-protein coupled receptor activity	Molecular function	-
CENPA	1058	centromere protein A	nucleoplasm	Cellular component	-
AMDHD2	51005	amidohydrolase domain containing 2	nucleus	Cellular component	21630459
PSMD11	5717	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	proteasome accessory complex	Cellular component	22972301
TAC1	6863	tachykinin, precursor 1	protein binding	Molecular function	23597562
LIN9	286826	lin-9 DREAM MuvB core complex component	DNA biosynthetic process	Biological process	-
PLB1	151056	phospholipase B1	lysophospholipase activity	Molecular function	-
RIC8A	60626	RIC8 guanine nucleotide exchange factor A	positive regulation of GTPase activity	Biological process	-
GATA1	2623	GATA binding protein 1 (globin transcription factor 1)	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
ADORA2A	135	adenosine A2a receptor	positive regulation of circadian sleep/wake cycle, sleep	Biological process	-
ZNF346	23567	zinc finger protein 346	protein binding	Molecular function	21903422
TEX14	56155	testis expressed 14	protein phosphorylation	Biological process	-
TAB1	10454	TGF-beta activated kinase 1/MAP3K7 binding protein 1	protein complex	Cellular component	-
GSTP1	2950	glutathione S-transferase pi 1	cytosol	Cellular component	-
MAPK8	5599	mitogen-activated protein kinase 8	JUN phosphorylation	Biological process	14967141
ZNF747	65988	zinc finger protein 747	nucleic acid binding	Molecular function	-
OR6P1	128366	olfactory receptor, family 6, subfamily P, member 1	G-protein coupled receptor signaling pathway	Biological process	-
STAT5A	6776	signal transducer and activator of transcription 5A	lipid storage	Biological process	-
ID2	3398	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	chromatin	Cellular component	-
GABRG3	2567	gamma-aminobutyric acid (GABA) A receptor, gamma 3	chloride channel activity	Molecular function	-
EIF3A	8661	eukaryotic translation initiation factor 3, subunit A	formation of translation preinitiation complex	Biological process	-
VGF	7425	VGF nerve growth factor inducible	sexual reproduction	Biological process	-
CFL1	1072	cofilin 1 (non-muscle)	cortical actin cytoskeleton	Cellular component	-
SLC22A15	55356	solute carrier family 22, member 15	transmembrane transporter activity	Molecular function	-
PSMD14	10213	proteasome (prosome, macropain) 26S subunit, non-ATPase, 14	double-strand break repair via nonhomologous end joining	Biological process	22909820
AGPAT6	137964	1-acylglycerol-3-phosphate O-acyltransferase 6	triglyceride biosynthetic process	Biological process	-
PCED1A	64773	PC-esterase domain containing 1A	protein binding	Molecular function	25416956
TGFB1	7040	transforming growth factor, beta 1	epithelial to mesenchymal transition	Biological process	-
GDPD1	284161	glycerophosphodiester phosphodiesterase domain containing 1	integral component of membrane	Cellular component	-
ITGB4	3691	integrin, beta 4	response to wounding	Biological process	19403692
PSMD7	5713	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	gene expression	Biological process	-
DEFB126	81623	defensin, beta 126	cell surface	Cellular component	-
UMOD	7369	uromodulin	cellular defense response	Biological process	2409603
GNB2L1	10399	guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1	nucleus	Cellular component	10849009
P2RY1	5028	purinergic receptor P2Y, G-protein coupled, 1	protein binding	Molecular function	9671706
ERCC4	2072	excision repair cross-complementation group 4	nucleotide-excision repair complex	Cellular component	10644440
GLI3	2737	GLI family zinc finger 3	embryonic digit morphogenesis	Biological process	11001584
BTK	695	Bruton agammaglobulinemia tyrosine kinase	cell maturation	Biological process	-
CHRNA3	1136	cholinergic receptor, nicotinic, alpha 3 (neuronal)	behavioral response to nicotine	Biological process	18227835
SRRM1	10250	serine/arginine repetitive matrix 1	catalytic step 2 spliceosome	Cellular component	11991638
MAP3K19	80122	mitogen-activated protein kinase kinase kinase 19	cytoplasm	Cellular component	-
HTR3B	9177	5-hydroxytryptamine (serotonin) receptor 3B, ionotropic	serotonin receptor signaling pathway	Biological process	-
AKR1E2	83592	aldo-keto reductase family 1, member E2	activation of mitophagy in response to mitochondrial depolarization	Biological process	22020285
ARF5	381	ADP-ribosylation factor 5	metabolic process	Biological process	1993656
TLR2	7097	toll-like receptor 2	signaling pattern recognition receptor activity	Molecular function	10384090
CREBZF	58487	CREB/ATF bZIP transcription factor	DNA binding	Molecular function	10871379
NEFL	4747	neurofilament, light polypeptide	intermediate filament organization	Biological process	12432080
PPFIA1	8500	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1	signal transduction	Biological process	7796809
LMO2	4005	LIM domain only 2 (rhombotin-like 1)	cellular response to thyroid hormone stimulus	Biological process	19375645
RNF7	9616	ring finger protein 7	Cul5-RING ubiquitin ligase complex	Cellular component	22405651
MRE11A	4361	MRE11 meiotic recombination 11 homolog A (S. cerevisiae)	synapsis	Biological process	-
LILRB3	11025	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	protein binding	Molecular function	18802077
C1QBP	708	complement component 1, q subcomponent binding protein	protein kinase C binding	Molecular function	-
RPL5	6125	ribosomal protein L5	cytosolic large ribosomal subunit	Cellular component	12962325
DCTN1	1639	dynactin 1	membrane	Cellular component	19946888
CBR4	84869	carbonyl reductase 4	mitochondrial matrix	Cellular component	-
NUPL2	11097	nucleoporin like 2	cellular protein metabolic process	Biological process	-
PMS2P3	5387	postmeiotic segregation increased 2 pseudogene 3	mismatch repair complex	Cellular component	-
PDE2A	5138	phosphodiesterase 2A, cGMP-stimulated	negative regulation of transcription from RNA polymerase II promoter	Biological process	17329248
SMEK2	57223	SMEK homolog 2, suppressor of mek1 (Dictyostelium)	microtubule organizing center	Cellular component	-
CLEC4D	338339	C-type lectin domain family 4, member D	carbohydrate binding	Molecular function	-
PARP16	54956	poly (ADP-ribose) polymerase family, member 16	endoplasmic reticulum tubular network	Cellular component	22701565
FNBP1L	54874	formin binding protein 1-like	membrane invagination	Biological process	20730103
POLE2	5427	polymerase (DNA directed), epsilon 2, accessory subunit	telomere maintenance via recombination	Biological process	-
CYP11A1	1583	cytochrome P450, family 11, subfamily A, polypeptide 1	response to vitamin E	Biological process	-
RANGAP1	5905	Ran GTPase activating protein 1	kinetochore	Cellular component	17363900
SOX8	30812	SRY (sex determining region Y)-box 8	positive regulation of transcription from RNA polymerase II promoter	Biological process	10662550
LRRC8B	23507	leucine rich repeat containing 8 family, member B	plasma membrane	Cellular component	-
ZFY	7544	zinc finger protein, Y-linked	transcription, DNA-templated	Biological process	-
KIF20A	10112	kinesin family member 20A	midbody	Cellular component	15843429
TAP1	6890	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	peptide transporter activity	Molecular function	17418234
ALDOC	230	aldolase C, fructose-bisphosphate	protein homotetramerization	Biological process	-
BMP6	654	bone morphogenetic protein 6	male genitalia development	Biological process	-
CCT3	7203	chaperonin containing TCP1, subunit 3 (gamma)	protein folding	Biological process	-
TXN	7295	thioredoxin	sulfate assimilation	Biological process	-
PARP16	54956	poly (ADP-ribose) polymerase family, member 16	protein binding	Molecular function	22701565
TMSB4X	7114	thymosin beta 4, X-linked	extracellular region	Cellular component	-
SLC35B4	84912	solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4	UDP-xylose transport	Biological process	15911612
MYO10	4651	myosin X	actin filament binding	Molecular function	-
PPIA	5478	peptidylprolyl isomerase A (cyclophilin A)	viral process	Biological process	-
HIST1H3B	8358	histone cluster 1, H3b	DNA methylation on cytosine	Biological process	-
ZNF549	256051	zinc finger protein 549	transcription, DNA-templated	Biological process	-
RHBDL2	54933	rhomboid, veinlet-like 2 (Drosophila)	protein processing	Biological process	-
SAFB	6294	scaffold attachment factor B	transcription, DNA-templated	Biological process	-
RWDD3	25950	RWD domain containing 3	negative regulation of NF-kappaB transcription factor activity	Biological process	23469069
JTB	10899	jumping translocation breakpoint	midbody	Cellular component	21225229
DYM	54808	dymeclin	Golgi organization	Biological process	21280149
ACSL6	23305	acyl-CoA synthetase long-chain family member 6	ATP binding	Molecular function	-
FZD10	11211	frizzled class receptor 10	cell surface	Cellular component	18271942
KCNE3	10008	potassium channel, voltage gated subfamily E regulatory beta subunit 3	cytoplasm	Cellular component	12954870
AQP9	366	aquaporin 9	intracellular membrane-bounded organelle	Cellular component	18718702
TMEM160	54958	transmembrane protein 160	integral component of membrane	Cellular component	-
TMEM92	162461	transmembrane protein 92	integral component of membrane	Cellular component	-
EPHA2	1969	EPH receptor A2	cell surface	Cellular component	19581412
BCR	613	breakpoint cluster region	platelet-derived growth factor receptor signaling pathway	Biological process	-
ITGB1BP1	9270	integrin beta 1 binding protein 1	negative regulation of protein targeting to membrane	Biological process	11807099
CDC42	998	cell division cycle 42	cellular protein localization	Biological process	-
B4GALT5	9334	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5	carbohydrate metabolic process	Biological process	-
TYR	7299	tyrosinase	protein heterodimerization activity	Molecular function	-
PARS2	25973	prolyl-tRNA synthetase 2, mitochondrial (putative)	gene expression	Biological process	-
PPP3CA	5530	protein phosphatase 3, catalytic subunit, alpha isozyme	G1/S transition of mitotic cell cycle	Biological process	-
GRID2	2895	glutamate receptor, ionotropic, delta 2	extracellular-glutamate-gated ion channel activity	Molecular function	-
TGFBR1	7046	transforming growth factor, beta receptor 1	positive regulation of cell growth	Biological process	18625725
ZNF100	163227	zinc finger protein 100	DNA binding	Molecular function	-
HEY1	23462	hes-related family bHLH transcription factor with YRPW motif 1	RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity	Molecular function	-
HTR7	3363	5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled	circadian rhythm	Biological process	-
HIST1H3F	8968	histone cluster 1, H3f	nucleus	Cellular component	21630459
NR2F6	2063	nuclear receptor subfamily 2, group F, member 6	thyroid hormone receptor activity	Molecular function	2905047
FUT5	2527	fucosyltransferase 5 (alpha (1,3) fucosyltransferase)	L-fucose catabolic process	Biological process	11698403
ZBTB33	10009	zinc finger and BTB domain containing 33	negative regulation of transcription, DNA-templated	Biological process	16354688
NPBWR2	2832	neuropeptides B/W receptor 2	synaptic transmission	Biological process	-
CDAN1	146059	codanin 1	chromatin assembly	Biological process	22407294
PPARG	5468	peroxisome proliferator-activated receptor gamma	response to low-density lipoprotein particle	Biological process	9568716
PTCH1	5727	patched 1	mammary gland epithelial cell differentiation	Biological process	-
RDH10	157506	retinol dehydrogenase 10 (all-trans)	retinoid metabolic process	Biological process	-
TTC17	55761	tetratricopeptide repeat domain 17	protein binding	Molecular function	24475127
FGB	2244	fibrinogen beta chain	plasma membrane	Cellular component	-
ZAP70	7535	zeta-chain (TCR) associated protein kinase 70kDa	cytosol	Cellular component	-
ZDHHC17	23390	zinc finger, DHHC-type containing 17	intracellular membrane-bounded organelle	Cellular component	-
Sep-05	5413	septin 5	structural molecule activity	Molecular function	9611266
CPS1	1373	carbamoyl-phosphate synthase 1, mitochondrial	response to toxic substance	Biological process	-
NOLC1	9221	nucleolar and coiled-body phosphoprotein 1	cell cycle	Biological process	7657714
TAB3	257397	TGF-beta activated kinase 1/MAP3K7 binding protein 3	extracellular exosome	Cellular component	18570454
PTEN	5728	phosphatase and tensin homolog	neurotrophin TRK receptor signaling pathway	Biological process	-
CAPRIN1	4076	cell cycle associated protein 1	cytoplasmic mRNA processing body	Cellular component	-
PANK4	55229	pantothenate kinase 4	pantothenate kinase activity	Molecular function	-
FERMT2	10979	fermitin family member 2	I band	Cellular component	-
CLN8	2055	ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)	endoplasmic reticulum membrane	Cellular component	-
RPS6KB1	6198	ribosomal protein S6 kinase, 70kDa, polypeptide 1	protein binding	Molecular function	11438723
CTNNA1	1495	catenin (cadherin-associated protein), alpha 1, 102kDa	cell-cell junction	Cellular component	10460003
KRTAP27-1	643812	keratin associated protein 27-1	intermediate filament	Cellular component	-
MOGS	7841	mannosyl-oligosaccharide glucosidase	extracellular exosome	Cellular component	19056867
RAB7B	338382	RAB7B, member RAS oncogene family	Golgi apparatus	Cellular component	20375062
OR2A4	79541	olfactory receptor, family 2, subfamily A, member 4	mitotic spindle pole	Cellular component	22888021
MC5R	4161	melanocortin 5 receptor	plasma membrane	Cellular component	-
PKN2	5586	protein kinase N2	positive regulation of cytokinesis	Biological process	17332740
XYLT2	64132	xylosyltransferase II	chondroitin sulfate biosynthetic process	Biological process	-
NCOA6	23054	nuclear receptor coactivator 6	estrogen receptor binding	Molecular function	11443112
AK3	50808	adenylate kinase 3	blood coagulation	Biological process	-
FGF9	2254	fibroblast growth factor 9	signal transduction	Biological process	8575785
XPA	7507	xeroderma pigmentosum, complementation group A	response to UV	Biological process	-
MTHFD1L	25902	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like	tetrahydrofolate metabolic process	Biological process	12937168
SUPT5H	6829	suppressor of Ty 5 homolog (S. cerevisiae)	negative regulation of DNA-templated transcription, elongation	Biological process	10075709
MAP1A	4130	microtubule-associated protein 1A	microtubule cytoskeleton organization	Biological process	-
VAC14	55697	Vac14 homolog (S. cerevisiae)	phosphatidylinositol biosynthetic process	Biological process	-
DTX2	113878	deltex 2, E3 ubiquitin ligase	nucleoplasm	Cellular component	-
ACTB	60	actin, beta	nuclear chromatin	Cellular component	16217013
CEP131	22994	centrosomal protein 131kDa	positive regulation of intracellular protein transport	Biological process	24550735
HBB	3043	hemoglobin, beta	positive regulation of cell death	Biological process	19740759
SGPL1	8879	sphingosine-1-phosphate lyase 1	fatty acid metabolic process	Biological process	24809814
SERPINA3	12	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3	acute-phase response	Biological process	-
RHOA	387	ras homolog family member A	mitotic spindle assembly	Biological process	19635168
BLOC1S1	2647	biogenesis of lysosomal organelles complex-1, subunit 1	lysosomal membrane	Cellular component	-
OR52K2	119774	olfactory receptor, family 52, subfamily K, member 2	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
SERP1	27230	stress-associated endoplasmic reticulum protein 1	IRE1-mediated unfolded protein response	Biological process	-
NUPR1	26471	nuclear protein, transcriptional regulator, 1	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	Biological process	-
RPGR	6103	retinitis pigmentosa GTPase regulator	eye photoreceptor cell development	Biological process	-
CD200	4345	CD200 molecule	regulation of immune response	Biological process	-
NCF4	4689	neutrophil cytosolic factor 4, 40kDa	vascular endothelial growth factor receptor signaling pathway	Biological process	-
CEBPB	1051	CCAAT/enhancer binding protein (C/EBP), beta	neuron differentiation	Biological process	-
TOP3B	8940	topoisomerase (DNA) III beta	DNA topoisomerase type I activity	Molecular function	-
RORA	6095	RAR-related orphan receptor A	muscle cell differentiation	Biological process	9862959
ATP6V1A	523	ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A	interaction with host	Biological process	-
DAG1	1605	dystroglycan 1 (dystrophin-associated glycoprotein 1)	cytoskeletal anchoring at plasma membrane	Biological process	18341635
BRD4	23476	bromodomain containing 4	cytoplasm	Cellular component	-
GADD45GIP1	90480	growth arrest and DNA-damage-inducible, gamma interacting protein 1	mitochondrial translational initiation	Biological process	-
CEP290	80184	centrosomal protein 290kDa	protein binding	Molecular function	16682973
SPATA16	83893	spermatogenesis associated 16	spermatogenesis	Biological process	-
TLR6	10333	toll-like receptor 6	regulation of cytokine secretion	Biological process	-
FREM2	341640	FRAS1 related extracellular matrix protein 2	homophilic cell adhesion via plasma membrane adhesion molecules	Biological process	-
ELP2	55250	elongator acetyltransferase complex subunit 2	histone acetyltransferase complex	Cellular component	11714725
ARHGAP17	55114	Rho GTPase activating protein 17	positive regulation of GTPase activity	Biological process	-
NINJ1	4814	ninjurin 1	protein binding	Molecular function	25416956
CNTNAP3	79937	contactin associated protein-like 3	cell adhesion	Biological process	-
MYH9	4627	myosin, heavy chain 9, non-muscle	plasma membrane	Cellular component	15064761
PAK2	5062	p21 protein (Cdc42/Rac)-activated kinase 2	plasma membrane	Cellular component	-
SHISA3	152573	shisa family member 3	integral component of membrane	Cellular component	-
OR10C1	442194	olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)	sensory perception of smell	Biological process	-
PPID	5481	peptidylprolyl isomerase D	positive regulation of apoptotic process	Biological process	23220213
HSPA8	3312	heat shock 70kDa protein 8	regulation of cellular response to heat	Biological process	-
SP3	6670	Sp3 transcription factor	embryonic skeletal system development	Biological process	-
CAMK2A	815	calcium/calmodulin-dependent protein kinase II alpha	protein autophosphorylation	Biological process	-
PMCH	5367	pro-melanin-concentrating hormone	neuropeptide signaling pathway	Biological process	-
PPP1R17	10842	protein phosphatase 1, regulatory subunit 17	intracellular	Cellular component	10051666
SELL	6402	selectin L	cell adhesion molecule binding	Molecular function	-
CAMK4	814	calcium/calmodulin-dependent protein kinase IV	calcium-dependent protein serine/threonine kinase activity	Molecular function	-
LRRC4	64101	leucine rich repeat containing 4	regulation of synapse organization	Biological process	-
CDKN1A	1026	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	fibroblast growth factor receptor signaling pathway	Biological process	-
EPS15	2060	epidermal growth factor receptor pathway substrate 15	polyubiquitin binding	Molecular function	24768539
NMUR2	56923	neuromedin U receptor 2	cytosol	Cellular component	10899166
MFSD10	10227	major facilitator superfamily domain containing 10	transport	Biological process	8353488
STUB1	10273	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase	protein homodimerization activity	Molecular function	-
PTMA	5757	prothymosin, alpha	cytoplasm	Cellular component	-
CTSS	1520	cathepsin S	endolysosome lumen	Cellular component	-
HLA-DRB1	3123	major histocompatibility complex, class II, DR beta 1	detection of bacterium	Biological process	-
ANKS6	203286	ankyrin repeat and sterile alpha motif domain containing 6	protein homodimerization activity	Molecular function	-
GALNT2	2590	polypeptide N-acetylgalactosaminyltransferase 2	protein O-linked glycosylation via threonine	Biological process	12438318
CD209	30835	CD209 molecule	carbohydrate binding	Molecular function	11337487
NUS1	116150	nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)	endoplasmic reticulum membrane	Cellular component	19723497
FRMD4A	55691	FERM domain containing 4A	establishment of epithelial cell polarity	Biological process	-
RPL35A	6165	ribosomal protein L35a	viral life cycle	Biological process	-
RTTN	25914	rotatin	cilium organization	Biological process	-
RNF139	11236	ring finger protein 139	protein binding	Molecular function	12032852
CLEC9A	283420	C-type lectin domain family 9, member A	carbohydrate binding	Molecular function	-
ZBTB17	7709	zinc finger and BTB domain containing 17	IRE1-mediated unfolded protein response	Biological process	-
ZZZ3	26009	zinc finger, ZZ-type containing 3	regulation of transcription, DNA-templated	Biological process	-
ABCC5	10057	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	hyaluronan metabolic process	Biological process	-
CSNK1A1	1452	casein kinase 1, alpha 1	phagocytosis	Biological process	-
TFF3	7033	trefoil factor 3 (intestinal)	protein binding	Molecular function	25416956
MT3	4504	metallothionein 3	cellular response to oxidative stress	Biological process	20039155
MCFD2	90411	multiple coagulation factor deficiency 2	protein N-linked glycosylation via asparagine	Biological process	-
CNTROB	116840	centrobin, centrosomal BRCA2 interacting protein	centrosome	Cellular component	21576394
ADD1	118	adducin 1 (alpha)	cytosol	Cellular component	-
BAD	572	BCL2-associated agonist of cell death	positive regulation of neuron death	Biological process	-
SYCP3	50511	synaptonemal complex protein 3	spermatogenesis, exchange of chromosomal proteins	Biological process	14643120
STIL	6491	SCL/TAL1 interrupting locus	mitotic spindle checkpoint	Biological process	-
PCBD1	5092	pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha	transcription coactivator activity	Molecular function	-
CCDC28B	79140	coiled-coil domain containing 28B	cytoplasm	Cellular component	-
PER2	8864	period circadian clock 2	pre-mRNA binding	Molecular function	-
HHLA2	11148	HERV-H LTR-associating 2	protein binding	Molecular function	23784006
EP300	2033	E1A binding protein p300	RNA polymerase II activating transcription factor binding	Molecular function	20018936
ZNF429	353088	zinc finger protein 429	transcription, DNA-templated	Biological process	-
GRHL1	29841	grainyhead-like 1 (Drosophila)	transcription regulatory region DNA binding	Molecular function	18288204
COL5A1	1289	collagen, type V, alpha 1	extracellular matrix organization	Biological process	-
GPR78	27201	G protein-coupled receptor 78	plasma membrane	Cellular component	-
SPARC	6678	secreted protein, acidic, cysteine-rich (osteonectin)	platelet alpha granule membrane	Cellular component	1737102
SLC35A1	10559	solute carrier family 35 (CMP-sialic acid transporter), member A1	cellular protein metabolic process	Biological process	-
SIRT2	22933	sirtuin 2	regulation of exit from mitosis	Biological process	12697818
PGLYRP2	114770	peptidoglycan recognition protein 2	innate immune response	Biological process	11461926
RAC1	5879	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	GTP-dependent protein binding	Molecular function	-
NOTCH3	4854	notch 3	enzyme binding	Molecular function	-
OR10P1	121130	olfactory receptor, family 10, subfamily P, member 1	G-protein coupled receptor activity	Molecular function	-
OR5B2	390190	olfactory receptor, family 5, subfamily B, member 2	plasma membrane	Cellular component	-
SFRP1	6422	secreted frizzled-related protein 1	plasma membrane	Cellular component	-
GPER1	2852	G protein-coupled estrogen receptor 1	plasma membrane	Cellular component	-
HLA-DPB1	3115	major histocompatibility complex, class II, DP beta 1	positive regulation of interferon-gamma production	Biological process	20356827
KRT17	3872	keratin 17, type I	epidermis development	Biological process	7539673
PRC1	9055	protein regulator of cytokinesis 1	spindle	Cellular component	17351640
MED12L	116931	mediator complex subunit 12-like	transcription factor binding	Molecular function	-
CASP16	197350	caspase 16, apoptosis-related cysteine peptidase (putative)	extrinsic apoptotic signaling pathway in absence of ligand	Biological process	-
CHD7	55636	chromodomain helicase DNA binding protein 7	olfactory bulb development	Biological process	-
PADI4	23569	peptidyl arginine deiminase, type IV	histone citrullination	Biological process	15339660
CAT	847	catalase	cholesterol metabolic process	Biological process	-
LYN	4067	LYN proto-oncogene, Src family tyrosine kinase	negative regulation of MAP kinase activity	Biological process	-
CNNM1	26507	cyclin and CBS domain divalent metal cation transport mediator 1	ion transport	Biological process	-
COX5B	1329	cytochrome c oxidase subunit Vb	small molecule metabolic process	Biological process	-
ATM	472	ATM serine/threonine kinase	replicative senescence	Biological process	15149599
ZNF443	10224	zinc finger protein 443	apoptotic process	Biological process	9731181
LEFTY1	10637	left-right determination factor 1	regulation of apoptotic process	Biological process	-
WNT7B	7477	wingless-type MMTV integration site family, member 7B	metanephros morphogenesis	Biological process	-
OASL	8638	2'-5'-oligoadenylate synthetase-like	cytosol	Cellular component	-
MAP3K12	7786	mitogen-activated protein kinase kinase kinase 12	intracellular signal transduction	Biological process	7983011
CENPB	1059	centromere protein B, 80kDa	nucleus	Cellular component	-
CMKLR1	1240	chemerin chemokine-like receptor 1	chemotaxis	Biological process	14530373
SHANK1	50944	SH3 and multiple ankyrin repeat domains 1	cytoskeletal anchoring at plasma membrane	Biological process	10551867
PPP2R4	5524	protein phosphatase 2A activator, regulatory subunit 4	protein phosphatase type 2A complex	Cellular component	10318862
CEP290	80184	centrosomal protein 290kDa	mitotic cell cycle	Biological process	-
FBXW11	23291	F-box and WD repeat domain containing 11	innate immune response	Biological process	-
APOA1	335	apolipoprotein A-I	small molecule metabolic process	Biological process	-
KIF2B	84643	kinesin family member 2B	nucleolus	Cellular component	-
CPEB3	22849	cytoplasmic polyadenylation element binding protein 3	RNA stem-loop binding	Molecular function	-
SPRY4	81848	sprouty homolog 4 (Drosophila)	Golgi apparatus	Cellular component	-
RAG2	5897	recombination activating gene 2	phosphatidylinositol binding	Molecular function	-
RBFOX3	146713	RNA binding protein, fox-1 homolog (C. elegans) 3	cytoplasm	Cellular component	-
IP6K3	117283	inositol hexakisphosphate kinase 3	protein phosphorylation	Biological process	11502751
GLUL	2752	glutamate-ammonia ligase	glutamate binding	Molecular function	-
POSTN	10631	periostin, osteoblast specific factor	extracellular matrix organization	Biological process	-
ANAPC11	51529	anaphase promoting complex subunit 11	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
BPNT1	10380	3'(2'), 5'-bisphosphate nucleotidase 1	small molecule metabolic process	Biological process	-
EGFR	1956	epidermal growth factor receptor	signal transduction	Biological process	-
PFDN6	10471	prefoldin subunit 6	cellular protein metabolic process	Biological process	-
MTHFD1	4522	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase	small molecule metabolic process	Biological process	-
AGO1	26523	argonaute RISC catalytic component 1	cytoplasmic mRNA processing body	Cellular component	-
PRMT8	56341	protein arginine methyltransferase 8	regulation of protein binding	Biological process	16051612
ISL1	3670	ISL LIM homeobox 1	pancreas development	Biological process	-
AKAP1	8165	A kinase (PRKA) anchor protein 1	blood coagulation	Biological process	-
ZBTB8B	728116	zinc finger and BTB domain containing 8B	metal ion binding	Molecular function	-
INF2	64423	inverted formin, FH2 and WH2 domain containing	nucleus	Cellular component	-
LPL	4023	lipoprotein lipase	extracellular matrix	Cellular component	-
GMFB	2764	glia maturation factor, beta	enzyme activator activity	Molecular function	8798479
SYT11	23208	synaptotagmin XI	negative regulation of neurotransmitter secretion	Biological process	21563316
SGOL1	151648	shugoshin-like 1 (S. pombe)	spindle pole	Cellular component	18331714
LAMTOR5	10542	late endosomal/lysosomal adaptor, MAPK and MTOR activator 5	positive regulation of GTPase activity	Biological process	22980980
TAF1B	9014	TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa	RNA polymerase I core factor complex	Cellular component	21921198
PKHD1	5314	polycystic kidney and hepatic disease 1 (autosomal recessive)	homeostatic process	Biological process	11919560
EXOC5	10640	exocyst complex component 5	organelle organization	Biological process	-
CYHR1	50626	cysteine/histidine-rich 1	nuclear envelope	Cellular component	-
PSMB4	5692	proteasome (prosome, macropain) subunit, beta type, 4	cytosol	Cellular component	-
CCDC92	80212	coiled-coil domain containing 92	centriole	Cellular component	22863007
CHMP6	79643	charged multivesicular body protein 6	mitotic metaphase plate congression	Biological process	20616062
RANGRF	29098	RAN guanine nucleotide release factor	caveola	Cellular component	23420830
TFAP2C	7022	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	sebaceous gland development	Biological process	-
KCNE5	23630	potassium channel, voltage gated subfamily E regulatory beta subunit 5	cardiac muscle contraction	Biological process	18313602
DAB2IP	153090	DAB2 interacting protein	signaling adaptor activity	Molecular function	20080667
CD40LG	959	CD40 ligand	positive regulation of endothelial cell apoptotic process	Biological process	12885753
CD14	929	CD14 molecule	positive regulation of cytokine secretion	Biological process	-
HEXIM2	124790	hexamethylene bis-acetamide inducible 2	cyclin-dependent protein serine/threonine kinase inhibitor activity	Molecular function	15713662
DCK	1633	deoxycytidine kinase	pyrimidine nucleoside salvage	Biological process	-
ZP3	7784	zona pellucida glycoprotein 3 (sperm receptor)	positive regulation of calcium ion import	Biological process	11751269
BPGM	669	2,3-bisphosphoglycerate mutase	extracellular exosome	Cellular component	23533145
ABCA8	10351	ATP-binding cassette, sub-family A (ABC1), member 8	lipid transport	Biological process	-
CELF4	56853	CUGBP, Elav-like family member 4	mRNA binding	Molecular function	-
HTR2C	3358	5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled	regulation of neurological system process	Biological process	-
DNAJB6	10049	DnaJ (Hsp40) homolog, subfamily B, member 6	cytoplasm	Cellular component	-
MMP7	4316	matrix metallopeptidase 7	collagen catabolic process	Biological process	-
ATF7IP	55729	activating transcription factor 7 interacting protein	DNA methylation	Biological process	12665582
TSPO	706	translocator protein (18kDa)	protein targeting to mitochondrion	Biological process	1326278
ADAP1	11033	ArfGAP with dual PH domains 1	positive regulation of GTPase activity	Biological process	-
OR8B12	219858	olfactory receptor, family 8, subfamily B, member 12	G-protein coupled receptor activity	Molecular function	-
RTN4	57142	reticulon 4	extracellular exosome	Cellular component	23376485
ITGAL	3683	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	cell-matrix adhesion	Biological process	19029120
GPX3	2878	glutathione peroxidase 3	extracellular space	Cellular component	1897960
TLR1	7096	toll-like receptor 1	signal transduction	Biological process	10426995
CDR1	1038	cerebellar degeneration-related protein 1, 34kDa	protein binding	Molecular function	25416956
HES1	3280	hes family bHLH transcription factor 1	ventricular septum morphogenesis	Biological process	-
RFWD3	55159	ring finger and WD repeat domain 3	protein binding	Molecular function	19549727
FYN	2534	FYN proto-oncogene, Src family tyrosine kinase	T cell costimulation	Biological process	-
OVCA2	124641	ovarian tumor suppressor candidate 2	cytoplasm	Cellular component	16368187
ZNF507	22847	zinc finger protein 507	metal ion binding	Molecular function	-
PAK4	10298	p21 protein (Cdc42/Rac)-activated kinase 4	Rac GTPase binding	Molecular function	-
FGF12	2257	fibroblast growth factor 12	regulation of membrane depolarization	Biological process	-
PPT1	5538	palmitoyl-protein thioesterase 1	cofactor metabolic process	Biological process	16542649
GPI	2821	glucose-6-phosphate isomerase	hemostasis	Biological process	7435496
PPP2R3C	55012	protein phosphatase 2, regulatory subunit B'', gamma	spindle	Cellular component	-
DYNC2LI1	51626	dynein, cytoplasmic 2, light intermediate chain 1	axonemal dynein complex	Cellular component	12802074
TESK2	10420	testis-specific kinase 2	protein tyrosine kinase activity	Molecular function	-
TRPC6	7225	transient receptor potential cation channel, subfamily C, member 6	cytosolic calcium ion homeostasis	Biological process	-
LIN7C	55327	lin-7 homolog C (C. elegans)	MPP7-DLG1-LIN7 complex	Cellular component	20702775
TBK1	29110	TANK-binding kinase 1	positive regulation of peptidyl-serine phosphorylation	Biological process	22412986
IRAK1	3654	interleukin-1 receptor-associated kinase 1	nucleotide-binding oligomerization domain containing signaling pathway	Biological process	-
HSPG2	3339	heparan sulfate proteoglycan 2	cartilage development involved in endochondral bone morphogenesis	Biological process	-
CREM	1390	cAMP responsive element modulator	spermatogenesis	Biological process	-
ZNF224	7767	zinc finger protein 224	nuclear membrane	Cellular component	-
CUL4B	8450	cullin 4B	damaged DNA binding	Molecular function	22334663
FGF12	2257	fibroblast growth factor 12	growth factor activity	Molecular function	-
YY1AP1	55249	YY1 associated protein 1	regulation of transcription, DNA-templated	Biological process	-
RPS19	6223	ribosomal protein S19	nucleolus	Cellular component	12586610
USP17L4	645402	ubiquitin specific peptidase 17-like family member 4	nucleus	Cellular component	-
ZNF611	81856	zinc finger protein 611	regulation of transcription, DNA-templated	Biological process	-
MYH11	4629	myosin, heavy chain 11, smooth muscle	muscle myosin complex	Cellular component	-
NSDHL	50814	NAD(P) dependent steroid dehydrogenase-like	lipid particle	Cellular component	14741744
ZFHX3	463	zinc finger homeobox 3	negative regulation of myoblast differentiation	Biological process	11312261
CRLF3	51379	cytokine receptor-like factor 3	cytoplasm	Cellular component	-
KLF8	11279	Kruppel-like factor 8	transcription, DNA-templated	Biological process	-
ADAMTS2	9509	ADAM metallopeptidase with thrombospondin type 1 motif, 2	proteinaceous extracellular matrix	Cellular component	-
NCBP2	22916	nuclear cap binding protein subunit 2, 20kDa	nucleoplasm	Cellular component	-
ATRN	8455	attractin	response to oxidative stress	Biological process	-
PRDM6	93166	PR domain containing 6	metal ion binding	Molecular function	-
STK39	27347	serine threonine kinase 39	positive regulation of potassium ion transport	Biological process	-
WT1	7490	Wilms tumor 1	regulation of organ formation	Biological process	-
NGF	4803	nerve growth factor (beta polypeptide)	protein binding	Molecular function	10490030
KDM6A	7403	lysine (K)-specific demethylase 6A	respiratory system process	Biological process	-
RPS4X	6191	ribosomal protein S4, X-linked	translation	Biological process	-
FAM118A	55007	family with sequence similarity 118, member A	protein binding	Molecular function	25416956
ARID1A	8289	AT rich interactive domain 1A (SWI-like)	DNA binding	Molecular function	10757798
SLC9A1	6548	solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1	positive regulation of cell growth	Biological process	-
ZMIZ2	83637	zinc finger, MIZ-type containing 2	nuclear replication fork	Cellular component	16051670
PASK	23178	PAS domain containing serine/threonine kinase	Golgi apparatus	Cellular component	-
SLC6A3	6531	solute carrier family 6 (neurotransmitter transporter), member 3	response to iron ion	Biological process	-
S100A7	6278	S100 calcium binding protein A7	positive regulation of ERK1 and ERK2 cascade	Biological process	18606705
PDE2A	5138	phosphodiesterase 2A, cGMP-stimulated	cellular response to mechanical stimulus	Biological process	-
CYP39A1	51302	cytochrome P450, family 39, subfamily A, polypeptide 1	oxidation-reduction process	Biological process	-
KLRK1	22914	killer cell lectin-like receptor subfamily K, member 1	innate immune response	Biological process	-
ECT2	1894	epithelial cell transforming 2	positive regulation of apoptotic process	Biological process	-
C1QBP	708	complement component 1, q subcomponent binding protein	blood coagulation, intrinsic pathway	Biological process	-
SLC36A1	206358	solute carrier family 36 (proton/amino acid symporter), member 1	L-proline transmembrane transporter activity	Molecular function	-
NTRK2	4915	neurotrophic tyrosine kinase, receptor, type 2	aging	Biological process	-
PLEKHG2	64857	pleckstrin homology domain containing, family G (with RhoGef domain) member 2	positive regulation of apoptotic process	Biological process	-
UBE2U	148581	ubiquitin-conjugating enzyme E2U (putative)	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological process	-
HAND1	9421	heart and neural crest derivatives expressed 1	ventricular cardiac muscle tissue morphogenesis	Biological process	18276607
PNOC	5368	prepronociceptin	extracellular region	Cellular component	-
SMARCAL1	50485	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1	DNA replication factor A complex	Cellular component	19793862
BAX	581	BCL2-associated X protein	BH3 domain binding	Molecular function	15705586
ZDHHC20	253832	zinc finger, DHHC-type containing 20	protein palmitoylation	Biological process	23034182
HIST2H4A	8370	histone cluster 2, H4a	regulation of gene expression, epigenetic	Biological process	-
SNCAIP	9627	synuclein, alpha interacting protein	ubiquitin protein ligase binding	Molecular function	15728840
MXD1	4084	MAX dimerization protein 1	nucleus	Cellular component	-
ATRN	8455	attractin	extracellular exosome	Cellular component	19056867
MRPL12	6182	mitochondrial ribosomal protein L12	positive regulation of transcription, DNA-templated	Biological process	17337445
DDX39B	7919	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B	U6 snRNP	Cellular component	18593880
ILVBL	10994	ilvB (bacterial acetolactate synthase)-like	membrane	Cellular component	19946888
IL4	3565	interleukin 4	negative regulation of apoptotic process	Biological process	-
RSPH4A	345895	radial spoke head 4 homolog A (Chlamydomonas)	axoneme assembly	Biological process	19200523
SBF2	81846	SET binding factor 2	phosphatase binding	Molecular function	-
CYP1B1	1545	cytochrome P450, family 1, subfamily B, polypeptide 1	steroid metabolic process	Biological process	22888116
SLC44A3	126969	solute carrier family 44, member 3	plasma membrane	Cellular component	-
ARL15	54622	ADP-ribosylation factor-like 15	GTP binding	Molecular function	-
KRAS	3845	Kirsten rat sarcoma viral oncogene homolog	response to mineralocorticoid	Biological process	-
FOXO4	4303	forkhead box O4	negative regulation of smooth muscle cell differentiation	Biological process	16054032
STARD3	10948	StAR-related lipid transfer (START) domain containing 3	late endosome membrane	Cellular component	-
DSCC1	79075	DNA replication and sister chromatid cohesion 1	regulation of DNA replication	Biological process	19907496
CPNE1	8904	copine I	negative regulation of DNA binding	Biological process	18212740
TSSK2	23617	testis-specific serine kinase 2	magnesium ion binding	Molecular function	-
GPR21	2844	G protein-coupled receptor 21	positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway	Biological process	-
TDO2	6999	tryptophan 2,3-dioxygenase	oxidation-reduction process	Biological process	-
KISS1	3814	KiSS-1 metastasis-suppressor	cytoskeleton organization	Biological process	9192814
TENM1	10178	teneurin transmembrane protein 1	cytoplasm	Cellular component	-
MB	4151	myoglobin	enucleate erythrocyte differentiation	Biological process	-
HSP90AB3P	3327	heat shock protein 90kDa alpha (cytosolic), class B member 3, pseudogene	unfolded protein binding	Molecular function	-
POM121	9883	POM121 transmembrane nucleoporin	cellular protein metabolic process	Biological process	-
KCNIP3	30818	Kv channel interacting protein 3, calsenilin	intracellular protein transport	Biological process	-
ADGRV1	84059	adhesion G protein-coupled receptor V1	nervous system development	Biological process	11606593
EGF	1950	epidermal growth factor	activation of transmembrane receptor protein tyrosine kinase activity	Biological process	9712850
OGT	8473	O-linked N-acetylglucosamine (GlcNAc) transferase	response to insulin	Biological process	18288188
AKR1B10	57016	aldo-keto reductase family 1, member B10 (aldose reductase)	doxorubicin metabolic process	Biological process	20837989
CXCL10	3627	chemokine (C-X-C motif) ligand 10	positive regulation of monocyte chemotaxis	Biological process	8608232
IL7R	3575	interleukin 7 receptor	homeostasis of number of cells	Biological process	-
BDKRB1	623	bradykinin receptor B1	positive regulation of release of sequestered calcium ion into cytosol	Biological process	-
WNT4	54361	wingless-type MMTV integration site family, member 4	cell fate commitment	Biological process	-
PIK3R2	5296	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	phosphatidylinositol phosphorylation	Biological process	-
PDHA2	5161	pyruvate dehydrogenase (lipoamide) alpha 2	pyruvate metabolic process	Biological process	16436377
CPSF1	29894	cleavage and polyadenylation specific factor 1, 160kDa	mRNA polyadenylation	Biological process	7590244
PATZ1	23598	POZ (BTB) and AT hook containing zinc finger 1	metal ion binding	Molecular function	-
PCGF3	10336	polycomb group ring finger 3	zinc ion binding	Molecular function	-
GOPC	57120	golgi-associated PDZ and coiled-coil motif containing	protein C-terminus binding	Molecular function	-
CYP2U1	113612	cytochrome P450, family 2, subfamily U, polypeptide 1	small molecule metabolic process	Biological process	-
CXCR4	7852	chemokine (C-X-C motif) receptor 4	neuron migration	Biological process	-
PLA2G7	7941	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	extracellular region	Cellular component	-
IRAK4	51135	interleukin-1 receptor-associated kinase 4	toll-like receptor 10 signaling pathway	Biological process	-
TCP1	6950	t-complex 1	acrosomal vesicle	Cellular component	-
DENND4B	9909	DENN/MADD domain containing 4B	nucleus	Cellular component	-
SLC24A1	9187	solute carrier family 24 (sodium/potassium/calcium exchanger), member 1	plasma membrane	Cellular component	-
OGDHL	55753	oxoglutarate dehydrogenase-like	protein binding	Molecular function	21988832
SLC38A4	55089	solute carrier family 38, member 4	symporter activity	Molecular function	-
FRG1	2483	FSHD region gene 1	Cajal body	Cellular component	-
CCDC23	374969	coiled-coil domain containing 23	protein secretion	Biological process	20736312
MICAL2	9645	microtubule associated monooxygenase, calponin and LIM domain containing 2	cytoskeleton organization	Biological process	24440334
EOMES	8320	eomesodermin	positive regulation of transcription, DNA-templated	Biological process	-
MTMR12	54545	myotubularin related protein 12	cytoplasm	Cellular component	-
NELFCD	51497	negative elongation factor complex member C/D	protein binding	Molecular function	12612062
SYTL3	94120	synaptotagmin-like 3	Rab GTPase binding	Molecular function	-
RIMS1	22999	regulating synaptic membrane exocytosis 1	positive regulation of inhibitory postsynaptic membrane potential	Biological process	-
MAP3K5	4217	mitogen-activated protein kinase kinase kinase 5	magnesium ion binding	Molecular function	17210579
DDX41	51428	DEAD (Asp-Glu-Ala-Asp) box polypeptide 41	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
RGL2	5863	ral guanine nucleotide dissociation stimulator-like 2	positive regulation of GTPase activity	Biological process	-
PFDN2	5202	prefoldin subunit 2	protein folding	Biological process	-
BMP7	655	bone morphogenetic protein 7	membrane-bounded vesicle	Cellular component	-
PAOX	196743	polyamine oxidase (exo-N4-amino)	xenobiotic metabolic process	Biological process	-
CASC5	57082	cancer susceptibility candidate 5	spindle assembly checkpoint	Biological process	17981135
HDAC6	10013	histone deacetylase 6	tubulin deacetylase activity	Molecular function	-
GALC	2581	galactosylceramidase	extracellular exosome	Cellular component	23376485
CCNL1	57018	cyclin L1	regulation of cyclin-dependent protein serine/threonine kinase activity	Biological process	-
TSSK2	23617	testis-specific serine kinase 2	spermatid development	Biological process	-
RASGRF1	5923	Ras protein-specific guanine nucleotide-releasing factor 1	positive regulation of Ras protein signal transduction	Biological process	-
PARN	5073	poly(A)-specific ribonuclease	nuclear-transcribed mRNA poly(A) tail shortening	Biological process	-
FGF5	2250	fibroblast growth factor 5	innate immune response	Biological process	-
ORC1	4998	origin recognition complex, subunit 1	nucleolus	Cellular component	-
TCF3	6929	transcription factor 3	response to drug	Biological process	-
MYO19	80179	myosin XIX	metabolic process	Biological process	-
PRKACA	5566	protein kinase, cAMP-dependent, catalytic, alpha	mitochondrion	Cellular component	-
RUNX2	860	runt-related transcription factor 2	negative regulation of smoothened signaling pathway	Biological process	-
ZFYVE21	79038	zinc finger, FYVE domain containing 21	focal adhesion	Cellular component	-
BANF1	8815	barrier to autointegration factor 1	nucleus	Cellular component	21630459
ITGB3	3690	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	cell-matrix adhesion	Biological process	24658351
OR2C1	4993	olfactory receptor, family 2, subfamily C, member 1	detection of chemical stimulus involved in sensory perception of smell	Biological process	9847080
CIB2	10518	calcium and integrin binding family member 2	neuromuscular junction	Cellular component	-
CAMTA2	23125	calmodulin binding transcription activator 2	histone deacetylase binding	Molecular function	16678093
POLR1B	84172	polymerase (RNA) I polypeptide B, 128kDa	transcription from RNA polymerase I promoter	Biological process	-
CKAP5	9793	cytoskeleton associated protein 5	cytosol	Cellular component	-
GPN1	11321	GPN-loop GTPase 1	nucleus	Cellular component	-
NUDT19	390916	nudix (nucleoside diphosphate linked moiety X)-type motif 19	metabolic process	Biological process	-
HES5	388585	hes family bHLH transcription factor 5	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
CLIC1	1192	chloride intracellular channel 1	protein binding	Molecular function	12163479
THBS1	7057	thrombospondin 1	behavioral response to pain	Biological process	-
DPAGT1	1798	dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)	endoplasmic reticulum membrane	Cellular component	-
ACR	49	acrosin	response to steroid hormone	Biological process	-
SMYD3	64754	SET and MYND domain containing 3	histone lysine methylation	Biological process	-
SRC	6714	SRC proto-oncogene, non-receptor tyrosine kinase	negative regulation of focal adhesion assembly	Biological process	-
GHR	2690	growth hormone receptor	JAK-STAT cascade involved in growth hormone signaling pathway	Biological process	-
SLC4A11	83959	solute carrier family 4, sodium borate transporter, member 11	borate transmembrane transporter activity	Molecular function	15525507
TRIAP1	51499	TP53 regulated inhibitor of apoptosis 1	negative regulation of release of cytochrome c from mitochondria	Biological process	23931759
MYH9	4627	myosin, heavy chain 9, non-muscle	protein anchor	Molecular function	16403913
PRPF19	27339	pre-mRNA processing factor 19	RNA splicing	Biological process	-
CETN2	1069	centrin, EF-hand protein, 2	protein binding	Molecular function	16760425
ABCC2	1244	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	response to heat	Biological process	-
MSL3	10943	male-specific lethal 3 homolog (Drosophila)	nucleoplasm	Cellular component	-
ZNRF3	84133	zinc and ring finger 3	integral component of plasma membrane	Cellular component	22575959
MAPK1	5594	mitogen-activated protein kinase 1	mitogen-activated protein kinase kinase kinase binding	Molecular function	-
GIPR	2696	gastric inhibitory polypeptide receptor	positive regulation of insulin secretion	Biological process	-
Sep-06	23157	septin 6	spindle	Cellular component	-
HSPA7	3311	heat shock 70kDa protein 7 (HSP70B)	molecular_function	Molecular function	-
SLAMF8	56833	SLAM family member 8	regulation of NAD(P)H oxidase activity	Biological process	-
CSRNP3	80034	cysteine-serine-rich nuclear protein 3	transcription, DNA-templated	Biological process	-
CEP41	95681	centrosomal protein 41kDa	protein transport	Biological process	-
PSEN1	5663	presenilin 1	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	-
ENO1	2023	enolase 1, (alpha)	transcription corepressor activity	Molecular function	2005901
TANK	10010	TRAF family member-associated NFKB activator	innate immune response	Biological process	-
SLC11A2	4891	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2	ferrous iron transmembrane transporter activity	Molecular function	12734107
CUX1	1523	cut-like homeobox 1	lung development	Biological process	-
ELP4	26610	elongator acetyltransferase complex subunit 4	transcription elongation factor complex	Cellular component	11714725
MED30	90390	mediator complex subunit 30	nucleus	Cellular component	10235267
CTSB	1508	cathepsin B	extracellular region	Cellular component	-
CRCP	27297	CGRP receptor component	defense response to virus	Biological process	-
ZNF446	55663	zinc finger protein 446	transcription from RNA polymerase II promoter	Biological process	-
GATA3	2625	GATA binding protein 3	response to drug	Biological process	-
SEC31A	22872	SEC31 homolog A (S. cerevisiae)	IRE1-mediated unfolded protein response	Biological process	-
AIP	9049	aryl hydrocarbon receptor interacting protein	cytoplasm	Cellular component	-
KLF6	1316	Kruppel-like factor 6	transcription, DNA-templated	Biological process	-
AIM2	9447	absent in melanoma 2	positive regulation of interleukin-1 beta secretion	Biological process	19158679
CAT	847	catalase	response to reactive oxygen species	Biological process	-
LPA	4018	lipoprotein, Lp(a)	lipid metabolic process	Biological process	8047165
AQP3	360	aquaporin 3 (Gill blood group)	integral component of membrane	Cellular component	17943189
BPIFC	254240	BPI fold containing family C	extracellular space	Cellular component	-
DIABLO	56616	diablo, IAP-binding mitochondrial protein	apoptotic process	Biological process	-
ADAM10	102	ADAM metallopeptidase domain 10	negative regulation of cell adhesion	Biological process	8694785
ABCD2	225	ATP-binding cassette, sub-family D (ALD), member 2	integral component of membrane	Cellular component	-
GTF2F2	2963	general transcription factor IIF, polypeptide 2, 30kDa	microtubule cytoskeleton	Cellular component	-
LHX1	3975	LIM homeobox 1	transcription from RNA polymerase II promoter	Biological process	-
SLC20A1	6574	solute carrier family 20 (phosphate transporter), member 1	phosphate-containing compound metabolic process	Biological process	8041748
TAL2	6887	T-cell acute lymphocytic leukemia 2	DNA binding	Molecular function	1763056
DCLK1	9201	doublecortin-like kinase 1	response to virus	Biological process	16548883
TPCN1	53373	two pore segment channel 1	membrane depolarization during action potential	Biological process	-
CHM	1121	choroideremia (Rab escort protein 1)	GTPase activator activity	Molecular function	-
RNLS	55328	renalase, FAD-dependent amine oxidase	response to epinephrine	Biological process	-
ATAD2B	54454	ATPase family, AAA domain containing 2B	nucleus	Cellular component	24561620
PPP1R9B	84687	protein phosphatase 1, regulatory subunit 9B	nucleoplasm	Cellular component	11278317
SERPINB3	6317	serpin peptidase inhibitor, clade B (ovalbumin), member 3	protease binding	Molecular function	21383048
TP53	7157	tumor protein p53	positive regulation of transcription, DNA-templated	Biological process	20096447
USP9X	8239	ubiquitin specific peptidase 9, X-linked	cytosol	Cellular component	-
GDF3	9573	growth differentiation factor 3	skeletal system development	Biological process	19864492
ZNF275	10838	zinc finger protein 275	nucleus	Cellular component	-
NRAS	4893	neuroblastoma RAS viral (v-ras) oncogene homolog	innate immune response	Biological process	-
FBXW8	26259	F-box and WD repeat domain containing 8	spongiotrophoblast layer development	Biological process	-
WDR48	57599	WD repeat domain 48	protein deubiquitination	Biological process	18082604
ITGAL	3683	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	Biological process	2477710
COL15A1	1306	collagen, type XV, alpha 1	endoplasmic reticulum lumen	Cellular component	-
AGPAT3	56894	1-acylglycerol-3-phosphate O-acyltransferase 3	cellular lipid metabolic process	Biological process	-
CXCL2	2920	chemokine (C-X-C motif) ligand 2	extracellular region	Cellular component	-
TUSC3	7991	tumor suppressor candidate 3	post-translational protein modification	Biological process	-
TRIM22	10346	tripartite motif containing 22	defense response to virus	Biological process	-
ZNF573	126231	zinc finger protein 573	transcription, DNA-templated	Biological process	-
SNX9	51429	sorting nexin 9	endosome	Cellular component	-
GDF6	392255	growth differentiation factor 6	growth	Biological process	-
F2R	2149	coagulation factor II (thrombin) receptor	positive regulation of interleukin-6 secretion	Biological process	11447194
LPIN3	64900	lipin 3	transcription coactivator activity	Molecular function	-
TERF1	7013	telomeric repeat binding factor (NIMA-interacting) 1	protein homodimerization activity	Molecular function	15608617
ZNF664-FAM101A	100533183	filamin-interacting protein FAM101A	cytoplasm	Cellular component	-
DUSP21	63904	dual specificity phosphatase 21	peptidyl-tyrosine dephosphorylation	Biological process	12408986
RAD54L	8438	RAD54-like (S. cerevisiae)	DNA binding	Molecular function	-
HHIPL2	79802	HHIP-like 2	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor	Molecular function	-
ITGA3	3675	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	collagen binding	Molecular function	-
IL17RE	132014	interleukin 17 receptor E	inflammatory response	Biological process	-
JPH3	57338	junctophilin 3	junctional membrane complex	Cellular component	-
BCHE	590	butyrylcholinesterase	response to glucocorticoid	Biological process	-
FLOT2	2319	flotillin 2	ionotropic glutamate receptor binding	Molecular function	-
LMX1B	4010	LIM homeobox transcription factor 1, beta	dorsal/ventral pattern formation	Biological process	-
F7	2155	coagulation factor VII (serum prothrombin conversion accelerator)	protein binding	Molecular function	15522303
SLC34A2	10568	solute carrier family 34 (type II sodium/phosphate cotransporter), member 2	protein domain specific binding	Molecular function	-
RANBP9	10048	RAN binding protein 9	microtubule nucleation	Biological process	12220523
FOXD4L5	653427	forkhead box D4-like 5	transcription from RNA polymerase II promoter	Biological process	-
CCNE1	898	cyclin E1	cyclin-dependent protein kinase holoenzyme complex	Cellular component	-
SDF4	51150	stromal cell derived factor 4	bleb	Cellular component	-
HEG1	57493	heart development protein with EGF-like domains 1	positive regulation of fibroblast growth factor production	Biological process	-
DRD3	1814	dopamine receptor D3	regulation of blood volume by renin-angiotensin	Biological process	-
SLC2A8	29988	solute carrier family 2 (facilitated glucose transporter), member 8	male meiosis I	Biological process	-
NPL	80896	N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)	N-acetylneuraminate lyase activity	Molecular function	-
SHARPIN	81858	SHANK-associated RH domain interactor	dendrite	Cellular component	-
ZFP36	7538	ZFP36 ring finger protein	cytoplasm	Cellular component	10330172
MMP2	4313	matrix metallopeptidase 2	extracellular region	Cellular component	-
FBXW7	55294	F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase	positive regulation of ubiquitin-protein transferase activity	Biological process	12628165
NCOA6	23054	nuclear receptor coactivator 6	ligand-dependent nuclear receptor transcription coactivator activity	Molecular function	11443112
CLU	1191	clusterin	regulation of beta-amyloid clearance	Biological process	24446231
HTR3A	3359	5-hydroxytryptamine (serotonin) receptor 3A, ionotropic	plasma membrane	Cellular component	-
BBC3	27113	BCL2 binding component 3	positive regulation of neuron apoptotic process	Biological process	-
GCNT3	9245	glucosaminyl (N-acetyl) transferase 3, mucin type	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity	Molecular function	-
DEFB124	245937	defensin, beta 124	extracellular region	Cellular component	-
DTD2	112487	D-tyrosyl-tRNA deacylase 2 (putative)	aminoacyl-tRNA editing activity	Molecular function	-
PIAS3	10401	protein inhibitor of activated STAT, 3	response to hormone	Biological process	-
S100A12	6283	S100 calcium binding protein A12	inflammatory response	Biological process	-
KCNE1	3753	potassium channel, voltage gated subfamily E regulatory beta subunit 1	ventricular cardiac muscle cell action potential	Biological process	9354802
SLC12A5	57468	solute carrier family 12 (potassium/chloride transporter), member 5	ion transport	Biological process	-
EPHX2	2053	epoxide hydrolase 2, cytoplasmic	positive regulation of gene expression	Biological process	18974052
HSPA5	3309	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	regulation of IRE1-mediated unfolded protein response	Biological process	22934019
CLCNKB	1188	chloride channel, voltage-sensitive Kb	regulation of anion transmembrane transport	Biological process	8041726
ACTB	60	actin, beta	NuA4 histone acetyltransferase complex	Cellular component	10966108
CCR7	1236	chemokine (C-C motif) receptor 7	positive regulation of T cell costimulation	Biological process	-
ADAMTS13	11093	ADAM metallopeptidase with thrombospondin type 1 motif, 13	proteinaceous extracellular matrix	Cellular component	11557746
PSMB5	5693	proteasome (prosome, macropain) subunit, beta type, 5	nucleus	Cellular component	-
ARHGDIA	396	Rho GDP dissociation inhibitor (GDI) alpha	positive regulation of GTPase activity	Biological process	-
WDTC1	23038	WD and tetratricopeptide repeats 1	negative regulation of fatty acid biosynthetic process	Biological process	-
BTBD1	53339	BTB (POZ) domain containing 1	cytoplasmic mRNA processing body	Cellular component	12878161
GRPEL1	80273	GrpE-like 1, mitochondrial (E. coli)	protein folding	Biological process	-
CCNT1	904	cyclin T1	protein phosphorylation	Biological process	16109376
PLSCR3	57048	phospholipid scramblase 3	integral component of membrane	Cellular component	-
FAF1	11124	Fas (TNFRSF6) associated factor 1	positive regulation of protein complex assembly	Biological process	15688372
NADK	65220	NAD kinase	NADP biosynthetic process	Biological process	-
TUBA4A	7277	tubulin, alpha 4a	structural constituent of cytoskeleton	Molecular function	-
SLC47A1	55244	solute carrier family 47 (multidrug and toxin extrusion), member 1	transmembrane transport	Biological process	-
TCAP	8557	titin-cap	response to muscle stretch	Biological process	17921333
NKX6-2	84504	NK6 homeobox 2	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification	Biological process	-
ARRB1	408	arrestin, beta 1	negative regulation of protein ubiquitination	Biological process	16378096
DDB2	1643	damage-specific DNA binding protein 2, 48kDa	Cul4B-RING E3 ubiquitin ligase complex	Cellular component	22334663
SPRR2E	6704	small proline-rich protein 2E	cytoplasm	Cellular component	3133554
PHF7	51533	PHD finger protein 7	protein binding	Molecular function	25416956
NOS1	4842	nitric oxide synthase 1 (neuronal)	interaction with host	Biological process	-
NR1I2	8856	nuclear receptor subfamily 1, group I, member 2	RNA polymerase II regulatory region sequence-specific DNA binding	Molecular function	11114890
LIG3	3980	ligase III, DNA, ATP-dependent	double-strand break repair via nonhomologous end joining	Biological process	-
JUND	3727	jun D proto-oncogene	nuclear chromatin	Cellular component	-
GET4	51608	golgi to ER traffic protein 4 homolog (S. cerevisiae)	cytosol	Cellular component	20676083
UBE2L3	7332	ubiquitin-conjugating enzyme E2L 3	ubiquitin-protein transferase activity	Molecular function	8563171
SCARF1	8578	scavenger receptor class F, member 1	cholesterol catabolic process	Biological process	9395444
SLC22A13	9390	solute carrier family 22 (organic anion/urate transporter), member 13	integral component of plasma membrane	Cellular component	10072596
BRCA1	672	breast cancer 1, early onset	ubiquitin protein ligase binding	Molecular function	17873885
TMEM110	375346	transmembrane protein 110	integral component of membrane	Cellular component	-
LRRK2	120892	leucine-rich repeat kinase 2	positive regulation of MAP kinase activity	Biological process	23628791
BICD1	636	bicaudal D homolog 1 (Drosophila)	cytoskeletal adaptor activity	Molecular function	12447383
IL12B	3593	interleukin 12B	positive regulation of activation of JAK2 kinase activity	Biological process	12023369
FYB	2533	FYN binding protein	receptor binding	Molecular function	10747096
FAS	355	Fas cell surface death receptor	B cell mediated immunity	Biological process	-
STYX	6815	serine/threonine/tyrosine interacting protein	protein dephosphorylation	Biological process	-
SERPINA5	5104	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5	acrosin binding	Molecular function	7521127
SPARC	6678	secreted protein, acidic, cysteine-rich (osteonectin)	response to cAMP	Biological process	-
MANF	7873	mesencephalic astrocyte-derived neurotrophic factor	nucleus	Cellular component	21630459
IFT140	9742	intraflagellar transport 140	protein localization to cilium	Biological process	20889716
CYB561A3	220002	cytochrome b561 family, member A3	metal ion binding	Molecular function	-
ATP1B4	23439	ATPase, Na+/K+ transporting, beta 4 polypeptide	transcription initiation from RNA polymerase II promoter	Biological process	-
TRAF1	7185	TNF receptor-associated factor 1	cytoplasm	Cellular component	8069916
HAND1	9421	heart and neural crest derivatives expressed 1	angiogenesis	Biological process	-
PAX6	5080	paired box 6	histone acetyltransferase binding	Molecular function	-
HDAC1	3065	histone deacetylase 1	mitotic cell cycle	Biological process	-
MDP1	145553	magnesium-dependent phosphatase 1	metal ion binding	Molecular function	-
PTGIS	5740	prostaglandin I2 (prostacyclin) synthase	vitamin metabolic process	Biological process	-
KAT5	10524	K(lysine) acetyltransferase 5	viral process	Biological process	-
SFN	2810	stratifin	cytoplasmic vesicle membrane	Cellular component	-
SMARCA4	6597	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	protein complex	Cellular component	16217013
PPP1R16B	26051	protein phosphatase 1, regulatory subunit 16B	perinuclear region of cytoplasm	Cellular component	12055102
NUBP1	4682	nucleotide binding protein 1	iron-sulfur cluster binding	Molecular function	18573874
PPARGC1A	10891	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	ligand-dependent nuclear receptor binding	Molecular function	18798693
ABCA12	26154	ATP-binding cassette, sub-family A (ABC1), member 12	epidermal lamellar body	Cellular component	16007253
CHST14	113189	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14	carbohydrate biosynthetic process	Biological process	-
PHF6	84295	PHD finger protein 6	histone deacetylase binding	Molecular function	22720776
SLC11A1	6556	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1	response to interferon-gamma	Biological process	-
SRP68	6730	signal recognition particle 68kDa	translation	Biological process	-
SRPK3	26576	SRSF protein kinase 3	muscle tissue development	Biological process	-
EPHA7	2045	EPH receptor A7	axon guidance	Biological process	-
CSNK2A1	1457	casein kinase 2, alpha 1 polypeptide	positive regulation of cell proliferation	Biological process	20625391
IL33	90865	interleukin 33	positive regulation of immunoglobulin secretion	Biological process	-
MAGEA2B	266740	melanoma antigen family A2B	negative regulation of protein sumoylation	Biological process	22117195
MCOLN1	57192	mucolipin 1	transmembrane transport	Biological process	-
NT5C1A	84618	5'-nucleotidase, cytosolic IA	dephosphorylation	Biological process	11133996
HEY2	23493	hes-related family bHLH transcription factor with YRPW motif 2	ventricular trabecula myocardium morphogenesis	Biological process	-
PLD4	122618	phospholipase D family, member 4	phosphatidylinositol phospholipase C activity	Molecular function	-
CYTH1	9267	cytohesin 1	vesicle-mediated transport	Biological process	1511013
OR51A7	119687	olfactory receptor, family 51, subfamily A, member 7	olfactory receptor activity	Molecular function	-
PYGO1	26108	pygopus family PHD finger 1	post-embryonic development	Biological process	-
HSF2	3298	heat shock transcription factor 2	cytoplasm	Cellular component	-
NUP210	23225	nucleoporin 210kDa	nuclear pore	Cellular component	-
DNAJB1	3337	DnaJ (Hsp40) homolog, subfamily B, member 1	chaperone binding	Molecular function	21231916
NES	10763	nestin	G2/M transition of mitotic cell cycle	Biological process	19384922
PHYH	5264	phytanoyl-CoA 2-hydroxylase	mitochondrion	Cellular component	-
TRIM27	5987	tripartite motif containing 27	DNA binding	Molecular function	-
CLPS	1208	colipase, pancreatic	extracellular region	Cellular component	-
NPBWR1	2831	neuropeptides B/W receptor 1	integral component of membrane	Cellular component	12401809
MEF2C	4208	myocyte enhancer factor 2C	response to virus	Biological process	21170291
SERF2	10169	small EDRK-rich factor 2	biological_process	Biological process	-
SLC1A3	6507	solute carrier family 1 (glial high affinity glutamate transporter), member 3	cell projection	Cellular component	-
TSPO	706	translocator protein (18kDa)	steroid biosynthetic process	Biological process	-
TRIM21	6737	tripartite motif containing 21	protein binding	Molecular function	11461834
ROCK1	6093	Rho-associated, coiled-coil containing protein kinase 1	protein phosphorylation	Biological process	-
MAP1LC3B2	643246	microtubule-associated protein 1 light chain 3 beta 2	nucleophagy	Biological process	-
OGFRL1	79627	opioid growth factor receptor-like 1	receptor activity	Molecular function	-
HIST1H2AM	8336	histone cluster 1, H2am	enzyme binding	Molecular function	17980597
BRF1	2972	BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit	nucleoplasm	Cellular component	-
CCR3	1232	chemokine (C-C motif) receptor 3	chemokine receptor activity	Molecular function	10415069
IGLON5	402665	IgLON family member 5	neuron projection	Cellular component	-
GAA	2548	glucosidase, alpha; acid	vacuolar sequestering	Biological process	10931430
OTOP1	133060	otopetrin 1	inner ear morphogenesis	Biological process	-
VPS25	84313	vacuolar protein sorting 25 homolog (S. cerevisiae)	protein homodimerization activity	Molecular function	14519844
PHF6	84295	PHD finger protein 6	nucleolus	Cellular component	-
EVI5	7813	ecotropic viral integration site 5	positive regulation of GTPase activity	Biological process	17562788
NOL6	65083	nucleolar protein 6 (RNA-associated)	small-subunit processome	Cellular component	-
FOXC2	2303	forkhead box C2	sequence-specific DNA binding	Molecular function	16081467
SPHK1	8877	sphingosine kinase 1	positive regulation of peptidyl-threonine phosphorylation	Biological process	23106337
SCARB2	950	scavenger receptor class B, member 2	focal adhesion	Cellular component	21423176
IGF1R	3480	insulin-like growth factor 1 receptor	brain development	Biological process	-
SPIN2A	54466	spindlin family, member 2A	molecular_function	Molecular function	-
ZNF22	7570	zinc finger protein 22	zinc ion binding	Molecular function	1946370
TBX2	6909	T-box 2	negative regulation of cardiac chamber formation	Biological process	-
RBM14	10432	RNA binding motif protein 14	DNA recombination	Biological process	11443112
AGAP1	116987	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1	positive regulation of GTPase activity	Biological process	-
DDX3X	1654	DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked	RNA stem-loop binding	Molecular function	22872150
PSMB5	5693	proteasome (prosome, macropain) subunit, beta type, 5	stimulatory C-type lectin receptor signaling pathway	Biological process	-
B4GALT1	2683	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	filopodium	Cellular component	-
RAD54B	25788	RAD54 homolog B (S. cerevisiae)	DNA binding	Molecular function	-
GNB5	10681	guanine nucleotide binding protein (G protein), beta 5	protein binding	Molecular function	12606627
CORO7	79585	coronin 7	Golgi to endosome transport	Biological process	24768539
JAK3	3718	Janus kinase 3	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	Biological process	-
ITSN1	6453	intersectin 1 (SH3 domain protein)	synapse	Cellular component	-
CXCL8	3576	chemokine (C-X-C motif) ligand 8	intracellular signal transduction	Biological process	10734056
ZNF268	10795	zinc finger protein 268	positive regulation of protein homodimerization activity	Biological process	23091055
IGLC2	3538	immunoglobulin lambda constant 2 (Kern-Oz- marker)	extracellular space	Cellular component	22664934
ZSCAN5C	649137	zinc finger and SCAN domain containing 5C	regulation of transcription from RNA polymerase II promoter	Biological process	-
OOEP	441161	oocyte expressed protein	RNA binding	Molecular function	-
CNTN4	152330	contactin 4	extracellular region	Cellular component	-
PSMD13	5719	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	nucleus	Cellular component	21630459
PDCD6	10016	programmed cell death 6	calcium ion binding	Molecular function	-
ADAM9	8754	ADAM metallopeptidase domain 9	positive regulation of protein secretion	Biological process	17704059
PRKCD	5580	protein kinase C, delta	metal ion binding	Molecular function	-
PRDX3	10935	peroxiredoxin 3	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	18262354
CADM3	57863	cell adhesion molecule 3	cell-cell junction	Cellular component	12826663
ZNF354C	30832	zinc finger protein 354C	cytoplasm	Cellular component	-
CYP2A6	1548	cytochrome P450, family 2, subfamily A, polypeptide 6	drug metabolic process	Biological process	18356043
THBS1	7057	thrombospondin 1	inflammatory response	Biological process	23144964
RBM23	55147	RNA binding motif protein 23	nucleus	Cellular component	-
CACNA1B	774	calcium channel, voltage-dependent, N type, alpha 1B subunit	ion transmembrane transport	Biological process	-
APOA4	337	apolipoprotein A-IV	cholesterol metabolic process	Biological process	1935934
SRPR	6734	signal recognition particle receptor (docking protein)	GTPase activity	Molecular function	-
G6PC2	57818	glucose-6-phosphatase, catalytic, 2	gluconeogenesis	Biological process	-
BMP7	655	bone morphogenetic protein 7	metanephros development	Biological process	18437684
TNFRSF10B	8795	tumor necrosis factor receptor superfamily, member 10b	necroptotic process	Biological process	-
SPINK2	6691	serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)	extracellular region	Cellular component	-
MAN2A2	4122	mannosidase, alpha, class 2A, member 2	cellular protein metabolic process	Biological process	-
UBE2I	7329	ubiquitin-conjugating enzyme E2I	nucleoplasm	Cellular component	-
SLC25A36	55186	solute carrier family 25 (pyrimidine nucleotide carrier), member 36	mitochondrial inner membrane	Cellular component	-
HLCS	3141	holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)	nuclear matrix	Cellular component	14613969
AREL1	9870	apoptosis resistant E3 ubiquitin protein ligase 1	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	23479728
CACNA2D2	9254	calcium channel, voltage-dependent, alpha 2/delta subunit 2	calcium channel regulator activity	Molecular function	-
FXYD4	53828	FXYD domain containing ion transport regulator 4	transmembrane transport	Biological process	-
SLC38A7	55238	solute carrier family 38, member 7	histidine transport	Biological process	-
HLA-E	3133	major histocompatibility complex, class I, E	extracellular exosome	Cellular component	20458337
ZNF735	730291	zinc finger protein 735	DNA binding	Molecular function	-
EIF3G	8666	eukaryotic translation initiation factor 3, subunit G	cytosol	Cellular component	-
PGM2	55276	phosphoglucomutase 2	phosphopentomutase activity	Molecular function	17804405
KRT8	3856	keratin 8, type II	extracellular exosome	Cellular component	19199708
ORC4	5000	origin recognition complex, subunit 4	DNA replication origin binding	Molecular function	9353276
CTSH	1512	cathepsin H	endopeptidase activity	Molecular function	14766755
SLC26A7	115111	solute carrier family 26 (anion exchanger), member 7	bicarbonate transmembrane transporter activity	Molecular function	12736153
CUL3	8452	cullin 3	protein binding	Molecular function	12609982
CAT	847	catalase	metal ion binding	Molecular function	-
ATF2	1386	activating transcription factor 2	intra-S DNA damage checkpoint	Biological process	15916964
HIST1H1A	3024	histone cluster 1, H1a	nucleosome assembly	Biological process	-
HTRA2	27429	HtrA serine peptidase 2	execution phase of apoptosis	Biological process	18309324
DPYD	1806	dihydropyrimidine dehydrogenase	oxidation-reduction process	Biological process	-
XRCC3	7517	X-ray repair complementing defective repair in Chinese hamster cells 3	ATP binding	Molecular function	-
MRPS33	51650	mitochondrial ribosomal protein S33	mitochondrial translational elongation	Biological process	-
VN1R4	317703	vomeronasal 1 receptor 4	pheromone receptor activity	Molecular function	-
ATP5S	27109	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)	small molecule metabolic process	Biological process	-
POLH	5429	polymerase (DNA directed), eta	DNA repair	Biological process	-
ERN1	2081	endoplasmic reticulum to nucleus signaling 1	protein autophosphorylation	Biological process	19328063
PLOD3	8985	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3	procollagen galactosyltransferase activity	Molecular function	-
ALMS1	7840	Alstrom syndrome protein 1	cytosol	Cellular component	-
HSD3B7	80270	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	cellular_component	Cellular component	-
SCN9A	6335	sodium channel, voltage gated, type IX alpha subunit	neuronal action potential	Biological process	-
TULP3	7289	tubby like protein 3	bronchus morphogenesis	Biological process	-
STYK1	55359	serine/threonine/tyrosine kinase 1	plasma membrane	Cellular component	-
SERTAD2	9792	SERTA domain containing 2	nucleus	Cellular component	16098148
SLC38A7	55238	solute carrier family 38, member 7	L-methionine transmembrane transporter activity	Molecular function	-
CREB3L2	64764	cAMP responsive element binding protein 3-like 2	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
CYP11A1	1583	cytochrome P450, family 11, subfamily A, polypeptide 1	cellular response to fibroblast growth factor stimulus	Biological process	-
ARSD	414	arylsulfatase D	arylsulfatase activity	Molecular function	7720070
HOXB2	3212	homeobox B2	transcription, DNA-templated	Biological process	-
THY1	7070	Thy-1 cell surface antigen	GTPase activator activity	Molecular function	-
PLEKHA2	59339	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2	laminin binding	Molecular function	19786618
MAPKAPK2	9261	mitogen-activated protein kinase-activated protein kinase 2	TRIF-dependent toll-like receptor signaling pathway	Biological process	-
NUDC	10726	nudC nuclear distribution protein	cytosol	Cellular component	-
SOX11	6664	SRY (sex determining region Y)-box 11	RNA polymerase II transcription coactivator activity	Molecular function	-
KIF2A	3796	kinesin heavy chain member 2A	protein binding	Molecular function	18411309
METTL3	56339	methyltransferase like 3	circadian rhythm	Biological process	-
CSF2RB	1439	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	interleukin-5 receptor activity	Molecular function	9410898
RCAN1	1827	regulator of calcineurin 1	signal transduction	Biological process	8595418
OR5AC1	81431	olfactory receptor, family 5, subfamily AC, member 1 (gene/pseudogene)	olfactory receptor activity	Molecular function	-
ATF5	22809	activating transcription factor 5	post-embryonic development	Biological process	-
CDC42SE2	56990	CDC42 small effector 2	regulation of signal transduction	Biological process	10816584
PRDM6	93166	PR domain containing 6	protein homodimerization activity	Molecular function	-
ZFPM1	161882	zinc finger protein, FOG family member 1	nucleoplasm	Cellular component	-
USP17L5	728386	ubiquitin specific peptidase 17-like family member 5	endoplasmic reticulum	Cellular component	-
CXCL2	2920	chemokine (C-X-C motif) ligand 2	inflammatory response	Biological process	-
SKOR2	652991	SKI family transcriptional corepressor 2	nucleus	Cellular component	16200078
ATP6V1G2	534	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2	cellular iron ion homeostasis	Biological process	-
ADORA1	134	adenosine A1 receptor	negative regulation of long term synaptic depression	Biological process	-
MTF2	22823	metal response element binding transcription factor 2	nucleoplasm	Cellular component	-
APOBEC3G	60489	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G	cytosol	Cellular component	-
HLA-DOB	3112	major histocompatibility complex, class II, DO beta	endosome membrane	Cellular component	-
CYSTM1	84418	cysteine-rich transmembrane module containing 1	extracellular exosome	Cellular component	19056867
DUSP22	56940	dual specificity phosphatase 22	protein tyrosine/serine/threonine phosphatase activity	Molecular function	-
ADAR	103	adenosine deaminase, RNA-specific	membrane	Cellular component	19946888
GPR32	2854	G protein-coupled receptor 32	G-protein coupled receptor activity	Molecular function	-
ZEB1	6935	zinc finger E-box binding homeobox 1	nucleoplasm	Cellular component	-
NEU4	129807	sialidase 4	exo-alpha-(2->6)-sialidase activity	Molecular function	-
ASIP	434	agouti signaling protein	type 4 melanocortin receptor binding	Molecular function	-
LRRFIP1	9208	leucine rich repeat (in FLII) interacting protein 1	double-stranded RNA binding	Molecular function	9671805
RPL19	6143	ribosomal protein L19	nucleolus	Cellular component	-
RPL36AL	6166	ribosomal protein L36a-like	cytosolic large ribosomal subunit	Cellular component	-
PSMB4	5692	proteasome (prosome, macropain) subunit, beta type, 4	G1/S transition of mitotic cell cycle	Biological process	-
ATP1B3	483	ATPase, Na+/K+ transporting, beta 3 polypeptide	potassium ion import	Biological process	10636900
XIAP	331	X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase	inhibition of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	-
TAF13	6884	TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa	nucleolus	Cellular component	-
MSTN	2660	myostatin	transforming growth factor beta receptor signaling pathway	Biological process	-
ISYNA1	51477	inositol-3-phosphate synthase 1	inositol biosynthetic process	Biological process	-
MAPK3	5595	mitogen-activated protein kinase 3	extracellular exosome	Cellular component	23376485
SERPINA5	5104	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5	protein C inhibitor-coagulation factor V complex	Cellular component	6323392
GPX1	2876	glutathione peroxidase 1	arachidonic acid metabolic process	Biological process	-
BAG3	9531	BCL2-associated athanogene 3	protein stabilization	Biological process	-
MIB2	142678	mindbomb E3 ubiquitin protein ligase 2	positive regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	12761501
APMAP	57136	adipocyte plasma membrane associated protein	biological_process	Biological process	-
CASQ2	845	calsequestrin 2 (cardiac muscle)	negative regulation of ryanodine-sensitive calcium-release channel activity	Biological process	-
TRIM56	81844	tripartite motif containing 56	poly(A) RNA binding	Molecular function	22658674
NEUROD1	4760	neuronal differentiation 1	positive regulation of apoptotic process	Biological process	-
LRP6	4040	low density lipoprotein receptor-related protein 6	neural tube closure	Biological process	-
C15orf27	123591	chromosome 15 open reading frame 27	calcium ion import	Biological process	-
HEXB	3074	hexosaminidase B (beta polypeptide)	protein heterodimerization activity	Molecular function	6230359
LGR4	55366	leucine-rich repeat containing G protein-coupled receptor 4	metanephric nephron tubule morphogenesis	Biological process	-
RARA	5914	retinoic acid receptor, alpha	Sertoli cell fate commitment	Biological process	-
PPIAL4A	653505	peptidylprolyl isomerase A (cyclophilin A)-like 4A	extracellular exosome	Cellular component	23533145
HIST1H2BG	8339	histone cluster 1, H2bg	protein binding	Molecular function	25416956
FLOT1	10211	flotillin 1	lysosomal membrane	Cellular component	17897319
ZNF134	7693	zinc finger protein 134	transcription, DNA-templated	Biological process	-
SHROOM2	357	shroom family member 2	apical plasma membrane	Cellular component	-
CACNB4	785	calcium channel, voltage-dependent, beta 4 subunit	gamma-aminobutyric acid signaling pathway	Biological process	-
FOXG1	2290	forkhead box G1	nucleus	Cellular component	-
RPL8	6132	ribosomal protein L8	membrane	Cellular component	19946888
DMTN	2039	dematin actin binding protein	cytoskeleton organization	Biological process	7615546
SLC16A3	9123	solute carrier family 16 (monocarboxylate transporter), member 3	plasma membrane lactate transport	Biological process	-
SLC16A3	9123	solute carrier family 16 (monocarboxylate transporter), member 3	lactate transmembrane transporter activity	Molecular function	-
HAS2	3037	hyaluronan synthase 2	extracellular matrix assembly	Biological process	-
RPS10	6204	ribosomal protein S10	SRP-dependent cotranslational protein targeting to membrane	Biological process	-
PKD2	5311	polycystic kidney disease 2 (autosomal dominant)	positive regulation of nitric oxide biosynthetic process	Biological process	19265036
SLC11A1	6556	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1	lysosome	Cellular component	-
UBC	7316	ubiquitin C	nucleotide-binding oligomerization domain containing signaling pathway	Biological process	-
CHRDL2	25884	chordin-like 2	cartilage development	Biological process	-
PIK3R1	5295	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	positive regulation of tumor necrosis factor production	Biological process	-
ACTR3B	57180	ARP3 actin-related protein 3 homolog B (yeast)	Arp2/3 protein complex	Cellular component	-
MCOLN1	57192	mucolipin 1	receptor complex	Cellular component	23382219
SHMT2	6472	serine hydroxymethyltransferase 2 (mitochondrial)	mitochondrial matrix	Cellular component	11516159
KIF25-AS1	100505879	KIF25 antisense RNA 1	cellular_component	Cellular component	-
CS	1431	citrate synthase	cellular metabolic process	Biological process	-
TFDP2	7029	transcription factor Dp-2 (E2F dimerization partner 2)	sequence-specific DNA binding transcription factor activity	Molecular function	7784053
NMNAT2	23057	nicotinamide nucleotide adenylyltransferase 2	synapse	Cellular component	-
DNM1	1759	dynamin 1	plasma membrane	Cellular component	-
TP53	7157	tumor protein p53	cell aging	Biological process	12080348
FMR1	2332	fragile X mental retardation 1	mRNA binding	Molecular function	7692601
CNOT3	4849	CCR4-NOT transcription complex, subunit 3	cytosol	Cellular component	-
CHST6	4166	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6	small molecule metabolic process	Biological process	-
DHX34	9704	DEAH (Asp-Glu-Ala-His) box polypeptide 34	nuclear-transcribed mRNA catabolic process	Biological process	23828042
HIST2H2BD	337874	histone cluster 2, H2bd (pseudogene)	extracellular exosome	Cellular component	23376485
ABHD6	57406	abhydrolase domain containing 6	mitochondrion	Cellular component	-
PTGIS	5740	prostaglandin I2 (prostacyclin) synthase	endoplasmic reticulum membrane	Cellular component	-
PPP5C	5536	protein phosphatase 5, catalytic subunit	mitotic nuclear division	Biological process	7925273
DZIP1	22873	DAZ interacting zinc finger protein 1	protein complex	Cellular component	15081113
SHH	6469	sonic hedgehog	smoothened signaling pathway	Biological process	-
LSM5	23658	LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	Biological process	-
CAPN15	6650	calpain 15	cytoplasm	Cellular component	-
AP4S1	11154	adaptor-related protein complex 4, sigma 1 subunit	protein transporter activity	Molecular function	-
ATP1B1	481	ATPase, Na+/K+ transporting, beta 1 polypeptide	positive regulation of calcium:sodium antiporter activity	Biological process	-
P2RX4	5025	purinergic receptor P2X, ligand gated ion channel, 4	integral component of nuclear inner membrane	Cellular component	-
RPS25	6230	ribosomal protein S25	cytosolic small ribosomal subunit	Cellular component	15883184
PLN	5350	phospholamban	cardiac muscle tissue development	Biological process	-
VANGL2	57216	VANGL planar cell polarity protein 2	lateral sprouting involved in lung morphogenesis	Biological process	-
TTYH1	57348	tweety family member 1	volume-sensitive chloride channel activity	Molecular function	16219661
KLRC3	3823	killer cell lectin-like receptor subfamily C, member 3	cellular defense response	Biological process	9683661
PACSIN1	29993	protein kinase C and casein kinase substrate in neurons 1	neuron projection morphogenesis	Biological process	-
PPARGC1A	10891	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	positive regulation of histone acetylation	Biological process	14636573
STX7	8417	syntaxin 7	perinuclear region of cytoplasm	Cellular component	18570918
PSME3	10197	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)	antigen processing and presentation of peptide antigen via MHC class I	Biological process	-
NOL11	25926	nucleolar protein 11	poly(A) RNA binding	Molecular function	22658674
ABCA1	19	ATP-binding cassette, sub-family A (ABC1), member 1	cellular response to lipopolysaccharide	Biological process	-
CDK5RAP2	55755	CDK5 regulatory subunit associated protein 2	spindle pole	Cellular component	17959831
ADCYAP1	116	adenylate cyclase activating polypeptide 1 (pituitary)	female pregnancy	Biological process	10698193
ATP6V0D1	9114	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1	ion transmembrane transport	Biological process	-
TRAPPC2	6399	trafficking protein particle complex 2	Golgi apparatus	Cellular component	-
ASAP1	50807	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	protein binding	Molecular function	12029088
MYO6	4646	myosin VI	clathrin-coated endocytic vesicle	Cellular component	11447109
AZIN1	51582	antizyme inhibitor 1	negative regulation of protein catabolic process	Biological process	17900240
TP53	7157	tumor protein p53	gene expression	Biological process	-
ISG20L2	81875	interferon stimulated exonuclease gene 20kDa-like 2	nucleic acid phosphodiester bond hydrolysis	Biological process	-
HDGFRP3	50810	hepatoma-derived growth factor, related protein 3	cell proliferation	Biological process	10581169
CABIN1	23523	calcineurin binding protein 1	cell surface receptor signaling pathway	Biological process	9655484
PRKAR2B	5577	protein kinase, cAMP-dependent, regulatory, type II, beta	centrosome	Cellular component	21399614
RPAIN	84268	RPA interacting protein	DNA repair	Biological process	16135809
TNNI3	7137	troponin I type 3 (cardiac)	muscle filament sliding	Biological process	-
RAB14	51552	RAB14, member RAS oncogene family	Golgi stack	Cellular component	-
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	embryonic heart tube development	Biological process	-
CHRNB3	1142	cholinergic receptor, nicotinic, beta 3 (neuronal)	acetylcholine binding	Molecular function	-
MAP2K7	5609	mitogen-activated protein kinase kinase 7	MAP kinase kinase activity	Molecular function	9535930
HTT	3064	huntingtin	negative regulation of neuron apoptotic process	Biological process	-
ZC3H14	79882	zinc finger CCCH-type containing 14	nuclear speck	Cellular component	-
PDGFC	56034	platelet derived growth factor C	extracellular region	Cellular component	-
ALDH3A1	218	aldehyde dehydrogenase 3 family, member A1	plasma membrane	Cellular component	-
SFN	2810	stratifin	protein kinase binding	Molecular function	-
UBA52	7311	ubiquitin A-52 residue ribosomal protein fusion product 1	gene expression	Biological process	-
UBE2D1	7321	ubiquitin-conjugating enzyme E2D 1	innate immune response	Biological process	-
KSR2	283455	kinase suppressor of ras 2	intracellular signal transduction	Biological process	-
ATP2A1	487	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	positive regulation of mitochondrial calcium ion concentration	Biological process	19061639
ZNF431	170959	zinc finger protein 431	chromatin binding	Molecular function	-
PRKCZ	5590	protein kinase C, zeta	inflammatory response	Biological process	-
CLU	1191	clusterin	reverse cholesterol transport	Biological process	16682745
TIGAR	57103	TP53 induced glycolysis regulatory phosphatase	dephosphorylation	Biological process	-
AIP	9049	aryl hydrocarbon receptor interacting protein	nucleoplasm	Cellular component	-
MTRR	4552	5-methyltetrahydrofolate-homocysteine methyltransferase reductase	small molecule metabolic process	Biological process	-
RASA2	5922	RAS p21 protein activator 2	negative regulation of Ras protein signal transduction	Biological process	-
CEP55	55165	centrosomal protein 55kDa	membrane	Cellular component	19946888
HEYL	26508	hes-related family bHLH transcription factor with YRPW motif-like	cardiac ventricle morphogenesis	Biological process	-
AIPL1	23746	aryl hydrocarbon receptor interacting protein-like 1	farnesylated protein binding	Molecular function	14555765
SFRP5	6425	secreted frizzled-related protein 5	Wnt-protein binding	Molecular function	-
PSEN2	5664	presenilin 2	embryonic limb morphogenesis	Biological process	-
TBX3	6926	T-box 3	luteinizing hormone secretion	Biological process	12116211
SIDT1	54847	SID1 transmembrane family, member 1	dsRNA transport	Biological process	-
OR52N1	79473	olfactory receptor, family 52, subfamily N, member 1	olfactory receptor activity	Molecular function	-
TKFC	26007	triokinase/FMN cyclase	protein binding	Molecular function	25416956
CHGA	1113	chromogranin A	mast cell granule	Cellular component	21214543
CCDC23	374969	coiled-coil domain containing 23	negative regulation of protein ubiquitination	Biological process	20736312
ASIC1	41	acid sensing (proton gated) ion channel 1	response to acidic pH	Biological process	-
TEK	7010	TEK tyrosine kinase, endothelial	growth factor binding	Molecular function	-
CPXM2	119587	carboxypeptidase X (M14 family), member 2	proteolysis	Biological process	-
WWP1	11059	WW domain containing E3 ubiquitin protein ligase 1	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological process	-
FNTA	2339	farnesyltransferase, CAAX box, alpha	cytosol	Cellular component	-
ITGA2	3673	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	cell surface	Cellular component	19581412
HRH2	3274	histamine receptor H2	dopamine neurotransmitter receptor activity, coupled via Gs	Molecular function	-
CITED2	10370	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	liver development	Biological process	-
F2R	2149	coagulation factor II (thrombin) receptor	positive regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	12761501
IL1B	3553	interleukin 1, beta	negative regulation of lipid catabolic process	Biological process	19032770
CDC16	8881	cell division cycle 16	centrosome	Cellular component	7736578
PRLR	5618	prolactin receptor	activation of transmembrane receptor protein tyrosine kinase activity	Biological process	10585417
NPR1	4881	natriuretic peptide receptor 1	integral component of plasma membrane	Cellular component	12547834
KIF14	9928	kinesin family member 14	protein kinase binding	Molecular function	16431929
TCIRG1	10312	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3	transporter activity	Molecular function	8579597
CD7	924	CD7 molecule	transmembrane receptor protein tyrosine kinase signaling pathway	Biological process	11485208
ASL	435	argininosuccinate lyase	arginine biosynthetic process via ornithine	Biological process	-
CIB1	10519	calcium and integrin binding 1 (calmyrin)	positive regulation of cell migration	Biological process	-
C2CD4B	388125	C2 calcium-dependent domain containing 4B	calcium-dependent phospholipid binding	Molecular function	-
ATP5L	10632	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G	mitochondrial proton-transporting ATP synthase complex	Cellular component	12110673
KIF15	56992	kinesin family member 15	spindle	Cellular component	-
IRS4	8471	insulin receptor substrate 4	SH3/SH2 adaptor activity	Molecular function	9261155
UTP18	51096	UTP18 small subunit (SSU) processome component homolog (yeast)	Pwp2p-containing subcomplex of 90S preribosome	Cellular component	-
TBX3	6926	T-box 3	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	11689487
ANO7	50636	anoctamin 7	intracellular calcium activated chloride channel activity	Molecular function	21984732
RAB11B	9230	RAB11B, member RAS oncogene family	extracellular exosome	Cellular component	20458337
ELAVL4	1996	ELAV like neuron-specific RNA binding protein 4	RNA processing	Biological process	1655278
PSMC5	5705	proteasome (prosome, macropain) 26S subunit, ATPase, 5	positive regulation of canonical Wnt signaling pathway	Biological process	-
PSPC1	55269	paraspeckle component 1	paraspeckles	Cellular component	-
NPHS2	7827	nephrosis 2, idiopathic, steroid-resistant (podocin)	metanephric glomerular visceral epithelial cell development	Biological process	11786407
FKBP8	23770	FK506 binding protein 8, 38kDa	multicellular organism growth	Biological process	-
SETX	23064	senataxin	MAPK cascade	Biological process	21576111
POFUT1	23509	protein O-fucosyltransferase 1	O-glycan processing	Biological process	11698403
SEC23IP	11196	SEC23 interacting protein	poly(A) RNA binding	Molecular function	22658674
CUL7	9820	cullin 7	placenta development	Biological process	20139075
MPHOSPH8	54737	M-phase phosphoprotein 8	protein binding	Molecular function	20871592
RB1	5925	retinoblastoma 1	cell morphogenesis involved in neuron differentiation	Biological process	-
PML	5371	promyelocytic leukemia	defense response to virus	Biological process	-
CHCHD4	131474	coiled-coil-helix-coiled-coil-helix domain containing 4	mitochondrial DNA repair	Biological process	-
CDC42EP5	148170	CDC42 effector protein (Rho GTPase binding) 5	regulation of cell shape	Biological process	11035016
MYO19	80179	myosin XIX	actin binding	Molecular function	-
MYCBP2	23077	MYC binding protein 2, E3 ubiquitin protein ligase	membrane	Cellular component	19946888
ABL1	25	ABL proto-oncogene 1, non-receptor tyrosine kinase	peptidyl-tyrosine phosphorylation	Biological process	23626584
EGFR	1956	epidermal growth factor receptor	cellular response to amino acid stimulus	Biological process	-
SCUBE3	222663	signal peptide, CUB domain, EGF-like 3	protein binding	Molecular function	15234972
IL24	11009	interleukin 24	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	-
CXCL2	2920	chemokine (C-X-C motif) ligand 2	extracellular space	Cellular component	-
AMFR	267	autocrine motility factor receptor, E3 ubiquitin protein ligase	aging	Biological process	-
FIP1L1	81608	factor interacting with PAPOLA and CPSF1	protein binding	Molecular function	19224921
RNASE11	122651	ribonuclease, RNase A family, 11 (non-active)	nucleic acid phosphodiester bond hydrolysis	Biological process	-
UCHL5	51377	ubiquitin carboxyl-terminal hydrolase L5	regulation of transcription, DNA-templated	Biological process	-
CYB5R4	51167	cytochrome b5 reductase 4	cell development	Biological process	-
AIM1	202	absent in melanoma 1	cellular_component	Cellular component	-
TDRD10	126668	tudor domain containing 10	nucleotide binding	Molecular function	-
HNRNPA3	220988	heterogeneous nuclear ribonucleoprotein A3	ribonucleoprotein complex	Cellular component	8101480
PRKCA	5578	protein kinase C, alpha	negative regulation of adenylate cyclase activity	Biological process	-
NRP1	8829	neuropilin 1	negative regulation of neuron apoptotic process	Biological process	-
BBS4	585	Bardet-Biedl syndrome 4	dendrite development	Biological process	-
RAB11FIP5	26056	RAB11 family interacting protein 5 (class I)	Golgi membrane	Cellular component	-
AMTN	401138	amelotin	odontogenesis of dentin-containing tooth	Biological process	16304441
IKBKE	9641	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	protein binding	Molecular function	14743216
ESRRG	2104	estrogen-related receptor gamma	retinoic acid receptor activity	Molecular function	-
CSNK1A1	1452	casein kinase 1, alpha 1	Wnt signaling pathway	Biological process	-
CYSLTR1	10800	cysteinyl leukotriene receptor 1	positive regulation of angiogenesis	Biological process	-
ACVR1	90	activin A receptor, type I	positive regulation of bone mineralization	Biological process	18436533
GAPDH	2597	glyceraldehyde-3-phosphate dehydrogenase	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity	Molecular function	3170585
GMNN	51053	geminin, DNA replication inhibitor	transcription corepressor activity	Molecular function	-
PDPK1	5170	3-phosphoinositide dependent protein kinase 1	T cell costimulation	Biological process	-
CD55	1604	CD55 molecule, decay accelerating factor for complement (Cromer blood group)	complement activation, classical pathway	Biological process	-
VAX1	11023	ventral anterior homeobox 1	transcription, DNA-templated	Biological process	-
LAMB1	3912	laminin, beta 1	odontogenesis	Biological process	15894315
ISG20L2	81875	interferon stimulated exonuclease gene 20kDa-like 2	protein binding	Molecular function	16189514
P2RY1	5028	purinergic receptor P2Y, G-protein coupled, 1	integral component of plasma membrane	Cellular component	8630005
LGMN	5641	legumain	response to acidic pH	Biological process	-
ZSCAN21	7589	zinc finger and SCAN domain containing 21	positive regulation of transcription from RNA polymerase II promoter	Biological process	19549071
CFLAR	8837	CASP8 and FADD-like apoptosis regulator	negative regulation of myoblast fusion	Biological process	-
POLR3G	10622	polymerase (RNA) III (DNA directed) polypeptide G (32kD)	cytosol	Cellular component	-
RHO	6010	rhodopsin	plasma membrane	Cellular component	-
CERS1	10715	ceramide synthase 1	integral component of membrane	Cellular component	-
ACE	1636	angiotensin I converting enzyme	integral component of membrane	Cellular component	-
INPP5D	3635	inositol polyphosphate-5-phosphatase, 145kDa	phosphatidylinositol dephosphorylation	Biological process	-
G6PD	2539	glucose-6-phosphate dehydrogenase	NADP binding	Molecular function	15858258
SLC26A7	115111	solute carrier family 26 (anion exchanger), member 7	sulfate transport	Biological process	1183472
NAALAD2	10003	N-acetylated alpha-linked acidic dipeptidase 2	N-formylglutamate deformylase activity	Molecular function	-
FZD9	8326	frizzled class receptor 9	cytoplasm	Cellular component	19038973
RGS9	8787	regulator of G-protein signaling 9	nervous system development	Biological process	-
DLL4	54567	delta-like 4 (Drosophila)	blood vessel remodeling	Biological process	-
GRID2	2895	glutamate receptor, ionotropic, delta 2	ionotropic glutamate receptor activity	Molecular function	-
TCEB3	6924	transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)	nucleus	Cellular component	-
KIF9	64147	kinesin family member 9	microtubule binding	Molecular function	-
GABARAPL1	23710	GABA(A) receptor-associated protein like 1	mitochondrion degradation	Biological process	-
ANKRD23	200539	ankyrin repeat domain 23	nucleoplasm	Cellular component	-
CYP4F8	11283	cytochrome P450, family 4, subfamily F, polypeptide 8	iron ion binding	Molecular function	-
CRB2	286204	crumbs family member 2	membrane raft	Cellular component	20299451
RPL35A	6165	ribosomal protein L35a	tRNA binding	Molecular function	-
MEF2A	4205	myocyte enhancer factor 2A	muscle organ development	Biological process	1516833
PPP1R26	9858	protein phosphatase 1, regulatory subunit 26	protein binding	Molecular function	15231748
PTGFR	5737	prostaglandin F receptor (FP)	cytoplasm	Cellular component	18508192
RPS25	6230	ribosomal protein S25	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Biological process	-
HCRTR2	3062	hypocretin (orexin) receptor 2	phospholipase C-activating G-protein coupled receptor signaling pathway	Biological process	-
PLAG1	5324	pleiomorphic adenoma gene 1	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	10646861
ESR2	2100	estrogen receptor 2 (ER beta)	transcription initiation from RNA polymerase II promoter	Biological process	-
LGR6	59352	leucine-rich repeat containing G protein-coupled receptor 6	integral component of plasma membrane	Cellular component	-
FGD1	2245	FYVE, RhoGEF and PH domain containing 1	filopodium assembly	Biological process	8969170
TPTE2	93492	transmembrane phosphoinositide 3-phosphatase and tensin homolog 2	phospholipid metabolic process	Biological process	-
ANAPC7	51434	anaphase promoting complex subunit 7	protein K11-linked ubiquitination	Biological process	18485873
PKM	5315	pyruvate kinase, muscle	mitochondrion	Cellular component	20833797
GPR27	2850	G protein-coupled receptor 27	signal transduction	Biological process	10833454
FGD4	121512	FYVE, RhoGEF and PH domain containing 4	actin binding	Molecular function	-
SCP2	6342	sterol carrier protein 2	protein localization to plasma membrane	Biological process	12641450
GJB5	2709	gap junction protein, beta 5, 31.1kDa	cell communication	Biological process	-
TNF	7124	tumor necrosis factor	negative regulation of fat cell differentiation	Biological process	16464856
DTL	51514	denticleless E3 ubiquitin protein ligase homolog (Drosophila)	translesion synthesis	Biological process	-
GPX1	2876	glutathione peroxidase 1	purine nucleotide catabolic process	Biological process	-
NME7	29922	NME/NM23 family member 7	epithelial cilium movement	Biological process	-
FAP	2191	fibroblast activation protein, alpha	positive regulation of execution phase of apoptosis	Biological process	-
MAOA	4128	monoamine oxidase A	primary amine oxidase activity	Molecular function	-
MID2	11043	midline 2	protein ubiquitination	Biological process	-
ZSCAN22	342945	zinc finger and SCAN domain containing 22	biological_process	Biological process	-
BLCAP	10904	bladder cancer associated protein	apoptotic nuclear changes	Biological process	17031575
PREX1	57580	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	GTPase activator activity	Molecular function	12123595
GAN	8139	gigaxonin	protein binding	Molecular function	12147674
DGAT2	84649	diacylglycerol O-acyltransferase 2	endoplasmic reticulum membrane	Cellular component	-
TGFB2	7042	transforming growth factor, beta 2	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	Biological process	-
ZNF287	57336	zinc finger protein 287	transcription, DNA-templated	Biological process	-
C2CD5	9847	C2 calcium-dependent domain containing 5	positive regulation of glucose transport	Biological process	-
FZD10	11211	frizzled class receptor 10	integral component of plasma membrane	Cellular component	10448064
FOXRED1	55572	FAD-dependent oxidoreductase domain containing 1	biological_process	Biological process	-
IFT74	80173	intraflagellar transport 74	ciliary tip	Cellular component	-
MDM4	4194	MDM4, p53 regulator	nucleoplasm	Cellular component	-
BMPER	168667	BMP binding endothelial regulator	regulation of pathway-restricted SMAD protein phosphorylation	Biological process	18787191
SNCG	6623	synuclein, gamma (breast cancer-specific protein 1)	protein secretion	Biological process	-
RNASEH2B	79621	ribonuclease H2, subunit B	RNA phosphodiester bond hydrolysis, endonucleolytic	Biological process	-
NCEH1	57552	neutral cholesterol ester hydrolase 1	lipid catabolic process	Biological process	-
CENPA	1058	centromere protein A	chromatin binding	Molecular function	7962047
HSP90AA1	3320	heat shock protein 90kDa alpha (cytosolic), class A member 1	protein kinase binding	Molecular function	-
TRA2B	6434	transformer 2 beta homolog (Drosophila)	nucleotide binding	Molecular function	-
RESP18	389075	regulated endocrine-specific protein 18	secretory granule	Cellular component	-
ZBTB25	7597	zinc finger and BTB domain containing 25	sequence-specific DNA binding RNA polymerase II transcription factor activity	Molecular function	-
MEIOB	254528	meiosis specific with OB domains	female meiosis I	Biological process	-
GIT2	9815	G protein-coupled receptor kinase interacting ArfGAP 2	GTPase activator activity	Molecular function	-
HIGD2A	192286	HIG1 hypoxia inducible domain family, member 2A	negative regulation of apoptotic process	Biological process	21856340
SLC15A4	121260	solute carrier family 15 (oligopeptide transporter), member 4	L-histidine transmembrane transporter activity	Molecular function	-
BNIP3	664	BCL2/adenovirus E1B 19kDa interacting protein 3	GTPase binding	Molecular function	20436456
NCS1	23413	neuronal calcium sensor 1	cytosol	Cellular component	-
TRPV4	59341	transient receptor potential cation channel, subfamily V, member 4	calmodulin binding	Molecular function	12724311
RPS19	6223	ribosomal protein S19	cellular protein metabolic process	Biological process	-
TNF	7124	tumor necrosis factor	positive regulation of osteoclast differentiation	Biological process	17888176
CALCA	796	calcitonin-related polypeptide alpha	inflammatory response	Biological process	-
CHMP1B	57132	charged multivesicular body protein 1B	viral budding via host ESCRT complex	Biological process	24878737
RXRB	6257	retinoid X receptor, beta	steroid hormone mediated signaling pathway	Biological process	-
SP1	6667	Sp1 transcription factor	bHLH transcription factor binding	Molecular function	-
FERMT2	10979	fermitin family member 2	extrinsic component of cytoplasmic side of plasma membrane	Cellular component	21325030
CD86	942	CD86 molecule	protein binding	Molecular function	11279501
LIPT2	387787	lipoyl(octanoyl) transferase 2 (putative)	mitochondrion	Cellular component	-
HPD	3242	4-hydroxyphenylpyruvate dioxygenase	L-phenylalanine catabolic process	Biological process	-
MED4	29079	mediator complex subunit 4	androgen receptor signaling pathway	Biological process	12218053
APOA4	337	apolipoprotein A-IV	chylomicron remodeling	Biological process	2307668
TNFRSF12A	51330	tumor necrosis factor receptor superfamily, member 12A	positive regulation of apoptotic process	Biological process	21525013
ISL1	3670	ISL LIM homeobox 1	negative regulation of neuron apoptotic process	Biological process	-
UPP2	151531	uridine phosphorylase 2	pyrimidine nucleobase metabolic process	Biological process	-
GATA3	2625	GATA binding protein 3	negative regulation of cell cycle	Biological process	20189993
SNX25	83891	sorting nexin 25	termination of G-protein coupled receptor signaling pathway	Biological process	-
ASCL4	121549	achaete-scute family bHLH transcription factor 4	protein binding	Molecular function	25416956
TFAP2A	7020	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	11278550
OR1L1	26737	olfactory receptor, family 1, subfamily L, member 1	integral component of membrane	Cellular component	-
SFRP1	6422	secreted frizzled-related protein 1	Wnt-activated receptor activity	Molecular function	-
DENND2D	79961	DENN/MADD domain containing 2D	Rab guanyl-nucleotide exchange factor activity	Molecular function	20937701
IL27	246778	interleukin 27	regulation of T cell proliferation	Biological process	-
DEFB109P1	245912	defensin, beta 109, pseudogene 1	extracellular region	Cellular component	-
USP37	57695	ubiquitin specific peptidase 37	nucleus	Cellular component	-
NEK3	4752	NIMA-related kinase 3	cell division	Biological process	-
GATA6	2627	GATA binding protein 6	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity	Molecular function	-
RIMKLB	57494	ribosomal modification protein rimK-like family member B	N-acetyl-L-aspartate-L-glutamate ligase activity	Molecular function	-
UBE2D1	7321	ubiquitin-conjugating enzyme E2D 1	cytoplasm	Cellular component	18845142
C2CD4A	145741	C2 calcium-dependent domain containing 4A	synaptic vesicle exocytosis	Biological process	-
MAPKAPK3	7867	mitogen-activated protein kinase-activated protein kinase 3	nucleoplasm	Cellular component	-
PSRC1	84722	proline/serine-rich coiled-coil 1	positive regulation of microtubule polymerization	Biological process	12427559
CTSK	1513	cathepsin K	positive regulation of protein targeting to mitochondrion	Biological process	24912190
NEDD4L	23327	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase	negative regulation of transforming growth factor beta receptor signaling pathway	Biological process	-
SLC26A6	65010	solute carrier family 26 (anion exchanger), member 6	cellular response to fructose stimulus	Biological process	-
MKX	283078	mohawk homeobox	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
CNIH2	254263	cornichon family AMPA receptor auxiliary protein 2	localization within membrane	Biological process	-
PSMA5	5686	proteasome (prosome, macropain) subunit, alpha type, 5	stimulatory C-type lectin receptor signaling pathway	Biological process	-
EDN3	1908	endothelin 3	positive regulation of potassium ion transmembrane transport	Biological process	-
EIF3E	3646	eukaryotic translation initiation factor 3, subunit E	poly(A) RNA binding	Molecular function	22681889
TMEM161A	54929	transmembrane protein 161A	positive regulation of DNA repair	Biological process	16551573
NCOA5	57727	nuclear receptor coactivator 5	extracellular space	Cellular component	22664934
RBPJ	3516	recombination signal binding protein for immunoglobulin kappa J region	nucleolus	Cellular component	9874765
CSNK1D	1453	casein kinase 1, delta	positive regulation of canonical Wnt signaling pathway	Biological process	20412773
HYAL2	8692	hyaluronoglucosaminidase 2	response to antibiotic	Biological process	11944887
XPO5	57510	exportin 5	protein transporter activity	Molecular function	-
EXOSC5	56915	exosome component 5	cytoplasmic exosome (RNase complex)	Cellular component	-
APRT	353	adenine phosphoribosyltransferase	purine nucleobase metabolic process	Biological process	-
TTC8	123016	tetratricopeptide repeat domain 8	nonmotile primary cilium assembly	Biological process	-
DDR2	4921	discoidin domain receptor tyrosine kinase 2	biomineral tissue development	Biological process	-
ZNF197	10168	zinc finger protein 197	metal ion binding	Molecular function	-
ZSCAN2	54993	zinc finger and SCAN domain containing 2	regulation of transcription, DNA-templated	Biological process	-
BMP15	9210	bone morphogenetic protein 15	positive regulation of transcription, DNA-templated	Biological process	-
OR52N4	390072	olfactory receptor, family 52, subfamily N, member 4 (gene/pseudogene)	integral component of membrane	Cellular component	-
HTR1A	3350	5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled	regulation of hormone secretion	Biological process	-
CLCN3	1182	chloride channel, voltage-sensitive 3	PDZ domain binding	Molecular function	12471024
FMOD	2331	fibromodulin	extracellular matrix organization	Biological process	-
TTC26	79989	tetratricopeptide repeat domain 26	primary cilium	Cellular component	-
SMAD7	4092	SMAD family member 7	negative regulation of transcription by competitive promoter binding	Biological process	17438144
AR	367	androgen receptor	receptor binding	Molecular function	11875111
RGR	5995	retinal G protein coupled receptor	protein-chromophore linkage	Biological process	-
CRHR1	1394	corticotropin releasing hormone receptor 1	neuronal cell body	Cellular component	-
HHEX	3087	hematopoietically expressed homeobox	repressing transcription factor binding	Molecular function	15187083
BHMT	635	betaine--homocysteine S-methyltransferase	amino-acid betaine metabolic process	Biological process	18230605
SCMH1	22955	sex comb on midleg homolog 1 (Drosophila)	cellular protein metabolic process	Biological process	-
DNAH11	8701	dynein, axonemal, heavy chain 11	dynein complex	Cellular component	-
ARHGEF7	8874	Rho guanine nucleotide exchange factor (GEF) 7	guanyl-nucleotide exchange factor activity	Molecular function	21048939
CDKN2A	1029	cyclin-dependent kinase inhibitor 2A	senescence-associated heterochromatin focus	Cellular component	16901784
ROCK1	6093	Rho-associated, coiled-coil containing protein kinase 1	Rho protein signal transduction	Biological process	-
SPEF1	25876	sperm flagellar 1	molecular_function	Molecular function	-
DFFB	1677	DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)	cellular component disassembly involved in execution phase of apoptosis	Biological process	-
TRIM68	55128	tripartite motif containing 68	perinuclear region of cytoplasm	Cellular component	-
CLCN7	1186	chloride channel, voltage-sensitive 7	ion transmembrane transport	Biological process	-
BMPER	168667	BMP binding endothelial regulator	regulation of endothelial cell migration	Biological process	18787191
RASA1	5921	RAS p21 protein activator (GTPase activating protein) 1	glycoprotein binding	Molecular function	8618896
RPGR	6103	retinitis pigmentosa GTPase regulator	cilium assembly	Biological process	21933838
WNT4	54361	wingless-type MMTV integration site family, member 4	establishment of protein localization to plasma membrane	Biological process	17976063
EYA1	2138	EYA transcriptional coactivator and phosphatase 1	positive regulation of DNA repair	Biological process	19234442
LGR4	55366	leucine-rich repeat containing G protein-coupled receptor 4	innate immune response	Biological process	-
CRADD	8738	CASP2 and RIPK1 domain containing adaptor with death domain	activation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	-
C5AR1	728	complement component 5a receptor 1	response to lipopolysaccharide	Biological process	-
CCNB1	891	cyclin B1	regulation of chromosome condensation	Biological process	-
TEX2	55852	testis expressed 2	signal transduction	Biological process	16449791
ADGRE5	976	adhesion G protein-coupled receptor E5	focal adhesion	Cellular component	21423176
RHEB	6009	Ras homolog enriched in brain	transcription initiation from RNA polymerase II promoter	Biological process	-
LEF1	51176	lymphoid enhancer-binding factor 1	Wnt signaling pathway	Biological process	10644691
HHATL	57467	hedgehog acyltransferase-like	perinuclear region of cytoplasm	Cellular component	11374908
LRGUK	136332	leucine-rich repeats and guanylate kinase domain containing	kinase activity	Molecular function	-
GLRX2	51022	glutaredoxin 2	response to temperature stimulus	Biological process	11397793
KIRREL2	84063	kin of IRRE like 2 (Drosophila)	integral component of membrane	Cellular component	12837264
ATP4A	495	ATPase, H+/K+ exchanging, alpha polypeptide	extracellular space	Cellular component	22664934
NLRP1	22861	NLR family, pyrin domain containing 1	response to muramyl dipeptide	Biological process	-
ADIRF	10974	adipogenesis regulatory factor	cell differentiation	Biological process	-
JMY	133746	junction mediating and regulatory protein, p53 cofactor	actin binding	Molecular function	-
MRPL16	54948	mitochondrial ribosomal protein L16	mitochondrial translational elongation	Biological process	-
PKN2	5586	protein kinase N2	plasma membrane	Cellular component	-
GADD45B	4616	growth arrest and DNA-damage-inducible, beta	activation of MAPKK activity	Biological process	-
ITSN2	50618	intersectin 2	centrosome	Cellular component	20479469
FAM96B	51647	family with sequence similarity 96, member B	MMXD complex	Cellular component	20797633
SLC22A1	6580	solute carrier family 22 (organic cation transporter), member 1	plasma membrane	Cellular component	-
SOD1	6647	superoxide dismutase 1, soluble	dense core granule	Cellular component	-
SLC38A5	92745	solute carrier family 38, member 5	integral component of plasma membrane	Cellular component	-
OR9A1P	26495	olfactory receptor, family 9, subfamily A, member 1 pseudogene	G-protein coupled receptor activity	Molecular function	-
PPARG	5468	peroxisome proliferator-activated receptor gamma	epithelial cell differentiation	Biological process	-
FUT4	2526	fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)	protein glycosylation	Biological process	11698403
RAB3A	5864	RAB3A, member RAS oncogene family	response to electrical stimulus	Biological process	-
PPFIA2	8499	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2	synaptic transmission	Biological process	-
RNF135	84282	ring finger protein 135	ligase activity	Molecular function	-
PDE1C	5137	phosphodiesterase 1C, calmodulin-dependent 70kDa	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity	Molecular function	8557689
BCL10	8915	B-cell CLL/lymphoma 10	transcription factor binding	Molecular function	15207693
CD209	30835	CD209 molecule	cell surface	Cellular component	23981064
MRGBP	55257	MRG/MORF4L binding protein	chromatin organization	Biological process	-
POLR3C	10623	polymerase (RNA) III (DNA directed) polypeptide C (62kD)	positive regulation of innate immune response	Biological process	19609254
ATP1A2	477	ATPase, Na+/K+ transporting, alpha 2 polypeptide	locomotion	Biological process	-
ERN1	2081	endoplasmic reticulum to nucleus signaling 1	mRNA cleavage	Biological process	21317875
OR10J5	127385	olfactory receptor, family 10, subfamily J, member 5	plasma membrane	Cellular component	-
JAK2	3717	Janus kinase 2	histone kinase activity (H3-Y41 specific)	Molecular function	19783980
EDN1	1906	endothelin 1	prostaglandin biosynthetic process	Biological process	9492062
RAB34	83871	RAB34, member RAS oncogene family	antigen processing and presentation	Biological process	19717423
MAP10	54627	microtubule-associated protein 10	mitotic spindle midzone	Cellular component	23264731
SOX11	6664	SRY (sex determining region Y)-box 11	negative regulation of transcription regulatory region DNA binding	Biological process	-
UQCRQ	27089	ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa	mitochondrial inner membrane	Cellular component	-
ZNF641	121274	zinc finger protein 641	nucleus	Cellular component	-
ONECUT1	3175	one cut homeobox 1	glucose metabolic process	Biological process	-
COX4I1	1327	cytochrome c oxidase subunit IV isoform 1	cytochrome-c oxidase activity	Molecular function	-
IKZF5	64376	IKAROS family zinc finger 5 (Pegasus)	regulation of transcription, DNA-templated	Biological process	-
LRRC1	55227	leucine rich repeat containing 1	cytoplasm	Cellular component	-
CAPN3	825	calpain 3, (p94)	regulation of myoblast differentiation	Biological process	-
FGFR3	2261	fibroblast growth factor receptor 3	negative regulation of astrocyte differentiation	Biological process	-
CAMK1	8536	calcium/calmodulin-dependent protein kinase I	regulation of muscle cell differentiation	Biological process	11114197
GTPBP4	23560	GTP binding protein 4	poly(A) RNA binding	Molecular function	22658674
VEGFA	7422	vascular endothelial growth factor A	positive regulation of mesenchymal cell proliferation	Biological process	-
GAS6	2621	growth arrest-specific 6	endoplasmic reticulum lumen	Cellular component	-
SLC35C2	51006	solute carrier family 35 (GDP-fucose transporter), member C2	endoplasmic reticulum-Golgi intermediate compartment membrane	Cellular component	-
TLE2	7089	transducin-like enhancer of split 2	nucleoplasm	Cellular component	-
HS1BP3	64342	HCLS1 binding protein 3	phosphatidylinositol binding	Molecular function	-
ALDOC	230	aldolase C, fructose-bisphosphate	mitochondrion	Cellular component	-
PCDHGA10	56106	protocadherin gamma subfamily A, 10	integral component of membrane	Cellular component	-
AP5Z1	9907	adaptor-related protein complex 5, zeta 1 subunit	endosomal transport	Biological process	22022230
PCM1	5108	pericentriolar material 1	mitotic cell cycle	Biological process	-
CHRM1	1128	cholinergic receptor, muscarinic 1	cell junction	Cellular component	-
MLST8	64223	MTOR associated protein, LST8 homolog (S. cerevisiae)	cytoplasm	Cellular component	-
B2M	567	beta-2-microglobulin	MHC class I protein complex	Cellular component	-
HIST1H4C	8364	histone cluster 1, H4c	protein complex	Cellular component	14718166
DEFB123	245936	defensin, beta 123	cell surface	Cellular component	-
FGF5	2250	fibroblast growth factor 5	fibroblast growth factor receptor signaling pathway	Biological process	-
HACD2	201562	3-hydroxyacyl-CoA dehydratase 2	endoplasmic reticulum	Cellular component	15024066
TOPAZ1	375337	testis and ovary specific PAZ domain containing 1	metal ion binding	Molecular function	-
P2RX4	5025	purinergic receptor P2X, ligand gated ion channel, 4	purinergic nucleotide receptor activity	Molecular function	11606481
GGT1	2678	gamma-glutamyltransferase 1	glutathione derivative biosynthetic process	Biological process	-
GTF2H3	2967	general transcription factor IIH, polypeptide 3, 34kDa	protein binding	Molecular function	25416956
GH1	2688	growth hormone 1	extracellular region	Cellular component	-
SUMO1	7341	small ubiquitin-like modifier 1	synapse	Cellular component	-
TPT1	7178	tumor protein, translationally-controlled 1	extracellular space	Cellular component	15319436
RARG	5916	retinoic acid receptor, gamma	prostate gland epithelium morphogenesis	Biological process	-
CCDC67	159989	coiled-coil domain containing 67	protein binding	Molecular function	16189514
PCNA	5111	proliferating cell nuclear antigen	identical protein binding	Molecular function	15805117
XBP1	7494	X-box binding protein 1	positive regulation of ER-associated ubiquitin-dependent protein catabolic process	Biological process	22013210
FGF13	2258	fibroblast growth factor 13	MAPK cascade	Biological process	12244047
RPL22	6146	ribosomal protein L22	translational termination	Biological process	-
MIF	4282	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	positive regulation of peptidyl-serine phosphorylation	Biological process	17045821
AACS	65985	acetoacetyl-CoA synthetase	response to drug	Biological process	-
SLC25A53	401612	solute carrier family 25, member 53	mitochondrial inner membrane	Cellular component	-
THOC5	8563	THO complex 5	cytoplasm	Cellular component	-
OR2D3	120775	olfactory receptor, family 2, subfamily D, member 3	sensory perception of smell	Biological process	-
GLRX2	51022	glutaredoxin 2	glutathione metabolic process	Biological process	11397793
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	nucleoplasm	Cellular component	-
RIC8B	55188	RIC8 guanine nucleotide exchange factor B	cytosol	Cellular component	12652642
IGSF11	152404	immunoglobulin superfamily, member 11	integral component of membrane	Cellular component	-
LRP6	4040	low density lipoprotein receptor-related protein 6	frizzled binding	Molecular function	11029007
MNT	4335	MAX network transcriptional repressor	nucleus	Cellular component	-
CEP162	22832	centrosomal protein 162kDa	spindle	Cellular component	-
HCLS1	3059	hematopoietic cell-specific Lyn substrate 1	actin binding	Molecular function	-
CLCN7	1186	chloride channel, voltage-sensitive 7	lysosomal membrane	Cellular component	-
RPL26	6154	ribosomal protein L26	poly(A) RNA binding	Molecular function	22681889
STX3	6809	syntaxin 3	intracellular protein transport	Biological process	-
LRP2	4036	low density lipoprotein receptor-related protein 2	forebrain development	Biological process	-
GPER1	2852	G protein-coupled estrogen receptor 1	positive regulation of cell migration	Biological process	20551055
NCR2	9436	natural cytotoxicity triggering receptor 2	cellular defense response	Biological process	10049942
PELO	53918	pelota homolog (Drosophila)	chromosome organization	Biological process	-
RNF41	10193	ring finger protein 41, E3 ubiquitin protein ligase	positive regulation of reactive oxygen species metabolic process	Biological process	18541373
PGAP1	80055	post-GPI attachment to proteins 1	sensory perception of sound	Biological process	-
Sep-04	5414	septin 4	positive regulation of intrinsic apoptotic signaling pathway	Biological process	21185211
APEX2	27301	APEX nuclease (apurinic/apyrimidinic endonuclease) 2	double-stranded DNA 3'-5' exodeoxyribonuclease activity	Molecular function	-
EGFR	1956	epidermal growth factor receptor	phosphatidylinositol-mediated signaling	Biological process	-
PRAF2	11230	PRA1 domain family, member 2	integral component of membrane	Cellular component	-
PRIMA1	145270	proline rich membrane anchor 1	neurotransmitter catabolic process	Biological process	-
HIST1H3F	8968	histone cluster 1, H3f	nuclear nucleosome	Cellular component	20498094
ACVRL1	94	activin A receptor type II-like 1	signal transduction by protein phosphorylation	Biological process	-
TOP1MT	116447	topoisomerase (DNA) I, mitochondrial	DNA binding	Molecular function	-
PROK2	60675	prokineticin 2	cytosol	Cellular component	12728244
ZP3	7784	zona pellucida glycoprotein 3 (sperm receptor)	egg coat formation	Biological process	-
HEXB	3074	hexosaminidase B (beta polypeptide)	sensory perception of sound	Biological process	-
AP1S1	1174	adaptor-related protein complex 1, sigma 1 subunit	post-Golgi vesicle-mediated transport	Biological process	-
ATXN1	6310	ataxin 1	adult locomotory behavior	Biological process	-
SH3PXD2B	285590	SH3 and PX domains 2B	eye development	Biological process	20137777
OR10H5	284433	olfactory receptor, family 10, subfamily H, member 5	G-protein coupled receptor activity	Molecular function	-
JPH3	57338	junctophilin 3	exploration behavior	Biological process	-
RIMS4	140730	regulating synaptic membrane exocytosis 4	synaptic membrane	Cellular component	-
TSSK1B	83942	testis-specific serine kinase 1B	acrosomal vesicle	Cellular component	-
SOX4	6659	SRY (sex determining region Y)-box 4	neural tube formation	Biological process	-
IGLC7	28834	immunoglobulin lambda constant 7	complement activation	Biological process	-
NFE2L1	4779	nuclear factor, erythroid 2-like 1	sequence-specific DNA binding transcription factor activity	Molecular function	8248256
IRF4	3662	interferon regulatory factor 4	positive regulation of interleukin-10 biosynthetic process	Biological process	12374808
CMAS	55907	cytidine monophosphate N-acetylneuraminic acid synthetase	dolichol-linked oligosaccharide biosynthetic process	Biological process	-
CDC34	997	cell division cycle 34	negative regulation of cAMP-mediated signaling	Biological process	10373550
CYB5B	80777	cytochrome b5 type B (outer mitochondrial membrane)	integral component of membrane	Cellular component	-
CHD5	26038	chromodomain helicase DNA binding protein 5	membrane	Cellular component	19946888
LRP4	4038	low density lipoprotein receptor-related protein 4	proximal/distal pattern formation	Biological process	-
PNPLA7	375775	patatin-like phospholipase domain containing 7	nuclear membrane	Cellular component	-
WBP2	23558	WW domain binding protein 2	cellular response to estrogen stimulus	Biological process	23233354
SMAD4	4089	SMAD family member 4	negative regulation of protein catabolic process	Biological process	20097766
INO80E	283899	INO80 complex subunit E	nucleoplasm	Cellular component	-
HCLS1	3059	hematopoietic cell-specific Lyn substrate 1	regulation of transcription, DNA-templated	Biological process	2587259
EDNRB	1910	endothelin receptor type B	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
GRIA1	2890	glutamate receptor, ionotropic, AMPA 1	signal transduction	Biological process	1311100
KMT2E	55904	lysine (K)-specific methyltransferase 2E	neutrophil activation	Biological process	-
VPS26B	112936	vacuolar protein sorting 26 homolog B (S. pombe)	intracellular protein transport	Biological process	-
COL20A1	57642	collagen, type XX, alpha 1	collagen trimer	Cellular component	-
NLRP8	126205	NLR family, pyrin domain containing 8	cellular_component	Cellular component	-
B3GNT8	374907	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8	post-translational protein modification	Biological process	-
RAB7A	7879	RAB7A, member RAS oncogene family	melanosome	Cellular component	-
OAZ2	4947	ornithine decarboxylase antizyme 2	cellular nitrogen compound metabolic process	Biological process	-
GCM2	9247	glial cells missing homolog 2 (Drosophila)	cellular calcium ion homeostasis	Biological process	15728199
ABL1	25	ABL proto-oncogene 1, non-receptor tyrosine kinase	protein binding	Molecular function	11374898
DACT3	147906	dishevelled-binding antagonist of beta-catenin 3	Wnt signaling pathway	Biological process	-
RAD21	5885	RAD21 homolog (S. pombe)	cohesin complex	Cellular component	19468298
ADAM9	8754	ADAM metallopeptidase domain 9	protein kinase C binding	Molecular function	8647900
ZFYVE19	84936	zinc finger, FYVE domain containing 19	cleavage furrow	Cellular component	24814515
Sep-02	4735	septin 2	mitotic nuclear division	Biological process	-
FMO1	2326	flavin containing monooxygenase 1	monooxygenase activity	Molecular function	19262426
GBA2	57704	glucosidase, beta (bile acid) 2	central nervous system neuron development	Biological process	23332916
EPHB4	2050	EPH receptor B4	axon guidance	Biological process	-
AGO2	27161	argonaute RISC catalytic component 2	nucleoplasm	Cellular component	-
DKK1	22943	dickkopf WNT signaling pathway inhibitor 1	negative regulation of skeletal muscle tissue development	Biological process	-
SNX2	6643	sorting nexin 2	vesicle organization	Biological process	-
SNW1	22938	SNW domain containing 1	positive regulation of transforming growth factor beta receptor signaling pathway	Biological process	11278756
CYP1A2	1544	cytochrome P450, family 1, subfamily A, polypeptide 2	endoplasmic reticulum membrane	Cellular component	-
ADO	84890	2-aminoethanethiol (cysteamine) dioxygenase	mitochondrion	Cellular component	-
PRKACA	5566	protein kinase, cAMP-dependent, catalytic, alpha	AMP-activated protein kinase complex	Cellular component	21812984
SLC26A1	10861	solute carrier family 26 (anion exchanger), member 1	oxalate transmembrane transporter activity	Molecular function	-
HS3ST5	222537	heparan sulfate (glucosamine) 3-O-sulfotransferase 5	3'-phosphoadenosine 5'-phosphosulfate binding	Molecular function	12138164
USP45	85015	ubiquitin specific peptidase 45	protein deubiquitination	Biological process	14715245
FZD2	2535	frizzled class receptor 2	inner ear receptor cell development	Biological process	-
LRP1	4035	low density lipoprotein receptor-related protein 1	focal adhesion	Cellular component	21423176
INIP	58493	INTS3 and NABP interacting protein	DNA repair	Biological process	19605351
CASP3	836	caspase 3, apoptosis-related cysteine peptidase	neuron apoptotic process	Biological process	-
RPTN	126638	repetin	proteinaceous extracellular matrix	Cellular component	-
TBC1D15	64786	TBC1 domain family, member 15	cytoplasm	Cellular component	-
TXK	7294	TXK tyrosine kinase	T cell receptor signaling pathway	Biological process	-
PARK7	11315	parkinson protein 7	positive regulation of dopamine biosynthetic process	Biological process	19703902
CEBPB	1051	CCAAT/enhancer binding protein (C/EBP), beta	positive regulation of transcription from RNA polymerase II promoter	Biological process	7959007
NKX2-6	137814	NK2 homeobox 6	transcription, DNA-templated	Biological process	15649947
NDUFS7	374291	NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)	cellular metabolic process	Biological process	-
PYDC1	260434	PYD (pyrin domain) containing 1	tumor necrosis factor-mediated signaling pathway	Biological process	12656673
PRKD2	25865	protein kinase D2	peptidyl-serine phosphorylation	Biological process	18440775
ZFPM1	161882	zinc finger protein, FOG family member 1	negative regulation of protein binding	Biological process	-
ATP6V0D1	9114	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1	insulin receptor signaling pathway	Biological process	-
AANAT	15	aralkylamine N-acetyltransferase	cellular response to cAMP	Biological process	11313340
ATP6V1B1	525	ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1	sensory perception of sound	Biological process	19478356
TH	7054	tyrosine hydroxylase	anatomical structure morphogenesis	Biological process	7715703
PTK2	5747	protein tyrosine kinase 2	cell adhesion	Biological process	-
DEDD2	162989	death effector domain containing 2	RNA processing	Biological process	11741985
MOGS	7841	mannosyl-oligosaccharide glucosidase	mannosyl-oligosaccharide glucosidase activity	Molecular function	-
DLC1	10395	DLC1 Rho GTPase activating protein	neural tube closure	Biological process	-
MXI1	4601	MAX interactor 1, dimerization protein	negative regulation of cell proliferation	Biological process	9624006
FOXN1	8456	forkhead box N1	epithelial cell proliferation	Biological process	-
DNAH9	1770	dynein, axonemal, heavy chain 9	ATPase activity	Molecular function	-
CYP11B2	1585	cytochrome P450, family 11, subfamily B, polypeptide 2	xenobiotic metabolic process	Biological process	-
CST8	10047	cystatin 8 (cystatin-related epididymal specific)	negative regulation of endopeptidase activity	Biological process	1280328
MAFK	7975	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K	transcription, DNA-templated	Biological process	-
CASP16	197350	caspase 16, apoptosis-related cysteine peptidase (putative)	activation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	-
BAX	581	BCL2-associated X protein	Sertoli cell proliferation	Biological process	-
TAF7	6879	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa	transcription regulatory region DNA binding	Molecular function	18391197
AP2M1	1173	adaptor-related protein complex 2, mu 1 subunit	negative regulation of epidermal growth factor receptor signaling pathway	Biological process	-
SAP18	10284	Sin3A-associated protein, 18kDa	regulation of transcription from RNA polymerase II promoter	Biological process	9150135
KLF5	688	Kruppel-like factor 5 (intestinal)	cellular response to peptide	Biological process	-
PODXL	5420	podocalyxin-like	lamellipodium	Cellular component	18456258
ZC3H8	84524	zinc finger CCCH-type containing 8	positive regulation of transcription from RNA polymerase III promoter	Biological process	23932780
CXCL3	2921	chemokine (C-X-C motif) ligand 3	immune response	Biological process	-
VIMP	55829	VCP-interacting membrane selenoprotein	ER-associated ubiquitin-dependent protein catabolic process	Biological process	15215856
GPD1	2819	glycerol-3-phosphate dehydrogenase 1 (soluble)	NADH oxidation	Biological process	-
SFRP2	6423	secreted frizzled-related protein 2	positive regulation of catenin import into nucleus	Biological process	-
MAP2K7	5609	mitogen-activated protein kinase kinase 7	innate immune response	Biological process	-
F2RL3	9002	coagulation factor II (thrombin) receptor-like 3	blood coagulation	Biological process	-
DMBX1	127343	diencephalon/mesencephalon homeobox 1	brain development	Biological process	-
SOX7	83595	SRY (sex determining region Y)-box 7	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	19108950
CRH	1392	corticotropin releasing hormone	positive regulation of gene expression	Biological process	-
SLC39A8	64116	solute carrier family 39 (zinc transporter), member 8	transmembrane transport	Biological process	-
UPF1	5976	UPF1 regulator of nonsense transcripts homolog (yeast)	poly(A) RNA binding	Molecular function	22658674
NCAPG	64151	non-SMC condensin I complex, subunit G	mitotic chromosome condensation	Biological process	10910072
SMAD2	4087	SMAD family member 2	positive regulation of transcription, DNA-templated	Biological process	-
MTCL1	23255	microtubule crosslinking factor 1	microtubule bundle	Cellular component	-
NEUROD1	4760	neuronal differentiation 1	cellular response to glucose stimulus	Biological process	-
IL2	3558	interleukin 2	positive regulation of isotype switching to IgG isotypes	Biological process	-
GNB1	2782	guanine nucleotide binding protein (G protein), beta polypeptide 1	cellular response to prostaglandin E stimulus	Biological process	-
SPAG1	6674	sperm associated antigen 1	nucleoplasm	Cellular component	-
TAAR9	134860	trace amine associated receptor 9 (gene/pseudogene)	plasma membrane	Cellular component	-
NECAP1	25977	NECAP endocytosis associated 1	coated pit	Cellular component	-
CNIH3	149111	cornichon family AMPA receptor auxiliary protein 3	cell junction	Cellular component	-
TIMM23B	100652748	translocase of inner mitochondrial membrane 23 homolog B (yeast)	mitochondrial inner membrane presequence translocase complex	Cellular component	-
SLC38A7	55238	solute carrier family 38, member 7	L-asparagine transmembrane transporter activity	Molecular function	-
MAP4K2	5871	mitogen-activated protein kinase kinase kinase kinase 2	Golgi membrane	Cellular component	-
UBE2B	7320	ubiquitin-conjugating enzyme E2B	protein ubiquitination	Biological process	10373550
PDGFRB	5159	platelet-derived growth factor receptor, beta polypeptide	lysosomal lumen	Cellular component	-
ALDH9A1	223	aldehyde dehydrogenase 9 family, member A1	hormone metabolic process	Biological process	2925663
SGIP1	84251	SH3-domain GRB2-like (endophilin) interacting protein 1	response to dietary excess	Biological process	-
NRP1	8829	neuropilin 1	cellular response to hepatocyte growth factor stimulus	Biological process	21245381
SLC30A8	169026	solute carrier family 30 (zinc transporter), member 8	insulin secretion	Biological process	16984975
CHD7	55636	chromodomain helicase DNA binding protein 7	skeletal system development	Biological process	16155193
SRF	6722	serum response factor (c-fos serum response element-binding transcription factor)	neuron migration	Biological process	-
ARHGAP6	395	Rho GTPase activating protein 6	actin filament polymerization	Biological process	10699171
WDR11	55717	WD repeat domain 11	cytoplasm	Cellular component	-
SLC22A6	9356	solute carrier family 22 (organic anion transporter), member 6	organic anion transport	Biological process	22169006
SCX	642658	scleraxis basic helix-loop-helix transcription factor	negative regulation of transcription, DNA-templated	Biological process	-
BAX	581	BCL2-associated X protein	protein heterodimerization activity	Molecular function	9111042
CD40	958	CD40 molecule, TNF receptor superfamily member 5	protein binding	Molecular function	12140561
TDRD12	91646	tudor domain containing 12	fertilization	Biological process	-
ZNF654	55279	zinc finger protein 654	DNA binding	Molecular function	-
FABP6	2172	fatty acid binding protein 6, ileal	cytoplasm	Cellular component	7588781
FGF2	2247	fibroblast growth factor 2 (basic)	activation of MAPK activity	Biological process	9712850
ADGRL3	23284	adhesion G protein-coupled receptor L3	plasma membrane	Cellular component	-
AURKA	6790	aurora kinase A	centrosome	Cellular component	19774610
HIF1A	3091	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	signal transducer activity	Molecular function	-
SMAD5	4090	SMAD family member 5	ubiquitin protein ligase binding	Molecular function	11278251
SYBU	55638	syntabulin (syntaxin-interacting)	intracellular membrane-bounded organelle	Cellular component	-
NBN	4683	nibrin	isotype switching	Biological process	-
CLU	1191	clusterin	nucleus	Cellular component	-
MAK	4117	male germ cell-associated kinase	protein kinase activity	Molecular function	2183027
TEKT5	146279	tektin 5	microtubule	Cellular component	-
PSMB3	5691	proteasome (prosome, macropain) subunit, beta type, 3	nucleus	Cellular component	21630459
RELA	5970	v-rel avian reticuloendotheliosis viral oncogene homolog A	transcription factor complex	Cellular component	12048232
PSMD12	5718	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	nucleoplasm	Cellular component	-
MAD2L2	10459	MAD2 mitotic arrest deficient-like 2 (yeast)	regulation of cell growth	Biological process	15988022
ABCA3	21	ATP-binding cassette, sub-family A (ABC1), member 3	integral component of membrane	Cellular component	-
Mar-01	55016	membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase	plasma membrane	Cellular component	19117940
CCL5	6352	chemokine (C-C motif) ligand 5	positive regulation of homotypic cell-cell adhesion	Biological process	10488085
SSH2	85464	slingshot protein phosphatase 2	actin binding	Molecular function	11832213
SOX6	55553	SRY (sex determining region Y)-box 6	DNA binding	Molecular function	1614875
NXF2B	728343	nuclear RNA export factor 2B	mRNA export from nucleus	Biological process	11073998
ADAM19	8728	ADAM metallopeptidase domain 19	zinc ion binding	Molecular function	-
MYH9	4627	myosin, heavy chain 9, non-muscle	termination of G-protein coupled receptor signaling pathway	Biological process	-
ARHGAP39	80728	Rho GTPase activating protein 39	small GTPase mediated signal transduction	Biological process	-
B3GNT6	192134	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6	cellular protein metabolic process	Biological process	-
PSMB7	5695	proteasome (prosome, macropain) subunit, beta type, 7	regulation of cellular amino acid metabolic process	Biological process	-
STAT5B	6777	signal transducer and activator of transcription 5B	cellular response to epidermal growth factor stimulus	Biological process	-
ADORA2A	135	adenosine A2a receptor	activation of adenylate cyclase activity	Biological process	-
PHIP	55023	pleckstrin homology domain interacting protein	negative regulation of extrinsic apoptotic signaling pathway	Biological process	17636024
ITGB3	3690	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	platelet-derived growth factor receptor binding	Molecular function	19267251
PROM2	150696	prominin 2	extracellular exosome	Cellular component	19056867
CDC25B	994	cell division cycle 25B	protein kinase binding	Molecular function	12400006
ABL1	25	ABL proto-oncogene 1, non-receptor tyrosine kinase	nicotinate-nucleotide adenylyltransferase activity	Molecular function	20841568
VWF	7450	von Willebrand factor	platelet degranulation	Biological process	-
TSPAN15	23555	tetraspanin 15	tetraspanin-enriched microdomain	Cellular component	-
NR4A1	3164	nuclear receptor subfamily 4, group A, member 1	endothelial cell chemotaxis	Biological process	18059339
SFRP1	6422	secreted frizzled-related protein 1	cellular response to prostaglandin E stimulus	Biological process	16149501
GPRC5D	55507	G protein-coupled receptor, class C, group 5, member D	G-protein coupled receptor activity	Molecular function	-
PLD2	5338	phospholipase D2	protein binding	Molecular function	16407827
COL1A1	1277	collagen, type I, alpha 1	tooth mineralization	Biological process	17118335
HIST1H2BK	85236	histone cluster 1, H2bk	extracellular space	Cellular component	12860195
UMOD	7369	uromodulin	chemical homeostasis	Biological process	-
ARG1	383	arginase 1	regulation of L-arginine import	Biological process	-
SKP1	6500	S-phase kinase-associated protein 1	SCF ubiquitin ligase complex	Cellular component	15103331
CPNE6	9362	copine VI (neuronal)	calcium ion binding	Molecular function	9645480
UACA	55075	uveal autoantigen with coiled-coil domains and ankyrin repeats	negative regulation of NF-kappaB import into nucleus	Biological process	-
ZNF818P	390963	zinc finger protein 818, pseudogene	DNA binding	Molecular function	-
PSTPIP1	9051	proline-serine-threonine phosphatase interacting protein 1	uropod	Cellular component	-
CAPN12	147968	calpain 12	calcium-dependent cysteine-type endopeptidase activity	Molecular function	-
SRC	6714	SRC proto-oncogene, non-receptor tyrosine kinase	extrinsic component of cytoplasmic side of plasma membrane	Cellular component	-
SIN3A	25942	SIN3 transcription regulator family member A	small molecule metabolic process	Biological process	-
TRPV2	51393	transient receptor potential cation channel, subfamily V, member 2	cell body	Cellular component	-
MRGPRG	386746	MAS-related GPR, member G	integral component of plasma membrane	Cellular component	-
HTRA2	27429	HtrA serine peptidase 2	unfolded protein binding	Molecular function	10644717
TUBB1	81027	tubulin, beta 1 class VI	extracellular exosome	Cellular component	23533145
CDKN2D	1032	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	nucleus	Cellular component	15750620
SYT9	143425	synaptotagmin IX	plasma membrane	Cellular component	-
HERC5	51191	HECT and RLD domain containing E3 ubiquitin protein ligase 5	cytoplasm	Cellular component	-
MISP	126353	mitotic spindle positioning	cell cortex	Cellular component	-
HIST1H4E	8367	histone cluster 1, H4e	histone H4-K20 demethylation	Biological process	-
GPR183	1880	G protein-coupled receptor 183	positive regulation of B cell proliferation	Biological process	21673108
CPA2	1358	carboxypeptidase A2 (pancreatic)	carboxypeptidase activity	Molecular function	2920728
CYP26C1	340665	cytochrome P450, family 26, subfamily C, polypeptide 1	retinoic acid catabolic process	Biological process	14532297
OGG1	4968	8-oxoguanine DNA glycosylase	response to folic acid	Biological process	-
EPB41L3	23136	erythrocyte membrane protein band 4.1-like 3	cytoskeleton	Cellular component	-
CRABP1	1381	cellular retinoic acid binding protein 1	cytosol	Cellular component	-
BHLHE41	79365	basic helix-loop-helix family, member e41	nucleus	Cellular component	-
TBK1	29110	TANK-binding kinase 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	16127453
STOX1	219736	storkhead box 1	positive regulation of cyclin-dependent protein kinase activity	Biological process	22253775
CHMP3	51652	charged multivesicular body protein 3	ubiquitin-specific protease binding	Molecular function	18395747
NOS2	4843	nitric oxide synthase 2, inducible	perinuclear region of cytoplasm	Cellular component	-
PTEN	5728	phosphatase and tensin homolog	forebrain morphogenesis	Biological process	-
SETX	23064	senataxin	DNA helicase activity	Molecular function	17562789
CAPN10	11132	calpain 10	cell	Cellular component	17572128
MED1	5469	mediator complex subunit 1	androgen receptor signaling pathway	Biological process	12218053
EDN1	1906	endothelin 1	rough endoplasmic reticulum lumen	Cellular component	-
ADRB3	155	adrenoceptor beta 3	protein homodimerization activity	Molecular function	15123695
ZYX	7791	zyxin	cell-cell signaling	Biological process	8940160
FDXACB1	91893	ferredoxin-fold anticodon binding domain containing 1	protein binding	Molecular function	25416956
ADAM12	8038	ADAM metallopeptidase domain 12	zinc ion binding	Molecular function	-
MSH2	4436	mutS homolog 2	male gonad development	Biological process	-
GATA3	2625	GATA binding protein 3	ear development	Biological process	19248180
PARD6B	84612	par-6 family cell polarity regulator beta	extracellular exosome	Cellular component	19056867
PURB	5814	purine-rich element binding protein B	cell proliferation	Biological process	-
OR5L2	26338	olfactory receptor, family 5, subfamily L, member 2	olfactory receptor activity	Molecular function	-
CAMK1	8536	calcium/calmodulin-dependent protein kinase I	signal transduction	Biological process	-
CCSAP	126731	centriole, cilia and spindle-associated protein	centriole	Cellular component	22493317
FKBP4	2288	FK506 binding protein 4, 59kDa	tau protein binding	Molecular function	-
TMEM31	203562	transmembrane protein 31	integral component of membrane	Cellular component	-
MSX1	4487	msh homeobox 1	embryonic hindlimb morphogenesis	Biological process	-
TYROBP	7305	TYRO protein tyrosine kinase binding protein	cellular defense response	Biological process	9490415
C8orf44-SGK3	100533105	C8orf44-SGK3 readthrough	ATP binding	Molecular function	-
PGLYRP3	114771	peptidoglycan recognition protein 3	detection of bacterium	Biological process	11461926
TRIM22	10346	tripartite motif containing 22	Cajal body	Cellular component	-
SLC28A3	64078	solute carrier family 28 (concentrative nucleoside transporter), member 3	pyrimidine-containing compound transmembrane transport	Biological process	-
SOX2	6657	SRY (sex determining region Y)-box 2	neuron fate commitment	Biological process	-
CSGALNACT1	55790	chondroitin sulfate N-acetylgalactosaminyltransferase 1	Golgi cisterna membrane	Cellular component	-
PLCD4	84812	phospholipase C, delta 4	plasma membrane	Cellular component	-
PINX1	54984	PIN2/TERF1 interacting, telomerase inhibitor 1	kinetochore	Cellular component	19393617
MMP2	4313	matrix metallopeptidase 2	mitochondrion	Cellular component	-
KANSL2	54934	KAT8 regulatory NSL complex subunit 2	nucleoplasm	Cellular component	-
MAP3K1	4214	mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase	activation of protein kinase activity	Biological process	-
PDGFA	5154	platelet-derived growth factor alpha polypeptide	inner ear development	Biological process	-
STXBP1	6812	syntaxin binding protein 1	neuromuscular synaptic transmission	Biological process	-
XPA	7507	xeroderma pigmentosum, complementation group A	nucleus	Cellular component	-
TACC1	6867	transforming, acidic coiled-coil containing protein 1	regulation of microtubule-based process	Biological process	-
CXCL16	58191	chemokine (C-X-C motif) ligand 16	cellular response to lipopolysaccharide	Biological process	-
ZNF420	147923	zinc finger protein 420	metal ion binding	Molecular function	-
NPPC	4880	natriuretic peptide C	negative regulation of cell proliferation	Biological process	-
NUP37	79023	nucleoporin 37kDa	cytokine-mediated signaling pathway	Biological process	-
RYR2	6262	ryanodine receptor 2 (cardiac)	canonical Wnt signaling pathway	Biological process	-
GRID2	2895	glutamate receptor, ionotropic, delta 2	scaffold protein binding	Molecular function	-
RAB11FIP2	22841	RAB11 family interacting protein 2 (class I)	plasma membrane	Cellular component	-
MAMSTR	284358	MEF2 activating motif and SAP domain containing transcriptional regulator	transcription from RNA polymerase II promoter	Biological process	-
HIGD2B	123346	HIG1 hypoxia inducible domain family, member 2B	integral component of membrane	Cellular component	-
TSPAN10	83882	tetraspanin 10	establishment of protein localization to organelle	Biological process	23091066
MSX1	4487	msh homeobox 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
SNW1	22938	SNW domain containing 1	retinoic acid receptor binding	Molecular function	11514567
CSF3	1440	colony stimulating factor 3 (granulocyte)	positive regulation of cell proliferation	Biological process	-
ADPGK	83440	ADP-dependent glucokinase	extracellular region	Cellular component	-
DPYSL3	1809	dihydropyrimidinase-like 3	metabolic process	Biological process	-
FGD2	221472	FYVE, RhoGEF and PH domain containing 2	ruffle	Cellular component	-
NANOS3	342977	nanos homolog 3 (Drosophila)	oogenesis	Biological process	-
PDK3	5165	pyruvate dehydrogenase kinase, isozyme 3	pyruvate dehydrogenase (acetyl-transferring) kinase activity	Molecular function	11486000
LTK	4058	leukocyte receptor tyrosine kinase	transmembrane receptor protein tyrosine kinase activity	Molecular function	-
POLD1	5424	polymerase (DNA directed), delta 1, catalytic subunit	DNA-directed DNA polymerase activity	Molecular function	16762037
MRPL24	79590	mitochondrial ribosomal protein L24	ribosome	Cellular component	-
RPH3AL	9501	rabphilin 3A-like (without C2 domains)	Rab GTPase binding	Molecular function	-
H2AFX	3014	H2A histone family, member X	site of double-strand break	Cellular component	21270334
TUBB4A	10382	tubulin, beta 4A class IVa	protein folding	Biological process	-
TSPY2	64591	testis specific protein, Y-linked 2	nucleosome assembly	Biological process	-
DIAPH1	1729	diaphanous-related formin 1	ruffle membrane	Cellular component	-
SEMA5A	9037	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	signal clustering	Biological process	-
CHSY1	22856	chondroitin sulfate synthase 1	glycosaminoglycan metabolic process	Biological process	-
SYT9	143425	synaptotagmin IX	integral component of membrane	Cellular component	-
SMAD2	4087	SMAD family member 2	transforming growth factor beta receptor signaling pathway	Biological process	-
SIN3B	23309	SIN3 transcription regulator family member B	cytoplasm	Cellular component	-
MYF5	4617	myogenic factor 5	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity	Molecular function	2311584
KAT2A	2648	K(lysine) acetyltransferase 2A	chromatin remodeling	Biological process	8552087
PTK2B	2185	protein tyrosine kinase 2 beta	peptidyl-tyrosine autophosphorylation	Biological process	-
COL11A2	1302	collagen, type XI, alpha 2	skeletal system development	Biological process	7859284
FDX1L	112812	ferredoxin 1-like	C21-steroid hormone biosynthetic process	Biological process	-
FBXW9	84261	F-box and WD repeat domain containing 9	protein binding	Molecular function	19159283
CHCHD1	118487	coiled-coil-helix-coiled-coil-helix domain containing 1	nucleoplasm	Cellular component	-
CERS3	204219	ceramide synthase 3	sphingolipid biosynthetic process	Biological process	-
IL6ST	3572	interleukin 6 signal transducer	plasma membrane	Cellular component	-
NOL4L	140688	nucleolar protein 4-like	protein binding	Molecular function	25416956
PRKACA	5566	protein kinase, cAMP-dependent, catalytic, alpha	cAMP-dependent protein kinase complex	Cellular component	2843813
TTC39A	22996	tetratricopeptide repeat domain 39A	molecular_function	Molecular function	-
SFRP1	6422	secreted frizzled-related protein 1	cellular response to heparin	Biological process	17500071
KCNK13	56659	potassium channel, two pore domain subfamily K, member 13	potassium channel activity	Molecular function	-
PSMD2	5708	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
BPTF	2186	bromodomain PHD finger transcription factor	regulation of transcription, DNA-templated	Biological process	10575013
KDM5C	8242	lysine (K)-specific demethylase 5C	nucleoplasm	Cellular component	-
TREM1	54210	triggering receptor expressed on myeloid cells 1	neutrophil extravasation	Biological process	-
CBR3	874	carbonyl reductase 3	extracellular space	Cellular component	22664934
MAPRE1	22919	microtubule-associated protein, RP/EB family, member 1	G2/M transition of mitotic cell cycle	Biological process	-
GRXCR1	389207	glutaredoxin, cysteine rich 1	cell redox homeostasis	Biological process	-
MRPL2	51069	mitochondrial ribosomal protein L2	poly(A) RNA binding	Molecular function	22658674
CXADR	1525	coxsackie virus and adenovirus receptor	cytoplasm	Cellular component	22003382
BCL11B	64919	B-cell CLL/lymphoma 11B (zinc finger protein)	negative regulation of cell proliferation	Biological process	-
LDLR	3949	low density lipoprotein receptor	clathrin heavy chain binding	Molecular function	12121421
PAF1	54623	Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)	positive regulation of transcription from RNA polymerase II promoter	Biological process	20178742
CCND1	595	cyclin D1	cell division	Biological process	-
ARPC3	10094	actin related protein 2/3 complex, subunit 3, 21kDa	actin filament binding	Molecular function	11741539
BMP5	653	bone morphogenetic protein 5	skeletal system development	Biological process	2263636
PNN	5411	pinin, desmosome associated protein	catalytic step 2 spliceosome	Cellular component	11991638
RRP8	23378	ribosomal RNA processing 8, methyltransferase, homolog (yeast)	nucleolus	Cellular component	-
NDUFA13	51079	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13	integral component of membrane	Cellular component	-
JUNB	3726	jun B proto-oncogene	osteoclast differentiation	Biological process	-
AMIGO1	57463	adhesion molecule with Ig-like domain 1	axonal fasciculation	Biological process	12629050
MSTN	2660	myostatin	negative regulation of skeletal muscle satellite cell proliferation	Biological process	-
VPS37A	137492	vacuolar protein sorting 37 homolog A (S. cerevisiae)	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	Biological process	21757351
UBE2N	7334	ubiquitin-conjugating enzyme E2N	nucleus	Cellular component	16129784
ZW10	9183	zw10 kinetochore protein	kinetochore microtubule	Cellular component	11146660
TBCA	6902	tubulin folding cofactor A	nucleolus	Cellular component	-
TNKS	8658	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase	protein binding	Molecular function	12768206
IRF3	3661	interferon regulatory factor 3	response to exogenous dsRNA	Biological process	-
ALOX15B	247	arachidonate 15-lipoxygenase, type B	oxidation-reduction process	Biological process	-
EIF4B	1975	eukaryotic translation initiation factor 4B	poly(A) RNA binding	Molecular function	22658674
PTRH2	51651	peptidyl-tRNA hydrolase 2	protein binding	Molecular function	15006356
CCND1	595	cyclin D1	mammary gland epithelial cell proliferation	Biological process	-
GAN	8139	gigaxonin	cytoplasm	Cellular component	19424503
PKDCC	91461	protein kinase domain containing, cytoplasmic	lung alveolus development	Biological process	-
DRD2	1813	dopamine receptor D2	associative learning	Biological process	-
FAU	2197	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed	translational elongation	Biological process	-
KIF12	113220	kinesin family member 12	ATPase activity	Molecular function	-
LAMTOR1	55004	late endosomal/lysosomal adaptor, MAPK and MTOR activator 1	positive regulation of TOR signaling	Biological process	20381137
NCS1	23413	neuronal calcium sensor 1	positive regulation of exocytosis	Biological process	-
OR4M1	441670	olfactory receptor, family 4, subfamily M, member 1	transmembrane signaling receptor activity	Molecular function	-
PLD6	201164	phospholipase D family, member 6	protein homodimerization activity	Molecular function	17028579
IGLC7	28834	immunoglobulin lambda constant 7	plasma membrane	Cellular component	-
PSMA3	5684	proteasome (prosome, macropain) subunit, alpha type, 3	innate immune response	Biological process	-
HSF1	3297	heat shock transcription factor 1	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding	Molecular function	10561509
IFNL1	282618	interferon, lambda 1	negative regulation of interleukin-5 production	Biological process	19346497
SMAD3	4088	SMAD family member 3	SMAD protein signal transduction	Biological process	-
OR2S2	56656	olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene)	integral component of membrane	Cellular component	14983052
MGAT4D	152586	MGAT4 family, member D	transferase activity, transferring hexosyl groups	Molecular function	-
HLA-G	3135	major histocompatibility complex, class I, G	interferon-gamma-mediated signaling pathway	Biological process	-
CLCN3	1182	chloride channel, voltage-sensitive 3	regulation of pH	Biological process	12471024
CSPG5	10675	chondroitin sulfate proteoglycan 5 (neuroglycan C)	lysosomal lumen	Cellular component	-
LMBRD2	92255	LMBR1 domain containing 2	membrane	Cellular component	19946888
ABCC9	10060	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	synaptic transmission	Biological process	-
SLC35D3	340146	solute carrier family 35, member D3	anion transmembrane transport	Biological process	-
HHIP	64399	hedgehog interacting protein	integral component of plasma membrane	Cellular component	11435703
RSPH9	221421	radial spoke head 9 homolog (Chlamydomonas)	motile cilium	Cellular component	19200523
HOXD11	3237	homeobox D11	branching involved in ureteric bud morphogenesis	Biological process	-
RAB5A	5868	RAB5A, member RAS oncogene family	membrane raft	Cellular component	-
NAPA	8775	N-ethylmaleimide-sensitive factor attachment protein, alpha	regulation of synaptic vesicle priming	Biological process	-
BMS1	9790	BMS1 ribosome biogenesis factor	nucleus	Cellular component	-
TMEM127	55654	transmembrane protein 127	integral component of membrane	Cellular component	-
ACPP	55	acid phosphatase, prostate	integral component of membrane	Cellular component	-
RFX6	222546	regulatory factor X, 6	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	-
HLA-A	3105	major histocompatibility complex, class I, A	type I interferon signaling pathway	Biological process	-
CD44	960	CD44 molecule (Indian blood group)	Golgi apparatus	Cellular component	-
NUDT1	4521	nudix (nucleoside diphosphate linked moiety X)-type motif 1	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity	Molecular function	10373420
HIF1A	3091	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	RNA polymerase II transcription factor complex	Cellular component	7539918
FMNL1	752	formin-like 1	actin filament binding	Molecular function	-
TGFBR2	7048	transforming growth factor, beta receptor II (70/80kDa)	positive regulation of smooth muscle cell proliferation	Biological process	-
FURIN	5045	furin (paired basic amino acid cleaving enzyme)	extracellular matrix disassembly	Biological process	-
NEURL1	9148	neuralized E3 ubiquitin protein ligase 1	positive regulation of apoptotic process	Biological process	20847082
CDC42EP1	11135	CDC42 effector protein (Rho GTPase binding) 1	regulation of cell shape	Biological process	11035016
RNLS	55328	renalase, FAD-dependent amine oxidase	regulation of systemic arterial blood pressure	Biological process	-
CDH1	999	cadherin 1, type 1, E-cadherin (epithelial)	homophilic cell adhesion via plasma membrane adhesion molecules	Biological process	16338932
IDE	3416	insulin-degrading enzyme	bradykinin catabolic process	Biological process	17613531
SERPINE1	5054	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	defense response to Gram-negative bacterium	Biological process	17032919
QSOX1	5768	quiescin Q6 sulfhydryl oxidase 1	Golgi apparatus	Cellular component	-
FXYD7	53822	FXYD domain containing ion transport regulator 7	regulation of sodium ion transmembrane transporter activity	Biological process	-
AP3D1	8943	adaptor-related protein complex 3, delta 1 subunit	antigen processing and presentation, exogenous lipid antigen via MHC class Ib	Biological process	-
OXA1L	5018	oxidase (cytochrome c) assembly 1-like	protein binding	Molecular function	20601428
KCTD12	115207	potassium channel tetramerization domain containing 12	protein homooligomerization	Biological process	-
KRT8	3856	keratin 8, type II	intermediate filament	Cellular component	10852826
UBE2V2	7336	ubiquitin-conjugating enzyme E2 variant 2	protein polyubiquitination	Biological process	10089880
IRF3	3661	interferon regulatory factor 3	positive regulation of interferon-alpha production	Biological process	-
EEF1A2	1917	eukaryotic translation elongation factor 1 alpha 2	positive regulation of lipid kinase activity	Biological process	17088255
TOB2	10766	transducer of ERBB2, 2	positive regulation of ossification	Biological process	-
UNC93B1	81622	unc-93 homolog B1 (C. elegans)	endoplasmic reticulum	Cellular component	18082565
FLOT1	10211	flotillin 1	membrane raft	Cellular component	15469992
CCT6A	908	chaperonin containing TCP1, subunit 6A (zeta 1)	chaperonin-containing T-complex	Cellular component	23011926
HPSE	10855	heparanase	nucleoplasm	Cellular component	-
REG3G	130120	regenerating islet-derived 3 gamma	defense response to Gram-positive bacterium	Biological process	-
SHC1	6464	SHC (Src homology 2 domain containing) transforming protein 1	epidermal growth factor receptor signaling pathway	Biological process	-
ZNF253	56242	zinc finger protein 253	nucleus	Cellular component	-
MECP2	4204	methyl CpG binding protein 2	regulation of excitatory postsynaptic membrane potential	Biological process	-
KLF15	28999	Kruppel-like factor 15	positive regulation of transcription from RNA polymerase II promoter	Biological process	19767294
PIGS	94005	phosphatidylinositol glycan anchor biosynthesis, class S	post-translational protein modification	Biological process	-
EPHA2	1969	EPH receptor A2	regulation of angiogenesis	Biological process	-
CLEC3B	7123	C-type lectin domain family 3, member B	cytoplasm	Cellular component	15848710
TCF15	6939	transcription factor 15 (basic helix-loop-helix)	post-anal tail morphogenesis	Biological process	-
BIRC2	329	baculoviral IAP repeat containing 2	regulation of necrotic cell death	Biological process	-
BCHE	590	butyrylcholinesterase	catalytic activity	Molecular function	11569538
MED1	5469	mediator complex subunit 1	positive regulation of keratinocyte differentiation	Biological process	17082781
CLOCK	9575	clock circadian regulator	regulation of transcription, DNA-templated	Biological process	-
GBA	2629	glucosidase, beta, acid	carbohydrate metabolic process	Biological process	-
IL2RB	3560	interleukin 2 receptor, beta	external side of plasma membrane	Cellular component	-
MAN1A1	4121	mannosidase, alpha, class 1A, member 1	cellular protein metabolic process	Biological process	-
ADAM17	6868	ADAM metallopeptidase domain 17	metalloendopeptidase activity	Molecular function	-
GLYATL1	92292	glycine-N-acyltransferase-like 1	metabolic process	Biological process	-
CPSF3	51692	cleavage and polyadenylation specific factor 3, 73kDa	mRNA polyadenylation	Biological process	8929409
TLR9	54106	toll-like receptor 9	positive regulation of interferon-gamma biosynthetic process	Biological process	16286015
PTGS2	5743	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	angiogenesis	Biological process	-
KAT2B	8850	K(lysine) acetyltransferase 2B	nucleus	Cellular component	-
SLC22A1	6580	solute carrier family 22 (organic cation transporter), member 1	dopamine transmembrane transporter activity	Molecular function	-
PSMA6	5687	proteasome (prosome, macropain) subunit, alpha type, 6	G1/S transition of mitotic cell cycle	Biological process	-
RGL4	266747	ral guanine nucleotide dissociation stimulator-like 4	small GTPase mediated signal transduction	Biological process	-
AMER3	205147	APC membrane recruitment protein 3	Wnt signaling pathway	Biological process	-
E4F1	1877	E4F transcription factor 1	negative regulation of transcription from RNA polymerase II promoter	Biological process	14645522
MIXL1	83881	Mix paired-like homeobox	negative regulation of hematopoietic progenitor cell differentiation	Biological process	-
OSM	5008	oncostatin M	tyrosine phosphorylation of Stat3 protein	Biological process	-
FAM32A	26017	family with sequence similarity 32, member A	poly(A) RNA binding	Molecular function	22658674
ARID1A	8289	AT rich interactive domain 1A (SWI-like)	positive regulation of transcription, DNA-templated	Biological process	12200431
TUBG1	7283	tubulin, gamma 1	microtubule cytoskeleton organization	Biological process	1904010
JUN	3725	jun proto-oncogene	positive regulation of transcription from RNA polymerase II promoter	Biological process	2833704
CORO1B	57175	coronin, actin binding protein, 1B	actin filament bundle assembly	Biological process	17456547
ENG	2022	endoglin	positive regulation of transcription from RNA polymerase II promoter	Biological process	18974388
E2F1	1869	E2F transcription factor 1	negative regulation of transcription, DNA-templated	Biological process	20224733
CHST11	50515	carbohydrate (chondroitin 4) sulfotransferase 11	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity	Molecular function	-
CABP4	57010	calcium binding protein 4	calcium ion binding	Molecular function	15452577
HECA	51696	headcase homolog (Drosophila)	membrane	Cellular component	19946888
SPRED1	161742	sprouty-related, EVH1 domain containing 1	phosphatase binding	Molecular function	19389623
GRM7	2917	glutamate receptor, metabotropic 7	integral component of plasma membrane	Cellular component	9473604
LTBP1	4052	latent transforming growth factor beta binding protein 1	protein binding	Molecular function	12429738
CHTOP	26097	chromatin target of PRMT1	protein binding	Molecular function	14667819
SLC10A6	345274	solute carrier family 10 (sodium/bile acid cotransporter), member 6	bile acid:sodium symporter activity	Molecular function	-
IRG1	730249	immunoresponsive 1 homolog (mouse)	negative regulation of inflammatory response	Biological process	-
C22orf23	84645	chromosome 22 open reading frame 23	biological_process	Biological process	-
HIST1H4B	8366	histone cluster 1, H4b	mitotic cell cycle	Biological process	-
RAPGEF6	51735	Rap guanine nucleotide exchange factor (GEF) 6	protein localization to plasma membrane	Biological process	22797597
FURIN	5045	furin (paired basic amino acid cleaving enzyme)	negative regulation of endopeptidase activity	Biological process	10567353
SLC26A4	5172	solute carrier family 26 (anion exchanger), member 4	iodide transport	Biological process	-
CUL7	9820	cullin 7	regulation of mitotic nuclear division	Biological process	24793695
ANXA2	302	annexin A2	extracellular exosome	Cellular component	19056867
LEP	3952	leptin	central nervous system neuron development	Biological process	-
MAPRE3	22924	microtubule-associated protein, RP/EB family, member 3	microtubule cytoskeleton	Cellular component	10644998
CDC42	998	cell division cycle 42	axon guidance	Biological process	-
SRF	6722	serum response factor (c-fos serum response element-binding transcription factor)	heart trabecula formation	Biological process	-
IFI35	3430	interferon-induced protein 35	type I interferon signaling pathway	Biological process	-
NUP88	4927	nucleoporin 88kDa	mRNA transport	Biological process	-
AGXT	189	alanine-glyoxylate aminotransferase	small molecule metabolic process	Biological process	-
STX17	55014	syntaxin 17	endoplasmic reticulum-Golgi intermediate compartment	Cellular component	23006999
CAV3	859	caveolin 3	regulation of protein kinase B signaling	Biological process	-
PRMT2	3275	protein arginine methyltransferase 2	cytosol	Cellular component	17587566
TYRO3	7301	TYRO3 protein tyrosine kinase	negative regulation of innate immune response	Biological process	-
ADM	133	adrenomedullin	response to insulin	Biological process	-
GRB10	2887	growth factor receptor-bound protein 10	insulin receptor binding	Molecular function	-
GALC	2581	galactosylceramidase	lysosomal lumen	Cellular component	-
FADD	8772	Fas (TNFRSF6)-associated via death domain	T cell homeostasis	Biological process	-
GIT1	28964	G protein-coupled receptor kinase interacting ArfGAP 1	axon guidance	Biological process	-
GNPTAB	79158	N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits	nucleus	Cellular component	-
NOTCH3	4854	notch 3	negative regulation of neuron differentiation	Biological process	-
NOP56	10528	NOP56 ribonucleoprotein	membrane	Cellular component	19946888
CDK15	65061	cyclin-dependent kinase 15	protein binding	Molecular function	22939624
PRKCA	5578	protein kinase C, alpha	positive regulation of cell adhesion	Biological process	11909826
PAIP1	10605	poly(A) binding protein interacting protein 1	nuclear-transcribed mRNA poly(A) tail shortening	Biological process	-
PHLDA3	23612	pleckstrin homology-like domain, family A, member 3	extracellular exosome	Cellular component	23376485
LIG1	3978	ligase I, DNA, ATP-dependent	nucleus	Cellular component	8696349
KRT10	3858	keratin 10, type I	keratinocyte differentiation	Biological process	22170488
METRNL	284207	meteorin, glial cell differentiation regulator-like	positive regulation of energy homeostasis	Biological process	-
CCL3	6348	chemokine (C-C motif) ligand 3	neutrophil chemotaxis	Biological process	10706735
LMNA	4000	lamin A/C	regulation of protein localization to nucleus	Biological process	-
RAB3A	5864	RAB3A, member RAS oncogene family	intracellular protein transport	Biological process	-
NPM2	10361	nucleophosmin/nucleoplasmin 2	oocyte differentiation	Biological process	12714744
AK7	122481	adenylate kinase 7	inflammatory response to antigenic stimulus	Biological process	-
JAK2	3717	Janus kinase 2	positive regulation of cell differentiation	Biological process	-
TRPM7	54822	transient receptor potential cation channel, subfamily M, member 7	ruffle	Cellular component	-
VHL	7428	von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase	transcription factor binding	Molecular function	11641274
GAL3ST4	79690	galactose-3-O-sulfotransferase 4	Golgi cisterna membrane	Cellular component	-
COX15	1355	cytochrome c oxidase assembly homolog 15 (yeast)	small molecule metabolic process	Biological process	-
TACR1	6869	tachykinin receptor 1	response to heat	Biological process	-
CENPP	401541	centromere protein P	cytosol	Cellular component	-
CBX2	84733	chromobox homolog 2	PcG protein complex	Cellular component	21282530
CLVS1	157807	clavesin 1	phosphatidylinositol-3,5-bisphosphate binding	Molecular function	19651769
YARS2	51067	tyrosyl-tRNA synthetase 2, mitochondrial	gene expression	Biological process	-
ZFHX3	463	zinc finger homeobox 3	negative regulation of transcription, DNA-templated	Biological process	11312261
HDAC11	79885	histone deacetylase 11	NAD-dependent histone deacetylase activity (H3-K18 specific)	Molecular function	-
TMEM216	51259	transmembrane protein 216	integral component of membrane	Cellular component	-
FKBP1A	2280	FK506 binding protein 1A, 12kDa	signal transducer activity	Molecular function	12761501
RPL36	25873	ribosomal protein L36	translational elongation	Biological process	-
MPP5	64398	membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)	cytoplasm	Cellular component	-
BTRC	8945	beta-transducin repeat containing E3 ubiquitin protein ligase	ubiquitin-protein transferase activity	Molecular function	15448698
GLI2	2736	GLI family zinc finger 2	transcription, DNA-templated	Biological process	-
VHL	7428	von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase	mitochondrion	Cellular component	12169691
PTPRR	5801	protein tyrosine phosphatase, receptor type, R	negative regulation of epithelial cell migration	Biological process	21724833
STX2	2054	syntaxin 2	cornified envelope assembly	Biological process	22226963
OCLN	100506658	occludin	integral component of membrane	Cellular component	-
TMEM27	57393	transmembrane protein 27	positive regulation of insulin secretion involved in cellular response to glucose stimulus	Biological process	16330323
KRT82	3888	keratin 82, type II	structural constituent of epidermis	Molecular function	10692104
FGF5	2250	fibroblast growth factor 5	neurotrophin TRK receptor signaling pathway	Biological process	-
AKAP6	9472	A kinase (PRKA) anchor protein 6	negative regulation of cAMP biosynthetic process	Biological process	-
OPN5	221391	opsin 5	photoreceptor activity	Molecular function	-
HIST1H3D	8351	histone cluster 1, H3d	DNA replication-dependent nucleosome assembly	Biological process	14718166
SERPINB12	89777	serpin peptidase inhibitor, clade B (ovalbumin), member 12	hematopoietic progenitor cell differentiation	Biological process	-
DCDC2	51473	doublecortin domain containing 2	cytoplasm	Cellular component	21698230
GRIN1	2902	glutamate receptor, ionotropic, N-methyl D-aspartate 1	ion transmembrane transport	Biological process	-
NLGN1	22871	neuroligin 1	establishment of protein localization	Biological process	-
OR56A3	390083	olfactory receptor, family 56, subfamily A, member 3	olfactory receptor activity	Molecular function	-
SAXO1	158297	stabilizer of axonemal microtubules 1	sperm flagellum	Cellular component	25673876
AGAP2	116986	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	membrane	Cellular component	19946888
GATA5	140628	GATA binding protein 5	transcription regulatory region DNA binding	Molecular function	9566909
ENPP6	133121	ectonucleotide pyrophosphatase/phosphodiesterase 6	plasma membrane	Cellular component	15788404
TMEM222	84065	transmembrane protein 222	integral component of membrane	Cellular component	-
PLK2	10769	polo-like kinase 2	positive regulation of protein binding	Biological process	-
MAP2K4	6416	mitogen-activated protein kinase kinase 4	JNK cascade	Biological process	-
CAV1	857	caveolin 1, caveolae protein, 22kDa	negative regulation of BMP signaling pathway	Biological process	15657086
IP6K2	51447	inositol hexakisphosphate kinase 2	inositol-1,4,5-trisphosphate 3-kinase activity	Molecular function	-
GBA	2629	glucosidase, beta, acid	protein binding	Molecular function	24162852
GNAS	2778	GNAS complex locus	adenylate cyclase-activating dopamine receptor signaling pathway	Biological process	-
ADAMTS4	9507	ADAM metallopeptidase with thrombospondin type 1 motif, 4	proteinaceous extracellular matrix	Cellular component	-
KLHL23	151230	kelch-like family member 23	protein binding	Molecular function	25036637
IGHV2-70	28454	immunoglobulin heavy variable 2-70	Fc-gamma receptor signaling pathway involved in phagocytosis	Biological process	-
PSMB4	5692	proteasome (prosome, macropain) subunit, beta type, 4	regulation of apoptotic process	Biological process	-
HDAC6	10013	histone deacetylase 6	positive regulation of hydrogen peroxide-mediated programmed cell death	Biological process	18606987
BAX	581	BCL2-associated X protein	regulation of cell cycle	Biological process	-
S100A7	6278	S100 calcium binding protein A7	zinc ion binding	Molecular function	10026247
GDF10	2662	growth differentiation factor 10	regulation of MAPK cascade	Biological process	-
GTF3A	2971	general transcription factor IIIA	nucleoplasm	Cellular component	-
CAT	847	catalase	positive regulation of NF-kappaB transcription factor activity	Biological process	-
PTGFRN	5738	prostaglandin F2 receptor inhibitor	endoplasmic reticulum membrane	Cellular component	-
SERPINA7	6906	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7	extracellular region	Cellular component	14718574
FBXO45	200933	F-box protein 45	protein ubiquitination	Biological process	-
C10orf2	56652	chromosome 10 open reading frame 2	organelle organization	Biological process	-
CLCN3	1182	chloride channel, voltage-sensitive 3	ATP binding	Molecular function	-
MTCH1	23787	mitochondrial carrier 1	regulation of signal transduction	Biological process	10551805
GNAL	2774	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type	G-protein coupled receptor binding	Molecular function	-
CCK	885	cholecystokinin	positive regulation of cell proliferation	Biological process	-
APOE	348	apolipoprotein E	negative regulation of dendritic spine maintenance	Biological process	24328732
STAT3	6774	signal transducer and activator of transcription 3 (acute-phase response factor)	ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity	Molecular function	17324931
ZNF526	116115	zinc finger protein 526	transcription, DNA-templated	Biological process	-
JAK2	3717	Janus kinase 2	positive regulation of tyrosine phosphorylation of Stat5 protein	Biological process	-
CTSB	1508	cathepsin B	peptidase activity	Molecular function	7890620
COL16A1	1307	collagen, type XVI, alpha 1	endoplasmic reticulum lumen	Cellular component	-
ACTC1	70	actin, alpha, cardiac muscle 1	cardiac muscle contraction	Biological process	-
COL9A1	1297	collagen, type IX, alpha 1	metal ion binding	Molecular function	-
OR2T8	343172	olfactory receptor, family 2, subfamily T, member 8	integral component of membrane	Cellular component	-
SPATA6	54558	spermatogenesis associated 6	motile cilium assembly	Biological process	-
LRPAP1	4043	low density lipoprotein receptor-related protein associated protein 1	receptor-mediated endocytosis	Biological process	2229028
PAK7	57144	p21 protein (Cdc42/Rac)-activated kinase 7	cell proliferation	Biological process	20070256
PCBP2	5094	poly(rC) binding protein 2	ribonucleoprotein complex	Cellular component	-
CLIP1	6249	CAP-GLY domain containing linker protein 1	microtubule plus-end	Cellular component	12433698
KRT73	319101	keratin 73, type II	protein binding	Molecular function	25416956
TNFSF15	9966	tumor necrosis factor (ligand) superfamily, member 15	cytokine activity	Molecular function	-
SCGB3A1	92304	secretoglobin, family 3A, member 1	regulation of cell proliferation	Biological process	11481438
ANKRD42	338699	ankyrin repeat domain 42	positive regulation of cytokine production involved in inflammatory response	Biological process	-
ANO7	50636	anoctamin 7	integral component of membrane	Cellular component	-
HPS1	3257	Hermansky-Pudlak syndrome 1	secretion of lysosomal enzymes	Biological process	-
AGTR2	186	angiotensin II receptor, type 2	inflammatory response	Biological process	-
KRT87P	85349	keratin 87 pseudogene	extracellular space	Cellular component	23580065
MUTYH	4595	mutY homolog	depurination	Biological process	-
C8A	731	complement component 8, alpha polypeptide	membrane attack complex	Cellular component	12413696
PPP1CB	5500	protein phosphatase 1, catalytic subunit, beta isozyme	negative regulation of transforming growth factor beta receptor signaling pathway	Biological process	-
BHLHA15	168620	basic helix-loop-helix family, member a15	mitochondrial calcium ion transport	Biological process	-
TRERF1	55809	transcriptional regulating factor 1	sequence-specific DNA binding transcription factor activity	Molecular function	11349124
DMRTA2	63950	DMRT-like family A2	sequence-specific DNA binding transcription factor activity	Molecular function	-
SUV39H2	79723	suppressor of variegation 3-9 homolog 2 (Drosophila)	chromatin organization	Biological process	-
DCUN1D4	23142	DCN1, defective in cullin neddylation 1, domain containing 4	biological_process	Biological process	-
LMTK3	114783	lemur tyrosine kinase 3	ATP binding	Molecular function	-
CRB2	286204	crumbs family member 2	mesoderm formation	Biological process	-
ATAD1	84896	ATPase family, AAA domain containing 1	membrane	Cellular component	19946888
IK	3550	IK cytokine, down-regulator of HLA II	identical protein binding	Molecular function	22365833
MED16	10025	mediator complex subunit 16	transcription initiation from RNA polymerase II promoter	Biological process	-
XRCC3	7517	X-ray repair complementing defective repair in Chinese hamster cells 3	perinuclear region of cytoplasm	Cellular component	16215984
CAMP	820	cathelicidin antimicrobial peptide	cytosol	Cellular component	-
NRAS	4893	neuroblastoma RAS viral (v-ras) oncogene homolog	neurotrophin TRK receptor signaling pathway	Biological process	-
SOX17	64321	SRY (sex determining region Y)-box 17	negative regulation of mesodermal cell fate specification	Biological process	-
RCN3	57333	reticulocalbin 3, EF-hand calcium binding domain	endoplasmic reticulum lumen	Cellular component	-
RPL7	6129	ribosomal protein L7	structural constituent of ribosome	Molecular function	12962325
ZEB1	6935	zinc finger E-box binding homeobox 1	transcription factor binding	Molecular function	-
P2RX7	5027	purinergic receptor P2X, ligand gated ion channel, 7	response to lipopolysaccharide	Biological process	-
CHRNA7	1139	cholinergic receptor, nicotinic, alpha 7 (neuronal)	cell junction	Cellular component	-
GAS1	2619	growth arrest-specific 1	camera-type eye development	Biological process	-
CHCHD3	54927	coiled-coil-helix-coiled-coil-helix domain containing 3	nucleus	Cellular component	22567091
SYT3	84258	synaptotagmin III	calcium ion-dependent exocytosis	Biological process	-
BCL6	604	B-cell CLL/lymphoma 6	negative regulation of cell growth	Biological process	10490843
CCL13	6357	chemokine (C-C motif) ligand 13	inflammatory response	Biological process	-
TSPAN2	10100	tetraspanin 2	myelin sheath	Cellular component	-
BAIAP2L2	80115	BAI1-associated protein 2-like 2	nucleoplasm	Cellular component	-
TRNP1	388610	TMF1-regulated nuclear protein 1	nucleus	Cellular component	-
RSPO2	340419	R-spondin 2	bone mineralization	Biological process	-
NPSR1	387129	neuropeptide S receptor 1	neuropeptide receptor activity	Molecular function	16790440
FBXO31	79791	F-box protein 31	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation	Biological process	19412162
PIK3IP1	113791	phosphoinositide-3-kinase interacting protein 1	protein binding	Molecular function	25416956
TCF4	6925	transcription factor 4	positive regulation of neuron differentiation	Biological process	-
RNF151	146310	ring finger protein 151	zinc ion binding	Molecular function	-
DDX5	1655	DEAD (Asp-Glu-Ala-Asp) box helicase 5	mRNA splicing, via spliceosome	Biological process	11991638
AS3MT	57412	arsenite methyltransferase	toxin metabolic process	Biological process	-
PKN1	5585	protein kinase N1	midbody	Cellular component	17332740
STRA6	64220	stimulated by retinoic acid 6	protein complex	Cellular component	-
TRIM59	286827	tripartite motif containing 59	negative regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	22588174
DEPDC5	9681	DEP domain containing 5	lysosomal membrane	Cellular component	17897319
NME1	4830	NME/NM23 nucleoside diphosphate kinase 1	hippocampus development	Biological process	-
MNAT1	4331	MNAT CDK-activating kinase assembly factor 1	transcription elongation from RNA polymerase II promoter	Biological process	-
PIK3C3	5289	phosphatidylinositol 3-kinase, catalytic subunit type 3	membrane	Cellular component	19946888
SACM1L	22908	SAC1 suppressor of actin mutations 1-like (yeast)	phosphatidylinositol dephosphorylation	Biological process	-
MLH3	27030	mutL homolog 3	mismatch repair	Biological process	12095912
PPOX	5498	protoporphyrinogen oxidase	porphyrin-containing compound biosynthetic process	Biological process	7713909
HDHD2	84064	haloacid dehalogenase-like hydrolase domain containing 2	protein binding	Molecular function	25416956
NLGN2	57555	neuroligin 2	carboxylic ester hydrolase activity	Molecular function	-
MDFIC	29969	MyoD family inhibitor domain containing	Golgi apparatus	Cellular component	-
BCAR1	9564	breast cancer anti-estrogen resistance 1	regulation of cell growth	Biological process	11607844
CDH3	1001	cadherin 3, type 1, P-cadherin (placental)	single organismal cell-cell adhesion	Biological process	-
PRDX3	10935	peroxiredoxin 3	response to hydrogen peroxide	Biological process	17893648
TFAP2B	7021	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	sympathetic nervous system development	Biological process	-
NUP214	8021	nucleoporin 214kDa	viral transcription	Biological process	-
RAB19	401409	RAB19, member RAS oncogene family	GTPase activity	Molecular function	-
ATP6V0A1	535	ATPase, H+ transporting, lysosomal V0 subunit a1	plasma membrane	Cellular component	17360703
CA13	377677	carbonic anhydrase XIII	zinc ion binding	Molecular function	-
HEATR1	55127	HEAT repeat containing 1	protein binding	Molecular function	22190034
HSD11B2	3291	hydroxysteroid (11-beta) dehydrogenase 2	oxidation-reduction process	Biological process	-
GUCY1A2	2977	guanylate cyclase 1, soluble, alpha 2	heme binding	Molecular function	-
MOBP	4336	myelin-associated oligodendrocyte basic protein	protein binding	Molecular function	25416956
CHAF1A	10036	chromatin assembly factor 1, subunit A (p150)	chromo shadow domain binding	Molecular function	15882967
ITGA11	22801	integrin, alpha 11	metal ion binding	Molecular function	-
IHH	3549	indian hedgehog	positive regulation of T cell differentiation in thymus	Biological process	-
RAB11A	8766	RAB11A, member RAS oncogene family	vesicle-mediated transport	Biological process	17462998
HTRA1	5654	HtrA serine peptidase 1	proteolysis	Biological process	-
SNTB2	6645	syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)	actin binding	Molecular function	-
CELSR2	1952	cadherin, EGF LAG seven-pass G-type receptor 2	G-protein coupled receptor activity	Molecular function	10907856
TFF2	7032	trefoil factor 2	negative regulation of gastric acid secretion	Biological process	-
SLC9A3R1	9368	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1	renal phosphate ion absorption	Biological process	18784102
PRSS21	10942	protease, serine, 21 (testisin)	protein binding	Molecular function	20211623
IKBKAP	8518	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein	cytoplasm	Cellular component	-
LOC101060157	101060157	uncharacterized LOC101060157	extracellular space	Cellular component	22664934
DDX3X	1654	DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked	negative regulation of cell growth	Biological process	16818630
HINFP	25988	histone H4 transcription factor	histone binding	Molecular function	14585971
TFAP2C	7022	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	hair follicle development	Biological process	-
ZAK	51776	sterile alpha motif and leucine zipper containing kinase AZK	protein serine/threonine kinase activity	Molecular function	11836244
LUM	4060	lumican	carbohydrate metabolic process	Biological process	-
UBQLN1	29979	ubiquilin 1	polyubiquitin binding	Molecular function	15147878
KRAS	3845	Kirsten rat sarcoma viral oncogene homolog	small GTPase mediated signal transduction	Biological process	-
EMD	2010	emerin	cellular response to growth factor stimulus	Biological process	16858403
PCDHB12	56124	protocadherin beta 12	nervous system development	Biological process	10380929
CRTC1	23373	CREB regulated transcription coactivator 1	nucleus	Cellular component	14506290
NF1	4763	neurofibromin 1	dendrite	Cellular component	1550670
MCM8	84515	minichromosome maintenance complex component 8	male gamete generation	Biological process	-
PPARGC1A	10891	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	positive regulation of transcription, DNA-templated	Biological process	15572661
MCHR2	84539	melanin-concentrating hormone receptor 2	G-protein coupled receptor activity	Molecular function	-
PRPF6	24148	pre-mRNA processing factor 6	RNA splicing, via transesterification reactions	Biological process	10788320
CRHBP	1393	corticotropin releasing hormone binding protein	extracellular space	Cellular component	1846945
ITGA3	3675	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	integrin binding	Molecular function	-
PSMA5	5686	proteasome (prosome, macropain) subunit, alpha type, 5	cellular nitrogen compound metabolic process	Biological process	-
IDO1	3620	indoleamine 2,3-dioxygenase 1	cytosol	Cellular component	-
RASSF4	83937	Ras association (RalGDS/AF-6) domain family member 4	signal transduction	Biological process	-
SEZ6	124925	seizure related 6 homolog (mouse)	perinuclear region of cytoplasm	Cellular component	-
RAC1	5879	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	actin filament polymerization	Biological process	9312003
CDKN1C	1028	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	negative regulation of phosphorylation	Biological process	19170105
CNTN2	6900	contactin 2 (axonal)	regulation of neuronal synaptic plasticity	Biological process	-
GRK7	131890	G protein-coupled receptor kinase 7	protein autophosphorylation	Biological process	15946941
CLCN2	1181	chloride channel, voltage-sensitive 2	transmembrane transport	Biological process	-
NADSYN1	55191	NAD synthetase 1	ATP binding	Molecular function	-
IL17RA	23765	interleukin 17 receptor A	positive regulation of interleukin-23 production	Biological process	21145111
VASP	7408	vasodilator-stimulated phosphoprotein	focal adhesion	Cellular component	-
RPL36AL	6166	ribosomal protein L36a-like	structural constituent of ribosome	Molecular function	-
P2RX1	5023	purinergic receptor P2X, ligand gated ion channel, 1	protein heterooligomerization	Biological process	-
RFC3	5983	replication factor C (activator 1) 3, 38kDa	DNA clamp loader activity	Molecular function	9488738
NGF	4803	nerve growth factor (beta polypeptide)	response to glucocorticoid	Biological process	-
MAP2K4	6416	mitogen-activated protein kinase kinase 4	positive regulation of neuron apoptotic process	Biological process	-
STX8	9482	syntaxin 8	vesicle	Cellular component	18570918
SMAD4	4089	SMAD family member 4	regulation of transforming growth factor beta2 production	Biological process	12411310
XIRP1	165904	xin actin-binding repeat containing 1	fascia adherens	Cellular component	-
JAK2	3717	Janus kinase 2	tyrosine phosphorylation of Stat5 protein	Biological process	-
CNOT2	4848	CCR4-NOT transcription complex, subunit 2	cytoplasm	Cellular component	21299754
S100A4	6275	S100 calcium binding protein A4	perinuclear region of cytoplasm	Cellular component	15033494
PAK1	5058	p21 protein (Cdc42/Rac)-activated kinase 1	ATP binding	Molecular function	-
ARHGEF28	64283	Rho guanine nucleotide exchange factor (GEF) 28	positive regulation of GTPase activity	Biological process	-
FASTKD3	79072	FAST kinase domains 3	cellular respiration	Biological process	20869947
GPC3	2719	glypican 3	glycosaminoglycan catabolic process	Biological process	-
LRP5	4041	low density lipoprotein receptor-related protein 5	anatomical structure regression	Biological process	-
PDE4D	5144	phosphodiesterase 4D, cAMP-specific	multicellular organism growth	Biological process	-
SAMD9L	219285	sterile alpha motif domain containing 9-like	common myeloid progenitor cell proliferation	Biological process	-
OR52E5	390082	olfactory receptor, family 52, subfamily E, member 5	integral component of membrane	Cellular component	-
BAX	581	BCL2-associated X protein	protein oligomerization	Biological process	19074440
MPV17	4358	MpV17 mitochondrial inner membrane protein	glomerular basement membrane development	Biological process	-
ENY2	56943	enhancer of yellow 2 homolog (Drosophila)	transcription coactivator activity	Molecular function	18206972
IGKV4-1	28908	immunoglobulin kappa variable 4-1	complement activation	Biological process	-
FMN2	56776	formin 2	microvillus	Cellular component	-
NLGN4X	57502	neuroligin 4, X-linked	protein binding	Molecular function	11368788
OR2T35	403244	olfactory receptor, family 2, subfamily T, member 35	G-protein coupled receptor signaling pathway	Biological process	-
HSP90B1	7184	heat shock protein 90kDa beta (Grp94), member 1	regulation of phosphoprotein phosphatase activity	Biological process	19000834
NACC2	138151	NACC family member 2, BEN and BTB (POZ) domain containing	histone deacetylase activity	Molecular function	22926524
AXIN2	8313	axin 2	cellular protein localization	Biological process	17072303
ABTB2	25841	ankyrin repeat and BTB (POZ) domain containing 2	protein heterodimerization activity	Molecular function	-
CHPF2	54480	chondroitin polymerizing factor 2	integral component of membrane	Cellular component	-
MIF	4282	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	inflammatory response	Biological process	-
SSX4	6759	synovial sarcoma, X breakpoint 4	regulation of transcription, DNA-templated	Biological process	-
MYO16	23026	myosin XVI	motor activity	Molecular function	-
SLC37A3	84255	solute carrier family 37, member 3	transmembrane transport	Biological process	-
ICT1	3396	immature colon carcinoma transcript 1	mitochondrial translational termination	Biological process	-
ADCY10	55811	adenylate cyclase 10 (soluble)	basal part of cell	Cellular component	-
SOX10	6663	SRY (sex determining region Y)-box 10	in utero embryonic development	Biological process	-
MED15	51586	mediator complex subunit 15	cytoplasm	Cellular component	-
SMARCA4	6597	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	definitive erythrocyte differentiation	Biological process	-
CLSTN3	9746	calsyntenin 3	synaptic transmission, glutamatergic	Biological process	-
MKX	283078	mohawk homeobox	nucleus	Cellular component	-
SLC38A1	81539	solute carrier family 38, member 1	sodium:amino acid symporter activity	Molecular function	10891391
ETFA	2108	electron-transfer-flavoprotein, alpha polypeptide	extracellular exosome	Cellular component	23376485
FGF2	2247	fibroblast growth factor 2 (basic)	extracellular region	Cellular component	-
PEMT	10400	phosphatidylethanolamine N-methyltransferase	phosphatidyl-N-methylethanolamine N-methyltransferase activity	Molecular function	-
MAPKAPK3	7867	mitogen-activated protein kinase-activated protein kinase 3	protein serine/threonine kinase activity	Molecular function	15850461
MEX3C	51320	mex-3 RNA binding family member C	cytoplasm	Cellular component	-
DEFA6	1671	defensin, alpha 6, Paneth cell-specific	Golgi lumen	Cellular component	-
CHRNA1	1134	cholinergic receptor, nicotinic, alpha 1 (muscle)	neuromuscular junction	Cellular component	8872460
ZHX1	11244	zinc fingers and homeoboxes 1	negative regulation of transcription, DNA-templated	Biological process	12237128
MITF	4286	microphthalmia-associated transcription factor	osteoclast differentiation	Biological process	-
SLC7A5	8140	solute carrier family 7 (amino acid transporter light chain, L system), member 5	integral component of plasma membrane	Cellular component	-
DMRT1	1761	doublesex and mab-3 related transcription factor 1	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
ARF6	382	ADP-ribosylation factor 6	establishment of epithelial cell polarity	Biological process	-
ATP8A1	10396	ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1	chromaffin granule membrane	Cellular component	-
EPB41	2035	erythrocyte membrane protein band 4.1	actin cytoskeleton organization	Biological process	8434260
GLMP	112770	glycosylated lysosomal membrane protein	sequence-specific DNA binding transcription factor activity	Molecular function	18021396
SERPINA5	5104	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5	heparin binding	Molecular function	11120760
RIPPLY3	53820	ripply transcriptional repressor 3	nucleus	Cellular component	10814524
ATP2B4	493	ATPase, Ca++ transporting, plasma membrane 4	ion transmembrane transport	Biological process	-
HNRNPF	3185	heterogeneous nuclear ribonucleoprotein F	mRNA splicing, via spliceosome	Biological process	-
PAX9	5083	paired box 9	protein binding	Molecular function	12657635
PSMC3	5702	proteasome (prosome, macropain) 26S subunit, ATPase, 3	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	Biological process	-
CD4	920	CD4 molecule	entry into host cell	Biological process	-
ETV2	2116	ets variant 2	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
TRMT10A	93587	tRNA methyltransferase 10 homolog A (S. cerevisiae)	nucleus	Cellular component	24204302
HTR2B	3357	5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled	positive regulation of nitric-oxide synthase activity	Biological process	15625277
CYP1A2	1544	cytochrome P450, family 1, subfamily A, polypeptide 2	arachidonic acid metabolic process	Biological process	-
CHRNB2	1141	cholinergic receptor, nicotinic, beta 2 (neuronal)	memory	Biological process	15964197
FLT3LG	2323	fms-related tyrosine kinase 3 ligand	regulation of myeloid dendritic cell activation	Biological process	-
CD24	100133941	CD24 molecule	Wnt signaling pathway	Biological process	16532032
NLRC5	84166	NLR family, CARD domain containing 5	positive regulation of transcription from RNA polymerase II promoter	Biological process	20639463
FCGR1B	2210	Fc fragment of IgG, high affinity Ib, receptor (CD64)	early endosome membrane	Cellular component	-
DAB1	1600	Dab, reelin signal transducer, homolog 1 (Drosophila)	perinuclear region of cytoplasm	Cellular component	-
NRP1	8829	neuropilin 1	facial nerve structural organization	Biological process	-
NOD2	64127	nucleotide-binding oligomerization domain containing 2	toll-like receptor 4 signaling pathway	Biological process	-
UBA52	7311	ubiquitin A-52 residue ribosomal protein fusion product 1	innate immune response	Biological process	-
MUC5AC	4586	mucin 5AC, oligomeric mucus/gel-forming	protein O-linked glycosylation	Biological process	-
ZFP36L2	678	ZFP36 ring finger protein-like 2	negative regulation of stem cell differentiation	Biological process	-
HDAC1	3065	histone deacetylase 1	negative regulation of androgen receptor signaling pathway	Biological process	15919722
NCOA3	8202	nuclear receptor coactivator 3	nuclear chromatin	Cellular component	15831516
CLDN2	9075	claudin 2	protein binding	Molecular function	25416956
HIST1H3I	8354	histone cluster 1, H3i	negative regulation of gene expression, epigenetic	Biological process	-
KITLG	4254	KIT ligand	negative regulation of mast cell apoptotic process	Biological process	-
FGF9	2254	fibroblast growth factor 9	fibroblast growth factor receptor binding	Molecular function	-
RGS9	8787	regulator of G-protein signaling 9	regulation of G-protein coupled receptor protein signaling pathway	Biological process	9765512
TIMELESS	8914	timeless circadian clock	lung development	Biological process	-
KLHL2	11275	kelch-like family member 2	protein binding	Molecular function	21784977
RPTOR	57521	regulatory associated protein of MTOR, complex 1	protein binding	Molecular function	12150925
SKIL	6498	SKI-like proto-oncogene	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
WDR36	134430	WD repeat domain 36	Pwp2p-containing subcomplex of 90S preribosome	Cellular component	-
RPS27A	6233	ribosomal protein S27a	fibroblast growth factor receptor signaling pathway	Biological process	-
PDE1C	5137	phosphodiesterase 1C, calmodulin-dependent 70kDa	metabolic process	Biological process	8557689
CDK5RAP2	55755	CDK5 regulatory subunit associated protein 2	microtubule binding	Molecular function	14654843
FAM81B	153643	family with sequence similarity 81, member B	nucleus	Cellular component	21630459
RAF1	5894	Raf-1 proto-oncogene, serine/threonine kinase	activation of adenylate cyclase activity	Biological process	15385642
STX17	55014	syntaxin 17	rough endoplasmic reticulum	Cellular component	10930465
MYC	4609	v-myc avian myelocytomatosis viral oncogene homolog	nucleoplasm	Cellular component	-
PLCZ1	89869	phospholipase C, zeta 1	multicellular organismal development	Biological process	-
SGOL1	151648	shugoshin-like 1 (S. pombe)	attachment of spindle microtubules to kinetochore	Biological process	17621308
LGALS3	3958	lectin, galactoside-binding, soluble, 3	mRNA processing	Biological process	-
ZNF470	388566	zinc finger protein 470	metal ion binding	Molecular function	-
EEF1A1	1915	eukaryotic translation elongation factor 1 alpha 1	nucleus	Cellular component	12426392
HADHB	3032	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit	long-chain-enoyl-CoA hydratase activity	Molecular function	-
NANS	54187	N-acetylneuraminic acid synthase	extracellular exosome	Cellular component	23376485
ATG9A	79065	autophagy related 9A	protein localization to pre-autophagosomal structure	Biological process	-
RND1	27289	Rho family GTPase 1	negative regulation of cell adhesion	Biological process	9531558
STAT5B	6777	signal transducer and activator of transcription 5B	positive regulation of smooth muscle cell proliferation	Biological process	-
PLN	5350	phospholamban	protein homooligomerization	Biological process	-
VIP	7432	vasoactive intestinal peptide	extracellular region	Cellular component	-
PALM	5064	paralemmin	synapse maturation	Biological process	-
SNAPC3	6619	small nuclear RNA activating complex, polypeptide 3, 50kDa	protein binding	Molecular function	25416956
HSD11B1	3290	hydroxysteroid (11-beta) dehydrogenase 1	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity	Molecular function	-
WDSUB1	151525	WD repeat, sterile alpha motif and U-box domain containing 1	ubiquitin-protein transferase activity	Molecular function	-
ANAPC4	29945	anaphase promoting complex subunit 4	protein K11-linked ubiquitination	Biological process	18485873
AGFG1	3267	ArfGAP with FG repeats 1	acrosome assembly	Biological process	-
UBR3	130507	ubiquitin protein ligase E3 component n-recognin 3 (putative)	zinc ion binding	Molecular function	-
CCNB3	85417	cyclin B3	meiotic cell cycle	Biological process	-
HLA-DQB2	3120	major histocompatibility complex, class II, DQ beta 2	clathrin-coated endocytic vesicle membrane	Cellular component	-
KAT5	10524	K(lysine) acetyltransferase 5	metal ion binding	Molecular function	-
DDX39B	7919	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B	ATP binding	Molecular function	-
MT1E	4493	metallothionein 1E	cellular response to cadmium ion	Biological process	16827180
ARNTL	406	aryl hydrocarbon receptor nuclear translocator-like	transcription factor complex	Cellular component	9576906
OR52E5	390082	olfactory receptor, family 52, subfamily E, member 5	olfactory receptor activity	Molecular function	-
DDX28	55794	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28	RNA secondary structure unwinding	Biological process	-
TMEM237	65062	transmembrane protein 237	integral component of membrane	Cellular component	-
SPAG5	10615	sperm associated antigen 5	spindle pole	Cellular component	-
FGF17	8822	fibroblast growth factor 17	signal transduction	Biological process	9514906
DUOX1	53905	dual oxidase 1	cuticle development	Biological process	11514595
PSAP	5660	prosaposin	integral component of membrane	Cellular component	1454804
TICAM2	353376	toll-like receptor adaptor molecule 2	toll-like receptor signaling pathway	Biological process	-
APOA5	116519	apolipoprotein A-V	lipase binding	Molecular function	15178420
ARG1	383	arginase 1	protein homotrimerization	Biological process	-
HES5	388585	hes family bHLH transcription factor 5	forebrain radial glial cell differentiation	Biological process	-
RBX1	9978	ring-box 1, E3 ubiquitin protein ligase	protein neddylation	Biological process	19250909
MFSD11	79157	major facilitator superfamily domain containing 11	molecular_function	Molecular function	-
EXT2	2132	exostosin glycosyltransferase 2	transferase activity, transferring glycosyl groups	Molecular function	12907669
TYMP	1890	thymidine phosphorylase	platelet-derived growth factor receptor binding	Molecular function	2005900
NDNF	79625	neuron-derived neurotrophic factor	heparin binding	Molecular function	-
HIATL2	84278	hippocampus abundant transcript-like 2	transmembrane transport	Biological process	-
TIMELESS	8914	timeless circadian clock	protein binding	Molecular function	15798197
PRKCI	5584	protein kinase C, iota	bicellular tight junction	Cellular component	-
RAB14	51552	RAB14, member RAS oncogene family	plasma membrane	Cellular component	-
TSFM	10102	Ts translation elongation factor, mitochondrial	poly(A) RNA binding	Molecular function	22681889
STOML3	161003	stomatin (EPB72)-like 3	plasma membrane	Cellular component	-
TACC2	10579	transforming, acidic coiled-coil containing protein 2	nuclear hormone receptor binding	Molecular function	15207008
CCNK	8812	cyclin K	mitotic nuclear division	Biological process	-
COL1A1	1277	collagen, type I, alpha 1	Golgi apparatus	Cellular component	-
PKN3	29941	protein kinase N3	protein binding	Molecular function	11432776
TMC6	11322	transmembrane channel-like 6	extracellular exosome	Cellular component	20458337
SRC	6714	SRC proto-oncogene, non-receptor tyrosine kinase	oogenesis	Biological process	-
PIH1D3	139212	PIH1 domain containing 3	cytoplasm	Cellular component	-
RPP38	10557	ribonuclease P/MRP 38kDa subunit	RNA phosphodiester bond hydrolysis	Biological process	9630247
CXCL16	58191	chemokine (C-X-C motif) ligand 16	extracellular region	Cellular component	-
FBLIM1	54751	filamin binding LIM protein 1	stress fiber	Cellular component	18829455
POMC	5443	proopiomelanocortin	cell-cell signaling	Biological process	9620771
PPP2CA	5515	protein phosphatase 2, catalytic subunit, alpha isozyme	fibroblast growth factor receptor signaling pathway	Biological process	-
SMO	6608	smoothened, frizzled class receptor	skeletal muscle fiber development	Biological process	-
MCAM	4162	melanoma cell adhesion molecule	cell adhesion	Biological process	-
KDELC2	143888	KDEL (Lys-Asp-Glu-Leu) containing 2	biological_process	Biological process	-
SCN8A	6334	sodium channel, voltage gated, type VIII alpha subunit	myelination	Biological process	-
ZDHHC20	253832	zinc finger, DHHC-type containing 20	protein-cysteine S-palmitoyltransferase activity	Molecular function	-
ARHGAP44	9912	Rho GTPase activating protein 44	positive regulation of GTPase activity	Biological process	-
CDK6	1021	cyclin-dependent kinase 6	cyclin-dependent protein kinase holoenzyme complex	Cellular component	17420273
RAB33B	83452	RAB33B, member RAS oncogene family	Golgi membrane	Cellular component	-
CYP26C1	340665	cytochrome P450, family 26, subfamily C, polypeptide 1	organelle fusion	Biological process	-
NRSN2	80023	neurensin 2	neuronal cell body	Cellular component	-
NKX3-2	579	NK3 homeobox 2	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
SFTPC	6440	surfactant protein C	response to retinoic acid	Biological process	-
DAB2IP	153090	DAB2 interacting protein	mitogen-activated protein kinase kinase binding	Molecular function	17389591
CXADR	1525	coxsackie virus and adenovirus receptor	receptor binding	Molecular function	14978041
EBNA1BP2	10969	EBNA1 binding protein 2	nucleolus	Cellular component	-
ERBB2IP	55914	erbb2 interacting protein	protein targeting	Biological process	-
LRRC8C	84230	leucine rich repeat containing 8 family, member C	protein binding	Molecular function	24790029
UBE2D2	7322	ubiquitin-conjugating enzyme E2D 2	ATP binding	Molecular function	-
HDAC5	10014	histone deacetylase 5	transcription corepressor activity	Molecular function	-
TPSB2	64499	tryptase beta 2 (gene/pseudogene)	protein binding	Molecular function	14670919
KAZALD1	81621	Kazal-type serine peptidase inhibitor domain 1	regulation of cell growth	Biological process	-
MBD5	55777	methyl-CpG binding domain protein 5	chromocenter	Cellular component	20700456
GABRR3	200959	gamma-aminobutyric acid (GABA) A receptor, rho 3 (gene/pseudogene)	GABA-A receptor activity	Molecular function	10542332
SPRR1A	6698	small proline-rich protein 1A	cornified envelope	Cellular component	10908733
ALDH4A1	8659	aldehyde dehydrogenase 4 family, member A1	proline biosynthetic process	Biological process	-
ERBB4	2066	erb-b2 receptor tyrosine kinase 4	epidermal growth factor receptor binding	Molecular function	8617750
DDX20	11218	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20	regulation of steroid biosynthetic process	Biological process	-
DHFR	1719	dihydrofolate reductase	regulation of transcription involved in G1/S transition of mitotic cell cycle	Biological process	-
CABP5	56344	calcium binding protein 5	signal transduction	Biological process	10625670
CAV1	857	caveolin 1, caveolae protein, 22kDa	cellular response to hyperoxia	Biological process	21382479
ATP6AP1	537	ATPase, H+ transporting, lysosomal accessory protein 1	pH reduction	Biological process	-
CALR	811	calreticulin	cytosol	Cellular component	11149926
SEMA3A	10371	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	facial nerve structural organization	Biological process	-
PSME3	10197	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)	negative regulation of apoptotic process	Biological process	-
SFRP1	6422	secreted frizzled-related protein 1	cellular response to estradiol stimulus	Biological process	11932307
PCDHB3	56132	protocadherin beta 3	integral component of membrane	Cellular component	11322959
GNPNAT1	64841	glucosamine-phosphate N-acetyltransferase 1	glucosamine 6-phosphate N-acetyltransferase activity	Molecular function	-
CCR7	1236	chemokine (C-C motif) receptor 7	cellular response to cytokine stimulus	Biological process	11602640
NPAS3	64067	neuronal PAS domain protein 3	cytoplasm	Cellular component	-
DYNLRB2	83657	dynein, light chain, roadblock-type 2	primary cilium	Cellular component	-
KLHL22	84861	kelch-like family member 22	mitotic spindle assembly checkpoint	Biological process	23455478
CYB5R1	51706	cytochrome b5 reductase 1	cytochrome-b5 reductase activity, acting on NAD(P)H	Molecular function	-
TULP3	7289	tubby like protein 3	intraciliary transport particle A	Cellular component	20889716
AKR1B10	57016	aldo-keto reductase family 1, member B10 (aldose reductase)	daunorubicin metabolic process	Biological process	20837989
PRODH	5625	proline dehydrogenase (oxidase) 1	mitochondrial matrix	Cellular component	-
FN1	2335	fibronectin 1	apical plasma membrane	Cellular component	-
FSHR	2492	follicle stimulating hormone receptor	follicle-stimulating hormone receptor activity	Molecular function	-
PRKACA	5566	protein kinase, cAMP-dependent, catalytic, alpha	transmembrane transport	Biological process	-
IGHG2	3501	immunoglobulin heavy constant gamma 2 (G2m marker)	Fc-gamma receptor signaling pathway involved in phagocytosis	Biological process	-
KIF1BP	26128	KIF1 binding protein	kinesin binding	Molecular function	16225668
SLC11A1	6556	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1	defense response to bacterium	Biological process	-
CTNNA1	1495	catenin (cadherin-associated protein), alpha 1, 102kDa	axon regeneration	Biological process	-
SPZ1	84654	spermatogenic leucine zipper 1	sequence-specific DNA binding transcription factor activity	Molecular function	-
CLIP1	6249	CAP-GLY domain containing linker protein 1	positive regulation of microtubule polymerization	Biological process	15262990
SMARCA4	6597	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	hindbrain development	Biological process	-
SP3	6670	Sp3 transcription factor	lung development	Biological process	-
CREBRF	153222	CREB3 regulatory factor	regulation of transcription, DNA-templated	Biological process	-
BCL2L1	598	BCL2-like 1	regulation of mitochondrial membrane permeability	Biological process	9843949
QDPR	5860	quinoid dihydropteridine reductase	tetrahydrobiopterin biosynthetic process	Biological process	-
RFX4	5992	regulatory factor X, 4 (influences HLA class II expression)	cerebellar cortex morphogenesis	Biological process	-
TOP2A	7153	topoisomerase (DNA) II alpha 170kDa	ubiquitin binding	Molecular function	15965487
PELO	53918	pelota homolog (Drosophila)	nucleus	Cellular component	-
SSPN	8082	sarcospan	cell junction	Cellular component	-
ARPC4	10093	actin related protein 2/3 complex, subunit 4, 20kDa	enzyme binding	Molecular function	23921388
FOXO4	4303	forkhead box O4	cell cycle arrest	Biological process	10783894
SRGAP3	9901	SLIT-ROBO Rho GTPase activating protein 3	cytosol	Cellular component	-
NOG	9241	noggin	positive regulation of glomerulus development	Biological process	-
PDPR	55066	pyruvate dehydrogenase phosphatase regulatory subunit	oxidation-reduction process	Biological process	-
RCOR2	283248	REST corepressor 2	DNA binding	Molecular function	-
GRM7	2917	glutamate receptor, metabotropic 7	negative regulation of cAMP biosynthetic process	Biological process	9144652
NAPSA	9476	napsin A aspartic peptidase	extracellular space	Cellular component	18216060
ANO9	338440	anoctamin 9	ion transmembrane transport	Biological process	-
HIST1H2AD	3013	histone cluster 1, H2ad	extracellular exosome	Cellular component	20458337
TDGF1	6997	teratocarcinoma-derived growth factor 1	cellular response to tumor necrosis factor	Biological process	17720976
CEP290	80184	centrosomal protein 290kDa	centriolar satellite	Cellular component	22797915
NR6A1	2649	nuclear receptor subfamily 6, group A, member 1	ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity	Molecular function	9134503
PDIA3	2923	protein disulfide isomerase family A, member 3	melanosome	Cellular component	-
ST3GAL1	6482	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	protein O-linked glycosylation	Biological process	-
HDAC6	10013	histone deacetylase 6	regulation of gene expression, epigenetic	Biological process	24413532
TTN	7273	titin	protein binding	Molecular function	11101506
ETV6	2120	ets variant 6	hematopoietic stem cell proliferation	Biological process	25581430
TRPV1	7442	transient receptor potential cation channel, subfamily V, member 1	plasma membrane	Cellular component	-
TFRC	7037	transferrin receptor	poly(A) RNA binding	Molecular function	22658674
POU3F3	5455	POU class 3 homeobox 3	central nervous system development	Biological process	8703082
SLC30A1	7779	solute carrier family 30 (zinc transporter), member 1	in utero embryonic development	Biological process	-
WNT10B	7480	wingless-type MMTV integration site family, member 10B	myoblast differentiation involved in skeletal muscle regeneration	Biological process	-
CENPE	1062	centromere protein E, 312kDa	blood coagulation	Biological process	-
ITCH	83737	itchy E3 ubiquitin protein ligase	ligase activity	Molecular function	-
ANXA5	308	annexin A5	endothelial microparticle	Cellular component	-
SUSD6	9766	sushi domain containing 6	cellular response to DNA damage stimulus	Biological process	24652652
SRC	6714	SRC proto-oncogene, non-receptor tyrosine kinase	peptidyl-tyrosine autophosphorylation	Biological process	-
PSMB6	5694	proteasome (prosome, macropain) subunit, beta type, 6	endopeptidase activity	Molecular function	8066462
NUPL2	11097	nucleoporin like 2	mitotic cell cycle	Biological process	-
AKR7A2	8574	aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)	cytosol	Cellular component	-
NDRG2	57447	NDRG family member 2	regulation of platelet-derived growth factor production	Biological process	-
ICMT	23463	isoprenylcysteine carboxyl methyltransferase	cAMP response element binding protein binding	Molecular function	-
USP9X	8239	ubiquitin specific peptidase 9, X-linked	transcription, DNA-templated	Biological process	-
ABT1	29777	activator of basal transcription 1	DNA binding	Molecular function	-
SOAT2	8435	sterol O-acyltransferase 2	very-low-density lipoprotein particle assembly	Biological process	15308631
GNAS	2778	GNAS complex locus	trans-Golgi network membrane	Cellular component	7997272
KIAA0586	9786	KIAA0586	smoothened signaling pathway	Biological process	-
PIGL	9487	phosphatidylinositol glycan anchor biosynthesis, class L	GPI anchor biosynthetic process	Biological process	10085243
ITGB6	3694	integrin, beta 6	plasma membrane	Cellular component	-
CERS3	204219	ceramide synthase 3	sphingolipid metabolic process	Biological process	-
IRF9	10379	interferon regulatory factor 9	nucleoplasm	Cellular component	-
ADRB1	153	adrenoceptor beta 1	beta-adrenergic receptor activity	Molecular function	8892658
HOXC5	3222	homeobox C5	nucleoplasm	Cellular component	-
RPL36	25873	ribosomal protein L36	viral transcription	Biological process	-
CATSPER1	117144	cation channel, sperm associated 1	single fertilization	Biological process	-
TTPA	7274	tocopherol (alpha) transfer protein	response to pH	Biological process	-
HAUS6	54801	HAUS augmin-like complex, subunit 6	centrosome organization	Biological process	19427217
ALX1	8092	ALX homeobox 1	nucleoplasm	Cellular component	-
CYB5A	1528	cytochrome b5 type A (microsomal)	L-ascorbic acid metabolic process	Biological process	-
CHD3	1107	chromodomain helicase DNA binding protein 3	NuRD complex	Cellular component	17827154
WNT9A	7483	wingless-type MMTV integration site family, member 9A	cornea development in camera-type eye	Biological process	16258938
PCDHB14	56122	protocadherin beta 14	synaptic transmission	Biological process	12231349
CYP2B6	1555	cytochrome P450, family 2, subfamily B, polypeptide 6	exogenous drug catabolic process	Biological process	19029318
KDM1A	23028	lysine (K)-specific demethylase 1A	transcription factor binding	Molecular function	20833138
NF1	4763	neurofibromin 1	regulation of blood vessel endothelial cell migration	Biological process	17404841
C6orf106	64771	chromosome 6 open reading frame 106	cellular_component	Cellular component	-
SEC24B	10427	SEC24 family member B	antigen processing and presentation of peptide antigen via MHC class I	Biological process	-
MTTP	4547	microsomal triglyceride transfer protein	receptor complex	Cellular component	23382219
KANK1	23189	KN motif and ankyrin repeat domains 1	negative regulation of Rho protein signal transduction	Biological process	18458160
FGR	2268	FGR proto-oncogene, Src family tyrosine kinase	regulation of innate immune response	Biological process	-
TRGV3	6976	T cell receptor gamma variable 3	plasma membrane	Cellular component	3458221
RPLP0	6175	ribosomal protein, large, P0	cellular protein metabolic process	Biological process	-
CSNK1D	1453	casein kinase 1, delta	cytoplasm	Cellular component	-
FAM173B	134145	family with sequence similarity 173, member B	integral component of membrane	Cellular component	-
POLH	5429	polymerase (DNA directed), eta	damaged DNA binding	Molecular function	-
NLGN3	54413	neuroligin 3	regulation of long-term synaptic potentiation	Biological process	-
GALNT7	51809	polypeptide N-acetylgalactosaminyltransferase 7	carbohydrate metabolic process	Biological process	10544240
PSMD11	5717	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	innate immune response	Biological process	-
NRF1	4899	nuclear respiratory factor 1	generation of precursor metabolites and energy	Biological process	7629110
CYP2J2	1573	cytochrome P450, family 2, subfamily J, polypeptide 2	heme binding	Molecular function	-
ACSS1	84532	acyl-CoA synthetase short-chain family member 1	ethanol oxidation	Biological process	-
ABCC2	1244	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	ATP binding	Molecular function	-
LAMB3	3914	laminin, beta 3	extracellular matrix organization	Biological process	-
DICER1	23405	dicer 1, ribonuclease type III	siRNA binding	Molecular function	15973356
PARVG	64098	parvin, gamma	cell-matrix adhesion	Biological process	11171322
ZNF536	9745	zinc finger protein 536	metal ion binding	Molecular function	-
CELSR1	9620	cadherin, EGF LAG seven-pass G-type receptor 1	regulation of actin cytoskeleton organization	Biological process	-
LOXL2	4017	lysyl oxidase-like 2	collagen fibril organization	Biological process	21835952
ACOXL	55289	acyl-CoA oxidase-like	biological_process	Biological process	-
EDNRA	1909	endothelin receptor type A	response to lipopolysaccharide	Biological process	-
UBE2M	9040	ubiquitin-conjugating enzyme E2M	protein ubiquitination	Biological process	9694792
AKR1C3	8644	aldo-keto reductase family 1, member C3	androsterone dehydrogenase activity	Molecular function	16983398
ITGB3BP	23421	integrin beta 3 binding protein (beta3-endonexin)	nucleus	Cellular component	10490654
ZNF512B	57473	zinc finger protein 512B	DNA binding	Molecular function	-
TRIP6	7205	thyroid hormone receptor interactor 6	zinc ion binding	Molecular function	-
YEATS4	8089	YEATS domain containing 4	chromatin organization	Biological process	-
NPAS2	4862	neuronal PAS domain protein 2	transcription factor complex	Cellular component	9576906
GLT1D1	144423	glycosyltransferase 1 domain containing 1	extracellular region	Cellular component	-
PDCD4	27250	programmed cell death 4 (neoplastic transformation inhibitor)	apoptotic process	Biological process	12054647
LLGL1	3996	lethal giant larvae homolog 1 (Drosophila)	protein kinase binding	Molecular function	7542763
TOP1	7150	topoisomerase (DNA) I	cytoplasmic mRNA processing body	Cellular component	12878161
IGF2BP2	10644	insulin-like growth factor 2 mRNA binding protein 2	nucleus	Cellular component	15618018
SYNJ2BP	55333	synaptojanin 2 binding protein	mitochondrion	Cellular component	18845145
RASA1	5921	RAS p21 protein activator (GTPase activating protein) 1	negative regulation of cell adhesion	Biological process	8344248
DSCAM	1826	Down syndrome cell adhesion molecule	cell adhesion	Biological process	-
MICAL2	9645	microtubule associated monooxygenase, calponin and LIM domain containing 2	positive regulation of transcription via serum response element binding	Biological process	24440334
OR4N2	390429	olfactory receptor, family 4, subfamily N, member 2	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
HECTD4	283450	HECT domain containing E3 ubiquitin protein ligase 4	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	-
PLCXD3	345557	phosphatidylinositol-specific phospholipase C, X domain containing 3	signal transduction	Biological process	-
ZNF304	57343	zinc finger protein 304	regulation of transcription, DNA-templated	Biological process	-
PTRF	284119	polymerase I and transcript release factor	protein binding	Molecular function	17026959
CNN3	1266	calponin 3, acidic	cytoplasm	Cellular component	-
P2RX7	5027	purinergic receptor P2X, ligand gated ion channel, 7	extracellular ATP-gated cation channel activity	Molecular function	9038151
HIF1AN	55662	hypoxia inducible factor 1, alpha subunit inhibitor	cofactor binding	Molecular function	12446723
UHRF1	29128	ubiquitin-like with PHD and ring finger domains 1	hemi-methylated DNA-binding	Molecular function	17673620
FOXA2	3170	forkhead box A2	regulation of transcription from RNA polymerase II promoter	Biological process	12911579
ABL2	27	ABL proto-oncogene 2, non-receptor tyrosine kinase	platelet-derived growth factor receptor signaling pathway	Biological process	-
OR5H1	26341	olfactory receptor, family 5, subfamily H, member 1	G-protein coupled receptor activity	Molecular function	-
PAFAH1B1	5048	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	mitotic cell cycle	Biological process	-
KLF4	9314	Kruppel-like factor 4 (gut)	negative regulation of transcription, DNA-templated	Biological process	9422764
PLCH2	9651	phospholipase C, eta 2	lipid catabolic process	Biological process	-
NHP2	55651	NHP2 ribonucleoprotein	nucleolus	Cellular component	-
SMN2	6607	survival of motor neuron 2, centromeric	SMN complex	Cellular component	11283611
IRX5	10265	iroquois homeobox 5	sequence-specific DNA binding	Molecular function	-
TNFRSF8	943	tumor necrosis factor receptor superfamily, member 8	cellular response to mechanical stimulus	Biological process	19593445
LRRC17	10234	leucine rich repeat containing 17	extracellular space	Cellular component	-
KLHL22	84861	kelch-like family member 22	protein monoubiquitination	Biological process	23455478
RAB6A	5870	RAB6A, member RAS oncogene family	viral process	Biological process	-
STAG2	10735	stromal antigen 2	sister chromatid cohesion	Biological process	15917200
MAFA	389692	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A	nucleus	Cellular component	12368292
HOXA13	3209	homeobox A13	nucleoplasm	Cellular component	-
TOR1AIP2	163590	torsin A interacting protein 2	endoplasmic reticulum membrane	Cellular component	-
ANKRD27	84079	ankyrin repeat domain 27 (VPS9 domain)	GTPase activator activity	Molecular function	-
TYK2	7297	tyrosine kinase 2	growth hormone receptor binding	Molecular function	10502458
NEK8	284086	NIMA-related kinase 8	cytoskeleton	Cellular component	-
OR7A17	26333	olfactory receptor, family 7, subfamily A, member 17	olfactory receptor activity	Molecular function	-
TUBB	203068	tubulin, beta class I	spindle assembly	Biological process	-
NFX1	4799	nuclear transcription factor, X-box binding 1	transcription from RNA polymerase II promoter	Biological process	7964459
FAF1	11124	Fas (TNFRSF6) associated factor 1	regulation of cell adhesion	Biological process	-
MEF2C	4208	myocyte enhancer factor 2C	toll-like receptor 9 signaling pathway	Biological process	-
ARHGAP15	55843	Rho GTPase activating protein 15	regulation of cell shape	Biological process	12650940
PPARGC1A	10891	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	transcription factor binding	Molecular function	12588810
RPS27A	6233	ribosomal protein S27a	membrane	Cellular component	19946888
TNFSF10	8743	tumor necrosis factor (ligand) superfamily, member 10	tumor necrosis factor receptor binding	Molecular function	-
VNN3	55350	vanin 3	pantetheine hydrolase activity	Molecular function	11491533
AES	166	amino-terminal enhancer of split	skeletal system development	Biological process	-
FAM126A	84668	family with sequence similarity 126, member A	signal transducer activity	Molecular function	10910037
EEF2	1938	eukaryotic translation elongation factor 2	positive regulation of translation	Biological process	23184662
OLFML2A	169611	olfactomedin-like 2A	extracellular matrix	Cellular component	-
ZFP37	7539	ZFP37 zinc finger protein	zinc ion binding	Molecular function	9585434
PPP6R3	55291	protein phosphatase 6, regulatory subunit 3	cytoplasm	Cellular component	-
LILRB1	10859	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	MHC class I protein binding	Molecular function	17869268
RAPGEF2	9693	Rap guanine nucleotide exchange factor (GEF) 2	integral component of plasma membrane	Cellular component	10934204
CD200R1	131450	CD200 receptor 1	receptor complex	Cellular component	23382219
ZWILCH	55055	zwilch kinetochore protein	cell division	Biological process	-
DGAT2	84649	diacylglycerol O-acyltransferase 2	triglyceride biosynthetic process	Biological process	-
WRN	7486	Werner syndrome, RecQ helicase-like	four-way junction helicase activity	Molecular function	11433031
CDK8	1024	cyclin-dependent kinase 8	ATP binding	Molecular function	-
EBI3	10148	Epstein-Barr virus induced 3	humoral immune response	Biological process	8551575
SLC30A7	148867	solute carrier family 30 (zinc transporter), member 7	cation transmembrane transporter activity	Molecular function	-
RALGAPB	57148	Ral GTPase activating protein, beta subunit (non-catalytic)	regulation of exocyst localization	Biological process	-
OR4K17	390436	olfactory receptor, family 4, subfamily K, member 17	transmembrane signaling receptor activity	Molecular function	-
NR1D1	9572	nuclear receptor subfamily 1, group D, member 1	negative regulation of transcription, DNA-templated	Biological process	18006707
CDK5	1020	cyclin-dependent kinase 5	negative regulation of cell cycle	Biological process	-
PRKCB	5579	protein kinase C, beta	cytoplasm	Cellular component	15632189
NPLOC4	55666	nuclear protein localization 4 homolog (S. cerevisiae)	membrane fusion	Biological process	11574150
SFR1	119392	SWI5-dependent recombination repair 1	double-strand break repair via homologous recombination	Biological process	21252223
ADAM17	6868	ADAM metallopeptidase domain 17	positive regulation of epidermal growth factor-activated receptor activity	Biological process	17655843
SKI	6497	SKI proto-oncogene	centrosome	Cellular component	21600873
ERCC2	2068	excision repair cross-complementation group 2	UV protection	Biological process	2835663
SLC34A1	6569	solute carrier family 34 (type II sodium/phosphate cotransporter), member 1	ion transport	Biological process	-
ZC3H14	79882	zinc finger CCCH-type containing 14	protein binding	Molecular function	19273536
MIEF1	54471	mitochondrial elongation factor 1	integral component of membrane	Cellular component	-
ABLIM3	22885	actin binding LIM protein family, member 3	lamellipodium	Cellular component	22684256
SMPD1	6609	sphingomyelin phosphodiesterase 1, acid lysosomal	hydrolase activity, acting on glycosyl bonds	Molecular function	-
DPCD	25911	deleted in primary ciliary dyskinesia homolog (mouse)	lateral ventricle development	Biological process	-
DPP4	1803	dipeptidyl-peptidase 4	plasma membrane	Cellular component	16670267
FBXL3	26224	F-box and leucine-rich repeat protein 3	nucleus	Cellular component	-
NTRK1	4914	neurotrophic tyrosine kinase, receptor, type 1	positive regulation of angiogenesis	Biological process	15488758
DNAL4	10126	dynein, axonemal, light chain 4	microtubule-based process	Biological process	-
POLR2M	81488	polymerase (RNA) II (DNA directed) polypeptide M	nuclear envelope	Cellular component	-
STK24	8428	serine/threonine kinase 24	regulation of axon regeneration	Biological process	19855390
CYP1A1	1543	cytochrome P450, family 1, subfamily A, polypeptide 1	cell proliferation	Biological process	-
RAB4B	53916	RAB4B, member RAS oncogene family	GTP binding	Molecular function	-
MDP1	145553	magnesium-dependent phosphatase 1	protein tyrosine phosphatase activity	Molecular function	-
VEZT	55591	vezatin, adherens junctions transmembrane protein	plasma membrane	Cellular component	-
ARL2	402	ADP-ribosylation factor-like 2	extracellular exosome	Cellular component	23376485
ADORA2A	135	adenosine A2a receptor	alpha-actinin binding	Molecular function	-
LIX1	167410	Lix1 homolog (chicken)	cytoplasm	Cellular component	-
GALNT11	63917	polypeptide N-acetylgalactosaminyltransferase 11	Golgi membrane	Cellular component	-
SLC2A2	6514	solute carrier family 2 (facilitated glucose transporter), member 2	regulation of insulin secretion	Biological process	-
SORT1	6272	sortilin 1	myotube differentiation	Biological process	18258592
LPAR3	23566	lysophosphatidic acid receptor 3	cytosol	Cellular component	10488122
CRNN	49860	cornulin	response to heat	Biological process	11606197
BCL2L12	83596	BCL2-like 12 (proline rich)	p53 binding	Molecular function	-
ARPC5	10092	actin related protein 2/3 complex, subunit 5, 16kDa	Arp2/3 protein complex	Cellular component	11741539
VPS28	51160	vacuolar protein sorting 28 homolog (S. cerevisiae)	protein complex binding	Molecular function	-
ABCA12	26154	ATP-binding cassette, sub-family A (ABC1), member 12	phospholipid transporter activity	Molecular function	-
DUSP4	1846	dual specificity phosphatase 4	toll-like receptor 2 signaling pathway	Biological process	-
SMAD5	4090	SMAD family member 5	positive regulation of transcription, DNA-templated	Biological process	10708949
ST3GAL2	6483	ST3 beta-galactoside alpha-2,3-sialyltransferase 2	extracellular region	Cellular component	-
VPS25	84313	vacuolar protein sorting 25 homolog (S. cerevisiae)	cytoplasm	Cellular component	16973552
PHOSPHO1	162466	phosphatase, orphan 1	phosphatidylcholine biosynthetic process	Biological process	-
LIG3	3980	ligase III, DNA, ATP-dependent	nucleus	Cellular component	-
HYAL2	8692	hyaluronoglucosaminidase 2	hyaluronoglucuronidase activity	Molecular function	21699545
DNAJA3	9093	DnaJ (Hsp40) homolog, subfamily A, member 3	cytosol	Cellular component	16531398
PSEN2	5664	presenilin 2	dendritic shaft	Cellular component	-
FAM71C	196472	family with sequence similarity 71, member C	protein binding	Molecular function	16189514
CCDC62	84660	coiled-coil domain containing 62	nucleus	Cellular component	19126643
BBS7	55212	Bardet-Biedl syndrome 7	regulation of transcription from RNA polymerase II promoter	Biological process	22302990
SUN2	25777	Sad1 and UNC84 domain containing 2	nuclear envelope	Cellular component	10375507
OR5H15	403274	olfactory receptor, family 5, subfamily H, member 15	plasma membrane	Cellular component	-
MRPL12	6182	mitochondrial ribosomal protein L12	mitochondrion	Cellular component	-
RAP1A	5906	RAP1A, member of RAS oncogene family	positive regulation of protein kinase activity	Biological process	-
VARS	7407	valyl-tRNA synthetase	gene expression	Biological process	-
PRKCH	5583	protein kinase C, eta	metal ion binding	Molecular function	-
TSPYL2	64061	TSPY-like 2	cellular protein metabolic process	Biological process	-
NANOG	79923	Nanog homeobox	positive regulation of transcription from RNA polymerase II promoter	Biological process	20713518
MAPKAPK3	7867	mitogen-activated protein kinase-activated protein kinase 3	calmodulin binding	Molecular function	-
PBXIP1	57326	pre-B-cell leukemia homeobox interacting protein 1	microtubule	Cellular component	-
CCDC47	57003	coiled-coil domain containing 47	membrane	Cellular component	16210410
PRRX2	51450	paired related homeobox 2	inner ear morphogenesis	Biological process	-
ETV6	2120	ets variant 6	cell differentiation	Biological process	-
LIN7C	55327	lin-7 homolog C (C. elegans)	maintenance of epithelial cell apical/basal polarity	Biological process	-
SLC38A10	124565	solute carrier family 38, member 10	integral component of membrane	Cellular component	-
NPR2	4882	natriuretic peptide receptor 2	cGMP biosynthetic process	Biological process	1672777
HAUS4	54930	HAUS augmin-like complex, subunit 4	microtubule	Cellular component	-
HES1	3280	hes family bHLH transcription factor 1	auditory receptor cell fate determination	Biological process	-
FSTL3	10272	follistatin-like 3 (secreted glycoprotein)	male gonad development	Biological process	-
SLAMF1	6504	signaling lymphocytic activation molecule family member 1	phagocytic vesicle	Cellular component	-
RFX3	5991	regulatory factor X, 3 (influences HLA class II expression)	sequence-specific DNA binding transcription factor activity	Molecular function	8600444
DYNLRB2	83657	dynein, light chain, roadblock-type 2	metabolic process	Biological process	11750132
DSP	1832	desmoplakin	intercalated disc	Cellular component	22781308
LANCL2	55915	LanC lantibiotic synthetase component C-like 2 (bacterial)	phosphatidylinositol-4-phosphate binding	Molecular function	16979580
ARL6	84100	ADP-ribosylation factor-like 6	cytosol	Cellular component	-
SPC24	147841	SPC24, NDC80 kinetochore complex component	Ndc80 complex	Cellular component	14699129
TST	7263	thiosulfate sulfurtransferase (rhodanese)	sulfide oxidation, using sulfide:quinone oxidoreductase	Biological process	-
IL1RL1	9173	interleukin 1 receptor-like 1	interleukin-33 binding	Molecular function	-
ADAMTSL2	9719	ADAMTS-like 2	zinc ion binding	Molecular function	-
ELF1	1997	E74-like factor 1 (ets domain transcription factor)	protein binding	Molecular function	10207087
BCKDHA	593	branched chain keto acid dehydrogenase E1, alpha polypeptide	metal ion binding	Molecular function	-
IAH1	285148	isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)	extracellular exosome	Cellular component	23376485
KCNAB2	8514	potassium channel, voltage gated subfamily A regulatory beta subunit 2	extrinsic component of cytoplasmic side of plasma membrane	Cellular component	-
PLA2G15	23659	phospholipase A2, group XV	calcium-independent phospholipase A2 activity	Molecular function	-
SMPD4	55627	sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)	glycosphingolipid metabolic process	Biological process	-
KCNA6	3742	potassium channel, voltage gated shaker related subfamily A, member 6	potassium channel complex	Cellular component	-
TADA2A	6871	transcriptional adaptor 2A	DNA binding	Molecular function	-
BEX2	84707	brain expressed X-linked 2	cell cycle	Biological process	-
COL19A1	1310	collagen, type XIX, alpha 1	extracellular region	Cellular component	-
CENPN	55839	centromere protein N	mitotic nuclear division	Biological process	-
OCLN	100506658	occludin	cell-cell junction	Cellular component	19332538
ADSSL1	122622	adenylosuccinate synthase like 1	cytoplasm	Cellular component	15786719
H1FNT	341567	H1 histone family, member N, testis-specific	multicellular organismal development	Biological process	-
ANK2	287	ankyrin 2, neuronal	cytosol	Cellular component	-
ABCA5	23461	ATP-binding cassette, sub-family A (ABC1), member 5	metabolic process	Biological process	-
SHROOM3	57619	shroom family member 3	actin filament binding	Molecular function	-
KDR	3791	kinase insert domain receptor	transmembrane receptor protein tyrosine kinase signaling pathway	Biological process	1417831
GRIK2	2898	glutamate receptor, ionotropic, kainate 2	kainate selective glutamate receptor activity	Molecular function	15537878
CAPG	822	capping protein (actin filament), gelsolin-like	centriole	Cellular component	19166812
IFNA1	3439	interferon, alpha 1	positive regulation of peptidyl-serine phosphorylation of STAT protein	Biological process	-
ESAM	90952	endothelial cell adhesion molecule	single organismal cell-cell adhesion	Biological process	-
CCL5	6352	chemokine (C-C motif) ligand 5	positive regulation of T cell chemotaxis	Biological process	16778803
PPIG	9360	peptidylprolyl isomerase G (cyclophilin G)	cytoplasm	Cellular component	-
SNRPE	6635	small nuclear ribonucleoprotein polypeptide E	hair cycle	Biological process	23246290
HSP90B1	7184	heat shock protein 90kDa beta (Grp94), member 1	sequestering of calcium ion	Biological process	15192333
DAND5	199699	DAN domain family member 5, BMP antagonist	sequestering of nodal from receptor via nodal binding	Biological process	-
GRHL1	29841	grainyhead-like 1 (Drosophila)	cytoplasm	Cellular component	-
CAV3	859	caveolin 3	protein complex scaffold	Molecular function	-
NOX5	79400	NADPH oxidase, EF-hand calcium binding domain 5	oxidation-reduction process	Biological process	11483596
VAMP7	6845	vesicle-associated membrane protein 7	apical part of cell	Cellular component	-
MT1A	4489	metallothionein 1A	cytoplasm	Cellular component	-
IMP3	55272	IMP3, U3 small nucleolar ribonucleoprotein	rRNA processing	Biological process	-
CD38	952	CD38 molecule	positive regulation of cytosolic calcium ion concentration	Biological process	-
DNA2	1763	DNA replication helicase/nuclease 2	mitotic cell cycle	Biological process	-
TOR1AIP2	163590	torsin A interacting protein 2	protein localization to nuclear envelope	Biological process	19339278
WNT11	7481	wingless-type MMTV integration site family, member 11	protein kinase activator activity	Molecular function	20103596
VAT1	10493	vesicle amine transport 1	integral component of membrane	Cellular component	8938427
CLCNKA	1187	chloride channel, voltage-sensitive Ka	transmembrane transport	Biological process	-
HOPX	84525	HOP homeobox	regulation of protein binding	Biological process	-
KLK8	11202	kallikrein-related peptidase 8	response to wounding	Biological process	-
SLC35B4	84912	solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4	UDP-N-acetylglucosamine transport	Biological process	15911612
PAWR	5074	PRKC, apoptosis, WT1, regulator	actin filament bundle assembly	Biological process	-
LAMC3	10319	laminin, gamma 3	visual perception	Biological process	-
CSK	1445	c-src tyrosine kinase	peptidyl-tyrosine autophosphorylation	Biological process	-
RPS8	6202	ribosomal protein S8	cellular protein metabolic process	Biological process	-
NRM	11270	nurim (nuclear envelope membrane protein)	nucleus	Cellular component	-
XPO1	7514	exportin 1	Ran GTPase binding	Molecular function	-
MMAB	326625	methylmalonic aciduria (cobalamin deficiency) cblB type	mitochondrial matrix	Cellular component	-
GTF2H1	2965	general transcription factor IIH, polypeptide 1, 62kDa	positive regulation of viral transcription	Biological process	-
MTRR	4552	5-methyltetrahydrofolate-homocysteine methyltransferase reductase	NADP binding	Molecular function	9501215
CCDC78	124093	coiled-coil domain containing 78	perinuclear region of cytoplasm	Cellular component	22818856
H2AFY2	55506	H2A histone family, member Y2	Barr body	Cellular component	11331621
HRH4	59340	histamine receptor H4	plasma membrane	Cellular component	-
HYOU1	10525	hypoxia up-regulated 1	endocytic vesicle lumen	Cellular component	-
COL4A1	1282	collagen, type IV, alpha 1	extracellular matrix disassembly	Biological process	-
DAB2IP	153090	DAB2 interacting protein	innate immune response	Biological process	-
CDC26	246184	cell division cycle 26	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
HDHD3	81932	haloacid dehalogenase-like hydrolase domain containing 3	protein binding	Molecular function	16189514
SCARB1	949	scavenger receptor class B, member 1	vitamin transmembrane transport	Biological process	11208913
ITGB3	3690	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	axon guidance	Biological process	-
RHBDL3	162494	rhomboid, veinlet-like 3 (Drosophila)	serine-type endopeptidase activity	Molecular function	-
HOXC4	3221	homeobox C4	HMG box domain binding	Molecular function	-
SPTLC2	9517	serine palmitoyltransferase, long chain base subunit 2	serine C-palmitoyltransferase complex	Cellular component	19416851
DBF4B	80174	DBF4 zinc finger B	positive regulation of nuclear cell cycle DNA replication	Biological process	15668232
DDB2	1643	damage-specific DNA binding protein 2, 48kDa	protein binding	Molecular function	12732143
TIGD4	201798	tigger transposable element derived 4	nucleus	Cellular component	-
UHMK1	127933	U2AF homology motif (UHM) kinase 1	RNA binding	Molecular function	-
BMP2	650	bone morphogenetic protein 2	embryo development	Biological process	-
GDPGP1	390637	GDP-D-glucose phosphorylase 1	cytoplasm	Cellular component	-
CBR4	84869	carbonyl reductase 4	NADPH dehydrogenase (quinone) activity	Molecular function	-
STK17A	9263	serine/threonine kinase 17a	regulation of reactive oxygen species metabolic process	Biological process	21489989
FPR2	2358	formyl peptide receptor 2	chemotaxis	Biological process	-
ATP6V1H	51606	ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H	viral process	Biological process	-
TUBGCP6	85378	tubulin, gamma complex associated protein 6	extracellular exosome	Cellular component	23376485
NFATC3	4775	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	15173172
RPL38	6169	ribosomal protein L38	viral transcription	Biological process	-
STK11	6794	serine/threonine kinase 11	negative regulation of cell growth	Biological process	-
OR52R1	119695	olfactory receptor, family 52, subfamily R, member 1 (gene/pseudogene)	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
WASF3	10810	WAS protein family, member 3	actin filament polymerization	Biological process	10381382
ADIPOR1	51094	adiponectin receptor 1	protein heterodimerization activity	Molecular function	-
MED8	112950	mediator complex subunit 8	regulation of transcription from RNA polymerase II promoter	Biological process	-
NPR2	4882	natriuretic peptide receptor 2	regulation of blood pressure	Biological process	10082481
OR1E3	8389	olfactory receptor, family 1, subfamily E, member 3 (gene/pseudogene)	plasma membrane	Cellular component	-
DSP	1832	desmoplakin	protein localization to adherens junction	Biological process	16917092
KLK13	26085	kallikrein-related peptidase 13	protein binding	Molecular function	14687906
NBN	4683	nibrin	DNA repair	Biological process	-
CBX1	10951	chromobox homolog 1	enzyme binding	Molecular function	19486527
SFT2D2	375035	SFT2 domain containing 2	protein transport	Biological process	-
TTLL11	158135	tubulin tyrosine ligase-like family member 11	cilium	Cellular component	-
GABRA2	2555	gamma-aminobutyric acid (GABA) A receptor, alpha 2	cell junction	Cellular component	-
ZC3HAV1	56829	zinc finger CCCH-type, antiviral 1	positive regulation of mRNA catabolic process	Biological process	21876179
USP12	219333	ubiquitin specific peptidase 12	ubiquitin-specific protease activity	Molecular function	19075014
PIGS	94005	phosphatidylinositol glycan anchor biosynthesis, class S	membrane	Cellular component	19946888
NMU	10874	neuromedin U	positive regulation of smooth muscle contraction	Biological process	-
LYPD3	27076	LY6/PLAUR domain containing 3	anchored component of plasma membrane	Cellular component	15012588
GSN	2934	gelsolin	cellular component disassembly involved in execution phase of apoptosis	Biological process	-
LAMTOR5	10542	late endosomal/lysosomal adaptor, MAPK and MTOR activator 5	viral genome replication	Biological process	-
PELI1	57162	pellino E3 ubiquitin protein ligase 1	positive regulation of protein ubiquitination	Biological process	-
MYO3A	53904	myosin IIIA	visual perception	Biological process	-
AURKB	9212	aurora kinase B	protein autophosphorylation	Biological process	19774610
QSOX1	5768	quiescin Q6 sulfhydryl oxidase 1	oxidation-reduction process	Biological process	-
HNRNPA1	3178	heterogeneous nuclear ribonucleoprotein A1	single-stranded RNA binding	Molecular function	8521471
DPM3	54344	dolichyl-phosphate mannosyltransferase polypeptide 3	membrane	Cellular component	19946888
SAR1B	51128	secretion associated, Ras related GTPase 1B	metal ion binding	Molecular function	-
CENPP	401541	centromere protein P	CENP-A containing nucleosome assembly	Biological process	-
CHRM2	1129	cholinergic receptor, muscarinic 2	postsynaptic membrane	Cellular component	-
KCNG1	3755	potassium channel, voltage gated modifier subfamily G, member 1	synaptic transmission	Biological process	-
NEUROD2	4761	neuronal differentiation 2	cellular response to electrical stimulus	Biological process	-
CYBA	1535	cytochrome b-245, alpha polypeptide	small GTPase mediated signal transduction	Biological process	-
DNM2	1785	dynamin 2	postsynaptic density	Cellular component	-
ACAD9	28976	acyl-CoA dehydrogenase family, member 9	mitochondrion	Cellular component	-
NUP62	23636	nucleoporin 62kDa	regulation of glucose transport	Biological process	-
PPARD	5467	peroxisome proliferator-activated receptor delta	protein binding	Molecular function	23455924
ARSK	153642	arylsulfatase family, member K	sphingolipid metabolic process	Biological process	-
HIST1H4K	8362	histone cluster 1, H4k	nucleosome assembly	Biological process	-
ATP1B1	481	ATPase, Na+/K+ transporting, beta 1 polypeptide	regulation of cardiac muscle contraction by calcium ion signaling	Biological process	-
IL18	3606	interleukin 18	positive regulation of interferon-gamma production	Biological process	19088061
TSC2	7249	tuberous sclerosis 2	viral process	Biological process	-
PRLHR	2834	prolactin releasing hormone receptor	neuropeptide signaling pathway	Biological process	9607765
SMARCA5	8467	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	DNA-templated transcription, initiation	Biological process	9836642
PFDN1	5201	prefoldin subunit 1	cerebellum development	Biological process	-
ACSF2	80221	acyl-CoA synthetase family member 2	fatty acid metabolic process	Biological process	-
LRCOL1	100507055	leucine rich colipase-like 1	lipid catabolic process	Biological process	-
HPGD	3248	hydroxyprostaglandin dehydrogenase 15-(NAD)	15-hydroxyprostaglandin dehydrogenase (NAD+) activity	Molecular function	-
ZNF7	7553	zinc finger protein 7	metal ion binding	Molecular function	-
MAP2K2	5605	mitogen-activated protein kinase kinase 2	Ras protein signal transduction	Biological process	-
NDUFV2	4729	NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa	2 iron, 2 sulfur cluster binding	Molecular function	-
APP	351	amyloid beta (A4) precursor protein	regulation of epidermal growth factor-activated receptor activity	Biological process	-
SLC7A6	9057	solute carrier family 7 (amino acid transporter light chain, y+L system), member 6	plasma membrane	Cellular component	-
LHCGR	3973	luteinizing hormone/choriogonadotropin receptor	choriogonadotropin hormone receptor activity	Molecular function	-
C9	735	complement component 9	extracellular exosome	Cellular component	19056867
ZSCAN10	84891	zinc finger and SCAN domain containing 10	sequence-specific DNA binding transcription factor activity	Molecular function	-
ZBTB34	403341	zinc finger and BTB domain containing 34	metal ion binding	Molecular function	-
CCAR1	55749	cell division cycle and apoptosis regulator 1	apoptotic process	Biological process	-
HSD17B6	8630	hydroxysteroid (17-beta) dehydrogenase 6	retinol dehydrogenase activity	Molecular function	-
NUDT16	131870	nudix (nucleoside diphosphate linked moiety X)-type motif 16	magnesium ion binding	Molecular function	17567574
FABP1	2168	fatty acid binding protein 1, liver	apical cortex	Cellular component	-
CAPZA2	830	capping protein (actin filament) muscle Z-line, alpha 2	F-actin capping protein complex	Cellular component	-
TERF2IP	54386	telomeric repeat binding factor 2, interacting protein	nuclear chromosome	Cellular component	10850490
SMG7	9887	SMG7 nonsense mediated mRNA decay factor	regulation of dephosphorylation	Biological process	15721257
GXYLT1	283464	glucoside xylosyltransferase 1	carbohydrate metabolic process	Biological process	-
PIGT	51604	phosphatidylinositol glycan anchor biosynthesis, class T	cytoplasmic membrane-bounded vesicle	Cellular component	-
CFL2	1073	cofilin 2 (muscle)	actin cytoskeleton	Cellular component	-
PIK3CG	5294	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	T cell chemotaxis	Biological process	18278175
POMC	5443	proopiomelanocortin	extracellular space	Cellular component	9620771
RNPS1	10921	RNA binding protein S1, serine-rich domain	protein binding	Molecular function	11477570
YWHAG	7532	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma	protein kinase C inhibitor activity	Molecular function	10433554
PLK4	10733	polo-like kinase 4	identical protein binding	Molecular function	-
CXADR	1525	coxsackie virus and adenovirus receptor	homotypic cell-cell adhesion	Biological process	11734628
HIST1H4H	8365	histone cluster 1, H4h	membrane	Cellular component	19946888
METTL14	57721	methyltransferase like 14	mRNA methylation	Biological process	24316715
UNC13B	10497	unc-13 homolog B (C. elegans)	synaptic transmission	Biological process	-
CSF1R	1436	colony stimulating factor 1 receptor	peptidyl-tyrosine phosphorylation	Biological process	20504948
ISG20	3669	interferon stimulated exonuclease gene 20kDa	metal ion binding	Molecular function	-
KIF1A	547	kinesin family member 1A	metabolic process	Biological process	7539720
PROX1	5629	prospero homeobox 1	positive regulation of cell cycle checkpoint	Biological process	-
FOXI1	2299	forkhead box I1	positive regulation of transcription from RNA polymerase II promoter	Biological process	19214237
SLC22A17	51310	solute carrier family 22, member 17	integral component of plasma membrane	Cellular component	17253959
RAB14	51552	RAB14, member RAS oncogene family	phagolysosome assembly involved in apoptotic cell clearance	Biological process	-
FCGR1B	2210	Fc fragment of IgG, high affinity Ib, receptor (CD64)	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	Biological process	-
ELL	8178	elongation factor RNA polymerase II	transcription elongation from RNA polymerase II promoter	Biological process	-
ITGA2	3673	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	hepatocyte differentiation	Biological process	-
AVPR2	554	arginine vasopressin receptor 2	plasma membrane	Cellular component	-
MAP2K5	5607	mitogen-activated protein kinase kinase 5	cellular response to laminar fluid shear stress	Biological process	20551324
IL10	3586	interleukin 10	regulation of complement-dependent cytotoxicity	Biological process	16034134
LDHB	3945	lactate dehydrogenase B	identical protein binding	Molecular function	-
GPR160	26996	G protein-coupled receptor 160	plasma membrane	Cellular component	-
IKZF1	10320	IKAROS family zinc finger 1 (Ikaros)	erythrocyte differentiation	Biological process	17934067
TNFSF12	8742	tumor necrosis factor (ligand) superfamily, member 12	receptor binding	Molecular function	9560343
DLX3	1747	distal-less homeobox 3	chromatin binding	Molecular function	-
STEAP4	79689	STEAP family member 4	copper ion import	Biological process	-
DYRK1A	1859	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	negative regulation of DNA damage response, signal transduction by p53 class mediator	Biological process	20736167
VKORC1L1	154807	vitamin K epoxide reductase complex, subunit 1-like 1	cellular response to oxidative stress	Biological process	21367861
RPL7	6129	ribosomal protein L7	gene expression	Biological process	-
TH	7054	tyrosine hydroxylase	memory	Biological process	-
SOX3	6658	SRY (sex determining region Y)-box 3	organ morphogenesis	Biological process	-
CARD17	440068	caspase recruitment domain family, member 17	cysteine-type endopeptidase inhibitor activity	Molecular function	-
TBPL2	387332	TATA box binding protein like 2	multicellular organismal development	Biological process	-
IRAK2	3656	interleukin-1 receptor-associated kinase 2	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	Biological process	-
PRKCZ	5590	protein kinase C, zeta	protein heterooligomerization	Biological process	-
ABCE1	6059	ATP-binding cassette, sub-family E (OABP), member 1	ATPase activity	Molecular function	-
CNOT6	57472	CCR4-NOT transcription complex, subunit 6	regulation of transcription, DNA-templated	Biological process	-
CAPZB	832	capping protein (actin filament) muscle Z-line, beta	regulation of cell morphogenesis	Biological process	21834987
CALM1	801	calmodulin 1 (phosphorylase kinase, delta)	innate immune response	Biological process	-
HGS	9146	hepatocyte growth factor-regulated tyrosine kinase substrate	endosome to lysosome transport	Biological process	-
CADM3	57863	cell adhesion molecule 3	integral component of membrane	Cellular component	-
FBLN7	129804	fibulin 7	extracellular exosome	Cellular component	23376485
SNCA	6622	synuclein, alpha (non A4 component of amyloid precursor)	response to lipopolysaccharide	Biological process	12406186
KIF2C	11004	kinesin family member 2C	mitotic nuclear division	Biological process	9434124
MYC	4609	v-myc avian myelocytomatosis viral oncogene homolog	nucleus	Cellular component	11793365
AGBL1	123624	ATP/GTP binding protein-like 1	cytosol	Cellular component	-
NDST1	3340	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	carbohydrate metabolic process	Biological process	-
SNW1	22938	SNW domain containing 1	positive regulation of histone H3-K4 methylation	Biological process	19818711
JUP	3728	junction plakoglobin	cell junction assembly	Biological process	-
SLC24A4	123041	solute carrier family 24 (sodium/potassium/calcium exchanger), member 4	potassium ion transport	Biological process	-
JAK1	3716	Janus kinase 1	cytoskeleton	Cellular component	-
TAX1BP1	8887	Tax1 (human T-cell leukemia virus type I) binding protein 1	negative regulation of type I interferon production	Biological process	-
TSNAX	7257	translin-associated factor X	protein transporter activity	Molecular function	9013868
BRF1	2972	BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit	rRNA transcription	Biological process	7624363
NEK11	79858	NIMA-related kinase 11	intracellular signal transduction	Biological process	15161910
CD84	8832	CD84 molecule	leukocyte migration	Biological process	-
STXBP6	29091	syntaxin binding protein 6 (amisyn)	plasma membrane	Cellular component	-
HTR4	3360	5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled	endosome	Cellular component	-
CD300LG	146894	CD300 molecule-like family member g	extracellular exosome	Cellular component	23376485
HIST1H4E	8367	histone cluster 1, H4e	nucleoplasm	Cellular component	-
HBP1	26959	HMG-box transcription factor 1	RNA binding	Molecular function	-
LINC01558	26238	long intergenic non-protein coding RNA 1558	molecular_function	Molecular function	-
ETV1	2115	ets variant 1	peripheral nervous system neuron development	Biological process	20096094
MED11	400569	mediator complex subunit 11	protein binding	Molecular function	12584197
GPR87	53836	G protein-coupled receptor 87	integral component of plasma membrane	Cellular component	-
HAND2	9464	heart and neural crest derivatives expressed 2	transcription, DNA-templated	Biological process	-
PPARG	5468	peroxisome proliferator-activated receptor gamma	peroxisome proliferator activated receptor signaling pathway	Biological process	20622039
MYEF2	50804	myelin expression factor 2	nucleoplasm	Cellular component	-
KEL	3792	Kell blood group, metallo-endopeptidase	integral component of membrane	Cellular component	9647734
ELANE	1991	elastase, neutrophil expressed	negative regulation of transcription from RNA polymerase II promoter	Biological process	19506020
TCTA	6988	T-cell leukemia translocation altered	integral component of membrane	Cellular component	-
RPN2	6185	ribophorin II	integral component of membrane	Cellular component	-
TP53	7157	tumor protein p53	protease binding	Molecular function	11923872
HESX1	8820	HESX homeobox 1	sequence-specific DNA binding	Molecular function	-
RAG2	5897	recombination activating gene 2	T cell lineage commitment	Biological process	-
CLIP3	25999	CAP-GLY domain containing linker protein 3	fat cell differentiation	Biological process	-
GNAI2	2771	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	cell proliferation	Biological process	-
PRMT1	3276	protein arginine methyltransferase 1	cytoplasm	Cellular component	9029147
CD2	914	CD2 molecule	cell surface	Cellular component	15345303
LDHAL6B	92483	lactate dehydrogenase A-like 6B	carbohydrate metabolic process	Biological process	-
ALCAM	214	activated leukocyte cell adhesion molecule	neuronal cell body	Cellular component	-
TNFAIP3	7128	tumor necrosis factor, alpha-induced protein 3	cellular response to lipopolysaccharide	Biological process	19912257
CCL16	6360	chemokine (C-C motif) ligand 16	cell communication	Biological process	9642106
NRXN2	9379	neurexin 2	gephyrin clustering involved in postsynaptic density assembly	Biological process	-
NRCAM	4897	neuronal cell adhesion molecule	protein localization	Biological process	-
NDNL2	56160	necdin-like 2	chromosome, telomeric region	Cellular component	-
VAPB	9217	VAMP (vesicle-associated membrane protein)-associated protein B and C	integral component of membrane	Cellular component	-
OR1L6	392390	olfactory receptor, family 1, subfamily L, member 6	G-protein coupled receptor activity	Molecular function	-
OR2W1	26692	olfactory receptor, family 2, subfamily W, member 1	integral component of membrane	Cellular component	-
ERF	2077	Ets2 repressor factor	trophoblast giant cell differentiation	Biological process	-
ZBTB16	7704	zinc finger and BTB domain containing 16	nucleus	Cellular component	-
SOX7	83595	SRY (sex determining region Y)-box 7	negative regulation of transcription, DNA-templated	Biological process	19108950
KLF10	7071	Kruppel-like factor 10	protein binding	Molecular function	10976766
MRC1	4360	mannose receptor, C type 1	protein binding	Molecular function	11222859
ADAP2	55803	ArfGAP with dual PH domains 2	inositol 1,3,4,5 tetrakisphosphate binding	Molecular function	14690521
ASB17	127247	ankyrin repeat and SOCS box containing 17	protein ubiquitination	Biological process	-
RP2	6102	retinitis pigmentosa 2 (X-linked recessive)	nucleoside diphosphate kinase activity	Molecular function	-
POLR3A	11128	polymerase (RNA) III (DNA directed) polypeptide A, 155kDa	regulation of mitochondrion degradation	Biological process	24912190
TRIM36	55521	tripartite motif containing 36	extracellular exosome	Cellular component	23376485
AK9	221264	adenylate kinase 9	dCMP phosphorylation	Biological process	23416111
TIPARP	25976	TCDD-inducible poly(ADP-ribose) polymerase	estrogen metabolic process	Biological process	-
DNAJC8	22826	DnaJ (Hsp40) homolog, subfamily C, member 8	nucleoplasm	Cellular component	-
ARNTL	406	aryl hydrocarbon receptor nuclear translocator-like	regulation of transcription, DNA-templated	Biological process	-
CYP4B1	1580	cytochrome P450, family 4, subfamily B, polypeptide 1	fluorene metabolic process	Biological process	-
ABCG4	64137	ATP-binding cassette, sub-family G (WHITE), member 4	plasma membrane	Cellular component	-
ADRA2C	152	adrenoceptor alpha 2C	alpha2-adrenergic receptor activity	Molecular function	17215105
MSH6	2956	mutS homolog 6	plasma membrane	Cellular component	-
LSM2	57819	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)	protein kinase binding	Molecular function	-
FARP1	10160	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)	synapse	Cellular component	-
HR	55806	hair growth associated	nuclear body	Cellular component	-
EML4	27436	echinoderm microtubule associated protein like 4	microtubule-based process	Biological process	10995578
ZNF419	79744	zinc finger protein 419	transcription, DNA-templated	Biological process	-
NLGN3	54413	neuroligin 3	regulation of synaptic transmission	Biological process	-
AADAC	13	arylacetamide deacetylase	deacetylase activity	Molecular function	9665742
APOA1	335	apolipoprotein A-I	endothelial cell proliferation	Biological process	-
ECE1	1889	endothelin converting enzyme 1	endopeptidase activity	Molecular function	18039931
OR1L8	138881	olfactory receptor, family 1, subfamily L, member 8	G-protein coupled receptor activity	Molecular function	-
CD36	948	CD36 molecule (thrombospondin receptor)	response to stilbenoid	Biological process	-
SAR1B	51128	secretion associated, Ras related GTPase 1B	cellular protein metabolic process	Biological process	-
IFNA7	3444	interferon, alpha 7	natural killer cell activation involved in immune response	Biological process	-
CCND1	595	cyclin D1	bicellular tight junction	Cellular component	-
MCF2L2	23101	MCF.2 cell line derived transforming sequence-like 2	positive regulation of GTPase activity	Biological process	-
WNT16	51384	wingless-type MMTV integration site family, member 16	keratinocyte proliferation	Biological process	17200136
IGFBP6	3489	insulin-like growth factor binding protein 6	regulation of cell growth	Biological process	-
RIPK2	8767	receptor-interacting serine-threonine kinase 2	TRIF-dependent toll-like receptor signaling pathway	Biological process	-
F11R	50848	F11 receptor	bicellular tight junction assembly	Biological process	-
PLTP	5360	phospholipid transfer protein	vitamin E biosynthetic process	Biological process	-
ECM1	1893	extracellular matrix protein 1	regulation of type 2 immune response	Biological process	-
VAV2	7410	vav 2 guanine nucleotide exchange factor	positive regulation of phosphatidylinositol 3-kinase activity	Biological process	-
WNT9B	7484	wingless-type MMTV integration site family, member 9B	mesonephric duct formation	Biological process	-
NOX1	27035	NADPH oxidase 1	voltage-gated proton channel activity	Molecular function	10615049
PTPRT	11122	protein tyrosine phosphatase, receptor type, T	signal transduction	Biological process	16973135
FZD6	8323	frizzled class receptor 6	protein binding	Molecular function	10347172
MMRN1	22915	multimerin 1	extracellular region	Cellular component	-
PEAK1	79834	pseudopodium-enriched atypical kinase 1	plasma membrane	Cellular component	-
PTPRC	5788	protein tyrosine phosphatase, receptor type, C	protein kinase binding	Molecular function	14625311
SEC24D	9871	SEC24 family member D	perinuclear region of cytoplasm	Cellular component	-
DPAGT1	1798	dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)	integral component of membrane	Cellular component	-
CHMP4A	29082	charged multivesicular body protein 4A	cytoplasm	Cellular component	21975012
SIRT6	51548	sirtuin 6	protein binding	Molecular function	19135889
GALNT4	8693	polypeptide N-acetylgalactosaminyltransferase 4	extracellular exosome	Cellular component	19199708
WDR60	55112	WD repeat domain 60	extracellular space	Cellular component	22664934
SORBS3	10174	sorbin and SH3 domain containing 3	structural constituent of cytoskeleton	Molecular function	9885244
CPNE7	27132	copine VII	lipid metabolic process	Biological process	10534407
HEY1	23462	hes-related family bHLH transcription factor with YRPW motif 1	microsatellite binding	Molecular function	21290414
UBE2B	7320	ubiquitin-conjugating enzyme E2B	HULC complex	Cellular component	19410543
TSFM	10102	Ts translation elongation factor, mitochondrial	nucleoplasm	Cellular component	-
SOX15	6665	SRY (sex determining region Y)-box 15	cell differentiation	Biological process	16759287
RBFOX2	23543	RNA binding protein, fox-1 homolog (C. elegans) 2	nucleotide binding	Molecular function	-
RBP4	5950	retinol binding protein 4, plasma	response to insulin	Biological process	-
ZAP70	7535	zeta-chain (TCR) associated protein kinase 70kDa	adaptive immune response	Biological process	20135127
MAP1A	4130	microtubule-associated protein 1A	microtubule associated complex	Cellular component	8812494
ABCA6	23460	ATP-binding cassette, sub-family A (ABC1), member 6	metabolic process	Biological process	-
MYC	4609	v-myc avian myelocytomatosis viral oncogene homolog	negative regulation of apoptotic process	Biological process	-
MKL1	57591	megakaryoblastic leukemia (translocation) 1	sequence-specific DNA binding transcription factor activity	Molecular function	-
PTH	5741	parathyroid hormone	positive regulation of glucose import	Biological process	21076856
PAG1	55824	phosphoprotein membrane anchor with glycosphingolipid microdomains 1	epidermal growth factor receptor signaling pathway	Biological process	-
APOA2	336	apolipoprotein A-II	triglyceride-rich lipoprotein particle remodeling	Biological process	14967812
ESPL1	9700	extra spindle pole bodies homolog 1 (S. cerevisiae)	mitotic cell cycle	Biological process	-
USP43	124739	ubiquitin specific peptidase 43	nucleoplasm	Cellular component	-
CACNA1C	775	calcium channel, voltage-dependent, L type, alpha 1C subunit	regulation of insulin secretion	Biological process	-
BMP7	655	bone morphogenetic protein 7	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
STXBP5	134957	syntaxin binding protein 5 (tomosyn)	regulation of exocytosis	Biological process	15217342
PGAM4	441531	phosphoglycerate mutase family member 4	dephosphorylation	Biological process	-
PTPN2	5771	protein tyrosine phosphatase, non-receptor type 2	negative regulation of lipid storage	Biological process	-
WT1	7490	Wilms tumor 1	glomerular basement membrane development	Biological process	19205749
GEMIN6	79833	gem (nuclear organelle) associated protein 6	SMN-Sm protein complex	Cellular component	18984161
ARX	170302	aristaless related homeobox	embryonic olfactory bulb interneuron precursor migration	Biological process	-
SMAD1	4086	SMAD family member 1	positive regulation of gene expression	Biological process	19664780
C1orf123	54987	chromosome 1 open reading frame 123	extracellular exosome	Cellular component	23376485
AREG	374	amphiregulin	growth factor activity	Molecular function	-
HES6	55502	hes family bHLH transcription factor 6	cell differentiation	Biological process	-
PTH	5741	parathyroid hormone	peptide hormone receptor binding	Molecular function	19674967
PLA2G4A	5321	phospholipase A2, group IVA (cytosolic, calcium-dependent)	phosphatidylserine acyl-chain remodeling	Biological process	-
KCNRG	283518	potassium channel regulator	identical protein binding	Molecular function	16189514
TAS2R19	259294	taste receptor, type 2, member 19	detection of chemical stimulus involved in sensory perception of bitter taste	Biological process	20022913
GLI3	2737	GLI family zinc finger 3	cilium	Cellular component	16254602
EPC1	80314	enhancer of polycomb homolog 1 (Drosophila)	Piccolo NuA4 histone acetyltransferase complex	Cellular component	14966270
DCTN6	10671	dynactin 6	dynactin complex	Cellular component	-
APOL1	8542	apolipoprotein L, 1	high-density lipoprotein particle	Cellular component	9325276
HLA-B	3106	major histocompatibility complex, class I, B	ER to Golgi transport vesicle membrane	Cellular component	-
PIK3CG	5294	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	G-protein coupled receptor signaling pathway	Biological process	12507995
LASP1	3927	LIM and SH3 protein 1	actin filament binding	Molecular function	-
PTPRO	5800	protein tyrosine phosphatase, receptor type, O	regulation of glomerular filtration	Biological process	-
CD180	4064	CD180 molecule	inflammatory response	Biological process	-
AKAP13	11214	A kinase (PRKA) anchor protein 13	membrane	Cellular component	19946888
B4GALT4	8702	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4	Golgi cisterna membrane	Cellular component	-
SFTPD	6441	surfactant protein D	proteinaceous extracellular matrix	Cellular component	-
MAPK8	5599	mitogen-activated protein kinase 8	TRIF-dependent toll-like receptor signaling pathway	Biological process	-
HOXB2	3212	homeobox B2	rhombomere 3 development	Biological process	-
ACP6	51205	acid phosphatase 6, lysophosphatidic	phospholipid metabolic process	Biological process	10506173
FAM132A	388581	family with sequence similarity 132, member A	hormone activity	Molecular function	-
PCM1	5108	pericentriolar material 1	interkinetic nuclear migration	Biological process	-
SYNE3	161176	spectrin repeat containing, nuclear envelope family member 3	integral component of membrane	Cellular component	-
CD24	100133941	CD24 molecule	glomerular parietal epithelial cell differentiation	Biological process	19092120
KPTN	11133	kaptin (actin binding protein)	nucleus	Cellular component	1372044
CTBP2	1488	C-terminal binding protein 2	positive regulation of transcription from RNA polymerase II promoter	Biological process	23775127
MTOR	2475	mechanistic target of rapamycin (serine/threonine kinase)	cellular response to heat	Biological process	-
CEP192	55125	centrosomal protein 192kDa	organelle organization	Biological process	-
DAP3	7818	death associated protein 3	mitochondrial inner membrane	Cellular component	-
NOD2	64127	nucleotide-binding oligomerization domain containing 2	negative regulation of interleukin-2 production	Biological process	-
HUS1	3364	HUS1 checkpoint homolog (S. pombe)	negative regulation of DNA replication	Biological process	-
PMS2	5395	PMS2 postmeiotic segregation increased 2 (S. cerevisiae)	ATP binding	Molecular function	-
PROM1	8842	prominin 1	brush border	Cellular component	-
LCOR	84458	ligand dependent nuclear receptor corepressor	sequence-specific DNA binding transcription factor activity	Molecular function	-
CATSPERB	79820	catsper channel auxiliary subunit beta	multicellular organism reproduction	Biological process	-
RAC1	5879	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	enzyme binding	Molecular function	16636067
MAP3K2	10746	mitogen-activated protein kinase kinase kinase 2	cellular response to mechanical stimulus	Biological process	19593445
SP100	6672	SP100 nuclear antigen	regulation of angiogenesis	Biological process	15592518
Sep-07	989	septin 7	cleavage furrow	Cellular component	-
CLCA1	1179	chloride channel accessory 1	integral component of plasma membrane	Cellular component	9828122
FZD5	7855	frizzled class receptor 5	chorionic trophoblast cell differentiation	Biological process	-
NCOR1	9611	nuclear receptor corepressor 1	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
TOB1	10140	transducer of ERBB2, 1	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	Biological process	21336257
RARA	5914	retinoic acid receptor, alpha	embryonic camera-type eye development	Biological process	-
LMCD1	29995	LIM and cysteine-rich domains 1	cytoplasm	Cellular component	-
NLGN4Y	22829	neuroligin 4, Y-linked	neuron cell-cell adhesion	Biological process	18923512
NPR1	4881	natriuretic peptide receptor 1	receptor guanylyl cyclase signaling pathway	Biological process	1672777
UGGT2	55757	UDP-glucose glycoprotein glucosyltransferase 2	endoplasmic reticulum lumen	Cellular component	-
DDIT3	1649	DNA-damage-inducible transcript 3	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	Biological process	14685163
POLE3	54107	polymerase (DNA directed), epsilon 3, accessory subunit	DNA biosynthetic process	Biological process	10801849
BAK1	578	BCL2-antagonist/killer 1	response to fungus	Biological process	-
AGTRAP	57085	angiotensin II receptor-associated protein	Golgi membrane	Cellular component	-
HSFY1	86614	heat shock transcription factor, Y-linked 1	nucleus	Cellular component	-
SEC22B	9554	SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)	Golgi membrane	Cellular component	-
GALNT14	79623	polypeptide N-acetylgalactosaminyltransferase 14	protein O-linked glycosylation	Biological process	-
AMY2A	279	amylase, alpha 2A (pancreatic)	calcium ion binding	Molecular function	10769135
HOXC11	3227	homeobox C11	cytoplasm	Cellular component	-
MGMT	4255	O-6-methylguanine-DNA methyltransferase	methylated-DNA-[protein]-cysteine S-methyltransferase activity	Molecular function	-
PRCP	5547	prolylcarboxypeptidase (angiotensinase C)	protein binding	Molecular function	20517885
DUSP16	80824	dual specificity phosphatase 16	cytosol	Cellular component	-
ATP5O	539	ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit	proton-transporting ATP synthase activity, rotational mechanism	Molecular function	-
GTF2F1	2962	general transcription factor IIF, polypeptide 1, 74kDa	RNA splicing	Biological process	-
TSC22D1	8848	TSC22 domain family, member 1	regulation of transcription, DNA-templated	Biological process	-
APOA4	337	apolipoprotein A-IV	positive regulation of fatty acid biosynthetic process	Biological process	2307668
PDGFB	5155	platelet-derived growth factor beta polypeptide	platelet activation	Biological process	-
PDGFA	5154	platelet-derived growth factor alpha polypeptide	fibroblast growth factor receptor signaling pathway	Biological process	-
PICK1	9463	protein interacting with PRKCA 1	metal ion binding	Molecular function	-
HDAC7	51564	histone deacetylase 7	cellular protein metabolic process	Biological process	-
AP2M1	1173	adaptor-related protein complex 2, mu 1 subunit	AP-2 adaptor complex	Cellular component	12121421
ABL1	25	ABL proto-oncogene 1, non-receptor tyrosine kinase	actin filament branching	Biological process	-
RARA	5914	retinoic acid receptor, alpha	positive regulation of neuron differentiation	Biological process	-
GRIN1	2902	glutamate receptor, ionotropic, N-methyl D-aspartate 1	calcium ion binding	Molecular function	-
CNKSR1	10256	connector enhancer of kinase suppressor of Ras 1	cell-cell junction	Cellular component	9814705
ROBO2	6092	roundabout, axon guidance receptor, homolog 2 (Drosophila)	olfactory bulb interneuron development	Biological process	-
ITCH	83737	itchy E3 ubiquitin protein ligase	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	-
PICK1	9463	protein interacting with PRKCA 1	neuronal postsynaptic density	Cellular component	-
NEK1	4750	NIMA-related kinase 1	protein binding	Molecular function	14690447
WNT11	7481	wingless-type MMTV integration site family, member 11	negative regulation of fibroblast growth factor production	Biological process	-
CNKSR3	154043	CNKSR family member 3	negative regulation of ERK1 and ERK2 cascade	Biological process	-
PPP1CC	5501	protein phosphatase 1, catalytic subunit, gamma isozyme	cytoplasm	Cellular component	11739654
ANGPT1	284	angiopoietin 1	positive regulation of receptor internalization	Biological process	19424712
RAF1	5894	Raf-1 proto-oncogene, serine/threonine kinase	cytoplasm	Cellular component	-
ZFP28	140612	ZFP28 zinc finger protein	regulation of transcription, DNA-templated	Biological process	-
CHD7	55636	chromodomain helicase DNA binding protein 7	chromatin modification	Biological process	-
NEDD4	4734	neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase	beta-2 adrenergic receptor binding	Molecular function	18544533
LGALS3BP	3959	lectin, galactoside-binding, soluble, 3 binding protein	extracellular space	Cellular component	16502470
NOS1	4842	nitric oxide synthase 1 (neuronal)	negative regulation of serotonin uptake	Biological process	-
CAPNS2	84290	calpain, small subunit 2	proteolysis	Biological process	-
EMP2	2013	epithelial membrane protein 2	blood vessel endothelial cell migration	Biological process	23439602
GIPR	2696	gastric inhibitory polypeptide receptor	positive regulation of cytosolic calcium ion concentration	Biological process	-
HEYL	26508	hes-related family bHLH transcription factor with YRPW motif-like	cytoplasm	Cellular component	-
ARSJ	79642	arylsulfatase family, member J	endoplasmic reticulum lumen	Cellular component	-
CDH3	1001	cadherin 3, type 1, P-cadherin (placental)	visual perception	Biological process	-
PIGS	94005	phosphatidylinositol glycan anchor biosynthesis, class S	attachment of GPI anchor to protein	Biological process	11483512
APTX	54840	aprataxin	polynucleotide 3' dephosphorylation	Biological process	17519253
BLOC1S6	26258	biogenesis of lysosomal organelles complex-1, subunit 6, pallidin	cytoplasm	Cellular component	-
NNAT	4826	neuronatin	neuron differentiation	Biological process	-
SMG6	23293	SMG6 nonsense mediated mRNA decay factor	exon-exon junction complex	Cellular component	20930030
SCARA5	286133	scavenger receptor class A, member 5	endocytosis	Biological process	-
SLC4A10	57282	solute carrier family 4, sodium bicarbonate transporter, member 10	anion transmembrane transport	Biological process	-
TESC	54997	tescalcin	male gonad development	Biological process	-
MESP1	55897	mesoderm posterior basic helix-loop-helix transcription factor 1	enhancer binding	Molecular function	-
TFDP1	7027	transcription factor Dp-1	transcription factor complex	Cellular component	-
HS3ST2	9956	heparan sulfate (glucosamine) 3-O-sulfotransferase 2	circadian rhythm	Biological process	-
TRIB3	57761	tribbles pseudokinase 3	cellular response to insulin stimulus	Biological process	12791994
ATP8B1	5205	ATPase, aminophospholipid transporter, class I, type 8B, member 1	negative regulation of transcription, DNA-templated	Biological process	16628629
MBOAT7	79143	membrane bound O-acyltransferase domain containing 7	integral component of membrane	Cellular component	-
HNRNPAB	3182	heterogeneous nuclear ribonucleoprotein A/B	cytoplasm	Cellular component	-
TPPP	11076	tubulin polymerization promoting protein	positive regulation of protein polymerization	Biological process	15590652
FGR	2268	FGR proto-oncogene, Src family tyrosine kinase	plasma membrane	Cellular component	-
SPAG9	9043	sperm associated antigen 9	mitogen-activated protein kinase p38 binding	Molecular function	-
ZNF57	126295	zinc finger protein 57	transcription, DNA-templated	Biological process	-
CORO1A	11151	coronin, actin binding protein, 1A	cell-substrate adhesion	Biological process	17442961
NR6A1	2649	nuclear receptor subfamily 6, group A, member 1	gene expression	Biological process	-
SACS	26278	sacsin molecular chaperone	mitochondrion	Cellular component	19208651
SYT4	6860	synaptotagmin IV	negative regulation of calcium ion-dependent exocytosis	Biological process	-
TREM1	54210	triggering receptor expressed on myeloid cells 1	integral component of membrane	Cellular component	-
ADARB2	105	adenosine deaminase, RNA-specific, B2 (non-functional)	poly(A) RNA binding	Molecular function	22658674
PSEN1	5663	presenilin 1	Golgi membrane	Cellular component	-
LPIN1	23175	lipin 1	actin cytoskeleton reorganization	Biological process	-
FRMD6	122786	FERM domain containing 6	apical constriction	Biological process	-
CMPK1	51727	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic	nucleoside diphosphate kinase activity	Molecular function	23416111
EPHA4	2043	EPH receptor A4	cell junction	Cellular component	-
NFE2L2	4780	nuclear factor, erythroid 2-like 2	cellular response to tumor necrosis factor	Biological process	18202225
FOXA2	3170	forkhead box A2	neuron fate specification	Biological process	-
UQCRH	7388	ubiquinol-cytochrome c reductase hinge protein	ubiquinol-cytochrome-c reductase activity	Molecular function	-
UBXN1	51035	UBX domain protein 1	proteasome complex	Cellular component	15362974
TAB3	257397	TGF-beta activated kinase 1/MAP3K7 binding protein 3	toll-like receptor 10 signaling pathway	Biological process	-
PASK	23178	PAS domain containing serine/threonine kinase	protein phosphorylation	Biological process	16275910
SOD2	6648	superoxide dismutase 2, mitochondrial	regulation of mitochondrial membrane potential	Biological process	-
MAP2K2	5605	mitogen-activated protein kinase kinase 2	innate immune response	Biological process	-
MYOG	4656	myogenin (myogenic factor 4)	sequence-specific DNA binding	Molecular function	11076940
ACOX3	8310	acyl-CoA oxidase 3, pristanoyl	cellular lipid metabolic process	Biological process	-
DYRK2	8445	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2	protein serine/threonine/tyrosine kinase activity	Molecular function	-
NEXN	91624	nexilin (F actin binding protein)	regulation of apoptotic process	Biological process	-
NRG1	3084	neuregulin 1	glial cell fate commitment	Biological process	-
RYR1	6261	ryanodine receptor 1 (skeletal)	smooth endoplasmic reticulum	Cellular component	-
C2CD4A	145741	C2 calcium-dependent domain containing 4A	plasma membrane	Cellular component	-
HNF1A	6927	HNF1 homeobox A	nucleoplasm	Cellular component	-
APOC2	344	apolipoprotein C-II	negative regulation of very-low-density lipoprotein particle clearance	Biological process	1917954
CD24	100133941	CD24 molecule	T cell costimulation	Biological process	11272271
CCNB1	891	cyclin B1	response to drug	Biological process	-
TEP1	7011	telomerase-associated protein 1	nuclear matrix	Cellular component	7876352
ETV4	2118	ets variant 4	branching involved in mammary gland duct morphogenesis	Biological process	-
GPD1L	23171	glycerol-3-phosphate dehydrogenase 1-like	regulation of heart rate	Biological process	17967977
POLR1B	84172	polymerase (RNA) I polypeptide B, 128kDa	DNA-directed RNA polymerase I complex	Cellular component	-
CNTFR	1271	ciliary neurotrophic factor receptor	nervous system development	Biological process	7585948
FBXL5	26234	F-box and leucine-rich repeat protein 5	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological process	17532294
CYGB	114757	cytoglobin	oxygen transport	Biological process	11919282
S1PR3	1903	sphingosine-1-phosphate receptor 3	lipid binding	Molecular function	9409733
TOP1	7150	topoisomerase (DNA) I	response to drug	Biological process	16127745
MRPS2	51116	mitochondrial ribosomal protein S2	translation	Biological process	-
DACH1	1602	dachshund family transcription factor 1	negative regulation of fibroblast proliferation	Biological process	-
PPT1	5538	palmitoyl-protein thioesterase 1	synaptic vesicle	Cellular component	12483688
CD36	948	CD36 molecule (thrombospondin receptor)	cGMP-mediated signaling	Biological process	17416590
TP53TG5	27296	TP53 target 5	negative regulation of cell growth	Biological process	10719363
BLOC1S5	63915	biogenesis of lysosomal organelles complex-1, subunit 5, muted	melanosome transport	Biological process	17182842
FLOT2	2319	flotillin 2	uropod	Cellular component	21696602
PRKCSH	5589	protein kinase C substrate 80K-H	cellular protein metabolic process	Biological process	-
IFNAR1	3454	interferon (alpha, beta and omega) receptor 1	regulation of type I interferon-mediated signaling pathway	Biological process	-
PPP2CA	5515	protein phosphatase 2, catalytic subunit, alpha isozyme	mitotic nuclear envelope reassembly	Biological process	-
C1S	716	complement component 1, s subcomponent	protein binding	Molecular function	12788922
IRAK3	11213	interleukin-1 receptor-associated kinase 3	protein homodimerization activity	Molecular function	10383454
POU2F1	5451	POU class 2 homeobox 1	intracellular membrane-bounded organelle	Cellular component	-
SLC35B3	51000	solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3	activation of mitophagy in response to mitochondrial depolarization	Biological process	22020285
RAB12	201475	RAB12, member RAS oncogene family	lysosome	Cellular component	-
LACTB	114294	lactamase, beta	metabolic process	Biological process	-
PIK3R2	5296	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	phosphatidylinositol 3-kinase signaling	Biological process	23604317
PRDM11	56981	PR domain containing 11	methyltransferase activity	Molecular function	-
ENPP2	5168	ectonucleotide pyrophosphatase/phosphodiesterase 2	movement of cell or subcellular component	Biological process	1733949
VPS35	55737	vacuolar protein sorting 35 homolog (S. cerevisiae)	transcytosis	Biological process	15247922
CAPZA1	829	capping protein (actin filament) muscle Z-line, alpha 1	cytoskeleton	Cellular component	16130169
ZSWIM2	151112	zinc finger, SWIM-type containing 2	apoptotic process	Biological process	-
POU5F1	5460	POU class 5 homeobox 1	regulation of heart induction by regulation of canonical Wnt signaling pathway	Biological process	19736317
CHD9	80205	chromodomain helicase DNA binding protein 9	nucleus	Cellular component	-
ZNF16	7564	zinc finger protein 16	positive regulation of erythrocyte differentiation	Biological process	16628192
SLC39A12	221074	solute carrier family 39 (zinc transporter), member 12	extracellular vesicle	Cellular component	24769233
NOD2	64127	nucleotide-binding oligomerization domain containing 2	negative regulation of interleukin-12 production	Biological process	-
SLCO1A2	6579	solute carrier organic anion transporter family, member 1A2	bile acid and bile salt transport	Biological process	-
SNAP25	6616	synaptosomal-associated protein, 25kDa	small molecule metabolic process	Biological process	-
OR10R2	343406	olfactory receptor, family 10, subfamily R, member 2	integral component of membrane	Cellular component	-
CD209	30835	CD209 molecule	endocytosis	Biological process	-
NCKAP1	10787	NCK-associated protein 1	paraxial mesoderm morphogenesis	Biological process	-
PEX19	5824	peroxisomal biogenesis factor 19	peroxisomal membrane	Cellular component	15713480
ASPN	54829	asporin	negative regulation of transforming growth factor beta receptor signaling pathway	Biological process	17827158
RNF31	55072	ring finger protein 31	LUBAC complex	Cellular component	17006537
DRD2	1813	dopamine receptor D2	negative regulation of circadian sleep/wake cycle, sleep	Biological process	-
KIF5A	3798	kinesin family member 5A	microtubule-based movement	Biological process	-
TRPM8	79054	transient receptor potential cation channel, subfamily M, member 8	calcium channel activity	Molecular function	-
FGF2	2247	fibroblast growth factor 2 (basic)	insulin receptor signaling pathway	Biological process	-
SOX4	6659	SRY (sex determining region Y)-box 4	positive regulation of canonical Wnt signaling pathway	Biological process	-
TUBA1A	7846	tubulin, alpha 1a	structural molecule activity	Molecular function	12090300
BLVRB	645	biliverdin reductase B	riboflavin reductase (NADPH) activity	Molecular function	11224564
ARFGEF2	10564	ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)	cytoplasmic membrane-bounded vesicle	Cellular component	-
PIN1	5300	peptidylprolyl cis/trans isomerase, NIMA-interacting 1	nuclear speck	Cellular component	-
ITGB1	3688	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	basement membrane	Cellular component	-
PTPN11	5781	protein tyrosine phosphatase, non-receptor type 11	inner ear development	Biological process	12058348
IMPDH2	3615	IMP (inosine 5'-monophosphate) dehydrogenase 2	metal ion binding	Molecular function	-
PCSK9	255738	proprotein convertase subtilisin/kexin type 9	serine-type endopeptidase activity	Molecular function	12552133
NDST1	3340	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	glycosaminoglycan metabolic process	Biological process	-
EPHB4	2050	EPH receptor B4	transmembrane receptor protein tyrosine kinase activity	Molecular function	8188704
PPP3CB	5532	protein phosphatase 3, catalytic subunit, beta isozyme	calmodulin-dependent protein phosphatase activity	Molecular function	2556704
FBXO17	115290	F-box protein 17	SCF ubiquitin ligase complex	Cellular component	18203720
NMB	4828	neuromedin B	cell-cell signaling	Biological process	2458345
SNX5	27131	sorting nexin 5	pinocytosis	Biological process	18854019
EDN3	1908	endothelin 3	hormone activity	Molecular function	10770212
CDT1	81620	chromatin licensing and DNA replication factor 1	mitotic cell cycle	Biological process	-
APP	351	amyloid beta (A4) precursor protein	axon cargo transport	Biological process	-
PPP2CB	5516	protein phosphatase 2, catalytic subunit, beta isozyme	nucleus	Cellular component	-
FSCN1	6624	fascin actin-bundling protein 1	actin filament binding	Molecular function	17671164
SERPINB9	5272	serpin peptidase inhibitor, clade B (ovalbumin), member 9	apoptotic process	Biological process	17479112
ZNF865	100507290	zinc finger protein 865	nucleus	Cellular component	-
EGF	1950	epidermal growth factor	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	-
EEF1G	1937	eukaryotic translation elongation factor 1 gamma	translation	Biological process	-
ARG2	384	arginase 2	mitochondrion	Cellular component	8898077
OR8G1	26494	olfactory receptor, family 8, subfamily G, member 1 (gene/pseudogene)	olfactory receptor activity	Molecular function	9119360
SEC24B	10427	SEC24 family member B	cellular protein metabolic process	Biological process	-
CREBBP	1387	CREB binding protein	zinc ion binding	Molecular function	-
FADS1	3992	fatty acid desaturase 1	alpha-linolenic acid metabolic process	Biological process	-
CIZ1	25792	CDKN1A interacting zinc finger protein 1	protein binding	Molecular function	18654987
PNISR	25957	PNN-interacting serine/arginine-rich protein	nucleus	Cellular component	-
EYA3	2140	EYA transcriptional coactivator and phosphatase 3	protein tyrosine phosphatase activity	Molecular function	19234442
LCP2	3937	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	cytosol	Cellular component	-
PDE2A	5138	phosphodiesterase 2A, cGMP-stimulated	protein homodimerization activity	Molecular function	19828435
IL10	3586	interleukin 10	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
NCR1	9437	natural cytotoxicity triggering receptor 1	integral component of plasma membrane	Cellular component	9730896
SPA17	53340	sperm autoantigenic protein 17	calmodulin binding	Molecular function	-
EPS15	2060	epidermal growth factor receptor pathway substrate 15	aggresome	Cellular component	16159959
STAT5A	6776	signal transducer and activator of transcription 5A	JAK-STAT cascade involved in growth hormone signaling pathway	Biological process	-
SLURP1	57152	secreted LY6/PLAUR domain containing 1	cell activation	Biological process	11285253
BECN1	8678	beclin 1, autophagy related	mitochondrial membrane	Cellular component	-
SPHK1	8877	sphingosine kinase 1	positive regulation of NF-kappaB transcription factor activity	Biological process	20577214
NSRP1	84081	nuclear speckle splicing regulatory protein 1	developmental process	Biological process	21296756
SLC8B1	80024	solute carrier family 8 (sodium/lithium/calcium exchanger), member B1	cytosol	Cellular component	20018762
PVRL1	5818	poliovirus receptor-related 1 (herpesvirus entry mediator C)	single organismal cell-cell adhesion	Biological process	12885915
KAZN	23254	kazrin, periplakin interacting protein	cytoplasm	Cellular component	-
KDM3B	51780	lysine (K)-specific demethylase 3B	transcription, DNA-templated	Biological process	-
ATP5G2	517	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)	mitochondrial outer membrane	Cellular component	-
PARVB	29780	parvin, beta	cell adhesion	Biological process	-
ZBED2	79413	zinc finger, BED-type containing 2	metal ion binding	Molecular function	-
TOX3	27324	TOX high mobility group box family member 3	positive regulation of transcription, DNA-templated	Biological process	21172805
RAC1	5879	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	dendrite morphogenesis	Biological process	-
PDCD6IP	10015	programmed cell death 6 interacting protein	protein homodimerization activity	Molecular function	14505570
HSPG2	3339	heparan sulfate proteoglycan 2	cardiac muscle tissue development	Biological process	-
ARSH	347527	arylsulfatase family, member H	integral component of membrane	Cellular component	-
MYO7A	4647	myosin VIIA	actin filament binding	Molecular function	21687988
SLC12A1	6557	solute carrier family 12 (sodium/potassium/chloride transporter), member 1	transmembrane transport	Biological process	-
HYDIN	54768	HYDIN, axonemal central pair apparatus protein	cilium	Cellular component	-
COMMD1	150684	copper metabolism (Murr1) domain containing 1	negative regulation of sodium ion transmembrane transport	Biological process	20237237
ZFYVE9	9372	zinc finger, FYVE domain containing 9	transforming growth factor beta receptor signaling pathway	Biological process	-
MNAT1	4331	MNAT CDK-activating kinase assembly factor 1	transcription elongation from RNA polymerase I promoter	Biological process	-
ATL1	51062	atlastin GTPase 1	Golgi membrane	Cellular component	-
FOXM1	2305	forkhead box M1	regulation of cell cycle	Biological process	-
ABCA5	23461	ATP-binding cassette, sub-family A (ABC1), member 5	negative regulation of macrophage derived foam cell differentiation	Biological process	20382126
RILP	83547	Rab interacting lysosomal protein	late endosome membrane	Cellular component	-
PHACTR1	221692	phosphatase and actin regulator 1	protein phosphatase inhibitor activity	Molecular function	-
LRRC3B	116135	leucine rich repeat containing 3B	integral component of membrane	Cellular component	-
FYN	2534	FYN proto-oncogene, Src family tyrosine kinase	protein binding	Molecular function	10209036
ITGB1	3688	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	response to drug	Biological process	-
TMEM175	84286	transmembrane protein 175	lysosomal membrane	Cellular component	17897319
SLC12A6	9990	solute carrier family 12 (potassium/chloride transporter), member 6	plasma membrane	Cellular component	-
OR6T1	219874	olfactory receptor, family 6, subfamily T, member 1	G-protein coupled receptor activity	Molecular function	-
ELF5	2001	E74-like factor 5 (ets domain transcription factor)	nucleus	Cellular component	-
CLK3	1198	CDC-like kinase 3	peptidyl-tyrosine phosphorylation	Biological process	-
GSK3A	2931	glycogen synthase kinase 3 alpha	protein phosphorylation	Biological process	11035810
ITGA2B	3674	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	cell surface	Cellular component	23382103
CREB3L3	84699	cAMP responsive element binding protein 3-like 3	endoplasmic reticulum	Cellular component	16236796
GNG10	2790	guanine nucleotide binding protein (G protein), gamma 10	small molecule metabolic process	Biological process	-
CTAG2	30848	cancer/testis antigen 2	protein binding	Molecular function	25416956
CADM2	253559	cell adhesion molecule 2	brain development	Biological process	-
NEURL2	140825	neuralized E3 ubiquitin protein ligase 2	sarcomere organization	Biological process	-
BPY2C	442868	basic charge, Y-linked, 2C	spermatogenesis	Biological process	12724276
PANX2	56666	pannexin 2	integral component of membrane	Cellular component	-
OR5R1	219479	olfactory receptor, family 5, subfamily R, member 1 (gene/pseudogene)	sensory perception of smell	Biological process	-
MTAP	4507	methylthioadenosine phosphorylase	L-methionine biosynthetic process from methylthioadenosine	Biological process	-
KRTAP4-5	85289	keratin associated protein 4-5	aging	Biological process	21916889
GLI2	2736	GLI family zinc finger 2	mammary gland development	Biological process	-
FCER2	2208	Fc fragment of IgE, low affinity II, receptor for (CD23)	positive regulation of nitric-oxide synthase biosynthetic process	Biological process	7544003
MIF	4282	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	extracellular space	Cellular component	-
OR5T3	390154	olfactory receptor, family 5, subfamily T, member 3	plasma membrane	Cellular component	-
RPL11	6135	ribosomal protein L11	membrane	Cellular component	19946888
NGF	4803	nerve growth factor (beta polypeptide)	positive regulation of axon extension	Biological process	-
ACTN4	81	actinin, alpha 4	calcium ion binding	Molecular function	-
SUSD3	203328	sushi domain containing 3	integral component of membrane	Cellular component	-
PRKAA2	5563	protein kinase, AMP-activated, alpha 2 catalytic subunit	protein serine/threonine/tyrosine kinase activity	Molecular function	22797923
WNT2	7472	wingless-type MMTV integration site family member 2	extracellular space	Cellular component	-
TRPC1	7220	transient receptor potential cation channel, subfamily C, member 1	cytosol	Cellular component	19052258
ETS1	2113	v-ets avian erythroblastosis virus E26 oncogene homolog 1	transcription factor binding	Molecular function	10698492
SLC32A1	140679	solute carrier family 32 (GABA vesicular transporter), member 1	transmembrane transport	Biological process	-
NTRK1	4914	neurotrophic tyrosine kinase, receptor, type 1	mechanoreceptor differentiation	Biological process	-
CHD7	55636	chromodomain helicase DNA binding protein 7	adult heart development	Biological process	-
RIMBP3	85376	RIMS binding protein 3	protein binding	Molecular function	25416956
HNRNPA0	10949	heterogeneous nuclear ribonucleoprotein A0	ribonucleoprotein complex	Cellular component	-
PHC2	1912	polyhomeotic homolog 2 (Drosophila)	protein binding	Molecular function	10976766
PRSS53	339105	protease, serine, 53	serine-type endopeptidase activity	Molecular function	-
HMOX1	3162	heme oxygenase 1	intrinsic apoptotic signaling pathway in response to DNA damage	Biological process	-
CDK12	51755	cyclin-dependent kinase 12	phosphorylation of RNA polymerase II C-terminal domain	Biological process	20952539
SULF1	23213	sulfatase 1	plasma membrane	Cellular component	-
SKI	6497	SKI proto-oncogene	anterior/posterior axis specification	Biological process	-
SLC25A18	83733	solute carrier family 25 (glutamate carrier), member 18	protein binding	Molecular function	25416956
ADRA2A	150	adrenoceptor alpha 2A	negative regulation of adenylate cyclase activity	Biological process	1354394
AOC1	26	amine oxidase, copper containing 1	cellular response to azide	Biological process	16846222
LIG1	3978	ligase I, DNA, ATP-dependent	DNA ligase activity	Molecular function	15871698
ERCC2	2068	excision repair cross-complementation group 2	nucleotide-excision repair	Biological process	-
B4GALT1	2683	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	protein homodimerization activity	Molecular function	7744867
PI4KB	5298	phosphatidylinositol 4-kinase, catalytic, beta	perinuclear region of cytoplasm	Cellular component	-
PIGH	5283	phosphatidylinositol glycan anchor biosynthesis, class H	phosphatidylinositol N-acetylglucosaminyltransferase activity	Molecular function	-
CXCL9	4283	chemokine (C-X-C motif) ligand 9	positive regulation of myoblast fusion	Biological process	-
OR9Q1	219956	olfactory receptor, family 9, subfamily Q, member 1	odorant binding	Molecular function	-
PLCG1	5335	phospholipase C, gamma 1	Fc-gamma receptor signaling pathway involved in phagocytosis	Biological process	-
RPS4Y1	6192	ribosomal protein S4, Y-linked 1	translational initiation	Biological process	-
FAP	2191	fibroblast activation protein, alpha	negative regulation of cell proliferation involved in contact inhibition	Biological process	-
TADA2A	6871	transcriptional adaptor 2A	sequence-specific DNA binding transcription factor activity	Molecular function	8552087
NUDT1	4521	nudix (nucleoside diphosphate linked moiety X)-type motif 1	dATP catabolic process	Biological process	10373420
GJA1	2697	gap junction protein, alpha 1, 43kDa	milk ejection	Biological process	-
NME2	4831	NME/NM23 nucleoside diphosphate kinase 2	UTP biosynthetic process	Biological process	-
ZNF232	7775	zinc finger protein 232	metal ion binding	Molecular function	-
FAM26F	441168	family with sequence similarity 26, member F	cation transmembrane transport	Biological process	-
NUP155	9631	nucleoporin 155kDa	cellular response to heat	Biological process	-
ZNF79	7633	zinc finger protein 79	metal ion binding	Molecular function	-
CHCHD3	54927	coiled-coil-helix-coiled-coil-helix domain containing 3	phosphatase binding	Molecular function	19389623
HNF1B	6928	HNF1 homeobox B	regulation of Wnt signaling pathway	Biological process	-
SMEK2	57223	SMEK homolog 2, suppressor of mek1 (Dictyostelium)	protein phosphatase 4 complex	Cellular component	-
AVEN	57099	apoptosis, caspase activation inhibitor	apoptotic process	Biological process	-
CTNNA1	1495	catenin (cadherin-associated protein), alpha 1, 102kDa	negative regulation of cell motility	Biological process	-
AKT1	207	v-akt murine thymoma viral oncogene homolog 1	phosphatidylinositol-mediated signaling	Biological process	-
NPHP3	27031	nephronophthisis 3 (adolescent)	kidney morphogenesis	Biological process	18371931
ALDH9A1	223	aldehyde dehydrogenase 9 family, member A1	aminobutyraldehyde dehydrogenase activity	Molecular function	2925663
CILP	8483	cartilage intermediate layer protein, nucleotide pyrophosphohydrolase	extracellular exosome	Cellular component	23533145
MTOR	2475	mechanistic target of rapamycin (serine/threonine kinase)	cell cycle arrest	Biological process	-
KAT8	84148	K(lysine) acetyltransferase 8	histone H4-K5 acetylation	Biological process	20018852
WNT7B	7477	wingless-type MMTV integration site family, member 7B	fibroblast proliferation	Biological process	19734317
CAPNS2	84290	calpain, small subunit 2	calcium ion binding	Molecular function	-
DRD2	1813	dopamine receptor D2	positive regulation of long-term synaptic potentiation	Biological process	-
AQP4	361	aquaporin 4	plasma membrane	Cellular component	-
EIF4G3	8672	eukaryotic translation initiation factor 4 gamma, 3	translation factor activity, RNA binding	Molecular function	9418880
NPY2R	4887	neuropeptide Y receptor Y2	negative regulation of synaptic transmission, glutamatergic	Biological process	-
TP53	7157	tumor protein p53	positive regulation of cardiac muscle cell apoptotic process	Biological process	-
ARL2	402	ADP-ribosylation factor-like 2	tubulin complex assembly	Biological process	10831612
NUFIP1	26747	nuclear fragile X mental retardation protein interacting protein 1	box C/D snoRNP assembly	Biological process	17636026
DVL2	1856	dishevelled segment polarity protein 2	clathrin-coated endocytic vesicle	Cellular component	-
NKX2-8	26257	NK2 homeobox 8	lung development	Biological process	-
DRD2	1813	dopamine receptor D2	neuron-neuron synaptic transmission	Biological process	-
PKD2L1	9033	polycystic kidney disease 2-like 1	receptor complex	Cellular component	-
AGFG1	3267	ArfGAP with FG repeats 1	metal ion binding	Molecular function	-
RPL10A	4736	ribosomal protein L10a	translation	Biological process	-
HSD17B13	345275	hydroxysteroid (17-beta) dehydrogenase 13	positive regulation of lipid biosynthetic process	Biological process	25028495
ATP6V1B2	526	ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2	proton-transporting V-type ATPase, V1 domain	Cellular component	-
ABCB7	22	ATP-binding cassette, sub-family B (MDR/TAP), member 7	ATPase activity, coupled to transmembrane movement of substances	Molecular function	-
CHD3	1107	chromodomain helicase DNA binding protein 3	chromatin modification	Biological process	-
RDH12	145226	retinol dehydrogenase 12 (all-trans/9-cis/11-cis)	photoreceptor cell maintenance	Biological process	12226107
MYBPC3	4607	myosin binding protein C, cardiac	A band	Cellular component	10024460
PTGR1	22949	prostaglandin reductase 1	extracellular exosome	Cellular component	19056867
C15orf48	84419	chromosome 15 open reading frame 48	nucleus	Cellular component	12209954
ENTPD2	954	ectonucleoside triphosphate diphosphohydrolase 2	integral component of membrane	Cellular component	-
RIMS2	9699	regulating synaptic membrane exocytosis 2	calcium ion-dependent exocytosis of neurotransmitter	Biological process	-
CDHR2	54825	cadherin-related family member 2	apical plasma membrane	Cellular component	-
VEZT	55591	vezatin, adherens junctions transmembrane protein	chordate embryonic development	Biological process	-
LMX1B	4010	LIM homeobox transcription factor 1, beta	midbrain development	Biological process	-
CDK5RAP1	51654	CDK5 regulatory subunit associated protein 1	metal ion binding	Molecular function	-
DDX6	1656	DEAD (Asp-Glu-Ala-Asp) box helicase 6	RNA secondary structure unwinding	Biological process	-
INTS6	26512	integrator complex subunit 6	integrator complex	Cellular component	16239144
ATP6AP1	537	ATPase, H+ transporting, lysosomal accessory protein 1	ion transmembrane transport	Biological process	-
TBC1D10A	83874	TBC1 domain family, member 10A	positive regulation of proteolysis	Biological process	18387192
FGF21	26291	fibroblast growth factor 21	positive regulation of ERK1 and ERK2 cascade	Biological process	17623664
CD200R1	131450	CD200 receptor 1	protein binding	Molecular function	21982860
CHMP2A	27243	charged multivesicular body protein 2A	negative regulation of centriole elongation	Biological process	20616062
DAB2	1601	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)	negative regulation of canonical Wnt signaling pathway	Biological process	12805222
XRCC3	7517	X-ray repair complementing defective repair in Chinese hamster cells 3	response to organic substance	Biological process	-
AHSG	197	alpha-2-HS-glycoprotein	skeletal system development	Biological process	12153747
ABL1	25	ABL proto-oncogene 1, non-receptor tyrosine kinase	activated T cell proliferation	Biological process	-
PIWIL4	143689	piwi-like RNA-mediated gene silencing 4	spermatogenesis	Biological process	-
SLC46A2	57864	solute carrier family 46, member 2	regulation of T cell differentiation	Biological process	-
PTGS1	5742	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	photoreceptor outer segment	Cellular component	-
CTGF	1490	connective tissue growth factor	positive regulation of stress fiber assembly	Biological process	20008146
MSH2	4436	mutS homolog 2	DNA binding	Molecular function	7923193
RPS25	6230	ribosomal protein S25	viral process	Biological process	-
C1QBP	708	complement component 1, q subcomponent binding protein	positive regulation of protein kinase B signaling	Biological process	16177118
ASPA	443	aspartoacylase	aspartoacylase activity	Molecular function	-
ENPP1	5167	ectonucleotide pyrophosphatase/phosphodiesterase 1	nucleic acid binding	Molecular function	-
THBS2	7058	thrombospondin 2	calcium ion binding	Molecular function	-
FNBP1	23048	formin binding protein 1	identical protein binding	Molecular function	15252009
RRP8	23378	ribosomal RNA processing 8, methyltransferase, homolog (yeast)	chromatin silencing at rDNA	Biological process	-
GUCY2C	2984	guanylate cyclase 2C	cGMP biosynthetic process	Biological process	-
NABP1	64859	nucleic acid binding protein 1	SOSS complex	Cellular component	18449195
PIK3CG	5294	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	ephrin receptor binding	Molecular function	11416136
TFAP2B	7021	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	response to drug	Biological process	-
NR2E1	7101	nuclear receptor subfamily 2, group E, member 1	nervous system development	Biological process	9628820
NUDT16	131870	nudix (nucleoside diphosphate linked moiety X)-type motif 16	dITP catabolic process	Biological process	-
RILP	83547	Rab interacting lysosomal protein	protein binding	Molecular function	17010938
CBL	867	Cbl proto-oncogene, E3 ubiquitin protein ligase	negative regulation of apoptotic process	Biological process	18070883
ISG20	3669	interferon stimulated exonuclease gene 20kDa	type I interferon signaling pathway	Biological process	-
RUNX2	860	runt-related transcription factor 2	embryonic cranial skeleton morphogenesis	Biological process	-
GMNN	51053	geminin, DNA replication inhibitor	mitotic cell cycle	Biological process	-
REST	5978	RE1-silencing transcription factor	negative regulation of neurogenesis	Biological process	-
HCK	3055	HCK proto-oncogene, Src family tyrosine kinase	positive regulation of actin cytoskeleton reorganization	Biological process	11904303
PFKFB4	5210	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4	fructose 2,6-bisphosphate metabolic process	Biological process	-
WFS1	7466	Wolfram syndrome 1 (wolframin)	sensory perception of sound	Biological process	17492394
LGI1	9211	leucine-rich, glioma inactivated 1	positive regulation of synaptic transmission	Biological process	-
DAB2IP	153090	DAB2 interacting protein	I-kappaB phosphorylation	Biological process	-
EREG	2069	epiregulin	extracellular space	Cellular component	14581411
ANKRD37	353322	ankyrin repeat domain 37	cytoplasm	Cellular component	-
PKP3	11187	plakophilin 3	cell-cell junction	Cellular component	10374265
CYP1B1	1545	cytochrome P450, family 1, subfamily B, polypeptide 1	iron ion binding	Molecular function	-
KCND1	3750	potassium channel, voltage gated Shal related subfamily D, member 1	regulation of ion transmembrane transport	Biological process	-
PID1	55022	phosphotyrosine interaction domain containing 1	nucleoplasm	Cellular component	-
LIG4	3981	ligase IV, DNA, ATP-dependent	T cell differentiation in thymus	Biological process	-
GHRL	51738	ghrelin/obestatin prepropeptide	positive regulation of cortisol secretion	Biological process	12566947
ZNF780B	163131	zinc finger protein 780B	DNA binding	Molecular function	-
EZR	7430	ezrin	phosphatidylinositol-mediated signaling	Biological process	25591774
SGK2	10110	serum/glucocorticoid regulated kinase 2	protein phosphorylation	Biological process	12397388
ALDH2	217	aldehyde dehydrogenase 2 family (mitochondrial)	alcohol metabolic process	Biological process	1306115
AQP10	89872	aquaporin 10	urea transmembrane transport	Biological process	-
GLS	2744	glutaminase	mitochondrion	Cellular component	10719215
TRAPPC8	22878	trafficking protein particle complex 8	nucleophagy	Biological process	-
ADCY10	55811	adenylate cyclase 10 (soluble)	perinuclear region of cytoplasm	Cellular component	-
RSPO2	340419	R-spondin 2	epithelial tube branching involved in lung morphogenesis	Biological process	-
FKTN	2218	fukutin	negative regulation of cell proliferation	Biological process	18808525
LSR	51599	lipolysis stimulated lipoprotein receptor	integral component of membrane	Cellular component	-
KIF22	3835	kinesin family member 22	sister chromatid cohesion	Biological process	15843429
GPRC5B	51704	G protein-coupled receptor, class C, group 5, member B	nucleus	Cellular component	-
MREG	55686	melanoregulin	apical plasma membrane	Cellular component	-
TMX3	54495	thioredoxin-related transmembrane protein 3	protein folding	Biological process	-
OIP5	11339	Opa interacting protein 5	protein binding	Molecular function	12620389
ENDOG	2021	endonuclease G	in utero embryonic development	Biological process	-
POLE	5426	polymerase (DNA directed), epsilon, catalytic subunit	base-excision repair, gap-filling	Biological process	10559260
F3	2152	coagulation factor III (thromboplastin, tissue factor)	activation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	17898544
MYL6	4637	myosin, light chain 6, alkali, smooth muscle and non-muscle	unconventional myosin complex	Cellular component	2304459
ZNF480	147657	zinc finger protein 480	cytoplasm	Cellular component	-
SMG6	23293	SMG6 nonsense mediated mRNA decay factor	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Biological process	16488880
XCL1	6375	chemokine (C motif) ligand 1	mature natural killer cell chemotaxis	Biological process	9029087
ITGA3	3675	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	positive regulation of cell-substrate adhesion	Biological process	-
TSTD1	100131187	thiosulfate sulfurtransferase (rhodanese)-like domain containing 1	cytoplasm	Cellular component	12817473
SEC24A	10802	SEC24 family member A	positive regulation of protein secretion	Biological process	-
AZIN2	113451	antizyme inhibitor 2	agmatine biosynthetic process	Biological process	-
SNCAIP	9627	synuclein, alpha interacting protein	dopamine metabolic process	Biological process	14506261
NSMCE1	197370	non-SMC element 1 homolog (S. cerevisiae)	intracellular signal transduction	Biological process	-
BCL2	596	B-cell CLL/lymphoma 2	endoplasmic reticulum	Cellular component	8402648
ALG5	29880	ALG5, dolichyl-phosphate beta-glucosyltransferase	protein glycosylation	Biological process	10359825
VAMP3	9341	vesicle-associated membrane protein 3	cell surface	Cellular component	-
MAPK14	1432	mitogen-activated protein kinase 14	signal transduction	Biological process	10706854
BCL2	596	B-cell CLL/lymphoma 2	cellular response to hypoxia	Biological process	-
LMLN	89782	leishmanolysin-like (metallopeptidase M8 family)	metal ion binding	Molecular function	-
RALA	5898	v-ral simian leukemia viral oncogene homolog A (ras related)	exocytosis	Biological process	-
NOD2	64127	nucleotide-binding oligomerization domain containing 2	detection of muramyl dipeptide	Biological process	12527755
ACSL3	2181	acyl-CoA synthetase long-chain family member 3	positive regulation of secretion	Biological process	18003621
PLA2G4C	8605	phospholipase A2, group IVC (cytosolic, calcium-independent)	arachidonic acid metabolic process	Biological process	10085124
SRF	6722	serum response factor (c-fos serum response element-binding transcription factor)	primitive streak formation	Biological process	-
SUFU	51684	suppressor of fused homolog (Drosophila)	nucleoplasm	Cellular component	-
MAPK11	5600	mitogen-activated protein kinase 11	Ras protein signal transduction	Biological process	-
BAG4	9530	BCL2-associated athanogene 4	positive regulation of peptidyl-serine phosphorylation	Biological process	-
CREB3	10488	cAMP responsive element binding protein 3	response to endoplasmic reticulum stress	Biological process	15845366
MFNG	4242	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	integral component of Golgi membrane	Cellular component	-
LAX1	54900	lymphocyte transmembrane adaptor 1	plasma membrane	Cellular component	-
ZNF840P	100130863	zinc finger protein 840, pseudogene	metal ion binding	Molecular function	-
SLC4A5	57835	solute carrier family 4 (sodium bicarbonate cotransporter), member 5	anion transmembrane transport	Biological process	-
GDF2	2658	growth differentiation factor 2	positive regulation of BMP signaling pathway	Biological process	-
INPP5B	3633	inositol polyphosphate-5-phosphatase, 75kDa	small molecule metabolic process	Biological process	-
CD3E	916	CD3e molecule, epsilon (CD3-TCR complex)	regulation of immune response	Biological process	-
FCRL3	115352	Fc receptor-like 3	plasma membrane	Cellular component	-
SH3GLB1	51100	SH3-domain GRB2-like endophilin B1	cellular response to glucose starvation	Biological process	21068542
RIC3	79608	RIC3 acetylcholine receptor chaperone	integral component of membrane	Cellular component	-
SYVN1	84447	synovial apoptosis inhibitor 1, synoviolin	protein ubiquitination	Biological process	23710284
GCFC2	6936	GC-rich sequence DNA-binding factor 2	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	9705290
PGR	5241	progesterone receptor	tertiary branching involved in mammary gland duct morphogenesis	Biological process	-
CNGB3	54714	cyclic nucleotide gated channel beta 3	integral component of plasma membrane	Cellular component	-
CTTN	2017	cortactin	dendritic spine maintenance	Biological process	-
HSD17B4	3295	hydroxysteroid (17-beta) dehydrogenase 4	receptor binding	Molecular function	20178365
ENPP2	5168	ectonucleotide pyrophosphatase/phosphodiesterase 2	immune response	Biological process	-
BDNF	627	brain-derived neurotrophic factor	response to fluoxetine	Biological process	-
ATL1	51062	atlastin GTPase 1	GTP binding	Molecular function	-
VAMP7	6845	vesicle-associated membrane protein 7	secretory granule membrane	Cellular component	16677249
RHOXF1	158800	Rhox homeobox family, member 1	regulation of transcription, DNA-templated	Biological process	11980563
CD53	963	CD53 molecule	cell surface	Cellular component	-
SLC39A7	7922	solute carrier family 39 (zinc transporter), member 7	Golgi apparatus	Cellular component	-
NOD2	64127	nucleotide-binding oligomerization domain containing 2	MyD88-independent toll-like receptor signaling pathway	Biological process	-
TICAM2	353376	toll-like receptor adaptor molecule 2	TRIF-dependent toll-like receptor signaling pathway	Biological process	-
SEMA5A	9037	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	cell chemotaxis	Biological process	-
CANX	821	calnexin	calcium ion binding	Molecular function	-
ARRB1	408	arrestin, beta 1	GTPase activator activity	Molecular function	15611106
KMT2E	55904	lysine (K)-specific methyltransferase 2E	cellular response to retinoic acid	Biological process	-
WNT10A	80326	wingless-type MMTV integration site family, member 10A	positive regulation of gene expression	Biological process	-
SPINK7	84651	serine peptidase inhibitor, Kazal type 7 (putative)	protein binding	Molecular function	12646258
DIS3L2	129563	DIS3 like 3'-5' exoribonuclease 2	3'-5'-exoribonuclease activity	Molecular function	23756462
SMAP1	60682	small ArfGAP 1	plasma membrane	Cellular component	-
CA5B	11238	carbonic anhydrase VB, mitochondrial	mitochondrial matrix	Cellular component	-
CDH18	1016	cadherin 18, type 2	plasma membrane	Cellular component	-
RAB11A	8766	RAB11A, member RAS oncogene family	regulation of multivesicular body size	Biological process	15634213
IRF5	3663	interferon regulatory factor 5	interferon-gamma-mediated signaling pathway	Biological process	-
VPS11	55823	vacuolar protein sorting 11 homolog (S. cerevisiae)	lysosome	Cellular component	21148287
KAT6A	7994	K(lysine) acetyltransferase 6A	MOZ/MORF histone acetyltransferase complex	Cellular component	16387653
CTDP1	9150	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1	viral process	Biological process	-
CRHBP	1393	corticotropin releasing hormone binding protein	behavioral response to ethanol	Biological process	21039637
PFKL	5211	phosphofructokinase, liver	small molecule metabolic process	Biological process	-
KCNN4	3783	potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4	small conductance calcium-activated potassium channel activity	Molecular function	-
HUS1	3364	HUS1 checkpoint homolog (S. pombe)	cellular response to ionizing radiation	Biological process	21659603
LGALS1	3956	lectin, galactoside-binding, soluble, 1	cellular response to organic cyclic compound	Biological process	-
PCOLCE	5118	procollagen C-endopeptidase enhancer	multicellular organismal development	Biological process	7523404
WFS1	7466	Wolfram syndrome 1 (wolframin)	IRE1-mediated unfolded protein response	Biological process	-
ACVR2A	92	activin A receptor, type IIA	spermatogenesis	Biological process	-
PRDM5	11107	PR domain containing 5	protein binding	Molecular function	17636019
SRPX2	27286	sushi-repeat containing protein, X-linked 2	positive regulation of cell migration involved in sprouting angiogenesis	Biological process	-
FOXP2	93986	forkhead box P2	vocal learning	Biological process	-
MTHFR	4524	methylenetetrahydrofolate reductase (NAD(P)H)	folic acid metabolic process	Biological process	-
ASCL1	429	achaete-scute family bHLH transcription factor 1	response to folic acid	Biological process	-
CYP24A1	1591	cytochrome P450, family 24, subfamily A, polypeptide 1	iron ion binding	Molecular function	-
SRSF5	6430	serine/arginine-rich splicing factor 5	RNA splicing	Biological process	-
OR8S1	341568	olfactory receptor, family 8, subfamily S, member 1	integral component of membrane	Cellular component	-
SRCIN1	80725	SRC kinase signaling inhibitor 1	axon	Cellular component	-
ALKBH4	54784	alkB, alkylation repair homolog 4 (E. coli)	protein binding	Molecular function	21516116
PGM2	55276	phosphoglucomutase 2	phosphoglucomutase activity	Molecular function	-
MCM7	4176	minichromosome maintenance complex component 7	cell proliferation	Biological process	-
POU2F3	25833	POU class 2 homeobox 3	wound healing	Biological process	-
CAMK2D	817	calcium/calmodulin-dependent protein kinase II delta	peptidyl-serine phosphorylation	Biological process	22514276
CALCOCO2	10241	calcium binding and coiled-coil domain 2	cytoplasm	Cellular component	-
GZMB	3002	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	serine-type endopeptidase activity	Molecular function	12524539
AHR	196	aryl hydrocarbon receptor	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
MAP2K7	5609	mitogen-activated protein kinase kinase 7	TRIF-dependent toll-like receptor signaling pathway	Biological process	-
HDAC5	10014	histone deacetylase 5	histone deacetylase complex	Cellular component	12711221
COMP	1311	cartilage oligomeric matrix protein	growth plate cartilage development	Biological process	-
SDCBP2	27111	syndecan binding protein (syntenin) 2	intracellular transport	Biological process	11152476
CCR2	729230	chemokine (C-C motif) receptor 2	JAK-STAT cascade	Biological process	9670957
SPRR2D	6703	small proline-rich protein 2D	keratinization	Biological process	-
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	embryonic digit morphogenesis	Biological process	-
TP53	7157	tumor protein p53	oligodendrocyte apoptotic process	Biological process	7720704
CNTLN	54875	centlein, centrosomal protein	signal transduction by protein phosphorylation	Biological process	-
TGFB2	7042	transforming growth factor, beta 2	negative regulation of immune response	Biological process	9611771
SLC16A3	9123	solute carrier family 16 (monocarboxylate transporter), member 3	protein binding	Molecular function	25416956
SPATA9	83890	spermatogenesis associated 9	integral component of membrane	Cellular component	-
SNAP47	116841	synaptosomal-associated protein, 47kDa	perinuclear region of cytoplasm	Cellular component	-
GNA13	10672	guanine nucleotide binding protein (G protein), alpha 13	regulation of cell migration	Biological process	-
GALC	2581	galactosylceramidase	sphingolipid metabolic process	Biological process	-
ITPR3	3710	inositol 1,4,5-trisphosphate receptor, type 3	nucleolus	Cellular component	-
HAGH	3029	hydroxyacylglutathione hydrolase	extracellular exosome	Cellular component	23376485
CYP26A1	1592	cytochrome P450, family 26, subfamily A, polypeptide 1	oxygen binding	Molecular function	9228017
GABARAPL3	23766	GABA(A) receptors associated protein like 3, pseudogene	cytoplasmic vesicle	Cellular component	-
RPS6KA3	6197	ribosomal protein S6 kinase, 90kDa, polypeptide 3	central nervous system development	Biological process	10319851
CAMK2B	816	calcium/calmodulin-dependent protein kinase II beta	regulation of skeletal muscle adaptation	Biological process	15294044
ASF1A	25842	anti-silencing function 1A histone chaperone	protein complex	Cellular component	14718166
OR11H1	81061	olfactory receptor, family 11, subfamily H, member 1	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
PARK7	11315	parkinson protein 7	mRNA binding	Molecular function	18626009
MYBBP1A	10514	MYB binding protein (P160) 1a	transcription corepressor activity	Molecular function	-
SLC6A2	6530	solute carrier family 6 (neurotransmitter transporter), member 2	norepinephrine transport	Biological process	-
CD46	4179	CD46 molecule, complement regulatory protein	inner acrosomal membrane	Cellular component	-
COL4A2	1284	collagen, type IV, alpha 2	cellular response to transforming growth factor beta stimulus	Biological process	-
TXNDC15	79770	thioredoxin domain containing 15	integral component of membrane	Cellular component	-
TRAF2	7186	TNF receptor-associated factor 2	signal transducer activity	Molecular function	8702708
CHMP2B	25978	charged multivesicular body protein 2B	vacuolar transport	Biological process	-
IL13RA1	3597	interleukin 13 receptor, alpha 1	positive regulation of B cell proliferation	Biological process	-
LMO2	4005	LIM domain only 2 (rhombotin-like 1)	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	16314316
DEFB106A	245909	defensin, beta 106A	cell surface	Cellular component	-
PTGFR	5737	prostaglandin F receptor (FP)	negative regulation of apoptotic process	Biological process	-
FOXP2	93986	forkhead box P2	positive regulation of epithelial cell proliferation involved in lung morphogenesis	Biological process	-
TIRAP	114609	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	response to lipopolysaccharide	Biological process	11544529
TAS2R16	50833	taste receptor, type 2, member 16	G-protein coupled receptor signaling pathway	Biological process	16720576
ATP6V0A2	23545	ATPase, H+ transporting, lysosomal V0 subunit a2	phagosome maturation	Biological process	-
PTTG1	9232	pituitary tumor-transforming 1	mitotic cell cycle	Biological process	-
ZNF268	10795	zinc finger protein 268	sequence-specific DNA binding transcription factor activity	Molecular function	11311945
HSD17B6	8630	hydroxysteroid (17-beta) dehydrogenase 6	endoplasmic reticulum	Cellular component	-
ADCY4	196883	adenylate cyclase 4	ATP binding	Molecular function	-
CCL3	6348	chemokine (C-C motif) ligand 3	chemotaxis	Biological process	10679098
EZR	7430	ezrin	membrane raft	Cellular component	-
DYNLRB1	83658	dynein, light chain, roadblock-type 1	microtubule	Cellular component	-
NTRK1	4914	neurotrophic tyrosine kinase, receptor, type 1	neurotrophin p75 receptor binding	Molecular function	-
ESR2	2100	estrogen receptor 2 (ER beta)	steroid binding	Molecular function	11181953
ISL1	3670	ISL LIM homeobox 1	ventricular cardiac muscle tissue morphogenesis	Biological process	-
RAB3B	5865	RAB3B, member RAS oncogene family	intracellular protein transport	Biological process	-
GYS1	2997	glycogen synthase 1 (muscle)	protein kinase binding	Molecular function	16275910
SLC6A4	6532	solute carrier family 6 (neurotransmitter transporter), member 4	cocaine binding	Molecular function	-
SPI1	6688	Spi-1 proto-oncogene	protein binding	Molecular function	10207087
ICAM2	3384	intercellular adhesion molecule 2	cell adhesion	Biological process	-
RELN	5649	reelin	positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity	Biological process	-
PRKD1	5587	protein kinase D1	cell cortex	Cellular component	-
ARHGEF25	115557	Rho guanine nucleotide exchange factor (GEF) 25	myofibril	Cellular component	-
STXBP5L	9515	syntaxin binding protein 5-like	glucose homeostasis	Biological process	-
TGFB1I1	7041	transforming growth factor beta 1 induced transcript 1	ubiquitin-dependent SMAD protein catabolic process	Biological process	18762808
BIRC8	112401	baculoviral IAP repeat containing 8	scaffold protein binding	Molecular function	-
RXRG	6258	retinoid X receptor, gamma	RNA polymerase II regulatory region sequence-specific DNA binding	Molecular function	-
SET	6418	SET nuclear proto-oncogene	protein phosphatase type 2A regulator activity	Molecular function	11555662
ACER2	340485	alkaline ceramidase 2	positive regulation of cell death	Biological process	20628055
CBFA2T3	863	core-binding factor, runt domain, alpha subunit 2; translocated to, 3	negative regulation of transcription, DNA-templated	Biological process	-
SCNN1A	6337	sodium channel, non voltage gated 1 alpha subunit	extracellular exosome	Cellular component	15326289
SLC38A5	92745	solute carrier family 38, member 5	plasma membrane	Cellular component	-
BCL2L1	598	BCL2-like 1	response to cycloheximide	Biological process	-
PSMC4	5704	proteasome (prosome, macropain) 26S subunit, ATPase, 4	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	Biological process	-
C20orf27	54976	chromosome 20 open reading frame 27	cellular_component	Cellular component	-
DSCR4	10281	Down syndrome critical region 4	molecular_function	Molecular function	-
ING4	51147	inhibitor of growth family, member 4	negative regulation of cell proliferation	Biological process	12750254
UNC119	9094	unc-119 homolog (C. elegans)	synaptic transmission	Biological process	9538874
KANSL3	55683	KAT8 regulatory NSL complex subunit 3	histone H4-K16 acetylation	Biological process	20018852
RFC4	5984	replication factor C (activator 1) 4, 37kDa	DNA replication factor C complex	Cellular component	9488738
SMAD3	4088	SMAD family member 3	identical protein binding	Molecular function	18729074
PLA2G5	5322	phospholipase A2, group V	extracellular region	Cellular component	-
C6orf25	80739	chromosome 6 open reading frame 25	Golgi apparatus	Cellular component	-
S1PR1	1901	sphingosine-1-phosphate receptor 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
ROCK2	9475	Rho-associated, coiled-coil containing protein kinase 2	structural molecule activity	Molecular function	9933571
PDGFRA	5156	platelet-derived growth factor receptor, alpha polypeptide	extracellular matrix organization	Biological process	-
CD300LD	100131439	CD300 molecule-like family member d	integral component of membrane	Cellular component	-
PLA2G1B	5319	phospholipase A2, group IB (pancreas)	cell surface	Cellular component	1918029
SLC17A5	26503	solute carrier family 17 (acidic sugar transporter), member 5	lysosomal membrane	Cellular component	-
SMARCA1	6594	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1	nucleosome-dependent ATPase activity	Molecular function	15640247
ENC1	8507	ectodermal-neural cortex 1 (with BTB domain)	Cul3-RING ubiquitin ligase complex	Cellular component	15983046
CSRP2	1466	cysteine and glycine-rich protein 2	molecular_function	Molecular function	-
NLRC4	58484	NLR family, CARD domain containing 4	ATP binding	Molecular function	15882992
KLHL3	26249	kelch-like family member 3	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	23453970
CNTNAP2	26047	contactin associated protein-like 2	perikaryon	Cellular component	-
MCM10	55388	minichromosome maintenance complex component 10	DNA replication initiation	Biological process	-
SLC11A2	4891	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2	zinc II ion transmembrane transport	Biological process	17109629
UNC93B1	81622	unc-93 homolog B1 (C. elegans)	toll-like receptor 7 signaling pathway	Biological process	19006693
ORC6	23594	origin recognition complex, subunit 6	nuclear origin of replication recognition complex	Cellular component	-
SUGP2	10147	SURP and G patch domain containing 2	poly(A) RNA binding	Molecular function	22658674
RASSF2	9770	Ras association (RalGDS/AF-6) domain family member 2	skeletal system development	Biological process	-
STYXL1	51657	serine/threonine/tyrosine interacting-like 1	intracellular signal transduction	Biological process	9757831
TAF6	6878	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa	DNA binding	Molecular function	15601843
PTBP1	5725	polypyrimidine tract binding protein 1	negative regulation of RNA splicing	Biological process	18335065
PPP1R16B	26051	protein phosphatase 1, regulatory subunit 16B	negative regulation of peptidyl-serine dephosphorylation	Biological process	25007873
ELMOD2	255520	ELMO/CED-12 domain containing 2	regulation of defense response to virus	Biological process	17452337
RNF6	6049	ring finger protein (C3H2C3 type) 6	axon	Cellular component	-
DRD1	1812	dopamine receptor D1	response to drug	Biological process	-
CYP2J2	1573	cytochrome P450, family 2, subfamily J, polypeptide 2	linoleic acid epoxygenase activity	Molecular function	11901223
DPYSL2	1808	dihydropyrimidinase-like 2	nervous system development	Biological process	8973361
FGFR3	2261	fibroblast growth factor receptor 3	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway	Biological process	-
TIAM1	7074	T-cell lymphoma invasion and metastasis 1	extrinsic component of cytoplasmic side of plasma membrane	Cellular component	20361982
FGF7	2252	fibroblast growth factor 7	innate immune response	Biological process	-
SLC16A3	9123	solute carrier family 16 (monocarboxylate transporter), member 3	leukocyte migration	Biological process	-
NKX3-2	579	NK3 homeobox 2	skeletal system morphogenesis	Biological process	-
SLC1A2	6506	solute carrier family 1 (glial high affinity glutamate transporter), member 2	glutamate:sodium symporter activity	Molecular function	-
MYO1A	4640	myosin IA	microvillus	Cellular component	9858156
CLU	1191	clusterin	endoplasmic reticulum	Cellular component	-
P2RY2	5029	purinergic receptor P2Y, G-protein coupled, 2	positive regulation of mucus secretion	Biological process	-
FZD5	7855	frizzled class receptor 5	Spemann organizer formation	Biological process	9054360
TNFSF13B	10673	tumor necrosis factor (ligand) superfamily, member 13b	perinuclear region of cytoplasm	Cellular component	19828625
FCER1A	2205	Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide	cell surface	Cellular component	1535625
VAV3	10451	vav 3 guanine nucleotide exchange factor	B cell receptor signaling pathway	Biological process	17875758
PGM2	55276	phosphoglucomutase 2	carbohydrate metabolic process	Biological process	-
CHEK1	1111	checkpoint kinase 1	replicative senescence	Biological process	15149599
GP6	51206	glycoprotein VI (platelet)	receptor activity	Molecular function	11027634
HNF1A	6927	HNF1 homeobox A	DNA binding	Molecular function	10333057
DDX3Y	8653	DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked	membrane	Cellular component	19946888
FCGR1A	2209	Fc fragment of IgG, high affinity Ia, receptor (CD64)	phagocytosis, engulfment	Biological process	10879688
UBIAD1	29914	UbiA prenyltransferase domain containing 1	antioxidant activity	Molecular function	23374346
TBL1Y	90665	transducin (beta)-like 1, Y-linked	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological process	-
GJA1	2697	gap junction protein, alpha 1, 43kDa	positive regulation of vasoconstriction	Biological process	-
TBCD	6904	tubulin folding cofactor D	tubulin complex biogenesis	Biological process	-
ODC1	4953	ornithine decarboxylase 1	polyamine metabolic process	Biological process	-
PITPNM2	57605	phosphatidylinositol transfer protein, membrane-associated 2	lipid binding	Molecular function	-
SRCAP	10847	Snf2-related CREBBP activator protein	Golgi apparatus	Cellular component	-
GRK1	6011	G protein-coupled receptor kinase 1	protein kinase activity	Molecular function	1656454
HAUS1	115106	HAUS augmin-like complex, subunit 1	centrosome organization	Biological process	19427217
GGT1	2678	gamma-glutamyltransferase 1	xenobiotic metabolic process	Biological process	-
HIRA	7290	histone cell cycle regulator	regulation of transcription from RNA polymerase II promoter	Biological process	9731536
OVOL2	58495	ovo-like zinc finger 2	epidermal cell differentiation	Biological process	-
SLC16A9	220963	solute carrier family 16, member 9	monocarboxylic acid transmembrane transporter activity	Molecular function	-
PREX1	57580	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	protein binding	Molecular function	17565979
GATA4	2626	GATA binding protein 4	regulation of transcription, DNA-templated	Biological process	-
UPF2	26019	UPF2 regulator of nonsense transcripts homolog (yeast)	nucleus	Cellular component	14636577
SMURF1	57154	SMAD specific E3 ubiquitin protein ligase 1	cytoplasm	Cellular component	11278251
H3F3C	440093	H3 histone, family 3C	protein binding	Molecular function	25416956
PSMA6	5687	proteasome (prosome, macropain) subunit, alpha type, 6	protein binding	Molecular function	14733938
MRPL41	64975	mitochondrial ribosomal protein L41	mitochondrial inner membrane	Cellular component	-
CHD8	57680	chromodomain helicase DNA binding protein 8	armadillo repeat domain binding	Molecular function	-
PLA2G12B	84647	phospholipase A2, group XIIB	extracellular region	Cellular component	-
NCOA1	8648	nuclear receptor coactivator 1	positive regulation of apoptotic process	Biological process	-
WNT10B	7480	wingless-type MMTV integration site family, member 10B	protein stabilization	Biological process	10937998
HEXA	3073	hexosaminidase A (alpha polypeptide)	hyaluronan metabolic process	Biological process	-
SOCS6	9306	suppressor of cytokine signaling 6	cytoplasm	Cellular component	9344848
RAG1	5896	recombination activating gene 1	histone binding	Molecular function	-
COX15	1355	cytochrome c oxidase assembly homolog 15 (yeast)	cellular respiration	Biological process	12474143
SUPT5H	6829	suppressor of Ty 5 homolog (S. cerevisiae)	protein binding	Molecular function	10075709
TLX1	3195	T-cell leukemia homeobox 1	protein heterodimerization activity	Molecular function	-
TRAF4	9618	TNF receptor-associated factor 4	DNA binding	Molecular function	7592751
SMARCB1	6598	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	DNA integration	Biological process	7801128
CADM1	23705	cell adhesion molecule 1	dendrite	Cellular component	-
NFKBIE	4794	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	cytosol	Cellular component	-
NCK1	4690	NCK adaptor protein 1	vesicle membrane	Cellular component	-
TMEM234	56063	transmembrane protein 234	protein binding	Molecular function	25416956
GBP6	163351	guanylate binding protein family, member 6	metabolic process	Biological process	-
STMN2	11075	stathmin 2	neuronal cell body	Cellular component	21215777
ILK	3611	integrin-linked kinase	platelet aggregation	Biological process	23382103
ARRB2	409	arrestin, beta 2	transforming growth factor beta receptor signaling pathway	Biological process	12958365
FZD5	7855	frizzled class receptor 5	positive regulation of transcription from RNA polymerase II promoter	Biological process	10906785
SPICE1	152185	spindle and centriole associated protein 1	centrosome	Cellular component	-
RPA2	6118	replication protein A2, 32kDa	error-free translesion synthesis	Biological process	-
KIF7	374654	kinesin family member 7	ciliary tip	Cellular component	-
SLC25A32	81034	solute carrier family 25 (mitochondrial folate carrier), member 32	folic acid transport	Biological process	10978331
ORC1	4998	origin recognition complex, subunit 1	nuclear origin of replication recognition complex	Cellular component	20932478
ACHE	43	acetylcholinesterase (Yt blood group)	regulation of receptor recycling	Biological process	-
ZFYVE16	9765	zinc finger, FYVE domain containing 16	intracellular membrane-bounded organelle	Cellular component	-
MGAT3	4248	mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase	Golgi membrane	Cellular component	-
PGM1	5236	phosphoglucomutase 1	actin cytoskeleton	Cellular component	-
VPS33B	26276	vacuolar protein sorting 33 homolog B (yeast)	platelet alpha granule organization	Biological process	16123220
NAGLU	4669	N-acetylglucosaminidase, alpha	cerebellar Purkinje cell layer development	Biological process	-
FIS1	51024	fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)	peroxisome	Cellular component	14561759
GAD2	2572	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)	presynaptic membrane	Cellular component	-
EFNA4	1945	ephrin-A4	bone remodeling	Biological process	-
DMPK	1760	dystrophia myotonica-protein kinase	ATP binding	Molecular function	10913253
HGD	3081	homogentisate 1,2-dioxygenase	tyrosine catabolic process	Biological process	-
RFX4	5992	regulatory factor X, 4 (influences HLA class II expression)	dorsal spinal cord development	Biological process	-
CNOT7	29883	CCR4-NOT transcription complex, subunit 7	cytoplasmic mRNA processing body assembly	Biological process	-
NR1D1	9572	nuclear receptor subfamily 1, group D, member 1	gene expression	Biological process	-
CYBA	1535	cytochrome b-245, alpha polypeptide	heme binding	Molecular function	-
EXOC4	60412	exocyst complex component 4	membrane	Cellular component	19946888
GNAI2	2771	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway	Biological process	-
NLN	57486	neurolysin (metallopeptidase M3 family)	metalloendopeptidase activity	Molecular function	-
PLSCR4	57088	phospholipid scramblase 4	CD4 receptor binding	Molecular function	19333378
SLC30A8	169026	solute carrier family 30 (zinc transporter), member 8	regulation of sequestering of zinc ion	Biological process	-
CLCN3	1182	chloride channel, voltage-sensitive 3	cell surface	Cellular component	12471024
SMYD2	56950	SET and MYND domain containing 2	protein binding	Molecular function	20870719
HELT	391723	helt bHLH transcription factor	post-embryonic development	Biological process	-
DMBT1	1755	deleted in malignant brain tumors 1	positive regulation of epithelial cell differentiation	Biological process	-
STAT5A	6776	signal transducer and activator of transcription 5A	creatinine metabolic process	Biological process	-
PCNXL4	64430	pecanex-like 4 (Drosophila)	integral component of membrane	Cellular component	-
HIST1H2BL	8340	histone cluster 1, H2bl	protein heterodimerization activity	Molecular function	-
P2RX1	5023	purinergic receptor P2X, ligand gated ion channel, 1	extracellular ATP-gated cation channel activity	Molecular function	-
ERP44	23071	endoplasmic reticulum protein 44	glycoprotein metabolic process	Biological process	11847130
ANKS1B	56899	ankyrin repeat and sterile alpha motif domain containing 1B	cell junction	Cellular component	-
TRIM40	135644	tripartite motif containing 40	protein neddylation	Biological process	21474709
EIF3H	8667	eukaryotic translation initiation factor 3, subunit H	eukaryotic translation initiation factor 3 complex, eIF3m	Cellular component	-
GATA6	2627	GATA binding protein 6	chromatin binding	Molecular function	-
NSMF	26012	NMDA receptor synaptonuclear signaling and neuronal migration factor	regulation of dendrite morphogenesis	Biological process	-
TOP2B	7155	topoisomerase (DNA) II beta 180kDa	DNA topoisomerase complex (ATP-hydrolyzing)	Cellular component	-
NFE2	4778	nuclear factor, erythroid 2	hemostasis	Biological process	7774011
SAMM50	25813	SAMM50 sorting and assembly machinery component	mitochondrial sorting and assembly machinery complex	Cellular component	15644312
MTMR14	64419	myotubularin related protein 14	phospholipid metabolic process	Biological process	-
C5AR2	27202	complement component 5a receptor 2	negative regulation of tumor necrosis factor production	Biological process	16204243
DLL1	28514	delta-like 1 (Drosophila)	cell fate determination	Biological process	11581320
SREBF2	6721	sterol regulatory element binding transcription factor 2	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	15358760
PAX2	5076	paired box 2	core promoter proximal region sequence-specific DNA binding	Molecular function	19118900
ZNF542P	147947	zinc finger protein 542, pseudogene	metal ion binding	Molecular function	-
CECR2	27443	cat eye syndrome chromosome region, candidate 2	nucleus	Cellular component	12762840
AKAP4	8852	A kinase (PRKA) anchor protein 4	single fertilization	Biological process	9822690
NKX6-1	4825	NK6 homeobox 1	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	-
CEP57	9702	centrosomal protein 57kDa	fibroblast growth factor binding	Molecular function	12717444
PTK2B	2185	protein tyrosine kinase 2 beta	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	-
TRMT6	51605	tRNA methyltransferase 6	tRNA methylation	Biological process	-
PPP1CA	5499	protein phosphatase 1, catalytic subunit, alpha isozyme	protein binding	Molecular function	10807923
COL4A3	1285	collagen, type IV, alpha 3 (Goodpasture antigen)	collagen type IV trimer	Cellular component	10766752
NR4A2	4929	nuclear receptor subfamily 4, group A, member 2	dopamine biosynthetic process	Biological process	-
MUTYH	4595	mutY homolog	protein binding	Molecular function	11801590
DDRGK1	65992	DDRGK domain containing 1	endoplasmic reticulum	Cellular component	20018847
SMURF2	64750	SMAD specific E3 ubiquitin protein ligase 2	regulation of transforming growth factor beta receptor signaling pathway	Biological process	11158580
ABCG4	64137	ATP-binding cassette, sub-family G (WHITE), member 4	metabolic process	Biological process	-
TREM2	54209	triggering receptor expressed on myeloid cells 2	positive regulation of peptidyl-tyrosine phosphorylation	Biological process	11602640
ADRA1A	148	adrenoceptor alpha 1A	positive regulation of cardiac muscle contraction	Biological process	-
PRKCA	5578	protein kinase C, alpha	regulation of rhodopsin mediated signaling pathway	Biological process	-
ABCA10	10349	ATP-binding cassette, sub-family A (ABC1), member 10	intracellular membrane-bounded organelle	Cellular component	-
RAB1A	5861	RAB1A, member RAS oncogene family	GTP binding	Molecular function	-
SNAI1	6615	snail family zinc finger 1	positive regulation of cell migration	Biological process	15314165
STRAP	11171	serine/threonine kinase receptor associated protein	cytoplasm	Cellular component	-
CACNA1D	776	calcium channel, voltage-dependent, L type, alpha 1D subunit	voltage-gated calcium channel activity involved SA node cell action potential	Molecular function	21131953
CDC20	991	cell division cycle 20	protein ubiquitination	Biological process	-
PACSIN2	11252	protein kinase C and casein kinase substrate in neurons 2	extrinsic component of membrane	Cellular component	-
VAMP2	6844	vesicle-associated membrane protein 2 (synaptobrevin 2)	SNARE binding	Molecular function	-
IFNG	3458	interferon, gamma	positive regulation of membrane protein ectodomain proteolysis	Biological process	18373975
TRAF3IP1	26146	TNF receptor-associated factor 3 interacting protein 1	embryonic digit morphogenesis	Biological process	-
PSMA4	5685	proteasome (prosome, macropain) subunit, alpha type, 4	viral process	Biological process	-
TBX6	6911	T-box 6	mesoderm formation	Biological process	-
PHF6	84295	PHD finger protein 6	transcription, DNA-templated	Biological process	-
SLC7A8	23428	solute carrier family 7 (amino acid transporter light chain, L system), member 8	integral component of plasma membrane	Cellular component	10391915
PIAS1	8554	protein inhibitor of activated STAT, 1	PML body	Cellular component	-
PSME2	5721	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)	negative regulation of apoptotic process	Biological process	-
DLGAP2	9228	discs, large (Drosophila) homolog-associated protein 2	postsynaptic membrane	Cellular component	-
SRSF7	6432	serine/arginine-rich splicing factor 7	mRNA 3'-end processing	Biological process	-
AIF1	199	allograft inflammatory factor 1	ruffle assembly	Biological process	17011575
PARD3	56288	par-3 family cell polarity regulator	protein targeting to membrane	Biological process	-
RARA	5914	retinoic acid receptor, alpha	negative regulation of cell proliferation	Biological process	-
TAP1	6890	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	mitochondrion	Cellular component	-
HDAC2	3066	histone deacetylase 2	negative regulation of gene expression, epigenetic	Biological process	-
FOXC2	2303	forkhead box C2	Notch signaling pathway	Biological process	-
KCNC2	3747	potassium channel, voltage gated Shaw related subfamily C, member 2	membrane	Cellular component	-
HSP90AA1	3320	heat shock protein 90kDa alpha (cytosolic), class A member 1	protein phosphatase binding	Molecular function	-
CYP2C19	1557	cytochrome P450, family 2, subfamily C, polypeptide 19	small molecule metabolic process	Biological process	-
PEG10	23089	paternally expressed 10	protein binding	Molecular function	15611116
RGS17	26575	regulator of G-protein signaling 17	termination of G-protein coupled receptor signaling pathway	Biological process	-
LFNG	3955	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	female meiotic division	Biological process	-
RALA	5898	v-ral simian leukemia viral oncogene homolog A (ras related)	GTP binding	Molecular function	24056301
PDX1	3651	pancreatic and duodenal homeobox 1	positive regulation of cell death	Biological process	-
LDLRAP1	26119	low density lipoprotein receptor adaptor protein 1	regulation of establishment of protein localization to plasma membrane	Biological process	12805363
CATSPER1	117144	cation channel, sperm associated 1	ion transmembrane transport	Biological process	-
CLN3	1201	ceroid-lipofuscinosis, neuronal 3	macroautophagy	Biological process	9949212
MGST1	4257	microsomal glutathione S-transferase 1	small molecule metabolic process	Biological process	-
NKD1	85407	naked cuticle homolog 1 (Drosophila)	plasma membrane	Cellular component	-
FAM114A2	10827	family with sequence similarity 114, member A2	purine nucleotide binding	Molecular function	10843801
PYGO2	90780	pygopus family PHD finger 2	chromatin binding	Molecular function	-
RLN2	6019	relaxin 2	regulation of metalloenzyme activity	Biological process	16049981
TRAF6	7189	TNF receptor-associated factor 6, E3 ubiquitin protein ligase	ligase activity	Molecular function	-
NUPL2	11097	nucleoporin like 2	metal ion binding	Molecular function	-
SERPINH1	871	serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)	collagen biosynthetic process	Biological process	-
ADM	133	adrenomedullin	adrenomedullin receptor binding	Molecular function	-
YIPF5	81555	Yip1 domain family, member 5	protein transport	Biological process	-
IL1RAP	3556	interleukin 1 receptor accessory protein	innate immune response	Biological process	-
AADACL2	344752	arylacetamide deacetylase-like 2	carboxylic ester hydrolase activity	Molecular function	-
SLC11A2	4891	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2	membrane	Cellular component	19946888
EIF2AK2	5610	eukaryotic translation initiation factor 2-alpha kinase 2	non-membrane spanning protein tyrosine kinase activity	Molecular function	-
SLC11A1	6556	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1	protein import into nucleus, translocation	Biological process	-
SPX	80763	spexin hormone	long-chain fatty acid import	Biological process	-
SOX9	6662	SRY (sex determining region Y)-box 9	cellular response to transforming growth factor beta stimulus	Biological process	21401405
RNF14	9604	ring finger protein 14	regulation of androgen receptor signaling pathway	Biological process	19345326
IGFBP2	3485	insulin-like growth factor binding protein 2, 36kDa	protein binding	Molecular function	19095771
TMEM182	130827	transmembrane protein 182	integral component of membrane	Cellular component	-
P2RY1	5028	purinergic receptor P2Y, G-protein coupled, 1	positive regulation of ERK1 and ERK2 cascade	Biological process	-
RAB15	376267	RAB15, member RAS oncogene family	endosome membrane	Cellular component	16195351
CD2	914	CD2 molecule	integral component of plasma membrane	Cellular component	7544493
VAMP2	6844	vesicle-associated membrane protein 2 (synaptobrevin 2)	Golgi to plasma membrane protein transport	Biological process	-
WASF2	10163	WAS protein family, member 2	angiogenesis	Biological process	-
NPFF	8620	neuropeptide FF-amide peptide precursor	negative regulation of insulin secretion	Biological process	-
C8A	731	complement component 8, alpha polypeptide	innate immune response	Biological process	-
RHOU	58480	ras homolog family member U	regulation of cell shape	Biological process	21834987
ATP6V0A2	23545	ATPase, H+ transporting, lysosomal V0 subunit a2	cytoplasm	Cellular component	-
SLC25A20	788	solute carrier family 25 (carnitine/acylcarnitine translocase), member 20	mitochondrion	Cellular component	-
ZNF132	7691	zinc finger protein 132	regulation of transcription, DNA-templated	Biological process	-
SUPT4H1	6827	suppressor of Ty 4 homolog 1 (S. cerevisiae)	gene expression	Biological process	-
BTRC	8945	beta-transducin repeat containing E3 ubiquitin protein ligase	circadian rhythm	Biological process	-
FSHB	2488	follicle stimulating hormone, beta polypeptide	regulation of osteoclast differentiation	Biological process	-
MAP1LC3A	84557	microtubule-associated protein 1 light chain 3 alpha	microtubule binding	Molecular function	-
FABP1	2168	fatty acid binding protein 1, liver	positive regulation of hydrolase activity	Biological process	-
SLC1A1	6505	solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1	membrane	Cellular component	7521911
SGPL1	8879	sphingosine-1-phosphate lyase 1	protein binding	Molecular function	21903422
SRPK2	6733	SRSF protein kinase 2	cytoplasm	Cellular component	-
SRSF9	8683	serine/arginine-rich splicing factor 9	nucleoplasm	Cellular component	-
S100B	6285	S100 calcium binding protein B	response to glucocorticoid	Biological process	-
REEP1	65055	receptor accessory protein 1	microtubule binding	Molecular function	20200447
RBMY1J	378951	RNA binding motif protein, Y-linked, family 1, member J	mRNA processing	Biological process	-
GPR148	344561	G protein-coupled receptor 148	integral component of membrane	Cellular component	-
CRIP1	1396	cysteine-rich protein 1 (intestinal)	cellular response to UV-B	Biological process	20415737
KIF3A	11127	kinesin family member 3A	centrosome	Cellular component	16298999
ADAD1	132612	adenosine deaminase domain containing 1 (testis-specific)	multicellular organismal development	Biological process	-
RBM39	9584	RNA binding motif protein 39	transcription, DNA-templated	Biological process	-
OR2A42	402317	olfactory receptor, family 2, subfamily A, member 42	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
UIMC1	51720	ubiquitin interaction motif containing 1	histone H2A K63-linked deubiquitination	Biological process	19202061
MED6	10001	mediator complex subunit 6	mediator complex	Cellular component	17641689
APOL3	80833	apolipoprotein L, 3	positive regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	12761501
GRIK2	2898	glutamate receptor, ionotropic, kainate 2	glutamate receptor signaling pathway	Biological process	7536611
NAA35	60560	N(alpha)-acetyltransferase 35, NatC auxiliary subunit	smooth muscle cell proliferation	Biological process	-
PTK2	5747	protein tyrosine kinase 2	cytoskeleton	Cellular component	10801330
CDHR5	53841	cadherin-related family member 5	cell adhesion	Biological process	-
CREB1	1385	cAMP responsive element binding protein 1	positive regulation of hormone secretion	Biological process	-
F11R	50848	F11 receptor	slit diaphragm	Cellular component	-
CACNA1C	775	calcium channel, voltage-dependent, L type, alpha 1C subunit	alpha-actinin binding	Molecular function	17110593
DCTN6	10671	dynactin 6	cytosol	Cellular component	-
ESRRB	2103	estrogen-related receptor beta	steroid hormone mediated signaling pathway	Biological process	-
FLT3LG	2323	fms-related tyrosine kinase 3 ligand	cytokine activity	Molecular function	-
LPPR4	9890	lipid phosphate phosphatase-related protein type 4	integral component of plasma membrane	Cellular component	-
ACLY	47	ATP citrate lyase	ATP citrate synthase activity	Molecular function	23932781
TSPY8	728403	testis specific protein, Y-linked 8	cell differentiation	Biological process	-
KANK1	23189	KN motif and ankyrin repeat domains 1	regulation of transcription, DNA-templated	Biological process	-
LPIN2	9663	lipin 2	triglyceride biosynthetic process	Biological process	-
KNSTRN	90417	kinetochore-localized astrin/SPAG5 binding protein	regulation of attachment of spindle microtubules to kinetochore	Biological process	21402792
KCNAB1	7881	potassium channel, voltage gated subfamily A regulatory beta subunit 1	regulation of potassium ion transmembrane transport	Biological process	7890032
ERG	2078	v-ets avian erythroblastosis virus E26 oncogene homolog	signal transduction	Biological process	8502479
BCL2L13	23786	BCL2-like 13 (apoptosis facilitator)	mitochondrial membrane	Cellular component	-
CTNS	1497	cystinosin, lysosomal cystine transporter	lens development in camera-type eye	Biological process	-
RPL17	6139	ribosomal protein L17	cytosolic large ribosomal subunit	Cellular component	12962325
PRKCG	5582	protein kinase C, gamma	negative regulation of protein catabolic process	Biological process	15808853
TAF7L	54457	TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa	transcription regulatory region DNA binding	Molecular function	-
S100A12	6283	S100 calcium binding protein A12	RAGE receptor binding	Molecular function	18443896
PSPH	5723	phosphoserine phosphatase	small molecule metabolic process	Biological process	-
DAZ3	57054	deleted in azoospermia 3	multicellular organismal development	Biological process	-
ITGA8	8516	integrin, alpha 8	metanephros development	Biological process	-
HLX	3142	H2.0-like homeobox	liver development	Biological process	-
TSC2	7249	tuberous sclerosis 2	neural tube closure	Biological process	-
ERN1	2081	endoplasmic reticulum to nucleus signaling 1	peptidyl-serine autophosphorylation	Biological process	20103773
PALB2	79728	partner and localizer of BRCA2	somitogenesis	Biological process	-
UCN2	90226	urocortin 2	hormone activity	Molecular function	-
ANKZF1	55139	ankyrin repeat and zinc finger domain containing 1	membrane	Cellular component	19946888
ADRA2C	152	adrenoceptor alpha 2C	epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway	Biological process	17215105
HOOK3	84376	hook microtubule-tethering protein 3	neuronal stem cell maintenance	Biological process	-
HSPD1	3329	heat shock 60kDa protein 1 (chaperonin)	MyD88-dependent toll-like receptor signaling pathway	Biological process	16148103
PRSS3	5646	protease, serine, 3	serine-type endopeptidase activity	Molecular function	14507909
CD63	967	CD63 molecule	platelet dense granule membrane	Cellular component	-
PSD3	23362	pleckstrin and Sec7 domain containing 3	postsynaptic membrane	Cellular component	-
CCKBR	887	cholecystokinin B receptor	digestion	Biological process	7681836
OMD	4958	osteomodulin	keratan sulfate catabolic process	Biological process	-
GNAT1	2779	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1	GTPase activity	Molecular function	-
ADIPOQ	9370	adiponectin, C1Q and collagen domain containing	positive regulation of signal transduction	Biological process	12368907
IFT57	55081	intraflagellar transport 57	dendrite terminus	Cellular component	-
PPP2R1A	5518	protein phosphatase 2, regulatory subunit A, alpha	mitochondrion	Cellular component	11007961
HDAC2	3066	histone deacetylase 2	histone H3-K9 modification	Biological process	-
IKZF4	64375	IKAROS family zinc finger 4 (Eos)	protein heterodimerization activity	Molecular function	-
TRIP13	9319	thyroid hormone receptor interactor 13	synaptonemal complex assembly	Biological process	-
CD79A	973	CD79a molecule, immunoglobulin-associated alpha	B cell activation	Biological process	-
EPM2AIP1	9852	EPM2A (laforin) interacting protein 1	response to insulin	Biological process	-
CDK5R1	8851	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	superior olivary nucleus maturation	Biological process	-
DCX	1641	doublecortin	intracellular signal transduction	Biological process	-
FOXA2	3170	forkhead box A2	regulation of blood coagulation	Biological process	12911579
MAP2K6	5608	mitogen-activated protein kinase kinase 6	ovulation cycle process	Biological process	-
GPIHBP1	338328	glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1	intracellular protein transport	Biological process	20620994
EPHA7	2045	EPH receptor A7	postsynaptic membrane	Cellular component	-
PALM3	342979	paralemmin 3	response to lipopolysaccharide	Biological process	21187075
VN1R1	57191	vomeronasal 1 receptor 1	G-protein coupled receptor signaling pathway	Biological process	-
FARP1	10160	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)	dendrite morphogenesis	Biological process	-
BGLAP	632	bone gamma-carboxyglutamate (gla) protein	calcium ion binding	Molecular function	-
CCDC64B	146439	coiled-coil domain containing 64B	protein binding	Molecular function	25416956
PPARGC1A	10891	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	DNA binding	Molecular function	10713165
VEGFA	7422	vascular endothelial growth factor A	positive regulation of vascular endothelial growth factor receptor signaling pathway	Biological process	1312256
SOS2	6655	son of sevenless homolog 2 (Drosophila)	regulation of small GTPase mediated signal transduction	Biological process	-
ITGB1	3688	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	cell fate specification	Biological process	-
NOS1AP	9722	nitric oxide synthase 1 (neuronal) adaptor protein	regulation of heart rate by chemical signal	Biological process	19247217
HK3	3101	hexokinase 3 (white cell)	hormone binding	Molecular function	-
SELE	6401	selectin E	leukocyte migration	Biological process	-
TSC2	7249	tuberous sclerosis 2	negative regulation of cell size	Biological process	-
DNAJC6	9829	DnaJ (Hsp40) homolog, subfamily C, member 6	SH3 domain binding	Molecular function	-
NDFIP1	80762	Nedd4 family interacting protein 1	negative regulation of type 2 immune response	Biological process	-
AOC3	8639	amine oxidase, copper containing 3	endoplasmic reticulum	Cellular component	23474851
ATP6V0E1	8992	ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1	phagosome maturation	Biological process	-
HACD3	51495	3-hydroxyacyl-CoA dehydratase 3	endoplasmic reticulum	Cellular component	18554506
TNFRSF10A	8797	tumor necrosis factor receptor superfamily, member 10a	integral component of membrane	Cellular component	9311998
MLLT11	10962	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11	positive regulation of transcription, DNA-templated	Biological process	18852119
SNAP29	9342	synaptosomal-associated protein, 29kDa	vesicle targeting	Biological process	9852078
BMF	90427	Bcl2 modifying factor	programmed cell death	Biological process	-
MEN1	4221	multiple endocrine neoplasia I	MAPK cascade	Biological process	12226747
PRKCH	5583	protein kinase C, eta	blood coagulation	Biological process	-
ACTN4	81	actinin, alpha 4	platelet activation	Biological process	-
PKD2L2	27039	polycystic kidney disease 2-like 2	biological_process	Biological process	-
UGT2A1	10941	UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus	glucuronosyltransferase activity	Molecular function	-
C1QTNF1	114897	C1q and tumor necrosis factor related protein 1	collagen trimer	Cellular component	-
FGD3	89846	FYVE, RhoGEF and PH domain containing 3	regulation of small GTPase mediated signal transduction	Biological process	-
AHNAK	79026	AHNAK nucleoprotein	vesicle	Cellular component	21940993
GNAL	2774	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type	activation of adenylate cyclase activity	Biological process	-
PARP4	143	poly (ADP-ribose) polymerase family, member 4	cell death	Biological process	12140175
DDR1	780	discoidin domain receptor tyrosine kinase 1	integral component of plasma membrane	Cellular component	-
BHLHA9	727857	basic helix-loop-helix family, member a9	DNA binding	Molecular function	-
BAX	581	BCL2-associated X protein	development of secondary sexual characteristics	Biological process	-
SERTAD3	29946	SERTA domain containing 3	transcription, DNA-templated	Biological process	-
VRK2	7444	vaccinia related kinase 2	integral component of membrane	Cellular component	-
ITPR3	3710	inositol 1,4,5-trisphosphate receptor, type 3	fibroblast growth factor receptor signaling pathway	Biological process	-
TOB1	10140	transducer of ERBB2, 1	SMAD binding	Molecular function	-
CERS3	204219	ceramide synthase 3	DNA binding	Molecular function	-
PDGFRL	5157	platelet-derived growth factor receptor-like	extracellular region	Cellular component	-
ATP1B3	483	ATPase, Na+/K+ transporting, beta 3 polypeptide	plasma membrane	Cellular component	-
ASB1	51665	ankyrin repeat and SOCS box containing 1	male genitalia development	Biological process	-
BIRC5	332	baculoviral IAP repeat containing 5	spindle	Cellular component	-
THBS4	7060	thrombospondin 4	response to unfolded protein	Biological process	-
IMPAD1	54928	inositol monophosphatase domain containing 1	metal ion binding	Molecular function	-
HK3	3101	hexokinase 3 (white cell)	cytosol	Cellular component	-
IFNB1	3456	interferon, beta 1, fibroblast	cellular response to exogenous dsRNA	Biological process	21266579
TRAF2	7186	TNF receptor-associated factor 2	signal transduction	Biological process	8702708
BARD1	580	BRCA1 associated RING domain 1	nucleoplasm	Cellular component	-
ACSS1	84532	acyl-CoA synthetase short-chain family member 1	acetate-CoA ligase activity	Molecular function	16788062
IRAK1	3654	interleukin-1 receptor-associated kinase 1	MyD88-independent toll-like receptor signaling pathway	Biological process	-
CYP2R1	120227	cytochrome P450, family 2, subfamily R, polypeptide 1	small molecule metabolic process	Biological process	-
PIK3CA	5290	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	epidermal growth factor receptor signaling pathway	Biological process	-
ZNF284	342909	zinc finger protein 284	metal ion binding	Molecular function	-
EPHB4	2050	EPH receptor B4	heart morphogenesis	Biological process	-
CCL5	6352	chemokine (C-C motif) ligand 5	positive regulation of activation of JAK2 kinase activity	Biological process	11278738
SCAF4	57466	SR-related CTD-associated factor 4	poly(A) RNA binding	Molecular function	22681889
ZNF451	26036	zinc finger protein 451	nucleus	Cellular component	-
ATG14	22863	autophagy related 14	pre-autophagosomal structure membrane	Cellular component	19270696
SULF1	23213	sulfatase 1	N-acetylglucosamine-6-sulfatase activity	Molecular function	19520866
RAB17	64284	RAB17, member RAS oncogene family	GTP binding	Molecular function	-
AGR2	10551	anterior gradient 2	positive regulation of cell-substrate adhesion	Biological process	23274113
NME5	8382	NME/NM23 family member 5	sperm flagellum	Cellular component	-
ACKR2	1238	atypical chemokine receptor 2	chemotaxis	Biological process	-
GEMIN5	25929	gem (nuclear organelle) associated protein 5	protein complex assembly	Biological process	11714716
MAGEA3	4102	melanoma antigen family A3	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	12097332
DCTN3	11258	dynactin 3 (p22)	cytosol	Cellular component	-
LYZ	4069	lysozyme	retina homeostasis	Biological process	23580065
IFNAR1	3454	interferon (alpha, beta and omega) receptor 1	positive regulation of interleukin-1 beta secretion	Biological process	-
PFDN5	5204	prefoldin subunit 5	unfolded protein binding	Molecular function	-
NETO1	81832	neuropilin (NRP) and tolloid (TLL)-like 1	postsynaptic membrane	Cellular component	-
GLI1	2735	GLI family zinc finger 1	notochord regression	Biological process	-
SNTB2	6645	syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)	dystrophin-associated glycoprotein complex	Cellular component	8576247
BMP6	654	bone morphogenetic protein 6	positive regulation of endothelial cell differentiation	Biological process	-
HSD11B1	3290	hydroxysteroid (11-beta) dehydrogenase 1	membrane	Cellular component	19946888
BATF3	55509	basic leucine zipper transcription factor, ATF-like 3	sequence-specific DNA binding transcription factor activity	Molecular function	10878360
CPOX	1371	coproporphyrinogen oxidase	cytoplasm	Cellular component	-
ACTN1	87	actinin, alpha 1	regulation of nucleic acid-templated transcription	Biological process	22351778
SERPINF2	5345	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2	endopeptidase inhibitor activity	Molecular function	2830248
DNAJC10	54431	DnaJ (Hsp40) homolog, subfamily C, member 10	ER-associated ubiquitin-dependent protein catabolic process	Biological process	18400946
MRPL22	29093	mitochondrial ribosomal protein L22	structural constituent of ribosome	Molecular function	-
ZNF22	7570	zinc finger protein 22	DNA binding	Molecular function	-
NRG1	3084	neuregulin 1	transmembrane receptor protein tyrosine kinase signaling pathway	Biological process	7514177
U2AF1	7307	U2 small nuclear RNA auxiliary factor 1	spliceosomal complex	Cellular component	9731529
ITCH	83737	itchy E3 ubiquitin protein ligase	cytoplasm	Cellular component	-
GPER1	2852	G protein-coupled estrogen receptor 1	presynaptic membrane	Cellular component	-
RHOH	399	ras homolog family member H	negative regulation of GTPase activity	Biological process	11809807
FGD2	221472	FYVE, RhoGEF and PH domain containing 2	small GTPase mediated signal transduction	Biological process	-
AICDA	57379	activation-induced cytidine deaminase	negative regulation of methylation-dependent chromatin silencing	Biological process	21496894
UNC13A	23025	unc-13 homolog A (C. elegans)	metal ion binding	Molecular function	-
THEMIS	387357	thymocyte selection associated	COP9 signalosome	Cellular component	-
SRP72	6731	signal recognition particle 72kDa	endoplasmic reticulum	Cellular component	22541560
ANK2	287	ankyrin 2, neuronal	protein targeting to plasma membrane	Biological process	-
SDK2	54549	sidekick cell adhesion molecule 2	integral component of membrane	Cellular component	-
UTP20	27340	UTP20, small subunit (SSU) processome component, homolog (yeast)	poly(A) RNA binding	Molecular function	22658674
CHD3	1107	chromodomain helicase DNA binding protein 3	ATP binding	Molecular function	-
CACNA2D2	9254	calcium channel, voltage-dependent, alpha 2/delta subunit 2	rhythmic synaptic transmission	Biological process	-
SLC30A3	7781	solute carrier family 30 (zinc transporter), member 3	integral component of plasma membrane	Cellular component	8962159
FOXM1	2305	forkhead box M1	liver development	Biological process	-
FECH	2235	ferrochelatase	regulation of hemoglobin biosynthetic process	Biological process	-
MEF2C	4208	myocyte enhancer factor 2C	germinal center formation	Biological process	-
ZBTB21	49854	zinc finger and BTB domain containing 21	protein binding	Molecular function	15629158
PIK3CA	5290	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	cell chemotaxis	Biological process	-
ZNF766	90321	zinc finger protein 766	nucleus	Cellular component	21630459
ISOC1	51015	isochorismatase domain containing 1	catalytic activity	Molecular function	-
PKIA	5569	protein kinase (cAMP-dependent, catalytic) inhibitor alpha	negative regulation of protein import into nucleus	Biological process	-
RPS27L	51065	ribosomal protein S27-like	activation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	17057733
FGF10	2255	fibroblast growth factor 10	type 2 fibroblast growth factor receptor binding	Molecular function	19224135
GNB5	10681	guanine nucleotide binding protein (G protein), beta 5	signal transduction	Biological process	9606987
IKBKB	3551	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	ATP binding	Molecular function	-
TGM2	7052	transglutaminase 2	negative regulation of endoplasmic reticulum calcium ion concentration	Biological process	24349085
TAL2	6887	T-cell acute lymphocytic leukemia 2	RNA polymerase II regulatory region sequence-specific DNA binding	Molecular function	-
KLF4	9314	Kruppel-like factor 4 (gut)	negative regulation of muscle hyperplasia	Biological process	-
PIKFYVE	200576	phosphoinositide kinase, FYVE finger containing	metal ion binding	Molecular function	-
PDXK	8566	pyridoxal (pyridoxine, vitamin B6) kinase	nucleus	Cellular component	21630459
SRP14	6727	signal recognition particle 14kDa (homologous Alu RNA binding protein)	protein binding	Molecular function	22720776
ABL2	27	ABL proto-oncogene 2, non-receptor tyrosine kinase	regulation of cell motility	Biological process	20841568
KIF15	56992	kinesin family member 15	microtubule motor activity	Molecular function	-
ANXA1	301	annexin A1	peptide cross-linking	Biological process	10908733
CNOT1	23019	CCR4-NOT transcription complex, subunit 1	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	Biological process	-
SERPINA3	12	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3	maintenance of gastrointestinal epithelium	Biological process	8647626
CPE	1363	carboxypeptidase E	plasma membrane	Cellular component	9019408
RPA2	6118	replication protein A2, 32kDa	translesion synthesis	Biological process	-
RET	5979	ret proto-oncogene	retina development in camera-type eye	Biological process	-
FASN	2194	fatty acid synthase	palmitoyl-[acyl-carrier-protein] hydrolase activity	Molecular function	-
HNF4A	3172	hepatocyte nuclear factor 4, alpha	steroid hormone receptor activity	Molecular function	-
VAX2	25806	ventral anterior homeobox 2	Wnt signaling pathway	Biological process	-
EHMT1	79813	euchromatic histone-lysine N-methyltransferase 1	negative regulation of transcription, DNA-templated	Biological process	-
EDEM2	55741	ER degradation enhancer, mannosidase alpha-like 2	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	Molecular function	15537790
DLGAP2	9228	discs, large (Drosophila) homolog-associated protein 2	cell junction	Cellular component	-
GRIA1	2890	glutamate receptor, ionotropic, AMPA 1	ion transmembrane transport	Biological process	-
STX6	10228	syntaxin 6	integral component of membrane	Cellular component	-
AGO2	27161	argonaute RISC catalytic component 2	epidermal growth factor receptor signaling pathway	Biological process	-
PRKAR1B	5575	protein kinase, cAMP-dependent, regulatory, type I, beta	cAMP-dependent protein kinase regulator activity	Molecular function	1708242
PGAP3	93210	post-GPI attachment to proteins 3	Golgi membrane	Cellular component	-
ACOT1	641371	acyl-CoA thioesterase 1	palmitoyl-CoA hydrolase activity	Molecular function	-
POLR3G	10622	polymerase (RNA) III (DNA directed) polypeptide G (32kD)	DNA-directed RNA polymerase activity	Molecular function	9171375
ALOXE3	59344	arachidonate lipoxygenase 3	fat cell differentiation	Biological process	-
CTSL3P	392360	cathepsin L family member 3, pseudogene	proteolysis	Biological process	-
ZNF131	7690	zinc finger protein 131	sequence-specific DNA binding transcription factor activity	Molecular function	7557990
MAZ	4150	MYC-associated zinc finger protein (purine-binding transcription factor)	termination of RNA polymerase II transcription	Biological process	1502157
NCKAP1	10787	NCK-associated protein 1	protein complex binding	Molecular function	18560548
ZDHHC23	254887	zinc finger, DHHC-type containing 23	integral component of membrane	Cellular component	-
PRKACA	5566	protein kinase, cAMP-dependent, catalytic, alpha	nucleus	Cellular component	21630459
TGFB1	7040	transforming growth factor, beta 1	protein import into nucleus, translocation	Biological process	21390327
TRAF3	7187	TNF receptor-associated factor 3	cytoplasmic side of plasma membrane	Cellular component	-
MAN2B2	23324	mannosidase, alpha, class 2B, member 2	alpha-mannosidase activity	Molecular function	-
MFSD10	10227	major facilitator superfamily domain containing 10	integral component of membrane	Cellular component	-
RECQL5	9400	RecQ protein-like 5	chromosome separation	Biological process	22013166
RPS6KB1	6198	ribosomal protein S6 kinase, 70kDa, polypeptide 1	response to electrical stimulus involved in regulation of muscle adaptation	Biological process	-
KLHL3	26249	kelch-like family member 3	cytoskeleton	Cellular component	-
TNR	7143	tenascin R	cell adhesion	Biological process	8940128
VPS11	55823	vacuolar protein sorting 11 homolog (S. cerevisiae)	positive regulation of protein targeting to mitochondrion	Biological process	24270810
GALNS	2588	galactosamine (N-acetyl)-6-sulfatase	keratan sulfate catabolic process	Biological process	-
PLAGL1	5325	pleiomorphic adenoma gene-like 1	apoptotic process	Biological process	9671765
CNGA3	1261	cyclic nucleotide gated channel alpha 3	integral component of plasma membrane	Cellular component	-
HIF1AN	55662	hypoxia inducible factor 1, alpha subunit inhibitor	positive regulation of myoblast differentiation	Biological process	18299578
PKD1L2	114780	polycystic kidney disease 1-like 2 (gene/pseudogene)	membrane	Cellular component	-
ATP7A	538	ATPase, Cu++ transporting, alpha polypeptide	neuron projection	Cellular component	-
SOX8	30812	SRY (sex determining region Y)-box 8	fat cell differentiation	Biological process	-
HMGB1	3146	high mobility group box 1	double-stranded DNA binding	Molecular function	-
GATA1	2623	GATA binding protein 1 (globin transcription factor 1)	in utero embryonic development	Biological process	-
AZGP1	563	alpha-2-glycoprotein 1, zinc-binding	extracellular space	Cellular component	16502470
H2BFS	54145	H2B histone family, member S (pseudogene)	defense response to Gram-positive bacterium	Biological process	12860195
EGFR	1956	epidermal growth factor receptor	response to oxidative stress	Biological process	-
CRYBB3	1417	crystallin, beta B3	protein binding	Molecular function	25416956
TBX21	30009	T-box 21	positive regulation of isotype switching to IgG isotypes	Biological process	-
SNW1	22938	SNW domain containing 1	transforming growth factor beta receptor signaling pathway	Biological process	-
HIST1H3E	8353	histone cluster 1, H3e	protein heterodimerization activity	Molecular function	-
C1orf186	440712	chromosome 1 open reading frame 186	integral component of membrane	Cellular component	-
MOXD2P	100289017	monooxygenase, DBH-like 2, pseudogene	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen	Molecular function	-
AMICA1	120425	adhesion molecule, interacts with CXADR antigen 1	monocyte extravasation	Biological process	18948633
UNC5C	8633	unc-5 homolog C (C. elegans)	positive regulation of apoptotic process	Biological process	-
EPOR	2057	erythropoietin receptor	brain development	Biological process	-
CDKN1A	1026	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	negative regulation of cell growth	Biological process	10208428
ADAM5	255926	ADAM metallopeptidase domain 5 (pseudogene)	zinc ion binding	Molecular function	-
VAMP4	8674	vesicle-associated membrane protein 4	lysosome	Cellular component	9553086
PSEN2	5664	presenilin 2	perinuclear region of cytoplasm	Cellular component	-
CNTF	1270	ciliary neurotrophic factor	positive regulation of cell proliferation	Biological process	-
FYN	2534	FYN proto-oncogene, Src family tyrosine kinase	calcium ion transport	Biological process	7822789
DAP	1611	death-associated protein	apoptotic signaling pathway	Biological process	1087798
KDSR	2531	3-ketodihydrosphingosine reductase	sphingolipid biosynthetic process	Biological process	-
PXYLP1	92370	2-phosphoxylose phosphatase 1	dephosphorylation	Biological process	-
OASL	8638	2'-5'-oligoadenylate synthetase-like	negative regulation of viral genome replication	Biological process	18931074
TRAF6	7189	TNF receptor-associated factor 6, E3 ubiquitin protein ligase	odontogenesis of dentin-containing tooth	Biological process	-
SMURF1	57154	SMAD specific E3 ubiquitin protein ligase 1	neuronal cell body	Cellular component	-
CRH	1392	corticotropin releasing hormone	response to drug	Biological process	-
BRAF	673	B-Raf proto-oncogene, serine/threonine kinase	regulation of cell proliferation	Biological process	-
MYL3	4634	myosin, light chain 3, alkali; ventricular, skeletal, slow	sarcomere	Cellular component	16754800
CITED2	10370	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	cell differentiation	Biological process	-
ATXN3	4287	ataxin 3	nucleoplasm	Cellular component	9580663
IL3	3562	interleukin 3	nervous system development	Biological process	9736740
KDM4A	9682	lysine (K)-specific demethylase 4A	transcription, DNA-templated	Biological process	-
DICER1	23405	dicer 1, ribonuclease type III	apoptotic DNA fragmentation	Biological process	-
TLR2	7097	toll-like receptor 2	diacyl lipopeptide binding	Molecular function	-
SSPN	8082	sarcospan	integral component of plasma membrane	Cellular component	-
CDKN1A	1026	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	cyclin-dependent protein kinase holoenzyme complex	Cellular component	17420273
CDH4	1002	cadherin 4, type 1, R-cadherin (retinal)	homophilic cell adhesion via plasma membrane adhesion molecules	Biological process	-
RHPN1	114822	rhophilin, Rho GTPase binding protein 1	protein binding	Molecular function	25416956
PCDHA1	56147	protocadherin alpha 1	homophilic cell adhesion via plasma membrane adhesion molecules	Biological process	-
SLC25A13	10165	solute carrier family 25 (aspartate/glutamate carrier), member 13	transport	Biological process	10642534
NRXN3	9369	neurexin 3	cell adhesion molecule binding	Molecular function	18923512
ARRB2	409	arrestin, beta 2	14-3-3 protein binding	Molecular function	-
AARS2	57505	alanyl-tRNA synthetase 2, mitochondrial	ATP binding	Molecular function	-
ITGB3	3690	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	smooth muscle cell migration	Biological process	8837777
TIMM23	100287932	translocase of inner mitochondrial membrane 23 homolog (yeast)	protein targeting to mitochondrion	Biological process	-
FMR1	2332	fragile X mental retardation 1	membrane	Cellular component	19946888
TAS2R4	50832	taste receptor, type 2, member 4	plasma membrane	Cellular component	-
FHL3	2275	four and a half LIM domains 3	focal adhesion	Cellular component	21423176
ZNF45	7596	zinc finger protein 45	multicellular organismal development	Biological process	1559709
DRG1	4733	developmentally regulated GTP binding protein 1	membrane	Cellular component	19946888
BCAP31	10134	B-cell receptor-associated protein 31	integral component of plasma membrane	Cellular component	8706661
GNPTAB	79158	N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits	lysosome organization	Biological process	21719679
MCUR1	63933	mitochondrial calcium uniporter regulator 1	protein binding	Molecular function	23178883
CNEP1R1	255919	CTD nuclear envelope phosphatase 1 regulatory subunit 1	mitotic cell cycle	Biological process	-
KIT	3815	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	positive regulation of tyrosine phosphorylation of Stat5 protein	Biological process	21135090
DOK7	285489	docking protein 7	insulin receptor binding	Molecular function	-
CEP164	22897	centrosomal protein 164kDa	cell division	Biological process	-
IL13RA1	3597	interleukin 13 receptor, alpha 1	protein binding	Molecular function	12935900
SEC13	6396	SEC13 homolog (S. cerevisiae)	small GTPase mediated signal transduction	Biological process	-
FOXC1	2296	forkhead box C1	in utero embryonic development	Biological process	-
PIK3C3	5289	phosphatidylinositol 3-kinase, catalytic subunit type 3	endosome organization	Biological process	-
Sep-04	5414	septin 4	protein binding	Molecular function	17685441
VAMP8	8673	vesicle-associated membrane protein 8	neutrophil degranulation	Biological process	16677249
DARS	1615	aspartyl-tRNA synthetase	extracellular exosome	Cellular component	20458337
LIMS1	3987	LIM and senescent cell antigen-like domains 1	establishment of protein localization	Biological process	20926685
MAGI2	9863	membrane associated guanylate kinase, WW and PDZ domain containing 2	negative regulation of cell proliferation	Biological process	-
ESX1	80712	ESX homeobox 1	sequence-specific DNA binding	Molecular function	15897875
RALGPS2	55103	Ral GEF with PH domain and SH3 binding motif 2	small GTPase mediated signal transduction	Biological process	-
EAF1	85403	ELL associated factor 1	regulation of transcription, DNA-templated	Biological process	-
EXOSC10	5394	exosome component 10	nuclear-transcribed mRNA catabolic process	Biological process	17545563
VCP	7415	valosin containing protein	site of double-strand break	Cellular component	22120668
NPHP1	4867	nephronophthisis 1 (juvenile)	retina development in camera-type eye	Biological process	-
KPNA4	3840	karyopherin alpha 4 (importin alpha 3)	nucleoplasm	Cellular component	-
UPK3A	7380	uroplakin 3A	urea transport	Biological process	-
NFXL1	152518	nuclear transcription factor, X-box binding-like 1	RNA polymerase II regulatory region sequence-specific DNA binding	Molecular function	-
UHMK1	127933	U2AF homology motif (UHM) kinase 1	cell cycle arrest	Biological process	12093740
CYP27B1	1594	cytochrome P450, family 27, subfamily B, polypeptide 1	regulation of bone mineralization	Biological process	9415400
PSMC4	5704	proteasome (prosome, macropain) 26S subunit, ATPase, 4	viral process	Biological process	-
HPS1	3257	Hermansky-Pudlak syndrome 1	positive regulation of natural killer cell activation	Biological process	-
SFTPC	6440	surfactant protein C	protein homodimerization activity	Molecular function	-
PIK3R2	5296	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	insulin receptor signaling pathway	Biological process	-
CSF1R	1436	colony stimulating factor 1 receptor	hemopoiesis	Biological process	7683918
GPR37L1	9283	G protein-coupled receptor 37 like 1	receptor complex	Cellular component	23382219
DST	667	dystonin	hemidesmosome	Cellular component	11375975
AXIN1	8312	axin 1	postsynaptic density	Cellular component	-
CARHSP1	23589	calcium regulated heat stable protein 1, 24kDa	cytosol	Cellular component	-
CNR1	1268	cannabinoid receptor 1 (brain)	negative regulation of action potential	Biological process	-
HDAC2	3066	histone deacetylase 2	negative regulation of apoptotic process	Biological process	21093383
SRD5A3	79644	steroid 5 alpha-reductase 3	post-translational protein modification	Biological process	-
HSPA5	3309	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	focal adhesion	Cellular component	21423176
DUSP14	11072	dual specificity phosphatase 14	peptidyl-tyrosine dephosphorylation	Biological process	-
DSC3	1825	desmocollin 3	calcium ion binding	Molecular function	-
SAP30BP	29115	SAP30 binding protein	nucleus	Cellular component	9651585
NEDD4	4734	neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase	T cell activation	Biological process	-
MIDN	90007	midnolin	negative regulation of glucokinase activity	Biological process	-
ADA	100	adenosine deaminase	positive regulation of B cell proliferation	Biological process	-
SYN1	6853	synapsin I	calcium-dependent protein binding	Molecular function	-
C1orf86	199990	chromosome 1 open reading frame 86	ubiquitin binding	Molecular function	22266823
ITGAV	3685	integrin, alpha V	filopodium membrane	Cellular component	25063885
RYR2	6262	ryanodine receptor 2 (cardiac)	response to hypoxia	Biological process	-
SURF1	6834	surfeit 1	mitochondrial respiratory chain	Cellular component	9843204
SDC4	6385	syndecan 4	retinoid metabolic process	Biological process	-
PHF7	51533	PHD finger protein 7	microtubule organizing center	Cellular component	-
FOXRED2	80020	FAD-dependent oxidoreductase domain containing 2	oxidation-reduction process	Biological process	-
PDE2A	5138	phosphodiesterase 2A, cGMP-stimulated	metal ion binding	Molecular function	-
SORBS1	10580	sorbin and SH3 domain containing 1	centrosome	Cellular component	-
APOB	338	apolipoprotein B	response to carbohydrate	Biological process	-
M1AP	130951	meiosis 1 associated protein	female gamete generation	Biological process	16881047
FOLR2	2350	folate receptor 2 (fetal)	folic acid binding	Molecular function	4066659
TAS2R60	338398	taste receptor, type 2, member 60	bitter taste receptor activity	Molecular function	20022913
ARHGAP28	79822	Rho GTPase activating protein 28	cytosol	Cellular component	-
BPGM	669	2,3-bisphosphoglycerate mutase	bisphosphoglycerate mutase activity	Molecular function	-
OR2Z1	284383	olfactory receptor, family 2, subfamily Z, member 1	integral component of membrane	Cellular component	-
PNPLA6	10908	patatin-like phospholipase domain containing 6	angiogenesis	Biological process	-
TRIM36	55521	tripartite motif containing 36	zinc ion binding	Molecular function	-
RYR2	6262	ryanodine receptor 2 (cardiac)	plasma membrane	Cellular component	-
NEK6	10783	NIMA-related kinase 6	nuclear speck	Cellular component	-
TK1	7083	thymidine kinase 1, soluble	skeletal muscle cell proliferation	Biological process	-
DPF3	8110	D4, zinc and double PHD fingers, family 3	chromatin modification	Biological process	-
DDX3X	1654	DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked	cytoplasmic stress granule	Cellular component	18596238
RNF220	55182	ring finger protein 220	cytoplasm	Cellular component	-
MKL1	57591	megakaryoblastic leukemia (translocation) 1	leucine zipper domain binding	Molecular function	14970199
COL3A1	1281	collagen, type III, alpha 1	extracellular space	Cellular component	9036918
EPS8L1	54869	EPS8-like 1	positive regulation of GTPase activity	Biological process	14565974
MAPT	4137	microtubule-associated protein tau	neuron migration	Biological process	-
RPS25	6230	ribosomal protein S25	extracellular exosome	Cellular component	20458337
GABRA5	2558	gamma-aminobutyric acid (GABA) A receptor, alpha 5	receptor complex	Cellular component	-
CDKL4	344387	cyclin-dependent kinase-like 4	protein phosphorylation	Biological process	-
IL1B	3553	interleukin 1, beta	protein kinase B signaling	Biological process	21147091
EPO	2056	erythropoietin	positive regulation of transcription, DNA-templated	Biological process	9722506
GDF6	392255	growth differentiation factor 6	growth factor activity	Molecular function	-
RET	5979	ret proto-oncogene	homophilic cell adhesion via plasma membrane adhesion molecules	Biological process	-
IRF4	3662	interferon regulatory factor 4	cytosol	Cellular component	-
CHCHD6	84303	coiled-coil-helix-coiled-coil-helix domain containing 6	cellular response to DNA damage stimulus	Biological process	22228767
CNOT7	29883	CCR4-NOT transcription complex, subunit 7	exoribonuclease activity	Molecular function	19276069
VAMP3	9341	vesicle-associated membrane protein 3	clathrin-coated vesicle membrane	Cellular component	-
ROPN1B	152015	rhophilin associated tail protein 1B	receptor signaling complex scaffold activity	Molecular function	11278869
SLC35F6	54978	solute carrier family 35, member F6	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	Biological process	19154410
CACNA1A	773	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	sulfur amino acid metabolic process	Biological process	-
IL6ST	3572	interleukin 6 signal transducer	interleukin-11 binding	Molecular function	-
TUBB3	10381	tubulin, beta 3 class III	GTP binding	Molecular function	-
ATP1A1	476	ATPase, Na+/K+ transporting, alpha 1 polypeptide	response to glycoside	Biological process	11546672
NLRP4	147945	NLR family, pyrin domain containing 4	positive regulation of type I interferon production	Biological process	-
GJB3	2707	gap junction protein, beta 3, 31kDa	connexon complex	Cellular component	-
ROBO2	6092	roundabout, axon guidance receptor, homolog 2 (Drosophila)	axon guidance receptor activity	Molecular function	9458045
EMILIN1	11117	elastin microfibril interfacer 1	extracellular exosome	Cellular component	21362503
ZNF705D	728957	zinc finger protein 705D	metal ion binding	Molecular function	-
RELA	5970	v-rel avian reticuloendotheliosis viral oncogene homolog A	acetaldehyde metabolic process	Biological process	-
PARP8	79668	poly (ADP-ribose) polymerase family, member 8	NAD+ ADP-ribosyltransferase activity	Molecular function	-
FAM156A	29057	family with sequence similarity 156, member A	protein binding	Molecular function	25416956
NCF2	4688	neutrophil cytosolic factor 2	nucleolus	Cellular component	-
ERVK-6	64006	endogenous retrovirus group K, member 6	RNA phosphodiester bond hydrolysis, endonucleolytic	Biological process	-
NPM1	4869	nucleophosmin (nucleolar phosphoprotein B23, numatrin)	ribosomal small subunit binding	Molecular function	18809582
KANSL3	55683	KAT8 regulatory NSL complex subunit 3	histone H4-K5 acetylation	Biological process	20018852
ATR	545	ATR serine/threonine kinase	double-strand break repair via homologous recombination	Biological process	-
CYP2C18	1562	cytochrome P450, family 2, subfamily C, polypeptide 18	heme binding	Molecular function	-
HINFP	25988	histone H4 transcription factor	regulation of gene expression	Biological process	15988025
STXBP1	6812	syntaxin binding protein 1	neurotransmitter secretion	Biological process	-
ERAL1	26284	Era-like 12S mitochondrial rRNA chaperone 1	rRNA binding	Molecular function	20604745
WWC1	23286	WW and C2 domain containing 1	negative regulation of hippo signaling	Biological process	24682284
C14orf166	51637	chromosome 14 open reading frame 166	positive regulation of transcription from RNA polymerase II promoter	Biological process	16950395
MAP1B	4131	microtubule-associated protein 1B	dendritic spine	Cellular component	-
GYPC	2995	glycophorin C (Gerbich blood group)	cortical cytoskeleton	Cellular component	16669616
MSGN1	343930	mesogenin 1	DNA binding	Molecular function	-
DLX4	1748	distal-less homeobox 4	regulation of transcription, DNA-templated	Biological process	11069021
PITX3	5309	paired-like homeodomain 3	transcription, DNA-templated	Biological process	-
GBX1	2636	gastrulation brain homeobox 1	nucleus	Cellular component	-
POLR3A	11128	polymerase (RNA) III (DNA directed) polypeptide A, 155kDa	positive regulation of protein targeting to mitochondrion	Biological process	24912190
FOXQ1	94234	forkhead box Q1	hair follicle morphogenesis	Biological process	-
ABCC4	10257	ATP-binding cassette, sub-family C (CFTR/MRP), member 4	basolateral plasma membrane	Cellular component	24130369
SLC29A1	2030	solute carrier family 29 (equilibrative nucleoside transporter), member 1	plasma membrane	Cellular component	-
PDCD10	11235	programmed cell death 10	regulation of Rho protein signal transduction	Biological process	20332113
ALS2	57679	amyotrophic lateral sclerosis 2 (juvenile)	dendrite	Cellular component	15371724
TFAP4	7023	transcription factor AP-4 (activating enhancer binding protein 4)	protein binding	Molecular function	19505873
OR10D3	26497	olfactory receptor, family 10, subfamily D, member 3 (non-functional)	G-protein coupled receptor signaling pathway	Biological process	-
PLAC8	51316	placenta-specific 8	response to cold	Biological process	-
CETN1	1068	centrin, EF-hand protein, 1	calcium ion binding	Molecular function	-
MS4A1	931	membrane-spanning 4-domains, subfamily A, member 1	extracellular exosome	Cellular component	20458337
ADRA1A	148	adrenoceptor alpha 1A	organ growth	Biological process	-
ITGB1	3688	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	blood coagulation	Biological process	-
P3H3	10536	prolyl 3-hydroxylase 3	negative regulation of cell proliferation	Biological process	19436308
PSAP	5660	prosaposin	regulation of MAPK cascade	Biological process	-
S100A12	6283	S100 calcium binding protein A12	innate immune response	Biological process	18443896
GUCY1A3	2982	guanylate cyclase 1, soluble, alpha 3	GTP binding	Molecular function	-
TXLNA	200081	taxilin alpha	protein binding	Molecular function	21903422
ZCRB1	85437	zinc finger CCHC-type and RNA binding motif 1	zinc ion binding	Molecular function	-
MAGOH	4116	mago-nashi homolog, proliferation-associated (Drosophila)	nucleoplasm	Cellular component	-
ADAM8	101	ADAM metallopeptidase domain 8	alpha9-beta1 integrin-ADAM8 complex	Cellular component	-
SHC1	6464	SHC (Src homology 2 domain containing) transforming protein 1	cytosol	Cellular component	-
FOXB2	442425	forkhead box B2	regulation of transcription from RNA polymerase II promoter	Biological process	-
SFXN5	94097	sideroflexin 5	citrate transmembrane transporter activity	Molecular function	-
EIF2B2	8892	eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa	GTP binding	Molecular function	11323413
ANO6	196527	anoctamin 6	bone mineralization involved in bone maturation	Biological process	-
RARS2	57038	arginyl-tRNA synthetase 2, mitochondrial	ATP binding	Molecular function	-
HEY1	23462	hes-related family bHLH transcription factor with YRPW motif 1	Notch signaling pathway	Biological process	-
EBI3	10148	Epstein-Barr virus induced 3	positive regulation of alpha-beta T cell proliferation	Biological process	14743498
FCGR1A	2209	Fc fragment of IgG, high affinity Ia, receptor (CD64)	intracellular signal transduction	Biological process	10879688
KLF2	10365	Kruppel-like factor 2	cellular response to cycloheximide	Biological process	-
HTR2C	3358	5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled	phospholipase C-activating G-protein coupled receptor signaling pathway	Biological process	12970106
ATP1A1	476	ATPase, Na+/K+ transporting, alpha 1 polypeptide	steroid hormone binding	Molecular function	14742675
FNBP1L	54874	formin binding protein 1-like	membrane tubulation	Biological process	20730103
ANAPC2	29882	anaphase promoting complex subunit 2	positive regulation of dendrite morphogenesis	Biological process	-
WFS1	7466	Wolfram syndrome 1 (wolframin)	olfactory behavior	Biological process	-
STK38L	23012	serine/threonine kinase 38 like	protein phosphorylation	Biological process	15037617
KDM2B	84678	lysine (K)-specific demethylase 2B	DNA binding	Molecular function	10799292
MINA	84864	MYC induced nuclear antigen	dioxygenase activity	Molecular function	-
ZDHHC15	158866	zinc finger, DHHC-type containing 15	establishment of protein localization	Biological process	-
PLA2G10	8399	phospholipase A2, group X	negative regulation of cholesterol efflux	Biological process	20844270
ZBED3	84327	zinc finger, BED-type containing 3	positive regulation of canonical Wnt signaling pathway	Biological process	-
TBRG4	9238	transforming growth factor beta regulator 4	protein kinase activity	Molecular function	-
NACA	4666	nascent polypeptide-associated complex alpha subunit	transcription coactivator activity	Molecular function	21071677
H1F0	3005	H1 histone family, member 0	nucleosome	Cellular component	-
ATG9A	79065	autophagy related 9A	mitochondrion degradation	Biological process	-
ITGB4	3691	integrin, beta 4	digestive tract development	Biological process	23496044
CASP9	842	caspase 9, apoptosis-related cysteine peptidase	cysteine-type endopeptidase activity	Molecular function	9390557
GBF1	8729	golgi brefeldin A resistant guanine nucleotide exchange factor 1	Golgi to endosome transport	Biological process	23386609
LOXL3	84695	lysyl oxidase-like 3	epithelial to mesenchymal transition	Biological process	16096638
BMP1	649	bone morphogenetic protein 1	metallopeptidase activity	Molecular function	7798260
METTL23	124512	methyltransferase like 23	cytoplasm	Cellular component	-
RAC3	5881	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	positive regulation of substrate adhesion-dependent cell spreading	Biological process	11756406
ANP32E	81611	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E	negative regulation of catalytic activity	Biological process	-
SP8	221833	Sp8 transcription factor	regulation of transcription, DNA-templated	Biological process	-
MYCBP2	23077	MYC binding protein 2, E3 ubiquitin protein ligase	nucleus	Cellular component	-
CHEK1	1111	checkpoint kinase 1	cellular response to DNA damage stimulus	Biological process	20932473
COLEC10	10584	collectin sub-family member 10 (C-type lectin)	cytoplasm	Cellular component	10224141
UNC13B	10497	unc-13 homolog B (C. elegans)	neurotransmitter secretion	Biological process	-
ANK3	288	ankyrin 3, node of Ranvier (ankyrin G)	costamere	Cellular component	21223964
PLEKHM3	389072	pleckstrin homology domain containing, family M, member 3	metal ion binding	Molecular function	-
RPS6KB1	6198	ribosomal protein S6 kinase, 70kDa, polypeptide 1	peptide binding	Molecular function	-
DUSP19	142679	dual specificity phosphatase 19	mitogen-activated protein kinase kinase kinase binding	Molecular function	-
CHRM3	1131	cholinergic receptor, muscarinic 3	phosphatidylinositol phospholipase C activity	Molecular function	1905013
STAR	6770	steroidogenic acute regulatory protein	testosterone biosynthetic process	Biological process	-
HOXC5	3222	homeobox C5	embryonic skeletal system development	Biological process	-
BPY2B	442867	basic charge, Y-linked, 2B	HECT domain binding	Molecular function	12207887
SIX6	4990	SIX homeobox 6	organ morphogenesis	Biological process	10512683
GRIN1	2902	glutamate receptor, ionotropic, N-methyl D-aspartate 1	cellular response to manganese ion	Biological process	-
NQO1	1728	NAD(P)H dehydrogenase, quinone 1	identical protein binding	Molecular function	25143260
DYNLT3	6990	dynein, light chain, Tctex-type 3	regulation of mitotic cell cycle	Biological process	-
SENP1	29843	SUMO1/sentrin specific peptidase 1	regulation of definitive erythrocyte differentiation	Biological process	-
SAE1	10055	SUMO1 activating enzyme subunit 1	SUMO activating enzyme activity	Molecular function	20164921
HTRA2	27429	HtrA serine peptidase 2	cellular response to interferon-beta	Biological process	17297443
ZBTB4	57659	zinc finger and BTB domain containing 4	negative regulation of transcription from RNA polymerase II promoter	Biological process	16354688
EHD2	30846	EH-domain containing 2	plasma membrane	Cellular component	-
PPP1R2	5504	protein phosphatase 1, regulatory (inhibitor) subunit 2	negative regulation of catalytic activity	Biological process	8119416
RDH13	112724	retinol dehydrogenase 13 (all-trans/9-cis)	response to high light intensity	Biological process	-
LIF	3976	leukemia inhibitory factor	muscle organ morphogenesis	Biological process	-
CALR3	125972	calreticulin 3	endoplasmic reticulum lumen	Cellular component	-
NCALD	83988	neurocalcin delta	cytosol	Cellular component	-
CHD2	1106	chromodomain helicase DNA binding protein 2	poly(A) RNA binding	Molecular function	22658674
PEAR1	375033	platelet endothelial aggregation receptor 1	recognition of apoptotic cell	Biological process	-
PTPRU	10076	protein tyrosine phosphatase, receptor type, U	plasma membrane	Cellular component	-
PAX6	5080	paired box 6	positive regulation of epithelial cell differentiation	Biological process	-
KIAA1549	57670	KIAA1549	integral component of membrane	Cellular component	-
CHRNG	1146	cholinergic receptor, nicotinic, gamma (muscle)	channel activity	Molecular function	3967651
GRB2	2885	growth factor receptor-bound protein 2	aging	Biological process	-
CACUL1	143384	CDK2-associated, cullin domain 1	positive regulation of cell proliferation	Biological process	19829063
ASIC1	41	acid sensing (proton gated) ion channel 1	ion transmembrane transport	Biological process	-
ZC3H7B	23264	zinc finger CCCH-type containing 7B	protein binding	Molecular function	15047801
ITGA1	3672	integrin, alpha 1	positive regulation of neuron apoptotic process	Biological process	-
ADH6	130	alcohol dehydrogenase 6 (class V)	cytosol	Cellular component	-
ARRB2	409	arrestin, beta 2	positive regulation of protein ubiquitination	Biological process	19372219
INSM1	3642	insulinoma-associated 1	noradrenergic neuron development	Biological process	-
REEP3	221035	receptor accessory protein 3	endoplasmic reticulum membrane	Cellular component	-
NEUROG2	63973	neurogenin 2	forebrain development	Biological process	-
CKLF	51192	chemokine-like factor	lymphocyte chemotaxis	Biological process	11415443
CPSF4	10898	cleavage and polyadenylation specific factor 4, 30kDa	mRNA cleavage and polyadenylation specificity factor complex	Cellular component	21102410
SH2B3	10019	SH2B adaptor protein 3	embryonic hemopoiesis	Biological process	-
CEBPA	1050	CCAAT/enhancer binding protein (C/EBP), alpha	granulocyte differentiation	Biological process	-
IFT88	8100	intraflagellar transport 88	anterior/posterior pattern specification	Biological process	-
DIRAS1	148252	DIRAS family, GTP-binding RAS-like 1	small GTPase mediated signal transduction	Biological process	-
PIK3R2	5296	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	receptor tyrosine kinase binding	Molecular function	10627473
PCNT	5116	pericentrin	negative regulation of apoptotic process	Biological process	-
PLCD4	84812	phospholipase C, delta 4	calcium ion binding	Molecular function	-
RAB27B	5874	RAB27B, member RAS oncogene family	myosin V binding	Molecular function	15357836
HP	3240	haptoglobin	acute-phase response	Biological process	-
IL13	3596	interleukin 13	negative regulation of lung ciliated cell differentiation	Biological process	20539013
MPPED1	758	metallophosphoesterase domain containing 1	metabolic process	Biological process	-
CNTNAP2	26047	contactin associated protein-like 2	learning	Biological process	18179893
BCS1L	617	BC1 (ubiquinol-cytochrome c reductase) synthesis-like	mitochondrial respiratory chain complex III	Cellular component	9878253
ARHGAP4	393	Rho GTPase activating protein 4	negative regulation of cell migration	Biological process	-
PDXP	57026	pyridoxal (pyridoxine, vitamin B6) phosphatase	regulation of cytokinesis	Biological process	15580268
MYPOP	339344	Myb-related transcription factor, partner of profilin	chromatin binding	Molecular function	-
MSL1	339287	male-specific lethal 1 homolog (Drosophila)	MSL complex	Cellular component	20018852
PAPPA2	60676	pappalysin 2	regulation of cell growth	Biological process	11264294
LPPR1	54886	lipid phosphate phosphatase-related protein type 1	metabolic process	Biological process	-
DTL	51514	denticleless E3 ubiquitin protein ligase homolog (Drosophila)	regulation of cell cycle	Biological process	17085480
AQP1	358	aquaporin 1 (Colton blood group)	sensory perception of pain	Biological process	-
SIN3A	25942	SIN3 transcription regulator family member A	RNA polymerase II repressing transcription factor binding	Molecular function	-
HLA-B	3106	major histocompatibility complex, class I, B	regulation of immune response	Biological process	-
ADAR	103	adenosine deaminase, RNA-specific	hematopoietic progenitor cell differentiation	Biological process	-
CHRM3	1131	cholinergic receptor, muscarinic 3	nervous system development	Biological process	2739737
RPL27	6155	ribosomal protein L27	cytosol	Cellular component	-
CEMIP	57214	cell migration inducing protein, hyaluronan binding	hyalurononglucosaminidase activity	Molecular function	23509262
SMO	6608	smoothened, frizzled class receptor	plasma membrane	Cellular component	19304771
HCN1	348980	hyperpolarization activated cyclic nucleotide gated potassium channel 1	regulation of ion transmembrane transport	Biological process	-
EDNRB	1910	endothelin receptor type B	positive regulation of renal sodium excretion	Biological process	-
UBE2Q2	92912	ubiquitin-conjugating enzyme E2Q family member 2	protein K48-linked ubiquitination	Biological process	20061386
TP53	7157	tumor protein p53	determination of adult lifespan	Biological process	-
DLC1	10395	DLC1 Rho GTPase activating protein	negative regulation of Rho protein signal transduction	Biological process	16951145
TNK1	8711	tyrosine kinase, non-receptor, 1	protein phosphorylation	Biological process	8632913
HSPA1B	3304	heat shock 70kDa protein 1B	protein binding involved in protein folding	Molecular function	15603737
MPP2	4355	membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)	PDZ domain binding	Molecular function	-
HIST1H4G	8369	histone cluster 1, H4g	DNA binding	Molecular function	-
GLP1R	2740	glucagon-like peptide 1 receptor	cytosol	Cellular component	7589461
HAP1	9001	huntingtin-associated protein 1	autophagy	Biological process	-
H1F0	3005	H1 histone family, member 0	programmed cell death	Biological process	-
FOXP3	50943	forkhead box P3	sequence-specific DNA binding	Molecular function	11483607
PSMD10	5716	proteasome (prosome, macropain) 26S subunit, non-ATPase, 10	cellular nitrogen compound metabolic process	Biological process	-
LCORL	254251	ligand dependent nuclear receptor corepressor-like	regulation of transcription from RNA polymerase II promoter	Biological process	-
PECAM1	5175	platelet/endothelial cell adhesion molecule 1	platelet activation	Biological process	-
MTF1	4520	metal-regulatory transcription factor 1	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	9582278
TAT	6898	tyrosine aminotransferase	L-tyrosine:2-oxoglutarate aminotransferase activity	Molecular function	-
SLC27A4	10999	solute carrier family 27 (fatty acid transporter), member 4	medium-chain fatty acid transport	Biological process	-
STK3	6788	serine/threonine kinase 3	regulation of apoptotic process	Biological process	-
FEZF1	389549	FEZ family zinc finger 1	positive regulation of neuron differentiation	Biological process	-
SOCS1	8651	suppressor of cytokine signaling 1	protein kinase binding	Molecular function	9727029
CACNA1A	773	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	metal ion binding	Molecular function	-
FRZB	2487	frizzled-related protein	skeletal system development	Biological process	8824257
IL6R	3570	interleukin 6 receptor	monocyte chemotaxis	Biological process	10510402
CRB1	23418	crumbs family member 1, photoreceptor morphogenesis associated	protein binding	Molecular function	11927608
SEL1L3	23231	sel-1 suppressor of lin-12-like 3 (C. elegans)	nucleus	Cellular component	-
SPC25	57405	SPC25, NDC80 kinetochore complex component	cell division	Biological process	-
NFATC1	4772	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	calcium ion transport	Biological process	-
YWHAG	7532	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma	transcription initiation from RNA polymerase II promoter	Biological process	-
CH25H	9023	cholesterol 25-hydroxylase	fatty acid biosynthetic process	Biological process	-
SKP2	6502	S-phase kinase-associated protein 2, E3 ubiquitin protein ligase	mitotic cell cycle	Biological process	-
FGF2	2247	fibroblast growth factor 2 (basic)	positive regulation of cell proliferation	Biological process	8663044
SNCA	6622	synuclein, alpha (non A4 component of amyloid precursor)	negative regulation of mitochondrial electron transport, NADH to ubiquinone	Biological process	24252804
HSP90AA1	3320	heat shock protein 90kDa alpha (cytosolic), class A member 1	endocytic vesicle lumen	Cellular component	-
Sep-02	4735	septin 2	extracellular exosome	Cellular component	20458337
GRB2	2885	growth factor receptor-bound protein 2	protein kinase binding	Molecular function	20086093
ITGB8	3696	integrin, beta 8	negative regulation of gene expression	Biological process	24312400
ADGRF5	221395	adhesion G protein-coupled receptor F5	surfactant homeostasis	Biological process	-
UBE3B	89910	ubiquitin protein ligase E3B	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	-
RRAGA	10670	Ras-related GTP binding A	Gtr1-Gtr2 GTPase complex	Cellular component	-
MICAL1	64780	microtubule associated monooxygenase, calponin and LIM domain containing 1	oxidation-reduction process	Biological process	21864500
THSD1	55901	thrombospondin, type I, domain containing 1	cell surface	Cellular component	-
SMAD2	4087	SMAD family member 2	response to cholesterol	Biological process	17878231
APP	351	amyloid beta (A4) precursor protein	ciliary rootlet	Cellular component	-
HDAC7	51564	histone deacetylase 7	protein kinase C binding	Molecular function	20188095
DAZAP1	26528	DAZ associated protein 1	positive regulation of mRNA splicing, via spliceosome	Biological process	-
IQCB1	9657	IQ motif containing B1	protein binding	Molecular function	21565611
GOLGB1	2804	golgin B1	endoplasmic reticulum-Golgi intermediate compartment	Cellular component	15308636
LRRK2	120892	leucine-rich repeat kinase 2	clathrin binding	Molecular function	21307259
USP36	57602	ubiquitin specific peptidase 36	cysteine-type endopeptidase activity	Molecular function	-
ZFP28	140612	ZFP28 zinc finger protein	nucleus	Cellular component	-
ALS2	57679	amyotrophic lateral sclerosis 2 (juvenile)	growth cone	Cellular component	-
KIN	22944	Kin17 DNA and RNA binding protein	DNA binding	Molecular function	1923796
PIK3AP1	118788	phosphoinositide-3-kinase adaptor protein 1	positive regulation of phosphatidylinositol 3-kinase signaling	Biological process	-
KRT17	3872	keratin 17, type I	cell periphery	Cellular component	-
HEBP2	23593	heme binding protein 2	extracellular exosome	Cellular component	19056867
BTBD11	121551	BTB (POZ) domain containing 11	integral component of membrane	Cellular component	-
SNX1	6642	sorting nexin 1	retrograde transport, endosome to Golgi	Biological process	18088323
KANSL1	284058	KAT8 regulatory NSL complex subunit 1	histone acetyltransferase complex	Cellular component	20018852
MEF2A	4205	myocyte enhancer factor 2A	TRIF-dependent toll-like receptor signaling pathway	Biological process	-
RNF112	7732	ring finger protein 112	integral component of membrane	Cellular component	-
APEX1	328	APEX nuclease (multifunctional DNA repair enzyme) 1	transcription-coupled nucleotide-excision repair	Biological process	-
IFNW1	3467	interferon, omega 1	adaptive immune response	Biological process	-
HPN	3249	hepsin	nuclear membrane	Cellular component	15614436
SFN	2810	stratifin	signal transduction	Biological process	8515476
BIRC2	329	baculoviral IAP repeat containing 2	CD40 receptor complex	Cellular component	-
OR10K2	391107	olfactory receptor, family 10, subfamily K, member 2	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
AEN	64782	apoptosis enhancing nuclease	response to ionizing radiation	Biological process	16171785
GPSM1	26086	G-protein signaling modulator 1	regulation of G-protein coupled receptor protein signaling pathway	Biological process	-
NUP62	23636	nucleoporin 62kDa	intracellular membrane-bounded organelle	Cellular component	-
HSD3B1	3283	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1	steroid metabolic process	Biological process	-
KIT	3815	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	regulation of developmental pigmentation	Biological process	-
ECM2	1842	extracellular matrix protein 2, female organ and adipocyte specific	integrin binding	Molecular function	9790758
SLC9A8	23315	solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8	sodium ion transmembrane transport	Biological process	-
HDAC2	3066	histone deacetylase 2	sequence-specific DNA binding transcription factor activity	Molecular function	-
ZIC1	7545	Zic family member 1	cell differentiation	Biological process	-
SMC4	10051	structural maintenance of chromosomes 4	nucleus	Cellular component	11850403
BNIP3	664	BCL2/adenovirus E1B 19kDa interacting protein 3	autophagic cell death	Biological process	-
RNF32	140545	ring finger protein 32	aggresome	Cellular component	11890671
SERPINI1	5274	serpin peptidase inhibitor, clade I (neuroserpin), member 1	regulation of cell adhesion	Biological process	-
PPP4R4	57718	protein phosphatase 4, regulatory subunit 4	protein binding	Molecular function	18715871
SALL1	6299	spalt-like transcription factor 1	ventricular septum development	Biological process	-
LTBP4	8425	latent transforming growth factor beta binding protein 4	extracellular exosome	Cellular component	23376485
SYNE1	23345	spectrin repeat containing, nuclear envelope 1	establishment of nucleus localization	Biological process	-
SLC12A1	6557	solute carrier family 12 (sodium/potassium/chloride transporter), member 1	kidney development	Biological process	-
ATL2	64225	atlastin GTPase 2	protein binding	Molecular function	19665976
NPHP4	261734	nephronophthisis 4	negative regulation of canonical Wnt signaling pathway	Biological process	-
HIST1H4E	8367	histone cluster 1, H4e	protein heterodimerization activity	Molecular function	-
KMT2D	8085	lysine (K)-specific methyltransferase 2D	response to estrogen	Biological process	16603732
EXOC2	55770	exocyst complex component 2	membrane	Cellular component	19946888
P2RY1	5028	purinergic receptor P2Y, G-protein coupled, 1	adenosine receptor signaling pathway	Biological process	-
TGFBR3	7049	transforming growth factor, beta receptor III	positive regulation of transforming growth factor beta receptor signaling pathway	Biological process	-
DNAJC2	27000	DnaJ (Hsp40) homolog, subfamily C, member 2	negative regulation of DNA biosynthetic process	Biological process	-
HPSE	10855	heparanase	lysosomal lumen	Cellular component	-
TMBIM6	7009	transmembrane BAX inhibitor motif containing 6	membrane	Cellular component	19946888
OSBPL9	114883	oxysterol binding protein-like 9	lipid binding	Molecular function	-
PIK3CD	5293	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	B cell receptor signaling pathway	Biological process	20940048
SRPX2	27286	sushi-repeat containing protein, X-linked 2	single organismal cell-cell adhesion	Biological process	19065654
PRPF19	27339	pre-mRNA processing factor 19	cytoplasm	Cellular component	11435423
PSMB2	5690	proteasome (prosome, macropain) subunit, beta type, 2	gene expression	Biological process	-
CCL5	6352	chemokine (C-C motif) ligand 5	positive regulation of monocyte chemotaxis	Biological process	1699135
TCIRG1	10312	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3	cellular iron ion homeostasis	Biological process	-
DNAJA3	9093	DnaJ (Hsp40) homolog, subfamily A, member 3	skeletal muscle acetylcholine-gated channel clustering	Biological process	-
DNAJC3	5611	DnaJ (Hsp40) homolog, subfamily C, member 3	extracellular exosome	Cellular component	19199708
PLXNA3	55558	plexin A3	protein binding	Molecular function	20138877
CTDP1	9150	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1	cell division	Biological process	-
TPRA1	131601	transmembrane protein, adipocyte asscociated 1	G-protein coupled receptor activity	Molecular function	10342878
INSM2	84684	insulinoma-associated 2	cytoplasm	Cellular component	-
CXXC1	30827	CXXC finger protein 1	nuclear matrix	Cellular component	-
ZNF487	642819	zinc finger protein 487	nucleus	Cellular component	-
CYP4F2	8529	cytochrome P450, family 4, subfamily F, polypeptide 2	cytoplasm	Cellular component	10660572
KCNU1	157855	potassium channel, subfamily U, member 1	potassium channel activity	Molecular function	-
HCK	3055	HCK proto-oncogene, Src family tyrosine kinase	innate immune response	Biological process	-
TARBP2	6895	TAR (HIV-1) RNA binding protein 2	regulation of viral transcription	Biological process	11641396
SETD8	387893	SET domain containing (lysine methyltransferase) 8	transcription corepressor activity	Molecular function	18408754
GBP1	2633	guanylate binding protein 1, interferon-inducible	negative regulation of interleukin-2 secretion	Biological process	24337748
CHMP2A	27243	charged multivesicular body protein 2A	membrane invagination	Biological process	24878737
IQGAP2	10788	IQ motif containing GTPase activating protein 2	phosphatidylinositol-3,4,5-trisphosphate binding	Molecular function	22493426
ABCB6	10058	ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)	extracellular exosome	Cellular component	19056867
CADM1	23705	cell adhesion molecule 1	protein binding	Molecular function	12234973
AHSP	51327	alpha hemoglobin stabilizing protein	hemoglobin complex	Cellular component	12066189
FHIT	2272	fragile histidine triad	mitochondrion	Cellular component	-
MAG	4099	myelin associated glycoprotein	Schmidt-Lanterman incisure	Cellular component	-
WASF2	10163	WAS protein family, member 2	ameboidal-type cell migration	Biological process	-
HYAL2	8692	hyaluronoglucosaminidase 2	enzyme binding	Molecular function	19366691
NR3C1	2908	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	positive regulation of neuron apoptotic process	Biological process	-
IFNE	338376	interferon, epsilon	T cell activation involved in immune response	Biological process	-
PCGF1	84759	polycomb group ring finger 1	PcG protein complex	Cellular component	16943429
PRPF3	9129	pre-mRNA processing factor 3	mRNA splicing, via spliceosome	Biological process	9328476
CDK11A	728642	cyclin-dependent kinase 11A	regulation of cell growth	Biological process	10882096
TLR3	7098	toll-like receptor 3	positive regulation of type III interferon production	Biological process	-
WASL	8976	Wiskott-Aldrich syndrome-like	transcription, DNA-templated	Biological process	-
CSPG5	10675	chondroitin sulfate proteoglycan 5 (neuroglycan C)	chondroitin sulfate biosynthetic process	Biological process	-
SLC8A1	6546	solute carrier family 8 (sodium/calcium exchanger), member 1	calcium ion transport into cytosol	Biological process	-
KDM5C	8242	lysine (K)-specific demethylase 5C	zinc ion binding	Molecular function	-
FAN1	22909	FANCD2/FANCI-associated nuclease 1	nucleus	Cellular component	20603015
TESK2	10420	testis-specific kinase 2	protein kinase activity	Molecular function	10512679
SPATA2	9825	spermatogenesis associated 2	protein binding	Molecular function	25416956
CD276	80381	CD276 molecule	negative regulation of inflammatory response	Biological process	-
PARVA	55742	parvin, alpha	cell junction assembly	Biological process	-
FOXI1	2299	forkhead box I1	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	19214237
TRAF3IP2	10758	TRAF3 interacting protein 2	immunoglobulin secretion	Biological process	-
ATP13A1	57130	ATPase type 13A1	metabolic process	Biological process	-
GAGE2D	729408	G antigen 2D	protein binding	Molecular function	16189514
MAGEA3	4102	melanoma antigen family A3	negative regulation of protein processing	Biological process	12097332
GAPDHS	26330	glyceraldehyde-3-phosphate dehydrogenase, spermatogenic	protein binding	Molecular function	16820410
CORO1B	57175	coronin, actin binding protein, 1B	actin filament	Cellular component	18775315
AURKA	6790	aurora kinase A	ATP binding	Molecular function	-
CDIPT	10423	CDP-diacylglycerol--inositol 3-phosphatidyltransferase	alcohol binding	Molecular function	-
SLC26A6	65010	solute carrier family 26 (anion exchanger), member 6	secondary active sulfate transmembrane transporter activity	Molecular function	-
CYP26B1	56603	cytochrome P450, family 26, subfamily B, polypeptide 1	male meiosis	Biological process	-
PRNP	5621	prion protein	identical protein binding	Molecular function	16286452
TIAM2	26230	T-cell lymphoma invasion and metastasis 2	regulation of small GTPase mediated signal transduction	Biological process	-
COL8A1	1295	collagen, type VIII, alpha 1	extracellular exosome	Cellular component	23376485
SNX17	9784	sorting nexin 17	signal transduction	Biological process	-
PTK2B	2185	protein tyrosine kinase 2 beta	response to lithium ion	Biological process	-
KCNIP1	30820	Kv channel interacting protein 1	potassium channel regulator activity	Molecular function	10676964
ARPC3	10094	actin related protein 2/3 complex, subunit 3, 21kDa	lamellipodium	Cellular component	-
FAM98B	283742	family with sequence similarity 98, member B	nucleus	Cellular component	24608264
NAPSA	9476	napsin A aspartic peptidase	extracellular exosome	Cellular component	19056867
SULT1A3	6818	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3	aryl sulfotransferase activity	Molecular function	-
ATF5	22809	activating transcription factor 5	negative regulation of nucleic acid-templated transcription	Biological process	10373550
PDK4	5166	pyruvate dehydrogenase kinase, isozyme 4	regulation of fatty acid oxidation	Biological process	-
PRDX6	9588	peroxiredoxin 6	oxidation-reduction process	Biological process	-
MCCC2	64087	methylcrotonoyl-CoA carboxylase 2 (beta)	biotin metabolic process	Biological process	-
HMCES	56941	5-hydroxymethylcytosine (hmC) binding, ES cell-specific	DNA binding	Molecular function	-
FGB	2244	fibrinogen beta chain	extracellular matrix organization	Biological process	-
KDM5D	8284	lysine (K)-specific demethylase 5D	nucleoplasm	Cellular component	-
UBE2G1	7326	ubiquitin-conjugating enzyme E2G 1	ubiquitin protein ligase activity	Molecular function	-
RPH3A	22895	rabphilin 3A	phosphatidylinositol-4,5-bisphosphate binding	Molecular function	-
EGFR	1956	epidermal growth factor receptor	actin filament binding	Molecular function	14702346
ATF3	467	activating transcription factor 3	RNA polymerase II regulatory region sequence-specific DNA binding	Molecular function	2516827
SOD1	6647	superoxide dismutase 1, soluble	superoxide metabolic process	Biological process	-
PEX1	5189	peroxisomal biogenesis factor 1	protein C-terminus binding	Molecular function	16854980
GFM2	84340	G elongation factor, mitochondrial 2	GTPase activity	Molecular function	19716793
VILL	50853	villin-like	cytoskeleton organization	Biological process	-
ZNF738	148203	zinc finger protein 738	nucleus	Cellular component	-
RNASE10	338879	ribonuclease, RNase A family, 10 (non-active)	ribonuclease activity	Molecular function	-
GAL3ST2	64090	galactose-3-O-sulfotransferase 2	protein binding	Molecular function	25416956
NFKB1	4790	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	protein heterodimerization activity	Molecular function	18212740
SLC4A4	8671	solute carrier family 4 (sodium bicarbonate cotransporter), member 4	anion transmembrane transport	Biological process	-
GABBR1	2550	gamma-aminobutyric acid (GABA) B receptor, 1	synaptic transmission	Biological process	-
STK11	6794	serine/threonine kinase 11	p53 binding	Molecular function	11430832
HSPA1L	3305	heat shock 70kDa protein 1-like	protein binding	Molecular function	17184779
WWTR1	25937	WW domain containing transcription regulator 1	osteoblast differentiation	Biological process	-
CACNA1E	777	calcium channel, voltage-dependent, R type, alpha 1E subunit	high voltage-gated calcium channel activity	Molecular function	-
APOE	348	apolipoprotein E	response to reactive oxygen species	Biological process	11743999
RPL27	6155	ribosomal protein L27	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Biological process	-
MPO	4353	myeloperoxidase	metal ion binding	Molecular function	-
DLGAP5	9787	discs, large (Drosophila) homolog-associated protein 5	cytoplasm	Cellular component	-
KLHL20	27252	kelch-like family member 20	cytoskeleton organization	Biological process	10888605
PSMD7	5713	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	Biological process	-
OR2F2	135948	olfactory receptor, family 2, subfamily F, member 2	sensory perception of smell	Biological process	-
PAEP	5047	progestagen-associated endometrial protein	protein binding	Molecular function	25416956
GPX1	2876	glutathione peroxidase 1	response to glucose	Biological process	-
SAFB	6294	scaffold attachment factor B	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
ABCG5	64240	ATP-binding cassette, sub-family G (WHITE), member 5	response to nutrient	Biological process	-
CFL1	1072	cofilin 1 (non-muscle)	Rho protein signal transduction	Biological process	10436159
NDUFB10	4716	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa	mitochondrial electron transport, NADH to ubiquinone	Biological process	9878551
PTGIR	5739	prostaglandin I2 (prostacyclin) receptor (IP)	adenylate cyclase-activating G-protein coupled receptor signaling pathway	Biological process	20622039
HBM	3042	hemoglobin, mu	oxygen transport	Biological process	-
SLU7	10569	SLU7 splicing factor homolog (S. cerevisiae)	mRNA splicing, via spliceosome	Biological process	11991638
THEM4	117145	thioesterase superfamily member 4	palmitoyl-CoA hydrolase activity	Molecular function	22871024
ELN	2006	elastin	extracellular matrix organization	Biological process	-
SAA1	6288	serum amyloid A1	receptor-mediated endocytosis	Biological process	-
PAK1	5058	p21 protein (Cdc42/Rac)-activated kinase 1	ruffle membrane	Cellular component	-
ROR2	4920	receptor tyrosine kinase-like orphan receptor 2	plasma membrane	Cellular component	-
USP11	8237	ubiquitin specific peptidase 11	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological process	-
DCHS1	8642	dachsous cadherin-related 1	neural tube development	Biological process	-
STK3	6788	serine/threonine kinase 3	protein binding	Molecular function	14729613
RAPH1	65059	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1	protein binding	Molecular function	24076656
ASTL	431705	astacin-like metallo-endopeptidase (M12 family)	proteolysis	Biological process	15087446
AK4	205	adenylate kinase 4	ATP metabolic process	Biological process	19766732
RPS12	6206	ribosomal protein S12	structural constituent of ribosome	Molecular function	-
HDAC4	9759	histone deacetylase 4	negative regulation of myotube differentiation	Biological process	10983972
CCS	9973	copper chaperone for superoxide dismutase	intracellular copper ion transport	Biological process	9726962
MOS	4342	v-mos Moloney murine sarcoma viral oncogene homolog	negative regulation of metaphase/anaphase transition of meiotic cell cycle	Biological process	-
TPM1	7168	tropomyosin 1 (alpha)	cardiac muscle contraction	Biological process	11136687
TXN2	25828	thioredoxin 2	protein folding	Biological process	-
KLF2	10365	Kruppel-like factor 2	positive regulation of transcription from RNA polymerase II promoter	Biological process	20551324
UBE2U	148581	ubiquitin-conjugating enzyme E2U (putative)	ATP binding	Molecular function	-
GJA4	2701	gap junction protein, alpha 4, 37kDa	protein binding	Molecular function	23840749
PRKAR1A	5573	protein kinase, cAMP-dependent, regulatory, type I, alpha	negative regulation of cAMP-dependent protein kinase activity	Biological process	21812984
TBX6	6911	T-box 6	negative regulation of neuron maturation	Biological process	-
HSPA9	3313	heat shock 70kDa protein 9 (mortalin)	cytoplasm	Cellular component	7684501
KCNIP3	30818	Kv channel interacting protein 3, calsenilin	potassium channel activity	Molecular function	-
RNF169	254225	ring finger protein 169	nucleoplasm	Cellular component	-
GATA3	2625	GATA binding protein 3	positive regulation of transcription, DNA-templated	Biological process	-
NLRC4	58484	NLR family, CARD domain containing 4	inhibition of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	-
TFAP2C	7022	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	keratinocyte development	Biological process	-
NR1H3	10062	nuclear receptor subfamily 1, group H, member 3	zinc ion binding	Molecular function	-
HNF1B	6928	HNF1 homeobox B	epithelial cell proliferation	Biological process	-
NDN	4692	necdin, melanoma antigen (MAGE) family member	centrosome	Cellular component	-
SMAD1	4086	SMAD family member 1	cardiac muscle cell proliferation	Biological process	-
CASP8	841	caspase 8, apoptosis-related cysteine peptidase	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	Biological process	-
HOXA11	3207	homeobox A11	sequence-specific DNA binding	Molecular function	-
F2R	2149	coagulation factor II (thrombin) receptor	regulation of sensory perception of pain	Biological process	-
CD3E	916	CD3e molecule, epsilon (CD3-TCR complex)	G-protein coupled receptor signaling pathway	Biological process	8530500
PTK2B	2185	protein tyrosine kinase 2 beta	positive regulation of cytosolic calcium ion concentration	Biological process	-
GHRHR	2692	growth hormone releasing hormone receptor	response to glucocorticoid	Biological process	9482665
SERINC1	57515	serine incorporator 1	L-serine transport	Biological process	-
SMCP	4184	sperm mitochondria-associated cysteine-rich protein	protein binding	Molecular function	16189514
LTA4H	4048	leukotriene A4 hydrolase	leukotriene metabolic process	Biological process	-
NCF4	4689	neutrophil cytosolic factor 4, 40kDa	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	Biological process	-
DEFB103A	414325	defensin, beta 103A	defense response to bacterium	Biological process	-
UBE2D3	7323	ubiquitin-conjugating enzyme E2D 3	extracellular exosome	Cellular component	23533145
ADIPOQ	9370	adiponectin, C1Q and collagen domain containing	identical protein binding	Molecular function	10961870
VPS25	84313	vacuolar protein sorting 25 homolog (S. cerevisiae)	cytosol	Cellular component	-
MYO6	4646	myosin VI	unconventional myosin complex	Cellular component	9259267
PDHB	5162	pyruvate dehydrogenase (lipoamide) beta	protein binding	Molecular function	18206651
PIK3R5	23533	phosphoinositide-3-kinase, regulatory subunit 5	1-phosphatidylinositol-3-kinase regulator activity	Molecular function	-
IL2	3558	interleukin 2	extrinsic apoptotic signaling pathway in absence of ligand	Biological process	-
MEIS2	4212	Meis homeobox 2	eye development	Biological process	-
BIRC7	79444	baculoviral IAP repeat containing 7	nucleus	Cellular component	17294084
FBXO2	26232	F-box protein 2	ubiquitin-protein transferase activity	Molecular function	10531035
PINK1	65018	PTEN induced putative kinase 1	activation of mitophagy in response to mitochondrial depolarization	Biological process	20871098
KCNIP3	30818	Kv channel interacting protein 3, calsenilin	protein localization to plasma membrane	Biological process	-
RP2	6102	retinitis pigmentosa 2 (X-linked recessive)	plasma membrane	Cellular component	12417528
SIRT7	51547	sirtuin 7	positive regulation of transcription on exit from mitosis	Biological process	19174463
YES1	7525	YES proto-oncogene 1, Src family tyrosine kinase	cellular protein modification process	Biological process	2436037
SMIM17	147670	small integral membrane protein 17	integral component of membrane	Cellular component	-
FUS	2521	FUS RNA binding protein	cytoplasm	Cellular component	-
HIPK1	204851	homeodomain interacting protein kinase 1	positive regulation of cell proliferation	Biological process	-
FAT2	2196	FAT atypical cadherin 2	nucleus	Cellular component	-
NUP93	9688	nucleoporin 93kDa	nuclear membrane	Cellular component	15229283
PARK7	11315	parkinson protein 7	positive regulation of mitochondrion degradation	Biological process	24531622
MYH6	4624	myosin, heavy chain 6, cardiac muscle, alpha	actin binding	Molecular function	-
PKD2	5311	polycystic kidney disease 2 (autosomal dominant)	liver development	Biological process	11891195
PKD2	5311	polycystic kidney disease 2 (autosomal dominant)	regulation of cAMP metabolic process	Biological process	-
VDAC3	7419	voltage-dependent anion channel 3	extracellular exosome	Cellular component	19056867
PLCZ1	89869	phospholipase C, zeta 1	intracellular signal transduction	Biological process	-
ID2	3398	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	mammary gland epithelial cell proliferation	Biological process	-
HBE1	3046	hemoglobin, epsilon 1	blood coagulation	Biological process	-
DAND5	199699	DAN domain family member 5, BMP antagonist	determination of heart left/right asymmetry	Biological process	-
PRKAR2A	5576	protein kinase, cAMP-dependent, regulatory, type II, alpha	cAMP-dependent protein kinase inhibitor activity	Molecular function	21812984
WDR5	11091	WD repeat domain 5	transcription, DNA-templated	Biological process	-
GTF2F1	2962	general transcription factor IIF, polypeptide 1, 74kDa	catalytic activity	Molecular function	-
HSPD1	3329	heat shock 60kDa protein 1 (chaperonin)	cytoplasm	Cellular component	21328542
ADRBK1	156	adrenergic, beta, receptor kinase 1	cytoplasm	Cellular component	17986524
MCMBP	79892	minichromosome maintenance complex binding protein	MCM complex	Cellular component	17296731
SGPL1	8879	sphingosine-1-phosphate lyase 1	endoplasmic reticulum membrane	Cellular component	-
CYCS	54205	cytochrome c, somatic	apoptotic DNA fragmentation	Biological process	8689682
STAR	6770	steroidogenic acute regulatory protein	response to leptin	Biological process	-
POMC	5443	proopiomelanocortin	glucose homeostasis	Biological process	-
MANEA	79694	mannosidase, endo-alpha	protein N-linked glycosylation via asparagine	Biological process	-
DKK4	27121	dickkopf WNT signaling pathway inhibitor 4	cellular_component	Cellular component	-
KCNJ2	3759	potassium channel, inwardly rectifying subfamily J, member 2	positive regulation of potassium ion transmembrane transport	Biological process	-
SMAD3	4088	SMAD family member 3	positive regulation of chondrocyte differentiation	Biological process	-
PTPRG	5793	protein tyrosine phosphatase, receptor type, G	identical protein binding	Molecular function	19167335
BECN1	8678	beclin 1, autophagy related	defense response to virus	Biological process	-
T	6862	T, brachyury homolog (mouse)	SMAD protein signal transduction	Biological process	-
CSTA	1475	cystatin A (stefin A)	cornified envelope	Cellular component	10908733
TBX3	6926	T-box 3	blood vessel development	Biological process	-
IFNL2	282616	interferon, lambda 2	JAK-STAT cascade	Biological process	-
DNAJA2	10294	DnaJ (Hsp40) homolog, subfamily A, member 2	extracellular exosome	Cellular component	19056867
KAT6B	23522	K(lysine) acetyltransferase 6B	transcription, DNA-templated	Biological process	-
ME3	10873	malic enzyme 3, NADP(+)-dependent, mitochondrial	mitochondrial matrix	Cellular component	-
OR1B1	347169	olfactory receptor, family 1, subfamily B, member 1 (gene/pseudogene)	olfactory receptor activity	Molecular function	-
TRIM26	7726	tripartite motif containing 26	positive regulation of sequence-specific DNA binding transcription factor activity	Biological process	23077300
ERCC2	2068	excision repair cross-complementation group 2	DNA binding	Molecular function	-
CCL16	6360	chemokine (C-C motif) ligand 16	cell chemotaxis	Biological process	9642106
SPATA24	202051	spermatogenesis associated 24	protein homodimerization activity	Molecular function	-
USO1	8615	USO1 vesicle transport factor	membrane fusion	Biological process	-
AOX1	316	aldehyde oxidase 1	2 iron, 2 sulfur cluster binding	Molecular function	-
ATXN2L	11273	ataxin 2-like	regulation of cytoplasmic mRNA processing body assembly	Biological process	23209657
B4GALT7	11285	xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7	Golgi membrane	Cellular component	-
MED12L	116931	mediator complex subunit 12-like	transcription from RNA polymerase II promoter	Biological process	-
BCOR	54880	BCL6 corepressor	palate development	Biological process	17517692
KDR	3791	kinase insert domain receptor	sorting endosome	Cellular component	-
NDUFB2	4708	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa	respiratory electron transport chain	Biological process	-
ANKRD26	22852	ankyrin repeat domain 26	regulation of fatty acid metabolic process	Biological process	-
PVR	5817	poliovirus receptor	cell adhesion molecule binding	Molecular function	12913096
HOXA7	3204	homeobox A7	embryonic skeletal system morphogenesis	Biological process	-
Sep-11	55752	septin 11	synapse	Cellular component	-
WNT5A	7474	wingless-type MMTV integration site family, member 5A	extracellular region	Cellular component	-
NCS1	23413	neuronal calcium sensor 1	extracellular exosome	Cellular component	23376485
PHF8	23133	PHD finger protein 8	nuclear membrane	Cellular component	-
L3MBTL1	26013	l(3)mbt-like 1 (Drosophila)	regulation of cell cycle	Biological process	15566354
PGAM5	192111	phosphoglycerate mutase family member 5	protein complex binding	Molecular function	22265414
CHD9	80205	chromodomain helicase DNA binding protein 9	plasma membrane	Cellular component	-
TGOLN2	10618	trans-golgi network protein 2	protein binding	Molecular function	17474147
PSMB2	5690	proteasome (prosome, macropain) subunit, beta type, 2	protein binding	Molecular function	14733938
FABP6	2172	fatty acid binding protein 6, ileal	bile acid metabolic process	Biological process	-
VCAN	1462	versican	calcium ion binding	Molecular function	-
RBM4	5936	RNA binding motif protein 4	negative regulation of translational initiation	Biological process	19801630
RAB2B	84932	RAB2B, member RAS oncogene family	GTPase activity	Molecular function	-
OGT	8473	O-linked N-acetylglucosamine (GlcNAc) transferase	protein O-linked glycosylation	Biological process	23353889
YTHDC2	64848	YTH domain containing 2	RNA polymerase binding	Molecular function	21559518
WFDC10B	280664	WAP four-disulfide core domain 10B	peptidase inhibitor activity	Molecular function	-
LRRK2	120892	leucine-rich repeat kinase 2	dendrite	Cellular component	-
FAR2	55711	fatty acyl CoA reductase 2	ether lipid biosynthetic process	Biological process	-
SEC24B	10427	SEC24 family member B	intracellular protein transport	Biological process	-
STK17B	9262	serine/threonine kinase 17b	plasma membrane	Cellular component	-
HAS2	3037	hyaluronan synthase 2	atrioventricular canal development	Biological process	-
BIN1	274	bridging integrator 1	regulation of cell cycle arrest	Biological process	10412034
CP	1356	ceruloplasmin (ferroxidase)	transmembrane transport	Biological process	-
IL21	59067	interleukin 21	signal transduction	Biological process	11081504
TNFSF13B	10673	tumor necrosis factor (ligand) superfamily, member 13b	integral component of membrane	Cellular component	12867412
TLR9	54106	toll-like receptor 9	defense response to Gram-negative bacterium	Biological process	22427638
DDX59	83479	DEAD (Asp-Glu-Ala-Asp) box polypeptide 59	ATP-dependent RNA helicase activity	Molecular function	-
CREBRF	153222	CREB3 regulatory factor	positive regulation of protein transport	Biological process	18391022
IFIT3	3437	interferon-induced protein with tetratricopeptide repeats 3	cytokine-mediated signaling pathway	Biological process	-
RAD1	5810	RAD1 checkpoint DNA exonuclease	checkpoint clamp complex	Cellular component	-
MYCN	4613	v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog	DNA binding	Molecular function	10597290
PAX8	7849	paired box 8	metanephric epithelium development	Biological process	7856737
SLC25A17	10478	solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17	peroxisomal membrane	Cellular component	-
CEP68	23177	centrosomal protein 68kDa	nucleoplasm	Cellular component	-
SRSF4	6429	serine/arginine-rich splicing factor 4	RNA splicing, via transesterification reactions	Biological process	8321209
FZD4	8322	frizzled class receptor 4	positive regulation of sequence-specific DNA binding transcription factor activity	Biological process	14688793
ATP8A2	51761	ATPase, aminophospholipid transporter, class I, type 8A, member 2	aging	Biological process	-
PECAM1	5175	platelet/endothelial cell adhesion molecule 1	phagocytosis	Biological process	12110892
ALG13	79868	ALG13, UDP-N-acetylglucosaminyltransferase subunit	protein N-linked glycosylation via asparagine	Biological process	-
PTPN7	5778	protein tyrosine phosphatase, non-receptor type 7	cytoplasmic side of plasma membrane	Cellular component	10940933
METAP2	10988	methionyl aminopeptidase 2	poly(A) RNA binding	Molecular function	22658674
FBXO9	26268	F-box protein 9	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological process	23263282
LPAR1	1902	lysophosphatidic acid receptor 1	plasma membrane	Cellular component	-
PRKCA	5578	protein kinase C, alpha	inactivation of MAPK activity	Biological process	-
IGFBP5	3488	insulin-like growth factor binding protein 5	intracellular signal transduction	Biological process	-
IRF2	3660	interferon regulatory factor 2	type I interferon signaling pathway	Biological process	-
NPHS1	4868	nephrosis 1, congenital, Finnish type (nephrin)	spectrin binding	Molecular function	-
ZNF468	90333	zinc finger protein 468	nucleus	Cellular component	-
PGRMC1	10857	progesterone receptor membrane component 1	heme binding	Molecular function	-
NUDT6	11162	nudix (nucleoside diphosphate linked moiety X)-type motif 6	hydrolase activity	Molecular function	-
EIF2AK3	9451	eukaryotic translation initiation factor 2-alpha kinase 3	endoplasmic reticulum unfolded protein response	Biological process	19816510
NUDT16	131870	nudix (nucleoside diphosphate linked moiety X)-type motif 16	mRNA catabolic process	Biological process	21070968
GZMA	3001	granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)	cytolysis	Biological process	-
SMYD3	64754	SET and MYND domain containing 3	metal ion binding	Molecular function	-
PGAM4	441531	phosphoglycerate mutase family member 4	phosphoglycerate mutase activity	Molecular function	11961099
TBX1	6899	T-box 1	odontogenesis of dentin-containing tooth	Biological process	-
P2RX1	5023	purinergic receptor P2X, ligand gated ion channel, 1	signal transduction	Biological process	9565569
ALX1	8092	ALX homeobox 1	nucleus	Cellular component	23288509
ITGA3	3675	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	nephron development	Biological process	24621570
ELANE	1991	elastase, neutrophil expressed	negative regulation of chemokine biosynthetic process	Biological process	12223522
UBE2B	7320	ubiquitin-conjugating enzyme E2B	protein K63-linked ubiquitination	Biological process	20061386
NUDT21	11051	nudix (nucleoside diphosphate linked moiety X)-type motif 21	RNA binding	Molecular function	8626397
BAMBI	25805	BMP and activin membrane-bound inhibitor	cell migration	Biological process	19328798
THAP9	79725	THAP domain containing 9	transposition, DNA-mediated	Biological process	23349291
NSMAF	8439	neutral sphingomyelinase (N-SMase) activation associated factor	phospholipid binding	Molecular function	-
METTL21B	25895	methyltransferase like 21B	intracellular	Cellular component	-
UROD	7389	uroporphyrinogen decarboxylase	small molecule metabolic process	Biological process	-
CBX1	10951	chromobox homolog 1	chromocenter	Cellular component	-
PHGDH	26227	phosphoglycerate dehydrogenase	L-serine biosynthetic process	Biological process	-
RGS18	64407	regulator of G-protein signaling 18	positive regulation of GTPase activity	Biological process	-
LONP1	9361	lon peptidase 1, mitochondrial	mitochondrial heavy strand promoter sense binding	Molecular function	9485316
MYL6B	140465	myosin, light chain 6B, alkali, smooth muscle and non-muscle	calcium ion binding	Molecular function	-
TRAF6	7189	TNF receptor-associated factor 6, E3 ubiquitin protein ligase	positive regulation of protein ubiquitination	Biological process	22412986
HNF4A	3172	hepatocyte nuclear factor 4, alpha	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
DGKD	8527	diacylglycerol kinase, delta 130kDa	diacylglycerol metabolic process	Biological process	12200442
EED	8726	embryonic ectoderm development	transcription, DNA-templated	Biological process	-
KCNH2	3757	potassium channel, voltage gated eag related subfamily H, member 2	perinuclear region of cytoplasm	Cellular component	25281747
POLR1D	51082	polymerase (RNA) I polypeptide D, 16kDa	termination of RNA polymerase III transcription	Biological process	-
KDM5B	10765	lysine (K)-specific demethylase 5B	cytoplasm	Cellular component	-
CHRM1	1128	cholinergic receptor, muscarinic 1	signal transduction	Biological process	3443095
NT5C3A	51251	5'-nucleotidase, cytosolic IIIA	2'-phosphotransferase activity	Molecular function	10942414
LDLRAD4	753	low density lipoprotein receptor class A domain containing 4	negative regulation of transforming growth factor beta receptor signaling pathway	Biological process	24627487
MIP	4284	major intrinsic protein of lens fiber	calmodulin binding	Molecular function	-
CITED1	4435	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1	regulation of transcription from RNA polymerase II promoter	Biological process	9434189
POMC	5443	proopiomelanocortin	negative regulation of tumor necrosis factor production	Biological process	10233018
FOXP1	27086	forkhead box P1	T follicular helper cell differentiation	Biological process	-
GREM1	26585	gremlin 1, DAN family BMP antagonist	activation of transmembrane receptor protein tyrosine kinase activity	Biological process	-
GPI	2821	glucose-6-phosphate isomerase	carbohydrate metabolic process	Biological process	-
DIAPH1	1729	diaphanous-related formin 1	neuron projection development	Biological process	-
AKAP11	11215	A kinase (PRKA) anchor protein 11	microtubule organizing center	Cellular component	-
IGHG2	3501	immunoglobulin heavy constant gamma 2 (G2m marker)	antigen binding	Molecular function	-
INO80C	125476	INO80 complex subunit C	DNA repair	Biological process	-
MED1	5469	mediator complex subunit 1	intracellular steroid hormone receptor signaling pathway	Biological process	11867769
HTR2B	3357	5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled	G-protein alpha-subunit binding	Molecular function	15625277
SLC8A1	6546	solute carrier family 8 (sodium/calcium exchanger), member 1	calcium ion export	Biological process	19481548
OR8B8	26493	olfactory receptor, family 8, subfamily B, member 8	sensory perception of smell	Biological process	9119360
AOC1	26	amine oxidase, copper containing 1	amine metabolic process	Biological process	-
FYN	2534	FYN proto-oncogene, Src family tyrosine kinase	ATP binding	Molecular function	-
CREBZF	58487	CREB/ATF bZIP transcription factor	regulation of sequence-specific DNA binding transcription factor activity	Biological process	15705566
PDGFRB	5159	platelet-derived growth factor receptor, beta polypeptide	intrinsic component of plasma membrane	Cellular component	2554309
EIF3E	3646	eukaryotic translation initiation factor 3, subunit E	cytosol	Cellular component	-
SLC26A6	65010	solute carrier family 26 (anion exchanger), member 6	anion:anion antiporter activity	Molecular function	-
CCR2	729230	chemokine (C-C motif) receptor 2	negative regulation of adenylate cyclase activity	Biological process	8995400
SIRT1	23411	sirtuin 1	nuclear envelope	Cellular component	15469825
ITGB1BP1	9270	integrin beta 1 binding protein 1	integrin activation	Biological process	-
SGCZ	137868	sarcoglycan, zeta	sarcoglycan complex	Cellular component	17438352
UNC5A	90249	unc-5 homolog A (C. elegans)	plasma membrane	Cellular component	-
CIDEA	1149	cell death-inducing DFFA-like effector a	regulation of apoptotic process	Biological process	-
ZNF818P	390963	zinc finger protein 818, pseudogene	nucleus	Cellular component	-
WHSC1L1	54904	Wolf-Hirschhorn syndrome candidate 1-like 1	histone methylation	Biological process	16682010
VAMP4	8674	vesicle-associated membrane protein 4	Golgi membrane	Cellular component	9553086
ZNF618	114991	zinc finger protein 618	metal ion binding	Molecular function	-
DPP4	1803	dipeptidyl-peptidase 4	dipeptidyl-peptidase activity	Molecular function	10593948
VWA8	23078	von Willebrand factor A domain containing 8	ATP binding	Molecular function	-
RAB11B	9230	RAB11B, member RAS oncogene family	cell junction	Cellular component	-
GABRB2	2561	gamma-aminobutyric acid (GABA) A receptor, beta 2	chloride transmembrane transport	Biological process	-
SET	6418	SET nuclear proto-oncogene	perinuclear region of cytoplasm	Cellular component	11555662
HSP90AA1	3320	heat shock protein 90kDa alpha (cytosolic), class A member 1	positive regulation of lamellipodium assembly	Biological process	-
MAP2K1	5604	mitogen-activated protein kinase kinase 1	cell cycle arrest	Biological process	9765203
TIMM44	10469	translocase of inner mitochondrial membrane 44 homolog (yeast)	protein targeting to mitochondrion	Biological process	-
EXTL3	2137	exostosin-like glycosyltransferase 3	endoplasmic reticulum unfolded protein response	Biological process	-
Sep-07	989	septin 7	cytoplasm	Cellular component	-
MECOM	2122	MDS1 and EVI1 complex locus	in utero embryonic development	Biological process	-
MRPS6	64968	mitochondrial ribosomal protein S6	mitochondrial translation	Biological process	-
MECOM	2122	MDS1 and EVI1 complex locus	Golgi apparatus	Cellular component	-
OR52B4	143496	olfactory receptor, family 52, subfamily B, member 4 (gene/pseudogene)	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
ECT2	1894	epithelial cell transforming 2	apoptotic signaling pathway	Biological process	-
PRKACB	5567	protein kinase, cAMP-dependent, catalytic, beta	protein phosphorylation	Biological process	12420224
DNAH12	201625	dynein, axonemal, heavy chain 12	ATPase activity	Molecular function	-
GPHB5	122876	glycoprotein hormone beta 5	regulation of thyroid hormone mediated signaling pathway	Biological process	-
STX17	55014	syntaxin 17	mitochondrion	Cellular component	10930465
FUCA2	2519	fucosidase, alpha-L- 2, plasma	extracellular exosome	Cellular component	23376485
ADAM15	8751	ADAM metallopeptidase domain 15	integrin-mediated signaling pathway	Biological process	22505472
LAMA5	3911	laminin, alpha 5	endothelial cell differentiation	Biological process	11821406
HCAR2	338442	hydroxycarboxylic acid receptor 2	negative regulation of lipid catabolic process	Biological process	-
EGFR	1956	epidermal growth factor receptor	activation of phospholipase C activity	Biological process	12435727
AP1G1	164	adaptor-related protein complex 1, gamma 1 subunit	intracellular protein transport	Biological process	-
CCT8	10694	chaperonin containing TCP1, subunit 8 (theta)	microtubule	Cellular component	21525035
KRTAP21-2	337978	keratin associated protein 21-2	intermediate filament	Cellular component	-
AATF	26574	apoptosis antagonizing transcription factor	leucine zipper domain binding	Molecular function	10580117
KDM4A	9682	lysine (K)-specific demethylase 4A	methylated histone binding	Molecular function	22373579
CREBBP	1387	CREB binding protein	regulation of cellular response to heat	Biological process	-
COL5A2	1290	collagen, type V, alpha 2	SMAD binding	Molecular function	-
SLC26A5	375611	solute carrier family 26 (anion exchanger), member 5	regulation of membrane potential	Biological process	-
MKRN2	23609	makorin ring finger protein 2	protein binding	Molecular function	17500595
ZNF281	23528	zinc finger protein 281	nucleus	Cellular component	10448078
MED1	5469	mediator complex subunit 1	negative regulation of apoptotic process	Biological process	-
ARIH2	10425	ariadne RBR E3 ubiquitin protein ligase 2	hematopoietic stem cell proliferation	Biological process	16118314
LMNA	4000	lamin A/C	programmed cell death	Biological process	-
LAS1L	81887	LAS1-like (S. cerevisiae)	nucleolus	Cellular component	-
VEGFA	7422	vascular endothelial growth factor A	response to hypoxia	Biological process	16490744
PTP4A2	8073	protein tyrosine phosphatase type IVA, member 2	peptidyl-tyrosine dephosphorylation	Biological process	9514946
HS6ST1	9394	heparan sulfate 6-O-sulfotransferase 1	neuron development	Biological process	21700882
RBP2	5948	retinol binding protein 2, cellular	phototransduction, visible light	Biological process	-
CLDN9	9080	claudin 9	plasma membrane	Cellular component	-
EXOC6B	23233	exocyst complex component 6B	vesicle docking involved in exocytosis	Biological process	-
NAMPT	10135	nicotinamide phosphoribosyltransferase	small molecule metabolic process	Biological process	-
IL1B	3553	interleukin 1, beta	positive regulation of protein phosphorylation	Biological process	16477012
NPAT	4863	nuclear protein, ataxia-telangiectasia locus	nucleoplasm	Cellular component	-
ZNF645	158506	zinc finger protein 645	zinc ion binding	Molecular function	-
FKBP9	11328	FK506 binding protein 9, 63 kDa	endoplasmic reticulum	Cellular component	-
CDK6	1021	cyclin-dependent kinase 6	T cell differentiation in thymus	Biological process	-
CHRM1	1128	cholinergic receptor, muscarinic 1	positive regulation of cell proliferation	Biological process	2739737
FGF6	2251	fibroblast growth factor 6	signal transduction	Biological process	2649847
SP7	121340	Sp7 transcription factor	regulation of transcription from RNA polymerase II promoter	Biological process	11792318
TNFRSF6B	8771	tumor necrosis factor receptor superfamily, member 6b, decoy	negative regulation of apoptotic process	Biological process	9872321
CDK13	8621	cyclin-dependent kinase 13	alternative mRNA splicing, via spliceosome	Biological process	16721827
B3GNT8	374907	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8	extracellular exosome	Cellular component	23533145
TNFSF13B	10673	tumor necrosis factor (ligand) superfamily, member 13b	receptor binding	Molecular function	10908663
VAX2	25806	ventral anterior homeobox 2	retina development in camera-type eye	Biological process	-
TEX14	56155	testis expressed 14	male meiosis	Biological process	-
WNT11	7481	wingless-type MMTV integration site family, member 11	negative regulation of cell migration	Biological process	20103596
RIPPLY1	92129	ripply transcriptional repressor 1	Notch signaling pathway	Biological process	-
SPX	80763	spexin hormone	positive regulation of systemic arterial blood pressure	Biological process	-
CHRAC1	54108	chromatin accessibility complex 1	DNA binding	Molecular function	10880450
CDC42	998	cell division cycle 42	epithelial-mesenchymal cell signaling	Biological process	-
LMX1B	4010	LIM homeobox transcription factor 1, beta	trabecular meshwork development	Biological process	-
NAA10	8260	N(alpha)-acetyltransferase 10, NatA catalytic subunit	peptide alpha-N-acetyltransferase activity	Molecular function	19480662
DOK5	55816	docking protein 5	insulin receptor binding	Molecular function	-
YES1	7525	YES proto-oncogene 1, Src family tyrosine kinase	receptor binding	Molecular function	-
CYTH3	9265	cytohesin 3	establishment of epithelial cell polarity	Biological process	-
ZNF818P	390963	zinc finger protein 818, pseudogene	metal ion binding	Molecular function	-
F11R	50848	F11 receptor	cytoplasmic vesicle	Cellular component	-
TAF9	6880	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa	positive regulation of cell growth	Biological process	15899866
TRIM16L	147166	tripartite motif containing 16-like	cytoplasm	Cellular component	-
RAB11FIP3	9727	RAB11 family interacting protein 3 (class II)	midbody	Cellular component	15601896
TMOD2	29767	tropomodulin 2 (neuronal)	growth cone	Cellular component	-
SMC3	9126	structural maintenance of chromosomes 3	protein sumoylation	Biological process	-
SP1	6667	Sp1 transcription factor	lung development	Biological process	-
NRG3	10718	neuregulin 3	activation of transmembrane receptor protein tyrosine kinase activity	Biological process	9275162
C1QTNF2	114898	C1q and tumor necrosis factor related protein 2	extracellular space	Cellular component	-
PRDX1	5052	peroxiredoxin 1	peroxidase activity	Molecular function	-
TESK1	7016	testis-specific kinase 1	protein serine/threonine kinase activity	Molecular function	-
CDHR2	54825	cadherin-related family member 2	homophilic cell adhesion via plasma membrane adhesion molecules	Biological process	-
MDM4	4194	MDM4, p53 regulator	G0 to G1 transition	Biological process	12101245
SGOL1	151648	shugoshin-like 1 (S. pombe)	chromosome segregation	Biological process	16580887
NCBP1	4686	nuclear cap binding protein subunit 1, 80kDa	spliceosomal snRNP assembly	Biological process	-
FAM20C	56975	family with sequence similarity 20, member C	protein binding	Molecular function	25789606
ARHGEF28	64283	Rho guanine nucleotide exchange factor (GEF) 28	cytosol	Cellular component	-
ZBTB45	84878	zinc finger and BTB domain containing 45	regulation of transcription, DNA-templated	Biological process	-
PHACTR3	116154	phosphatase and actin regulator 3	negative regulation of catalytic activity	Biological process	-
MUC4	4585	mucin 4, cell surface associated	membrane	Cellular component	10920259
TRIP11	9321	thyroid hormone receptor interactor 11	regulation of nucleic acid-templated transcription	Biological process	9256431
RPS4Y1	6192	ribosomal protein S4, Y-linked 1	gene expression	Biological process	-
ZNF613	79898	zinc finger protein 613	transcription, DNA-templated	Biological process	-
CACNA1A	773	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	positive regulation of cytosolic calcium ion concentration	Biological process	-
RNF8	9025	ring finger protein 8, E3 ubiquitin protein ligase	spermatid development	Biological process	-
RAB1A	5861	RAB1A, member RAS oncogene family	endocytosis	Biological process	21303926
SFRP1	6422	secreted frizzled-related protein 1	convergent extension involved in somitogenesis	Biological process	-
DGKH	160851	diacylglycerol kinase, eta	protein oligomerization	Biological process	12810723
SIRT1	23411	sirtuin 1	nucleus	Cellular component	-
DPAGT1	1798	dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)	membrane	Cellular component	8179616
FBLN5	10516	fibulin 5	extracellular space	Cellular component	20551380
SLC6A4	6532	solute carrier family 6 (neurotransmitter transporter), member 4	protein homodimerization activity	Molecular function	-
GTF2H3	2967	general transcription factor IIH, polypeptide 3, 34kDa	phosphorylation of RNA polymerase II C-terminal domain	Biological process	-
FBXO5	26271	F-box protein 5	metal ion binding	Molecular function	-
SDSL	113675	serine dehydratase-like	biological_process	Biological process	-
CCT8	10694	chaperonin containing TCP1, subunit 8 (theta)	cellular protein metabolic process	Biological process	-
JUP	3728	junction plakoglobin	skin development	Biological process	-
PLA2G4F	255189	phospholipase A2, group IVF	arachidonic acid secretion	Biological process	-
PTK2	5747	protein tyrosine kinase 2	regulation of protein phosphorylation	Biological process	19913511
SNRPD2	6633	small nuclear ribonucleoprotein D2 polypeptide 16.5kDa	spliceosomal snRNP assembly	Biological process	-
OCRL	4952	oculocerebrorenal syndrome of Lowe	extracellular exosome	Cellular component	23376485
ARX	170302	aristaless related homeobox	chromatin binding	Molecular function	-
ARL4C	10123	ADP-ribosylation factor-like 4C	metabolic process	Biological process	10462049
HPS6	79803	Hermansky-Pudlak syndrome 6	endoplasmic reticulum	Cellular component	-
AADAT	51166	aminoadipate aminotransferase	small molecule metabolic process	Biological process	-
PPARG	5468	peroxisome proliferator-activated receptor gamma	cellular response to retinoic acid	Biological process	-
GTF2B	2959	general transcription factor IIB	nucleoplasm	Cellular component	-
CUL5	8065	cullin 5	viral process	Biological process	-
RHOU	58480	ras homolog family member U	actin cytoskeleton organization	Biological process	-
H1FNT	341567	H1 histone family, member N, testis-specific	nuclear chromatin	Cellular component	15710904
C12orf10	60314	chromosome 12 open reading frame 10	locomotory exploration behavior	Biological process	-
CHMP2B	25978	charged multivesicular body protein 2B	lysosome	Cellular component	16041373
BCL2L12	83596	BCL2-like 12 (proline rich)	positive regulation of transcription from RNA polymerase II promoter	Biological process	22262180
CHRM3	1131	cholinergic receptor, muscarinic 3	receptor activity	Molecular function	10940357
PLEKHG6	55200	pleckstrin homology domain containing, family G (with RhoGef domain) member 6	spindle pole	Cellular component	-
CLN8	2055	ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)	neurofilament cytoskeleton organization	Biological process	-
SH3PXD2A	9644	SH3 and PX domains 2A	podosome	Cellular component	18417249
NKX2-1	7080	NK2 homeobox 1	negative regulation of transcription, DNA-templated	Biological process	-
RAD23A	5886	RAD23 homolog A (S. cerevisiae)	positive regulation of viral genome replication	Biological process	20614012
INPP5E	56623	inositol polyphosphate-5-phosphatase, 72 kDa	phospholipid metabolic process	Biological process	-
CAMK2A	815	calcium/calmodulin-dependent protein kinase II alpha	plasma membrane	Cellular component	-
ZAP70	7535	zeta-chain (TCR) associated protein kinase 70kDa	innate immune response	Biological process	-
CAT	847	catalase	heme binding	Molecular function	10656833
HMGB2	3148	high mobility group box 2	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	Biological process	-
XRN2	22803	5'-3' exoribonuclease 2	cell growth	Biological process	-
IKBKG	8517	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	transcription, DNA-templated	Biological process	-
HIST1H2BF	8343	histone cluster 1, H2bf	nucleoplasm	Cellular component	-
TBC1D3B	414059	TBC1 domain family, member 3B	GTPase activator activity	Molecular function	-
DDX20	11218	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20	protein domain specific binding	Molecular function	-
TIMM17B	10245	translocase of inner mitochondrial membrane 17 homolog B (yeast)	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	Molecular function	-
UBE2V2	7336	ubiquitin-conjugating enzyme E2 variant 2	cell proliferation	Biological process	9418904
PSMB11	122706	proteasome (prosome, macropain) subunit, beta type, 11	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
EDN1	1906	endothelin 1	cell-cell signaling	Biological process	12379507
STK39	27347	serine threonine kinase 39	negative regulation of potassium ion transmembrane transporter activity	Biological process	24393035
PLXNA1	5361	plexin A1	semaphorin receptor complex	Cellular component	19909241
SCN2A	6326	sodium channel, voltage gated, type II alpha subunit	membrane depolarization during action potential	Biological process	-
MRPL45	84311	mitochondrial ribosomal protein L45	mitochondrial inner membrane	Cellular component	-
CD1D	912	CD1d molecule	T cell selection	Biological process	14500461
SCGB1C2	653486	secretoglobin, family 1C, member 2	extracellular region	Cellular component	-
PLAG1	5324	pleiomorphic adenoma gene 1	nucleus	Cellular component	-
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	apical part of cell	Cellular component	-
PPP5C	5536	protein phosphatase 5, catalytic subunit	membrane	Cellular component	-
EIF2S3	1968	eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa	gene expression	Biological process	-
RBBP4	5928	retinoblastoma binding protein 4	gene expression	Biological process	-
RUVBL1	8607	RuvB-like AAA ATPase 1	DNA helicase activity	Molecular function	9843967
MDM2	4193	MDM2 proto-oncogene, E3 ubiquitin protein ligase	p53 binding	Molecular function	15053879
RAB1C	441400	RAB1C, member RAS oncogene family pseudogene	membrane	Cellular component	-
ZPBP2	124626	zona pellucida binding protein 2	extracellular region	Cellular component	-
PPP1R15A	23645	protein phosphatase 1, regulatory subunit 15A	endoplasmic reticulum	Cellular component	12556489
KIF3B	9371	kinesin family member 3B	cytosol	Cellular component	-
GJA3	2700	gap junction protein, alpha 3, 46kDa	gap junction channel activity	Molecular function	-
CYR61	3491	cysteine-rich, angiogenic inducer, 61	insulin-like growth factor binding	Molecular function	-
UCMA	221044	upper zone of growth plate and cartilage matrix associated	extracellular space	Cellular component	-
GNAI2	2771	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	GTP binding	Molecular function	-
TMEM89	440955	transmembrane protein 89	integral component of membrane	Cellular component	-
SNTA1	6640	syntrophin, alpha 1	lateral plasma membrane	Cellular component	21164104
RNF43	54894	ring finger protein 43	plasma membrane	Cellular component	-
PCDHB15	56121	protocadherin beta 15	homophilic cell adhesion via plasma membrane adhesion molecules	Biological process	-
MIF	4282	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	negative regulation of myeloid cell apoptotic process	Biological process	-
DYNLL1	8655	dynein, light chain, LC8-type 1	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	Biological process	-
ADRB1	153	adrenoceptor beta 1	cell-cell signaling	Biological process	-
OSBP	5007	oxysterol binding protein	lipid transport	Biological process	-
JMJD7	100137047	jumonji domain containing 7	protein binding	Molecular function	25416956
SLC12A9	56996	solute carrier family 12, member 9	plasma membrane	Cellular component	-
TMEM204	79652	transmembrane protein 204	smooth muscle cell differentiation	Biological process	-
FOXN4	121643	forkhead box N4	retina layer formation	Biological process	-
Sep-06	23157	septin 6	cytokinesis	Biological process	11809673
SST	6750	somatostatin	response to amino acid	Biological process	-
MAB21L1	4081	mab-21-like 1 (C. elegans)	positive regulation of cell proliferation	Biological process	-
EIF4E1B	253314	eukaryotic translation initiation factor 4E family member 1B	regulation of translation	Biological process	-
COL15A1	1306	collagen, type XV, alpha 1	integral component of membrane	Cellular component	10891348
PLXNA1	5361	plexin A1	extracellular exosome	Cellular component	20458337
NKX2-6	137814	NK2 homeobox 6	pharyngeal system development	Biological process	-
IGKV2-40	28916	immunoglobulin kappa variable 2-40	immune response	Biological process	5586923
GATA1	2623	GATA binding protein 1 (globin transcription factor 1)	erythrocyte differentiation	Biological process	7678994
DAG1	1605	dystroglycan 1 (dystrophin-associated glycoprotein 1)	postsynaptic membrane	Cellular component	-
PSMD13	5719	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	meiosis I	Biological process	-
FBXO43	286151	F-box protein 43	nucleus	Cellular component	-
EPHB4	2050	EPH receptor B4	extracellular region	Cellular component	-
SLC4A9	83697	solute carrier family 4, sodium bicarbonate cotransporter, member 9	sodium:bicarbonate symporter activity	Molecular function	-
ZNF230	7773	zinc finger protein 230	regulation of transcription, DNA-templated	Biological process	-
TPP1	1200	tripeptidyl peptidase I	endoplasmic reticulum unfolded protein response	Biological process	-
KDM1B	221656	lysine (K)-specific demethylase 1B	zinc ion binding	Molecular function	-
MED1	5469	mediator complex subunit 1	androgen biosynthetic process	Biological process	19497978
JUND	3727	jun D proto-oncogene	osteoblast development	Biological process	-
NCF2	4688	neutrophil cytosolic factor 2	Rac GTPase binding	Molecular function	-
PKD1L2	114780	polycystic kidney disease 1-like 2 (gene/pseudogene)	integral component of membrane	Cellular component	-
ADORA1	134	adenosine A1 receptor	negative regulation of acute inflammatory response	Biological process	-
ACVR1	90	activin A receptor, type I	protein phosphorylation	Biological process	12065756
MAGEA2	4101	melanoma antigen family A2	signal transduction by p53 class mediator	Biological process	16847267
ITGB3	3690	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	tube development	Biological process	19267251
BCDIN3D	144233	BCDIN3 domain containing	RNA methyltransferase activity	Molecular function	23063121
HIVEP1	3096	human immunodeficiency virus type I enhancer binding protein 1	transcription, DNA-templated	Biological process	-
EGF	1950	epidermal growth factor	positive regulation of DNA binding	Biological process	-
ACTR6	64431	ARP6 actin-related protein 6 homolog (yeast)	protein binding	Molecular function	15647280
IST1	9798	increased sodium tolerance 1 homolog (yeast)	cytokinesis	Biological process	19525971
SUDS3	64426	suppressor of defective silencing 3 homolog (S. cerevisiae)	apoptotic process	Biological process	-
HECW1	23072	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1	negative regulation of canonical Wnt signaling pathway	Biological process	-
APOBEC2	10930	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2	cytidine deaminase activity	Molecular function	10403781
STK3	6788	serine/threonine kinase 3	protein phosphorylation	Biological process	20086174
FIG4	9896	FIG4 phosphoinositide 5-phosphatase	vacuole organization	Biological process	-
SLC9A6	10479	solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6	recycling endosome membrane	Cellular component	11940519
Sep-02	4735	septin 2	cell cortex	Cellular component	-
GPR63	81491	G protein-coupled receptor 63	molecular_function	Molecular function	-
GRPEL1	80273	GrpE-like 1, mitochondrial (E. coli)	unfolded protein binding	Molecular function	11311562
GLYATL3	389396	glycine-N-acyltransferase-like 3	glycine N-acyltransferase activity	Molecular function	-
GATA3	2625	GATA binding protein 3	RNA polymerase II core promoter sequence-specific DNA binding	Molecular function	-
CYP2F1	1572	cytochrome P450, family 2, subfamily F, polypeptide 1	aromatase activity	Molecular function	-
ADIG	149685	adipogenin	white fat cell differentiation	Biological process	15567149
SBNO1	55206	strawberry notch homolog 1 (Drosophila)	regulation of transcription, DNA-templated	Biological process	-
MED7	9443	mediator complex subunit 7	transcription coactivator activity	Molecular function	9989412
HMGA2	8091	high mobility group AT-hook 2	MH2 domain binding	Molecular function	18832382
TGFBR1	7046	transforming growth factor, beta receptor 1	membrane	Cellular component	-
DLX3	1747	distal-less homeobox 3	blood vessel development	Biological process	-
KAT5	10524	K(lysine) acetyltransferase 5	Piccolo NuA4 histone acetyltransferase complex	Cellular component	14966270
PHKA2	5256	phosphorylase kinase, alpha 2 (liver)	calmodulin binding	Molecular function	-
SECTM1	6398	secreted and transmembrane 1	Golgi apparatus	Cellular component	9480746
ERCC3	2071	excision repair cross-complementation group 3	transcription from RNA polymerase II promoter	Biological process	-
NPS	594857	neuropeptide S	positive regulation of synaptic transmission, glutamatergic	Biological process	-
WNT9B	7484	wingless-type MMTV integration site family, member 9B	regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	Biological process	-
WDR55	54853	WD repeat domain 55	ribosomal large subunit biogenesis	Biological process	-
MAZ	4150	MYC-associated zinc finger protein (purine-binding transcription factor)	cytoplasm	Cellular component	-
IRF6	3664	interferon regulatory factor 6	cytoplasm	Cellular component	16049006
RNF121	55298	ring finger protein 121	Golgi membrane	Cellular component	-
OR5I1	10798	olfactory receptor, family 5, subfamily I, member 1	sensory perception of smell	Biological process	-
ERVK-25	100862683	endogenous retrovirus group K, member 25	structural molecule activity	Molecular function	-
TCEAL4	79921	transcription elongation factor A (SII)-like 4	regulation of transcription, DNA-templated	Biological process	-
UFD1L	7353	ubiquitin fusion degradation 1 like (yeast)	ubiquitin-specific protease activity	Molecular function	9063746
RELN	5649	reelin	positive regulation of TOR signaling	Biological process	-
MAFG	4097	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G	blood coagulation	Biological process	-
PACS2	23241	phosphofurin acidic cluster sorting protein 2	mitochondrion	Cellular component	-
ST13	6767	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	chaperone cofactor-dependent protein refolding	Biological process	-
GOLGA4	2803	golgin A4	cytoplasm	Cellular component	-
GUCY1A3	2982	guanylate cyclase 1, soluble, alpha 3	positive regulation of cGMP biosynthetic process	Biological process	-
HABP2	3026	hyaluronan binding protein 2	extracellular region	Cellular component	14718574
RBM22	55696	RNA binding motif protein 22	nucleotide binding	Molecular function	-
PTH	5741	parathyroid hormone	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity	Molecular function	17696759
RAMP2	10266	receptor (G protein-coupled) activity modifying protein 2	negative regulation of endothelial cell apoptotic process	Biological process	18097473
SCN10A	6336	sodium channel, voltage gated, type X alpha subunit	neuronal action potential	Biological process	-
STAR	6770	steroidogenic acute regulatory protein	cellular response to glucose stimulus	Biological process	-
RPS2	6187	ribosomal protein S2	cytosol	Cellular component	-
PRKDC	5591	protein kinase, DNA-activated, catalytic polypeptide	DNA binding	Molecular function	-
CHD8	57680	chromodomain helicase DNA binding protein 8	negative regulation of transcription, DNA-templated	Biological process	18378692
ZNF221	7638	zinc finger protein 221	DNA binding	Molecular function	-
LYPD1	116372	LY6/PLAUR domain containing 1	plasma membrane	Cellular component	-
BICD1	636	bicaudal D homolog 1 (Drosophila)	perinuclear region of cytoplasm	Cellular component	20089649
IGF2BP2	10644	insulin-like growth factor 2 mRNA binding protein 2	cytoplasm	Cellular component	-
PANX2	56666	pannexin 2	cell-cell signaling	Biological process	-
APOA1	335	apolipoprotein A-I	negative regulation of very-low-density lipoprotein particle remodeling	Biological process	14967812
UBB	7314	ubiquitin B	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
PIP5K1A	8394	phosphatidylinositol-4-phosphate 5-kinase, type I, alpha	phosphatidylinositol biosynthetic process	Biological process	-
PLXND1	23129	plexin D1	semaphorin-plexin signaling pathway	Biological process	-
KIF3A	11127	kinesin family member 3A	cytosol	Cellular component	-
RAB3IP	117177	RAB3A interacting protein	Rab guanyl-nucleotide exchange factor activity	Molecular function	-
RPL29	6159	ribosomal protein L29	viral life cycle	Biological process	-
SYNE2	23224	spectrin repeat containing, nuclear envelope 2	protein binding	Molecular function	15671068
LEF1	51176	lymphoid enhancer-binding factor 1	forebrain neuroblast division	Biological process	-
TATDN2	9797	TatD DNase domain containing 2	nucleic acid phosphodiester bond hydrolysis	Biological process	-
CBFB	865	core-binding factor, beta subunit	myeloid cell differentiation	Biological process	-
LRRC17	10234	leucine rich repeat containing 17	negative regulation of osteoclast differentiation	Biological process	-
GPT	2875	glutamic-pyruvate transaminase (alanine aminotransferase)	L-alanine:2-oxoglutarate aminotransferase activity	Molecular function	1931970
MLN	4295	motilin	cell-cell signaling	Biological process	10381885
GHR	2690	growth hormone receptor	positive regulation of tyrosine phosphorylation of Stat3 protein	Biological process	2825030
CR2	1380	complement component (3d/Epstein Barr virus) receptor 2	complement receptor mediated signaling pathway	Biological process	-
JMJD1C	221037	jumonji domain containing 1C	chromatin modification	Biological process	-
NAT10	55226	N-acetyltransferase 10 (GCN5-related)	poly(A) RNA binding	Molecular function	22658674
PAFAH1B2	5049	platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)	protein homodimerization activity	Molecular function	-
DYNLL2	140735	dynein, light chain, LC8-type 2	nucleus	Cellular component	21630459
APOM	55937	apolipoprotein M	integral component of plasma membrane	Cellular component	10531326
ARHGAP26	23092	Rho GTPase activating protein 26	positive regulation of GTPase activity	Biological process	10908648
NDRG1	10397	N-myc downstream regulated 1	plasma membrane	Cellular component	12432451
CDK2	1017	cyclin-dependent kinase 2	mitotic nuclear division	Biological process	-
KDM6B	23135	lysine (K)-specific demethylase 6B	beta-catenin binding	Molecular function	-
RSRC1	51319	arginine/serine-rich coiled-coil 1	RNA splicing	Biological process	15798186
DR1	1810	down-regulator of transcription 1, TBP-binding (negative cofactor 2)	protein binding	Molecular function	18838386
CNTNAP2	26047	contactin associated protein-like 2	membrane	Cellular component	10624965
OR10G9	219870	olfactory receptor, family 10, subfamily G, member 9	sensory perception of smell	Biological process	-
APOC2	344	apolipoprotein C-II	extracellular space	Cellular component	10727238
NEK2	4751	NIMA-related kinase 2	ATP binding	Molecular function	-
DPAGT1	1798	dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)	intracellular membrane-bounded organelle	Cellular component	12872255
PPP2R4	5524	protein phosphatase 2A activator, regulatory subunit 4	nucleoplasm	Cellular component	-
FKBP10	60681	FK506 binding protein 10, 65 kDa	cytoplasm	Cellular component	-
CREB3	10488	cAMP responsive element binding protein 3	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	Biological process	16940180
NKX2-4	644524	NK2 homeobox 4	cellular_component	Cellular component	-
PCK2	5106	phosphoenolpyruvate carboxykinase 2 (mitochondrial)	gluconeogenesis	Biological process	-
FCER1G	2207	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	antigen processing and presentation of exogenous peptide antigen via MHC class II	Biological process	-
ATXN1L	342371	ataxin 1-like	nucleolus	Cellular component	-
CLRN1	7401	clarin 1	visual perception	Biological process	-
PDGFRA	5156	platelet-derived growth factor receptor, alpha polypeptide	protein complex	Cellular component	24190966
CRYGD	1421	crystallin, gamma D	lens fiber cell differentiation	Biological process	-
BCAR1	9564	breast cancer anti-estrogen resistance 1	cytoplasm	Cellular component	-
BIRC2	329	baculoviral IAP repeat containing 2	transcription, DNA-templated	Biological process	-
ANKS1B	56899	ankyrin repeat and sterile alpha motif domain containing 1B	postsynaptic density	Cellular component	-
PSMA2	5683	proteasome (prosome, macropain) subunit, alpha type, 2	viral process	Biological process	-
ACTA2	59	actin, alpha 2, smooth muscle, aorta	response to virus	Biological process	16548883
UFSP1	402682	UFM1-specific peptidase 1 (non-functional)	biological_process	Biological process	-
HIST4H4	121504	histone cluster 4, H4	protein binding	Molecular function	10220385
PPA1	5464	pyrophosphatase (inorganic) 1	cytosol	Cellular component	-
CPSF6	11052	cleavage and polyadenylation specific factor 6, 68kDa	mRNA polyadenylation	Biological process	20695905
CAMK2D	817	calcium/calmodulin-dependent protein kinase II delta	calcium channel complex	Cellular component	12676814
NR1D2	9975	nuclear receptor subfamily 1, group D, member 2	protein binding	Molecular function	17892483
HLA-DMA	3108	major histocompatibility complex, class II, DM alpha	cell surface	Cellular component	22247549
NDUFB8	4714	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa	mitochondrial inner membrane	Cellular component	-
FAHD2B	151313	fumarylacetoacetate hydrolase domain containing 2B	metal ion binding	Molecular function	-
MED1	5469	mediator complex subunit 1	ventricular trabecula myocardium morphogenesis	Biological process	-
LHX2	9355	LIM homeobox 2	nucleus	Cellular component	-
PPP1R9B	84687	protein phosphatase 1, regulatory subunit 9B	protein phosphatase type 1 complex	Cellular component	11278317
CLDN12	9069	claudin 12	bicellular tight junction assembly	Biological process	-
PKMYT1	9088	protein kinase, membrane associated tyrosine/threonine 1	ATP binding	Molecular function	-
GNAS	2778	GNAS complex locus	post-embryonic body morphogenesis	Biological process	-
TNP2	7142	transition protein 2 (during histone to protamine replacement)	binding of sperm to zona pellucida	Biological process	-
GATA3	2625	GATA binding protein 3	response to virus	Biological process	20583921
NOP58	51602	NOP58 ribonucleoprotein	rRNA modification	Biological process	-
MPI	4351	mannose phosphate isomerase	GDP-mannose biosynthetic process	Biological process	-
FZD2	2535	frizzled class receptor 2	G-protein coupled receptor signaling pathway	Biological process	-
SLC14A2	8170	solute carrier family 14 (urea transporter), member 2	urea transport	Biological process	8647271
HOXB6	3216	homeobox B6	anterior/posterior pattern specification	Biological process	-
SRF	6722	serum response factor (c-fos serum response element-binding transcription factor)	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
FGF18	8817	fibroblast growth factor 18	nucleolus	Cellular component	-
OR2C1	4993	olfactory receptor, family 2, subfamily C, member 1	integral component of membrane	Cellular component	-
RELA	5970	v-rel avian reticuloendotheliosis viral oncogene homolog A	positive regulation of miRNA metabolic process	Biological process	22357537
NPC1	4864	Niemann-Pick disease, type C1	Golgi apparatus	Cellular component	-
CCNE2	9134	cyclin E2	regulation of cyclin-dependent protein serine/threonine kinase activity	Biological process	9840943
XYLT1	64131	xylosyltransferase I	protein xylosyltransferase activity	Molecular function	11099377
ASUN	55726	asunder spermatogenesis regulator	cell division	Biological process	-
DNPH1	10591	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	cytoplasm	Cellular component	-
NFKB1	4790	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	positive regulation of lipid storage	Biological process	16938301
KLHL9	55958	kelch-like family member 9	Cul3-RING ubiquitin ligase complex	Cellular component	17543862
SMC1A	8243	structural maintenance of chromosomes 1A	cellular protein metabolic process	Biological process	-
KMT2A	4297	lysine (K)-specific methyltransferase 2A	sequence-specific DNA binding transcription factor activity	Molecular function	10821850
OR13C5	138799	olfactory receptor, family 13, subfamily C, member 5	G-protein coupled receptor activity	Molecular function	-
TRIM5	85363	tripartite motif containing 5	regulation of lipopolysaccharide-mediated signaling pathway	Biological process	21512573
NEO1	4756	neogenin 1	axon guidance	Biological process	-
LMNA	4000	lamin A/C	nucleus	Cellular component	-
IGKV1-5	28299	immunoglobulin kappa variable 1-5	regulation of immune response	Biological process	-
ZNF85	7639	zinc finger protein 85	protein binding	Molecular function	25416956
HIST1H4D	8360	histone cluster 1, H4d	membrane	Cellular component	19946888
ZBTB26	57684	zinc finger and BTB domain containing 26	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	-
PLVAP	83483	plasmalemma vesicle associated protein	perinuclear region of cytoplasm	Cellular component	-
WT1	7490	Wilms tumor 1	visceral serous pericardium development	Biological process	10101119
SPTY2D1	144108	SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)	cellular_component	Cellular component	-
SMC3	9126	structural maintenance of chromosomes 3	spindle pole	Cellular component	11590136
EP300	2033	E1A binding protein p300	activating transcription factor binding	Molecular function	20590529
DHRS4	10901	dehydrogenase/reductase (SDR family) member 4	alcohol metabolic process	Biological process	18571493
GABARAPL1	23710	GABA(A) receptor-associated protein like 1	protein binding	Molecular function	16189514
ECE1	1889	endothelin converting enzyme 1	vesicle	Cellular component	9449382
POU1F1	5449	POU class 1 homeobox 1	transcription corepressor activity	Molecular function	-
HAS2	3037	hyaluronan synthase 2	cellular response to platelet-derived growth factor stimulus	Biological process	17324121
PITX2	5308	paired-like homeodomain 2	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	-
RPL13	6137	ribosomal protein L13	nucleolus	Cellular component	-
LRP12	29967	low density lipoprotein receptor-related protein 12	coated pit	Cellular component	-
PIK3C3	5289	phosphatidylinositol 3-kinase, catalytic subunit type 3	early endosome to late endosome transport	Biological process	14617358
WDFY3	23001	WD repeat and FYVE domain containing 3	inclusion body	Cellular component	20168092
CDKN1B	1027	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	nucleoplasm	Cellular component	-
XPA	7507	xeroderma pigmentosum, complementation group A	nucleotide-excision repair, DNA damage removal	Biological process	-
NUP214	8021	nucleoporin 214kDa	carbohydrate metabolic process	Biological process	-
SERPINB10	5273	serpin peptidase inhibitor, clade B (ovalbumin), member 10	activation of mitophagy in response to mitochondrial depolarization	Biological process	22020285
LHX2	9355	LIM homeobox 2	mesoderm development	Biological process	-
RALB	5899	v-ral simian leukemia viral oncogene homolog B	negative regulation of protein binding	Biological process	24056301
BTK	695	Bruton agammaglobulinemia tyrosine kinase	ATP binding	Molecular function	11913944
GMPS	8833	guanine monphosphate synthase	purine ribonucleoside monophosphate biosynthetic process	Biological process	-
TFAP2B	7021	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	kidney development	Biological process	-
GRK5	2869	G protein-coupled receptor kinase 5	tachykinin receptor signaling pathway	Biological process	17986524
AP1M2	10053	adaptor-related protein complex 1, mu 2 subunit	membrane organization	Biological process	-
IMPA2	3613	inositol(myo)-1(or 4)-monophosphatase 2	small molecule metabolic process	Biological process	-
TNK2	10188	tyrosine kinase, non-receptor, 2	extrinsic component of cytoplasmic side of plasma membrane	Cellular component	-
AXIN1	8312	axin 1	positive regulation of GTPase activity	Biological process	-
KATNB1	10300	katanin p80 (WD repeat containing) subunit B 1	centrosome	Cellular component	-
NUP62	23636	nucleoporin 62kDa	gene expression	Biological process	-
HLA-B	3106	major histocompatibility complex, class I, B	regulation of dendritic cell differentiation	Biological process	20008523
GRIA4	2893	glutamate receptor, ionotropic, AMPA 4	ionotropic glutamate receptor activity	Molecular function	-
SMS	6611	spermine synthase	small molecule metabolic process	Biological process	-
PDE1B	5153	phosphodiesterase 1B, calmodulin-dependent	signal transduction	Biological process	-
AKT1S1	84335	AKT1 substrate 1 (proline-rich)	protein binding	Molecular function	12524439
ALB	213	albumin	platelet activation	Biological process	-
NEIL2	252969	nei endonuclease VIII-like 2 (E. coli)	hydrolase activity, hydrolyzing N-glycosyl compounds	Molecular function	-
CALD1	800	caldesmon 1	actin cap	Cellular component	-
SLC35E3	55508	solute carrier family 35, member E3	nucleotide-sugar transmembrane transporter activity	Molecular function	-
CLCA4	22802	chloride channel accessory 4	integral component of plasma membrane	Cellular component	10437792
SALL2	6297	spalt-like transcription factor 2	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
CBX1	10951	chromobox homolog 1	chromatin	Cellular component	11101528
DLG5	9231	discs, large homolog 5 (Drosophila)	protein binding	Molecular function	23624079
ZG16B	124220	zymogen granule protein 16B	carbohydrate binding	Molecular function	-
NUDT5	11164	nudix (nucleoside diphosphate linked moiety X)-type motif 5	ADP-ribose diphosphatase activity	Molecular function	-
FGF9	2254	fibroblast growth factor 9	extracellular exosome	Cellular component	23376485
AJUBA	84962	ajuba LIM protein	microtubule organizing center	Cellular component	-
ATP6V0B	533	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b	phagosome maturation	Biological process	-
RPS18	6222	ribosomal protein S18	ribosome	Cellular component	8441687
TGFB3	7043	transforming growth factor, beta 3	identical protein binding	Molecular function	18243111
RYR1	6261	ryanodine receptor 1 (skeletal)	cellular response to caffeine	Biological process	-
PTGR2	145482	prostaglandin reductase 2	extracellular exosome	Cellular component	23376485
NDRG2	57447	NDRG family member 2	extracellular exosome	Cellular component	19199708
TRAF3IP1	26146	TNF receptor-associated factor 3 interacting protein 1	intraciliary transport particle B	Cellular component	-
PDX1	3651	pancreatic and duodenal homeobox 1	response to drug	Biological process	-
FAM63A	55793	family with sequence similarity 63, member A	biological_process	Biological process	-
OR13A1	79290	olfactory receptor, family 13, subfamily A, member 1	integral component of plasma membrane	Cellular component	-
MMAA	166785	methylmalonic aciduria (cobalamin deficiency) cblA type	hydrolase activity	Molecular function	-
EPB42	2038	erythrocyte membrane protein band 4.2	ATP binding	Molecular function	8608138
PDCD1LG2	80380	programmed cell death 1 ligand 2	plasma membrane	Cellular component	-
C9orf114	51490	chromosome 9 open reading frame 114	condensed chromosome kinetochore	Cellular component	-
NOVA2	4858	neuro-oncological ventral antigen 2	RNA binding	Molecular function	10735272
CSF1R	1436	colony stimulating factor 1 receptor	mammary gland duct morphogenesis	Biological process	15117969
SEMA4G	57715	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G	protein binding	Molecular function	25416956
GJA5	2702	gap junction protein, alpha 5, 40kDa	regulation of ventricular cardiac muscle cell membrane depolarization	Biological process	-
COPG2	26958	coatomer protein complex, subunit gamma 2	intra-Golgi vesicle-mediated transport	Biological process	11056392
GAD2	2572	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)	perinuclear region of cytoplasm	Cellular component	-
FAM20C	56975	family with sequence similarity 20, member C	protein serine/threonine kinase activity	Molecular function	22582013
KIF14	9928	kinesin family member 14	activation of protein kinase activity	Biological process	24784001
KLF10	7071	Kruppel-like factor 10	circadian rhythm	Biological process	-
EIF3I	8668	eukaryotic translation initiation factor 3, subunit I	extracellular exosome	Cellular component	20458337
CTCF	10664	CCCTC-binding factor (zinc finger protein)	chromatin modification	Biological process	-
POM121	9883	POM121 transmembrane nucleoporin	endoplasmic reticulum membrane	Cellular component	-
ZC3H8	84524	zinc finger CCCH-type containing 8	protein binding	Molecular function	23932780
NTAN1	123803	N-terminal asparagine amidase	nucleus	Cellular component	-
TGFB1	7040	transforming growth factor, beta 1	platelet alpha granule lumen	Cellular component	-
C16orf89	146556	chromosome 16 open reading frame 89	cytosol	Cellular component	20578903
DLG5	9231	discs, large homolog 5 (Drosophila)	negative regulation of cell proliferation	Biological process	9738934
EEF1D	1936	eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)	mRNA transcription	Biological process	21597468
OPHN1	4983	oligophrenin 1	phospholipid binding	Molecular function	18954304
USP17L4	645402	ubiquitin specific peptidase 17-like family member 4	endoplasmic reticulum	Cellular component	-
MCAM	4162	melanoma cell adhesion molecule	integral component of membrane	Cellular component	-
THRAP3	9967	thyroid hormone receptor associated protein 3	positive regulation of transcription, DNA-templated	Biological process	10198638
PEG10	23089	paternally expressed 10	apoptotic process	Biological process	-
TJP1	7082	tight junction protein 1	programmed cell death	Biological process	-
TAB1	10454	TGF-beta activated kinase 1/MAP3K7 binding protein 1	stress-activated MAPK cascade	Biological process	-
OR5C1	392391	olfactory receptor, family 5, subfamily C, member 1	sensory perception of smell	Biological process	-
GPR32P1	2855	G protein-coupled receptor 32, pseudogene 1	plasma membrane	Cellular component	-
PCDHB2	56133	protocadherin beta 2	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	Biological process	11322959
S100A14	57402	S100 calcium binding protein A14	cytoplasm	Cellular component	-
CHRNA2	1135	cholinergic receptor, nicotinic, alpha 2 (neuronal)	acetylcholine-activated cation-selective channel activity	Molecular function	8906617
PLCD3	113026	phospholipase C, delta 3	small molecule metabolic process	Biological process	-
PIK3C2G	5288	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma	small molecule metabolic process	Biological process	-
PRDM10	56980	PR domain containing 10	nucleus	Cellular component	-
HMGB2	3148	high mobility group box 2	positive regulation of megakaryocyte differentiation	Biological process	19965638
NRG2	9542	neuregulin 2	Fc-epsilon receptor signaling pathway	Biological process	-
SPRR2A	6700	small proline-rich protein 2A	keratinocyte differentiation	Biological process	8325635
FSTL3	10272	follistatin-like 3 (secreted glycoprotein)	neuron projection terminus	Cellular component	-
MGEA5	10724	meningioma expressed antigen 5 (hyaluronidase)	positive regulation of mitochondrial depolarization	Biological process	-
PACRG	135138	PARK2 co-regulated	alpha-tubulin binding	Molecular function	14532270
FEZF1	389549	FEZ family zinc finger 1	neuron migration	Biological process	-
ALS2	57679	amyotrophic lateral sclerosis 2 (juvenile)	neuromuscular junction development	Biological process	-
F2	2147	coagulation factor II (thrombin)	post-translational protein modification	Biological process	-
FABP1	2168	fatty acid binding protein 1, liver	cellular response to hypoxia	Biological process	16175609
FASLG	356	Fas ligand (TNF superfamily, member 6)	cell-cell signaling	Biological process	7826947
LTB4R	1241	leukotriene B4 receptor	leukotriene B4 receptor activity	Molecular function	-
FTCD	10841	formimidoyltransferase cyclodeaminase	tetrahydrofolate interconversion	Biological process	-
DICER1	23405	dicer 1, ribonuclease type III	conversion of ds siRNA to ss siRNA involved in RNA interference	Biological process	19701182
EDNRA	1909	endothelin receptor type A	enteric nervous system development	Biological process	-
NKX2-5	1482	NK2 homeobox 5	negative regulation of canonical Wnt signaling pathway	Biological process	-
SLC26A4	5172	solute carrier family 26 (anion exchanger), member 4	inorganic anion transport	Biological process	10192399
PPARGC1A	10891	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	response to statin	Biological process	-
FGF8	2253	fibroblast growth factor 8 (androgen-induced)	innate immune response	Biological process	-
UQCC2	84300	ubiquinol-cytochrome c reductase complex assembly factor 2	mitochondrial nucleoid	Cellular component	19643811
FXYD4	53828	FXYD domain containing ion transport regulator 4	potassium ion transmembrane transport	Biological process	-
MAP1LC3B	81631	microtubule-associated protein 1 light chain 3 beta	organelle membrane	Cellular component	12740394
TEKT2	27285	tektin 2 (testicular)	nucleus	Cellular component	21630459
RPS6KA5	9252	ribosomal protein S6 kinase, 90kDa, polypeptide 5	toll-like receptor 4 signaling pathway	Biological process	-
PLG	5340	plasminogen	apolipoprotein binding	Molecular function	16480936
ITGA11	22801	integrin, alpha 11	plasma membrane	Cellular component	-
THSD1	55901	thrombospondin, type I, domain containing 1	extracellular region	Cellular component	-
DDX47	51202	DEAD (Asp-Glu-Ala-Asp) box polypeptide 47	mRNA processing	Biological process	-
TRIM14	9830	tripartite motif containing 14	innate immune response	Biological process	18248090
RASSF3	283349	Ras association (RalGDS/AF-6) domain family member 3	cytoplasm	Cellular component	-
MTF1	4520	metal-regulatory transcription factor 1	response to oxidative stress	Biological process	-
CCL26	10344	chemokine (C-C motif) ligand 26	cell-cell signaling	Biological process	10373330
CD3E	916	CD3e molecule, epsilon (CD3-TCR complex)	positive regulation of T cell proliferation	Biological process	12110186
IL23A	51561	interleukin 23, alpha subunit p19	positive regulation of osteoclast differentiation	Biological process	17888176
ESCO2	157570	establishment of sister chromatid cohesion N-acetyltransferase 2	nuclear pericentric heterochromatin	Cellular component	-
MSH6	2956	mutS homolog 6	nuclear chromatin	Cellular component	-
AR	367	androgen receptor	protein complex	Cellular component	18468998
PPIP5K2	23262	diphosphoinositol pentakisphosphate kinase 2	diphosphoinositol-pentakisphosphate kinase activity	Molecular function	-
IFT74	80173	intraflagellar transport 74	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
NLGN4Y	22829	neuroligin 4, Y-linked	synapse assembly	Biological process	-
UQCR10	29796	ubiquinol-cytochrome c reductase, complex III subunit X	hydrogen ion transmembrane transport	Biological process	8592474
VDAC1	7416	voltage-dependent anion channel 1	transmembrane transport	Biological process	-
EPHA5	2044	EPH receptor A5	regulation of insulin secretion involved in cellular response to glucose stimulus	Biological process	-
TNFSF12	8742	tumor necrosis factor (ligand) superfamily, member 12	protein binding	Molecular function	14961121
DRAP1	10589	DR1-associated protein 1 (negative cofactor 2 alpha)	sequence-specific DNA binding	Molecular function	-
FAM120B	84498	family with sequence similarity 120B	transcription, DNA-templated	Biological process	-
TNFSF11	8600	tumor necrosis factor (ligand) superfamily, member 11	positive regulation of corticotropin-releasing hormone secretion	Biological process	19940926
OR2L5	81466	olfactory receptor, family 2, subfamily L, member 5	integral component of membrane	Cellular component	-
AHCTF1	25909	AT hook containing transcription factor 1	nucleus	Cellular component	-
LITAF	9516	lipopolysaccharide-induced TNF factor	plasma membrane	Cellular component	16118794
KATNAL2	83473	katanin p60 subunit A-like 2	microtubule binding	Molecular function	-
LEP	3952	leptin	regulation of blood pressure	Biological process	-
HOXD11	3237	homeobox D11	embryonic forelimb morphogenesis	Biological process	-
ATF2	1386	activating transcription factor 2	protein heterodimerization activity	Molecular function	-
NKX6-1	4825	NK6 homeobox 1	positive regulation of neuron differentiation	Biological process	-
HLA-C	3107	major histocompatibility complex, class I, C	cytokine-mediated signaling pathway	Biological process	-
GLI2	2736	GLI family zinc finger 2	notochord regression	Biological process	-
HAL	3034	histidine ammonia-lyase	histidine catabolic process	Biological process	-
ST14	6768	suppression of tumorigenicity 14 (colon carcinoma)	extracellular exosome	Cellular component	23376485
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	apoptotic process	Biological process	-
RAMP2	10266	receptor (G protein-coupled) activity modifying protein 2	receptor internalization	Biological process	10882736
CASK	8573	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	protein serine/threonine kinase activity	Molecular function	-
MYD88	4615	myeloid differentiation primary response 88	identical protein binding	Molecular function	11544529
UBAP2L	9898	ubiquitin associated protein 2-like	PcG protein complex	Cellular component	25185265
SF3B6	51639	splicing factor 3b, subunit 6, 14kDa	RNA splicing	Biological process	-
TUBB2B	347733	tubulin, beta 2B class IIb	cytoplasm	Cellular component	-
F2RL2	2151	coagulation factor II (thrombin) receptor-like 2	response to wounding	Biological process	9087410
DGKH	160851	diacylglycerol kinase, eta	metal ion binding	Molecular function	-
SGPP1	81537	sphingosine-1-phosphate phosphatase 1	small molecule metabolic process	Biological process	-
AGTR2	186	angiotensin II receptor, type 2	positive regulation of cytokine secretion	Biological process	-
HEY2	23493	hes-related family bHLH transcription factor with YRPW motif 2	Notch signaling involved in heart development	Biological process	12372254
IL2RG	3561	interleukin 2 receptor, gamma	interleukin-2 binding	Molecular function	-
CDCA7L	55536	cell division cycle associated 7-like	positive regulation of cell proliferation	Biological process	15994933
DTX3	196403	deltex 3, E3 ubiquitin ligase	ligase activity	Molecular function	-
DKK1	22943	dickkopf WNT signaling pathway inhibitor 1	negative regulation of peptidyl-serine phosphorylation	Biological process	20723538
DLGAP2	9228	discs, large (Drosophila) homolog-associated protein 2	neuron-neuron synaptic transmission	Biological process	9694864
CGN	57530	cingulin	myosin complex	Cellular component	-
BCAT2	587	branched chain amino-acid transaminase 2, mitochondrial	small molecule metabolic process	Biological process	-
KIR2DL3	3804	killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3	antigen binding	Molecular function	9059894
MIOX	55586	myo-inositol oxygenase	NADP binding	Molecular function	-
PTK7	5754	protein tyrosine kinase 7 (inactive)	establishment of planar polarity	Biological process	-
FOXI1	2299	forkhead box I1	nucleus	Cellular component	19214237
ATIC	471	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	cerebral cortex development	Biological process	-
POU1F1	5449	POU class 1 homeobox 1	positive regulation of inositol trisphosphate biosynthetic process	Biological process	-
MRPL28	10573	mitochondrial ribosomal protein L28	mitochondrial inner membrane	Cellular component	-
BST2	684	bone marrow stromal cell antigen 2	response to interferon-beta	Biological process	-
EZH2	2146	enhancer of zeste 2 polycomb repressive complex 2 subunit	histone methyltransferase activity	Molecular function	15385962
MED10	84246	mediator complex subunit 10	RNA polymerase II transcription cofactor activity	Molecular function	-
PARVA	55742	parvin, alpha	regulation of cell shape	Biological process	-
VEGFA	7422	vascular endothelial growth factor A	positive regulation of cell migration	Biological process	17470632
BHMG1	388553	basic helix-loop-helix and HMG box domain containing 1	nucleus	Cellular component	-
CMTM3	123920	CKLF-like MARVEL transmembrane domain containing 3	positive regulation of B cell receptor signaling pathway	Biological process	-
MED17	9440	mediator complex subunit 17	thyroid hormone receptor binding	Molecular function	10198638
PDE6A	5145	phosphodiesterase 6A, cGMP-specific, rod, alpha	metal ion binding	Molecular function	-
ATXN1	6310	ataxin 1	nuclear RNA export factor complex	Cellular component	15615787
LAG3	3902	lymphocyte-activation gene 3	external side of plasma membrane	Cellular component	-
ZNF697	90874	zinc finger protein 697	metal ion binding	Molecular function	-
AGPAT6	137964	1-acylglycerol-3-phosphate O-acyltransferase 6	phosphatidic acid biosynthetic process	Biological process	-
H2AFY	9555	H2A histone family, member Y	nucleus	Cellular component	-
MSRB2	22921	methionine sulfoxide reductase B2	mitochondrion	Cellular component	14699060
MDH2	4191	malate dehydrogenase 2, NAD (mitochondrial)	extracellular exosome	Cellular component	19056867
NDNF	79625	neuron-derived neurotrophic factor	positive regulation of neuron projection development	Biological process	20969804
TPSD1	23430	tryptase delta 1	serine-type peptidase activity	Molecular function	9920877
SMAD1	4086	SMAD family member 1	sequence-specific DNA binding transcription factor activity	Molecular function	9389648
ARHGAP21	57584	Rho GTPase activating protein 21	GTPase activator activity	Molecular function	-
GRK6	2870	G protein-coupled receptor kinase 6	G-protein coupled receptor kinase activity	Molecular function	-
BCDIN3D	144233	BCDIN3 domain containing	protein binding	Molecular function	25416956
PSMC1	5700	proteasome (prosome, macropain) 26S subunit, ATPase, 1	negative regulation of apoptotic process	Biological process	-
ELP4	26610	elongator acetyltransferase complex subunit 4	nucleoplasm	Cellular component	-
CIC	23152	capicua transcriptional repressor	chromatin binding	Molecular function	-
SAT1	6303	spermidine/spermine N1-acetyltransferase 1	polyamine biosynthetic process	Biological process	-
POLR3F	10621	polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa	protein binding	Molecular function	16169070
NCOR1	9611	nuclear receptor corepressor 1	cholesterol homeostasis	Biological process	-
CBX4	8535	chromobox homolog 4	ligase activity	Molecular function	-
ATP6V0E2	155066	ATPase, H+ transporting V0 subunit e2	proton-transporting ATPase activity, rotational mechanism	Molecular function	-
PITX2	5308	paired-like homeodomain 2	male gonad development	Biological process	-
ZNF696	79943	zinc finger protein 696	nucleus	Cellular component	-
LRRN4CL	221091	LRRN4 C-terminal like	integral component of membrane	Cellular component	-
RAB11A	8766	RAB11A, member RAS oncogene family	multivesicular body assembly	Biological process	15634213
MTCL1	23255	microtubule crosslinking factor 1	protein binding	Molecular function	23902687
VEGFA	7422	vascular endothelial growth factor A	proteinaceous extracellular matrix	Cellular component	14570917
MRPS31	10240	mitochondrial ribosomal protein S31	mitochondrion	Cellular component	-
NUP155	9631	nucleoporin 155kDa	viral life cycle	Biological process	-
WNT2	7472	wingless-type MMTV integration site family member 2	mammary gland epithelium development	Biological process	8168088
HSD17B7	51478	hydroxysteroid (17-beta) dehydrogenase 7	3-keto sterol reductase activity	Molecular function	-
FDXR	2232	ferredoxin reductase	ferredoxin-NADP+ reductase activity	Molecular function	2845396
RPL39	6170	ribosomal protein L39	translational elongation	Biological process	-
DIS3L2	129563	DIS3 like 3'-5' exoribonuclease 2	rRNA catabolic process	Biological process	-
MAGI2	9863	membrane associated guanylate kinase, WW and PDZ domain containing 2	nerve growth factor signaling pathway	Biological process	-
ESR1	2099	estrogen receptor 1	signal transduction	Biological process	10749889
CREB3	10488	cAMP responsive element binding protein 3	cytosol	Cellular component	15001559
CREBBP	1387	CREB binding protein	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	21539536
PTPN11	5781	protein tyrosine phosphatase, non-receptor type 11	glucose homeostasis	Biological process	-
KIAA0101	9768	KIAA0101	perinuclear region of cytoplasm	Cellular component	21673012
SWAP70	23075	SWAP switching B-cell complex 70kDa subunit	nucleus	Cellular component	-
OR6X1	390260	olfactory receptor, family 6, subfamily X, member 1	olfactory receptor activity	Molecular function	-
SMCP	4184	sperm mitochondria-associated cysteine-rich protein	molecular_function	Molecular function	-
BIRC2	329	baculoviral IAP repeat containing 2	response to cAMP	Biological process	-
MSX2	4488	msh homeobox 2	enamel mineralization	Biological process	-
MYO1B	4430	myosin IB	perinuclear region of cytoplasm	Cellular component	21666684
MAPK12	6300	mitogen-activated protein kinase 12	cytoplasm	Cellular component	-
PTGDR2	11251	prostaglandin D2 receptor 2	prostaglandin J receptor activity	Molecular function	-
PRTFDC1	56952	phosphoribosyl transferase domain containing 1	hypoxanthine metabolic process	Biological process	-
EIF5AL1	143244	eukaryotic translation initiation factor 5A-like 1	translational frameshifting	Biological process	-
EIF2B3	8891	eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa	positive regulation of GTPase activity	Biological process	15054402
SLC34A2	10568	solute carrier family 34 (type II sodium/phosphate cotransporter), member 2	integral component of membrane	Cellular component	10610722
ACOT4	122970	acyl-CoA thioesterase 4	very long-chain fatty acid metabolic process	Biological process	16940157
SLC2A3	6515	solute carrier family 2 (facilitated glucose transporter), member 3	hexose transport	Biological process	-
JAK3	3718	Janus kinase 3	protein tyrosine kinase activity	Molecular function	-
ATP2A2	488	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	epidermis development	Biological process	10080178
DEFA5	1670	defensin, alpha 5, Paneth cell-specific	secretory granule lumen	Cellular component	-
ETS1	2113	v-ets avian erythroblastosis virus E26 oncogene homolog 1	negative regulation of cell cycle	Biological process	7753825
HP	3240	haptoglobin	response to hydrogen peroxide	Biological process	19740759
PTEN	5728	phosphatase and tensin homolog	plasma membrane	Cellular component	10760291
FBXO2	26232	F-box protein 2	negative regulation of cell proliferation	Biological process	-
ADM	133	adrenomedullin	heart development	Biological process	-
HTR1D	3352	5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled	vasoconstriction	Biological process	-
MYL2	4633	myosin, light chain 2, regulatory, cardiac, slow	myosin complex	Cellular component	11102452
FBLIM1	54751	filamin binding LIM protein 1	focal adhesion	Cellular component	21423176
HIST1H3F	8968	histone cluster 1, H3f	chromatin silencing at rDNA	Biological process	-
KDR	3791	kinase insert domain receptor	nucleus	Cellular component	-
RAB11FIP3	9727	RAB11 family interacting protein 3 (class II)	intracellular membrane-bounded organelle	Cellular component	-
TRIM72	493829	tripartite motif containing 72, E3 ubiquitin protein ligase	sarcolemma	Cellular component	-
CDCA3	83461	cell division cycle associated 3	protein ubiquitination	Biological process	-
CPNE1	8904	copine I	regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	14674885
TAB2	23118	TGF-beta activated kinase 1/MAP3K7 binding protein 2	Fc-epsilon receptor signaling pathway	Biological process	-
LAMA4	3910	laminin, alpha 4	regulation of cell adhesion	Biological process	-
ZNF861P	100302737	zinc finger protein 861, pseudogene	nucleic acid binding	Molecular function	-
SORL1	6653	sortilin-related receptor, L(DLR class) A repeats containing	positive regulation of protein localization to early endosome	Biological process	22621900
CMSS1	84319	cms1 ribosomal small subunit homolog (yeast)	poly(A) RNA binding	Molecular function	22658674
PEG3	5178	paternally expressed 3	cytoplasm	Cellular component	-
SLC11A1	6556	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1	iron ion transport	Biological process	16510578
ACOX1	51	acyl-CoA oxidase 1, palmitoyl	lipid homeostasis	Biological process	20195242
NUAK1	9891	NUAK family, SNF1-like kinase, 1	protein binding	Molecular function	19927127
TP53INP2	58476	tumor protein p53 inducible nuclear protein 2	autophagosome assembly	Biological process	19056683
AKAP13	11214	A kinase (PRKA) anchor protein 13	Rho guanyl-nucleotide exchange factor activity	Molecular function	-
WIF1	11197	WNT inhibitory factor 1	extracellular region	Cellular component	-
RAB1B	81876	RAB1B, member RAS oncogene family	autophagy	Biological process	-
NUBP1	4682	nucleotide binding protein 1	cytoplasm	Cellular component	-
EMP2	2013	epithelial membrane protein 2	protein localization to cell surface	Biological process	16216233
TXNDC12	51060	thioredoxin domain containing 12 (endoplasmic reticulum)	protein binding	Molecular function	25416956
KCNAB1	7881	potassium channel, voltage gated subfamily A regulatory beta subunit 1	NADPH binding	Molecular function	17540341
GOLPH3	64083	golgi phosphoprotein 3 (coat-protein)	gene expression	Biological process	23500462
CPB2	1361	carboxypeptidase B2 (plasma)	metallocarboxypeptidase activity	Molecular function	-
KIF5C	3800	kinesin family member 5C	protein binding	Molecular function	15644324
HDAC7	51564	histone deacetylase 7	protein binding	Molecular function	15161933
KDR	3791	kinase insert domain receptor	signal transduction by protein phosphorylation	Biological process	10022831
ITSN2	50618	intersectin 2	protein binding	Molecular function	17696407
CHMP3	51652	charged multivesicular body protein 3	endosomal transport	Biological process	-
SEC23IP	11196	SEC23 interacting protein	perinuclear endoplasmic reticulum	Cellular component	-
ITGA3	3675	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	regulation of Wnt signaling pathway	Biological process	24621570
SYNE1	23345	spectrin repeat containing, nuclear envelope 1	nucleus organization	Biological process	11792814
ADCK4	79934	aarF domain containing kinase 4	protein phosphorylation	Biological process	-
KANK1	23189	KN motif and ankyrin repeat domains 1	negative regulation of lamellipodium morphogenesis	Biological process	19171758
RASGRP3	25780	RAS guanyl releasing protein 3 (calcium and DAG-regulated)	guanyl-nucleotide exchange factor complex	Cellular component	-
ISOC1	51015	isochorismatase domain containing 1	biological_process	Biological process	-
LILRB1	10859	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	external side of plasma membrane	Cellular component	15585844
FLT3	2322	fms-related tyrosine kinase 3	organ regeneration	Biological process	-
SH3KBP1	30011	SH3-domain kinase binding protein 1	synapse	Cellular component	-
TAF1L	138474	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like	lysine-acetylated histone binding	Molecular function	22464331
CTSG	1511	cathepsin G	immune response	Biological process	2569462
TOR1AIP2	163590	torsin A interacting protein 2	ATPase activator activity	Molecular function	23569223
AP2A1	160	adaptor-related protein complex 2, alpha 1 subunit	plasma membrane	Cellular component	-
IFT57	55081	intraflagellar transport 57	cilium	Cellular component	-
LRRC8C	84230	leucine rich repeat containing 8 family, member C	ion transport	Biological process	-
MAML1	9794	mastermind-like 1 (Drosophila)	gene expression	Biological process	-
ZNF599	148103	zinc finger protein 599	protein binding	Molecular function	25416956
DDX51	317781	DEAD (Asp-Glu-Ala-Asp) box polypeptide 51	ATP-dependent RNA helicase activity	Molecular function	-
QPCT	25797	glutaminyl-peptide cyclotransferase	glutaminyl-peptide cyclotransferase activity	Molecular function	21288892
PIAS3	10401	protein inhibitor of activated STAT, 3	protein sumoylation	Biological process	-
IL2RG	3561	interleukin 2 receptor, gamma	external side of plasma membrane	Cellular component	-
HAO1	54363	hydroxyacid oxidase (glycolate oxidase) 1	receptor binding	Molecular function	20178365
PRKCD	5580	protein kinase C, delta	interferon-gamma-mediated signaling pathway	Biological process	-
FAU	2197	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed	RNA binding	Molecular function	8395683
RPL37A	6168	ribosomal protein L37a	focal adhesion	Cellular component	21423176
UCP3	7352	uncoupling protein 3 (mitochondrial, proton carrier)	mitochondrial inner membrane	Cellular component	-
NCF1	653361	neutrophil cytosolic factor 1	SH3 domain binding	Molecular function	7938008
IL19	29949	interleukin 19	inflammatory response	Biological process	-
OMA1	115209	OMA1 zinc metallopeptidase	lipid metabolic process	Biological process	22433842
RFNG	5986	RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	cell differentiation	Biological process	-
DROSHA	29102	drosha, ribonuclease type III	production of siRNA involved in RNA interference	Biological process	-
EID2	163126	EP300 interacting inhibitor of differentiation 2	muscle organ development	Biological process	-
GJA5	2702	gap junction protein, alpha 5, 40kDa	regulation of AV node cell action potential	Biological process	22247482
ITGB6	3694	integrin, beta 6	integrin complex	Cellular component	-
PICK1	9463	protein interacting with PRKCA 1	DNA methylation involved in gamete generation	Biological process	12138111
PDZD2	23037	PDZ domain containing 2	extracellular region	Cellular component	12671685
C11orf31	280636	chromosome 11 open reading frame 31	selenium binding	Molecular function	-
MYOCD	93649	myocardin	cell growth involved in cardiac muscle cell development	Biological process	-
VPS28	51160	vacuolar protein sorting 28 homolog (S. cerevisiae)	positive regulation of protein catabolic process	Biological process	11916981
SMG7	9887	SMG7 nonsense mediated mRNA decay factor	protein binding	Molecular function	14636577
IL1B	3553	interleukin 1, beta	MAPK cascade	Biological process	21147091
TLR4	7099	toll-like receptor 4	I-kappaB kinase/NF-kappaB signaling	Biological process	-
WDR19	57728	WD repeat domain 19	organelle organization	Biological process	-
PGLYRP4	57115	peptidoglycan recognition protein 4	detection of bacterium	Biological process	11461926
MAPRE3	22924	microtubule-associated protein, RP/EB family, member 3	positive regulation of transcription, DNA-templated	Biological process	17310996
SMPD4	55627	sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)	Golgi membrane	Cellular component	-
HYAL2	8692	hyaluronoglucosaminidase 2	hematopoietic progenitor cell differentiation	Biological process	-
ABHD14A	25864	abhydrolase domain containing 14A	extracellular exosome	Cellular component	23376485
TLX2	3196	T-cell leukemia homeobox 2	transcription, DNA-templated	Biological process	-
UBC	7316	ubiquitin C	MyD88-independent toll-like receptor signaling pathway	Biological process	-
TAGAP	117289	T-cell activation RhoGTPase activating protein	regulation of small GTPase mediated signal transduction	Biological process	-
IL10RB	3588	interleukin 10 receptor, beta	plasma membrane	Cellular component	10954742
PUF60	22827	poly-U binding splicing factor 60KDa	mitochondrion	Cellular component	-
RPLP0	6175	ribosomal protein, large, P0	ribonucleoprotein complex	Cellular component	17289661
LILRB1	10859	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	negative regulation of tumor necrosis factor biosynthetic process	Biological process	18684926
WNT8B	7479	wingless-type MMTV integration site family, member 8B	response to estradiol	Biological process	11956596
MTM1	4534	myotubularin 1	I band	Cellular component	-
ANKLE2	23141	ankyrin repeat and LEM domain containing 2	regulation of catalytic activity	Biological process	22770216
ESR2	2100	estrogen receptor 2 (ER beta)	estrogen receptor activity	Molecular function	11181953
MPI	4351	mannose phosphate isomerase	post-translational protein modification	Biological process	-
ADH1C	126	alcohol dehydrogenase 1C (class I), gamma polypeptide	cytosol	Cellular component	-
SOCS3	9021	suppressor of cytokine signaling 3	type I interferon signaling pathway	Biological process	-
RSPO2	340419	R-spondin 2	embryonic forelimb morphogenesis	Biological process	-
MTM1	4534	myotubularin 1	phosphoprotein phosphatase activity	Molecular function	9537414
XPA	7507	xeroderma pigmentosum, complementation group A	protein homodimerization activity	Molecular function	8197175
RAB3GAP1	22930	RAB3 GTPase activating protein subunit 1 (catalytic)	regulation of calcium ion-dependent exocytosis of neurotransmitter	Biological process	-
METAP2	10988	methionyl aminopeptidase 2	cytoplasm	Cellular component	-
ARSA	410	arylsulfatase A	glycosphingolipid metabolic process	Biological process	-
BECN1	8678	beclin 1, autophagy related	pre-autophagosomal structure	Cellular component	-
ACE2	59272	angiotensin I converting enzyme 2	carboxypeptidase activity	Molecular function	10924499
PTPRS	5802	protein tyrosine phosphatase, receptor type, S	protein binding	Molecular function	16273344
NR1H4	9971	nuclear receptor subfamily 1, group H, member 4	sequence-specific DNA binding transcription factor activity	Molecular function	10334992
SERPINA9	327657	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9	negative regulation of endopeptidase activity	Biological process	-
OR4E1	26687	olfactory receptor, family 4, subfamily E, member 1 (gene/pseudogene)	plasma membrane	Cellular component	-
SERPINE1	5054	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	platelet alpha granule lumen	Cellular component	-
ZEB1	6935	zinc finger E-box binding homeobox 1	double-stranded DNA binding	Molecular function	-
MRPL40	64976	mitochondrial ribosomal protein L40	nucleolus	Cellular component	-
NOTCH2	4853	notch 2	placenta blood vessel development	Biological process	-
CYP51A1	1595	cytochrome P450, family 51, subfamily A, polypeptide 1	cholesterol biosynthetic process	Biological process	-
ENO3	2027	enolase 3 (beta, muscle)	phosphopyruvate hydratase activity	Molecular function	-
CHRNA9	55584	cholinergic receptor, nicotinic, alpha 9 (neuronal)	detection of mechanical stimulus involved in sensory perception of sound	Biological process	-
NEUROG1	4762	neurogenin 1	nervous system development	Biological process	8816493
CNNM3	26505	cyclin and CBS domain divalent metal cation transport mediator 3	ion transport	Biological process	-
SOX17	64321	SRY (sex determining region Y)-box 17	embryonic heart tube morphogenesis	Biological process	-
CASP3	836	caspase 3, apoptosis-related cysteine peptidase	peptidase activity	Molecular function	17167422
AEBP2	121536	AE binding protein 2	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	-
F5	2153	coagulation factor V (proaccelerin, labile factor)	platelet degranulation	Biological process	-
OR11H1	81061	olfactory receptor, family 11, subfamily H, member 1	plasma membrane	Cellular component	-
AGPAT3	56894	1-acylglycerol-3-phosphate O-acyltransferase 3	glycerophospholipid biosynthetic process	Biological process	-
KCNA3	3738	potassium channel, voltage gated shaker related subfamily A, member 3	potassium ion transmembrane transport	Biological process	-
OR10G7	390265	olfactory receptor, family 10, subfamily G, member 7	plasma membrane	Cellular component	-
TNFSF4	7292	tumor necrosis factor (ligand) superfamily, member 4	negative regulation of interleukin-17 production	Biological process	18501882
HIF1A	3091	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	histone acetyltransferase binding	Molecular function	15261140
CDC14A	8556	cell division cycle 14A	protein tyrosine/serine/threonine phosphatase activity	Molecular function	-
EDNRB	1910	endothelin receptor type B	membrane raft	Cellular component	-
STK25	10494	serine/threonine kinase 25	stress-activated protein kinase signaling cascade	Biological process	-
GTPBP10	85865	GTP-binding protein 10 (putative)	GTP binding	Molecular function	-
PHB	5245	prohibitin	negative regulation of glucocorticoid receptor signaling pathway	Biological process	16964284
POSTN	10631	periostin, osteoblast specific factor	cell adhesion molecule binding	Molecular function	-
COX7A2L	9167	cytochrome c oxidase subunit VIIa polypeptide 2 like	cytochrome-c oxidase activity	Molecular function	-
DQX1	165545	DEAQ box RNA-dependent ATPase 1	ATP-dependent RNA helicase activity	Molecular function	-
DSTN	11034	destrin (actin depolymerizing factor)	actin polymerization or depolymerization	Biological process	8399167
GLIPR1L2	144321	GLI pathogenesis-related 1 like 2	integral component of membrane	Cellular component	-
ENO2	2026	enolase 2 (gamma, neuronal)	cytosol	Cellular component	-
METTL3	56339	methyltransferase like 3	RNA binding	Molecular function	-
STAR	6770	steroidogenic acute regulatory protein	cellular response to interferon-alpha	Biological process	-
DNAJC30	84277	DnaJ (Hsp40) homolog, subfamily C, member 30	mitochondrion	Cellular component	-
USP8	9101	ubiquitin specific peptidase 8	cell proliferation	Biological process	9628861
PRKRIP1	79706	PRKR interacting protein 1 (IL11 inducible)	negative regulation of protein kinase activity	Biological process	-
IRF2BPL	64207	interferon regulatory factor 2 binding protein-like	negative regulation of transcription from RNA polymerase II promoter	Biological process	17627301
PRKDC	5591	protein kinase, DNA-activated, catalytic polypeptide	cellular protein modification process	Biological process	7671312
RPL18	6141	ribosomal protein L18	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Biological process	-
HES5	388585	hes family bHLH transcription factor 5	regulation of cell differentiation	Biological process	-
PDIA4	9601	protein disulfide isomerase family A, member 4	cell redox homeostasis	Biological process	-
SHC2	25759	SHC (Src homology 2 domain containing) transforming protein 2	Ras protein signal transduction	Biological process	-
TMEM55B	90809	transmembrane protein 55B	metabolic process	Biological process	-
PKDCC	91461	protein kinase domain containing, cytoplasmic	protein kinase activity	Molecular function	-
CSF1R	1436	colony stimulating factor 1 receptor	monocyte differentiation	Biological process	19132917
IFNA8	3445	interferon, alpha 8	positive regulation of peptidyl-serine phosphorylation of STAT protein	Biological process	-
KIT	3815	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	melanocyte differentiation	Biological process	21057534
MOB1B	92597	MOB kinase activator 1B	protein binding	Molecular function	19739119
DCTN1	1639	dynactin 1	IRE1-mediated unfolded protein response	Biological process	-
RHOC	389	ras homolog family member C	nucleus	Cellular component	-
SYTL4	94121	synaptotagmin-like 4	extrinsic component of membrane	Cellular component	-
REG3A	5068	regenerating islet-derived 3 alpha	negative regulation of keratinocyte differentiation	Biological process	-
KCNC1	3746	potassium channel, voltage gated Shaw related subfamily C, member 1	protein homooligomerization	Biological process	-
WNT3A	89780	wingless-type MMTV integration site family, member 3A	positive regulation of canonical Wnt signaling pathway	Biological process	-
SEC24D	9871	SEC24 family member D	membrane organization	Biological process	-
NCSTN	23385	nicastrin	myeloid cell homeostasis	Biological process	-
ANKRD17	26057	ankyrin repeat domain 17	positive regulation of MDA-5 signaling pathway	Biological process	22328336
WNT2B	7482	wingless-type MMTV integration site family, member 2B	iris morphogenesis	Biological process	16258938
PSKH2	85481	protein serine kinase H2	ATP binding	Molecular function	-
BTK	695	Bruton agammaglobulinemia tyrosine kinase	regulation of cell proliferation	Biological process	-
SEL1L	6400	sel-1 suppressor of lin-12-like (C. elegans)	ER-associated ubiquitin-dependent protein catabolic process	Biological process	22013210
GATA3	2625	GATA binding protein 3	ureter maturation	Biological process	-
S100P	6286	S100 calcium binding protein P	response to organic substance	Biological process	17486081
CEP72	55722	centrosomal protein 72kDa	protein binding	Molecular function	19536135
INHBA	3624	inhibin, beta A	identical protein binding	Molecular function	2575216
ITGA8	8516	integrin, alpha 8	cell-matrix adhesion	Biological process	7768999
RAB41	347517	RAB41, member RAS oncogene family	Rab protein signal transduction	Biological process	-
GSTT1	2952	glutathione S-transferase theta 1	glutathione metabolic process	Biological process	20097269
P2RY6	5031	pyrimidinergic receptor P2Y, G-protein coupled, 6	transepithelial chloride transport	Biological process	-
HCLS1	3059	hematopoietic cell-specific Lyn substrate 1	protein binding	Molecular function	16189514
DRG1	4733	developmentally regulated GTP binding protein 1	transcription factor binding	Molecular function	9824680
BIRC3	330	baculoviral IAP repeat containing 3	regulation of necroptotic process	Biological process	21737330
ANO7	50636	anoctamin 7	ion transmembrane transport	Biological process	-
CCZ1	51622	CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)	vesicle-mediated transport	Biological process	-
KDM1A	23028	lysine (K)-specific demethylase 1A	enzyme binding	Molecular function	17277772
MIP	4284	major intrinsic protein of lens fiber	glycerol transport	Biological process	-
EXOSC10	5394	exosome component 10	nucleoplasm	Cellular component	-
PTGS2	5743	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	cytoplasm	Cellular component	-
MRC2	9902	mannose receptor, C type 2	carbohydrate binding	Molecular function	-
SMAD4	4089	SMAD family member 4	protein binding	Molecular function	11278302
PAFAH1B2	5049	platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)	extracellular exosome	Cellular component	19056867
RTCB	51493	RNA 2',3'-cyclic phosphate and 5'-OH ligase	placenta development	Biological process	-
SLC17A7	57030	solute carrier family 17 (vesicular glutamate transporter), member 7	inorganic phosphate transmembrane transporter activity	Molecular function	-
CAMK2B	816	calcium/calmodulin-dependent protein kinase II beta	cytokine-mediated signaling pathway	Biological process	-
ESR2	2100	estrogen receptor 2 (ER beta)	regulation of transcription, DNA-templated	Biological process	11181953
SLIRP	81892	SRA stem-loop interacting RNA binding protein	nucleus	Cellular component	-
ID2	3398	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	circadian regulation of gene expression	Biological process	-
AGAP4	119016	ArfGAP with GTPase domain, ankyrin repeat and PH domain 4	GTPase activator activity	Molecular function	-
ST6GAL2	84620	ST6 beta-galactosamide alpha-2,6-sialyltranferase 2	multicellular organismal development	Biological process	12235148
SOD2	6648	superoxide dismutase 2, mitochondrial	release of cytochrome c from mitochondria	Biological process	-
SCARB2	950	scavenger receptor class B, member 2	receptor activity	Molecular function	-
GCN1L1	10985	GCN1 general control of amino-acid synthesis 1-like 1 (yeast)	poly(A) RNA binding	Molecular function	22681889
APOE	348	apolipoprotein E	microtubule	Cellular component	-
MYNN	55892	myoneurin	transcription, DNA-templated	Biological process	-
MSX1	4487	msh homeobox 1	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
SENP2	59343	SUMO1/sentrin/SMT3 specific peptidase 2	dorsal/ventral axis specification	Biological process	-
PRAMEF25	441873	PRAME family member 25	retinoic acid receptor binding	Molecular function	-
AKR7A2	8574	aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)	oxidation-reduction process	Biological process	-
ADCY2	108	adenylate cyclase 2 (brain)	cAMP biosynthetic process	Biological process	-
RPS10	6204	ribosomal protein S10	translational initiation	Biological process	-
PILRA	29992	paired immunoglobin-like type 2 receptor alpha	extracellular exosome	Cellular component	20458337
DDX41	51428	DEAD (Asp-Glu-Ala-Asp) box polypeptide 41	defense response to virus	Biological process	-
CD74	972	CD74 molecule, major histocompatibility complex, class II invariant chain	cytokine receptor activity	Molecular function	17045821
COL5A1	1289	collagen, type V, alpha 1	collagen biosynthetic process	Biological process	11278977
FGD2	221472	FYVE, RhoGEF and PH domain containing 2	positive regulation of GTPase activity	Biological process	-
RBM20	282996	RNA binding motif protein 20	heart development	Biological process	22466703
G3BP1	10146	GTPase activating protein (SH3 domain) binding protein 1	plasma membrane	Cellular component	-
DIP2A	23181	DIP2 disco-interacting protein 2 homolog A (Drosophila)	catalytic activity	Molecular function	-
SLC9A3	6550	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3	PDZ domain binding	Molecular function	-
RPA2	6118	replication protein A2, 32kDa	ubiquitin protein ligase binding	Molecular function	21504906
OLFML2A	169611	olfactomedin-like 2A	extracellular matrix binding	Molecular function	-
POU2F1	5451	POU class 2 homeobox 1	transcription from RNA polymerase III promoter	Biological process	-
RPLP0	6175	ribosomal protein, large, P0	cytosol	Cellular component	-
LPAR2	9170	lysophosphatidic acid receptor 2	plasma membrane	Cellular component	-
YWHAB	7529	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta	protein binding	Molecular function	10713667
KLK6	5653	kallikrein-related peptidase 6	protein binding	Molecular function	12709365
GRM7	2917	glutamate receptor, metabotropic 7	calcium ion binding	Molecular function	18599484
SACS	26278	sacsin molecular chaperone	cytoplasm	Cellular component	19208651
BCL2L11	10018	BCL2-like 11 (apoptosis facilitator)	apoptotic process	Biological process	10381623
ADNP2	22850	ADNP homeobox 2	positive regulation of cell growth	Biological process	-
SNAP91	9892	synaptosomal-associated protein, 91kDa	plasma membrane	Cellular component	-
TOR1B	27348	torsin family 1, member B (torsin B)	endoplasmic reticulum lumen	Cellular component	20015956
NCSTN	23385	nicastrin	extracellular matrix disassembly	Biological process	-
TMEM173	340061	transmembrane protein 173	positive regulation of transcription factor import into nucleus	Biological process	18818105
MTX2	10651	metaxin 2	mitochondrial outer membrane	Cellular component	-
LIMK1	3984	LIM domain kinase 1	positive regulation of stress fiber assembly	Biological process	-
SLC35C2	51006	solute carrier family 35 (GDP-fucose transporter), member C2	integral component of membrane	Cellular component	-
DIAPH2	1730	diaphanous-related formin 2	cytosol	Cellular component	-
PHOX2B	8929	paired-like homeobox 2b	enteric nervous system development	Biological process	12640453
HACE1	57531	HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1	Rab GTPase binding	Molecular function	21988917
RNF126	55658	ring finger protein 126	cytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process	Biological process	24981174
GTF3C3	9330	general transcription factor IIIC, polypeptide 3, 102kDa	tRNA transcription from RNA polymerase III promoter	Biological process	17409385
UTRN	7402	utrophin	membrane	Cellular component	1426262
XKRY	9082	XK, Kell blood group complex subunit-related, Y-linked	single fertilization	Biological process	9381176
PI4KA	5297	phosphatidylinositol 4-kinase, catalytic, alpha	phospholipid metabolic process	Biological process	-
SUCLG1	8802	succinate-CoA ligase, alpha subunit	cofactor binding	Molecular function	-
KIF2A	3796	kinesin heavy chain member 2A	kinesin complex	Cellular component	-
MGAT4A	11320	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A	post-translational protein modification	Biological process	-
ACSM2B	348158	acyl-CoA synthetase medium-chain family member 2B	butyrate-CoA ligase activity	Molecular function	-
DCX	1641	doublecortin	calcium-dependent protein serine/threonine kinase activity	Molecular function	-
IFNGR1	3459	interferon gamma receptor 1	interferon-gamma-mediated signaling pathway	Biological process	-
CCNL1	57018	cyclin L1	protein binding	Molecular function	25416956
XIRP2	129446	xin actin-binding repeat containing 2	cardiac muscle tissue morphogenesis	Biological process	-
TP53	7157	tumor protein p53	nucleolus	Cellular component	12080348
SUB1	10923	SUB1 homolog (S. cerevisiae)	single-stranded DNA binding	Molecular function	8062391
UBE2Z	65264	ubiquitin-conjugating enzyme E2Z	nucleoplasm	Cellular component	-
CD80	941	CD80 molecule	coreceptor activity	Molecular function	9915850
TGIF2	60436	TGFB-induced factor homeobox 2	retina development in camera-type eye	Biological process	-
KCNA1	3736	potassium channel, voltage gated shaker related subfamily A, member 1	regulation of muscle contraction	Biological process	-
UGT1A8	54576	UDP glucuronosyltransferase 1 family, polypeptide A8	fatty acid binding	Molecular function	19996319
NEUROD1	4760	neuronal differentiation 1	RNA polymerase II transcription factor complex	Cellular component	10545951
LYN	4067	LYN proto-oncogene, Src family tyrosine kinase	regulation of mast cell activation	Biological process	-
GNB2L1	10399	guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1	cellular response to glucose stimulus	Biological process	20103773
GSK3A	2931	glycogen synthase kinase 3 alpha	protein kinase A catalytic subunit binding	Molecular function	11035810
AK4	205	adenylate kinase 4	brain development	Biological process	-
UBE2B	7320	ubiquitin-conjugating enzyme E2B	nucleoplasm	Cellular component	-
TNIP3	79931	TNFAIP3 interacting protein 3	negative regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	17088249
UBR5	51366	ubiquitin protein ligase E3 component n-recognin 5	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	-
BMP4	652	bone morphogenetic protein 4	osteoblast differentiation	Biological process	17720811
HEY2	23493	hes-related family bHLH transcription factor with YRPW motif 2	regulation of auditory receptor cell differentiation	Biological process	-
POR	5447	P450 (cytochrome) oxidoreductase	internal peptidyl-lysine acetylation	Biological process	-
DMRT1	1761	doublesex and mab-3 related transcription factor 1	negative regulation of meiotic nuclear division	Biological process	-
C19orf12	83636	chromosome 19 open reading frame 12	mitochondrial membrane	Cellular component	-
HEYL	26508	hes-related family bHLH transcription factor with YRPW motif-like	skeletal muscle cell differentiation	Biological process	-
OGDH	4967	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)	2-oxoglutarate metabolic process	Biological process	-
MSH2	4436	mutS homolog 2	oxidized purine DNA binding	Molecular function	11756455
IL10	3586	interleukin 10	response to drug	Biological process	-
FLT3	2322	fms-related tyrosine kinase 3	transmembrane receptor protein tyrosine kinase activity	Molecular function	19549778
RPL8	6132	ribosomal protein L8	translational termination	Biological process	-
OXTR	5021	oxytocin receptor	telencephalon development	Biological process	-
GOSR1	9527	golgi SNAP receptor complex member 1	membrane fusion	Biological process	15215310
TAX1BP3	30851	Tax1 (human T-cell leukemia virus type I) binding protein 3	actin cytoskeleton	Cellular component	-
CHSY1	22856	chondroitin sulfate synthase 1	carbohydrate metabolic process	Biological process	-
RAPGEF1	2889	Rap guanine nucleotide exchange factor (GEF) 1	establishment of endothelial barrier	Biological process	21840392
PHYKPL	85007	5-phosphohydroxy-L-lysine phospho-lyase	transaminase activity	Molecular function	-
INHBA	3624	inhibin, beta A	ovarian follicle development	Biological process	9166111
MMS19	64210	MMS19 nucleotide excision repair homolog (S. cerevisiae)	chromosome segregation	Biological process	20797633
PAIP2B	400961	poly(A) binding protein interacting protein 2B	cytoplasm	Cellular component	16804161
POU3F2	5454	POU class 3 homeobox 2	regulation of axonogenesis	Biological process	-
GHRHR	2692	growth hormone releasing hormone receptor	regulation of intracellular steroid hormone receptor signaling pathway	Biological process	-
UBR4	23352	ubiquitin protein ligase E3 component n-recognin 4	ubiquitin-protein transferase activity	Molecular function	23932781
IRF3	3661	interferon regulatory factor 3	cytokine-mediated signaling pathway	Biological process	-
CFHR4	10877	complement factor H-related 4	extracellular region	Cellular component	-
CHCHD1	118487	coiled-coil-helix-coiled-coil-helix domain containing 1	protein binding	Molecular function	22190034
ROBO1	6091	roundabout, axon guidance receptor, homolog 1 (Drosophila)	identical protein binding	Molecular function	12504588
NDFIP2	54602	Nedd4 family interacting protein 2	intracellular membrane-bounded organelle	Cellular component	-
C1QBP	708	complement component 1, q subcomponent binding protein	protein binding	Molecular function	10831594
CHMP4C	92421	charged multivesicular body protein 4C	regulation of mitotic spindle assembly	Biological process	20616062
ABCD1	215	ATP-binding cassette, sub-family D (ALD), member 1	cellular lipid metabolic process	Biological process	-
TTI2	80185	TELO2 interacting protein 2	cytoplasm	Cellular component	-
ELMO3	79767	engulfment and cell motility 3	apoptotic process	Biological process	-
TRIM8	81603	tripartite motif containing 8	negative regulation of viral transcription	Biological process	-
HYAL2	8692	hyaluronoglucosaminidase 2	RNA polymerase II transcription factor complex	Cellular component	19366691
DSP	1832	desmoplakin	cornified envelope	Cellular component	10908733
HSPA1L	3305	heat shock 70kDa protein 1-like	positive regulation of protein targeting to mitochondrion	Biological process	24270810
ARRB1	408	arrestin, beta 1	membrane organization	Biological process	-
NPY2R	4887	neuropeptide Y receptor Y2	neuropeptide Y receptor activity	Molecular function	7559383
MEN1	4221	multiple endocrine neoplasia I	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	-
SLC39A12	221074	solute carrier family 39 (zinc transporter), member 12	regulation of microtubule polymerization	Biological process	-
STK33	65975	serine/threonine kinase 33	perinuclear region of cytoplasm	Cellular component	-
PDE3A	5139	phosphodiesterase 3A, cGMP-inhibited	blood coagulation	Biological process	-
BRD4	23476	bromodomain containing 4	chromosome	Cellular component	23728299
ASS1	445	argininosuccinate synthase 1	cytoplasm	Cellular component	6194510
LUC7L2	51631	LUC7-like 2 (S. cerevisiae)	nuclear speck	Cellular component	-
SMOX	54498	spermine oxidase	spermine catabolic process	Biological process	-
HES1	3280	hes family bHLH transcription factor 1	S-shaped body morphogenesis	Biological process	-
ITCH	83737	itchy E3 ubiquitin protein ligase	cytosol	Cellular component	-
EXT1	2131	exostosin glycosyltransferase 1	embryonic skeletal joint development	Biological process	-
KCNH3	23416	potassium channel, voltage gated eag related subfamily H, member 3	voltage-gated potassium channel activity	Molecular function	10455180
AKAP14	158798	A kinase (PRKA) anchor protein 14	cytoplasm	Cellular component	-
TTYH1	57348	tweety family member 1	integral component of membrane	Cellular component	10950931
PINK1	65018	PTEN induced putative kinase 1	ubiquitin protein ligase binding	Molecular function	20798600
LCLAT1	253558	lysocardiolipin acyltransferase 1	integral component of membrane	Cellular component	-
SIRPG	55423	signal-regulatory protein gamma	cell adhesion	Biological process	-
STT3A	3703	STT3A, subunit of the oligosaccharyltransferase complex (catalytic)	dolichyl-diphosphooligosaccharide-protein glycotransferase activity	Molecular function	-
COG2	22796	component of oligomeric golgi complex 2	Golgi transport complex	Cellular component	7962052
RELA	5970	v-rel avian reticuloendotheliosis viral oncogene homolog A	negative regulation of NIK/NF-kappaB signaling	Biological process	18212740
UCN2	90226	urocortin 2	negative regulation of luteinizing hormone secretion	Biological process	-
TP63	8626	tumor protein p63	post-anal tail morphogenesis	Biological process	-
EML1	2009	echinoderm microtubule associated protein like 1	mitotic spindle midzone	Cellular component	-
MAS1	4142	MAS1 proto-oncogene, G protein-coupled receptor	response to gonadotropin	Biological process	-
MTRNR2L4	100463285	MT-RNR2-like 4	extracellular region	Cellular component	-
DHX29	54505	DEAH (Asp-Glu-Ala-His) box polypeptide 29	mitochondrion	Cellular component	-
SLC4A8	9498	solute carrier family 4, sodium bicarbonate cotransporter, member 8	plasma membrane	Cellular component	-
SPINK1	6690	serine peptidase inhibitor, Kazal type 1	negative regulation of peptidyl-tyrosine phosphorylation	Biological process	-
EXD3	54932	exonuclease 3'-5' domain containing 3	nucleic acid binding	Molecular function	-
POLR3H	171568	polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)	positive regulation of type I interferon production	Biological process	-
CST7	8530	cystatin F (leukocystatin)	extracellular region	Cellular component	-
KIF28P	100130097	kinesin family member 28, pseudogene	kinesin complex	Cellular component	-
CDH2	1000	cadherin 2, type 1, N-cadherin (neuronal)	integral component of membrane	Cellular component	-
TELO2	9894	telomere maintenance 2	TORC1 complex	Cellular component	23263282
ABI2	10152	abl-interactor 2	cytosol	Cellular component	17101133
GATA6	2627	GATA binding protein 6	transcription factor binding	Molecular function	14988427
RASA1	5921	RAS p21 protein activator (GTPase activating protein) 1	blood vessel morphogenesis	Biological process	23687085
RHO	6010	rhodopsin	visual perception	Biological process	-
PPP3CC	5533	protein phosphatase 3, catalytic subunit, gamma isozyme	metal ion binding	Molecular function	-
TNNC1	7134	troponin C type 1 (slow)	diaphragm contraction	Biological process	-
C4BPB	725	complement component 4 binding protein, beta	plasma membrane	Cellular component	-
HIST1H1T	3010	histone cluster 1, H1t	sperm motility	Biological process	-
TBCC	6903	tubulin folding cofactor C	protein folding	Biological process	8706133
PPARD	5467	peroxisome proliferator-activated receptor delta	intracellular receptor signaling pathway	Biological process	-
EDN1	1906	endothelin 1	nitric oxide transport	Biological process	16820593
COG3	83548	component of oligomeric golgi complex 3	intra-Golgi vesicle-mediated transport	Biological process	11929878
FBLN1	2192	fibulin 1	extracellular matrix structural constituent	Molecular function	2269669
PDGFRB	5159	platelet-derived growth factor receptor, beta polypeptide	positive regulation of phosphoprotein phosphatase activity	Biological process	7691811
FAM96B	51647	family with sequence similarity 96, member B	nucleoplasm	Cellular component	-
MED31	51003	mediator complex subunit 31	gene expression	Biological process	-
BOK	666	BCL2-related ovarian killer	integral component of membrane	Cellular component	-
SLC35D2	11046	solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2	Golgi membrane	Cellular component	-
ELMO2	63916	engulfment and cell motility 2	SH3 domain binding	Molecular function	-
RRP1	8568	ribosomal RNA processing 1	nucleus	Cellular component	9192856
FAT1	2195	FAT atypical cadherin 1	cell migration	Biological process	-
MUC6	4588	mucin 6, oligomeric mucus/gel-forming	maintenance of gastrointestinal epithelium	Biological process	7680650
NR2E1	7101	nuclear receptor subfamily 2, group E, member 1	somatic stem cell maintenance	Biological process	-
TOR1A	1861	torsin family 1, member A (torsin A)	nuclear envelope organization	Biological process	-
MYOF	26509	myoferlin	phospholipid binding	Molecular function	-
PRKCA	5578	protein kinase C, alpha	protein binding	Molecular function	12571249
ANXA1	301	annexin A1	prostate gland development	Biological process	-
VPS16	64601	vacuolar protein sorting 16 homolog (S. cerevisiae)	vacuole organization	Biological process	-
TP53INP2	58476	tumor protein p53 inducible nuclear protein 2	positive regulation of transcription, DNA-templated	Biological process	22470510
S100A8	6279	S100 calcium binding protein A8	protein binding	Molecular function	20936779
AR	367	androgen receptor	negative regulation of extrinsic apoptotic signaling pathway	Biological process	21310825
C1orf174	339448	chromosome 1 open reading frame 174	nucleus	Cellular component	-
OVOS	408186	ovostatin	serine-type endopeptidase inhibitor activity	Molecular function	-
AARS	16	alanyl-tRNA synthetase	protein folding	Biological process	-
PPP2R1A	5518	protein phosphatase 2, regulatory subunit A, alpha	regulation of growth	Biological process	11360189
IGFBP5	3488	insulin-like growth factor binding protein 5	negative regulation of translation	Biological process	15700281
GALM	130589	galactose mutarotase (aldose 1-epimerase)	glucose metabolic process	Biological process	12753898
NR4A1	3164	nuclear receptor subfamily 4, group A, member 1	intracellular receptor signaling pathway	Biological process	2626032
PSMB11	122706	proteasome (prosome, macropain) subunit, beta type, 11	protein polyubiquitination	Biological process	-
STX10	8677	syntaxin 10	syntaxin binding	Molecular function	16154903
GNGT1	2792	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	metabolic process	Biological process	8661128
TRAF5	7188	TNF receptor-associated factor 5	ubiquitin protein ligase binding	Molecular function	11279055
ULBP3	79465	UL16 binding protein 3	natural killer cell mediated cytotoxicity	Biological process	11239445
PRB3	5544	proline-rich protein BstNI subfamily 3	extracellular region	Cellular component	1894623
LHX3	8022	LIM homeobox 3	transcription from RNA polymerase II promoter	Biological process	-
RIN1	9610	Ras and Rab interactor 1	cytoplasm	Cellular component	12574403
HSPA8	3312	heat shock 70kDa protein 8	ATP binding	Molecular function	23921388
BMPR1A	657	bone morphogenetic protein receptor, type IA	hindlimb morphogenesis	Biological process	-
MTF2	22823	metal response element binding transcription factor 2	zinc ion binding	Molecular function	-
COL4A1	1282	collagen, type IV, alpha 1	extracellular matrix	Cellular component	22261194
AGO4	192670	argonaute RISC catalytic component 4	Notch signaling pathway	Biological process	-
ENPP1	5167	ectonucleotide pyrophosphatase/phosphodiesterase 1	cell surface	Cellular component	10513816
CD276	80381	CD276 molecule	integral component of membrane	Cellular component	15188059
SERPINB3	6317	serpin peptidase inhibitor, clade B (ovalbumin), member 3	negative regulation of peptidase activity	Biological process	12949073
PTK2B	2185	protein tyrosine kinase 2 beta	response to immobilization stress	Biological process	-
COPE	11316	coatomer protein complex, subunit epsilon	ER to Golgi vesicle-mediated transport	Biological process	-
NEK6	10783	NIMA-related kinase 6	microtubule organizing center	Cellular component	-
EGF	1950	epidermal growth factor	positive regulation of hyaluronan biosynthetic process	Biological process	17324121
RARA	5914	retinoic acid receptor, alpha	positive regulation of phosphatidylinositol 3-kinase signaling	Biological process	-
ADAM17	6868	ADAM metallopeptidase domain 17	positive regulation of chemokine production	Biological process	16034137
LIPT2	387787	lipoyl(octanoyl) transferase 2 (putative)	ligase activity	Molecular function	-
RPS6KB2	6199	ribosomal protein S6 kinase, 70kDa, polypeptide 2	fibroblast growth factor receptor signaling pathway	Biological process	-
KNG1	3827	kininogen 1	positive regulation of renal sodium excretion	Biological process	11385996
EIF4H	7458	eukaryotic translation initiation factor 4H	membrane	Cellular component	19946888
MAPK8IP2	23542	mitogen-activated protein kinase 8 interacting protein 2	neuronal postsynaptic density	Cellular component	-
NEUROG3	50674	neurogenin 3	spinal cord development	Biological process	-
SNRPG	6637	small nuclear ribonucleoprotein polypeptide G	termination of RNA polymerase II transcription	Biological process	-
HVCN1	84329	hydrogen voltage gated channel 1	response to pH	Biological process	16556803
OXR1	55074	oxidation resistance 1	adult walking behavior	Biological process	-
EIF2S3	1968	eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa	GTP binding	Molecular function	-
BASP1	10409	brain abundant, membrane attached signal protein 1	nuclear speck	Cellular component	-
SERINC5	256987	serine incorporator 5	phosphatidylserine metabolic process	Biological process	-
CRYAB	1410	crystallin, alpha B	stress-activated MAPK cascade	Biological process	-
ADCYAP1R1	117	adenylate cyclase activating polypeptide 1 (pituitary) receptor type I	response to ethanol	Biological process	-
RBFOX1	54715	RNA binding protein, fox-1 homolog (C. elegans) 1	RNA binding	Molecular function	10814712
DIAPH1	1729	diaphanous-related formin 1	regulation of release of sequestered calcium ion into cytosol	Biological process	15123714
HIST4H4	121504	histone cluster 4, H4	nucleoplasm	Cellular component	-
SUPT3H	8464	suppressor of Ty 3 homolog (S. cerevisiae)	chromatin organization	Biological process	-
NDUFS2	4720	NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)	electron carrier activity	Molecular function	9647766
DRD3	1814	dopamine receptor D3	plasma membrane	Cellular component	-
EPS15	2060	epidermal growth factor receptor pathway substrate 15	vesicle organization	Biological process	9762922
RAB8A	4218	RAB8A, member RAS oncogene family	synaptic vesicle exocytosis	Biological process	-
CYP26A1	1592	cytochrome P450, family 26, subfamily A, polypeptide 1	retinoic acid 4-hydroxylase activity	Molecular function	10823918
CACNA1D	776	calcium channel, voltage-dependent, L type, alpha 1D subunit	voltage-gated calcium channel activity involved in cardiac muscle cell action potential	Molecular function	21859974
TNIK	23043	TRAF2 and NCK interacting kinase	cytoskeleton	Cellular component	15342639
GDF9	2661	growth differentiation factor 9	oocyte growth	Biological process	-
UBE2G1	7326	ubiquitin-conjugating enzyme E2G 1	ubiquitin-dependent protein catabolic process	Biological process	8893823
PSMC5	5705	proteasome (prosome, macropain) 26S subunit, ATPase, 5	cellular nitrogen compound metabolic process	Biological process	-
PRTN3	5657	proteinase 3	blood coagulation	Biological process	-
SLC10A5	347051	solute carrier family 10, member 5	transmembrane transport	Biological process	-
ZNF829	374899	zinc finger protein 829	DNA binding	Molecular function	-
NRG1	3084	neuregulin 1	endocardial cell differentiation	Biological process	17336907
F3	2152	coagulation factor III (thromboplastin, tissue factor)	cell surface	Cellular component	17898544
ABLIM2	84448	actin binding LIM protein family, member 2	myofibril	Cellular component	-
VAPA	9218	VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa	endoplasmic reticulum exit site	Cellular component	18713837
TOLLIP	54472	toll interacting protein	autophagy	Biological process	-
ATP5S	27109	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)	proton transport	Biological process	6143319
CLCN3	1182	chloride channel, voltage-sensitive 3	late endosome	Cellular component	12471024
S100A2	6273	S100 calcium binding protein A2	endothelial cell migration	Biological process	15313892
MAFF	23764	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F	regulation of epidermal cell differentiation	Biological process	-
ADAM17	6868	ADAM metallopeptidase domain 17	plasma membrane	Cellular component	-
OPRD1	4985	opioid receptor, delta 1	dendrite membrane	Cellular component	-
HHIP	64399	hedgehog interacting protein	negative regulation of signal transduction	Biological process	19561609
ZIC3	7547	Zic family member 3	determination of digestive tract left/right asymmetry	Biological process	9354794
SNX10	29887	sorting nexin 10	vesicle organization	Biological process	-
ANK2	287	ankyrin 2, neuronal	M band	Cellular component	-
MFN2	9927	mitofusin 2	integral component of membrane	Cellular component	-
USP19	10869	ubiquitin specific peptidase 19	ubiquitin-specific protease activity	Molecular function	19465887
OR51T1	401665	olfactory receptor, family 51, subfamily T, member 1	G-protein coupled receptor signaling pathway	Biological process	-
OR2M5	127059	olfactory receptor, family 2, subfamily M, member 5	G-protein coupled receptor activity	Molecular function	-
KIR3DL2	3812	killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2	cellular defense response	Biological process	7716543
TCTEX1D4	343521	Tctex1 domain containing 4	protein binding	Molecular function	21382349
NLGN1	22871	neuroligin 1	positive regulation of intracellular signal transduction	Biological process	-
CBLC	23624	Cbl proto-oncogene C, E3 ubiquitin protein ligase	SH3 domain binding	Molecular function	10362357
MDH1	4190	malate dehydrogenase 1, NAD (soluble)	carbohydrate metabolic process	Biological process	-
PIN4	5303	peptidylprolyl cis/trans isomerase, NIMA-interacting 4	poly(A) RNA binding	Molecular function	22681889
RC3H2	54542	ring finger and CCCH-type domains 2	T cell proliferation	Biological process	-
ABCA1	19	ATP-binding cassette, sub-family A (ABC1), member 1	response to nutrient	Biological process	-
REC8	9985	REC8 meiotic recombination protein	male germ cell nucleus	Cellular component	-
TPSB2	64499	tryptase beta 2 (gene/pseudogene)	serine-type peptidase activity	Molecular function	2203827
TRPM4	54795	transient receptor potential cation channel, subfamily M, member 4	ion transmembrane transport	Biological process	-
APOBEC3A	200315	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A	cytidine deamination	Biological process	20062055
OSGEP	55644	O-sialoglycoprotein endopeptidase	nucleus	Cellular component	-
NUBP1	4682	nucleotide binding protein 1	metal ion binding	Molecular function	-
PCSK5	5125	proprotein convertase subtilisin/kexin type 5	Golgi apparatus	Cellular component	-
PDGFRA	5156	platelet-derived growth factor receptor, alpha polypeptide	cardiac myofibril assembly	Biological process	-
DACT3	147906	dishevelled-binding antagonist of beta-catenin 3	cytoplasm	Cellular component	-
IL1RN	3557	interleukin 1 receptor antagonist	response to starvation	Biological process	-
OR7G1	125962	olfactory receptor, family 7, subfamily G, member 1	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
PITPNM2	57605	phosphatidylinositol transfer protein, membrane-associated 2	integral component of membrane	Cellular component	10022914
DLG1	1739	discs, large homolog 1 (Drosophila)	basolateral plasma membrane	Cellular component	8922391
PPP2CB	5516	protein phosphatase 2, catalytic subunit, beta isozyme	response to antibiotic	Biological process	-
AAAS	8086	achalasia, adrenocortical insufficiency, alacrimia	fertilization	Biological process	-
MYNN	55892	myoneurin	DNA binding	Molecular function	-
PC	5091	pyruvate carboxylase	biotin metabolic process	Biological process	-
TOB1	10140	transducer of ERBB2, 1	negative regulation of osteoblast differentiation	Biological process	-
BBS4	585	Bardet-Biedl syndrome 4	centriolar satellite	Cellular component	15107855
DDX39A	10212	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A	regulation of gene expression	Biological process	-
FSTL1	11167	follistatin-like 1	BMP signaling pathway	Biological process	-
CRHBP	1393	corticotropin releasing hormone binding protein	cellular response to drug	Biological process	-
UBQLN1	29979	ubiquilin 1	negative regulation of autophagosome fusion	Biological process	23459205
NUP85	79902	nucleoporin 85kDa	cellular response to heat	Biological process	-
SLC25A33	84275	solute carrier family 25 (pyrimidine nucleotide carrier), member 33	mitochondrial respiratory chain complex III assembly	Biological process	20453889
MRPS11	64963	mitochondrial ribosomal protein S11	DNA damage response, detection of DNA damage	Biological process	15300802
MAPK8IP1	9479	mitogen-activated protein kinase 8 interacting protein 1	JUN phosphorylation	Biological process	-
KITLG	4254	KIT ligand	plasma membrane	Cellular component	-
RPSA	3921	ribosomal protein SA	nucleus	Cellular component	16130169
PPA2	27068	pyrophosphatase (inorganic) 2	tRNA aminoacylation for protein translation	Biological process	-
RPL7	6129	ribosomal protein L7	nucleolus	Cellular component	16791210
CTCFL	140690	CCCTC-binding factor (zinc finger protein)-like	cytoplasm	Cellular component	-
MEGF9	1955	multiple EGF-like-domains 9	integral component of membrane	Cellular component	-
ECT2	1894	epithelial cell transforming 2	positive regulation of neuron differentiation	Biological process	-
ST3GAL2	6483	ST3 beta-galactoside alpha-2,3-sialyltransferase 2	O-glycan processing	Biological process	-
OPN1SW	611	opsin 1 (cone pigments), short-wave-sensitive	retinoid metabolic process	Biological process	-
RASSF10	644943	Ras association (RalGDS/AF-6) domain family (N-terminal) member 10	signal transduction	Biological process	-
HYAL2	8692	hyaluronoglucosaminidase 2	cellular response to tumor necrosis factor	Biological process	18390475
FAM156A	29057	family with sequence similarity 156, member A	integral component of membrane	Cellular component	-
CSK	1445	c-src tyrosine kinase	negative regulation of cell proliferation	Biological process	-
PPP2R5D	5528	protein phosphatase 2, regulatory subunit B', delta	stress-activated MAPK cascade	Biological process	-
HNF1B	6928	HNF1 homeobox B	anterior/posterior pattern specification	Biological process	-
OR5M9	390162	olfactory receptor, family 5, subfamily M, member 9	olfactory receptor activity	Molecular function	-
ARHGDIB	397	Rho GDP dissociation inhibitor (GDI) beta	immune response	Biological process	8356058
FCN2	2220	ficolin (collagen/fibrinogen domain containing lectin) 2	calcium-dependent protein binding	Molecular function	12421953
ACTR3	10096	ARP3 actin-related protein 3 homolog (yeast)	positive regulation of filopodium assembly	Biological process	-
MRPL18	29074	mitochondrial ribosomal protein L18	organelle organization	Biological process	-
DCTN3	11258	dynactin 3 (p22)	structural molecule activity	Molecular function	9722614
OR2H1	26716	olfactory receptor, family 2, subfamily H, member 1	plasma membrane	Cellular component	-
APPL2	55198	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2	cytoplasm	Cellular component	15016378
ACVR2A	92	activin A receptor, type IIA	protein serine/threonine kinase activity	Molecular function	-
TRIM36	55521	tripartite motif containing 36	regulation of cell cycle	Biological process	-
TMEM47	83604	transmembrane protein 47	cell-cell junction	Cellular component	-
IFI16	3428	interferon, gamma-inducible protein 16	regulation of autophagy	Biological process	21573174
MTNR1B	4544	melatonin receptor 1B	glucose homeostasis	Biological process	20668700
NGEF	25791	neuronal guanine nucleotide exchange factor	regulation of small GTPase mediated signal transduction	Biological process	-
PNKD	25953	paroxysmal nonkinesigenic dyskinesia	hydroxyacylglutathione hydrolase activity	Molecular function	-
LUZP1	7798	leucine zipper protein 1	nucleus	Cellular component	-
CUL7	9820	cullin 7	cytoplasm	Cellular component	-
CTNNBL1	56259	catenin, beta like 1	Prp19 complex	Cellular component	15175653
INS	3630	insulin	insulin receptor signaling pathway	Biological process	-
TUSC2	11334	tumor suppressor candidate 2	cell cycle	Biological process	-
RPL4	6124	ribosomal protein L4	viral life cycle	Biological process	-
MYOM1	8736	myomesin 1	striated muscle myosin thick filament	Cellular component	6537951
AVEN	57099	apoptosis, caspase activation inhibitor	endomembrane system	Cellular component	-
TAF1D	79101	TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa	transcription elongation from RNA polymerase I promoter	Biological process	-
SPEN	23013	spen family transcriptional repressor	sequence-specific DNA binding transcription factor activity	Molecular function	-
DDX21	9188	DEAD (Asp-Glu-Ala-Asp) box helicase 21	double-stranded RNA binding	Molecular function	-
HTRA2	27429	HtrA serine peptidase 2	positive regulation of protein targeting to mitochondrion	Biological process	24270810
IFNA4	3441	interferon, alpha 4	cytokine-mediated signaling pathway	Biological process	-
WHSC1L1	54904	Wolf-Hirschhorn syndrome candidate 1-like 1	transcription, DNA-templated	Biological process	-
LGALS12	85329	lectin, galactoside-binding, soluble, 12	regulation of lipid catabolic process	Biological process	-
DHCR7	1717	7-dehydrocholesterol reductase	multicellular organism growth	Biological process	-
PLCB1	23236	phospholipase C, beta 1 (phosphoinositide-specific)	signal transducer activity	Molecular function	-
CCL26	10344	chemokine (C-C motif) ligand 26	cell chemotaxis	Biological process	10373330
ZFAND2B	130617	zinc finger, AN1-type domain 2B	endoplasmic reticulum	Cellular component	-
F11R	50848	F11 receptor	extracellular exosome	Cellular component	19199708
BMP2	650	bone morphogenetic protein 2	positive regulation of bone mineralization	Biological process	18436533
POLR3GL	84265	polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like	transcription initiation from RNA polymerase III promoter	Biological process	-
FBXO4	26272	F-box protein 4	positive regulation of protein ubiquitination	Biological process	16275645
FLYWCH1	84256	FLYWCH-type zinc finger 1	nucleoplasm	Cellular component	-
VAMP3	9341	vesicle-associated membrane protein 3	recycling endosome	Cellular component	19061864
ARRB2	409	arrestin, beta 2	negative regulation of interleukin-1 beta production	Biological process	-
RHOU	58480	ras homolog family member U	GTP binding	Molecular function	-
TFAP2E	339488	transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)	sequence-specific DNA binding RNA polymerase II transcription factor activity	Molecular function	-
WNT2	7472	wingless-type MMTV integration site family member 2	proteinaceous extracellular matrix	Cellular component	-
CACNA1S	779	calcium channel, voltage-dependent, L type, alpha 1S subunit	skeletal muscle fiber development	Biological process	-
SUV420H2	84787	suppressor of variegation 4-20 homolog 2 (Drosophila)	transcription, DNA-templated	Biological process	-
IL10	3586	interleukin 10	regulation of gene expression	Biological process	9184696
TGFB1	7040	transforming growth factor, beta 1	negative regulation of extracellular matrix disassembly	Biological process	22269326
ARID1A	8289	AT rich interactive domain 1A (SWI-like)	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
BARX1	56033	BARX homeobox 1	nucleus	Cellular component	-
STAT1	6772	signal transducer and activator of transcription 1, 91kDa	metanephric mesenchymal cell proliferation involved in metanephros development	Biological process	-
NPR1	4881	natriuretic peptide receptor 1	negative regulation of cell growth	Biological process	12727915
ABCF2	10061	ATP-binding cassette, sub-family F (GCN20), member 2	metabolic process	Biological process	-
NOTCH1	4851	notch 1	enzyme inhibitor activity	Molecular function	-
INHBA	3624	inhibin, beta A	G1/S transition of mitotic cell cycle	Biological process	9884026
NPR2	4882	natriuretic peptide receptor 2	integral component of membrane	Cellular component	-
UQCRQ	27089	ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa	respiratory chain	Cellular component	-
JPH4	84502	junctophilin 4	regulation of synaptic plasticity	Biological process	-
APBB3	10307	amyloid beta (A4) precursor protein-binding, family B, member 3	beta-amyloid binding	Molecular function	-
ZNF234	10780	zinc finger protein 234	DNA binding	Molecular function	-
WNT2	7472	wingless-type MMTV integration site family member 2	lens development in camera-type eye	Biological process	16258938
RAB27A	5873	RAB27A, member RAS oncogene family	extracellular exosome	Cellular component	19056867
FBXW11	23291	F-box and WD repeat domain containing 11	centrosome	Cellular component	21399614
TXNDC5	81567	thioredoxin domain containing 5 (endoplasmic reticulum)	membrane organization	Biological process	-
SMARCC1	6599	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	nervous system development	Biological process	-
IRS1	3667	insulin receptor substrate 1	protein localization to nucleus	Biological process	-
CDC42EP4	23580	CDC42 effector protein (Rho GTPase binding) 4	positive regulation of pseudopodium assembly	Biological process	11035016
MST1	4485	macrophage stimulating 1	molecular_function	Molecular function	-
GATA4	2626	GATA binding protein 4	BMP signaling pathway	Biological process	-
ESRRA	2101	estrogen-related receptor alpha	regulation of osteoclast differentiation	Biological process	-
RAB11B	9230	RAB11B, member RAS oncogene family	GTP binding	Molecular function	16545962
CARHSP1	23589	calcium regulated heat stable protein 1, 24kDa	protein binding	Molecular function	25416956
RASD2	23551	RASD family, member 2	negative regulation of protein ubiquitination	Biological process	-
DPAGT1	1798	dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)	protein N-linked glycosylation via asparagine	Biological process	-
GSTT1	2952	glutathione S-transferase theta 1	xenobiotic metabolic process	Biological process	-
CCT8	10694	chaperonin containing TCP1, subunit 8 (theta)	protein binding	Molecular function	14532270
HMCN1	83872	hemicentin 1	cell junction	Cellular component	-
PDIA2	64714	protein disulfide isomerase family A, member 2	peptidyl-proline hydroxylation	Biological process	-
CORO1C	23603	coronin, actin binding protein, 1C	activation of GTPase activity	Biological process	-
TRIL	9865	TLR4 interactor with leucine-rich repeats	regulation of cytokine production involved in immune response	Biological process	19710467
PHOSPHO1	162466	phosphatase, orphan 1	small molecule metabolic process	Biological process	-
C14orf166	51637	chromosome 14 open reading frame 166	RNA polymerase II core binding	Molecular function	16950395
EPHA4	2043	EPH receptor A4	postsynaptic density	Cellular component	-
CAMK2D	817	calcium/calmodulin-dependent protein kinase II delta	relaxation of cardiac muscle	Biological process	12676814
CACNG4	27092	calcium channel, voltage-dependent, gamma subunit 4	endocytic vesicle membrane	Cellular component	-
RBP5	83758	retinol binding protein 5, cellular	protein binding	Molecular function	25416956
GGNBP1	449520	gametogenetin binding protein 1 (pseudogene)	Golgi apparatus	Cellular component	-
MCOLN1	57192	mucolipin 1	cellular iron ion homeostasis	Biological process	-
CYFIP2	26999	cytoplasmic FMR1 interacting protein 2	vascular endothelial growth factor receptor signaling pathway	Biological process	-
CYP4F2	8529	cytochrome P450, family 4, subfamily F, polypeptide 2	omega-hydroxylase P450 pathway	Biological process	-
GCK	2645	glucokinase (hexokinase 4)	cytosol	Cellular component	-
OR2A4	79541	olfactory receptor, family 2, subfamily A, member 4	detection of chemical stimulus involved in sensory perception	Biological process	-
THNSL2	55258	threonine synthase-like 2 (S. cerevisiae)	pyridoxal phosphate binding	Molecular function	17034760
PUM1	9698	pumilio RNA-binding family member 1	post-Golgi vesicle-mediated transport	Biological process	-
SCUBE1	80274	signal peptide, CUB domain, EGF-like 1	cell surface	Cellular component	12270931
CTCF	10664	CCCTC-binding factor (zinc finger protein)	regulation of histone acetylation	Biological process	-
DPYD	1806	dihydropyrimidine dehydrogenase	protein homodimerization activity	Molecular function	-
TRIM16	10626	tripartite motif containing 16	NACHT domain binding	Molecular function	16575408
BIRC6	57448	baculoviral IAP repeat containing 6	cysteine-type endopeptidase inhibitor activity	Molecular function	15200957
PSMC4	5704	proteasome (prosome, macropain) 26S subunit, ATPase, 4	proteasome accessory complex	Cellular component	-
FGR	2268	FGR proto-oncogene, Src family tyrosine kinase	protein binding	Molecular function	16273093
BAG4	9530	BCL2-associated athanogene 4	ubiquitin protein ligase binding	Molecular function	24270810
HAS1	3036	hyaluronan synthase 1	glycosaminoglycan biosynthetic process	Biological process	8798544
GK	2710	glycerol kinase	phosphorylation	Biological process	-
ADRA2A	150	adrenoceptor alpha 2A	adenylate cyclase-inhibiting adrenergic receptor signaling pathway	Biological process	10948191
INPP5K	51763	inositol polyphosphate-5-phosphatase K	negative regulation of glycogen biosynthetic process	Biological process	12556481
INTS12	57117	integrator complex subunit 12	snRNA processing	Biological process	16239144
CHRNA7	1139	cholinergic receptor, nicotinic, alpha 7 (neuronal)	positive regulation of angiogenesis	Biological process	12189247
TTLL1	25809	tubulin tyrosine ligase-like family member 1	cytoplasm	Cellular component	-
UBQLN1	29979	ubiquilin 1	negative regulation of store-operated calcium channel activity	Biological process	23307288
DOK2	9046	docking protein 2, 56kDa	receptor signaling protein activity	Molecular function	-
KRT18	3875	keratin 18, type I	tumor necrosis factor-mediated signaling pathway	Biological process	-
STEAP1	26872	six transmembrane epithelial antigen of the prostate 1	transporter activity	Molecular function	10588738
PAX2	5076	paired box 2	ureter maturation	Biological process	-
OMD	4958	osteomodulin	keratan sulfate biosynthetic process	Biological process	-
AVPR1A	552	arginine vasopressin receptor 1A	penile erection	Biological process	-
CDS2	8760	CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2	CDP-diacylglycerol biosynthetic process	Biological process	-
ATP6V0A2	23545	ATPase, H+ transporting, lysosomal V0 subunit a2	acrosomal vesicle	Cellular component	-
MYRIP	25924	myosin VIIA and Rab interacting protein	perinuclear region of cytoplasm	Cellular component	-
CYBA	1535	cytochrome b-245, alpha polypeptide	respiratory burst	Biological process	2243141
ERVS71-1	100862694	endogenous retrovirus group S71, member 1	integral component of membrane	Cellular component	-
PON1	5444	paraoxonase 1	positive regulation of cholesterol efflux	Biological process	15721011
IL13	3596	interleukin 13	cytokine activity	Molecular function	-
HOGA1	112817	4-hydroxy-2-oxoglutarate aldolase 1	extracellular exosome	Cellular component	23376485
CDIPT	10423	CDP-diacylglycerol--inositol 3-phosphatidyltransferase	CDP-diacylglycerol metabolic process	Biological process	-
KIR2DS5	3810	killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5	HLA-C specific inhibitory MHC class I receptor activity	Molecular function	8662091
CPE	1363	carboxypeptidase E	Wnt signaling pathway	Biological process	22824791
PIGK	10026	phosphatidylinositol glycan anchor biosynthesis, class K	cysteine-type peptidase activity	Molecular function	-
KPNB1	3837	karyopherin (importin) beta 1	enzyme binding	Molecular function	22701565
NCOA7	135112	nuclear receptor coactivator 7	intracellular	Cellular component	-
MPPED1	758	metallophosphoesterase domain containing 1	biological_process	Biological process	-
LGR4	55366	leucine-rich repeat containing G protein-coupled receptor 4	transmembrane signaling receptor activity	Molecular function	21727895
MAML3	55534	mastermind-like 3 (Drosophila)	gene expression	Biological process	-
KLF8	11279	Kruppel-like factor 8	regulation of transcription, DNA-templated	Biological process	-
GABRA4	2557	gamma-aminobutyric acid (GABA) A receptor, alpha 4	chloride channel activity	Molecular function	-
NCKAP1L	3071	NCK-associated protein 1-like	positive regulation of T cell proliferation	Biological process	-
THYN1	29087	thymocyte nuclear protein 1	nucleus	Cellular component	14601557
SHFM1	7979	split hand/foot malformation (ectrodactyly) type 1	nucleus	Cellular component	-
NOTCH2NL	388677	notch 2 N-terminal like	Notch signaling pathway	Biological process	-
IQGAP2	10788	IQ motif containing GTPase activating protein 2	cytosol	Cellular component	-
SORT1	6272	sortilin 1	nuclear membrane	Cellular component	-
SLC30A2	7780	solute carrier family 30 (zinc transporter), member 2	lysosomal membrane	Cellular component	17897319
ABCC4	10257	ATP-binding cassette, sub-family C (CFTR/MRP), member 4	response to organonitrogen compound	Biological process	-
SOX4	6659	SRY (sex determining region Y)-box 4	noradrenergic neuron differentiation	Biological process	-
PCDH7	5099	protocadherin 7	plasma membrane	Cellular component	9615233
GIPR	2696	gastric inhibitory polypeptide receptor	desensitization of G-protein coupled receptor protein signaling pathway	Biological process	-
TRIP6	7205	thyroid hormone receptor interactor 6	poly(A) RNA binding	Molecular function	22658674
CAMK2D	817	calcium/calmodulin-dependent protein kinase II delta	interferon-gamma-mediated signaling pathway	Biological process	-
SLC13A4	26266	solute carrier family 13 (sodium/sulfate symporter), member 4	sodium:sulfate symporter activity	Molecular function	10535998
TMPO	7112	thymopoietin	membrane	Cellular component	19946888
KRAS	3845	Kirsten rat sarcoma viral oncogene homolog	focal adhesion	Cellular component	21423176
ERLEC1	27248	endoplasmic reticulum lectin 1	endoplasmic reticulum lumen	Cellular component	16531414
PPP2R1A	5518	protein phosphatase 2, regulatory subunit A, alpha	regulation of DNA replication	Biological process	11007961
GPRC5B	51704	G protein-coupled receptor, class C, group 5, member B	positive regulation of inflammatory response	Biological process	-
DNAH17	8632	dynein, axonemal, heavy chain 17	ATPase activity	Molecular function	-
G6PC3	92579	glucose 6 phosphatase, catalytic, 3	gluconeogenesis	Biological process	-
TSPAN15	23555	tetraspanin 15	enzyme binding	Molecular function	23091066
SHANK3	85358	SH3 and multiple ankyrin repeat domains 3	positive regulation of long-term synaptic potentiation	Biological process	-
RAD1	5810	RAD1 checkpoint DNA exonuclease	DNA damage checkpoint	Biological process	21659603
CXCL16	58191	chemokine (C-X-C motif) ligand 16	plasma membrane	Cellular component	-
HAND1	9421	heart and neural crest derivatives expressed 1	cardiac septum morphogenesis	Biological process	19586923
CLEC6A	93978	C-type lectin domain family 6, member A	integral component of membrane	Cellular component	-
ANPEP	290	alanyl (membrane) aminopeptidase	aminopeptidase activity	Molecular function	-
PARP12	64761	poly (ADP-ribose) polymerase family, member 12	poly(A) RNA binding	Molecular function	22658674
AKT3	10000	v-akt murine thymoma viral oncogene homolog 3	signal transduction	Biological process	18524868
ROS1	6098	ROS proto-oncogene 1 , receptor tyrosine kinase	transmembrane receptor protein tyrosine kinase signaling pathway	Biological process	-
APOC2	344	apolipoprotein C-II	early endosome	Cellular component	-
UTP14A	10813	UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)	protein binding	Molecular function	15383276
AIF1	199	allograft inflammatory factor 1	response to axon injury	Biological process	-
NPAP1	23742	nuclear pore associated protein 1	nucleoplasm	Cellular component	-
SMPDL3A	10924	sphingomyelin phosphodiesterase, acid-like 3A	extracellular space	Cellular component	-
VCAM1	7412	vascular cell adhesion molecule 1	integrin binding	Molecular function	19738201
MAGEA3	4102	melanoma antigen family A3	endoplasmic reticulum	Cellular component	12097332
OSR2	116039	odd-skipped related transciption factor 2	positive regulation of epithelial cell proliferation	Biological process	-
CYP1A2	1544	cytochrome P450, family 1, subfamily A, polypeptide 2	post-embryonic development	Biological process	-
TMEM104	54868	transmembrane protein 104	molecular_function	Molecular function	-
TMEM18	129787	transmembrane protein 18	DNA binding	Molecular function	-
COL5A3	50509	collagen, type V, alpha 3	collagen catabolic process	Biological process	-
UBE2D1	7321	ubiquitin-conjugating enzyme E2D 1	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
IDI1	3422	isopentenyl-diphosphate delta isomerase 1	isoprenoid biosynthetic process	Biological process	-
LEFTY2	7044	left-right determination factor 2	multicellular organismal development	Biological process	-
UPB1	51733	ureidopropionase, beta	nucleobase-containing small molecule metabolic process	Biological process	-
COX7B2	170712	cytochrome c oxidase subunit VIIb2	hydrogen ion transmembrane transport	Biological process	-
CA4	762	carbonic anhydrase IV	protein binding	Molecular function	15563508
ATP6V1B2	526	ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2	extracellular exosome	Cellular component	19056867
SERPINF1	5176	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1	response to acidic pH	Biological process	-
TDRP	157695	testis development related protein	nucleus	Cellular component	20170638
DOHH	83475	deoxyhypusine hydroxylase/monooxygenase	deoxyhypusine monooxygenase activity	Molecular function	-
KCNJ18	100134444	potassium channel, inwardly rectifying subfamily J, member 18	plasma membrane	Cellular component	20074522
TCF4	6925	transcription factor 4	transcription factor complex	Cellular component	8978694
ENPEP	2028	glutamyl aminopeptidase (aminopeptidase A)	metallopeptidase activity	Molecular function	-
SLC27A1	376497	solute carrier family 27 (fatty acid transporter), member 1	phosphatidylethanolamine biosynthetic process	Biological process	19523918
PRKG1	5592	protein kinase, cGMP-dependent, type I	cytoplasm	Cellular component	21402151
AGT	183	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	blood vessel remodeling	Biological process	10406457
OSGIN1	29948	oxidative stress induced growth inhibitor 1	cell differentiation	Biological process	-
ATP6V0D2	245972	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2	phagocytic vesicle membrane	Cellular component	-
YWHAB	7529	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta	vascular endothelial growth factor receptor signaling pathway	Biological process	-
SMAD5	4090	SMAD family member 5	cytoplasm	Cellular component	-
ANO9	338440	anoctamin 9	calcium activated phosphatidylserine scrambling	Biological process	-
OSM	5008	oncostatin M	peripheral nervous system development	Biological process	-
CD70	970	CD70 molecule	tumor necrosis factor receptor binding	Molecular function	-
PTCH1	5727	patched 1	negative regulation of osteoblast differentiation	Biological process	16229683
LCLAT1	253558	lysocardiolipin acyltransferase 1	glycerophospholipid biosynthetic process	Biological process	-
CRIPT	9419	cysteine-rich PDZ-binding protein	cell junction	Cellular component	-
SURF4	6836	surfeit 4	endoplasmic reticulum-Golgi intermediate compartment membrane	Cellular component	-
LGALS3	3958	lectin, galactoside-binding, soluble, 3	RNA splicing	Biological process	-
EPHB3	2049	EPH receptor B3	cell migration	Biological process	15536074
DEGS1	8560	delta(4)-desaturase, sphingolipid 1	small molecule metabolic process	Biological process	-
TRPV4	59341	transient receptor potential cation channel, subfamily V, member 4	cortical microtubule organization	Biological process	-
BCL2	596	B-cell CLL/lymphoma 2	response to toxic substance	Biological process	16307838
TRAF6	7189	TNF receptor-associated factor 6, E3 ubiquitin protein ligase	regulation of immunoglobulin secretion	Biological process	-
BDKRB2	624	bradykinin receptor B2	regulation of vascular permeability	Biological process	17077303
N4BP3	23138	NEDD4 binding protein 3	cytoplasmic vesicle membrane	Cellular component	-
CLCN3	1182	chloride channel, voltage-sensitive 3	transmembrane transport	Biological process	-
KCNMA1	3778	potassium channel, calcium activated large conductance subfamily M alpha, member 1	response to carbon monoxide	Biological process	18180950
C16orf72	29035	chromosome 16 open reading frame 72	protein binding	Molecular function	25416956
DLL1	28514	delta-like 1 (Drosophila)	regulation of cell adhesion	Biological process	11912004
PEX11A	8800	peroxisomal biogenesis factor 11 alpha	protein homodimerization activity	Molecular function	20826455
ZFP64	55734	ZFP64 zinc finger protein	transcription, DNA-templated	Biological process	-
BIRC5	332	baculoviral IAP repeat containing 5	cobalt ion binding	Molecular function	10949039
KLHL14	57565	kelch-like family member 14	endoplasmic reticulum membrane	Cellular component	-
RACGAP1	29127	Rac GTPase activating protein 1	microtubule binding	Molecular function	11782313
LAMB3	3914	laminin, beta 3	cell adhesion	Biological process	-
WBP11	51729	WW domain binding protein 11	regulation of catalytic activity	Biological process	-
SLC25A19	60386	solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19	deoxynucleotide transmembrane transporter activity	Molecular function	11226231
ZC3H18	124245	zinc finger CCCH-type containing 18	poly(A) RNA binding	Molecular function	22658674
ELANE	1991	elastase, neutrophil expressed	peptidase activity	Molecular function	11907569
ZBED9	114821	zinc finger, BED-type containing 9	nucleic acid binding	Molecular function	-
PIK3CA	5290	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	kinase activity	Molecular function	-
BROX	148362	BRO1 domain and CAAX motif containing	extracellular exosome	Cellular component	19056867
ADH1A	124	alcohol dehydrogenase 1A (class I), alpha polypeptide	ethanol oxidation	Biological process	-
ZNF606	80095	zinc finger protein 606	nucleoplasm	Cellular component	-
NUP62	23636	nucleoporin 62kDa	Flemming body	Cellular component	19166812
JAK2	3717	Janus kinase 2	histone binding	Molecular function	19783980
UBE2G2	7327	ubiquitin-conjugating enzyme E2G 2	negative regulation of retrograde protein transport, ER to cytosol	Biological process	25660456
TMEM106C	79022	transmembrane protein 106C	biological_process	Biological process	-
ST3GAL3	6487	ST3 beta-galactoside alpha-2,3-sialyltransferase 3	protein O-linked glycosylation	Biological process	-
ANXA6	309	annexin A6	calcium-dependent protein binding	Molecular function	15226301
NQO2	4835	NAD(P)H dehydrogenase, quinone 2	memory	Biological process	-
TH	7054	tyrosine hydroxylase	nucleus	Cellular component	-
SRGAP3	9901	SLIT-ROBO Rho GTPase activating protein 3	cytoplasm	Cellular component	-
CTSG	1511	cathepsin G	extracellular matrix disassembly	Biological process	-
SMTN	6525	smoothelin	smooth muscle contraction	Biological process	8707825
MYOM3	127294	myomesin 3	M band	Cellular component	-
PSMB10	5699	proteasome (prosome, macropain) subunit, beta type, 10	programmed cell death	Biological process	-
CREB1	1385	cAMP responsive element binding protein 1	sequence-specific DNA binding transcription factor activity	Molecular function	8798441
ADIPOQ	9370	adiponectin, C1Q and collagen domain containing	cell surface	Cellular component	10982546
RASIP1	54922	Ras interacting protein 1	vasculogenesis	Biological process	-
BTK	695	Bruton agammaglobulinemia tyrosine kinase	metal ion binding	Molecular function	-
OR5AC2	81050	olfactory receptor, family 5, subfamily AC, member 2	plasma membrane	Cellular component	-
RPRD1B	58490	regulation of nuclear pre-mRNA domain containing 1B	DNA-directed RNA polymerase II, holoenzyme	Cellular component	22231121
PLK3	1263	polo-like kinase 3	positive regulation of intracellular protein transport	Biological process	20951827
HLA-F	3134	major histocompatibility complex, class I, F	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent	Biological process	-
BTG1	694	B-cell translocation gene 1, anti-proliferative	transcription cofactor activity	Molecular function	11420681
OR10H4	126541	olfactory receptor, family 10, subfamily H, member 4	G-protein coupled receptor activity	Molecular function	-
DAG1	1605	dystroglycan 1 (dystrophin-associated glycoprotein 1)	viral entry into host cell	Biological process	-
CES2	8824	carboxylesterase 2	methylumbelliferyl-acetate deacetylase activity	Molecular function	-
OTUD7B	56957	OTU deubiquitinase 7B	Lys48-specific deubiquitinase activity	Molecular function	21097510
IMPDH2	3615	IMP (inosine 5'-monophosphate) dehydrogenase 2	GMP biosynthetic process	Biological process	-
MAP3K2	10746	mitogen-activated protein kinase kinase kinase 2	MAP kinase kinase kinase activity	Molecular function	-
HEY1	23462	hes-related family bHLH transcription factor with YRPW motif 1	cytoplasm	Cellular component	-
CCL2	6347	chemokine (C-C motif) ligand 2	positive regulation of leukocyte mediated cytotoxicity	Biological process	-
POLD2	5425	polymerase (DNA directed), delta 2, accessory subunit	DNA replication	Biological process	8530069
INPP5A	3632	inositol polyphosphate-5-phosphatase, 40kDa	extracellular exosome	Cellular component	23376485
GRIA3	2892	glutamate receptor, ionotropic, AMPA 3	endocytic vesicle membrane	Cellular component	-
ATG12	9140	autophagy related 12	autophagosome assembly	Biological process	-
RPS28	6234	ribosomal protein S28	small ribosomal subunit	Cellular component	15883184
CDK5	1020	cyclin-dependent kinase 5	regulation of cell migration	Biological process	-
SYNE1	23345	spectrin repeat containing, nuclear envelope 1	cytoskeletal anchoring at nuclear membrane	Biological process	18396275
ASZ1	136991	ankyrin repeat, SAM and basic leucine zipper domain containing 1	multicellular organismal development	Biological process	-
MAPK11	5600	mitogen-activated protein kinase 11	toll-like receptor 2 signaling pathway	Biological process	-
KCNQ5	56479	potassium channel, voltage gated KQT-like subfamily Q, member 5	voltage-gated potassium channel complex	Cellular component	-
UNC13B	10497	unc-13 homolog B (C. elegans)	apoptotic process	Biological process	10233166
PLA2G10	8399	phospholipase A2, group X	negative regulation of sequence-specific DNA binding transcription factor activity	Biological process	20844270
CENPF	1063	centromere protein F, 350/400kDa	regulation of G2/M transition of mitotic cell cycle	Biological process	12154071
HPGD	3248	hydroxyprostaglandin dehydrogenase 15-(NAD)	arachidonic acid metabolic process	Biological process	-
BST2	684	bone marrow stromal cell antigen 2	negative regulation of cell migration	Biological process	22065321
ST8SIA2	8128	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	cellular protein metabolic process	Biological process	-
GBE1	2632	glucan (1,4-alpha-), branching enzyme 1	glucose metabolic process	Biological process	-
DNMT3A	1788	DNA (cytosine-5-)-methyltransferase 3 alpha	DNA binding	Molecular function	12138111
MAP2K6	5608	mitogen-activated protein kinase kinase 6	signal transduction by protein phosphorylation	Biological process	-
ACMSD	130013	aminocarboxymuconate semialdehyde decarboxylase	tryptophan catabolic process	Biological process	-
EIF2AK3	9451	eukaryotic translation initiation factor 2-alpha kinase 3	regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	Biological process	23000344
SLC6A12	6539	solute carrier family 6 (neurotransmitter transporter), member 12	transport	Biological process	7861179
PMAIP1	5366	phorbol-12-myristate-13-acetate-induced protein 1	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	Biological process	-
ALDH18A1	5832	aldehyde dehydrogenase 18 family, member A1	citrulline biosynthetic process	Biological process	11092761
ITGB1BP1	9270	integrin beta 1 binding protein 1	positive regulation of Notch signaling pathway	Biological process	20616313
ETV3L	440695	ets variant 3-like	sequence-specific DNA binding RNA polymerase II transcription factor activity	Molecular function	-
CMPK1	51727	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic	'de novo' pyrimidine nucleobase biosynthetic process	Biological process	-
DRD5	1816	dopamine receptor D5	activation of adenylate cyclase activity	Biological process	9457173
FAM184A	79632	family with sequence similarity 184, member A	protein binding	Molecular function	24407287
ADAMTS3	9508	ADAM metallopeptidase with thrombospondin type 1 motif, 3	endopeptidase activity	Molecular function	24552833
NDUFC1	4717	NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa	cellular metabolic process	Biological process	-
FADD	8772	Fas (TNFRSF6)-associated via death domain	tumor necrosis factor receptor binding	Molecular function	-
CITED1	4435	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1	response to insulin	Biological process	-
CTBP1	1487	C-terminal binding protein 1	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Molecular function	-
EYA4	2070	EYA transcriptional coactivator and phosphatase 4	visual perception	Biological process	9887327
PFDN1	5201	prefoldin subunit 1	protein folding	Biological process	-
NPAT	4863	nuclear protein, ataxia-telangiectasia locus	regulation of gene expression	Biological process	15988025
CDCA2	157313	cell division cycle associated 2	positive regulation of protein dephosphorylation	Biological process	22801782
RAB3GAP2	25782	RAB3 GTPase activating protein subunit 2 (non-catalytic)	plasma membrane	Cellular component	-
TRAF6	7189	TNF receptor-associated factor 6, E3 ubiquitin protein ligase	toll-like receptor signaling pathway	Biological process	-
SNRPD2	6633	small nuclear ribonucleoprotein D2 polypeptide 16.5kDa	extracellular exosome	Cellular component	20458337
DRD5	1816	dopamine receptor D5	wound healing	Biological process	-
FZD1	8321	frizzled class receptor 1	outflow tract morphogenesis	Biological process	-
MAPK3	5595	mitogen-activated protein kinase 3	ATP binding	Molecular function	-
EEPD1	80820	endonuclease/exonuclease/phosphatase family domain containing 1	DNA binding	Molecular function	-
SULT1C4	27233	sulfotransferase family, cytosolic, 1C, member 4	xenobiotic metabolic process	Biological process	-
ANTXR2	118429	anthrax toxin receptor 2	toxin transport	Biological process	-
ACSL1	2180	acyl-CoA synthetase long-chain family member 1	xenobiotic catabolic process	Biological process	-
SRC	6714	SRC proto-oncogene, non-receptor tyrosine kinase	intracellular signal transduction	Biological process	15248232
STMND1	401236	stathmin domain containing 1	regulation of microtubule polymerization or depolymerization	Biological process	-
VIM	7431	vimentin	extracellular exosome	Cellular component	20458337
UBE2V2	7336	ubiquitin-conjugating enzyme E2 variant 2	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
PRKD1	5587	protein kinase D1	protein kinase D signaling	Biological process	20497126
VPS11	55823	vacuolar protein sorting 11 homolog (S. cerevisiae)	intracellular protein transport	Biological process	-
EMC6	83460	ER membrane protein complex subunit 6	integral component of omegasome membrane	Cellular component	23182941
OR8K3	219473	olfactory receptor, family 8, subfamily K, member 3 (gene/pseudogene)	olfactory receptor activity	Molecular function	-
SNCA	6622	synuclein, alpha (non A4 component of amyloid precursor)	regulation of reactive oxygen species biosynthetic process	Biological process	24252804
GALNT11	63917	polypeptide N-acetylgalactosaminyltransferase 11	determination of left/right symmetry	Biological process	-
ETV4	2118	ets variant 4	cell differentiation	Biological process	-
PLCB2	5330	phospholipase C, beta 2	cytosol	Cellular component	-
CAD	790	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	Molecular function	-
TMEM129	92305	transmembrane protein 129, E3 ubiquitin protein ligase	endoplasmic reticulum	Cellular component	24807418
EGR1	1958	early growth response 1	oligodendrocyte differentiation	Biological process	-
VMP1	81671	vacuole membrane protein 1	regulation of autophagy	Biological process	-
KIAA0319L	79932	KIAA0319-like	extracellular exosome	Cellular component	23376485
GULP1	51454	GULP, engulfment adaptor PTB domain containing 1	lipid transport	Biological process	-
ZNRF3	84133	zinc and ring finger 3	plasma membrane	Cellular component	-
ZBTB12	221527	zinc finger and BTB domain containing 12	metal ion binding	Molecular function	-
RNF214	257160	ring finger protein 214	zinc ion binding	Molecular function	-
SLC26A9	115019	solute carrier family 26 (anion exchanger), member 9	chloride transmembrane transport	Biological process	-
CCL24	6369	chemokine (C-C motif) ligand 24	inflammatory response	Biological process	-
MAP1LC3B2	643246	microtubule-associated protein 1 light chain 3 beta 2	microtubule	Cellular component	-
WTAP	9589	Wilms tumor 1 associated protein	nucleoplasm	Cellular component	-
KCNMB4	27345	potassium channel subfamily M regulatory beta subunit 4	calcium-activated potassium channel activity	Molecular function	10692449
IGF1	3479	insulin-like growth factor 1 (somatomedin C)	extrinsic apoptotic signaling pathway in absence of ligand	Biological process	-
ACTN1	87	actinin, alpha 1	fascia adherens	Cellular component	-
RNF126	55658	ring finger protein 126	protein K48-linked ubiquitination	Biological process	-
RGS2	5997	regulator of G-protein signaling 2	relaxation of cardiac muscle	Biological process	-
HNRNPF	3185	heterogeneous nuclear ribonucleoprotein F	protein binding	Molecular function	17932509
TAF5L	27097	TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa	regulation of transcription, DNA-templated	Biological process	-
CBX5	23468	chromobox homolog 5	methylated histone binding	Molecular function	19783980
ZFYVE16	9765	zinc finger, FYVE domain containing 16	signal transduction	Biological process	11546807
PI3	5266	peptidase inhibitor 3, skin-derived	endopeptidase inhibitor activity	Molecular function	2394696
OLFM4	10562	olfactomedin 4	perinuclear region of cytoplasm	Cellular component	16566923
PPP4R1	9989	protein phosphatase 4, regulatory subunit 1	dephosphorylation	Biological process	-
ABAT	18	4-aminobutyrate aminotransferase	4-aminobutyrate transaminase complex	Cellular component	15528998
RET	5979	ret proto-oncogene	ureter maturation	Biological process	-
NMD3	51068	NMD3 ribosome export adaptor	ribosomal large subunit binding	Molecular function	12773398
PRMT7	54496	protein arginine methyltransferase 7	histone binding	Molecular function	15494416
PBX2	5089	pre-B-cell leukemia homeobox 2	chromatin binding	Molecular function	-
INA	9118	internexin neuronal intermediate filament protein, alpha	substantia nigra development	Biological process	22926577
SMYD3	64754	SET and MYND domain containing 3	cytoplasm	Cellular component	-
CDK9	1025	cyclin-dependent kinase 9	positive regulation of mRNA 3'-UTR binding	Biological process	19575011
OR12D3	81797	olfactory receptor, family 12, subfamily D, member 3	G-protein coupled receptor signaling pathway	Biological process	-
ZNF451	26036	zinc finger protein 451	metal ion binding	Molecular function	-
UBL7	84993	ubiquitin-like 7	protein binding	Molecular function	16189514
NOTCH1	4851	notch 1	positive regulation of cardiac muscle cell proliferation	Biological process	-
TNFRSF18	8784	tumor necrosis factor receptor superfamily, member 18	integral component of plasma membrane	Cellular component	-
DRD2	1813	dopamine receptor D2	regulation of cAMP metabolic process	Biological process	8666994
HLA-DRB5	3127	major histocompatibility complex, class II, DR beta 5	integral component of lumenal side of endoplasmic reticulum membrane	Cellular component	-
LHX9	56956	LIM homeobox 9	transcription corepressor activity	Molecular function	-
VGF	7425	VGF nerve growth factor inducible	response to cAMP	Biological process	10381005
KITLG	4254	KIT ligand	extracellular space	Cellular component	-
NXF1	10482	nuclear RNA export factor 1	nuclear pore	Cellular component	-
BCL6	604	B-cell CLL/lymphoma 6	negative regulation of cell proliferation	Biological process	-
LHX5	64211	LIM homeobox 5	nucleus	Cellular component	-
SMARCD3	6604	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3	nuclear hormone receptor binding	Molecular function	14701856
CTSH	1512	cathepsin H	protein binding	Molecular function	15127951
TRIM35	23087	tripartite motif containing 35	apoptotic process	Biological process	-
ID3	3399	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	central nervous system development	Biological process	-
RPL38	6169	ribosomal protein L38	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Biological process	-
IGFALS	3483	insulin-like growth factor binding protein, acid labile subunit	insulin-like growth factor binding	Molecular function	1379671
PTPN11	5781	protein tyrosine phosphatase, non-receptor type 11	protein domain specific binding	Molecular function	-
LEP	3952	leptin	negative regulation of cartilage development	Biological process	-
TAS2R3	50831	taste receptor, type 2, member 3	signal transduction	Biological process	10761934
RUVBL2	10856	RuvB-like AAA ATPase 2	positive regulation of transcription from RNA polymerase II promoter	Biological process	23637611
ILVBL	10994	ilvB (bacterial acetolactate synthase)-like	magnesium ion binding	Molecular function	-
HCLS1	3059	hematopoietic cell-specific Lyn substrate 1	response to hormone	Biological process	-
DNM2	1785	dynamin 2	G2/M transition of mitotic cell cycle	Biological process	7590285
KIR2DL3	3804	killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3	immune response	Biological process	7749980
PBX1	5087	pre-B-cell leukemia homeobox 1	protein binding	Molecular function	10052460
RRN3	54700	RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)	homeostasis of number of cells	Biological process	-
LPO	4025	lactoperoxidase	heme binding	Molecular function	-
XRCC5	7520	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	cell proliferation	Biological process	-
GRM7	2917	glutamate receptor, metabotropic 7	postsynaptic membrane	Cellular component	-
MLN	4295	motilin	hormone activity	Molecular function	-
SLC29A4	222962	solute carrier family 29 (equilibrative nucleoside transporter), member 4	nucleoside transmembrane transport	Biological process	-
AKR1C3	8644	aldo-keto reductase family 1, member C3	phenanthrene 9,10-monooxygenase activity	Molecular function	21851338
OR52A4P	390053	olfactory receptor, family 52, subfamily A, member 4, pseudogene	plasma membrane	Cellular component	-
DCLK1	9201	doublecortin-like kinase 1	ATP binding	Molecular function	-
RETN	56729	resistin	negative regulation of feeding behavior	Biological process	-
ALYREF	10189	Aly/REF export factor	nucleus	Cellular component	-
HCRT	3060	hypocretin (orexin) neuropeptide precursor	positive regulation of cytosolic calcium ion concentration	Biological process	-
STARD6	147323	StAR-related lipid transfer (START) domain containing 6	lipid binding	Molecular function	-
NUBP1	4682	nucleotide binding protein 1	plasma membrane	Cellular component	-
ZFP41	286128	ZFP41 zinc finger protein	DNA binding	Molecular function	-
STIM2	57620	stromal interaction molecule 2	cellular calcium ion homeostasis	Biological process	18160041
ARID3A	1820	AT rich interactive domain 3A (BRIGHT-like)	cytoplasm	Cellular component	-
TIRAP	114609	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	positive regulation of ERK1 and ERK2 cascade	Biological process	11544529
SCAND2P	54581	SCAN domain containing 2 pseudogene	sequence-specific DNA binding transcription factor activity	Molecular function	-
XRN2	22803	5'-3' exoribonuclease 2	poly(A) RNA binding	Molecular function	22658674
BBS2	583	Bardet-Biedl syndrome 2	sperm axoneme assembly	Biological process	-
NOD2	64127	nucleotide-binding oligomerization domain containing 2	toll-like receptor 10 signaling pathway	Biological process	-
NUP62	23636	nucleoporin 62kDa	hormone-mediated signaling pathway	Biological process	15625236
BBS12	166379	Bardet-Biedl syndrome 12	protein binding	Molecular function	20080638
OR2T2	401992	olfactory receptor, family 2, subfamily T, member 2	plasma membrane	Cellular component	-
ITFG3	83986	integrin alpha FG-GAP repeat containing 3	biological_process	Biological process	-
CDC23	8697	cell division cycle 23	mitotic spindle assembly checkpoint	Biological process	-
SRD5A3	79644	steroid 5 alpha-reductase 3	polyprenol catabolic process	Biological process	20637498
ID2	3398	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	protein dimerization activity	Molecular function	-
AGT	183	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	angiotensin-mediated drinking behavior	Biological process	-
STK16	8576	serine/threonine kinase 16	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
KYNU	8942	kynureninase	protein homodimerization activity	Molecular function	11985583
NUDT16	131870	nudix (nucleoside diphosphate linked moiety X)-type motif 16	manganese ion binding	Molecular function	17567574
FAM161A	84140	family with sequence similarity 161, member A	centrosome	Cellular component	21399614
DNAJC2	27000	DnaJ (Hsp40) homolog, subfamily C, member 2	negative regulation of cell growth	Biological process	-
EIF4B	1975	eukaryotic translation initiation factor 4B	gene expression	Biological process	-
MAPK8IP3	23162	mitogen-activated protein kinase 8 interacting protein 3	positive regulation of neuron differentiation	Biological process	-
ULK1	8408	unc-51 like autophagy activating kinase 1	pre-autophagosomal structure	Cellular component	-
OPN1MW2	728458	opsin 1 (cone pigments), medium-wave-sensitive 2	photoreceptor outer segment membrane	Cellular component	-
FAN1	22909	FANCD2/FANCI-associated nuclease 1	phosphodiesterase I activity	Molecular function	-
CAV1	857	caveolin 1, caveolae protein, 22kDa	VCP-NPL4-UFD1 AAA ATPase complex	Cellular component	24089527
APOL2	23780	apolipoprotein L, 2	extracellular region	Cellular component	-
RFTN2	130132	raftlin family member 2	response to exogenous dsRNA	Biological process	-
EPRS	2058	glutamyl-prolyl-tRNA synthetase	protein complex assembly	Biological process	8188258
MAP3K12	7786	mitogen-activated protein kinase kinase kinase 12	peptidyl-serine phosphorylation	Biological process	-
MED20	9477	mediator complex subunit 20	transcription, DNA-templated	Biological process	9933582
PSMB1	5689	proteasome (prosome, macropain) subunit, beta type, 1	proteasome core complex	Cellular component	-
ARHGEF5	7984	Rho guanine nucleotide exchange factor (GEF) 5	myeloid dendritic cell chemotaxis	Biological process	-
OLFM4	10562	olfactomedin 4	regulation of neutrophil extravasation	Biological process	23922742
DHRS11	79154	dehydrogenase/reductase (SDR family) member 11	oxidation-reduction process	Biological process	-
SYTL3	94120	synaptotagmin-like 3	syntaxin binding	Molecular function	-
CD109	135228	CD109 molecule	plasma membrane	Cellular component	-
GRHL3	57822	grainyhead-like 3 (Drosophila)	establishment of planar polarity	Biological process	-
AMBRA1	55626	autophagy/beclin-1 regulator 1	mitochondrion	Cellular component	21753002
SMG6	23293	SMG6 nonsense mediated mRNA decay factor	cytoplasm	Cellular component	-
KAT2A	2648	K(lysine) acetyltransferase 2A	Ada2/Gcn5/Ada3 transcription activator complex	Cellular component	18838386
TIGD5	84948	tigger transposable element derived 5	DNA binding	Molecular function	-
PDLIM2	64236	PDZ and LIM domain 2 (mystique)	stress fiber	Cellular component	-
MAP3K15	389840	mitogen-activated protein kinase kinase kinase 15	MAPK cascade	Biological process	-
SETMAR	6419	SET domain and mariner transposase fusion gene	DNA topoisomerase binding	Molecular function	18790802
RELA	5970	v-rel avian reticuloendotheliosis viral oncogene homolog A	T cell receptor signaling pathway	Biological process	-
EIF1AD	84285	eukaryotic translation initiation factor 1A domain containing	translation initiation factor activity	Molecular function	-
DNAJB2	3300	DnaJ (Hsp40) homolog, subfamily B, member 2	response to unfolded protein	Biological process	1599432
TCF7L2	6934	transcription factor 7-like 2 (T-cell specific, HMG-box)	pancreas development	Biological process	18216022
FOXC2	2303	forkhead box C2	positive regulation of cell migration involved in sprouting angiogenesis	Biological process	-
RHOH	399	ras homolog family member H	kinase inhibitor activity	Molecular function	11809807
CBLC	23624	Cbl proto-oncogene C, E3 ubiquitin protein ligase	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	14661060
PSG11	5680	pregnancy specific beta-1-glycoprotein 11	extracellular region	Cellular component	-
PSME1	5720	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition	Biological process	-
MEN1	4221	multiple endocrine neoplasia I	sequence-specific DNA binding	Molecular function	-
CDK5	1020	cyclin-dependent kinase 5	axon	Cellular component	-
SP9	100131390	Sp9 transcription factor	regulation of transcription, DNA-templated	Biological process	-
TNFSF18	8995	tumor necrosis factor (ligand) superfamily, member 18	positive regulation of NF-kappaB transcription factor activity	Biological process	-
MRPL30	51263	mitochondrial ribosomal protein L30	mitochondrial translation	Biological process	-
DNAJB5	25822	DnaJ (Hsp40) homolog, subfamily B, member 5	nucleus	Cellular component	-
LSM14A	26065	LSM14A, SCD6 homolog A (S. cerevisiae)	double-stranded DNA binding	Molecular function	-
KCNJ3	3760	potassium channel, inwardly rectifying subfamily J, member 3	integral component of plasma membrane	Cellular component	-
POLR3A	11128	polymerase (RNA) III (DNA directed) polypeptide A, 155kDa	defense response to virus	Biological process	-
TPCN2	219931	two pore segment channel 2	transmembrane transport	Biological process	-
VBP1	7411	von Hippel-Lindau binding protein 1	nucleus	Cellular component	-
CCNB1	891	cyclin B1	negative regulation of gene expression	Biological process	-
PTPN11	5781	protein tyrosine phosphatase, non-receptor type 11	insulin receptor signaling pathway	Biological process	-
SLC25A6	293	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6	small molecule metabolic process	Biological process	-
YWHAH	7533	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta	cytosol	Cellular component	-
ARHGEF2	9181	Rho/Rac guanine nucleotide exchange factor (GEF) 2	cellular response to muramyl dipeptide	Biological process	21887730
ATP7A	538	ATPase, Cu++ transporting, alpha polypeptide	endoplasmic reticulum	Cellular component	-
ELOVL3	83401	ELOVL fatty acid elongase 3	unsaturated fatty acid biosynthetic process	Biological process	-
CD46	4179	CD46 molecule, complement regulatory protein	complement binding	Molecular function	-
CD24	100133941	CD24 molecule	regulation of cytokine-mediated signaling pathway	Biological process	16390867
ACACA	31	acetyl-CoA carboxylase alpha	long-chain fatty-acyl-CoA biosynthetic process	Biological process	-
BMP4	652	bone morphogenetic protein 4	type B pancreatic cell development	Biological process	11865031
PCDHGA3	56112	protocadherin gamma subfamily A, 3	calcium ion binding	Molecular function	-
ARSE	415	arylsulfatase E (chondrodysplasia punctata 1)	extracellular exosome	Cellular component	19056867
ATP6V1B1	525	ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1	ATP hydrolysis coupled proton transport	Biological process	-
KNDC1	85442	kinase non-catalytic C-lobe domain (KIND) containing 1	regulation of dendrite morphogenesis	Biological process	-
ADCYAP1	116	adenylate cyclase activating polypeptide 1 (pituitary)	extracellular space	Cellular component	-
DUSP10	11221	dual specificity phosphatase 10	negative regulation of respiratory burst involved in inflammatory response	Biological process	-
HNRNPH1	3187	heterogeneous nuclear ribonucleoprotein H1 (H)	regulation of RNA splicing	Biological process	16946708
LRTOMT	220074	leucine rich transmembrane and O-methyltransferase domain containing	catecholamine catabolic process	Biological process	18794526
CASC3	22794	cancer susceptibility candidate 3	cytosol	Cellular component	-
TNF	7124	tumor necrosis factor	response to activity	Biological process	-
PROP1	5626	PROP paired-like homeobox 1	somatotropin secreting cell differentiation	Biological process	-
C1orf198	84886	chromosome 1 open reading frame 198	cytoplasm	Cellular component	-
CRYAA	1409	crystallin, alpha A	response to stimulus	Biological process	-
MBIP	51562	MAP3K12 binding inhibitory protein 1	cytoplasm	Cellular component	-
ACSL5	51703	acyl-CoA synthetase long-chain family member 5	integral component of membrane	Cellular component	-
SAMD11	148398	sterile alpha motif domain containing 11	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
NUP98	4928	nucleoporin 98kDa	small GTPase mediated signal transduction	Biological process	-
ALDOA	226	aldolase A, fructose-bisphosphate	protein homotetramerization	Biological process	-
WDPCP	51057	WD repeat containing planar cell polarity effector	palate development	Biological process	-
KIAA0101	9768	KIAA0101	nucleus	Cellular component	-
RHEB	6009	Ras homolog enriched in brain	gene expression	Biological process	-
GSK3B	2932	glycogen synthase kinase 3 beta	protein phosphorylation	Biological process	11035810
TMEM129	92305	transmembrane protein 129, E3 ubiquitin protein ligase	endoplasmic reticulum membrane	Cellular component	-
DPP7	29952	dipeptidyl-peptidase 7	proteolysis	Biological process	-
TSKU	25987	tsukushi, small leucine rich proteoglycan	corpus callosum morphogenesis	Biological process	-
NUPL1	9818	nucleoporin like 1	regulation of glucose transport	Biological process	-
WHSC1	7468	Wolf-Hirschhorn syndrome candidate 1	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
COL4A5	1287	collagen, type IV, alpha 5	collagen catabolic process	Biological process	-
SETD6	79918	SET domain containing 6	nucleus	Cellular component	-
PDZD4	57595	PDZ domain containing 4	protein ubiquitination	Biological process	-
AQP7	364	aquaporin 7	cellular water homeostasis	Biological process	-
STK35	140901	serine/threonine kinase 35	cytoplasm	Cellular component	-
SOX10	6663	SRY (sex determining region Y)-box 10	transcription from RNA polymerase II promoter	Biological process	-
NME7	29922	NME/NM23 family member 7	intraciliary transport	Biological process	-
F7	2155	coagulation factor VII (serum prothrombin conversion accelerator)	positive regulation of blood coagulation	Biological process	-
BBS1	582	Bardet-Biedl syndrome 1	centrosome	Cellular component	-
BCL2L12	83596	BCL2-like 12 (proline rich)	protein binding	Molecular function	19376117
SLC26A9	115019	solute carrier family 26 (anion exchanger), member 9	plasma membrane	Cellular component	-
FYN	2534	FYN proto-oncogene, Src family tyrosine kinase	intracellular signal transduction	Biological process	1361685
PRKDC	5591	protein kinase, DNA-activated, catalytic polypeptide	intrinsic apoptotic signaling pathway in response to DNA damage	Biological process	-
ROCK2	9475	Rho-associated, coiled-coil containing protein kinase 2	neural tube closure	Biological process	-
RASA1	5921	RAS p21 protein activator (GTPase activating protein) 1	regulation of actin filament polymerization	Biological process	8344248
ROBO4	54538	roundabout, axon guidance receptor, homolog 4 (Drosophila)	extracellular exosome	Cellular component	23376485
RPH3AL	9501	rabphilin 3A-like (without C2 domains)	positive regulation of protein secretion	Biological process	-
FHL2	2274	four and a half LIM domains 2	focal adhesion	Cellular component	-
MNAT1	4331	MNAT CDK-activating kinase assembly factor 1	7-methylguanosine mRNA capping	Biological process	-
CYFIP1	23191	cytoplasmic FMR1 interacting protein 1	axon extension	Biological process	16260607
RPTOR	57521	regulatory associated protein of MTOR, complex 1	dendrite	Cellular component	-
MASP2	10747	mannan-binding lectin serine peptidase 2	peptidase activity	Molecular function	10946292
CEP135	9662	centrosomal protein 135kDa	protein binding	Molecular function	20531387
MVB12B	89853	multivesicular body subunit 12B	protein binding	Molecular function	18005716
OPHN1	4983	oligophrenin 1	axon guidance	Biological process	9582072
AQP2	359	aquaporin 2 (collecting duct)	ion transmembrane transport	Biological process	-
HSF4	3299	heat shock transcription factor 4	nucleoplasm	Cellular component	-
RPS6KB1	6198	ribosomal protein S6 kinase, 70kDa, polypeptide 1	negative regulation of insulin receptor signaling pathway	Biological process	18952604
CKS2	1164	CDC28 protein kinase regulatory subunit 2	regulation of cyclin-dependent protein serine/threonine kinase activity	Biological process	2227411
HDAC1	3065	histone deacetylase 1	odontogenesis of dentin-containing tooth	Biological process	-
SF1	7536	splicing factor 1	Leydig cell differentiation	Biological process	-
MEOX1	4222	mesenchyme homeobox 1	somite specification	Biological process	-
SLC6A18	348932	solute carrier family 6 (neutral amino acid transporter), member 18	amino acid transport	Biological process	-
CISD2	493856	CDGSH iron sulfur domain 2	endoplasmic reticulum	Cellular component	-
GPRIN1	114787	G protein regulated inducer of neurite outgrowth 1	neuron projection development	Biological process	-
TRIM24	8805	tripartite motif containing 24	transcription from RNA polymerase II promoter	Biological process	9115274
FNDC3A	22862	fibronectin type III domain containing 3A	membrane	Cellular component	19946888
MAPK1	5594	mitogen-activated protein kinase 1	innate immune response	Biological process	-
PTPN11	5781	protein tyrosine phosphatase, non-receptor type 11	regulation of interferon-gamma-mediated signaling pathway	Biological process	-
SLC26A9	115019	solute carrier family 26 (anion exchanger), member 9	positive regulation of gene expression	Biological process	20658517
WDR77	79084	WD repeat domain 77	methylosome	Cellular component	18984161
MAPKAPK3	7867	mitogen-activated protein kinase-activated protein kinase 3	activation of MAPK activity	Biological process	-
OMA1	115209	OMA1 zinc metallopeptidase	response to stress	Biological process	20038677
FZD8	8325	frizzled class receptor 8	G-protein coupled receptor signaling pathway	Biological process	-
CTDSP1	58190	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1	CTD phosphatase activity	Molecular function	12721286
OR4F17	81099	olfactory receptor, family 4, subfamily F, member 17	integral component of membrane	Cellular component	-
GSK3B	2932	glycogen synthase kinase 3 beta	cellular response to mechanical stimulus	Biological process	-
NFASC	23114	neurofascin	axon guidance	Biological process	-
CYB5D2	124936	cytochrome b5 domain containing 2	extracellular region	Cellular component	-
HIST1H4K	8362	histone cluster 1, H4k	CENP-A containing nucleosome assembly	Biological process	-
SHH	6469	sonic hedgehog	central nervous system development	Biological process	-
UPF3A	65110	UPF3 regulator of nonsense transcripts homolog A (yeast)	plasma membrane	Cellular component	-
KLHL40	131377	kelch-like family member 40	skeletal muscle fiber differentiation	Biological process	-
SLX4	84464	SLX4 structure-specific endonuclease subunit	cell junction	Cellular component	-
CLU	1191	clusterin	perinuclear region of cytoplasm	Cellular component	20068069
DPM1	8813	dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit	dolichol-phosphate-mannose synthase complex	Cellular component	10835346
NCKAP1L	3071	NCK-associated protein 1-like	positive regulation of B cell proliferation	Biological process	17875758
TEX40	25858	testis expressed 40	spermatogenesis	Biological process	-
PLA2G4F	255189	phospholipase A2, group IVF	glycerophospholipid biosynthetic process	Biological process	-
COL1A1	1277	collagen, type I, alpha 1	extracellular matrix structural constituent	Molecular function	-
CD48	962	CD48 molecule	defense response	Biological process	2828034
TMEM240	339453	transmembrane protein 240	synaptic membrane	Cellular component	-
CDHR1	92211	cadherin-related family member 1	integral component of plasma membrane	Cellular component	-
ADAM8	101	ADAM metallopeptidase domain 8	positive regulation of membrane protein ectodomain proteolysis	Biological process	15220135
FRK	2444	fyn-related Src family tyrosine kinase	nucleus	Cellular component	-
HIST1H2BF	8343	histone cluster 1, H2bf	protein heterodimerization activity	Molecular function	-
POLR2C	5432	polymerase (RNA) II (DNA directed) polypeptide C, 33kDa	piRNA metabolic process	Biological process	-
SRRM1	10250	serine/arginine repetitive matrix 1	transcription from RNA polymerase II promoter	Biological process	-
SERPINB4	6318	serpin peptidase inhibitor, clade B (ovalbumin), member 4	intracellular	Cellular component	21857942
CD2AP	23607	CD2-associated protein	regulation of actin cytoskeleton reorganization	Biological process	-
IL11	3589	interleukin 11	B cell differentiation	Biological process	2145578
PSMD14	10213	proteasome (prosome, macropain) 26S subunit, non-ATPase, 14	double-strand break repair via homologous recombination	Biological process	22909820
TRMT1	55621	tRNA methyltransferase 1 homolog (S. cerevisiae)	mitochondrion	Cellular component	-
BRINP1	1620	bone morphogenetic protein/retinoic acid inducible neural-specific 1	protein binding	Molecular function	12442002
GTF2I	2969	general transcription factor IIi	nucleoplasm	Cellular component	-
ITGB3	3690	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	melanosome	Cellular component	15466936
TMEM116	89894	transmembrane protein 116	biological_process	Biological process	-
VEGFA	7422	vascular endothelial growth factor A	nervous system development	Biological process	15351965
DERL1	79139	derlin 1	endoplasmic reticulum unfolded protein response	Biological process	15215856
IFNB1	3456	interferon, beta 1, fibroblast	positive regulation of peptidyl-serine phosphorylation of STAT protein	Biological process	18035482
WDR34	89891	WD repeat domain 34	protein binding	Molecular function	25416956
RC3H1	149041	ring finger and CCCH-type domains 1	negative regulation of germinal center formation	Biological process	-
BAG3	9531	BCL2-associated athanogene 3	cellular response to heat	Biological process	-
NDN	4692	necdin, melanoma antigen (MAGE) family member	axon extension	Biological process	-
VAV3	10451	vav 3 guanine nucleotide exchange factor	Fc-gamma receptor signaling pathway involved in phagocytosis	Biological process	-
KISS1R	84634	KISS1 receptor	positive regulation of hormone secretion	Biological process	-
A2M	2	alpha-2-macroglobulin	serine-type endopeptidase inhibitor activity	Molecular function	12538697
ANKH	56172	ANKH inorganic pyrophosphate transport regulator	inorganic diphosphate transport	Biological process	-
ST3GAL1	6482	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	keratan sulfate metabolic process	Biological process	-
NOXO1	124056	NADPH oxidase organizer 1	small GTPase mediated signal transduction	Biological process	-
SLC15A4	121260	solute carrier family 15 (oligopeptide transporter), member 4	ion transport	Biological process	-
CHUK	1147	conserved helix-loop-helix ubiquitous kinase	I-kappaB kinase/NF-kappaB signaling	Biological process	18626576
DNAJC3	5611	DnaJ (Hsp40) homolog, subfamily C, member 3	protein kinase inhibitor activity	Molecular function	7511204
ANAPC4	29945	anaphase promoting complex subunit 4	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	Biological process	-
RPL32	6161	ribosomal protein L32	SRP-dependent cotranslational protein targeting to membrane	Biological process	-
RBM24	221662	RNA binding motif protein 24	cytoplasm	Cellular component	-
CORO2A	7464	coronin, actin binding protein, 2A	actin cytoskeleton organization	Biological process	-
MT3	4504	metallothionein 3	cell proliferation	Biological process	1873033
MED6	10001	mediator complex subunit 6	RNA polymerase II transcription cofactor activity	Molecular function	-
NPC2	10577	Niemann-Pick disease, type C2	cholesterol transport	Biological process	17018531
RAE1	8480	ribonucleic acid export 1	regulation of cellular response to heat	Biological process	-
CYP2E1	1571	cytochrome P450, family 2, subfamily E, polypeptide 1	heterocycle metabolic process	Biological process	19651758
PNLIPRP2	5408	pancreatic lipase-related protein 2	small molecule metabolic process	Biological process	-
METTL16	79066	methyltransferase like 16	rRNA base methylation	Biological process	-
SMARCA4	6597	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	negative regulation of transcription, DNA-templated	Biological process	18487222
ADAM11	4185	ADAM metallopeptidase domain 11	metalloendopeptidase activity	Molecular function	-
F5	2153	coagulation factor V (proaccelerin, labile factor)	serine-type endopeptidase activity	Molecular function	-
TFRC	7037	transferrin receptor	endosome	Cellular component	14612438
SLC35E3	55508	solute carrier family 35, member E3	antiporter activity	Molecular function	-
POLR2C	5432	polymerase (RNA) II (DNA directed) polypeptide C, 33kDa	transcription elongation from RNA polymerase II promoter	Biological process	-
DGAT2	84649	diacylglycerol O-acyltransferase 2	cellular response to oleic acid	Biological process	-
BRCA1	672	breast cancer 1, early onset	regulation of transcription from RNA polymerase III promoter	Biological process	10918303
KIF2A	3796	kinesin heavy chain member 2A	antigen processing and presentation of exogenous peptide antigen via MHC class II	Biological process	-
GATA4	2626	GATA binding protein 4	blood coagulation	Biological process	-
WWC1	23286	WW and C2 domain containing 1	negative regulation of organ growth	Biological process	24682284
ASGR2	433	asialoglycoprotein receptor 2	receptor-mediated endocytosis	Biological process	3863106
ABCG1	9619	ATP-binding cassette, sub-family G (WHITE), member 1	external side of plasma membrane	Cellular component	16556852
RPE	6120	ribulose-5-phosphate-3-epimerase	extracellular exosome	Cellular component	23533145
POLR2C	5432	polymerase (RNA) II (DNA directed) polypeptide C, 33kDa	DNA repair	Biological process	-
NDUFAB1	4706	NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa	calcium ion binding	Molecular function	10234612
MYOF	26509	myoferlin	protein binding	Molecular function	17185750
OPN1LW	5956	opsin 1 (cone pigments), long-wave-sensitive	phototransduction, visible light	Biological process	-
MVD	4597	mevalonate (diphospho) decarboxylase	protein N-linked glycosylation via asparagine	Biological process	-
FLRT2	23768	fibronectin leucine rich transmembrane protein 2	integral component of plasma membrane	Cellular component	10644439
DNA2	1763	DNA replication helicase/nuclease 2	DNA duplex unwinding	Biological process	16595800
BCL2L1	598	BCL2-like 1	protein homodimerization activity	Molecular function	-
NKX1-1	54729	NK1 homeobox 1	lipid metabolic process	Biological process	-
PSMC2	5701	proteasome (prosome, macropain) 26S subunit, ATPase, 2	regulation of cellular amino acid metabolic process	Biological process	-
POLR1D	51082	polymerase (RNA) I polypeptide D, 16kDa	protein dimerization activity	Molecular function	-
PLA2G7	7941	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	low-density lipoprotein particle remodeling	Biological process	8624782
MBP	4155	myelin basic protein	response to tumor necrosis factor	Biological process	-
MAP2K5	5607	mitogen-activated protein kinase kinase 5	ERK5 cascade	Biological process	-
ZNF645	158506	zinc finger protein 645	ligase activity	Molecular function	-
OSMR	9180	oncostatin M receptor	response to cytokine	Biological process	8999038
CPSF7	79869	cleavage and polyadenylation specific factor 7, 59kDa	nucleus	Cellular component	20695905
DAAM2	23500	dishevelled associated activator of morphogenesis 2	Rho GTPase binding	Molecular function	-
FSHB	2488	follicle stimulating hormone, beta polypeptide	progesterone biosynthetic process	Biological process	14557487
UNC5CL	222643	unc-5 homolog C (C. elegans)-like	membrane	Cellular component	22158417
SNAP47	116841	synaptosomal-associated protein, 47kDa	plasma membrane	Cellular component	-
RFX6	222546	regulatory factor X, 6	pancreatic A cell differentiation	Biological process	-
ARPC3	10094	actin related protein 2/3 complex, subunit 3, 21kDa	ephrin receptor signaling pathway	Biological process	-
SIK1	150094	salt-inducible kinase 1	regulation of mitotic cell cycle	Biological process	-
APOO	79135	apolipoprotein O	lipid transport	Biological process	-
GDPD5	81544	glycerophosphodiester phosphodiesterase domain containing 5	perinuclear region of cytoplasm	Cellular component	-
SLC26A3	1811	solute carrier family 26 (anion exchanger), member 3	bicarbonate transmembrane transporter activity	Molecular function	-
CDK5RAP3	80279	CDK5 regulatory subunit associated protein 3	NF-kappaB binding	Molecular function	17785205
UNC13D	201294	unc-13 homolog D (C. elegans)	membrane	Cellular component	-
TET3	200424	tet methylcytosine dioxygenase 3	female pronucleus	Cellular component	-
OR2C3	81472	olfactory receptor, family 2, subfamily C, member 3	sensory perception of smell	Biological process	-
E2F7	144455	E2F transcription factor 7	positive regulation of DNA endoreduplication	Biological process	-
MYH10	4628	myosin, heavy chain 10, non-muscle	adult heart development	Biological process	-
TCEB1	6921	transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)	protein binding	Molecular function	10205047
PPP3R1	5534	protein phosphatase 3, regulatory subunit B, alpha	calcium ion binding	Molecular function	2558868
ASB14	142686	ankyrin repeat and SOCS box containing 14	protein ubiquitination	Biological process	-
GCGR	2642	glucagon receptor	adenylate cyclase-modulating G-protein coupled receptor signaling pathway	Biological process	9287038
TOR2A	27433	torsin family 2, member A	extracellular region	Cellular component	-
PSMB1	5689	proteasome (prosome, macropain) subunit, beta type, 1	negative regulation of apoptotic process	Biological process	-
MRPL9	65005	mitochondrial ribosomal protein L9	mitochondrial inner membrane	Cellular component	-
HIF1A	3091	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	regulation of gene expression	Biological process	18419598
PCGF2	7703	polycomb group ring finger 2	PRC1 complex	Cellular component	19636380
CSF1R	1436	colony stimulating factor 1 receptor	osteoclast differentiation	Biological process	-
RPS6KA5	9252	ribosomal protein S6 kinase, 90kDa, polypeptide 5	positive regulation of histone acetylation	Biological process	20018936
RPS6KB1	6198	ribosomal protein S6 kinase, 70kDa, polypeptide 1	response to lipopolysaccharide	Biological process	-
SYNCRIP	10492	synaptotagmin binding, cytoplasmic RNA interacting protein	endoplasmic reticulum	Cellular component	-
PUM2	23369	pumilio RNA-binding family member 2	cytoplasm	Cellular component	-
SLC6A19	340024	solute carrier family 6 (neutral amino acid transporter), member 19	neurotransmitter:sodium symporter activity	Molecular function	-
TACR1	6869	tachykinin receptor 1	positive regulation of renal sodium excretion	Biological process	-
ELOVL3	83401	ELOVL fatty acid elongase 3	fatty acid elongation, monounsaturated fatty acid	Biological process	20937905
NPR2	4882	natriuretic peptide receptor 2	peptide hormone binding	Molecular function	-
ERCC8	1161	excision repair cross-complementation group 8	response to oxidative stress	Biological process	17297471
STAT1	6772	signal transducer and activator of transcription 1, 91kDa	cellular response to interferon-beta	Biological process	18035482
GALNT3	2591	polypeptide N-acetylgalactosaminyltransferase 3	carbohydrate metabolic process	Biological process	9592121
RECQL	5965	RecQ helicase-like	protein binding	Molecular function	15886194
OSTF1	26578	osteoclast stimulating factor 1	ossification	Biological process	10092216
EZH2	2146	enhancer of zeste 2 polycomb repressive complex 2 subunit	nucleoplasm	Cellular component	-
HOMER1	9456	homer scaffolding protein 1	axon	Cellular component	-
SDF2	6388	stromal cell-derived factor 2	protein O-linked mannosylation	Biological process	8918255
STRA6	64220	stimulated by retinoic acid 6	adrenal gland development	Biological process	17273977
ARL2	402	ADP-ribosylation factor-like 2	energy reserve metabolic process	Biological process	-
CHML	1122	choroideremia-like (Rab escort protein 2)	nucleoplasm	Cellular component	-
TNFSF4	7292	tumor necrosis factor (ligand) superfamily, member 4	positive regulation of interleukin-2 production	Biological process	-
PSMA5	5686	proteasome (prosome, macropain) subunit, alpha type, 5	nucleus	Cellular component	21630459
SSBP3-AS1	619518	SSBP3 antisense RNA 1	extracellular region	Cellular component	-
ACVR2B	93	activin A receptor, type IIB	odontogenesis of dentin-containing tooth	Biological process	-
METTL21A	151194	methyltransferase like 21A	protein binding	Molecular function	23921388
KRT36	8689	keratin 36, type I	extracellular exosome	Cellular component	23533145
DDX56	54606	DEAD (Asp-Glu-Ala-Asp) box helicase 56	membrane	Cellular component	19946888
PIKFYVE	200576	phosphoinositide kinase, FYVE finger containing	cell-cell junction	Cellular component	-
SVOP	55530	SV2 related protein homolog (rat)	synaptic vesicle	Cellular component	-
GYS2	2998	glycogen synthase 2 (liver)	cytosol	Cellular component	-
KRBA2	124751	KRAB-A domain containing 2	DNA integration	Biological process	-
AK3	50808	adenylate kinase 3	protein binding	Molecular function	25416956
NID1	4811	nidogen 1	extracellular region	Cellular component	-
AKR1D1	6718	aldo-keto reductase family 1, member D1	small molecule metabolic process	Biological process	-
ADIRF	10974	adipogenesis regulatory factor	positive regulation of transcription from RNA polymerase II promoter	Biological process	23239344
AKT1	207	v-akt murine thymoma viral oncogene homolog 1	glycogen cell differentiation involved in embryonic placenta development	Biological process	-
CD38	952	CD38 molecule	signal transduction	Biological process	8253715
RPL41	6171	ribosomal protein L41	gene expression	Biological process	-
ATP9A	10079	ATPase, class II, type 9A	magnesium ion binding	Molecular function	-
VAMP5	10791	vesicle-associated membrane protein 5	protein binding	Molecular function	25416956
FLCN	201163	folliculin	negative regulation of TOR signaling	Biological process	-
FSD1	79187	fibronectin type III and SPRY domain containing 1	microtubule	Cellular component	-
BLM	641	Bloom syndrome, RecQ helicase-like	ATP-dependent helicase activity	Molecular function	12818200
MCEE	84693	methylmalonyl CoA epimerase	short-chain fatty acid catabolic process	Biological process	-
CATSPER2	117155	cation channel, sperm associated 2	plasma membrane	Cellular component	-
HIF1AN	55662	hypoxia inducible factor 1, alpha subunit inhibitor	NF-kappaB binding	Molecular function	17003112
SOAT1	6646	sterol O-acyltransferase 1	cholesterol storage	Biological process	8407899
MAP3K7	6885	mitogen-activated protein kinase kinase kinase 7	activation of NF-kappaB-inducing kinase activity	Biological process	10094049
EBP	10682	emopamil binding protein (sterol isomerase)	hemopoiesis	Biological process	-
AKAP1	8165	A kinase (PRKA) anchor protein 1	mitochondrial outer membrane	Cellular component	-
TRIT1	54802	tRNA isopentenyltransferase 1	metal ion binding	Molecular function	-
FPGS	2356	folylpolyglutamate synthase	mitochondrial matrix	Cellular component	-
WDPCP	51057	WD repeat containing planar cell polarity effector	regulation of embryonic cell shape	Biological process	-
FHIT	2272	fragile histidine triad	bis(5'-adenosyl)-triphosphatase activity	Molecular function	8794732
QARS	5859	glutaminyl-tRNA synthetase	brain development	Biological process	24656866
SORT1	6272	sortilin 1	Golgi cisterna membrane	Cellular component	-
ZBTB40	9923	zinc finger and BTB domain containing 40	regulation of transcription, DNA-templated	Biological process	-
HPGD	3248	hydroxyprostaglandin dehydrogenase 15-(NAD)	basolateral plasma membrane	Cellular component	-
NOL3	8996	nucleolar protein 3 (apoptosis repressor with CARD domain)	nucleolus	Cellular component	-
IDO2	169355	indoleamine 2,3-dioxygenase 2	indoleamine 2,3-dioxygenase activity	Molecular function	17499941
DRD3	1814	dopamine receptor D3	apical part of cell	Cellular component	-
TULP3	7289	tubby like protein 3	phosphatidylinositol-4,5-bisphosphate binding	Molecular function	11375483
ACOT2	10965	acyl-CoA thioesterase 2	carboxylic ester hydrolase activity	Molecular function	-
TNFRSF1B	7133	tumor necrosis factor receptor superfamily, member 1B	plasma membrane	Cellular component	-
MTIF3	219402	mitochondrial translational initiation factor 3	ribosome disassembly	Biological process	12095986
C19orf80	55908	chromosome 19 open reading frame 80	cell maturation	Biological process	-
KCNE2	9992	potassium channel, voltage gated subfamily E regulatory beta subunit 2	cellular response to drug	Biological process	10219239
SKA3	221150	spindle and kinetochore associated complex subunit 3	cytoplasm	Cellular component	-
MTO1	25821	mitochondrial tRNA translation optimization 1	mitochondrion	Cellular component	-
ING3	54556	inhibitor of growth family, member 3	transcription, DNA-templated	Biological process	-
ACSS1	84532	acyl-CoA synthetase short-chain family member 1	protein binding	Molecular function	16788062
UQCRC1	7384	ubiquinol-cytochrome c reductase core protein I	small molecule metabolic process	Biological process	-
ADD3	120	adducin 3 (gamma)	structural constituent of cytoskeleton	Molecular function	8893809
FNTB	2342	farnesyltransferase, CAAX box, beta	protein farnesylation	Biological process	16893176
NRARP	441478	NOTCH-regulated ankyrin repeat protein	negative regulation of T cell differentiation	Biological process	-
OXCT1	5019	3-oxoacid CoA transferase 1	response to nutrient	Biological process	-
BAHD1	22893	bromo adjacent homology domain containing 1	chromatin silencing	Biological process	-
SLC2A2	6514	solute carrier family 2 (facilitated glucose transporter), member 2	cytoplasm	Cellular component	-
KDM2B	84678	lysine (K)-specific demethylase 2B	embryonic camera-type eye morphogenesis	Biological process	-
FAM9C	171484	family with sequence similarity 9, member C	nucleus	Cellular component	-
DVL2	1856	dishevelled segment polarity protein 2	heart development	Biological process	-
RPL7A	6130	ribosomal protein L7a	translational initiation	Biological process	-
CIDEA	1149	cell death-inducing DFFA-like effector a	negative regulation of tumor necrosis factor production	Biological process	15919794
HTRA2	27429	HtrA serine peptidase 2	cytoplasmic side of plasma membrane	Cellular component	-
ENTPD6	955	ectonucleoside triphosphate diphosphohydrolase 6 (putative)	integral component of membrane	Cellular component	-
PINK1	65018	PTEN induced putative kinase 1	negative regulation of mitochondrial fission	Biological process	19279012
LHX1	3975	LIM homeobox 1	embryonic pattern specification	Biological process	-
SCP2	6342	sterol carrier protein 2	phospholipid transport	Biological process	12641450
PPIH	10465	peptidylprolyl isomerase H (cyclophilin H)	U4/U6 snRNP	Cellular component	9570313
JUP	3728	junction plakoglobin	desmosome	Cellular component	1639850
IL26	55801	interleukin 26	immune response	Biological process	-
ADAM17	6868	ADAM metallopeptidase domain 17	positive regulation of protein phosphorylation	Biological process	18625725
EP300	2033	E1A binding protein p300	mitotic cell cycle	Biological process	-
EXOSC9	5393	exosome component 9	nuclear-transcribed mRNA catabolic process	Biological process	17545563
HTR1F	3355	5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	Biological process	8380639
RAET1E	135250	retinoic acid early transcript 1E	natural killer cell mediated cytotoxicity	Biological process	15240696
ALPP	250	alkaline phosphatase, placental	anchored component of membrane	Cellular component	-
TYK2	7297	tyrosine kinase 2	extracellular exosome	Cellular component	20458337
CAV1	857	caveolin 1, caveolae protein, 22kDa	protein homooligomerization	Biological process	-
PANK1	53354	pantothenate kinase 1	small molecule metabolic process	Biological process	-
IFNA21	3452	interferon, alpha 21	defense response to virus	Biological process	-
RANBP2	5903	RAN binding protein 2	hexose transport	Biological process	-
STK24	8428	serine/threonine kinase 24	metal ion binding	Molecular function	-
IFNL1	282618	interferon, lambda 1	negative regulation of memory T cell differentiation	Biological process	19346497
EGFL7	51162	EGF-like-domain, multiple 7	negative regulation of Notch signaling pathway	Biological process	20947685
CPOX	1371	coproporphyrinogen oxidase	response to arsenic-containing substance	Biological process	-
SART3	9733	squamous cell carcinoma antigen recognized by T cells 3	U4 snRNA binding	Molecular function	15314151
DIS3L	115752	DIS3 like exosome 3'-5' exoribonuclease	3'-5'-exoribonuclease activity	Molecular function	20531386
TUBB	203068	tubulin, beta class I	cytoskeleton-dependent intracellular transport	Biological process	12090300
GRM6	2916	glutamate receptor, metabotropic 6	protein homodimerization activity	Molecular function	17405131
HERC1	8925	HECT and RLD domain containing E3 ubiquitin protein ligase family member 1	neuromuscular process controlling balance	Biological process	-
ZP3	7784	zona pellucida glycoprotein 3 (sperm receptor)	protein binding	Molecular function	19945174
AQP9	366	aquaporin 9	urea transmembrane transporter activity	Molecular function	-
EIF3E	3646	eukaryotic translation initiation factor 3, subunit E	nucleus	Cellular component	-
FOXC2	2303	forkhead box C2	regulation of organ growth	Biological process	-
FUT8	2530	fucosyltransferase 8 (alpha (1,6) fucosyltransferase)	Golgi apparatus	Cellular component	11698403
KCNAB2	8514	potassium channel, voltage gated subfamily A regulatory beta subunit 2	NADPH oxidation	Biological process	-
CDC42BPB	9578	CDC42 binding protein kinase beta (DMPK-like)	cytoskeleton organization	Biological process	9418861
CTNNA1	1495	catenin (cadherin-associated protein), alpha 1, 102kDa	cellular response to indole-3-methanol	Biological process	10868478
RSAD2	91543	radical S-adenosyl methionine domain containing 2	cytokine-mediated signaling pathway	Biological process	-
RANGRF	29098	RAN guanine nucleotide release factor	protein exit from endoplasmic reticulum	Biological process	23420830
VEGFC	7424	vascular endothelial growth factor C	positive regulation of blood vessel endothelial cell migration	Biological process	-
MKX	283078	mohawk homeobox	positive regulation of collagen biosynthetic process	Biological process	-
MMP17	4326	matrix metallopeptidase 17 (membrane-inserted)	zinc ion binding	Molecular function	-
ZNF676	163223	zinc finger protein 676	regulation of transcription, DNA-templated	Biological process	-
CASP5	838	caspase 5, apoptosis-related cysteine peptidase	cytoplasm	Cellular component	-
SEMA7A	8482	semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)	regulation of inflammatory response	Biological process	-
SNX1	6642	sorting nexin 1	phosphatidylinositol binding	Molecular function	15498486
MED29	55588	mediator complex subunit 29	mediator complex	Cellular component	14638676
WDR48	57599	WD repeat domain 48	skin development	Biological process	-
ATCAY	85300	ataxia, cerebellar, Cayman type	cytoplasm	Cellular component	16899818
AFM	173	afamin	blood microparticle	Cellular component	22516433
IFI30	10437	interferon, gamma-inducible protein 30	intracellular membrane-bounded organelle	Cellular component	-
PRKCSH	5589	protein kinase C substrate 80K-H	endoplasmic reticulum lumen	Cellular component	-
VAMP8	8673	vesicle-associated membrane protein 8	mucus secretion	Biological process	22144578
ZNF785	146540	zinc finger protein 785	nucleus	Cellular component	-
ARL8B	55207	ADP-ribosylation factor-like 8B	spindle midzone	Cellular component	15331635
NTRK2	4915	neurotrophic tyrosine kinase, receptor, type 2	peptidyl-tyrosine phosphorylation	Biological process	-
FGFR2	2263	fibroblast growth factor receptor 2	ventricular cardiac muscle tissue morphogenesis	Biological process	-
ZFPM2	23414	zinc finger protein, FOG family member 2	negative regulation of fat cell differentiation	Biological process	20705609
RPL31	6160	ribosomal protein L31	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Biological process	-
FGR	2268	FGR proto-oncogene, Src family tyrosine kinase	regulation of protein kinase activity	Biological process	-
DDAH2	23564	dimethylarginine dimethylaminohydrolase 2	positive regulation of nitric oxide biosynthetic process	Biological process	-
CASP3	836	caspase 3, apoptosis-related cysteine peptidase	cytoplasm	Cellular component	-
DUSP4	1846	dual specificity phosphatase 4	inactivation of MAPK activity	Biological process	-
TOM1L2	146691	target of myb1-like 2 (chicken)	negative regulation of mitotic nuclear division	Biological process	16479011
TRAF4	9618	TNF receptor-associated factor 4	cytoskeleton	Cellular component	-
NLRP2	55655	NLR family, pyrin domain containing 2	positive regulation of interleukin-1 beta secretion	Biological process	15030775
ORC1	4998	origin recognition complex, subunit 1	nucleus	Cellular component	-
GSTP1	2950	glutathione S-transferase pi 1	negative regulation of apoptotic process	Biological process	16130169
FREM3	166752	FRAS1 related extracellular matrix 3	cell communication	Biological process	-
GRM5	2915	glutamate receptor, metabotropic 5	postsynaptic density	Cellular component	-
HDAC2	3066	histone deacetylase 2	positive regulation of oligodendrocyte differentiation	Biological process	-
PSMD11	5717	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	proteasome complex	Cellular component	17323924
CD151	977	CD151 molecule (Raph blood group)	protein binding	Molecular function	14676841
PDE2A	5138	phosphodiesterase 2A, cGMP-stimulated	nucleus	Cellular component	10375378
CR2	1380	complement component (3d/Epstein Barr virus) receptor 2	complement activation, classical pathway	Biological process	-
STRADA	92335	STE20-related kinase adaptor alpha	insulin receptor signaling pathway	Biological process	-
ADGRE2	30817	adhesion G protein-coupled receptor E2	inflammatory response	Biological process	-
SSH1	54434	slingshot protein phosphatase 1	cell morphogenesis	Biological process	14645219
VAT1L	57687	vesicle amine transport 1-like	oxidation-reduction process	Biological process	-
OR56A4	120793	olfactory receptor, family 56, subfamily A, member 4	beta-adrenergic receptor activity	Molecular function	-
DDX1	1653	DEAD (Asp-Glu-Ala-Asp) box helicase 1	spliceosomal complex assembly	Biological process	7689221
GRB7	2886	growth factor receptor-bound protein 7	phosphatidylinositol binding	Molecular function	12021278
MTFR1	9650	mitochondrial fission regulator 1	mitochondrion organization	Biological process	-
NUDT1	4521	nudix (nucleoside diphosphate linked moiety X)-type motif 1	purine nucleotide catabolic process	Biological process	10608900
PLAU	5328	plasminogen activator, urokinase	regulation of cell adhesion mediated by integrin	Biological process	8837777
CDH2	1000	cadherin 2, type 1, N-cadherin (neuronal)	cell-cell adherens junction	Cellular component	19101069
GCH1	2643	GTP cyclohydrolase 1	response to pain	Biological process	-
RYK	6259	receptor-like tyrosine kinase	axon guidance	Biological process	-
DET1	55070	de-etiolated homolog 1 (Arabidopsis)	nucleus	Cellular component	-
BCL2L1	598	BCL2-like 1	regulation of mitochondrial membrane potential	Biological process	9843949
ITLN1	55600	intelectin 1 (galactofuranose binding)	membrane raft	Cellular component	-
SVIP	258010	small VCP/p97-interacting protein	extracellular exosome	Cellular component	20458337
PSMB5	5693	proteasome (prosome, macropain) subunit, beta type, 5	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	Biological process	-
XK	7504	X-linked Kx blood group	cell	Cellular component	-
IGHG3	3502	immunoglobulin heavy constant gamma 3 (G3m marker)	complement activation	Biological process	-
ERCC5	2073	excision repair cross-complementation group 5	nucleoplasm	Cellular component	-
CA9	768	carbonic anhydrase IX	basolateral plasma membrane	Cellular component	-
ZBTB16	7704	zinc finger and BTB domain containing 16	anterior/posterior pattern specification	Biological process	-
GNA15	2769	guanine nucleotide binding protein (G protein), alpha 15 (Gq class)	phospholipase C-activating dopamine receptor signaling pathway	Biological process	-
KCNS2	3788	potassium voltage-gated channel, modifier subfamily S, member 2	delayed rectifier potassium channel activity	Molecular function	-
NT5C3A	51251	5'-nucleotidase, cytosolic IIIA	pyrimidine nucleobase metabolic process	Biological process	-
PPARGC1A	10891	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	negative regulation of receptor activity	Biological process	-
EIF5A	1984	eukaryotic translation initiation factor 5A	nuclear pore	Cellular component	10381392
KPRP	448834	keratinocyte proline-rich protein	cytoplasm	Cellular component	-
IRAK4	51135	interleukin-1 receptor-associated kinase 4	cytoplasm	Cellular component	-
TXNDC2	84203	thioredoxin domain containing 2 (spermatozoa)	nucleus	Cellular component	-
FAM63B	54629	family with sequence similarity 63, member B	nucleoplasm	Cellular component	-
CRY2	1408	cryptochrome circadian clock 2	DNA binding	Molecular function	12627958
CHGB	1114	chromogranin B	hormone activity	Molecular function	3608978
BTK	695	Bruton agammaglobulinemia tyrosine kinase	perinuclear region of cytoplasm	Cellular component	-
WIBG	84305	within bgcn homolog (Drosophila)	poly(A) RNA binding	Molecular function	22681889
SKIL	6498	SKI-like proto-oncogene	negative regulation of cell differentiation	Biological process	-
NSUN2	54888	NOP2/Sun RNA methyltransferase family, member 2	nucleolus	Cellular component	17071714
ZNF514	84874	zinc finger protein 514	metal ion binding	Molecular function	-
DERL2	51009	derlin 2	ER-associated ubiquitin-dependent protein catabolic process	Biological process	16449189
TNN	63923	tenascin N	proteinaceous extracellular matrix	Cellular component	-
CREBL2	1389	cAMP responsive element binding protein-like 2	positive regulation of fat cell differentiation	Biological process	-
OR9Q1	219956	olfactory receptor, family 9, subfamily Q, member 1	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
COL9A3	1299	collagen, type IX, alpha 3	collagen type IX trimer	Cellular component	8660302
PRMT2	3275	protein arginine methyltransferase 2	progesterone receptor binding	Molecular function	12039952
MEF2A	4205	myocyte enhancer factor 2A	RNA polymerase II transcription factor binding	Molecular function	15466416
UBA1	7317	ubiquitin-like modifier activating enzyme 1	lysosomal membrane	Cellular component	1376922
NCOA1	8648	nuclear receptor coactivator 1	male gonad development	Biological process	-
TCF7L1	83439	transcription factor 7-like 1 (T-cell specific, HMG-box)	generation of neurons	Biological process	-
MMP12	4321	matrix metallopeptidase 12	wound healing, spreading of epidermal cells	Biological process	15802269
POLR2D	5433	polymerase (RNA) II (DNA directed) polypeptide D	transcription from RNA polymerase II promoter	Biological process	-
LILRA2	11027	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2	extracellular region	Cellular component	-
ZNF410	57862	zinc finger protein 410	protein binding	Molecular function	25416956
ADAMTSL5	339366	ADAMTS-like 5	microfibril	Cellular component	23010571
CD101	9398	CD101 molecule	integral component of membrane	Cellular component	-
IGF1R	3480	insulin-like growth factor 1 receptor	insulin receptor binding	Molecular function	8452530
AKT1	207	v-akt murine thymoma viral oncogene homolog 1	glucose transport	Biological process	-
PROSC	11212	proline synthetase co-transcribed homolog (bacterial)	extracellular exosome	Cellular component	23376485
CCL7	6354	chemokine (C-C motif) ligand 7	signal transduction	Biological process	10201901
PTPRJ	5795	protein tyrosine phosphatase, receptor type, J	nucleoplasm	Cellular component	-
FAIM2	23017	Fas apoptotic inhibitory molecule 2	cerebellar Purkinje cell differentiation	Biological process	-
APC	324	adenomatous polyposis coli	positive regulation of pseudopodium assembly	Biological process	17192415
OR10J5	127385	olfactory receptor, family 10, subfamily J, member 5	integral component of membrane	Cellular component	-
MZT2A	653784	mitotic spindle organizing protein 2A	centrosome	Cellular component	-
LCK	3932	LCK proto-oncogene, Src family tyrosine kinase	positive regulation of T cell receptor signaling pathway	Biological process	12614355
TTC26	79989	tetratricopeptide repeat domain 26	intraciliary transport	Biological process	-
OR4L1	122742	olfactory receptor, family 4, subfamily L, member 1	integral component of membrane	Cellular component	-
FXN	2395	frataxin	negative regulation of release of cytochrome c from mitochondria	Biological process	16608849
EGF	1950	epidermal growth factor	negative regulation of cholesterol efflux	Biological process	-
ADAM9	8754	ADAM metallopeptidase domain 9	cellular response to lipopolysaccharide	Biological process	22480688
NLRC4	58484	NLR family, CARD domain containing 4	magnesium ion binding	Molecular function	15882992
RTN4R	65078	reticulon 4 receptor	receptor activity	Molecular function	11201742
HIGD1A	25994	HIG1 hypoxia inducible domain family, member 1A	oxidation-reduction process	Biological process	-
UBB	7314	ubiquitin B	cytokine-mediated signaling pathway	Biological process	-
SHH	6469	sonic hedgehog	positive regulation of ureter smooth muscle cell differentiation	Biological process	-
ECM1	1893	extracellular matrix protein 1	protease binding	Molecular function	16512877
POT1	25913	protection of telomeres 1	positive regulation of telomerase activity	Biological process	16043710
SIX6	4990	SIX homeobox 6	visual perception	Biological process	10512683
TFAM	7019	transcription factor A, mitochondrial	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	22037171
FOXA2	3170	forkhead box A2	regulation of steroid metabolic process	Biological process	-
MGAT4C	25834	MGAT4 family, member C	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity	Molecular function	-
ADGRB1	575	adhesion G protein-coupled receptor B1	peripheral nervous system development	Biological process	10343108
SP1	6667	Sp1 transcription factor	cytoplasm	Cellular component	-
ADORA2B	136	adenosine A2b receptor	plasma membrane	Cellular component	-
RAB8A	4218	RAB8A, member RAS oncogene family	phagocytic vesicle	Cellular component	21255211
OPRK1	4986	opioid receptor, kappa 1	adenylate cyclase-inhibiting opioid receptor signaling pathway	Biological process	22437504
MIF	4282	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	extracellular region	Cellular component	12782713
UBC	7316	ubiquitin C	endosomal transport	Biological process	-
EDNRA	1909	endothelin receptor type A	heart development	Biological process	-
SUV39H2	79723	suppressor of variegation 3-9 homolog 2 (Drosophila)	chromatin binding	Molecular function	-
SSR2	6746	signal sequence receptor, beta (translocon-associated protein beta)	integral component of membrane	Cellular component	-
FXR1	8087	fragile X mental retardation, autosomal homolog 1	polysome	Cellular component	-
BET1L	51272	Bet1 golgi vesicular membrane trafficking protein-like	retrograde transport, endosome to Golgi	Biological process	15215310
PMAIP1	5366	phorbol-12-myristate-13-acetate-induced protein 1	defense response to virus	Biological process	15705586
PFN1	5216	profilin 1	cytoplasm	Cellular component	24700464
TGFBR2	7048	transforming growth factor, beta receptor II (70/80kDa)	gastrulation	Biological process	-
UBN2	254048	ubinuclein 2	sequence-specific DNA binding transcription factor activity	Molecular function	-
MRLN	100507027	myoregulin	negative regulation of calcium ion import into sarcoplasmic reticulum	Biological process	-
TXNDC8	255220	thioredoxin domain containing 8 (spermatozoa)	oxidation-reduction process	Biological process	-
DDR1	780	discoidin domain receptor tyrosine kinase 1	protein autophosphorylation	Biological process	9659899
ELANE	1991	elastase, neutrophil expressed	proteolysis	Biological process	11907569
PDK2	5164	pyruvate dehydrogenase kinase, isozyme 2	intrinsic apoptotic signaling pathway by p53 class mediator	Biological process	22123926
TH	7054	tyrosine hydroxylase	dopamine biosynthetic process from tyrosine	Biological process	10907721
HSPE1	3336	heat shock 10kDa protein 1	unfolded protein binding	Molecular function	12483302
KISS1R	84634	KISS1 receptor	protein binding	Molecular function	11387329
WDTC1	23038	WD and tetratricopeptide repeats 1	enzyme inhibitor activity	Molecular function	-
HDAC3	8841	histone deacetylase 3	cytoplasm	Cellular component	12711221
FASLG	356	Fas ligand (TNF superfamily, member 6)	caveola	Cellular component	-
CNR1	1268	cannabinoid receptor 1 (brain)	positive regulation of blood pressure	Biological process	-
IDO1	3620	indoleamine 2,3-dioxygenase 1	swimming behavior	Biological process	-
ARID4B	51742	AT rich interactive domain 4B (RBP1-like)	establishment of Sertoli cell barrier	Biological process	-
INO80	54617	INO80 complex subunit	chromatin remodeling	Biological process	16298340
RPL24	6152	ribosomal protein L24	viral life cycle	Biological process	-
H3F3B	3021	H3 histone, family 3B (H3.3B)	protein binding	Molecular function	19494831
PPARA	5465	peroxisome proliferator-activated receptor alpha	lipid binding	Molecular function	12955147
ALK	238	anaplastic lymphoma receptor tyrosine kinase	regulation of apoptotic process	Biological process	19459784
UGT2A1	10941	UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus	flavonoid glucuronidation	Biological process	-
PYGO2	90780	pygopus family PHD finger 2	nucleoplasm	Cellular component	-
CACNA1A	773	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	negative regulation of hormone biosynthetic process	Biological process	-
PEX16	9409	peroxisomal biogenesis factor 16	membrane	Cellular component	19946888
VPS52	6293	vacuolar protein sorting 52 homolog (S. cerevisiae)	Golgi apparatus	Cellular component	15878329
IFIT5	24138	interferon-induced protein with tetratricopeptide repeats 5	apical part of cell	Cellular component	23317505
ID3	3399	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	metanephros development	Biological process	-
ABR	29	active BCR-related	membrane	Cellular component	19946888
ERBB2	2064	erb-b2 receptor tyrosine kinase 2	protein tyrosine kinase activity	Molecular function	-
MIB1	57534	mindbomb E3 ubiquitin protein ligase 1	somitogenesis	Biological process	-
KCNA5	3741	potassium channel, voltage gated shaker related subfamily A, member 5	receptor binding	Molecular function	-
ITPA	3704	inosine triphosphatase (nucleoside triphosphate pyrophosphatase)	XTP diphosphatase activity	Molecular function	-
VEGFB	7423	vascular endothelial growth factor B	protein binding	Molecular function	11122379
VPS4B	9525	vacuolar protein sorting 4 homolog B (S. cerevisiae)	protein C-terminus binding	Molecular function	17928862
ITGB1BP2	26548	integrin beta 1 binding protein (melusin) 2	integrin binding	Molecular function	-
RPLP0	6175	ribosomal protein, large, P0	viral process	Biological process	-
GNAI2	2771	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	GTPase activity	Molecular function	-
SETMAR	6419	SET domain and mariner transposase fusion gene	protein binding	Molecular function	19390626
CASP3	836	caspase 3, apoptosis-related cysteine peptidase	cysteine-type endopeptidase activity involved in apoptotic process	Molecular function	10921886
SMAD3	4088	SMAD family member 3	transport	Biological process	15799969
USP17L2	377630	ubiquitin specific peptidase 17-like family member 2	negative regulation of GTPase activity	Biological process	19188362
LGALS3BP	3959	lectin, galactoside-binding, soluble, 3 binding protein	cell adhesion	Biological process	-
TTF1	7270	transcription termination factor, RNA polymerase I	nucleolus	Cellular component	-
TNRC6B	23112	trinucleotide repeat containing 6B	posttranscriptional gene silencing	Biological process	-
GJB7	375519	gap junction protein, beta 7, 25kDa	integral component of membrane	Cellular component	-
TRMT11	60487	tRNA methyltransferase 11 homolog (S. cerevisiae)	tRNA processing	Biological process	-
TBX15	6913	T-box 15	transcription, DNA-templated	Biological process	-
HTR2B	3357	5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled	positive regulation of endothelial cell proliferation	Biological process	19308295
HPS4	89781	Hermansky-Pudlak syndrome 4	protein stabilization	Biological process	12663659
TTC26	79989	tetratricopeptide repeat domain 26	smoothened signaling pathway	Biological process	-
RASGRP1	10125	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	regulation of phosphatidylinositol 3-kinase signaling	Biological process	-
ATP2A2	488	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	calcium ion transport from cytosol to endoplasmic reticulum	Biological process	16402920
ZNF485	220992	zinc finger protein 485	DNA binding	Molecular function	-
DYX1C1	161582	dyslexia susceptibility 1 candidate 1	estrogen receptor binding	Molecular function	19423554
STAG1	10274	stromal antigen 1	cellular protein metabolic process	Biological process	-
IRS1	3667	insulin receptor substrate 1	lipid catabolic process	Biological process	-
HBZ	3050	hemoglobin, zeta	protein binding	Molecular function	11159543
CNTROB	116840	centrobin, centrosomal BRCA2 interacting protein	centriole	Cellular component	16275750
ERCC4	2072	excision repair cross-complementation group 4	DNA repair	Biological process	-
EDAR	10913	ectodysplasin A receptor	protein binding	Molecular function	11039935
SYK	6850	spleen tyrosine kinase	extrinsic component of cytoplasmic side of plasma membrane	Cellular component	-
HSP90AA1	3320	heat shock protein 90kDa alpha (cytosolic), class A member 1	extracellular exosome	Cellular component	11487543
BICD1	636	bicaudal D homolog 1 (Drosophila)	positive regulation of receptor-mediated endocytosis	Biological process	20164183
PHB2	11331	prohibitin 2	sister chromatid cohesion	Biological process	23548868
RPL39	6170	ribosomal protein L39	cytosol	Cellular component	-
RAB26	25837	RAB26, member RAS oncogene family	intrinsic component of plasma membrane	Cellular component	-
ZNF613	79898	zinc finger protein 613	regulation of transcription, DNA-templated	Biological process	-
ARFGAP1	55738	ADP-ribosylation factor GTPase activating protein 1	protein transport	Biological process	-
AGT	183	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	cellular sodium ion homeostasis	Biological process	-
NDFIP1	80762	Nedd4 family interacting protein 1	positive regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	12761501
PRKCE	5581	protein kinase C, epsilon	response to morphine	Biological process	-
SYPL1	6856	synaptophysin-like 1	extracellular exosome	Cellular component	19056867
SOX9	6662	SRY (sex determining region Y)-box 9	protein complex assembly	Biological process	20530484
CTSH	1512	cathepsin H	acrosomal vesicle	Cellular component	-
PLEKHF1	79156	pleckstrin homology domain containing, family F (with FYVE domain) member 1	vesicle organization	Biological process	22115783
PLCB4	5332	phospholipase C, beta 4	phospholipase C activity	Molecular function	8530101
RPL13	6137	ribosomal protein L13	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Biological process	-
ATP10D	57205	ATPase, class V, type 10D	endoplasmic reticulum membrane	Cellular component	-
SHH	6469	sonic hedgehog	osteoblast development	Biological process	-
LCMT2	9836	leucine carboxyl methyltransferase 2	protein binding	Molecular function	12853982
NR1H2	7376	nuclear receptor subfamily 1, group H, member 2	transcription initiation from RNA polymerase II promoter	Biological process	-
GATA3	2625	GATA binding protein 3	negative regulation of transcription, DNA-templated	Biological process	19674970
CD38	952	CD38 molecule	response to hypoxia	Biological process	-
ESRP2	80004	epithelial splicing regulatory protein 2	regulation of RNA splicing	Biological process	19285943
OXT	5020	oxytocin/neurophysin I prepropeptide	secretory granule	Cellular component	-
CHI3L1	1116	chitinase 3-like 1 (cartilage glycoprotein-39)	lung development	Biological process	18403759
FST	10468	follistatin	hair follicle morphogenesis	Biological process	-
PAQR8	85315	progestin and adipoQ receptor family member VIII	multicellular organismal development	Biological process	-
STK10	6793	serine/threonine kinase 10	regulation of apoptotic process	Biological process	-
UNK	85451	unkempt family zinc finger	mRNA CDS binding	Molecular function	25737280
AGBL2	79841	ATP/GTP binding protein-like 2	cytosol	Cellular component	-
ESRRA	2101	estrogen-related receptor alpha	steroid hormone mediated signaling pathway	Biological process	-
FAR2	55711	fatty acyl CoA reductase 2	peroxisomal membrane	Cellular component	-
P4HB	5034	prolyl 4-hydroxylase, beta polypeptide	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	Biological process	7753822
JUN	3725	jun proto-oncogene	RNA polymerase II distal enhancer sequence-specific DNA binding	Molecular function	19861239
SCUBE1	80274	signal peptide, CUB domain, EGF-like 1	endothelial cell differentiation	Biological process	12270931
LRRTM1	347730	leucine rich repeat transmembrane neuronal 1	molecular_function	Molecular function	-
ROR1	4919	receptor tyrosine kinase-like orphan receptor 1	plasma membrane	Cellular component	1334494
MARVELD3	91862	MARVEL domain containing 3	response to osmotic stress	Biological process	24567356
SRSF5	6430	serine/arginine-rich splicing factor 5	mRNA splice site selection	Biological process	7556075
CD276	80381	CD276 molecule	immune response	Biological process	11224528
UNC13B	10497	unc-13 homolog B (C. elegans)	innervation	Biological process	-
HOXD9	3235	homeobox D9	negative regulation of transcription from RNA polymerase II promoter	Biological process	1756725
CNP	1267	2',3'-cyclic nucleotide 3' phosphodiesterase	melanosome	Cellular component	-
PDCD6IP	10015	programmed cell death 6 interacting protein	protein transport	Biological process	-
MYO9B	4650	myosin IXB	actin filament binding	Molecular function	-
RIPK1	8737	receptor (TNFRSF)-interacting serine-threonine kinase 1	toll-like receptor 3 signaling pathway	Biological process	-
ANXA1	301	annexin A1	arachidonic acid secretion	Biological process	-
TICRR	90381	TOPBP1-interacting checkpoint and replication regulator	protein binding	Molecular function	20080954
NDST1	3340	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	embryonic viscerocranium morphogenesis	Biological process	-
NOA1	84273	nitric oxide associated 1	poly(A) RNA binding	Molecular function	22658674
KAT8	84148	K(lysine) acetyltransferase 8	chromatin organization	Biological process	-
KHSRP	8570	KH-type splicing regulatory protein	membrane	Cellular component	19946888
NRP1	8829	neuropilin 1	sympathetic ganglion development	Biological process	-
TERF2	7014	telomeric repeat binding factor 2	protein localization to chromosome, telomeric region	Biological process	17499040
ITGA2B	3674	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	platelet aggregation	Biological process	-
PRAMEF1	65121	PRAME family member 1	negative regulation of cell differentiation	Biological process	-
CHRNA3	1136	cholinergic receptor, nicotinic, alpha 3 (neuronal)	postsynaptic density	Cellular component	-
GATA4	2626	GATA binding protein 4	nucleus	Cellular component	12845333
DRD4	1815	dopamine receptor D4	regulation of neurotransmitter secretion	Biological process	-
SMARCA4	6597	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	regulation of transcription from RNA polymerase II promoter	Biological process	8804307
ZNF358	140467	zinc finger protein 358	stem cell maintenance	Biological process	-
CHRDL1	91851	chordin-like 1	negative regulation of BMP signaling pathway	Biological process	-
GNL1	2794	guanine nucleotide binding protein-like 1	ribosome biogenesis	Biological process	-
BCL2	596	B-cell CLL/lymphoma 2	negative regulation of autophagy	Biological process	18309324
MRPL3	11222	mitochondrial ribosomal protein L3	translation	Biological process	2891103
MGST1	4257	microsomal glutathione S-transferase 1	xenobiotic metabolic process	Biological process	-
VPS37B	79720	vacuolar protein sorting 37 homolog B (S. cerevisiae)	endosomal transport	Biological process	-
SMURF2	64750	SMAD specific E3 ubiquitin protein ligase 2	nucleus	Cellular component	11163210
FOSL1	8061	FOS-like antigen 1	response to hydrogen peroxide	Biological process	-
CDH13	1012	cadherin 13	adiponectin binding	Molecular function	-
AQP7P3	441432	aquaporin 7 pseudogene 3	extracellular exosome	Cellular component	23376485
ACTR3	10096	ARP3 actin-related protein 3 homolog (yeast)	ATP binding	Molecular function	-
DYNC1I1	1780	dynein, cytoplasmic 1, intermediate chain 1	protein binding	Molecular function	14985359
TAF1	6872	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Biological process	15053879
PAFAH1B1	5048	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	actin cytoskeleton organization	Biological process	10729324
TRPM5	29850	transient receptor potential cation channel, subfamily M, member 5	plasma membrane	Cellular component	-
GSTO1	9446	glutathione S-transferase omega 1	glutathione dehydrogenase (ascorbate) activity	Molecular function	11511179
SYCP2	10388	synaptonemal complex protein 2	protein heterodimerization activity	Molecular function	-
NPY5R	4889	neuropeptide Y receptor Y5	neuron projection	Cellular component	-
KDM2B	84678	lysine (K)-specific demethylase 2B	rRNA binding	Molecular function	-
CHPF2	54480	chondroitin polymerizing factor 2	carbohydrate metabolic process	Biological process	-
RAB40AL	282808	RAB40A, member RAS oncogene family-like	regulation of exocytosis	Biological process	-
S100A9	6280	S100 calcium binding protein A9	inflammatory response	Biological process	3313057
ATG4A	115201	autophagy related 4A, cysteine peptidase	nucleophagy	Biological process	-
SDC2	6383	syndecan 2	glycosaminoglycan biosynthetic process	Biological process	-
SNRPA	6626	small nuclear ribonucleoprotein polypeptide A	RNA splicing	Biological process	-
OTP	23440	orthopedia homeobox	forebrain neuron differentiation	Biological process	-
DUSP21	63904	dual specificity phosphatase 21	protein binding	Molecular function	25416956
ZHX1	11244	zinc fingers and homeoboxes 1	transcription, DNA-templated	Biological process	-
NEU2	4759	sialidase 2 (cytosolic sialidase)	protein binding	Molecular function	25416956
SLC20A1	6574	solute carrier family 20 (phosphate transporter), member 1	transport	Biological process	8041748
ALDOC	230	aldolase C, fructose-bisphosphate	protein binding	Molecular function	11399750
HAUS8	93323	HAUS augmin-like complex, subunit 8	spindle pole	Cellular component	-
DGCR8	54487	DGCR8 microprocessor complex subunit	heme binding	Molecular function	24449907
MRPS11	64963	mitochondrial ribosomal protein S11	structural constituent of ribosome	Molecular function	-
SPTB	6710	spectrin, beta, erythrocytic	spectrin	Cellular component	-
HIST1H3J	8356	histone cluster 1, H3j	blood coagulation	Biological process	-
MAP3K12	7786	mitogen-activated protein kinase kinase kinase 12	activation of mitophagy in response to mitochondrial depolarization	Biological process	22020285
AP2A1	160	adaptor-related protein complex 2, alpha 1 subunit	protein binding	Molecular function	19116314
AOC2	314	amine oxidase, copper containing 2 (retina-specific)	phenethylamine:oxygen oxidoreductase (deaminating) activity	Molecular function	-
APLN	8862	apelin	positive regulation of cell proliferation	Biological process	-
CD247	919	CD247 molecule	regulation of defense response to virus by virus	Biological process	-
CIAPIN1	57019	cytokine induced apoptosis inhibitor 1	hemopoiesis	Biological process	-
CXCL10	3627	chemokine (C-X-C motif) ligand 10	muscle organ development	Biological process	8798675
CLPX	10845	caseinolytic mitochondrial matrix peptidase chaperone subunit	proteolysis involved in cellular protein catabolic process	Biological process	16115876
RXRG	6258	retinoid X receptor, gamma	skeletal muscle tissue development	Biological process	-
SLC39A5	283375	solute carrier family 39 (zinc transporter), member 5	zinc II ion transport	Biological process	-
VSX2	338917	visual system homeobox 2	transcription, DNA-templated	Biological process	-
PROX1	5629	prospero homeobox 1	positive regulation of endothelial cell proliferation	Biological process	19210544
CEACAM16	388551	carcinoembryonic antigen-related cell adhesion molecule 16	stereocilium bundle tip	Cellular component	-
PARK7	11315	parkinson protein 7	regulation of androgen receptor signaling pathway	Biological process	11477070
SOD1	6647	superoxide dismutase 1, soluble	auditory receptor cell stereocilium organization	Biological process	-
PYCARD	29108	PYD and CARD domain containing	cysteine-type endopeptidase activator activity involved in apoptotic process	Molecular function	12019269
CAMKK2	10645	calcium/calmodulin-dependent protein kinase kinase 2, beta	nucleus	Cellular component	-
DPPA4	55211	developmental pluripotency associated 4	lung-associated mesenchyme development	Biological process	-
KANK1	23189	KN motif and ankyrin repeat domains 1	beta-catenin binding	Molecular function	16968744
SUV39H2	79723	suppressor of variegation 3-9 homolog 2 (Drosophila)	nuclear heterochromatin	Cellular component	-
GMFB	2764	glia maturation factor, beta	nervous system development	Biological process	1712830
RILPL1	353116	Rab interacting lysosomal protein-like 1	plasma membrane	Cellular component	-
ZNF585A	199704	zinc finger protein 585A	regulation of transcription, DNA-templated	Biological process	-
ATP9A	10079	ATPase, class II, type 9A	early endosome membrane	Cellular component	-
MYO10	4651	myosin X	metabolic process	Biological process	-
RAD52	5893	RAD52 homolog (S. cerevisiae)	regulation of nucleotide-excision repair	Biological process	19506022
SPTBN4	57731	spectrin, beta, non-erythrocytic 4	phospholipid binding	Molecular function	-
AQP1	358	aquaporin 1 (Colton blood group)	wound healing	Biological process	-
PRKD1	5587	protein kinase D1	positive regulation of transcription from RNA polymerase II promoter	Biological process	18059339
JPH3	57338	junctophilin 3	locomotion	Biological process	-
CENPH	64946	centromere protein H	mitotic cell cycle	Biological process	-
TEC	7006	tec protein tyrosine kinase	B cell receptor signaling pathway	Biological process	10518561
CENPF	1063	centromere protein F, 350/400kDa	cytoplasm	Cellular component	12974617
DES	1674	desmin	cytosol	Cellular component	-
GFI1B	8328	growth factor independent 1B transcription repressor	transcription from RNA polymerase II promoter	Biological process	9566867
SEMA6D	80031	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	integral component of membrane	Cellular component	-
ZEB1	6935	zinc finger E-box binding homeobox 1	cartilage development	Biological process	-
NELFA	7469	negative elongation factor complex member A	transcription from RNA polymerase II promoter	Biological process	-
ASCL1	429	achaete-scute family bHLH transcription factor 1	ventral spinal cord interneuron fate commitment	Biological process	-
MTMR2	8898	myotubularin related protein 2	negative regulation of receptor internalization	Biological process	-
RGS20	8601	regulator of G-protein signaling 20	nucleus	Cellular component	-
NR4A3	8013	nuclear receptor subfamily 4, group A, member 3	transcription factor complex	Cellular component	-
ATP6AP1	537	ATPase, H+ transporting, lysosomal accessory protein 1	establishment of organelle localization	Biological process	-
SQSTM1	8878	sequestosome 1	positive regulation of apoptotic process	Biological process	-
GPRC5C	55890	G protein-coupled receptor, class C, group 5, member C	G-protein coupled receptor activity	Molecular function	-
GSTO2	119391	glutathione S-transferase omega 2	cellular response to arsenic-containing substance	Biological process	15970797
NACC2	138151	NACC family member 2, BEN and BTB (POZ) domain containing	histone deacetylase binding	Molecular function	22926524
GAS2L1	10634	growth arrest-specific 2 like 1	negative regulation of erythrocyte differentiation	Biological process	19375645
MT1G	4495	metallothionein 1G	monocyte differentiation	Biological process	8119276
YBX3	8531	Y box binding protein 3	in utero embryonic development	Biological process	-
Sep-12	124404	septin 12	cleavage furrow	Cellular component	-
NBR1	4077	neighbor of BRCA1 gene 1	regulation of bone mineralization	Biological process	-
OR4C15	81309	olfactory receptor, family 4, subfamily C, member 15	plasma membrane	Cellular component	-
KIAA1033	23325	KIAA1033	endosome organization	Biological process	23676666
CCT8L2	150160	chaperonin containing TCP1, subunit 8 (theta)-like 2	potassium ion transmembrane transport	Biological process	10585773
ASH1L	55870	ash1 (absent, small, or homeotic)-like (Drosophila)	bicellular tight junction	Cellular component	-
ZNF423	23090	zinc finger protein 423	negative regulation of transcription, DNA-templated	Biological process	10660046
SLC6A20	54716	solute carrier family 6 (proline IMINO transporter), member 20	plasma membrane	Cellular component	-
PHB	5245	prohibitin	negative regulation of androgen receptor signaling pathway	Biological process	18487222
MIB1	57534	mindbomb E3 ubiquitin protein ligase 1	heart looping	Biological process	-
AGT	183	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	positive regulation of vasodilation	Biological process	-
NUP85	79902	nucleoporin 85kDa	nuclear membrane	Cellular component	-
CLU	1191	clusterin	microglial cell activation	Biological process	15857407
RORA	6095	RAR-related orphan receptor A	triglyceride homeostasis	Biological process	11053433
ETV5	2119	ets variant 5	nucleus	Cellular component	19443906
UHRF1BP1	54887	UHRF1 binding protein 1	identical protein binding	Molecular function	15361834
YWHAZ	7534	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta	response to drug	Biological process	-
FTH1	2495	ferritin, heavy polypeptide 1	transmembrane transport	Biological process	-
SOX9	6662	SRY (sex determining region Y)-box 9	positive regulation of protein phosphorylation	Biological process	-
TXNL1	9352	thioredoxin-like 1	protein folding	Biological process	-
ZSCAN16	80345	zinc finger and SCAN domain containing 16	regulation of transcription, DNA-templated	Biological process	-
GUCY1A3	2982	guanylate cyclase 1, soluble, alpha 3	guanylate cyclase activity	Molecular function	-
RHOA	387	ras homolog family member A	ephrin receptor signaling pathway	Biological process	-
POLD1	5424	polymerase (DNA directed), delta 1, catalytic subunit	DNA-dependent DNA replication	Biological process	-
FOXF1	2294	forkhead box F1	lung development	Biological process	19500772
ADORA1	134	adenosine A1 receptor	negative regulation of mucus secretion	Biological process	-
DMP1	1758	dentin matrix acidic phosphoprotein 1	nucleus	Cellular component	-
KISS1R	84634	KISS1 receptor	neuropeptide receptor activity	Molecular function	11387329
CFD	1675	complement factor D (adipsin)	extracellular region	Cellular component	-
LRMP	4033	lymphoid-restricted membrane protein	chromosome	Cellular component	-
SEC24A	10802	SEC24 family member A	molecular_function	Molecular function	-
DDR1	780	discoidin domain receptor tyrosine kinase 1	protein binding	Molecular function	16337946
DAGLB	221955	diacylglycerol lipase, beta	metal ion binding	Molecular function	-
HCFC1	3054	host cell factor C1	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
GCGR	2642	glucagon receptor	guanyl-nucleotide exchange factor activity	Molecular function	-
ABCC8	6833	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	ATP binding	Molecular function	-
EXO1	9156	exonuclease 1	exonuclease activity	Molecular function	9788596
GINS4	84296	GINS complex subunit 4 (Sld5 homolog)	protein binding	Molecular function	16189514
SOS1	6654	son of sevenless homolog 1 (Drosophila)	GTPase activator activity	Molecular function	9790532
LIN28A	79727	lin-28 homolog A (C. elegans)	cytosol	Cellular component	-
PDZD2	23037	PDZ domain containing 2	endoplasmic reticulum	Cellular component	12671685
TF	7018	transferrin	endosome membrane	Cellular component	-
MYO18A	399687	myosin XVIIIA	Golgi ribbon formation	Biological process	19837035
TACC2	10579	transforming, acidic coiled-coil containing protein 2	regulation of microtubule-based process	Biological process	-
PRKAR1B	5575	protein kinase, cAMP-dependent, regulatory, type I, beta	renal water homeostasis	Biological process	-
TPK1	27010	thiamin pyrophosphokinase 1	small molecule metabolic process	Biological process	-
ITSN1	6453	intersectin 1 (SH3 domain protein)	positive regulation of protein kinase B signaling	Biological process	-
NOTCH1	4851	notch 1	coronary artery morphogenesis	Biological process	-
F2	2147	coagulation factor II (thrombin)	regulation of blood coagulation	Biological process	12855810
RHAG	6005	Rh-associated glycoprotein	transmembrane transport	Biological process	-
WFDC1	58189	WAP four-disulfide core domain 1	molecular_function	Molecular function	-
POLR3E	55718	polymerase (RNA) III (DNA directed) polypeptide E (80kD)	centrosome	Cellular component	-
DAW1	164781	dynein assembly factor with WDR repeat domains 1	cilium	Cellular component	-
NEUROD1	4760	neuronal differentiation 1	transcription factor binding	Molecular function	10545951
ADD1	118	adducin 1 (alpha)	poly(A) RNA binding	Molecular function	22658674
ADCY7	113	adenylate cyclase 7	small molecule metabolic process	Biological process	-
ADAMTS12	81792	ADAM metallopeptidase with thrombospondin type 1 motif, 12	zinc ion binding	Molecular function	-
TFDP1	7027	transcription factor Dp-1	negative regulation of fat cell proliferation	Biological process	-
PITX2	5308	paired-like homeodomain 2	deltoid tuberosity development	Biological process	18312615
XRCC6	2547	X-ray repair complementing defective repair in Chinese hamster cells 6	positive regulation of type I interferon production	Biological process	-
CAV1	857	caveolin 1, caveolae protein, 22kDa	membrane depolarization	Biological process	-
USP45	85015	ubiquitin specific peptidase 45	ubiquitin-specific protease activity	Molecular function	14715245
LYVE1	10894	lymphatic vessel endothelial hyaluronan receptor 1	transmembrane signaling receptor activity	Molecular function	-
ABCG5	64240	ATP-binding cassette, sub-family G (WHITE), member 5	response to drug	Biological process	-
CPSF7	79869	cleavage and polyadenylation specific factor 7, 59kDa	membrane	Cellular component	19946888
PRKAG2	51422	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	regulation of fatty acid biosynthetic process	Biological process	-
UBC	7316	ubiquitin C	ubiquitin homeostasis	Biological process	-
UQCRC2	7385	ubiquinol-cytochrome c reductase core protein II	metalloendopeptidase activity	Molecular function	-
KLKB1	3818	kallikrein B, plasma (Fletcher factor) 1	blood coagulation	Biological process	-
TRIM27	5987	tripartite motif containing 27	integral component of plasma membrane	Cellular component	3078962
COL5A1	1289	collagen, type V, alpha 1	cell adhesion	Biological process	18305566
LIN7C	55327	lin-7 homolog C (C. elegans)	cytoplasm	Cellular component	23201090
MACC1	346389	metastasis associated in colon cancer 1	nucleus	Cellular component	-
HLA-G	3135	major histocompatibility complex, class I, G	membrane	Cellular component	19946888
PRPS1	5631	phosphoribosyl pyrophosphate synthetase 1	ATP binding	Molecular function	16939420
PKM	5315	pyruvate kinase, muscle	potassium ion binding	Molecular function	-
CD38	952	CD38 molecule	transferase activity	Molecular function	-
PTK7	5754	protein tyrosine kinase 7 (inactive)	establishment of epithelial cell apical/basal polarity	Biological process	-
CAD	790	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	neuronal cell body	Cellular component	-
NFKB1	4790	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	negative regulation of interleukin-12 biosynthetic process	Biological process	-
NUP214	8021	nucleoporin 214kDa	regulation of cell cycle	Biological process	-
SSTR1	6751	somatostatin receptor 1	spermatogenesis	Biological process	-
THY1	7070	Thy-1 cell surface antigen	integral component of plasma membrane	Cellular component	2864289
ARF4	378	ADP-ribosylation factor 4	GTPase activity	Molecular function	-
ATP4A	495	ATPase, H+/K+ exchanging, alpha polypeptide	magnesium ion binding	Molecular function	-
GRIK3	2899	glutamate receptor, ionotropic, kainate 3	ionotropic glutamate receptor signaling pathway	Biological process	-
ING2	3622	inhibitor of growth family, member 2	regulation of cellular senescence	Biological process	21124965
POU2F1	5451	POU class 2 homeobox 1	nucleus	Cellular component	11891224
ADAMTS20	80070	ADAM metallopeptidase with thrombospondin type 1 motif, 20	proteolysis	Biological process	-
TCF15	6939	transcription factor 15 (basic helix-loop-helix)	mesenchymal to epithelial transition	Biological process	-
CASP14	23581	caspase 14, apoptosis-related cysteine peptidase	cornification	Biological process	18309324
UHRF1	29128	ubiquitin-like with PHD and ring finger domains 1	heterochromatin	Cellular component	17967883
LOR	4014	loricrin	protein binding	Molecular function	7592852
TTF2	8458	transcription termination factor, RNA polymerase II	protein binding	Molecular function	17577209
PIK3R1	5295	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	positive regulation of glucose import	Biological process	8052599
PTGFR	5737	prostaglandin F receptor (FP)	cellular response to prostaglandin D stimulus	Biological process	18508192
TFAM	7019	transcription factor A, mitochondrial	cytosol	Cellular component	-
LINC01588	283551	long intergenic non-protein coding RNA 1588	protein binding	Molecular function	25416956
RAB32	10981	RAB32, member RAS oncogene family	protein binding	Molecular function	21808068
ABCC3	8714	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	ATPase activity, coupled to transmembrane movement of substances	Molecular function	-
SNRNP200	23020	small nuclear ribonucleoprotein 200kDa (U5)	membrane	Cellular component	16210410
CHRNB2	1141	cholinergic receptor, nicotinic, beta 2 (neuronal)	central nervous system projection neuron axonogenesis	Biological process	-
DDB2	1643	damage-specific DNA binding protein 2, 48kDa	histone H2A monoubiquitination	Biological process	22334663
GCFC2	6936	GC-rich sequence DNA-binding factor 2	spliceosomal complex assembly	Biological process	24304693
TP53BP2	7159	tumor protein p53 binding protein 2	cell cycle	Biological process	-
CHST6	4166	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6	sulfur compound metabolic process	Biological process	11352640
MYH9	4627	myosin, heavy chain 9, non-muscle	in utero embryonic development	Biological process	-
CLEC5A	23601	C-type lectin domain family 5, member A	carbohydrate binding	Molecular function	-
TXNRD2	10587	thioredoxin reductase 2	cell redox homeostasis	Biological process	-
EEF1E1	9521	eukaryotic translation elongation factor 1 epsilon 1	positive regulation of apoptotic process	Biological process	-
CIB1	10519	calcium and integrin binding 1 (calmyrin)	neuronal cell body	Cellular component	21215777
P2RX1	5023	purinergic receptor P2X, ligand gated ion channel, 1	platelet activation	Biological process	-
GCHFR	2644	GTP cyclohydrolase I feedback regulator	nuclear membrane	Cellular component	16778797
TP73	7161	tumor protein p73	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	Biological process	18174154
ARC	23237	activity-regulated cytoskeleton-associated protein	endocytosis	Biological process	-
RC3H1	149041	ring finger and CCCH-type domains 1	negative regulation of B cell proliferation	Biological process	-
PIK3C3	5289	phosphatidylinositol 3-kinase, catalytic subunit type 3	cytoplasm	Cellular component	-
CAPN3	825	calpain 3, (p94)	protein complex scaffold	Molecular function	-
CLIC1	1192	chloride intracellular channel 1	cytoplasm	Cellular component	10793131
GPR31	2853	G protein-coupled receptor 31	G-protein coupled receptor activity	Molecular function	-
HSP90AB1	3326	heat shock protein 90kDa alpha (cytosolic), class B member 1	axon guidance	Biological process	-
AMICA1	120425	adhesion molecule, interacts with CXADR antigen 1	cell adhesion molecule binding	Molecular function	12869515
KRTAP10-9	386676	keratin associated protein 10-9	protein binding	Molecular function	25416956
CACNA1H	8912	calcium channel, voltage-dependent, T type, alpha 1H subunit	scaffold protein binding	Molecular function	21084288
ZNF417	147687	zinc finger protein 417	DNA binding	Molecular function	-
VAMP7	6845	vesicle-associated membrane protein 7	late endosome membrane	Cellular component	10459012
CHRD	8646	chordin	mesoderm formation	Biological process	-
FCRLA	84824	Fc receptor-like A	extracellular region	Cellular component	-
USP19	10869	ubiquitin specific peptidase 19	regulation of proteasomal protein catabolic process	Biological process	-
SLC25A38	54977	solute carrier family 25, member 38	transporter activity	Molecular function	-
CENPJ	55835	centromere protein J	centriole replication	Biological process	17681131
CD44	960	CD44 molecule (Indian blood group)	cytoplasm	Cellular component	-
FOXK1	221937	forkhead box K1	cell differentiation	Biological process	-
SUCO	51430	SUN domain containing ossification factor	membrane	Cellular component	-
MTAP	4507	methylthioadenosine phosphorylase	nucleus	Cellular component	-
CYSLTR1	10800	cysteinyl leukotriene receptor 1	chemotaxis	Biological process	-
BPTF	2186	bromodomain PHD finger transcription factor	nucleoplasm	Cellular component	-
SNRNP200	23020	small nuclear ribonucleoprotein 200kDa (U5)	identical protein binding	Molecular function	22365833
PRKACA	5566	protein kinase, cAMP-dependent, catalytic, alpha	cell communication by electrical coupling involved in cardiac conduction	Biological process	23507255
NRDE2	55051	NRDE-2, necessary for RNA interference, domain containing	biological_process	Biological process	-
B3GAT3	26229	beta-1,3-glucuronyltransferase 3	protein binding	Molecular function	24425863
GMPPA	29926	GDP-mannose pyrophosphorylase A	protein N-linked glycosylation via asparagine	Biological process	-
LRRC8E	80131	leucine rich repeat containing 8 family, member E	ion transport	Biological process	-
NLRP10	338322	NLR family, pyrin domain containing 10	positive regulation of interleukin-6 secretion	Biological process	22672233
SFRP2	6423	secreted frizzled-related protein 2	negative regulation of Wnt signaling pathway	Biological process	20208569
KCND1	3750	potassium channel, voltage gated Shal related subfamily D, member 1	dendrite	Cellular component	-
MYOD1	4654	myogenic differentiation 1	regulation of alternative mRNA splicing, via spliceosome	Biological process	-
CLK4	57396	CDC-like kinase 4	regulation of RNA splicing	Biological process	19168442
CDK5	1020	cyclin-dependent kinase 5	positive regulation of protein targeting to membrane	Biological process	-
NOX3	50508	NADPH oxidase 3	otolith development	Biological process	-
PROX1	5629	prospero homeobox 1	protein binding	Molecular function	15205472
CNPY3	10695	canopy FGF signaling regulator 3	receptor binding	Molecular function	-
UQCR11	10975	ubiquinol-cytochrome c reductase, complex III subunit XI	generation of precursor metabolites and energy	Biological process	9161705
CHM	1121	choroideremia (Rab escort protein 1)	response to stimulus	Biological process	-
TMEM231	79583	transmembrane protein 231	smoothened signaling pathway	Biological process	-
SUPT3H	8464	suppressor of Ty 3 homolog (S. cerevisiae)	transcription coactivator activity	Molecular function	11564863
TRPM6	140803	transient receptor potential cation channel, subfamily M, member 6	brush border membrane	Cellular component	-
TLR4	7099	toll-like receptor 4	integral component of plasma membrane	Cellular component	15027902
KDM4C	23081	lysine (K)-specific demethylase 4C	histone demethylase activity	Molecular function	-
HSPA1B	3304	heat shock 70kDa protein 1B	negative regulation of inclusion body assembly	Biological process	15603737
APLP2	334	amyloid beta (A4) precursor-like protein 2	suckling behavior	Biological process	-
KCNJ4	3761	potassium channel, inwardly rectifying subfamily J, member 4	inward rectifier potassium channel activity	Molecular function	-
ZNF879	345462	zinc finger protein 879	nucleus	Cellular component	-
DYRK1A	1859	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	peptidyl-tyrosine phosphorylation	Biological process	-
RAB36	9609	RAB36, member RAS oncogene family	intracellular protein transport	Biological process	-
GLCE	26035	glucuronic acid epimerase	glycosaminoglycan biosynthetic process	Biological process	-
DYRK4	8798	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4	cytoplasm	Cellular component	-
HACE1	57531	HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1	endoplasmic reticulum	Cellular component	-
ITGB1BP1	9270	integrin beta 1 binding protein 1	cellular response to fibroblast growth factor stimulus	Biological process	20616313
SUPT3H	8464	suppressor of Ty 3 homolog (S. cerevisiae)	SAGA complex	Cellular component	-
LPXN	9404	leupaxin	regulation of cell adhesion mediated by integrin	Biological process	-
SAMD4A	23034	sterile alpha motif domain containing 4A	synapse	Cellular component	-
BTG2	7832	BTG family, member 2	transcription, DNA-templated	Biological process	-
FXR2	9513	fragile X mental retardation, autosomal homolog 2	polysome	Cellular component	-
ANXA4	307	annexin A4	negative regulation of NF-kappaB transcription factor activity	Biological process	20237821
SEZ6	124925	seizure related 6 homolog (mouse)	positive regulation of dendrite development	Biological process	-
PKN2	5586	protein kinase N2	transcription, DNA-templated	Biological process	-
KDM4A	9682	lysine (K)-specific demethylase 4A	chromatin organization	Biological process	-
COL1A2	1278	collagen, type I, alpha 2	leukocyte migration	Biological process	-
BHLHE40	8553	basic helix-loop-helix family, member e40	nucleoplasm	Cellular component	-
DRD2	1813	dopamine receptor D2	response to drug	Biological process	-
ZC3H12A	80149	zinc finger CCCH-type containing 12A	negative regulation of nitric oxide biosynthetic process	Biological process	18178554
ATF3	467	activating transcription factor 3	PERK-mediated unfolded protein response	Biological process	-
CBLC	23624	Cbl proto-oncogene C, E3 ubiquitin protein ligase	phosphotyrosine binding	Molecular function	14661060
CALCR	799	calcitonin receptor	cytosol	Cellular component	8078488
PPIA	5478	peptidylprolyl isomerase A (cyclophilin A)	viral release from host cell	Biological process	21711559
ESYT3	83850	extended synaptotagmin-like protein 3	phospholipid binding	Molecular function	-
RPS6KA1	6195	ribosomal protein S6 kinase, 90kDa, polypeptide 1	ATP binding	Molecular function	-
FAM57B	83723	family with sequence similarity 57, member B	Golgi membrane	Cellular component	-
ZFP36L1	677	ZFP36 ring finger protein-like 1	cytosol	Cellular component	-
INHBA	3624	inhibin, beta A	eyelid development in camera-type eye	Biological process	-
RELA	5970	v-rel avian reticuloendotheliosis viral oncogene homolog A	positive regulation of cell proliferation	Biological process	23091055
DCP2	167227	decapping mRNA 2	RISC complex	Cellular component	20616046
NSFL1C	55968	NSFL1 (p97) cofactor (p47)	membrane fusion	Biological process	-
POLG	5428	polymerase (DNA directed), gamma	DNA metabolic process	Biological process	8884268
DMRTC2	63946	DMRT-like family C2	metal ion binding	Molecular function	-
STAR	6770	steroidogenic acute regulatory protein	bile acid biosynthetic process	Biological process	-
FOSB	2354	FBJ murine osteosarcoma viral oncogene homolog B	cellular response to calcium ion	Biological process	-
TBL1X	6907	transducin (beta)-like 1X-linked	sensory perception of sound	Biological process	10330347
PSMC4	5704	proteasome (prosome, macropain) 26S subunit, ATPase, 4	innate immune response	Biological process	-
SERPINB9	5272	serpin peptidase inhibitor, clade B (ovalbumin), member 9	protection from natural killer cell mediated cytotoxicity	Biological process	21795594
STX5	6811	syntaxin 5	SNARE binding	Molecular function	-
DHX34	9704	DEAH (Asp-Glu-Ala-His) box polypeptide 34	membrane	Cellular component	19946888
CAPN9	10753	calpain 9	cytoplasm	Cellular component	-
FEM1B	10116	fem-1 homolog b (C. elegans)	nucleoplasm	Cellular component	-
PRPH2	5961	peripherin 2 (retinal degeneration, slow)	cell adhesion	Biological process	-
GNB1	2782	guanine nucleotide binding protein (G protein), beta polypeptide 1	heterotrimeric G-protein complex	Cellular component	1543505
TMBIM1	64114	transmembrane BAX inhibitor motif containing 1	death receptor binding	Molecular function	21107705
ZNF12	7559	zinc finger protein 12	nucleoplasm	Cellular component	-
PIP5K1B	8395	phosphatidylinositol-4-phosphate 5-kinase, type I, beta	small molecule metabolic process	Biological process	-
CXCL3	2921	chemokine (C-X-C motif) ligand 3	CXCR chemokine receptor binding	Molecular function	-
OR11H12	440153	olfactory receptor, family 11, subfamily H, member 12	G-protein coupled receptor signaling pathway	Biological process	-
NFIA	4774	nuclear factor I/A	positive regulation of transcription from RNA polymerase II promoter	Biological process	17010934
PROX1	5629	prospero homeobox 1	negative regulation of cell proliferation	Biological process	17062673
GNG8	94235	guanine nucleotide binding protein (G protein), gamma 8	signal transducer activity	Molecular function	10819326
TCP10L	140290	t-complex 10-like	identical protein binding	Molecular function	17377852
TRIM13	10206	tripartite motif containing 13	integral component of membrane	Cellular component	-
RPS6	6194	ribosomal protein S6	translational initiation	Biological process	-
SOX8	30812	SRY (sex determining region Y)-box 8	DNA binding	Molecular function	10684944
TUBB4A	10382	tubulin, beta 4A class IVa	mitotic cell cycle	Biological process	-
H1FNT	341567	H1 histone family, member N, testis-specific	sperm chromatin condensation	Biological process	15710904
IZUMO1	284359	izumo sperm-egg fusion 1	single fertilization	Biological process	-
JAK1	3716	Janus kinase 1	response to antibiotic	Biological process	16280321
BAZ1B	9031	bromodomain adjacent to zinc finger domain, 1B	chromatin assembly or disassembly	Biological process	-
RAB8B	51762	RAB8B, member RAS oncogene family	cilium assembly	Biological process	17646400
CCR2	729230	chemokine (C-C motif) receptor 2	CCR2 chemokine receptor binding	Molecular function	15995708
NPM2	10361	nucleophosmin/nucleoplasmin 2	chromatin binding	Molecular function	-
CD74	972	CD74 molecule, major histocompatibility complex, class II invariant chain	MHC class II protein complex	Cellular component	-
INSM1	3642	insulinoma-associated 1	endocrine pancreas development	Biological process	-
RAB44	401258	RAB44, member RAS oncogene family	metabolic process	Biological process	-
BST1	683	bone marrow stromal cell antigen 1	NAD(P)+ nucleosidase activity	Molecular function	-
MT1HL1	645745	metallothionein 1H-like 1	metal ion binding	Molecular function	-
AVP	551	arginine vasopressin	hyperosmotic salinity response	Biological process	-
DDX5	1655	DEAD (Asp-Glu-Ala-Asp) box helicase 5	ribonucleoprotein complex	Cellular component	18809582
OTUD7B	56957	OTU deubiquitinase 7B	nucleus	Cellular component	11463333
CDHR2	54825	cadherin-related family member 2	cell junction	Cellular component	-
CLEC12A	160364	C-type lectin domain family 12, member A	integral component of membrane	Cellular component	-
VCAN	1462	versican	hyaluronic acid binding	Molecular function	-
NOTCH2	4853	notch 2	multicellular organismal development	Biological process	9244302
HSP90AB4P	664618	heat shock protein 90kDa alpha (cytosolic), class B member 4, pseudogene	ATP binding	Molecular function	-
TNK2	10188	tyrosine kinase, non-receptor, 2	hormone receptor binding	Molecular function	-
ARHGAP40	343578	Rho GTPase activating protein 40	positive regulation of GTPase activity	Biological process	-
STX17	55014	syntaxin 17	SNAP receptor activity	Molecular function	23217709
OR4D11	219986	olfactory receptor, family 4, subfamily D, member 11	integral component of membrane	Cellular component	-
KANSL1	284058	KAT8 regulatory NSL complex subunit 1	histone H4-K5 acetylation	Biological process	20018852
NAA11	84779	N(alpha)-acetyltransferase 11, NatA catalytic subunit	N-terminal protein amino acid acetylation	Biological process	16638120
CDCA8	55143	cell division cycle associated 8	spindle	Cellular component	-
PEX16	9409	peroxisomal biogenesis factor 16	peroxisome organization	Biological process	15813749
SZT2	23334	seizure threshold 2 homolog (mouse)	central nervous system development	Biological process	-
PKMYT1	9088	protein kinase, membrane associated tyrosine/threonine 1	membrane	Cellular component	19946888
CAND1	55832	cullin-associated and neddylation-dissociated 1	cytoplasm	Cellular component	21249194
PLCG1	5335	phospholipase C, gamma 1	vascular endothelial growth factor receptor signaling pathway	Biological process	-
ACVRL1	94	activin A receptor type II-like 1	lymphangiogenesis	Biological process	-
ZBTB32	27033	zinc finger and BTB domain containing 32	DNA damage response, detection of DNA damage	Biological process	-
NUSAP1	51203	nucleolar and spindle associated protein 1	protein binding	Molecular function	25416956
CASK	8573	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	presynaptic membrane	Cellular component	-
NDFIP2	54602	Nedd4 family interacting protein 2	negative regulation of protein transport	Biological process	18776082
ACSL1	2180	acyl-CoA synthetase long-chain family member 1	triglyceride biosynthetic process	Biological process	-
TP53	7157	tumor protein p53	nuclear body	Cellular component	10360174
LPCAT3	10162	lysophosphatidylcholine acyltransferase 3	phosphatidylserine acyl-chain remodeling	Biological process	-
HLA-A	3105	major histocompatibility complex, class I, A	integral component of lumenal side of endoplasmic reticulum membrane	Cellular component	-
PTGR1	22949	prostaglandin reductase 1	15-oxoprostaglandin 13-oxidase activity	Molecular function	-
EIF4A3	9775	eukaryotic translation initiation factor 4A3	protein binding	Molecular function	10523622
ZNF76	7629	zinc finger protein 76	metal ion binding	Molecular function	-
ARRB2	409	arrestin, beta 2	protein domain specific binding	Molecular function	-
ANK1	286	ankyrin 1, erythrocytic	cytoskeleton organization	Biological process	9430667
PHF2	5253	PHD finger protein 2	methylated histone binding	Molecular function	20129925
LRRK2	120892	leucine-rich repeat kinase 2	peptidyl-serine phosphorylation	Biological process	19576176
ADORA1	134	adenosine A1 receptor	regulation of glomerular filtration	Biological process	-
IFI30	10437	interferon, gamma-inducible protein 30	lysosomal lumen	Cellular component	-
HEY2	23493	hes-related family bHLH transcription factor with YRPW motif 2	cardiac vascular smooth muscle cell development	Biological process	-
DYNC1LI1	51143	dynein, cytoplasmic 1, light intermediate chain 1	condensed chromosome kinetochore	Cellular component	-
RBM22	55696	RNA binding motif protein 22	nucleocytoplasmic transporter activity	Molecular function	21122810
G3BP1	10146	GTPase activating protein (SH3 domain) binding protein 1	protein binding	Molecular function	19615732
FLI1	2313	Fli-1 proto-oncogene, ETS transcription factor	cell differentiation	Biological process	-
PRR7	80758	proline rich 7 (synaptic)	cell junction	Cellular component	-
APOA5	116519	apolipoprotein A-V	tissue regeneration	Biological process	11577099
BRD4	23476	bromodomain containing 4	transcription, DNA-templated	Biological process	-
CFB	629	complement factor B	extracellular space	Cellular component	16502470
DBNL	28988	drebrin-like	Golgi membrane	Cellular component	-
SOX17	64321	SRY (sex determining region Y)-box 17	beta-catenin binding	Molecular function	17875931
CRAT	1384	carnitine O-acetyltransferase	small molecule metabolic process	Biological process	-
CD83	9308	CD83 molecule	external side of plasma membrane	Cellular component	-
HSD17B12	51144	hydroxysteroid (17-beta) dehydrogenase 12	oxidation-reduction process	Biological process	-
CST9	128822	cystatin 9 (testatin)	cysteine-type endopeptidase inhibitor activity	Molecular function	-
SOX9	6662	SRY (sex determining region Y)-box 9	negative regulation of epithelial cell proliferation	Biological process	-
C16orf46	123775	chromosome 16 open reading frame 46	nucleoplasm	Cellular component	-
KDELR2	11014	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2	extracellular exosome	Cellular component	23376485
GOLGA3	2802	golgin A3	nucleolus	Cellular component	-
RINT1	60561	RAD50 interactor 1	endoplasmic reticulum membrane	Cellular component	-
NOVA1	4857	neuro-oncological ventral antigen 1	locomotory behavior	Biological process	8558240
AGTR1	185	angiotensin II receptor, type 1	protein binding	Molecular function	1378723
NKX2-5	1482	NK2 homeobox 5	chromatin binding	Molecular function	16678093
DACT2	168002	dishevelled-binding antagonist of beta-catenin 2	beta-catenin binding	Molecular function	-
GNPTAB	79158	N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits	protein binding	Molecular function	25416956
CCR3	1232	chemokine (C-C motif) receptor 3	cell adhesion	Biological process	10201960
SLC6A6	6533	solute carrier family 6 (neurotransmitter transporter), member 6	organic acid transmembrane transport	Biological process	8010975
FOXO3	2309	forkhead box O3	regulation of transcription from RNA polymerase II promoter	Biological process	-
AASDHPPT	60496	aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase	extracellular exosome	Cellular component	19056867
AZIN1	51582	antizyme inhibitor 1	regulation of cellular amino acid metabolic process	Biological process	-
CXCL10	3627	chemokine (C-X-C motif) ligand 10	defense response to virus	Biological process	-
SCRG1	11341	stimulator of chondrogenesis 1	protein binding	Molecular function	25416956
RPS15A	6210	ribosomal protein S15a	positive regulation of cell cycle	Biological process	15108328
RSPRY1	89970	ring finger and SPRY domain containing 1	zinc ion binding	Molecular function	-
TSPAN12	23554	tetraspanin 12	integral component of membrane	Cellular component	10719184
PRKD2	25865	protein kinase D2	positive regulation of endothelial cell chemotaxis	Biological process	18440775
NFS1	9054	NFS1 cysteine desulfurase	nucleoplasm	Cellular component	-
DEFB121	245934	defensin, beta 121	innate immune response	Biological process	-
EIF3CL	728689	eukaryotic translation initiation factor 3, subunit C-like	regulation of translational initiation	Biological process	-
EFNA4	1945	ephrin-A4	extracellular region	Cellular component	-
B4GALNT2	124872	beta-1,4-N-acetyl-galactosaminyl transferase 2	integral component of membrane	Cellular component	12678917
RRAS2	22800	related RAS viral (r-ras) oncogene homolog 2	GTP binding	Molecular function	-
BNC1	646	basonuclin 1	transcription, DNA-templated	Biological process	-
ERGIC3	51614	ERGIC and golgi 3	endoplasmic reticulum membrane	Cellular component	-
PINK1	65018	PTEN induced putative kinase 1	negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway	Biological process	23261939
ZNF821	55565	zinc finger protein 821	regulation of transcription, DNA-templated	Biological process	-
CCHCR1	54535	coiled-coil alpha-helical rod protein 1	centriole	Cellular component	23644468
PANK1	53354	pantothenate kinase 1	nucleus	Cellular component	-
KDM1A	23028	lysine (K)-specific demethylase 1A	oxidation-reduction process	Biological process	-
ACOT4	122970	acyl-CoA thioesterase 4	unsaturated monocarboxylic acid metabolic process	Biological process	16940157
ARCN1	372	archain 1	membrane	Cellular component	19946888
KITLG	4254	KIT ligand	positive regulation of myeloid leukocyte differentiation	Biological process	-
RTN4R	65078	reticulon 4 receptor	regulation of axonogenesis	Biological process	-
ATP5H	10476	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d	respiratory electron transport chain	Biological process	-
P2RY1	5028	purinergic receptor P2Y, G-protein coupled, 1	relaxation of muscle	Biological process	-
DUSP10	11221	dual specificity phosphatase 10	protein tyrosine phosphatase activity	Molecular function	-
CDK5R1	8851	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	calcium ion binding	Molecular function	-
ERCC6	2074	excision repair cross-complementation group 6	response to oxidative stress	Biological process	17626041
NCKAP1L	3071	NCK-associated protein 1-like	positive regulation of GTPase activity	Biological process	16417406
CREB3L4	148327	cAMP responsive element binding protein 3-like 4	Golgi apparatus	Cellular component	16236796
PSMC5	5705	proteasome (prosome, macropain) 26S subunit, ATPase, 5	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	Biological process	-
VAMP5	10791	vesicle-associated membrane protein 5	SNARE complex	Cellular component	-
AGAP3	116988	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3	GTP binding	Molecular function	-
PKIA	5569	protein kinase (cAMP-dependent, catalytic) inhibitor alpha	cAMP-dependent protein kinase inhibitor activity	Molecular function	1710219
PDLIM7	9260	PDZ and LIM domain 7 (enigma)	multicellular organismal development	Biological process	-
MRPL39	54148	mitochondrial ribosomal protein L39	nucleotide binding	Molecular function	-
ZNF493	284443	zinc finger protein 493	sequence-specific DNA binding transcription factor activity	Molecular function	-
ZNF197	10168	zinc finger protein 197	nucleus	Cellular component	-
ZNF594	84622	zinc finger protein 594	regulation of transcription, DNA-templated	Biological process	-
DNMT3L	29947	DNA (cytosine-5-)-methyltransferase 3-like	regulation of gene expression, epigenetic	Biological process	-
PSME1	5720	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)	G1/S transition of mitotic cell cycle	Biological process	-
HOXA6	3203	homeobox A6	nucleus	Cellular component	-
GDI1	2664	GDP dissociation inhibitor 1	Rab GTPase binding	Molecular function	-
FKBP1B	2281	FK506 binding protein 1B, 12.6 kDa	membrane	Cellular component	12443530
CALM3	808	calmodulin 3 (phosphorylase kinase, delta)	vascular endothelial growth factor receptor signaling pathway	Biological process	-
CYP26C1	340665	cytochrome P450, family 26, subfamily C, polypeptide 1	retinoic acid 4-hydroxylase activity	Molecular function	14532297
MBD1	4152	methyl-CpG binding domain protein 1	nuclear matrix	Cellular component	-
NECAP1	25977	NECAP endocytosis associated 1	protein transport	Biological process	-
STRADB	55437	STE20-related kinase adaptor beta	protein export from nucleus	Biological process	14517248
FARSA	2193	phenylalanyl-tRNA synthetase, alpha subunit	phenylalanyl-tRNA aminoacylation	Biological process	-
CDH23	64072	cadherin-related 23	membrane	Cellular component	11138009
FASN	2194	fatty acid synthase	extracellular exosome	Cellular component	19056867
CDK5R1	8851	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	serine phosphorylation of STAT3 protein	Biological process	-
ITGAM	3684	integrin, alpha M (complement component 3 receptor 3 subunit)	plasma membrane	Cellular component	-
CHIA	27159	chitinase, acidic	positive regulation of chemokine secretion	Biological process	18824549
HS6ST1	9394	heparan sulfate 6-O-sulfotransferase 1	glycosaminoglycan biosynthetic process	Biological process	-
C2CD5	9847	C2 calcium-dependent domain containing 5	positive regulation of vesicle fusion	Biological process	21907143
CALM3	808	calmodulin 3 (phosphorylase kinase, delta)	vesicle	Cellular component	19190083
PRDX3	10935	peroxiredoxin 3	response to oxidative stress	Biological process	18195003
ZSCAN9	7746	zinc finger and SCAN domain containing 9	protein binding	Molecular function	16189514
IRS2	8660	insulin receptor substrate 2	protein binding	Molecular function	17901049
SRP68	6730	signal recognition particle 68kDa	protein targeting to ER	Biological process	-
ZXDA	7789	zinc finger, X-linked, duplicated A	transcription, DNA-templated	Biological process	-
PTPRR	5801	protein tyrosine phosphatase, receptor type, R	negative regulation of ERK1 and ERK2 cascade	Biological process	21724833
HIST1H4E	8367	histone cluster 1, H4e	protein heterotetramerization	Biological process	20498094
VPRBP	9730	Vpr (HIV-1) binding protein	B cell differentiation	Biological process	-
CDK2	1017	cyclin-dependent kinase 2	centrosome duplication	Biological process	19238148
PLSCR1	5359	phospholipid scramblase 1	extracellular matrix	Cellular component	20870722
EMILIN1	11117	elastin microfibril interfacer 1	collagen trimer	Cellular component	-
GJA1	2697	gap junction protein, alpha 1, 43kDa	embryonic digit morphogenesis	Biological process	-
GALR2	8811	galanin receptor 2	learning or memory	Biological process	9480833
SLC35B3	51000	solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3	Golgi membrane	Cellular component	-
SORT1	6272	sortilin 1	plasma membrane to endosome transport	Biological process	11331584
WNT5B	81029	wingless-type MMTV integration site family, member 5B	positive regulation of cell migration	Biological process	19486338
PHEX	5251	phosphate regulating endopeptidase homolog, X-linked	bone mineralization	Biological process	-
WAS	7454	Wiskott-Aldrich syndrome	identical protein binding	Molecular function	10724160
NDUFC2-KCTD14	100532726	NDUFC2-KCTD14 readthrough	integral component of membrane	Cellular component	-
CCT7	10574	chaperonin containing TCP1, subunit 7 (eta)	extracellular exosome	Cellular component	20458337
RPL19	6143	ribosomal protein L19	structural constituent of ribosome	Molecular function	1577483
CTAGE3P	220112	CTAGE family, member 3, pseudogene	cellular_component	Cellular component	-
WIPI1	55062	WD repeat domain, phosphoinositide interacting 1	cytosol	Cellular component	-
MEX3B	84206	mex-3 RNA binding family member B	poly(A) RNA binding	Molecular function	22681889
PDGFC	56034	platelet derived growth factor C	positive regulation of cell division	Biological process	-
IFIT1	3434	interferon-induced protein with tetratricopeptide repeats 1	negative regulation of protein binding	Biological process	19416887
RET	5979	ret proto-oncogene	ureteric bud development	Biological process	-
SFRP1	6422	secreted frizzled-related protein 1	positive regulation of smoothened signaling pathway	Biological process	17035233
CHST2	9435	carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2	integral component of membrane	Cellular component	-
SLCO4A1	28231	solute carrier organic anion transporter family, member 4A1	sodium-independent organic anion transport	Biological process	-
NT5C3B	115024	5'-nucleotidase, cytosolic IIIB	magnesium ion binding	Molecular function	-
TAL1	6886	T-cell acute lymphocytic leukemia 1	positive regulation of cell division	Biological process	20855495
HTR1B	3351	5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	Biological process	1559993
SMN1	6606	survival of motor neuron 1, telomeric	ncRNA metabolic process	Biological process	-
RAB11FIP3	9727	RAB11 family interacting protein 3 (class II)	cytokinesis	Biological process	15601896
PLA2G1B	5319	phospholipase A2, group IB (pancreas)	defense response to Gram-positive bacterium	Biological process	12860195
SIRT4	23409	sirtuin 4	tricarboxylic acid metabolic process	Biological process	-
SHC3	53358	SHC (Src homology 2 domain containing) transforming protein 3	insulin receptor signaling pathway	Biological process	-
TRIM8	81603	tripartite motif containing 8	zinc ion binding	Molecular function	11118312
POMT1	10585	protein-O-mannosyltransferase 1	metal ion binding	Molecular function	-
SLC12A2	6558	solute carrier family 12 (sodium/potassium/chloride transporter), member 2	protein binding	Molecular function	17721439
SLC11A1	6556	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1	wound healing	Biological process	-
RNASEL	6041	ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)	metal ion binding	Molecular function	-
TLX1	3195	T-cell leukemia homeobox 1	protein binding	Molecular function	19559479
RIPK3	11035	receptor-interacting serine-threonine kinase 3	ATP binding	Molecular function	-
PPIE	10450	peptidylprolyl isomerase E (cyclophilin E)	protein binding	Molecular function	11313484
LBH	81606	limb bud and heart development	cytoplasm	Cellular component	-
KCNIP3	30818	Kv channel interacting protein 3, calsenilin	protein C-terminus binding	Molecular function	-
RC3H2	54542	ring finger and CCCH-type domains 2	cell surface	Cellular component	10938276
RNASE7	84659	ribonuclease, RNase A family, 7	innate immune response	Biological process	12244054
AZIN2	113451	antizyme inhibitor 2	granular vesicle	Cellular component	19718454
ATG2B	55102	autophagy related 2B	pre-autophagosomal structure	Cellular component	-
THEG	51298	theg spermatid protein	nucleus	Cellular component	-
PRPSAP2	5636	phosphoribosyl pyrophosphate synthetase-associated protein 2	bone development	Biological process	-
IGFLR1	79713	IGF-like family receptor 1	integral component of membrane	Cellular component	-
CHIA	27159	chitinase, acidic	immune response	Biological process	11085997
GPX1	2876	glutathione peroxidase 1	negative regulation of release of cytochrome c from mitochondria	Biological process	12221075
SCP2	6342	sterol carrier protein 2	cytoplasm	Cellular component	-
KDM5C	8242	lysine (K)-specific demethylase 5C	DNA binding	Molecular function	-
ST3GAL3	6487	ST3 beta-galactoside alpha-2,3-sialyltransferase 3	glycosaminoglycan metabolic process	Biological process	-
NKIRAS2	28511	NFKB inhibitor interacting Ras-like 2	membrane	Cellular component	-
ATP5A1	498	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle	ATP hydrolysis coupled proton transport	Biological process	-
CD24	100133941	CD24 molecule	anchored component of membrane	Cellular component	-
CDKN2A	1029	cyclin-dependent kinase inhibitor 2A	negative regulation of phosphorylation	Biological process	10208428
CARD8	22900	caspase recruitment domain family, member 8	positive regulation of interleukin-1 beta secretion	Biological process	15030775
SCUBE1	80274	signal peptide, CUB domain, EGF-like 1	extrinsic component of plasma membrane	Cellular component	12270931
ID3	3399	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	cytoplasm	Cellular component	-
F2R	2149	coagulation factor II (thrombin) receptor	negative regulation of renin secretion into blood stream	Biological process	-
GRIN2B	2904	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	N-methyl-D-aspartate selective glutamate receptor complex	Cellular component	10480938
IFT74	80173	intraflagellar transport 74	organelle organization	Biological process	-
CNGB1	1258	cyclic nucleotide gated channel beta 1	protein localization to organelle	Biological process	-
OR13C5	138799	olfactory receptor, family 13, subfamily C, member 5	plasma membrane	Cellular component	-
SMARCA4	6597	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	RNA polymerase II distal enhancer sequence-specific DNA binding	Molecular function	16217013
H2AFX	3014	H2A histone family, member X	positive regulation of DNA repair	Biological process	19234442
LDLRAP1	26119	low density lipoprotein receptor adaptor protein 1	positive regulation of signal transduction	Biological process	12221107
DHX8	1659	DEAH (Asp-Glu-Ala-His) box polypeptide 8	nucleus	Cellular component	7935475
RAD23A	5886	RAD23 homolog A (S. cerevisiae)	proteasome complex	Cellular component	-
PAFAH1B1	5048	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	centrosome	Cellular component	-
TBCD	6904	tubulin folding cofactor D	adherens junction	Cellular component	-
ZNF225	7768	zinc finger protein 225	regulation of transcription, DNA-templated	Biological process	-
CDC42EP5	148170	CDC42 effector protein (Rho GTPase binding) 5	membrane	Cellular component	11035016
EMP1	2012	epithelial membrane protein 1	protein binding	Molecular function	12107182
MEF2A	4205	myocyte enhancer factor 2A	protein kinase binding	Molecular function	-
AQP5	362	aquaporin 5	glycerol transport	Biological process	-
CHD8	57680	chromodomain helicase DNA binding protein 8	positive regulation of transcription from RNA polymerase III promoter	Biological process	17938208
TXN2	25828	thioredoxin 2	neuronal cell body	Cellular component	-
DHX33	56919	DEAH (Asp-Glu-Ala-His) box polypeptide 33	rDNA binding	Molecular function	21930779
FMNL2	114793	formin-like 2	cytosol	Cellular component	-
HIST1H2BL	8340	histone cluster 1, H2bl	nucleoplasm	Cellular component	-
FGA	2243	fibrinogen alpha chain	response to calcium ion	Biological process	6777381
UTRN	7402	utrophin	myofibril	Cellular component	-
ZEB1	6935	zinc finger E-box binding homeobox 1	zinc ion binding	Molecular function	8138542
HOXB3	3213	homeobox B3	thyroid gland development	Biological process	-
MAPK9	5601	mitogen-activated protein kinase 9	positive regulation of chemokine production	Biological process	-
EDNRA	1909	endothelin receptor type A	glucose transport	Biological process	-
CNTROB	116840	centrobin, centrosomal BRCA2 interacting protein	protein binding	Molecular function	16275750
NUP50	10762	nucleoporin 50kDa	nuclear membrane	Cellular component	-
EPRS	2058	glutamyl-prolyl-tRNA synthetase	membrane	Cellular component	19946888
GPAA1	8733	glycosylphosphatidylinositol anchor attachment 1	endoplasmic reticulum membrane	Cellular component	-
PLCG2	5336	phospholipase C, gamma 2 (phosphatidylinositol-specific)	T cell receptor signaling pathway	Biological process	-
LIN7C	55327	lin-7 homolog C (C. elegans)	cell-cell junction	Cellular component	23201090
SLC16A11	162515	solute carrier family 16, member 11	ion transmembrane transport	Biological process	-
RAF1	5894	Raf-1 proto-oncogene, serine/threonine kinase	MAPK cascade	Biological process	-
RNF38	152006	ring finger protein 38	nucleus	Cellular component	23973461
FGF13	2258	fibroblast growth factor 13	positive regulation of protein kinase activity	Biological process	12244047
AQP4	361	aquaporin 4	hyperosmotic salinity response	Biological process	-
OR5M1	390168	olfactory receptor, family 5, subfamily M, member 1	G-protein coupled receptor activity	Molecular function	-
KIF5A	3798	kinesin family member 5A	ATP binding	Molecular function	-
BRCA1	672	breast cancer 1, early onset	protein binding	Molecular function	10477523
SEC61A2	55176	Sec61 alpha 2 subunit (S. cerevisiae)	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	Biological process	-
UBE2V1	7335	ubiquitin-conjugating enzyme E2 variant 1	ubiquitin conjugating enzyme complex	Cellular component	16129784
ADAM15	8751	ADAM metallopeptidase domain 15	adherens junction	Cellular component	-
MTDH	92140	metadherin	transcription coactivator activity	Molecular function	18316612
ZMIZ1	57178	zinc finger, MIZ-type containing 1	transcription, DNA-templated	Biological process	-
GALK1	2584	galactokinase 1	galactokinase activity	Molecular function	12694189
PPAT	5471	phosphoribosyl pyrophosphate amidotransferase	protein homotetramerization	Biological process	-
TPPP	11076	tubulin polymerization promoting protein	microtubule bundle formation	Biological process	-
GEMIN2	8487	gem (nuclear organelle) associated protein 2	gene expression	Biological process	-
MED7	9443	mediator complex subunit 7	regulation of transcription from RNA polymerase II promoter	Biological process	9989412
ARHGAP9	64333	Rho GTPase activating protein 9	protein binding	Molecular function	25416956
VIMP	55829	VCP-interacting membrane selenoprotein	negative regulation of interleukin-6 production	Biological process	-
SIRT5	23408	sirtuin 5	zinc ion binding	Molecular function	22076378
OR5A1	219982	olfactory receptor, family 5, subfamily A, member 1	plasma membrane	Cellular component	-
ARHGAP22	58504	Rho GTPase activating protein 22	positive regulation of GTPase activity	Biological process	-
NIPA2	81614	non imprinted in Prader-Willi/Angelman syndrome 2	magnesium ion transport	Biological process	-
RPL10A	4736	ribosomal protein L10a	cytosolic large ribosomal subunit	Cellular component	12962325
ANXA5	308	annexin A5	calcium-dependent phospholipid binding	Molecular function	2138016
CCK	885	cholecystokinin	protein binding	Molecular function	23597562
ENTPD3	956	ectonucleoside triphosphate diphosphohydrolase 3	nucleoside diphosphate catabolic process	Biological process	-
AK3	50808	adenylate kinase 3	AMP metabolic process	Biological process	11485571
LYRM2	57226	LYR motif containing 2	mitochondrion	Cellular component	-
MAGT1	84061	magnesium transporter 1	post-translational protein modification	Biological process	-
RPS6KA5	9252	ribosomal protein S6 kinase, 90kDa, polypeptide 5	negative regulation of transcription, DNA-templated	Biological process	15010469
PINK1	65018	PTEN induced putative kinase 1	negative regulation of oxidative stress-induced cell death	Biological process	16632486
FITM2	128486	fat storage-inducing transmembrane protein 2	endoplasmic reticulum membrane	Cellular component	18160536
OR1N2	138882	olfactory receptor, family 1, subfamily N, member 2	G-protein coupled receptor signaling pathway	Biological process	-
GALE	2582	UDP-galactose-4-epimerase	UDP-glucose 4-epimerase activity	Molecular function	16302980
WDHD1	11169	WD repeat and HMG-box DNA binding protein 1	RNA binding	Molecular function	-
ADAM11	4185	ADAM metallopeptidase domain 11	metallopeptidase activity	Molecular function	9693107
SPIDR	23514	scaffolding protein involved in DNA repair	regulation of double-strand break repair via homologous recombination	Biological process	23754376
AARSD1	80755	alanyl-tRNA synthetase domain containing 1	alanine-tRNA ligase activity	Molecular function	-
MYH8	4626	myosin, heavy chain 8, skeletal muscle, perinatal	muscle contraction	Biological process	2715179
CRH	1392	corticotropin releasing hormone	hypothalamus development	Biological process	-
SHH	6469	sonic hedgehog	positive regulation of smoothened signaling pathway	Biological process	-
GLUD1	2746	glutamate dehydrogenase 1	substantia nigra development	Biological process	22926577
UCN3	114131	urocortin 3	response to immobilization stress	Biological process	-
UBXN1	51035	UBX domain protein 1	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological process	15362974
SPATA22	84690	spermatogenesis associated 22	chromosome	Cellular component	-
HIST2H3A	333932	histone cluster 2, H3a	histone binding	Molecular function	25615412
CDIP1	29965	cell death-inducing p53 target 1	tumor necrosis factor-mediated signaling pathway	Biological process	17599062
FPGS	2356	folylpolyglutamate synthase	mitochondrion	Cellular component	7721888
SLC51B	123264	solute carrier family 51, beta subunit	regulation of protein stability	Biological process	-
TRIM58	25893	tripartite motif containing 58	zinc ion binding	Molecular function	-
MPST	4357	mercaptopyruvate sulfurtransferase	mitochondrial inner membrane	Cellular component	-
RDH12	145226	retinol dehydrogenase 12 (all-trans/9-cis/11-cis)	protein binding	Molecular function	20006610
PPAP2B	8613	phosphatidic acid phosphatase type 2B	plasma membrane	Cellular component	-
TLE1	7088	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	negative regulation of transcription, DNA-templated	Biological process	9751710
ATP1A1	476	ATPase, Na+/K+ transporting, alpha 1 polypeptide	cellular sodium ion homeostasis	Biological process	10636900
MTERF3	51001	mitochondrial transcription termination factor 3	double-stranded DNA binding	Molecular function	-
HINT1	3094	histidine triad nucleotide binding protein 1	purine ribonucleotide catabolic process	Biological process	16835243
RNF43	54894	ring finger protein 43	ligase activity	Molecular function	-
HDAC6	10013	histone deacetylase 6	core promoter binding	Molecular function	24413532
VAX1	11023	ventral anterior homeobox 1	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
MDM2	4193	MDM2 proto-oncogene, E3 ubiquitin protein ligase	ubiquitin protein ligase binding	Molecular function	18382127
ANXA2	302	annexin A2	phospholipase A2 inhibitor activity	Molecular function	3013422
SLC15A2	6565	solute carrier family 15 (oligopeptide transporter), member 2	drug transport	Biological process	16738539
MYF6	4618	myogenic factor 6 (herculin)	negative regulation of transcription, DNA-templated	Biological process	-
DZIP3	9666	DAZ interacting zinc finger protein 3	poly(A) RNA binding	Molecular function	22658674
SLCO4C1	353189	solute carrier organic anion transporter family, member 4C1	cell differentiation	Biological process	-
MKS1	54903	Meckel syndrome, type 1	cilium morphogenesis	Biological process	-
GREM1	26585	gremlin 1, DAN family BMP antagonist	branching involved in ureteric bud morphogenesis	Biological process	-
DCPS	28960	decapping enzyme, scavenger	nucleoplasm	Cellular component	-
DNAJB9	4189	DnaJ (Hsp40) homolog, subfamily B, member 9	cytoplasm	Cellular component	-
FOSL1	8061	FOS-like antigen 1	sequence-specific DNA binding transcription factor activity	Molecular function	-
KCNA1	3736	potassium channel, voltage gated shaker related subfamily A, member 1	cytoplasmic membrane-bounded vesicle	Cellular component	-
PDGFB	5155	platelet-derived growth factor beta polypeptide	positive chemotaxis	Biological process	21245381
GAS1	2619	growth arrest-specific 1	embryonic cranial skeleton morphogenesis	Biological process	-
KREMEN1	83999	kringle containing transmembrane protein 1	membrane	Cellular component	11267660
KIF23	9493	kinesin family member 23	centrosome	Cellular component	20186884
ECE1	1889	endothelin converting enzyme 1	metal ion binding	Molecular function	-
PLCG1	5335	phospholipase C, gamma 1	calcium ion binding	Molecular function	-
ZNF611	81856	zinc finger protein 611	metal ion binding	Molecular function	-
CAPS	828	calcyphosine	extracellular exosome	Cellular component	23376485
MAPK9	5601	mitogen-activated protein kinase 9	toll-like receptor 2 signaling pathway	Biological process	-
OR7D2	162998	olfactory receptor, family 7, subfamily D, member 2	olfactory receptor activity	Molecular function	-
IGHG1	3500	immunoglobulin heavy constant gamma 1 (G1m marker)	extracellular region	Cellular component	-
UPP1	7378	uridine phosphorylase 1	UMP salvage	Biological process	-
ITGA11	22801	integrin, alpha 11	extracellular matrix organization	Biological process	-
TBX1	6899	T-box 1	lymph vessel development	Biological process	-
ADH7	131	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	retinol binding	Molecular function	9228021
ATP6V1G1	9550	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1	cytosol	Cellular component	-
AKAP8	10270	A kinase (PRKA) anchor protein 8	female pronucleus	Cellular component	-
HOXC11	3227	homeobox C11	metanephros development	Biological process	-
GALNT3	2591	polypeptide N-acetylgalactosaminyltransferase 3	Golgi membrane	Cellular component	-
GATAD1	57798	GATA zinc finger domain containing 1	nucleus	Cellular component	21965549
IL2RB	3560	interleukin 2 receptor, beta	protein binding	Molecular function	23104097
CSK	1445	c-src tyrosine kinase	negative regulation of kinase activity	Biological process	-
HAP1	9001	huntingtin-associated protein 1	lysosome	Cellular component	-
RPS27A	6233	ribosomal protein S27a	translation	Biological process	-
ARL6IP1	23204	ADP-ribosylation factor-like 6 interacting protein 1	protein binding	Molecular function	16189514
SRF	6722	serum response factor (c-fos serum response element-binding transcription factor)	trophectodermal cell differentiation	Biological process	17576768
OTOGL	283310	otogelin-like	sensory perception of sound	Biological process	-
LILRB4	11006	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4	plasma membrane	Cellular component	-
GP1BA	2811	glycoprotein Ib (platelet), alpha polypeptide	integral component of plasma membrane	Cellular component	3353370
GALNT1	2589	polypeptide N-acetylgalactosaminyltransferase 1	Golgi membrane	Cellular component	-
NOSTRIN	115677	nitric oxide synthase trafficking	regulation of nitric-oxide synthase activity	Biological process	-
BCKDHA	593	branched chain keto acid dehydrogenase E1, alpha polypeptide	oxidation-reduction process	Biological process	-
CXCL13	10563	chemokine (C-X-C motif) ligand 13	B cell chemotaxis across high endothelial venule	Biological process	-
TOR1AIP1	26092	torsin A interacting protein 1	protein localization to nucleus	Biological process	-
LSM8	51691	LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae)	protein binding	Molecular function	14667819
IL36A	27179	interleukin 36, alpha	extracellular space	Cellular component	-
EPN1	29924	epsin 1	in utero embryonic development	Biological process	-
TTC8	123016	tetratricopeptide repeat domain 8	renal tubule development	Biological process	-
SUOX	6821	sulfite oxidase	sulfur amino acid catabolic process	Biological process	-
CALM3	808	calmodulin 3 (phosphorylase kinase, delta)	sarcomere	Cellular component	20226167
SSBP2	23635	single-stranded DNA binding protein 2	single-stranded DNA binding	Molecular function	12079286
FAM92A1	137392	family with sequence similarity 92, member A1	protein binding	Molecular function	25416956
ADSL	158	adenylosuccinate lyase	'de novo' AMP biosynthetic process	Biological process	-
TRAPPC12	51112	trafficking protein particle complex 12	vesicle-mediated transport	Biological process	-
PACS1	55690	phosphofurin acidic cluster sorting protein 1	viral process	Biological process	-
IGKV2-40	28916	immunoglobulin kappa variable 2-40	antigen binding	Molecular function	5586923
ANGPT4	51378	angiopoietin 4	receptor tyrosine kinase binding	Molecular function	10051567
PAK6	56924	p21 protein (Cdc42/Rac)-activated kinase 6	cytoplasm	Cellular component	-
AFF3	3899	AF4/FMR2 family, member 3	double-stranded DNA binding	Molecular function	8555498
RPSA	3921	ribosomal protein SA	cell adhesion	Biological process	-
MCC	4163	mutated in colorectal cancers	protein binding	Molecular function	18591935
OR4M2	390538	olfactory receptor, family 4, subfamily M, member 2	G-protein coupled receptor signaling pathway	Biological process	-
PLAUR	5329	plasminogen activator, urokinase receptor	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Biological process	22984561
ZNF607	84775	zinc finger protein 607	regulation of transcription, DNA-templated	Biological process	-
COL5A3	50509	collagen, type V, alpha 3	collagen binding	Molecular function	10722718
DNMT3B	1789	DNA (cytosine-5-)-methyltransferase 3 beta	response to ionizing radiation	Biological process	-
HELB	92797	helicase (DNA) B	ATP-dependent RNA helicase activity	Molecular function	-
UBE2H	7328	ubiquitin-conjugating enzyme E2H	ubiquitin-protein transferase activity	Molecular function	20061386
SORBS1	10580	sorbin and SH3 domain containing 1	actin binding	Molecular function	10085297
ASB15	142685	ankyrin repeat and SOCS box containing 15	intracellular signal transduction	Biological process	-
LEF1	51176	lymphoid enhancer-binding factor 1	steroid hormone mediated signaling pathway	Biological process	18794125
CCT4	10575	chaperonin containing TCP1, subunit 4 (delta)	nucleoplasm	Cellular component	-
TFEC	22797	transcription factor EC	transcription coactivator activity	Molecular function	9256061
ARCN1	372	archain 1	adult locomotory behavior	Biological process	-
DNAJC17	55192	DnaJ (Hsp40) homolog, subfamily C, member 17	cytoplasm	Cellular component	-
RBFOX2	23543	RNA binding protein, fox-1 homolog (C. elegans) 2	poly(A) RNA binding	Molecular function	22658674
SFRP2	6423	secreted frizzled-related protein 2	positive regulation of apoptotic process	Biological process	17848950
OR2G3	81469	olfactory receptor, family 2, subfamily G, member 3	olfactory receptor activity	Molecular function	-
BTRC	8945	beta-transducin repeat containing E3 ubiquitin protein ligase	mitotic cell cycle	Biological process	-
MSRB3	253827	methionine sulfoxide reductase B3	protein binding	Molecular function	25416956
UCP1	7350	uncoupling protein 1 (mitochondrial, proton carrier)	regulation of transcription from RNA polymerase II promoter	Biological process	-
SEPSECS	51091	Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase	transferase activity, transferring selenium-containing groups	Molecular function	-
KIT	3815	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	signal transduction by protein phosphorylation	Biological process	9438854
GPC6	10082	glypican 6	glycosaminoglycan biosynthetic process	Biological process	-
GUCY1A2	2977	guanylate cyclase 1, soluble, alpha 2	GTP binding	Molecular function	-
ARSG	22901	arylsulfatase G	extracellular space	Cellular component	18283100
NEDD4L	23327	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase	plasma membrane	Cellular component	22879586
SULT1A2	6799	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2	flavonol 3-sulfotransferase activity	Molecular function	20056724
PDPN	10630	podoplanin	integral component of plasma membrane	Cellular component	10393083
ARMCX1	51309	armadillo repeat containing, X-linked 1	protein binding	Molecular function	25416956
TARBP2	6895	TAR (HIV-1) RNA binding protein 2	protein homodimerization activity	Molecular function	17452327
POT1	25913	protection of telomeres 1	single-stranded telomeric DNA binding	Molecular function	12768206
ARV1	64801	ARV1 homolog (S. cerevisiae)	regulation of cholesterol metabolic process	Biological process	-
JCHAIN	3512	joining chain of multimeric IgA and IgM	extracellular region	Cellular component	14718574
KAZALD1	81621	Kazal-type serine peptidase inhibitor domain 1	cell differentiation	Biological process	-
TAS2R30	259293	taste receptor, type 2, member 30	bitter taste receptor activity	Molecular function	20022913
TCF21	6943	transcription factor 21	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
CDK6	1021	cyclin-dependent kinase 6	regulation of cell motility	Biological process	16767702
SCYL2	55681	SCY1-like 2 (S. cerevisiae)	endosome to lysosome transport	Biological process	19643732
MCCC1	56922	methylcrotonoyl-CoA carboxylase 1 (alpha)	cytosol	Cellular component	-
ALDH6A1	4329	aldehyde dehydrogenase 6 family, member A1	nucleoplasm	Cellular component	-
ST13P5	144106	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) pseudogene 5	cytoplasm	Cellular component	-
POLR3E	55718	polymerase (RNA) III (DNA directed) polypeptide E (80kD)	nucleus	Cellular component	-
SOD1	6647	superoxide dismutase 1, soluble	cytoplasm	Cellular component	-
NLGN3	54413	neuroligin 3	synapse organization	Biological process	15150161
RIPK1	8737	receptor (TNFRSF)-interacting serine-threonine kinase 1	positive regulation of extrinsic apoptotic signaling pathway	Biological process	21525013
TXNDC9	10190	thioredoxin domain containing 9	cytoplasm	Cellular component	-
PIBF1	10464	progesterone immunomodulatory binding factor 1	protein binding	Molecular function	17500595
ALDH1A2	8854	aldehyde dehydrogenase 1 family, member A2	embryonic camera-type eye development	Biological process	-
ERVK-6	64006	endogenous retrovirus group K, member 6	DNA recombination	Biological process	-
GGT1	2678	gamma-glutamyltransferase 1	arachidonic acid metabolic process	Biological process	-
ARSI	340075	arylsulfatase family, member I	endoplasmic reticulum lumen	Cellular component	-
BAIAP2L2	80115	BAI1-associated protein 2-like 2	vesicle membrane	Cellular component	21743456
FFAR4	338557	free fatty acid receptor 4	negative regulation of inflammatory response	Biological process	-
MTERF4	130916	mitochondrial transcription termination factor 4	cytoplasm	Cellular component	-
RELA	5970	v-rel avian reticuloendotheliosis viral oncogene homolog A	response to organic substance	Biological process	10747850
AR	367	androgen receptor	androgen binding	Molecular function	10075738
SLC25A24	29957	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24	regulation of cell death	Biological process	22015608
AURKB	9212	aurora kinase B	spindle	Cellular component	19774610
HLA-DMA	3108	major histocompatibility complex, class II, DM alpha	chaperone mediated protein folding requiring cofactor	Biological process	-
ZNF440	126070	zinc finger protein 440	regulation of transcription, DNA-templated	Biological process	-
DUSP3	1845	dual specificity phosphatase 3	MyD88-independent toll-like receptor signaling pathway	Biological process	-
CENPT	80152	centromere protein T	mitotic cell cycle	Biological process	-
SLC17A4	10050	solute carrier family 17, member 4	sodium:phosphate symporter activity	Molecular function	10319585
TGFA	7039	transforming growth factor, alpha	growth factor activity	Molecular function	11278323
HDAC3	8841	histone deacetylase 3	nucleus	Cellular component	12711221
EGR1	1958	early growth response 1	cellular response to steroid hormone stimulus	Biological process	-
RCAN1	1827	regulator of calcineurin 1	blood circulation	Biological process	8595418
BAG3	9531	BCL2-associated athanogene 3	cytoplasm	Cellular component	-
SDCCAG8	10806	serologically defined colon cancer antigen 8	cell-cell junction	Cellular component	20835237
CASS4	57091	Cas scaffolding protein family member 4	phosphorelay sensor kinase activity	Molecular function	-
CXCR5	643	chemokine (C-X-C motif) receptor 5	B cell activation	Biological process	-
MESP1	55897	mesoderm posterior basic helix-loop-helix transcription factor 1	cardiac vascular smooth muscle cell differentiation	Biological process	18297060
OR4N4	283694	olfactory receptor, family 4, subfamily N, member 4	G-protein coupled receptor signaling pathway	Biological process	-
MSH3	4437	mutS homolog 3	MutSbeta complex	Cellular component	8942985
ZNF101	94039	zinc finger protein 101	metal ion binding	Molecular function	-
NOTCH1	4851	notch 1	lung development	Biological process	-
ERBB3	2065	erb-b2 receptor tyrosine kinase 3	regulation of cell proliferation	Biological process	11389077
CTRB1	1504	chymotrypsinogen B1	small molecule metabolic process	Biological process	-
CALR3	125972	calreticulin 3	cell differentiation	Biological process	-
ZNF573	126231	zinc finger protein 573	nucleus	Cellular component	-
CYBB	1536	cytochrome b-245, beta polypeptide	Golgi apparatus	Cellular component	-
ABCA1	19	ATP-binding cassette, sub-family A (ABC1), member 1	anion transmembrane transport	Biological process	-
SLIT2	9353	slit homolog 2 (Drosophila)	positive regulation of axonogenesis	Biological process	10197527
MRPL42	28977	mitochondrial ribosomal protein L42	mitochondrial inner membrane	Cellular component	-
MAPK1	5594	mitogen-activated protein kinase 1	synaptic transmission	Biological process	-
WAC	51322	WW domain containing adaptor with coiled-coil	histone H2B conserved C-terminal lysine ubiquitination	Biological process	21329877
CDH13	1012	cadherin 13	regulation of endocytosis	Biological process	17573778
HLA-C	3107	major histocompatibility complex, class I, C	Golgi membrane	Cellular component	-
MYH9	4627	myosin, heavy chain 9, non-muscle	axon guidance	Biological process	-
TFCP2	7024	transcription factor CP2	cellular_component	Cellular component	-
HSP90AB2P	391634	heat shock protein 90kDa alpha (cytosolic), class B member 2, pseudogene	molecular_function	Molecular function	-
CDKN1C	1028	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	neuron maturation	Biological process	-
NOTCH1	4851	notch 1	Notch receptor processing	Biological process	-
TATDN3	128387	TatD DNase domain containing 3	intracellular organelle	Cellular component	-
PAX2	5076	paired box 2	transcription, DNA-templated	Biological process	-
SSTR4	6754	somatostatin receptor 4	G-protein coupled receptor signaling pathway	Biological process	9892014
PRDM13	59336	PR domain containing 13	methyltransferase activity	Molecular function	-
SYNC	81493	syncoilin, intermediate filament protein	Z disc	Cellular component	-
SMN2	6607	survival of motor neuron 2, centromeric	Z disc	Cellular component	-
STEAP4	79689	STEAP family member 4	integral component of plasma membrane	Cellular component	-
CHST15	51363	carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15	chondroitin sulfate metabolic process	Biological process	-
SDF4	51150	stromal cell derived factor 4	plasma membrane	Cellular component	17442889
SOCS2	8835	suppressor of cytokine signaling 2	growth hormone receptor signaling pathway	Biological process	12552091
ANAPC13	25847	anaphase promoting complex subunit 13	anaphase-promoting complex	Cellular component	16364912
SIPA1	6494	signal-induced proliferation-associated 1	intracellular signal transduction	Biological process	9346962
TSPAN32	10077	tetraspanin 32	defense response to protozoan	Biological process	-
TPR	7175	translocated promoter region, nuclear basket protein	biological_process	Biological process	-
CEP135	9662	centrosomal protein 135kDa	cytosol	Cellular component	-
DEGS1	8560	delta(4)-desaturase, sphingolipid 1	oxidation-reduction process	Biological process	-
PRLH	51052	prolactin releasing hormone	prolactin-releasing peptide receptor binding	Molecular function	-
P2RX1	5023	purinergic receptor P2X, ligand gated ion channel, 1	synaptic transmission, glutamatergic	Biological process	-
NPM2	10361	nucleophosmin/nucleoplasmin 2	protein homooligomerization	Biological process	-
ITLN1	55600	intelectin 1 (galactofuranose binding)	positive regulation of glucose import	Biological process	16531507
OR2M7	391196	olfactory receptor, family 2, subfamily M, member 7	olfactory receptor activity	Molecular function	-
EZH2	2146	enhancer of zeste 2 polycomb repressive complex 2 subunit	rhythmic process	Biological process	-
TLR1	7096	toll-like receptor 1	phagocytic vesicle membrane	Cellular component	-
POU2F2	5452	POU class 2 homeobox 2	sequence-specific DNA binding transcription factor activity	Molecular function	-
PSMB4	5692	proteasome (prosome, macropain) subunit, beta type, 4	antigen processing and presentation of peptide antigen via MHC class I	Biological process	-
PRKD1	5587	protein kinase D1	small molecule metabolic process	Biological process	-
MAPK1	5594	mitogen-activated protein kinase 1	toll-like receptor 5 signaling pathway	Biological process	-
FGF12	2257	fibroblast growth factor 12	regulation of sodium ion transmembrane transport	Biological process	12401812
ACAN	176	aggrecan	small molecule metabolic process	Biological process	-
RILPL1	353116	Rab interacting lysosomal protein-like 1	epithelial cell morphogenesis	Biological process	-
DIP2B	57609	DIP2 disco-interacting protein 2 homolog B (Drosophila)	transcription factor binding	Molecular function	-
CCDC64	92558	coiled-coil domain containing 64	neuron projection development	Biological process	-
PGR	5241	progesterone receptor	enzyme binding	Molecular function	12039952
KCTD2	23510	potassium channel tetramerization domain containing 2	protein homooligomerization	Biological process	-
MTMR6	9107	myotubularin related protein 6	cytoplasm	Cellular component	-
RPL7	6129	ribosomal protein L7	protein binding	Molecular function	18274552
PRKAA1	5562	protein kinase, AMP-activated, alpha 1 catalytic subunit	[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity	Molecular function	-
RBMY1F	159163	RNA binding motif protein, Y-linked, family 1, member F	RNA splicing	Biological process	-
PRKDC	5591	protein kinase, DNA-activated, catalytic polypeptide	double-strand break repair	Biological process	-
ADORA3	140	adenosine A3 receptor	plasma membrane	Cellular component	-
INHA	3623	inhibin, alpha	cell surface receptor signaling pathway	Biological process	12456957
MAP1B	4131	microtubule-associated protein 1B	microtubule binding	Molecular function	-
TRMT112	51504	tRNA methyltransferase 11-2 homolog (S. cerevisiae)	protein methyltransferase activity	Molecular function	18539146
IREB2	3658	iron-responsive element binding protein 2	4 iron, 4 sulfur cluster binding	Molecular function	-
ELK1	2002	ELK1, member of ETS oncogene family	toll-like receptor 2 signaling pathway	Biological process	-
RBBP5	5929	retinoblastoma binding protein 5	MLL1 complex	Cellular component	15960975
ZNF559-ZNF177	100529215	ZNF559-ZNF177 readthrough	protein binding	Molecular function	25416956
WDR45B	56270	WD repeat domain 45B	cytosol	Cellular component	-
INSR	3643	insulin receptor	regulation of transcription, DNA-templated	Biological process	12881524
SCCPDH	51097	saccharopine dehydrogenase (putative)	oxidation-reduction process	Biological process	-
EGR1	1958	early growth response 1	cellular response to heparin	Biological process	-
UBE2M	9040	ubiquitin-conjugating enzyme E2M	stimulatory C-type lectin receptor signaling pathway	Biological process	-
BIN2	51411	bridging integrator 2	cell chemotaxis	Biological process	23285027
KDM1A	23028	lysine (K)-specific demethylase 1A	negative regulation of DNA binding	Biological process	17805299
TGS1	96764	trimethylguanosine synthase 1	RNA trimethylguanosine synthase activity	Molecular function	16687569
NF1	4763	neurofibromin 1	negative regulation of neuroblast proliferation	Biological process	-
ADGRE2	30817	adhesion G protein-coupled receptor E2	ruffle membrane	Cellular component	-
THOC5	8563	THO complex 5	stem cell division	Biological process	-
OR1M1	125963	olfactory receptor, family 1, subfamily M, member 1	plasma membrane	Cellular component	-
ZNF124	7678	zinc finger protein 124	protein binding	Molecular function	25416956
UBE2T	29089	ubiquitin-conjugating enzyme E2T	protein K63-linked ubiquitination	Biological process	20061386
TTC14	151613	tetratricopeptide repeat domain 14	nucleic acid binding	Molecular function	-
CSN3	1448	casein kappa	transmembrane transport	Biological process	-
SIX2	10736	SIX homeobox 2	mesenchymal stem cell proliferation	Biological process	-
SMARCA4	6597	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	blastocyst growth	Biological process	-
DAZ4	57135	deleted in azoospermia 4	multicellular organismal development	Biological process	-
TPGS1	91978	tubulin polyglutamylase complex subunit 1	motile cilium	Cellular component	-
ANK3	288	ankyrin 3, node of Ranvier (ankyrin G)	ion channel binding	Molecular function	-
APOA1	335	apolipoprotein A-I	receptor-mediated endocytosis	Biological process	-
NR1H4	9971	nuclear receptor subfamily 1, group H, member 4	positive regulation of transcription from RNA polymerase II promoter	Biological process	21757002
ABLIM3	22885	actin binding LIM protein family, member 3	stress fiber	Cellular component	22684256
NDUFA13	51079	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13	cellular response to retinoic acid	Biological process	17297443
NUP160	23279	nucleoporin 160kDa	small molecule metabolic process	Biological process	-
SLC7A5	8140	solute carrier family 7 (amino acid transporter light chain, L system), member 5	tryptophan transport	Biological process	-
FFAR1	2864	free fatty acid receptor 1	G-protein coupled receptor signaling pathway	Biological process	-
PTEN	5728	phosphatase and tensin homolog	maternal behavior	Biological process	-
TAF1L	138474	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like	viral process	Biological process	-
SFTPC	6440	surfactant protein C	response to growth factor	Biological process	-
SNRPN	6638	small nuclear ribonucleoprotein polypeptide N	cytoplasm	Cellular component	-
BATF3	55509	basic leucine zipper transcription factor, ATF-like 3	transcription from RNA polymerase II promoter	Biological process	10878360
NPM1	4869	nucleophosmin (nucleolar phosphoprotein B23, numatrin)	viral process	Biological process	-
MTHFD1	4522	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase	heart development	Biological process	-
PDK2	5164	pyruvate dehydrogenase kinase, isozyme 2	small molecule metabolic process	Biological process	-
FBXO32	114907	F-box protein 32	nucleolus	Cellular component	-
RHOC	389	ras homolog family member C	cytosol	Cellular component	-
BCL6B	255877	B-cell CLL/lymphoma 6, member B	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
EP300	2033	E1A binding protein p300	protein C-terminus binding	Molecular function	17150957
KLHL20	27252	kelch-like family member 20	actin binding	Molecular function	-
RNF5	6048	ring finger protein 5, E3 ubiquitin protein ligase	protein destabilization	Biological process	-
MDM2	4193	MDM2 proto-oncogene, E3 ubiquitin protein ligase	negative regulation of signal transduction by p53 class mediator	Biological process	16173922
OR6J1	79549	olfactory receptor, family 6, subfamily J, member 1 (gene/pseudogene)	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
DOPEY1	23033	dopey family member 1	protein transport	Biological process	-
VLDLR	7436	very low density lipoprotein receptor	protein binding	Molecular function	10571241
PCSK6	5046	proprotein convertase subtilisin/kexin type 6	extracellular matrix	Cellular component	12535616
KAT2A	2648	K(lysine) acetyltransferase 2A	multicellular organism growth	Biological process	-
ALMS1	7840	Alstrom syndrome protein 1	protein binding	Molecular function	23414517
DERL1	79139	derlin 1	late endosome	Cellular component	-
DCANP1	140947	dendritic cell-associated nuclear protein	nucleus	Cellular component	-
OCA2	4948	oculocutaneous albinism II	melanosome membrane	Cellular component	19116314
COX11	1353	COX11 cytochrome c oxidase copper chaperone	mitochondrial inner membrane	Cellular component	-
TAB3	257397	TGF-beta activated kinase 1/MAP3K7 binding protein 3	I-kappaB kinase/NF-kappaB signaling	Biological process	-
SERPINF1	5176	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1	negative regulation of angiogenesis	Biological process	11562499
CALM1	801	calmodulin 1 (phosphorylase kinase, delta)	activation of phospholipase C activity	Biological process	-
OR52D1	390066	olfactory receptor, family 52, subfamily D, member 1	integral component of membrane	Cellular component	11121057
CDK5	1020	cyclin-dependent kinase 5	positive regulation of neuron apoptotic process	Biological process	-
F7	2155	coagulation factor VII (serum prothrombin conversion accelerator)	calcium ion binding	Molecular function	-
SNAI1	6615	snail family zinc finger 1	nucleus	Cellular component	-
DUSP26	78986	dual specificity phosphatase 26 (putative)	nucleus	Cellular component	15796912
MYD88	4615	myeloid differentiation primary response 88	signal transduction	Biological process	9013863
SSR2	6746	signal sequence receptor, beta (translocon-associated protein beta)	cellular protein metabolic process	Biological process	-
EPHB1	2047	EPH receptor B1	transmembrane-ephrin receptor activity	Molecular function	18034775
PRKACA	5566	protein kinase, cAMP-dependent, catalytic, alpha	cAMP-dependent protein kinase activity	Molecular function	2843813
KCTD10	83892	potassium channel tetramerization domain containing 10	cytoplasm	Cellular component	-
SNAP29	9342	synaptosomal-associated protein, 29kDa	SNARE complex	Cellular component	23217709
NLRC4	58484	NLR family, CARD domain containing 4	cysteine-type endopeptidase inhibitor activity	Molecular function	-
LRRK1	79705	leucine-rich repeat kinase 1	small GTPase mediated signal transduction	Biological process	-
NCAPD2	9918	non-SMC condensin I complex, subunit D2	nucleus	Cellular component	10958694
STX16	8675	syntaxin 16	cytosol	Cellular component	9587053
SFN	2810	stratifin	regulation of epidermal cell division	Biological process	-
SLC35D1	23169	solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1	transmembrane transport	Biological process	-
KAT2B	8850	K(lysine) acetyltransferase 2B	internal peptidyl-lysine acetylation	Biological process	23932781
GRIN2A	2903	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	protein localization	Biological process	-
PIK3R1	5295	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	ErbB-3 class receptor binding	Molecular function	10572067
UBXN7	26043	UBX domain protein 7	protein binding	Molecular function	18775313
PPARA	5465	peroxisome proliferator-activated receptor alpha	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	9748239
FOXP4	116113	forkhead box P4	lung secretory cell differentiation	Biological process	-
RWDD2B	10069	RWD domain containing 2B	biological_process	Biological process	-
BBS9	27241	Bardet-Biedl syndrome 9	molecular_function	Molecular function	-
TAB1	10454	TGF-beta activated kinase 1/MAP3K7 binding protein 1	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	Biological process	-
GSTP1	2950	glutathione S-transferase pi 1	extracellular exosome	Cellular component	19056867
VAMP5	10791	vesicle-associated membrane protein 5	muscle organ development	Biological process	9725904
SMNDC1	10285	survival motor neuron domain containing 1	RNA splicing, via transesterification reactions	Biological process	9731529
ITGA3	3675	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	positive regulation of establishment of protein localization to plasma membrane	Biological process	10455171
GJA1	2697	gap junction protein, alpha 1, 43kDa	multivesicular body	Cellular component	-
KMT2C	58508	lysine (K)-specific methyltransferase 2C	intracellular signal transduction	Biological process	-
ADGRG1	9289	adhesion G protein-coupled receptor G1	G-protein coupled receptor activity	Molecular function	-
OGN	4969	osteoglycin	Golgi lumen	Cellular component	-
NCF2	4688	neutrophil cytosolic factor 2	response to hyperoxia	Biological process	-
CAT	847	catalase	protein homodimerization activity	Molecular function	10656833
MLST8	64223	MTOR associated protein, LST8 homolog (S. cerevisiae)	protein binding	Molecular function	12408816
CTSK	1513	cathepsin K	proteolysis involved in cellular protein catabolic process	Biological process	22952693
PPARA	5465	peroxisome proliferator-activated receptor alpha	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter	Biological process	19955185
TXNL4A	10907	thioredoxin-like 4A	gene expression	Biological process	-
C1orf50	79078	chromosome 1 open reading frame 50	protein binding	Molecular function	25416956
BCAS3	54828	breast carcinoma amplified sequence 3	protein binding	Molecular function	22300583
G6PC	2538	glucose-6-phosphatase, catalytic subunit	urate metabolic process	Biological process	-
GNAO1	2775	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O	muscle contraction	Biological process	9050846
COPE	11316	coatomer protein complex, subunit epsilon	intra-Golgi vesicle-mediated transport	Biological process	-
POLG	5428	polymerase (DNA directed), gamma	mitochondrial nucleoid	Cellular component	18063578
KIF13B	23303	kinesin family member 13B	ATP binding	Molecular function	-
DDB2	1643	damage-specific DNA binding protein 2, 48kDa	UV-damage excision repair	Biological process	22334663
PSMD6	9861	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	viral process	Biological process	-
ASB11	140456	ankyrin repeat and SOCS box containing 11, E3 ubiquitin protein ligase	protein ubiquitination	Biological process	-
NOL8	55035	nucleolar protein 8	DNA replication	Biological process	14660641
DNTT	1791	DNA nucleotidylexotransferase	DNA-directed DNA polymerase activity	Molecular function	-
HNRNPD	3184	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	circadian regulation of translation	Biological process	24423872
TAF5L	27097	TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa	nucleus	Cellular component	-
VAMP7	6845	vesicle-associated membrane protein 7	SNARE binding	Molecular function	-
PRPF4	9128	pre-mRNA processing factor 4	RNA splicing, via transesterification reactions	Biological process	9328476
MYO7A	4647	myosin VIIA	post-embryonic organ morphogenesis	Biological process	-
SOX5	6660	SRY (sex determining region Y)-box 5	cartilage development	Biological process	-
CNFN	84518	cornifelin	extracellular exosome	Cellular component	23376485
AIFM2	84883	apoptosis-inducing factor, mitochondrion-associated, 2	cytosol	Cellular component	11980907
RNF133	168433	ring finger protein 133	ligase activity	Molecular function	-
THBS2	7058	thrombospondin 2	basement membrane	Cellular component	-
IGSF9	57549	immunoglobulin superfamily, member 9	regulation of synapse organization	Biological process	-
AGO4	192670	argonaute RISC catalytic component 4	single-stranded RNA binding	Molecular function	19966796
SIX2	10736	SIX homeobox 2	regulation of ossification	Biological process	-
SLC7A10	56301	solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10	leukocyte migration	Biological process	-
TH	7054	tyrosine hydroxylase	heart development	Biological process	-
CCT6A	908	chaperonin containing TCP1, subunit 6A (zeta 1)	protein folding	Biological process	-
SENP8	123228	SUMO/sentrin specific peptidase family member 8	cytoplasm	Cellular component	-
SF3A2	8175	splicing factor 3a, subunit 2, 66kDa	catalytic step 2 spliceosome	Cellular component	11991638
FGFR2	2263	fibroblast growth factor receptor 2	negative regulation of mitotic nuclear division	Biological process	-
PRKCD	5580	protein kinase C, delta	positive regulation of sphingomyelin catabolic process	Biological process	19279011
PSMB7	5695	proteasome (prosome, macropain) subunit, beta type, 7	proteasome core complex	Cellular component	-
SIX4	51804	SIX homeobox 4	tongue development	Biological process	-
ANK2	287	ankyrin 2, neuronal	ATPase binding	Molecular function	-
RLTPR	146206	RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing	cell migration	Biological process	-
SLC24A1	9187	solute carrier family 24 (sodium/potassium/calcium exchanger), member 1	rhodopsin mediated signaling pathway	Biological process	-
SUPT6H	6830	suppressor of Ty 6 homolog (S. cerevisiae)	poly(A) RNA binding	Molecular function	22658674
MMP7	4316	matrix metallopeptidase 7	response to drug	Biological process	-
MYOF	26509	myoferlin	myoblast fusion	Biological process	-
SIX1	6495	SIX homeobox 1	myoblast migration	Biological process	-
TRIM3	10612	tripartite motif containing 3	early endosome	Cellular component	-
CLDN14	23562	claudin 14	cell junction assembly	Biological process	-
ACTN2	88	actinin, alpha 2	negative regulation of potassium ion transmembrane transporter activity	Biological process	10812072
ENTPD4	9583	ectonucleoside triphosphate diphosphohydrolase 4	cytoplasmic vesicle	Cellular component	-
USP12	219333	ubiquitin specific peptidase 12	protein deubiquitination	Biological process	19075014
ZFP36L1	677	ZFP36 ring finger protein-like 1	cell proliferation	Biological process	-
TFAP2B	7021	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	metanephric nephron development	Biological process	-
PRAMEF9	343070	PRAME family member 9	retinoic acid receptor binding	Molecular function	-
LIMS2	55679	LIM and senescent cell antigen-like domains 2	cell junction assembly	Biological process	-
B3GNT2	10678	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	cellular protein metabolic process	Biological process	-
NACC1	112939	nucleus accumbens associated 1, BEN and BTB (POZ) domain containing	nucleoplasm	Cellular component	-
CLDN7	1366	claudin 7	structural molecule activity	Molecular function	-
ELK3	2004	ELK3, ETS-domain protein (SRF accessory protein 2)	intracellular membrane-bounded organelle	Cellular component	-
PARS2	25973	prolyl-tRNA synthetase 2, mitochondrial (putative)	mitochondrial matrix	Cellular component	-
PRSS53	339105	protease, serine, 53	proteolysis	Biological process	-
SCN8A	6334	sodium channel, voltage gated, type VIII alpha subunit	sodium ion transmembrane transport	Biological process	9828131
NDUFS8	4728	NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)	mitochondrial electron transport, NADH to ubiquinone	Biological process	9666055
CTH	1491	cystathionine gamma-lyase	nucleus	Cellular component	-
AXIN1	8312	axin 1	protein homooligomerization	Biological process	-
CYP4F12	66002	cytochrome P450, family 4, subfamily F, polypeptide 12	integral component of membrane	Cellular component	-
SCN10A	6336	sodium channel, voltage gated, type X alpha subunit	C-fiber	Cellular component	-
LY86	9450	lymphocyte antigen 86	humoral immune response	Biological process	9763566
EIF4ENIF1	56478	eukaryotic translation initiation factor 4E nuclear import factor 1	nucleus	Cellular component	10856257
CD48	962	CD48 molecule	protein binding	Molecular function	12356317
RPS15A	6210	ribosomal protein S15a	cytoplasm	Cellular component	15108328
NUP210	23225	nucleoporin 210kDa	viral process	Biological process	-
FLOT1	10211	flotillin 1	regulation of Rho protein signal transduction	Biological process	-
TMEM245	23731	transmembrane protein 245	integral component of membrane	Cellular component	10564813
SYNDIG1	79953	synapse differentiation inducing 1	cell junction	Cellular component	-
BMP10	27302	bone morphogenetic protein 10	pathway-restricted SMAD protein phosphorylation	Biological process	16049014
APP	351	amyloid beta (A4) precursor protein	visual learning	Biological process	-
CXCL16	58191	chemokine (C-X-C motif) ligand 16	positive regulation of cell migration	Biological process	18373975
PRKAG2	51422	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	protein kinase binding	Molecular function	10698692
CYTH1	9267	cytohesin 1	extrinsic component of cytoplasmic side of plasma membrane	Cellular component	-
CD28	940	CD28 molecule	immunological synapse	Cellular component	-
REXO1	57455	REX1, RNA exonuclease 1 homolog (S. cerevisiae)	nucleoplasm	Cellular component	-
RND1	27289	Rho family GTPase 1	protein binding	Molecular function	10664463
AKTIP	64400	AKT interacting protein	endosome to lysosome transport	Biological process	18799622
ILF3	3609	interleukin enhancer binding factor 3, 90kDa	ribonucleoprotein complex	Cellular component	17289661
UBE2D3	7323	ubiquitin-conjugating enzyme E2D 3	transcription, DNA-templated	Biological process	-
AJUBA	84962	ajuba LIM protein	cellular protein localization	Biological process	-
CYP3A7	1551	cytochrome P450, family 3, subfamily A, polypeptide 7	aromatase activity	Molecular function	-
MLH1	4292	mutL homolog 1	somatic hypermutation of immunoglobulin genes	Biological process	-
IGFBP2	3485	insulin-like growth factor binding protein 2, 36kDa	insulin-like growth factor I binding	Molecular function	19081843
GOT2	2806	glutamic-oxaloacetic transaminase 2, mitochondrial	4-hydroxyproline catabolic process	Biological process	21998747
EPB41L3	23136	erythrocyte membrane protein band 4.1-like 3	plasma membrane	Cellular component	9892180
PPP1CC	5501	protein phosphatase 1, catalytic subunit, gamma isozyme	cleavage furrow	Cellular component	-
UBE2V1	7335	ubiquitin-conjugating enzyme E2 variant 1	toll-like receptor 10 signaling pathway	Biological process	-
CLK3	1198	CDC-like kinase 3	acrosomal vesicle	Cellular component	-
BAX	581	BCL2-associated X protein	cerebral cortex development	Biological process	-
VPS37B	79720	vacuolar protein sorting 37 homolog B (S. cerevisiae)	intracellular transport of virus	Biological process	-
WDR48	57599	WD repeat domain 48	intracellular membrane-bounded organelle	Cellular component	-
STAT6	6778	signal transducer and activator of transcription 6, interleukin-4 induced	signal transducer activity	Molecular function	-
NR2C1	7181	nuclear receptor subfamily 2, group C, member 1	protein binding	Molecular function	12093804
CYP2C18	1562	cytochrome P450, family 2, subfamily C, polypeptide 18	oxygen binding	Molecular function	8110777
PIK3CA	5290	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	phosphatidylinositol-4,5-bisphosphate 3-kinase activity	Molecular function	-
IRF2	3660	interferon regulatory factor 2	nucleoplasm	Cellular component	-
SSTR2	6752	somatostatin receptor 2	somatostatin receptor activity	Molecular function	-
DKK1	22943	dickkopf WNT signaling pathway inhibitor 1	face morphogenesis	Biological process	-
ERCC6L	54821	excision repair cross-complementation group 6-like	cytoplasm	Cellular component	-
KALRN	8997	kalirin, RhoGEF kinase	positive regulation of GTPase activity	Biological process	9285789
CDC6	990	cell division cycle 6	chromatin binding	Molecular function	-
BATF	10538	basic leucine zipper transcription factor, ATF-like	hematopoietic stem cell differentiation	Biological process	-
DNAJB8	165721	DnaJ (Hsp40) homolog, subfamily B, member 8	unfolded protein binding	Molecular function	21231916
MLST8	64223	MTOR associated protein, LST8 homolog (S. cerevisiae)	nucleoplasm	Cellular component	-
GCNT1	2650	glucosaminyl (N-acetyl) transferase 1, core 2	Golgi cisterna	Cellular component	23027862
PSENEN	55851	presenilin enhancer gamma secretase subunit	integral component of plasma membrane	Cellular component	15274632
LANCL2	55915	LanC lantibiotic synthetase component C-like 2 (bacterial)	cytosol	Cellular component	12566319
RPLP0	6175	ribosomal protein, large, P0	structural constituent of ribosome	Molecular function	12962325
F7	2155	coagulation factor VII (serum prothrombin conversion accelerator)	positive regulation of platelet-derived growth factor receptor signaling pathway	Biological process	17991872
CHRNB2	1141	cholinergic receptor, nicotinic, beta 2 (neuronal)	positive regulation of synaptic transmission, dopaminergic	Biological process	-
GFY	100507003	golgi-associated, olfactory signaling regulator	integral component of Golgi membrane	Cellular component	-
MSRB2	22921	methionine sulfoxide reductase B2	zinc ion binding	Molecular function	14699060
SIM2	6493	single-minded family bHLH transcription factor 2	nucleoplasm	Cellular component	-
PSMC3IP	29893	PSMC3 interacting protein	meiotic cell cycle	Biological process	-
HLA-G	3135	major histocompatibility complex, class I, G	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent	Biological process	-
MAVS	57506	mitochondrial antiviral signaling protein	mitochondrial membrane	Cellular component	20451243
MEF2A	4205	myocyte enhancer factor 2A	transcription from RNA polymerase II promoter	Biological process	-
B3GAT1	27087	beta-1,3-glucuronyltransferase 1	small molecule metabolic process	Biological process	-
SHC2	25759	SHC (Src homology 2 domain containing) transforming protein 2	neurotrophin TRK receptor signaling pathway	Biological process	-
SMAD9	4093	SMAD family member 9	positive regulation of cell differentiation	Biological process	-
SLC26A1	10861	solute carrier family 26 (anion exchanger), member 1	3'-phosphoadenosine 5'-phosphosulfate metabolic process	Biological process	-
SOX7	83595	SRY (sex determining region Y)-box 7	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity	Molecular function	-
CNOT6	57472	CCR4-NOT transcription complex, subunit 6	CCR4-NOT complex	Cellular component	19558367
C5orf42	65250	chromosome 5 open reading frame 42	integral component of membrane	Cellular component	-
HESX1	8820	HESX homeobox 1	brain development	Biological process	9620767
GPD1	2819	glycerol-3-phosphate dehydrogenase 1 (soluble)	positive regulation of glycolytic process	Biological process	-
CIB1	10519	calcium and integrin binding 1 (calmyrin)	calcium ion binding	Molecular function	15475008
MCM7	4176	minichromosome maintenance complex component 7	chromatin	Cellular component	8798650
PIK3CA	5290	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	hypomethylation of CpG island	Biological process	-
DAB2IP	153090	DAB2 interacting protein	cell motility involved in cerebral cortex radial glia guided migration	Biological process	-
MTCH1	23787	mitochondrial carrier 1	integral component of membrane	Cellular component	-
MASTL	84930	microtubule associated serine/threonine kinase-like	nucleoplasm	Cellular component	-
EMG1	10436	EMG1 N1-specific pseudouridine methyltransferase	nucleus	Cellular component	-
BBS9	27241	Bardet-Biedl syndrome 9	organelle organization	Biological process	-
TPO	7173	thyroid peroxidase	iodide peroxidase activity	Molecular function	-
RASSF3	283349	Ras association (RalGDS/AF-6) domain family member 3	identical protein binding	Molecular function	20920251
SLC25A10	1468	solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10	cellular nitrogen compound metabolic process	Biological process	-
BCAP31	10134	B-cell receptor-associated protein 31	Sec61 translocon complex	Cellular component	18555783
WNT4	54361	wingless-type MMTV integration site family, member 4	positive regulation of cortisol biosynthetic process	Biological process	16981135
ERCC2	2068	excision repair cross-complementation group 2	protein N-terminus binding	Molecular function	8652557
SKIL	6498	SKI-like proto-oncogene	transcription, DNA-templated	Biological process	-
PEX1	5189	peroxisomal biogenesis factor 1	peroxisome organization	Biological process	11439091
CLDN15	24146	claudin 15	identical protein binding	Molecular function	-
RNF40	9810	ring finger protein 40, E3 ubiquitin protein ligase	protein binding	Molecular function	10944455
DNAJC4	3338	DnaJ (Hsp40) homolog, subfamily C, member 4	membrane	Cellular component	9473517
SLBP	7884	stem-loop binding protein	cytoplasm	Cellular component	15829567
TUBG2	27175	tubulin, gamma 2	GTPase activity	Molecular function	-
RANBP2	5903	RAN binding protein 2	peptidyl-prolyl cis-trans isomerase activity	Molecular function	-
RAB12	201475	RAB12, member RAS oncogene family	endosome to lysosome transport	Biological process	-
CYP2C8	1558	cytochrome P450, family 2, subfamily C, polypeptide 8	xenobiotic metabolic process	Biological process	-
ENY2	56943	enhancer of yellow 2 homolog (Drosophila)	protein transport	Biological process	-
SOD1	6647	superoxide dismutase 1, soluble	response to organic substance	Biological process	12921788
PLA2G4F	255189	phospholipase A2, group IVF	phospholipid metabolic process	Biological process	-
RBMY1B	378948	RNA binding motif protein, Y-linked, family 1, member B	male gonad development	Biological process	9598316
SGMS2	166929	sphingomyelin synthase 2	small molecule metabolic process	Biological process	-
STAB2	55576	stabilin 2	oxidation-reduction process	Biological process	12077138
NPHS1	4868	nephrosis 1, congenital, Finnish type (nephrin)	regulation of excretion	Biological process	-
BCL10	8915	B-cell CLL/lymphoma 10	nucleus	Cellular component	16280327
CLDN8	9073	claudin 8	structural molecule activity	Molecular function	-
KRBOX1	100506243	KRAB box domain containing 1	intracellular	Cellular component	-
NPR1	4881	natriuretic peptide receptor 1	positive regulation of cGMP biosynthetic process	Biological process	-
NUP133	55746	nucleoporin 133kDa	protein transport	Biological process	-
RNGTT	8732	RNA guanylyltransferase and 5'-phosphatase	nucleoplasm	Cellular component	-
SLC5A7	60482	solute carrier family 5 (sodium/choline cotransporter), member 7	transmembrane transport	Biological process	-
VPS28	51160	vacuolar protein sorting 28 homolog (S. cerevisiae)	negative regulation of protein ubiquitination	Biological process	18077552
ATG2A	23130	autophagy related 2A	protein binding	Molecular function	20562859
NME3	4832	NME/NM23 nucleoside diphosphate kinase 3	intracellular	Cellular component	-
HSPA5	3309	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	integral component of endoplasmic reticulum membrane	Cellular component	11181571
CHD8	57680	chromodomain helicase DNA binding protein 8	digestive tract development	Biological process	24998929
EMX1	2016	empty spiracles homeobox 1	nucleus	Cellular component	20887964
RHAG	6005	Rh-associated glycoprotein	ammonium transmembrane transporter activity	Molecular function	11062476
CAPN2	824	calpain 2, (m/II) large subunit	protein heterodimerization activity	Molecular function	-
DYNC2H1	79659	dynein, cytoplasmic 2, heavy chain 1	ATP binding	Molecular function	-
GGA1	26088	golgi-associated, gamma adaptin ear containing, ARF binding protein 1	endosome membrane	Cellular component	-
RIC1	57589	RAB6A GEF complex partner 1	protein complex	Cellular component	23091056
DHX40	79665	DEAH (Asp-Glu-Ala-His) box polypeptide 40	cytoplasm	Cellular component	-
BSN	8927	bassoon presynaptic cytomatrix protein	axon	Cellular component	-
TPD52L2	7165	tumor protein D52-like 2	protein heterodimerization activity	Molecular function	9484778
RNF34	80196	ring finger protein 34, E3 ubiquitin protein ligase	nuclear speck	Cellular component	-
APOA5	116519	apolipoprotein A-V	phosphatidylcholine-sterol O-acyltransferase activator activity	Molecular function	-
LAG3	3902	lymphocyte-activation gene 3	MHC class II protein binding	Molecular function	9159144
ASB11	140456	ankyrin repeat and SOCS box containing 11, E3 ubiquitin protein ligase	intracellular signal transduction	Biological process	-
PLLP	51090	plasmolipin	ion transport	Biological process	-
TNNI3K	51086	TNNI3 interacting kinase	protein binding	Molecular function	12721663
SLIT2	9353	slit homolog 2 (Drosophila)	membrane	Cellular component	16439689
PLCD3	113026	phospholipase C, delta 3	angiogenesis	Biological process	-
MAGEA1	4100	melanoma antigen family A1	plasma membrane	Cellular component	1840703
CCNE2	9134	cyclin E2	cyclin-dependent protein serine/threonine kinase regulator activity	Molecular function	-
TET1	80312	tet methylcytosine dioxygenase 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
ADAMTS13	11093	ADAM metallopeptidase with thrombospondin type 1 motif, 13	integrin binding	Molecular function	11557746
CCBE1	147372	collagen and calcium binding EGF domains 1	positive regulation of vascular endothelial growth factor production	Biological process	24552833
FGF8	2253	fibroblast growth factor 8 (androgen-induced)	mesonephros development	Biological process	18437684
FUT9	10690	fucosyltransferase 9 (alpha (1,3) fucosyltransferase)	fucosyltransferase activity	Molecular function	10386598
CYFIP2	26999	cytoplasmic FMR1 interacting protein 2	neuron projection	Cellular component	-
PARK2	5071	parkin RBR E3 ubiquitin protein ligase	Hsp70 protein binding	Molecular function	12150907
CRELD1	78987	cysteine-rich with EGF-like domains 1	endocardial cushion development	Biological process	18076106
PPBP	5473	pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)	G-protein coupled receptor signaling pathway	Biological process	-
CNOT1	23019	CCR4-NOT transcription complex, subunit 1	gene expression	Biological process	-
DBN1	1627	drebrin 1	actin filament organization	Biological process	-
CENPC	1060	centromere protein C	mitotic cell cycle	Biological process	-
HOMER3	9454	homer scaffolding protein 3	neuronal postsynaptic density	Cellular component	-
UBE2L3	7332	ubiquitin-conjugating enzyme E2L 3	positive regulation of ubiquitin-protein transferase activity	Biological process	12628165
TEK	7010	TEK tyrosine kinase, endothelial	perinuclear region of cytoplasm	Cellular component	-
HDAC3	8841	histone deacetylase 3	histone H3-K9 deacetylation	Biological process	-
BIRC7	79444	baculoviral IAP repeat containing 7	ubiquitin-protein transferase activity	Molecular function	16729033
CIB1	10519	calcium and integrin binding 1 (calmyrin)	positive regulation of establishment of protein localization to plasma membrane	Biological process	20639889
TRPV3	162514	transient receptor potential cation channel, subfamily V, member 3	transmembrane transport	Biological process	-
ASIC2	40	acid sensing (proton gated) ion channel 2	monovalent inorganic cation transport	Biological process	8626462
HDC	3067	histidine decarboxylase	histamine biosynthetic process	Biological process	-
PPP1R12B	4660	protein phosphatase 1, regulatory subunit 12B	positive regulation of catalytic activity	Biological process	9570949
ERI3	79033	ERI1 exoribonuclease family member 3	DNA catabolic process, exonucleolytic	Biological process	-
RGCC	28984	regulator of cell cycle	negative regulation of mitotic cell cycle phase transition	Biological process	17146433
DVL3	1857	dishevelled segment polarity protein 3	planar cell polarity pathway involved in neural tube closure	Biological process	-
APTX	54840	aprataxin	cellular response to DNA damage stimulus	Biological process	15044383
AIM1	202	absent in melanoma 1	biological_process	Biological process	-
FBXL7	23194	F-box and leucine-rich repeat protein 7	G2/M transition of mitotic cell cycle	Biological process	-
BACH2	60468	BTB and CNC homology 1, basic leucine zipper transcription factor 2	RNA polymerase II distal enhancer sequence-specific DNA binding	Molecular function	-
WNK2	65268	WNK lysine deficient protein kinase 2	negative regulation of cell proliferation	Biological process	17667937
JAK2	3717	Janus kinase 2	positive regulation of cytosolic calcium ion concentration	Biological process	-
FAM46D	169966	family with sequence similarity 46, member D	protein binding	Molecular function	25416956
KRT8	3856	keratin 8, type II	viral process	Biological process	-
UNC79	57578	unc-79 homolog (C. elegans)	integral component of membrane	Cellular component	-
SULT4A1	25830	sulfotransferase family 4A, member 1	small molecule metabolic process	Biological process	-
EPHA2	1969	EPH receptor A2	protein binding	Molecular function	10655584
PPP1R12A	4659	protein phosphatase 1, regulatory subunit 12A	contractile fiber	Cellular component	20634291
MS4A2	2206	membrane-spanning 4-domains, subfamily A, member 2	IgE binding	Molecular function	-
TSG101	7251	tumor susceptibility 101	regulation of viral budding via host ESCRT complex	Biological process	18005716
CLEC2D	29121	C-type lectin domain family 2, member D	transmembrane signaling receptor activity	Molecular function	10541800
KCTD6	200845	potassium channel tetramerization domain containing 6	protein binding	Molecular function	25416956
LRRFIP2	9209	leucine rich repeat (in FLII) interacting protein 2	LRR domain binding	Molecular function	10366446
UTS2	10911	urotensin 2	extracellular region	Cellular component	-
TBL1X	6907	transducin (beta)-like 1X-linked	histone deacetylation	Biological process	-
SOD1	6647	superoxide dismutase 1, soluble	mitochondrial intermembrane space	Cellular component	-
FOXA3	3171	forkhead box A3	cellular glucose homeostasis	Biological process	9369482
TXNIP	10628	thioredoxin interacting protein	response to drug	Biological process	-
AKT1	207	v-akt murine thymoma viral oncogene homolog 1	negative regulation of fatty acid beta-oxidation	Biological process	16814735
MYOG	4656	myogenin (myogenic factor 4)	positive regulation of myoblast differentiation	Biological process	-
OR5A2	219981	olfactory receptor, family 5, subfamily A, member 2	G-protein coupled receptor activity	Molecular function	-
MPHOSPH6	10200	M-phase phosphoprotein 6	RNA binding	Molecular function	-
UBB	7314	ubiquitin B	neurotrophin TRK receptor signaling pathway	Biological process	-
SAFB	6294	scaffold attachment factor B	chromatin organization	Biological process	1324173
PIWIL2	55124	piwi-like RNA-mediated gene silencing 2	pi-body	Cellular component	-
FZD8	8325	frizzled class receptor 8	protein binding	Molecular function	22682250
NTRK1	4914	neurotrophic tyrosine kinase, receptor, type 1	transmembrane receptor protein tyrosine kinase activity	Molecular function	15488758
ADGRF4	221393	adhesion G protein-coupled receptor F4	G-protein coupled receptor activity	Molecular function	-
MAGOH	4116	mago-nashi homolog, proliferation-associated (Drosophila)	exon-exon junction complex	Cellular component	16601204
SPIRE2	84501	spire-type actin nucleation factor 2	actin binding	Molecular function	-
ESYT2	57488	extended synaptotagmin-like protein 2	intrinsic component of endoplasmic reticulum membrane	Cellular component	23791178
DDX3X	1654	DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked	eukaryotic translation initiation factor 3 complex	Cellular component	18628297
CSNK1A1L	122011	casein kinase 1, alpha 1-like	protein serine/threonine kinase activity	Molecular function	-
TRPC4AP	26133	transient receptor potential cation channel, subfamily C, member 4 associated protein	calcium ion transmembrane transport	Biological process	-
HLA-DQA1	3117	major histocompatibility complex, class II, DQ alpha 1	immune response	Biological process	3584986
NABP2	79035	nucleic acid binding protein 2	DNA repair	Biological process	18449195
PIK3C3	5289	phosphatidylinositol 3-kinase, catalytic subunit type 3	autophagosome assembly	Biological process	-
NKX2-5	1482	NK2 homeobox 5	transcription from RNA polymerase II promoter	Biological process	-
WDYHV1	55093	WDYHV motif containing 1	protein-N-terminal glutamine amidohydrolase activity	Molecular function	-
PPAP2A	8611	phosphatidic acid phosphatase type 2A	androgen receptor signaling pathway	Biological process	9468526
CDHR4	389118	cadherin-related family member 4	plasma membrane	Cellular component	-
ALOX12	239	arachidonate 12-lipoxygenase	small molecule metabolic process	Biological process	-
SLC22A3	6581	solute carrier family 22 (organic cation transporter), member 3	quaternary ammonium group transport	Biological process	10966924
DYNLT3	6990	dynein, light chain, Tctex-type 3	transport	Biological process	-
PROKR1	10887	prokineticin receptor 1	plasma membrane	Cellular component	-
CAPN1	823	calpain 1, (mu/I) large subunit	receptor catabolic process	Biological process	-
NEO1	4756	neogenin 1	plasma membrane	Cellular component	-
GSX2	170825	GS homeobox 2	regulation of respiratory gaseous exchange by neurological system process	Biological process	-
CAD	790	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	protein autophosphorylation	Biological process	-
SRP14	6727	signal recognition particle 14kDa (homologous Alu RNA binding protein)	extracellular exosome	Cellular component	23376485
DMRT1	1761	doublesex and mab-3 related transcription factor 1	protein heterodimerization activity	Molecular function	-
SLC24A2	25769	solute carrier family 24 (sodium/potassium/calcium exchanger), member 2	calcium ion binding	Molecular function	-
LTA4H	4048	leukotriene A4 hydrolase	poly(A) RNA binding	Molecular function	22658674
B4GALT7	11285	xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7	negative regulation of fibroblast proliferation	Biological process	16583246
RFX6	222546	regulatory factor X, 6	glucose homeostasis	Biological process	20148032
INO80	54617	INO80 complex subunit	spindle assembly	Biological process	20237820
IGSF3	3321	immunoglobulin superfamily, member 3	molecular_function	Molecular function	-
SIRT2	22933	sirtuin 2	response to redox state	Biological process	12887892
JUN	3725	jun proto-oncogene	transforming growth factor beta receptor signaling pathway	Biological process	9732876
FOXO1	2308	forkhead box O1	protein acetylation	Biological process	22510882
CAV1	857	caveolin 1, caveolae protein, 22kDa	enzyme binding	Molecular function	20122998
SLC1A4	6509	solute carrier family 1 (glutamate/neutral amino acid transporter), member 4	activation of mitophagy in response to mitochondrial depolarization	Biological process	22020285
PNKP	11284	polynucleotide kinase 3'-phosphatase	DNA damage response, detection of DNA damage	Biological process	10446193
MYOCD	93649	myocardin	negative regulation of cell proliferation	Biological process	18451334
CLEC7A	64581	C-type lectin domain family 7, member A	integral component of membrane	Cellular component	11567029
INO80	54617	INO80 complex subunit	cellular response to ionizing radiation	Biological process	20687897
ITGB4	3691	integrin, beta 4	G-protein coupled receptor binding	Molecular function	24851274
GLRX	2745	glutaredoxin (thioltransferase)	cytosol	Cellular component	16884690
RIPK1	8737	receptor (TNFRSF)-interacting serine-threonine kinase 1	protein binding	Molecular function	10356400
IMPDH1	3614	IMP (inosine 5'-monophosphate) dehydrogenase 1	cytosol	Cellular component	-
ACAT1	38	acetyl-CoA acetyltransferase 1	metal ion binding	Molecular function	-
KPNA2	3838	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	poly(A) RNA binding	Molecular function	22681889
RAD9A	5883	RAD9 homolog A (S. pombe)	cytoplasm	Cellular component	-
NDUFV1	4723	NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa	mitochondrial respiratory chain complex I	Cellular component	9878551
LCK	3932	LCK proto-oncogene, Src family tyrosine kinase	membrane raft	Cellular component	-
C2	717	complement component 2	response to nutrient	Biological process	-
RAB35	11021	RAB35, member RAS oncogene family	antigen processing and presentation	Biological process	19717423
HDAC5	10014	histone deacetylase 5	cytosol	Cellular component	-
NR3C2	4306	nuclear receptor subfamily 3, group C, member 2	sequence-specific DNA binding	Molecular function	-
DCTD	1635	dCMP deaminase	protein binding	Molecular function	25416956
GATA4	2626	GATA binding protein 4	heart looping	Biological process	-
RRP9	9136	ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)	nucleus	Cellular component	-
LHCGR	3973	luteinizing hormone/choriogonadotropin receptor	ovulation cycle process	Biological process	-
GSX2	170825	GS homeobox 2	hindbrain morphogenesis	Biological process	-
TRAPPC2	6399	trafficking protein particle complex 2	ion channel binding	Molecular function	12681486
CAMLG	819	calcium modulating ligand	integral component of membrane	Cellular component	-
BCL3	602	B-cell CLL/lymphoma 3	transcription, DNA-templated	Biological process	16306601
ZNF217	7764	zinc finger protein 217	protein binding	Molecular function	16940172
LEPROT	54741	leptin receptor overlapping transcript	negative regulation of protein localization to cell surface	Biological process	18042720
LYST	1130	lysosomal trafficking regulator	microtubule-based process	Biological process	-
PLK4	10733	polo-like kinase 4	centriole	Cellular component	16244668
PSMC5	5705	proteasome (prosome, macropain) 26S subunit, ATPase, 5	apoptotic process	Biological process	-
ACOT7	11332	acyl-CoA thioesterase 7	protein binding	Molecular function	10578051
PTPRK	5796	protein tyrosine phosphatase, receptor type, K	negative regulation of transcription, DNA-templated	Biological process	18276111
FASN	2194	fatty acid synthase	poly(A) RNA binding	Molecular function	22658674
KANSL1	284058	KAT8 regulatory NSL complex subunit 1	histone acetyltransferase activity (H4-K8 specific)	Molecular function	20018852
ADD1	118	adducin 1 (alpha)	cellular component disassembly involved in execution phase of apoptosis	Biological process	-
SND1	27044	staphylococcal nuclease and tudor domain containing 1	mitochondrion	Cellular component	-
CSRP3	8048	cysteine and glycine-rich protein 3 (cardiac LIM protein)	structural constituent of muscle	Molecular function	12507422
GLYCAM1	644076	glycosylation dependent cell adhesion molecule 1 (pseudogene)	plasma membrane	Cellular component	-
PXDNL	137902	peroxidasin-like	peroxidase activity	Molecular function	-
HUNK	30811	hormonally up-regulated Neu-associated kinase	protein serine/threonine kinase activity	Molecular function	-
VEGFB	7423	vascular endothelial growth factor B	positive regulation of vascular endothelial growth factor receptor signaling pathway	Biological process	18259607
TCF7L2	6934	transcription factor 7-like 2 (T-cell specific, HMG-box)	regulation of hormone metabolic process	Biological process	15525634
SOX17	64321	SRY (sex determining region Y)-box 17	protein destabilization	Biological process	17875931
CHRM4	1132	cholinergic receptor, muscarinic 4	plasma membrane	Cellular component	-
FOXM1	2305	forkhead box M1	cytoplasm	Cellular component	-
EXD2	55218	exonuclease 3'-5' domain containing 2	nucleus	Cellular component	-
NOTO	344022	notochord homeobox	nucleus	Cellular component	-
PYGL	5836	phosphorylase, glycogen, liver	cytosol	Cellular component	-
TGM3	7053	transglutaminase 3	transferase activity, transferring acyl groups	Molecular function	15193648
CHMP1A	5119	charged multivesicular body protein 1A	protein domain specific binding	Molecular function	17928862
F2	2147	coagulation factor II (thrombin)	calcium ion binding	Molecular function	-
SLC6A1	6529	solute carrier family 6 (neurotransmitter transporter), member 1	response to toxic substance	Biological process	-
AMY1C	278	amylase, alpha 1C (salivary)	alpha-amylase activity	Molecular function	-
NOX5	79400	NADPH oxidase, EF-hand calcium binding domain 5	cytokinesis	Biological process	11483596
GTF2F1	2962	general transcription factor IIF, polypeptide 1, 74kDa	7-methylguanosine mRNA capping	Biological process	-
MRE11A	4361	MRE11 meiotic recombination 11 homolog A (S. cerevisiae)	cellular response to DNA damage stimulus	Biological process	17500065
RPS3	6188	ribosomal protein S3	protein binding	Molecular function	15161933
ACAP1	9744	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1	GTPase activator activity	Molecular function	-
PRSS21	10942	protease, serine, 21 (testisin)	serine-type endopeptidase activity	Molecular function	-
ADGRG2	10149	adhesion G protein-coupled receptor G2	G-protein coupled receptor activity	Molecular function	-
RPGRIP1L	23322	RPGRIP1-like	liver development	Biological process	-
ZBTB24	9841	zinc finger and BTB domain containing 24	metal ion binding	Molecular function	-
MCEMP1	199675	mast cell-expressed membrane protein 1	integral component of membrane	Cellular component	-
KLHL13	90293	kelch-like family member 13	ubiquitin-protein transferase activity	Molecular function	17543862
NKX2-2	4821	NK2 homeobox 2	negative regulation of neuron differentiation	Biological process	-
AARSD1	80755	alanyl-tRNA synthetase domain containing 1	nucleic acid binding	Molecular function	-
CREB3L2	64764	cAMP responsive element binding protein 3-like 2	integral component of membrane	Cellular component	-
APOA1BP	128240	apolipoprotein A-I binding protein	NADP metabolic process	Biological process	-
ADSS	159	adenylosuccinate synthase	aspartate metabolic process	Biological process	-
EPHB1	2047	EPH receptor B1	neurogenesis	Biological process	-
FRMPD4	9758	FERM and PDZ domain containing 4	phosphatidylinositol-4,5-bisphosphate binding	Molecular function	19118189
OOEP	441161	oocyte expressed protein	cell cortex	Cellular component	-
SFRP1	6422	secreted frizzled-related protein 1	positive regulation of non-canonical Wnt signaling pathway	Biological process	19569235
FZD3	7976	frizzled class receptor 3	cytoplasm	Cellular component	19038973
NOTCH2	4853	notch 2	ciliary body morphogenesis	Biological process	-
LPAR1	1902	lysophosphatidic acid receptor 1	myelination	Biological process	-
MIF	4282	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	positive regulation of peptidyl-tyrosine phosphorylation	Biological process	17045821
FHOD3	80206	formin homology 2 domain containing 3	actin filament network formation	Biological process	-
SAP130	79595	Sin3A-associated protein, 130kDa	negative regulation of transcription from RNA polymerase II promoter	Biological process	22783022
A4GNT	51146	alpha-1,4-N-acetylglucosaminyltransferase	acetylglucosaminyltransferase activity	Molecular function	10430883
H2AFB2	474381	H2A histone family, member B2	protein heterodimerization activity	Molecular function	-
CHAF1B	8208	chromatin assembly factor 1, subunit B (p60)	DNA replication-dependent nucleosome assembly	Biological process	14718166
CD40	958	CD40 molecule, TNF receptor superfamily member 5	positive regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	12761501
TACR1	6869	tachykinin receptor 1	response to nicotine	Biological process	-
CDK7	1022	cyclin-dependent kinase 7	androgen receptor binding	Molecular function	15572661
ACVR2B	93	activin A receptor, type IIB	metal ion binding	Molecular function	-
KARS	3735	lysyl-tRNA synthetase	ATP binding	Molecular function	-
GLS	2744	glutaminase	suckling behavior	Biological process	-
EPS8L1	54869	EPS8-like 1	T cell receptor binding	Molecular function	17617578
ACTL6A	86	actin-like 6A	nucleoplasm	Cellular component	-
MTAP	4507	methylthioadenosine phosphorylase	cytoplasm	Cellular component	-
SASH1	23328	SAM and SH3 domain containing 1	regulation of protein K63-linked ubiquitination	Biological process	23776175
FER	2241	fer (fps/fes related) tyrosine kinase	positive regulation of cell proliferation	Biological process	20111072
CYP2E1	1571	cytochrome P450, family 2, subfamily E, polypeptide 1	steroid hydroxylase activity	Molecular function	-
RPL34	6164	ribosomal protein L34	cellular protein metabolic process	Biological process	-
CCKAR	886	cholecystokinin A receptor	peptide binding	Molecular function	-
DNAJA2	10294	DnaJ (Hsp40) homolog, subfamily A, member 2	metal ion binding	Molecular function	-
CREB1	1385	cAMP responsive element binding protein 1	epidermal growth factor receptor signaling pathway	Biological process	-
TMSB4X	7114	thymosin beta 4, X-linked	actin monomer binding	Molecular function	-
GNRH1	2796	gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)	multicellular organismal development	Biological process	2867548
ZNF395	55893	zinc finger protein 395	cytoplasm	Cellular component	-
IL1RAPL1	11141	interleukin 1 receptor accessory protein-like 1	negative regulation of exocytosis	Biological process	12783849
SEMA3A	10371	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	negative chemotaxis	Biological process	-
NUTM1	256646	NUT midline carcinoma, family member 1	cytoplasm	Cellular component	-
KDM4D	55693	lysine (K)-specific demethylase 4D	oxidation-reduction process	Biological process	-
BMP4	652	bone morphogenetic protein 4	pulmonary artery endothelial tube morphogenesis	Biological process	17992660
MYH11	4629	myosin, heavy chain 11, smooth muscle	activation of mitophagy in response to mitochondrial depolarization	Biological process	22020285
ARID3B	10620	AT rich interactive domain 3B (BRIGHT-like)	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
RAB7A	7879	RAB7A, member RAS oncogene family	late endosome	Cellular component	18272684
BAIAP2	10458	BAI1-associated protein 2	nucleoplasm	Cellular component	-
RNASEH2A	10535	ribonuclease H2, subunit A	RNA-DNA hybrid ribonuclease activity	Molecular function	21177858
MAP3K2	10746	mitogen-activated protein kinase kinase kinase 2	ATP binding	Molecular function	-
DOCK6	57572	dedicator of cytokinesis 6	cytoplasm	Cellular component	-
GCNT2	2651	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)	posttranscriptional regulation of gene expression	Biological process	-
XYLB	9942	xylulokinase homolog (H. influenzae)	extracellular exosome	Cellular component	23376485
KCNMB3	27094	potassium channel subfamily M regulatory beta subunit 3	potassium ion transport	Biological process	10692449
FBXO6	26270	F-box protein 6	proteolysis	Biological process	10531035
FSCN1	6624	fascin actin-bundling protein 1	protein binding	Molecular function	15161933
TUBB2A	7280	tubulin, beta 2A class IIa	'de novo' posttranslational protein folding	Biological process	-
RPS6KA2	6196	ribosomal protein S6 kinase, 90kDa, polypeptide 2	MyD88-independent toll-like receptor signaling pathway	Biological process	-
SOHLH1	402381	spermatogenesis and oogenesis specific basic helix-loop-helix 1	ovarian follicle development	Biological process	-
PAICS	10606	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase	membrane	Cellular component	19946888
KPNA1	3836	karyopherin alpha 1 (importin alpha 5)	cellular component disassembly involved in execution phase of apoptosis	Biological process	-
TNS2	23371	tensin 2	intracellular	Cellular component	-
DKK1	22943	dickkopf WNT signaling pathway inhibitor 1	receptor antagonist activity	Molecular function	20723538
IGHMBP2	3508	immunoglobulin mu binding protein 2	DNA helicase activity	Molecular function	8349627
RFX7	64864	regulatory factor X, 7	nucleus	Cellular component	-
ADAL	161823	adenosine deaminase-like	metal ion binding	Molecular function	-
NDRG1	10397	N-myc downstream regulated 1	DNA damage response, signal transduction by p53 class mediator	Biological process	9766676
MED17	9440	mediator complex subunit 17	mediator complex	Cellular component	10198638
PTK2B	2185	protein tyrosine kinase 2 beta	response to drug	Biological process	-
PDLIM3	27295	PDZ and LIM domain 3	Z disc	Cellular component	-
EDN3	1908	endothelin 3	inositol phosphate-mediated signaling	Biological process	1917960
SERPINA5	5104	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5	membrane	Cellular component	7521127
WNT5A	7474	wingless-type MMTV integration site family, member 5A	type B pancreatic cell development	Biological process	-
KLF3	51274	Kruppel-like factor 3 (basic)	sequence-specific DNA binding transcription factor activity	Molecular function	10582345
SLC22A6	9356	solute carrier family 22 (organic anion transporter), member 6	organic anion transmembrane transporter activity	Molecular function	22169006
HSP90AA1	3320	heat shock protein 90kDa alpha (cytosolic), class A member 1	sulfonylurea receptor binding	Molecular function	-
NEDD4L	23327	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase	cytosol	Cellular component	-
AQP2	359	aquaporin 2 (collecting duct)	cellular water homeostasis	Biological process	-
CMTM2	146225	CKLF-like MARVEL transmembrane domain containing 2	nucleoplasm	Cellular component	-
SLC11A2	4891	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2	cellular response to tumor necrosis factor	Biological process	-
CENPE	1062	centromere protein E, 312kDa	mitotic cell cycle	Biological process	-
GLT1D1	144423	glycosyltransferase 1 domain containing 1	transferase activity, transferring glycosyl groups	Molecular function	-
CD70	970	CD70 molecule	extrinsic apoptotic signaling pathway	Biological process	9177220
TSNAX	7257	translin-associated factor X	multicellular organismal development	Biological process	-
RAPGEF6	51735	Rap guanine nucleotide exchange factor (GEF) 6	phosphatidic acid binding	Molecular function	22797597
MON2	23041	MON2 homolog (S. cerevisiae)	trans-Golgi network	Cellular component	-
EIF3L	51386	eukaryotic translation initiation factor 3, subunit L	membrane	Cellular component	19946888
RXFP3	51289	relaxin/insulin-like family peptide receptor 3	G-protein coupled receptor signaling pathway	Biological process	10806363
RC3H2	54542	ring finger and CCCH-type domains 2	B cell homeostasis	Biological process	-
CDC42BPB	9578	CDC42 binding protein kinase beta (DMPK-like)	cytoplasm	Cellular component	-
SPG7	6687	spastic paraplegia 7 (pure and complicated autosomal recessive)	proteolysis	Biological process	-
SDCBP	6386	syndecan binding protein (syntenin)	glycoprotein binding	Molecular function	-
STK32B	55351	serine/threonine kinase 32B	protein phosphorylation	Biological process	-
ADORA1	134	adenosine A1 receptor	cell-cell signaling	Biological process	7818494
ROCK1	6093	Rho-associated, coiled-coil containing protein kinase 1	signal transduction	Biological process	10436159
KIAA0020	9933	KIAA0020	DNA binding	Molecular function	-
XPO5	57510	exportin 5	positive regulation of RNA interference	Biological process	15613540
PTCD3	55037	pentatricopeptide repeat domain 3	regulation of translation	Biological process	-
CD96	10225	CD96 molecule	immune response	Biological process	1313846
FAM170A	340069	family with sequence similarity 170, member A	transcription from RNA polymerase II promoter	Biological process	-
CD79B	974	CD79b molecule, immunoglobulin-associated beta	nucleoplasm	Cellular component	-
GPX1	2876	glutathione peroxidase 1	heart contraction	Biological process	14573732
AGAP11	119385	ankyrin repeat and GTPase domain Arf GTPase activating protein 11	positive regulation of GTPase activity	Biological process	-
TAPT1	202018	transmembrane anterior posterior transformation 1	embryonic skeletal system development	Biological process	-
WDR12	55759	WD repeat domain 12	ribosomal large subunit biogenesis	Biological process	16043514
DDHD2	23259	DDHD domain containing 2	microtubule organizing center	Cellular component	-
SLC46A1	113235	solute carrier family 46 (folate transporter), member 1	heme transport	Biological process	-
SYTL5	94122	synaptotagmin-like 5	intracellular protein transport	Biological process	-
SIGLEC14	100049587	sialic acid binding Ig-like lectin 14	plasma membrane	Cellular component	-
DVL2	1856	dishevelled segment polarity protein 2	protein binding	Molecular function	10644691
SLC39A5	283375	solute carrier family 39 (zinc transporter), member 5	G1 to G0 transition involved in cell differentiation	Biological process	-
CALY	50632	calcyon neuron-specific vesicular protein	clathrin light chain binding	Molecular function	16595675
P2RY8	286530	purinergic receptor P2Y, G-protein coupled, 8	plasma membrane	Cellular component	-
PMM1	5372	phosphomannomutase 1	protein N-linked glycosylation via asparagine	Biological process	-
CCNE1	898	cyclin E1	protein binding	Molecular function	10330164
SLC44A4	80736	solute carrier family 44, member 4	glycerophospholipid biosynthetic process	Biological process	-
DNTTIP1	116092	deoxynucleotidyltransferase, terminal, interacting protein 1	nucleolus	Cellular component	-
KHK	3795	ketohexokinase (fructokinase)	regulation of glycogen metabolic process	Biological process	-
PDE4D	5144	phosphodiesterase 4D, cAMP-specific	T cell receptor signaling pathway	Biological process	17404263
XRN2	22803	5'-3' exoribonuclease 2	5'-3' exonuclease activity	Molecular function	15565158
SLC1A3	6507	solute carrier family 1 (glial high affinity glutamate transporter), member 3	L-glutamate transmembrane transporter activity	Molecular function	7521911
MRPL11	65003	mitochondrial ribosomal protein L11	structural constituent of ribosome	Molecular function	11543634
MOB3C	148932	MOB kinase activator 3C	metal ion binding	Molecular function	-
KIFAP3	22920	kinesin-associated protein 3	extracellular exosome	Cellular component	23376485
DDX1	1653	DEAD (Asp-Glu-Ala-Asp) box helicase 1	double-strand break repair	Biological process	18710941
RGS14	10636	regulator of G-protein signaling 14	termination of G-protein coupled receptor signaling pathway	Biological process	-
CALB1	793	calbindin 1, 28kDa	extracellular exosome	Cellular component	19056867
VARS2	57176	valyl-tRNA synthetase 2, mitochondrial	aminoacyl-tRNA editing activity	Molecular function	-
TCEA1	6917	transcription elongation factor A (SII), 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
FBXO45	200933	F-box protein 45	synapse assembly involved in innervation	Biological process	-
IDNK	414328	idnK, gluconokinase homolog (E. coli)	D-gluconate catabolic process	Biological process	-
ULK3	25989	unc-51 like kinase 3	cellular senescence	Biological process	19279323
DGKE	8526	diacylglycerol kinase, epsilon 64kDa	membrane	Cellular component	19946888
SYNJ1	8867	synaptojanin 1	positive regulation of synaptic vesicle uncoating	Biological process	21563316
MICAL3	57553	microtubule associated monooxygenase, calponin and LIM domain containing 3	actin binding	Molecular function	-
PANX1	24145	pannexin 1	gap junction hemi-channel activity	Molecular function	17715132
WNT5A	7474	wingless-type MMTV integration site family, member 5A	cochlea morphogenesis	Biological process	-
HTATSF1	27336	HIV-1 Tat specific factor 1	regulation of DNA-templated transcription, elongation	Biological process	10454543
SAA4	6291	serum amyloid A4, constitutive	positive chemotaxis	Biological process	-
PEX12	5193	peroxisomal biogenesis factor 12	protein import into peroxisome matrix	Biological process	12456682
PGR	5241	progesterone receptor	ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity	Molecular function	-
VTN	7448	vitronectin	positive regulation of receptor-mediated endocytosis	Biological process	8626514
CASQ2	845	calsequestrin 2 (cardiac muscle)	junctional membrane complex	Cellular component	-
SHH	6469	sonic hedgehog	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation	Biological process	-
TUBB6	84617	tubulin, beta 6 class V	microtubule-based process	Biological process	-
HEY2	23493	hes-related family bHLH transcription factor with YRPW motif 2	nucleus	Cellular component	-
CNOT3	4849	CCR4-NOT transcription complex, subunit 3	regulation of translation	Biological process	-
ETV5	2119	ets variant 5	skeletal muscle acetylcholine-gated channel clustering	Biological process	-
TMEM154	201799	transmembrane protein 154	integral component of membrane	Cellular component	-
RNF19B	127544	ring finger protein 19B	zinc ion binding	Molecular function	-
APOA5	116519	apolipoprotein A-V	lipoprotein metabolic process	Biological process	-
NRBP1	29959	nuclear receptor binding protein 1	membrane	Cellular component	-
GUCD1	83606	guanylyl cyclase domain containing 1	protein binding	Molecular function	25416956
HDAC1	3065	histone deacetylase 1	fungiform papilla formation	Biological process	-
MRPL3	11222	mitochondrial ribosomal protein L3	structural constituent of ribosome	Molecular function	-
Sep-05	5413	septin 5	cytoskeleton	Cellular component	-
CTH	1491	cystathionine gamma-lyase	cysteine metabolic process	Biological process	1339280
ZNF750	79755	zinc finger protein 750	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	22364861
GDI2	2665	GDP dissociation inhibitor 2	Rab GDP-dissociation inhibitor activity	Molecular function	-
AGT	183	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	G-protein coupled receptor signaling pathway	Biological process	10406457
PLIN2	123	perilipin 2	cellular lipid metabolic process	Biological process	-
MYO5A	4644	myosin VA (heavy chain 12, myoxin)	cellular response to insulin stimulus	Biological process	-
BMPR1B	658	bone morphogenetic protein receptor, type IB	positive regulation of bone mineralization	Biological process	18436533
SRF	6722	serum response factor (c-fos serum response element-binding transcription factor)	neuron projection development	Biological process	-
FKBP9	11328	FK506 binding protein 9, 63 kDa	cytoplasm	Cellular component	-
TFRC	7037	transferrin receptor	viral process	Biological process	-
JARID2	3720	jumonji, AT rich interactive domain 2	nucleus	Cellular component	20075857
LHX1	3975	LIM homeobox 1	metanephric part of ureteric bud development	Biological process	-
MET	4233	MET proto-oncogene, receptor tyrosine kinase	axon guidance	Biological process	-
PEX1	5189	peroxisomal biogenesis factor 1	peroxisome	Cellular component	16854980
MEST	4232	mesoderm specific transcript	metabolic process	Biological process	-
UBE2D1	7321	ubiquitin-conjugating enzyme E2D 1	transcription, DNA-templated	Biological process	-
IRAK4	51135	interleukin-1 receptor-associated kinase 4	positive regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	22158417
IL17B	27190	interleukin 17B	inflammatory response	Biological process	-
CUL4A	8451	cullin 4A	negative regulation of cell proliferation	Biological process	8681378
FBF1	85302	Fas (TNFRSF6) binding factor 1	ciliary transition fiber	Cellular component	23348840
ECE1	1889	endothelin converting enzyme 1	endothelin maturation	Biological process	7805846
RPGRIP1L	23322	RPGRIP1-like	embryonic hindlimb morphogenesis	Biological process	-
F5	2153	coagulation factor V (proaccelerin, labile factor)	extracellular vesicle	Cellular component	24769233
CD3E	916	CD3e molecule, epsilon (CD3-TCR complex)	T cell costimulation	Biological process	-
RBCK1	10616	RanBP-type and C3HC4-type zinc finger containing 1	LUBAC complex	Cellular component	17006537
ERP29	10961	endoplasmic reticulum protein 29	smooth endoplasmic reticulum	Cellular component	-
MED30	90390	mediator complex subunit 30	positive regulation of transcription, DNA-templated	Biological process	10198638
RAET1L	154064	retinoic acid early transcript 1L	natural killer cell mediated cytotoxicity	Biological process	-
EHBP1L1	254102	EH domain binding protein 1-like 1	biological_process	Biological process	-
SPCS1	28972	signal peptidase complex subunit 1 homolog (S. cerevisiae)	protein targeting to ER	Biological process	-
LMAN1	3998	lectin, mannose-binding, 1	endoplasmic reticulum-Golgi intermediate compartment	Cellular component	15308636
DNAJB6	10049	DnaJ (Hsp40) homolog, subfamily B, member 6	intermediate filament organization	Biological process	10954706
ZNF830	91603	zinc finger protein 830	chromosome organization	Biological process	-
KEL	3792	Kell blood group, metallo-endopeptidase	skeletal muscle fiber development	Biological process	-
KCNU1	157855	potassium channel, subfamily U, member 1	voltage-gated potassium channel complex	Cellular component	-
MAP2K4	6416	mitogen-activated protein kinase kinase 4	stress-activated MAPK cascade	Biological process	-
UFL1	23376	UFM1-specific ligase 1	ligase activity	Molecular function	-
IGF1	3479	insulin-like growth factor 1 (somatomedin C)	multicellular organism growth	Biological process	-
BRK1	55845	BRICK1, SCAR/WAVE actin-nucleating complex subunit	innate immune response	Biological process	-
CHP1	11261	calcineurin-like EF-hand protein 1	negative regulation of protein phosphorylation	Biological process	-
RORA	6095	RAR-related orphan receptor A	DNA binding	Molecular function	11053433
RNF144B	255488	ring finger protein 144B	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	12853982
CRTAC1	55118	cartilage acidic protein 1	growth cone	Cellular component	-
UGCG	7357	UDP-glucose ceramide glucosyltransferase	sphingolipid metabolic process	Biological process	-
CCBL1	883	cysteine conjugate-beta lyase, cytoplasmic	L-glutamine:pyruvate aminotransferase activity	Molecular function	-
BTRC	8945	beta-transducin repeat containing E3 ubiquitin protein ligase	ligase activity	Molecular function	-
ZSCAN31	64288	zinc finger and SCAN domain containing 31	metal ion binding	Molecular function	-
SIRT7	51547	sirtuin 7	rRNA transcription	Biological process	19174463
HMBS	3145	hydroxymethylbilane synthase	cytosol	Cellular component	-
TMEM47	83604	transmembrane protein 47	molecular_function	Molecular function	-
IRAK1	3654	interleukin-1 receptor-associated kinase 1	heat shock protein binding	Molecular function	-
CTNNA1	1495	catenin (cadherin-associated protein), alpha 1, 102kDa	gap junction assembly	Biological process	-
UGT1A6	54578	UDP glucuronosyltransferase 1 family, polypeptide A6	drug metabolic process	Biological process	20610558
PABPN1	8106	poly(A) binding protein, nuclear 1	cytoplasm	Cellular component	-
CHRNA5	1138	cholinergic receptor, nicotinic, alpha 5 (neuronal)	synaptic transmission	Biological process	9009220
LAMTOR4	389541	late endosomal/lysosomal adaptor, MAPK and MTOR activator 4	intracellular membrane-bounded organelle	Cellular component	-
NOTCH2	4853	notch 2	Notch signaling pathway	Biological process	-
MICAL1	64780	microtubule associated monooxygenase, calponin and LIM domain containing 1	actin binding	Molecular function	21864500
PTEN	5728	phosphatase and tensin homolog	negative regulation of cell size	Biological process	-
SLC6A16	28968	solute carrier family 6, member 16	intracellular	Cellular component	11112352
MTA1	9112	metastasis associated 1	NuRD complex	Cellular component	-
STXBP3	6814	syntaxin binding protein 3	glucose transport	Biological process	-
BIRC6	57448	baculoviral IAP repeat containing 6	spindle pole	Cellular component	18329369
NPM1	4869	nucleophosmin (nucleolar phosphoprotein B23, numatrin)	nucleoplasm	Cellular component	-
CORO1A	11151	coronin, actin binding protein, 1A	phagolysosome assembly	Biological process	12132654
NOX3	50508	NADPH oxidase 3	NADPH oxidase complex	Cellular component	-
DBF4B	80174	DBF4 zinc finger B	zinc ion binding	Molecular function	-
SLC44A4	80736	solute carrier family 44, member 4	plasma membrane	Cellular component	-
LST1	7940	leukocyte specific transcript 1	regulation of cell shape	Biological process	-
YBX3	8531	Y box binding protein 3	transcription corepressor activity	Molecular function	8710501
FOXK2	3607	forkhead box K2	regulation of transcription from RNA polymerase II promoter	Biological process	1909027
CX3CL1	6376	chemokine (C-X3-C motif) ligand 1	neutrophil chemotaxis	Biological process	-
ATP1A4	480	ATPase, Na+/K+ transporting, alpha 4 polypeptide	plasma membrane	Cellular component	-
MTCL1	23255	microtubule crosslinking factor 1	microtubule binding	Molecular function	23902687
CXCL11	6373	chemokine (C-X-C motif) ligand 11	chemokine activity	Molecular function	12782716
CST9LP1	128820	cystatin 9-like pseudogene 1	extracellular region	Cellular component	-
PRKD1	5587	protein kinase D1	peptidyl-serine phosphorylation	Biological process	18440775
CUL5	8065	cullin 5	negative regulation of cell proliferation	Biological process	8681378
VCP	7415	valosin containing protein	error-free translesion synthesis	Biological process	-
CTAG1B	1485	cancer/testis antigen 1B	cytoplasm	Cellular component	-
OR2H2	7932	olfactory receptor, family 2, subfamily H, member 2	G-protein coupled receptor activity	Molecular function	-
KRIT1	889	KRIT1, ankyrin repeat containing	GTPase regulator activity	Molecular function	9285558
NT5C1B	93034	5'-nucleotidase, cytosolic IB	nucleus	Cellular component	21630459
IRAK2	3656	interleukin-1 receptor-associated kinase 2	inflammatory response	Biological process	9374458
GBE1	2632	glucan (1,4-alpha-), branching enzyme 1	hydrolase activity, hydrolyzing O-glycosyl compounds	Molecular function	-
UGT2B4	7363	UDP glucuronosyltransferase 2 family, polypeptide B4	cellular response to hormone stimulus	Biological process	-
SLC4A4	8671	solute carrier family 4 (sodium bicarbonate cotransporter), member 4	transport	Biological process	9235899
SLC1A4	6509	solute carrier family 1 (glutamate/neutral amino acid transporter), member 4	glutamine transport	Biological process	21757002
NUF2	83540	NUF2, NDC80 kinetochore complex component	Ndc80 complex	Cellular component	14699129
TPH2	121278	tryptophan hydroxylase 2	amino acid binding	Molecular function	-
DGKK	139189	diacylglycerol kinase, kappa	cytoplasm	Cellular component	-
TXK	7294	TXK tyrosine kinase	NK T cell differentiation	Biological process	-
ZNF142	7701	zinc finger protein 142	molecular_function	Molecular function	-
TDGF1	6997	teratocarcinoma-derived growth factor 1	cellular response to fibroblast growth factor stimulus	Biological process	17720976
ACE2	59272	angiotensin I converting enzyme 2	plasma membrane	Cellular component	-
UBC	7316	ubiquitin C	toll-like receptor 2 signaling pathway	Biological process	-
CEBPA	1050	CCAAT/enhancer binding protein (C/EBP), alpha	generation of precursor metabolites and energy	Biological process	8643605
SCN11A	11280	sodium channel, voltage gated, type XI alpha subunit	membrane depolarization during action potential	Biological process	-
THY1	7070	Thy-1 cell surface antigen	positive regulation of release of sequestered calcium ion into cytosol	Biological process	-
ACLY	47	ATP citrate lyase	metal ion binding	Molecular function	-
LOC400927-CSNK1E	102800317	LOC400927-CSNK1E readthrough	endocytosis	Biological process	-
SPOP	8405	speckle-type POZ protein	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological process	22085717
RTCB	51493	RNA 2',3'-cyclic phosphate and 5'-OH ligase	cytoplasm	Cellular component	24608264
PNLIPRP1	5407	pancreatic lipase-related protein 1	calcium ion binding	Molecular function	-
KCNJ11	3767	potassium channel, inwardly rectifying subfamily J, member 11	cell body fiber	Cellular component	-
CBX8	57332	chromobox homolog 8	ubiquitin-protein transferase activity	Molecular function	-
CYB561A3	220002	cytochrome b561 family, member A3	integral component of membrane	Cellular component	-
MEF2D	4209	myocyte enhancer factor 2D	osteoblast differentiation	Biological process	-
CCNG1	900	cyclin G1	brain development	Biological process	-
PLXND1	23129	plexin D1	outflow tract morphogenesis	Biological process	-
RAD50	10111	RAD50 homolog (S. cerevisiae)	positive regulation of kinase activity	Biological process	15790808
ILK	3611	integrin-linked kinase	positive regulation of protein kinase B signaling	Biological process	-
TTL	150465	tubulin tyrosine ligase	regulation of axon extension	Biological process	-
LIF	3976	leukemia inhibitory factor	positive regulation of macrophage differentiation	Biological process	7957045
GDF3	9573	growth differentiation factor 3	primitive streak formation	Biological process	-
NGFR	4804	nerve growth factor receptor	positive regulation of odontogenesis of dentin-containing tooth	Biological process	-
SEMA3C	10512	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	response to drug	Biological process	9405678
CBX2	84733	chromobox homolog 2	nucleus	Cellular component	21282530
ALG13	79868	ALG13, UDP-N-acetylglucosaminyltransferase subunit	lipid glycosylation	Biological process	-
AADAT	51166	aminoadipate aminotransferase	tryptophan catabolic process to kynurenine	Biological process	-
SLC9A6	10479	solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6	hydrogen ion transmembrane transport	Biological process	-
HDAC4	9759	histone deacetylase 4	response to interleukin-1	Biological process	19281832
ARL2BP	23568	ADP-ribosylation factor-like 2 binding protein	mitochondrial matrix	Cellular component	-
TRAF7	84231	TNF receptor-associated factor 7, E3 ubiquitin protein ligase	cellular response to interleukin-6	Biological process	-
SRP19	6728	signal recognition particle 19kDa	signal recognition particle, endoplasmic reticulum targeting	Cellular component	18089836
NDP	4693	Norrie disease (pseudoglioma)	sensory perception of sound	Biological process	8298646
LIG4	3981	ligase IV, DNA, ATP-dependent	cellular response to lithium ion	Biological process	-
ZNF622	90441	zinc finger protein 622	intrinsic apoptotic signaling pathway in response to oxidative stress	Biological process	21771788
BCL2L1	598	BCL2-like 1	mitochondrial matrix	Cellular component	-
IPO5	3843	importin 5	NLS-bearing protein import into nucleus	Biological process	-
ZBTB1	22890	zinc finger and BTB domain containing 1	T cell differentiation in thymus	Biological process	-
SCN5A	6331	sodium channel, voltage gated, type V alpha subunit	sodium ion transmembrane transport	Biological process	21895525
CA4	762	carbonic anhydrase IV	basolateral plasma membrane	Cellular component	17409381
DHX9	1660	DEAH (Asp-Glu-Ala-His) box helicase 9	ATP-dependent DNA helicase activity	Molecular function	9111062
PDE10A	10846	phosphodiesterase 10A	cGMP catabolic process	Biological process	-
CFL1	1072	cofilin 1 (non-muscle)	extracellular exosome	Cellular component	19199708
NPTX1	4884	neuronal pentraxin I	transport vesicle	Cellular component	-
SLC34A2	10568	solute carrier family 34 (type II sodium/phosphate cotransporter), member 2	plasma membrane	Cellular component	-
SYNJ2	8871	synaptojanin 2	small molecule metabolic process	Biological process	-
DLST	1743	dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)	lysine catabolic process	Biological process	-
STK24	8428	serine/threonine kinase 24	protein binding	Molecular function	16189514
PHF1	5252	PHD finger protein 1	ESC/E(Z) complex	Cellular component	23273982
CXCL12	6387	chemokine (C-X-C motif) ligand 12	immune response	Biological process	-
MRPL2	51069	mitochondrial ribosomal protein L2	organelle organization	Biological process	-
STAB2	55576	stabilin 2	receptor-mediated endocytosis	Biological process	12077138
FGF20	26281	fibroblast growth factor 20	signal transduction	Biological process	10913340
SLC22A3	6581	solute carrier family 22 (organic cation transporter), member 3	small molecule metabolic process	Biological process	-
MYPN	84665	myopalladin	protein binding	Molecular function	11309420
POLE	5426	polymerase (DNA directed), epsilon, catalytic subunit	nucleotide-excision repair	Biological process	-
ZFHX2	85446	zinc finger homeobox 2	sequence-specific DNA binding	Molecular function	-
KDR	3791	kinase insert domain receptor	cellular response to vascular endothelial growth factor stimulus	Biological process	15215251
PSMD3	5709	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	cellular nitrogen compound metabolic process	Biological process	-
WISP3	8838	WNT1 inducible signaling pathway protein 3	heparin binding	Molecular function	-
MAPK11	5600	mitogen-activated protein kinase 11	mitochondrion organization	Biological process	-
FGF6	2251	fibroblast growth factor 6	fibroblast growth factor receptor signaling pathway	Biological process	-
NR5A2	2494	nuclear receptor subfamily 5, group A, member 2	nucleus	Cellular component	15143342
GRID2	2895	glutamate receptor, ionotropic, delta 2	plasma membrane	Cellular component	-
NPTX1	4884	neuronal pentraxin I	plasma membrane	Cellular component	-
SKA1	220134	spindle and kinetochore associated complex subunit 1	spindle microtubule	Cellular component	17093495
FAT2	2196	FAT atypical cadherin 2	extracellular exosome	Cellular component	19199708
NKD2	85409	naked cuticle homolog 2 (Drosophila)	cytoplasmic membrane-bounded vesicle	Cellular component	-
UTP11L	51118	UTP11-like, U3 small nucleolar ribonucleoprotein (yeast)	small-subunit processome	Cellular component	-
PLOD1	5351	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1	extracellular exosome	Cellular component	19056867
UNKL	64718	unkempt family zinc finger-like	nucleus	Cellular component	-
USP2	9099	ubiquitin specific peptidase 2	cytoplasm	Cellular component	-
NT5C1A	84618	5'-nucleotidase, cytosolic IA	adenosine metabolic process	Biological process	-
POLR2F	5435	polymerase (RNA) II (DNA directed) polypeptide F	DNA-directed RNA polymerase III complex	Cellular component	-
STOM	2040	stomatin	integral component of plasma membrane	Cellular component	1547348
STXBP4	252983	syntaxin binding protein 4	regulation of insulin secretion involved in cellular response to glucose stimulus	Biological process	12855681
LRRK2	120892	leucine-rich repeat kinase 2	regulation of protein kinase A signaling	Biological process	-
HTR1D	3352	5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled	plasma membrane	Cellular component	-
IDE	3416	insulin-degrading enzyme	metalloendopeptidase activity	Molecular function	17051221
FOXL2	668	forkhead box L2	regulation of transcription from RNA polymerase II promoter	Biological process	-
RPUSD3	285367	RNA pseudouridylate synthase domain containing 3	pseudouridine synthesis	Biological process	-
OR14L1P	127617	olfactory receptor, family 14, subfamily L, member 1 pseudogene	G-protein coupled receptor signaling pathway	Biological process	-
PLCB1	23236	phospholipase C, beta 1 (phosphoinositide-specific)	inositol phosphate metabolic process	Biological process	-
SEMA6B	10501	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B	nervous system development	Biological process	-
RND3	390	Rho family GTPase 3	extracellular exosome	Cellular component	23376485
APOA4	337	apolipoprotein A-IV	phospholipid efflux	Biological process	11162594
NANOS1	340719	nanos homolog 1 (Drosophila)	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	Biological process	24736845
LRP8	7804	low density lipoprotein receptor-related protein 8, apolipoprotein e receptor	receptor complex	Cellular component	23382219
ZGLP1	100125288	zinc finger, GATA-like protein 1	sequence-specific DNA binding	Molecular function	-
MAN2A2	4122	mannosidase, alpha, class 2A, member 2	mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity	Molecular function	-
KDM2A	22992	lysine (K)-specific demethylase 2A	histone demethylase activity (H3-K36 specific)	Molecular function	-
ACTB	60	actin, beta	structural constituent of cytoskeleton	Molecular function	6202424
PML	5371	promyelocytic leukemia	cell fate commitment	Biological process	-
SEC24C	9632	SEC24 family member C	post-translational protein modification	Biological process	-
PSEN1	5663	presenilin 1	T cell activation involved in immune response	Biological process	-
OR2L8	391190	olfactory receptor, family 2, subfamily L, member 8 (gene/pseudogene)	plasma membrane	Cellular component	-
BIRC8	112401	baculoviral IAP repeat containing 8	nucleus	Cellular component	-
CASP12	100506742	caspase 12 (gene/pseudogene)	NLRP3 inflammasome complex	Cellular component	-
NCOA7	135112	nuclear receptor coactivator 7	positive regulation of transcription from RNA polymerase II promoter	Biological process	11971969
ISG15	9636	ISG15 ubiquitin-like modifier	protein tag	Molecular function	-
MCCC1	56922	methylcrotonoyl-CoA carboxylase 1 (alpha)	cellular nitrogen compound metabolic process	Biological process	-
CUTC	51076	cutC copper transporter	copper ion binding	Molecular function	16182249
TENM1	10178	teneurin transmembrane protein 1	heparin binding	Molecular function	10341219
PPM1E	22843	protein phosphatase, Mg2+/Mn2+ dependent, 1E	cellular response to drug	Biological process	20801214
ANO6	196527	anoctamin 6	positive regulation of bone mineralization	Biological process	25589784
UBE2E2	7325	ubiquitin-conjugating enzyme E2E 2	protein K11-linked ubiquitination	Biological process	20061386
VPS35	55737	vacuolar protein sorting 35 homolog (S. cerevisiae)	retrograde transport, endosome to plasma membrane	Biological process	20164305
IRAK3	11213	interleukin-1 receptor-associated kinase 3	negative regulation of macrophage cytokine production	Biological process	12150927
PPP2R5B	5526	protein phosphatase 2, regulatory subunit B', beta	protein binding	Molecular function	15380617
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	repressing transcription factor binding	Molecular function	-
ELFN1	392617	extracellular leucine-rich repeat and fibronectin type III domain containing 1	excitatory synapse	Cellular component	-
DUSP7	1849	dual specificity phosphatase 7	inactivation of MAPK activity	Biological process	-
PLEK	5341	pleckstrin	vesicle docking involved in exocytosis	Biological process	-
TRIP13	9319	thyroid hormone receptor interactor 13	male meiosis I	Biological process	-
NRXN3	9369	neurexin 3	transmembrane signaling receptor activity	Molecular function	18923512
ABCC9	10060	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	potassium ion transport	Biological process	8826984
AGTR1	185	angiotensin II receptor, type 1	regulation of inflammatory response	Biological process	1378723
VPS25	84313	vacuolar protein sorting 25 homolog (S. cerevisiae)	membrane organization	Biological process	-
CLDN10	9071	claudin 10	plasma membrane	Cellular component	-
RPL35A	6165	ribosomal protein L35a	cytosol	Cellular component	-
RAF1	5894	Raf-1 proto-oncogene, serine/threonine kinase	mitogen-activated protein kinase kinase binding	Molecular function	-
MAD2L1	4085	MAD2 mitotic arrest deficient-like 1 (yeast)	identical protein binding	Molecular function	16525508
TAF1	6872	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa	nucleoplasm	Cellular component	-
AP4S1	11154	adaptor-related protein complex 4, sigma 1 subunit	membrane organization	Biological process	-
SYNE2	23224	spectrin repeat containing, nuclear envelope 2	actin binding	Molecular function	-
AP3M1	26985	adaptor-related protein complex 3, mu 1 subunit	anterograde axon cargo transport	Biological process	-
TMX3	54495	thioredoxin-related transmembrane protein 3	cell surface	Cellular component	19995400
HAND1	9421	heart and neural crest derivatives expressed 1	mesenchyme development	Biological process	-
RRM2	6241	ribonucleotide reductase M2	protein heterotetramerization	Biological process	-
APOB	338	apolipoprotein B	positive regulation of cholesterol storage	Biological process	19114110
PPP1R3B	79660	protein phosphatase 1, regulatory subunit 3B	protein phosphatase regulator activity	Molecular function	-
RGS7	6000	regulator of G-protein signaling 7	cytosol	Cellular component	-
RPS6	6194	ribosomal protein S6	G1/S transition of mitotic cell cycle	Biological process	-
PRKAA1	5562	protein kinase, AMP-activated, alpha 1 catalytic subunit	apical plasma membrane	Cellular component	-
CCL4	6351	chemokine (C-C motif) ligand 4	positive regulation of natural killer cell chemotaxis	Biological process	7545673
CD4	920	CD4 molecule	protein binding	Molecular function	11113139
CDC14C	168448	cell division cycle 14C	protein tyrosine phosphatase activity	Molecular function	-
MKL2	57496	MKL/myocardin-like 2	sequence-specific DNA binding transcription factor activity	Molecular function	-
CASP6	839	caspase 6, apoptosis-related cysteine peptidase	apoptotic process	Biological process	-
NTN3	4917	netrin 3	Golgi apparatus	Cellular component	-
HSPB6	126393	heat shock protein, alpha-crystallin-related, B6	nucleus	Cellular component	19464326
CABLES1	91768	Cdk5 and Abl enzyme substrate 1	blood coagulation	Biological process	-
ZNF610	162963	zinc finger protein 610	DNA binding	Molecular function	-
TNFAIP1	7126	tumor necrosis factor, alpha-induced protein 1 (endothelial)	negative regulation of Rho protein signal transduction	Biological process	19782033
BIRC2	329	baculoviral IAP repeat containing 2	response to ethanol	Biological process	-
PIAS1	8554	protein inhibitor of activated STAT, 1	JAK-STAT cascade	Biological process	10805787
BMP2	650	bone morphogenetic protein 2	receptor binding	Molecular function	2315314
FPR3	2359	formyl peptide receptor 3	G-protein coupled receptor signaling pathway	Biological process	-
PASK	23178	PAS domain containing serine/threonine kinase	regulation of glucagon secretion	Biological process	-
FAM209A	200232	family with sequence similarity 209, member A	nucleus	Cellular component	21630459
UNC45B	146862	unc-45 homolog B (C. elegans)	cytoplasm	Cellular component	-
MBL2	4153	mannose-binding lectin (protein C) 2, soluble	killing by host of symbiont cells	Biological process	-
HIST1H3E	8353	histone cluster 1, H3e	chromatin organization	Biological process	-
GCNT2	2651	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)	positive regulation of cell migration	Biological process	-
RIPK1	8737	receptor (TNFRSF)-interacting serine-threonine kinase 1	positive regulation of programmed cell death	Biological process	16611992
SLC30A5	64924	solute carrier family 30 (zinc transporter), member 5	secretory granule	Cellular component	10330022
ARX	170302	aristaless related homeobox	globus pallidus development	Biological process	-
NQO1	1728	NAD(P)H dehydrogenase, quinone 1	cytoplasm	Cellular component	-
SORL1	6653	sortilin-related receptor, L(DLR class) A repeats containing	multivesicular body	Cellular component	-
RALA	5898	v-ral simian leukemia viral oncogene homolog A (ras related)	actin cytoskeleton reorganization	Biological process	10051605
HIPK2	28996	homeodomain interacting protein kinase 2	positive regulation of DNA binding	Biological process	-
EIF5A2	56648	eukaryotic translation initiation factor 5A2	endoplasmic reticulum membrane	Cellular component	-
ERC1	23085	ELKS/RAB6-interacting/CAST family member 1	leucine zipper domain binding	Molecular function	15218148
MGLL	11343	monoglyceride lipase	regulation of inflammatory response	Biological process	-
ACTG1	71	actin gamma 1	innate immune response	Biological process	-
OLIG3	167826	oligodendrocyte transcription factor 3	transcription, DNA-templated	Biological process	-
DHODH	1723	dihydroorotate dehydrogenase (quinone)	nucleoplasm	Cellular component	-
COL3A1	1281	collagen, type III, alpha 1	heart development	Biological process	7546986
RAB3IL1	5866	RAB3A interacting protein (rabin3)-like 1	positive regulation of GTPase activity	Biological process	-
OFD1	8481	oral-facial-digital syndrome 1	mitotic cell cycle	Biological process	-
NFKB1	4790	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	protein binding	Molecular function	10023675
RAC3	5881	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	growth cone	Cellular component	16525025
GNGT1	2792	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	plasma membrane	Cellular component	-
SOX9	6662	SRY (sex determining region Y)-box 9	core promoter sequence-specific DNA binding	Molecular function	20530484
STAB2	55576	stabilin 2	scavenger receptor activity	Molecular function	12077138
TNRC6C	57690	trinucleotide repeat containing 6C	fibroblast growth factor receptor signaling pathway	Biological process	-
ATXN3L	92552	ataxin 3-like	exploration behavior	Biological process	-
NFYC	4802	nuclear transcription factor Y, gamma	protein binding	Molecular function	12401788
TBX22	50945	T-box 22	DNA binding	Molecular function	17846996
CEBPE	1053	CCAAT/enhancer binding protein (C/EBP), epsilon	protein homodimerization activity	Molecular function	-
HIST1H2BF	8343	histone cluster 1, H2bf	nucleus	Cellular component	21630459
SLC22A6	9356	solute carrier family 22 (organic anion transporter), member 6	anion transmembrane transport	Biological process	-
PEA15	8682	phosphoprotein enriched in astrocytes 15	response to morphine	Biological process	-
NUMB	8650	numb homolog (Drosophila)	lung epithelial cell differentiation	Biological process	-
KIF3B	9371	kinesin family member 3B	plus-end-directed vesicle transport along microtubule	Biological process	16298999
H2AFY2	55506	H2A histone family, member Y2	positive regulation of keratinocyte differentiation	Biological process	23595991
MMP2	4313	matrix metallopeptidase 2	ephrin receptor signaling pathway	Biological process	-
RAPGEF1	2889	Rap guanine nucleotide exchange factor (GEF) 1	platelet-derived growth factor receptor signaling pathway	Biological process	-
KATNA1	11104	katanin p60 (ATPase containing) subunit A 1	spindle	Cellular component	19261606
DNM1L	10059	dynamin 1-like	mitochondrion	Cellular component	22265414
HOXB4	3214	homeobox B4	definitive hemopoiesis	Biological process	-
CDC42EP1	11135	CDC42 effector protein (Rho GTPase binding) 1	GTPase activator activity	Molecular function	-
UBE2N	7334	ubiquitin-conjugating enzyme E2N	toll-like receptor TLR1:TLR2 signaling pathway	Biological process	-
CATIP	375307	ciliogenesis associated TTC17 interacting protein	actin filament polymerization	Biological process	24475127
GGNBP1	449520	gametogenetin binding protein 1 (pseudogene)	cell differentiation	Biological process	-
GFPT1	2673	glutamine--fructose-6-phosphate transaminase 1	protein homotetramerization	Biological process	-
PITPNM1	9600	phosphatidylinositol transfer protein, membrane-associated 1	cytoplasm	Cellular component	-
TRIM72	493829	tripartite motif containing 72, E3 ubiquitin protein ligase	muscle system process	Biological process	-
RAB11FIP2	22841	RAB11 family interacting protein 2 (class I)	intracellular membrane-bounded organelle	Cellular component	-
ASF1A	25842	anti-silencing function 1A histone chaperone	DNA replication-independent nucleosome assembly	Biological process	14718166
KAT6B	23522	K(lysine) acetyltransferase 6B	nucleosome	Cellular component	10497217
GM2A	2760	GM2 ganglioside activator	oligosaccharide catabolic process	Biological process	-
CCR5	1234	chemokine (C-C motif) receptor 5 (gene/pseudogene)	endosome	Cellular component	10679098
PSEN1	5663	presenilin 1	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
HLA-E	3133	major histocompatibility complex, class I, E	MHC class Ib protein complex	Cellular component	25631937
OXT	5020	oxytocin/neurophysin I prepropeptide	response to ether	Biological process	-
BMP7	655	bone morphogenetic protein 7	positive regulation of bone mineralization	Biological process	18436533
DEGS1	8560	delta(4)-desaturase, sphingolipid 1	integral component of plasma membrane	Cellular component	9188692
FSHR	2492	follicle stimulating hormone receptor	protein binding	Molecular function	15196694
KCNH5	27133	potassium channel, voltage gated eag related subfamily H, member 5	synaptic transmission	Biological process	-
IKZF4	64375	IKAROS family zinc finger 4 (Eos)	transcription, DNA-templated	Biological process	-
XRN2	22803	5'-3' exoribonuclease 2	aggresome	Cellular component	-
P2RY14	9934	purinergic receptor P2Y, G-protein coupled, 14	G-protein coupled purinergic nucleotide receptor activity	Molecular function	-
KLF1	10661	Kruppel-like factor 1 (erythroid)	cellular response to peptide	Biological process	-
INHBC	3626	inhibin, beta C	hormone activity	Molecular function	-
DUSP21	63904	dual specificity phosphatase 21	nucleus	Cellular component	12408986
CFLAR	8837	CASP8 and FADD-like apoptosis regulator	regulation of necroptotic process	Biological process	21737330
BIRC3	330	baculoviral IAP repeat containing 3	positive regulation of protein ubiquitination	Biological process	21931591
GNB1	2782	guanine nucleotide binding protein (G protein), beta polypeptide 1	signal transducer activity	Molecular function	-
PRNP	5621	prion protein	endoplasmic reticulum	Cellular component	-
NFKBID	84807	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta	protein binding	Molecular function	25416956
ACKR1	2532	atypical chemokine receptor 1 (Duffy blood group)	chemokine-mediated signaling pathway	Biological process	-
FGA	2243	fibrinogen alpha chain	platelet alpha granule	Cellular component	6777381
SYT14	255928	synaptotagmin XIV	clathrin binding	Molecular function	-
AURKA	6790	aurora kinase A	perinuclear region of cytoplasm	Cellular component	20531406
IPO9	55705	importin 9	cytoplasm	Cellular component	11823430
RAB4A	5867	RAB4A, member RAS oncogene family	GDP binding	Molecular function	15907487
TNFRSF25	8718	tumor necrosis factor receptor superfamily, member 25	extracellular region	Cellular component	-
NUP98	4928	nucleoporin 98kDa	glucose transport	Biological process	-
SLC16A9	220963	solute carrier family 16, member 9	protein binding	Molecular function	25416956
CXCL13	10563	chemokine (C-X-C motif) ligand 13	protein heterodimerization activity	Molecular function	11708770
TUBA1A	7846	tubulin, alpha 1a	protein domain specific binding	Molecular function	-
MNX1	3110	motor neuron and pancreas homeobox 1	nerve development	Biological process	-
KIF16B	55614	kinesin family member 16B	endosome	Cellular component	17641687
HIST1H2BC	8347	histone cluster 1, H2bc	nuclear nucleosome	Cellular component	-
RNF135	84282	ring finger protein 135	negative regulation of type I interferon production	Biological process	-
TCN2	6948	transcobalamin II	cobalamin binding	Molecular function	16537422
SEC61B	10952	Sec61 beta subunit	antigen processing and presentation of peptide antigen via MHC class I	Biological process	-
DENND1C	79958	DENN/MADD domain containing 1C	Rab guanyl-nucleotide exchange factor activity	Molecular function	20937701
EGR2	1959	early growth response 2	protein export from nucleus	Biological process	-
DIO3	1735	deiodinase, iodothyronine, type III	cellular nitrogen compound metabolic process	Biological process	-
SOX2	6657	SRY (sex determining region Y)-box 2	positive regulation of neuroblast proliferation	Biological process	-
IL12A	3592	interleukin 12A	defense response to protozoan	Biological process	-
PSMD11	5717	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	small molecule metabolic process	Biological process	-
IL15RA	3601	interleukin 15 receptor, alpha	endoplasmic reticulum membrane	Cellular component	-
PPP1R9A	55607	protein phosphatase 1, regulatory subunit 9A	synapse	Cellular component	-
KATNB1	10300	katanin p80 (WD repeat containing) subunit B 1	microtubule	Cellular component	-
ADORA2A	135	adenosine A2a receptor	response to amphetamine	Biological process	-
KIAA1024	23251	KIAA1024	integral component of membrane	Cellular component	-
EME2	197342	essential meiotic structure-specific endonuclease subunit 2	nucleus	Cellular component	-
ARRDC2	27106	arrestin domain containing 2	cytoplasmic vesicle	Cellular component	23236378
G6PD	2539	glucose-6-phosphate dehydrogenase	oxidation-reduction process	Biological process	2420826
HIST1H4F	8361	histone cluster 1, H4f	DNA methylation on cytosine	Biological process	-
MUC2	4583	mucin 2, oligomeric mucus/gel-forming	post-translational protein modification	Biological process	-
ZNF730	100129543	zinc finger protein 730	regulation of transcription, DNA-templated	Biological process	-
RPH3A	22895	rabphilin 3A	syntaxin binding	Molecular function	-
GTSE1	51512	G-2 and S-phase expressed 1	molecular_function	Molecular function	-
CREB3	10488	cAMP responsive element binding protein 3	transcription, DNA-templated	Biological process	9271389
UCN	7349	urocortin	associative learning	Biological process	-
S100A1	6271	S100 calcium binding protein A1	Z disc	Cellular component	-
ERO1LB	56605	ERO1-like beta (S. cerevisiae)	glucose homeostasis	Biological process	-
PAX6	5080	paired box 6	pancreatic A cell development	Biological process	20592023
RPS11	6205	ribosomal protein S11	extracellular exosome	Cellular component	19056867
CYP4A11	1579	cytochrome P450, family 4, subfamily A, polypeptide 11	renal water homeostasis	Biological process	10660572
CTDP1	9150	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1	nucleoplasm	Cellular component	-
B4GALT1	2683	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	Notch signaling pathway	Biological process	-
S100B	6285	S100 calcium binding protein B	learning or memory	Biological process	-
SOX9	6662	SRY (sex determining region Y)-box 9	cochlea morphogenesis	Biological process	-
TACR1	6869	tachykinin receptor 1	angiotensin-mediated drinking behavior	Biological process	-
DLC1	10395	DLC1 Rho GTPase activating protein	focal adhesion assembly	Biological process	-
TRADD	8717	TNFRSF1A-associated via death domain	apoptotic process	Biological process	-
RQCD1	9125	RCD1 required for cell differentiation1 homolog (S. pombe)	regulation of translation	Biological process	-
PKD1L1	168507	polycystic kidney disease 1 like 1	nonmotile primary cilium	Cellular component	24336289
EGFR	1956	epidermal growth factor receptor	Shc-EGFR complex	Cellular component	-
SMURF1	57154	SMAD specific E3 ubiquitin protein ligase 1	protein polyubiquitination	Biological process	19937093
OR1L6	392390	olfactory receptor, family 1, subfamily L, member 6	olfactory receptor activity	Molecular function	-
RBBP4	5928	retinoblastoma binding protein 4	CAF-1 complex	Cellular component	8858152
JUN	3725	jun proto-oncogene	toll-like receptor 2 signaling pathway	Biological process	-
TMEM79	84283	transmembrane protein 79	cuticle development	Biological process	-
SP3	6670	Sp3 transcription factor	metal ion binding	Molecular function	-
SLC44A5	204962	solute carrier family 44, member 5	small molecule metabolic process	Biological process	-
GOT2	2806	glutamic-oxaloacetic transaminase 2, mitochondrial	plasma membrane	Cellular component	9537447
ZFP69B	65243	ZFP69 zinc finger protein B	regulation of transcription, DNA-templated	Biological process	-
HCRT	3060	hypocretin (orexin) neuropeptide precursor	type 1 hypocretin receptor binding	Molecular function	-
SETX	23064	senataxin	axon	Cellular component	21576111
PRAMEF11	440560	PRAME family member 11	negative regulation of apoptotic process	Biological process	-
HIST1H1B	3009	histone cluster 1, H1b	protein stabilization	Biological process	22956909
KIF9	64147	kinesin family member 9	microtubule	Cellular component	21119006
NOS1AP	9722	nitric oxide synthase 1 (neuronal) adaptor protein	inward rectifier potassium channel complex	Cellular component	24665357
DKK3	27122	dickkopf WNT signaling pathway inhibitor 3	negative regulation of cortisol biosynthetic process	Biological process	16981135
ISL1	3670	ISL LIM homeobox 1	positive regulation of cell proliferation	Biological process	-
OR6P1	128366	olfactory receptor, family 6, subfamily P, member 1	sensory perception of smell	Biological process	-
ZNF335	63925	zinc finger protein 335	transcription, DNA-templated	Biological process	-
HENMT1	113802	HEN1 methyltransferase homolog 1 (Arabidopsis)	RNA binding	Molecular function	-
HRASLS2	54979	HRAS-like suppressor 2	transferase activity, transferring acyl groups	Molecular function	-
RCC2	55920	regulator of chromosome condensation 2	positive regulation of G2/M transition of mitotic cell cycle	Biological process	12919680
SLC26A6	65010	solute carrier family 26 (anion exchanger), member 6	chloride transmembrane transport	Biological process	-
GLRB	2743	glycine receptor, beta	nervous system development	Biological process	11929858
RTF1	23168	Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	DNA-templated transcription, initiation	Biological process	-
PTEN	5728	phosphatase and tensin homolog	regulation of cellular component size	Biological process	-
PARP1	142	poly (ADP-ribose) polymerase 1	nucleus	Cellular component	-
SERINC1	57515	serine incorporator 1	sphingolipid metabolic process	Biological process	-
MUL1	79594	mitochondrial E3 ubiquitin protein ligase 1	signal transducer activity	Molecular function	12761501
TGFBR2	7048	transforming growth factor, beta receptor II (70/80kDa)	response to mechanical stimulus	Biological process	-
STUB1	10273	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase	ubiquitin-dependent SMAD protein catabolic process	Biological process	15781469
OR8H3	390152	olfactory receptor, family 8, subfamily H, member 3	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
CASQ1	844	calsequestrin 1 (fast-twitch, skeletal muscle)	sarcoplasmic reticulum lumen	Cellular component	-
P3H2	55214	prolyl 3-hydroxylase 2	basement membrane	Cellular component	-
HAUS7	55559	HAUS augmin-like complex, subunit 7	thioesterase binding	Molecular function	-
YEATS4	8089	YEATS domain containing 4	protein C-terminus binding	Molecular function	10913114
ITPR3	3710	inositol 1,4,5-trisphosphate receptor, type 3	protein heterooligomerization	Biological process	-
NR1H3	10062	nuclear receptor subfamily 1, group H, member 3	negative regulation of macrophage activation	Biological process	-
MSH6	2956	mutS homolog 6	methylated histone binding	Molecular function	23622243
SKI	6497	SKI proto-oncogene	gene expression	Biological process	-
ACTN3	89	actinin, alpha 3 (gene/pseudogene)	integrin binding	Molecular function	8104223
PSEN1	5663	presenilin 1	choline transport	Biological process	-
PDGFRA	5156	platelet-derived growth factor receptor, alpha polypeptide	viral process	Biological process	-
PLN	5350	phospholamban	calcium ion transport	Biological process	-
SRSF5	6430	serine/arginine-rich splicing factor 5	nucleolus	Cellular component	-
PATL1	219988	protein associated with topoisomerase II homolog 1 (yeast)	cytoplasmic mRNA processing body assembly	Biological process	20584987
PTK2B	2185	protein tyrosine kinase 2 beta	membrane raft	Cellular component	-
EHMT2	10919	euchromatic histone-lysine N-methyltransferase 2	chromatin organization	Biological process	-
VCX3A	51481	variable charge, X-linked 3A	nucleolus	Cellular component	-
NOD2	64127	nucleotide-binding oligomerization domain containing 2	positive regulation of epithelial cell proliferation	Biological process	-
USP9X	8239	ubiquitin specific peptidase 9, X-linked	apical part of cell	Cellular component	-
U2AF2	11338	U2 small nuclear RNA auxiliary factor 2	nucleotide binding	Molecular function	-
SYNE3	161176	spectrin repeat containing, nuclear envelope family member 3	LINC complex	Cellular component	18396275
TANC1	85461	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1	myoblast fusion	Biological process	-
SF3A3	10946	splicing factor 3a, subunit 3, 60kDa	protein binding	Molecular function	22190034
MICALL2	79778	MICAL-like 2	neuron projection	Cellular component	-
CPT2	1376	carnitine palmitoyltransferase 2	carnitine shuttle	Biological process	-
NRG1	3084	neuregulin 1	nervous system development	Biological process	17432114
DBF4	10926	DBF4 zinc finger	DNA replication	Biological process	-
NCMAP	400746	noncompact myelin associated protein	structural constituent of myelin sheath	Molecular function	-
CMTM5	116173	CKLF-like MARVEL transmembrane domain containing 5	negative regulation of myoblast differentiation	Biological process	-
AQP6	363	aquaporin 6, kidney specific	water transport	Biological process	-
PTH	5741	parathyroid hormone	hormone activity	Molecular function	-
NEK7	140609	NIMA-related kinase 7	spindle pole	Cellular component	-
NLGN4Y	22829	neuroligin 4, Y-linked	cell surface	Cellular component	-
ADH5	128	alcohol dehydrogenase 5 (class III), chi polypeptide	mitochondrion	Cellular component	-
NKD2	85409	naked cuticle homolog 2 (Drosophila)	lateral plasma membrane	Cellular component	20177058
TRABD2B	388630	TraB domain containing 2B	proteolysis	Biological process	-
VANGL1	81839	VANGL planar cell polarity protein 1	lateral plasma membrane	Cellular component	-
NAMPT	10135	nicotinamide phosphoribosyltransferase	drug binding	Molecular function	-
ST8SIA6	338596	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6	carbohydrate biosynthetic process	Biological process	11980897
MAT2A	4144	methionine adenosyltransferase II, alpha	methionine adenosyltransferase complex	Cellular component	10644686
PI4K2A	55361	phosphatidylinositol 4-kinase type 2 alpha	activation of mitophagy in response to mitochondrial depolarization	Biological process	22020285
IL2RA	3559	interleukin 2 receptor, alpha	integral component of membrane	Cellular component	-
FOSL1	8061	FOS-like antigen 1	response to virus	Biological process	8230424
DNASE2	1777	deoxyribonuclease II, lysosomal	apoptotic DNA fragmentation	Biological process	-
CNOT6	57472	CCR4-NOT transcription complex, subunit 6	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	Biological process	-
SLC9B1	150159	solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1	hydrogen ion transmembrane transport	Biological process	-
TYRO3	7301	TYRO3 protein tyrosine kinase	negative regulation of inflammatory response	Biological process	-
PIR	8544	pirin (iron-binding nuclear protein)	quercetin 2,3-dioxygenase activity	Molecular function	15951572
POLR2E	5434	polymerase (RNA) II (DNA directed) polypeptide E, 25kDa	positive regulation of viral transcription	Biological process	-
ATP1B2	482	ATPase, Na+/K+ transporting, beta 2 polypeptide	ion transmembrane transport	Biological process	-
BNIP3	664	BCL2/adenovirus E1B 19kDa interacting protein 3	positive regulation of protein complex disassembly	Biological process	20436456
ABL1	25	ABL proto-oncogene 1, non-receptor tyrosine kinase	cell leading edge	Cellular component	-
HIF1A	3091	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	glucose homeostasis	Biological process	-
PSMD2	5708	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	negative regulation of canonical Wnt signaling pathway	Biological process	-
NSMF	26012	NMDA receptor synaptonuclear signaling and neuronal migration factor	positive regulation of protein dephosphorylation	Biological process	-
GLRX2	51022	glutaredoxin 2	nucleoplasm	Cellular component	-
SYT8	90019	synaptotagmin VIII	calcium-dependent phospholipid binding	Molecular function	-
SIAH2	6478	siah E3 ubiquitin protein ligase 2	nucleoplasm	Cellular component	-
SPRR2F	6705	small proline-rich protein 2F	cytoplasm	Cellular component	-
LIPT2	387787	lipoyl(octanoyl) transferase 2 (putative)	lipoyl(octanoyl) transferase activity	Molecular function	-
TICRR	90381	TOPBP1-interacting checkpoint and replication regulator	nucleoplasm	Cellular component	-
SMUG1	23583	single-strand-selective monofunctional uracil-DNA glycosylase 1	base-excision repair, AP site formation	Biological process	-
OR51T1	401665	olfactory receptor, family 51, subfamily T, member 1	G-protein coupled receptor activity	Molecular function	-
ATP5G1	516	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)	proton-transporting ATP synthase complex, coupling factor F(o)	Cellular component	-
GPR143	4935	G protein-coupled receptor 143	melanosome organization	Biological process	19717472
TRAPPC2L	51693	trafficking protein particle complex 2-like	Golgi apparatus	Cellular component	-
TRUB2	26995	TruB pseudouridine (psi) synthase family member 2	pseudouridine synthesis	Biological process	-
SIK3	23387	SIK family kinase 3	cytoplasm	Cellular component	-
PSMC3	5702	proteasome (prosome, macropain) 26S subunit, ATPase, 3	negative regulation of canonical Wnt signaling pathway	Biological process	-
CHUK	1147	conserved helix-loop-helix ubiquitous kinase	T cell receptor signaling pathway	Biological process	-
SREBF2	6721	sterol regulatory element binding transcription factor 2	positive regulation of transcription from RNA polymerase II promoter	Biological process	12242332
MIA3	375056	melanoma inhibitory activity family, member 3	endoplasmic reticulum membrane	Cellular component	19269366
FTSJ1	24140	FtsJ RNA methyltransferase homolog 1 (E. coli)	tRNA methyltransferase activity	Molecular function	-
S100A9	6280	S100 calcium binding protein A9	peptidyl-cysteine S-trans-nitrosylation	Biological process	25417112
FBXO7	25793	F-box protein 7	negative regulation of cyclin-dependent protein serine/threonine kinase activity	Biological process	-
TPH2	121278	tryptophan hydroxylase 2	small molecule metabolic process	Biological process	-
WBSCR22	114049	Williams Beuren syndrome chromosome region 22	chromatin modification	Biological process	-
FNTB	2342	farnesyltransferase, CAAX box, beta	protein farnesyltransferase complex	Cellular component	16893176
TBC1D2B	23102	TBC1 domain family, member 2B	regulation of cilium assembly	Biological process	17646400
RPS25	6230	ribosomal protein S25	poly(A) RNA binding	Molecular function	22681889
ASB5	140458	ankyrin repeat and SOCS box containing 5	intracellular	Cellular component	-
KLK6	5653	kallikrein-related peptidase 6	hormone metabolic process	Biological process	11668196
ATCAY	85300	ataxia, cerebellar, Cayman type	cell junction	Cellular component	-
ZNF717	100131827	zinc finger protein 717	metal ion binding	Molecular function	-
SPOCK1	6695	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1	regulation of cell growth	Biological process	8389704
IFNL3	282617	interferon, lambda 3	JAK-STAT cascade	Biological process	-
SLC7A9	11136	solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9	integral component of plasma membrane	Cellular component	10471498
ZEB2	9839	zinc finger E-box binding homeobox 2	positive regulation of melanin biosynthetic process	Biological process	24769727
DRD2	1813	dopamine receptor D2	axonogenesis	Biological process	-
SLC47A2	146802	solute carrier family 47 (multidrug and toxin extrusion), member 2	drug transmembrane transport	Biological process	-
RFX4	5992	regulatory factor X, 4 (influences HLA class II expression)	cilium assembly	Biological process	-
CLCA1	1179	chloride channel accessory 1	cellular response to hypoxia	Biological process	-
FGF4	2249	fibroblast growth factor 4	extracellular region	Cellular component	-
RPL38	6169	ribosomal protein L38	gene expression	Biological process	-
PTX3	5806	pentraxin 3, long	response to yeast	Biological process	-
MED22	6837	mediator complex subunit 22	mediator complex	Cellular component	14638676
ADHFE1	137872	alcohol dehydrogenase, iron containing, 1	small molecule metabolic process	Biological process	-
HDAC2	3066	histone deacetylase 2	dendrite development	Biological process	-
ERP29	10961	endoplasmic reticulum protein 29	protein binding	Molecular function	22665516
TIGD5	84948	tigger transposable element derived 5	nucleus	Cellular component	-
KRT4	3851	keratin 4, type II	intermediate filament cytoskeleton	Cellular component	21371075
STX1A	6804	syntaxin 1A (brain)	synaptic vesicle docking	Biological process	-
SLC30A2	7780	solute carrier family 30 (zinc transporter), member 2	cation transmembrane transport	Biological process	-
MC2R	4158	melanocortin 2 receptor (adrenocorticotropic hormone)	corticotropin receptor activity	Molecular function	-
DEFB104A	140596	defensin, beta 104A	extracellular region	Cellular component	-
HIPK2	28996	homeodomain interacting protein kinase 2	PML body	Cellular component	14647468
USP2	9099	ubiquitin specific peptidase 2	protein binding	Molecular function	16189514
AURKB	9212	aurora kinase B	mitotic spindle midzone assembly	Biological process	19774610
CLDN22	53842	claudin 22	structural molecule activity	Molecular function	-
SWSAP1	126074	SWIM-type zinc finger 7 associated protein 1	protein binding	Molecular function	21965664
DCLRE1A	9937	DNA cross-link repair 1A	nucleic acid phosphodiester bond hydrolysis	Biological process	22692201
APOBEC1	339	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	zinc ion binding	Molecular function	-
LAT	27040	linker for activation of T cells	protein kinase binding	Molecular function	12186560
SPTBN2	6712	spectrin, beta, non-erythrocytic 2	axon guidance	Biological process	-
CCL21	6366	chemokine (C-C motif) ligand 21	positive regulation of glycoprotein biosynthetic process	Biological process	-
TET1	80312	tet methylcytosine dioxygenase 1	chromatin modification	Biological process	-
ELMOD1	55531	ELMO/CED-12 domain containing 1	regulation of protein stability	Biological process	24270810
SRF	6722	serum response factor (c-fos serum response element-binding transcription factor)	neuron development	Biological process	17200232
SLBP	7884	stem-loop binding protein	nucleus	Cellular component	15829567
MEOX1	4222	mesenchyme homeobox 1	sclerotome development	Biological process	-
SLC13A5	284111	solute carrier family 13 (sodium-dependent citrate transporter), member 5	citrate transport	Biological process	-
TUBA3D	113457	tubulin, alpha 3d	'de novo' posttranslational protein folding	Biological process	-
TBXA2R	6915	thromboxane A2 receptor	integral component of plasma membrane	Cellular component	1825698
ATP1B3	483	ATPase, Na+/K+ transporting, beta 3 polypeptide	transmembrane transport	Biological process	-
ACSL3	2181	acyl-CoA synthetase long-chain family member 3	long-chain fatty acid metabolic process	Biological process	20219900
NEUROD1	4760	neuronal differentiation 1	chromatin binding	Molecular function	-
KLF12	11278	Kruppel-like factor 12	RNA polymerase II regulatory region sequence-specific DNA binding	Molecular function	-
SLC6A3	6531	solute carrier family 6 (neurotransmitter transporter), member 3	cation transmembrane transport	Biological process	15505207
Mar-05	54708	membrane-associated ring finger (C3HC4) 5	endoplasmic reticulum membrane	Cellular component	14722266
SLIT2	9353	slit homolog 2 (Drosophila)	identical protein binding	Molecular function	19498462
NKX2-2	4821	NK2 homeobox 2	transcription coactivator activity	Molecular function	-
HSD17B1	3292	hydroxysteroid (17-beta) dehydrogenase 1	steroid metabolic process	Biological process	-
APOA1	335	apolipoprotein A-I	negative regulation of interleukin-1 beta secretion	Biological process	12458630
NFKB1	4790	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	membrane protein intracellular domain proteolysis	Biological process	-
OPHN1	4983	oligophrenin 1	positive regulation of GTPase activity	Biological process	9582072
LMNA	4000	lamin A/C	ventricular cardiac muscle cell development	Biological process	-
EIF2AK3	9451	eukaryotic translation initiation factor 2-alpha kinase 3	bone mineralization	Biological process	-
RNASEH1	246243	ribonuclease H1	magnesium ion binding	Molecular function	-
PEBP4	157310	phosphatidylethanolamine-binding protein 4	protein binding	Molecular function	19197339
RORA	6095	RAR-related orphan receptor A	regulation of macrophage activation	Biological process	-
NDUFA8	4702	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa	cellular metabolic process	Biological process	-
CST4	1472	cystatin S	retina homeostasis	Biological process	23580065
G0S2	50486	G0/G1 switch 2	positive regulation of extrinsic apoptotic signaling pathway	Biological process	19706769
KIAA1143	57456	KIAA1143	protein binding	Molecular function	21516116
INHA	3623	inhibin, alpha	protein binding	Molecular function	10746731
GBA	2629	glucosidase, beta, acid	negative regulation of inflammatory response	Biological process	19279008
TRIM31	11074	tripartite motif containing 31	negative regulation of viral entry into host cell	Biological process	18248090
ITPR3	3710	inositol 1,4,5-trisphosphate receptor, type 3	inositol hexakisphosphate binding	Molecular function	-
NLRC4	58484	NLR family, CARD domain containing 4	positive regulation of apoptotic process	Biological process	12646168
GZMB	3002	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	cytoplasm	Cellular component	-
RGCC	28984	regulator of cell cycle	positive regulation of sequence-specific DNA binding transcription factor activity	Biological process	19158077
BCR	613	breakpoint cluster region	brain development	Biological process	-
RPS6KB1	6198	ribosomal protein S6 kinase, 70kDa, polypeptide 1	response to drug	Biological process	-
RERE	473	arginine-glutamic acid dipeptide (RE) repeats	nucleus	Cellular component	10814707
NUMA1	4926	nuclear mitotic apparatus protein 1	chromosome	Cellular component	-
ITGAL	3683	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	positive regulation of T cell proliferation	Biological process	-
PTPRK	5796	protein tyrosine phosphatase, receptor type, K	integral component of plasma membrane	Cellular component	9047348
PTCD3	55037	pentatricopeptide repeat domain 3	rRNA binding	Molecular function	19427859
STMN1	3925	stathmin 1	membrane	Cellular component	-
CRKL	1399	v-crk avian sarcoma virus CT10 oncogene homolog-like	endosome	Cellular component	-
LINGO1	84894	leucine rich repeat and Ig domain containing 1	neuron projection development	Biological process	-
EXOC3L1	283849	exocyst complex component 3-like 1	peptide hormone secretion	Biological process	18480549
UBE2J2	118424	ubiquitin-conjugating enzyme E2, J2	endoplasmic reticulum membrane	Cellular component	-
NOG	9241	noggin	extracellular region	Cellular component	-
TADA3	10474	transcriptional adaptor 3	chromatin organization	Biological process	-
LILRB3	11025	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	transmembrane signaling receptor activity	Molecular function	9278324
ATP5F1	515	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)	Cellular component	-
KL	9365	klotho	fibroblast growth factor receptor signaling pathway	Biological process	-
SMAD4	4089	SMAD family member 4	protein homodimerization activity	Molecular function	8774881
HMGB2	3148	high mobility group box 2	base-excision repair, DNA ligation	Biological process	9600082
PAX2	5076	paired box 2	regulation of metanephric nephron tubule epithelial cell differentiation	Biological process	-
KIF3C	3797	kinesin family member 3C	microtubule-based movement	Biological process	-
PPIF	10105	peptidylprolyl isomerase F	protein binding	Molecular function	22726440
ATXN1	6310	ataxin 1	DNA binding	Molecular function	-
DUS3L	56931	dihydrouridine synthase 3-like (S. cerevisiae)	tRNA dihydrouridine synthesis	Biological process	-
S100A14	57402	S100 calcium binding protein A14	calcium ion binding	Molecular function	16682778
KIF11	3832	kinesin family member 11	cytoplasm	Cellular component	-
NCK2	8440	NCK adaptor protein 2	cytoplasm	Cellular component	12110186
PLXNB2	23654	plexin B2	neuroblast proliferation	Biological process	-
RREB1	6239	ras responsive element binding protein 1	RNA polymerase II core promoter sequence-specific DNA binding	Molecular function	20133935
RPS25	6230	ribosomal protein S25	viral life cycle	Biological process	-
WASL	8976	Wiskott-Aldrich syndrome-like	lamellipodium	Cellular component	-
MAN1A1	4121	mannosidase, alpha, class 1A, member 1	endoplasmic reticulum	Cellular component	8223597
COL8A1	1295	collagen, type VIII, alpha 1	extracellular matrix organization	Biological process	-
ELN	2006	elastin	respiratory gaseous exchange	Biological process	9873040
PRKRA	8575	protein kinase, interferon-inducible double stranded RNA dependent activator	membrane	Cellular component	19946888
OR10X1	128367	olfactory receptor, family 10, subfamily X, member 1 (gene/pseudogene)	integral component of membrane	Cellular component	-
ABCA2	20	ATP-binding cassette, sub-family A (ABC1), member 2	response to drug	Biological process	12363033
RAB6B	51560	RAB6B, member RAS oncogene family	Rab protein signal transduction	Biological process	-
HIST1H3G	8355	histone cluster 1, H3g	protein heterodimerization activity	Molecular function	-
PTAFR	5724	platelet-activating factor receptor	G-protein coupled purinergic nucleotide receptor activity	Molecular function	-
PABPC1	26986	poly(A) binding protein, cytoplasmic 1	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Biological process	18447585
RAD18	56852	RAD18 E3 ubiquitin protein ligase	zinc ion binding	Molecular function	-
GIP	2695	gastric inhibitory polypeptide	signal transduction	Biological process	2890159
RASGRP1	10125	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	cytosol	Cellular component	-
TNFRSF10B	8795	tumor necrosis factor receptor superfamily, member 10b	response to endoplasmic reticulum stress	Biological process	15322075
PXYLP1	92370	2-phosphoxylose phosphatase 1	chondroitin sulfate proteoglycan biosynthetic process	Biological process	24425863
MEF2A	4205	myocyte enhancer factor 2A	heart development	Biological process	10458488
WIPI2	26100	WD repeat domain, phosphoinositide interacting 2	pre-autophagosomal structure membrane	Cellular component	20505359
GSN	2934	gelsolin	regulation of plasma membrane raft polarization	Biological process	23575248
HTR2B	3357	5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled	positive regulation of cell division	Biological process	-
VPS4B	9525	vacuolar protein sorting 4 homolog B (S. cerevisiae)	viral life cycle	Biological process	-
UMOD	7369	uromodulin	anchored component of membrane	Cellular component	2249987
PEX5	5830	peroxisomal biogenesis factor 5	cytosol	Cellular component	11336669
ANG	283	angiogenin, ribonuclease, RNase A family, 5	activation of phospholipase C activity	Biological process	2457905
ANG	283	angiogenin, ribonuclease, RNase A family, 5	extracellular exosome	Cellular component	23376485
RANBP10	57610	RAN binding protein 10	cytoplasmic microtubule	Cellular component	-
UBA7	7318	ubiquitin-like modifier activating enzyme 7	innate immune response	Biological process	-
NR1D2	9975	nuclear receptor subfamily 1, group D, member 2	transcription initiation from RNA polymerase II promoter	Biological process	-
TFAP2E	339488	transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)	regulation of transcription from RNA polymerase II promoter	Biological process	-
ATF2	1386	activating transcription factor 2	fat cell differentiation	Biological process	-
ANXA9	8416	annexin A9	calcium-dependent phospholipid binding	Molecular function	-
KCNA1	3736	potassium channel, voltage gated shaker related subfamily A, member 1	potassium ion transmembrane transport	Biological process	19912772
DSN1	79980	DSN1, MIS12 kinetochore complex component	cytoplasm	Cellular component	-
TLE3	7090	transducin-like enhancer of split 3	regulation of transcription, DNA-templated	Biological process	-
RAD17	5884	RAD17 homolog (S. pombe)	regulation of phosphorylation	Biological process	14657349
CASQ2	845	calsequestrin 2 (cardiac muscle)	regulation of membrane repolarization	Biological process	21063088
SCO2	9997	SCO2 cytochrome c oxidase assembly protein	cellular copper ion homeostasis	Biological process	-
RSPO1	284654	R-spondin 1	regulation of receptor internalization	Biological process	17804805
DHX36	170506	DEAH (Asp-Glu-Ala-His) box polypeptide 36	response to virus	Biological process	-
ELOVL3	83401	ELOVL fatty acid elongase 3	very long-chain fatty acid biosynthetic process	Biological process	20937905
PHACTR4	65979	phosphatase and actin regulator 4	protein phosphatase type 1 activator activity	Molecular function	-
FECH	2235	ferrochelatase	small molecule metabolic process	Biological process	-
TGFB2	7042	transforming growth factor, beta 2	axon	Cellular component	-
ACOT8	10005	acyl-CoA thioesterase 8	bile acid metabolic process	Biological process	-
PAQR9	344838	progestin and adipoQ receptor family member IX	integral component of membrane	Cellular component	-
IRF9	10379	interferon regulatory factor 9	type I interferon biosynthetic process	Biological process	-
SRSF1	6426	serine/arginine-rich splicing factor 1	mRNA splice site selection	Biological process	1830244
EGFR	1956	epidermal growth factor receptor	endoplasmic reticulum membrane	Cellular component	-
NUMA1	4926	nuclear mitotic apparatus protein 1	G2/M transition of mitotic cell cycle	Biological process	-
GIMAP5	55340	GTPase, IMAP family member 5	positive regulation of humoral immune response mediated by circulating immunoglobulin	Biological process	-
UGT2B15	7366	UDP glucuronosyltransferase 2 family, polypeptide B15	endoplasmic reticulum membrane	Cellular component	-
VEPH1	79674	ventricular zone expressed PH domain-containing 1	plasma membrane	Cellular component	-
ADCY5	111	adenylate cyclase 5	signal transduction	Biological process	-
APOA2	336	apolipoprotein A-II	regulation of protein stability	Biological process	14967812
FAN1	22909	FANCD2/FANCI-associated nuclease 1	DNA repair	Biological process	20603073
PLA2G10	8399	phospholipase A2, group X	phosphatidylinositol acyl-chain remodeling	Biological process	-
TGFBR2	7048	transforming growth factor, beta receptor II (70/80kDa)	protein binding	Molecular function	11157754
TRIM36	55521	tripartite motif containing 36	cytoskeleton	Cellular component	-
NPM1	4869	nucleophosmin (nucleolar phosphoprotein B23, numatrin)	ribosome assembly	Biological process	12080348
GPR55	9290	G protein-coupled receptor 55	negative regulation of osteoclast differentiation	Biological process	19805329
DLG1	1739	discs, large homolog 1 (Drosophila)	negative regulation of mitotic cell cycle	Biological process	10656683
TRIB3	57761	tribbles pseudokinase 3	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
NOTCH4	4855	notch 4	extracellular region	Cellular component	-
RFWD2	64326	ring finger and WD repeat domain 2, E3 ubiquitin protein ligase	cytoplasm	Cellular component	-
KCNA4	3739	potassium channel, voltage gated shaker related subfamily A, member 4	integral component of plasma membrane	Cellular component	19912772
MDFI	4188	MyoD family inhibitor	cytoplasm	Cellular component	-
CMTM6	54918	CKLF-like MARVEL transmembrane domain containing 6	integral component of membrane	Cellular component	-
CHIC2	26511	cysteine-rich hydrophobic domain 2	Golgi to plasma membrane transport	Biological process	-
ALDH8A1	64577	aldehyde dehydrogenase 8 family, member A1	aldehyde dehydrogenase (NAD) activity	Molecular function	-
HSPA1B	3304	heat shock 70kDa protein 1B	COP9 signalosome	Cellular component	18850735
TFAP2A	7020	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	RNA polymerase II distal enhancer sequence-specific DNA binding	Molecular function	-
FEZ1	9638	fasciculation and elongation protein zeta 1 (zygin I)	cytoplasm	Cellular component	-
FOXD1	2297	forkhead box D1	transcription from RNA polymerase II promoter	Biological process	-
SETDB1	9869	SET domain, bifurcated 1	nucleus	Cellular component	-
NEDD1	121441	neural precursor cell expressed, developmentally down-regulated 1	cell division	Biological process	-
CLPX	10845	caseinolytic mitochondrial matrix peptidase chaperone subunit	ATP binding	Molecular function	-
F2	2147	coagulation factor II (thrombin)	positive regulation of reactive oxygen species metabolic process	Biological process	17275676
TLK2	11011	tousled-like kinase 2	cell cycle	Biological process	-
NF2	4771	neurofibromin 2 (merlin)	positive regulation of cell differentiation	Biological process	-
ARHGAP26	23092	Rho GTPase activating protein 26	plasma membrane organization	Biological process	-
HCK	3055	HCK proto-oncogene, Src family tyrosine kinase	caveola	Cellular component	7791757
REL	5966	v-rel avian reticuloendotheliosis viral oncogene homolog	negative regulation of interferon-beta production	Biological process	22065573
STX7	8417	syntaxin 7	regulation of protein localization to plasma membrane	Biological process	18570918
OR52P1P	81248	olfactory receptor, family 52, subfamily P, member 1 pseudogene	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
RPL7A	6130	ribosomal protein L7a	nucleolus	Cellular component	16791210
NOP14	8602	NOP14 nucleolar protein	rRNA processing	Biological process	-
XYLT2	64132	xylosyltransferase II	endoplasmic reticulum membrane	Cellular component	-
DVL2	1856	dishevelled segment polarity protein 2	convergent extension involved in neural plate elongation	Biological process	-
FOXO3	2309	forkhead box O3	antral ovarian follicle growth	Biological process	-
FGL1	2267	fibrinogen-like 1	fibrinogen complex	Cellular component	8390249
SLC47A2	146802	solute carrier family 47 (multidrug and toxin extrusion), member 2	integral component of membrane	Cellular component	-
ICMT	23463	isoprenylcysteine carboxyl methyltransferase	endoplasmic reticulum	Cellular component	9614111
KCNMA1	3778	potassium channel, calcium activated large conductance subfamily M alpha, member 1	micturition	Biological process	11641143
CYP3A4	1576	cytochrome P450, family 3, subfamily A, polypeptide 4	small molecule metabolic process	Biological process	-
CLTA	1211	clathrin, light chain A	membrane	Cellular component	19946888
SERPINB3	6317	serpin peptidase inhibitor, clade B (ovalbumin), member 3	serine-type endopeptidase inhibitor activity	Molecular function	7724531
CYP11B2	1585	cytochrome P450, family 11, subfamily B, polypeptide 2	steroid metabolic process	Biological process	-
NXF5	55998	nuclear RNA export factor 5	cytoplasm	Cellular component	11566096
MYBL2	4605	v-myb avian myeloblastosis viral oncogene homolog-like 2	mitotic cell cycle	Biological process	-
OVGP1	5016	oviductal glycoprotein 1, 120kDa	extracellular region	Cellular component	-
RPS6KA5	9252	ribosomal protein S6 kinase, 90kDa, polypeptide 5	toll-like receptor 3 signaling pathway	Biological process	-
G6PC	2538	glucose-6-phosphatase, catalytic subunit	endoplasmic reticulum membrane	Cellular component	-
UBR3	130507	ubiquitin protein ligase E3 component n-recognin 3 (putative)	ubiquitin protein ligase activity	Molecular function	-
CHST11	50515	carbohydrate (chondroitin 4) sulfotransferase 11	carbohydrate biosynthetic process	Biological process	-
KDR	3791	kinase insert domain receptor	vascular endothelial growth factor-activated receptor activity	Molecular function	10022831
NDUFA4	4697	NDUFA4, mitochondrial complex associated	NADH dehydrogenase (ubiquinone) activity	Molecular function	9878551
TGFBR1	7046	transforming growth factor, beta receptor 1	embryonic cranial skeleton morphogenesis	Biological process	-
ADRB1	153	adrenoceptor beta 1	nucleus	Cellular component	-
CSPG4	1464	chondroitin sulfate proteoglycan 4	signal transducer activity	Molecular function	-
COQ6	51004	coenzyme Q6 monooxygenase	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	Molecular function	-
EGFR	1956	epidermal growth factor receptor	neurotrophin TRK receptor signaling pathway	Biological process	-
SATB1	6304	SATB homeobox 1	negative regulation of transcription from RNA polymerase II promoter	Biological process	15851481
ERVK-26	103539957	endogenous retrovirus group K, member 26	mRNA transport	Biological process	-
OR13C3	138803	olfactory receptor, family 13, subfamily C, member 3	G-protein coupled receptor activity	Molecular function	-
SLC26A9	115019	solute carrier family 26 (anion exchanger), member 9	ATPase binding	Molecular function	19289574
RTCB	51493	RNA 2',3'-cyclic phosphate and 5'-OH ligase	nuclear envelope	Cellular component	25087875
MMP14	4323	matrix metallopeptidase 14 (membrane-inserted)	astrocyte cell migration	Biological process	-
ACSL3	2181	acyl-CoA synthetase long-chain family member 3	triglyceride biosynthetic process	Biological process	-
NUP37	79023	nucleoporin 37kDa	nuclear envelope	Cellular component	-
MYH3	4621	myosin, heavy chain 3, skeletal muscle, embryonic	muscle myosin complex	Cellular component	16642020
INSR	3643	insulin receptor	positive regulation of developmental growth	Biological process	7693131
COMMD1	150684	copper metabolism (Murr1) domain containing 1	Cul2-RING ubiquitin ligase complex	Cellular component	17183367
MECP2	4204	methyl CpG binding protein 2	synapse assembly	Biological process	-
MRPS9	64965	mitochondrial ribosomal protein S9	mitochondrial translational initiation	Biological process	-
FGFR4	2264	fibroblast growth factor receptor 4	positive regulation of DNA biosynthetic process	Biological process	21653700
POLQ	10721	polymerase (DNA directed), theta	protein binding	Molecular function	25642963
ATF2	1386	activating transcription factor 2	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
CRYGC	1420	crystallin, gamma C	structural constituent of eye lens	Molecular function	12507494
HIC2	23119	hypermethylated in cancer 2	nucleoplasm	Cellular component	-
STUB1	10273	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase	negative regulation of transforming growth factor beta receptor signaling pathway	Biological process	-
FLNC	2318	filamin C, gamma	ankyrin binding	Molecular function	21223964
FGF8	2253	fibroblast growth factor 8 (androgen-induced)	extracellular region	Cellular component	-
TEKT3	64518	tektin 3	nucleus	Cellular component	21630459
CUL3	8452	cullin 3	Cul3-RING ubiquitin ligase complex	Cellular component	15983046
TIA1	7072	TIA1 cytotoxic granule-associated RNA binding protein	apoptotic process	Biological process	-
ARAP1	116985	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1	positive regulation of filopodium assembly	Biological process	11804590
CA2	760	carbonic anhydrase II	bicarbonate transport	Biological process	-
FGF9	2254	fibroblast growth factor 9	extracellular space	Cellular component	8321227
ACBD5	91452	acyl-CoA binding domain containing 5	fatty-acyl-CoA binding	Molecular function	-
BLMH	642	bleomycin hydrolase	cysteine-type peptidase activity	Molecular function	8639621
CCDC85B	11007	coiled-coil domain containing 85B	negative regulation of cell growth	Biological process	17873903
DDX3X	1654	DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked	ATP-dependent DNA helicase activity	Molecular function	21589879
KIF5A	3798	kinesin family member 5A	protein localization	Biological process	-
SOCS3	9021	suppressor of cytokine signaling 3	regulation of interferon-gamma-mediated signaling pathway	Biological process	-
NR1H3	10062	nuclear receptor subfamily 1, group H, member 3	positive regulation of transcription from RNA polymerase II promoter	Biological process	17186944
NUPR1	26471	nuclear protein, transcriptional regulator, 1	male gonad development	Biological process	-
IL15	3600	interleukin 15	extracellular space	Cellular component	-
GNAT2	2780	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2	retinal cone cell development	Biological process	-
MAOB	4129	monoamine oxidase B	response to toxic substance	Biological process	-
GPSM1	26086	G-protein signaling modulator 1	endoplasmic reticulum membrane	Cellular component	-
BCL2L11	10018	BCL2-like 11 (apoptosis facilitator)	positive regulation of intrinsic apoptotic signaling pathway	Biological process	-
NCOA1	8648	nuclear receptor coactivator 1	labyrinthine layer morphogenesis	Biological process	-
NFATC2	4773	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	protein binding	Molecular function	16873067
WNT16	51384	wingless-type MMTV integration site family, member 16	keratinocyte differentiation	Biological process	17200136
ETV6	2120	ets variant 6	sequence-specific DNA binding RNA polymerase II transcription factor activity	Molecular function	-
COL19A1	1310	collagen, type XIX, alpha 1	extracellular matrix structural constituent	Molecular function	1639419
APOD	347	apolipoprotein D	cholesterol binding	Molecular function	9278274
GOLPH3	64083	golgi phosphoprotein 3 (coat-protein)	lamellipodium assembly	Biological process	23500462
POFUT1	23509	protein O-fucosyltransferase 1	protein O-linked glycosylation	Biological process	11524432
TBK1	29110	TANK-binding kinase 1	toll-like receptor 4 signaling pathway	Biological process	-
ARNTL2	56938	aryl hydrocarbon receptor nuclear translocator-like 2	regulation of transcription from RNA polymerase II promoter	Biological process	12055078
ZNF217	7764	zinc finger protein 217	transcription regulatory region DNA binding	Molecular function	18625718
COQ2	27235	coenzyme Q2 4-hydroxybenzoate polyprenyltransferase	isoprenoid biosynthetic process	Biological process	-
MTERF1	7978	mitochondrial transcription termination factor 1	mitochondrial nucleoid	Cellular component	18063578
USP33	23032	ubiquitin specific peptidase 33	ubiquitin-dependent protein catabolic process	Biological process	11739384
NOS1AP	9722	nitric oxide synthase 1 (neuronal) adaptor protein	positive regulation of nitric-oxide synthase activity	Biological process	18337493
SLC9A3R1	9368	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1	endomembrane system	Cellular component	-
AP1S3	130340	adaptor-related protein complex 1, sigma 3 subunit	lysosomal membrane	Cellular component	-
ANGPTL4	51129	angiopoietin-like 4	extracellular space	Cellular component	10698685
NEUROD1	4760	neuronal differentiation 1	transcription coactivator activity	Molecular function	14752053
TYRO3	7301	TYRO3 protein tyrosine kinase	platelet aggregation	Biological process	-
RGS6	9628	regulator of G-protein signaling 6	signal transducer activity	Molecular function	-
VPS39	23339	vacuolar protein sorting 39 homolog (S. cerevisiae)	HOPS complex	Cellular component	19109425
ERBB2	2064	erb-b2 receptor tyrosine kinase 2	wound healing	Biological process	12646923
IFI27	3429	interferon, alpha-inducible protein 27	activation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	18330707
TBX1	6899	T-box 1	DNA binding	Molecular function	17273972
ACADM	34	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	mitochondrial matrix	Cellular component	-
DGKA	1606	diacylglycerol kinase, alpha 80kDa	diacylglycerol kinase activity	Molecular function	-
KIF13A	63971	kinesin family member 13A	ATP binding	Molecular function	-
HIST1H4I	8294	histone cluster 1, H4i	telomere maintenance	Biological process	-
C5AR1	728	complement component 5a receptor 1	chemotaxis	Biological process	10352266
SRC	6714	SRC proto-oncogene, non-receptor tyrosine kinase	response to interleukin-1	Biological process	19281832
RELA	5970	v-rel avian reticuloendotheliosis viral oncogene homolog A	negative regulation of apoptotic process	Biological process	-
PTGDS	5730	prostaglandin D2 synthase 21kDa (brain)	fatty acid binding	Molecular function	20667974
SOD1	6647	superoxide dismutase 1, soluble	sensory perception of sound	Biological process	-
HNRNPUL1	11100	heterogeneous nuclear ribonucleoprotein U-like 1	response to virus	Biological process	-
PNLIP	5406	pancreatic lipase	triglyceride lipase activity	Molecular function	-
RSPH9	221421	radial spoke head 9 homolog (Chlamydomonas)	axoneme	Cellular component	19200523
SMNDC1	10285	survival motor neuron domain containing 1	nucleoplasm	Cellular component	-
AP2B1	163	adaptor-related protein complex 2, beta 1 subunit	axon guidance	Biological process	-
DOCK10	55619	dedicator of cytokinesis 10	regulation of cell migration	Biological process	18835169
TSPO	706	translocator protein (18kDa)	extracellular exosome	Cellular component	19056867
SORL1	6653	sortilin-related receptor, L(DLR class) A repeats containing	positive regulation of ER to Golgi vesicle-mediated transport	Biological process	17855360
IL23A	51561	interleukin 23, alpha subunit p19	positive regulation of T cell mediated cytotoxicity	Biological process	-
MYO5B	4645	myosin VB	vesicle-mediated transport	Biological process	17462998
MCCC1	56922	methylcrotonoyl-CoA carboxylase 1 (alpha)	mitochondrion	Cellular component	-
NAIP	4671	NLR family, apoptosis inhibitory protein	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	11896143
DPF3	8110	D4, zinc and double PHD fingers, family 3	nBAF complex	Cellular component	-
YWHAH	7533	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta	actin binding	Molecular function	-
HEXB	3074	hexosaminidase B (beta polypeptide)	small molecule metabolic process	Biological process	-
LPIN1	23175	lipin 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
CLCNKA	1187	chloride channel, voltage-sensitive Ka	integral component of plasma membrane	Cellular component	8041726
CACNA1G	8913	calcium channel, voltage-dependent, T type, alpha 1G subunit	regulation of heart rate	Biological process	-
KRT26	353288	keratin 26, type I	structural molecule activity	Molecular function	-
SOS2	6655	son of sevenless homolog 2 (Drosophila)	axon guidance	Biological process	-
EPS8	2059	epidermal growth factor receptor pathway substrate 8	barbed-end actin filament capping	Biological process	-
MEPE	56955	matrix extracellular phosphoglycoprotein	extracellular matrix structural constituent	Molecular function	10945470
CYR61	3491	cysteine-rich, angiogenic inducer, 61	atrial septum morphogenesis	Biological process	-
CD37	951	CD37 molecule	immunological synapse	Cellular component	21930792
ANXA2	302	annexin A2	angiogenesis	Biological process	11866539
CREB3	10488	cAMP responsive element binding protein 3	protein binding	Molecular function	10629049
WNT10A	80326	wingless-type MMTV integration site family, member 10A	neural crest cell differentiation	Biological process	-
CD34	947	CD34 molecule	leukocyte migration	Biological process	-
IL18BP	10068	interleukin 18 binding protein	response to lipopolysaccharide	Biological process	-
SOCS3	9021	suppressor of cytokine signaling 3	JAK-STAT cascade involved in growth hormone signaling pathway	Biological process	-
UGT1A3	54659	UDP glucuronosyltransferase 1 family, polypeptide A3	cellular glucuronidation	Biological process	20610558
RNF13	11342	ring finger protein 13	zinc ion binding	Molecular function	-
CIB1	10519	calcium and integrin binding 1 (calmyrin)	nucleus	Cellular component	11756406
LAMA1	284217	laminin, alpha 1	morphogenesis of an epithelial sheet	Biological process	-
LRRK1	79705	leucine-rich repeat kinase 1	positive regulation of intracellular signal transduction	Biological process	-
C1orf94	84970	chromosome 1 open reading frame 94	protein binding	Molecular function	16189514
MED1	5469	mediator complex subunit 1	positive regulation of hepatocyte proliferation	Biological process	-
ZNF254	9534	zinc finger protein 254	metal ion binding	Molecular function	-
GNS	2799	glucosamine (N-acetyl)-6-sulfatase	sulfuric ester hydrolase activity	Molecular function	15962010
GNA12	2768	guanine nucleotide binding protein (G protein) alpha 12	brush border membrane	Cellular component	-
ACACB	32	acetyl-CoA carboxylase beta	positive regulation of cellular metabolic process	Biological process	-
STUB1	10273	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase	SMAD binding	Molecular function	15781469
PPP6C	5537	protein phosphatase 6, catalytic subunit	cytosol	Cellular component	16716191
NUS1	116150	nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)	sterol homeostasis	Biological process	-
PPP5C	5536	protein phosphatase 5, catalytic subunit	protein heterooligomerization	Biological process	-
CDCA8	55143	cell division cycle associated 8	mitotic cell cycle	Biological process	-
LTB	4050	lymphotoxin beta (TNF superfamily, member 3)	gene expression	Biological process	-
VAPA	9218	VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa	protein domain specific binding	Molecular function	20178991
CNKSR2	22866	connector enhancer of kinase suppressor of Ras 2	neuron projection	Cellular component	-
UTS2R	2837	urotensin 2 receptor	negative regulation of blood pressure	Biological process	-
CAMK2B	816	calcium/calmodulin-dependent protein kinase II beta	calmodulin-dependent protein kinase activity	Molecular function	-
CMPK1	51727	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic	dCDP biosynthetic process	Biological process	-
SRSF9	8683	serine/arginine-rich splicing factor 9	poly(A) RNA binding	Molecular function	22658674
AURKB	9212	aurora kinase B	protein phosphorylation	Biological process	21820309
SREBF2	6721	sterol regulatory element binding transcription factor 2	lipid metabolic process	Biological process	7903453
NCOA4	8031	nuclear receptor coactivator 4	positive regulation of transcription, DNA-templated	Biological process	15572661
MSX2	4488	msh homeobox 2	branching involved in mammary gland duct morphogenesis	Biological process	-
SARM1	23098	sterile alpha and TIR motif containing 1	synapse	Cellular component	-
EFS	10278	embryonal Fyn-associated substrate	intracellular signal transduction	Biological process	9349509
RAN	5901	RAN, member RAS oncogene family	nucleus	Cellular component	21630459
KDM1A	23028	lysine (K)-specific demethylase 1A	nucleoplasm	Cellular component	-
TCF7L2	6934	transcription factor 7-like 2 (T-cell specific, HMG-box)	positive regulation of insulin secretion	Biological process	19386626
KDM1B	221656	lysine (K)-specific demethylase 1B	histone demethylase activity (H3-dimethyl-K4 specific)	Molecular function	19727073
FANCM	57697	Fanconi anemia, complementation group M	chromatin binding	Molecular function	20347429
BAIAP2	10458	BAI1-associated protein 2	actin filament bundle assembly	Biological process	-
BBS7	55212	Bardet-Biedl syndrome 7	fat cell differentiation	Biological process	-
PLA2G4F	255189	phospholipase A2, group IVF	phosphatidylglycerol acyl-chain remodeling	Biological process	-
PRKACB	5567	protein kinase, cAMP-dependent, catalytic, beta	fibroblast growth factor receptor signaling pathway	Biological process	-
DCHS1	8642	dachsous cadherin-related 1	digestive tract development	Biological process	-
MAPK9	5601	mitogen-activated protein kinase 9	positive regulation of nitric oxide biosynthetic process	Biological process	-
ALYREF	10189	Aly/REF export factor	mRNA 3'-end processing	Biological process	-
SLC9B2	133308	solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2	ion transmembrane transport	Biological process	-
ABAT	18	4-aminobutyrate aminotransferase	neuron projection	Cellular component	-
RIPK2	8767	receptor-interacting serine-threonine kinase 2	response to interleukin-12	Biological process	-
DGKQ	1609	diacylglycerol kinase, theta 110kDa	phosphorylation	Biological process	-
NUDT3	11165	nudix (nucleoside diphosphate linked moiety X)-type motif 3	magnesium ion binding	Molecular function	19585659
ADAM30	11085	ADAM metallopeptidase domain 30	integral component of membrane	Cellular component	-
ZNF526	116115	zinc finger protein 526	regulation of transcription, DNA-templated	Biological process	-
AFP	174	alpha-fetoprotein	metal ion binding	Molecular function	-
SSTR5	6755	somatostatin receptor 5	integral component of plasma membrane	Cellular component	7908405
GATA1	2623	GATA binding protein 1 (globin transcription factor 1)	eosinophil differentiation	Biological process	8507862
OR6Q1	219952	olfactory receptor, family 6, subfamily Q, member 1 (gene/pseudogene)	plasma membrane	Cellular component	-
JMY	133746	junction mediating and regulatory protein, p53 cofactor	positive regulation of sequence-specific DNA binding transcription factor activity	Biological process	-
CNTLN	54875	centlein, centrosomal protein	phosphorelay sensor kinase activity	Molecular function	-
MRPL27	51264	mitochondrial ribosomal protein L27	protein binding	Molecular function	25416956
PDXK	8566	pyridoxal (pyridoxine, vitamin B6) kinase	pyridoxal 5'-phosphate salvage	Biological process	-
POP7	10248	processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)	nucleus	Cellular component	9630247
BASP1	10409	brain abundant, membrane attached signal protein 1	vesicle	Cellular component	19190083
RNF2	6045	ring finger protein 2	gastrulation with mouth forming second	Biological process	-
TRIP6	7205	thyroid hormone receptor interactor 6	cytoskeleton	Cellular component	-
RPS24	6229	ribosomal protein S24	structural constituent of ribosome	Molecular function	18412286
RPL8	6132	ribosomal protein L8	gene expression	Biological process	-
DNAJB2	3300	DnaJ (Hsp40) homolog, subfamily B, member 2	nucleus	Cellular component	21231916
TLR7	51284	toll-like receptor 7	positive regulation of interleukin-6 production	Biological process	-
ANKRD27	84079	ankyrin repeat domain 27 (VPS9 domain)	cytoplasmic vesicle membrane	Cellular component	-
RPS6KA3	6197	ribosomal protein S6 kinase, 90kDa, polypeptide 3	regulation of translation in response to stress	Biological process	18813292
PARG	8505	poly (ADP-ribose) glycohydrolase	mitochondrial matrix	Cellular component	-
CLEC17A	388512	C-type lectin domain family 17, member A	metal ion binding	Molecular function	-
ARL15	54622	ADP-ribosylation factor-like 15	biological_process	Biological process	-
TP53INP1	94241	tumor protein p53 inducible nuclear protein 1	positive regulation of transcription, DNA-templated	Biological process	22470510
UTRN	7402	utrophin	actin binding	Molecular function	16803572
IDI1	3422	isopentenyl-diphosphate delta isomerase 1	dimethylallyl diphosphate biosynthetic process	Biological process	-
ATOH8	84913	atonal homolog 8 (Drosophila)	nervous system development	Biological process	-
DUSP12	11266	dual specificity phosphatase 12	protein tyrosine/serine/threonine phosphatase activity	Molecular function	-
HPX	3263	hemopexin	heme metabolic process	Biological process	-
HES1	3280	hes family bHLH transcription factor 1	cell morphogenesis involved in neuron differentiation	Biological process	-
SLC22A1	6580	solute carrier family 22 (organic cation transporter), member 1	organic cation transmembrane transporter activity	Molecular function	9187257
MYBL2	4605	v-myb avian myeloblastosis viral oncogene homolog-like 2	mitotic spindle assembly	Biological process	-
DUSP1	1843	dual specificity phosphatase 1	inactivation of MAPK activity	Biological process	-
NAB2	4665	NGFI-A binding protein 2 (EGR1 binding protein 2)	transcription factor binding	Molecular function	-
SOX30	11063	SRY (sex determining region Y)-box 30	transcription from RNA polymerase II promoter	Biological process	10359848
PRKCA	5578	protein kinase C, alpha	neurotrophin TRK receptor signaling pathway	Biological process	-
RIPK3	11035	receptor-interacting serine-threonine kinase 3	plasma membrane	Cellular component	-
TNFRSF11B	4982	tumor necrosis factor receptor superfamily, member 11b	response to magnesium ion	Biological process	-
LONP1	9361	lon peptidase 1, mitochondrial	regulation of mitochondrial DNA replication	Biological process	-
OR51A7	119687	olfactory receptor, family 51, subfamily A, member 7	plasma membrane	Cellular component	-
SMNDC1	10285	survival motor neuron domain containing 1	protein binding	Molecular function	15494309
ACTG1	71	actin gamma 1	membrane	Cellular component	19946888
EEA1	8411	early endosome antigen 1	extracellular exosome	Cellular component	19056867
SLC25A16	8034	solute carrier family 25 (mitochondrial carrier), member 16	antiporter activity	Molecular function	2575220
PGAP3	93210	post-GPI attachment to proteins 3	GPI anchor metabolic process	Biological process	17021251
HDAC7	51564	histone deacetylase 7	transcription corepressor activity	Molecular function	-
ELK4	2005	ELK4, ETS-domain protein (SRF accessory protein 1)	sequence-specific DNA binding	Molecular function	-
IGFBP4	3487	insulin-like growth factor binding protein 4	regulation of insulin-like growth factor receptor signaling pathway	Biological process	-
SETD1B	23067	SET domain containing 1B	regulation of transcription, DNA-templated	Biological process	-
LECT1	11061	leukocyte cell derived chemotaxin 1	proteinaceous extracellular matrix	Cellular component	-
RIMS3	9783	regulating synaptic membrane exocytosis 3	ion channel binding	Molecular function	-
GYS2	2998	glycogen synthase 2 (liver)	glucose metabolic process	Biological process	-
SLAMF1	6504	signaling lymphocytic activation molecule family member 1	regulation of catalytic activity	Biological process	-
FDFT1	2222	farnesyl-diphosphate farnesyltransferase 1	endoplasmic reticulum	Cellular component	-
OSR2	116039	odd-skipped related transciption factor 2	palate development	Biological process	-
SPAG9	9043	sperm associated antigen 9	cytosol	Cellular component	-
CWF19L2	143884	CWF19-like 2, cell cycle control (S. pombe)	catalytic activity	Molecular function	-
MYH9	4627	myosin, heavy chain 9, non-muscle	cell-cell adherens junction	Cellular component	-
HARBI1	283254	harbinger transposase derived 1	nucleic acid phosphodiester bond hydrolysis	Biological process	-
PPP2R5B	5526	protein phosphatase 2, regulatory subunit B', beta	cytosol	Cellular component	-
CENPF	1063	centromere protein F, 350/400kDa	perinuclear region of cytoplasm	Cellular component	-
DLG5	9231	discs, large homolog 5 (Drosophila)	protein localization to adherens junction	Biological process	-
TOP2B	7155	topoisomerase (DNA) II beta 180kDa	nucleolus	Cellular component	9049244
IL26	55801	interleukin 26	extracellular space	Cellular component	18483078
ANAPC11	51529	anaphase promoting complex subunit 11	ubiquitin-protein transferase activity	Molecular function	11739784
ACCS	84680	1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)	biosynthetic process	Biological process	-
FURIN	5045	furin (paired basic amino acid cleaving enzyme)	peptide binding	Molecular function	8940009
RBBP8	5932	retinoblastoma binding protein 8	RNA polymerase II transcription corepressor activity	Molecular function	16287852
SHISA5	51246	shisa family member 5	positive regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	12761501
BMP4	652	bone morphogenetic protein 4	kidney development	Biological process	18305125
KMT2D	8085	lysine (K)-specific methyltransferase 2D	regulation of transcription, DNA-templated	Biological process	9247308
BECN1	8678	beclin 1, autophagy related	cellular response to nitrogen starvation	Biological process	-
OTX2	5015	orthodenticle homeobox 2	positive regulation of gastrulation	Biological process	-
SCG2	7857	secretogranin II	protein binding	Molecular function	25416956
ADGRG1	9289	adhesion G protein-coupled receptor G1	cell-cell signaling	Biological process	10049584
FAT1	2195	FAT atypical cadherin 1	filopodium	Cellular component	-
E2F4	1874	E2F transcription factor 4, p107/p130-binding	sequence-specific DNA binding transcription factor activity	Molecular function	11418595
ZNF770	54989	zinc finger protein 770	regulation of transcription from RNA polymerase II promoter	Biological process	-
RNF7	9616	ring finger protein 7	nucleoplasm	Cellular component	-
SEMA5A	9037	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	semaphorin receptor binding	Molecular function	-
RASSF2	9770	Ras association (RalGDS/AF-6) domain family member 2	regulation of osteoblast differentiation	Biological process	-
PRKAG2	51422	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	insulin receptor signaling pathway	Biological process	-
PPP1R1B	84152	protein phosphatase 1, regulatory (inhibitor) subunit 1B	protein binding	Molecular function	25416956
SOD2	6648	superoxide dismutase 2, mitochondrial	glutathione metabolic process	Biological process	-
CENPN	55839	centromere protein N	nucleus	Cellular component	-
C1orf95	375057	chromosome 1 open reading frame 95	integral component of membrane	Cellular component	-
STAT3	6774	signal transducer and activator of transcription 3 (acute-phase response factor)	astrocyte differentiation	Biological process	-
SAMSN1	64092	SAM domain, SH3 domain and nuclear localization signals 1	nucleus	Cellular component	11594764
BLM	641	Bloom syndrome, RecQ helicase-like	alpha-beta T cell differentiation	Biological process	-
YWHAZ	7534	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta	transcription initiation from RNA polymerase II promoter	Biological process	-
YIPF4	84272	Yip1 domain family, member 4	integral component of membrane	Cellular component	-
XRCC6	2547	X-ray repair complementing defective repair in Chinese hamster cells 6	ATP-dependent DNA helicase activity	Molecular function	-
AIP	9049	aryl hydrocarbon receptor interacting protein	transcription factor binding	Molecular function	9447995
KY	339855	kyphoscoliosis peptidase	proteolysis	Biological process	-
KCNAB2	8514	potassium channel, voltage gated subfamily A regulatory beta subunit 2	oxidation-reduction process	Biological process	-
PLA2G1B	5319	phospholipase A2, group IB (pancreas)	intracellular signal transduction	Biological process	15528384
ACVRL1	94	activin A receptor type II-like 1	neuronal cell body	Cellular component	-
MAPK8	5599	mitogen-activated protein kinase 8	intrinsic apoptotic signaling pathway	Biological process	-
GAS1	2619	growth arrest-specific 1	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	Biological process	-
SDCBP	6386	syndecan binding protein (syntenin)	adherens junction	Cellular component	11179419
PTPN22	26191	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	SH3 domain binding	Molecular function	-
DNMT3A	1788	DNA (cytosine-5-)-methyltransferase 3 alpha	DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates	Molecular function	-
SPATA6	54558	spermatogenesis associated 6	extracellular region	Cellular component	-
CPOX	1371	coproporphyrinogen oxidase	mitochondrial inner membrane	Cellular component	-
HNRNPA2B1	3181	heterogeneous nuclear ribonucleoprotein A2/B1	RNA transport	Biological process	17004321
NOS1	4842	nitric oxide synthase 1 (neuronal)	response to heat	Biological process	18048451
DYRK1A	1859	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	ATP binding	Molecular function	-
AZIN2	113451	antizyme inhibitor 2	ornithine decarboxylase activity	Molecular function	-
WNT3A	89780	wingless-type MMTV integration site family, member 3A	extracellular region	Cellular component	-
DLX3	1747	distal-less homeobox 3	odontoblast differentiation	Biological process	-
FAM213B	127281	family with sequence similarity 213, member B	cytosol	Cellular component	-
SFXN1	94081	sideroflexin 1	mitochondrion	Cellular component	-
KCNMA1	3778	potassium channel, calcium activated large conductance subfamily M alpha, member 1	response to hypoxia	Biological process	15528406
CENPU	79682	centromere protein U	small GTPase mediated signal transduction	Biological process	-
ATF4	468	activating transcription factor 4	positive regulation of vascular endothelial growth factor production	Biological process	22915762
KDM1A	23028	lysine (K)-specific demethylase 1A	positive regulation of erythrocyte differentiation	Biological process	-
SEMA6C	10500	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C	axon guidance	Biological process	-
SOS1	6654	son of sevenless homolog 1 (Drosophila)	protein binding	Molecular function	10026169
CALM3	808	calmodulin 3 (phosphorylase kinase, delta)	glucose metabolic process	Biological process	-
RNF207	388591	ring finger protein 207	perinuclear region of cytoplasm	Cellular component	25281747
OTOF	9381	otoferlin	cytosol	Cellular component	10192385
PARD3	56288	par-3 family cell polarity regulator	wound healing, spreading of cells	Biological process	-
XRN2	22803	5'-3' exoribonuclease 2	RNA phosphodiester bond hydrolysis, exonucleolytic	Biological process	10409438
SCN4B	6330	sodium channel, voltage gated, type IV beta subunit	sodium ion transport	Biological process	12930796
ALDOC	230	aldolase C, fructose-bisphosphate	epithelial cell differentiation	Biological process	21492153
SLC26A3	1811	solute carrier family 26 (anion exchanger), member 3	cellular response to cAMP	Biological process	-
ABCD4	5826	ATP-binding cassette, sub-family D (ALD), member 4	endoplasmic reticulum membrane	Cellular component	-
SLC39A1	27173	solute carrier family 39 (zinc transporter), member 1	plasma membrane	Cellular component	-
LRP6	4040	low density lipoprotein receptor-related protein 6	embryonic forelimb morphogenesis	Biological process	-
AHSG	197	alpha-2-HS-glycoprotein	regulation of bone mineralization	Biological process	3474608
OR10G2	26534	olfactory receptor, family 10, subfamily G, member 2	G-protein coupled receptor signaling pathway	Biological process	-
GTF2H4	2968	general transcription factor IIH, polypeptide 4, 52kDa	transcription initiation from RNA polymerase I promoter	Biological process	-
RAD51	5888	RAD51 recombinase	DNA recombination	Biological process	7988572
CD74	972	CD74 molecule, major histocompatibility complex, class II invariant chain	negative regulation of apoptotic process	Biological process	12782713
FLOT2	2319	flotillin 2	cortical actin cytoskeleton	Cellular component	24046456
XPC	7508	xeroderma pigmentosum, complementation group C	single-stranded DNA binding	Molecular function	12509299
ERVK-6	64006	endogenous retrovirus group K, member 6	DNA biosynthetic process	Biological process	-
CDH13	1012	cadherin 13	adherens junction organization	Biological process	-
PRKCH	5583	protein kinase C, eta	positive regulation of glial cell proliferation	Biological process	10806212
TFAP2B	7021	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	positive regulation of transcription from RNA polymerase II promoter	Biological process	12169688
CCDC151	115948	coiled-coil domain containing 151	regulation of cilium assembly	Biological process	-
BST2	684	bone marrow stromal cell antigen 2	response to virus	Biological process	19036818
ARHGAP10	79658	Rho GTPase activating protein 10	cytosol	Cellular component	-
NPHS2	7827	nephrosis 2, idiopathic, steroid-resistant (podocin)	plasma membrane	Cellular component	-
GRIN1	2902	glutamate receptor, ionotropic, N-methyl D-aspartate 1	response to fungicide	Biological process	-
SLC5A6	8884	solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6	sodium-dependent multivitamin transmembrane transporter activity	Molecular function	-
ARL8B	55207	ADP-ribosylation factor-like 8B	small GTPase mediated signal transduction	Biological process	-
RNF4	6047	ring finger protein 4	positive regulation of transcription from RNA polymerase II promoter	Biological process	12885770
BAX	581	BCL2-associated X protein	thymocyte apoptotic process	Biological process	-
COQ6	51004	coenzyme Q6 monooxygenase	oxidation-reduction process	Biological process	-
CKAP2	26586	cytoskeleton associated protein 2	spindle pole	Cellular component	-
BCL9	607	B-cell CLL/lymphoma 9	regulation of transforming growth factor beta receptor signaling pathway	Biological process	19328798
OR5D18	219438	olfactory receptor, family 5, subfamily D, member 18	G-protein coupled receptor signaling pathway	Biological process	-
ADCYAP1R1	117	adenylate cyclase activating polypeptide 1 (pituitary) receptor type I	neurotrophin TRK receptor signaling pathway	Biological process	-
IFNG	3458	interferon, gamma	sensory perception of mechanical stimulus	Biological process	-
MGMT	4255	O-6-methylguanine-DNA methyltransferase	positive regulation of DNA repair	Biological process	-
TPGS1	91978	tubulin polyglutamylase complex subunit 1	axon	Cellular component	-
NOTCH1	4851	notch 1	cardiac right ventricle formation	Biological process	-
TP53	7157	tumor protein p53	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	17146433
SYN3	8224	synapsin III	cell junction	Cellular component	-
ATRAID	51374	all-trans retinoic acid-induced differentiation factor	positive regulation of osteoblast differentiation	Biological process	21723284
CFB	629	complement factor B	innate immune response	Biological process	-
MRPL12	6182	mitochondrial ribosomal protein L12	mitochondrial translational initiation	Biological process	-
TFEB	7942	transcription factor EB	transcription regulatory region DNA binding	Molecular function	19556463
IFNA17	3451	interferon, alpha 17	regulation of type I interferon-mediated signaling pathway	Biological process	-
NMU	10874	neuromedin U	receptor binding	Molecular function	10811630
SMC1A	8243	structural maintenance of chromosomes 1A	protein binding	Molecular function	11076961
VCX3A	51481	variable charge, X-linked 3A	nucleus	Cellular component	-
PSMD13	5719	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	nucleoplasm	Cellular component	-
NOTCH3	4854	notch 3	integral component of membrane	Cellular component	-
PAX2	5076	paired box 2	superoxide-generating NADPH oxidase activity	Molecular function	-
UBXN2B	137886	UBX domain protein 2B	cytosol	Cellular component	-
NUP62	23636	nucleoporin 62kDa	nuclear membrane	Cellular component	-
IL17F	112744	interleukin 17F	regulation of interleukin-6 biosynthetic process	Biological process	11574464
HES1	3280	hes family bHLH transcription factor 1	smoothened signaling pathway	Biological process	-
FUZ	80199	fuzzy planar cell polarity protein	positive regulation of cilium assembly	Biological process	21840926
CHD8	57680	chromodomain helicase DNA binding protein 8	negative regulation of fibroblast apoptotic process	Biological process	-
PTPN11	5781	protein tyrosine phosphatase, non-receptor type 11	negative regulation of cell adhesion mediated by integrin	Biological process	-
DLX2	1746	distal-less homeobox 2	chromatin binding	Molecular function	-
XRCC4	7518	X-ray repair complementing defective repair in Chinese hamster cells 4	cytosol	Cellular component	9259561
TLR8	51311	toll-like receptor 8	toll-like receptor 9 signaling pathway	Biological process	-
ZNF16	7564	zinc finger protein 16	metal ion binding	Molecular function	-
TEX13A	56157	testis expressed 13A	zinc ion binding	Molecular function	-
PAIP1	10605	poly(A) binding protein interacting protein 1	translational initiation	Biological process	9548260
KDM5A	5927	lysine (K)-specific demethylase 5A	circadian regulation of gene expression	Biological process	-
PAX2	5076	paired box 2	oxidation-reduction process	Biological process	-
PRKCD	5580	protein kinase C, delta	nuclear matrix	Cellular component	-
MYLK	4638	myosin light chain kinase	actin filament organization	Biological process	-
HGS	9146	hepatocyte growth factor-regulated tyrosine kinase substrate	positive regulation of gene expression	Biological process	18767904
TFEC	22797	transcription factor EC	protein dimerization activity	Molecular function	-
SALL1	6299	spalt-like transcription factor 1	ureteric bud invasion	Biological process	-
AGO4	192670	argonaute RISC catalytic component 4	membrane	Cellular component	19946888
TUBA3E	112714	tubulin, alpha 3e	nucleus	Cellular component	21630459
FADD	8772	Fas (TNFRSF6)-associated via death domain	membrane raft	Cellular component	-
CAD	790	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	protein complex	Cellular component	-
IFNA10	3446	interferon, alpha 10	adaptive immune response	Biological process	-
NUDT5	11164	nudix (nucleoside diphosphate linked moiety X)-type motif 5	D-ribose catabolic process	Biological process	10567213
SIGLEC15	284266	sialic acid binding Ig-like lectin 15	regulation of actin cytoskeleton organization	Biological process	-
HOXD9	3235	homeobox D9	adult locomotory behavior	Biological process	-
STKLD1	169436	serine/threonine kinase-like domain containing 1	ATP binding	Molecular function	-
PPP1R3C	5507	protein phosphatase 1, regulatory subunit 3C	regulation of catalytic activity	Biological process	-
USP13	8975	ubiquitin specific peptidase 13 (isopeptidase T-3)	autophagy	Biological process	-
SEMA6D	80031	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	axon guidance	Biological process	-
CUZD1	50624	CUB and zona pellucida-like domains 1	zymogen granule membrane	Cellular component	-
ZFHX3	463	zinc finger homeobox 3	intracellular membrane-bounded organelle	Cellular component	-
GDNF	2668	glial cell derived neurotrophic factor	mesenchymal to epithelial transition involved in metanephros morphogenesis	Biological process	-
ZNF121	7675	zinc finger protein 121	nucleus	Cellular component	-
ECT2	1894	epithelial cell transforming 2	positive regulation of protein import into nucleus	Biological process	-
HNF1B	6928	HNF1 homeobox B	genitalia development	Biological process	16801329
TOR1A	1861	torsin family 1, member A (torsin A)	nuclear membrane organization	Biological process	-
NEURL2	140825	neuralized E3 ubiquitin protein ligase 2	protein ubiquitination	Biological process	-
IFNA8	3445	interferon, alpha 8	humoral immune response	Biological process	-
PSMD1	5707	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	cellular nitrogen compound metabolic process	Biological process	-
L1RE1	4029	LINE1 retrotransposable element 1	single-stranded DNA binding	Molecular function	19139409
P2RY13	53829	purinergic receptor P2Y, G-protein coupled, 13	plasma membrane	Cellular component	-
SALL1	6299	spalt-like transcription factor 1	cytoplasm	Cellular component	12065233
HCFC1	3054	host cell factor C1	regulation of protein complex assembly	Biological process	10675337
PHRF1	57661	PHD and ring finger domains 1	mRNA processing	Biological process	-
ARF1	375	ADP-ribosylation factor 1	COPI coating of Golgi vesicle	Biological process	-
S100B	6285	S100 calcium binding protein B	RAGE receptor binding	Molecular function	15033494
SPTAN1	6709	spectrin, alpha, non-erythrocytic 1	actin filament capping	Biological process	-
OR4X2	119764	olfactory receptor, family 4, subfamily X, member 2 (gene/pseudogene)	olfactory receptor activity	Molecular function	-
IRF7	3665	interferon regulatory factor 7	endosome membrane	Cellular component	-
PIGX	54965	phosphatidylinositol glycan anchor biosynthesis, class X	endoplasmic reticulum membrane	Cellular component	-
LIMK1	3984	LIM domain kinase 1	cytosol	Cellular component	-
ACE2	59272	angiotensin I converting enzyme 2	positive regulation of gap junction assembly	Biological process	12967627
PTPRK	5796	protein tyrosine phosphatase, receptor type, K	negative regulation of cell cycle	Biological process	15899872
ULK1	8408	unc-51 like autophagy activating kinase 1	protein localization	Biological process	16940348
CLU	1191	clusterin	cell morphogenesis	Biological process	15857407
CEACAM1	634	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	integral component of membrane	Cellular component	11994468
ULBP3	79465	UL16 binding protein 3	natural killer cell lectin-like receptor binding	Molecular function	11239445
ANGPTL3	27329	angiopoietin-like 3	acylglycerol homeostasis	Biological process	17110602
BICD1	636	bicaudal D homolog 1 (Drosophila)	RNA processing	Biological process	9367685
ZIC2	7546	Zic family member 2	metal ion binding	Molecular function	-
CHST2	9435	carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2	trans-Golgi network	Cellular component	12855678
EXOSC8	11340	exosome component 8	exoribonuclease activity	Molecular function	17174896
CDK5	1020	cyclin-dependent kinase 5	negative regulation of protein ubiquitination	Biological process	-
TYW1	55253	tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)	iron ion binding	Molecular function	-
KAT5	10524	K(lysine) acetyltransferase 5	androgen receptor signaling pathway	Biological process	15572661
COPB1	1315	coatomer protein complex, subunit beta 1	COPI vesicle coat	Cellular component	-
KLF4	9314	Kruppel-like factor 4 (gut)	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	20551324
TBC1D1	23216	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1	regulation of cilium assembly	Biological process	17646400
RETSAT	54884	retinol saturase (all-trans-retinol 13,14-reductase)	endoplasmic reticulum membrane	Cellular component	15358783
SDCBP2	27111	syndecan binding protein (syntenin) 2	protein C-terminus binding	Molecular function	11152476
KARS	3735	lysyl-tRNA synthetase	tRNA processing	Biological process	10952987
ZNF12	7559	zinc finger protein 12	transcription, DNA-templated	Biological process	-
ODF1	4956	outer dense fiber of sperm tails 1	protein binding	Molecular function	25416956
CTH	1491	cystathionine gamma-lyase	cellular nitrogen compound metabolic process	Biological process	-
FBXL7	23194	F-box and leucine-rich repeat protein 7	ubiquitin-dependent protein catabolic process	Biological process	10531035
ASPM	259266	asp (abnormal spindle) homolog, microcephaly associated (Drosophila)	oogenesis	Biological process	-
PARK7	11315	parkinson protein 7	positive regulation of protein localization to nucleus	Biological process	22492997
CTIF	9811	CBP80/20-dependent translation initiation factor	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Biological process	19648179
ZNF488	118738	zinc finger protein 488	nucleus	Cellular component	-
ZPLD1	131368	zona pellucida-like domain containing 1	integral component of membrane	Cellular component	-
MS4A1	931	membrane-spanning 4-domains, subfamily A, member 1	extracellular space	Cellular component	22664934
YIPF7	285525	Yip1 domain family, member 7	integral component of membrane	Cellular component	-
YKT6	10652	YKT6 v-SNARE homolog (S. cerevisiae)	metabolic process	Biological process	-
DNAJC1	64215	DnaJ (Hsp40) homolog, subfamily C, member 1	negative regulation of proteolysis	Biological process	14668352
HIST1H3C	8352	histone cluster 1, H3c	nuclear chromosome	Cellular component	14718166
PCDHB1	29930	protocadherin beta 1	integral component of membrane	Cellular component	-
OSBPL1A	114876	oxysterol binding protein-like 1A	nucleus	Cellular component	-
SYTL4	94121	synaptotagmin-like 4	clathrin binding	Molecular function	-
TFAP2B	7021	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	regulation of transcription, DNA-templated	Biological process	12169688
NOTCH4	4855	notch 4	protein heterodimerization activity	Molecular function	8681805
RNF168	165918	ring finger protein 168, E3 ubiquitin protein ligase	site of double-strand break	Cellular component	19500350
SOX12	6666	SRY (sex determining region Y)-box 12	DNA binding	Molecular function	9215677
CHRNA3	1136	cholinergic receptor, nicotinic, alpha 3 (neuronal)	neuronal cell body	Cellular component	-
RAPGEF5	9771	Rap guanine nucleotide exchange factor (GEF) 5	GTP-dependent protein binding	Molecular function	10934204
MAEL	84944	maelstrom spermatogenic transposon silencer	piP-body	Cellular component	-
ANGPTL4	51129	angiopoietin-like 4	protein binding	Molecular function	21397862
LINC00862	554279	long intergenic non-protein coding RNA 862	integral component of membrane	Cellular component	-
CACNG5	27091	calcium channel, voltage-dependent, gamma subunit 5	ion transmembrane transporter activity	Molecular function	10613843
MMS19	64210	MMS19 nucleotide excision repair homolog (S. cerevisiae)	receptor signaling complex scaffold activity	Molecular function	11279242
CALCA	796	calcitonin-related polypeptide alpha	adenylate cyclase-activating G-protein coupled receptor signaling pathway	Biological process	-
ROBO2	6092	roundabout, axon guidance receptor, homolog 2 (Drosophila)	axon midline choice point recognition	Biological process	-
DAG1	1605	dystroglycan 1 (dystrophin-associated glycoprotein 1)	morphogenesis of an epithelial sheet	Biological process	-
ANK3	288	ankyrin 3, node of Ranvier (ankyrin G)	positive regulation of sodium ion transmembrane transporter activity	Biological process	18180363
NELFA	7469	negative elongation factor complex member A	viral process	Biological process	-
MED17	9440	mediator complex subunit 17	vitamin D receptor binding	Molecular function	10235266
AQP1	358	aquaporin 1 (Colton blood group)	brush border	Cellular component	16133142
ARL11	115761	ADP-ribosylation factor-like 11	hematopoietic progenitor cell differentiation	Biological process	-
TUT1	64852	terminal uridylyl transferase 1, U6 snRNA-specific	metal ion binding	Molecular function	-
ZFHX3	463	zinc finger homeobox 3	regulation of transcription, DNA-templated	Biological process	1719379
HSPG2	3339	heparan sulfate proteoglycan 2	glycosaminoglycan metabolic process	Biological process	-
TAAR9	134860	trace amine associated receptor 9 (gene/pseudogene)	trace-amine receptor activity	Molecular function	-
IQGAP1	8826	IQ motif containing GTPase activating protein 1	cellular response to calcium ion	Biological process	18567582
PAFAH1B1	5048	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	neuromuscular process controlling balance	Biological process	9063735
MAPK1	5594	mitogen-activated protein kinase 1	Golgi apparatus	Cellular component	19565474
NEUROD6	63974	neuronal differentiation 6	nucleus	Cellular component	-
PDPK1	5170	3-phosphoinositide dependent protein kinase 1	small GTPase mediated signal transduction	Biological process	-
GALNT9	50614	polypeptide N-acetylgalactosaminyltransferase 9	cellular protein metabolic process	Biological process	-
NELFE	7936	negative elongation factor complex member E	protein binding	Molecular function	12612062
ARHGEF17	9828	Rho guanine nucleotide exchange factor (GEF) 17	guanyl-nucleotide exchange factor activity	Molecular function	12071859
PADI3	51702	peptidyl arginine deiminase, type III	protein-arginine deiminase activity	Molecular function	-
FCGR3A	2214	Fc fragment of IgG, low affinity IIIa, receptor (CD16a)	plasma membrane	Cellular component	-
ASS1	445	argininosuccinate synthase 1	cellular response to lipopolysaccharide	Biological process	-
TSSK6	83983	testis-specific serine kinase 6	multicellular organismal development	Biological process	-
HOXA2	3199	homeobox A2	rhombomere 3 morphogenesis	Biological process	-
SMUG1	23583	single-strand-selective monofunctional uracil-DNA glycosylase 1	depyrimidination	Biological process	-
MEF2D	4209	myocyte enhancer factor 2D	sequence-specific DNA binding transcription factor activity	Molecular function	8575763
ATPIF1	93974	ATPase inhibitory factor 1	ATPase binding	Molecular function	-
SMARCA5	8467	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	nucleoplasm	Cellular component	-
ADAMTS1	9510	ADAM metallopeptidase with thrombospondin type 1 motif, 1	integrin-mediated signaling pathway	Biological process	8995297
ILK	3611	integrin-linked kinase	positive regulation of cell migration	Biological process	-
PPIH	10465	peptidylprolyl isomerase H (cyclophilin H)	mRNA splicing, via spliceosome	Biological process	9570313
ITGA5	3678	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	cell adhesion	Biological process	2454952
GSDMB	55876	gasdermin B	cytoplasm	Cellular component	-
IFT140	9742	intraflagellar transport 140	organelle organization	Biological process	-
HFM1	164045	HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)	helicase activity	Molecular function	-
KPNA2	3838	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	viral process	Biological process	-
PHTF2	57157	putative homeodomain transcription factor 2	endoplasmic reticulum	Cellular component	-
NODAL	4838	nodal growth differentiation factor	embryonic pattern specification	Biological process	-
CGNL1	84952	cingulin-like 1	bicellular tight junction	Cellular component	-
CAV2	858	caveolin 2	nucleus	Cellular component	-
MRTO4	51154	mRNA turnover 4 homolog (S. cerevisiae)	nucleoplasm	Cellular component	-
C11orf30	56946	chromosome 11 open reading frame 30	nucleoplasm	Cellular component	-
TSPO	706	translocator protein (18kDa)	androgen binding	Molecular function	-
NFATC1	4772	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	stimulatory C-type lectin receptor signaling pathway	Biological process	-
MAP3K1	4214	mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase	JUN kinase kinase activity	Molecular function	-
IL4	3565	interleukin 4	negative regulation of chronic inflammatory response	Biological process	-
PHOSPHO2	493911	phosphatase, orphan 2	metal ion binding	Molecular function	-
FLG2	388698	filaggrin family member 2	establishment of skin barrier	Biological process	23403047
KAT6B	23522	K(lysine) acetyltransferase 6B	DNA binding	Molecular function	-
HYOU1	10525	hypoxia up-regulated 1	IRE1-mediated unfolded protein response	Biological process	-
SLC22A3	6581	solute carrier family 22 (organic cation transporter), member 3	dopamine transport	Biological process	-
CCHCR1	54535	coiled-coil alpha-helical rod protein 1	protein binding	Molecular function	25416956
SRR	63826	serine racemase	neuronal cell body	Cellular component	17880399
CPT1A	1374	carnitine palmitoyltransferase 1A (liver)	mitochondrion	Cellular component	-
RCOR1	23186	REST corepressor 1	viral process	Biological process	-
CFL2	1073	cofilin 2 (muscle)	nuclear matrix	Cellular component	-
RC3H1	149041	ring finger and CCCH-type domains 1	spleen development	Biological process	-
U2AF1L4	199746	U2 small nuclear RNA auxiliary factor 1-like 4	metal ion binding	Molecular function	-
PPFIA2	8499	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2	protein complex binding	Molecular function	-
EMC6	83460	ER membrane protein complex subunit 6	protein binding	Molecular function	23182941
SYT15	83849	synaptotagmin XV	calcium-dependent phospholipid binding	Molecular function	-
CPS1	1373	carbamoyl-phosphate synthase 1, mitochondrial	cellular response to glucagon stimulus	Biological process	-
C1orf86	199990	chromosome 1 open reading frame 86	nucleoplasm	Cellular component	-
TANC1	85461	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1	cell junction	Cellular component	-
ZNF516	9658	zinc finger protein 516	core promoter proximal region sequence-specific DNA binding	Molecular function	-
GDF9	2661	growth differentiation factor 9	BMP signaling pathway	Biological process	-
CCDC151	115948	coiled-coil domain containing 151	cell projection organization	Biological process	-
WIPI1	55062	WD repeat domain, phosphoinositide interacting 1	pre-autophagosomal structure	Cellular component	15602573
EFTUD1	79631	elongation factor Tu GTP binding domain containing 1	GTP binding	Molecular function	-
ACE	1636	angiotensin I converting enzyme	drug binding	Molecular function	1320019
BRMS1	25855	breast cancer metastasis suppressor 1	Sin3-type complex	Cellular component	-
GALK2	2585	galactokinase 2	ATP binding	Molecular function	-
PACSIN3	29763	protein kinase C and casein kinase substrate in neurons 3	protein binding	Molecular function	10531379
TF	7018	transferrin	recycling endosome	Cellular component	15880641
AATK	9625	apoptosis-associated tyrosine kinase	protein tyrosine kinase activity	Molecular function	-
NOD1	10392	nucleotide-binding oligomerization domain containing 1	defense response to bacterium	Biological process	15653568
CELF4	56853	CUGBP, Elav-like family member 4	negative regulation of excitatory postsynaptic membrane potential	Biological process	-
GRM4	2914	glutamate receptor, metabotropic 4	activation of MAPK activity	Biological process	15102938
DSC3	1825	desmocollin 3	homophilic cell adhesion via plasma membrane adhesion molecules	Biological process	-
TRAPPC8	22878	trafficking protein particle complex 8	autophagosome assembly	Biological process	-
KLF6	1316	Kruppel-like factor 6	DNA binding	Molecular function	-
IFITM3	10410	interferon induced transmembrane protein 3	lysosomal membrane	Cellular component	-
NUP133	55746	nucleoporin 133kDa	nuclear pore outer ring	Cellular component	17363900
MMP25	64386	matrix metallopeptidase 25	plasma membrane	Cellular component	-
RAB3GAP2	25782	RAB3 GTPase activating protein subunit 2 (non-catalytic)	positive regulation of endoplasmic reticulum tubular network organization	Biological process	24891604
PMP22	5376	peripheral myelin protein 22	bleb assembly	Biological process	12107182
PCM1	5108	pericentriolar material 1	G2/M transition of mitotic cell cycle	Biological process	-
RRM2B	50484	ribonucleotide reductase M2 B (TP53 inducible)	renal system process	Biological process	-
RAB1C	441400	RAB1C, member RAS oncogene family pseudogene	protein transport	Biological process	-
DHCR7	1717	7-dehydrocholesterol reductase	post-embryonic development	Biological process	-
GOLGA7	51125	golgin A7	protein binding	Molecular function	14522980
TP53I3	9540	tumor protein p53 inducible protein 3	oxidation-reduction process	Biological process	-
ARF1	375	ADP-ribosylation factor 1	long term synaptic depression	Biological process	-
C14orf166	51637	chromosome 14 open reading frame 166	RNA transport	Biological process	24608264
SPON2	10417	spondin 2, extracellular matrix protein	positive regulation of tumor necrosis factor production	Biological process	-
ABO	28	ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)	glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity	Molecular function	-
CSF1	1435	colony stimulating factor 1 (macrophage)	CSF1-CSF1R complex	Cellular component	19017797
KIF22	3835	kinesin family member 22	microtubule-based movement	Biological process	-
CEACAM1	634	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	plasma membrane	Cellular component	-
CSK	1445	c-src tyrosine kinase	protein tyrosine kinase activity	Molecular function	-
PML	5371	promyelocytic leukemia	myeloid cell differentiation	Biological process	-
CTSV	1515	cathepsin V	kininogen binding	Molecular function	-
TSGA10	80705	testis specific, 10	cellular_component	Cellular component	-
DCAF13	25879	DDB1 and CUL4 associated factor 13	Cul4-RING E3 ubiquitin ligase complex	Cellular component	16949367
RPL13A	23521	ribosomal protein L13a	negative regulation of formation of translation preinitiation complex	Biological process	17218275
LAMA1	284217	laminin, alpha 1	laminin-3 complex	Cellular component	10964500
NDE1	54820	nudE neurodevelopment protein 1	kinetochore	Cellular component	17600710
LMO4	8543	LIM domain only 4	sequence-specific DNA binding transcription factor activity	Molecular function	10209267
VIMP	55829	VCP-interacting membrane selenoprotein	low-density lipoprotein particle	Cellular component	17374524
CIR1	9541	corepressor interacting with RBPJ, 1	mRNA processing	Biological process	-
RRAGB	10325	Ras-related GTP binding B	cellular response to starvation	Biological process	-
CD36	948	CD36 molecule (thrombospondin receptor)	positive regulation of peptidyl-tyrosine phosphorylation	Biological process	-
DYNLT3	6990	dynein, light chain, Tctex-type 3	metabolic process	Biological process	-
GPR143	4935	G protein-coupled receptor 143	G-protein coupled receptor activity	Molecular function	16524428
UBR1	197131	ubiquitin protein ligase E3 component n-recognin 1	cytoplasm	Cellular component	-
PPP1R2P1	100507444	protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 1	protein phosphatase inhibitor activity	Molecular function	-
LPAR1	1902	lysophosphatidic acid receptor 1	activation of MAPK activity	Biological process	-
FGF10	2255	fibroblast growth factor 10	positive regulation of epithelial cell proliferation involved in wound healing	Biological process	19152659
NLRP6	171389	NLR family, pyrin domain containing 6	nuclear membrane	Cellular component	-
KIF3B	9371	kinesin family member 3B	microtubule motor activity	Molecular function	9865700
TLR2	7097	toll-like receptor 2	transmembrane signaling receptor activity	Molecular function	-
SPRR1B	6699	small proline-rich protein 1B	protein binding, bridging	Molecular function	10908733
RARA	5914	retinoic acid receptor, alpha	neural tube closure	Biological process	-
CCL5	6352	chemokine (C-C motif) ligand 5	cellular response to tumor necrosis factor	Biological process	9407497
PPT1	5538	palmitoyl-protein thioesterase 1	lysosomal lumen acidification	Biological process	11722572
ZC3H12A	80149	zinc finger CCCH-type containing 12A	negative regulation of NF-kappaB transcription factor activity	Biological process	18178554
ASPM	259266	asp (abnormal spindle) homolog, microcephaly associated (Drosophila)	spindle assembly involved in meiosis	Biological process	-
KAT2B	8850	K(lysine) acetyltransferase 2B	negative regulation of cyclin-dependent protein serine/threonine kinase activity	Biological process	-
PLCB3	5331	phospholipase C, beta 3 (phosphatidylinositol-specific)	signal transducer activity	Molecular function	-
PTPN18	26469	protein tyrosine phosphatase, non-receptor type 18 (brain-derived)	peptidyl-tyrosine dephosphorylation	Biological process	8950995
TES	26136	testin LIM domain protein	poly(A) RNA binding	Molecular function	22658674
AVPR1A	552	arginine vasopressin receptor 1A	V1A vasopressin receptor binding	Molecular function	-
USP17L17	100287327	ubiquitin specific peptidase 17-like family member 17	regulation of proteasomal protein catabolic process	Biological process	-
FLRT2	23768	fibronectin leucine rich transmembrane protein 2	receptor signaling protein activity	Molecular function	10644439
ZSCAN25	221785	zinc finger and SCAN domain containing 25	sequence-specific DNA binding transcription factor activity	Molecular function	-
NUMB	8650	numb homolog (Drosophila)	negative regulation of Notch signaling pathway	Biological process	-
SERPINA5	5104	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5	platelet dense tubular network	Cellular component	9556620
DNAJC2	27000	DnaJ (Hsp40) homolog, subfamily C, member 2	'de novo' cotranslational protein folding	Biological process	16002468
CCNA2	890	cyclin A2	protein binding	Molecular function	-
OPRK1	4986	opioid receptor, kappa 1	behavior	Biological process	7624359
ADH4	127	alcohol dehydrogenase 4 (class II), pi polypeptide	NADPH:quinone reductase activity	Molecular function	-
ESR1	2099	estrogen receptor 1	estrogen response element binding	Molecular function	15345745
CYP2E1	1571	cytochrome P450, family 2, subfamily E, polypeptide 1	intracellular membrane-bounded organelle	Cellular component	-
MSR1	4481	macrophage scavenger receptor 1	cytosol	Cellular component	-
RAB3GAP1	22930	RAB3 GTPase activating protein subunit 1 (catalytic)	brain development	Biological process	20512159
ATP1B1	481	ATPase, Na+/K+ transporting, beta 1 polypeptide	transmembrane transport	Biological process	-
HEBP2	23593	heme binding protein 2	mitochondrion	Cellular component	17098234
ZBTB43	23099	zinc finger and BTB domain containing 43	regulation of transcription, DNA-templated	Biological process	-
TRAPPC1	58485	trafficking protein particle complex 1	Golgi apparatus	Cellular component	-
SURF1	6834	surfeit 1	hydrogen ion transmembrane transport	Biological process	-
TNS2	23371	tensin 2	plasma membrane	Cellular component	-
WNT3A	89780	wingless-type MMTV integration site family, member 3A	negative regulation of axon extension involved in axon guidance	Biological process	-
GAS6	2621	growth arrest-specific 6	positive regulation of protein kinase B signaling	Biological process	16359517
PRL	5617	prolactin	JAK-STAT cascade involved in growth hormone signaling pathway	Biological process	-
GALNT1	2589	polypeptide N-acetylgalactosaminyltransferase 1	perinuclear region of cytoplasm	Cellular component	12506059
CXCL10	3627	chemokine (C-X-C motif) ligand 10	negative regulation of myoblast differentiation	Biological process	-
NME1	4830	NME/NM23 nucleoside diphosphate kinase 1	nucleus	Cellular component	16130169
PIK3C2G	5288	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma	adaptive immune response	Biological process	-
ATL1	51062	atlastin GTPase 1	endoplasmic reticulum membrane	Cellular component	-
SLC22A5	6584	solute carrier family 22 (organic cation/carnitine transporter), member 5	brush border membrane	Cellular component	15523054
KIR2DL1	3802	killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1	receptor activity	Molecular function	7749980
CATSPER1	117144	cation channel, sperm associated 1	plasma membrane	Cellular component	-
ITPR3	3710	inositol 1,4,5-trisphosphate receptor, type 3	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	Molecular function	-
ZNF334	55713	zinc finger protein 334	transcription, DNA-templated	Biological process	-
PSAP	5660	prosaposin	lipid transport	Biological process	1454804
CRTC1	23373	CREB regulated transcription coactivator 1	entrainment of circadian clock by photoperiod	Biological process	-
TRRAP	8295	transformation/transcription domain-associated protein	transcription, DNA-templated	Biological process	-
MZT1	440145	mitotic spindle organizing protein 1	centrosome	Cellular component	20360068
SQSTM1	8878	sequestosome 1	mitochondrion degradation	Biological process	20098416
PREX2	80243	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2	dendrite morphogenesis	Biological process	-
ANK1	286	ankyrin 1, erythrocytic	positive regulation of organelle organization	Biological process	-
FBP1	2203	fructose-1,6-bisphosphatase 1	small molecule metabolic process	Biological process	-
ZBTB7A	51341	zinc finger and BTB domain containing 7A	multicellular organismal development	Biological process	-
RBX1	9978	ring-box 1, E3 ubiquitin protein ligase	protein monoubiquitination	Biological process	22358839
RNF146	81847	ring finger protein 146	ubiquitin protein ligase activity	Molecular function	-
BCL2	596	B-cell CLL/lymphoma 2	channel activity	Molecular function	9219694
ADAM32	203102	ADAM metallopeptidase domain 32	metalloendopeptidase activity	Molecular function	-
UGT1A9	54600	UDP glucuronosyltransferase 1 family, polypeptide A9	negative regulation of transferase activity	Biological process	20610558
PCDH12	51294	protocadherin 12	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	Biological process	-
SMO	6608	smoothened, frizzled class receptor	drug binding	Molecular function	19304771
TINF2	26277	TERF1 (TRF1)-interacting nuclear factor 2	nucleoplasm	Cellular component	-
TPI1	7167	triosephosphate isomerase 1	cytosol	Cellular component	-
SQSTM1	8878	sequestosome 1	cytoplasmic mRNA processing body	Cellular component	20357094
SLC27A5	10998	solute carrier family 27 (fatty acid transporter), member 5	plasma membrane long-chain fatty acid transport	Biological process	-
TMEM101	84336	transmembrane protein 101	positive regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	12761501
SYTL2	54843	synaptotagmin-like 2	syntaxin binding	Molecular function	-
EZR	7430	ezrin	filopodium	Cellular component	12082081
SLC39A6	25800	solute carrier family 39 (zinc transporter), member 6	zinc II ion transmembrane import	Biological process	15642354
LZTR1	8216	leucine-zipper-like transcription regulator 1	anatomical structure morphogenesis	Biological process	7633402
ARL4A	10124	ADP-ribosylation factor-like 4A	GTP binding	Molecular function	10980193
TRPC6	7225	transient receptor potential cation channel, subfamily C, member 6	cation transport	Biological process	9930701
ITPR1	3708	inositol 1,4,5-trisphosphate receptor, type 1	endoplasmic reticulum calcium ion homeostasis	Biological process	-
NABP2	79035	nucleic acid binding protein 2	mitotic cell cycle checkpoint	Biological process	19683501
ADAM8	101	ADAM metallopeptidase domain 8	dense core granule membrane	Cellular component	17548643
MAP4K5	11183	mitogen-activated protein kinase kinase kinase kinase 5	activation of JUN kinase activity	Biological process	9038372
MYLK2	85366	myosin light chain kinase 2	calmodulin binding	Molecular function	-
ATF4	468	activating transcription factor 4	Lewy body core	Cellular component	23392669
NEK2	4751	NIMA-related kinase 2	regulation of attachment of spindle microtubules to kinetochore	Biological process	18297113
NDUFA9	4704	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa	small molecule metabolic process	Biological process	-
RRS1	23212	RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)	nucleolus	Cellular component	-
KTN1	3895	kinectin 1 (kinesin receptor)	microtubule-based movement	Biological process	-
ATP1A4	480	ATPase, Na+/K+ transporting, alpha 4 polypeptide	potassium ion transport	Biological process	7809153
GLI1	2735	GLI family zinc finger 1	positive regulation of transcription, DNA-templated	Biological process	11238441
HOXD10	3236	homeobox D10	hindlimb morphogenesis	Biological process	-
VEGFB	7423	vascular endothelial growth factor B	heparin binding	Molecular function	-
POU3F4	5456	POU class 3 homeobox 4	regulation of transcription from RNA polymerase II promoter	Biological process	-
CFL1	1072	cofilin 1 (non-muscle)	cytoskeleton organization	Biological process	21834987
DYNC2LI1	51626	dynein, cytoplasmic 2, light intermediate chain 1	cilium assembly	Biological process	-
CTNNA2	1496	catenin (cadherin-associated protein), alpha 2	dendrite morphogenesis	Biological process	-
HIST1H4D	8360	histone cluster 1, H4d	DNA replication-dependent nucleosome assembly	Biological process	14718166
TALDO1	6888	transaldolase 1	nucleus	Cellular component	21630459
CXCL6	6372	chemokine (C-X-C motif) ligand 6	regulation of cell proliferation	Biological process	-
MTMR3	8897	myotubularin related protein 3	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	Molecular function	11676921
TEK	7010	TEK tyrosine kinase, endothelial	protein kinase activity	Molecular function	8382358
UBA52	7311	ubiquitin A-52 residue ribosomal protein fusion product 1	carbohydrate metabolic process	Biological process	-
UBA52	7311	ubiquitin A-52 residue ribosomal protein fusion product 1	translation	Biological process	-
COL1A2	1278	collagen, type I, alpha 2	extracellular matrix	Cellular component	20551380
PRNP	5621	prion protein	tubulin binding	Molecular function	16004966
TIMELESS	8914	timeless circadian clock	cellular response to DNA damage stimulus	Biological process	-
IP6K3	117283	inositol hexakisphosphate kinase 3	inositol phosphate biosynthetic process	Biological process	11502751
IL19	29949	interleukin 19	extracellular space	Cellular component	-
HIST1H4L	8368	histone cluster 1, H4l	CENP-A containing nucleosome assembly	Biological process	-
MYOM1	8736	myomesin 1	protein homodimerization activity	Molecular function	-
RDH14	57665	retinol dehydrogenase 14 (all-trans/9-cis/11-cis)	nucleus	Cellular component	21630459
CST3	1471	cystatin C	negative regulation of endopeptidase activity	Biological process	-
TNFRSF1A	7132	tumor necrosis factor receptor superfamily, member 1A	cell surface receptor signaling pathway	Biological process	-
TFAP2A	7020	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	neural crest cell development	Biological process	-
CSF2	1437	colony stimulating factor 2 (granulocyte-macrophage)	extracellular region	Cellular component	-
EN1	2019	engrailed homeobox 1	anatomical structure morphogenesis	Biological process	8094370
HDAC5	10014	histone deacetylase 5	transcription regulatory region DNA binding	Molecular function	19351956
CLEC11A	6320	C-type lectin domain family 11, member A	extracellular region	Cellular component	9442024
CYB561A3	220002	cytochrome b561 family, member A3	protein binding	Molecular function	25416956
KRT25	147183	keratin 25, type I	molecular_function	Molecular function	-
WNK4	65266	WNK lysine deficient protein kinase 4	distal tubule morphogenesis	Biological process	23453970
THOC3	84321	THO complex 3	mRNA export from nucleus	Biological process	17190602
AVEN	57099	apoptosis, caspase activation inhibitor	membrane	Cellular component	10949025
PPARG	5468	peroxisome proliferator-activated receptor gamma	protein phosphatase binding	Molecular function	-
SFTPC	6440	surfactant protein C	response to glucocorticoid	Biological process	-
OTC	5009	ornithine carbamoyltransferase	amino acid binding	Molecular function	-
SRP72	6731	signal recognition particle 72kDa	nucleolus	Cellular component	-
THAP8	199745	THAP domain containing 8	protein binding	Molecular function	25416956
LY96	23643	lymphocyte antigen 96	cell surface receptor signaling pathway	Biological process	10359581
FARS2	10667	phenylalanyl-tRNA synthetase 2, mitochondrial	protein binding	Molecular function	25416956
PAPOLA	10914	poly(A) polymerase alpha	magnesium ion binding	Molecular function	-
TGM2	7052	transglutaminase 2	blood vessel remodeling	Biological process	-
CFTR	1080	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	enzyme binding	Molecular function	19398555
POU4F1	5457	POU class 4 homeobox 1	peripheral nervous system neuron development	Biological process	-
DHX29	54505	DEAH (Asp-Glu-Ala-His) box polypeptide 29	ATP binding	Molecular function	-
RFTN1	23180	raftlin, lipid raft linker 1	double-stranded RNA binding	Molecular function	21266579
FURIN	5045	furin (paired basic amino acid cleaving enzyme)	nerve growth factor production	Biological process	8615794
LXN	56925	latexin	detection of temperature stimulus involved in sensory perception of pain	Biological process	-
CPNE9	151835	copine family member IX	positive regulation of dendrite extension	Biological process	23999003
RIPK3	11035	receptor-interacting serine-threonine kinase 3	protein serine/threonine kinase activity	Molecular function	-
ITPR3	3710	inositol 1,4,5-trisphosphate receptor, type 3	sensory perception of umami taste	Biological process	-
PLA2G1B	5319	phospholipase A2, group IB (pancreas)	activation of MAPK activity	Biological process	15528384
MYC	4609	v-myc avian myelocytomatosis viral oncogene homolog	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
ITLN1	55600	intelectin 1 (galactofuranose binding)	anchored component of membrane	Cellular component	-
CLK1	1195	CDC-like kinase 1	nucleus	Cellular component	-
AQP1	358	aquaporin 1 (Colton blood group)	nitric oxide transmembrane transporter activity	Molecular function	16682607
ATXN3	4287	ataxin 3	ubiquitin-specific protease activity	Molecular function	-
TSPO	706	translocator protein (18kDa)	negative regulation of glial cell proliferation	Biological process	-
MC3R	4159	melanocortin 3 receptor	positive regulation of cAMP biosynthetic process	Biological process	19329486
FAT3	120114	FAT atypical cadherin 3	homophilic cell adhesion via plasma membrane adhesion molecules	Biological process	-
DEFB133	403339	defensin, beta 133	extracellular region	Cellular component	-
ADCY9	115	adenylate cyclase 9	cAMP biosynthetic process	Biological process	-
ZFHX3	463	zinc finger homeobox 3	positive regulation of myoblast differentiation	Biological process	11312261
NUP85	79902	nucleoporin 85kDa	protein sumoylation	Biological process	-
RABEP1	9135	rabaptin, RAB GTPase binding effector protein 1	endocytic vesicle	Cellular component	20682791
RNF151	146310	ring finger protein 151	protein ubiquitination	Biological process	-
ATRX	546	alpha thalassemia/mental retardation syndrome X-linked	nucleosome assembly	Biological process	20651253
TFAP2B	7021	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	protein homodimerization activity	Molecular function	11505339
EZR	7430	ezrin	positive regulation of cellular protein catabolic process	Biological process	21148287
APOC2	344	apolipoprotein C-II	positive regulation of phospholipid catabolic process	Biological process	10727238
ZNF581	51545	zinc finger protein 581	nucleus	Cellular component	-
NMI	9111	N-myc (and STAT) interactor	JAK-STAT cascade	Biological process	10597290
NDST1	3340	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	MAPK cascade	Biological process	-
UBXN11	91544	UBX domain protein 11	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological process	-
PDGFA	5154	platelet-derived growth factor alpha polypeptide	protein binding	Molecular function	25241761
NDEL1	81565	nudE neurodevelopment protein 1-like 1	axon hillock	Cellular component	-
ARHGAP11A	9824	Rho GTPase activating protein 11A	GTPase activator activity	Molecular function	-
ABCA1	19	ATP-binding cassette, sub-family A (ABC1), member 1	integral component of plasma membrane	Cellular component	10525055
SLC20A1	6574	solute carrier family 20 (phosphate transporter), member 1	sodium:phosphate symporter activity	Molecular function	8041748
SKP1	6500	S-phase kinase-associated protein 1	mitotic cell cycle	Biological process	-
GLRX3	10539	glutaredoxin 3	cell redox homeostasis	Biological process	-
MTHFD2L	441024	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like	one-carbon metabolic process	Biological process	-
GJA3	2700	gap junction protein, alpha 3, 46kDa	connexon complex	Cellular component	-
RIPK3	11035	receptor-interacting serine-threonine kinase 3	regulation of adaptive immune response	Biological process	-
B4GALT1	2683	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	multicellular organism reproduction	Biological process	-
SMAD7	4092	SMAD family member 7	adherens junction assembly	Biological process	18593713
SLC9A3R1	9368	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1	cell periphery	Cellular component	17895247
ANXA1	301	annexin A1	cytoplasm	Cellular component	16130169
CUL7	9820	cullin 7	Golgi organization	Biological process	-
CXCL11	6373	chemokine (C-X-C motif) ligand 11	response to lipopolysaccharide	Biological process	-
ZFP36	7538	ZFP36 ring finger protein	cytosol	Cellular component	-
RAB8A	4218	RAB8A, member RAS oncogene family	GTP binding	Molecular function	20937701
NRARP	441478	NOTCH-regulated ankyrin repeat protein	somite rostral/caudal axis specification	Biological process	-
PVRL2	5819	poliovirus receptor-related 2 (herpesvirus entry mediator B)	adherens junction organization	Biological process	-
TCF12	6938	transcription factor 12	positive regulation of transcription from RNA polymerase II promoter	Biological process	11802795
S100A5	6276	S100 calcium binding protein A5	protein homodimerization activity	Molecular function	19536568
SORCS3	22986	sortilin-related VPS10 domain containing receptor 3	memory	Biological process	-
OPHN1	4983	oligophrenin 1	regulation of small GTPase mediated signal transduction	Biological process	-
RAD9A	5883	RAD9 homolog A (S. pombe)	exodeoxyribonuclease III activity	Molecular function	-
PRKAA2	5563	protein kinase, AMP-activated, alpha 2 catalytic subunit	metal ion binding	Molecular function	-
RELN	5649	reelin	long-term memory	Biological process	-
RNF17	56163	ring finger protein 17	cytoplasm	Cellular component	-
APOA1	335	apolipoprotein A-I	phosphatidylcholine binding	Molecular function	-
SMARCD2	6603	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2	transcription, DNA-templated	Biological process	-
LRP5	4041	low density lipoprotein receptor-related protein 5	somatic stem cell maintenance	Biological process	-
CHMP3	51652	charged multivesicular body protein 3	protein transport	Biological process	-
PRAMEF10	343071	PRAME family member 10	negative regulation of retinoic acid receptor signaling pathway	Biological process	-
CDKN1B	1027	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	autophagic cell death	Biological process	12698196
APOA1	335	apolipoprotein A-I	blood microparticle	Cellular component	22516433
TARDBP	23435	TAR DNA binding protein	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
PRPS2	5634	phosphoribosyl pyrophosphate synthetase 2	carbohydrate binding	Molecular function	-
BMP4	652	bone morphogenetic protein 4	positive regulation of transcription from RNA polymerase II promoter	Biological process	15516325
RAC2	5880	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	positive regulation of neutrophil chemotaxis	Biological process	19625648
ZNF236	7776	zinc finger protein 236	regulation of transcription, DNA-templated	Biological process	-
TLR10	81793	toll-like receptor 10	innate immune response	Biological process	-
PAK2	5062	p21 protein (Cdc42/Rac)-activated kinase 2	programmed cell death	Biological process	-
MKRN1	23608	makorin ring finger protein 1	zinc ion binding	Molecular function	-
ACP6	51205	acid phosphatase 6, lysophosphatidic	lysophosphatidic acid phosphatase activity	Molecular function	10506173
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	embryonic axis specification	Biological process	-
DPF2	5977	D4, zinc and double PHD fingers family 2	nuclear chromatin	Cellular component	16217013
GPAM	57678	glycerol-3-phosphate acyltransferase, mitochondrial	triglyceride biosynthetic process	Biological process	-
SHROOM4	57477	shroom family member 4	brain development	Biological process	16249884
CCT6B	10693	chaperonin containing TCP1, subunit 6B (zeta 2)	toxin transport	Biological process	-
GSTZ1	2954	glutathione S-transferase zeta 1	glutathione derivative biosynthetic process	Biological process	-
NFE2L2	4780	nuclear factor, erythroid 2-like 2	transcription regulatory region DNA binding	Molecular function	17015834
MICALCL	84953	MICAL C-terminal like	cell differentiation	Biological process	-
COX5A	9377	cytochrome c oxidase subunit Va	protein binding	Molecular function	25416956
TMC8	147138	transmembrane channel-like 8	ion transport	Biological process	-
YEATS4	8089	YEATS domain containing 4	histone H2A acetylation	Biological process	14966270
MC1R	4157	melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)	intracellular	Cellular component	18292087
ESR1	2099	estrogen receptor 1	nucleus	Cellular component	15569929
ERCC6	2074	excision repair cross-complementation group 6	response to X-ray	Biological process	-
IL21	59067	interleukin 21	positive regulation of natural killer cell mediated cytotoxicity	Biological process	18005035
FPR2	2358	formyl peptide receptor 2	G-protein coupled receptor signaling pathway	Biological process	-
SOD2	6648	superoxide dismutase 2, mitochondrial	superoxide metabolic process	Biological process	12551919
SLC17A6	57084	solute carrier family 17 (vesicular glutamate transporter), member 6	L-glutamate transmembrane transporter activity	Molecular function	-
ARID1A	8289	AT rich interactive domain 1A (SWI-like)	optic cup formation involved in camera-type eye development	Biological process	-
MIF	4282	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	nucleoplasm	Cellular component	-
ITGA2	3673	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	metal ion binding	Molecular function	-
CLN5	1203	ceroid-lipofuscinosis, neuronal 5	neurogenesis	Biological process	10992246
NR4A2	4929	nuclear receptor subfamily 4, group A, member 2	post-embryonic development	Biological process	-
HMGA1	3159	high mobility group AT-hook 1	regulation of transcription, DNA-templated	Biological process	10871404
MAPK14	1432	mitogen-activated protein kinase 14	cellular response to ionizing radiation	Biological process	20160708
TGFB2	7042	transforming growth factor, beta 2	positive regulation of phosphatidylinositol 3-kinase signaling	Biological process	18223299
RPTOR	57521	regulatory associated protein of MTOR, complex 1	cellular response to heat	Biological process	-
SLC26A11	284129	solute carrier family 26 (anion exchanger), member 11	anion transmembrane transport	Biological process	12626430
POM121C	100101267	POM121 transmembrane nucleoporin C	mRNA transport	Biological process	-
MTMR4	9110	myotubularin related protein 4	response to denervation involved in regulation of muscle adaptation	Biological process	-
ACVR2B	93	activin A receptor, type IIB	skeletal system morphogenesis	Biological process	-
MED31	51003	mediator complex subunit 31	protein binding	Molecular function	15383276
TMEM114	283953	transmembrane protein 114	apicolateral plasma membrane	Cellular component	-
USP17L15	100288520	ubiquitin specific peptidase 17-like family member 15	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological process	-
OR10V1	390201	olfactory receptor, family 10, subfamily V, member 1	olfactory receptor activity	Molecular function	-
RRAGC	64121	Ras-related GTP binding C	protein heterodimerization activity	Molecular function	11073942
DIS3	22894	DIS3 exosome endoribonuclease and 3'-5' exoribonuclease	nuclear exosome (RNase complex)	Cellular component	20531386
CUBN	8029	cubilin (intrinsic factor-cobalamin receptor)	steroid metabolic process	Biological process	-
PNP	4860	purine nucleoside phosphorylase	extracellular exosome	Cellular component	19056867
HLA-A	3105	major histocompatibility complex, class I, A	receptor binding	Molecular function	19124746
ARHGAP9	64333	Rho GTPase activating protein 9	small GTPase mediated signal transduction	Biological process	-
FABP3	2170	fatty acid binding protein 3, muscle and heart	phospholipid homeostasis	Biological process	-
PVR	5817	poliovirus receptor	cell adhesion	Biological process	-
HOXA3	3200	homeobox A3	regulation of transcription, DNA-templated	Biological process	-
SRC	6714	SRC proto-oncogene, non-receptor tyrosine kinase	mitochondrial inner membrane	Cellular component	12615910
ACVRL1	94	activin A receptor type II-like 1	lymphatic endothelial cell differentiation	Biological process	19903896
ITGAV	3685	integrin, alpha V	lamellipodium membrane	Cellular component	25063885
C15orf27	123591	chromosome 15 open reading frame 27	membrane depolarization during action potential	Biological process	-
NME4	4833	NME/NM23 nucleoside diphosphate kinase 4	ATP binding	Molecular function	-
PCGF5	84333	polycomb group ring finger 5	nucleolus	Cellular component	-
EPM2A	7957	epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)	polysome	Cellular component	11001928
CHIC1	53344	cysteine-rich hydrophobic domain 1	intracellular	Cellular component	-
GNAQ	2776	guanine nucleotide binding protein (G protein), q polypeptide	plasma membrane	Cellular component	-
RPL17	6139	ribosomal protein L17	poly(A) RNA binding	Molecular function	22658674
NRXN3	9369	neurexin 3	integral component of plasma membrane	Cellular component	1621094
TMPRSS11F	389208	transmembrane protease, serine 11F	integral component of plasma membrane	Cellular component	-
SEMA4F	10505	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F	axon guidance	Biological process	10051670
HIST1H3J	8356	histone cluster 1, H3j	nuclear nucleosome	Cellular component	20498094
MCTP1	79772	multiple C2 domains, transmembrane 1	calcium-mediated signaling	Biological process	15528213
RAPGEF2	9693	Rap guanine nucleotide exchange factor (GEF) 2	membrane	Cellular component	10608883
AP2B1	163	adaptor-related protein complex 2, beta 1 subunit	plasma membrane	Cellular component	-
THOC2	57187	THO complex 2	mRNA processing	Biological process	-
HINT3	135114	histidine triad nucleotide binding protein 3	cytoplasm	Cellular component	-
SPARC	6678	secreted protein, acidic, cysteine-rich (osteonectin)	platelet alpha granule	Cellular component	1737102
CAPZA2	830	capping protein (actin filament) muscle Z-line, alpha 2	cytosol	Cellular component	-
B2M	567	beta-2-microglobulin	antigen processing and presentation of peptide antigen via MHC class I	Biological process	-
HIPK2	28996	homeodomain interacting protein kinase 2	eye development	Biological process	20579985
OXCT2	64064	3-oxoacid CoA transferase 2	motile cilium	Cellular component	11756565
E2F4	1874	E2F transcription factor 4, p107/p130-binding	regulation of cell size	Biological process	-
CRY1	1407	cryptochrome circadian clock 1	nucleotide binding	Molecular function	-
PSEN2	5664	presenilin 2	cell fate specification	Biological process	-
TDG	6996	thymine-DNA glycosylase	negative regulation of protein binding	Biological process	-
RGS14	10636	regulator of G-protein signaling 14	spindle pole	Cellular component	-
SIRT1	23411	sirtuin 1	transcription factor binding	Molecular function	20955178
MED25	81857	mediator complex subunit 25	gene expression	Biological process	-
POLR3B	55703	polymerase (RNA) III (DNA directed) polypeptide B	DNA binding	Molecular function	-
PI4K2A	55361	phosphatidylinositol 4-kinase type 2 alpha	integral component of plasma membrane	Cellular component	11279162
ZNF644	84146	zinc finger protein 644	regulation of transcription, DNA-templated	Biological process	-
NUP160	23279	nucleoporin 160kDa	post-translational protein modification	Biological process	-
CDK5RAP1	51654	CDK5 regulatory subunit associated protein 1	regulation of neuron differentiation	Biological process	10721722
RPN2	6185	ribophorin II	cellular protein modification process	Biological process	10660554
EEA1	8411	early endosome antigen 1	zinc ion binding	Molecular function	11741531
SLC9A1	6548	solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1	regulation of sensory perception of pain	Biological process	-
LEF1	51176	lymphoid enhancer-binding factor 1	paraxial mesoderm formation	Biological process	-
MYO1G	64005	myosin IG	calmodulin binding	Molecular function	-
BECN1	8678	beclin 1, autophagy related	positive regulation of mitochondrion degradation	Biological process	25215947
NIPAL3	57185	NIPA-like domain containing 3	integral component of membrane	Cellular component	-
GRIN2A	2903	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	directional locomotion	Biological process	-
CHAF1A	10036	chromatin assembly factor 1, subunit A (p150)	protein complex	Cellular component	14718166
KIF11	3832	kinesin family member 11	spindle organization	Biological process	14718566
FOXG1	2290	forkhead box G1	negative regulation of transcription, DNA-templated	Biological process	12657635
SLC38A9	153129	solute carrier family 38, member 9	lysosomal membrane	Cellular component	-
A2M	2	alpha-2-macroglobulin	negative regulation of complement activation, lectin pathway	Biological process	12538697
GBX2	2637	gastrulation brain homeobox 2	thalamus development	Biological process	-
GPAT2	150763	glycerol-3-phosphate acyltransferase 2, mitochondrial	mitochondrion	Cellular component	18658143
WT1	7490	Wilms tumor 1	heart development	Biological process	10101119
BCAR1	9564	breast cancer anti-estrogen resistance 1	insulin receptor signaling pathway	Biological process	-
CAPS	828	calcyphosine	nucleus	Cellular component	-
MOBP	4336	myelin-associated oligodendrocyte basic protein	perinuclear region of cytoplasm	Cellular component	-
UBP1	7342	upstream binding protein 1 (LBP-1a)	viral genome replication	Biological process	8114710
RNF141	50862	ring finger protein 141	regulation of transcription, DNA-templated	Biological process	-
SIRT2	22933	sirtuin 2	centriole	Cellular component	17726514
DLG4	1742	discs, large homolog 4 (Drosophila)	dendritic spine morphogenesis	Biological process	-
PELP1	27043	proline, glutamate and leucine rich protein 1	membrane	Cellular component	19946888
OR10A3	26496	olfactory receptor, family 10, subfamily A, member 3	integral component of membrane	Cellular component	-
CRLS1	54675	cardiolipin synthase 1	integral component of membrane	Cellular component	-
ENO4	387712	enolase family member 4	biological_process	Biological process	-
INSIG2	51141	insulin induced gene 2	small molecule metabolic process	Biological process	-
KCNC2	3747	potassium channel, voltage gated Shaw related subfamily C, member 2	small molecule metabolic process	Biological process	-
GDF2	2658	growth differentiation factor 2	ossification	Biological process	20406889
WLS	79971	wntless Wnt ligand secretion mediator	integral component of membrane	Cellular component	-
ACTR1A	10121	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)	cytoplasm	Cellular component	-
SDCCAG8	10806	serologically defined colon cancer antigen 8	cytosol	Cellular component	-
NPLOC4	55666	nuclear protein localization 4 homolog (S. cerevisiae)	DNA repair	Biological process	-
POLR2J	5439	polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa	DNA binding	Molecular function	-
RBPJ	3516	recombination signal binding protein for immunoglobulin kappa J region	gene expression	Biological process	-
VCP	7415	valosin containing protein	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Biological process	9452483
LRP6	4040	low density lipoprotein receptor-related protein 6	thalamus development	Biological process	-
RPAIN	84268	RPA interacting protein	metal ion binding	Molecular function	-
OR56A1	120796	olfactory receptor, family 56, subfamily A, member 1	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
BEND6	221336	BEN domain containing 6	positive regulation of neuron differentiation	Biological process	-
DCK	1633	deoxycytidine kinase	protein homodimerization activity	Molecular function	12808445
SPOCK3	50859	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3	proteinaceous extracellular matrix	Cellular component	-
HCN1	348980	hyperpolarization activated cyclic nucleotide gated potassium channel 1	retinal cone cell development	Biological process	-
PRADC1	84279	protease-associated domain containing 1	protein binding	Molecular function	25416956
MECP2	4204	methyl CpG binding protein 2	poly(A) RNA binding	Molecular function	22658674
RALA	5898	v-ral simian leukemia viral oncogene homolog A (ras related)	plasma membrane	Cellular component	17875936
FADS1	3992	fatty acid desaturase 1	intracellular membrane-bounded organelle	Cellular component	10601301
PPIP5K1	9677	diphosphoinositol pentakisphosphate kinase 1	inositol-1,3,4,5,6-pentakisphosphate kinase activity	Molecular function	17412958
TTC32	130502	tetratricopeptide repeat domain 32	identical protein binding	Molecular function	-
ACTN4	81	actinin, alpha 4	protein homodimerization activity	Molecular function	15841212
PPP1CB	5500	protein phosphatase 1, catalytic subunit, beta isozyme	myosin phosphatase activity	Molecular function	-
MAPK1	5594	mitogen-activated protein kinase 1	toll-like receptor 9 signaling pathway	Biological process	-
CETP	1071	cholesteryl ester transfer protein, plasma	cholesterol homeostasis	Biological process	2586614
PRKCZ	5590	protein kinase C, zeta	activation of phospholipase D activity	Biological process	-
ABCC4	10257	ATP-binding cassette, sub-family C (CFTR/MRP), member 4	15-hydroxyprostaglandin dehydrogenase (NAD+) activity	Molecular function	7557451
CNGB1	1258	cyclic nucleotide gated channel beta 1	organelle organization	Biological process	-
HIRIP3	8479	HIRA interacting protein 3	protein binding	Molecular function	9710638
ANAPC4	29945	anaphase promoting complex subunit 4	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	Biological process	-
CYP17A1	1586	cytochrome P450, family 17, subfamily A, polypeptide 1	response to ionizing radiation	Biological process	-
UBN1	29855	ubinuclein 1	protein binding	Molecular function	18823282
TLR4	7099	toll-like receptor 4	external side of plasma membrane	Cellular component	16514062
LSM14A	26065	LSM14A, SCD6 homolog A (S. cerevisiae)	cytoplasmic stress granule	Cellular component	16484376
PPARG	5468	peroxisome proliferator-activated receptor gamma	negative regulation of telomerase activity	Biological process	-
ASB2	51676	ankyrin repeat and SOCS box containing 2	skeletal muscle cell differentiation	Biological process	-
COL19A1	1310	collagen, type XIX, alpha 1	endoplasmic reticulum lumen	Cellular component	-
NPPA	4878	natriuretic peptide A	receptor guanylyl cyclase signaling pathway	Biological process	1672777
PDE1A	5136	phosphodiesterase 1A, calmodulin-dependent	blood coagulation	Biological process	-
ZCCHC11	23318	zinc finger, CCHC domain containing 11	cytokine production	Biological process	-
SIX4	51804	SIX homeobox 4	myoblast migration	Biological process	-
FGFR1	2260	fibroblast growth factor receptor 1	phosphatidylinositol-mediated signaling	Biological process	12141425
AHNAK	79026	AHNAK nucleoprotein	nucleus	Cellular component	1608957
CD3E	916	CD3e molecule, epsilon (CD3-TCR complex)	plasma membrane	Cellular component	-
RPL29	6159	ribosomal protein L29	poly(A) RNA binding	Molecular function	22658674
PRSS12	8492	protease, serine, 12 (neurotrypsin, motopsin)	scavenger receptor activity	Molecular function	-
GNB1L	54584	guanine nucleotide binding protein (G protein), beta polypeptide 1-like	G-protein coupled receptor signaling pathway	Biological process	11072084
F2RL3	9002	coagulation factor II (thrombin) receptor-like 3	plasma membrane	Cellular component	-
KISS1R	84634	KISS1 receptor	arachidonic acid secretion	Biological process	-
COL27A1	85301	collagen, type XXVII, alpha 1	metal ion binding	Molecular function	-
CD40	958	CD40 molecule, TNF receptor superfamily member 5	cellular response to mechanical stimulus	Biological process	19593445
FRS2	10818	fibroblast growth factor receptor substrate 2	neurotrophin TRKA receptor binding	Molecular function	15488758
SLITRK5	26050	SLIT and NTRK-like family, member 5	adult behavior	Biological process	-
KANSL1	284058	KAT8 regulatory NSL complex subunit 1	nucleus	Cellular component	-
JAK1	3716	Janus kinase 1	ATP binding	Molecular function	-
EDEM1	9695	ER degradation enhancer, mannosidase alpha-like 1	protein binding	Molecular function	16449189
BMP7	655	bone morphogenetic protein 7	positive regulation of apoptotic process	Biological process	-
SPN	6693	sialophorin	signal transduction	Biological process	2023632
TMEM104	54868	transmembrane protein 104	integral component of membrane	Cellular component	-
MCM6	4175	minichromosome maintenance complex component 6	G1/S transition of mitotic cell cycle	Biological process	-
STX4	6810	syntaxin 4	positive regulation of insulin secretion involved in cellular response to glucose stimulus	Biological process	12855681
DRD2	1813	dopamine receptor D2	regulation of long-term neuronal synaptic plasticity	Biological process	-
AGO4	192670	argonaute RISC catalytic component 4	mRNA cleavage involved in gene silencing by miRNA	Biological process	15260970
HENMT1	113802	HEN1 methyltransferase homolog 1 (Arabidopsis)	protein binding	Molecular function	22458338
LRRC3	81543	leucine rich repeat containing 3	protein binding	Molecular function	17474147
GLRX3	10539	glutaredoxin 3	iron-sulfur cluster binding	Molecular function	-
E2F8	79733	E2F transcription factor 8	protein homodimerization activity	Molecular function	-
CYP2B6	1555	cytochrome P450, family 2, subfamily B, polypeptide 6	oxygen binding	Molecular function	-
HDAC8	55869	histone deacetylase 8	histone H3-K9 deacetylation	Biological process	-
GMEB1	10691	glucocorticoid modulatory element binding protein 1	regulation of transcription, DNA-templated	Biological process	-
PSMD2	5708	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	viral process	Biological process	-
DBI	1622	diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)	long-term synaptic potentiation	Biological process	-
KHDRBS1	10657	KH domain containing, RNA binding, signal transduction associated 1	protein binding	Molecular function	10913193
MPC1	51660	mitochondrial pyruvate carrier 1	mitochondrial pyruvate transport	Biological process	-
ZDHHC5	25921	zinc finger, DHHC-type containing 5	dendrite	Cellular component	-
PER2	8864	period circadian clock 2	negative regulation of DNA-templated transcription, termination	Biological process	-
FANCI	55215	Fanconi anemia, complementation group I	DNA binding	Molecular function	-
RAC1	5879	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	regulation of defense response to virus by virus	Biological process	-
CD8A	925	CD8a molecule	external side of plasma membrane	Cellular component	17213291
ATP6V1B2	526	ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2	ATP metabolic process	Biological process	-
CCT6B	10693	chaperonin containing TCP1, subunit 6B (zeta 2)	protein transport	Biological process	8812458
CADPS	8618	Ca++-dependent secretion activator	exocytosis	Biological process	1516133
FOXN2	3344	forkhead box N2	skeletal muscle cell differentiation	Biological process	-
IL37	27178	interleukin 37	extracellular space	Cellular component	-
DNAJB1	3337	DnaJ (Hsp40) homolog, subfamily B, member 1	unfolded protein binding	Molecular function	21231916
TSPAN33	340348	tetraspanin 33	plasma membrane	Cellular component	23091066
TEC	7006	tec protein tyrosine kinase	peptidyl-tyrosine autophosphorylation	Biological process	10518561
ADAP1	11033	ArfGAP with dual PH domains 1	protein binding	Molecular function	12893243
VPS45	11311	vacuolar protein sorting 45 homolog (S. cerevisiae)	protein binding	Molecular function	25416956
TNF	7124	tumor necrosis factor	leukocyte tethering or rolling	Biological process	10820279
NPFF	8620	neuropeptide FF-amide peptide precursor	positive regulation of blood pressure	Biological process	-
MED1	5469	mediator complex subunit 1	thyroid hormone receptor binding	Molecular function	9653119
IRAK1BP1	134728	interleukin-1 receptor-associated kinase 1 binding protein 1	protein binding	Molecular function	25416956
GSTZ1	2954	glutathione S-transferase zeta 1	small molecule metabolic process	Biological process	-
AURKA	6790	aurora kinase A	regulation of centrosome cycle	Biological process	19774610
PARK7	11315	parkinson protein 7	identical protein binding	Molecular function	15983381
VPS11	55823	vacuolar protein sorting 11 homolog (S. cerevisiae)	endocytic vesicle	Cellular component	20682791
PDE4D	5144	phosphodiesterase 4D, cAMP-specific	membrane	Cellular component	9371713
PVRL1	5818	poliovirus receptor-related 1 (herpesvirus entry mediator C)	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	Biological process	-
ATF4	468	activating transcription factor 4	ATF4-CREB1 transcription factor complex	Cellular component	12871976
ABCA5	23461	ATP-binding cassette, sub-family A (ABC1), member 5	lysosome	Cellular component	15870284
SLC12A2	6558	solute carrier family 12 (sodium/potassium/chloride transporter), member 2	transmembrane transport	Biological process	-
ABCB11	8647	ATP-binding cassette, sub-family B (MDR/TAP), member 11	bile acid metabolic process	Biological process	-
CYP11A1	1583	cytochrome P450, family 11, subfamily A, polypeptide 1	cholesterol metabolic process	Biological process	-
DDX51	317781	DEAD (Asp-Glu-Ala-Asp) box polypeptide 51	rRNA processing	Biological process	-
C11orf65	160140	chromosome 11 open reading frame 65	protein binding	Molecular function	25416956
CLASP2	23122	cytoplasmic linker associated protein 2	plasma membrane	Cellular component	20937854
ABL2	27	ABL proto-oncogene 2, non-receptor tyrosine kinase	protein kinase activity	Molecular function	2198571
RBM14	10432	RNA binding motif protein 14	mediator complex	Cellular component	11443112
RAB5A	5868	RAB5A, member RAS oncogene family	blood coagulation	Biological process	-
TJP2	9414	tight junction protein 2	establishment of endothelial intestinal barrier	Biological process	23885123
KCNK17	89822	potassium channel, two pore domain subfamily K, member 17	potassium ion transport	Biological process	11248242
RAB22A	57403	RAB22A, member RAS oncogene family	extracellular exosome	Cellular component	19056867
FMR1NB	158521	fragile X mental retardation 1 neighbor	integral component of membrane	Cellular component	-
PROC	5624	protein C (inactivator of coagulation factors Va and VIIIa)	negative regulation of blood coagulation	Biological process	15005336
NTSR1	4923	neurotensin receptor 1 (high affinity)	membrane raft	Cellular component	21725197
STXBP1	6812	syntaxin binding protein 1	synaptic vesicle maturation	Biological process	-
GPER1	2852	G protein-coupled estrogen receptor 1	cellular response to mineralocorticoid stimulus	Biological process	-
HPD	3242	4-hydroxyphenylpyruvate dioxygenase	oxidation-reduction process	Biological process	-
SEC62	7095	SEC62 homolog (S. cerevisiae)	receptor activity	Molecular function	9020021
TEAD2	8463	TEA domain family member 2	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
RPL32	6161	ribosomal protein L32	gene expression	Biological process	-
HMOX1	3162	heme oxygenase 1	negative regulation of DNA binding	Biological process	-
ELK4	2005	ELK4, ETS-domain protein (SRF accessory protein 1)	sequence-specific DNA binding RNA polymerase II transcription factor activity	Molecular function	-
HIST1H4F	8361	histone cluster 1, H4f	DNA replication-independent nucleosome assembly	Biological process	14718166
CNOT7	29883	CCR4-NOT transcription complex, subunit 7	negative regulation of gene expression	Biological process	25038453
NXF1	10482	nuclear RNA export factor 1	nucleoplasm	Cellular component	-
SREBF2	6721	sterol regulatory element binding transcription factor 2	nucleolus	Cellular component	-
CDKL1	8814	cyclin-dependent kinase-like 1 (CDC2-related kinase)	extracellular exosome	Cellular component	18570454
MAD2L2	10459	MAD2 mitotic arrest deficient-like 2 (yeast)	negative regulation of APC-Cdc20 complex activity	Biological process	11459826
ARFGEF2	10564	ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)	Golgi membrane	Cellular component	10716990
ZNF765	91661	zinc finger protein 765	nucleus	Cellular component	-
SNAPC4	6621	small nuclear RNA activating complex, polypeptide 4, 190kDa	transcription from RNA polymerase III promoter	Biological process	-
LMF1	64788	lipase maturation factor 1	ER to Golgi vesicle-mediated transport	Biological process	-
IGF2	3481	insulin-like growth factor 2	female pregnancy	Biological process	-
ARHGEF11	9826	Rho guanine nucleotide exchange factor (GEF) 11	cytosol	Cellular component	-
WNT1	7471	wingless-type MMTV integration site family, member 1	negative regulation of cell-substrate adhesion	Biological process	16501043
ANGPT1	284	angiopoietin 1	receptor tyrosine kinase binding	Molecular function	19922791
DIRAS3	9077	DIRAS family, GTP-binding RAS-like 3	GTPase activity	Molecular function	9874798
TGFB3	7043	transforming growth factor, beta 3	activation of MAPK activity	Biological process	-
TGFBR2	7048	transforming growth factor, beta receptor II (70/80kDa)	SMAD binding	Molecular function	11157754
SRM	6723	spermidine synthase	polyamine metabolic process	Biological process	-
NFX1	4799	nuclear transcription factor, X-box binding 1	nucleus	Cellular component	-
OR2G2	81470	olfactory receptor, family 2, subfamily G, member 2	sensory perception of smell	Biological process	-
MGAT4B	11282	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity	Molecular function	-
CCNA1	8900	cyclin A1	nucleoplasm	Cellular component	-
PKD1L3	342372	polycystic kidney disease 1-like 3	cation transport	Biological process	-
MAPK14	1432	mitogen-activated protein kinase 14	peptidyl-serine phosphorylation	Biological process	-
RIPK2	8767	receptor-interacting serine-threonine kinase 2	JNK cascade	Biological process	-
TLR4	7099	toll-like receptor 4	positive regulation of tumor necrosis factor production	Biological process	-
HMGA2	8091	high mobility group AT-hook 2	DNA damage response, detection of DNA damage	Biological process	19465398
OR10J6P	401973	olfactory receptor, family 10, subfamily J, member 6 pseudogene	olfactory receptor activity	Molecular function	-
RASGRP2	10235	RAS guanyl releasing protein 2 (calcium and DAG-regulated)	regulation of cell growth	Biological process	10918068
YWHAG	7532	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	Biological process	-
EMP2	2013	epithelial membrane protein 2	cell death	Biological process	12107182
NUP85	79902	nucleoporin 85kDa	small molecule metabolic process	Biological process	-
PIF1	80119	PIF1 5'-to-3' DNA helicase	ATP binding	Molecular function	16522649
SLC20A1	6574	solute carrier family 20 (phosphate transporter), member 1	transmembrane transport	Biological process	-
CASP3	836	caspase 3, apoptosis-related cysteine peptidase	intrinsic apoptotic signaling pathway	Biological process	-
SYNE1	23345	spectrin repeat containing, nuclear envelope 1	nuclear matrix anchoring at nuclear membrane	Biological process	11801724
CCL2	6347	chemokine (C-C motif) ligand 2	cellular response to interleukin-1	Biological process	-
PPBP	5473	pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)	positive regulation of leukocyte chemotaxis	Biological process	-
DOCK7	85440	dedicator of cytokinesis 7	focal adhesion	Cellular component	21423176
DPYS	1807	dihydropyrimidinase	pyrimidine nucleoside catabolic process	Biological process	-
PRKAA1	5562	protein kinase, AMP-activated, alpha 1 catalytic subunit	positive regulation of gene expression	Biological process	17028174
RPL27	6155	ribosomal protein L27	focal adhesion	Cellular component	21423176
FLNA	2316	filamin A, alpha	actin filament binding	Molecular function	2391361
PRAMEF1	65121	PRAME family member 1	negative regulation of retinoic acid receptor signaling pathway	Biological process	-
YAP1	10413	Yes-associated protein 1	proline-rich region binding	Molecular function	-
CYP4A11	1579	cytochrome P450, family 4, subfamily A, polypeptide 11	endoplasmic reticulum membrane	Cellular component	-
HSPD1	3329	heat shock 60kDa protein 1 (chaperonin)	activation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	17823127
P3H2	55214	prolyl 3-hydroxylase 2	extracellular matrix organization	Biological process	-
CDKN2C	1031	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	cytosol	Cellular component	-
PLD1	5337	phospholipase D1, phosphatidylcholine-specific	Golgi membrane	Cellular component	-
IP6K1	9807	inositol hexakisphosphate kinase 1	nucleus	Cellular component	-
ETV2	2116	ets variant 2	transcription from RNA polymerase II promoter	Biological process	-
NETO1	81832	neuropilin (NRP) and tolloid (TLL)-like 1	visual learning	Biological process	-
GRM3	2913	glutamate receptor, metabotropic 3	dendritic spine	Cellular component	-
SH3GL2	6456	SH3-domain GRB2-like 2	regulation of receptor internalization	Biological process	-
SHOX	6473	short stature homeobox	skeletal system development	Biological process	9590292
WRNIP1	56897	Werner helicase interacting protein 1	protein binding	Molecular function	15670210
TSC22D3	1831	TSC22 domain family, member 3	protein binding	Molecular function	25416956
SCAND2P	54581	SCAN domain containing 2 pseudogene	biological_process	Biological process	-
NR0B1	190	nuclear receptor subfamily 0, group B, member 1	protein homodimerization activity	Molecular function	16709599
PTPDC1	138639	protein tyrosine phosphatase domain containing 1	protein tyrosine phosphatase activity	Molecular function	-
GNAT3	346562	guanine nucleotide binding protein, alpha transducing 3	acrosomal vesicle	Cellular component	-
IL2RB	3560	interleukin 2 receptor, beta	integral component of plasma membrane	Cellular component	8514792
CHRNA6	8973	cholinergic receptor, nicotinic, alpha 6 (neuronal)	regulation of dopamine secretion	Biological process	-
USP17L5	728386	ubiquitin specific peptidase 17-like family member 5	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological process	-
COMMD1	150684	copper metabolism (Murr1) domain containing 1	protein binding	Molecular function	14645214
TAF7	6879	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa	vitamin D receptor binding	Molecular function	10409738
SRI	6717	sorcin	negative regulation of heart rate	Biological process	12754254
P2RX1	5023	purinergic receptor P2X, ligand gated ion channel, 1	postsynaptic membrane	Cellular component	-
HIF1A	3091	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	positive regulation of transcription from RNA polymerase II promoter in response to hypoxia	Biological process	19652095
MELK	9833	maternal embryonic leucine zipper kinase	neural precursor cell proliferation	Biological process	-
STAT3	6774	signal transducer and activator of transcription 3 (acute-phase response factor)	protein phosphatase binding	Molecular function	12359225
NR1I3	9970	nuclear receptor subfamily 1, group I, member 3	steroid hormone mediated signaling pathway	Biological process	-
OR8D2	283160	olfactory receptor, family 8, subfamily D, member 2 (gene/pseudogene)	sensory perception of smell	Biological process	-
RARRES2	5919	retinoic acid receptor responder (tazarotene induced) 2	extracellular exosome	Cellular component	23376485
SH3BP4	23677	SH3-domain binding protein 4	cytoplasm	Cellular component	22575674
TJP1	7082	tight junction protein 1	sensory perception of sound	Biological process	-
WNT5A	7474	wingless-type MMTV integration site family, member 5A	positive regulation of type I interferon-mediated signaling pathway	Biological process	19399181
ACTL9	284382	actin-like 9	cytoskeleton	Cellular component	-
SLC25A5	292	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5	chromosome segregation	Biological process	-
GFI1	2672	growth factor independent 1 transcription repressor	mechanosensory behavior	Biological process	-
SLC22A9	114571	solute carrier family 22 (organic anion transporter), member 9	sodium-independent organic anion transport	Biological process	17393504
PRPF4	9128	pre-mRNA processing factor 4	U4 snRNA binding	Molecular function	-
GNAT1	2779	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1	retina development in camera-type eye	Biological process	-
SOX13	9580	SRY (sex determining region Y)-box 13	sequence-specific DNA binding transcription factor activity	Molecular function	10198172
NKX2-3	159296	NK2 homeobox 3	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
DNAJA3	9093	DnaJ (Hsp40) homolog, subfamily A, member 3	positive regulation of T cell proliferation	Biological process	-
KATNA1	11104	katanin p60 (ATPase containing) subunit A 1	ATP binding	Molecular function	-
IGHG3	3502	immunoglobulin heavy constant gamma 3 (G3m marker)	extracellular region	Cellular component	-
LTF	4057	lactotransferrin	negative regulation by host of viral process	Biological process	12522210
RCHY1	25898	ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase	ubiquitin-protein transferase activity	Molecular function	-
NAT8	9027	N-acetyltransferase 8 (GCN5-related, putative)	endoplasmic reticulum membrane	Cellular component	20392701
SIRT2	22933	sirtuin 2	myelination in peripheral nervous system	Biological process	-
PTS	5805	6-pyruvoyltetrahydropterin synthase	cytosol	Cellular component	-
APBB3	10307	amyloid beta (A4) precursor protein-binding, family B, member 3	nucleus	Cellular component	-
SIRT1	23411	sirtuin 1	pyrimidine dimer repair by nucleotide-excision repair	Biological process	21149730
LATS2	26524	large tumor suppressor kinase 2	cellular protein localization	Biological process	-
PLEKHH2	130271	pleckstrin homology domain containing, family H (with MyTH4 domain) member 2	protein binding	Molecular function	25416956
TRAF6	7189	TNF receptor-associated factor 6, E3 ubiquitin protein ligase	cytoplasm	Cellular component	16378096
HIST1H4K	8362	histone cluster 1, H4k	protein binding	Molecular function	10220385
GEMIN4	50628	gem (nuclear organelle) associated protein 4	cytoplasm	Cellular component	10725331
MAGEA2	4101	melanoma antigen family A2	ubiquitin protein ligase binding	Molecular function	20864041
JAM3	83700	junctional adhesion molecule 3	myelination	Biological process	-
DMTN	2039	dematin actin binding protein	actin filament capping	Biological process	-
ANKRD27	84079	ankyrin repeat domain 27 (VPS9 domain)	melanosome	Cellular component	-
CAD	790	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	cellular response to epidermal growth factor stimulus	Biological process	-
RICTOR	253260	RPTOR independent companion of MTOR, complex 2	TOR signaling	Biological process	-
RYR1	6261	ryanodine receptor 1 (skeletal)	plasma membrane	Cellular component	11206130
CCNB1IP1	57820	cyclin B1 interacting protein 1, E3 ubiquitin protein ligase	chiasma assembly	Biological process	-
FAM178A	55719	family with sequence similarity 178, member A	extracellular space	Cellular component	22664934
RBP4	5950	retinol binding protein 4, plasma	response to retinoic acid	Biological process	571335
RABGGTB	5876	Rab geranylgeranyltransferase, beta subunit	cellular protein modification process	Biological process	8380507
ACSL6	23305	acyl-CoA synthetase long-chain family member 6	response to steroid hormone	Biological process	-
BIRC3	330	baculoviral IAP repeat containing 3	zinc ion binding	Molecular function	-
SALL1	6299	spalt-like transcription factor 1	outer ear morphogenesis	Biological process	9425907
ASB2	51676	ankyrin repeat and SOCS box containing 2	myoblast differentiation	Biological process	-
MOGAT2	80168	monoacylglycerol O-acyltransferase 2	2-acylglycerol O-acyltransferase activity	Molecular function	-
TLR2	7097	toll-like receptor 2	toll-like receptor TLR1:TLR2 signaling pathway	Biological process	-
HOXB7	3217	homeobox B7	anterior/posterior pattern specification	Biological process	-
APOH	350	apolipoprotein H (beta-2-glycoprotein I)	regulation of fibrinolysis	Biological process	16480936
ZNF878	729747	zinc finger protein 878	transcription, DNA-templated	Biological process	-
TAL1	6886	T-cell acute lymphocytic leukemia 1	embryonic hemopoiesis	Biological process	-
ZNF441	126068	zinc finger protein 441	nucleus	Cellular component	-
TLN1	7094	talin 1	ruffle membrane	Cellular component	-
ADAM8	101	ADAM metallopeptidase domain 8	lymphocyte chemotaxis	Biological process	-
NOD2	64127	nucleotide-binding oligomerization domain containing 2	TRIF-dependent toll-like receptor signaling pathway	Biological process	-
CNTN2	6900	contactin 2 (axonal)	integral component of plasma membrane	Cellular component	8425542
SREBF1	6720	sterol regulatory element binding transcription factor 1	response to progesterone	Biological process	-
ACOT4	122970	acyl-CoA thioesterase 4	long-chain fatty acid metabolic process	Biological process	16940157
CD8B	926	CD8b molecule	early endosome membrane	Cellular component	-
NPTN	27020	neuroplastin	integral component of membrane	Cellular component	-
GPSM3	63940	G-protein signaling modulator 3	molecular_function	Molecular function	-
HLA-B	3106	major histocompatibility complex, class I, B	endoplasmic reticulum	Cellular component	-
BYSL	705	bystin-like	intracellular membrane-bounded organelle	Cellular component	-
ARHGAP21	57584	Rho GTPase activating protein 21	positive regulation of GTPase activity	Biological process	-
MAP7D3	79649	MAP7 domain containing 3	actin cytoskeleton	Cellular component	-
MAP2K3	5606	mitogen-activated protein kinase kinase 3	toll-like receptor TLR6:TLR2 signaling pathway	Biological process	-
SAP18	10284	Sin3A-associated protein, 18kDa	mRNA processing	Biological process	-
BLID	414899	BH3-like motif containing, cell death inducer	mitochondrion	Cellular component	-
PRKX	5613	protein kinase, X-linked	endothelial cell migration	Biological process	21684272
PRKCB	5579	protein kinase C, beta	vascular endothelial growth factor receptor signaling pathway	Biological process	-
PRDM4	11108	PR domain containing 4	negative regulation of cell cycle	Biological process	-
VDR	7421	vitamin D (1,25- dihydroxyvitamin D3) receptor	protein binding	Molecular function	10409738
ARHGAP10	79658	Rho GTPase activating protein 10	small GTPase mediated signal transduction	Biological process	-
GAS2L3	283431	growth arrest-specific 2 like 3	actin cytoskeleton organization	Biological process	21561867
MEGF8	1954	multiple EGF-like-domains 8	craniofacial suture morphogenesis	Biological process	23063620
FGFR2	2263	fibroblast growth factor receptor 2	regulation of ERK1 and ERK2 cascade	Biological process	-
SETD2	29072	SET domain containing 2	histone H3-K36 trimethylation	Biological process	19141475
CST3	1471	cystatin C	response to estradiol	Biological process	-
GPR183	1880	G protein-coupled receptor 183	plasma membrane	Cellular component	21673108
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	androgen receptor binding	Molecular function	15572661
PDS5A	23244	PDS5 cohesin associated factor A	plasma membrane	Cellular component	-
AHCTF1	25909	AT hook containing transcription factor 1	extracellular exosome	Cellular component	19056867
PID1	55022	phosphotyrosine interaction domain containing 1	negative regulation of establishment of protein localization to plasma membrane	Biological process	19079291
ALOX5	240	arachidonate 5-lipoxygenase	extracellular space	Cellular component	22664934
PRLR	5618	prolactin receptor	regulation of epithelial cell differentiation	Biological process	-
APCS	325	amyloid P component, serum	negative regulation by host of viral glycoprotein metabolic process	Biological process	23544079
CTH	1491	cystathionine gamma-lyase	protein homotetramerization	Biological process	19019829
TBC1D10A	83874	TBC1 domain family, member 10A	regulation of cilium assembly	Biological process	17646400
NOTCH1	4851	notch 1	negative regulation of BMP signaling pathway	Biological process	-
IDE	3416	insulin-degrading enzyme	peptide binding	Molecular function	20082125
HIST1H2BH	8345	histone cluster 1, H2bh	DNA binding	Molecular function	9119399
HOXA2	3199	homeobox A2	nucleoplasm	Cellular component	-
DIS3L	115752	DIS3 like exosome 3'-5' exoribonuclease	RNA binding	Molecular function	-
ANKS1A	23294	ankyrin repeat and sterile alpha motif domain containing 1A	protein binding	Molecular function	16273093
AHCYL1	10768	adenosylhomocysteinase-like 1	angiotensin-activated signaling pathway	Biological process	20584908
NF1	4763	neurofibromin 1	sympathetic nervous system development	Biological process	-
HTR3E	285242	5-hydroxytryptamine (serotonin) receptor 3E, ionotropic	serotonin receptor activity	Molecular function	17392525
RNF138	51444	ring finger protein 138, E3 ubiquitin protein ligase	Wnt signaling pathway	Biological process	-
PRAME	23532	preferentially expressed antigen in melanoma	protein binding	Molecular function	16179254
MARCO	8685	macrophage receptor with collagenous structure	endocytic vesicle membrane	Cellular component	-
PRKAG2	51422	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	transcription initiation from RNA polymerase II promoter	Biological process	-
NPHS2	7827	nephrosis 2, idiopathic, steroid-resistant (podocin)	protein complex	Cellular component	17675666
EXOSC10	5394	exosome component 10	poly(A) RNA binding	Molecular function	22658674
OAZ1	4946	ornithine decarboxylase antizyme 1	polyamine biosynthetic process	Biological process	-
RNF181	51255	ring finger protein 181	ubiquitin-protein transferase activity	Molecular function	24105792
PKD2	5311	polycystic kidney disease 2 (autosomal dominant)	nonmotile primary cilium	Cellular component	-
BCAS3	54828	breast carcinoma amplified sequence 3	nucleus	Cellular component	17505058
PRELID1	27166	PRELI domain containing 1	regulation of membrane lipid distribution	Biological process	23931759
ZNF12	7559	zinc finger protein 12	DNA binding	Molecular function	-
DOCK1	1793	dedicator of cytokinesis 1	apoptotic process	Biological process	-
TCFL5	10732	transcription factor-like 5 (basic helix-loop-helix)	transcription from RNA polymerase II promoter	Biological process	9763657
SYTL2	54843	synaptotagmin-like 2	calcium ion binding	Molecular function	-
CCNK	8812	cyclin K	RNA polymerase II carboxy-terminal domain kinase activity	Molecular function	9632813
FCGR2C	9103	Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)	cytoplasm	Cellular component	-
RPS6KA5	9252	ribosomal protein S6 kinase, 90kDa, polypeptide 5	inflammatory response	Biological process	-
MPDZ	8777	multiple PDZ domain protein	postsynaptic density	Cellular component	-
PI4K2A	55361	phosphatidylinositol 4-kinase type 2 alpha	cell junction	Cellular component	-
TPM1	7168	tropomyosin 1 (alpha)	ruffle organization	Biological process	15897890
STX1A	6804	syntaxin 1A (brain)	small molecule metabolic process	Biological process	-
DDX51	317781	DEAD (Asp-Glu-Ala-Asp) box polypeptide 51	membrane	Cellular component	19946888
SULF1	23213	sulfatase 1	negative regulation of endothelial cell proliferation	Biological process	16778174
TNK2	10188	tyrosine kinase, non-receptor, 2	nucleus	Cellular component	20333297
HSD3B2	3284	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2	3-beta-hydroxy-delta5-steroid dehydrogenase activity	Molecular function	1944309
MBTPS1	8720	membrane-bound transcription factor peptidase, site 1	endoplasmic reticulum membrane	Cellular component	-
PPAP2A	8611	phosphatidic acid phosphatase type 2A	germ cell migration	Biological process	9305923
ARAP1	116985	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1	regulation of cell shape	Biological process	11804590
SCN3A	6328	sodium channel, voltage gated, type III alpha subunit	cytoplasm	Cellular component	-
CRK	1398	v-crk avian sarcoma virus CT10 oncogene homolog	SH2 domain binding	Molecular function	9472046
CNOT10	25904	CCR4-NOT transcription complex, subunit 10	regulation of transcription, DNA-templated	Biological process	-
NSDHL	50814	NAD(P) dependent steroid dehydrogenase-like	smoothened signaling pathway	Biological process	-
CDC42EP3	10602	CDC42 effector protein (Rho GTPase binding) 3	actin cytoskeleton	Cellular component	-
SUZ12	23512	SUZ12 polycomb repressive complex 2 subunit	chromatin organization	Biological process	-
Mar-03	115123	membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase	zinc ion binding	Molecular function	-
CMPK1	51727	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic	UMP kinase activity	Molecular function	-
APOA5	116519	apolipoprotein A-V	lipoprotein lipase activator activity	Molecular function	18635818
SACM1L	22908	SAC1 suppressor of actin mutations 1-like (yeast)	biological_process	Biological process	-
ERCC3	2071	excision repair cross-complementation group 3	regulation of gene expression, epigenetic	Biological process	-
MTUS1	57509	microtubule associated tumor suppressor 1	cellular response to peptide hormone stimulus	Biological process	-
TDRD6	221400	tudor domain containing 6	chromatoid body	Cellular component	-
LUC7L3	51747	LUC7-like 3 (S. cerevisiae)	poly(A) RNA binding	Molecular function	22658674
RAD18	56852	RAD18 E3 ubiquitin protein ligase	Rad6-Rad18 complex	Cellular component	-
SNX1	6642	sorting nexin 1	endosome membrane	Cellular component	15673616
FBXO4	26272	F-box protein 4	protein binding	Molecular function	16275645
NME2P1	283458	NME/NM23 nucleoside diphosphate kinase 2 pseudogene 1	CTP biosynthetic process	Biological process	-
OR4S2	219431	olfactory receptor, family 4, subfamily S, member 2	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
STT3A	3703	STT3A, subunit of the oligosaccharyltransferase complex (catalytic)	endoplasmic reticulum membrane	Cellular component	-
DNMT3B	1789	DNA (cytosine-5-)-methyltransferase 3 beta	DNA methylation on cytosine	Biological process	-
CXCR4	7852	chemokine (C-X-C motif) receptor 4	growth cone	Cellular component	-
INSL6	11172	insulin-like 6	fertilization	Biological process	-
SMARCA5	8467	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	histone binding	Molecular function	12972596
IGHM	3507	immunoglobulin heavy constant mu	antigen binding	Molecular function	-
PCDHB18P	54660	protocadherin beta 18 pseudogene	integral component of membrane	Cellular component	-
H2BFS	54145	H2B histone family, member S (pseudogene)	protein heterodimerization activity	Molecular function	-
BCL2L14	79370	BCL2-like 14 (apoptosis facilitator)	endomembrane system	Cellular component	-
SRPK1	6732	SRSF protein kinase 1	protein kinase activity	Molecular function	8208298
ALDH1B1	219	aldehyde dehydrogenase 1 family, member B1	ethanol catabolic process	Biological process	-
KLHL1	57626	kelch-like family member 1	actin cytoskeleton organization	Biological process	10888605
ZNF579	163033	zinc finger protein 579	regulation of transcription, DNA-templated	Biological process	-
NUP43	348995	nucleoporin 43kDa	hexose transport	Biological process	-
CMTR2	55783	cap methyltransferase 2	cytoplasm	Cellular component	21310715
APP	351	amyloid beta (A4) precursor protein	extracellular region	Cellular component	-
TAS2R43	259289	taste receptor, type 2, member 43	bitter taste receptor activity	Molecular function	16720576
RAC3	5881	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	protein binding	Molecular function	11956649
PLAA	9373	phospholipase A2-activating protein	inflammatory response	Biological process	-
VPRBP	9730	Vpr (HIV-1) binding protein	protein ubiquitination	Biological process	-
CRTAC1	55118	cartilage acidic protein 1	calcium ion binding	Molecular function	-
NEDD4	4734	neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase	plasma membrane	Cellular component	15126635
SOX9	6662	SRY (sex determining region Y)-box 9	retina development in camera-type eye	Biological process	-
SERPINB4	6318	serpin peptidase inhibitor, clade B (ovalbumin), member 4	regulation of proteolysis	Biological process	7589435
WDHD1	11169	WD repeat and HMG-box DNA binding protein 1	regulation of chromosome organization	Biological process	-
COL11A1	1301	collagen, type XI, alpha 1	embryonic skeletal system morphogenesis	Biological process	-
CD209	30835	CD209 molecule	virion binding	Molecular function	11337487
OR1D2	4991	olfactory receptor, family 1, subfamily D, member 2	intracellular	Cellular component	16820410
HIST1H4B	8366	histone cluster 1, H4b	protein heterotetramerization	Biological process	20498094
WIPI2	26100	WD repeat domain, phosphoinositide interacting 2	protein binding	Molecular function	21575909
XBP1	7494	X-box binding protein 1	positive regulation of protein acetylation	Biological process	25280941
CHD1L	9557	chromodomain helicase DNA binding protein 1-like	nucleoplasm	Cellular component	-
GALR1	2587	galanin receptor 1	negative regulation of adenylate cyclase activity	Biological process	-
DDX6	1656	DEAD (Asp-Glu-Ala-Asp) box helicase 6	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	Biological process	-
HPRT1	3251	hypoxanthine phosphoribosyltransferase 1	IMP metabolic process	Biological process	19527031
SIGIRR	59307	single immunoglobulin and toll-interleukin 1 receptor (TIR) domain	acute-phase response	Biological process	-
LGALS3	3958	lectin, galactoside-binding, soluble, 3	proteinaceous extracellular matrix	Cellular component	-
COL13A1	1305	collagen, type XIII, alpha 1	single organismal cell-cell adhesion	Biological process	10865988
IL1RL2	8808	interleukin 1 receptor-like 2	positive regulation of T cell differentiation	Biological process	-
MLH3	27030	mutL homolog 3	nucleus	Cellular component	10615123
CACNG7	59284	calcium channel, voltage-dependent, gamma subunit 7	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity	Biological process	21172611
HACE1	57531	HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1	protein binding	Molecular function	25026213
COBL	23242	cordon-bleu WH2 repeat protein	neural tube closure	Biological process	-
OR2M7	391196	olfactory receptor, family 2, subfamily M, member 7	plasma membrane	Cellular component	-
SFRP1	6422	secreted frizzled-related protein 1	negative regulation of epithelial cell proliferation	Biological process	19095296
FANCD2	2177	Fanconi anemia, complementation group D2	nucleoplasm	Cellular component	-
ETV6	2120	ets variant 6	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	-
SUMO1	7341	small ubiquitin-like modifier 1	PML body organization	Biological process	-
RPS6KC1	26750	ribosomal protein S6 kinase, 52kDa, polypeptide 1	protein binding	Molecular function	15750338
LPA	4018	lipoprotein, Lp(a)	extrinsic component of plasma membrane	Cellular component	-
FBXO5	26271	F-box protein 5	protein kinase binding	Molecular function	15148369
MYO3A	53904	myosin IIIA	response to stimulus	Biological process	-
SPARC	6678	secreted protein, acidic, cysteine-rich (osteonectin)	response to cadmium ion	Biological process	-
ROCK1	6093	Rho-associated, coiled-coil containing protein kinase 1	apical constriction	Biological process	-
NRBP2	340371	nuclear receptor binding protein 2	cytoplasm	Cellular component	-
FGFR1	2260	fibroblast growth factor receptor 1	protein tyrosine kinase activity	Molecular function	8622701
TELO2	9894	telomere maintenance 2	regulation of TOR signaling	Biological process	23263282
FREM2	341640	FRAS1 related extracellular matrix protein 2	calcium ion binding	Molecular function	-
SH3PXD2A	9644	SH3 and PX domains 2A	cell projection	Cellular component	-
TCF4	6925	transcription factor 4	positive regulation of transcription from RNA polymerase II promoter	Biological process	8978694
FIZ1	84922	FLT3-interacting zinc finger 1	transcription, DNA-templated	Biological process	-
TNFSF13	8741	tumor necrosis factor (ligand) superfamily, member 13	gene expression	Biological process	-
STUB1	10273	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase	ubiquitin conjugating enzyme complex	Cellular component	16307917
NLGN2	57555	neuroligin 2	terminal button organization	Biological process	-
PLA2G4B	100137049	phospholipase A2, group IVB (cytosolic)	calcium-dependent phospholipid binding	Molecular function	10085124
H1F0	3005	H1 histone family, member 0	poly(A) RNA binding	Molecular function	22658674
ZMAT2	153527	zinc finger, matrin-type 2	nucleus	Cellular component	-
HAND1	9421	heart and neural crest derivatives expressed 1	trophectodermal cell differentiation	Biological process	11802795
ACSS1	84532	acyl-CoA synthetase short-chain family member 1	acetyl-CoA biosynthetic process	Biological process	16788062
SLC6A17	388662	solute carrier family 6 (neutral amino acid transporter), member 17	proline transport	Biological process	-
RPL17	6139	ribosomal protein L17	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Biological process	-
KIR2DS1	3806	killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1	plasma membrane	Cellular component	-
FAM20C	56975	family with sequence similarity 20, member C	protein phosphorylation	Biological process	-
ZNF365	22891	zinc finger protein 365	protein binding	Molecular function	16682949
IL1RN	3557	interleukin 1 receptor antagonist	negative regulation of apoptotic process	Biological process	-
RGS1	5996	regulator of G-protein signaling 1	termination of G-protein coupled receptor signaling pathway	Biological process	-
GRIP1	23426	glutamate receptor interacting protein 1	beta-catenin binding	Molecular function	16344550
EIF2AK3	9451	eukaryotic translation initiation factor 2-alpha kinase 3	protein autophosphorylation	Biological process	12086964
FOS	2353	FBJ murine osteosarcoma viral oncogene homolog	conditioned taste aversion	Biological process	-
DLG4	1742	discs, large homolog 4 (Drosophila)	cell junction	Cellular component	-
CLTC	1213	clathrin, heavy chain (Hc)	receptor internalization	Biological process	14985334
TAS2R60	338398	taste receptor, type 2, member 60	sensory perception of bitter taste	Biological process	12584440
CASP5	838	caspase 5, apoptosis-related cysteine peptidase	pyroptosis	Biological process	-
PAX4	5078	paired box 4	retina development in camera-type eye	Biological process	-
SST	6750	somatostatin	extracellular space	Cellular component	9437026
CHGB	1114	chromogranin B	secretory granule	Cellular component	-
SERPINB7	8710	serpin peptidase inhibitor, clade B (ovalbumin), member 7	extracellular space	Cellular component	-
ZNF721	170960	zinc finger protein 721	DNA binding	Molecular function	-
GNAS	2778	GNAS complex locus	female pregnancy	Biological process	10729789
ASCC3	10973	activating signal cointegrator 1 complex subunit 3	DNA repair	Biological process	-
FOXO3	2309	forkhead box O3	sequence-specific DNA binding	Molecular function	10102273
WIZ	58525	widely interspaced zinc finger motifs	nucleus	Cellular component	16702210
EIF3H	8667	eukaryotic translation initiation factor 3, subunit H	translation initiation factor activity	Molecular function	17581632
IL5RA	3568	interleukin 5 receptor, alpha	inflammatory response to antigenic stimulus	Biological process	-
AEBP1	165	AE binding protein 1	negative regulation of transcription from RNA polymerase II promoter	Biological process	15654748
FUT9	10690	fucosyltransferase 9 (alpha (1,3) fucosyltransferase)	Golgi apparatus	Cellular component	11698403
IL15	3600	interleukin 15	cytokine activity	Molecular function	-
CDSN	1041	corneodesmosin	cell-cell junction	Cellular component	9395522
POLR2L	5441	polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa	DNA-directed RNA polymerase III complex	Cellular component	-
RASA4	10156	RAS p21 protein activator 4	cytosol	Cellular component	16009725
TOP1MT	116447	topoisomerase (DNA) I, mitochondrial	replication fork protection complex	Cellular component	-
GABRB2	2561	gamma-aminobutyric acid (GABA) A receptor, beta 2	GABA-A receptor activity	Molecular function	-
OR10Z1	128368	olfactory receptor, family 10, subfamily Z, member 1	olfactory receptor activity	Molecular function	-
RAB39A	54734	RAB39A, member RAS oncogene family	phagosome acidification	Biological process	21255211
METTL21C	196541	methyltransferase like 21C	protein methylation	Biological process	22948820
ELOVL4	6785	ELOVL fatty acid elongase 4	long-chain fatty-acyl-CoA biosynthetic process	Biological process	-
PAX4	5078	paired box 4	DNA binding	Molecular function	9480859
WNT16	51384	wingless-type MMTV integration site family, member 16	cardiac epithelial to mesenchymal transition	Biological process	-
RPS6KB1	6198	ribosomal protein S6 kinase, 70kDa, polypeptide 1	TOR signaling	Biological process	12150926
DNPH1	10591	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	cell proliferation	Biological process	9271375
MAP7D2	256714	MAP7 domain containing 2	structural molecule activity	Molecular function	-
NKX6-3	157848	NK6 homeobox 3	negative regulation of epithelial cell differentiation	Biological process	-
SRC	6714	SRC proto-oncogene, non-receptor tyrosine kinase	cellular response to hypoxia	Biological process	-
LYN	4067	LYN proto-oncogene, Src family tyrosine kinase	mitochondrial crista	Cellular component	-
RPL17	6139	ribosomal protein L17	translation	Biological process	-
SRSF12	135295	serine/arginine-rich splicing factor 12	poly(A) RNA binding	Molecular function	22681889
CYBRD1	79901	cytochrome b reductase 1	protein binding	Molecular function	21516116
SREK1	140890	splicing regulatory glutamine/lysine-rich protein 1	spliceosomal complex	Cellular component	-
HHIP	64399	hedgehog interacting protein	neuroblast proliferation	Biological process	-
THRAP3	9967	thyroid hormone receptor associated protein 3	transcription cofactor activity	Molecular function	12218053
ITGA2	3673	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	positive regulation of positive chemotaxis	Biological process	-
TBATA	219793	thymus, brain and testes associated	multicellular organismal development	Biological process	-
TPTE	7179	transmembrane phosphatase with tensin homology	ion channel activity	Molecular function	-
CD40	958	CD40 molecule, TNF receptor superfamily member 5	plasma membrane	Cellular component	-
ZNF205	7755	zinc finger protein 205	sequence-specific DNA binding transcription factor activity	Molecular function	-
SUSD2	56241	sushi domain containing 2	plasma membrane	Cellular component	23131994
TERT	7015	telomerase reverse transcriptase	RNA binding	Molecular function	19701182
CD164	8763	CD164 molecule, sialomucin	immune response	Biological process	9763543
WNT7A	7476	wingless-type MMTV integration site family, member 7A	negative regulation of neurogenesis	Biological process	12843296
IGKV3-20	28912	immunoglobulin kappa variable 3-20	extracellular space	Cellular component	23398317
GSK3B	2932	glycogen synthase kinase 3 beta	innate immune response	Biological process	-
GLI2	2736	GLI family zinc finger 2	hindgut morphogenesis	Biological process	-
ZBTB14	7541	zinc finger and BTB domain containing 14	negative regulation of transcription, DNA-templated	Biological process	17714511
COL28A1	340267	collagen, type XXVIII, alpha 1	extracellular matrix organization	Biological process	-
GATAD2A	54815	GATA zinc finger domain containing 2A	DNA methylation	Biological process	12183469
NDEL1	81565	nudE neurodevelopment protein 1-like 1	neurofilament cytoskeleton organization	Biological process	-
PTTG1	9232	pituitary tumor-transforming 1	chromosome organization	Biological process	-
CST3	1471	cystatin C	extracellular fibril organization	Biological process	18026102
CEP135	9662	centrosomal protein 135kDa	centriole-centriole cohesion	Biological process	18851962
BTK	695	Bruton agammaglobulinemia tyrosine kinase	positive regulation of B cell differentiation	Biological process	19290921
TBC1D3H	729877	TBC1 domain family, member 3H	positive regulation of GTPase activity	Biological process	-
HES7	84667	hes family bHLH transcription factor 7	mesoderm development	Biological process	11260262
WNT4	54361	wingless-type MMTV integration site family, member 4	embryonic epithelial tube formation	Biological process	-
MALSU1	115416	mitochondrial assembly of ribosomal large subunit 1	negative regulation of mitochondrial translation	Biological process	22829778
SKI	6497	SKI proto-oncogene	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
ANGPTL4	51129	angiopoietin-like 4	response to hypoxia	Biological process	12707035
PSMD4	5710	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	negative regulation of apoptotic process	Biological process	-
SKOR2	652991	SKI family transcriptional corepressor 2	transcription corepressor activity	Molecular function	-
YBX1	4904	Y box binding protein 1	in utero embryonic development	Biological process	-
FGFR2	2263	fibroblast growth factor receptor 2	epidermal growth factor receptor signaling pathway	Biological process	-
USP33	23032	ubiquitin specific peptidase 33	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological process	-
DMRT1	1761	doublesex and mab-3 related transcription factor 1	core promoter proximal region sequence-specific DNA binding	Molecular function	-
DPM1	8813	dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit	protein N-linked glycosylation via asparagine	Biological process	-
MT3	4504	metallothionein 3	protein stabilization	Biological process	18295594
SQSTM1	8878	sequestosome 1	K63-linked polyubiquitin binding	Molecular function	-
RERE	473	arginine-glutamic acid dipeptide (RE) repeats	chromatin remodeling	Biological process	-
NF1	4763	neurofibromin 1	phosphatidylethanolamine binding	Molecular function	17187824
SYVN1	84447	synovial apoptosis inhibitor 1, synoviolin	IRE1-mediated unfolded protein response	Biological process	-
DBF4B	80174	DBF4 zinc finger B	positive regulation of protein kinase activity	Biological process	12065429
ACSS1	84532	acyl-CoA synthetase short-chain family member 1	acetate biosynthetic process	Biological process	-
FGF9	2254	fibroblast growth factor 9	embryonic limb morphogenesis	Biological process	-
NRP1	8829	neuropilin 1	regulation of vesicle-mediated transport	Biological process	21245381
MKL2	57496	MKL/myocardin-like 2	transcription coactivator activity	Molecular function	14565952
RPL34	6164	ribosomal protein L34	viral life cycle	Biological process	-
MATN2	4147	matrilin 2	molecular_function	Molecular function	-
MIF	4282	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	innate immune response	Biological process	-
RPS25	6230	ribosomal protein S25	ribosomal small subunit assembly	Biological process	-
SPTB	6710	spectrin, beta, erythrocytic	intrinsic component of the cytoplasmic side of the plasma membrane	Cellular component	10950304
HEATR1	55127	HEAT repeat containing 1	nucleolus	Cellular component	-
MAP3K11	4296	mitogen-activated protein kinase kinase kinase 11	peptidyl-tyrosine phosphorylation	Biological process	-
MMP24	10893	matrix metallopeptidase 24 (membrane-inserted)	detection of temperature stimulus involved in sensory perception of pain	Biological process	-
ZNF419	79744	zinc finger protein 419	nucleus	Cellular component	-
ZAK	51776	sterile alpha motif and leucine zipper containing kinase AZK	response to stress	Biological process	11836244
SH3TC2	79628	SH3 domain and tetratricopeptide repeats 2	cytoplasmic vesicle	Cellular component	-
AKTIP	64400	AKT interacting protein	ubiquitin protein ligase activity	Molecular function	-
CUBN	8029	cubilin (intrinsic factor-cobalamin receptor)	endoplasmic reticulum	Cellular component	-
ATXN1	6310	ataxin 1	nuclear matrix	Cellular component	17557114
FAM96A	84191	family with sequence similarity 96, member A	molecular_function	Molecular function	-
CDK9	1025	cyclin-dependent kinase 9	gene expression	Biological process	-
PFN1	5216	profilin 1	adenyl-nucleotide exchange factor activity	Molecular function	7758455
SLC25A21	89874	solute carrier family 25 (mitochondrial oxoadipate carrier), member 21	small molecule metabolic process	Biological process	-
HES1	3280	hes family bHLH transcription factor 1	regulation of timing of neuron differentiation	Biological process	-
PSMD14	10213	proteasome (prosome, macropain) 26S subunit, non-ATPase, 14	metallopeptidase activity	Molecular function	19214193
GLB1	2720	galactosidase, beta 1	glycosaminoglycan catabolic process	Biological process	-
TAF5L	27097	TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa	sequence-specific DNA binding transcription factor activity	Molecular function	9674425
MAP2K5	5607	mitogen-activated protein kinase kinase 5	protein kinase activity	Molecular function	7759517
SLC11A1	6556	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1	macrophage activation	Biological process	-
ADGRE1	2015	adhesion G protein-coupled receptor E1	G-protein coupled receptor signaling pathway	Biological process	-
SHMT1	6470	serine hydroxymethyltransferase 1 (soluble)	L-allo-threonine aldolase activity	Molecular function	-
NHEJ1	79840	nonhomologous end-joining factor 1	T cell differentiation	Biological process	16439204
FKBP1A	2280	FK506 binding protein 1A, 12kDa	extracellular matrix	Cellular component	18346205
FBXL2	25827	F-box and leucine-rich repeat protein 2	protein phosphatase binding	Molecular function	23604317
APC2	10297	adenomatosis polyposis coli 2	actin filament	Cellular component	11691822
SNRNP40	9410	small nuclear ribonucleoprotein 40kDa (U5)	small nucleolar ribonucleoprotein complex	Cellular component	9774689
NEU1	4758	sialidase 1 (lysosomal sialidase)	lipid catabolic process	Biological process	-
MIXL1	83881	Mix paired-like homeobox	core promoter proximal region sequence-specific DNA binding	Molecular function	-
DAB2	1601	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)	clathrin coat assembly	Biological process	-
ACHE	43	acetylcholinesterase (Yt blood group)	glycerophospholipid biosynthetic process	Biological process	-
TRNP1	388610	TMF1-regulated nuclear protein 1	nuclear euchromatin	Cellular component	-
VDR	7421	vitamin D (1,25- dihydroxyvitamin D3) receptor	negative regulation of cell proliferation	Biological process	16549446
CDKN1C	1028	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	regulation of mitotic cell cycle	Biological process	-
SSTR2	6752	somatostatin receptor 2	protein binding	Molecular function	10551867
PSMC4	5704	proteasome (prosome, macropain) 26S subunit, ATPase, 4	blastocyst development	Biological process	-
CNOT10	25904	CCR4-NOT transcription complex, subunit 10	CCR4-NOT complex	Cellular component	19558367
POMP	51371	proteasome maturation protein	protein binding	Molecular function	14733938
TP53BP2	7159	tumor protein p53 binding protein 2	embryo development ending in birth or egg hatching	Biological process	-
OR4P4	81300	olfactory receptor, family 4, subfamily P, member 4	olfactory receptor activity	Molecular function	-
MLLT4	4301	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	cytosol	Cellular component	-
RAPGEF4	11069	Rap guanine nucleotide exchange factor (GEF) 4	regulation of exocytosis	Biological process	-
DDX5	1655	DEAD (Asp-Glu-Ala-Asp) box helicase 5	nucleoplasm	Cellular component	-
PTPN11	5781	protein tyrosine phosphatase, non-receptor type 11	axon guidance	Biological process	-
TLE3	7090	transducin-like enhancer of split 3	protein binding	Molecular function	17577209
MAP2K1	5604	mitogen-activated protein kinase kinase 1	regulation of Golgi inheritance	Biological process	19565474
BST2	684	bone marrow stromal cell antigen 2	cell surface	Cellular component	-
OR8G5	219865	olfactory receptor, family 8, subfamily G, member 5	olfactory receptor activity	Molecular function	-
STRA8	346673	stimulated by retinoic acid 8	meiotic DNA double-strand break formation	Biological process	-
SPACA3	124912	sperm acrosome associated 3	cell wall macromolecule catabolic process	Biological process	16150577
MYO9B	4650	myosin IXB	metabolic process	Biological process	-
PAK2	5062	p21 protein (Cdc42/Rac)-activated kinase 2	regulation of apoptotic process	Biological process	-
ASPM	259266	asp (abnormal spindle) homolog, microcephaly associated (Drosophila)	neuronal stem cell maintenance	Biological process	-
IRS1	3667	insulin receptor substrate 1	SH2 domain binding	Molecular function	-
ERAP2	64167	endoplasmic reticulum aminopeptidase 2	regulation of blood pressure	Biological process	12799365
SLC1A4	6509	solute carrier family 1 (glutamate/neutral amino acid transporter), member 4	integral component of membrane	Cellular component	8101838
WISP1	8840	WNT1 inducible signaling pathway protein 1	proteinaceous extracellular matrix	Cellular component	-
ARFGEF1	10565	ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)	Golgi apparatus	Cellular component	-
NOD2	64127	nucleotide-binding oligomerization domain containing 2	cytoskeleton	Cellular component	21887730
MCM5	4174	minichromosome maintenance complex component 5	ATP binding	Molecular function	-
KRT85	3891	keratin 85, type II	epidermis development	Biological process	9084137
RAD52	5893	RAD52 homolog (S. cerevisiae)	protein binding	Molecular function	12750383
POLR2L	5441	polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa	RNA splicing	Biological process	-
XIAP	331	X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase	protein binding	Molecular function	11257230
SUV39H1	6839	suppressor of variegation 3-9 homolog 1 (Drosophila)	histone methyltransferase activity (H3-K9 specific)	Molecular function	10949293
CDKN1A	1026	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	negative regulation of cyclin-dependent protein serine/threonine kinase activity	Biological process	-
GSTO2	119391	glutathione S-transferase omega 2	protein binding	Molecular function	25416956
NQO1	1728	NAD(P)H dehydrogenase, quinone 1	superoxide dismutase activity	Molecular function	-
SERHL	94009	serine hydrolase-like (pseudogene)	biological_process	Biological process	-
PSMD9	5715	proteasome (prosome, macropain) 26S subunit, non-ATPase, 9	regulation of cellular amino acid metabolic process	Biological process	-
ANK2	287	ankyrin 2, neuronal	protein binding	Molecular function	15262991
IP6K2	51447	inositol hexakisphosphate kinase 2	nucleus	Cellular component	-
SESTD1	91404	SEC14 and spectrin domains 1	phosphatidylserine binding	Molecular function	20164195
PRKAA2	5563	protein kinase, AMP-activated, alpha 2 catalytic subunit	rhythmic process	Biological process	-
ZNHIT6	54680	zinc finger, HIT-type containing 6	metal ion binding	Molecular function	-
NOD1	10392	nucleotide-binding oligomerization domain containing 1	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	10329646
SRSF9	8683	serine/arginine-rich splicing factor 9	mRNA processing	Biological process	7556075
PROX1	5629	prospero homeobox 1	aorta smooth muscle tissue morphogenesis	Biological process	-
FGFBP3	143282	fibroblast growth factor binding protein 3	heparin binding	Molecular function	18669637
PDGFRB	5159	platelet-derived growth factor receptor, beta polypeptide	positive regulation of MAP kinase activity	Biological process	-
TFAP4	7023	transcription factor AP-4 (activating enhancer binding protein 4)	sequence-specific DNA binding	Molecular function	2123466
WAPAL	23063	wings apart-like homolog (Drosophila)	regulation of chromosome condensation	Biological process	-
FGD5	152273	FYVE, RhoGEF and PH domain containing 5	protein binding	Molecular function	23455924
TP53INP1	94241	tumor protein p53 inducible nuclear protein 1	negative regulation of cell proliferation	Biological process	-
AP1G1	164	adaptor-related protein complex 1, gamma 1 subunit	lysosomal membrane	Cellular component	-
ANXA3	306	annexin A3	specific granule	Cellular component	7526843
HIST1H4H	8365	histone cluster 1, H4h	protein heterodimerization activity	Molecular function	-
CX3CL1	6376	chemokine (C-X3-C motif) ligand 1	cell adhesion	Biological process	-
FGF23	8074	fibroblast growth factor 23	positive regulation of transcription, DNA-templated	Biological process	-
GSK3B	2932	glycogen synthase kinase 3 beta	epidermal growth factor receptor signaling pathway	Biological process	-
NARF	26502	nuclear prelamin A recognition factor	nuclear lamina	Cellular component	10514485
INHA	3623	inhibin, alpha	positive regulation of follicle-stimulating hormone secretion	Biological process	12456957
CLTCL1	8218	clathrin, heavy chain-like 1	extracellular exosome	Cellular component	23533145
MADD	8567	MAP-kinase activating death domain	death receptor binding	Molecular function	9115275
RND3	390	Rho family GTPase 3	actin cytoskeleton organization	Biological process	9531558
SLC4A4	8671	solute carrier family 4 (sodium bicarbonate cotransporter), member 4	sodium:bicarbonate symporter activity	Molecular function	17661077
SLC26A6	65010	solute carrier family 26 (anion exchanger), member 6	protein kinase C signaling	Biological process	15990874
ZFYVE19	84936	zinc finger, FYVE domain containing 19	cell division	Biological process	-
KCNA1	3736	potassium channel, voltage gated shaker related subfamily A, member 1	detection of mechanical stimulus involved in sensory perception of pain	Biological process	-
EDN1	1906	endothelin 1	regulation of sensory perception of pain	Biological process	-
HMGA2	8091	high mobility group AT-hook 2	positive regulation of apoptotic process	Biological process	16061642
ATP1B2	482	ATPase, Na+/K+ transporting, beta 2 polypeptide	sodium ion export from cell	Biological process	10636900
BLMH	642	bleomycin hydrolase	nucleoplasm	Cellular component	-
VASP	7408	vasodilator-stimulated phosphoprotein	cytoplasm	Cellular component	-
KCNIP3	30818	Kv channel interacting protein 3, calsenilin	endoplasmic reticulum	Cellular component	-
FZR1	51343	fizzy/cell division cycle 20 related 1 (Drosophila)	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
TSLP	85480	thymic stromal lymphopoietin	extracellular space	Cellular component	-
ACTB	60	actin, beta	axon	Cellular component	-
ARPP19	10776	cAMP-regulated phosphoprotein, 19kDa	protein phosphatase inhibitor activity	Molecular function	-
DLG4	1742	discs, large homolog 4 (Drosophila)	establishment or maintenance of epithelial cell apical/basal polarity	Biological process	-
CST4	1472	cystatin S	extracellular exosome	Cellular component	19199708
SYTL4	94121	synaptotagmin-like 4	calcium ion binding	Molecular function	-
TRAT1	50852	T cell receptor associated transmembrane adaptor 1	innate immune response	Biological process	-
FZD1	8321	frizzled class receptor 1	membranous septum morphogenesis	Biological process	-
ADCYAP1R1	117	adenylate cyclase activating polypeptide 1 (pituitary) receptor type I	G-protein coupled receptor signaling pathway	Biological process	-
BIRC7	79444	baculoviral IAP repeat containing 7	spindle microtubule	Cellular component	-
EPS15L1	58513	epidermal growth factor receptor pathway substrate 15-like 1	membrane	Cellular component	19946888
TMEM259	91304	transmembrane protein 259	integral component of membrane	Cellular component	-
CCL20	6364	chemokine (C-C motif) ligand 20	positive regulation of interleukin-1 alpha biosynthetic process	Biological process	-
NIT1	4817	nitrilase 1	nitrilase activity	Molecular function	9671749
TERF1	7013	telomeric repeat binding factor (NIMA-interacting) 1	chromatin binding	Molecular function	-
GJA1	2697	gap junction protein, alpha 1, 43kDa	extracellular exosome	Cellular component	23376485
MAP2K1	5604	mitogen-activated protein kinase kinase 1	protein C-terminus binding	Molecular function	22572157
MAL	4118	mal, T-cell differentiation protein	myelination	Biological process	10428054
KRT9	3857	keratin 9, type I	structural constituent of cytoskeleton	Molecular function	8647270
ADAMTS3	9508	ADAM metallopeptidase with thrombospondin type 1 motif, 3	metalloendopeptidase activity	Molecular function	11812023
SLC26A2	1836	solute carrier family 26 (anion exchanger), member 2	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process	Biological process	-
ICAM1	3383	intercellular adhesion molecule 1	cell aging	Biological process	-
PRDM12	59335	PR domain containing 12	nucleus	Cellular component	-
APOB	338	apolipoprotein B	cholesterol metabolic process	Biological process	2563166
ABCB4	5244	ATP-binding cassette, sub-family B (MDR/TAP), member 4	intercellular canaliculus	Cellular component	-
DCLRE1C	64421	DNA cross-link repair 1C	nucleus	Cellular component	-
LECT2	3950	leukocyte cell-derived chemotaxin 2	negative regulation of Wnt signaling pathway	Biological process	-
NDE1	54820	nudE neurodevelopment protein 1	centrosome	Cellular component	21399614
MMP10	4319	matrix metallopeptidase 10	extracellular space	Cellular component	2844164
DSCAML1	57453	Down syndrome cell adhesion molecule like 1	brain development	Biological process	12051741
CDA	978	cytidine deaminase	protein homodimerization activity	Molecular function	15689149
INS	3630	insulin	negative regulation of feeding behavior	Biological process	17957153
USP50	373509	ubiquitin specific peptidase 50	histone deubiquitination	Biological process	-
GALNT2	2590	polypeptide N-acetylgalactosaminyltransferase 2	protein O-linked glycosylation	Biological process	-
PDGFRB	5159	platelet-derived growth factor receptor, beta polypeptide	positive regulation of ERK1 and ERK2 cascade	Biological process	-
CYP4A11	1579	cytochrome P450, family 4, subfamily A, polypeptide 11	arachidonic acid metabolic process	Biological process	-
NCAPD3	23310	non-SMC condensin II complex, subunit D3	nucleoplasm	Cellular component	-
TOMM40	10452	translocase of outer mitochondrial membrane 40 homolog (yeast)	nucleoplasm	Cellular component	-
MKKS	8195	McKusick-Kaufman syndrome	negative regulation of blood pressure	Biological process	-
FLT1	2321	fms-related tyrosine kinase 1	growth factor binding	Molecular function	10471394
EEF1D	1936	eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)	regulation of transcription, DNA-templated	Biological process	-
TNFRSF1B	7133	tumor necrosis factor receptor superfamily, member 1B	tumor necrosis factor-activated receptor activity	Molecular function	-
OGG1	4968	8-oxoguanine DNA glycosylase	depurination	Biological process	-
TPST2	8459	tyrosylprotein sulfotransferase 2	integral component of membrane	Cellular component	-
CDC42EP3	10602	CDC42 effector protein (Rho GTPase binding) 3	cytoskeletal regulatory protein binding	Molecular function	11035016
PGLS	25796	6-phosphogluconolactonase	small molecule metabolic process	Biological process	-
FOXD4L3	286380	forkhead box D4-like 3	sequence-specific DNA binding	Molecular function	-
TIRAP	114609	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	protein binding, bridging	Molecular function	19509286
PRIM1	5557	primase, DNA, polypeptide 1 (49kDa)	DNA primase activity	Molecular function	-
SLC2A1	6513	solute carrier family 2 (facilitated glucose transporter), member 1	kinase binding	Molecular function	-
CHMP4B	128866	charged multivesicular body protein 4B	negative regulation of cell death	Biological process	20616062
SPRY3	10251	sprouty homolog 3 (Drosophila)	axon development	Biological process	-
DPM3	54344	dolichyl-phosphate mannosyltransferase polypeptide 3	protein binding	Molecular function	10835346
RAB8A	4218	RAB8A, member RAS oncogene family	protein secretion	Biological process	-
PHC1	1911	polyhomeotic homolog 1 (Drosophila)	nuclear body	Cellular component	-
ANP32A	8125	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	cytoplasm	Cellular component	11729309
PCDHGC5	56097	protocadherin gamma subfamily C, 5	integral component of membrane	Cellular component	-
DMRTA1	63951	DMRT-like family A1	metal ion binding	Molecular function	-
FER	2241	fer (fps/fes related) tyrosine kinase	negative regulation of mast cell activation involved in immune response	Biological process	-
APOH	350	apolipoprotein H (beta-2-glycoprotein I)	lipoprotein lipase activator activity	Molecular function	7417307
CAMK2D	817	calcium/calmodulin-dependent protein kinase II delta	cellular potassium ion homeostasis	Biological process	-
ATP2B3	492	ATPase, Ca++ transporting, plasma membrane 3	calcium-transporting ATPase activity	Molecular function	-
HIST1H4F	8361	histone cluster 1, H4f	poly(A) RNA binding	Molecular function	22658674
HYAL2	8692	hyaluronoglucosaminidase 2	perinuclear region of cytoplasm	Cellular component	16600643
SLC9A1	6548	solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1	nucleoplasm	Cellular component	-
PICALM	8301	phosphatidylinositol binding clathrin assembly protein	endosomal transport	Biological process	16262731
SH3GL3	6457	SH3-domain GRB2-like 3	endocytosis	Biological process	-
BBS7	55212	Bardet-Biedl syndrome 7	protein localization	Biological process	-
USP17L18	100287364	ubiquitin specific peptidase 17-like family member 18	cysteine-type endopeptidase activity	Molecular function	-
CSF1R	1436	colony stimulating factor 1 receptor	innate immune response	Biological process	-
DDC	1644	dopa decarboxylase (aromatic L-amino acid decarboxylase)	amino acid binding	Molecular function	-
GCDH	2639	glutaryl-CoA dehydrogenase	small molecule metabolic process	Biological process	-
NLGN1	22871	neuroligin 1	extracellular space	Cellular component	-
MLXIPL	51085	MLX interacting protein-like	positive regulation of transcription from RNA polymerase II promoter	Biological process	11230181
CHRDL1	91851	chordin-like 1	ossification	Biological process	-
SEMA5A	9037	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	positive regulation of endothelial cell proliferation	Biological process	-
CABP4	57010	calcium binding protein 4	phototransduction	Biological process	-
NLGN4X	57502	neuroligin 4, X-linked	cell adhesion molecule binding	Molecular function	18923512
ZNF746	155061	zinc finger protein 746	protein binding	Molecular function	21376232
PTTG1IP	754	pituitary tumor-transforming 1 interacting protein	protein import into nucleus	Biological process	10781616
ACHE	43	acetylcholinesterase (Yt blood group)	receptor internalization	Biological process	-
NOTCH2	4853	notch 2	receptor complex	Cellular component	23382219
FZD4	8322	frizzled class receptor 4	plasma membrane	Cellular component	-
ARL6	84100	ADP-ribosylation factor-like 6	protein binding	Molecular function	20603001
FKBPL	63943	FK506 binding protein like	endoplasmic reticulum membrane	Cellular component	-
CEP131	22994	centrosomal protein 131kDa	cell differentiation	Biological process	-
NCOA3	8202	nuclear receptor coactivator 3	mammary gland branching involved in thelarche	Biological process	-
NFKBIB	4793	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	nucleus	Cellular component	-
KIF4A	24137	kinesin family member 4A	blood coagulation	Biological process	-
PDGFB	5155	platelet-derived growth factor beta polypeptide	Fc-epsilon receptor signaling pathway	Biological process	-
APOD	347	apolipoprotein D	negative regulation of monocyte chemotactic protein-1 production	Biological process	18842892
SCN8A	6334	sodium channel, voltage gated, type VIII alpha subunit	neuromuscular process	Biological process	-
RYR2	6262	ryanodine receptor 2 (cardiac)	response to caffeine	Biological process	17921453
TAF5	6877	TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa	chromatin modification	Biological process	10373431
NPHP3	27031	nephronophthisis 3 (adolescent)	epithelial cilium movement involved in determination of left/right asymmetry	Biological process	-
MIF	4282	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	chemoattractant activity	Molecular function	19602265
ATP4B	496	ATPase, H+/K+ exchanging, beta polypeptide	cell adhesion	Biological process	-
WASF1	8936	WAS protein family, member 1	lamellipodium	Cellular component	-
PHOSPHO1	162466	phosphatase, orphan 1	cytosol	Cellular component	-
FADS2	9415	fatty acid desaturase 2	integral component of plasma membrane	Cellular component	9867867
GLTP	51228	glycolipid transfer protein	sphingolipid metabolic process	Biological process	-
ZNF260	339324	zinc finger protein 260	nucleoplasm	Cellular component	-
CHMP1A	5119	charged multivesicular body protein 1A	cell separation after cytokinesis	Biological process	20616062
SLC24A2	25769	solute carrier family 24 (sodium/potassium/calcium exchanger), member 2	long term synaptic depression	Biological process	-
CNTFR	1271	ciliary neurotrophic factor receptor	extrinsic component of membrane	Cellular component	1648265
CDKN1C	1028	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	embryonic placenta morphogenesis	Biological process	-
HOMER3	9454	homer scaffolding protein 3	plasma membrane	Cellular component	-
MICALL2	79778	MICAL-like 2	adherens junction assembly	Biological process	-
SIX1	6495	SIX homeobox 1	pharyngeal system development	Biological process	-
SOX5	6660	SRY (sex determining region Y)-box 5	sequence-specific DNA binding transcription factor activity	Molecular function	8812465
SLC30A9	10463	solute carrier family 30 (zinc transporter), member 9	ligand-dependent nuclear receptor binding	Molecular function	-
CYTH4	27128	cytohesin 4	positive regulation of GTPase activity	Biological process	-
CENPW	387103	centromere protein W	mitotic nuclear division	Biological process	-
NOC2L	26155	nucleolar complex associated 2 homolog (S. cerevisiae)	cellular response to UV	Biological process	20959462
ATG4A	115201	autophagy related 4A, cysteine peptidase	cysteine-type endopeptidase activity	Molecular function	-
MEF2A	4205	myocyte enhancer factor 2A	innate immune response	Biological process	-
GCH1	2643	GTP cyclohydrolase 1	protein heterooligomerization	Biological process	-
SLC11A2	4891	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2	vacuole	Cellular component	17932044
DNAJB13	374407	DnaJ (Hsp40) homolog, subfamily B, member 13	unfolded protein binding	Molecular function	-
MDH2	4191	malate dehydrogenase 2, NAD (mitochondrial)	small molecule metabolic process	Biological process	-
MSH3	4437	mutS homolog 3	membrane	Cellular component	19946888
PLCG2	5336	phospholipase C, gamma 2 (phosphatidylinositol-specific)	inositol trisphosphate biosynthetic process	Biological process	-
PTCH1	5727	patched 1	heparin binding	Molecular function	-
OR7G1	125962	olfactory receptor, family 7, subfamily G, member 1	G-protein coupled receptor activity	Molecular function	-
TEAD3	7005	TEA domain family member 3	female pregnancy	Biological process	9148898
SCAI	286205	suppressor of cancer cell invasion	cytoplasm	Cellular component	-
SEMA3C	10512	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	blood vessel remodeling	Biological process	-
ATP6V0E2	155066	ATPase, H+ transporting V0 subunit e2	vacuolar acidification	Biological process	-
ETV6	2120	ets variant 6	protein binding	Molecular function	12590135
MYC	4609	v-myc avian myelocytomatosis viral oncogene homolog	protein binding	Molecular function	10597290
COL6A3	1293	collagen, type VI, alpha 3	extracellular matrix organization	Biological process	-
PDIA4	9601	protein disulfide isomerase family A, member 4	poly(A) RNA binding	Molecular function	22658674
HIATL1	84641	hippocampus abundant transcript-like 1	transporter activity	Molecular function	-
FGF8	2253	fibroblast growth factor 8 (androgen-induced)	corticotropin hormone secreting cell differentiation	Biological process	-
EZH2	2146	enhancer of zeste 2 polycomb repressive complex 2 subunit	protein-lysine N-methyltransferase activity	Molecular function	-
P2RX7	5027	purinergic receptor P2X, ligand gated ion channel, 7	negative regulation of cell volume	Biological process	25651887
GGPS1	9453	geranylgeranyl diphosphate synthase 1	dimethylallyltranstransferase activity	Molecular function	-
GATA6	2627	GATA binding protein 6	organ formation	Biological process	-
RNASEL	6041	ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)	transmembrane transport	Biological process	-
TMEM8B	51754	transmembrane protein 8B	endoplasmic reticulum	Cellular component	-
SPACA4	171169	sperm acrosome associated 4	anchored component of membrane	Cellular component	-
RDH5	5959	retinol dehydrogenase 5 (11-cis/9-cis)	cell body	Cellular component	-
PEX13	5194	peroxisomal biogenesis factor 13	neuron migration	Biological process	-
WFDC1	58189	WAP four-disulfide core domain 1	response to estradiol	Biological process	-
HCRT	3060	hypocretin (orexin) neuropeptide precursor	positive regulation of calcium ion transport	Biological process	-
CD226	10666	CD226 molecule	integral component of plasma membrane	Cellular component	8673704
NUDT11	55190	nudix (nucleoside diphosphate linked moiety X)-type motif 11	small molecule metabolic process	Biological process	-
PIK3CG	5294	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	plasma membrane	Cellular component	-
THAP11	57215	THAP domain containing 11	zinc ion binding	Molecular function	23306615
NR1H4	9971	nuclear receptor subfamily 1, group H, member 4	response to lipopolysaccharide	Biological process	-
PTPN14	5784	protein tyrosine phosphatase, non-receptor type 14	cytoskeleton	Cellular component	-
LPCAT1	79888	lysophosphatidylcholine acyltransferase 1	1-alkylglycerophosphocholine O-acyltransferase activity	Molecular function	-
GFI1	2672	growth factor independent 1 transcription repressor	negative regulation of NF-kappaB transcription factor activity	Biological process	-
GLYATL1	92292	glycine-N-acyltransferase-like 1	glutamine N-acyltransferase activity	Molecular function	-
VLDLR	7436	very low density lipoprotein receptor	glycoprotein transporter activity	Molecular function	10571240
FCN3	8547	ficolin (collagen/fibrinogen domain containing) 3	defense response to virus	Biological process	22851708
PLXNA4	91584	plexin A4	sympathetic nervous system development	Biological process	-
UBB	7314	ubiquitin B	negative regulation of epidermal growth factor receptor signaling pathway	Biological process	-
OSBPL7	114881	oxysterol binding protein-like 7	lipid transport	Biological process	-
PARVG	64098	parvin, gamma	actin binding	Molecular function	11171322
NBEAL1	65065	neurobeachin-like 1	intracellular	Cellular component	-
DNAH3	55567	dynein, axonemal, heavy chain 3	axonemal dynein complex	Cellular component	9256245
ZNF628	89887	zinc finger protein 628	regulation of transcription, DNA-templated	Biological process	-
DES	1674	desmin	sarcolemma	Cellular component	25394388
MOV10	4343	Mov10 RISC complex RNA helicase	Notch signaling pathway	Biological process	-
CUL5	8065	cullin 5	protein heterodimerization activity	Molecular function	-
F2R	2149	coagulation factor II (thrombin) receptor	positive regulation of MAPK cascade	Biological process	17848177
SESN2	83667	sestrin 2	mitochondrial DNA metabolic process	Biological process	-
ARFGAP1	55738	ADP-ribosylation factor GTPase activating protein 1	endoplasmic reticulum unfolded protein response	Biological process	-
MAP2K5	5607	mitogen-activated protein kinase kinase 5	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	Biological process	20551324
ADAM23	8745	ADAM metallopeptidase domain 23	cell adhesion	Biological process	-
ZWINT	11130	ZW10 interacting kinetochore protein	nucleus	Cellular component	-
SRGN	5552	serglycin	mast cell secretory granule organization	Biological process	-
OR10S1	219873	olfactory receptor, family 10, subfamily S, member 1	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
PDK1	5163	pyruvate dehydrogenase kinase, isozyme 1	mitochondrial matrix	Cellular component	-
B3GALT6	126792	UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6	glycosaminoglycan metabolic process	Biological process	-
ABCB1	5243	ATP-binding cassette, sub-family B (MDR/TAP), member 1	integral component of membrane	Cellular component	-
SLC6A20	54716	solute carrier family 6 (proline IMINO transporter), member 20	proline transport	Biological process	19033659
TLR8	51311	toll-like receptor 8	cellular response to mechanical stimulus	Biological process	19593445
CTSH	1512	cathepsin H	immune response-regulating signaling pathway	Biological process	16822283
ENG	2022	endoglin	transforming growth factor beta receptor homodimeric complex	Cellular component	1326540
PLEKHA5	54477	pleckstrin homology domain containing, family A member 5	membrane	Cellular component	19946888
ARPP19	10776	cAMP-regulated phosphoprotein, 19kDa	regulation of protein phosphatase type 2A activity	Biological process	-
DEFA1	1667	defensin, alpha 1	extracellular region	Cellular component	-
HNRNPM	4670	heterogeneous nuclear ribonucleoprotein M	extracellular matrix	Cellular component	23658023
MLYCD	23417	malonyl-CoA decarboxylase	regulation of glucose metabolic process	Biological process	18314420
UNC13C	440279	unc-13 homolog C (C. elegans)	synaptic transmission	Biological process	-
TRAF2	7186	TNF receptor-associated factor 2	cellular protein complex assembly	Biological process	-
MCTS1	28985	malignant T cell amplified sequence 1	cellular response to DNA damage stimulus	Biological process	-
CAPN10	11132	calpain 10	cytoskeletal protein binding	Molecular function	-
PSEN1	5663	presenilin 1	embryonic limb morphogenesis	Biological process	-
CLN8	2055	ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)	protein catabolic process	Biological process	10740217
APOBEC1	339	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	cytidine to uridine editing	Biological process	-
STAG2	10735	stromal antigen 2	actin cytoskeleton	Cellular component	-
MT1X	4501	metallothionein 1X	cellular response to cadmium ion	Biological process	16827180
TOPORS	10210	topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase	ciliary basal body	Cellular component	21159800
GTF3C6	112495	general transcription factor IIIC, polypeptide 6, alpha 35kDa	transcription factor TFIIIC complex	Cellular component	17409385
CBFA2T3	863	core-binding factor, runt domain, alpha subunit 2; translocated to, 3	protein binding	Molecular function	16966434
RAB7A	7879	RAB7A, member RAS oncogene family	extracellular exosome	Cellular component	19056867
GJA1	2697	gap junction protein, alpha 1, 43kDa	in utero embryonic development	Biological process	-
PEBP1	5037	phosphatidylethanolamine binding protein 1	negative regulation of endopeptidase activity	Biological process	-
ALDH9A1	223	aldehyde dehydrogenase 9 family, member A1	protein homodimerization activity	Molecular function	-
YKT6	10652	YKT6 v-SNARE homolog (S. cerevisiae)	cytoplasmic vesicle membrane	Cellular component	-
WEE1	7465	WEE1 G2 checkpoint kinase	protein tyrosine kinase activity	Molecular function	7774574
SH2B2	10603	SH2B adaptor protein 2	plasma membrane	Cellular component	9989826
HCN4	10021	hyperpolarization activated cyclic nucleotide gated potassium channel 4	cation transport	Biological process	12750403
BRAF	673	B-Raf proto-oncogene, serine/threonine kinase	positive regulation of peptidyl-serine phosphorylation	Biological process	19667065
RPS6	6194	ribosomal protein S6	activation-induced cell death of T cells	Biological process	-
TC2N	123036	tandem C2 domains, nuclear	calcium ion-dependent exocytosis of neurotransmitter	Biological process	-
DNAJB13	374407	DnaJ (Hsp40) homolog, subfamily B, member 13	cellular_component	Cellular component	-
ERVK-25	100862683	endogenous retrovirus group K, member 25	plasma membrane	Cellular component	-
ACO1	48	aconitase 1, soluble	cytoplasm	Cellular component	1738601
DZIP1L	199221	DAZ interacting zinc finger protein 1-like	protein binding	Molecular function	25416956
CFL1	1072	cofilin 1 (non-muscle)	negative regulation of apoptotic process	Biological process	16130169
STAU1	6780	staufen double-stranded RNA binding protein 1	cell body	Cellular component	15121898
DMRTC1B	728656	DMRT-like family C1B	sex differentiation	Biological process	-
CUL9	23113	cullin 9	protein ubiquitination	Biological process	24793696
RAB34	83871	RAB34, member RAS oncogene family	vesicle	Cellular component	17881736
HAX1	10456	HCLS1 associated protein X-1	protein N-terminus binding	Molecular function	11554782
PID1	55022	phosphotyrosine interaction domain containing 1	protein binding	Molecular function	25416956
MAPK8	5599	mitogen-activated protein kinase 8	negative regulation of apoptotic process	Biological process	14967141
YIPF3	25844	Yip1 domain family, member 3	nucleoplasm	Cellular component	-
CXCL8	3576	chemokine (C-X-C motif) ligand 8	receptor internalization	Biological process	10734056
ZNF705G	100131980	zinc finger protein 705G	metal ion binding	Molecular function	-
NOS1	4842	nitric oxide synthase 1 (neuronal)	negative regulation of hydrolase activity	Biological process	-
IGLC6	3542	immunoglobulin lambda constant 6 (Kern+Oz- marker, gene/pseudogene)	regulation of immune response	Biological process	-
ATP1A4	480	ATPase, Na+/K+ transporting, alpha 4 polypeptide	ion transmembrane transport	Biological process	-
WNT16	51384	wingless-type MMTV integration site family, member 16	frizzled binding	Molecular function	-
UPF1	5976	UPF1 regulator of nonsense transcripts homolog (yeast)	nucleoplasm	Cellular component	-
TMPRSS11A	339967	transmembrane protease, serine 11A	proteolysis	Biological process	-
MAPK4	5596	mitogen-activated protein kinase 4	protein kinase binding	Molecular function	-
GUCA1C	9626	guanylate cyclase activator 1C	calcium sensitive guanylate cyclase activator activity	Molecular function	10037746
PPP1R2	5504	protein phosphatase 1, regulatory (inhibitor) subunit 2	regulation of signal transduction	Biological process	-
LIM2	3982	lens intrinsic membrane protein 2, 19kDa	cell junction	Cellular component	2584203
UBB	7314	ubiquitin B	viral life cycle	Biological process	-
Sep-11	55752	septin 11	GTP binding	Molecular function	-
NR1H3	10062	nuclear receptor subfamily 1, group H, member 3	negative regulation of interferon-gamma-mediated signaling pathway	Biological process	21268089
VPS11	55823	vacuolar protein sorting 11 homolog (S. cerevisiae)	early endosome	Cellular component	21148287
RALB	5899	v-ral simian leukemia viral oncogene homolog B	cellular response to starvation	Biological process	24056301
SERP1	27230	stress-associated endoplasmic reticulum protein 1	protein glycosylation	Biological process	-
CENPV	201161	centromere protein V	centromere complex assembly	Biological process	18772885
IFNG	3458	interferon, gamma	movement of cell or subcellular component	Biological process	10477596
ITGB8	3696	integrin, beta 8	placenta blood vessel development	Biological process	19267251
HSP90AB4P	664618	heat shock protein 90kDa alpha (cytosolic), class B member 4, pseudogene	unfolded protein binding	Molecular function	-
PACSIN1	29993	protein kinase C and casein kinase substrate in neurons 1	phospholipid binding	Molecular function	19549836
ANGPT2	285	angiopoietin 2	receptor binding	Molecular function	10766762
RIPPLY1	92129	ripply transcriptional repressor 1	somite specification	Biological process	-
TP53BP2	7159	tumor protein p53 binding protein 2	identical protein binding	Molecular function	18448430
TRAF2	7186	TNF receptor-associated factor 2	negative regulation of neuron death	Biological process	18221368
TEK	7010	TEK tyrosine kinase, endothelial	heart development	Biological process	-
NDUFS2	4720	NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)	metal ion binding	Molecular function	-
MTTP	4547	microsomal triglyceride transfer protein	lipid binding	Molecular function	-
CCL3	6348	chemokine (C-C motif) ligand 3	cytoskeleton organization	Biological process	10072545
CER1	9350	cerberus 1, DAN family BMP antagonist	negative regulation of BMP signaling pathway	Biological process	10049596
SALL1	6299	spalt-like transcription factor 1	positive regulation of transcription, DNA-templated	Biological process	15158448
PLEKHF1	79156	pleckstrin homology domain containing, family F (with FYVE domain) member 1	endosome	Cellular component	22115783
HIST1H4E	8367	histone cluster 1, H4e	telomere maintenance	Biological process	-
SETDB1	9869	SET domain, bifurcated 1	DNA binding	Molecular function	-
HLA-DPA1	3113	major histocompatibility complex, class II, DP alpha 1	positive regulation of T cell proliferation	Biological process	20356827
AQP11	282679	aquaporin 11	urea transport	Biological process	16650285
OTUB2	78990	OTU deubiquitinase, ubiquitin aldehyde binding 2	protein binding	Molecular function	25416956
GPX1	2876	glutathione peroxidase 1	regulation of neuron apoptotic process	Biological process	-
LMBRD1	55788	LMBR1 domain containing 1	membrane	Cellular component	19946888
PRAMEF22	653606	PRAME family member 22	retinoic acid receptor binding	Molecular function	-
RPLP2	6181	ribosomal protein, large, P2	translational initiation	Biological process	-
NDUFS6	4726	NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)	respiratory electron transport chain	Biological process	-
CIRBP	1153	cold inducible RNA binding protein	negative regulation of translation	Biological process	-
OXSM	54995	3-oxoacyl-ACP synthase, mitochondrial	cytoplasm	Cellular component	-
FGB	2244	fibrinogen beta chain	structural molecule activity	Molecular function	8910396
MRGPRG	386746	MAS-related GPR, member G	G-protein coupled receptor activity	Molecular function	-
PCSK9	255738	proprotein convertase subtilisin/kexin type 9	triglyceride metabolic process	Biological process	-
KIF11	3832	kinesin family member 11	cytosol	Cellular component	-
NTRK1	4914	neurotrophic tyrosine kinase, receptor, type 1	protein complex	Cellular component	-
OGT	8473	O-linked N-acetylglucosamine (GlcNAc) transferase	microtubule organizing center	Cellular component	-
EIF3M	10480	eukaryotic translation initiation factor 3, subunit M	regulation of translational initiation	Biological process	-
APC	324	adenomatous polyposis coli	positive regulation of protein catabolic process	Biological process	12952940
POU5F1	5460	POU class 5 homeobox 1	positive regulation of catenin import into nucleus	Biological process	19736317
IL6	3569	interleukin 6	cytokine activity	Molecular function	10443688
CHD8	57680	chromodomain helicase DNA binding protein 8	transcription, DNA-templated	Biological process	-
GLRA1	2741	glycine receptor, alpha 1	intracellular membrane-bounded organelle	Cellular component	7506679
FES	2242	FES proto-oncogene, tyrosine kinase	regulation of cell adhesion	Biological process	11509660
GLCE	26035	glucuronic acid epimerase	heparin biosynthetic process	Biological process	-
IKBKB	3551	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	positive regulation of sodium ion transport	Biological process	-
DSCR3	10311	Down syndrome critical region 3	nucleus	Cellular component	16780588
BMPR2	659	bone morphogenetic protein receptor, type II (serine/threonine kinase)	caveola	Cellular component	15657086
E2F2	1870	E2F transcription factor 2	DNA binding	Molecular function	8246995
CTSS	1520	cathepsin S	collagen catabolic process	Biological process	22952693
AGGF1	55109	angiogenic factor with G patch and FHA domains 1	nucleic acid binding	Molecular function	-
BTG2	7832	BTG family, member 2	negative regulation of cell proliferation	Biological process	23236473
IL2	3558	interleukin 2	T cell differentiation	Biological process	8476561
COX17	10063	COX17 cytochrome c oxidase copper chaperone	protein binding	Molecular function	16189514
PRUNE	58497	prune exopolyphosphatase	focal adhesion	Cellular component	-
MAPRE3	22924	microtubule-associated protein, RP/EB family, member 3	perinuclear region of cytoplasm	Cellular component	10644998
TARS	6897	threonyl-tRNA synthetase	cytosol	Cellular component	-
RNF34	80196	ring finger protein 34, E3 ubiquitin protein ligase	phosphatidylinositol phosphate binding	Molecular function	15069192
BTN3A3	10384	butyrophilin, subfamily 3, member A3	Golgi apparatus	Cellular component	-
MAP2K4	6416	mitogen-activated protein kinase kinase 4	cellular response to mechanical stimulus	Biological process	19593445
CCR4	1233	chemokine (C-C motif) receptor 4	neuron migration	Biological process	-
HMGB1	3146	high mobility group box 1	apoptotic process	Biological process	-
NR2E1	7101	nuclear receptor subfamily 2, group E, member 1	retina development in camera-type eye	Biological process	-
CDH11	1009	cadherin 11, type 2, OB-cadherin (osteoblast)	cell junction assembly	Biological process	-
PAK2	5062	p21 protein (Cdc42/Rac)-activated kinase 2	vascular endothelial growth factor receptor signaling pathway	Biological process	-
DBNL	28988	drebrin-like	protein domain specific binding	Molecular function	-
MAPK7	5598	mitogen-activated protein kinase 7	neurotrophin TRK receptor signaling pathway	Biological process	-
AMER2	219287	APC membrane recruitment protein 2	Wnt signaling pathway	Biological process	-
SLC4A1	6521	solute carrier family 4 (anion exchanger), member 1 (Diego blood group)	transmembrane transport	Biological process	-
RABGEF1	27342	RAB guanine nucleotide exchange factor (GEF) 1	protein binding	Molecular function	16189514
STAT1	6772	signal transducer and activator of transcription 1, 91kDa	identical protein binding	Molecular function	8605877
NR5A1	2516	nuclear receptor subfamily 5, group A, member 1	nucleoplasm	Cellular component	-
CDX2	1045	caudal type homeobox 2	sequence-specific DNA binding transcription factor activity	Molecular function	9459001
NKX2-2	4821	NK2 homeobox 2	chromatin binding	Molecular function	-
HIST1H4E	8367	histone cluster 1, H4e	protein complex	Cellular component	14718166
AGT	183	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	superoxide-generating NADPH oxidase activator activity	Molecular function	19193863
ARGLU1	55082	arginine and glutamate rich 1	regulation of transcription, DNA-templated	Biological process	-
CDC42SE1	56882	CDC42 small effector 1	negative regulation of GTPase activity	Biological process	10816584
DHX33	56919	DEAH (Asp-Glu-Ala-His) box polypeptide 33	ATP binding	Molecular function	-
MAPT	4137	microtubule-associated protein tau	apolipoprotein binding	Molecular function	7566652
EPS8	2059	epidermal growth factor receptor pathway substrate 8	N-methyl-D-aspartate selective glutamate receptor complex	Cellular component	-
DLG1	1739	discs, large homolog 1 (Drosophila)	lateral plasma membrane	Cellular component	-
PDE4D	5144	phosphodiesterase 4D, cAMP-specific	cAMP catabolic process	Biological process	19252089
RHOB	388	ras homolog family member B	negative regulation of cell cycle	Biological process	-
TAF6	6878	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa	regulation of transcription, DNA-templated	Biological process	15328371
MAP3K5	4217	mitogen-activated protein kinase kinase kinase 5	JNK cascade	Biological process	21771788
TWF2	11344	twinfilin actin-binding protein 2	cell projection organization	Biological process	-
ANKHD1	54882	ankyrin repeat and KH domain containing 1	protein binding	Molecular function	12812986
CRAT	1384	carnitine O-acetyltransferase	carnitine metabolic process, CoA-linked	Biological process	15099582
RAC1	5879	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	blood coagulation	Biological process	-
ELF5	2001	E74-like factor 5 (ets domain transcription factor)	cell proliferation	Biological process	9840936
PCCB	5096	propionyl CoA carboxylase, beta polypeptide	small molecule metabolic process	Biological process	-
RAB11FIP2	22841	RAB11 family interacting protein 2 (class I)	cytoplasm	Cellular component	-
ADRB1	153	adrenoceptor beta 1	regulation of inhibitory postsynaptic membrane potential	Biological process	-
MARK4	57787	MAP/microtubule affinity-regulating kinase 4	protein serine/threonine kinase activity	Molecular function	15009667
WT1	7490	Wilms tumor 1	negative regulation of metanephric glomerular mesangial cell proliferation	Biological process	-
FCGR1B	2210	Fc fragment of IgG, high affinity Ib, receptor (CD64)	plasma membrane	Cellular component	-
BLMH	642	bleomycin hydrolase	cysteine-type endopeptidase activity	Molecular function	-
LOX	4015	lysyl oxidase	extracellular matrix organization	Biological process	-
PELI2	57161	pellino E3 ubiquitin protein ligase family member 2	protein binding	Molecular function	12860405
LNPEP	4012	leucyl/cystinyl aminopeptidase	membrane organization	Biological process	-
NR1H3	10062	nuclear receptor subfamily 1, group H, member 3	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
CAAP1	79886	caspase activity and apoptosis inhibitor 1	apoptotic process	Biological process	-
CYP4X1	260293	cytochrome P450, family 4, subfamily X, polypeptide 1	aromatase activity	Molecular function	-
PRSS1	5644	protease, serine, 1 (trypsin 1)	vitamin metabolic process	Biological process	-
SETSIP	646817	SET-like protein	positive regulation of transcription from RNA polymerase II promoter	Biological process	22869753
EIF5A	1984	eukaryotic translation initiation factor 5A	cytosol	Cellular component	-
SALL3	27164	spalt-like transcription factor 3	nucleus	Cellular component	-
MYH7	4625	myosin, heavy chain 7, cardiac muscle, beta	myosin filament	Cellular component	19336582
LYN	4067	LYN proto-oncogene, Src family tyrosine kinase	stimulatory C-type lectin receptor signaling pathway	Biological process	-
ITGB1BP1	9270	integrin beta 1 binding protein 1	positive regulation of cell division	Biological process	-
CATSPERD	257062	catsper channel auxiliary subunit delta	protein binding	Molecular function	25416956
BMP2	650	bone morphogenetic protein 2	protein heterodimerization activity	Molecular function	7811286
MAP2K2	5605	mitogen-activated protein kinase kinase 2	Fc-epsilon receptor signaling pathway	Biological process	-
GATA1	2623	GATA binding protein 1 (globin transcription factor 1)	DNA binding, bending	Molecular function	-
GATA3	2625	GATA binding protein 3	nephric duct formation	Biological process	-
PKD1	5310	polycystic kidney disease 1 (autosomal dominant)	polycystin complex	Cellular component	-
INAFM1	255783	InaF-motif containing 1	integral component of membrane	Cellular component	-
CYP3A5	1577	cytochrome P450, family 3, subfamily A, polypeptide 5	aromatase activity	Molecular function	-
AP3M1	26985	adaptor-related protein complex 3, mu 1 subunit	protein targeting to lysosome	Biological process	10024875
CASP4	837	caspase 4, apoptosis-related cysteine peptidase	regulation of apoptotic process	Biological process	-
CD24	100133941	CD24 molecule	positive regulation of MAP kinase activity	Biological process	12496407
MCL1	4170	myeloid cell leukemia 1	apoptotic mitochondrial changes	Biological process	-
APOC3	345	apolipoprotein C-III	extracellular exosome	Cellular component	23376485
COMT	1312	catechol-O-methyltransferase	plasma membrane	Cellular component	-
L1CAM	3897	L1 cell adhesion molecule	focal adhesion	Cellular component	21423176
RPLP1	6176	ribosomal protein, large, P1	translational elongation	Biological process	-
TFEC	22797	transcription factor EC	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	-
CTBS	1486	chitobiase, di-N-acetyl-	chitin binding	Molecular function	-
NMUR1	10316	neuromedin U receptor 1	intracellular	Cellular component	10899166
ZNF283	284349	zinc finger protein 283	transcription, DNA-templated	Biological process	-
HCFC1	3054	host cell factor C1	histone H4-K5 acetylation	Biological process	20018852
ALOX12	239	arachidonate 12-lipoxygenase	fatty acid oxidation	Biological process	15111312
ELANE	1991	elastase, neutrophil expressed	negative regulation of growth of symbiont in host	Biological process	-
ARRB1	408	arrestin, beta 1	cytoplasmic vesicle membrane	Cellular component	-
NRP1	8829	neuropilin 1	positive regulation of axon extension involved in axon guidance	Biological process	-
UNC13A	23025	unc-13 homolog A (C. elegans)	synaptic transmission, glutamatergic	Biological process	-
AZU1	566	azurocidin 1	positive regulation of MHC class II biosynthetic process	Biological process	12465046
MYBPH	4608	myosin binding protein H	regulation of striated muscle contraction	Biological process	8486381
TNFAIP3	7128	tumor necrosis factor, alpha-induced protein 3	ligase activity	Molecular function	-
PEX5	5830	peroxisomal biogenesis factor 5	protein N-terminus binding	Molecular function	19197237
TNFRSF14	8764	tumor necrosis factor receptor superfamily, member 14	defense response to Gram-positive bacterium	Biological process	-
BRPF1	7862	bromodomain and PHD finger containing, 1	nucleoplasm	Cellular component	-
DOCK4	9732	dedicator of cytokinesis 4	membrane	Cellular component	20679435
INTS10	55174	integrator complex subunit 10	snRNA processing	Biological process	16239144
TNFAIP3	7128	tumor necrosis factor, alpha-induced protein 3	B-1 B cell homeostasis	Biological process	-
DBNL	28988	drebrin-like	protein binding	Molecular function	16189514
GPER1	2852	G protein-coupled estrogen receptor 1	cytosol	Cellular component	-
ZBED4	9889	zinc finger, BED-type containing 4	nucleoplasm	Cellular component	-
MYC	4609	v-myc avian myelocytomatosis viral oncogene homolog	cellular iron ion homeostasis	Biological process	9924025
ITGA8	8516	integrin, alpha 8	perikaryon	Cellular component	-
DAB2	1601	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)	extracellular exosome	Cellular component	23376485
ADAR	103	adenosine deaminase, RNA-specific	innate immune response	Biological process	16475990
STAT1	6772	signal transducer and activator of transcription 1, 91kDa	RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity	Molecular function	21268089
LARP4B	23185	La ribonucleoprotein domain family, member 4B	nucleolus	Cellular component	-
LPGAT1	9926	lysophosphatidylglycerol acyltransferase 1	glycerophospholipid biosynthetic process	Biological process	-
SKI	6497	SKI proto-oncogene	transcription factor complex	Cellular component	-
GNB4	59345	guanine nucleotide binding protein (G protein), beta polypeptide 4	plasma membrane	Cellular component	-
CASP9	842	caspase 9, apoptosis-related cysteine peptidase	neurotrophin TRK receptor signaling pathway	Biological process	-
MORC3	23515	MORC family CW-type zinc finger 3	protein stabilization	Biological process	17332504
OPTN	10133	optineurin	defense response to Gram-negative bacterium	Biological process	21617041
FRS2	10818	fibroblast growth factor receptor substrate 2	regulation of apoptotic process	Biological process	-
LRRCC1	85444	leucine rich repeat and coiled-coil centrosomal protein 1	centrosome	Cellular component	21399614
SNRPD3	6634	small nuclear ribonucleoprotein D3 polypeptide 18kDa	protein binding	Molecular function	11714716
VPS4B	9525	vacuolar protein sorting 4 homolog B (S. cerevisiae)	cytoplasmic microtubule organization	Biological process	-
SPATA31A1	647060	SPATA31 subfamily A, member 1	spermatogenesis	Biological process	-
CCDC155	147872	coiled-coil domain containing 155	spermatogenesis	Biological process	-
MKNK2	2872	MAP kinase interacting serine/threonine kinase 2	protein binding	Molecular function	20936779
NEU4	129807	sialidase 4	post-translational protein modification	Biological process	-
SLC35D1	23169	solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1	endoplasmic reticulum membrane	Cellular component	-
COL3A1	1281	collagen, type III, alpha 1	endoplasmic reticulum lumen	Cellular component	-
UGT1A1	54658	UDP glucuronosyltransferase 1 family, polypeptide A1	negative regulation of catalytic activity	Biological process	19996319
VGF	7425	VGF nerve growth factor inducible	response to cold	Biological process	-
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	regulation of calcium ion import	Biological process	19996314
PDX1	3651	pancreatic and duodenal homeobox 1	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity	Molecular function	-
GTF2A1	2957	general transcription factor IIA, 1, 19/37kDa	cytoplasm	Cellular component	-
MRPL4	51073	mitochondrial ribosomal protein L4	mitochondrial translational termination	Biological process	-
KRT71	112802	keratin 71, type II	hair follicle morphogenesis	Biological process	22592156
LHX1	3975	LIM homeobox 1	branching involved in ureteric bud morphogenesis	Biological process	-
SPINK5	11005	serine peptidase inhibitor, Kazal type 5	serine-type endopeptidase inhibitor activity	Molecular function	10419450
ERAP1	51752	endoplasmic reticulum aminopeptidase 1	regulation of blood pressure	Biological process	15691326
ILK	3611	integrin-linked kinase	nucleoplasm	Cellular component	-
STRIP2	57464	striatin interacting protein 2	molecular_function	Molecular function	-
HOXD8	3234	homeobox D8	nucleus	Cellular component	2568311
LIPH	200879	lipase, member H	heparin binding	Molecular function	12963729
SLC6A3	6531	solute carrier family 6 (neurotransmitter transporter), member 3	monoamine transport	Biological process	16024787
CRY1	1407	cryptochrome circadian clock 1	negative regulation of circadian rhythm	Biological process	-
CACNA1D	776	calcium channel, voltage-dependent, L type, alpha 1D subunit	metal ion binding	Molecular function	-
PTPRO	5800	protein tyrosine phosphatase, receptor type, O	protein dephosphorylation	Biological process	10498613
DHRS4	10901	dehydrogenase/reductase (SDR family) member 4	peroxisome	Cellular component	17230527
SNX3	8724	sorting nexin 3	regulation of cellular protein metabolic process	Biological process	-
RPL21	6144	ribosomal protein L21	cytosolic large ribosomal subunit	Cellular component	12962325
FPR1	2357	formyl peptide receptor 1	nitric oxide mediated signal transduction	Biological process	10861041
AURKA	6790	aurora kinase A	histone serine kinase activity	Molecular function	-
ZNF695	57116	zinc finger protein 695	nucleus	Cellular component	-
PSMD1	5707	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	G1/S transition of mitotic cell cycle	Biological process	-
SLC30A2	7780	solute carrier family 30 (zinc transporter), member 2	late endosome	Cellular component	17349999
PID1	55022	phosphotyrosine interaction domain containing 1	positive regulation of ATP biosynthetic process	Biological process	-
LGALS1	3956	lectin, galactoside-binding, soluble, 1	response to axon injury	Biological process	-
MTF2	22823	metal response element binding transcription factor 2	positive regulation of histone H3-K27 methylation	Biological process	-
TCF7L2	6934	transcription factor 7-like 2 (T-cell specific, HMG-box)	regulation of oligodendrocyte differentiation	Biological process	-
PSMD7	5713	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	Biological process	-
MAPK1	5594	mitogen-activated protein kinase 1	cytoskeleton	Cellular component	19565474
FOXR1	283150	forkhead box R1	protein binding	Molecular function	25416956
ZCCHC7	84186	zinc finger, CCHC domain containing 7	nucleolus	Cellular component	-
HSPG2	3339	heparan sulfate proteoglycan 2	extracellular matrix organization	Biological process	-
CTXN3	613212	cortexin 3	integral component of membrane	Cellular component	-
RNF10	9921	ring finger protein 10	zinc ion binding	Molecular function	-
MGMT	4255	O-6-methylguanine-DNA methyltransferase	membrane	Cellular component	19946888
MYH7	4625	myosin, heavy chain 7, cardiac muscle, beta	regulation of heart rate	Biological process	15621050
CYP2E1	1571	cytochrome P450, family 2, subfamily E, polypeptide 1	small molecule metabolic process	Biological process	-
PCSK9	255738	proprotein convertase subtilisin/kexin type 9	rough endoplasmic reticulum	Cellular component	-
CRH	1392	corticotropin releasing hormone	hormone activity	Molecular function	7585095
RTN4RL1	146760	reticulon 4 receptor-like 1	external side of plasma membrane	Cellular component	-
UEVLD	55293	UEV and lactate/malate dehyrogenase domains	oxidation-reduction process	Biological process	-
GCNT6	644378	glucosaminyl (N-acetyl) transferase 6	integral component of membrane	Cellular component	-
IGLL1	3543	immunoglobulin lambda-like polypeptide 1	extracellular exosome	Cellular component	23376485
ID4	3400	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	RNA polymerase II transcription factor binding	Molecular function	-
MYO9B	4650	myosin IXB	calmodulin binding	Molecular function	16338935
FIP1L1	81608	factor interacting with PAPOLA and CPSF1	mRNA processing	Biological process	-
LYN	4067	LYN proto-oncogene, Src family tyrosine kinase	cellular response to peptide hormone stimulus	Biological process	-
EDNRA	1909	endothelin receptor type A	positive regulation of inflammatory response	Biological process	-
LEMD3	23592	LEM domain containing 3	blood vessel endothelial cell migration involved in intussusceptive angiogenesis	Biological process	-
MEN1	4221	multiple endocrine neoplasia I	nucleoplasm	Cellular component	-
SPATA13	221178	spermatogenesis associated 13	Rac guanyl-nucleotide exchange factor activity	Molecular function	17599059
ACVR1C	130399	activin A receptor, type IC	protein phosphorylation	Biological process	12063393
SKP1	6500	S-phase kinase-associated protein 1	circadian rhythm	Biological process	-
OGG1	4968	8-oxoguanine DNA glycosylase	aging	Biological process	-
CXCL8	3576	chemokine (C-X-C motif) ligand 8	positive regulation of angiogenesis	Biological process	19035451
GRB2	2885	growth factor receptor-bound protein 2	positive regulation of signal transduction	Biological process	-
OXSR1	9943	oxidative stress responsive 1	negative regulation of potassium ion transmembrane transporter activity	Biological process	-
CTDP1	9150	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1	cytoplasm	Cellular component	-
ABL2	27	ABL proto-oncogene 2, non-receptor tyrosine kinase	cerebellum morphogenesis	Biological process	-
SI	6476	sucrase-isomaltase (alpha-glucosidase)	extracellular exosome	Cellular component	23533145
PSD3	23362	pleckstrin and Sec7 domain containing 3	cell junction	Cellular component	-
SLC26A3	1811	solute carrier family 26 (anion exchanger), member 3	ion transport	Biological process	-
SCGB1A1	7356	secretoglobin, family 1A, member 1 (uteroglobin)	negative regulation of catalytic activity	Biological process	-
PRKCZ	5590	protein kinase C, zeta	insulin receptor substrate binding	Molecular function	15069075
CSNK1D	1453	casein kinase 1, delta	DNA repair	Biological process	8786104
TXLNA	200081	taxilin alpha	exocytosis	Biological process	-
SOX11	6664	SRY (sex determining region Y)-box 11	noradrenergic neuron differentiation	Biological process	-
TGM1	7051	transglutaminase 1	extracellular exosome	Cellular component	19199708
VAMP8	8673	vesicle-associated membrane protein 8	plasma membrane	Cellular component	-
EPHB2	2048	EPH receptor B2	ephrin receptor signaling pathway	Biological process	-
CWC27	10283	CWC27 spliceosome-associated protein homolog (S. cerevisiae)	catalytic step 2 spliceosome	Cellular component	11991638
STK17A	9263	serine/threonine kinase 17a	positive regulation of apoptotic process	Biological process	21489989
CEMIP	57214	cell migration inducing protein, hyaluronan binding	cytoplasm	Cellular component	14577002
ADA	100	adenosine deaminase	purine ribonucleoside monophosphate biosynthetic process	Biological process	-
RAMP3	10268	receptor (G protein-coupled) activity modifying protein 3	lysosome	Cellular component	15613468
EHD2	30846	EH-domain containing 2	nucleic acid binding	Molecular function	10673336
TIE1	7075	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	vasculogenesis	Biological process	-
SFTPA1	653509	surfactant protein A1	collagen trimer	Cellular component	-
OR5AU1	390445	olfactory receptor, family 5, subfamily AU, member 1	integral component of plasma membrane	Cellular component	-
AGO4	192670	argonaute RISC catalytic component 4	epidermal growth factor receptor signaling pathway	Biological process	-
EIF1AX	1964	eukaryotic translation initiation factor 1A, X-linked	translation factor activity, RNA binding	Molecular function	8106356
PIP	5304	prolactin-induced protein	extracellular region	Cellular component	-
HPSE	10855	heparanase	lysosomal membrane	Cellular component	-
PIWIL4	143689	piwi-like RNA-mediated gene silencing 4	meiotic cell cycle	Biological process	-
MRPS18B	28973	mitochondrial ribosomal protein S18B	mitochondrial translation	Biological process	-
SEL1L2	80343	sel-1 suppressor of lin-12-like 2 (C. elegans)	integral component of membrane	Cellular component	-
SLC6A4	6532	solute carrier family 6 (neurotransmitter transporter), member 4	cellular response to cGMP	Biological process	-
GGT7	2686	gamma-glutamyltransferase 7	proteolysis	Biological process	-
COX8A	1351	cytochrome c oxidase subunit VIIIA (ubiquitous)	activation of mitophagy in response to mitochondrial depolarization	Biological process	22020285
SIGLEC15	284266	sialic acid binding Ig-like lectin 15	protein complex	Cellular component	-
NDUFS7	374291	NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)	protein binding	Molecular function	15186778
CSTF2	1478	cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa	protein binding	Molecular function	10477523
GYG1	2992	glycogenin 1	protein binding	Molecular function	16189514
ZNF225	7768	zinc finger protein 225	nucleus	Cellular component	-
SLC35A3	23443	solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3	Golgi membrane	Cellular component	-
TRIM26	7726	tripartite motif containing 26	cytosol	Cellular component	-
PARP10	84875	poly (ADP-ribose) polymerase family, member 10	negative regulation of protein K63-linked ubiquitination	Biological process	23575687
PSMD10	5716	proteasome (prosome, macropain) 26S subunit, non-ATPase, 10	negative regulation of MAPK cascade	Biological process	19729910
SLC34A3	142680	solute carrier family 34 (type II sodium/phosphate cotransporter), member 3	phosphate ion transmembrane transport	Biological process	11880379
HOOK2	29911	hook microtubule-tethering protein 2	lysosome organization	Biological process	18799622
RNF135	84282	ring finger protein 135	cytoplasm	Cellular component	19484123
TRPC1	7220	transient receptor potential cation channel, subfamily C, member 1	axon guidance	Biological process	-
HBS1L	10767	HBS1-like translational GTPase	signal transduction	Biological process	9872408
TSFM	10102	Ts translation elongation factor, mitochondrial	translational elongation	Biological process	7615523
RDM1	201299	RAD52 motif containing 1	DNA recombination	Biological process	-
RPS20	6224	ribosomal protein S20	viral transcription	Biological process	-
PRMT1	3276	protein arginine methyltransferase 1	regulation of transcription, DNA-templated	Biological process	-
PIN4	5303	peptidylprolyl cis/trans isomerase, NIMA-interacting 4	mitochondrial matrix	Cellular component	-
DMD	1756	dystrophin	syntrophin complex	Cellular component	21164104
BFSP2	8419	beaded filament structural protein 2, phakinin	structural constituent of cytoskeleton	Molecular function	9628810
TAOK2	9344	TAO kinase 2	positive regulation of stress-activated MAPK cascade	Biological process	17396146
AJUBA	84962	ajuba LIM protein	cytoplasmic mRNA processing body	Cellular component	20616046
CBX4	8535	chromobox homolog 4	SUMO transferase activity	Molecular function	-
NIM1K	167359	NIM1 serine/threonine protein kinase	magnesium ion binding	Molecular function	15733851
SMURF2	64750	SMAD specific E3 ubiquitin protein ligase 2	protein binding	Molecular function	14755250
OR10J1	26476	olfactory receptor, family 10, subfamily J, member 1	odorant binding	Molecular function	-
KIRREL2	84063	kin of IRRE like 2 (Drosophila)	cell adhesion	Biological process	12837264
EXOSC6	118460	exosome component 6	rRNA 3'-end processing	Biological process	-
OSR2	116039	odd-skipped related transciption factor 2	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
USH2A	7399	Usher syndrome 2A (autosomal recessive, mild)	stereocilium bundle	Cellular component	-
PTH1R	5745	parathyroid hormone 1 receptor	bone mineralization	Biological process	-
TMEM41B	440026	transmembrane protein 41B	integral component of membrane	Cellular component	-
PITX2	5308	paired-like homeodomain 2	RNA polymerase II transcription coactivator activity	Molecular function	9685346
TRPT1	83707	tRNA phosphotransferase 1	tRNA 2'-phosphotransferase activity	Molecular function	-
CDK7	1022	cyclin-dependent kinase 7	protein binding	Molecular function	23397142
TCF19	6941	transcription factor 19	nucleus	Cellular component	-
DPCD	25911	deleted in primary ciliary dyskinesia homolog (mouse)	third ventricle development	Biological process	-
ST6GALNAC4	27090	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4	sialyltransferase activity	Molecular function	10207017
VILL	50853	villin-like	structural constituent of cytoskeleton	Molecular function	9179494
CEP162	22832	centrosomal protein 162kDa	cilium assembly	Biological process	23644468
LMNB2	84823	lamin B2	lamin filament	Cellular component	-
ARID4A	5926	AT rich interactive domain 4A (RBP1-like)	histone H3-K9 trimethylation	Biological process	-
HERC2	8924	HECT and RLD domain containing E3 ubiquitin protein ligase 2	protein ubiquitination	Biological process	20304803
NIFK	84365	nucleolar protein interacting with the FHA domain of MKI67	nucleotide binding	Molecular function	-
ERP29	10961	endoplasmic reticulum protein 29	extracellular exosome	Cellular component	23376485
AGBL3	340351	ATP/GTP binding protein-like 3	proteolysis	Biological process	-
HTR2B	3357	5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled	positive regulation of cytokine production	Biological process	19023134
ADRA2A	150	adrenoceptor alpha 2A	positive regulation of vasodilation	Biological process	-
TNFAIP3	7128	tumor necrosis factor, alpha-induced protein 3	negative regulation of inflammatory response	Biological process	-
CD4	920	CD4 molecule	protein kinase binding	Molecular function	7486703
IKBKAP	8518	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein	regulation of transcription from RNA polymerase II promoter	Biological process	11714725
ANGPT4	51378	angiopoietin 4	leukocyte migration	Biological process	-
KCNJ11	3767	potassium channel, inwardly rectifying subfamily J, member 11	voltage-gated potassium channel complex	Cellular component	20610380
SYNM	23336	synemin, intermediate filament protein	structural constituent of cytoskeleton	Molecular function	11737198
STIL	6491	SCL/TAL1 interrupting locus	multicellular organism growth	Biological process	-
STX10	8677	syntaxin 10	SNARE complex	Cellular component	-
ADGRB3	577	adhesion G protein-coupled receptor B3	plasma membrane	Cellular component	-
MAP4K3	8491	mitogen-activated protein kinase kinase kinase kinase 3	protein phosphorylation	Biological process	9275185
APEX1	328	APEX nuclease (multifunctional DNA repair enzyme) 1	site-specific endodeoxyribonuclease activity, specific for altered base	Molecular function	19188445
LSM5	23658	LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)	RNA binding	Molecular function	-
AR	367	androgen receptor	sequence-specific DNA binding transcription factor activity	Molecular function	11477070
PSMC4	5704	proteasome (prosome, macropain) 26S subunit, ATPase, 4	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	Biological process	-
IDE	3416	insulin-degrading enzyme	negative regulation of proteolysis	Biological process	-
FKBP1A	2280	FK506 binding protein 1A, 12kDa	positive regulation of protein binding	Biological process	18346205
OR10G7	390265	olfactory receptor, family 10, subfamily G, member 7	sensory perception of smell	Biological process	-
CHRM4	1132	cholinergic receptor, muscarinic 4	cell proliferation	Biological process	2739737
RAB25	57111	RAB25, member RAS oncogene family	protein binding	Molecular function	17925226
RSC1A1	6248	regulatory solute carrier protein, family 1, member 1	cell junction	Cellular component	-
SLC35D1	23169	solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1	pyrimidine nucleotide-sugar transmembrane transport	Biological process	-
AAAS	8086	achalasia, adrenocortical insufficiency, alacrimia	cytokine-mediated signaling pathway	Biological process	-
MMRN2	79812	multimerin 2	extracellular exosome	Cellular component	19056867
PFAS	5198	phosphoribosylformylglycinamidine synthase	cytoplasm	Cellular component	-
APITD1	378708	apoptosis-inducing, TAF9-like domain 1	cell division	Biological process	-
ABR	29	active BCR-related	neuromuscular process controlling balance	Biological process	-
FMN2	56776	formin 2	endoplasmic reticulum membrane	Cellular component	-
GNAQ	2776	guanine nucleotide binding protein (G protein), q polypeptide	cytoplasm	Cellular component	9175863
APOA2	336	apolipoprotein A-II	response to glucose	Biological process	14988251
LIG4	3981	ligase IV, DNA, ATP-dependent	positive regulation of fibroblast proliferation	Biological process	-
PRKCE	5581	protein kinase C, epsilon	positive regulation of cytokinesis	Biological process	18604201
AK5	26289	adenylate kinase 5	nucleoside diphosphate kinase activity	Molecular function	23416111
RPS6KA1	6195	ribosomal protein S6 kinase, 90kDa, polypeptide 1	cell cycle	Biological process	-
CDX2	1045	caudal type homeobox 2	transcriptional repressor complex	Cellular component	-
MYH3	4621	myosin, heavy chain 3, skeletal muscle, embryonic	ATPase activity, coupled	Molecular function	16642020
ELP4	26610	elongator acetyltransferase complex subunit 4	Elongator holoenzyme complex	Cellular component	22854966
RAB27B	5874	RAB27B, member RAS oncogene family	trans-Golgi network transport vesicle	Cellular component	19966785
AKT2	208	v-akt murine thymoma viral oncogene homolog 2	protein binding	Molecular function	10490823
CA9	768	carbonic anhydrase IX	plasma membrane	Cellular component	-
RIPK3	11035	receptor-interacting serine-threonine kinase 3	programmed cell death	Biological process	-
TBL1XR1	79718	transducin (beta)-like 1 X-linked receptor 1	nucleus	Cellular component	18193033
CA9	768	carbonic anhydrase IX	microvillus membrane	Cellular component	-
DTX3L	151636	deltex 3 like, E3 ubiquitin ligase	cytoplasm	Cellular component	-
RPL7	6129	ribosomal protein L7	translation	Biological process	-
APLN	8862	apelin	lactation	Biological process	10525157
KRT19	3880	keratin 19, type I	Z disc	Cellular component	-
EME1	146956	essential meiotic structure-specific endonuclease 1	DNA repair	Biological process	-
SNX3	8724	sorting nexin 3	phosphatidylinositol-5-phosphate binding	Molecular function	-
AFTPH	54812	aftiphilin	clathrin binding	Molecular function	15758025
NEK8	284086	NIMA-related kinase 8	protein binding	Molecular function	23418306
EI24	9538	etoposide induced 2.4	autophagy	Biological process	-
CASP3	836	caspase 3, apoptosis-related cysteine peptidase	neurotrophin TRK receptor signaling pathway	Biological process	-
METAP2	10988	methionyl aminopeptidase 2	N-terminal protein amino acid modification	Biological process	8858118
TFDP3	51270	transcription factor Dp family, member 3	DNA binding	Molecular function	-
GCGR	2642	glucagon receptor	hormone-mediated signaling pathway	Biological process	-
VPS37C	55048	vacuolar protein sorting 37 homolog C (S. cerevisiae)	protein binding	Molecular function	23924735
SIGLEC8	27181	sialic acid binding Ig-like lectin 8	carbohydrate binding	Molecular function	-
NOD2	64127	nucleotide-binding oligomerization domain containing 2	regulation of neutrophil chemotaxis	Biological process	-
HIST3H3	8290	histone cluster 3, H3	nucleoplasm	Cellular component	-
ITGB4	3691	integrin, beta 4	cell adhesion	Biological process	2311577
CHD4	1108	chromodomain helicase DNA binding protein 4	ATP-dependent chromatin remodeling	Biological process	16217013
RBBP6	5930	retinoblastoma binding protein 6	microtubule organizing center	Cellular component	-
ABLIM1	3983	actin binding LIM protein 1	stress fiber	Cellular component	22684256
PSMD11	5717	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	apoptotic process	Biological process	-
MAP1S	55201	microtubule-associated protein 1S	perinuclear region of cytoplasm	Cellular component	12762840
DSCR3	10311	Down syndrome critical region 3	protein transporter activity	Molecular function	-
CASP8	841	caspase 8, apoptosis-related cysteine peptidase	viral process	Biological process	-
RBBP9	10741	retinoblastoma binding protein 9	regulation of cell proliferation	Biological process	-
TCEB2	6923	transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)	VCB complex	Cellular component	-
ATP2B1	490	ATPase, Ca++ transporting, plasma membrane 1	integral component of plasma membrane	Cellular component	8396145
TNFRSF21	27242	tumor necrosis factor receptor superfamily, member 21	negative regulation of interleukin-5 secretion	Biological process	-
ZNF354A	6940	zinc finger protein 354A	regulation of transcription from RNA polymerase II promoter	Biological process	9919311
CUL3	8452	cullin 3	cyclin binding	Molecular function	-
CR1	1378	complement component (3b/4b) receptor 1 (Knops blood group)	plasma membrane	Cellular component	-
FGF9	2254	fibroblast growth factor 9	male gonad development	Biological process	17848411
DSCC1	79075	DNA replication and sister chromatid cohesion 1	protein binding	Molecular function	16682347
CXCR2	3579	chemokine (C-X-C motif) receptor 2	dendritic cell chemotaxis	Biological process	16621978
HLA-C	3107	major histocompatibility complex, class I, C	antigen processing and presentation of peptide antigen via MHC class I	Biological process	-
RGS7	6000	regulator of G-protein signaling 7	GTPase activator activity	Molecular function	-
RFXANK	8625	regulatory factor X-associated ankyrin-containing protein	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
CPT2	1376	carnitine palmitoyltransferase 2	fatty acid beta-oxidation	Biological process	-
WFDC8	90199	WAP four-disulfide core domain 8	extracellular region	Cellular component	-
COQ3	51805	coenzyme Q3 methyltransferase	hexaprenyldihydroxybenzoate methyltransferase activity	Molecular function	-
PDCD6	10016	programmed cell death 6	response to calcium ion	Biological process	-
ANAPC4	29945	anaphase promoting complex subunit 4	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
ILF3	3609	interleukin enhancer binding factor 3, 90kDa	nucleoplasm	Cellular component	-
TYR	7299	tyrosinase	cell proliferation	Biological process	-
CBX4	8535	chromobox homolog 4	nucleus	Cellular component	21282530
MIS18A	54069	MIS18 kinetochore protein A	nucleosome assembly	Biological process	-
TEX40	25858	testis expressed 40	cytoplasm	Cellular component	-
IGF1	3479	insulin-like growth factor 1 (somatomedin C)	positive regulation of cell proliferation	Biological process	12746903
CSE1L	1434	CSE1 chromosome segregation 1-like (yeast)	Ran GTPase binding	Molecular function	-
FGR	2268	FGR proto-oncogene, Src family tyrosine kinase	peptidyl-tyrosine autophosphorylation	Biological process	-
PDE3B	5140	phosphodiesterase 3B, cGMP-inhibited	integral component of membrane	Cellular component	-
ZAP70	7535	zeta-chain (TCR) associated protein kinase 70kDa	extrinsic component of cytoplasmic side of plasma membrane	Cellular component	-
PCNA	5111	proliferating cell nuclear antigen	centrosome	Cellular component	18331714
RILPL2	196383	Rab interacting lysosomal protein-like 2	cytoplasm	Cellular component	-
L3MBTL2	83746	l(3)mbt-like 2 (Drosophila)	transcription, DNA-templated	Biological process	-
KLF5	688	Kruppel-like factor 5 (intestinal)	intracellular membrane-bounded organelle	Cellular component	-
CYP11B2	1585	cytochrome P450, family 11, subfamily B, polypeptide 2	C21-steroid hormone biosynthetic process	Biological process	2256920
TNRC18	84629	trinucleotide repeat containing 18	chromatin silencing complex	Cellular component	-
LIG4	3981	ligase IV, DNA, ATP-dependent	protein binding	Molecular function	11702069
C1R	715	complement component 1, r subcomponent	complement activation	Biological process	-
DCAF11	80344	DDB1 and CUL4 associated factor 11	Cul4-RING E3 ubiquitin ligase complex	Cellular component	16949367
STAR	6770	steroidogenic acute regulatory protein	diterpenoid metabolic process	Biological process	-
DCN	1634	decorin	poly(A) RNA binding	Molecular function	22658674
RACGAP1	29127	Rac GTPase activating protein 1	nucleoplasm	Cellular component	-
SNCA	6622	synuclein, alpha (non A4 component of amyloid precursor)	zinc ion binding	Molecular function	11850416
ACOT4	122970	acyl-CoA thioesterase 4	short-chain fatty acid metabolic process	Biological process	16940157
NEK3	4752	NIMA-related kinase 3	protein phosphorylation	Biological process	-
RCN2	5955	reticulocalbin 2, EF-hand calcium binding domain	endoplasmic reticulum	Cellular component	-
PRKD2	25865	protein kinase D2	protein kinase D signaling	Biological process	20497126
VAMP2	6844	vesicle-associated membrane protein 2 (synaptobrevin 2)	cytoplasmic vesicle	Cellular component	-
PVRL4	81607	poliovirus receptor-related 4	integral component of membrane	Cellular component	-
SIRT2	22933	sirtuin 2	positive regulation of meiotic nuclear division	Biological process	-
NCF4	4689	neutrophil cytosolic factor 4, 40kDa	phagosome maturation	Biological process	-
PER1	5187	period circadian clock 1	negative regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	-
NADK	65220	NAD kinase	vitamin metabolic process	Biological process	-
DRD2	1813	dopamine receptor D2	perikaryon	Cellular component	-
ERAP1	51752	endoplasmic reticulum aminopeptidase 1	positive regulation of angiogenesis	Biological process	-
BCAR1	9564	breast cancer anti-estrogen resistance 1	cell migration	Biological process	9425168
MRGPRX4	117196	MAS-related GPR, member X4	integral component of plasma membrane	Cellular component	-
ATP6V0B	533	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b	proton transport	Biological process	9653649
CDC7	8317	cell division cycle 7	positive regulation of nuclear cell cycle DNA replication	Biological process	15668232
GSPT1	2935	G1 to S phase transition 1	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Biological process	15326224
KIF18A	81930	kinesin family member 18A	actin binding	Molecular function	18680169
CDK6	1021	cyclin-dependent kinase 6	negative regulation of osteoblast differentiation	Biological process	15254224
BCR	613	breakpoint cluster region	Rho guanyl-nucleotide exchange factor activity	Molecular function	-
HLA-DRB4	3126	major histocompatibility complex, class II, DR beta 4	negative regulation of inflammatory response to antigenic stimulus	Biological process	18039812
MED1	5469	mediator complex subunit 1	organ regeneration	Biological process	-
PARK7	11315	parkinson protein 7	activation of protein kinase B activity	Biological process	22492997
HSP90B1	7184	heat shock protein 90kDa beta (Grp94), member 1	response to endoplasmic reticulum stress	Biological process	22934019
PRAMEF20	645425	PRAME family member 20	negative regulation of apoptotic process	Biological process	-
PPP1CA	5499	protein phosphatase 1, catalytic subunit, alpha isozyme	plasma membrane	Cellular component	-
CREB1	1385	cAMP responsive element binding protein 1	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity	Molecular function	19861239
GAGE1	2543	G antigen 1	protein binding	Molecular function	25416956
KCNC2	3747	potassium channel, voltage gated Shaw related subfamily C, member 2	cellular response to nitric oxide	Biological process	-
SUMF1	285362	sulfatase modifying factor 1	protein homodimerization activity	Molecular function	-
FNDC1	84624	fibronectin type III domain containing 1	positive regulation of cardiac muscle cell apoptotic process	Biological process	-
CRLF1	9244	cytokine receptor-like factor 1	ureteric bud development	Biological process	-
PHC3	80012	polyhomeotic homolog 3 (Drosophila)	intracellular membrane-bounded organelle	Cellular component	-
GATC	283459	glutamyl-tRNA(Gln) amidotransferase, subunit C	regulation of translational fidelity	Biological process	-
FAU	2197	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed	viral process	Biological process	-
SDS	10993	serine dehydratase	protein homodimerization activity	Molecular function	15689518
HGS	9146	hepatocyte growth factor-regulated tyrosine kinase substrate	metal ion binding	Molecular function	-
OR11L1	391189	olfactory receptor, family 11, subfamily L, member 1	G-protein coupled receptor signaling pathway	Biological process	-
TLE3	7090	transducin-like enhancer of split 3	transcription, DNA-templated	Biological process	-
STX3	6809	syntaxin 3	positive regulation of cell adhesion	Biological process	21720706
SPSB2	84727	splA/ryanodine receptor domain and SOCS box containing 2	protein ubiquitination	Biological process	-
MITD1	129531	MIT, microtubule interacting and transport, domain containing 1	viral budding via host ESCRT complex	Biological process	23045692
CCAR2	57805	cell cycle and apoptosis regulator 2	nucleus	Cellular component	-
ZNF10	7556	zinc finger protein 10	metal ion binding	Molecular function	-
PRNP	5621	prion protein	cellular copper ion homeostasis	Biological process	16004966
B2M	567	beta-2-microglobulin	viral process	Biological process	-
LRRFIP2	9209	leucine rich repeat (in FLII) interacting protein 2	cellular_component	Cellular component	-
ITGB3	3690	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	leukocyte migration	Biological process	-
LHX1	3975	LIM homeobox 1	positive regulation of nephron tubule epithelial cell differentiation	Biological process	-
PDILT	204474	protein disulfide isomerase-like, testis expressed	protein folding	Biological process	-
LTB4R	1241	leukotriene B4 receptor	integral component of plasma membrane	Cellular component	9177352
KDM5B	10765	lysine (K)-specific demethylase 5B	histone demethylase activity (H3-dimethyl-K4 specific)	Molecular function	20228790
FKBP1A	2280	FK506 binding protein 1A, 12kDa	regulation of amyloid precursor protein catabolic process	Biological process	24499793
PKN2	5586	protein kinase N2	regulation of cell motility	Biological process	21754995
GUCA1B	2979	guanylate cyclase activator 1B (retina)	regulation of rhodopsin mediated signaling pathway	Biological process	-
SGK1	6446	serum/glucocorticoid regulated kinase 1	response to stress	Biological process	9114008
SLC2A5	6518	solute carrier family 2 (facilitated glucose/fructose transporter), member 5	integral component of plasma membrane	Cellular component	-
PLCL2	23228	phospholipase C-like 2	B-1a B cell differentiation	Biological process	-
TXNDC17	84817	thioredoxin domain containing 17	peroxidase activity	Molecular function	14607844
RYK	6259	receptor-like tyrosine kinase	Wnt signaling pathway	Biological process	-
SLC30A1	7779	solute carrier family 30 (zinc transporter), member 1	calcium channel inhibitor activity	Molecular function	-
CDKN1B	1027	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	phosphatidylinositol-mediated signaling	Biological process	-
SFRP5	6425	secreted frizzled-related protein 5	negative regulation of catenin import into nucleus	Biological process	19957335
SLC4A7	9497	solute carrier family 4, sodium bicarbonate cotransporter, member 7	apical plasma membrane	Cellular component	-
NLGN2	57555	neuroligin 2	positive regulation of synaptic transmission, GABAergic	Biological process	-
SLC10A5	347051	solute carrier family 10, member 5	integral component of plasma membrane	Cellular component	-
KCNQ3	3786	potassium channel, voltage gated KQT-like subfamily Q, member 3	voltage-gated potassium channel complex	Cellular component	-
ZMYM6	9204	zinc finger, MYM-type 6	regulation of cell morphogenesis	Biological process	21834987
NUDT4	11163	nudix (nucleoside diphosphate linked moiety X)-type motif 4	inositol phosphate metabolic process	Biological process	-
CRYAB	1410	crystallin, alpha B	cytosol	Cellular component	-
USP51	158880	ubiquitin specific peptidase 51	SAGA complex	Cellular component	-
ANAPC11	51529	anaphase promoting complex subunit 11	ubiquitin-ubiquitin ligase activity	Molecular function	10230407
FFAR4	338557	free fatty acid receptor 4	positive regulation of ERK1 and ERK2 cascade	Biological process	-
PCBP4	57060	poly(rC) binding protein 4	poly(A) RNA binding	Molecular function	22658674
CDC42	998	cell division cycle 42	apical part of cell	Cellular component	-
UXT	8409	ubiquitously-expressed, prefoldin-like chaperone	beta-tubulin binding	Molecular function	12762840
BMX	660	BMX non-receptor tyrosine kinase	signal transduction	Biological process	10688651
TRIM72	493829	tripartite motif containing 72, E3 ubiquitin protein ligase	protein homooligomerization	Biological process	-
EIF2S3	1968	eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa	translation factor activity, RNA binding	Molecular function	10900014
VAMP2	6844	vesicle-associated membrane protein 2 (synaptobrevin 2)	phospholipid binding	Molecular function	-
PARVG	64098	parvin, gamma	protein binding	Molecular function	25416956
ACSL4	2182	acyl-CoA synthetase long-chain family member 4	fatty acid transport	Biological process	-
TRIM24	8805	tripartite motif containing 24	negative regulation of transcription, DNA-templated	Biological process	-
GLI3	2737	GLI family zinc finger 3	positive regulation of transcription from RNA polymerase II promoter	Biological process	18559511
ADD2	119	adducin 2 (beta)	transmembrane transport	Biological process	-
POLR2F	5435	polymerase (RNA) II (DNA directed) polypeptide F	transcription elongation from RNA polymerase I promoter	Biological process	-
ZFP41	286128	ZFP41 zinc finger protein	cell differentiation	Biological process	-
RHBDD1	84236	rhomboid domain containing 1	regulation of male germ cell proliferation	Biological process	-
LPGAT1	9926	lysophosphatidylglycerol acyltransferase 1	phosphatidylglycerol acyl-chain remodeling	Biological process	-
DDX21	9188	DEAD (Asp-Glu-Ala-Asp) box helicase 21	nucleolus	Cellular component	-
HS6ST2	90161	heparan sulfate 6-O-sulfotransferase 2	carbohydrate metabolic process	Biological process	-
RUSC1	23623	RUN and SH3 domain containing 1	cytoplasmic membrane-bounded vesicle	Cellular component	-
OTOG	340990	otogelin	sensory perception of sound	Biological process	-
CRHR1	1394	corticotropin releasing hormone receptor 1	regulation of corticosterone secretion	Biological process	-
DHCR7	1717	7-dehydrocholesterol reductase	7-dehydrocholesterol reductase activity	Molecular function	9465114
MSX2	4488	msh homeobox 2	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	-
AIP	9049	aryl hydrocarbon receptor interacting protein	unfolded protein binding	Molecular function	14557246
ROCK2	9475	Rho-associated, coiled-coil containing protein kinase 2	regulation of stress fiber assembly	Biological process	12778124
NDRG1	10397	N-myc downstream regulated 1	cellular response to hypoxia	Biological process	20810912
SLC26A11	284129	solute carrier family 26 (anion exchanger), member 11	lysosomal membrane	Cellular component	20957757
RNF41	10193	ring finger protein 41, E3 ubiquitin protein ligase	zinc ion binding	Molecular function	-
F2RL1	2150	coagulation factor II (thrombin) receptor-like 1	negative regulation of tumor necrosis factor-mediated signaling pathway	Biological process	19781631
ADGRE1	2015	adhesion G protein-coupled receptor E1	external side of plasma membrane	Cellular component	-
TIMM23B	100652748	translocase of inner mitochondrial membrane 23 homolog B (yeast)	biological_process	Biological process	-
PTGS2	5743	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	response to vitamin D	Biological process	-
SLC30A7	148867	solute carrier family 30 (zinc transporter), member 7	cytoplasm	Cellular component	17349999
CLU	1191	clusterin	chaperone-mediated protein folding	Biological process	11123922
SPATA25	128497	spermatogenesis associated 25	integral component of membrane	Cellular component	-
CBL	867	Cbl proto-oncogene, E3 ubiquitin protein ligase	signal transducer activity	Molecular function	-
PBRM1	55193	polybromo 1	negative regulation of cell proliferation	Biological process	21248752
DBNL	28988	drebrin-like	protein C-terminus binding	Molecular function	-
LMBRD1	55788	LMBR1 domain containing 1	small molecule metabolic process	Biological process	-
APOA2	336	apolipoprotein A-II	diacylglycerol catabolic process	Biological process	14967812
FUOM	282969	fucose mutarotase	racemase and epimerase activity, acting on carbohydrates and derivatives	Molecular function	-
LRP1	4035	low density lipoprotein receptor-related protein 1	regulation of cholesterol transport	Biological process	-
IFI44L	10964	interferon-induced protein 44-like	cytoplasm	Cellular component	-
ARFGEF1	10565	ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)	cytoplasm	Cellular component	-
WNT3	7473	wingless-type MMTV integration site family, member 3	protein domain specific binding	Molecular function	-
CYP19A1	1588	cytochrome P450, family 19, subfamily A, polypeptide 1	steroid metabolic process	Biological process	-
RPL37A	6168	ribosomal protein L37a	metal ion binding	Molecular function	-
PRKCD	5580	protein kinase C, delta	cellular component disassembly involved in execution phase of apoptosis	Biological process	-
TFDP3	51270	transcription factor Dp family, member 3	sequence-specific DNA binding RNA polymerase II transcription factor activity	Molecular function	-
IL34	146433	interleukin 34	inflammatory response	Biological process	-
PKP4	8502	plakophilin 4	cell-cell signaling	Biological process	8937994
HMMR	3161	hyaluronan-mediated motility receptor (RHAMM)	membrane	Cellular component	19946888
PRDM7	11105	PR domain containing 7	nucleic acid binding	Molecular function	-
ZNF860	344787	zinc finger protein 860	transcription, DNA-templated	Biological process	-
WNT9B	7484	wingless-type MMTV integration site family, member 9B	neuron differentiation	Biological process	-
KLRD1	3824	killer cell lectin-like receptor subfamily D, member 1	protein binding	Molecular function	18448674
SEC14L4	284904	SEC14-like 4 (S. cerevisiae)	intracellular	Cellular component	-
BCL11B	64919	B-cell CLL/lymphoma 11B (zinc finger protein)	thymus development	Biological process	-
SEC61A2	55176	Sec61 alpha 2 subunit (S. cerevisiae)	cellular protein metabolic process	Biological process	-
ARFGAP1	55738	ADP-ribosylation factor GTPase activating protein 1	retrograde vesicle-mediated transport, Golgi to ER	Biological process	-
AKAP6	9472	A kinase (PRKA) anchor protein 6	protein binding	Molecular function	17923693
SUV39H2	79723	suppressor of variegation 3-9 homolog 2 (Drosophila)	negative regulation of transcription from RNA polymerase II promoter	Biological process	21402781
SLC11A2	4891	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2	cobalt ion transport	Biological process	-
ESR1	2099	estrogen receptor 1	integral component of membrane	Cellular component	-
DAG1	1605	dystroglycan 1 (dystrophin-associated glycoprotein 1)	cytoplasm	Cellular component	18764929
TNKS2	80351	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2	positive regulation of canonical Wnt signaling pathway	Biological process	-
SCEL	8796	sciellin	protein binding	Molecular function	14632196
MYO6	4646	myosin VI	actin filament-based movement	Biological process	10519557
MYO18A	399687	myosin XVIIIA	Golgi membrane	Cellular component	19837035
WHSC1	7468	Wolf-Hirschhorn syndrome candidate 1	bone development	Biological process	-
NR3C1	2908	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	steroid binding	Molecular function	15769988
NUAK1	9891	NUAK family, SNF1-like kinase, 1	regulation of cell proliferation	Biological process	21317932
AGO4	192670	argonaute RISC catalytic component 4	Fc-epsilon receptor signaling pathway	Biological process	-
BCAM	4059	basal cell adhesion molecule (Lutheran blood group)	signal transduction	Biological process	7777537
NTF3	4908	neurotrophin 3	activation of MAPK activity	Biological process	23027130
MSH2	4436	mutS homolog 2	four-way junction DNA binding	Molecular function	12034830
ANAPC10	10393	anaphase promoting complex subunit 10	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	Biological process	-
MICA	100507436	MHC class I polypeptide-related sequence A	beta-2-microglobulin binding	Molecular function	8901601
NPHS2	7827	nephrosis 2, idiopathic, steroid-resistant (podocin)	membrane raft	Cellular component	17675666
NRG1	3084	neuregulin 1	cardiac muscle cell differentiation	Biological process	-
GNB1	2782	guanine nucleotide binding protein (G protein), beta polypeptide 1	type 1 angiotensin receptor binding	Molecular function	-
KCNE3	10008	potassium channel, voltage gated subfamily E regulatory beta subunit 3	voltage-gated potassium channel activity	Molecular function	-
SAMD4A	23034	sterile alpha motif domain containing 4A	positive regulation of translation	Biological process	16221671
APLF	200558	aprataxin and PNKP like factor	endodeoxyribonuclease activity	Molecular function	17396150
LIN37	55957	lin-37 DREAM MuvB core complex component	G2/M transition of mitotic cell cycle	Biological process	-
CHAT	1103	choline O-acetyltransferase	cytosol	Cellular component	-
MEX3A	92312	mex-3 RNA binding family member A	poly(A) RNA binding	Molecular function	22681889
APP	351	amyloid beta (A4) precursor protein	apical part of cell	Cellular component	-
CREB3L1	90993	cAMP responsive element binding protein 3-like 1	transcription regulatory region DNA binding	Molecular function	-
GNL1	2794	guanine nucleotide binding protein-like 1	T cell mediated immunity	Biological process	8180467
PSME4	23198	proteasome (prosome, macropain) activator subunit 4	negative regulation of canonical Wnt signaling pathway	Biological process	-
AK4	205	adenylate kinase 4	nucleoside diphosphate kinase activity	Molecular function	23416111
SYP	6855	synaptophysin	presynaptic active zone	Cellular component	-
SUSD4	55061	sushi domain containing 4	regulation of complement activation	Biological process	23482636
PLXND1	23129	plexin D1	regulation of cell migration	Biological process	-
SECISBP2L	9728	SECIS binding protein 2-like	poly(A) RNA binding	Molecular function	22658674
TMEM161A	54929	transmembrane protein 161A	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	Biological process	16551573
PPARD	5467	peroxisome proliferator-activated receptor delta	positive regulation of transcription, DNA-templated	Biological process	12955147
HMG20B	10362	high mobility group 20B	negative regulation of protein sumoylation	Biological process	-
NUP153	9972	nucleoporin 153kDa	nuclear pore complex assembly	Biological process	12802065
SLC6A19	340024	solute carrier family 6 (neutral amino acid transporter), member 19	transmembrane transport	Biological process	-
TP73	7161	tumor protein p73	Golgi apparatus	Cellular component	-
PRPS2	5634	phosphoribosyl pyrophosphate synthetase 2	ATP binding	Molecular function	-
STAT5B	6777	signal transducer and activator of transcription 5B	response to lipopolysaccharide	Biological process	-
SMPDL3A	10924	sphingomyelin phosphodiesterase, acid-like 3A	biological_process	Biological process	-
TYMS	7298	thymidylate synthetase	response to ethanol	Biological process	-
ANG	283	angiogenin, ribonuclease, RNase A family, 5	rRNA binding	Molecular function	2457905
CABP1	9478	calcium binding protein 1	nuclear localization sequence binding	Molecular function	-
PIEZO2	63895	piezo-type mechanosensitive ion channel component 2	integral component of membrane	Cellular component	-
GALK1	2584	galactokinase 1	galactose binding	Molecular function	14596685
MED4	29079	mediator complex subunit 4	transcription initiation from RNA polymerase II promoter	Biological process	-
RBBP8	5932	retinoblastoma binding protein 8	negative regulation of transcription from RNA polymerase II promoter	Biological process	16287852
TNFSF4	7292	tumor necrosis factor (ligand) superfamily, member 4	response to nitrogen dioxide	Biological process	-
PRDM16	63976	PR domain containing 16	neurogenesis	Biological process	-
BMPER	168667	BMP binding endothelial regulator	endothelial cell differentiation	Biological process	-
MAFIP	727764	MAFF interacting protein (pseudogene)	regulation of transcription, DNA-templated	Biological process	-
WNT5A	7474	wingless-type MMTV integration site family, member 5A	planar cell polarity pathway involved in pericardium morphogenesis	Biological process	-
FLT3	2322	fms-related tyrosine kinase 3	regulation of apoptotic process	Biological process	19549778
ANP32A	8125	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	protein binding	Molecular function	16169070
SLC9A2	6549	solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2	plasma membrane	Cellular component	-
SERPINB3	6317	serpin peptidase inhibitor, clade B (ovalbumin), member 3	positive regulation of endopeptidase activity	Biological process	20527027
DDX39A	10212	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A	nucleus	Cellular component	21859714
SFXN3	81855	sideroflexin 3	iron ion homeostasis	Biological process	-
CANX	821	calnexin	ribosome	Cellular component	-
RAB11B	9230	RAB11B, member RAS oncogene family	regulated secretory pathway	Biological process	-
RPRD1B	58490	regulation of nuclear pre-mRNA domain containing 1B	protein binding	Molecular function	22264791
MKRN1	23608	makorin ring finger protein 1	protein polyubiquitination	Biological process	19536131
ATP6V0B	533	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b	ATP hydrolysis coupled proton transport	Biological process	-
ST8SIA2	8128	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	oligosaccharide metabolic process	Biological process	10766765
DAXX	1616	death-domain associated protein	enzyme binding	Molecular function	16845383
RPS19	6223	ribosomal protein S19	translational elongation	Biological process	-
IL6ST	3572	interleukin 6 signal transducer	regulation of Notch signaling pathway	Biological process	-
SPIDR	23514	scaffolding protein involved in DNA repair	cellular response to hydroxyurea	Biological process	23509288
EIF2AK3	9451	eukaryotic translation initiation factor 2-alpha kinase 3	protein homodimerization activity	Molecular function	22934019
ZNF852	285346	zinc finger protein 852	nucleus	Cellular component	-
CCNA2	890	cyclin A2	mitotic nuclear division	Biological process	-
CDKN2A	1029	cyclin-dependent kinase inhibitor 2A	positive regulation of protein sumoylation	Biological process	19057511
ITGAV	3685	integrin, alpha V	cell migration	Biological process	22505472
YIPF5	81555	Yip1 domain family, member 5	endoplasmic reticulum membrane	Cellular component	-
DNAJA3	9093	DnaJ (Hsp40) homolog, subfamily A, member 3	transcription factor binding	Molecular function	16531398
PCDH9	5101	protocadherin 9	calcium ion binding	Molecular function	-
PSMA1	5682	proteasome (prosome, macropain) subunit, alpha type, 1	programmed cell death	Biological process	-
ATRN	8455	attractin	cerebellum development	Biological process	-
MYO6	4646	myosin VI	axon	Cellular component	-
TNK2	10188	tyrosine kinase, non-receptor, 2	protein tyrosine kinase activity	Molecular function	18993068
VIL1	7429	villin 1	regulation of lamellipodium morphogenesis	Biological process	-
DBH	1621	dopamine beta-hydroxylase (dopamine beta-monooxygenase)	behavioral response to ethanol	Biological process	-
DCC	1630	DCC netrin 1 receptor	negative regulation of dendrite development	Biological process	19616629
TRIM17	51127	tripartite motif containing 17	cellular_component	Cellular component	-
NGF	4803	nerve growth factor (beta polypeptide)	activation of phospholipase C activity	Biological process	-
DNAAF2	55172	dynein, axonemal, assembly factor 2	axonemal dynein complex assembly	Biological process	19052621
TICAM2	353376	toll-like receptor adaptor molecule 2	late endosome membrane	Cellular component	-
CSRP2BP	57325	CSRP2 binding protein	nucleus	Cellular component	10924333
RNF146	81847	ring finger protein 146	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	21478859
ATP2B4	493	ATPase, Ca++ transporting, plasma membrane 4	calcium-transporting ATPase activity	Molecular function	8530416
COQ3	51805	coenzyme Q3 methyltransferase	decaprenyldihydroxybenzoate methyltransferase activity	Molecular function	-
KCNK7	10089	potassium channel, two pore domain subfamily K, member 7	potassium ion transmembrane transport	Biological process	-
EIF3A	8661	eukaryotic translation initiation factor 3, subunit A	gene expression	Biological process	-
CCL4	6351	chemokine (C-C motif) ligand 4	movement of cell or subcellular component	Biological process	9759849
PSME3	10197	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)	cytosol	Cellular component	-
IL33	90865	interleukin 33	positive regulation of chemokine secretion	Biological process	19841166
GABPA	2551	GA binding protein transcription factor, alpha subunit 60kDa	organelle organization	Biological process	-
IRF9	10379	interferon regulatory factor 9	transcription from RNA polymerase II promoter	Biological process	1630447
CNOT4	4850	CCR4-NOT transcription complex, subunit 4	ligase activity	Molecular function	-
HEPH	9843	hephaestin	intracellular	Cellular component	20019163
GPAM	57678	glycerol-3-phosphate acyltransferase, mitochondrial	CDP-diacylglycerol biosynthetic process	Biological process	-
MED18	54797	mediator complex subunit 18	protein binding	Molecular function	12584197
ACTR3	10096	ARP3 actin-related protein 3 homolog (yeast)	excitatory synapse	Cellular component	-
TACR1	6869	tachykinin receptor 1	plasma membrane	Cellular component	-
TUBB6	84617	tubulin, beta 6 class V	microtubule	Cellular component	21525035
FGF13	2258	fibroblast growth factor 13	signal transduction	Biological process	8790420
BDKRB1	623	bradykinin receptor B1	negative regulation of protein phosphorylation	Biological process	-
IKBKB	3551	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	toll-like receptor 2 signaling pathway	Biological process	-
RAD23B	5887	RAD23 homolog B (S. cerevisiae)	DNA repair	Biological process	-
ALG11	440138	ALG11, alpha-1,2-mannosyltransferase	integral component of membrane	Cellular component	-
BAMBI	25805	BMP and activin membrane-bound inhibitor	positive regulation of protein binding	Biological process	18838381
TDRD12	91646	tudor domain containing 12	piRNA metabolic process	Biological process	-
PSD4	23550	pleckstrin and Sec7 domain containing 4	ARF guanyl-nucleotide exchange factor activity	Molecular function	-
MRPS15	64960	mitochondrial ribosomal protein S15	mitochondrial small ribosomal subunit	Cellular component	11279123
PIFO	128344	primary cilia formation	cytoplasmic membrane-bounded vesicle	Cellular component	-
WDR59	79726	WD repeat domain 59	biological_process	Biological process	-
PKN1	5585	protein kinase N1	cytoplasmic membrane-bounded vesicle	Cellular component	-
NOP14	8602	NOP14 nucleolar protein	poly(A) RNA binding	Molecular function	22658674
SLC18A3	6572	solute carrier family 18 (vesicular acetylcholine transporter), member 3	acetylcholine transport	Biological process	8071310
SIX1	6495	SIX homeobox 1	thymus development	Biological process	-
ALK	238	anaplastic lymphoma receptor tyrosine kinase	cell proliferation	Biological process	19459784
PDZRN4	29951	PDZ domain containing ring finger 4	protein ubiquitination	Biological process	-
SMAD7	4092	SMAD family member 7	positive regulation of protein ubiquitination	Biological process	16720724
CRTC3	64784	CREB regulated transcription coactivator 3	negative regulation of lipid catabolic process	Biological process	-
NR2F6	2063	nuclear receptor subfamily 2, group F, member 6	intracellular receptor signaling pathway	Biological process	2905047
DOCK1	1793	dedicator of cytokinesis 1	signal transduction	Biological process	8661160
ABCF3	55324	ATP-binding cassette, sub-family F (GCN20), member 3	membrane	Cellular component	19946888
RNASEH2B	79621	ribonuclease H2, subunit B	nucleus	Cellular component	-
SPOCK1	6695	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1	node of Ranvier	Cellular component	-
CASP8	841	caspase 8, apoptosis-related cysteine peptidase	cytoskeleton	Cellular component	10891503
XRCC5	7520	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	transcription, DNA-templated	Biological process	-
NFIX	4784	nuclear factor I/X (CCAAT-binding transcription factor)	nucleus	Cellular component	-
ZNF32	7580	zinc finger protein 32	DNA binding	Molecular function	-
SPEG	10290	SPEG complex locus	muscle organ development	Biological process	8663449
THNSL2	55258	threonine synthase-like 2 (S. cerevisiae)	cellular_component	Cellular component	-
ALMS1	7840	Alstrom syndrome protein 1	organelle organization	Biological process	-
BOP1	23246	block of proliferation 1	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Biological process	17353269
UFD1L	7353	ubiquitin fusion degradation 1 like (yeast)	translesion synthesis	Biological process	-
ZNF460	10794	zinc finger protein 460	protein binding	Molecular function	25416956
HIST1H1D	3007	histone cluster 1, H1d	nuclear euchromatin	Cellular component	15911621
LGALS1	3956	lectin, galactoside-binding, soluble, 1	proteinaceous extracellular matrix	Cellular component	-
INO80	54617	INO80 complex subunit	nucleus	Cellular component	-
TCP10L	140290	t-complex 10-like	RNA polymerase II transcription corepressor activity	Molecular function	14586771
APOD	347	apolipoprotein D	tissue regeneration	Biological process	-
OPRD1	4985	opioid receptor, delta 1	protein binding	Molecular function	15086532
ADAMTS8	11095	ADAM metallopeptidase with thrombospondin type 1 motif, 8	heparin binding	Molecular function	-
GCK	2645	glucokinase (hexokinase 4)	fructokinase activity	Molecular function	-
GALNT13	114805	polypeptide N-acetylgalactosaminyltransferase 13	polypeptide N-acetylgalactosaminyltransferase activity	Molecular function	-
BAG6	7917	BCL2-associated athanogene 6	ubiquitin protein ligase binding	Molecular function	24981174
VPS28	51160	vacuolar protein sorting 28 homolog (S. cerevisiae)	viral life cycle	Biological process	-
ILVBL	10994	ilvB (bacterial acetolactate synthase)-like	protein binding	Molecular function	25416956
PPP1R15A	23645	protein phosphatase 1, regulatory subunit 15A	endoplasmic reticulum membrane	Cellular component	21518769
NLGN1	22871	neuroligin 1	dendritic spine	Cellular component	-
RAPGEF4	11069	Rap guanine nucleotide exchange factor (GEF) 4	Ras guanyl-nucleotide exchange factor activity	Molecular function	-
CFL2	1073	cofilin 2 (muscle)	actin filament depolymerization	Biological process	-
AGRP	181	agouti related neuropeptide	regulation of feeding behavior	Biological process	9311920
IRAK4	51135	interleukin-1 receptor-associated kinase 4	protein kinase activity	Molecular function	-
ORC4	5000	origin recognition complex, subunit 4	nucleotide binding	Molecular function	9353276
PPIAL4C	653598	peptidylprolyl isomerase A (cyclophilin A)-like 4C	protein peptidyl-prolyl isomerization	Biological process	-
APLN	8862	apelin	regulation of respiratory gaseous exchange	Biological process	-
MLKL	197259	mixed lineage kinase domain-like	programmed cell death	Biological process	-
RNF146	81847	ring finger protein 146	zinc ion binding	Molecular function	-
GGT1	2678	gamma-glutamyltransferase 1	integral component of membrane	Cellular component	-
MAP2K2	5605	mitogen-activated protein kinase kinase 2	regulation of early endosome to late endosome transport	Biological process	19565474
PIK3R4	30849	phosphoinositide-3-kinase, regulatory subunit 4	phospholipid metabolic process	Biological process	-
DGUOK	1716	deoxyguanosine kinase	cytosol	Cellular component	-
COMMD1	150684	copper metabolism (Murr1) domain containing 1	copper ion binding	Molecular function	17309234
SULT1A2	6799	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2	protein binding	Molecular function	25416956
HFE2	148738	hemochromatosis type 2 (juvenile)	anchored component of membrane	Cellular component	-
IGKC	3514	immunoglobulin kappa constant	complement activation, classical pathway	Biological process	-
PI4KAP2	375133	phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 2	phosphatidylinositol phosphorylation	Biological process	-
NTRK1	4914	neurotrophic tyrosine kinase, receptor, type 1	late endosome	Cellular component	-
MPHOSPH6	10200	M-phase phosphoprotein 6	nucleolus	Cellular component	-
PPP4C	5531	protein phosphatase 4, catalytic subunit	metal ion binding	Molecular function	-
ANXA4	307	annexin A4	signal transduction	Biological process	16130169
KNTC1	9735	kinetochore associated 1	small GTPase mediated signal transduction	Biological process	-
TMEM68	137695	transmembrane protein 68	integral component of membrane	Cellular component	-
CYP2C9	1559	cytochrome P450, family 2, subfamily C, polypeptide 9	intracellular membrane-bounded organelle	Cellular component	2827463
ATP1A3	478	ATPase, Na+/K+ transporting, alpha 3 polypeptide	response to glycoside	Biological process	11546672
SLC2A3	6515	solute carrier family 2 (facilitated glucose transporter), member 3	hexose transmembrane transport	Biological process	-
REXO1	57455	REX1, RNA exonuclease 1 homolog (S. cerevisiae)	nucleic acid binding	Molecular function	-
OR5I1	10798	olfactory receptor, family 5, subfamily I, member 1	olfactory receptor activity	Molecular function	-
PROP1	5626	PROP paired-like homeobox 1	transcription factor complex	Cellular component	-
TYW1	55253	tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)	cytoplasm	Cellular component	-
MEF2A	4205	myocyte enhancer factor 2A	toll-like receptor 9 signaling pathway	Biological process	-
PTK2B	2185	protein tyrosine kinase 2 beta	dendrite	Cellular component	-
NCS1	23413	neuronal calcium sensor 1	intracellular membrane-bounded organelle	Cellular component	-
SAP18	10284	Sin3A-associated protein, 18kDa	regulation of alternative mRNA splicing, via spliceosome	Biological process	22203037
SAFB2	9667	scaffold attachment factor B2	transcription, DNA-templated	Biological process	-
COG3	83548	component of oligomeric golgi complex 3	protein stabilization	Biological process	16420527
STXBP1	6812	syntaxin binding protein 1	extracellular exosome	Cellular component	19056867
TAF9	6880	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	Biological process	15899866
BCL2	596	B-cell CLL/lymphoma 2	response to glucocorticoid	Biological process	-
HLA-DRB4	3126	major histocompatibility complex, class II, DR beta 4	interferon-gamma-mediated signaling pathway	Biological process	-
PSME2	5721	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)	innate immune response	Biological process	-
ACSS2	55902	acyl-CoA synthetase short-chain family member 2	ethanol oxidation	Biological process	-
POLR1D	51082	polymerase (RNA) I polypeptide D, 16kDa	transcription initiation from RNA polymerase I promoter	Biological process	-
CXCL12	6387	chemokine (C-X-C motif) ligand 12	chemokine-mediated signaling pathway	Biological process	20388803
SEZ6L	23544	seizure related 6 homolog (mouse)-like	endoplasmic reticulum membrane	Cellular component	-
FKBP9	11328	FK506 binding protein 9, 63 kDa	protein folding	Biological process	-
PML	5371	promyelocytic leukemia	negative regulation of cell growth	Biological process	7935403
ERN1	2081	endoplasmic reticulum to nucleus signaling 1	identical protein binding	Molecular function	12637535
PPP2R3B	28227	protein phosphatase 2, regulatory subunit B'', beta	G1/S transition of mitotic cell cycle	Biological process	-
WNT16	51384	wingless-type MMTV integration site family, member 16	neuron differentiation	Biological process	-
RHOQ	23433	ras homolog family member Q	profilin binding	Molecular function	10445846
BTN2A3P	54718	butyrophilin, subfamily 2, member A3, pseudogene	integral component of membrane	Cellular component	-
NCAN	1463	neurocan	skeletal system development	Biological process	-
CPE	1363	carboxypeptidase E	zinc ion binding	Molecular function	-
NEUROD2	4761	neuronal differentiation 2	negative regulation of synapse maturation	Biological process	-
NR2C2	7182	nuclear receptor subfamily 2, group C, member 2	spermatogenesis	Biological process	-
FYN	2534	FYN proto-oncogene, Src family tyrosine kinase	forebrain development	Biological process	-
LIPE	3991	lipase, hormone-sensitive	lipid particle	Cellular component	-
TNNC1	7134	troponin C type 1 (slow)	regulation of muscle filament sliding speed	Biological process	-
CAMKK2	10645	calcium/calmodulin-dependent protein kinase kinase 2, beta	intracellular	Cellular component	11395482
GSTM4	2948	glutathione S-transferase mu 4	small molecule metabolic process	Biological process	-
TYMP	1890	thymidine phosphorylase	phosphorylase activity	Molecular function	-
NEDD9	4739	neural precursor cell expressed, developmentally down-regulated 9	actin filament bundle assembly	Biological process	11827972
VEGFA	7422	vascular endothelial growth factor A	protein binding	Molecular function	10543948
DSC2	1824	desmocollin 2	cell-cell adherens junction	Cellular component	-
OR2A1	346528	olfactory receptor, family 2, subfamily A, member 1	integral component of membrane	Cellular component	-
USP17L23	101241878	ubiquitin specific peptidase 17-like family member 23	nucleus	Cellular component	-
ATP5A1	498	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle	mitochondrial ATP synthesis coupled proton transport	Biological process	-
KIFC2	90990	kinesin family member C2	ATP binding	Molecular function	-
OPRK1	4986	opioid receptor, kappa 1	opioid receptor activity	Molecular function	22437504
GPR150	285601	G protein-coupled receptor 150	integral component of membrane	Cellular component	-
SASH3	54440	SAM and SH3 domain containing 3	positive regulation of organ growth	Biological process	-
OR6A2	8590	olfactory receptor, family 6, subfamily A, member 2	sensory perception of smell	Biological process	14983052
EIF4A3	9775	eukaryotic translation initiation factor 4A3	cytoplasm	Cellular component	10523622
ODAM	54959	odontogenic, ameloblast asssociated	nucleus	Cellular component	-
PTPN1	5770	protein tyrosine phosphatase, non-receptor type 1	cytokine-mediated signaling pathway	Biological process	-
TRIM67	440730	tripartite motif containing 67	positive regulation of neuron projection development	Biological process	-
NUMA1	4926	nuclear mitotic apparatus protein 1	meiotic cell cycle	Biological process	-
CYP21A2	1589	cytochrome P450, family 21, subfamily A, polypeptide 2	glucocorticoid biosynthetic process	Biological process	-
FBXL2	25827	F-box and leucine-rich repeat protein 2	membrane	Cellular component	15893726
ADGRF3	165082	adhesion G protein-coupled receptor F3	integral component of membrane	Cellular component	-
CSTB	1476	cystatin B (stefin B)	negative regulation of endopeptidase activity	Biological process	3053245
MASP1	5648	mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)	proteolysis	Biological process	-
FEZF1	389549	FEZ family zinc finger 1	negative regulation of cell proliferation	Biological process	-
AHNAK	79026	AHNAK nucleoprotein	membrane	Cellular component	19946888
STAG1	10274	stromal antigen 1	nucleoplasm	Cellular component	-
CCL25	6370	chemokine (C-C motif) ligand 25	immune response	Biological process	-
ZSCAN21	7589	zinc finger and SCAN domain containing 21	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	19549071
PDK2	5164	pyruvate dehydrogenase kinase, isozyme 2	cellular response to reactive oxygen species	Biological process	21283817
STX4	6810	syntaxin 4	intracellular protein transport	Biological process	-
TTN	7273	titin	sarcomerogenesis	Biological process	9817758
PIK3CD	5293	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	T cell differentiation	Biological process	20940048
GAD2	2572	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)	neurotransmitter biosynthetic process	Biological process	-
RABIF	5877	RAB interacting factor	small GTPase mediated signal transduction	Biological process	-
PARK2	5071	parkin RBR E3 ubiquitin protein ligase	negative regulation of glucokinase activity	Biological process	24187134
DUSP15	128853	dual specificity phosphatase 15	regulation of cell proliferation	Biological process	-
TAF7L	54457	TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa	transcription factor binding	Molecular function	-
RAD51	5888	RAD51 recombinase	PML body	Cellular component	11309417
TLR9	54106	toll-like receptor 9	negative regulation of calcium-transporting ATPase activity	Biological process	24610369
FGF13	2258	fibroblast growth factor 13	nervous system development	Biological process	8790420
KIT	3815	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	epidermal growth factor receptor signaling pathway	Biological process	-
KCNK1	3775	potassium channel, two pore domain subfamily K, member 1	potassium ion transport	Biological process	8605869
CYCS	54205	cytochrome c, somatic	small molecule metabolic process	Biological process	-
CYP4F12	66002	cytochrome P450, family 4, subfamily F, polypeptide 12	xenobiotic metabolic process	Biological process	-
SNCAIP	9627	synuclein, alpha interacting protein	neuronal cell body	Cellular component	11956199
KCNN1	3780	potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1	cytoplasm	Cellular component	-
SYN1	6853	synapsin I	catalytic activity	Molecular function	-
NOTCH1	4851	notch 1	regulation of extracellular matrix assembly	Biological process	-
TGFB1	7040	transforming growth factor, beta 1	mononuclear cell proliferation	Biological process	-
DYNC2LI1	51626	dynein, cytoplasmic 2, light intermediate chain 1	determination of left/right symmetry	Biological process	-
SLC26A8	116369	solute carrier family 26 (anion exchanger), member 8	sulfate transmembrane transporter activity	Molecular function	1183472
HSPA1A	3303	heat shock 70kDa protein 1A	negative regulation of protein ubiquitination	Biological process	12150907
RPS20	6224	ribosomal protein S20	protein binding	Molecular function	18274552
ATP7A	538	ATPase, Cu++ transporting, alpha polypeptide	locomotory behavior	Biological process	-
LPIN1	23175	lipin 1	small molecule metabolic process	Biological process	-
MRGPRX2	117194	MAS-related GPR, member X2	integral component of plasma membrane	Cellular component	-
ERN1	2081	endoplasmic reticulum to nucleus signaling 1	regulation of macroautophagy	Biological process	22013210
CPLX3	594855	complexin 3	syntaxin binding	Molecular function	-
UHRF2	115426	ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase	ubiquitin protein ligase activity	Molecular function	14741369
NCBP1	4686	nuclear cap binding protein subunit 1, 80kDa	nucleoplasm	Cellular component	-
PTPN23	25930	protein tyrosine phosphatase, non-receptor type 23	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	Biological process	21757351
SOX6	55553	SRY (sex determining region Y)-box 6	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
GATA4	2626	GATA binding protein 4	zinc ion binding	Molecular function	-
CDKN2C	1031	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	negative regulation of cell proliferation	Biological process	10208428
SLC16A1	6566	solute carrier family 16 (monocarboxylate transporter), member 1	centrosome	Cellular component	23816619
INPP5J	27124	inositol polyphosphate-5-phosphatase J	small molecule metabolic process	Biological process	-
CBX7	23492	chromobox homolog 7	single-stranded RNA binding	Molecular function	-
AKIP1	56672	A kinase (PRKA) interacting protein 1	substrate adhesion-dependent cell spreading	Biological process	-
PRKAA2	5563	protein kinase, AMP-activated, alpha 2 catalytic subunit	transcription initiation from RNA polymerase II promoter	Biological process	-
SLC6A20	54716	solute carrier family 6 (proline IMINO transporter), member 20	neurotransmitter:sodium symporter activity	Molecular function	-
FAM213B	127281	family with sequence similarity 213, member B	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Molecular function	-
NFATC2IP	84901	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein	cytokine production	Biological process	-
MAVS	57506	mitochondrial antiviral signaling protein	positive regulation of chemokine (C-C motif) ligand 5 production	Biological process	16127453
AGFG1	3267	ArfGAP with FG repeats 1	spermatid nucleus differentiation	Biological process	-
PTX3	5806	pentraxin 3, long	complement component C1q binding	Molecular function	23544079
DOLPP1	57171	dolichyldiphosphatase 1	dolichyldiphosphatase activity	Molecular function	-
SIT1	27240	signaling threshold regulating transmembrane adaptor 1	regulation of T cell activation	Biological process	10209036
FBXO5	26271	F-box protein 5	metaphase/anaphase transition of mitotic cell cycle	Biological process	-
ZNF876P	642280	zinc finger protein 876, pseudogene	nucleus	Cellular component	-
RPSA	3921	ribosomal protein SA	cytosol	Cellular component	-
GALT	2592	galactose-1-phosphate uridylyltransferase	carbohydrate metabolic process	Biological process	-
BMF	90427	Bcl2 modifying factor	intrinsic apoptotic signaling pathway	Biological process	-
MYO7A	4647	myosin VIIA	protein binding	Molecular function	11964381
SOD1	6647	superoxide dismutase 1, soluble	regulation of T cell differentiation in thymus	Biological process	16716898
FOS	2353	FBJ murine osteosarcoma viral oncogene homolog	regulation of sequence-specific DNA binding transcription factor activity	Biological process	-
SLC16A1	6566	solute carrier family 16 (monocarboxylate transporter), member 1	plasma membrane lactate transport	Biological process	-
TTC21B	79809	tetratricopeptide repeat domain 21B	ventricular system development	Biological process	-
CREB3	10488	cAMP responsive element binding protein 3	induction of positive chemotaxis	Biological process	15001559
IMPDH2	3615	IMP (inosine 5'-monophosphate) dehydrogenase 2	retina development in camera-type eye	Biological process	-
RITA1	84934	RBPJ interacting and tubulin associated 1	centrosome	Cellular component	21102556
ARHGEF11	9826	Rho guanine nucleotide exchange factor (GEF) 11	regulation of cell growth	Biological process	10026210
ITGA3	3675	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	response to gonadotropin	Biological process	-
SIAH2	6478	siah E3 ubiquitin protein ligase 2	protein binding	Molecular function	21586138
TSPAN1	10103	tetraspanin 1	positive regulation of endocytosis	Biological process	22378020
KLF11	8462	Kruppel-like factor 11	transcription from RNA polymerase II promoter	Biological process	9748269
ZNF575	284346	zinc finger protein 575	nucleus	Cellular component	-
FOXJ2	55810	forkhead box J2	protein binding	Molecular function	25416956
RRP9	9136	ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)	poly(A) RNA binding	Molecular function	22658674
PIP4K2A	5305	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	nucleus	Cellular component	-
TJP1	7082	tight junction protein 1	cytosol	Cellular component	-
POLA1	5422	polymerase (DNA directed), alpha 1, catalytic subunit	cell proliferation	Biological process	3359994
TERF1	7013	telomeric repeat binding factor (NIMA-interacting) 1	response to drug	Biological process	-
EIF2AK1	27102	eukaryotic translation initiation factor 2-alpha kinase 1	heme binding	Molecular function	-
SWAP70	23075	SWAP switching B-cell complex 70kDa subunit	plasma membrane	Cellular component	-
PBLD	64081	phenazine biosynthesis-like protein domain containing	biosynthetic process	Biological process	-
PTPRA	5786	protein tyrosine phosphatase, receptor type, A	insulin receptor signaling pathway	Biological process	-
GRHPR	9380	glyoxylate reductase/hydroxypyruvate reductase	glycerate dehydrogenase activity	Molecular function	10484776
PCLO	27445	piccolo presynaptic cytomatrix protein	cytoskeleton organization	Biological process	-
REPIN1	29803	replication initiator 1	nuclear membrane	Cellular component	-
TMEFF1	8577	transmembrane protein with EGF-like and two follistatin-like domains 1	multicellular organismal development	Biological process	-
OPRK1	4986	opioid receptor, kappa 1	neuron projection	Cellular component	-
ATP2C1	27032	ATPase, Ca++ transporting, type 2C, member 1	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	Biological process	14632182
NKX6-1	4825	NK6 homeobox 1	response to nicotine	Biological process	-
RBBP4	5928	retinoblastoma binding protein 4	ESC/E(Z) complex	Cellular component	20075857
RAB28	9364	RAB28, member RAS oncogene family	cytoplasm	Cellular component	-
TOPORS	10210	topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase	protein binding	Molecular function	11842245
PRPF31	26121	pre-mRNA processing factor 31	nucleus	Cellular component	-
LMBRD1	55788	LMBR1 domain containing 1	insulin receptor binding	Molecular function	-
VPS72	6944	vacuolar protein sorting 72 homolog (S. cerevisiae)	negative regulation of transcription from RNA polymerase II promoter	Biological process	7702631
UBA52	7311	ubiquitin A-52 residue ribosomal protein fusion product 1	intracellular transport of virus	Biological process	-
SLC8A1	6546	solute carrier family 8 (sodium/calcium exchanger), member 1	basolateral plasma membrane	Cellular component	-
IGDCC4	57722	immunoglobulin superfamily, DCC subclass, member 4	integral component of membrane	Cellular component	-
TUBA4A	7277	tubulin, alpha 4a	mitotic cell cycle	Biological process	-
FLNB	2317	filamin B, beta	stress fiber	Cellular component	-
NFASC	23114	neurofascin	paranodal junction assembly	Biological process	-
FTL	2512	ferritin, light polypeptide	transmembrane transport	Biological process	-
AP1G2	8906	adaptor-related protein complex 1, gamma 2 subunit	viral process	Biological process	-
HMGCS2	3158	3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)	cellular ketone body metabolic process	Biological process	-
CARD14	79092	caspase recruitment domain family, member 14	plasma membrane	Cellular component	11278692
PSMB7	5695	proteasome (prosome, macropain) subunit, beta type, 7	positive regulation of protein targeting to mitochondrion	Biological process	24270810
MS4A12	54860	membrane-spanning 4-domains, subfamily A, member 12	protein binding	Molecular function	25416956
OR6M1	390261	olfactory receptor, family 6, subfamily M, member 1	plasma membrane	Cellular component	-
TRAF6	7189	TNF receptor-associated factor 6, E3 ubiquitin protein ligase	positive regulation of sequence-specific DNA binding transcription factor activity	Biological process	12296995
CRTC2	200186	CREB regulated transcription coactivator 2	positive regulation of CREB transcription factor activity	Biological process	-
CLEC1A	51267	C-type lectin domain family 1, member A	transmembrane signaling receptor activity	Molecular function	10671229
SCML2	10389	sex comb on midleg-like 2 (Drosophila)	anatomical structure morphogenesis	Biological process	10331946
HNRNPU	3192	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	gene expression	Biological process	-
TRIB2	28951	tribbles pseudokinase 2	negative regulation of protein kinase activity	Biological process	12791994
GRM5	2915	glutamate receptor, metabotropic 5	extracellular exosome	Cellular component	23376485
JAK1	3716	Janus kinase 1	regulation of cell proliferation	Biological process	-
PAFAH1B1	5048	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	nuclear envelope	Cellular component	11940666
MUC21	394263	mucin 21, cell surface associated	post-translational protein modification	Biological process	-
KCNE1	3753	potassium channel, voltage gated subfamily E regulatory beta subunit 1	sensory perception of sound	Biological process	9020846
PFN1	5216	profilin 1	nucleus	Cellular component	24700464
MOG	4340	myelin oligodendrocyte glycoprotein	cell adhesion	Biological process	-
SMAD1	4086	SMAD family member 1	response to drug	Biological process	-
LPA	4018	lipoprotein, Lp(a)	serine-type endopeptidase activity	Molecular function	2531657
RPS18	6222	ribosomal protein S18	poly(A) RNA binding	Molecular function	22658674
IL6	3569	interleukin 6	positive regulation of STAT protein import into nucleus	Biological process	17324931
CSNK1D	1453	casein kinase 1, delta	tau-protein kinase activity	Molecular function	-
LALBA	3906	lactalbumin, alpha-	signal transduction	Biological process	7644538
PIP5K1B	8395	phosphatidylinositol-4-phosphate 5-kinase, type I, beta	phospholipid metabolic process	Biological process	-
SCML2	10389	sex comb on midleg-like 2 (Drosophila)	nucleus	Cellular component	21282530
ERO1LB	56605	ERO1-like beta (S. cerevisiae)	4-hydroxyproline metabolic process	Biological process	-
NEUROG3	50674	neurogenin 3	core promoter binding	Molecular function	-
BLM	641	Bloom syndrome, RecQ helicase-like	double-strand break repair via homologous recombination	Biological process	11309417
UBL5	59286	ubiquitin-like 5	positive regulation of protein targeting to mitochondrion	Biological process	24270810
TAB1	10454	TGF-beta activated kinase 1/MAP3K7 binding protein 1	heart morphogenesis	Biological process	-
NTHL1	4913	nth endonuclease III-like 1 (E. coli)	protein binding	Molecular function	15358233
PLA2G1B	5319	phospholipase A2, group IB (pancreas)	arachidonic acid secretion	Biological process	12423354
BCAS3	54828	breast carcinoma amplified sequence 3	chromatin binding	Molecular function	17505058
PINK1	65018	PTEN induced putative kinase 1	cellular response to hypoxia	Biological process	24553947
IL1B	3553	interleukin 1, beta	extracellular space	Cellular component	3493774
STAP1	26228	signal transducing adaptor family member 1	positive regulation of gene expression	Biological process	-
IDI2	91734	isopentenyl-diphosphate delta isomerase 2	cytosol	Cellular component	-
TMPRSS12	283471	transmembrane (C-terminal) protease, serine 12	proteolysis	Biological process	-
OR51V1	283111	olfactory receptor, family 51, subfamily V, member 1	sensory perception of smell	Biological process	11121057
IKZF5	64376	IKAROS family zinc finger 5 (Pegasus)	transcription, DNA-templated	Biological process	-
VCX2	51480	variable charge, X-linked 2	cellular_component	Cellular component	-
CRYAB	1410	crystallin, alpha B	protein homooligomerization	Biological process	16303126
SOD1	6647	superoxide dismutase 1, soluble	retrograde axon cargo transport	Biological process	20510358
CXCR1	3577	chemokine (C-X-C motif) receptor 1	chemokine-mediated signaling pathway	Biological process	1840701
DRD3	1814	dopamine receptor D3	dopamine neurotransmitter receptor activity, coupled via Gi/Go	Molecular function	-
ZBTB18	10472	zinc finger and BTB domain containing 18	skeletal muscle tissue development	Biological process	-
YWHAH	7533	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta	membrane depolarization during action potential	Biological process	16728661
HBE1	3046	hemoglobin, epsilon 1	hemoglobin complex	Cellular component	-
TST	7263	thiosulfate sulfurtransferase (rhodanese)	rRNA import into mitochondrion	Biological process	20663881
BCL2	596	B-cell CLL/lymphoma 2	negative regulation of cell migration	Biological process	-
SOD1	6647	superoxide dismutase 1, soluble	response to heat	Biological process	-
CACNA1F	778	calcium channel, voltage-dependent, L type, alpha 1F subunit	axonogenesis	Biological process	-
CCNA2	890	cyclin A2	male pronucleus	Cellular component	-
ERAP1	51752	endoplasmic reticulum aminopeptidase 1	antigen processing and presentation of endogenous peptide antigen via MHC class I	Biological process	15691326
BCAR3	8412	breast cancer anti-estrogen resistance 3	guanyl-nucleotide exchange factor activity	Molecular function	-
NEIL2	252969	nei endonuclease VIII-like 2 (E. coli)	damaged DNA binding	Molecular function	-
HECTD2	143279	HECT domain containing E3 ubiquitin protein ligase 2	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	-
NOX4	50507	NADPH oxidase 4	oxygen sensor activity	Molecular function	10869423
HMGB2	3148	high mobility group box 2	nucleoplasm	Cellular component	-
NAIP	4671	NLR family, apoptosis inhibitory protein	protein binding	Molecular function	21371431
INHBA	3624	inhibin, beta A	mesodermal cell differentiation	Biological process	-
NBPF3	84224	neuroblastoma breakpoint family, member 3	cytoplasm	Cellular component	-
PREPL	9581	prolyl endopeptidase-like	cytosol	Cellular component	-
RPL14	9045	ribosomal protein L14	translational elongation	Biological process	-
WNT3	7473	wingless-type MMTV integration site family, member 3	protein binding	Molecular function	18313787
KALRN	8997	kalirin, RhoGEF kinase	regulation of small GTPase mediated signal transduction	Biological process	-
CD74	972	CD74 molecule, major histocompatibility complex, class II invariant chain	activation of MAPK activity	Biological process	-
FZD5	7855	frizzled class receptor 5	embryonic axis specification	Biological process	12121999
UBE2O	63893	ubiquitin-conjugating enzyme E2O	cytoplasm	Cellular component	24703950
AGL	178	amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase	carbohydrate metabolic process	Biological process	-
MTNR1A	4543	melatonin receptor 1A	protein binding	Molecular function	20859254
TF	7018	transferrin	extracellular space	Cellular component	16502470
OR13H1	347468	olfactory receptor, family 13, subfamily H, member 1	integral component of membrane	Cellular component	-
NRG3	10718	neuregulin 3	intracellular	Cellular component	-
STEAP2	261729	STEAP family member 2, metalloreductase	regulated secretory pathway	Biological process	12095985
RXRB	6257	retinoid X receptor, beta	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	12767074
USP17L5	728386	ubiquitin specific peptidase 17-like family member 5	cysteine-type endopeptidase activity	Molecular function	-
MEX3A	92312	mex-3 RNA binding family member A	zinc ion binding	Molecular function	-
HDAC8	55869	histone deacetylase 8	nucleoplasm	Cellular component	-
KLF4	9314	Kruppel-like factor 4 (gut)	negative regulation of protein kinase B signaling	Biological process	-
TELO2	9894	telomere maintenance 2	protein binding	Molecular function	18160036
SHANK1	50944	SH3 and multiple ankyrin repeat domains 1	protein complex binding	Molecular function	-
AGO2	27161	argonaute RISC catalytic component 2	negative regulation of translational initiation	Biological process	17524464
ABCG1	9619	ATP-binding cassette, sub-family G (WHITE), member 1	protein heterodimerization activity	Molecular function	16870176
GABRR2	2570	gamma-aminobutyric acid (GABA) A receptor, rho 2	visual perception	Biological process	-
FOXL2	668	forkhead box L2	embryonic eye morphogenesis	Biological process	-
ASCL1	429	achaete-scute family bHLH transcription factor 1	vestibular nucleus development	Biological process	-
CLEC10A	10462	C-type lectin domain family 10, member A	plasma membrane	Cellular component	8598452
RHOJ	57381	ras homolog family member J	regulation of cell shape	Biological process	-
ZER1	10444	zyg-11 related, cell cycle regulator	regulation of ubiquitin-protein transferase activity	Biological process	17304241
STK35	140901	serine/threonine kinase 35	protein serine/threonine kinase activity	Molecular function	-
PGF	5228	placental growth factor	positive regulation of cell proliferation	Biological process	21215706
ZNF385C	201181	zinc finger protein 385C	nucleic acid binding	Molecular function	-
ASIC4	55515	acid sensing (proton gated) ion channel family member 4	sodium ion transmembrane transporter activity	Molecular function	10852210
MX2	4600	MX dynamin-like GTPase 2	protein binding	Molecular function	25416956
ITIH4	3700	inter-alpha-trypsin inhibitor heavy chain family, member 4	endopeptidase inhibitor activity	Molecular function	9756925
CPQ	10404	carboxypeptidase Q	thyroid hormone generation	Biological process	-
OR6Q1	219952	olfactory receptor, family 6, subfamily Q, member 1 (gene/pseudogene)	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
SPATA7	55812	spermatogenesis associated 7	photoreceptor cell maintenance	Biological process	-
FAM98B	283742	family with sequence similarity 98, member B	cytoplasm	Cellular component	24608264
DLG2	1740	discs, large homolog 2 (Drosophila)	juxtaparanode region of axon	Cellular component	-
GNE	10020	glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase	UDP-N-acetylglucosamine 2-epimerase activity	Molecular function	-
TAPBPL	55080	TAP binding protein-like	plasma membrane	Cellular component	-
ACTR3	10096	ARP3 actin-related protein 3 homolog (yeast)	Arp2/3 protein complex	Cellular component	9230079
MBP	4155	myelin basic protein	response to toxic substance	Biological process	-
SOD1	6647	superoxide dismutase 1, soluble	mitochondrion	Cellular component	16790527
ATP6V0D2	245972	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2	hydrogen ion transmembrane transporter activity	Molecular function	-
SUFU	51684	suppressor of fused homolog (Drosophila)	skeletal system development	Biological process	10559945
IL21	59067	interleukin 21	positive regulation of B cell proliferation	Biological process	17673207
ANP32A	8125	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	intracellular signal transduction	Biological process	8192856
CCL3L1	6349	chemokine (C-C motif) ligand 3-like 1	cell chemotaxis	Biological process	-
ADRA1B	147	adrenoceptor alpha 1B	positive regulation of cytosolic calcium ion concentration	Biological process	-
PINX1	54984	PIN2/TERF1 interacting, telomerase inhibitor 1	chromosome, telomeric region	Cellular component	-
MACF1	23499	microtubule-actin crosslinking factor 1	metabolic process	Biological process	-
DSG2	1829	desmoglein 2	cellular component disassembly involved in execution phase of apoptosis	Biological process	-
CNTN5	53942	contactin 5	plasma membrane	Cellular component	-
KIF4A	24137	kinesin family member 4A	spindle microtubule	Cellular component	7929562
HSP90B2P	7190	heat shock protein 90kDa beta (Grp94), member 2, pseudogene	ATP binding	Molecular function	-
NR4A1	3164	nuclear receptor subfamily 4, group A, member 1	cell migration involved in sprouting angiogenesis	Biological process	18059339
PARD6G	84552	par-6 family cell polarity regulator gamma	bicellular tight junction assembly	Biological process	-
ALDOC	230	aldolase C, fructose-bisphosphate	cytosol	Cellular component	-
PARP12	64761	poly (ADP-ribose) polymerase family, member 12	NAD+ ADP-ribosyltransferase activity	Molecular function	-
RGS19	10287	regulator of G-protein signaling 19	brush border	Cellular component	-
KCNE2	9992	potassium channel, voltage gated subfamily E regulatory beta subunit 2	aging	Biological process	-
ADSS	159	adenylosuccinate synthase	adenylosuccinate synthase activity	Molecular function	1592113
LILRB1	10859	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	negative regulation of interferon-gamma biosynthetic process	Biological process	18684926
ANKRD27	84079	ankyrin repeat domain 27 (VPS9 domain)	positive regulation of GTPase activity	Biological process	-
PSMF1	9491	proteasome (prosome, macropain) inhibitor subunit 1 (PI31)	endopeptidase inhibitor activity	Molecular function	10764772
TXNDC5	81567	thioredoxin domain containing 5 (endoplasmic reticulum)	response to endoplasmic reticulum stress	Biological process	-
WIPF1	7456	WAS/WASL interacting protein family, member 1	actin polymerization or depolymerization	Biological process	-
MAPK8IP1	9479	mitogen-activated protein kinase 8 interacting protein 1	kinesin binding	Molecular function	11238452
RORC	6097	RAR-related orphan receptor C	regulation of gamma-delta T cell differentiation	Biological process	-
NCBP1	4686	nuclear cap binding protein subunit 1, 80kDa	termination of RNA polymerase II transcription	Biological process	-
HMGA2	8091	high mobility group AT-hook 2	DNA binding	Molecular function	8198613
PSMD8	5714	proteasome (prosome, macropain) 26S subunit, non-ATPase, 8	negative regulation of canonical Wnt signaling pathway	Biological process	-
A1CF	29974	APOBEC1 complementation factor	mRNA processing	Biological process	-
PRRC2A	7916	proline-rich coiled-coil 2A	poly(A) RNA binding	Molecular function	22658674
FERMT1	55612	fermitin family member 1	keratinocyte migration	Biological process	17012746
RPS15A	6210	ribosomal protein S15a	structural constituent of ribosome	Molecular function	9582194
GRHL1	29841	grainyhead-like 1 (Drosophila)	small molecule metabolic process	Biological process	-
PAX5	5079	paired box 5	organ morphogenesis	Biological process	10524622
GTPBP4	23560	GTP binding protein 4	negative regulation of cell-cell adhesion	Biological process	17210637
GTF2B	2959	general transcription factor IIB	gene expression	Biological process	-
MT3	4504	metallothionein 3	synaptic vesicle	Cellular component	-
ARSB	411	arylsulfatase B	mitochondrion	Cellular component	-
JAK2	3717	Janus kinase 2	nucleus	Cellular component	10502458
UBA52	7311	ubiquitin A-52 residue ribosomal protein fusion product 1	membrane organization	Biological process	-
CKMT1B	1159	creatine kinase, mitochondrial 1B	extracellular exosome	Cellular component	23376485
CCDC151	115948	coiled-coil domain containing 151	ciliary basal body	Cellular component	-
MED4	29079	mediator complex subunit 4	intracellular steroid hormone receptor signaling pathway	Biological process	11867769
RP1L1	94137	retinitis pigmentosa 1-like 1	microtubule	Cellular component	-
TRIM5	85363	tripartite motif containing 5	protein K63-linked ubiquitination	Biological process	21512573
MYH3	4621	myosin, heavy chain 3, skeletal muscle, embryonic	embryonic limb morphogenesis	Biological process	16642020
TRIM31	11074	tripartite motif containing 31	positive regulation of sequence-specific DNA binding transcription factor activity	Biological process	23077300
KRT34	3885	keratin 34, type I	extracellular exosome	Cellular component	23376485
CDH17	1015	cadherin 17, LI cadherin (liver-intestine)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	Biological process	-
PEX16	9409	peroxisomal biogenesis factor 16	integral component of peroxisomal membrane	Cellular component	9922452
DSC3	1825	desmocollin 3	cytoplasm	Cellular component	-
CTBP2	1488	C-terminal binding protein 2	NAD binding	Molecular function	-
KCNA4	3739	potassium channel, voltage gated shaker related subfamily A, member 4	voltage-gated potassium channel complex	Cellular component	-
ACY3	91703	aminoacylase 3	molecular_function	Molecular function	-
RAB39B	116442	RAB39B, member RAS oncogene family	vesicle	Cellular component	24006491
AXIN2	8313	axin 2	intramembranous ossification	Biological process	-
KNTC1	9735	kinetochore associated 1	plasma membrane	Cellular component	-
JUND	3727	jun D proto-oncogene	response to light stimulus	Biological process	-
CSRP1	1465	cysteine and glycine-rich protein 1	zinc ion binding	Molecular function	-
TUFT1	7286	tuftelin 1	extracellular region	Cellular component	12489194
GLIS1	148979	GLIS family zinc finger 1	metal ion binding	Molecular function	-
PLA2G4E	123745	phospholipase A2, group IVE	metal ion binding	Molecular function	-
BRCA1	672	breast cancer 1, early onset	protein ubiquitination	Biological process	17349954
TAF8	129685	TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa	transcription factor TFIID complex	Cellular component	14580349
DHRS1	115817	dehydrogenase/reductase (SDR family) member 1	oxidoreductase activity	Molecular function	-
GREM1	26585	gremlin 1, DAN family BMP antagonist	positive regulation of transcription from RNA polymerase II promoter	Biological process	9660951
FURIN	5045	furin (paired basic amino acid cleaving enzyme)	trans-Golgi network	Cellular component	14744861
LAMA5	3911	laminin, alpha 5	extracellular matrix disassembly	Biological process	-
FASLG	356	Fas ligand (TNF superfamily, member 6)	positive regulation of endothelial cell apoptotic process	Biological process	18835034
CCNB1	891	cyclin B1	mitotic metaphase plate congression	Biological process	18195732
PIWIL1	9271	piwi-like RNA-mediated gene silencing 1	single-stranded RNA binding	Molecular function	-
PRMT5	10419	protein arginine methyltransferase 5	gene expression	Biological process	-
FLOT1	10211	flotillin 1	centriolar satellite	Cellular component	18000879
GNAI3	2773	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3	G-protein beta/gamma-subunit complex binding	Molecular function	-
KIF18A	81930	kinesin family member 18A	microtubule organizing center	Cellular component	-
GSTT2B	653689	glutathione S-transferase theta 2B (gene/pseudogene)	small molecule metabolic process	Biological process	-
ZGLP1	100125288	zinc finger, GATA-like protein 1	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
NLK	51701	nemo-like kinase	protein serine/threonine kinase activity	Molecular function	-
SART3	9733	squamous cell carcinoma antigen recognized by T cells 3	nucleosome assembly	Biological process	24526689
RAB7B	338382	RAB7B, member RAS oncogene family	negative regulation of toll-like receptor 9 signaling pathway	Biological process	-
ARSH	347527	arylsulfatase family, member H	small molecule metabolic process	Biological process	-
PSME4	23198	proteasome (prosome, macropain) activator subunit 4	antigen processing and presentation of exogenous peptide antigen via MHC class I	Biological process	-
HOXA13	3209	homeobox A13	embryonic forelimb morphogenesis	Biological process	-
NFIA	4774	nuclear factor I/A	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	17010934
CA12	771	carbonic anhydrase XII	integral component of membrane	Cellular component	-
SPECC1L	23384	sperm antigen with calponin homology and coiled-coil domains 1-like	cell migration	Biological process	-
GIPC1	10755	GIPC PDZ domain containing family, member 1	cell cortex	Cellular component	12857860
ABAT	18	4-aminobutyrate aminotransferase	4-aminobutyrate transaminase activity	Molecular function	-
ITPR2	3709	inositol 1,4,5-trisphosphate receptor, type 2	calcium ion transmembrane transport	Biological process	-
SNPH	9751	syntaphilin	integral component of membrane	Cellular component	-
CFHR1	3078	complement factor H-related 1	extracellular space	Cellular component	1711047
FBXO7	25793	F-box protein 7	regulation of protein stability	Biological process	15145941
PAX4	5078	paired box 4	positive regulation of cell differentiation	Biological process	-
TEX2	55852	testis expressed 2	molecular_function	Molecular function	-
FLOT1	10211	flotillin 1	positive regulation of interferon-beta production	Biological process	25204797
GFAP	2670	glial fibrillary acidic protein	protein binding	Molecular function	16189514
SERPINB8	5271	serpin peptidase inhibitor, clade B (ovalbumin), member 8	extracellular space	Cellular component	-
TGIF2LY	90655	TGFB-induced factor homeobox 2-like, Y-linked	protein binding	Molecular function	25416956
EPO	2056	erythropoietin	extracellular space	Cellular component	14569084
CNTN2	6900	contactin 2 (axonal)	protein self-association	Molecular function	-
ULK3	25989	unc-51 like kinase 3	ciliary tip	Cellular component	-
ATP1A4	480	ATPase, Na+/K+ transporting, alpha 4 polypeptide	transmembrane transport	Biological process	-
METTL2B	55798	methyltransferase like 2B	tRNA (cytosine) methyltransferase activity	Molecular function	21518805
PRSS48	345062	protease, serine, 48	serine-type endopeptidase activity	Molecular function	-
MYO1B	4430	myosin IB	cell periphery	Cellular component	-
VCAM1	7412	vascular cell adhesion molecule 1	interferon-gamma-mediated signaling pathway	Biological process	-
KIF2C	11004	kinesin family member 2C	kinetochore	Cellular component	14960279
PELO	53918	pelota homolog (Drosophila)	cytoplasm	Cellular component	-
CANX	821	calnexin	extracellular exosome	Cellular component	21235781
RPP30	10556	ribonuclease P/MRP 30kDa subunit	RNA phosphodiester bond hydrolysis	Biological process	9630247
CA2	760	carbonic anhydrase II	axon	Cellular component	-
SETX	23064	senataxin	cellular response to DNA damage stimulus	Biological process	17562789
ITGB1	3688	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	ruffle membrane	Cellular component	10455171
HMGB3	3149	high mobility group box 3	double-stranded DNA binding	Molecular function	-
ACBD3	64746	acyl-CoA binding domain containing 3	Golgi apparatus	Cellular component	-
GGT2	728441	gamma-glutamyltransferase 2	gamma-glutamyltransferase activity	Molecular function	18357469
ACOT4	122970	acyl-CoA thioesterase 4	dicarboxylic acid catabolic process	Biological process	16141203
GMNN	51053	geminin, DNA replication inhibitor	cytoplasm	Cellular component	-
LPL	4023	lipoprotein lipase	extracellular region	Cellular component	-
INPP5E	56623	inositol polyphosphate-5-phosphatase, 72 kDa	cytosol	Cellular component	-
CREBBP	1387	CREB binding protein	protein complex assembly	Biological process	7913207
TRPV4	59341	transient receptor potential cation channel, subfamily V, member 4	cytosol	Cellular component	-
NEUROD2	4761	neuronal differentiation 2	protein heterodimerization activity	Molecular function	-
RCOR2	283248	REST corepressor 2	chromatin binding	Molecular function	-
SLC39A4	55630	solute carrier family 39 (zinc transporter), member 4	cellular zinc ion homeostasis	Biological process	-
AKT2	208	v-akt murine thymoma viral oncogene homolog 2	positive regulation of protein targeting to membrane	Biological process	-
LDB1	8861	LIM domain binding 1	neuron differentiation	Biological process	-
HS3ST5	222537	heparan sulfate (glucosamine) 3-O-sulfotransferase 5	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity	Molecular function	12138164
OLR1	4973	oxidized low density lipoprotein (lectin-like) receptor 1	intracellular membrane-bounded organelle	Cellular component	-
EPGN	255324	epithelial mitogen	angiogenesis	Biological process	15611079
DMD	1756	dystrophin	cardiac muscle contraction	Biological process	19027585
DLX2	1746	distal-less homeobox 2	proximal/distal pattern formation	Biological process	-
LYRM4	57128	LYR motif containing 4	small molecule metabolic process	Biological process	-
PMAIP1	5366	phorbol-12-myristate-13-acetate-induced protein 1	positive regulation of protein oligomerization	Biological process	17024184
PNPLA2	57104	patatin-like phospholipase domain containing 2	endoplasmic reticulum membrane	Cellular component	-
TCTEX1D1	200132	Tctex1 domain containing 1	protein binding	Molecular function	25416956
SLC10A3	8273	solute carrier family 10, member 3	bile acid:sodium symporter activity	Molecular function	-
SLC7A14	57709	solute carrier family 7, member 14	antiporter activity	Molecular function	-
MYO15A	51168	myosin XVA	motor activity	Molecular function	-
FHIT	2272	fragile histidine triad	hydrolase activity	Molecular function	8794732
B2M	567	beta-2-microglobulin	Golgi membrane	Cellular component	-
SEC24D	9871	SEC24 family member D	ER to Golgi transport vesicle membrane	Cellular component	-
SUN5	140732	Sad1 and UNC84 domain containing 5	cellular_component	Cellular component	-
PAFAH2	5051	platelet-activating factor acetylhydrolase 2, 40kDa	phospholipid binding	Molecular function	8955149
FGF18	8817	fibroblast growth factor 18	growth factor activity	Molecular function	-
ICAM1	3383	intercellular adhesion molecule 1	external side of plasma membrane	Cellular component	-
PDE3B	5140	phosphodiesterase 3B, cGMP-inhibited	insulin receptor signaling pathway	Biological process	-
P2RX4	5025	purinergic receptor P2X, ligand gated ion channel, 4	ion transmembrane transport	Biological process	10515189
RPS27A	6233	ribosomal protein S27a	TRIF-dependent toll-like receptor signaling pathway	Biological process	-
PRMT2	3275	protein arginine methyltransferase 2	negative regulation of G1/S transition of mitotic cell cycle	Biological process	-
TAB2	23118	TGF-beta activated kinase 1/MAP3K7 binding protein 2	cytosol	Cellular component	-
LAMA5	3911	laminin, alpha 5	lung development	Biological process	-
GDI2	2665	GDP dissociation inhibitor 2	small GTPase binding	Molecular function	-
THBS1	7057	thrombospondin 1	cell surface	Cellular component	2435757
AKT1	207	v-akt murine thymoma viral oncogene homolog 1	response to fluid shear stress	Biological process	10376603
TMPRSS11B	132724	transmembrane protease, serine 11B	plasma membrane	Cellular component	24498351
BAG3	9531	BCL2-associated athanogene 3	protein complex binding	Molecular function	-
CDC37	11140	cell division cycle 37	Hsp90 protein binding	Molecular function	-
SPR	6697	sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)	extracellular exosome	Cellular component	19056867
CX3CR1	1524	chemokine (C-X3-C motif) receptor 1	viral process	Biological process	-
TRRAP	8295	transformation/transcription domain-associated protein	histone H2A acetylation	Biological process	14966270
GAS6	2621	growth arrest-specific 6	protein phosphorylation	Biological process	16359517
CORO1A	11151	coronin, actin binding protein, 1A	actin filament binding	Molecular function	22364218
PCK1	5105	phosphoenolpyruvate carboxykinase 1 (soluble)	internal protein amino acid acetylation	Biological process	20167786
CUBN	8029	cubilin (intrinsic factor-cobalamin receptor)	Golgi apparatus	Cellular component	-
CTR9	9646	CTR9, Paf1/RNA polymerase II complex component	positive regulation of histone H3-K4 methylation	Biological process	16024656
P2RX1	5023	purinergic receptor P2X, ligand gated ion channel, 1	insemination	Biological process	-
PLEKHA1	59338	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	protein binding	Molecular function	11802782
RAB3A	5864	RAB3A, member RAS oncogene family	regulation of synaptic vesicle fusion to presynaptic membrane	Biological process	-
MRPL18	29074	mitochondrial ribosomal protein L18	extracellular space	Cellular component	22664934
CSNK1E	1454	casein kinase 1, epsilon	endocytosis	Biological process	-
PTCH1	5727	patched 1	axonal growth cone	Cellular component	-
SLC12A2	6558	solute carrier family 12 (sodium/potassium/chloride transporter), member 2	multicellular organism growth	Biological process	-
PAX6	5080	paired box 6	nucleus	Cellular component	17291498
BAD	572	BCL2-associated agonist of cell death	response to calcium ion	Biological process	-
ESM1	11082	endothelial cell-specific molecule 1	angiogenesis	Biological process	11866539
AQP3	360	aquaporin 3 (Gill blood group)	positive regulation of immune system process	Biological process	17943189
SP3	6670	Sp3 transcription factor	transcription from RNA polymerase II promoter	Biological process	-
GHRL	51738	ghrelin/obestatin prepropeptide	cellular protein metabolic process	Biological process	-
RBCK1	10616	RanBP-type and C3HC4-type zinc finger containing 1	protein binding	Molecular function	16083853
GRIN2A	2903	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	N-methyl-D-aspartate selective glutamate receptor complex	Cellular component	10480938
ACAP2	23527	ArfGAP with coiled-coil, ankyrin repeat and PH domains 2	metal ion binding	Molecular function	-
BMP3	651	bone morphogenetic protein 3	growth	Biological process	-
UTS2	10911	urotensin 2	positive regulation of collagen biosynthetic process	Biological process	-
ELOVL6	79071	ELOVL fatty acid elongase 6	integral component of endoplasmic reticulum membrane	Cellular component	-
CCL18	6362	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	extracellular space	Cellular component	-
ADARB1	104	adenosine deaminase, RNA-specific, B1	positive regulation of viral genome replication	Biological process	21289159
TGM3	7053	transglutaminase 3	calcium ion binding	Molecular function	12679341
FASLG	356	Fas ligand (TNF superfamily, member 6)	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Biological process	-
ZNF736	728927	zinc finger protein 736	DNA binding	Molecular function	-
PSMD1	5707	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	programmed cell death	Biological process	-
ELL	8178	elongation factor RNA polymerase II	gene expression	Biological process	-
SYNGR3	9143	synaptogyrin 3	protein N-terminus binding	Molecular function	-
HIST1H3E	8353	histone cluster 1, H3e	gene expression	Biological process	-
DDX1	1653	DEAD (Asp-Glu-Ala-Asp) box helicase 1	DNA/RNA helicase activity	Molecular function	18710941
RPL23	9349	ribosomal protein L23	translational elongation	Biological process	-
PRODH2	58510	proline dehydrogenase (oxidase) 2	oxidation-reduction process	Biological process	-
SF3A2	8175	splicing factor 3a, subunit 2, 66kDa	gene expression	Biological process	-
ABHD10	55347	abhydrolase domain containing 10	glucuronoside catabolic process	Biological process	22294686
RAPGEF3	10411	Rap guanine nucleotide exchange factor (GEF) 3	cellular response to cAMP	Biological process	21840392
ATOH1	474	atonal homolog 1 (Drosophila)	transcription from RNA polymerase II promoter	Biological process	8872459
DCTPP1	79077	dCTP pyrophosphatase 1	cytosol	Cellular component	-
NOTCH4	4855	notch 4	Notch receptor processing	Biological process	-
MTOR	2475	mechanistic target of rapamycin (serine/threonine kinase)	PML body	Cellular component	-
PAX7	5081	paired box 7	regulation of cell fate commitment	Biological process	-
CASP9	842	caspase 9, apoptosis-related cysteine peptidase	extrinsic apoptotic signaling pathway	Biological process	-
FNDC1	84624	fibronectin type III domain containing 1	positive regulation of protein phosphorylation	Biological process	-
DDX11	1663	DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11	nuclear chromatin	Cellular component	17105772
SLC16A8	23539	solute carrier family 16 (monocarboxylate transporter), member 8	cellular metabolic process	Biological process	-
USP6NL	9712	USP6 N-terminal like	regulation of cilium assembly	Biological process	17646400
ACE	1636	angiotensin I converting enzyme	antigen processing and presentation of peptide antigen via MHC class I	Biological process	23257181
UBA3	9039	ubiquitin-like modifier activating enzyme 3	protein neddylation	Biological process	-
STYK1	55359	serine/threonine/tyrosine kinase 1	cell differentiation	Biological process	-
ATP2B4	493	ATPase, Ca++ transporting, plasma membrane 4	protein binding	Molecular function	11274188
NEUROG3	50674	neurogenin 3	transcription, DNA-templated	Biological process	-
NF2	4771	neurofibromin 2 (merlin)	cell-cell junction organization	Biological process	-
IL20	50604	interleukin 20	inflammatory response	Biological process	-
SLC17A3	10786	solute carrier family 17 (organic anion transporter), member 3	toxin transporter activity	Molecular function	20810651
SLC39A14	23516	solute carrier family 39 (zinc transporter), member 14	cellular zinc ion homeostasis	Biological process	15642354
PLSCR1	5359	phospholipid scramblase 1	integral component of plasma membrane	Cellular component	12586838
OR2A4	79541	olfactory receptor, family 2, subfamily A, member 4	G-protein coupled receptor signaling pathway	Biological process	-
MYO1C	4641	myosin IC	lateral plasma membrane	Cellular component	9858156
CEBPZ	10153	CCAAT/enhancer binding protein (C/EBP), zeta	transcription from RNA polymerase II promoter	Biological process	2247079
MMP13	4322	matrix metallopeptidase 13	endochondral ossification	Biological process	-
BOLL	66037	boule-like RNA-binding protein	positive regulation of translational initiation	Biological process	16001084
OR4D2	124538	olfactory receptor, family 4, subfamily D, member 2	olfactory receptor activity	Molecular function	-
FYN	2534	FYN proto-oncogene, Src family tyrosine kinase	ion channel binding	Molecular function	-
OR5AC1	81431	olfactory receptor, family 5, subfamily AC, member 1 (gene/pseudogene)	plasma membrane	Cellular component	-
ICK	22858	intestinal cell (MAK-like) kinase	intraciliary transport	Biological process	-
NLGN2	57555	neuroligin 2	positive regulation of protein localization to synapse	Biological process	24613359
HYAL1	3373	hyaluronoglucosaminidase 1	small molecule metabolic process	Biological process	-
TSSK4	283629	testis-specific serine kinase 4	cytoplasm	Cellular component	-
DAB1	1600	Dab, reelin signal transducer, homolog 1 (Drosophila)	brush border	Cellular component	-
ALX1	8092	ALX homeobox 1	mesenchymal cell development	Biological process	-
SLC2A3	6515	solute carrier family 2 (facilitated glucose transporter), member 3	carbohydrate metabolic process	Biological process	-
UBE2L3	7332	ubiquitin-conjugating enzyme E2L 3	ligase activity	Molecular function	-
RAD51AP1	10635	RAD51 associated protein 1	nucleus	Cellular component	9396801
PTH1R	5745	parathyroid hormone 1 receptor	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	Biological process	9927325
CYP20A1	57404	cytochrome P450, family 20, subfamily A, polypeptide 1	iron ion binding	Molecular function	-
GNG12	55970	guanine nucleotide binding protein (G protein), gamma 12	response to lipopolysaccharide	Biological process	-
PAFAH1B1	5048	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	cerebral cortex development	Biological process	9063735
ZNF705F	790969	zinc finger protein 705F	regulation of transcription, DNA-templated	Biological process	-
DUSP6	1848	dual specificity phosphatase 6	dorsal/ventral pattern formation	Biological process	-
CSN2	1447	casein beta	negative regulation of lactation	Biological process	-
PRDM15	63977	PR domain containing 15	methyltransferase activity	Molecular function	-
CNEP1R1	255919	CTD nuclear envelope phosphatase 1 regulatory subunit 1	lipid metabolic process	Biological process	-
PTCH2	8643	patched 2	hedgehog receptor activity	Molecular function	11001584
RGS19	10287	regulator of G-protein signaling 19	Golgi apparatus	Cellular component	9571244
IL19	29949	interleukin 19	cytokine activity	Molecular function	11196675
CABP2	51475	calcium binding protein 2	Golgi apparatus	Cellular component	19338761
TPH1	7166	tryptophan hydroxylase 1	iron ion binding	Molecular function	-
SNX24	28966	sorting nexin 24	protein transport	Biological process	-
IGKV1D-33	28896	immunoglobulin kappa variable 1D-33	blood microparticle	Cellular component	22516433
PLCB1	23236	phospholipase C, beta 1 (phosphoinositide-specific)	glutamate receptor signaling pathway	Biological process	-
POLR3F	10621	polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa	defense response to virus	Biological process	-
TBC1D22B	55633	TBC1 domain family, member 22B	positive regulation of GTPase activity	Biological process	-
HLA-E	3133	major histocompatibility complex, class I, E	positive regulation of TRAIL production	Biological process	25631937
DCC	1630	DCC netrin 1 receptor	negative regulation of neuron projection development	Biological process	19616629
PDCD5	9141	programmed cell death 5	negative regulation of cell proliferation	Biological process	16374546
ATP5E	514	ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit	mitochondrial proton-transporting ATP synthase complex	Cellular component	12110673
CEP162	22832	centrosomal protein 162kDa	cytoplasm	Cellular component	-
TCTN2	79867	tectonic family member 2	smoothened signaling pathway	Biological process	-
PDGFB	5155	platelet-derived growth factor beta polypeptide	epidermal growth factor receptor signaling pathway	Biological process	-
CDKL4	344387	cyclin-dependent kinase-like 4	ATP binding	Molecular function	-
BMPR1B	658	bone morphogenetic protein receptor, type IB	cartilage condensation	Biological process	14523231
KITLG	4254	KIT ligand	ectopic germ cell programmed cell death	Biological process	-
CAPNS2	84290	calpain, small subunit 2	calcium-dependent cysteine-type endopeptidase activity	Molecular function	-
NLRP3	114548	NLR family, pyrin domain containing 3	inflammatory response	Biological process	12093792
DGKH	160851	diacylglycerol kinase, eta	nucleus	Cellular component	-
TNFSF10	8743	tumor necrosis factor (ligand) superfamily, member 10	cytokine activity	Molecular function	-
SPAM1	6677	sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)	multicellular organism reproduction	Biological process	-
BRD8	10902	bromodomain containing 8	NuA4 histone acetyltransferase complex	Cellular component	14966270
DENR	8562	density-regulated protein	protein binding	Molecular function	16874301
BBS4	585	Bardet-Biedl syndrome 4	microtubule motor activity	Molecular function	15107855
CASP3	836	caspase 3, apoptosis-related cysteine peptidase	apoptotic DNA fragmentation	Biological process	-
RABGEF1	27342	RAB guanine nucleotide exchange factor (GEF) 1	endocytosis	Biological process	-
SERP1	27230	stress-associated endoplasmic reticulum protein 1	integral component of membrane	Cellular component	-
ALG5	29880	ALG5, dolichyl-phosphate beta-glucosyltransferase	dolichyl-phosphate beta-glucosyltransferase activity	Molecular function	-
F2R	2149	coagulation factor II (thrombin) receptor	positive regulation of vasoconstriction	Biological process	-
RAB6A	5870	RAB6A, member RAS oncogene family	protein localization to Golgi apparatus	Biological process	12447383
SUPT20H	55578	suppressor of Ty 20 homolog (S. cerevisiae)	protein binding	Molecular function	16751104
MYH9	4627	myosin, heavy chain 9, non-muscle	cytokinesis	Biological process	15774463
TWF1	5756	twinfilin actin-binding protein 1	negative regulation of actin filament polymerization	Biological process	12807912
STK11	6794	serine/threonine kinase 11	extracellular exosome	Cellular component	19056867
PRRC2C	23215	proline-rich coiled-coil 2C	membrane	Cellular component	19946888
UGT1A8	54576	UDP glucuronosyltransferase 1 family, polypeptide A8	flavone metabolic process	Biological process	18052087
TMEM79	84283	transmembrane protein 79	trans-Golgi network membrane	Cellular component	-
MYO5C	55930	myosin VC	myosin complex	Cellular component	-
C3orf33	285315	chromosome 3 open reading frame 33	extracellular space	Cellular component	20680465
DDX1	1653	DEAD (Asp-Glu-Ala-Asp) box helicase 1	cytoplasmic stress granule	Cellular component	18335541
TGFB1	7040	transforming growth factor, beta 1	receptor catabolic process	Biological process	17878231
ADGRL2	23266	adhesion G protein-coupled receptor L2	G-protein coupled receptor signaling pathway	Biological process	10030676
ESYT3	83850	extended synaptotagmin-like protein 3	protein binding	Molecular function	23791178
PSMB11	122706	proteasome (prosome, macropain) subunit, beta type, 11	mitotic cell cycle	Biological process	-
CDK5	1020	cyclin-dependent kinase 5	protein localization to synapse	Biological process	-
PARP14	54625	poly (ADP-ribose) polymerase family, member 14	NAD+ ADP-ribosyltransferase activity	Molecular function	-
SOD2	6648	superoxide dismutase 2, mitochondrial	detection of oxygen	Biological process	-
SLX4	84464	SLX4 structure-specific endonuclease subunit	nucleoplasm	Cellular component	-
MAPT	4137	microtubule-associated protein tau	programmed cell death	Biological process	-
SLIRP	81892	SRA stem-loop interacting RNA binding protein	single fertilization	Biological process	-
SPINT2	10653	serine peptidase inhibitor, Kunitz type, 2	extracellular region	Cellular component	9346890
PAXIP1	22976	PAX interacting (with transcription-activation domain) protein 1	positive regulation of transcription initiation from RNA polymerase II promoter	Biological process	-
CCND1	595	cyclin D1	protein binding	Molecular function	15232106
TAF5	6877	TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa	actin cytoskeleton	Cellular component	-
NAALAD2	10003	N-acetylated alpha-linked acidic dipeptidase 2	integral component of membrane	Cellular component	10085079
NPIPB11	728888	nuclear pore complex interacting protein family, member B11	integral component of membrane	Cellular component	-
TUBB4B	10383	tubulin, beta 4B class IVb	GTPase activity	Molecular function	-
TSNAX	7257	translin-associated factor X	single-stranded DNA binding	Molecular function	-
NDRG1	10397	N-myc downstream regulated 1	perinuclear region of cytoplasm	Cellular component	17786215
LANCL1	10314	LanC lantibiotic synthetase component C-like 1 (bacterial)	metabolic process	Biological process	-
CSGALNACT1	55790	chondroitin sulfate N-acetylgalactosaminyltransferase 1	chondroitin sulfate proteoglycan biosynthetic process	Biological process	11788602
CRTC2	200186	CREB regulated transcription coactivator 2	extracellular exosome	Cellular component	19056867
ASPH	444	aspartate beta-hydroxylase	calcium ion transmembrane transport	Biological process	21062895
KRTAP4-2	85291	keratin associated protein 4-2	protein binding	Molecular function	25416956
BDNF	627	brain-derived neurotrophic factor	regulation of neuron differentiation	Biological process	-
PITRM1	10531	pitrilysin metallopeptidase 1	enzyme activator activity	Molecular function	9733512
NME6	10201	NME/NM23 nucleoside diphosphate kinase 6	negative regulation of mitotic nuclear division	Biological process	10618642
CLASP1	23332	cytoplasmic linker associated protein 1	cytosol	Cellular component	-
APOC1	341	apolipoprotein C-I	regulation of cholesterol transport	Biological process	15576844
ADAM9	8754	ADAM metallopeptidase domain 9	response to hydrogen peroxide	Biological process	17018608
FBXW2	26190	F-box and WD repeat domain containing 2	protein ubiquitination	Biological process	10531035
ASIC2	40	acid sensing (proton gated) ion channel 2	positive regulation of cation channel activity	Biological process	-
TPCN1	53373	two pore segment channel 1	ion transmembrane transport	Biological process	-
DDX20	11218	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20	cytoskeleton	Cellular component	10383418
LMO2	4005	LIM domain only 2 (rhombotin-like 1)	multicellular organismal development	Biological process	1923511
RPL6	6128	ribosomal protein L6	cytosolic large ribosomal subunit	Cellular component	12962325
PHGDH	26227	phosphoglycerate dehydrogenase	NAD binding	Molecular function	-
KIAA0368	23392	KIAA0368	endoplasmic reticulum	Cellular component	15496406
AKR1E2	83592	aldo-keto reductase family 1, member E2	1,5-anhydro-D-fructose reductase activity	Molecular function	-
PICALM	8301	phosphatidylinositol binding clathrin assembly protein	synaptic vesicle maturation	Biological process	-
WNT3	7473	wingless-type MMTV integration site family, member 3	neuron differentiation	Biological process	-
HIC1	3090	hypermethylated in cancer 1	intrinsic apoptotic signaling pathway in response to DNA damage	Biological process	16269335
PPP1CB	5500	protein phosphatase 1, catalytic subunit, beta isozyme	nucleoplasm	Cellular component	-
DUOX2	50506	dual oxidase 2	integral component of membrane	Cellular component	-
PSME2	5721	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	Biological process	-
FAM120B	84498	family with sequence similarity 120B	regulation of transcription, DNA-templated	Biological process	-
PRKCA	5578	protein kinase C, alpha	angiogenesis	Biological process	-
CLIC4	25932	chloride intracellular channel 4	chloride channel activity	Molecular function	-
CASP1	834	caspase 1, apoptosis-related cysteine peptidase	NLRP3 inflammasome complex	Cellular component	15030775
EPOR	2057	erythropoietin receptor	extracellular region	Cellular component	-
TMBIM4	51643	transmembrane BAX inhibitor motif containing 4	apoptotic process	Biological process	-
ADAM10	102	ADAM metallopeptidase domain 10	protein binding	Molecular function	10527948
RARB	5915	retinoic acid receptor, beta	protein binding	Molecular function	25416956
CSF1	1435	colony stimulating factor 1 (macrophage)	developmental process involved in reproduction	Biological process	19017797
H6PD	9563	hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)	oxidation-reduction process	Biological process	-
OLFM3	118427	olfactomedin 3	extracellular space	Cellular component	-
ZNF438	220929	zinc finger protein 438	DNA binding	Molecular function	-
TNKS	8658	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase	spindle assembly	Biological process	17026964
PKLR	5313	pyruvate kinase, liver and RBC	response to ATP	Biological process	-
BRMS1L	84312	breast cancer metastasis-suppressor 1-like	Sin3-type complex	Cellular component	-
CSTF2T	23283	cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant	protein binding	Molecular function	16189514
GCM2	9247	glial cells missing homolog 2 (Drosophila)	cell differentiation	Biological process	-
TAF1L	138474	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like	transcription from RNA polymerase II promoter	Biological process	-
NUDT16	131870	nudix (nucleoside diphosphate linked moiety X)-type motif 16	cytoplasm	Cellular component	20385596
UBE2N	7334	ubiquitin-conjugating enzyme E2N	DNA double-strand break processing	Biological process	17349954
POLR1D	51082	polymerase (RNA) I polypeptide D, 16kDa	RNA polymerase III activity	Molecular function	-
DOK4	55715	docking protein 4	protein binding	Molecular function	16273093
CREBBP	1387	CREB binding protein	embryonic digit morphogenesis	Biological process	11001584
AQP7P3	441432	aquaporin 7 pseudogene 3	transport	Biological process	-
GARS	2617	glycyl-tRNA synthetase	secretory granule	Cellular component	-
SLC1A3	6507	solute carrier family 1 (glial high affinity glutamate transporter), member 3	integral component of membrane	Cellular component	-
MCM5	4174	minichromosome maintenance complex component 5	nucleus	Cellular component	8751386
PPP1R12A	4659	protein phosphatase 1, regulatory subunit 12A	signal transducer activity	Molecular function	8662509
CEP55	55165	centrosomal protein 55kDa	cleavage furrow	Cellular component	-
ZFYVE19	84936	zinc finger, FYVE domain containing 19	protein binding	Molecular function	17500595
OVOL2	58495	ovo-like zinc finger 2	regulation of keratinocyte proliferation	Biological process	19700410
ZNF35	7584	zinc finger protein 35	cell	Cellular component	-
SPOPL	339745	speckle-type POZ protein-like	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological process	22632832
CSNK1D	1453	casein kinase 1, delta	cytosol	Cellular component	-
BNIP3	664	BCL2/adenovirus E1B 19kDa interacting protein 3	mitochondrial outer membrane permeabilization	Biological process	18371312
PPP1R1B	84152	protein phosphatase 1, regulatory (inhibitor) subunit 1B	protein serine/threonine phosphatase inhibitor activity	Molecular function	-
KLC3	147700	kinesin light chain 3	protein binding	Molecular function	25416956
HRAS	3265	Harvey rat sarcoma viral oncogene homolog	positive regulation of epithelial cell proliferation	Biological process	20154697
CYP26A1	1592	cytochrome P450, family 26, subfamily A, polypeptide 1	xenobiotic metabolic process	Biological process	-
AIMP2	7965	aminoacyl tRNA synthetase complex-interacting multifunctional protein 2	tRNA aminoacylation for protein translation	Biological process	-
BMP7	655	bone morphogenetic protein 7	positive regulation of transcription, DNA-templated	Biological process	14517293
ACAP1	9744	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1	protein transport	Biological process	-
IL2RA	3559	interleukin 2 receptor, alpha	apoptotic process	Biological process	9096364
IGHE	3497	immunoglobulin heavy constant epsilon	antigen binding	Molecular function	6300763
POLB	5423	polymerase (DNA directed), beta	microtubule	Cellular component	15725623
ADAMTS3	9508	ADAM metallopeptidase with thrombospondin type 1 motif, 3	protein binding	Molecular function	24552833
LALBA	3906	lactalbumin, alpha-	Golgi membrane	Cellular component	-
DPYD	1806	dihydropyrimidine dehydrogenase	beta-alanine biosynthetic process	Biological process	-
PDPN	10630	podoplanin	cell morphogenesis	Biological process	-
NETO2	81831	neuropilin (NRP) and tolloid (TLL)-like 2	postsynaptic density	Cellular component	-
SLX4	84464	SLX4 structure-specific endonuclease subunit	nuclear chromatin	Cellular component	19596235
CCNO	10309	cyclin O	multi-ciliated epithelial cell differentiation	Biological process	24747639
CCNB1	891	cyclin B1	centrosome	Cellular component	12524548
PLA1A	51365	phospholipase A1 member A	acrosomal membrane	Cellular component	-
DUOX2	50506	dual oxidase 2	oxidation-reduction process	Biological process	10601291
PAM16	51025	presequence translocase-associated motor 16 homolog (S. cerevisiae)	presequence translocase-associated import motor	Cellular component	20053669
EEF2K	29904	eukaryotic elongation factor 2 kinase	protein autophosphorylation	Biological process	23184662
DGCR14	8220	DiGeorge syndrome critical region gene 14	nucleus	Cellular component	8703114
CBLN1	869	cerebellin 1 precursor	positive regulation of synapse assembly	Biological process	-
CHRND	1144	cholinergic receptor, nicotinic, delta (muscle)	regulation of membrane potential	Biological process	-
TGFBR3	7049	transforming growth factor, beta receptor III	response to luteinizing hormone	Biological process	14557487
ABCA1	19	ATP-binding cassette, sub-family A (ABC1), member 1	positive regulation of cholesterol efflux	Biological process	-
EXOSC5	56915	exosome component 5	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'	Biological process	-
PRDM16	63976	PR domain containing 16	protein binding	Molecular function	19049980
TOX3	27324	TOX high mobility group box family member 3	apoptotic process	Biological process	-
KIF18B	146909	kinesin family member 18B	microtubule plus-end	Cellular component	21820309
ZNF416	55659	zinc finger protein 416	metal ion binding	Molecular function	-
RPS15	6209	ribosomal protein S15	nucleus	Cellular component	2159154
PAK3	5063	p21 protein (Cdc42/Rac)-activated kinase 3	T cell receptor signaling pathway	Biological process	-
ABCD1	215	ATP-binding cassette, sub-family D (ALD), member 1	protein binding	Molecular function	10551832
SOX12	6666	SRY (sex determining region Y)-box 12	cellular_component	Cellular component	-
SREBF1	6720	sterol regulatory element binding transcription factor 1	regulation of protein stability	Biological process	24912190
CREM	1390	cAMP responsive element modulator	signal transduction	Biological process	7916662
AKR1C2	1646	aldo-keto reductase family 1, member C2	positive regulation of cell proliferation	Biological process	18508192
POU3F1	5453	POU class 3 homeobox 1	RNA polymerase II transcription coactivator activity	Molecular function	-
ATG4C	84938	autophagy related 4C, cysteine peptidase	cytoplasm	Cellular component	12446702
PRDM8	56978	PR domain containing 8	histone H3-K9 methylation	Biological process	-
PLCH1	23007	phospholipase C, eta 1	inositol phosphate metabolic process	Biological process	-
RFPL4A	342931	ret finger protein-like 4A	zinc ion binding	Molecular function	-
GATA3	2625	GATA binding protein 3	cellular response to BMP stimulus	Biological process	-
KRT17	3872	keratin 17, type I	intermediate filament	Cellular component	-
HAL	3034	histidine ammonia-lyase	histidine catabolic process to glutamate and formate	Biological process	-
DENND4B	9909	DENN/MADD domain containing 4B	Golgi apparatus	Cellular component	-
CLTC	1213	clathrin, heavy chain (Hc)	protein complex	Cellular component	21266579
CALR	811	calreticulin	positive regulation of cell proliferation	Biological process	14726956
TRIB2	28951	tribbles pseudokinase 2	ubiquitin protein ligase binding	Molecular function	20410507
PRDX5	25824	peroxiredoxin 5	response to oxidative stress	Biological process	10514471
NOTCH1	4851	notch 1	axonogenesis	Biological process	-
ALKBH4	54784	alkB, alkylation repair homolog 4 (E. coli)	metal ion binding	Molecular function	-
MC3R	4159	melanocortin 3 receptor	melanocortin receptor activity	Molecular function	8175743
MELK	9833	maternal embryonic leucine zipper kinase	protein autophosphorylation	Biological process	16216881
GLB1L2	89944	galactosidase, beta 1-like 2	beta-galactosidase activity	Molecular function	-
AICDA	57379	activation-induced cytidine deaminase	protein binding	Molecular function	18722174
MPP1	4354	membrane protein, palmitoylated 1, 55kDa	protein binding	Molecular function	17584769
CLDN23	137075	claudin 23	identical protein binding	Molecular function	-
ETV2	2116	ets variant 2	cell differentiation	Biological process	-
ZNF211	10520	zinc finger protein 211	regulation of transcription, DNA-templated	Biological process	-
MMP2	4313	matrix metallopeptidase 2	zinc ion binding	Molecular function	-
TK2	7084	thymidine kinase 2, mitochondrial	nucleobase-containing compound metabolic process	Biological process	9079672
MFSD8	256471	major facilitator superfamily domain containing 8	integral component of membrane	Cellular component	-
SMAD4	4089	SMAD family member 4	intracellular signal transduction	Biological process	22316667
ZFP82	284406	ZFP82 zinc finger protein	sequence-specific DNA binding transcription factor activity	Molecular function	-
FKBP1B	2281	FK506 binding protein 1B, 12.6 kDa	cytoplasm	Cellular component	12443530
DGKZ	8525	diacylglycerol kinase, zeta	mitotic G1 DNA damage checkpoint	Biological process	16286473
GNB2L1	10399	guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1	cytosol	Cellular component	19767770
CUL3	8452	cullin 3	protein monoubiquitination	Biological process	22358839
PHF1	5252	PHD finger protein 1	sequence-specific DNA binding transcription factor activity	Molecular function	9545646
ADAM7	8756	ADAM metallopeptidase domain 7	zinc ion binding	Molecular function	-
STIL	6491	SCL/TAL1 interrupting locus	in utero embryonic development	Biological process	-
TCF3	6929	transcription factor 3	histone H3 acetylation	Biological process	-
UBL4A	8266	ubiquitin-like 4A	tail-anchored membrane protein insertion into ER membrane	Biological process	20676083
SRP14	6727	signal recognition particle 14kDa (homologous Alu RNA binding protein)	SRP-dependent cotranslational protein targeting to membrane	Biological process	-
TTPA	7274	tocopherol (alpha) transfer protein	embryonic placenta development	Biological process	-
NKX2-3	159296	NK2 homeobox 3	molecular_function	Molecular function	-
DMC1	11144	DNA meiotic recombinase 1	chromosome	Cellular component	-
RRM2B	50484	ribonucleotide reductase M2 B (TP53 inducible)	extracellular exosome	Cellular component	23376485
OR6Y1	391112	olfactory receptor, family 6, subfamily Y, member 1	sensory perception of smell	Biological process	-
CYTH2	9266	cytohesin 2	positive regulation of GTPase activity	Biological process	9417041
KIFC1	3833	kinesin family member C1	ATP binding	Molecular function	8276466
CREB5	9586	cAMP responsive element binding protein 5	sequence-specific DNA binding transcription factor activity	Molecular function	8378084
NHLH2	4808	nescient helix loop helix 2	sequence-specific DNA binding RNA polymerase II transcription factor activity	Molecular function	-
SCUBE2	57758	signal peptide, CUB domain, EGF-like 2	calcium ion binding	Molecular function	-
TGM1	7051	transglutaminase 1	protein-glutamine gamma-glutamyltransferase activity	Molecular function	21282207
WNT9B	7484	wingless-type MMTV integration site family, member 9B	Wnt signaling pathway	Biological process	-
NSF	4905	N-ethylmaleimide-sensitive factor	protein complex binding	Molecular function	15613468
OR7E24	26648	olfactory receptor, family 7, subfamily E, member 24	G-protein coupled receptor activity	Molecular function	-
SYP	6855	synaptophysin	protein complex binding	Molecular function	-
ATG4D	84971	autophagy related 4D, cysteine peptidase	cellular response to nitrogen starvation	Biological process	-
CDKN2A	1029	cyclin-dependent kinase inhibitor 2A	negative regulation of NF-kappaB transcription factor activity	Biological process	10353611
CLCN4	1183	chloride channel, voltage-sensitive 4	ion transmembrane transport	Biological process	-
DMAP1	55929	DNA methyltransferase 1 associated protein 1	negative regulation of transcription, DNA-templated	Biological process	10888872
PRMT1	3276	protein arginine methyltransferase 1	identical protein binding	Molecular function	16169070
LTBR	4055	lymphotoxin beta receptor (TNFR superfamily, member 3)	identical protein binding	Molecular function	20732415
PROM2	150696	prominin 2	cell projection	Cellular component	23583380
MAP3K5	4217	mitogen-activated protein kinase kinase kinase 5	protein binding	Molecular function	11003656
SLU7	10569	SLU7 splicing factor homolog (S. cerevisiae)	small nuclear ribonucleoprotein complex	Cellular component	15181151
PPT1	5538	palmitoyl-protein thioesterase 1	nucleus	Cellular component	10992246
GPCPD1	56261	glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)	skeletal muscle tissue development	Biological process	-
TMEM173	340061	transmembrane protein 173	positive regulation of protein binding	Biological process	18818105
SCN5A	6331	sodium channel, voltage gated, type V alpha subunit	regulation of atrial cardiac muscle cell membrane repolarization	Biological process	19167345
HIST1H2AK	8330	histone cluster 1, H2ak	biological_process	Biological process	-
UBE2W	55284	ubiquitin-conjugating enzyme E2W (putative)	misfolded or incompletely synthesized protein catabolic process	Biological process	-
NCOA4	8031	nuclear receptor coactivator 4	transcription, DNA-templated	Biological process	-
PRDM16	63976	PR domain containing 16	palate development	Biological process	-
GLI3	2737	GLI family zinc finger 3	lung development	Biological process	-
CHMP7	91782	charged multivesicular body protein 7	endosomal transport	Biological process	-
VPS45	11311	vacuolar protein sorting 45 homolog (S. cerevisiae)	endosome membrane	Cellular component	-
PIK3R1	5295	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	nucleus	Cellular component	-
CHRNA3	1136	cholinergic receptor, nicotinic, alpha 3 (neuronal)	integral component of membrane	Cellular component	8906617
GNAS	2778	GNAS complex locus	mu-type opioid receptor binding	Molecular function	-
OTC	5009	ornithine carbamoyltransferase	mitochondrion	Cellular component	-
OTUD7B	56957	OTU deubiquitinase 7B	DNA binding	Molecular function	-
RPL32	6161	ribosomal protein L32	translation	Biological process	-
ZZEF1	23140	zinc finger, ZZ-type with EF-hand domain 1	zinc ion binding	Molecular function	-
GDPD5	81544	glycerophosphodiester phosphodiesterase domain containing 5	spinal cord motor neuron differentiation	Biological process	-
BBS9	27241	Bardet-Biedl syndrome 9	cilium	Cellular component	22139371
VGF	7425	VGF nerve growth factor inducible	molecular_function	Molecular function	-
MAPK8IP2	23542	mitogen-activated protein kinase 8 interacting protein 2	regulation of receptor activity	Biological process	-
MAGI3	260425	membrane associated guanylate kinase, WW and PDZ domain containing 3	nucleotide phosphorylation	Biological process	10748157
PRRG2	5639	proline rich Gla (G-carboxyglutamic acid) 2	calcium ion binding	Molecular function	-
HLA-DOB	3112	major histocompatibility complex, class II, DO beta	signal transduction	Biological process	2998758
F2RL1	2150	coagulation factor II (thrombin) receptor-like 1	positive regulation of superoxide anion generation	Biological process	11714832
SNF8	11267	SNF8, ESCRT-II complex subunit	positive regulation of protein catabolic process	Biological process	17959629
SKA1	220134	spindle and kinetochore associated complex subunit 1	microtubule binding	Molecular function	19289083
IGHA1	3493	immunoglobulin heavy constant alpha 1	protein-chromophore linkage	Biological process	-
KRT73	319101	keratin 73, type II	structural molecule activity	Molecular function	-
HES7	84667	hes family bHLH transcription factor 7	Notch signaling pathway	Biological process	-
DYNC1I1	1780	dynein, cytoplasmic 1, intermediate chain 1	spectrin binding	Molecular function	23704327
ANKRD11	29123	ankyrin repeat domain 11	multicellular organism growth	Biological process	-
UCHL1	7345	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)	cytoplasm	Cellular component	16130169
HEY2	23493	hes-related family bHLH transcription factor with YRPW motif 2	labyrinthine layer blood vessel development	Biological process	-
GNL2	29889	guanine nucleotide binding protein-like 2 (nucleolar)	nucleolus	Cellular component	-
GK	2710	glycerol kinase	glycerol kinase activity	Molecular function	8401584
SNRNP40	9410	small nuclear ribonucleoprotein 40kDa (U5)	protein binding	Molecular function	9774689
JAK2	3717	Janus kinase 2	regulation of apoptotic process	Biological process	-
PTH1R	5745	parathyroid hormone 1 receptor	plasma membrane	Cellular component	-
RAG1	5896	recombination activating gene 1	V(D)J recombination	Biological process	-
SVIL	6840	supervillin	plasma membrane	Cellular component	-
PTGIR	5739	prostaglandin I2 (prostacyclin) receptor (IP)	integral component of plasma membrane	Cellular component	7512962
USP3	9960	ubiquitin specific peptidase 3	DNA repair	Biological process	17980597
ACOXL	55289	acyl-CoA oxidase-like	acyl-CoA oxidase activity	Molecular function	-
E4F1	1877	E4F transcription factor 1	transcription coactivator activity	Molecular function	9121437
ITPR3	3710	inositol 1,4,5-trisphosphate receptor, type 3	nucleoplasm	Cellular component	-
PFKM	5213	phosphofructokinase, muscle	small molecule metabolic process	Biological process	-
GAL3ST3	89792	galactose-3-O-sulfotransferase 3	proteoglycan sulfotransferase activity	Molecular function	11323440
LMLN	89782	leishmanolysin-like (metallopeptidase M8 family)	cell division	Biological process	-
NCF2	4688	neutrophil cytosolic factor 2	cytoplasm	Cellular component	-
ZSCAN4	201516	zinc finger and SCAN domain containing 4	transcription, DNA-templated	Biological process	-
TMEM126B	55863	transmembrane protein 126B	integral component of membrane	Cellular component	-
PEX2	5828	peroxisomal biogenesis factor 2	zinc ion binding	Molecular function	-
PLCG2	5336	phospholipase C, gamma 2 (phosphatidylinositol-specific)	protein binding	Molecular function	15644415
FGD2	221472	FYVE, RhoGEF and PH domain containing 2	neurotrophin TRK receptor signaling pathway	Biological process	-
FOXE1	2304	forkhead box E1	sequence-specific DNA binding	Molecular function	-
MRPS24	64951	mitochondrial ribosomal protein S24	mitochondrial small ribosomal subunit	Cellular component	10938081
PRLR	5618	prolactin receptor	regulation of cell adhesion	Biological process	-
AGR3	155465	anterior gradient 3	biological_process	Biological process	-
CAPN2	824	calpain 2, (m/II) large subunit	protein binding	Molecular function	10639123
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	neural plate development	Biological process	-
AKAP9	10142	A kinase (PRKA) anchor protein 9	intracellular membrane-bounded organelle	Cellular component	-
ELF2	1998	E74-like factor 2 (ets domain transcription factor)	negative regulation of transcription, DNA-templated	Biological process	14970218
STX1A	6804	syntaxin 1A (brain)	plasma membrane	Cellular component	10099709
RDH10	157506	retinol dehydrogenase 10 (all-trans)	retinoic acid biosynthetic process	Biological process	-
SMC1A	8243	structural maintenance of chromosomes 1A	chromosome	Cellular component	-
PCSK4	54760	proprotein convertase subtilisin/kexin type 4	acrosome reaction	Biological process	-
VIL1	7429	villin 1	cytoplasm	Cellular component	-
TC2N	123036	tandem C2 domains, nuclear	plasma membrane	Cellular component	-
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	cell fate specification	Biological process	-
RPL39	6170	ribosomal protein L39	structural constituent of ribosome	Molecular function	8764829
SPATA7	55812	spermatogenesis associated 7	protein binding	Molecular function	25398945
DHX36	170506	DEAH (Asp-Glu-Ala-His) box polypeptide 36	core promoter binding	Molecular function	21586581
HYAL2	8692	hyaluronoglucosaminidase 2	receptor signaling protein tyrosine kinase inhibitor activity	Molecular function	12676986
MAN1A2	10905	mannosidase, alpha, class 1A, member 2	extracellular exosome	Cellular component	19199708
USP1	7398	ubiquitin specific peptidase 1	ubiquitin-specific protease activity	Molecular function	20129063
PLCB1	23236	phospholipase C, beta 1 (phosphoinositide-specific)	positive regulation of CD24 biosynthetic process	Biological process	-
PSMD10	5716	proteasome (prosome, macropain) 26S subunit, non-ATPase, 10	proteasome complex	Cellular component	17323924
CSNK2B	1460	casein kinase 2, beta polypeptide	axon guidance	Biological process	-
CLP1	10978	cleavage and polyadenylation factor I subunit 1	polydeoxyribonucleotide kinase activity	Molecular function	17495927
GEMIN4	50628	gem (nuclear organelle) associated protein 4	protein binding	Molecular function	11714716
KRT82	3888	keratin 82, type II	keratin filament	Cellular component	10692104
POLR3GL	84265	polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like	termination of RNA polymerase III transcription	Biological process	-
FMNL2	114793	formin-like 2	cytoskeleton organization	Biological process	21834987
GRB2	2885	growth factor receptor-bound protein 2	small GTPase mediated signal transduction	Biological process	-
SLC26A9	115019	solute carrier family 26 (anion exchanger), member 9	integral component of membrane	Cellular component	-
SMARCE1	6605	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	nBAF complex	Cellular component	-
IFT57	55081	intraflagellar transport 57	apoptotic process	Biological process	11788820
MARCKS	4082	myristoylated alanine-rich protein kinase C substrate	energy reserve metabolic process	Biological process	-
MUC17	140453	mucin 17, cell surface associated	Golgi lumen	Cellular component	-
PSMB5	5693	proteasome (prosome, macropain) subunit, beta type, 5	programmed cell death	Biological process	-
STK4	6789	serine/threonine kinase 4	nucleus	Cellular component	-
CCL8	6355	chemokine (C-C motif) ligand 8	protein kinase activity	Molecular function	10734056
CDH2	1000	cadherin 2, type 1, N-cadherin (neuronal)	cell-cell adhesion mediated by cadherin	Biological process	-
TH	7054	tyrosine hydroxylase	terminal bouton	Cellular component	-
RP2	6102	retinitis pigmentosa 2 (X-linked recessive)	cell morphogenesis	Biological process	-
PPP1CB	5500	protein phosphatase 1, catalytic subunit, beta isozyme	glycogen metabolic process	Biological process	-
CXCL9	4283	chemokine (C-X-C motif) ligand 9	inflammatory response	Biological process	-
HPGDS	27306	hematopoietic prostaglandin D synthase	glutathione derivative biosynthetic process	Biological process	-
NTAN1	123803	N-terminal asparagine amidase	metabolic process	Biological process	-
TCN2	6948	transcobalamin II	small molecule metabolic process	Biological process	-
TRAF3IP2	10758	TRAF3 interacting protein 2	B cell apoptotic process	Biological process	-
LTBP4	8425	latent transforming growth factor beta binding protein 4	calcium ion binding	Molecular function	9660815
ACAN	176	aggrecan	extracellular matrix structural constituent	Molecular function	1569188
RAD51	5888	RAD51 recombinase	DNA unwinding involved in DNA replication	Biological process	7988572
LUC7L3	51747	LUC7-like 3 (S. cerevisiae)	RNA splicing	Biological process	10631324
TBX20	57057	T-box 20	RNA polymerase II activating transcription factor binding	Molecular function	-
SRR	63826	serine racemase	L-serine metabolic process	Biological process	11054547
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	mesenchymal to epithelial transition involved in metanephros morphogenesis	Biological process	-
AHCYL1	10768	adenosylhomocysteinase-like 1	apical plasma membrane	Cellular component	-
KANK1	23189	KN motif and ankyrin repeat domains 1	protein binding	Molecular function	16968744
RPS16	6217	ribosomal protein S16	translational elongation	Biological process	-
HTATIP2	10553	HIV-1 Tat interactive protein 2, 30kDa	cytoplasm	Cellular component	-
TOMM7	54543	translocase of outer mitochondrial membrane 7 homolog (yeast)	activation of mitophagy in response to mitochondrial depolarization	Biological process	24270810
PAPD7	11044	PAP associated domain containing 7	double-strand break repair	Biological process	10066793
RAB9B	51209	RAB9B, member RAS oncogene family	metabolic process	Biological process	-
DNAJC19	131118	DnaJ (Hsp40) homolog, subfamily C, member 19	protein complex	Cellular component	19564938
CNTN1	1272	contactin 1	plasma membrane	Cellular component	-
KLHL35	283212	kelch-like family member 35	protein binding	Molecular function	25416956
CLUH	23277	clustered mitochondria (cluA/CLU1) homolog	intracellular distribution of mitochondria	Biological process	25349259
GNG13	51764	guanine nucleotide binding protein (G protein), gamma 13	energy reserve metabolic process	Biological process	-
ADM	133	adrenomedullin	developmental growth	Biological process	-
NCOA5	57727	nuclear receptor coactivator 5	protein binding	Molecular function	11113208
TENM3	55714	teneurin transmembrane protein 3	self proteolysis	Biological process	-
EEF2	1938	eukaryotic translation elongation factor 2	translational elongation	Biological process	-
RARA	5914	retinoic acid receptor, alpha	face development	Biological process	-
CORO1B	57175	coronin, actin binding protein, 1B	cell migration	Biological process	16027158
SYT11	23208	synaptotagmin XI	cell junction	Cellular component	-
HIPK2	28996	homeodomain interacting protein kinase 2	positive regulation of cell proliferation	Biological process	-
NEURL1	9148	neuralized E3 ubiquitin protein ligase 1	plasma membrane	Cellular component	20847082
IFT57	55081	intraflagellar transport 57	ciliary tip	Cellular component	-
RPP25	54913	ribonuclease P/MRP 25kDa subunit	ribonuclease P activity	Molecular function	-
CCDC64	92558	coiled-coil domain containing 64	Golgi to secretory granule transport	Biological process	-
CHD6	84181	chromodomain helicase DNA binding protein 6	ATP binding	Molecular function	-
GATA6	2627	GATA binding protein 6	type B pancreatic cell differentiation	Biological process	-
STRADB	55437	STE20-related kinase adaptor beta	protein binding	Molecular function	14676191
MAPRE2	10982	microtubule-associated protein, RP/EB family, member 2	cytoplasm	Cellular component	16791210
DNAJB2	3300	DnaJ (Hsp40) homolog, subfamily B, member 2	unfolded protein binding	Molecular function	21231916
RBM22	55696	RNA binding motif protein 22	snRNA binding	Molecular function	22246180
UBE4A	9354	ubiquitination factor E4A	ubiquitin-dependent protein catabolic process	Biological process	-
ECE1	1889	endothelin converting enzyme 1	positive regulation of receptor recycling	Biological process	18039931
MEN1	4221	multiple endocrine neoplasia I	cytoplasm	Cellular component	-
LAT2	7462	linker for activation of T cells family, member 2	mast cell degranulation	Biological process	-
SRF	6722	serum response factor (c-fos serum response element-binding transcription factor)	cell-matrix adhesion	Biological process	-
DLG3	1741	discs, large homolog 3 (Drosophila)	basolateral plasma membrane	Cellular component	-
DHX15	1665	DEAH (Asp-Glu-Ala-His) box helicase 15	mRNA processing	Biological process	-
EGLN1	54583	egl-9 family hypoxia-inducible factor 1	oxygen homeostasis	Biological process	16956324
KCNH2	3757	potassium channel, voltage gated eag related subfamily H, member 2	potassium ion export across plasma membrane	Biological process	25281747
TALDO1	6888	transaldolase 1	small molecule metabolic process	Biological process	-
CHRM3	1131	cholinergic receptor, muscarinic 3	basolateral plasma membrane	Cellular component	-
GNE	10020	glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase	UDP-N-acetylglucosamine metabolic process	Biological process	-
SRP68	6730	signal recognition particle 68kDa	ribosome	Cellular component	10618370
AGO1	26523	argonaute RISC catalytic component 1	Fc-epsilon receptor signaling pathway	Biological process	-
OMA1	115209	OMA1 zinc metallopeptidase	cristae formation	Biological process	-
ARG1	383	arginase 1	neuronal cell body	Cellular component	-
MST1	4485	macrophage stimulating 1	extracellular exosome	Cellular component	23376485
TNFRSF21	27242	tumor necrosis factor receptor superfamily, member 21	cellular response to tumor necrosis factor	Biological process	19654028
ALDH3A2	224	aldehyde dehydrogenase 3 family, member A2	sesquiterpenoid metabolic process	Biological process	18035827
HERC5	51191	HECT and RLD domain containing E3 ubiquitin protein ligase 5	perinuclear region of cytoplasm	Cellular component	-
CCNA2	890	cyclin A2	protein kinase binding	Molecular function	-
GMPPB	29925	GDP-mannose pyrophosphorylase B	mannose-1-phosphate guanylyltransferase activity	Molecular function	-
CDH3	1001	cadherin 3, type 1, P-cadherin (placental)	hair cycle process	Biological process	23143461
OR5B17	219965	olfactory receptor, family 5, subfamily B, member 17	odorant binding	Molecular function	-
FLOT1	10211	flotillin 1	microtubule organizing center	Cellular component	18000879
MRPL48	51642	mitochondrial ribosomal protein L48	mitochondrial translational termination	Biological process	-
TACSTD2	4070	tumor-associated calcium signal transducer 2	negative regulation of epithelial cell migration	Biological process	-
SMAD9	4093	SMAD family member 9	transcription, DNA-templated	Biological process	-
PAM	5066	peptidylglycine alpha-amidating monooxygenase	peptidylglycine monooxygenase activity	Molecular function	12699694
PON1	5444	paraoxonase 1	response to external stimulus	Biological process	1657140
GNB3	2784	guanine nucleotide binding protein (G protein), beta polypeptide 3	G-protein coupled receptor signaling pathway	Biological process	2107550
SARM1	23098	sterile alpha and TIR motif containing 1	innate immune response	Biological process	-
MYF5	4617	myogenic factor 5	muscle cell fate commitment	Biological process	-
RNF10	9921	ring finger protein 10	protein autoubiquitination	Biological process	24105792
PTPN3	5774	protein tyrosine phosphatase, non-receptor type 3	sodium channel regulator activity	Molecular function	16930557
CDH16	1014	cadherin 16, KSP-cadherin	homophilic cell adhesion via plasma membrane adhesion molecules	Biological process	-
UGT2B15	7366	UDP glucuronosyltransferase 2 family, polypeptide B15	steroid metabolic process	Biological process	7835232
CD248	57124	CD248 molecule, endosialin	cytoplasm	Cellular component	-
TEFM	79736	transcription elongation factor, mitochondrial	mitochondrial DNA replication	Biological process	21278163
RLF	6018	rearranged L-myc fusion	DNA binding	Molecular function	8545128
KCNA5	3741	potassium channel, voltage gated shaker related subfamily A, member 5	caveola	Cellular component	17060380
ZNF786	136051	zinc finger protein 786	nucleus	Cellular component	-
BRD9	65980	bromodomain containing 9	biological_process	Biological process	-
OXNAD1	92106	oxidoreductase NAD-binding domain containing 1	oxidoreductase activity	Molecular function	-
MMP24	10893	matrix metallopeptidase 24 (membrane-inserted)	glial cell differentiation	Biological process	-
RRS1	23212	RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)	endoplasmic reticulum	Cellular component	-
XRCC5	7520	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	ATP-dependent DNA helicase activity	Molecular function	-
MSR1	4481	macrophage scavenger receptor 1	collagen trimer	Cellular component	-
SUMF2	25870	sulfatase modifying factor 2	cellular protein metabolic process	Biological process	-
ASIC3	9311	acid sensing (proton gated) ion channel 3	integral component of plasma membrane	Cellular component	-
SLC1A3	6507	solute carrier family 1 (glial high affinity glutamate transporter), member 3	membrane	Cellular component	7521911
STKLD1	169436	serine/threonine kinase-like domain containing 1	protein phosphorylation	Biological process	-
KCNE2	9992	potassium channel, voltage gated subfamily E regulatory beta subunit 2	potassium ion export	Biological process	10219239
GLIS2	84662	GLIS family zinc finger 2	nucleus	Cellular component	-
GPLD1	2822	glycosylphosphatidylinositol specific phospholipase D1	positive regulation of insulin secretion involved in cellular response to glucose stimulus	Biological process	-
WASL	8976	Wiskott-Aldrich syndrome-like	spindle localization	Biological process	-
HAAO	23498	3-hydroxyanthranilate 3,4-dioxygenase	'de novo' NAD biosynthetic process from tryptophan	Biological process	-
SEPHS2	22928	selenophosphate synthetase 2	selenide, water dikinase activity	Molecular function	8986768
SLC6A14	11254	solute carrier family 6 (amino acid transporter), member 14	plasma membrane	Cellular component	-
PICK1	9463	protein interacting with PRKCA 1	plasma membrane	Cellular component	-
RPL32	6161	ribosomal protein L32	cytosol	Cellular component	-
INS-IGF2	723961	INS-IGF2 readthrough	extracellular region	Cellular component	-
HAUS1	115106	HAUS augmin-like complex, subunit 1	protein binding	Molecular function	21516116
CPTP	80772	ceramide-1-phosphate transfer protein	phospholipid transporter activity	Molecular function	23863933
DTNA	1837	dystrobrevin, alpha	cytoplasm	Cellular component	-
BIRC2	329	baculoviral IAP repeat containing 2	membrane raft	Cellular component	-
TMEM237	65062	transmembrane protein 237	ciliary transition zone	Cellular component	22152675
IL1B	3553	interleukin 1, beta	cell-cell signaling	Biological process	2989698
ZNF646	9726	zinc finger protein 646	nucleus	Cellular component	-
PMCHL2	5370	pro-melanin-concentrating hormone-like 2, pseudogene	molecular_function	Molecular function	-
CD8A	925	CD8a molecule	plasma membrane	Cellular component	-
NKAIN3	286183	Na+/K+ transporting ATPase interacting 3	integral component of membrane	Cellular component	-
DOCK7	85440	dedicator of cytokinesis 7	guanyl-nucleotide exchange factor activity	Molecular function	-
CSNK1G3	1456	casein kinase 1, gamma 3	Wnt signaling pathway	Biological process	-
WDPCP	51057	WD repeat containing planar cell polarity effector	digestive system development	Biological process	-
CCDC8	83987	coiled-coil domain containing 8	regulation of mitotic nuclear division	Biological process	24793695
PIKFYVE	200576	phosphoinositide kinase, FYVE finger containing	receptor-mediated endocytosis	Biological process	14551253
CHMP2A	27243	charged multivesicular body protein 2A	positive regulation of viral release from host cell	Biological process	14505570
PLEK	5341	pleckstrin	actin cytoskeleton reorganization	Biological process	10497244
RGS1	5996	regulator of G-protein signaling 1	plasma membrane	Cellular component	10480894
SP100	6672	SP100 nuclear antigen	response to cytokine	Biological process	11313457
SORD	6652	sorbitol dehydrogenase	carbohydrate binding	Molecular function	12962626
ATP6V1D	51382	ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D	centrosome	Cellular component	21844891
DCTN4	51164	dynactin 4 (p62)	centrosome	Cellular component	21399614
FBXW11	23291	F-box and WD repeat domain containing 11	nucleus	Cellular component	-
SLC26A8	116369	solute carrier family 26 (anion exchanger), member 8	meiotic cell cycle	Biological process	-
ESPL1	9700	extra spindle pole bodies homolog 1 (S. cerevisiae)	positive regulation of mitotic metaphase/anaphase transition	Biological process	12672959
MAZ	4150	MYC-associated zinc finger protein (purine-binding transcription factor)	protein binding	Molecular function	11527412
RCC2	55920	regulator of chromosome condensation 2	positive regulation of attachment of spindle microtubules to kinetochore	Biological process	12919680
UQCRC2	7385	ubiquinol-cytochrome c reductase core protein II	extracellular exosome	Cellular component	23376485
SLC6A6	6533	solute carrier family 6 (neurotransmitter transporter), member 6	transmembrane transport	Biological process	-
TFCP2L1	29842	transcription factor CP2-like 1	female pregnancy	Biological process	10644752
FGFR2	2263	fibroblast growth factor receptor 2	pyramidal neuron development	Biological process	-
NRG1	3084	neuregulin 1	locomotory behavior	Biological process	-
STX16	8675	syntaxin 16	intracellular membrane-bounded organelle	Cellular component	-
PPP1R26	9858	protein phosphatase 1, regulatory subunit 26	nucleoplasm	Cellular component	-
PMS2	5395	PMS2 postmeiotic segregation increased 2 (S. cerevisiae)	endonuclease activity	Molecular function	-
CCDC51	79714	coiled-coil domain containing 51	mitochondrion	Cellular component	-
ARFGEF2	10564	ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)	protein transport	Biological process	-
MPZL2	10205	myelin protein zero-like 2	protein binding	Molecular function	21982860
SGCA	6442	sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)	protein binding	Molecular function	21516116
OLFM1	10439	olfactomedin 1	atrioventricular valve formation	Biological process	-
ARF4	378	ADP-ribosylation factor 4	protein binding	Molecular function	17956946
PRIM2	5558	primase, DNA, polypeptide 2 (58kDa)	metal ion binding	Molecular function	-
RAC1	5879	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	thioesterase binding	Molecular function	12612085
WNT2B	7482	wingless-type MMTV integration site family, member 2B	hematopoietic stem cell proliferation	Biological process	9787155
C1QTNF6	114904	C1q and tumor necrosis factor related protein 6	protein binding	Molecular function	25416956
CYP2A7	1549	cytochrome P450, family 2, subfamily A, polypeptide 7	oxidation-reduction process	Biological process	-
NFE2	4778	nuclear factor, erythroid 2	regulation of transcription from RNA polymerase II promoter	Biological process	-
JAK2	3717	Janus kinase 2	positive regulation of inflammatory response	Biological process	-
RGPD2	729857	RANBP2-like and GRIP domain containing 2	intracellular	Cellular component	-
METTL23	124512	methyltransferase like 23	methyltransferase activity	Molecular function	-
SCAP	22937	SREBF chaperone	response to insulin	Biological process	-
SHC1	6464	SHC (Src homology 2 domain containing) transforming protein 1	insulin receptor signaling pathway	Biological process	-
HCK	3055	HCK proto-oncogene, Src family tyrosine kinase	actin filament	Cellular component	15998323
LONP1	9361	lon peptidase 1, mitochondrial	protein binding	Molecular function	14739292
CDK1	983	cyclin-dependent kinase 1	response to activity	Biological process	-
MAFA	389692	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A	response to glucose	Biological process	12368292
ETS1	2113	v-ets avian erythroblastosis virus E26 oncogene homolog 1	female pregnancy	Biological process	-
CBX7	23492	chromobox homolog 7	protein binding	Molecular function	10369680
TAF4B	6875	TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa	gene expression	Biological process	-
ACTB	60	actin, beta	protein kinase binding	Molecular function	-
WNT7B	7477	wingless-type MMTV integration site family, member 7B	establishment or maintenance of polarity of embryonic epithelium	Biological process	-
TRIP11	9321	thyroid hormone receptor interactor 11	ventricular septum development	Biological process	-
PROS1	5627	protein S (alpha)	leukocyte migration	Biological process	-
NAGA	4668	N-acetylgalactosaminidase, alpha-	glycoside catabolic process	Biological process	-
E2F2	1870	E2F transcription factor 2	protein binding	Molecular function	16360038
VCAN	1462	versican	dermatan sulfate biosynthetic process	Biological process	-
EHMT2	10919	euchromatic histone-lysine N-methyltransferase 2	histone methylation	Biological process	22387026
CDK6	1021	cyclin-dependent kinase 6	cell cycle arrest	Biological process	16294322
PAPOLA	10914	poly(A) polymerase alpha	nucleus	Cellular component	8302877
FOXF1	2294	forkhead box F1	epithelial cell differentiation involved in mammary gland alveolus development	Biological process	-
HADH	3033	hydroxyacyl-CoA dehydrogenase	3-hydroxyacyl-CoA dehydrogenase activity	Molecular function	-
STX7	8417	syntaxin 7	organelle assembly	Biological process	21438968
BTRC	8945	beta-transducin repeat containing E3 ubiquitin protein ligase	G2/M transition of mitotic cell cycle	Biological process	-
HEY2	23493	hes-related family bHLH transcription factor with YRPW motif 2	muscular septum morphogenesis	Biological process	-
ADGRF5	221395	adhesion G protein-coupled receptor F5	cell surface	Cellular component	23684610
IGKV3-20	28912	immunoglobulin kappa variable 3-20	receptor-mediated endocytosis	Biological process	-
ECE1	1889	endothelin converting enzyme 1	perinuclear region of cytoplasm	Cellular component	9710124
MTCH1	23787	mitochondrial carrier 1	intracellular	Cellular component	10551805
ITGAL	3683	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	leukocyte cell-cell adhesion	Biological process	2477710
IL4	3565	interleukin 4	dendritic cell differentiation	Biological process	21149635
RAN	5901	RAN, member RAS oncogene family	ribosomal large subunit export from nucleus	Biological process	12773398
LRRC15	131578	leucine rich repeat containing 15	receptor-mediated virion attachment to host cell	Biological process	18385238
POLR2F	5435	polymerase (RNA) II (DNA directed) polypeptide F	somatic stem cell maintenance	Biological process	-
DYM	54808	dymeclin	Golgi apparatus	Cellular component	-
NDC1	55706	NDC1 transmembrane nucleoporin	nuclear pore complex assembly	Biological process	16600873
ZDHHC7	55625	zinc finger, DHHC-type containing 7	nucleus	Cellular component	-
SLC9A1	6548	solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1	calcium-dependent protein binding	Molecular function	15035633
LMOD2	442721	leiomodin 2 (cardiac)	muscle contraction	Biological process	-
CLTCL1	8218	clathrin, heavy chain-like 1	membrane	Cellular component	19946888
ZNF385A	25946	zinc finger protein 385A	poly(A) RNA binding	Molecular function	22681889
COL10A1	1300	collagen, type X, alpha 1	protein binding	Molecular function	25416956
CCNL2	81669	cyclin L2	nuclear speck	Cellular component	-
NUSAP1	51203	nucleolar and spindle associated protein 1	cytoplasm	Cellular component	-
CD209	30835	CD209 molecule	metal ion binding	Molecular function	-
GART	2618	phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase	purine ribonucleoside monophosphate biosynthetic process	Biological process	-
ZDHHC1	29800	zinc finger, DHHC-type containing 1	integral component of membrane	Cellular component	-
MPZ	4359	myelin protein zero	synaptic transmission	Biological process	7693129
FSCN1	6624	fascin actin-bundling protein 1	protein binding, bridging	Molecular function	-
AK7	122481	adenylate kinase 7	cytoplasm	Cellular component	-
C11orf63	79864	chromosome 11 open reading frame 63	axoneme assembly	Biological process	-
TTR	7276	transthyretin	hormone activity	Molecular function	-
SPEM1	374768	spermatid maturation 1	cytoplasm	Cellular component	-
NUP160	23279	nucleoporin 160kDa	regulation of cellular response to heat	Biological process	-
PLP2	5355	proteolipid protein 2 (colonic epithelium-enriched)	ion transmembrane transport	Biological process	9124532
SLC38A5	92745	solute carrier family 38, member 5	glycine transmembrane transporter activity	Molecular function	-
GNB5	10681	guanine nucleotide binding protein (G protein), beta 5	rhodopsin mediated signaling pathway	Biological process	-
MCM10	55388	minichromosome maintenance complex component 10	mitotic cell cycle	Biological process	-
CASP3	836	caspase 3, apoptosis-related cysteine peptidase	protein binding	Molecular function	11257232
ZNF248	57209	zinc finger protein 248	metal ion binding	Molecular function	-
SERPINA3	12	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3	DNA binding	Molecular function	14668352
PDE6D	5147	phosphodiesterase 6D, cGMP-specific, rod, delta	negative regulation of GTPase activity	Biological process	-
CAPN2	824	calpain 2, (m/II) large subunit	dendrite	Cellular component	-
BIRC5	332	baculoviral IAP repeat containing 5	protein complex localization	Biological process	16239925
DCK	1633	deoxycytidine kinase	nucleoside kinase activity	Molecular function	-
TRIB1	10221	tribbles pseudokinase 1	mitogen-activated protein kinase kinase binding	Molecular function	15299019
RARA	5914	retinoic acid receptor, alpha	positive regulation of cell proliferation	Biological process	20080953
CYP17A1	1586	cytochrome P450, family 17, subfamily A, polypeptide 1	response to steroid hormone	Biological process	-
CEP350	9857	centrosomal protein 350kDa	microtubule binding	Molecular function	-
CHMP4C	92421	charged multivesicular body protein 4C	negative regulation of cytokinesis	Biological process	22422861
SLC27A2	11001	solute carrier family 27 (fatty acid transporter), member 2	very long-chain fatty acid catabolic process	Biological process	-
MSH6	2956	mutS homolog 6	response to UV	Biological process	-
NPM2	10361	nucleophosmin/nucleoplasmin 2	regulation of exit from mitosis	Biological process	12714744
CAMK2B	816	calcium/calmodulin-dependent protein kinase II beta	protein autophosphorylation	Biological process	18817731
OR10J5	127385	olfactory receptor, family 10, subfamily J, member 5	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
PTEN	5728	phosphatase and tensin homolog	phosphatidylinositol-mediated signaling	Biological process	-
HSP90B2P	7190	heat shock protein 90kDa beta (Grp94), member 2, pseudogene	unfolded protein binding	Molecular function	-
ATP5D	513	ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit	mitochondrial proton-transporting ATP synthase complex	Cellular component	1531933
GATA6	2627	GATA binding protein 6	cardiac vascular smooth muscle cell differentiation	Biological process	11889139
CC2D1A	54862	coiled-coil and C2 domain containing 1A	nucleus	Cellular component	-
SLC25A45	283130	solute carrier family 25, member 45	integral component of membrane	Cellular component	-
ELAVL1	1994	ELAV like RNA binding protein 1	AU-rich element binding	Molecular function	14517288
RRP9	9136	ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)	box C/D snoRNP complex	Cellular component	9418896
OSR1	130497	odd-skipped related transciption factor 1	embryonic skeletal joint morphogenesis	Biological process	-
NUDT16	131870	nudix (nucleoside diphosphate linked moiety X)-type motif 16	GTP binding	Molecular function	20385596
CFI	3426	complement factor I	receptor-mediated endocytosis	Biological process	-
CTNS	1497	cystinosin, lysosomal cystine transporter	extracellular exosome	Cellular component	19056867
TFAP2A	7020	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	oculomotor nerve formation	Biological process	-
FGFR2	2263	fibroblast growth factor receptor 2	lacrimal gland development	Biological process	-
KNDC1	85442	kinase non-catalytic C-lobe domain (KIND) containing 1	cerebellar granule cell differentiation	Biological process	-
CNNM3	26505	cyclin and CBS domain divalent metal cation transport mediator 3	plasma membrane	Cellular component	-
CDC42SE2	56990	CDC42 small effector 2	cytoskeleton	Cellular component	-
LIMA1	51474	LIM domain and actin binding 1	actin monomer binding	Molecular function	12566430
SP100	6672	SP100 nuclear antigen	cellular protein metabolic process	Biological process	-
PRSS47	138652	protease, serine, 47	serine-type endopeptidase activity	Molecular function	-
CACNG2	10369	calcium channel, voltage-dependent, gamma subunit 2	calcium ion transmembrane transport	Biological process	-
PLAUR	5329	plasminogen activator, urokinase receptor	receptor binding	Molecular function	12665524
WWTR1	25937	WW domain containing transcription regulator 1	cilium morphogenesis	Biological process	-
CSK	1445	c-src tyrosine kinase	protein C-terminus binding	Molecular function	8890164
VPS11	55823	vacuolar protein sorting 11 homolog (S. cerevisiae)	protein binding	Molecular function	21148287
S100A7	6278	S100 calcium binding protein A7	endoplasmic reticulum	Cellular component	12839573
ACE	1636	angiotensin I converting enzyme	regulation of renal output by angiotensin	Biological process	1668266
CCL5	6352	chemokine (C-C motif) ligand 5	positive regulation of cellular biosynthetic process	Biological process	18337562
TCF7	6932	transcription factor 7 (T-cell specific, HMG-box)	canonical Wnt signaling pathway involved in negative regulation of apoptotic process	Biological process	-
SAMM50	25813	SAMM50 sorting and assembly machinery component	mitochondrial inner membrane	Cellular component	-
HIST1H4F	8361	histone cluster 1, H4f	mitotic cell cycle	Biological process	-
SPTAN1	6709	spectrin, alpha, non-erythrocytic 1	spectrin binding	Molecular function	-
CDC5L	988	cell division cycle 5-like	regulation of transcription, DNA-templated	Biological process	-
RASSF1	11186	Ras association (RalGDS/AF-6) domain family member 1	microtubule organizing center	Cellular component	-
ZNF687	57592	zinc finger protein 687	metal ion binding	Molecular function	-
TREM2	54209	triggering receptor expressed on myeloid cells 2	positive regulation of CD40 signaling pathway	Biological process	11602640
SSC4D	136853	scavenger receptor cysteine rich family, 4 domains	extracellular exosome	Cellular component	23376485
MRPS31	10240	mitochondrial ribosomal protein S31	protein binding	Molecular function	21988832
TSPY2	64591	testis specific protein, Y-linked 2	nucleus	Cellular component	-
IPO5	3843	importin 5	nucleolus	Cellular component	-
PGLYRP4	57115	peptidoglycan recognition protein 4	extracellular region	Cellular component	-
CELF5	60680	CUGBP, Elav-like family member 5	cytoplasm	Cellular component	-
MEIS1	4211	Meis homeobox 1	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
UPF3A	65110	UPF3 regulator of nonsense transcripts homolog A (yeast)	positive regulation of translation	Biological process	16601204
COQ9	57017	coenzyme Q9	lipid binding	Molecular function	25339443
DHX9	1660	DEAH (Asp-Glu-Ala-His) box helicase 9	CRD-mediated mRNA stability complex	Cellular component	19029303
MAPK4	5596	mitogen-activated protein kinase 4	ATP binding	Molecular function	-
ITGA8	8516	integrin, alpha 8	plasma membrane	Cellular component	-
UBA52	7311	ubiquitin A-52 residue ribosomal protein fusion product 1	plasma membrane	Cellular component	-
SLC20A1	6574	solute carrier family 20 (phosphate transporter), member 1	plasma membrane	Cellular component	-
CNTNAP2	26047	contactin associated protein-like 2	integral component of membrane	Cellular component	11352571
ZNF514	84874	zinc finger protein 514	DNA binding	Molecular function	-
UGDH	7358	UDP-glucose 6-dehydrogenase	nucleoplasm	Cellular component	-
CDYL2	124359	chromodomain protein, Y-like 2	catalytic activity	Molecular function	-
DPRX	503834	divergent-paired related homeobox	transcription, DNA-templated	Biological process	-
SETD2	29072	SET domain containing 2	mesoderm morphogenesis	Biological process	-
CFAP58	159686	cilia and flagella associated protein 58	cilium	Cellular component	-
CREB3L1	90993	cAMP responsive element binding protein 3-like 1	sequence-specific DNA binding	Molecular function	-
KIR3DL1	3811	killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1	regulation of immune response	Biological process	-
UNK	85451	unkempt family zinc finger	poly(A) RNA binding	Molecular function	22658674
MYCN	4613	v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog	embryonic skeletal system morphogenesis	Biological process	-
ADCYAP1R1	117	adenylate cyclase activating polypeptide 1 (pituitary) receptor type I	rough endoplasmic reticulum	Cellular component	-
ZAP70	7535	zeta-chain (TCR) associated protein kinase 70kDa	positive thymic T cell selection	Biological process	7630421
DDIT3	1649	DNA-damage-inducible transcript 3	protein binding	Molecular function	15775988
TUBB6	84617	tubulin, beta 6 class V	cellular protein metabolic process	Biological process	-
SIRT1	23411	sirtuin 1	cellular response to DNA damage stimulus	Biological process	18203716
NOD2	64127	nucleotide-binding oligomerization domain containing 2	response to lipopolysaccharide	Biological process	-
APAF1	317	apoptotic peptidase activating factor 1	nucleotide binding	Molecular function	10383829
MYOD1	4654	myogenic differentiation 1	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	11076940
HIST2H2BE	8349	histone cluster 2, H2be	antibacterial humoral response	Biological process	12860195
ADGRE3	84658	adhesion G protein-coupled receptor E3	integral component of membrane	Cellular component	-
DEFB129	140881	defensin, beta 129	defense response to bacterium	Biological process	-
COL20A1	57642	collagen, type XX, alpha 1	extracellular matrix	Cellular component	22261194
RHAG	6005	Rh-associated glycoprotein	cellular ion homeostasis	Biological process	15856280
CALCA	796	calcitonin-related polypeptide alpha	positive regulation of interleukin-1 alpha production	Biological process	16904178
EIF2S1	1965	eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa	ribosome binding	Molecular function	17894550
RAB14	51552	RAB14, member RAS oncogene family	extracellular exosome	Cellular component	19056867
RPA1	6117	replication protein A1, 70kDa	DNA replication factor A complex	Cellular component	16135809
SCARF1	8578	scavenger receptor class F, member 1	transmembrane signaling receptor activity	Molecular function	9395444
EGFR	1956	epidermal growth factor receptor	diterpenoid metabolic process	Biological process	-
SNCA	6622	synuclein, alpha (non A4 component of amyloid precursor)	dynein binding	Molecular function	16176937
MTSS1	9788	metastasis suppressor 1	actin monomer binding	Molecular function	12570871
CALR	811	calreticulin	external side of plasma membrane	Cellular component	-
MNAT1	4331	MNAT CDK-activating kinase assembly factor 1	response to calcium ion	Biological process	-
PRH2	5555	proline-rich protein HaeIII subfamily 2	extracellular space	Cellular component	2993301
ISG20	3669	interferon stimulated exonuclease gene 20kDa	response to virus	Biological process	12594219
KIAA1324	57535	KIAA1324	late endosome membrane	Cellular component	-
POLD1	5424	polymerase (DNA directed), delta 1, catalytic subunit	small molecule metabolic process	Biological process	-
HOXB2	3212	homeobox B2	dorsal/ventral pattern formation	Biological process	-
OR2M2	391194	olfactory receptor, family 2, subfamily M, member 2	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
TRADD	8717	TNFRSF1A-associated via death domain	tumor necrosis factor-mediated signaling pathway	Biological process	8612133
MTUS1	57509	microtubule associated tumor suppressor 1	mitochondrion	Cellular component	-
ARPC2	10109	actin related protein 2/3 complex, subunit 2, 34kDa	cytoplasm	Cellular component	-
MAGEE1	57692	melanoma antigen family E1	nucleus	Cellular component	14623885
EFTUD1	79631	elongation factor Tu GTP binding domain containing 1	translational elongation	Biological process	-
CBS	875	cystathionine-beta-synthase	ubiquitin protein ligase binding	Molecular function	17087506
RPS6KB1	6198	ribosomal protein S6 kinase, 70kDa, polypeptide 1	protein kinase B signaling	Biological process	-
GFRA3	2676	GDNF family receptor alpha 3	sympathetic nervous system development	Biological process	-
ZNF639	51193	zinc finger protein 639	sequence-specific DNA binding transcription factor activity	Molecular function	16182284
ZHX2	22882	zinc fingers and homeoboxes 2	nucleus	Cellular component	12741956
CNTNAP4	85445	contactin associated protein-like 4	dendrite	Cellular component	-
FAM86C2P	645332	family with sequence similarity 86, member A pseudogene	methylation	Biological process	-
SIGLEC1	6614	sialic acid binding Ig-like lectin 1, sialoadhesin	plasma membrane	Cellular component	-
ESYT3	83850	extended synaptotagmin-like protein 3	endoplasmic reticulum	Cellular component	-
KRIT1	889	KRIT1, ankyrin repeat containing	cell redox homeostasis	Biological process	20668652
IL2RA	3559	interleukin 2 receptor, alpha	negative regulation of immune response	Biological process	-
JAM3	83700	junctional adhesion molecule 3	protein homodimerization activity	Molecular function	-
IL1RL1	9173	interleukin 1 receptor-like 1	interleukin-1 receptor activity	Molecular function	-
TSEN54	283989	TSEN54 tRNA splicing endonuclease subunit	RNA phosphodiester bond hydrolysis	Biological process	-
ATP5A1	498	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle	embryo development	Biological process	-
PCTP	58488	phosphatidylcholine transfer protein	cholesterol metabolic process	Biological process	-
PLP1	5354	proteolipid protein 1	substantia nigra development	Biological process	22926577
NRG1	3084	neuregulin 1	positive regulation of cell adhesion	Biological process	7556068
SERPINA12	145264	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12	plasma membrane	Cellular component	-
MLST8	64223	MTOR associated protein, LST8 homolog (S. cerevisiae)	positive regulation of TOR signaling	Biological process	15467718
SOCS1	8651	suppressor of cytokine signaling 1	insulin-like growth factor receptor binding	Molecular function	9727029
DSG2	1829	desmoglein 2	programmed cell death	Biological process	-
MAST2	23139	microtubule associated serine/threonine kinase 2	ATP binding	Molecular function	-
PGK2	5232	phosphoglycerate kinase 2	activation of mitophagy in response to mitochondrial depolarization	Biological process	22020285
P2RX5	5026	purinergic receptor P2X, ligand gated ion channel, 5	transmembrane signaling receptor activity	Molecular function	9414125
TECR	9524	trans-2,3-enoyl-CoA reductase	nucleus	Cellular component	21630459
DMRT3	58524	doublesex and mab-3 related transcription factor 3	nucleus	Cellular component	-
TLR9	54106	toll-like receptor 9	endosome	Cellular component	-
EEF2K	29904	eukaryotic elongation factor 2 kinase	translational elongation	Biological process	9144159
TIAM1	7074	T-cell lymphoma invasion and metastasis 1	axon guidance	Biological process	-
POLR2C	5432	polymerase (RNA) II (DNA directed) polypeptide C, 33kDa	transcription-coupled nucleotide-excision repair	Biological process	-
ZFPM1	161882	zinc finger protein, FOG family member 1	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	Molecular function	15920471
SENP1	29843	SUMO1/sentrin specific peptidase 1	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
MDH1	4190	malate dehydrogenase 1, NAD (soluble)	activation of mitophagy in response to mitochondrial depolarization	Biological process	22020285
ABL1	25	ABL proto-oncogene 1, non-receptor tyrosine kinase	regulation of cell proliferation	Biological process	-
SNAI2	6591	snail family zinc finger 2	chromatin binding	Molecular function	-
CCL21	6366	chemokine (C-C motif) ligand 21	extracellular region	Cellular component	-
RBMX	27316	RNA binding motif protein, X-linked	protein binding	Molecular function	12165565
NUPL1	9818	nucleoporin like 1	cellular response to heat	Biological process	-
ANKRA2	57763	ankyrin repeat, family A (RFXANK-like), 2	nucleus	Cellular component	-
ANGPT1	284	angiopoietin 1	microvillus	Cellular component	19424712
OR2AJ1	127608	olfactory receptor, family 2, subfamily AJ, member 1	olfactory receptor activity	Molecular function	-
OGDH	4967	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)	generation of precursor metabolites and energy	Biological process	-
IL4R	3566	interleukin 4 receptor	positive regulation of T-helper 2 cell differentiation	Biological process	-
PLRG1	5356	pleiotropic regulator 1	catalytic step 2 spliceosome	Cellular component	11991638
CMTM8	152189	CKLF-like MARVEL transmembrane domain containing 8	chemotaxis	Biological process	-
GAP43	2596	growth associated protein 43	axon choice point recognition	Biological process	-
TBC1D8B	54885	TBC1 domain family, member 8B (with GRAM domain)	positive regulation of GTPase activity	Biological process	-
CCL5	6352	chemokine (C-C motif) ligand 5	protein binding	Molecular function	23480650
WAS	7454	Wiskott-Aldrich syndrome	endosomal transport	Biological process	-
CDRT15L2	256223	CMT1A duplicated region transcript 15-like 2	integral component of membrane	Cellular component	-
NEXN	91624	nexilin (F actin binding protein)	Z disc	Cellular component	-
DDX17	10521	DEAD (Asp-Glu-Ala-Asp) box helicase 17	protein binding	Molecular function	-
GJA1	2697	gap junction protein, alpha 1, 43kDa	negative regulation of endothelial cell proliferation	Biological process	-
CRISPLD2	83716	cysteine-rich secretory protein LCCL domain containing 2	lung development	Biological process	-
TCF24	100129654	transcription factor 24	nucleus	Cellular component	-
HCLS1	3059	hematopoietic cell-specific Lyn substrate 1	intracellular signal transduction	Biological process	8978766
FOSB	2354	FBJ murine osteosarcoma viral oncogene homolog B	sequence-specific DNA binding transcription factor activity	Molecular function	-
BMX	660	BMX non-receptor tyrosine kinase	B cell receptor signaling pathway	Biological process	-
ZP1	22917	zona pellucida glycoprotein 1 (sperm receptor)	binding of sperm to zona pellucida	Biological process	-
USP10	9100	ubiquitin specific peptidase 10	regulation of proteasomal protein catabolic process	Biological process	-
OR2T29	343563	olfactory receptor, family 2, subfamily T, member 29	integral component of membrane	Cellular component	-
MSTN	2660	myostatin	skeletal muscle atrophy	Biological process	-
SFRP2	6423	secreted frizzled-related protein 2	patterning of blood vessels	Biological process	-
PTCH1	5727	patched 1	limb morphogenesis	Biological process	8681379
PARP1	142	poly (ADP-ribose) polymerase 1	NAD binding	Molecular function	-
PTEN	5728	phosphatase and tensin homolog	response to glucose	Biological process	-
NDUFA6	4700	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa	NADH dehydrogenase (ubiquinone) activity	Molecular function	9878551
AQP1	358	aquaporin 1 (Colton blood group)	renal water homeostasis	Biological process	-
CLIC5	53405	chloride intracellular channel 5	extracellular exosome	Cellular component	19056867
ZNF32	7580	zinc finger protein 32	regulation of transcription, DNA-templated	Biological process	-
LARS	51520	leucyl-tRNA synthetase	cytoplasm	Cellular component	-
SOX11	6664	SRY (sex determining region Y)-box 11	positive regulation of gene expression	Biological process	19808959
RDX	5962	radixin	lamellipodium	Cellular component	-
PLSCR5	389158	phospholipid scramblase family, member 5	phospholipid scrambling	Biological process	-
CNOT2	4848	CCR4-NOT transcription complex, subunit 2	RNA phosphodiester bond hydrolysis, exonucleolytic	Biological process	21299754
NOS1	4842	nitric oxide synthase 1 (neuronal)	myoblast fusion	Biological process	7545544
ATAT1	79969	alpha tubulin acetyltransferase 1	coated pit	Cellular component	-
ITGA3	3675	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	growth cone	Cellular component	-
USP32	84669	ubiquitin specific peptidase 32	ubiquitin-specific protease activity	Molecular function	-
SMAD4	4089	SMAD family member 4	regulation of binding	Biological process	-
AGFG1	3267	ArfGAP with FG repeats 1	GTPase activator activity	Molecular function	-
ITGB1BP2	26548	integrin beta 1 binding protein (melusin) 2	muscle organ development	Biological process	10506186
LIMD1	8994	LIM domains containing 1	cytoplasmic mRNA processing body	Cellular component	20616046
GSTA1	2938	glutathione S-transferase alpha 1	xenobiotic metabolic process	Biological process	-
ATP1B1	481	ATPase, Na+/K+ transporting, beta 1 polypeptide	intercalated disc	Cellular component	-
PIM1	5292	Pim-1 proto-oncogene, serine/threonine kinase	hyaluronan metabolic process	Biological process	-
NLGN4X	57502	neuroligin 4, X-linked	cerebellum development	Biological process	18227507
LMLN	89782	leishmanolysin-like (metallopeptidase M8 family)	lipid particle	Cellular component	-
CRABP2	1382	cellular retinoic acid binding protein 2	transport	Biological process	-
C2CD5	9847	C2 calcium-dependent domain containing 5	cellular response to insulin stimulus	Biological process	21907143
SLC11A2	4891	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2	zinc ion transmembrane transporter activity	Molecular function	17109629
ICE2	79664	interactor of little elongation complex ELL subunit 2	snRNA transcription from RNA polymerase II promoter	Biological process	23932780
MAPKAPK5	8550	mitogen-activated protein kinase-activated protein kinase 5	negative regulation of TOR signaling	Biological process	-
RBM5	10181	RNA binding motif protein 5	RNA binding	Molecular function	10352938
FBXO9	26268	F-box protein 9	cytoplasm	Cellular component	23263282
NPPB	4879	natriuretic peptide B	regulation of vascular permeability	Biological process	14737067
POU3F3	5455	POU class 3 homeobox 3	nucleus	Cellular component	-
GTF2F1	2962	general transcription factor IIF, polypeptide 1, 74kDa	transcription coactivator activity	Molecular function	7854423
SIX3	6496	SIX homeobox 3	RNA polymerase II distal enhancer sequence-specific DNA binding	Molecular function	-
BMPR1A	657	bone morphogenetic protein receptor, type IA	SMAD binding	Molecular function	12065756
PGD	5226	phosphogluconate dehydrogenase	NADP binding	Molecular function	-
CSGALNACT2	55454	chondroitin sulfate N-acetylgalactosaminyltransferase 2	chondroitin sulfate proteoglycan biosynthetic process	Biological process	11788602
POLR2B	5431	polymerase (RNA) II (DNA directed) polypeptide B, 140kDa	somatic stem cell maintenance	Biological process	-
KLK14	43847	kallikrein-related peptidase 14	serine-type endopeptidase activity	Molecular function	10969073
IGHM	3507	immunoglobulin heavy constant mu	phosphatidylcholine binding	Molecular function	21786026
TPM1	7168	tropomyosin 1 (alpha)	wound healing	Biological process	17721995
C3orf58	205428	chromosome 3 open reading frame 58	Golgi membrane	Cellular component	18651652
HIF1A	3091	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	neural crest cell migration	Biological process	-
SLC26A1	10861	solute carrier family 26 (anion exchanger), member 1	integral component of plasma membrane	Cellular component	-
AP2M1	1173	adaptor-related protein complex 2, mu 1 subunit	epidermal growth factor receptor signaling pathway	Biological process	-
BLOC1S3	388552	biogenesis of lysosomal organelles complex-1, subunit 3	membrane organization	Biological process	-
ZBTB4	57659	zinc finger and BTB domain containing 4	protein homodimerization activity	Molecular function	16354688
TGFB1I1	7041	transforming growth factor beta 1 induced transcript 1	zinc ion binding	Molecular function	-
ITM2C	81618	integral membrane protein 2C	ATP binding	Molecular function	-
GJA1	2697	gap junction protein, alpha 1, 43kDa	negative regulation of gene expression	Biological process	-
CACNA1A	773	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	neuronal cell body	Cellular component	-
COL18A1	80781	collagen, type XVIII, alpha 1	response to hydrostatic pressure	Biological process	-
LZTS1	11178	leucine zipper, putative tumor suppressor 1	cell cycle	Biological process	-
DNAH10	196385	dynein, axonemal, heavy chain 10	cilium	Cellular component	-
GPX3	2878	glutathione peroxidase 3	hydrogen peroxide catabolic process	Biological process	2491950
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	regulation of smooth muscle cell proliferation	Biological process	17122440
OR10K2	391107	olfactory receptor, family 10, subfamily K, member 2	olfactory receptor activity	Molecular function	-
TNFSF4	7292	tumor necrosis factor (ligand) superfamily, member 4	positive regulation of interleukin-4 production	Biological process	18501882
CEP57	9702	centrosomal protein 57kDa	microtubule anchoring	Biological process	-
GBP5	115362	guanylate binding protein 5	metabolic process	Biological process	-
HLA-C	3107	major histocompatibility complex, class I, C	interferon-gamma-mediated signaling pathway	Biological process	-
GDAP1	54332	ganglioside induced differentiation associated protein 1	protein targeting to mitochondrion	Biological process	15772096
KIF2C	11004	kinesin family member 2C	chromosome, centromeric region	Cellular component	14960279
UBE3A	7337	ubiquitin protein ligase E3A	metal ion binding	Molecular function	-
RPA2	6118	replication protein A2, 32kDa	base-excision repair	Biological process	-
ZNF518B	85460	zinc finger protein 518B	regulation of transcription from RNA polymerase II promoter	Biological process	-
OSBPL3	26031	oxysterol binding protein-like 3	lipid transport	Biological process	-
GJB1	2705	gap junction protein, beta 1, 32kDa	membrane organization	Biological process	-
RAB4A	5867	RAB4A, member RAS oncogene family	extracellular exosome	Cellular component	15326289
PDGFRB	5159	platelet-derived growth factor receptor, beta polypeptide	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway	Biological process	-
VTI1B	10490	vesicle transport through interaction with t-SNAREs 1B	cytoplasm	Cellular component	-
IL33	90865	interleukin 33	transport vesicle	Cellular component	-
NCALD	83988	neurocalcin delta	clathrin coat of trans-Golgi network vesicle	Cellular component	11964161
GART	2618	phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase	response to inorganic substance	Biological process	-
PLCD1	5333	phospholipase C, delta 1	GTPase activating protein binding	Molecular function	18434237
PITX2	5308	paired-like homeodomain 2	transcription factor complex	Cellular component	15385555
ABCA1	19	ATP-binding cassette, sub-family A (ABC1), member 1	phospholipid homeostasis	Biological process	16702602
DVL2	1856	dishevelled segment polarity protein 2	protein self-association	Molecular function	-
ADH4	127	alcohol dehydrogenase 4 (class II), pi polypeptide	all-trans retinal binding	Molecular function	15369820
PCBP2	5094	poly(rC) binding protein 2	ubiquitin protein ligase binding	Molecular function	19881509
LENG9	94059	leukocyte receptor cluster (LRC) member 9	positive regulation of defense response to virus by host	Biological process	22020285
SOX30	11063	SRY (sex determining region Y)-box 30	regulation of transcription, DNA-templated	Biological process	-
ZFP91	80829	ZFP91 zinc finger protein	ligase activity	Molecular function	-
SPTBN5	51332	spectrin, beta, non-erythrocytic 5	lysosomal transport	Biological process	23704327
ALDH1B1	219	aldehyde dehydrogenase 1 family, member B1	mitochondrial matrix	Cellular component	-
PAM	5066	peptidylglycine alpha-amidating monooxygenase	L-ascorbic acid binding	Molecular function	-
TCEB1	6921	transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	-
QIQN5815	100129033	uncharacterized LOC100129033	integral component of membrane	Cellular component	-
CAPZA1	829	capping protein (actin filament) muscle Z-line, alpha 1	blood coagulation	Biological process	-
LSM1	27257	LSM1, U6 small nuclear RNA associated	poly(A) RNA binding	Molecular function	22658674
ZBBX	79740	zinc finger, B-box domain containing	zinc ion binding	Molecular function	-
HSF2	3298	heat shock transcription factor 2	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding	Molecular function	10561509
ZNF592	9640	zinc finger protein 592	regulation of transcription, DNA-templated	Biological process	-
STMN1	3925	stathmin 1	regulation of cytoskeleton organization	Biological process	-
PTCH1	5727	patched 1	hindlimb morphogenesis	Biological process	-
ABI1	10006	abl-interactor 1	movement of cell or subcellular component	Biological process	11516653
MATN4	8785	matrilin 4	extracellular region	Cellular component	-
PTK2B	2185	protein tyrosine kinase 2 beta	negative regulation of bone mineralization	Biological process	-
AGPAT5	55326	1-acylglycerol-3-phosphate O-acyltransferase 5	protein binding	Molecular function	25416956
MMP15	4324	matrix metallopeptidase 15 (membrane-inserted)	response to estradiol	Biological process	-
MAPK14	1432	mitogen-activated protein kinase 14	p38MAPK cascade	Biological process	-
OR7G1	125962	olfactory receptor, family 7, subfamily G, member 1	plasma membrane	Cellular component	-
PEX6	5190	peroxisomal biogenesis factor 6	peroxisome organization	Biological process	8940266
TOM1L1	10040	target of myb1 (chicken)-like 1	ubiquitin binding	Molecular function	15611048
DNAH5	1767	dynein, axonemal, heavy chain 5	left/right axis specification	Biological process	-
HGFAC	3083	HGF activator	extracellular region	Cellular component	14718574
LRP6	4040	low density lipoprotein receptor-related protein 6	negative regulation of protein serine/threonine kinase activity	Biological process	19107203
CHRNA3	1136	cholinergic receptor, nicotinic, alpha 3 (neuronal)	ion transmembrane transport	Biological process	20438829
MED13	9969	mediator complex subunit 13	intracellular steroid hormone receptor signaling pathway	Biological process	11867769
RPS6KB1	6198	ribosomal protein S6 kinase, 70kDa, polypeptide 1	neuron projection	Cellular component	-
ABCG1	9619	ATP-binding cassette, sub-family G (WHITE), member 1	low-density lipoprotein particle remodeling	Biological process	16556852
HDAC2	3066	histone deacetylase 2	nucleus	Cellular component	-
POR	5447	P450 (cytochrome) oxidoreductase	cellular response to follicle-stimulating hormone stimulus	Biological process	-
CD46	4179	CD46 molecule, complement regulatory protein	positive regulation of T cell proliferation	Biological process	12540904
HIST1H3H	8357	histone cluster 1, H3h	DNA replication-dependent nucleosome assembly	Biological process	14718166
APOE	348	apolipoprotein E	extracellular region	Cellular component	-
SLC27A2	11001	solute carrier family 27 (fatty acid transporter), member 2	long-chain fatty acid-CoA ligase activity	Molecular function	10198260
TTN	7273	titin	skeletal muscle myosin thick filament assembly	Biological process	9817758
ERCC2	2068	excision repair cross-complementation group 2	bone mineralization	Biological process	-
CDK4	1019	cyclin-dependent kinase 4	nuclear membrane	Cellular component	18827403
NEDD4	4734	neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase	cellular response to UV	Biological process	17996703
CCNG1	900	cyclin G1	mitotic nuclear division	Biological process	-
FECH	2235	ferrochelatase	protoporphyrinogen IX metabolic process	Biological process	15123683
TSNAX	7257	translin-associated factor X	RNA phosphodiester bond hydrolysis, endonucleolytic	Biological process	-
ADRA2C	152	adrenoceptor alpha 2C	cytoplasm	Cellular component	16605244
NUBPL	80224	nucleotide binding protein-like	ATP binding	Molecular function	-
RFX2	5990	regulatory factor X, 2 (influences HLA class II expression)	nucleus	Cellular component	-
NLRP5	126206	NLR family, pyrin domain containing 5	embryo implantation	Biological process	-
DHX9	1660	DEAH (Asp-Glu-Ala-His) box helicase 9	osteoblast differentiation	Biological process	16210410
PIGA	5277	phosphatidylinositol glycan anchor biosynthesis, class A	integral component of membrane	Cellular component	-
PLCD4	84812	phospholipase C, delta 4	endoplasmic reticulum	Cellular component	-
RILPL2	196383	Rab interacting lysosomal protein-like 2	primary cilium	Cellular component	-
RASEF	158158	RAS and EF-hand domain containing	perinuclear region of cytoplasm	Cellular component	-
NDUFA3	4696	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa	mitochondrial respiratory chain complex I	Cellular component	9878551
DUOX2	50506	dual oxidase 2	fertilization	Biological process	-
SAC3D1	29901	SAC3 domain containing 1	protein binding	Molecular function	16239144
PRKRIR	5612	protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)	metal ion binding	Molecular function	-
DOK1	1796	docking protein 1, 62kDa (downstream of tyrosine kinase 1)	insulin receptor signaling pathway	Biological process	-
SF3B4	10262	splicing factor 3b, subunit 4, 49kDa	nucleotide binding	Molecular function	-
TOR1AIP1	26092	torsin A interacting protein 1	nuclear membrane organization	Biological process	-
AGXT	189	alanine-glyoxylate aminotransferase	glycine biosynthetic process, by transamination of glyoxylate	Biological process	22198249
DVL1	1855	dishevelled segment polarity protein 1	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Biological process	20177058
COL3A1	1281	collagen, type III, alpha 1	integrin binding	Molecular function	14970208
ZNF572	137209	zinc finger protein 572	metal ion binding	Molecular function	-
NOXO1	124056	NADPH oxidase organizer 1	identical protein binding	Molecular function	17126813
UNC13A	23025	unc-13 homolog A (C. elegans)	diacylglycerol binding	Molecular function	-
MPO	4353	myeloperoxidase	defense response to fungus	Biological process	-
MAP2K2	5605	mitogen-activated protein kinase kinase 2	vascular endothelial growth factor receptor signaling pathway	Biological process	-
IL1RN	3557	interleukin 1 receptor antagonist	intracellular	Cellular component	7629520
PBX3	5090	pre-B-cell leukemia homeobox 3	sequence-specific DNA binding transcription factor activity	Molecular function	-
SIX3	6496	SIX homeobox 3	sequence-specific DNA binding transcription factor activity	Molecular function	-
CHD4	1108	chromodomain helicase DNA binding protein 4	ATP binding	Molecular function	-
CORO1A	11151	coronin, actin binding protein, 1A	myosin heavy chain binding	Molecular function	23100250
CPAMD8	27151	C3 and PZP-like, alpha-2-macroglobulin domain containing 8	negative regulation of endopeptidase activity	Biological process	-
CBX4	8535	chromobox homolog 4	nuclear speck	Cellular component	-
RAPGEF3	10411	Rap guanine nucleotide exchange factor (GEF) 3	positive regulation of protein export from nucleus	Biological process	23867755
MED1	5469	mediator complex subunit 1	positive regulation of G0 to G1 transition	Biological process	-
COMMD1	150684	copper metabolism (Murr1) domain containing 1	recycling endosome	Cellular component	21741370
ARHGEF9	23229	Cdc42 guanine nucleotide exchange factor (GEF) 9	synaptic transmission	Biological process	-
APBB2	323	amyloid beta (A4) precursor protein-binding, family B, member 2	cytoplasm	Cellular component	-
ZFYVE28	57732	zinc finger, FYVE domain containing 28	phosphatidylinositol-3-phosphate binding	Molecular function	19460345
NUP35	129401	nucleoporin 35kDa	intermediate filament cytoskeleton	Cellular component	-
PTK2B	2185	protein tyrosine kinase 2 beta	innate immune response	Biological process	-
IFNA8	3445	interferon, alpha 8	B cell differentiation	Biological process	-
ARID3A	1820	AT rich interactive domain 3A (BRIGHT-like)	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
FOXD3	27022	forkhead box D3	double-stranded DNA binding	Molecular function	-
GPATCH2	55105	G patch domain containing 2	nucleic acid binding	Molecular function	-
TACC1	6867	transforming, acidic coiled-coil containing protein 1	cerebral cortex development	Biological process	-
PDIA4	9601	protein disulfide isomerase family A, member 4	cell surface	Cellular component	19995400
OR4Q3	441669	olfactory receptor, family 4, subfamily Q, member 3	detection of chemical stimulus involved in sensory perception	Biological process	-
SALL4	57167	spalt-like transcription factor 4	inner cell mass cell proliferation	Biological process	-
PARP9	83666	poly (ADP-ribose) polymerase family, member 9	cytoplasm	Cellular component	16809771
PRKAA1	5562	protein kinase, AMP-activated, alpha 1 catalytic subunit	negative regulation of lipid catabolic process	Biological process	-
HTR1B	3351	5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled	synaptic transmission	Biological process	-
GPER1	2852	G protein-coupled estrogen receptor 1	positive regulation of cell proliferation	Biological process	20551055
YWHAG	7532	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma	insulin-like growth factor receptor binding	Molecular function	12482592
PSMB11	122706	proteasome (prosome, macropain) subunit, beta type, 11	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	Biological process	-
PALM	5064	paralemmin	positive regulation of dendritic spine development	Biological process	-
WRN	7486	Werner syndrome, RecQ helicase-like	response to oxidative stress	Biological process	17611195
B3GAT2	135152	beta-1,3-glucuronyltransferase 2	carbohydrate metabolic process	Biological process	-
WNT7B	7477	wingless-type MMTV integration site family, member 7B	cellular response to retinoic acid	Biological process	12239632
DLG3	1741	discs, large homolog 3 (Drosophila)	nucleotide phosphorylation	Biological process	-
CALU	813	calumenin	platelet activation	Biological process	-
CD3D	915	CD3d molecule, delta (CD3-TCR complex)	alpha-beta T cell receptor complex	Cellular component	-
SERPINB7	8710	serpin peptidase inhibitor, clade B (ovalbumin), member 7	serine-type endopeptidase inhibitor activity	Molecular function	-
QSOX1	5768	quiescin Q6 sulfhydryl oxidase 1	extracellular space	Cellular component	10708601
AXIN2	8313	axin 2	I-SMAD binding	Molecular function	-
ALDH9A1	223	aldehyde dehydrogenase 9 family, member A1	4-trimethylammoniobutyraldehyde dehydrogenase activity	Molecular function	-
PPP2R5B	5526	protein phosphatase 2, regulatory subunit B', beta	protein phosphatase type 2A complex	Cellular component	-
HARS2	23438	histidyl-tRNA synthetase 2, mitochondrial	gene expression	Biological process	-
RAB1B	81876	RAB1B, member RAS oncogene family	Rab protein signal transduction	Biological process	-
TOMM6	100188893	translocase of outer mitochondrial membrane 6 homolog (yeast)	cellular protein metabolic process	Biological process	-
CCBE1	147372	collagen and calcium binding EGF domains 1	collagen trimer	Cellular component	-
BCL2L1	598	BCL2-like 1	integral component of membrane	Cellular component	-
HOXB6	3216	homeobox B6	transcription, DNA-templated	Biological process	-
MAP3K10	4294	mitogen-activated protein kinase kinase kinase 10	protein autophosphorylation	Biological process	8195146
GZMH	2999	granzyme H (cathepsin G-like 2, protein h-CCPX)	cytolysis	Biological process	-
CLTC	1213	clathrin, heavy chain (Hc)	membrane	Cellular component	16210410
SETMAR	6419	SET domain and mariner transposase fusion gene	DNA integration	Biological process	16332963
ITPR3	3710	inositol 1,4,5-trisphosphate receptor, type 3	platelet activation	Biological process	-
USP13	8975	ubiquitin specific peptidase 13 (isopeptidase T-3)	cell proliferation	Biological process	21811243
SPAG11B	10407	sperm associated antigen 11B	molecular_function	Molecular function	-
MYF5	4617	myogenic factor 5	embryonic skeletal system morphogenesis	Biological process	-
STK3	6788	serine/threonine kinase 3	negative regulation of canonical Wnt signaling pathway	Biological process	20412773
DACT3	147906	dishevelled-binding antagonist of beta-catenin 3	negative regulation of epithelial to mesenchymal transition	Biological process	-
CEP78	84131	centrosomal protein 78kDa	centrosome	Cellular component	21399614
MEGF10	84466	multiple EGF-like-domains 10	regulation of skeletal muscle tissue development	Biological process	22101682
CXCL10	3627	chemokine (C-X-C motif) ligand 10	chemokine-mediated signaling pathway	Biological process	18645041
DMRT1	1761	doublesex and mab-3 related transcription factor 1	positive regulation of male gonad development	Biological process	-
CDKN3	1033	cyclin-dependent kinase inhibitor 3	protein serine/threonine phosphatase activity	Molecular function	12745075
ENTPD7	57089	ectonucleoside triphosphate diphosphohydrolase 7	cytoplasmic vesicle membrane	Cellular component	-
NDEL1	81565	nudE neurodevelopment protein 1-like 1	regulation of intracellular protein transport	Biological process	21283621
CLYBL	171425	citrate lyase beta like	metal ion binding	Molecular function	-
FOXD2	2306	forkhead box D2	cell differentiation	Biological process	-
LYG1	129530	lysozyme G-like 1	extracellular region	Cellular component	-
KYNU	8942	kynureninase	response to vitamin B6	Biological process	1939450
WNT7A	7476	wingless-type MMTV integration site family, member 7A	cerebellar granule cell differentiation	Biological process	-
AGPAT1	10554	1-acylglycerol-3-phosphate O-acyltransferase 1	phosphatidic acid biosynthetic process	Biological process	-
RPL32	6161	ribosomal protein L32	translational elongation	Biological process	-
ARHGAP21	57584	Rho GTPase activating protein 21	Golgi apparatus	Cellular component	20525016
PYCARD	29108	PYD and CARD domain containing	cytoplasm	Cellular component	12019269
RASA3	22821	RAS p21 protein activator 3	negative regulation of Ras protein signal transduction	Biological process	-
AOAH	313	acyloxyacyl hydrolase (neutrophil)	inflammatory response	Biological process	1883828
NEK2	4751	NIMA-related kinase 2	protein kinase activity	Molecular function	24554434
CD109	135228	CD109 molecule	osteoclast fusion	Biological process	-
GATC	283459	glutamyl-tRNA(Gln) amidotransferase, subunit C	mitochondrial translation	Biological process	19805282
RPS16	6217	ribosomal protein S16	cytosolic small ribosomal subunit	Cellular component	2016298
CASP5	838	caspase 5, apoptosis-related cysteine peptidase	IPAF inflammasome complex	Cellular component	-
SLC17A8	246213	solute carrier family 17 (vesicular glutamate transporter), member 8	symporter activity	Molecular function	-
SGCG	6445	sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)	cytoskeleton	Cellular component	-
UACA	55075	uveal autoantigen with coiled-coil domains and ankyrin repeats	perinuclear region of cytoplasm	Cellular component	-
OR5AU1	390445	olfactory receptor, family 5, subfamily AU, member 1	olfactory receptor activity	Molecular function	-
H2AFB2	474381	H2A histone family, member B2	nuclear nucleosome	Cellular component	22795134
APOM	55937	apolipoprotein M	antioxidant activity	Molecular function	22204862
PON3	5446	paraoxonase 3	dephosphorylation	Biological process	-
ULK1	8408	unc-51 like autophagy activating kinase 1	regulation of autophagy	Biological process	17595159
SYT12	91683	synaptotagmin XII	calcium ion-dependent exocytosis of neurotransmitter	Biological process	-
TERT	7015	telomerase reverse transcriptase	tRNA binding	Molecular function	21937513
GMNN	51053	geminin, DNA replication inhibitor	negative regulation of DNA replication	Biological process	9635433
ZBTB48	3104	zinc finger and BTB domain containing 48	regulation of transcription, DNA-templated	Biological process	-
PPM1B	5495	protein phosphatase, Mg2+/Mn2+ dependent, 1B	peptidyl-threonine dephosphorylation	Biological process	20801214
WNT9B	7484	wingless-type MMTV integration site family, member 9B	male genitalia development	Biological process	-
DIRAS3	9077	DIRAS family, GTP-binding RAS-like 3	protein binding	Molecular function	21643014
TIMM10	26519	translocase of inner mitochondrial membrane 10 homolog (yeast)	protein transporter activity	Molecular function	-
AARS	16	alanyl-tRNA synthetase	tRNA aminoacylation for protein translation	Biological process	-
ANGPT1	284	angiopoietin 1	positive regulation of phosphatidylinositol 3-kinase signaling	Biological process	-
GTF2F1	2962	general transcription factor IIF, polypeptide 1, 74kDa	gene expression	Biological process	-
VAMP4	8674	vesicle-associated membrane protein 4	vesicle fusion	Biological process	-
GNAQ	2776	guanine nucleotide binding protein (G protein), q polypeptide	forebrain neuron development	Biological process	-
NOTCH4	4855	notch 4	protein binding	Molecular function	11101851
ZFP69B	65243	ZFP69 zinc finger protein B	DNA binding	Molecular function	-
METTL5	29081	methyltransferase like 5	methyltransferase activity	Molecular function	-
ATPIF1	93974	ATPase inhibitory factor 1	negative regulation of nucleotide metabolic process	Biological process	-
ARPC1B	10095	actin related protein 2/3 complex, subunit 1B, 41kDa	focal adhesion	Cellular component	21423176
KRT16	3868	keratin 16, type I	morphogenesis of an epithelium	Biological process	-
FOLH1	2346	folate hydrolase (prostate-specific membrane antigen) 1	membrane	Cellular component	9375657
CLCN5	1184	chloride channel, voltage-sensitive 5	regulation of anion transmembrane transport	Biological process	-
ABCA7	10347	ATP-binding cassette, sub-family A (ABC1), member 7	positive regulation of ERK1 and ERK2 cascade	Biological process	-
ZNF860	344787	zinc finger protein 860	regulation of transcription, DNA-templated	Biological process	-
ZNF625	90589	zinc finger protein 625	regulation of transcription, DNA-templated	Biological process	-
AMH	268	anti-Mullerian hormone	transforming growth factor beta receptor binding	Molecular function	-
PRKAR2A	5576	protein kinase, cAMP-dependent, regulatory, type II, alpha	protein binding	Molecular function	11278869
PI16	221476	peptidase inhibitor 16	peptidase inhibitor activity	Molecular function	-
SMAD4	4089	SMAD family member 4	positive regulation of cell proliferation involved in heart valve morphogenesis	Biological process	-
RAB11B	9230	RAB11B, member RAS oncogene family	synaptic vesicle membrane	Cellular component	-
TOPORS	10210	topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase	positive regulation of transcription, DNA-templated	Biological process	-
SUN1	23353	Sad1 and UNC84 domain containing 1	cytoskeletal anchoring at nuclear membrane	Biological process	18396275
OR2L5	81466	olfactory receptor, family 2, subfamily L, member 5	olfactory receptor activity	Molecular function	-
PARK2	5071	parkin RBR E3 ubiquitin protein ligase	protein ubiquitination	Biological process	23933751
SMS	6611	spermine synthase	cytosol	Cellular component	-
AGO4	192670	argonaute RISC catalytic component 4	micro-ribonucleoprotein complex	Cellular component	-
FOXO4	4303	forkhead box O4	anatomical structure morphogenesis	Biological process	-
PPP1R3B	79660	protein phosphatase 1, regulatory subunit 3B	intracellular membrane-bounded organelle	Cellular component	-
CYP27A1	1593	cytochrome P450, family 27, subfamily A, polypeptide 1	xenobiotic metabolic process	Biological process	-
RPLP2	6181	ribosomal protein, large, P2	viral life cycle	Biological process	-
ATP1A3	478	ATPase, Na+/K+ transporting, alpha 3 polypeptide	steroid hormone binding	Molecular function	11546672
AQP7	364	aquaporin 7	water channel activity	Molecular function	9405233
ITGB1	3688	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	metal ion binding	Molecular function	-
RPL30	6156	ribosomal protein L30	extracellular exosome	Cellular component	20458337
AKR1C2	1646	aldo-keto reductase family 1, member C2	daunorubicin metabolic process	Biological process	20837989
ZNF513	130557	zinc finger protein 513	transcription regulatory region DNA binding	Molecular function	20797688
BCKDHA	593	branched chain keto acid dehydrogenase E1, alpha polypeptide	small molecule metabolic process	Biological process	-
TBCC	6903	tubulin folding cofactor C	cytoskeleton	Cellular component	8706133
ADD2	119	adducin 2 (beta)	protein homodimerization activity	Molecular function	7642559
DKK1	22943	dickkopf WNT signaling pathway inhibitor 1	signal transducer activity	Molecular function	10383463
TIMP2	7077	TIMP metallopeptidase inhibitor 2	growth cone	Cellular component	-
RASEF	158158	RAS and EF-hand domain containing	calcium ion binding	Molecular function	-
RPS6KA1	6195	ribosomal protein S6 kinase, 90kDa, polypeptide 1	cytosol	Cellular component	-
FAM162A	26355	family with sequence similarity 162, member A	activation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	15082785
JUNB	3726	jun B proto-oncogene	response to cAMP	Biological process	-
ACER2	340485	alkaline ceramidase 2	activation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	20628055
PDS5B	23047	PDS5 cohesin associated factor B	regulation of cell proliferation	Biological process	10963680
CENPC	1060	centromere protein C	nucleosome assembly	Biological process	-
XRCC2	7516	X-ray repair complementing defective repair in Chinese hamster cells 2	double-strand break repair via homologous recombination	Biological process	23149936
CDK5	1020	cyclin-dependent kinase 5	layer formation in cerebral cortex	Biological process	-
PRKD2	25865	protein kinase D2	intracellular signal transduction	Biological process	18059339
DEPTOR	64798	DEP domain containing MTOR-interacting protein	negative regulation of cell size	Biological process	19446321
GRID1	2894	glutamate receptor, ionotropic, delta 1	ionotropic glutamate receptor signaling pathway	Biological process	-
HES7	84667	hes family bHLH transcription factor 7	regulation of somitogenesis	Biological process	-
DLG4	1742	discs, large homolog 4 (Drosophila)	receptor localization to synapse	Biological process	-
HACD1	9200	3-hydroxyacyl-CoA dehydratase 1	myotube differentiation	Biological process	-
PNKP	11284	polynucleotide kinase 3'-phosphatase	DNA 3' dephosphorylation involved in DNA repair	Biological process	-
TBXAS1	6916	thromboxane A synthase 1 (platelet)	thromboxane-A synthase activity	Molecular function	-
ROCK2	9475	Rho-associated, coiled-coil containing protein kinase 2	centrosome	Cellular component	17015463
GLI3	2737	GLI family zinc finger 3	smoothened signaling pathway involved in ventral spinal cord interneuron specification	Biological process	-
PPP1CB	5500	protein phosphatase 1, catalytic subunit, beta isozyme	PTW/PP1 phosphatase complex	Cellular component	20354225
SLC4A4	8671	solute carrier family 4 (sodium bicarbonate cotransporter), member 4	transmembrane transport	Biological process	-
SPTBN1	6711	spectrin, beta, non-erythrocytic 1	ankyrin binding	Molecular function	17620337
TGM2	7052	transglutaminase 2	positive regulation of apoptotic process	Biological process	24349085
CDC26	246184	cell division cycle 26	cell division	Biological process	-
BCL2	596	B-cell CLL/lymphoma 2	gland morphogenesis	Biological process	-
MRPL10	124995	mitochondrial ribosomal protein L10	ribonucleoprotein complex	Cellular component	-
DAZ3	57054	deleted in azoospermia 3	RNA binding	Molecular function	-
TBC1D20	128637	TBC1 domain family, member 20	ER to Golgi vesicle-mediated transport	Biological process	21680502
ADAR	103	adenosine deaminase, RNA-specific	pre-miRNA processing	Biological process	23622242
TNFAIP3	7128	tumor necrosis factor, alpha-induced protein 3	regulation of defense response to virus by host	Biological process	15142865
CCL5	6352	chemokine (C-C motif) ligand 5	chemotaxis	Biological process	1380064
SELP	6403	selectin P (granule membrane protein 140kDa, antigen CD62)	plasma membrane	Cellular component	-
SMAD9	4093	SMAD family member 9	hindbrain development	Biological process	-
LIFR	3977	leukemia inhibitory factor receptor alpha	cell surface receptor signaling pathway	Biological process	1915266
ARSJ	79642	arylsulfatase family, member J	metal ion binding	Molecular function	-
PDRG1	81572	p53 and DNA-damage regulated 1	cytoplasm	Cellular component	-
CMA1	1215	chymase 1, mast cell	angiotensin maturation	Biological process	-
NEBL	10529	nebulette	cytoskeletal protein binding	Molecular function	17987659
TRPM2	7226	transient receptor potential cation channel, subfamily M, member 2	integral component of plasma membrane	Cellular component	9806837
UTS2R	2837	urotensin 2 receptor	G-protein coupled receptor activity	Molecular function	10499587
RAMP3	10268	receptor (G protein-coupled) activity modifying protein 3	cell surface	Cellular component	10882736
TSSK1B	83942	testis-specific serine kinase 1B	protein phosphorylation	Biological process	15733851
NOG	9241	noggin	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation	Biological process	8582276
IL20	50604	interleukin 20	interleukin-22 receptor binding	Molecular function	-
MOGAT2	80168	monoacylglycerol O-acyltransferase 2	intestinal absorption	Biological process	-
NDUFA13	51079	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13	cellular metabolic process	Biological process	-
PPIB	5479	peptidylprolyl isomerase B (cyclophilin B)	protein peptidyl-prolyl isomerization	Biological process	-
TMEM252	169693	transmembrane protein 252	integral component of membrane	Cellular component	-
DCTN1	1639	dynactin 1	dynein complex	Cellular component	-
UBE2C	11065	ubiquitin-conjugating enzyme E2C	positive regulation of exit from mitosis	Biological process	9122200
GRIK4	2900	glutamate receptor, ionotropic, kainate 4	glutamate receptor signaling pathway	Biological process	8263508
XBP1	7494	X-box binding protein 1	fatty acid biosynthetic process	Biological process	22013210
NCK2	8440	NCK adaptor protein 2	epidermal growth factor receptor signaling pathway	Biological process	9737977
LINC00301	283197	long intergenic non-protein coding RNA 301	integral component of membrane	Cellular component	-
RNASE7	84659	ribonuclease, RNase A family, 7	extracellular exosome	Cellular component	23376485
DCDC5	100506627	doublecortin domain containing 5	intracellular	Cellular component	-
WNT3A	89780	wingless-type MMTV integration site family, member 3A	positive regulation of dermatome development	Biological process	10654605
GPR161	23432	G protein-coupled receptor 161	G-protein coupled amine receptor activity	Molecular function	-
OR6K3	391114	olfactory receptor, family 6, subfamily K, member 3	transmembrane signaling receptor activity	Molecular function	-
PICALM	8301	phosphatidylinositol binding clathrin assembly protein	clathrin coat of coated pit	Cellular component	10436022
TOLLIP	54472	toll interacting protein	ubiquitin conjugating enzyme binding	Molecular function	-
FLT3LG	2323	fms-related tyrosine kinase 3 ligand	positive regulation of cell proliferation	Biological process	8180375
CUTC	51076	cutC copper transporter	ion transmembrane transport	Biological process	-
TPX2	22974	TPX2, microtubule-associated	spindle pole	Cellular component	14718566
CSNK1D	1453	casein kinase 1, delta	protein phosphorylation	Biological process	16618118
AP5M1	55745	adaptor-related protein complex 5, mu 1 subunit	cytosol	Cellular component	22022230
OR2T6	254879	olfactory receptor, family 2, subfamily T, member 6	G-protein coupled receptor activity	Molecular function	-
NOTCH4	4855	notch 4	nucleoplasm	Cellular component	-
IGF2BP2	10644	insulin-like growth factor 2 mRNA binding protein 2	negative regulation of translation	Biological process	9891060
CASP1	834	caspase 1, apoptosis-related cysteine peptidase	cytoplasm	Cellular component	-
LDHB	3945	lactate dehydrogenase B	membrane	Cellular component	19946888
SP1	6667	Sp1 transcription factor	double-stranded DNA binding	Molecular function	20371611
TOLLIP	54472	toll interacting protein	inflammatory response	Biological process	10854325
JPH1	56704	junctophilin 1	Z disc	Cellular component	-
POFUT1	23509	protein O-fucosyltransferase 1	fucose metabolic process	Biological process	-
FURIN	5045	furin (paired basic amino acid cleaving enzyme)	integral component of membrane	Cellular component	-
TCF4	6925	transcription factor 4	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	8978694
PCDHB14	56122	protocadherin beta 14	synapse assembly	Biological process	12231349
GNL3	26354	guanine nucleotide binding protein-like 3 (nucleolar)	regulation of cell proliferation	Biological process	-
PSMC5	5705	proteasome (prosome, macropain) 26S subunit, ATPase, 5	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition	Biological process	-
BMP7	655	bone morphogenetic protein 7	growth	Biological process	-
CHMP2A	27243	charged multivesicular body protein 2A	viral life cycle	Biological process	-
CDK13	8621	cyclin-dependent kinase 13	phosphorylation of RNA polymerase II C-terminal domain	Biological process	20952539
STX17	55014	syntaxin 17	endoplasmic reticulum membrane	Cellular component	23217709
P2RY12	64805	purinergic receptor P2Y, G-protein coupled, 12	intrinsic component of membrane	Cellular component	12578987
KCNJ14	3770	potassium channel, inwardly rectifying subfamily J, member 14	synaptic transmission	Biological process	-
GCH1	2643	GTP cyclohydrolase 1	dopamine biosynthetic process	Biological process	16338639
GNAQ	2776	guanine nucleotide binding protein (G protein), q polypeptide	protein stabilization	Biological process	20399743
RAB7A	7879	RAB7A, member RAS oncogene family	endosome to lysosome transport	Biological process	18272684
BMPR2	659	bone morphogenetic protein receptor, type II (serine/threonine kinase)	protein binding	Molecular function	12045205
TDRKH	11022	tudor and KH domain containing	piP-body	Cellular component	-
PLRG1	5356	pleiotropic regulator 1	signal transducer activity	Molecular function	9765207
CCDC22	28952	coiled-coil domain containing 22	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	23563313
UNG	7374	uracil-DNA glycosylase	somatic recombination of immunoglobulin gene segments	Biological process	-
RABGEF1	27342	RAB guanine nucleotide exchange factor (GEF) 1	negative regulation of protein phosphorylation	Biological process	-
LANCL3	347404	LanC lantibiotic synthetase component C-like 3 (bacterial)	catalytic activity	Molecular function	-
NFE2L2	4780	nuclear factor, erythroid 2-like 2	protein ubiquitination	Biological process	15983046
OR52W1	120787	olfactory receptor, family 52, subfamily W, member 1	plasma membrane	Cellular component	-
MRPS15	64960	mitochondrial ribosomal protein S15	mitochondrion	Cellular component	-
AQP2	359	aquaporin 2 (collecting duct)	aging	Biological process	-
ZRANB2	9406	zinc finger, RAN-binding domain containing 2	poly(A) RNA binding	Molecular function	22658674
NUPL2	11097	nucleoporin like 2	transmembrane transport	Biological process	-
ASIC3	9311	acid sensing (proton gated) ion channel 3	transmembrane transport	Biological process	-
ZNF219	51222	zinc finger protein 219	transcription, DNA-templated	Biological process	14621294
PRKD2	25865	protein kinase D2	ATP binding	Molecular function	-
YWHAB	7529	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta	hippo signaling	Biological process	-
IRX1	79192	iroquois homeobox 1	sequence-specific DNA binding	Molecular function	-
IL15	3600	interleukin 15	membrane	Cellular component	10851076
SNTB1	6641	syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)	muscle contraction	Biological process	8183929
OLIG2	10215	oligodendrocyte lineage transcription factor 2	protein homodimerization activity	Molecular function	-
RBPJ	3516	recombination signal binding protein for immunoglobulin kappa J region	positive regulation of cardiac muscle cell proliferation	Biological process	-
ZBTB47	92999	zinc finger and BTB domain containing 47	DNA binding	Molecular function	-
HSPB1	3315	heat shock 27kDa protein 1	cytoskeleton	Cellular component	16130169
MYH6	4624	myosin, heavy chain 6, cardiac muscle, alpha	ATP binding	Molecular function	-
SMAD4	4089	SMAD family member 4	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
FGF9	2254	fibroblast growth factor 9	lung-associated mesenchyme development	Biological process	-
TNS1	7145	tensin 1	cytoskeleton	Cellular component	-
BAX	581	BCL2-associated X protein	positive regulation of apoptotic process involved in mammary gland involution	Biological process	-
TFRC	7037	transferrin receptor	cytoplasmic membrane-bounded vesicle	Cellular component	15229288
CCNB3	85417	cyclin B3	nucleoplasm	Cellular component	-
SRGAP2	23380	SLIT-ROBO Rho GTPase activating protein 2	postsynaptic density	Cellular component	-
ARNTL2	56938	aryl hydrocarbon receptor nuclear translocator-like 2	circadian rhythm	Biological process	10864977
NOTCH3	4854	notch 3	Notch signaling pathway	Biological process	-
PUS10	150962	pseudouridylate synthase 10	pseudouridine synthase activity	Molecular function	-
DYNC2H1	79659	dynein, cytoplasmic 2, heavy chain 1	ATPase activity	Molecular function	-
CALCA	796	calcitonin-related polypeptide alpha	negative regulation of blood pressure	Biological process	10642343
TNFRSF10A	8797	tumor necrosis factor receptor superfamily, member 10a	plasma membrane	Cellular component	-
OAS1	4938	2'-5'-oligoadenylate synthetase 1, 40/46kDa	glucose metabolic process	Biological process	23575436
PRPF4	9128	pre-mRNA processing factor 4	nuclear speck	Cellular component	-
SNX10	29887	sorting nexin 10	osteoclast differentiation	Biological process	-
LIPF	8513	lipase, gastric	malate dehydrogenase activity	Molecular function	-
OR4M1	441670	olfactory receptor, family 4, subfamily M, member 1	G-protein coupled receptor activity	Molecular function	-
TERF2	7014	telomeric repeat binding factor 2	protein binding	Molecular function	10984620
RXRA	6256	retinoid X receptor, alpha	gene expression	Biological process	-
G3BP1	10146	GTPase activating protein (SH3 domain) binding protein 1	endonuclease activity	Molecular function	-
JUN	3725	jun proto-oncogene	monocyte differentiation	Biological process	-
MT1B	4490	metallothionein 1B	negative regulation of growth	Biological process	-
DCK	1633	deoxycytidine kinase	ATP binding	Molecular function	-
PDE1B	5153	phosphodiesterase 1B, calmodulin-dependent	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity	Molecular function	-
ARG1	383	arginase 1	cellular response to glucagon stimulus	Biological process	-
FOXP2	93986	forkhead box P2	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
SNCA	6622	synuclein, alpha (non A4 component of amyloid precursor)	behavioral response to cocaine	Biological process	-
ICA1	3382	islet cell autoantigen 1, 69kDa	transport vesicle membrane	Cellular component	-
TUBA1C	84790	tubulin, alpha 1c	cytoskeleton-dependent intracellular transport	Biological process	12090300
CREB3L3	84699	cAMP responsive element binding protein 3-like 3	integral component of membrane	Cellular component	-
POLR3D	661	polymerase (RNA) III (DNA directed) polypeptide D, 44kDa	positive regulation of type I interferon production	Biological process	-
EGF	1950	epidermal growth factor	positive regulation of epidermal growth factor-activated receptor activity	Biological process	9712850
TRAF6	7189	TNF receptor-associated factor 6, E3 ubiquitin protein ligase	osteoclast differentiation	Biological process	-
FLT3	2322	fms-related tyrosine kinase 3	protein homodimerization activity	Molecular function	19549778
JPH2	57158	junctophilin 2	protein binding	Molecular function	20095964
FER	2241	fer (fps/fes related) tyrosine kinase	diapedesis	Biological process	-
SLC29A2	3177	solute carrier family 29 (equilibrative nucleoside transporter), member 2	transmembrane transport	Biological process	-
BMP2	650	bone morphogenetic protein 2	transforming growth factor beta receptor binding	Molecular function	-
AKNA	80709	AT-hook transcription factor	transcription, DNA-templated	Biological process	-
PARP4	143	poly (ADP-ribose) polymerase family, member 4	cellular response to DNA damage stimulus	Biological process	10477748
OSTC	58505	oligosaccharyltransferase complex subunit (non-catalytic)	integral component of membrane	Cellular component	-
DUT	1854	deoxyuridine triphosphatase	nucleobase-containing small molecule metabolic process	Biological process	-
PLA2G1B	5319	phospholipase A2, group IB (pancreas)	secretory granule	Cellular component	-
JOSD2	126119	Josephin domain containing 2	omega peptidase activity	Molecular function	-
KCNH4	23415	potassium channel, voltage gated eag related subfamily H, member 4	integral component of plasma membrane	Cellular component	-
HOXA10	3206	homeobox A10	male gonad development	Biological process	-
STARD9	57519	StAR-related lipid transfer (START) domain containing 9	nucleus	Cellular component	22153075
SIRT1	23411	sirtuin 1	cellular response to tumor necrosis factor	Biological process	15152190
NME1	4830	NME/NM23 nucleoside diphosphate kinase 1	perinuclear region of cytoplasm	Cellular component	-
PKN2	5586	protein kinase N2	protein kinase activity	Molecular function	7851406
RAB25	57111	RAB25, member RAS oncogene family	pseudopodium	Cellular component	17925226
CTSB	1508	cathepsin B	mitochondrion	Cellular component	-
PRRC2A	7916	proline-rich coiled-coil 2A	cytoplasm	Cellular component	-
PAGR1	79447	PAXIP1 associated glutamate-rich protein 1	nucleus	Cellular component	17500065
SOCS5	9655	suppressor of cytokine signaling 5	cytokine-mediated signaling pathway	Biological process	-
LIF	3976	leukemia inhibitory factor	positive regulation of protein localization to nucleus	Biological process	22783022
SULT1A3	6818	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3	catecholamine metabolic process	Biological process	-
CLPP	8192	caseinolytic mitochondrial matrix peptidase proteolytic subunit	identical protein binding	Molecular function	-
CCDC92	80212	coiled-coil domain containing 92	protein binding	Molecular function	22458338
RBM4	5936	RNA binding motif protein 4	IRES-dependent translational initiation	Biological process	17284590
CACNA1H	8912	calcium channel, voltage-dependent, T type, alpha 1H subunit	myoblast fusion	Biological process	10861024
MED13	9969	mediator complex subunit 13	membrane	Cellular component	19946888
ITGB1BP1	9270	integrin beta 1 binding protein 1	cellular response to vascular endothelial growth factor stimulus	Biological process	20616313
EIF2AK2	5610	eukaryotic translation initiation factor 2-alpha kinase 2	modulation by virus of host morphology or physiology	Biological process	-
TAC1	6863	tachykinin, precursor 1	response to lipopolysaccharide	Biological process	-
TMEM187	8269	transmembrane protein 187	molecular_function	Molecular function	-
NTRK2	4915	neurotrophic tyrosine kinase, receptor, type 2	glutamate secretion	Biological process	-
CLOCK	9575	clock circadian regulator	positive regulation of NF-kappaB transcription factor activity	Biological process	-
TUBA1B	10376	tubulin, alpha 1b	double-stranded RNA binding	Molecular function	21266579
PMEL	6490	premelanosome protein	multivesicular body membrane	Cellular component	11694580
RRP8	23378	ribosomal RNA processing 8, methyltransferase, homolog (yeast)	nucleoplasm	Cellular component	-
KIF14	9928	kinesin family member 14	cerebellar cortex development	Biological process	-
FAM57A	79850	family with sequence similarity 57, member A	plasma membrane	Cellular component	-
ACADVL	37	acyl-CoA dehydrogenase, very long chain	temperature homeostasis	Biological process	-
PIM1	5292	Pim-1 proto-oncogene, serine/threonine kinase	manganese ion binding	Molecular function	1825810
ID1	3397	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	negative regulation of transcription, DNA-templated	Biological process	15138269
BCAP31	10134	B-cell receptor-associated protein 31	positive regulation of ER-associated ubiquitin-dependent protein catabolic process	Biological process	18555783
EGFR	1956	epidermal growth factor receptor	cellular response to mechanical stimulus	Biological process	-
NDFIP1	80762	Nedd4 family interacting protein 1	regulation of myeloid leukocyte differentiation	Biological process	-
ATP2C1	27032	ATPase, Ca++ transporting, type 2C, member 1	epidermis development	Biological process	10615129
DIRAS2	54769	DIRAS family, GTP-binding RAS-like 2	intracellular	Cellular component	-
SELP	6403	selectin P (granule membrane protein 140kDa, antigen CD62)	leukocyte tethering or rolling	Biological process	-
RB1	5925	retinoblastoma 1	phosphoprotein binding	Molecular function	16360038
CD86	942	CD86 molecule	fibroblast growth factor receptor signaling pathway	Biological process	-
KCNU1	157855	potassium channel, subfamily U, member 1	sperm-egg recognition	Biological process	-
HCRTR1	3061	hypocretin (orexin) receptor 1	response to peptide	Biological process	-
HIST1H2AC	8334	histone cluster 1, H2ac	negative regulation of cell proliferation	Biological process	23956221
PLA2G2D	26279	phospholipase A2, group IID	phosphatidic acid biosynthetic process	Biological process	-
MYOG	4656	myogenin (myogenic factor 4)	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
PBX1	5087	pre-B-cell leukemia homeobox 1	DNA binding	Molecular function	10052460
OPTN	10133	optineurin	protein binding	Molecular function	15837803
NEURL1	9148	neuralized E3 ubiquitin protein ligase 1	perikaryon	Cellular component	-
GAS7	8522	growth arrest-specific 7	actin filament binding	Molecular function	-
SRGAP2B	647135	SLIT-ROBO Rho GTPase activating protein 2B	nervous system development	Biological process	-
PLA2G6	8398	phospholipase A2, group VI (cytosolic, calcium-independent)	positive regulation of vasodilation	Biological process	-
NXPH3	11248	neurexophilin 3	molecular_function	Molecular function	-
APH1A	51107	APH1A gamma secretase subunit	Notch receptor processing	Biological process	15274632
LUC7L3	51747	LUC7-like 3 (S. cerevisiae)	U1 snRNP	Cellular component	-
ADIPOQ	9370	adiponectin, C1Q and collagen domain containing	response to glucocorticoid	Biological process	-
HTT	3064	huntingtin	late endosome	Cellular component	17704510
CXCL12	6387	chemokine (C-X-C motif) ligand 12	negative regulation of leukocyte apoptotic process	Biological process	15059845
HDAC4	9759	histone deacetylase 4	Z disc	Cellular component	-
UCKL1	54963	uridine-cytidine kinase 1-like 1	cytoplasm	Cellular component	-
NEU4	129807	sialidase 4	glycoprotein catabolic process	Biological process	15213228
PTPRR	5801	protein tyrosine phosphatase, receptor type, R	protein tyrosine phosphatase activity	Molecular function	7836467
CKAP5	9793	cytoskeleton associated protein 5	gamma-tubulin complex	Cellular component	14718566
EIF5A2	56648	eukaryotic translation initiation factor 5A2	mRNA transport	Biological process	-
ARHGEF7	8874	Rho guanine nucleotide exchange factor (GEF) 7	focal adhesion	Cellular component	21423176
TOR1B	27348	torsin family 1, member B (torsin B)	ATPase activity	Molecular function	20015956
WNT1	7471	wingless-type MMTV integration site family, member 1	cytoplasm	Cellular component	11793365
UBA52	7311	ubiquitin A-52 residue ribosomal protein fusion product 1	negative regulation of type I interferon production	Biological process	-
OR2T1	26696	olfactory receptor, family 2, subfamily T, member 1	G-protein coupled receptor signaling pathway	Biological process	-
CRISPLD2	83716	cysteine-rich secretory protein LCCL domain containing 2	heparin binding	Molecular function	-
SLC8B1	80024	solute carrier family 8 (sodium/lithium/calcium exchanger), member B1	ion transport	Biological process	-
SMAD3	4088	SMAD family member 3	paraxial mesoderm morphogenesis	Biological process	-
GPR52	9293	G protein-coupled receptor 52	G-protein coupled amine receptor activity	Molecular function	-
MAPK3	5595	mitogen-activated protein kinase 3	Fc-gamma receptor signaling pathway involved in phagocytosis	Biological process	-
RNF17	56163	ring finger protein 17	zinc ion binding	Molecular function	-
NQO1	1728	NAD(P)H dehydrogenase, quinone 1	oxidation-reduction process	Biological process	-
SOST	50964	sclerostin	extracellular space	Cellular component	-
TBP	6908	TATA box binding protein	termination of RNA polymerase I transcription	Biological process	-
DLG2	1740	discs, large homolog 2 (Drosophila)	kinase binding	Molecular function	21119615
RAC1	5879	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	ephrin receptor signaling pathway	Biological process	-
KCNIP3	30818	Kv channel interacting protein 3, calsenilin	sensory perception of pain	Biological process	-
KIF13A	63971	kinesin family member 13A	melanosome organization	Biological process	19841138
MAP3K7	6885	mitogen-activated protein kinase kinase kinase 7	positive regulation of NF-kappaB transcription factor activity	Biological process	-
ATP6AP1	537	ATPase, H+ transporting, lysosomal accessory protein 1	proton-transporting V-type ATPase, V1 domain	Cellular component	-
NOX1	27035	NADPH oxidase 1	invadopodium membrane	Cellular component	19755710
GRM5	2915	glutamate receptor, metabotropic 5	dendritic spine	Cellular component	-
UBA52	7311	ubiquitin A-52 residue ribosomal protein fusion product 1	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
CHD7	55636	chromodomain helicase DNA binding protein 7	olfactory behavior	Biological process	-
ID2	3398	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	natural killer cell differentiation	Biological process	-
VPS37B	79720	vacuolar protein sorting 37 homolog B (S. cerevisiae)	viral process	Biological process	-
TRIM21	6737	tripartite motif containing 21	positive regulation of sequence-specific DNA binding transcription factor activity	Biological process	23077300
ONECUT2	9480	one cut homeobox 2	positive regulation of cell migration	Biological process	-
TNFRSF17	608	tumor necrosis factor receptor superfamily, member 17	immune system process	Biological process	-
MRPL55	128308	mitochondrial ribosomal protein L55	mitochondrial translational initiation	Biological process	-
TERT	7015	telomerase reverse transcriptase	nucleoplasm	Cellular component	-
CTBP1	1487	C-terminal binding protein 1	Golgi organization	Biological process	-
MUC3A	4584	mucin 3A, cell surface associated	Golgi lumen	Cellular component	-
PACSIN2	11252	protein kinase C and casein kinase substrate in neurons 2	intracellular membrane-bounded organelle	Cellular component	-
NECAP1	25977	NECAP endocytosis associated 1	plasma membrane	Cellular component	-
VSNL1	7447	visinin-like 1	intracellular	Cellular component	-
IRX5	10265	iroquois homeobox 5	visual perception	Biological process	-
PRDM16	63976	PR domain containing 16	transcription coactivator activity	Molecular function	-
RTN4	57142	reticulon 4	endoplasmic reticulum tubular network organization	Biological process	18779370
GK	2710	glycerol kinase	triglyceride metabolic process	Biological process	8651297
PZP	5858	pregnancy-zone protein	extracellular region	Cellular component	14718574
EI24	9538	etoposide induced 2.4	intrinsic apoptotic signaling pathway in response to DNA damage	Biological process	-
GPR158	57512	G protein-coupled receptor 158	regulation of G-protein coupled receptor protein signaling pathway	Biological process	-
PSMB1	5689	proteasome (prosome, macropain) subunit, beta type, 1	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	Biological process	-
CLCA2	9635	chloride channel accessory 2	plasma membrane	Cellular component	-
AFAP1L2	84632	actin filament associated protein 1-like 2	positive regulation of protein tyrosine kinase activity	Biological process	17412687
ZNF701	55762	zinc finger protein 701	nucleus	Cellular component	-
CPNE3	8895	copine III	lipid metabolic process	Biological process	9430674
SLC30A7	148867	solute carrier family 30 (zinc transporter), member 7	zinc II ion transport	Biological process	-
EDA2R	60401	ectodysplasin A2 receptor	intracellular	Cellular component	-
EREG	2069	epiregulin	extracellular region	Cellular component	-
ARTN	9048	artemin	neuroblast proliferation	Biological process	9883723
PDAP1	11333	PDGFA associated protein 1	cell proliferation	Biological process	8780057
HAAO	23498	3-hydroxyanthranilate 3,4-dioxygenase	3-hydroxyanthranilate 3,4-dioxygenase activity	Molecular function	-
DHODH	1723	dihydroorotate dehydrogenase (quinone)	positive regulation of apoptotic process	Biological process	-
DAXX	1616	death-domain associated protein	receptor signaling protein activity	Molecular function	9215629
IRAK1	3654	interleukin-1 receptor-associated kinase 1	negative regulation of apoptotic process	Biological process	-
DLX6	1750	distal-less homeobox 6	anatomical structure formation involved in morphogenesis	Biological process	-
FGF5	2250	fibroblast growth factor 5	phosphatidylinositol-mediated signaling	Biological process	-
BMPR2	659	bone morphogenetic protein receptor, type II (serine/threonine kinase)	spanning component of plasma membrane	Cellular component	9442116
FOXH1	8928	forkhead box H1	nucleus	Cellular component	16120611
NUP43	348995	nucleoporin 43kDa	cellular protein metabolic process	Biological process	-
MESP1	55897	mesoderm posterior basic helix-loop-helix transcription factor 1	cardioblast migration to the midline involved in heart field formation	Biological process	-
PSMB7	5695	proteasome (prosome, macropain) subunit, beta type, 7	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological process	-
SCGB1A1	7356	secretoglobin, family 1A, member 1 (uteroglobin)	rough endoplasmic reticulum	Cellular component	-
RAC1	5879	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	apoptotic signaling pathway	Biological process	-
WNT2B	7482	wingless-type MMTV integration site family, member 2B	chondrocyte differentiation	Biological process	15135146
TRPT1	83707	tRNA phosphotransferase 1	regulation of protein kinase activity	Biological process	-
OPTN	10133	optineurin	Golgi ribbon formation	Biological process	15837803
SFRP1	6422	secreted frizzled-related protein 1	frizzled binding	Molecular function	10347172
NPLOC4	55666	nuclear protein localization 4 homolog (S. cerevisiae)	error-free translesion synthesis	Biological process	-
FADD	8772	Fas (TNFRSF6)-associated via death domain	neuron projection	Cellular component	-
PI16	221476	peptidase inhibitor 16	negative regulation of peptidase activity	Biological process	-
SMAD2	4087	SMAD family member 2	primary miRNA processing	Biological process	19018011
NELFE	7936	negative elongation factor complex member E	RNA binding	Molecular function	2119325
TAS2R20	259295	taste receptor, type 2, member 20	integral component of membrane	Cellular component	-
IGSF1	3547	immunoglobulin superfamily, member 1	regulation of transcription, DNA-templated	Biological process	11266516
SALL1	6299	spalt-like transcription factor 1	heart development	Biological process	11484202
SH3PXD2B	285590	SH3 and PX domains 2B	phosphatidylinositol-5-phosphate binding	Molecular function	-
GALNT3	2591	polypeptide N-acetylgalactosaminyltransferase 3	calcium ion binding	Molecular function	9295285
NUDT3	11165	nudix (nucleoside diphosphate linked moiety X)-type motif 3	inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity	Molecular function	-
SULF1	23213	sulfatase 1	Golgi stack	Cellular component	-
CYP26B1	56603	cytochrome P450, family 26, subfamily B, polypeptide 1	positive regulation of gene expression	Biological process	-
PDGFRB	5159	platelet-derived growth factor receptor, beta polypeptide	wound healing	Biological process	-
PIGO	84720	phosphatidylinositol glycan anchor biosynthesis, class O	mannose-ethanolamine phosphotransferase activity	Molecular function	-
PDGFRA	5156	platelet-derived growth factor receptor, alpha polypeptide	vascular endothelial growth factor binding	Molecular function	17470632
CPT1B	1375	carnitine palmitoyltransferase 1B (muscle)	mitochondrial outer membrane	Cellular component	-
WBP2NL	164684	WBP2 N-terminal like	WW domain binding	Molecular function	17289678
RARG	5916	retinoic acid receptor, gamma	steroid hormone mediated signaling pathway	Biological process	-
EXOSC2	23404	exosome component 2	nucleolus	Cellular component	-
NIPBL	25836	Nipped-B homolog (Drosophila)	cellular response to X-ray	Biological process	17468178
PATZ1	23598	POZ (BTB) and AT hook containing zinc finger 1	negative regulation of transcription, DNA-templated	Biological process	10713105
HECW2	57520	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	-
RPTOR	57521	regulatory associated protein of MTOR, complex 1	neuronal cell body	Cellular component	-
RAP2B	5912	RAP2B, member of RAS oncogene family	membrane raft	Cellular component	18582561
EZH1	2145	enhancer of zeste 1 polycomb repressive complex 2 subunit	ESC/E(Z) complex	Cellular component	20075857
GRIPAP1	56850	GRIP1 associated protein 1	biological_process	Biological process	-
CYP19A1	1588	cytochrome P450, family 19, subfamily A, polypeptide 1	small molecule metabolic process	Biological process	-
RABGEF1	27342	RAB guanine nucleotide exchange factor (GEF) 1	zinc ion binding	Molecular function	-
TOE1	114034	target of EGR1, member 1 (nuclear)	nucleus	Cellular component	-
DIAPH1	1729	diaphanous-related formin 1	regulation of microtubule-based process	Biological process	20937854
ORMDL1	94101	ORMDL sphingolipid biosynthesis regulator 1	integral component of membrane	Cellular component	-
TRPC5	7224	transient receptor potential cation channel, subfamily C, member 5	transmembrane transport	Biological process	-
PAFAH1B1	5048	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	microtubule cytoskeleton organization	Biological process	10729324
HIST1H4E	8367	histone cluster 1, H4e	DNA replication-independent nucleosome assembly	Biological process	14718166
NT5C3A	51251	5'-nucleotidase, cytosolic IIIA	small molecule metabolic process	Biological process	-
VAMP4	8674	vesicle-associated membrane protein 4	cell surface	Cellular component	21151919
MPP5	64398	membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)	cell junction assembly	Biological process	-
OR8B4	283162	olfactory receptor, family 8, subfamily B, member 4 (gene/pseudogene)	plasma membrane	Cellular component	-
PRRX2	51450	paired related homeobox 2	artery morphogenesis	Biological process	-
MRPL35	51318	mitochondrial ribosomal protein L35	mitochondrial translational termination	Biological process	-
SRI	6717	sorcin	calcium ion transport	Biological process	-
ISL1	3670	ISL LIM homeobox 1	outflow tract morphogenesis	Biological process	-
PRKCA	5578	protein kinase C, alpha	positive regulation of lipopolysaccharide-mediated signaling pathway	Biological process	9830023
RFC1	5981	replication factor C (activator 1) 1, 145kDa	DNA binding	Molecular function	-
CD52	1043	CD52 molecule	membrane	Cellular component	1711975
RAP2C	57826	RAP2C, member of RAS oncogene family	extracellular exosome	Cellular component	19056867
MGLL	11343	monoglyceride lipase	small molecule metabolic process	Biological process	-
LSP1	4046	lymphocyte-specific protein 1	extracellular exosome	Cellular component	20458337
COPZ2	51226	coatomer protein complex, subunit zeta 2	endoplasmic reticulum-Golgi intermediate compartment membrane	Cellular component	-
ATF6B	1388	activating transcription factor 6 beta	Golgi apparatus	Cellular component	22013210
POLD2	5425	polymerase (DNA directed), delta 2, accessory subunit	nucleotide-excision repair	Biological process	-
NQO1	1728	NAD(P)H dehydrogenase, quinone 1	response to estradiol	Biological process	-
CAMK2A	815	calcium/calmodulin-dependent protein kinase II alpha	ATP binding	Molecular function	-
CDK2	1017	cyclin-dependent kinase 2	endosome	Cellular component	21262353
EIF3J	8669	eukaryotic translation initiation factor 3, subunit J	cellular protein metabolic process	Biological process	-
ERCC6	2074	excision repair cross-complementation group 6	transcription-coupled nucleotide-excision repair	Biological process	-
YWHAB	7529	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta	protein targeting	Biological process	-
ALX1	8092	ALX homeobox 1	RNA polymerase II regulatory region sequence-specific DNA binding	Molecular function	9753625
SLC25A12	8604	solute carrier family 25 (aspartate/glutamate carrier), member 12	mitochondrial inner membrane	Cellular component	-
ACYP2	98	acylphosphatase 2, muscle type	phosphate-containing compound metabolic process	Biological process	8268218
APOE	348	apolipoprotein E	aging	Biological process	-
PPP2CA	5515	protein phosphatase 2, catalytic subunit, alpha isozyme	protein dephosphorylation	Biological process	11007961
DCAF17	80067	DDB1 and CUL4 associated factor 17	Cul4-RING E3 ubiquitin ligase complex	Cellular component	16949367
POU5F1	5460	POU class 5 homeobox 1	BMP signaling pathway involved in heart induction	Biological process	19736317
SPHK1	8877	sphingosine kinase 1	protein folding	Biological process	-
ABCB8	11194	ATP-binding cassette, sub-family B (MDR/TAP), member 8	mitochondrial inner membrane	Cellular component	-
ARG1	383	arginase 1	cellular response to dexamethasone stimulus	Biological process	-
VPS16	64601	vacuolar protein sorting 16 homolog (S. cerevisiae)	late endosome membrane	Cellular component	-
ARHGEF18	23370	Rho/Rac guanine nucleotide exchange factor (GEF) 18	positive regulation of apoptotic process	Biological process	-
CCL2	6347	chemokine (C-C motif) ligand 2	cell surface receptor signaling pathway	Biological process	9548499
SFRP5	6425	secreted frizzled-related protein 5	digestive tract morphogenesis	Biological process	-
KCNK4	50801	potassium channel, two pore domain subfamily K, member 4	regulation of ion transmembrane transport	Biological process	-
SLC33A1	9197	solute carrier family 33 (acetyl-CoA transporter), member 1	endoplasmic reticulum membrane	Cellular component	-
TNR	7143	tenascin R	associative learning	Biological process	-
PEX19	5824	peroxisomal biogenesis factor 19	brush border membrane	Cellular component	-
DRD1	1812	dopamine receptor D1	positive regulation of synaptic transmission, glutamatergic	Biological process	-
EWSR1	2130	EWS RNA-binding protein 1	identical protein binding	Molecular function	21988832
PA2G4	5036	proliferation-associated 2G4, 38kDa	cell cycle arrest	Biological process	7556453
B4GALNT2	124872	beta-1,4-N-acetyl-galactosaminyl transferase 2	acetylgalactosaminyltransferase activity	Molecular function	12678917
URGCP	55665	upregulator of cell proliferation	GTP binding	Molecular function	-
PRKCG	5582	protein kinase C, gamma	positive regulation of mismatch repair	Biological process	15808853
HBB	3043	hemoglobin, beta	oxygen transport	Biological process	1540659
MAPK9	5601	mitogen-activated protein kinase 9	cellular response to tumor necrosis factor	Biological process	-
IDUA	3425	iduronidase, alpha-L-	carbohydrate metabolic process	Biological process	-
AVP	551	arginine vasopressin	positive regulation of cell growth	Biological process	-
KCNA4	3739	potassium channel, voltage gated shaker related subfamily A, member 4	integral component of membrane	Cellular component	-
ANG	283	angiogenin, ribonuclease, RNase A family, 5	oocyte maturation	Biological process	11438326
TRAF4	9618	TNF receptor-associated factor 4	protein binding	Molecular function	10514511
CYP27B1	1594	cytochrome P450, family 27, subfamily B, polypeptide 1	positive regulation of keratinocyte differentiation	Biological process	12496369
PTP4A2	8073	protein tyrosine phosphatase type IVA, member 2	extracellular exosome	Cellular component	23376485
FECH	2235	ferrochelatase	ferrous iron binding	Molecular function	1729699
TRPV4	59341	transient receptor potential cation channel, subfamily V, member 4	protein binding	Molecular function	16293632
PTN	5764	pleiotrophin	learning	Biological process	-
SEC11A	23478	SEC11 homolog A (S. cerevisiae)	signal peptide processing	Biological process	-
NCOA1	8648	nuclear receptor coactivator 1	hippocampus development	Biological process	-
SYT11	23208	synaptotagmin XI	integral component of plasma membrane	Cellular component	-
CALCA	796	calcitonin-related polypeptide alpha	cell-cell signaling	Biological process	2408883
NRIP2	83714	nuclear receptor interacting protein 2	transcription, DNA-templated	Biological process	-
PINX1	54984	PIN2/TERF1 interacting, telomerase inhibitor 1	mitotic metaphase plate congression	Biological process	19393617
ACTA1	58	actin, alpha 1, skeletal muscle	muscle filament sliding	Biological process	-
ESCO2	157570	establishment of sister chromatid cohesion N-acetyltransferase 2	site of double-strand break	Cellular component	-
IRX3	79191	iroquois homeobox 3	sequence-specific DNA binding	Molecular function	-
DLD	1738	dihydrolipoamide dehydrogenase	nucleoplasm	Cellular component	-
TULP3	7289	tubby like protein 3	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning	Biological process	-
PDCD5	9141	programmed cell death 5	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	16374546
SCYL2	55681	SCY1-like 2 (S. cerevisiae)	positive regulation of receptor internalization	Biological process	19643732
B4GALT4	8702	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4	keratan sulfate biosynthetic process	Biological process	-
DDB2	1643	damage-specific DNA binding protein 2, 48kDa	protein complex	Cellular component	12732143
CXCL3	2921	chemokine (C-X-C motif) ligand 3	extracellular region	Cellular component	-
COQ6	51004	coenzyme Q6 monooxygenase	Golgi apparatus	Cellular component	-
P2RX7	5027	purinergic receptor P2X, ligand gated ion channel, 7	response to fluid shear stress	Biological process	-
CYP11A1	1583	cytochrome P450, family 11, subfamily A, polypeptide 1	phenol-containing compound metabolic process	Biological process	-
MYOCD	93649	myocardin	positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation	Biological process	15907818
GPD1L	23171	glycerol-3-phosphate dehydrogenase 1-like	sodium channel regulator activity	Molecular function	17967977
UBE2V2	7336	ubiquitin-conjugating enzyme E2 variant 2	positive regulation of neuron projection development	Biological process	-
HLA-DRB3	3125	major histocompatibility complex, class II, DR beta 3	detection of bacterium	Biological process	22321387
PNPT1	87178	polyribonucleotide nucleotidyltransferase 1	mitochondrial mRNA catabolic process	Biological process	20691904
PRKCDBP	112464	protein kinase C, delta binding protein	protein kinase C binding	Molecular function	-
HEATR1	55127	HEAT repeat containing 1	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Biological process	-
SLC25A10	1468	solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10	mitochondrial inner membrane	Cellular component	-
FOXC2	2303	forkhead box C2	blood vessel remodeling	Biological process	-
ROCK1	6093	Rho-associated, coiled-coil containing protein kinase 1	leukocyte tethering or rolling	Biological process	12082081
UBAC2	337867	UBA domain containing 2	protein binding	Molecular function	25416956
MAPT	4137	microtubule-associated protein tau	positive regulation of microtubule polymerization	Biological process	1421571
CYP2B6	1555	cytochrome P450, family 2, subfamily B, polypeptide 6	small molecule metabolic process	Biological process	-
IMPA1	3612	inositol(myo)-1(or 4)-monophosphatase 1	inositol monophosphate 3-phosphatase activity	Molecular function	-
PROL1	58503	proline rich, lacrimal 1	retina homeostasis	Biological process	23580065
KCTD13	253980	potassium channel tetramerization domain containing 13	protein ubiquitination	Biological process	-
AJUBA	84962	ajuba LIM protein	regulation of cell migration	Biological process	-
NFKB1	4790	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	cellular response to peptide hormone stimulus	Biological process	22357537
LRRC8D	55144	leucine rich repeat containing 8 family, member D	ion transport	Biological process	-
AURKA	6790	aurora kinase A	regulation of protein stability	Biological process	15987997
KIF5B	3799	kinesin family member 5B	ciliary rootlet	Cellular component	-
SPAG5	10615	sperm associated antigen 5	cytoplasm	Cellular component	-
SUN2	25777	Sad1 and UNC84 domain containing 2	nuclear membrane	Cellular component	-
FGR	2268	FGR proto-oncogene, Src family tyrosine kinase	mitochondrial inner membrane	Cellular component	-
SLCO1B3	28234	solute carrier organic anion transporter family, member 1B3	basolateral plasma membrane	Cellular component	-
FUT8	2530	fucosyltransferase 8 (alpha (1,6) fucosyltransferase)	N-glycan processing	Biological process	11698403
SCRIB	23513	scribbled planar cell polarity protein	cell-cell junction	Cellular component	15649318
MAPK10	5602	mitogen-activated protein kinase 10	protein binding	Molecular function	19527717
CHRM3	1131	cholinergic receptor, muscarinic 3	small molecule metabolic process	Biological process	-
CPEB4	80315	cytoplasmic polyadenylation element binding protein 4	poly(A) RNA binding	Molecular function	22658674
ARHGDIB	397	Rho GDP dissociation inhibitor (GDI) beta	movement of cell or subcellular component	Biological process	16130169
LRRTM2	26045	leucine rich repeat transmembrane neuronal 2	excitatory synapse	Cellular component	-
HDAC2	3066	histone deacetylase 2	transcription factor complex	Cellular component	-
DNPH1	10591	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	nucleoside deoxyribosyltransferase activity	Molecular function	-
MRPS18B	28973	mitochondrial ribosomal protein S18B	mitochondrial translational termination	Biological process	-
ALAD	210	aminolevulinate dehydratase	catalytic activity	Molecular function	2063868
IGHV2-70	28454	immunoglobulin heavy variable 2-70	antigen binding	Molecular function	5449120
FTH1	2495	ferritin, heavy polypeptide 1	intracellular ferritin complex	Cellular component	6589621
GJD2	57369	gap junction protein, delta 2, 36kDa	action potential	Biological process	-
LIF	3976	leukemia inhibitory factor	trophoblast giant cell differentiation	Biological process	-
RAB1A	5861	RAB1A, member RAS oncogene family	Rab protein signal transduction	Biological process	-
MSLN	10232	mesothelin	membrane	Cellular component	8552591
OTX2	5015	orthodenticle homeobox 2	primitive streak formation	Biological process	-
CSF1R	1436	colony stimulating factor 1 receptor	intracellular	Cellular component	-
KCNA7	3743	potassium channel, voltage gated shaker related subfamily A, member 7	plasma membrane	Cellular component	-
ARHGAP35	2909	Rho GTPase activating protein 35	camera-type eye development	Biological process	-
YEATS2	55689	YEATS domain containing 2	histone H3 acetylation	Biological process	18838386
GUCY1B3	2983	guanylate cyclase 1, soluble, beta 3	cytoplasm	Cellular component	-
HDAC3	8841	histone deacetylase 3	chromatin binding	Molecular function	16569215
ZNF780B	163131	zinc finger protein 780B	sequence-specific DNA binding transcription factor activity	Molecular function	-
IPO8	10526	importin 8	protein binding	Molecular function	17932509
SP110	3431	SP110 nuclear body protein	nucleus	Cellular component	-
JAK1	3716	Janus kinase 1	cytoplasm	Cellular component	10502458
HSPA1L	3305	heat shock 70kDa protein 1-like	ATP binding	Molecular function	-
ATCAY	85300	ataxia, cerebellar, Cayman type	dendrite	Cellular component	-
CLCF1	23529	cardiotrophin-like cytokine factor 1	cell surface receptor signaling pathway	Biological process	-
FGD5	152273	FYVE, RhoGEF and PH domain containing 5	metal ion binding	Molecular function	-
HOXD1	3231	homeobox D1	transcription, DNA-templated	Biological process	-
ZNF705B	100132396	zinc finger protein 705B	nucleus	Cellular component	-
MAP2K3	5606	mitogen-activated protein kinase kinase 3	TRIF-dependent toll-like receptor signaling pathway	Biological process	-
APOE	348	apolipoprotein E	extrinsic component of external side of plasma membrane	Cellular component	-
FBXO4	26272	F-box protein 4	protein polyubiquitination	Biological process	16275645
KDM2A	22992	lysine (K)-specific demethylase 2A	nucleus	Cellular component	-
PRMT5	10419	protein arginine methyltransferase 5	methyltransferase activity	Molecular function	15369763
SPTAN1	6709	spectrin, alpha, non-erythrocytic 1	lateral plasma membrane	Cellular component	-
HOXC6	3223	homeobox C6	sequence-specific DNA binding	Molecular function	-
GSAP	54103	gamma-secretase activating protein	trans-Golgi network	Cellular component	20811458
ACAA1	30	acetyl-CoA acyltransferase 1	protein binding	Molecular function	18281296
TGFBI	7045	transforming growth factor, beta-induced, 68kDa	trans-Golgi network	Cellular component	19478074
VEGFA	7422	vascular endothelial growth factor A	platelet activation	Biological process	-
RBM24	221662	RNA binding motif protein 24	nucleotide binding	Molecular function	-
PCDH8	5100	protocadherin 8	plasma membrane	Cellular component	9787079
UMODL1	89766	uromodulin-like 1	regulation of apoptotic process	Biological process	-
ERVK-10	100616101	endogenous retrovirus group K, member 10	biological_process	Biological process	-
AGPS	8540	alkylglycerone phosphate synthase	peroxisomal matrix	Cellular component	-
FABP5	2171	fatty acid binding protein 5 (psoriasis-associated)	cytosol	Cellular component	-
RAB3D	9545	RAB3D, member RAS oncogene family	secretory granule membrane	Cellular component	-
PPAPDC3	84814	phosphatidic acid phosphatase type 2 domain containing 3	negative regulation of myotube differentiation	Biological process	-
B3GALT1	8708	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1	Golgi membrane	Cellular component	-
AGRN	375790	agrin	neuromuscular junction development	Biological process	-
RPSA	3921	ribosomal protein SA	translational termination	Biological process	-
SCRIB	23513	scribbled planar cell polarity protein	plasma membrane	Cellular component	16611247
LIN28B	389421	lin-28 homolog B (C. elegans)	regulation of transcription, DNA-templated	Biological process	-
LEP	3952	leptin	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
HHIP	64399	hedgehog interacting protein	smoothened signaling pathway	Biological process	-
PABPN1	8106	poly(A) binding protein, nuclear 1	muscle contraction	Biological process	9462747
RELA	5970	v-rel avian reticuloendotheliosis viral oncogene homolog A	response to amino acid	Biological process	-
IL20RB	53833	interleukin 20 receptor beta	negative regulation of type IV hypersensitivity	Biological process	-
ENPEP	2028	glutamyl aminopeptidase (aminopeptidase A)	angiogenesis	Biological process	-
SLC22A3	6581	solute carrier family 22 (organic cation transporter), member 3	activation of mitophagy in response to mitochondrial depolarization	Biological process	22020285
DUSP1	1843	dual specificity phosphatase 1	negative regulation of apoptotic process	Biological process	-
HPGD	3248	hydroxyprostaglandin dehydrogenase 15-(NAD)	NAD+ binding	Molecular function	16828555
HBEGF	1839	heparin-binding EGF-like growth factor	positive regulation of wound healing	Biological process	17655843
CTRB2	440387	chymotrypsinogen B2	digestion	Biological process	-
HBEGF	1839	heparin-binding EGF-like growth factor	positive regulation of cell growth	Biological process	-
SEMA3A	10371	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	axon extension involved in axon guidance	Biological process	-
ICAM1	3383	intercellular adhesion molecule 1	cellular response to alkaloid	Biological process	-
APOF	319	apolipoprotein F	lipid transporter activity	Molecular function	6816269
PHIP	55023	pleckstrin homology domain interacting protein	regulation of cell morphogenesis	Biological process	21834987
AKAP13	11214	A kinase (PRKA) anchor protein 13	Rho GTPase binding	Molecular function	-
ALAS2	212	5'-aminolevulinate synthase 2	protein binding	Molecular function	10727444
ECI2	10455	enoyl-CoA delta isomerase 2	metabolic process	Biological process	-
RSAD2	91543	radical S-adenosyl methionine domain containing 2	type I interferon signaling pathway	Biological process	-
NEFL	4747	neurofilament, light polypeptide	cytoplasm	Cellular component	-
RNF168	165918	ring finger protein 168, E3 ubiquitin protein ligase	protein binding	Molecular function	19203578
PPP3CA	5530	protein phosphatase 3, catalytic subunit, alpha isozyme	calcineurin complex	Cellular component	8392375
TUBA4A	7277	tubulin, alpha 4a	protein polymerization	Biological process	-
KDM2A	22992	lysine (K)-specific demethylase 2A	histone H3-K36 demethylation	Biological process	20417597
DIAPH1	1729	diaphanous-related formin 1	neuron projection	Cellular component	-
CBY1	25776	chibby homolog 1 (Drosophila)	nuclear speck	Cellular component	-
GUCA2A	2980	guanylate cyclase activator 2A (guanylin)	guanylate cyclase activator activity	Molecular function	8095028
AHCTF1	25909	AT hook containing transcription factor 1	sequence-specific DNA binding transcription factor activity	Molecular function	-
ACVR2B	93	activin A receptor, type IIB	protein binding	Molecular function	11266516
BFSP1	631	beaded filament structural protein 1, filensin	mitochondrion	Cellular component	-
MFSD5	84975	major facilitator superfamily domain containing 5	molybdate ion transmembrane transporter activity	Molecular function	-
GALK1	2584	galactokinase 1	membrane	Cellular component	8908517
MBNL1	4154	muscleblind-like splicing regulator 1	nucleus	Cellular component	-
MAPK1	5594	mitogen-activated protein kinase 1	phosphotyrosine binding	Molecular function	-
SEZ6	124925	seizure related 6 homolog (mouse)	negative regulation of dendrite development	Biological process	-
SMPD2	6610	sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)	small molecule metabolic process	Biological process	-
RNF168	165918	ring finger protein 168, E3 ubiquitin protein ligase	ubiquitin binding	Molecular function	19203578
FEZ1	9638	fasciculation and elongation protein zeta 1 (zygin I)	gamma-tubulin binding	Molecular function	-
UQCRC2	7385	ubiquinol-cytochrome c reductase core protein II	oxidative phosphorylation	Biological process	8288258
MAD1L1	8379	MAD1 mitotic arrest deficient-like 1 (yeast)	mitotic cell cycle	Biological process	-
MECOM	2122	MDS1 and EVI1 complex locus	sequence-specific DNA binding transcription factor activity	Molecular function	8643684
BCL11B	64919	B-cell CLL/lymphoma 11B (zinc finger protein)	negative regulation of apoptotic process	Biological process	-
DDX1	1653	DEAD (Asp-Glu-Ala-Asp) box helicase 1	multicellular organismal development	Biological process	7689221
TACR1	6869	tachykinin receptor 1	positive regulation of ossification	Biological process	-
ZC3H10	84872	zinc finger CCCH-type containing 10	metal ion binding	Molecular function	-
NPTX1	4884	neuronal pentraxin I	cellular response to glucose stimulus	Biological process	-
IL12B	3593	interleukin 12B	protein heterodimerization activity	Molecular function	11023671
EIF4A3	9775	eukaryotic translation initiation factor 4A3	nuclear speck	Cellular component	-
FLNA	2316	filamin A, alpha	adenylate cyclase-inhibiting dopamine receptor signaling pathway	Biological process	10692483
OXA1L	5018	oxidase (cytochrome c) assembly 1-like	oxidation-reduction process	Biological process	9247084
NR1H2	7376	nuclear receptor subfamily 1, group H, member 2	DNA binding	Molecular function	7926814
LRRFIP1	9208	leucine rich repeat (in FLII) interacting protein 1	negative regulation of transcription, DNA-templated	Biological process	9705290
MEF2C	4208	myocyte enhancer factor 2C	regulation of synaptic plasticity	Biological process	-
NLRP6	171389	NLR family, pyrin domain containing 6	cytoplasm	Cellular component	-
PRPF4	9128	pre-mRNA processing factor 4	RNA splicing	Biological process	-
PKM	5315	pyruvate kinase, muscle	poly(A) RNA binding	Molecular function	22658674
GBA3	57733	glucosidase, beta, acid 3 (gene/pseudogene)	glycosylceramidase activity	Molecular function	17595169
SP100	6672	SP100 nuclear antigen	transcription factor binding	Molecular function	11909962
TGFBR2	7048	transforming growth factor, beta receptor II (70/80kDa)	vasculogenesis	Biological process	-
NKX3-1	4824	NK3 homeobox 1	positive regulation of transcription from RNA polymerase II promoter	Biological process	19797053
ADAL	161823	adenosine deaminase-like	purine-containing compound salvage	Biological process	-
BLZF1	8548	basic leucine zipper nuclear factor 1	regulation of cell growth	Biological process	9129147
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	gastrulation with mouth forming second	Biological process	-
SEMA4D	10507	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	receptor activity	Molecular function	15613544
BCL2	596	B-cell CLL/lymphoma 2	neuron apoptotic process	Biological process	16167175
USHBP1	83878	Usher syndrome 1C binding protein 1	PDZ domain binding	Molecular function	11311560
PTPN6	5777	protein tyrosine phosphatase, non-receptor type 6	negative regulation of peptidyl-tyrosine phosphorylation	Biological process	19749791
FGGY	55277	FGGY carbohydrate kinase domain containing	kinase activity	Molecular function	-
IFNW1	3467	interferon, omega 1	cytokine receptor binding	Molecular function	1647209
HNRNPU	3192	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	CRD-mediated mRNA stability complex	Cellular component	19029303
PATL1	219988	protein associated with topoisomerase II homolog 1 (yeast)	cytosol	Cellular component	-
CDIP1	29965	cell death-inducing p53 target 1	apoptotic process	Biological process	17599062
GAL	51083	galanin/GMAP prepropeptide	extracellular space	Cellular component	9402244
CDK5	1020	cyclin-dependent kinase 5	behavioral response to cocaine	Biological process	-
RARS2	57038	arginyl-tRNA synthetase 2, mitochondrial	tRNA aminoacylation for protein translation	Biological process	-
DXO	1797	decapping exoribonuclease	cytoplasm	Cellular component	-
PLCG1	5335	phospholipase C, gamma 1	in utero embryonic development	Biological process	-
PPP2R1B	5519	protein phosphatase 2, regulatory subunit A, beta	protein binding	Molecular function	16456541
RAD21L1	642636	RAD21-like 1 (S. pombe)	fertilization	Biological process	-
PTPRE	5791	protein tyrosine phosphatase, receptor type, E	regulation of mast cell activation	Biological process	-
CCR9	10803	chemokine (C-C motif) receptor 9	immune response	Biological process	-
ERBB3	2065	erb-b2 receptor tyrosine kinase 3	epidermal growth factor receptor signaling pathway	Biological process	-
RPA1	6117	replication protein A1, 70kDa	DNA repair	Biological process	-
RAB35	11021	RAB35, member RAS oncogene family	metabolic process	Biological process	7811277
RYBP	23429	RING1 and YY1 binding protein	histone H2A monoubiquitination	Biological process	16943429
INSL3	3640	insulin-like 3 (Leydig cell)	positive regulation of cAMP biosynthetic process	Biological process	-
CLSTN3	9746	calsyntenin 3	postsynaptic membrane	Cellular component	-
ZIC2	7546	Zic family member 2	negative regulation of transcription, DNA-templated	Biological process	-
POU2F2	5452	POU class 2 homeobox 2	humoral immune response	Biological process	9442393
OAZ1	4946	ornithine decarboxylase antizyme 1	protein binding	Molecular function	17900240
HIF1A	3091	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	positive regulation of transcription from RNA polymerase II promoter	Biological process	17981124
MAPK6	5597	mitogen-activated protein kinase 6	cell cycle	Biological process	-
TRAPPC8	22878	trafficking protein particle complex 8	protein localization to pre-autophagosomal structure	Biological process	-
SYTL5	94122	synaptotagmin-like 5	synaptic vesicle exocytosis	Biological process	-
TMBIM4	51643	transmembrane BAX inhibitor motif containing 4	Golgi stack	Cellular component	17319741
ELOVL5	60481	ELOVL fatty acid elongase 5	dendrite	Cellular component	-
CTTNBP2NL	55917	CTTNBP2 N-terminal like	cytoplasm	Cellular component	-
VAMP2	6844	vesicle-associated membrane protein 2 (synaptobrevin 2)	positive regulation of intracellular protein transport	Biological process	-
ATP7B	540	ATPase, Cu++ transporting, beta polypeptide	copper ion import	Biological process	16472602
SHANK1	50944	SH3 and multiple ankyrin repeat domains 1	identical protein binding	Molecular function	-
PRKAG1	5571	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	cytosol	Cellular component	-
ARHGAP11B	89839	Rho GTPase activating protein 11B	GTPase activator activity	Molecular function	25721503
ILK	3611	integrin-linked kinase	sarcomere	Cellular component	-
BCL9L	283149	B-cell CLL/lymphoma 9-like	negative regulation of transforming growth factor beta receptor signaling pathway	Biological process	19328798
LALBA	3906	lactalbumin, alpha-	lactose biosynthetic process	Biological process	-
SLC13A5	284111	solute carrier family 13 (sodium-dependent citrate transporter), member 5	integral component of membrane	Cellular component	-
ZFYVE1	53349	zinc finger, FYVE domain containing 1	protein binding	Molecular function	19389623
CEP126	57562	centrosomal protein 126kDa	cytoplasmic microtubule organization	Biological process	24867236
TMEM233	387890	transmembrane protein 233	integral component of membrane	Cellular component	-
AZGP1	563	alpha-2-glycoprotein 1, zinc-binding	cell adhesion	Biological process	-
AQP1	358	aquaporin 1 (Colton blood group)	renal water transport	Biological process	9096382
ULK1	8408	unc-51 like autophagy activating kinase 1	cytosol	Cellular component	11146101
TICAM2	353376	toll-like receptor adaptor molecule 2	positive regulation of interferon-gamma production	Biological process	-
PLCG1	5335	phospholipase C, gamma 1	epidermal growth factor receptor signaling pathway	Biological process	-
CYP4F3	4051	cytochrome P450, family 4, subfamily F, polypeptide 3	icosanoid metabolic process	Biological process	-
OR8K5	219453	olfactory receptor, family 8, subfamily K, member 5	odorant binding	Molecular function	-
SCN2A	6326	sodium channel, voltage gated, type II alpha subunit	T-tubule	Cellular component	-
PCDHGA10	56106	protocadherin gamma subfamily A, 10	calcium ion binding	Molecular function	-
CAMK2A	815	calcium/calmodulin-dependent protein kinase II alpha	response to ischemia	Biological process	-
VANGL2	57216	VANGL planar cell polarity protein 2	regulation of actin cytoskeleton organization	Biological process	-
CNGB1	1258	cyclic nucleotide gated channel beta 1	ligand-gated ion channel activity	Molecular function	7682292
ELAC2	60528	elaC ribonuclease Z 2	mitochondrial tRNA 3'-trailer cleavage, endonucleolytic	Biological process	21593607
ZNF781	163115	zinc finger protein 781	metal ion binding	Molecular function	-
ERCC1	2067	excision repair cross-complementation group 1	nucleotide-excision repair, DNA incision, 3'-to lesion	Biological process	7657672
TNF	7124	tumor necrosis factor	cell surface receptor signaling pathway	Biological process	-
PDPN	10630	podoplanin	filopodium	Cellular component	-
PRAMEF15	653619	PRAME family member 15	negative regulation of retinoic acid receptor signaling pathway	Biological process	-
SEC61A1	29927	Sec61 alpha 1 subunit (S. cerevisiae)	membrane	Cellular component	22375059
ZNF512	84450	zinc finger protein 512	nucleus	Cellular component	-
HIST1H3J	8356	histone cluster 1, H3j	histone binding	Molecular function	20498094
GNAT2	2780	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2	photoreceptor outer segment	Cellular component	-
CXXC5	51523	CXXC finger protein 5	protein binding	Molecular function	23303788
PHTF1	10745	putative homeodomain transcription factor 1	DNA binding	Molecular function	-
MIB2	142678	mindbomb E3 ubiquitin protein ligase 2	ubiquitin-protein transferase activity	Molecular function	-
HIP1R	9026	huntingtin interacting protein 1 related	apoptotic process	Biological process	-
ACTC1	70	actin, alpha, cardiac muscle 1	actomyosin, actin portion	Cellular component	16611632
ST8SIA4	7903	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	sialylation	Biological process	-
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	cell cortex	Cellular component	19038973
OFD1	8481	oral-facial-digital syndrome 1	cilium	Cellular component	20230748
RPL4	6124	ribosomal protein L4	focal adhesion	Cellular component	21423176
PRMT8	56341	protein arginine methyltransferase 8	protein binding	Molecular function	16051612
IL24	11009	interleukin 24	negative regulation of cell migration	Biological process	-
EDN1	1906	endothelin 1	response to lipopolysaccharide	Biological process	-
HSP90AA1	3320	heat shock protein 90kDa alpha (cytosolic), class A member 1	extracellular matrix	Cellular component	-
MAPK14	1432	mitogen-activated protein kinase 14	intracellular signal transduction	Biological process	10838079
BCAS3	54828	breast carcinoma amplified sequence 3	acetyltransferase activator activity	Molecular function	17505058
NHP2L1	4809	NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)	RNA splicing	Biological process	-
KRT2	3849	keratin 2, type II	keratinocyte migration	Biological process	15737202
OR5H1	26341	olfactory receptor, family 5, subfamily H, member 1	sensory perception of smell	Biological process	-
ALDOA	226	aldolase A, fructose-bisphosphate	protein binding	Molecular function	20849852
CXCL5	6374	chemokine (C-X-C motif) ligand 5	chemokine activity	Molecular function	-
COX14	84987	COX14 cytochrome c oxidase assembly factor	mitochondrial membrane	Cellular component	-
TIAM2	26230	T-cell lymphoma invasion and metastasis 2	small molecule metabolic process	Biological process	-
ITGA4	3676	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	plasma membrane	Cellular component	-
WNT11	7481	wingless-type MMTV integration site family, member 11	cloacal septation	Biological process	9757009
NELL1	4745	NEL-like 1 (chicken)	cytoplasm	Cellular component	21723284
CD86	942	CD86 molecule	cell-cell signaling	Biological process	9915850
COX7A2	1347	cytochrome c oxidase subunit VIIa polypeptide 2 (liver)	hydrogen ion transmembrane transport	Biological process	-
PRKAA2	5563	protein kinase, AMP-activated, alpha 2 catalytic subunit	small molecule metabolic process	Biological process	-
MAN1A1	4121	mannosidase, alpha, class 1A, member 1	mannosidase activity	Molecular function	8223597
GNB1L	54584	guanine nucleotide binding protein (G protein), beta polypeptide 1-like	social behavior	Biological process	-
GSTM2	2946	glutathione S-transferase mu 2 (muscle)	protein homodimerization activity	Molecular function	8373352
SIGLEC1	6614	sialic acid binding Ig-like lectin 1, sialoadhesin	integral component of membrane	Cellular component	11133773
PSMB8	5696	proteasome (prosome, macropain) subunit, beta type, 8	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	Biological process	-
SSRP1	6749	structure specific recognition protein 1	chromatin remodeling	Biological process	-
FGF18	8817	fibroblast growth factor 18	nervous system development	Biological process	-
MCL1	4170	myeloid cell leukemia 1	cellular homeostasis	Biological process	10837489
RPL15	6138	ribosomal protein L15	poly(A) RNA binding	Molecular function	22658674
BCL2L11	10018	BCL2-like 11 (apoptosis facilitator)	developmental pigmentation	Biological process	-
LSM7	51690	LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	Biological process	-
SOD2	6648	superoxide dismutase 2, mitochondrial	positive regulation of nitric oxide biosynthetic process	Biological process	-
MLLT4-AS1	653483	MLLT4 antisense RNA 1 (head to head)	biological_process	Biological process	-
PTPN7	5778	protein tyrosine phosphatase, non-receptor type 7	cytoskeleton	Cellular component	-
PLEK	5341	pleckstrin	regulation of cell diameter	Biological process	10995449
AVPR1A	552	arginine vasopressin receptor 1A	grooming behavior	Biological process	-
TGM2	7052	transglutaminase 2	endoplasmic reticulum	Cellular component	24349085
NDUFAF7	55471	NADH dehydrogenase (ubiquinone) complex I, assembly factor 7	methylation	Biological process	20406883
CACNA1E	777	calcium channel, voltage-dependent, R type, alpha 1E subunit	voltage-gated calcium channel complex	Cellular component	-
TAS2R42	353164	taste receptor, type 2, member 42	integral component of membrane	Cellular component	20022913
BMPR1A	657	bone morphogenetic protein receptor, type IA	mesoderm formation	Biological process	-
ADAMTS13	11093	ADAM metallopeptidase with thrombospondin type 1 motif, 13	metallopeptidase activity	Molecular function	11557746
ZNF184	7738	zinc finger protein 184	DNA binding	Molecular function	-
MSRB2	22921	methionine sulfoxide reductase B2	protein repair	Biological process	14699060
P3H1	64175	prolyl 3-hydroxylase 1	extracellular exosome	Cellular component	19056867
PTPRJ	5795	protein tyrosine phosphatase, receptor type, J	platelet-derived growth factor receptor signaling pathway	Biological process	21091576
CIAO1	9391	cytosolic iron-sulfur assembly component 1	CIA complex	Cellular component	22678361
ATP7A	538	ATPase, Cu++ transporting, alpha polypeptide	blood vessel development	Biological process	-
BAG6	7917	BCL2-associated athanogene 6	intracellular membrane-bounded organelle	Cellular component	-
CAV3	859	caveolin 3	neuromuscular junction	Cellular component	-
AP3B1	8546	adaptor-related protein complex 3, beta 1 subunit	anterograde axon cargo transport	Biological process	-
SMAD2	4087	SMAD family member 2	gene expression	Biological process	-
TPP1	1200	tripeptidyl peptidase I	central nervous system development	Biological process	-
DTL	51514	denticleless E3 ubiquitin protein ligase homolog (Drosophila)	DNA damage response, detection of DNA damage	Biological process	-
NMB	4828	neuromedin B	positive regulation of cell proliferation	Biological process	-
ASPH	444	aspartate beta-hydroxylase	endoplasmic reticulum membrane	Cellular component	11007777
PLOD3	8985	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3	L-ascorbic acid binding	Molecular function	-
PPM1G	5496	protein phosphatase, Mg2+/Mn2+ dependent, 1G	protein dephosphorylation	Biological process	9276438
PIK3R3	8503	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)	1-phosphatidylinositol-3-kinase regulator activity	Molecular function	-
PLA2G5	5322	phospholipase A2, group V	positive regulation of phospholipase activity	Biological process	22837859
SSR1	6745	signal sequence receptor, alpha	endoplasmic reticulum	Cellular component	-
ITGAV	3685	integrin, alpha V	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	Biological process	-
IFT88	8100	intraflagellar transport 88	cardiac septum morphogenesis	Biological process	-
TNK1	8711	tyrosine kinase, non-receptor, 1	signal transducer activity	Molecular function	8632913
LAP3	51056	leucine aminopeptidase 3	cytoplasm	Cellular component	-
PKN1	5585	protein kinase N1	protein serine/threonine kinase activity	Molecular function	-
DAZL	1618	deleted in azoospermia-like	spermatogenesis	Biological process	-
DDB2	1643	damage-specific DNA binding protein 2, 48kDa	nucleotide-excision repair	Biological process	-
LTA	4049	lymphotoxin alpha	membrane	Cellular component	-
BCL2L10	10017	BCL2-like 10 (apoptosis facilitator)	integral component of membrane	Cellular component	-
CCNF	899	cyclin F	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	Biological process	20596027
RAB23	51715	RAB23, member RAS oncogene family	extracellular exosome	Cellular component	23376485
KDR	3791	kinase insert domain receptor	early endosome	Cellular component	-
APOM	55937	apolipoprotein M	phototransduction, visible light	Biological process	-
CDKN1A	1026	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	regulation of protein import into nucleus, translocation	Biological process	-
CTSC	1075	cathepsin C	protein binding	Molecular function	18256700
FOXO3	2309	forkhead box O3	positive regulation of neuron apoptotic process	Biological process	10102273
HIGD1A	25994	HIG1 hypoxia inducible domain family, member 1A	mitochondrial inner membrane	Cellular component	-
CDH10	1008	cadherin 10, type 2 (T2-cadherin)	calcium ion binding	Molecular function	-
HGF	3082	hepatocyte growth factor (hepapoietin A; scatter factor)	hyaluronan metabolic process	Biological process	-
SRP9	6726	signal recognition particle 9kDa	SRP-dependent cotranslational protein targeting to membrane	Biological process	-
STEAP1B	256227	STEAP family member 1B	ferric iron import into cell	Biological process	-
PRKCG	5582	protein kinase C, gamma	protein kinase C activity	Molecular function	3755548
BMP2	650	bone morphogenetic protein 2	positive regulation of phosphatase activity	Biological process	9213002
PPP1R9B	84687	protein phosphatase 1, regulatory subunit 9B	regulation of opioid receptor signaling pathway	Biological process	-
TP53	7157	tumor protein p53	DNA strand renaturation	Biological process	8183576
IGHMBP2	3508	immunoglobulin mu binding protein 2	regulation of transcription, DNA-templated	Biological process	-
RGMA	56963	repulsive guidance molecule family member a	transferrin receptor binding	Molecular function	22728873
MAGI1	9223	membrane associated guanylate kinase, WW and PDZ domain containing 1	plasma membrane	Cellular component	-
DPYSL3	1809	dihydropyrimidinase-like 3	growth cone	Cellular component	-
SNCA	6622	synuclein, alpha (non A4 component of amyloid precursor)	mitochondrial membrane organization	Biological process	-
ULBP1	80329	UL16 binding protein 1	anchored component of plasma membrane	Cellular component	11239445
LGALS7B	653499	lectin, galactoside-binding, soluble, 7B	apoptotic process	Biological process	-
AZU1	566	azurocidin 1	extracellular region	Cellular component	11861296
TRO	7216	trophinin	negative regulation of cell growth	Biological process	-
ZAP70	7535	zeta-chain (TCR) associated protein kinase 70kDa	positive regulation of alpha-beta T cell proliferation	Biological process	-
GLI3	2737	GLI family zinc finger 3	T cell differentiation in thymus	Biological process	-
SRP9	6726	signal recognition particle 9kDa	cellular protein metabolic process	Biological process	-
PCBP2	5094	poly(rC) binding protein 2	innate immune response	Biological process	-
PDE6A	5145	phosphodiesterase 6A, cGMP-specific, rod, alpha	regulation of rhodopsin mediated signaling pathway	Biological process	-
AVP	551	arginine vasopressin	social behavior	Biological process	-
F2R	2149	coagulation factor II (thrombin) receptor	extracellular region	Cellular component	-
YTHDC1	91746	YTH domain containing 1	N6-methyladenosine-containing RNA binding	Molecular function	25242552
SRF	6722	serum response factor (c-fos serum response element-binding transcription factor)	angiogenesis involved in wound healing	Biological process	15180964
PNPLA8	50640	patatin-like phospholipase domain containing 8	small molecule metabolic process	Biological process	-
HTT	3064	huntingtin	neuron apoptotic process	Biological process	-
GSN	2934	gelsolin	sequestering of actin monomers	Biological process	19666531
SRSF9	8683	serine/arginine-rich splicing factor 9	mRNA export from nucleus	Biological process	-
LRG1	116844	leucine-rich alpha-2-glycoprotein 1	positive regulation of endothelial cell proliferation	Biological process	-
SP3	6670	Sp3 transcription factor	liver development	Biological process	-
C1orf56	54964	chromosome 1 open reading frame 56	nucleoplasm	Cellular component	-
NTRK2	4915	neurotrophic tyrosine kinase, receptor, type 2	long-term memory	Biological process	-
TRIB3	57761	tribbles pseudokinase 3	kinase activity	Molecular function	12743605
PLA2G2A	5320	phospholipase A2, group IIA (platelets, synovial fluid)	extracellular region	Cellular component	-
PBLD	64081	phenazine biosynthesis-like protein domain containing	negative regulation of epithelial to mesenchymal transition	Biological process	23687415
CHI3L1	1116	chitinase 3-like 1 (cartilage glycoprotein-39)	extracellular space	Cellular component	16502470
FOLR3	2352	folate receptor 3 (gamma)	extrinsic component of membrane	Cellular component	8110752
MSS51	118490	MSS51 mitochondrial translational activator	social behavior	Biological process	21531385
PDP2	57546	pyruvate dehyrogenase phosphatase catalytic subunit 2	[pyruvate dehydrogenase (lipoamide)] phosphatase activity	Molecular function	-
NEDD8	4738	neural precursor cell expressed, developmentally down-regulated 8	ubiquitin protein ligase binding	Molecular function	15694336
ATG4C	84938	autophagy related 4C, cysteine peptidase	C-terminal protein lipidation	Biological process	-
MAOA	4128	monoamine oxidase A	mitochondrion	Cellular component	20833797
MPPE1	65258	metallophosphoesterase 1	nucleoplasm	Cellular component	-
ZNF622	90441	zinc finger protein 622	zinc ion binding	Molecular function	-
MYLK2	85366	myosin light chain kinase 2	cardiac muscle tissue morphogenesis	Biological process	16448786
JAGN1	84522	jagunal homolog 1 (Drosophila)	granulocyte colony-stimulating factor signaling pathway	Biological process	25129144
CDC23	8697	cell division cycle 23	ubiquitin-protein transferase activity	Molecular function	12629511
WFS1	7466	Wolfram syndrome 1 (wolframin)	polyubiquitinated misfolded protein transport	Biological process	-
SLC25A24	29957	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24	integral component of membrane	Cellular component	24332718
RPGRIP1L	23322	RPGRIP1-like	negative regulation of G-protein coupled receptor protein signaling pathway	Biological process	19464661
CNDP1	84735	carnosine dipeptidase 1 (metallopeptidase M20 family)	proteolysis	Biological process	-
COL14A1	7373	collagen, type XIV, alpha 1	endoplasmic reticulum lumen	Cellular component	-
INVS	27130	inversin	ciliary base	Cellular component	-
EGFL7	51162	EGF-like-domain, multiple 7	vasculogenesis	Biological process	-
NR2F2	7026	nuclear receptor subfamily 2, group F, member 2	retinoic acid binding	Molecular function	18798693
SGMS2	166929	sphingomyelin synthase 2	integral component of cell outer membrane	Cellular component	-
PVALB	5816	parvalbumin	cytosol	Cellular component	-
HIST2H4B	554313	histone cluster 2, H4b	DNA methylation on cytosine	Biological process	-
IRF3	3661	interferon regulatory factor 3	type I interferon biosynthetic process	Biological process	-
SLC39A3	29985	solute carrier family 39 (zinc transporter), member 3	zinc ion transmembrane transporter activity	Molecular function	-
MSRB3	253827	methionine sulfoxide reductase B3	peptide-methionine (R)-S-oxide reductase activity	Molecular function	14699060
SLC4A7	9497	solute carrier family 4, sodium bicarbonate cotransporter, member 7	sodium:bicarbonate symporter activity	Molecular function	10347222
IFNG	3458	interferon, gamma	protein import into nucleus, translocation	Biological process	15604419
PTPN6	5777	protein tyrosine phosphatase, non-receptor type 6	SH2 domain binding	Molecular function	-
KRAS	3845	Kirsten rat sarcoma viral oncogene homolog	membrane raft	Cellular component	-
YBX3	8531	Y box binding protein 3	negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress	Biological process	22711822
PRKAG2	51422	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	regulation of fatty acid oxidation	Biological process	9208914
MAEA	10296	macrophage erythroblast attacher	enucleate erythrocyte development	Biological process	-
NEK3	4752	NIMA-related kinase 3	axon	Cellular component	-
NEFH	4744	neurofilament, heavy polypeptide	protein binding, bridging	Molecular function	-
MAPK1	5594	mitogen-activated protein kinase 1	late endosome	Cellular component	19565474
RBPJ	3516	recombination signal binding protein for immunoglobulin kappa J region	protein binding	Molecular function	10713164
PLK4	10733	polo-like kinase 4	cleavage furrow	Cellular component	-
JUNB	3726	jun B proto-oncogene	regulation of cell death	Biological process	-
RELA	5970	v-rel avian reticuloendotheliosis viral oncogene homolog A	toll-like receptor 3 signaling pathway	Biological process	-
CLU	1191	clusterin	extracellular matrix	Cellular component	20551380
EIF4G2	1982	eukaryotic translation initiation factor 4 gamma, 2	translation factor activity, RNA binding	Molecular function	16289705
ACTB	60	actin, beta	blood coagulation	Biological process	-
SNRPG	6637	small nuclear ribonucleoprotein polypeptide G	RNA splicing	Biological process	7744013
TTYH1	57348	tweety family member 1	regulation of anion transport	Biological process	16219661
SNAP23	8773	synaptosomal-associated protein, 23kDa	SNAP receptor activity	Molecular function	-
STC1	6781	stanniocalcin 1	regulation of anion transport	Biological process	16377640
EBF1	1879	early B-cell factor 1	DNA binding	Molecular function	-
PSIP1	11168	PC4 and SFRS1 interacting protein 1	nucleolus	Cellular component	11512661
CYP3A7	1551	cytochrome P450, family 3, subfamily A, polypeptide 7	oxygen binding	Molecular function	2722762
CNOT3	4849	CCR4-NOT transcription complex, subunit 3	transcription, DNA-templated	Biological process	-
SVIP	258010	small VCP/p97-interacting protein	smooth endoplasmic reticulum membrane	Cellular component	-
LRPPRC	10128	leucine-rich pentatricopeptide repeat containing	mitochondrion transport along microtubule	Biological process	12762840
ZNF331	55422	zinc finger protein 331	zinc ion binding	Molecular function	10502321
UFD1L	7353	ubiquitin fusion degradation 1 like (yeast)	error-free translesion synthesis	Biological process	-
APOB	338	apolipoprotein B	extracellular region	Cellular component	-
CD14	929	CD14 molecule	I-kappaB kinase/NF-kappaB signaling	Biological process	-
SKIL	6498	SKI-like proto-oncogene	response to growth factor	Biological process	19383336
ASS1	445	argininosuccinate synthase 1	diaphragm development	Biological process	-
CUL5	8065	cullin 5	G1/S transition of mitotic cell cycle	Biological process	8681378
IL18R1	8809	interleukin 18 receptor 1	positive regulation of interferon-gamma production	Biological process	-
MAP3K12	7786	mitogen-activated protein kinase kinase kinase 12	cytosol	Cellular component	-
CXCR4	7852	chemokine (C-X-C motif) receptor 4	brain development	Biological process	-
SOX9	6662	SRY (sex determining region Y)-box 9	positive regulation of mesenchymal cell proliferation	Biological process	-
RPS27	6232	ribosomal protein S27	structural constituent of ribosome	Molecular function	-
PKD1	5310	polycystic kidney disease 1 (autosomal dominant)	ion channel binding	Molecular function	9192675
HES5	388585	hes family bHLH transcription factor 5	positive regulation of transcription from RNA polymerase II promoter	Biological process	-
LTC4S	4056	leukotriene C4 synthase	enzyme activator activity	Molecular function	-
CLCN5	1184	chloride channel, voltage-sensitive 5	membrane	Cellular component	14675051
SIRT2	22933	sirtuin 2	beta-tubulin binding	Molecular function	-
ADRA1A	148	adrenoceptor alpha 1A	positive regulation of action potential	Biological process	-
C4BPB	725	complement component 4 binding protein, beta	positive regulation of protein catabolic process	Biological process	22333221
COMMD6	170622	COMM domain containing 6	protein binding	Molecular function	15799966
GINM1	116254	glycoprotein integral membrane 1	extracellular exosome	Cellular component	23376485
RANBP1	5902	RAN binding protein 1	regulation of catalytic activity	Biological process	7616957
DLG1	1739	discs, large homolog 1 (Drosophila)	positive regulation of establishment of protein localization to plasma membrane	Biological process	12970345
GPR37	2861	G protein-coupled receptor 37 (endothelin receptor type B-like)	G-protein coupled peptide receptor activity	Molecular function	23690594
ATP6V1F	9296	ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F	proton-transporting ATPase activity, rotational mechanism	Molecular function	-
EHD4	30844	EH-domain containing 4	plasma membrane	Cellular component	-
UBE2I	7329	ubiquitin-conjugating enzyme E2I	ligase activity	Molecular function	-
TREX1	11277	three prime repair exonuclease 1	3'-5' exonuclease activity	Molecular function	11278605
TAF7	6879	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa	negative regulation of protein kinase activity	Biological process	18391197
RAB21	23011	RAB21, member RAS oncogene family	cytoplasmic side of plasma membrane	Cellular component	15561770
SPATC1L	84221	spermatogenesis and centriole associated 1-like	protein binding	Molecular function	25416956
MYL4	4635	myosin, light chain 4, alkali; atrial, embryonic	regulation of the force of heart contraction	Biological process	16675844
GAS6	2621	growth arrest-specific 6	cellular response to drug	Biological process	16359517
RAD54L2	23132	RAD54-like 2 (S. cerevisiae)	DNA binding	Molecular function	-
NLRP5	126206	NLR family, pyrin domain containing 5	in utero embryonic development	Biological process	-
ATRN	8455	attractin	regulation of multicellular organism growth	Biological process	-
IL6	3569	interleukin 6	growth factor activity	Molecular function	12643274
UPF1	5976	UPF1 regulator of nonsense transcripts homolog (yeast)	exon-exon junction complex	Cellular component	16601204
IL1B	3553	interleukin 1, beta	negative regulation of MAP kinase activity	Biological process	16865359
ZIC2	7546	Zic family member 2	neural tube closure	Biological process	-
COMMD1	150684	copper metabolism (Murr1) domain containing 1	cytoplasm	Cellular component	-
OR1D4	653166	olfactory receptor, family 1, subfamily D, member 4 (gene/pseudogene)	G-protein coupled receptor activity	Molecular function	-
PSMA8	143471	proteasome (prosome, macropain) subunit, alpha type, 8	cellular nitrogen compound metabolic process	Biological process	-
PIK3CG	5294	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	endocytosis	Biological process	-
WHSC1L1	54904	Wolf-Hirschhorn syndrome candidate 1-like 1	zinc ion binding	Molecular function	-
DUOX2	50506	dual oxidase 2	response to cAMP	Biological process	-
SHBG	6462	sex hormone-binding globulin	primary spermatocyte growth	Biological process	-
GPC1	2817	glypican 1	heparan sulfate proteoglycan catabolic process	Biological process	12732622
MOGAT2	80168	monoacylglycerol O-acyltransferase 2	endoplasmic reticulum	Cellular component	14966132
ITGB1	3688	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	protease binding	Molecular function	10455171
GRHL3	57822	grainyhead-like 3 (Drosophila)	planar cell polarity pathway involved in neural tube closure	Biological process	-
APOC3	345	apolipoprotein C-III	intermediate-density lipoprotein particle	Cellular component	17336988
NANOGP1	404635	Nanog homeobox pseudogene 1	regulation of transcription, DNA-templated	Biological process	-
ATM	472	ATM serine/threonine kinase	DNA binding	Molecular function	-
CDH2	1000	cadherin 2, type 1, N-cadherin (neuronal)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	Biological process	-
COL16A1	1307	collagen, type XVI, alpha 1	protein binding	Molecular function	15165854
CSK	1445	c-src tyrosine kinase	cytosol	Cellular component	-
PSMA3	5684	proteasome (prosome, macropain) subunit, alpha type, 3	extracellular exosome	Cellular component	19056867
PHF11	51131	PHD finger protein 11	regulation of transcription, DNA-templated	Biological process	-
AKT1	207	v-akt murine thymoma viral oncogene homolog 1	cellular response to granulocyte macrophage colony-stimulating factor stimulus	Biological process	-
SET	6418	SET nuclear proto-oncogene	nucleoplasm	Cellular component	-
P2RX4	5025	purinergic receptor P2X, ligand gated ion channel, 4	protein binding	Molecular function	25416956
SLC6A1	6529	solute carrier family 6 (neurotransmitter transporter), member 1	learning	Biological process	-
F2R	2149	coagulation factor II (thrombin) receptor	positive regulation of phosphatidylinositol 3-kinase signaling	Biological process	-
DDC	1644	dopa decarboxylase (aromatic L-amino acid decarboxylase)	cellular amino acid metabolic process	Biological process	-
MLKL	197259	mixed lineage kinase domain-like	protein kinase activity	Molecular function	-
ZNRF2	223082	zinc and ring finger 2, E3 ubiquitin protein ligase	cytoplasmic vesicle membrane	Cellular component	22797923
SLC31A2	1318	solute carrier family 31 (copper transporter), member 2	cellular copper ion homeostasis	Biological process	-
FUT5	2527	fucosyltransferase 5 (alpha (1,3) fucosyltransferase)	integral component of membrane	Cellular component	-
LUZP4	51213	leucine zipper protein 4	cytoplasm	Cellular component	25662211
NOD2	64127	nucleotide-binding oligomerization domain containing 2	detection of biotic stimulus	Biological process	15967716
BAX	581	BCL2-associated X protein	positive regulation of developmental pigmentation	Biological process	-
AQP9	366	aquaporin 9	amine transmembrane transporter activity	Molecular function	9733774
OR4D2	124538	olfactory receptor, family 4, subfamily D, member 2	G-protein coupled receptor activity	Molecular function	-
ID2	3398	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	positive regulation of cell cycle arrest	Biological process	-
BRS3	680	bombesin-like receptor 3	plasma membrane	Cellular component	-
GGT5	2687	gamma-glutamyltransferase 5	leukotriene biosynthetic process	Biological process	-
TPP1	1200	tripeptidyl peptidase I	protein catabolic process	Biological process	10740217
ERLIN2	11160	ER lipid raft associated 2	extracellular exosome	Cellular component	23376485
FEZF1	389549	FEZ family zinc finger 1	nucleus	Cellular component	-
ANXA2	302	annexin A2	membrane raft assembly	Biological process	23861394
SATB2	23314	SATB homeobox 2	nuclear matrix	Cellular component	-
TTC3	7267	tetratricopeptide repeat domain 3	protein binding	Molecular function	20059950
THOC5	8563	THO complex 5	nucleus	Cellular component	19059247
VAX2	25806	ventral anterior homeobox 2	visual perception	Biological process	10485894
SLC39A14	23516	solute carrier family 39 (zinc transporter), member 14	integral component of plasma membrane	Cellular component	15642354
ZNF213	7760	zinc finger protein 213	transcription, DNA-templated	Biological process	-
CLTC	1213	clathrin, heavy chain (Hc)	clathrin light chain binding	Molecular function	4066749
FOXO1	2308	forkhead box O1	chromatin binding	Molecular function	22510882
ORAI1	84876	ORAI calcium release-activated calcium modulator 1	immune system process	Biological process	-
PSME3	10197	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	Biological process	-
DUSP3	1845	dual specificity phosphatase 3	toll-like receptor signaling pathway	Biological process	-
MEF2C	4208	myocyte enhancer factor 2C	regulation of synaptic activity	Biological process	-
PACSIN3	29763	protein kinase C and casein kinase substrate in neurons 3	membrane-bounded vesicle	Cellular component	-
ACVRL1	94	activin A receptor type II-like 1	in utero embryonic development	Biological process	-
SARM1	23098	sterile alpha and TIR motif containing 1	axon	Cellular component	-
FOXO6	100132074	forkhead box O6	sequence-specific DNA binding	Molecular function	-
ARL13B	200894	ADP-ribosylation factor-like 13B	protein binding	Molecular function	20643351
NRXN1	9378	neurexin 1	guanylate kinase-associated protein clustering	Biological process	-
NAP1L4	4676	nucleosome assembly protein 1-like 4	protein binding	Molecular function	22190034
OR10A2	341276	olfactory receptor, family 10, subfamily A, member 2	olfactory receptor activity	Molecular function	-
TAF3	83860	TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa	protein binding	Molecular function	11438666
PLXNB1	5364	plexin B1	regulation of cytoskeleton organization	Biological process	19843518
PTCH2	8643	patched 2	skin development	Biological process	-
TAP1	6890	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	antigen processing and presentation of exogenous peptide antigen via MHC class I	Biological process	-
SRRM1	10250	serine/arginine repetitive matrix 1	nuclear speck	Cellular component	-
USP17L17	100287327	ubiquitin specific peptidase 17-like family member 17	proteasome-mediated ubiquitin-dependent protein catabolic process	Biological process	-
PPID	5481	peptidylprolyl isomerase D	protein transport	Biological process	-
TLR4	7099	toll-like receptor 4	defense response to Gram-negative bacterium	Biological process	16514062
RQCD1	9125	RCD1 required for cell differentiation1 homolog (S. pombe)	negative regulation of intracellular estrogen receptor signaling pathway	Biological process	16778766
RUFY4	285180	RUN and FYVE domain containing 4	protein binding	Molecular function	25416956
BLOC1S4	55330	biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino	cytoplasm	Cellular component	-
ATR	545	ATR serine/threonine kinase	chromosome	Cellular component	-
CPB1	1360	carboxypeptidase B1 (tissue)	carboxypeptidase activity	Molecular function	1370825
DMTN	2039	dematin actin binding protein	actin filament bundle assembly	Biological process	7615546
TMEM132C	92293	transmembrane protein 132C	cellular_component	Cellular component	-
PLXNC1	10154	plexin C1	cell adhesion	Biological process	9586637
JMJD6	23210	jumonji domain containing 6	RNA binding	Molecular function	21060799
FRS2	10818	fibroblast growth factor receptor substrate 2	plasma membrane	Cellular component	-
CNTROB	116840	centrobin, centrosomal BRCA2 interacting protein	protein domain specific binding	Molecular function	11984006
GSTP1	2950	glutathione S-transferase pi 1	xenobiotic metabolic process	Biological process	-
GAB1	2549	GRB2-associated binding protein 1	regulation of cell migration	Biological process	-
RPL37A	6168	ribosomal protein L37a	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Biological process	-
TNNT2	7139	troponin T type 2 (cardiac)	troponin complex	Cellular component	12093807
CDKN1B	1027	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	negative regulation of phosphorylation	Biological process	10208428
G6PC2	57818	glucose-6-phosphatase, catalytic, 2	glucose-6-phosphatase activity	Molecular function	-
PDCD5	9141	programmed cell death 5	positive regulation of protein import into mitochondrial outer membrane	Biological process	16374546
ADGRG4	139378	adhesion G protein-coupled receptor G4	plasma membrane	Cellular component	-
TNS4	84951	tensin 4	protein binding	Molecular function	17190795
SLC11A2	4891	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2	late endosome	Cellular component	12475959
ABCD4	5826	ATP-binding cassette, sub-family D (ALD), member 4	vitamin metabolic process	Biological process	-
OR56B1	387748	olfactory receptor, family 56, subfamily B, member 1	G-protein coupled receptor activity	Molecular function	-
PPM1J	333926	protein phosphatase, Mg2+/Mn2+ dependent, 1J	protein serine/threonine phosphatase activity	Molecular function	-
BRD4	23476	bromodomain containing 4	DNA binding	Molecular function	-
MATN3	4148	matrilin 3	proteinaceous extracellular matrix	Cellular component	-
IDUA	3425	iduronidase, alpha-L-	extracellular exosome	Cellular component	23376485
VPS37A	137492	vacuolar protein sorting 37 homolog A (S. cerevisiae)	intracellular transport of virus	Biological process	-
RAB8A	4218	RAB8A, member RAS oncogene family	protein localization to plasma membrane	Biological process	-
SLC38A1	81539	solute carrier family 38, member 1	protein binding	Molecular function	25416956
PRB4	5545	proline-rich protein BstNI subfamily 4	biological_process	Biological process	-
CDH26	60437	cadherin 26	calcium ion binding	Molecular function	-
MAP2K7	5609	mitogen-activated protein kinase kinase 7	protein tyrosine kinase activity	Molecular function	-
LSM11	134353	LSM11, U7 small nuclear RNA associated	histone mRNA metabolic process	Biological process	-
DAG1	1605	dystroglycan 1 (dystrophin-associated glycoprotein 1)	myelination in peripheral nervous system	Biological process	-
BAG4	9530	BCL2-associated athanogene 4	nucleus	Cellular component	21712384
POU3F3	5455	POU class 3 homeobox 3	negative regulation of transcription, DNA-templated	Biological process	-
PKHD1	5314	polycystic kidney and hepatic disease 1 (autosomal recessive)	mitotic spindle	Cellular component	20554582
TRIM33	51592	tripartite motif containing 33	transcription initiation from RNA polymerase II promoter	Biological process	-
APOA5	116519	apolipoprotein A-V	high-density lipoprotein particle assembly	Biological process	-
DSCAML1	57453	Down syndrome cell adhesion molecule like 1	central nervous system development	Biological process	12051741
RASGRP1	10125	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	inflammatory response to antigenic stimulus	Biological process	-
MMP14	4323	matrix metallopeptidase 14 (membrane-inserted)	male gonad development	Biological process	-
SDF2	6388	stromal cell-derived factor 2	protein glycosylation	Biological process	8918255
CLIC4	25932	chloride intracellular channel 4	plasma membrane	Cellular component	19776349
TIMM13	26517	translocase of inner mitochondrial membrane 13 homolog (yeast)	mitochondrion	Cellular component	-
MAP1LC3A	84557	microtubule-associated protein 1 light chain 3 alpha	organelle membrane	Cellular component	12740394
OGT	8473	O-linked N-acetylglucosamine (GlcNAc) transferase	mitochondrion	Cellular component	-
PHB	5245	prohibitin	positive regulation of ERK1 and ERK2 cascade	Biological process	22417827
SLC17A3	10786	solute carrier family 17 (organic anion transporter), member 3	ion transmembrane transport	Biological process	-
USP54	159195	ubiquitin specific peptidase 54	ubiquitinyl hydrolase activity	Molecular function	-
AKR1C4	1109	aldo-keto reductase family 1, member C4	bile acid metabolic process	Biological process	-
TANK	10010	TRAF family member-associated NFKB activator	I-kappaB kinase/NF-kappaB signaling	Biological process	-
C8orf44-SGK3	100533105	C8orf44-SGK3 readthrough	regulation of cell migration	Biological process	20919962
ESR1	2099	estrogen receptor 1	membrane	Cellular component	11960618
TGFB1	7040	transforming growth factor, beta 1	regulation of apoptotic process	Biological process	-
MED12	9968	mediator complex subunit 12	transcription initiation from RNA polymerase II promoter	Biological process	-
CDC42	998	cell division cycle 42	regulation of protein catabolic process	Biological process	-
STX3	6809	syntaxin 3	growth cone	Cellular component	-
TRIL	9865	TLR4 interactor with leucine-rich repeats	inflammatory response	Biological process	-
AMPD1	270	adenosine monophosphate deaminase 1	myosin heavy chain binding	Molecular function	-
GBP3	2635	guanylate binding protein 3	protein binding	Molecular function	12387898
FKBP6	8468	FK506 binding protein 6, 36kDa	cytosol	Cellular component	-
TXNDC2	84203	thioredoxin domain containing 2 (spermatozoa)	nucleoplasm	Cellular component	-
KCNAB2	8514	potassium channel, voltage gated subfamily A regulatory beta subunit 2	juxtaparanode region of axon	Cellular component	-
MCFD2	90411	multiple coagulation factor deficiency 2	vesicle-mediated transport	Biological process	-
CTC1	80169	CTS telomere maintenance complex component 1	protein binding	Molecular function	19854130
IGHV3-23	28442	immunoglobulin heavy variable 3-23	extracellular exosome	Cellular component	23376485
NMT1	4836	N-myristoyltransferase 1	N-terminal peptidyl-glycine N-myristoylation	Biological process	25255805
GDF2	2658	growth differentiation factor 2	positive regulation of endothelial cell proliferation	Biological process	20406889
OR4C3	256144	olfactory receptor, family 4, subfamily C, member 3	integral component of membrane	Cellular component	-
LIG3	3980	ligase III, DNA, ATP-dependent	nucleoplasm	Cellular component	-
IL17A	3605	interleukin 17A	cell-cell signaling	Biological process	7499828
TUBB2A	7280	tubulin, beta 2A class IIa	GTP binding	Molecular function	-
DDX31	64794	DEAD (Asp-Glu-Ala-Asp) box polypeptide 31	ATP binding	Molecular function	-
IFNGR1	3459	interferon gamma receptor 1	signal transduction	Biological process	2971451
TBC1D3C	414060	TBC1 domain family, member 3C	positive regulation of GTPase activity	Biological process	-
DCTPP1	79077	dCTP pyrophosphatase 1	identical protein binding	Molecular function	16169070
TFB2M	64216	transcription factor B2, mitochondrial	rRNA (adenine-N6,N6-)-dimethyltransferase activity	Molecular function	-
LDB1	8861	LIM domain binding 1	negative regulation of erythrocyte differentiation	Biological process	-
CDH22	64405	cadherin 22, type 2	plasma membrane	Cellular component	-
FCER1G	2207	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	positive regulation of mast cell degranulation	Biological process	-
PPT1	5538	palmitoyl-protein thioesterase 1	palmitoyl-CoA hydrolase activity	Molecular function	-
AKAP5	9495	A kinase (PRKA) anchor protein 5	small molecule metabolic process	Biological process	-
CAMK2N1	55450	calcium/calmodulin-dependent protein kinase II inhibitor 1	protein kinase binding	Molecular function	-
TGFBR3	7049	transforming growth factor, beta receptor III	definitive erythrocyte differentiation	Biological process	-
TUBA3E	112714	tubulin, alpha 3e	structural constituent of cytoskeleton	Molecular function	-
UBB	7314	ubiquitin B	plasma membrane	Cellular component	-
ASB17	127247	ankyrin repeat and SOCS box containing 17	intracellular	Cellular component	-
PRMT8	56341	protein arginine methyltransferase 8	identical protein binding	Molecular function	16189514
CLSTN2	64084	calsyntenin 2	Golgi membrane	Cellular component	-
KIT	3815	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	Fc-epsilon receptor signaling pathway	Biological process	-
CYP3A4	1576	cytochrome P450, family 3, subfamily A, polypeptide 4	endoplasmic reticulum membrane	Cellular component	-
PWP1	11137	PWP1 homolog (S. cerevisiae)	transcription, DNA-templated	Biological process	7828893
GZMH	2999	granzyme H (cathepsin G-like 2, protein h-CCPX)	apoptotic process	Biological process	2193684
PLD6	201164	phospholipase D family, member 6	P granule organization	Biological process	-
ENG	2022	endoglin	protein homodimerization activity	Molecular function	8370410
CLCA4	22802	chloride channel accessory 4	proteolysis	Biological process	-
SUV39H2	79723	suppressor of variegation 3-9 homolog 2 (Drosophila)	histone methyltransferase activity (H3-K9 specific)	Molecular function	10949293
OR7A5	26659	olfactory receptor, family 7, subfamily A, member 5	plasma membrane	Cellular component	-
ST3GAL2	6483	ST3 beta-galactoside alpha-2,3-sialyltransferase 2	Golgi cisterna membrane	Cellular component	-
TNFSF13B	10673	tumor necrosis factor (ligand) superfamily, member 13b	immune response	Biological process	-
RPL7	6129	ribosomal protein L7	membrane	Cellular component	19946888
FGFR1	2260	fibroblast growth factor receptor 1	neuron migration	Biological process	15863030
PGAP3	93210	post-GPI attachment to proteins 3	hydrolase activity, acting on ester bonds	Molecular function	17021251
MC5R	4161	melanocortin 5 receptor	positive regulation of cAMP biosynthetic process	Biological process	19329486
PARP10	84875	poly (ADP-ribose) polymerase family, member 10	K63-linked polyubiquitin binding	Molecular function	23575687
YBX2	51087	Y box binding protein 2	negative regulation of translation	Biological process	-
ALOX12	239	arachidonate 12-lipoxygenase	cellular response to lipid	Biological process	-
EFNA1	1942	ephrin-A1	cell-cell signaling	Biological process	8660976
C5orf60	285679	chromosome 5 open reading frame 60	protein binding	Molecular function	25416956
RDH10	157506	retinol dehydrogenase 10 (all-trans)	oxidation-reduction process	Biological process	-
TRIM25	7706	tripartite motif containing 25	protein binding	Molecular function	19454348
DIRAS1	148252	DIRAS family, GTP-binding RAS-like 1	plasma membrane	Cellular component	12194967
ATP2A3	489	ATPase, Ca++ transporting, ubiquitous	sarcoplasmic reticulum membrane	Cellular component	-
CTBP1	1487	C-terminal binding protein 1	nucleoplasm	Cellular component	-
DUSP1	1843	dual specificity phosphatase 1	response to retinoic acid	Biological process	-
DUT	1854	deoxyuridine triphosphatase	protein binding	Molecular function	16189514
PLS3	5358	plastin 3	actin binding	Molecular function	-
GRN	2896	granulin	embryo implantation	Biological process	-
KLHL7	55975	kelch-like family member 7	plasma membrane	Cellular component	-
HOMER3	9454	homer scaffolding protein 3	G-protein coupled glutamate receptor signaling pathway	Biological process	9808458
COLEC12	81035	collectin sub-family member 12	innate immune response	Biological process	11564734
PTEN	5728	phosphatase and tensin homolog	central nervous system myelin maintenance	Biological process	-
IKZF4	64375	IKAROS family zinc finger 4 (Eos)	protein homodimerization activity	Molecular function	-
SMTN	6525	smoothelin	cytoplasm	Cellular component	-
ACTN3	89	actinin, alpha 3 (gene/pseudogene)	focal adhesion assembly	Biological process	16807302
CLU	1191	clusterin	central nervous system myelin maintenance	Biological process	21543606
KYNU	8942	kynureninase	'de novo' NAD biosynthetic process from tryptophan	Biological process	-
TNNI3K	51086	TNNI3 interacting kinase	metal ion binding	Molecular function	-
CAMK4	814	calcium/calmodulin-dependent protein kinase IV	activation of phospholipase C activity	Biological process	-
QSOX1	5768	quiescin Q6 sulfhydryl oxidase 1	flavin-linked sulfhydryl oxidase activity	Molecular function	17331072
FBXW4	6468	F-box and WD repeat domain containing 4	embryonic digit morphogenesis	Biological process	-
CDC73	79577	cell division cycle 73	positive regulation of Wnt signaling pathway	Biological process	16630820
CACNG1	786	calcium channel, voltage-dependent, gamma subunit 1	intracellular	Cellular component	-
RFX3	5991	regulatory factor X, 3 (influences HLA class II expression)	transcription from RNA polymerase II promoter	Biological process	8289803
THY1	7070	Thy-1 cell surface antigen	endoplasmic reticulum	Cellular component	-
CDH13	1012	cadherin 13	homophilic cell adhesion via plasma membrane adhesion molecules	Biological process	10601632
SERPINC1	462	serpin peptidase inhibitor, clade C (antithrombin), member 1	heparin binding	Molecular function	-
IZUMO1R	390243	IZUMO1 receptor, JUNO	fusion of sperm to egg plasma membrane	Biological process	-
SASH3	54440	SAM and SH3 domain containing 3	positive regulation of T cell cytokine production	Biological process	-
G6PC	2538	glucose-6-phosphatase, catalytic subunit	cholesterol homeostasis	Biological process	-
HOOK3	84376	hook microtubule-tethering protein 3	Golgi localization	Biological process	11238449
SEC31A	22872	SEC31 homolog A (S. cerevisiae)	Golgi membrane	Cellular component	-
CAMK2B	816	calcium/calmodulin-dependent protein kinase II beta	positive regulation of neuron projection development	Biological process	-
PGAM1	5223	phosphoglycerate mutase 1 (brain)	regulation of glycolytic process	Biological process	12189148
DSG1	1828	desmoglein 1	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	Biological process	1770008
STAG1	10274	stromal antigen 1	cytosol	Cellular component	-
REL	5966	v-rel avian reticuloendotheliosis viral oncogene homolog	I-kappaB/NF-kappaB complex	Cellular component	-
RAD51	5888	RAD51 recombinase	damaged DNA binding	Molecular function	-
OPRD1	4985	opioid receptor, delta 1	regulation of mitochondrial membrane potential	Biological process	24613828
TNFSF13	8741	tumor necrosis factor (ligand) superfamily, member 13	cytoplasm	Cellular component	19828625
P2RX1	5023	purinergic receptor P2X, ligand gated ion channel, 1	ion transport	Biological process	8834001
C1GALT1	56913	core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1	Golgi membrane	Cellular component	-
CCDC88A	55704	coiled-coil domain containing 88A	protein kinase B binding	Molecular function	16139227
OR8D1	283159	olfactory receptor, family 8, subfamily D, member 1	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
PDE6H	5149	phosphodiesterase 6H, cGMP-specific, cone, gamma	response to stimulus	Biological process	-
TRIM69	140691	tripartite motif containing 69	plasma membrane	Cellular component	-
PEBP1	5037	phosphatidylethanolamine binding protein 1	ATP binding	Molecular function	-
CCL19	6363	chemokine (C-C motif) ligand 19	release of sequestered calcium ion into cytosol	Biological process	14592837
NOP14	8602	NOP14 nucleolar protein	Noc4p-Nop14p complex	Cellular component	-
EXTL3	2137	exostosin-like glycosyltransferase 3	heparan sulfate proteoglycan biosynthetic process	Biological process	-
AKT2	208	v-akt murine thymoma viral oncogene homolog 2	carbohydrate transport	Biological process	-
ZFP90	146198	ZFP90 zinc finger protein	transcription, DNA-templated	Biological process	-
CHRNB1	1140	cholinergic receptor, nicotinic, beta 1 (muscle)	channel activity	Molecular function	8872460
LDHC	3948	lactate dehydrogenase C	carbohydrate metabolic process	Biological process	-
PAX6	5080	paired box 6	nucleoplasm	Cellular component	-
MEP1B	4225	meprin A, beta	digestion	Biological process	9288916
DTNBP1	84062	dystrobrevin binding protein 1	membrane organization	Biological process	-
SMAD3	4088	SMAD family member 3	osteoblast development	Biological process	-
TGFBI	7045	transforming growth factor, beta-induced, 68kDa	cell adhesion	Biological process	-
RAB34	83871	RAB34, member RAS oncogene family	ruffle membrane	Cellular component	17881736
ANTXR2	118429	anthrax toxin receptor 2	endoplasmic reticulum membrane	Cellular component	-
SNAI1	6615	snail family zinc finger 1	negative regulation of vitamin D biosynthetic process	Biological process	19502595
UBE2K	3093	ubiquitin-conjugating enzyme E2K	cytoplasm	Cellular component	-
ILKAP	80895	integrin-linked kinase-associated serine/threonine phosphatase	protein dephosphorylation	Biological process	-
SLC25A10	1468	solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10	mitochondrial transport	Biological process	-
BTK	695	Bruton agammaglobulinemia tyrosine kinase	membrane raft	Cellular component	15046600
EPO	2056	erythropoietin	signal transduction	Biological process	3838366
APLF	200558	aprataxin and PNKP like factor	metal ion binding	Molecular function	-
CNST	163882	consortin, connexin sorting protein	integral component of membrane	Cellular component	-
SEC61B	10952	Sec61 beta subunit	endoplasmic reticulum unfolded protein response	Biological process	-
ZNF669	79862	zinc finger protein 669	metal ion binding	Molecular function	-
BPIFB1	92747	BPI fold containing family B, member 1	innate immune response in mucosa	Biological process	21900486
PUS1	80324	pseudouridylate synthase 1	pseudouridylate synthase activity	Molecular function	10094309
ATP1A4	480	ATPase, Na+/K+ transporting, alpha 4 polypeptide	sodium:potassium-exchanging ATPase complex	Cellular component	7809153
TNFAIP1	7126	tumor necrosis factor, alpha-induced protein 1 (endothelial)	DNA replication	Biological process	-
PDCD1LG2	80380	programmed cell death 1 ligand 2	extracellular exosome	Cellular component	23376485
TNFAIP3	7128	tumor necrosis factor, alpha-induced protein 3	negative regulation of cyclin-dependent protein serine/threonine kinase activity	Biological process	-
PCMT1	5110	protein-L-isoaspartate (D-aspartate) O-methyltransferase	cytoplasm	Cellular component	-
TH	7054	tyrosine hydroxylase	circadian sleep/wake cycle	Biological process	-
PRKAA1	5562	protein kinase, AMP-activated, alpha 1 catalytic subunit	kinase binding	Molecular function	-
VPS41	27072	vacuolar protein sorting 41 homolog (S. cerevisiae)	late endosome	Cellular component	-
ARHGEF2	9181	Rho/Rac guanine nucleotide exchange factor (GEF) 2	cytoplasm	Cellular component	21887730
SORBS3	10174	sorbin and SH3 domain containing 3	positive regulation of cytoskeleton organization	Biological process	9885244
DRD5	1816	dopamine receptor D5	learning	Biological process	-
SRSF1	6426	serine/arginine-rich splicing factor 1	regulation of mRNA splicing, via spliceosome	Biological process	-
PTN	5764	pleiotrophin	bone mineralization	Biological process	-
NR2E1	7101	nuclear receptor subfamily 2, group E, member 1	negative regulation of neural precursor cell proliferation	Biological process	-
ATP2A1	487	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	negative regulation of endoplasmic reticulum calcium ion concentration	Biological process	11402072
GCLC	2729	glutamate-cysteine ligase, catalytic subunit	glutathione derivative biosynthetic process	Biological process	-
PTGER1	5731	prostaglandin E receptor 1 (subtype EP1), 42kDa	integral component of plasma membrane	Cellular component	8253813
DDX3X	1654	DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked	translation initiation factor binding	Molecular function	22323517
MLC1	23209	megalencephalic leukoencephalopathy with subcortical cysts 1	protein binding	Molecular function	17628813
MCM4	4173	minichromosome maintenance complex component 4	mitotic cell cycle	Biological process	-
U2AF1	7307	U2 small nuclear RNA auxiliary factor 1	nuclear speck	Cellular component	-
LRP8	7804	low density lipoprotein receptor-related protein 8, apolipoprotein e receptor	axon	Cellular component	-
DRD1	1812	dopamine receptor D1	activation of adenylate cyclase activity	Biological process	2168520
DMD	1756	dystrophin	muscle cell cellular homeostasis	Biological process	-
SEMA3A	10371	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	neuron migration	Biological process	-
UHRF1	29128	ubiquitin-like with PHD and ring finger domains 1	ubiquitin protein ligase activity	Molecular function	-
PSPN	5623	persephin	nervous system development	Biological process	9491986
RPS6KA5	9252	ribosomal protein S6 kinase, 90kDa, polypeptide 5	innate immune response	Biological process	-
TIMP1	7076	TIMP metallopeptidase inhibitor 1	extracellular region	Cellular component	-
GOT1	2805	glutamic-oxaloacetic transaminase 1, soluble	glucose metabolic process	Biological process	-
CHRNG	1146	cholinergic receptor, nicotinic, gamma (muscle)	integral component of plasma membrane	Cellular component	3967651
RAD18	56852	RAD18 E3 ubiquitin protein ligase	chromatin	Cellular component	-
HMGCL	3155	3-hydroxymethyl-3-methylglutaryl-CoA lyase	protein tetramerization	Biological process	12464283
TACR1	6869	tachykinin receptor 1	positive regulation of action potential	Biological process	-
PSMD9	5715	proteasome (prosome, macropain) 26S subunit, non-ATPase, 9	antigen processing and presentation of exogenous peptide antigen via MHC class I	Biological process	-
DGKA	1606	diacylglycerol kinase, alpha 80kDa	blood coagulation	Biological process	-
UGT1A6	54578	UDP glucuronosyltransferase 1 family, polypeptide A6	integral component of membrane	Cellular component	-
NEDD4	4734	neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase	regulation of dendrite morphogenesis	Biological process	-
MYL12A	10627	myosin, light chain 12A, regulatory, non-sarcomeric	ephrin receptor signaling pathway	Biological process	-
BABAM1	29086	BRISC and BRCA1 A complex member 1	positive regulation of DNA repair	Biological process	19261746
SMDT1	91689	single-pass membrane protein with aspartate-rich tail 1	integral component of mitochondrial inner membrane	Cellular component	24231807
ANO6	196527	anoctamin 6	calcium activated cation channel activity	Molecular function	-
CCL5	6352	chemokine (C-C motif) ligand 5	phospholipase activator activity	Molecular function	10734056
TRIM21	6737	tripartite motif containing 21	innate immune response	Biological process	-
KCNE5	23630	potassium channel, voltage gated subfamily E regulatory beta subunit 5	membrane repolarization during cardiac muscle cell action potential	Biological process	21493962
LHX1	3975	LIM homeobox 1	metanephric renal vesicle morphogenesis	Biological process	-
PKD1	5310	polycystic kidney disease 1 (autosomal dominant)	positive regulation of transcription from RNA polymerase II promoter	Biological process	16311606
PRPF19	27339	pre-mRNA processing factor 19	ligase activity	Molecular function	-
FARSB	10056	phenylalanyl-tRNA synthetase, beta subunit	gene expression	Biological process	-
UCK2	7371	uridine-cytidine kinase 2	CMP salvage	Biological process	-
PLCG1	5335	phospholipase C, gamma 1	cell-cell junction	Cellular component	-
NRG1	3084	neuregulin 1	neuromuscular junction	Cellular component	-
ST3GAL3	6487	ST3 beta-galactoside alpha-2,3-sialyltransferase 3	protein N-linked glycosylation via asparagine	Biological process	-
ATP1A1	476	ATPase, Na+/K+ transporting, alpha 1 polypeptide	regulation of blood pressure	Biological process	-
INHBA	3624	inhibin, beta A	endodermal cell differentiation	Biological process	21828274
GABRA6	2559	gamma-aminobutyric acid (GABA) A receptor, alpha 6	synaptic transmission	Biological process	-
USP33	23032	ubiquitin specific peptidase 33	regulation of proteasomal protein catabolic process	Biological process	-
CXCR3	2833	chemokine (C-X-C motif) receptor 3	cell surface receptor signaling pathway	Biological process	11554781
RBM47	54502	RNA binding motif protein 47	nucleus	Cellular component	-
TSPO	706	translocator protein (18kDa)	cellular hypotonic response	Biological process	-
KCNJ2	3759	potassium channel, inwardly rectifying subfamily J, member 2	magnesium ion transport	Biological process	-
AQP3	360	aquaporin 3 (Gill blood group)	cell-cell junction	Cellular component	18718702
PPP2R3A	5523	protein phosphatase 2, regulatory subunit B'', alpha	protein phosphatase type 2A regulator activity	Molecular function	8392071
TNFRSF13C	115650	tumor necrosis factor receptor superfamily, member 13C	positive regulation of germinal center formation	Biological process	-
NANOS3	342977	nanos homolog 3 (Drosophila)	regulation of translation	Biological process	-
BIRC5	332	baculoviral IAP repeat containing 5	spindle microtubule	Cellular component	11069302
MYSM1	114803	Myb-like, SWIRM and MPN domains 1	chromatin remodeling	Biological process	17707232
IL1RL1	9173	interleukin 1 receptor-like 1	receptor signaling protein activity	Molecular function	1482686
PVRL2	5819	poliovirus receptor-related 2 (herpesvirus entry mediator B)	protein binding	Molecular function	16189514
THOP1	7064	thimet oligopeptidase 1	protein binding	Molecular function	19614740
ANKH	56172	ANKH inorganic pyrophosphate transport regulator	phosphate ion transmembrane transporter activity	Molecular function	-
CTC1	80169	CTS telomere maintenance complex component 1	hematopoietic stem cell proliferation	Biological process	-
MRPS24	64951	mitochondrial ribosomal protein S24	mitochondrial inner membrane	Cellular component	-
TRAP1	10131	TNF receptor-associated protein 1	negative regulation of cellular respiration	Biological process	23564345
FGF7	2252	fibroblast growth factor 7	extracellular region	Cellular component	-
BACH1	571	BTB and CNC homology 1, basic leucine zipper transcription factor 1	negative regulation of transcription from RNA polymerase II promoter	Biological process	21555518
F2RL1	2150	coagulation factor II (thrombin) receptor-like 1	positive regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	11413129
EDN2	1907	endothelin 2	positive regulation of cell proliferation	Biological process	1917960
ATP8A1	10396	ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1	ATP binding	Molecular function	-
CYP2E1	1571	cytochrome P450, family 2, subfamily E, polypeptide 1	drug metabolic process	Biological process	18356043
SCRIB	23513	scribbled planar cell polarity protein	positive regulation of apoptotic process	Biological process	19041750
ROS1	6098	ROS proto-oncogene 1 , receptor tyrosine kinase	ATP binding	Molecular function	-
TBC1D7	51256	TBC1 domain family, member 7	protein binding	Molecular function	17658474
NME3	4832	NME/NM23 nucleoside diphosphate kinase 3	nucleoside diphosphate phosphorylation	Biological process	-
GCG	2641	glucagon	positive regulation of calcium ion import	Biological process	-
HAUS5	23354	HAUS augmin-like complex, subunit 5	cytoplasm	Cellular component	-
SEC23A	10484	Sec23 homolog A (S. cerevisiae)	ER to Golgi transport vesicle membrane	Cellular component	-
PI4K2A	55361	phosphatidylinositol 4-kinase type 2 alpha	BLOC-1 complex	Cellular component	21998198
PSMB11	122706	proteasome (prosome, macropain) subunit, beta type, 11	gene expression	Biological process	-
KRT9	3857	keratin 9, type I	nucleus	Cellular component	21630459
KCNIP4	80333	Kv channel interacting protein 4	regulation of potassium ion transmembrane transport	Biological process	-
SNX13	23161	sorting nexin 13	phosphatidylinositol-3-phosphate binding	Molecular function	25148684
LRRK2	120892	leucine-rich repeat kinase 2	trans-Golgi network	Cellular component	-
MLH1	4292	mutL homolog 1	nuclear-transcribed mRNA poly(A) tail shortening	Biological process	-
ALDH1B1	219	aldehyde dehydrogenase 1 family, member B1	carbohydrate metabolic process	Biological process	1306115
MDM2	4193	MDM2 proto-oncogene, E3 ubiquitin protein ligase	protein localization to nucleus	Biological process	10360174
OXTR	5021	oxytocin receptor	cytosol	Cellular component	-
SPTAN1	6709	spectrin, alpha, non-erythrocytic 1	extracellular vesicle	Cellular component	24769233
NEK2	4751	NIMA-related kinase 2	nucleus	Cellular component	-
SELP	6403	selectin P (granule membrane protein 140kDa, antigen CD62)	extracellular space	Cellular component	9290466
HMGB2	3148	high mobility group box 2	positive regulation of nuclease activity	Biological process	978439
IL23R	149233	interleukin 23 receptor	positive regulation of memory T cell differentiation	Biological process	-
ZNF737	100129842	zinc finger protein 737	nucleus	Cellular component	-
QPCTL	54814	glutaminyl-peptide cyclotransferase-like	Golgi membrane	Cellular component	-
TOR1A	1861	torsin family 1, member A (torsin A)	membrane	Cellular component	23569223
STEAP3	55240	STEAP family member 3, metalloreductase	cellular iron ion homeostasis	Biological process	-
SPIC	121599	Spi-C transcription factor (Spi-1/PU.1 related)	sequence-specific DNA binding RNA polymerase II transcription factor activity	Molecular function	-
RAB3A	5864	RAB3A, member RAS oncogene family	protein secretion	Biological process	-
PTPRM	5797	protein tyrosine phosphatase, receptor type, M	cell-cell adherens junction	Cellular component	17965016
IGFBP1	3484	insulin-like growth factor binding protein 1	cellular protein metabolic process	Biological process	-
HES3	390992	hes family bHLH transcription factor 3	trochlear nerve development	Biological process	-
RETN	56729	resistin	extracellular exosome	Cellular component	23376485
ARHGEF2	9181	Rho/Rac guanine nucleotide exchange factor (GEF) 2	zinc ion binding	Molecular function	11912491
PHTF1	10745	putative homeodomain transcription factor 1	regulation of transcription, DNA-templated	Biological process	-
ITGA2B	3674	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	axon guidance	Biological process	-
RPL10	6134	ribosomal protein L10	translational termination	Biological process	-
ABCB4	5244	ATP-binding cassette, sub-family B (MDR/TAP), member 4	small molecule metabolic process	Biological process	-
COX19	90639	COX19 cytochrome c oxidase assembly factor	cytoplasm	Cellular component	-
S100B	6285	S100 calcium binding protein B	axonogenesis	Biological process	8202493
ADA	100	adenosine deaminase	zinc ion binding	Molecular function	-
KRT76	51350	keratin 76, type II	keratin filament	Cellular component	-
SH3GL2	6456	SH3-domain GRB2-like 2	cytosol	Cellular component	-
S100A6	6277	S100 calcium binding protein A6	calcium-dependent protein binding	Molecular function	10913138
MYT1	4661	myelin transcription factor 1	nucleus	Cellular component	1280325
SEZ6	124925	seizure related 6 homolog (mouse)	synapse maturation	Biological process	-
OSTM1	28962	osteopetrosis associated transmembrane protein 1	nucleus	Cellular component	-
PMAIP1	5366	phorbol-12-myristate-13-acetate-induced protein 1	positive regulation of neuron apoptotic process	Biological process	-
AP2S1	1175	adaptor-related protein complex 2, sigma 1 subunit	plasma membrane	Cellular component	-
MMP24	10893	matrix metallopeptidase 24 (membrane-inserted)	trans-Golgi network membrane	Cellular component	-
BOLA3	388962	bolA family member 3	molecular_function	Molecular function	-
GAL	51083	galanin/GMAP prepropeptide	insulin secretion	Biological process	1370155
GRM7	2917	glutamate receptor, metabotropic 7	regulation of synaptic transmission, glutamatergic	Biological process	-
ANAPC5	51433	anaphase promoting complex subunit 5	cytosol	Cellular component	-
PAX9	5083	paired box 9	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	-
PREX2	80243	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2	G-protein coupled receptor signaling pathway	Biological process	15304343
VHL	7428	von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase	proteolysis	Biological process	10353251
HKR1	284459	HKR1, GLI-Kruppel zinc finger family member	transcription, DNA-templated	Biological process	-
GOLIM4	27333	golgi integral membrane protein 4	nucleoplasm	Cellular component	-
NRXN1	9378	neurexin 1	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity	Biological process	-
ATOX1	475	antioxidant 1 copper chaperone	response to oxidative stress	Biological process	9430722
ILF2	3608	interleukin enhancer binding factor 2	positive regulation of transcription, DNA-templated	Biological process	11739746
SEMA3F	6405	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	facial nerve structural organization	Biological process	-
THOC6	79228	THO complex 6	THO complex	Cellular component	15998806
ACSM2A	123876	acyl-CoA synthetase medium-chain family member 2A	fatty acid metabolic process	Biological process	-
CHRM2	1129	cholinergic receptor, muscarinic 2	G-protein coupled acetylcholine receptor signaling pathway	Biological process	24256733
DAZAP1	26528	DAZ associated protein 1	maternal placenta development	Biological process	-
ANP32B	10541	acidic (leucine-rich) nuclear phosphoprotein 32 family, member B	RNA polymerase binding	Molecular function	9285060
GUCA1B	2979	guanylate cyclase activator 1B (retina)	visual perception	Biological process	-
BLM	641	Bloom syndrome, RecQ helicase-like	DNA duplex unwinding	Biological process	21325134
PGAM4	441531	phosphoglycerate mutase family member 4	glycolytic process	Biological process	11961099
TRIM25	7706	tripartite motif containing 25	cytoplasm	Cellular component	-
AR	367	androgen receptor	transcription initiation from RNA polymerase II promoter	Biological process	-
ADCY6	112	adenylate cyclase 6	energy reserve metabolic process	Biological process	-
INPP5K	51763	inositol polyphosphate-5-phosphatase K	ruffle membrane	Cellular component	12556481
GNB2L1	10399	guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1	rhythmic process	Biological process	-
APLP2	334	amyloid beta (A4) precursor-like protein 2	serine-type endopeptidase inhibitor activity	Molecular function	-
CUX2	23316	cut-like homeobox 2	extracellular exosome	Cellular component	19056867
BMP7	655	bone morphogenetic protein 7	regulation of branching involved in prostate gland morphogenesis	Biological process	-
TGFB1	7040	transforming growth factor, beta 1	enzyme binding	Molecular function	19366691
ITPR3	3710	inositol 1,4,5-trisphosphate receptor, type 3	blood coagulation	Biological process	-
PSME1	5720	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)	antigen processing and presentation of peptide antigen via MHC class I	Biological process	-
PPP1R3C	5507	protein phosphatase 1, regulatory subunit 3C	protein phosphatase regulator activity	Molecular function	-
UBE2D1	7321	ubiquitin-conjugating enzyme E2D 1	ubiquitin ligase complex	Cellular component	15247280
HIST3H3	8290	histone cluster 3, H3	telomere maintenance	Biological process	-
TNIP2	79155	TNFAIP3 interacting protein 2	toll-like receptor 2 signaling pathway	Biological process	-
RGS1	5996	regulator of G-protein signaling 1	signal transduction	Biological process	8241276
MPHOSPH8	54737	M-phase phosphoprotein 8	nucleoplasm	Cellular component	-
GJD3	125111	gap junction protein, delta 3, 31.9kDa	response to glucose	Biological process	-
APOD	347	apolipoprotein D	lipid transport	Biological process	3453108
QKI	9444	QKI, KH domain containing, RNA binding	long-chain fatty acid biosynthetic process	Biological process	-
KLF11	8462	Kruppel-like factor 11	metal ion binding	Molecular function	-
RPP14	11102	ribonuclease P/MRP 14kDa subunit	nucleus	Cellular component	-
PARK7	11315	parkinson protein 7	positive regulation of transcription from RNA polymerase II promoter	Biological process	16731528
MSH2	4436	mutS homolog 2	negative regulation of neuron apoptotic process	Biological process	-
LGALS3BP	3959	lectin, galactoside-binding, soluble, 3 binding protein	extracellular exosome	Cellular component	19056867
MGA	23269	MGA, MAX dimerization protein	MLL1 complex	Cellular component	15960975
SLC35A4	113829	solute carrier family 35, member A4	Golgi membrane	Cellular component	-
CLOCK	9575	clock circadian regulator	protein binding	Molecular function	14645221
DDX4	54514	DEAD (Asp-Glu-Ala-Asp) box polypeptide 4	cytoplasm	Cellular component	21421998
ARHGAP4	393	Rho GTPase activating protein 4	focal adhesion	Cellular component	-
TMEM147	10430	transmembrane protein 147	protein destabilization	Biological process	20538592
PRDM4	11108	PR domain containing 4	nucleus	Cellular component	-
ALPL	249	alkaline phosphatase, liver/bone/kidney	endochondral ossification	Biological process	-
AMELX	265	amelogenin, X-linked	cell adhesion	Biological process	1734713
EIF4G1	1981	eukaryotic translation initiation factor 4 gamma, 1	nuclear-transcribed mRNA poly(A) tail shortening	Biological process	-
RHOA	387	ras homolog family member A	apolipoprotein A-I-mediated signaling pathway	Biological process	23726972
CCL19	6363	chemokine (C-C motif) ligand 19	response to prostaglandin E	Biological process	14592837
MYH8	4626	myosin, heavy chain 8, skeletal muscle, perinatal	actin filament binding	Molecular function	2373371
CHMP4B	128866	charged multivesicular body protein 4B	membrane coat	Cellular component	24878737
PITPNM1	9600	phosphatidylinositol transfer protein, membrane-associated 1	protein transport	Biological process	-
MICU2	221154	mitochondrial calcium uptake 2	uniplex complex	Cellular component	22925203
PSEN2	5664	presenilin 2	integral component of plasma membrane	Cellular component	15274632
MSGN1	343930	mesogenin 1	segment specification	Biological process	-
LPCAT3	10162	lysophosphatidylcholine acyltransferase 3	endoplasmic reticulum membrane	Cellular component	-
GABRA1	2554	gamma-aminobutyric acid (GABA) A receptor, alpha 1	synaptic transmission, GABAergic	Biological process	-
MAP2K1	5604	mitogen-activated protein kinase kinase 1	innate immune response	Biological process	-
BMP5	653	bone morphogenetic protein 5	SMAD protein signal transduction	Biological process	-
FZD4	8322	frizzled class receptor 4	PDZ domain binding	Molecular function	19388021
CD6	923	CD6 molecule	scavenger receptor activity	Molecular function	-
KRIT1	889	KRIT1, ankyrin repeat containing	microtubule binding	Molecular function	17916086
MICU1	10367	mitochondrial calcium uptake 1	calcium ion transmembrane import into mitochondrion	Biological process	22925203
CREBBP	1387	CREB binding protein	cellular response to hypoxia	Biological process	-
RAB11FIP2	22841	RAB11 family interacting protein 2 (class I)	transmembrane transport	Biological process	-
SYTL3	94120	synaptotagmin-like 3	intracellular protein transport	Biological process	-
ARF5	381	ADP-ribosylation factor 5	protein binding	Molecular function	17030804
CYP11B2	1585	cytochrome P450, family 11, subfamily B, polypeptide 2	mitochondrion	Cellular component	1741400
WIPI1	55062	WD repeat domain, phosphoinositide interacting 1	cellular response to nitrogen starvation	Biological process	-
HCK	3055	HCK proto-oncogene, Src family tyrosine kinase	integrin-mediated signaling pathway	Biological process	18538446
ATP7A	538	ATPase, Cu++ transporting, alpha polypeptide	pyramidal neuron development	Biological process	-
SMC1A	8243	structural maintenance of chromosomes 1A	microtubule motor activity	Molecular function	12199140
GLI3	2737	GLI family zinc finger 3	ciliary tip	Cellular component	-
KRBOX4	55634	KRAB box domain containing 4	regulation of transcription, DNA-templated	Biological process	-
PTGS2	5743	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	positive regulation of apoptotic process	Biological process	-
ACIN1	22985	apoptotic chromatin condensation inducer 1	cytoplasm	Cellular component	-
GABARAP	11337	GABA(A) receptor-associated protein	nucleophagy	Biological process	-
DNAJC13	23317	DnaJ (Hsp40) homolog, subfamily C, member 13	lysosomal membrane	Cellular component	17897319
RGL3	57139	ral guanine nucleotide dissociation stimulator-like 3	small GTPase mediated signal transduction	Biological process	-
SNRPA	6626	small nuclear ribonucleoprotein polypeptide A	poly(A) RNA binding	Molecular function	22681889
INPP5D	3635	inositol polyphosphate-5-phosphatase, 145kDa	phosphatidylinositol biosynthetic process	Biological process	-
PRPF3	9129	pre-mRNA processing factor 3	poly(A) RNA binding	Molecular function	22681889
SUSD5	26032	sushi domain containing 5	cell adhesion	Biological process	-
TRAF5	7188	TNF receptor-associated factor 5	positive regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	12761501
TRPV4	59341	transient receptor potential cation channel, subfamily V, member 4	ATP binding	Molecular function	-
ADCY7	113	adenylate cyclase 7	cellular response to glucagon stimulus	Biological process	-
NRL	4901	neural retina leucine zipper	retinal rod cell development	Biological process	-
SYTL4	94121	synaptotagmin-like 4	negative regulation of insulin secretion	Biological process	-
DHX30	22907	DEAH (Asp-Glu-Ala-His) box helicase 30	mitochondrial nucleoid	Cellular component	18063578
ITGB1	3688	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	response to activity	Biological process	-
CCL13	6357	chemokine (C-C motif) ligand 13	immune response	Biological process	-
GAB2	9846	GRB2-associated binding protein 2	positive regulation of cell proliferation	Biological process	19172738
CNOT10	25904	CCR4-NOT transcription complex, subunit 10	nuclear-transcribed mRNA poly(A) tail shortening	Biological process	-
TIMP1	7076	TIMP metallopeptidase inhibitor 1	response to peptide hormone	Biological process	-
KCNT1	57582	potassium channel, sodium activated subfamily T, member 1	calcium-activated potassium channel activity	Molecular function	-
BOK	666	BCL2-related ovarian killer	intrinsic apoptotic signaling pathway in response to DNA damage	Biological process	-
SNAI3	333929	snail family zinc finger 3	transcription factor complex	Cellular component	-
VWA1	64856	von Willebrand factor A domain containing 1	extracellular exosome	Cellular component	19199708
ASIC2	40	acid sensing (proton gated) ion channel 2	ion gated channel activity	Molecular function	-
FIGNL1	63979	fidgetin-like 1	osteoblast proliferation	Biological process	-
TMEM64	169200	transmembrane protein 64	endoplasmic reticulum	Cellular component	-
CXCL9	4283	chemokine (C-X-C motif) ligand 9	chemokine-mediated signaling pathway	Biological process	-
LYN	4067	LYN proto-oncogene, Src family tyrosine kinase	positive regulation of glial cell proliferation	Biological process	-
PDGFA	5154	platelet-derived growth factor alpha polypeptide	negative regulation of phosphatidylinositol biosynthetic process	Biological process	2538439
LAT2	7462	linker for activation of T cells family, member 2	mast cell granule	Cellular component	-
FANCG	2189	Fanconi anemia, complementation group G	Fanconi anaemia nuclear complex	Cellular component	20347428
PTGS2	5743	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	protein homodimerization activity	Molecular function	-
USP43	124739	ubiquitin specific peptidase 43	regulation of proteasomal protein catabolic process	Biological process	-
GEMIN8	54960	gem (nuclear organelle) associated protein 8	protein binding	Molecular function	17023415
ARFIP2	23647	ADP-ribosylation factor interacting protein 2	phosphatidylinositol-4-phosphate binding	Molecular function	23695357
MYH3	4621	myosin, heavy chain 3, skeletal muscle, embryonic	microfilament motor activity	Molecular function	1691980
UBE3A	7337	ubiquitin protein ligase E3A	brain development	Biological process	8988171
COPS3	8533	COP9 signalosome subunit 3	cytoplasm	Cellular component	-
THEMIS	387357	thymocyte selection associated	T cell receptor signaling pathway	Biological process	-
UTP18	51096	UTP18 small subunit (SSU) processome component homolog (yeast)	small-subunit processome	Cellular component	-
ADRBK1	156	adrenergic, beta, receptor kinase 1	cytosol	Cellular component	-
RASAL3	64926	RAS protein activator like 3	negative regulation of Ras protein signal transduction	Biological process	-
UROS	7390	uroporphyrinogen III synthase	cofactor binding	Molecular function	-
POLR3A	11128	polymerase (RNA) III (DNA directed) polypeptide A, 155kDa	transcription from RNA polymerase III promoter	Biological process	-
ARID4B	51742	AT rich interactive domain 4B (RBP1-like)	nucleoplasm	Cellular component	-
SLC5A1	6523	solute carrier family 5 (sodium/glucose cotransporter), member 1	intestinal absorption	Biological process	-
RET	5979	ret proto-oncogene	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	Biological process	21357690
RPN2	6185	ribophorin II	endoplasmic reticulum membrane	Cellular component	-
SYT4	6860	synaptotagmin IV	cell junction	Cellular component	-
TRIM22	10346	tripartite motif containing 22	response to virus	Biological process	7797467
FABP5	2171	fatty acid binding protein 5 (psoriasis-associated)	transporter activity	Molecular function	-
GATA3	2625	GATA binding protein 3	embryonic hemopoiesis	Biological process	-
NEBL	10529	nebulette	cardiac muscle thin filament assembly	Biological process	11822876
BMP4	652	bone morphogenetic protein 4	telencephalon regionalization	Biological process	-
CNTNAP1	8506	contactin associated protein 1	protein binding	Molecular function	17474147
NRP2	8828	neuropilin 2	sympathetic neuron projection guidance	Biological process	-
SSX1	6756	synovial sarcoma, X breakpoint 1	protein binding	Molecular function	25416956
CXCR4	7852	chemokine (C-X-C motif) receptor 4	cell-cell junction	Cellular component	-
SLC6A4	6532	solute carrier family 6 (neurotransmitter transporter), member 4	response to estradiol	Biological process	-
KIAA2022	340533	KIAA2022	DNA-directed DNA polymerase activity	Molecular function	-
CEL	1056	carboxyl ester lipase	lipid metabolic process	Biological process	8639615
OPRM1	4988	opioid receptor, mu 1	morphine receptor activity	Molecular function	-
SSBP1	6742	single-stranded DNA binding protein 1, mitochondrial	mitochondrial nucleoid	Cellular component	18063578
IRAK4	51135	interleukin-1 receptor-associated kinase 4	toll-like receptor 5 signaling pathway	Biological process	-
SLC5A1	6523	solute carrier family 5 (sodium/glucose cotransporter), member 1	glucose transport	Biological process	8563765
ITPR1	3708	inositol 1,4,5-trisphosphate receptor, type 1	platelet activation	Biological process	-
QDPR	5860	quinoid dihydropteridine reductase	small molecule metabolic process	Biological process	-
NAV2	89797	neuron navigator 2	interstitial matrix	Cellular component	-
TCIRG1	10312	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3	ATP hydrolysis coupled proton transport	Biological process	-
KIN	22944	Kin17 DNA and RNA binding protein	RNA binding	Molecular function	17045609
RBM5	10181	RNA binding motif protein 5	DNA binding	Molecular function	10352938
GABPA	2551	GA binding protein transcription factor, alpha subunit 60kDa	sequence-specific DNA binding transcription factor activity	Molecular function	7590737
MLH1	4292	mutL homolog 1	nucleoplasm	Cellular component	-
HOXB3	3213	homeobox B3	glossopharyngeal nerve morphogenesis	Biological process	-
CCL13	6357	chemokine (C-C motif) ligand 13	regulation of cell shape	Biological process	10072545
RPIA	22934	ribose 5-phosphate isomerase A	pentose-phosphate shunt, non-oxidative branch	Biological process	-
KRT2	3849	keratin 2, type II	intermediate filament cytoskeleton	Cellular component	-
PVR	5817	poliovirus receptor	susceptibility to natural killer cell mediated cytotoxicity	Biological process	12913096
ALOX12	239	arachidonate 12-lipoxygenase	cytoplasm	Cellular component	8319693
BMP7	655	bone morphogenetic protein 7	branching involved in salivary gland morphogenesis	Biological process	-
EPO	2056	erythropoietin	negative regulation of cation channel activity	Biological process	14569084
CTSG	1511	cathepsin G	negative regulation of growth of symbiont in host	Biological process	-
PYY	5697	peptide YY	protein binding	Molecular function	23597562
PRKG1	5592	protein kinase, cGMP-dependent, type I	cytosol	Cellular component	-
ONECUT2	9480	one cut homeobox 2	cell fate commitment	Biological process	-
CHUK	1147	conserved helix-loop-helix ubiquitous kinase	fibroblast growth factor receptor signaling pathway	Biological process	-
LRG1	116844	leucine-rich alpha-2-glycoprotein 1	transforming growth factor beta receptor binding	Molecular function	-
MAP1LC3B	81631	microtubule-associated protein 1 light chain 3 beta	mitochondrion	Cellular component	25215947
ARSB	411	arylsulfatase B	arylsulfatase activity	Molecular function	-
BUB3	9184	BUB3 mitotic checkpoint protein	attachment of spindle microtubules to kinetochore	Biological process	18199686
KPTN	11133	kaptin (actin binding protein)	stereocilium	Cellular component	-
CORO1A	11151	coronin, actin binding protein, 1A	phosphatidylinositol 3-kinase binding	Molecular function	11094157
NAA15	80155	N(alpha)-acetyltransferase 15, NatA auxiliary subunit	angiogenesis	Biological process	-
ACTL7A	10881	actin-like 7A	motile cilium	Cellular component	-
MYO9B	4650	myosin IXB	actin filament-based movement	Biological process	8907710
TMEM235	283999	transmembrane protein 235	structural molecule activity	Molecular function	-
GTF3C1	2975	general transcription factor IIIC, polypeptide 1, alpha 220kDa	nucleoplasm	Cellular component	-
TDP1	55775	tyrosyl-DNA phosphodiesterase 1	single-stranded DNA binding	Molecular function	15811850
FOXF2	2295	forkhead box F2	palate development	Biological process	19276632
STAT3	6774	signal transducer and activator of transcription 3 (acute-phase response factor)	signal transduction	Biological process	10205054
SNX27	81609	sorting nexin family member 27	cytoplasm	Cellular component	-
OR14A2	388761	olfactory receptor, family 14, subfamily A, member 2	sensory perception of smell	Biological process	-
ITPR3	3710	inositol 1,4,5-trisphosphate receptor, type 3	positive regulation of cytosolic calcium ion concentration	Biological process	-
VAV1	7409	vav 1 guanine nucleotide exchange factor	cell-cell junction	Cellular component	-
GRIK3	2899	glutamate receptor, ionotropic, kainate 3	negative regulation of synaptic transmission, glutamatergic	Biological process	-
COLEC12	81035	collectin sub-family member 12	collagen trimer	Cellular component	-
RGP1	9827	RGP1 retrograde golgi transport homolog (S. cerevisiae)	cytosol	Cellular component	23091056
ATP6V1F	9296	ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F	ATP hydrolysis coupled proton transport	Biological process	-
FKBP5	2289	FK506 binding protein 5	cytoplasm	Cellular component	-
PPP2R3A	5523	protein phosphatase 2, regulatory subunit B'', alpha	calcium ion binding	Molecular function	-
ACKR2	1238	atypical chemokine receptor 2	neutrophil activation	Biological process	-
PDE12	201626	phosphodiesterase 12	metal ion binding	Molecular function	-
C11orf54	28970	chromosome 11 open reading frame 54	hydrolase activity, acting on ester bonds	Molecular function	16522806
NR1I2	8856	nuclear receptor subfamily 1, group I, member 2	drug binding	Molecular function	12578355
TNMD	64102	tenomodulin	protein binding	Molecular function	25416956
RFK	55312	riboflavin kinase	small molecule metabolic process	Biological process	-
ABL1	25	ABL proto-oncogene 1, non-receptor tyrosine kinase	positive regulation of Wnt signaling pathway, planar cell polarity pathway	Biological process	-
LAT	27040	linker for activation of T cells	cell-cell junction	Cellular component	-
SMIM11	54065	small integral membrane protein 11	biological_process	Biological process	-
ATP6V1B1	525	ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1	protein complex binding	Molecular function	-
MSX2	4488	msh homeobox 2	negative regulation of fat cell differentiation	Biological process	-
HBA2	3040	hemoglobin, alpha 2	heme binding	Molecular function	-
MAP2K3	5606	mitogen-activated protein kinase kinase 3	toll-like receptor 4 signaling pathway	Biological process	-
PIK3CB	5291	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta	neurotrophin TRK receptor signaling pathway	Biological process	-
EP400	57634	E1A binding protein p400	NuA4 histone acetyltransferase complex	Cellular component	14966270
C2	717	complement component 2	serine-type endopeptidase activity	Molecular function	-
CRKL	1399	v-crk avian sarcoma virus CT10 oncogene homolog-like	cytosol	Cellular component	-
CHRNA3	1136	cholinergic receptor, nicotinic, alpha 3 (neuronal)	regulation of dendrite morphogenesis	Biological process	-
LGI1	9211	leucine-rich, glioma inactivated 1	receptor binding	Molecular function	20463223
PDSS1	23590	prenyl (decaprenyl) diphosphate synthase, subunit 1	small molecule metabolic process	Biological process	-
SLC5A6	8884	solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6	vitamin metabolic process	Biological process	-
TMEM165	55858	transmembrane protein 165	late endosome membrane	Cellular component	-
KMT2E	55904	lysine (K)-specific methyltransferase 2E	neutrophil mediated immunity	Biological process	-
CTAGE5	4253	CTAGE family, member 5	positive regulation of catalytic activity	Biological process	9356211
SNRPB	6628	small nuclear ribonucleoprotein polypeptides B and B1	histone pre-mRNA 3'end processing complex	Cellular component	-
CCL19	6363	chemokine (C-C motif) ligand 19	myeloid dendritic cell chemotaxis	Biological process	14592837
SETD1B	23067	SET domain containing 1B	RNA binding	Molecular function	-
EEF1D	1936	eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)	DNA binding	Molecular function	-
GHRHR	2692	growth hormone releasing hormone receptor	cAMP-mediated signaling	Biological process	7680413
ANGPT1	284	angiopoietin 1	protein localization to cell surface	Biological process	19615361
HERC6	55008	HECT and RLD domain containing E3 ubiquitin protein ligase family member 6	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	Biological process	-
MSX1	4487	msh homeobox 1	signal transduction involved in regulation of gene expression	Biological process	-
DCDC2C	728597	doublecortin domain containing 2C	intracellular signal transduction	Biological process	-
ADRBK1	156	adrenergic, beta, receptor kinase 1	tachykinin receptor signaling pathway	Biological process	17986524
CDK4	1019	cyclin-dependent kinase 4	organ regeneration	Biological process	-
RASA1	5921	RAS p21 protein activator (GTPase activating protein) 1	axon guidance	Biological process	-
RPP25	54913	ribonuclease P/MRP 25kDa subunit	microtubule organizing center	Cellular component	-
NEUROG2	63973	neurogenin 2	positive regulation of sequence-specific DNA binding transcription factor activity	Biological process	-
NOTCH1	4851	notch 1	negative regulation of calcium ion-dependent exocytosis	Biological process	-
GABBR2	9568	gamma-aminobutyric acid (GABA) B receptor, 2	negative regulation of adenylate cyclase activity	Biological process	10328880
IL6R	3570	interleukin 6 receptor	apical plasma membrane	Cellular component	16034137
TAB3	257397	TGF-beta activated kinase 1/MAP3K7 binding protein 3	toll-like receptor 5 signaling pathway	Biological process	-
ABCC6	368	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	response to drug	Biological process	8912525
XRCC3	7517	X-ray repair complementing defective repair in Chinese hamster cells 3	four-way junction DNA binding	Molecular function	20207730
TRIB1	10221	tribbles pseudokinase 1	negative regulation of lipopolysaccharide-mediated signaling pathway	Biological process	17452330
SLC1A5	6510	solute carrier family 1 (neutral amino acid transporter), member 5	membrane	Cellular component	19946888
STRA13	201254	stimulated by retinoic acid 13	condensed chromosome kinetochore	Cellular component	-
SHC1	6464	SHC (Src homology 2 domain containing) transforming protein 1	Ras protein signal transduction	Biological process	-
IL6	3569	interleukin 6	negative regulation of neuron death	Biological process	-
EFNB2	1948	ephrin-B2	viral process	Biological process	-
ALX1	8092	ALX homeobox 1	transcription from RNA polymerase II promoter	Biological process	8756334
C8orf22	492307	chromosome 8 open reading frame 22	multicellular organismal development	Biological process	-
FGF2	2247	fibroblast growth factor 2 (basic)	release of sequestered calcium ion into cytosol	Biological process	20011604
SIRT1	23411	sirtuin 1	positive regulation of cholesterol efflux	Biological process	-
SYTL2	54843	synaptotagmin-like 2	nucleus	Cellular component	-
CLSTN3	9746	calsyntenin 3	synaptic transmission, GABAergic	Biological process	-
YY1	7528	YY1 transcription factor	nuclear matrix	Cellular component	-
ZNF488	118738	zinc finger protein 488	DNA binding	Molecular function	-
HLA-DRB4	3126	major histocompatibility complex, class II, DR beta 4	antigen processing and presentation of exogenous peptide antigen via MHC class II	Biological process	-
SMC6	79677	structural maintenance of chromosomes 6	Smc5-Smc6 complex	Cellular component	18086888
FNDC3A	22862	fibronectin type III domain containing 3A	poly(A) RNA binding	Molecular function	22658674
IRF9	10379	interferon regulatory factor 9	sequence-specific DNA binding transcription factor activity	Molecular function	-
ITCH	83737	itchy E3 ubiquitin protein ligase	positive regulation of protein catabolic process	Biological process	-
ALDH18A1	5832	aldehyde dehydrogenase 18 family, member A1	glutamate-5-semialdehyde dehydrogenase activity	Molecular function	11092761
NXT1	29107	nuclear transport factor 2-like export factor 1	nuclear speck	Cellular component	-
PFKFB2	5208	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2	cytosol	Cellular component	-
BCAS3	54828	breast carcinoma amplified sequence 3	positive regulation of intracellular protein transport	Biological process	-
TAC1	6863	tachykinin, precursor 1	positive regulation of lymphocyte proliferation	Biological process	-
DSPP	1834	dentin sialophosphoprotein	cellular response to cell-matrix adhesion	Biological process	-
CDK5	1020	cyclin-dependent kinase 5	dendrite	Cellular component	-
PAX7	5081	paired box 7	negative regulation of apoptotic process	Biological process	10871843
PF4	5196	platelet factor 4	chemokine-mediated signaling pathway	Biological process	-
OR5T3	390154	olfactory receptor, family 5, subfamily T, member 3	integral component of membrane	Cellular component	-
AXIN2	8313	axin 2	cell cortex	Cellular component	-
ICAM1	3383	intercellular adhesion molecule 1	membrane to membrane docking	Biological process	12082081
CYP4X1	260293	cytochrome P450, family 4, subfamily X, polypeptide 1	heme binding	Molecular function	-
TATDN1	83940	TatD DNase domain containing 1	DNA catabolic process	Biological process	-
CDC26	246184	cell division cycle 26	nucleoplasm	Cellular component	-
PLAU	5328	plasminogen activator, urokinase	cell surface	Cellular component	18835034
CCNG1	900	cyclin G1	cell division	Biological process	-
AGT	183	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	positive regulation of membrane hyperpolarization	Biological process	15803439
OXT	5020	oxytocin/neurophysin I prepropeptide	terminal bouton	Cellular component	-
ESCO2	157570	establishment of sister chromatid cohesion N-acetyltransferase 2	hematopoietic progenitor cell differentiation	Biological process	-
SUPV3L1	6832	suppressor of var1, 3-like 1 (S. cerevisiae)	protein binding	Molecular function	17961633
STAG1	10274	stromal antigen 1	chromosome, centromeric region	Cellular component	-
LIG4	3981	ligase IV, DNA, ATP-dependent	DNA ligation involved in DNA recombination	Biological process	-
DNAJC21	134218	DnaJ (Hsp40) homolog, subfamily C, member 21	ribosome	Cellular component	16952052
LAMA2	3908	laminin, alpha 2	cell adhesion	Biological process	-
CYP4F12	66002	cytochrome P450, family 4, subfamily F, polypeptide 12	alkane 1-monooxygenase activity	Molecular function	-
IL18BP	10068	interleukin 18 binding protein	receptor antagonist activity	Molecular function	11890646
RDH11	51109	retinol dehydrogenase 11 (all-trans/9-cis/11-cis)	phototransduction, visible light	Biological process	-
RYR2	6262	ryanodine receptor 2 (cardiac)	smooth endoplasmic reticulum	Cellular component	-
ADORA1	134	adenosine A1 receptor	dendritic spine	Cellular component	-
CDCP1	64866	CUB domain containing protein 1	integral component of membrane	Cellular component	-
ACAA2	10449	acetyl-CoA acyltransferase 2	cholesterol biosynthetic process	Biological process	8241273
RNFT1	51136	ring finger protein, transmembrane 1	zinc ion binding	Molecular function	-
FOXRED2	80020	FAD-dependent oxidoreductase domain containing 2	protein binding	Molecular function	19706418
HIC1	3090	hypermethylated in cancer 1	metal ion binding	Molecular function	-
UBE2D3	7323	ubiquitin-conjugating enzyme E2D 3	protein autoubiquitination	Biological process	21068390
ADGRA2	25960	adhesion G protein-coupled receptor A2	cell surface	Cellular component	-
SMC5	23137	structural maintenance of chromosomes 5	positive regulation of mitotic metaphase/anaphase transition	Biological process	19502785
MAK	4117	male germ cell-associated kinase	protein binding	Molecular function	16951154
MTIF3	219402	mitochondrial translational initiation factor 3	mitochondrial translational initiation	Biological process	-
RNF4	6047	ring finger protein 4	androgen receptor binding	Molecular function	15572661
BOK	666	BCL2-related ovarian killer	male gonad development	Biological process	-
POF1B	79983	premature ovarian failure, 1B	actin binding	Molecular function	-
BAG5	9529	BCL2-associated athanogene 5	neuron death	Biological process	15603737
SLC25A27	9481	solute carrier family 25, member 27	integral component of membrane	Cellular component	-
CCL25	6370	chemokine (C-C motif) ligand 25	cell surface receptor signaling pathway	Biological process	10640743
SGPL1	8879	sphingosine-1-phosphate lyase 1	fibroblast migration	Biological process	-
MYLPF	29895	myosin light chain, phosphorylatable, fast skeletal muscle	skeletal muscle tissue development	Biological process	-
ETNK2	55224	ethanolamine kinase 2	multicellular organism growth	Biological process	-
RPL26	6154	ribosomal protein L26	cellular protein metabolic process	Biological process	-
CDC6	990	cell division cycle 6	negative regulation of cell proliferation	Biological process	9566895
BHMT2	23743	betaine--homocysteine S-methyltransferase 2	methylation	Biological process	-
DNAH1	25981	dynein, axonemal, heavy chain 1	axonemal dynein complex	Cellular component	9373155
PITX2	5308	paired-like homeodomain 2	myoblast fusion	Biological process	-
TLR2	7097	toll-like receptor 2	interleukin-10 production	Biological process	23826189
PGAM1	5223	phosphoglycerate mutase 1 (brain)	regulation of pentose-phosphate shunt	Biological process	12189148
HSF1	3297	heat shock transcription factor 1	protein phosphorylation	Biological process	-
HEXB	3074	hexosaminidase B (beta polypeptide)	lysosomal lumen	Cellular component	-
PDX1	3651	pancreatic and duodenal homeobox 1	negative regulation of type B pancreatic cell apoptotic process	Biological process	-
CITED1	4435	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1	response to estrogen	Biological process	17938205
FGFR2	2263	fibroblast growth factor receptor 2	mesenchymal cell proliferation involved in lung development	Biological process	-
GIP	2695	gastric inhibitory polypeptide	adult locomotory behavior	Biological process	-
THBS4	7060	thrombospondin 4	sarcoplasmic reticulum	Cellular component	-
KALRN	8997	kalirin, RhoGEF kinase	intracellular signal transduction	Biological process	-
UBA1	7317	ubiquitin-like modifier activating enzyme 1	cytoplasm	Cellular component	1376922
JAG2	3714	jagged 2	cell differentiation	Biological process	11549580
COL22A1	169044	collagen, type XXII, alpha 1	extracellular region	Cellular component	-
NEK2	4751	NIMA-related kinase 2	microtubule	Cellular component	-
DHX29	54505	DEAH (Asp-Glu-Ala-His) box polypeptide 29	ribosomal small subunit binding	Molecular function	23706745
AHR	196	aryl hydrocarbon receptor	response to toxic substance	Biological process	7961644
CAV2	858	caveolin 2	plasma membrane	Cellular component	12743374
RPS6KA3	6197	ribosomal protein S6 kinase, 90kDa, polypeptide 3	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Biological process	18402937
ARRB2	409	arrestin, beta 2	platelet activation	Biological process	-
VIMP	55829	VCP-interacting membrane selenoprotein	cell redox homeostasis	Biological process	15063746
KCNA1	3736	potassium channel, voltage gated shaker related subfamily A, member 1	detection of mechanical stimulus involved in sensory perception of touch	Biological process	-
PTH1R	5745	parathyroid hormone 1 receptor	aging	Biological process	-
OSBP	5007	oxysterol binding protein	protein domain specific binding	Molecular function	20178991
NOG	9241	noggin	notochord morphogenesis	Biological process	-
ADIPOQ	9370	adiponectin, C1Q and collagen domain containing	negative regulation of I-kappaB kinase/NF-kappaB signaling	Biological process	10982546
MADCAM1	8174	mucosal vascular addressin cell adhesion molecule 1	cell-matrix adhesion	Biological process	18308860
POLD3	10714	polymerase (DNA-directed), delta 3, accessory subunit	nucleotide-excision repair	Biological process	-
HSPE1	3336	heat shock 10kDa protein 1	protein folding	Biological process	-
OR10A5	144124	olfactory receptor, family 10, subfamily A, member 5	olfactory receptor activity	Molecular function	9787077
CLCN5	1184	chloride channel, voltage-sensitive 5	chloride channel activity	Molecular function	8559248
MCTP2	55784	multiple C2 domains, transmembrane 2	calcium-dependent phospholipid binding	Molecular function	15528213
MRPS12	6183	mitochondrial ribosomal protein S12	mitochondrial translational termination	Biological process	-
CD46	4179	CD46 molecule, complement regulatory protein	plasma membrane	Cellular component	-
LHX3	8022	LIM homeobox 3	zinc ion binding	Molecular function	-
ADIPOR1	51094	adiponectin receptor 1	integral component of membrane	Cellular component	12802337
RAB3A	5864	RAB3A, member RAS oncogene family	maintenance of presynaptic active zone structure	Biological process	-
GYPA	2993	glycophorin A (MNS blood group)	regulation of response to osmotic stress	Biological process	-
TNFSF8	944	tumor necrosis factor (ligand) superfamily, member 8	tumor necrosis factor receptor binding	Molecular function	-
PGAP1	80055	post-GPI attachment to proteins 1	myo-inositol transport	Biological process	-
UGP2	7360	UDP-glucose pyrophosphorylase 2	glycogen biosynthetic process	Biological process	-
BMPR2	659	bone morphogenetic protein receptor, type II (serine/threonine kinase)	neuronal cell body	Cellular component	-
IGFBP6	3489	insulin-like growth factor binding protein 6	insulin-like growth factor II binding	Molecular function	-
ZIC4	84107	Zic family member 4	DNA binding	Molecular function	-
PGF	5228	placental growth factor	positive regulation of endothelial cell proliferation	Biological process	-
PSMF1	9491	proteasome (prosome, macropain) inhibitor subunit 1 (PI31)	nucleoplasm	Cellular component	-
TH	7054	tyrosine hydroxylase	dopamine biosynthetic process	Biological process	12457228
PPIAL4C	653598	peptidylprolyl isomerase A (cyclophilin A)-like 4C	extracellular exosome	Cellular component	23533145
PIK3CA	5290	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	phosphatidylinositol 3-kinase complex	Cellular component	-
PIK3C2G	5288	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma	platelet activation	Biological process	-
RNF115	27246	ring finger protein 115	negative regulation of epidermal growth factor receptor signaling pathway	Biological process	23418353
CHMP3	51652	charged multivesicular body protein 3	protein binding	Molecular function	14505570
AGT	183	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	positive regulation of gap junction assembly	Biological process	17416596
PER1	5187	period circadian clock 1	transcription factor binding	Molecular function	-
HSBP1	3281	heat shock factor binding protein 1	nucleoplasm	Cellular component	-
CAV3	859	caveolin 3	plasma membrane repair	Biological process	-
COL7A1	1294	collagen, type VII, alpha 1	cell adhesion	Biological process	-
PPARG	5468	peroxisome proliferator-activated receptor gamma	regulation of cholesterol transporter activity	Biological process	17611579
ZBTB2	57621	zinc finger and BTB domain containing 2	regulation of transcription, DNA-templated	Biological process	-
GJA5	2702	gap junction protein, alpha 5, 40kDa	connexon complex	Cellular component	22247482
HES5	388585	hes family bHLH transcription factor 5	transcription, DNA-templated	Biological process	-
CDK5RAP2	55755	CDK5 regulatory subunit associated protein 2	regulation of spindle checkpoint	Biological process	19282672
ACAD9	28976	acyl-CoA dehydrogenase family, member 9	oxidation-reduction process	Biological process	-
DAB2IP	153090	DAB2 interacting protein	neuronal cell body	Cellular component	-
HTR2B	3357	5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled	cytoplasm	Cellular component	15925089
AKT1	207	v-akt murine thymoma viral oncogene homolog 1	protein serine/threonine/tyrosine kinase activity	Molecular function	22797923
CRISPLD2	83716	cysteine-rich secretory protein LCCL domain containing 2	extracellular matrix	Cellular component	-
ZBTB8OS	339487	zinc finger and BTB domain containing 8 opposite strand	tRNA splicing, via endonucleolytic cleavage and ligation	Biological process	24870230
CNDP2	55748	CNDP dipeptidase 2 (metallopeptidase M20 family)	dipeptidase activity	Molecular function	-
GPD1L	23171	glycerol-3-phosphate dehydrogenase 1-like	positive regulation of protein localization to cell surface	Biological process	17967977
EED	8726	embryonic ectoderm development	regulation of gene expression, epigenetic	Biological process	-
SPRR1A	6698	small proline-rich protein 1A	keratinization	Biological process	-
EIF4A1	1973	eukaryotic translation initiation factor 4A1	mRNA binding	Molecular function	3215517
ATP6V0D2	245972	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2	membrane	Cellular component	18752060
STMN2	11075	stathmin 2	protein binding	Molecular function	16189514
ADGRG5	221188	adhesion G protein-coupled receptor G5	plasma membrane	Cellular component	-
HEATR6	63897	HEAT repeat containing 6	poly(A) RNA binding	Molecular function	22681889
PER1	5187	period circadian clock 1	transcription, DNA-templated	Biological process	-
SFPQ	6421	splicing factor proline/glutamine-rich	core promoter binding	Molecular function	-
BFAR	51283	bifunctional apoptosis regulator	protein K63-linked ubiquitination	Biological process	21068390
CCT6A	908	chaperonin containing TCP1, subunit 6A (zeta 1)	acrosomal vesicle	Cellular component	-
STX4	6810	syntaxin 4	specific granule	Cellular component	18588921
TBX15	6913	T-box 15	embryonic cranial skeleton morphogenesis	Biological process	-
ADRA2B	151	adrenoceptor alpha 2B	activation of protein kinase B activity	Biological process	17215105
KAT7	11143	K(lysine) acetyltransferase 7	histone H4-K5 acetylation	Biological process	16387653
CSH2	1443	chorionic somatomammotropin hormone 2	hormone activity	Molecular function	-
BICD2	23299	bicaudal D homolog 2 (Drosophila)	Golgi apparatus	Cellular component	-
MED15	51586	mediator complex subunit 15	nucleus	Cellular component	-
HSD17B10	3028	hydroxysteroid (17-beta) dehydrogenase 10	lipid metabolic process	Biological process	9338779
HIST1H4F	8361	histone cluster 1, H4f	DNA binding	Molecular function	3035717
RC3H1	149041	ring finger and CCCH-type domains 1	cytoplasmic mRNA processing body assembly	Biological process	-
CTSH	1512	cathepsin H	cellular response to thyroid hormone stimulus	Biological process	21217776
DRD2	1813	dopamine receptor D2	integral component of plasma membrane	Cellular component	8413587
P4HA2	8974	prolyl 4-hydroxylase, alpha polypeptide II	L-ascorbic acid binding	Molecular function	-
FIS1	51024	fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)	positive regulation of cytosolic calcium ion concentration	Biological process	21183955
PKN1	5585	protein kinase N1	androgen receptor binding	Molecular function	12514133
ACER1	125981	alkaline ceramidase 1	epidermis development	Biological process	16477081
ZNF512	84450	zinc finger protein 512	metal ion binding	Molecular function	-
Sep-05	5413	septin 5	plasma membrane	Cellular component	10321247
CD160	11126	CD160 molecule	plasma membrane	Cellular component	-
RPS27A	6233	ribosomal protein S27a	negative regulation of transcription from RNA polymerase II promoter	Biological process	-
TF	7018	transferrin	ubiquitin protein ligase binding	Molecular function	-
IRX2	153572	iroquois homeobox 2	sequence-specific DNA binding	Molecular function	-
TRAF4	9618	TNF receptor-associated factor 4	respiratory tube development	Biological process	-
SPARC	6678	secreted protein, acidic, cysteine-rich (osteonectin)	nuclear matrix	Cellular component	15389586
DDIT3	1649	DNA-damage-inducible transcript 3	negative regulation of transcription from RNA polymerase II promoter	Biological process	11478948
H1F0	3005	H1 histone family, member 0	nucleoplasm	Cellular component	-
TUBB4B	10383	tubulin, beta 4B class IVb	cytosol	Cellular component	-
NEK1	4750	NIMA-related kinase 1	kinase activity	Molecular function	19158487
EIF3I	8668	eukaryotic translation initiation factor 3, subunit I	protein binding	Molecular function	14688252
OR4F21	441308	olfactory receptor, family 4, subfamily F, member 21	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
DAP3	7818	death associated protein 3	mitochondrion	Cellular component	-
ATXN2L	11273	ataxin 2-like	cytoplasmic stress granule	Cellular component	23209657
PRMT5	10419	protein arginine methyltransferase 5	ribonucleoprotein complex binding	Molecular function	17709427
TADA3	10474	transcriptional adaptor 3	protein binding	Molecular function	15383276
PAX3	5077	paired box 3	neural tube closure	Biological process	-
SYK	6850	spleen tyrosine kinase	regulation of tumor necrosis factor-mediated signaling pathway	Biological process	19151749
MOCS2	4338	molybdenum cofactor synthesis 2	nucleotide binding	Molecular function	-
RASGRF1	5923	Ras protein-specific guanine nucleotide-releasing factor 1	growth cone	Cellular component	-
IFNG	3458	interferon, gamma	positive regulation of cell proliferation	Biological process	-
CTR9	9646	CTR9, Paf1/RNA polymerase II complex component	nuclear speck	Cellular component	-
RABEPK	10244	Rab9 effector protein with kelch motifs	receptor-mediated endocytosis	Biological process	9230071
RHOB	388	ras homolog family member B	transformed cell apoptotic process	Biological process	-
BUB1	699	BUB1 mitotic checkpoint serine/threonine kinase	spindle assembly checkpoint	Biological process	19487456
KCNJ2	3759	potassium channel, inwardly rectifying subfamily J, member 2	inward rectifier potassium channel activity	Molecular function	11371347
TH	7054	tyrosine hydroxylase	response to electrical stimulus	Biological process	-
ELMOD3	84173	ELMO/CED-12 domain containing 3	stereocilium	Cellular component	-
ERVK-10	100616101	endogenous retrovirus group K, member 10	aspartic-type endopeptidase activity	Molecular function	-
PDXK	8566	pyridoxal (pyridoxine, vitamin B6) kinase	vitamin B6 metabolic process	Biological process	-
TCAP	8557	titin-cap	detection of muscle stretch	Biological process	12507422
HOXA11	3207	homeobox A11	transcription factor complex	Cellular component	-
SLC25A21	89874	solute carrier family 25 (mitochondrial oxoadipate carrier), member 21	lysine catabolic process	Biological process	-
ERCC8	1161	excision repair cross-complementation group 8	nucleotide-excision repair	Biological process	-
C5AR1	728	complement component 5a receptor 1	organ regeneration	Biological process	-
GNAT3	346562	guanine nucleotide binding protein, alpha transducing 3	platelet activation	Biological process	-
MRPL2	51069	mitochondrial ribosomal protein L2	mitochondrial inner membrane	Cellular component	-
PTPRC	5788	protein tyrosine phosphatase, receptor type, C	extracellular exosome	Cellular component	12519789
VDAC2	7417	voltage-dependent anion channel 2	negative regulation of intrinsic apoptotic signaling pathway	Biological process	-
KAT5	10524	K(lysine) acetyltransferase 5	positive regulation of protein acetylation	Biological process	24012345
SMARCB1	6598	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	ATP-dependent chromatin remodeling	Biological process	16217013
PPARD	5467	peroxisome proliferator-activated receptor delta	positive regulation of cell proliferation	Biological process	-
CRISP1	167	cysteine-rich secretory protein 1	extracellular space	Cellular component	8543280
WNT5B	81029	wingless-type MMTV integration site family, member 5B	neuron differentiation	Biological process	-
PDE6A	5145	phosphodiesterase 6A, cGMP-specific, rod, alpha	3',5'-cyclic-GMP phosphodiesterase activity	Molecular function	19946729
NEUROD1	4760	neuronal differentiation 1	positive regulation of transcription, DNA-templated	Biological process	-
KCNV1	27012	potassium channel, voltage gated modifier subfamily V, member 1	regulation of ion transmembrane transport	Biological process	-
RAPGEF3	10411	Rap guanine nucleotide exchange factor (GEF) 3	cAMP-mediated signaling	Biological process	16177794
PRDX5	25824	peroxiredoxin 5	positive regulation of collagen biosynthetic process	Biological process	15276323
TICAM2	353376	toll-like receptor adaptor molecule 2	negative regulation of chemokine (C-C motif) ligand 5 production	Biological process	19412184
KHDRBS1	10657	KH domain containing, RNA binding, signal transduction associated 1	poly(A) binding	Molecular function	21984414
KRT33B	3884	keratin 33B, type I	extracellular exosome	Cellular component	23533145
EGR1	1958	early growth response 1	cellular response to hypoxia	Biological process	-
RBM8A	9939	RNA binding motif protein 8A	mRNA binding	Molecular function	11030346
PTGES	9536	prostaglandin E synthase	small molecule metabolic process	Biological process	-
MED12	9968	mediator complex subunit 12	heart development	Biological process	-
MYF6	4618	myogenic factor 6 (herculin)	transcription from RNA polymerase II promoter	Biological process	-
TFDP2	7029	transcription factor Dp-2 (E2F dimerization partner 2)	sequence-specific DNA binding RNA polymerase II transcription factor activity	Molecular function	-
EPB41	2035	erythrocyte membrane protein band 4.1	spectrin	Cellular component	6894932
MESP1	55897	mesoderm posterior basic helix-loop-helix transcription factor 1	positive regulation of hepatocyte differentiation	Biological process	-
BRK1	55845	BRICK1, SCAR/WAVE actin-nucleating complex subunit	SCAR complex	Cellular component	21107423
CLCN4	1183	chloride channel, voltage-sensitive 4	chloride channel activity	Molecular function	10564087
PYCARD	29108	PYD and CARD domain containing	nucleolus	Cellular component	-
PDE3A	5139	phosphodiesterase 3A, cGMP-inhibited	positive regulation of oocyte development	Biological process	-
AQP1	358	aquaporin 1 (Colton blood group)	sarcolemma	Cellular component	17409744
KRT6C	286887	keratin 6C, type II	intermediate filament	Cellular component	9054461
PARP10	84875	poly (ADP-ribose) polymerase family, member 10	protein ADP-ribosylation	Biological process	23575687
NT5E	4907	5'-nucleotidase, ecto (CD73)	metal ion binding	Molecular function	-
LMNTD1	160492	lamin tail domain containing 1	cell proliferation	Biological process	-
TMED7	51014	transmembrane emp24 protein transport domain containing 7	Golgi apparatus	Cellular component	12237308
EGF	1950	epidermal growth factor	ERK1 and ERK2 cascade	Biological process	16314496
RYR1	6261	ryanodine receptor 1 (skeletal)	skeletal muscle fiber development	Biological process	-
ZNF763	284390	zinc finger protein 763	DNA binding	Molecular function	-
NKX2-6	137814	NK2 homeobox 6	sequence-specific DNA binding transcription factor activity	Molecular function	15649947
PSMF1	9491	proteasome (prosome, macropain) inhibitor subunit 1 (PI31)	mitotic cell cycle	Biological process	-
UBE2V2	7336	ubiquitin-conjugating enzyme E2 variant 2	nucleus	Cellular component	16129784
ABCG8	64241	ATP-binding cassette, sub-family G (WHITE), member 8	response to nutrient	Biological process	-
PFKFB2	5208	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2	dephosphorylation	Biological process	-
HUS1	3364	HUS1 checkpoint homolog (S. pombe)	DNA repair	Biological process	9872989
ASB12	142689	ankyrin repeat and SOCS box containing 12	protein ubiquitination	Biological process	-
ERC2	26059	ELKS/RAB6-interacting/CAST family member 2	protein binding	Molecular function	12923177
RAB23	51715	RAB23, member RAS oncogene family	intracellular protein transport	Biological process	-
INS	3630	insulin	Golgi lumen	Cellular component	-
HRASLS2	54979	HRAS-like suppressor 2	hydrolase activity	Molecular function	-
ALOX5	240	arachidonate 5-lipoxygenase	leukotriene production involved in inflammatory response	Biological process	-
JUP	3728	junction plakoglobin	regulation of ventricular cardiac muscle cell action potential	Biological process	17924338
TPH2	121278	tryptophan hydroxylase 2	cellular response to lithium ion	Biological process	-
NDUFA7	4701	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa	mitochondrial respiratory chain complex I	Cellular component	9878551
MCM2	4171	minichromosome maintenance complex component 2	protein binding	Molecular function	11095689
ATP7A	538	ATPase, Cu++ transporting, alpha polypeptide	response to zinc ion	Biological process	-
RILPL2	196383	Rab interacting lysosomal protein-like 2	identical protein binding	Molecular function	16189514
TMEM165	55858	transmembrane protein 165	cellular calcium ion homeostasis	Biological process	23569283
OR2AE1	81392	olfactory receptor, family 2, subfamily AE, member 1	olfactory receptor activity	Molecular function	-
SCARB1	949	scavenger receptor class B, member 1	lipopolysaccharide transport	Biological process	12651854
OTULIN	90268	OTU deubiquitinase with linear linkage specificity	negative regulation of NF-kappaB transcription factor activity	Biological process	23806334
RRAGA	10670	Ras-related GTP binding A	Golgi apparatus	Cellular component	-
DEF6	50619	differentially expressed in FDCP 6 homolog (mouse)	cell-cell junction	Cellular component	-
SLC6A16	28968	solute carrier family 6, member 16	neurotransmitter transport	Biological process	11112352
ITIH1	3697	inter-alpha-trypsin inhibitor heavy chain 1	calcium ion binding	Molecular function	2446322
SQRDL	58472	sulfide quinone reductase-like (yeast)	hydrogen sulfide metabolic process	Biological process	22852582
GALNT11	63917	polypeptide N-acetylgalactosaminyltransferase 11	protein O-linked glycosylation via threonine	Biological process	24226769
MTFP1	51537	mitochondrial fission process 1	apoptotic process	Biological process	-
GHRL	51738	ghrelin/obestatin prepropeptide	regulation of cell proliferation	Biological process	15564328
SNF8	11267	SNF8, ESCRT-II complex subunit	regulation of multivesicular body size involved in endosome transport	Biological process	17714434
C1QL4	338761	complement component 1, q subcomponent-like 4	negative regulation of fibroblast proliferation	Biological process	-
ITGA1	3672	integrin, alpha 1	membrane raft	Cellular component	-
HLA-DQA1	3117	major histocompatibility complex, class II, DQ alpha 1	trans-Golgi network membrane	Cellular component	-
PDCD11	22984	programmed cell death 11	protein binding	Molecular function	14624448
ZNF774	342132	zinc finger protein 774	transcription, DNA-templated	Biological process	-
HERC2	8924	HECT and RLD domain containing E3 ubiquitin protein ligase 2	SUMO binding	Molecular function	22508508
VEGFA	7422	vascular endothelial growth factor A	coronary vein morphogenesis	Biological process	-
SLC1A4	6509	solute carrier family 1 (glutamate/neutral amino acid transporter), member 4	threonine transport	Biological process	8340364
AXIN1	8312	axin 1	lateral plasma membrane	Cellular component	12072559
HCRTR2	3062	hypocretin (orexin) receptor 2	orexin receptor activity	Molecular function	-
ERP27	121506	endoplasmic reticulum protein 27	response to endoplasmic reticulum stress	Biological process	-
TCF12	6938	transcription factor 12	bHLH transcription factor binding	Molecular function	21828274
PCDHA3	56145	protocadherin alpha 3	cell adhesion	Biological process	10380929
DAB2	1601	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)	lysosomal membrane	Cellular component	-
RFC2	5982	replication factor C (activator 1) 2, 40kDa	error-free translesion synthesis	Biological process	-
ADAMTS16	170690	ADAM metallopeptidase with thrombospondin type 1 motif, 16	branching involved in ureteric bud morphogenesis	Biological process	-
CLEC2D	29121	C-type lectin domain family 2, member D	cell surface	Cellular component	20843815
SUV39H1	6839	suppressor of variegation 3-9 homolog 1 (Drosophila)	negative regulation of transcription from RNA polymerase II promoter	Biological process	21402781
C6orf203	51250	chromosome 6 open reading frame 203	mitochondrion	Cellular component	20833797
EIF4E	1977	eukaryotic translation initiation factor 4E	eukaryotic translation initiation factor 4F complex	Cellular component	22578813
ZFAND6	54469	zinc finger, AN1-type domain 6	cellular response to tumor necrosis factor	Biological process	21810480
PAFAH1B1	5048	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	negative regulation of neuron projection development	Biological process	-
CDKN2D	1032	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	negative regulation of cell growth	Biological process	10208428
BRE	9577	brain and reproductive organ-expressed (TNFRSF1A modulator)	cytoplasm	Cellular component	-
PLCB1	23236	phospholipase C, beta 1 (phosphoinositide-specific)	protein homodimerization activity	Molecular function	-
PIP5K1C	23396	phosphatidylinositol-4-phosphate 5-kinase, type I, gamma	actin cytoskeleton organization	Biological process	19889969
DDX1	1653	DEAD (Asp-Glu-Ala-Asp) box helicase 1	ribonucleoprotein complex	Cellular component	18809582
RASGRF1	5923	Ras protein-specific guanine nucleotide-releasing factor 1	regulation of N-methyl-D-aspartate selective glutamate receptor activity	Biological process	-
IRAK1	3654	interleukin-1 receptor-associated kinase 1	transmembrane receptor protein serine/threonine kinase signaling pathway	Biological process	11397809
GOLPH3	64083	golgi phosphoprotein 3 (coat-protein)	phosphatidylinositol-4-phosphate binding	Molecular function	19837035
PACSIN2	11252	protein kinase C and casein kinase substrate in neurons 2	identical protein binding	Molecular function	16189514
FOXN2	3344	forkhead box N2	regulation of transcription, DNA-templated	Biological process	-
APLF	200558	aprataxin and PNKP like factor	3'-5' exonuclease activity	Molecular function	17396150
RBMY1D	378949	RNA binding motif protein, Y-linked, family 1, member D	RNA splicing	Biological process	-
MRPS21	54460	mitochondrial ribosomal protein S21	mitochondrial small ribosomal subunit	Cellular component	11279123
PSMD3	5709	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	innate immune response	Biological process	-
NR1D1	9572	nuclear receptor subfamily 1, group D, member 1	regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter	Biological process	18006707
PIGK	10026	phosphatidylinositol glycan anchor biosynthesis, class K	C-terminal protein lipidation	Biological process	-
CYP1A1	1543	cytochrome P450, family 1, subfamily A, polypeptide 1	flavonoid metabolic process	Biological process	-
ESRRB	2103	estrogen-related receptor beta	gene expression	Biological process	-
SOX9	6662	SRY (sex determining region Y)-box 9	sequence-specific DNA binding transcription factor activity	Molecular function	8640233
PRKACB	5567	protein kinase, cAMP-dependent, catalytic, beta	negative regulation of meiotic cell cycle	Biological process	-
NDUFS2	4720	NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)	NADH dehydrogenase (ubiquinone) activity	Molecular function	9647766
TDGF1	6997	teratocarcinoma-derived growth factor 1	perinuclear region of cytoplasm	Cellular component	-
CTNNB1	1499	catenin (cadherin-associated protein), beta 1, 88kDa	SMAD binding	Molecular function	18593713
DIAPH2	1730	diaphanous-related formin 2	mitochondrion	Cellular component	-
RUNX2	860	runt-related transcription factor 2	BMP signaling pathway	Biological process	-
OBFC1	79991	oligonucleotide/oligosaccharide-binding fold containing 1	telomere maintenance via telomere lengthening	Biological process	19648609
EIF4E3	317649	eukaryotic translation initiation factor 4E family member 3	regulation of translation	Biological process	-
NME8	51314	NME/NM23 family member 8	cytoplasm	Cellular component	-
CWC15	51503	CWC15 spliceosome-associated protein	nucleoplasm	Cellular component	-
TXK	7294	TXK tyrosine kinase	receptor binding	Molecular function	-
SNX33	257364	sorting nexin 33	phosphatidylinositol binding	Molecular function	-
POLE	5426	polymerase (DNA directed), epsilon, catalytic subunit	nucleus	Cellular component	16762037
CBX8	57332	chromobox homolog 8	histone ubiquitination	Biological process	-
CELF5	60680	CUGBP, Elav-like family member 5	nucleotide binding	Molecular function	-
RPS4X	6191	ribosomal protein S4, X-linked	positive regulation of cell proliferation	Biological process	1795030
CELSR2	1952	cadherin, EGF LAG seven-pass G-type receptor 2	neural plate anterior/posterior regionalization	Biological process	-
FANCD2	2177	Fanconi anemia, complementation group D2	DNA repair	Biological process	-
TBX19	9095	T-box 19	regulation of transcription from RNA polymerase II promoter	Biological process	9888994
SLC7A8	23428	solute carrier family 7 (amino acid transporter light chain, L system), member 8	neutral amino acid transport	Biological process	-
MC3R	4159	melanocortin 3 receptor	melanocyte-stimulating hormone receptor activity	Molecular function	19743876
TCF7L2	6934	transcription factor 7-like 2 (T-cell specific, HMG-box)	maintenance of DNA repeat elements	Biological process	18755497
SNCA	6622	synuclein, alpha (non A4 component of amyloid precursor)	nucleus	Cellular component	12406186
NR1I3	9970	nuclear receptor subfamily 1, group I, member 3	intracellular receptor signaling pathway	Biological process	8114692
SRC	6714	SRC proto-oncogene, non-receptor tyrosine kinase	branching involved in mammary gland duct morphogenesis	Biological process	-
ITGAV	3685	integrin, alpha V	negative regulation of lipid storage	Biological process	15215180
MUC5AC	4586	mucin 5AC, oligomeric mucus/gel-forming	extracellular exosome	Cellular component	19199708
ITGA1	3672	integrin, alpha 1	extracellular exosome	Cellular component	19056867
ABO	28	ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)	fucosylgalactoside 3-alpha-galactosyltransferase activity	Molecular function	-
MTAP	4507	methylthioadenosine phosphorylase	phosphorylase activity	Molecular function	-
UGT2B11	10720	UDP glucuronosyltransferase 2 family, polypeptide B11	flavonoid biosynthetic process	Biological process	-
GNAS	2778	GNAS complex locus	extracellular region	Cellular component	-
TF	7018	transferrin	coated pit	Cellular component	12857860
HIST1H3D	8351	histone cluster 1, H3d	nucleus	Cellular component	21630459
PRKACA	5566	protein kinase, cAMP-dependent, catalytic, alpha	cellular response to glucagon stimulus	Biological process	-
NCOR1	9611	nuclear receptor corepressor 1	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	Biological process	-
ATP2A2	488	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	endoplasmic reticulum membrane	Cellular component	-
EYA1	2138	EYA transcriptional coactivator and phosphatase 1	transcription, DNA-templated	Biological process	-
GPX2	2877	glutathione peroxidase 2	glutathione peroxidase activity	Molecular function	-
RPS5	6193	ribosomal protein S5	translational termination	Biological process	-
CR2	1380	complement component (3d/Epstein Barr virus) receptor 2	complement receptor activity	Molecular function	2827171
PSEN1	5663	presenilin 1	hematopoietic progenitor cell differentiation	Biological process	-
CYP27B1	1594	cytochrome P450, family 27, subfamily B, polypeptide 1	mitochondrial outer membrane	Cellular component	-
PRDX5	25824	peroxiredoxin 5	cytoplasmic vesicle	Cellular component	10095767
CRX	1406	cone-rod homeobox	circadian rhythm	Biological process	-
RGPD1	400966	RANBP2-like and GRIP domain containing 1	intracellular	Cellular component	-
UGT2B28	54490	UDP glucuronosyltransferase 2 family, polypeptide B28	xenobiotic metabolic process	Biological process	11300766
TLR4	7099	toll-like receptor 4	detection of lipopolysaccharide	Biological process	19252480
SLC2A2	6514	solute carrier family 2 (facilitated glucose transporter), member 2	transmembrane transport	Biological process	-
STRADA	92335	STE20-related kinase adaptor alpha	protein serine/threonine kinase activator activity	Molecular function	19892943
POLR3B	55703	polymerase (RNA) III (DNA directed) polypeptide B	metal ion binding	Molecular function	-
CTCFL	140690	CCCTC-binding factor (zinc finger protein)-like	transcription regulatory region DNA binding	Molecular function	18413740
IQCB1	9657	IQ motif containing B1	extracellular exosome	Cellular component	18570454
SRSF6	6431	serine/arginine-rich splicing factor 6	alternative mRNA splicing, via spliceosome	Biological process	22767602
CDY1	9085	chromodomain protein, Y-linked, 1	nucleus	Cellular component	18450745
LRP5	4041	low density lipoprotein receptor-related protein 5	bone marrow development	Biological process	17680723
SLC34A1	6569	solute carrier family 34 (type II sodium/phosphate cotransporter), member 1	perinuclear region of cytoplasm	Cellular component	-
PHF20L1	51105	PHD finger protein 20-like 1	zinc ion binding	Molecular function	-
PICALM	8301	phosphatidylinositol binding clathrin assembly protein	clathrin adaptor activity	Molecular function	23589030
CYP17A1	1586	cytochrome P450, family 17, subfamily A, polypeptide 1	iron ion binding	Molecular function	-
CDK11B	984	cyclin-dependent kinase 11B	apoptotic process	Biological process	9750192
TNFSF4	7292	tumor necrosis factor (ligand) superfamily, member 4	positive regulation of interleukin-13 production	Biological process	-
ISG20	3669	interferon stimulated exonuclease gene 20kDa	DNA catabolic process, exonucleolytic	Biological process	11401564
FABP4	2167	fatty acid binding protein 4, adipocyte	small molecule metabolic process	Biological process	-
HSD17B6	8630	hydroxysteroid (17-beta) dehydrogenase 6	testosterone dehydrogenase (NAD+) activity	Molecular function	-
CIITA	4261	class II, major histocompatibility complex, transactivator	protein C-terminus binding	Molecular function	16600381
FEM1B	10116	fem-1 homolog b (C. elegans)	apoptotic process	Biological process	10623617
CAMK4	814	calcium/calmodulin-dependent protein kinase IV	nucleocytoplasmic transport	Biological process	-
BMPR1A	657	bone morphogenetic protein receptor, type IA	positive regulation of mesenchymal cell proliferation	Biological process	-
DUSP3	1845	dual specificity phosphatase 3	inactivation of MAPK activity	Biological process	16604064
BCAN	63827	brevican	extracellular matrix disassembly	Biological process	-
GPAT2	150763	glycerol-3-phosphate acyltransferase 2, mitochondrial	glycerophospholipid biosynthetic process	Biological process	-
C3AR1	719	complement component 3a receptor 1	complement component C3a receptor activity	Molecular function	8765043
OAZ3	51686	ornithine decarboxylase antizyme 3	ankyrin repeat binding	Molecular function	-
CLCA2	9635	chloride channel accessory 2	basal plasma membrane	Cellular component	-
APOC3	345	apolipoprotein C-III	retinoid metabolic process	Biological process	-
B9D1	27077	B9 protein domain 1	in utero embryonic development	Biological process	-
PLK1	5347	polo-like kinase 1	mitotic nuclear division	Biological process	18477460
PSPC1	55269	paraspeckle component 1	regulation of circadian rhythm	Biological process	-
SGPL1	8879	sphingosine-1-phosphate lyase 1	luteinization	Biological process	-
CENPV	201161	centromere protein V	cell division	Biological process	-
DDX6	1656	DEAD (Asp-Glu-Ala-Asp) box helicase 6	poly(A) RNA binding	Molecular function	22658674
N4BP2L2	10443	NEDD4 binding protein 2-like 2	transcriptional repressor complex	Cellular component	19506020
ZKSCAN3	80317	zinc finger with KRAB and SCAN domains 3	transcription, DNA-templated	Biological process	-
HEYL	26508	hes-related family bHLH transcription factor with YRPW motif-like	proximal tubule development	Biological process	-
UBE2K	3093	ubiquitin-conjugating enzyme E2K	ubiquitin protein ligase binding	Molecular function	16714285
KCNC1	3746	potassium channel, voltage gated Shaw related subfamily C, member 1	voltage-gated potassium channel activity	Molecular function	8449507
KRT19	3880	keratin 19, type I	plasma membrane	Cellular component	23377137
TPM1	7168	tropomyosin 1 (alpha)	structural constituent of muscle	Molecular function	8205619
UBE2D1	7321	ubiquitin-conjugating enzyme E2D 1	cytosol	Cellular component	-
CEACAM1	634	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	cell migration	Biological process	15687237
SIGLEC6	946	sialic acid binding Ig-like lectin 6	integral component of plasma membrane	Cellular component	9465907
TMEM119	338773	transmembrane protein 119	molecular_function	Molecular function	-
OXSR1	9943	oxidative stress responsive 1	activation of protein kinase activity	Biological process	-
CYP11B2	1585	cytochrome P450, family 11, subfamily B, polypeptide 2	corticosterone 18-monooxygenase activity	Molecular function	-
DIO3	1735	deiodinase, iodothyronine, type III	plasma membrane	Cellular component	-
ITGB1BP1	9270	integrin beta 1 binding protein 1	negative regulation of protein binding	Biological process	12473654
ZNF263	10127	zinc finger protein 263	microtubule cytoskeleton	Cellular component	-
PRR7	80758	proline rich 7 (synaptic)	postsynaptic membrane	Cellular component	-
SLC25A17	10478	solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17	fatty acid alpha-oxidation	Biological process	-
NAGLU	4669	N-acetylglucosaminidase, alpha	lysosome organization	Biological process	-
RAB22A	57403	RAB22A, member RAS oncogene family	Rab protein signal transduction	Biological process	-
PSAP	5660	prosaposin	epithelial cell differentiation involved in prostate gland development	Biological process	-
UBE2J2	118424	ubiquitin-conjugating enzyme E2, J2	integral component of membrane	Cellular component	-
ELOVL6	79071	ELOVL fatty acid elongase 6	cellular lipid metabolic process	Biological process	-
CSNK1D	1453	casein kinase 1, delta	circadian regulation of gene expression	Biological process	-
CLPTM1L	81037	CLPTM1-like	membrane	Cellular component	19946888
PKDREJ	10343	polycystin (PKD) family receptor for egg jelly	acrosome reaction	Biological process	9949214
MAGEA8	4107	melanoma antigen family A8	protein binding	Molecular function	25416956
CHRNB4	1143	cholinergic receptor, nicotinic, beta 4 (neuronal)	regulation of neurotransmitter secretion	Biological process	11742001
ECE2	9718	endothelin converting enzyme 2	metal ion binding	Molecular function	-
NUMA1	4926	nuclear mitotic apparatus protein 1	cell division	Biological process	-
MBTD1	54799	mbt domain containing 1	zinc ion binding	Molecular function	-
COX4I1	1327	cytochrome c oxidase subunit IV isoform 1	protein binding	Molecular function	23260140
TOR1A	1861	torsin family 1, member A (torsin A)	regulation of protein localization to cell surface	Biological process	15505207
DUSP6	1848	dual specificity phosphatase 6	peptidyl-tyrosine dephosphorylation	Biological process	8670865
FADD	8772	Fas (TNFRSF6)-associated via death domain	positive regulation of transcription from RNA polymerase II promoter	Biological process	16127453
TLR2	7097	toll-like receptor 2	toll-like receptor signaling pathway	Biological process	-
GHRL	51738	ghrelin/obestatin prepropeptide	positive regulation of insulin secretion	Biological process	-
AUTS2	26053	autism susceptibility candidate 2	positive regulation of transcription from RNA polymerase II promoter	Biological process	25519132
LDLRAP1	26119	low density lipoprotein receptor adaptor protein 1	clathrin binding	Molecular function	12221107
LGALS3BP	3959	lectin, galactoside-binding, soluble, 3 binding protein	blood microparticle	Cellular component	22516433
SLC1A4	6509	solute carrier family 1 (glutamate/neutral amino acid transporter), member 4	L-cystine transport	Biological process	8340364
MAEL	84944	maelstrom spermatogenic transposon silencer	perinuclear region of cytoplasm	Cellular component	-
PSMB3	5691	proteasome (prosome, macropain) subunit, beta type, 3	gene expression	Biological process	-
NR1H3	10062	nuclear receptor subfamily 1, group H, member 3	gene expression	Biological process	-
TBRG1	84897	transforming growth factor beta regulator 1	protein stabilization	Biological process	17110379
UGT1A1	54658	UDP glucuronosyltransferase 1 family, polypeptide A1	cellular response to glucocorticoid stimulus	Biological process	-
TAF7	6879	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa	transcription factor TFIID complex	Cellular component	14580349
NCOA3	8202	nuclear receptor coactivator 3	extracellular exosome	Cellular component	18570454
LIN28A	79727	lin-28 homolog A (C. elegans)	RNA 3'-end processing	Biological process	18951094
HIST1H3B	8358	histone cluster 1, H3b	DNA binding	Molecular function	-
PARK7	11315	parkinson protein 7	regulation of mitochondrial membrane potential	Biological process	23743200
UQCRFS1	7386	ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1	response to hormone	Biological process	-
ERBB2	2064	erb-b2 receptor tyrosine kinase 2	peptidyl-tyrosine phosphorylation	Biological process	-
RPL39	6170	ribosomal protein L39	translational initiation	Biological process	-
CSNK1G1	53944	casein kinase 1, gamma 1	Wnt signaling pathway	Biological process	-
BEX1	55859	brain expressed, X-linked 1	transcription factor complex	Cellular component	16314316
KLC1	3831	kinesin light chain 1	viral process	Biological process	-
KIF16B	55614	kinesin family member 16B	ATP-dependent microtubule motor activity, plus-end-directed	Molecular function	15882625
MAPK11	5600	mitogen-activated protein kinase 11	MAP kinase activity	Molecular function	10330143
SCAMP1	9522	secretory carrier membrane protein 1	trans-Golgi network	Cellular component	15840657
RAB3D	9545	RAB3D, member RAS oncogene family	myosin V binding	Molecular function	24006491
NMUR2	56923	neuromedin U receptor 2	protein binding	Molecular function	25416956
PLEKHA8P1	51054	pleckstrin homology domain containing, family A member 8 pseudogene 1	glycolipid transport	Biological process	-
CNR1	1268	cannabinoid receptor 1 (brain)	response to ethanol	Biological process	-
IKBKG	8517	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	MyD88-independent toll-like receptor signaling pathway	Biological process	-
GLRA2	2742	glycine receptor, alpha 2	integral component of plasma membrane	Cellular component	2155780
H2AFY	9555	H2A histone family, member Y	regulation of cell growth	Biological process	24071584
SERPINA2	390502	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene)	protein binding	Molecular function	23826168
UBXN2A	165324	UBX domain protein 2A	Golgi organization	Biological process	-
CEP250	11190	centrosomal protein 250kDa	mitotic cell cycle	Biological process	-
SFPQ	6421	splicing factor proline/glutamine-rich	transcription, DNA-templated	Biological process	-
PARD6B	84612	par-6 family cell polarity regulator beta	apical part of cell	Cellular component	-
NUP37	79023	nucleoporin 37kDa	protein sumoylation	Biological process	-
ADCY6	112	adenylate cyclase 6	plasma membrane	Cellular component	-
HTR3B	9177	5-hydroxytryptamine (serotonin) receptor 3B, ionotropic	serotonin-activated cation-selective channel activity	Molecular function	-
PCMT1	5110	protein-L-isoaspartate (D-aspartate) O-methyltransferase	endoplasmic reticulum	Cellular component	1339271
ASGR1	432	asialoglycoprotein receptor 1	integral component of plasma membrane	Cellular component	10734069
ACTR3	10096	ARP3 actin-related protein 3 homolog (yeast)	spindle localization	Biological process	-
PKN2	5586	protein kinase N2	apoptotic process	Biological process	-
OR5AR1	219493	olfactory receptor, family 5, subfamily AR, member 1 (gene/pseudogene)	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
SNF8	11267	SNF8, ESCRT-II complex subunit	nucleus	Cellular component	23171048
SEMA6D	80031	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	positive regulation of smooth muscle cell migration	Biological process	-
GZMA	3001	granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)	positive regulation of apoptotic process	Biological process	12524539
XIAP	331	X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase	regulation of innate immune response	Biological process	21447281
ATIC	471	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	protein homodimerization activity	Molecular function	14756553
MXD4	10608	MAX dimerization protein 4	transcription, DNA-templated	Biological process	-
FAM175A	84142	family with sequence similarity 175, member A	protein binding	Molecular function	17525340
UCN3	114131	urocortin 3	varicosity	Cellular component	-
DSPP	1834	dentin sialophosphoprotein	proteinaceous extracellular matrix	Cellular component	-
DLX6	1750	distal-less homeobox 6	embryonic limb morphogenesis	Biological process	-
BAZ2A	11176	bromodomain adjacent to zinc finger domain, 2A	histone deacetylation	Biological process	-
ZNF385A	25946	zinc finger protein 385A	regulation of transcription, DNA-templated	Biological process	-
MED1	5469	mediator complex subunit 1	embryonic placenta development	Biological process	-
SLC11A2	4891	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2	heme biosynthetic process	Biological process	-
PEX6	5190	peroxisomal biogenesis factor 6	protein complex binding	Molecular function	16854980
GAP43	2596	growth associated protein 43	cell junction	Cellular component	-
RAB3B	5865	RAB3B, member RAS oncogene family	regulation of exocytosis	Biological process	-
ZNF438	220929	zinc finger protein 438	transcription, DNA-templated	Biological process	-
CLEC11A	6320	C-type lectin domain family 11, member A	positive regulation of cell proliferation	Biological process	11920266
C5orf28	64417	chromosome 5 open reading frame 28	integral component of membrane	Cellular component	-
GRM3	2913	glutamate receptor, metabotropic 3	axon	Cellular component	-
ABHD12	26090	abhydrolase domain containing 12	phosphatidylserine catabolic process	Biological process	-
CEP126	57562	centrosomal protein 126kDa	cilium assembly	Biological process	24867236
HAO1	54363	hydroxyacid oxidase (glycolate oxidase) 1	small molecule metabolic process	Biological process	-
CLASRP	11129	CLK4-associating serine/arginine rich protein	mRNA processing	Biological process	-
NFYB	4801	nuclear transcription factor Y, beta	transcription, DNA-templated	Biological process	-
RFX8	731220	RFX family member 8, lacking RFX DNA binding domain	transcription, DNA-templated	Biological process	-
DHX16	8449	DEAH (Asp-Glu-Ala-His) box polypeptide 16	poly(A) RNA binding	Molecular function	22658674
MME	4311	membrane metallo-endopeptidase	integral component of plasma membrane	Cellular component	2521388
EGF	1950	epidermal growth factor	positive regulation of phosphorylation	Biological process	15611079
IL22RA1	58985	interleukin 22 receptor, alpha 1	defense response to Gram-negative bacterium	Biological process	-
CLDN4	1364	claudin 4	identical protein binding	Molecular function	-
ZDHHC24	254359	zinc finger, DHHC-type containing 24	protein-cysteine S-palmitoyltransferase activity	Molecular function	-
GNAS	2778	GNAS complex locus	nucleus	Cellular component	20862257
KDM1A	23028	lysine (K)-specific demethylase 1A	small GTPase mediated signal transduction	Biological process	-
ARFGAP2	84364	ADP-ribosylation factor GTPase activating protein 2	plasma membrane	Cellular component	-
CST9	128822	cystatin 9 (testatin)	extracellular region	Cellular component	-
TFAP2B	7021	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	retina layer formation	Biological process	20607706
ETNK1	55500	ethanolamine kinase 1	cytoplasm	Cellular component	-
KCNC3	3748	potassium channel, voltage gated Shaw related subfamily C, member 3	protein homooligomerization	Biological process	-
FOXP4	116113	forkhead box P4	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	-
CARM1	10498	coactivator-associated arginine methyltransferase 1	ligand-dependent nuclear receptor transcription coactivator activity	Molecular function	-
ZNF430	80264	zinc finger protein 430	substantia nigra development	Biological process	22926577
STARD8	9754	StAR-related lipid transfer (START) domain containing 8	regulation of small GTPase mediated signal transduction	Biological process	-
PTEN	5728	phosphatase and tensin homolog	prepulse inhibition	Biological process	-
FOXC2	2303	forkhead box C2	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	Molecular function	20956529
SLC4A5	57835	solute carrier family 4 (sodium bicarbonate cotransporter), member 5	plasma membrane	Cellular component	-
CD48	962	CD48 molecule	anchored component of membrane	Cellular component	-
ABCB5	340273	ATP-binding cassette, sub-family B (MDR/TAP), member 5	compound eye corneal lens development	Biological process	-
INO80	54617	INO80 complex subunit	cell division	Biological process	-
RTCA	8634	RNA 3'-terminal phosphate cyclase	ATP binding	Molecular function	-
SSTR5	6755	somatostatin receptor 5	neuron projection	Cellular component	-
EAF2	55840	ELL associated factor 2	transcription elongation factor complex	Cellular component	22195968
FRZB	2487	frizzled-related protein	extracellular space	Cellular component	22261194
PRKAA2	5563	protein kinase, AMP-activated, alpha 2 catalytic subunit	histone serine kinase activity	Molecular function	-
DDX23	9416	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23	ATP-dependent RNA helicase activity	Molecular function	9409622
SRI	6717	sorcin	regulation of calcium ion transport	Biological process	12754254
DYNLT1	6993	dynein, light chain, Tctex-type 1	regulation of cytoskeleton organization	Biological process	-
HM13	81502	histocompatibility (minor) 13	protein homodimerization activity	Molecular function	15385547
ATP1A1	476	ATPase, Na+/K+ transporting, alpha 1 polypeptide	chaperone binding	Molecular function	10636900
RNF149	284996	ring finger protein 149	integral component of membrane	Cellular component	-
KIDINS220	57498	kinase D-interacting substrate, 220kDa	cytoplasmic transport	Biological process	-
FIS1	51024	fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)	release of cytochrome c from mitochondria	Biological process	19864424
PRSS36	146547	protease, serine, 36	proteolysis	Biological process	-
PEX16	9409	peroxisomal biogenesis factor 16	peroxisome membrane biogenesis	Biological process	12223482
FMO3	2328	flavin containing monooxygenase 3	drug metabolic process	Biological process	-
AGTR2	186	angiotensin II receptor, type 2	aldosterone secretion	Biological process	-
TYMS	7298	thymidylate synthetase	mitotic cell cycle	Biological process	-
SLC32A1	140679	solute carrier family 32 (GABA vesicular transporter), member 1	dendrite	Cellular component	12115694
KCNJ11	3767	potassium channel, inwardly rectifying subfamily J, member 11	cellular response to tumor necrosis factor	Biological process	-
CPT1B	1375	carnitine palmitoyltransferase 1B (muscle)	integral component of membrane	Cellular component	-
NOTCH2	4853	notch 2	membrane	Cellular component	19946888
FAN1	22909	FANCD2/FANCI-associated nuclease 1	magnesium ion binding	Molecular function	20603016
CLECL1	160365	C-type lectin-like 1	carbohydrate binding	Molecular function	-
CNGA1	1259	cyclic nucleotide gated channel alpha 1	protein binding	Molecular function	20890309
GAS7	8522	growth arrest-specific 7	actin filament polymerization	Biological process	-
EIF5A	1984	eukaryotic translation initiation factor 5A	extracellular exosome	Cellular component	23376485
MYZAP	100820829	myocardial zonula adherens protein	extrinsic component of cytoplasmic side of plasma membrane	Cellular component	-
SERPINF1	5176	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1	negative regulation of inflammatory response	Biological process	-
NUDT16L1	84309	nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1	metabolic process	Biological process	-
MBOAT1	154141	membrane bound O-acyltransferase domain containing 1	phosphatidylethanolamine acyl-chain remodeling	Biological process	-
PRKACG	5568	protein kinase, cAMP-dependent, catalytic, gamma	signal transduction	Biological process	-
ERCC2	2068	excision repair cross-complementation group 2	aging	Biological process	-
PXDN	7837	peroxidasin	negative regulation of cytokine-mediated signaling pathway	Biological process	11103812
NKX3-1	4824	NK3 homeobox 1	positive regulation of cell death	Biological process	19266349
TBX1	6899	T-box 1	artery morphogenesis	Biological process	-
BMP2	650	bone morphogenetic protein 2	heart development	Biological process	-
AQP1	358	aquaporin 1 (Colton blood group)	metanephric proximal convoluted tubule segment 2 development	Biological process	-
PRAMEF9	343070	PRAME family member 9	negative regulation of transcription, DNA-templated	Biological process	-
MAF1	84232	MAF1 homolog (S. cerevisiae)	nucleoplasm	Cellular component	-
DNAH7	56171	dynein, axonemal, heavy chain 7	ATPase activity	Molecular function	-
CHMP2A	27243	charged multivesicular body protein 2A	protein polymerization	Biological process	23051622
SYT7	9066	synaptotagmin VII	protein binding	Molecular function	25416956
TPX2	22974	TPX2, microtubule-associated	GTP binding	Molecular function	10512675
MRPL49	740	mitochondrial ribosomal protein L49	mitochondrial ribosome	Cellular component	20601428
ATP13A4	84239	ATPase type 13A4	ATP binding	Molecular function	-
TUBB3	10381	tubulin, beta 3 class III	neuronal cell body	Cellular component	-
BBS1	582	Bardet-Biedl syndrome 1	BBSome	Cellular component	17574030
AAAS	8086	achalasia, adrenocortical insufficiency, alacrimia	cellular response to heat	Biological process	-
OR1F1	4992	olfactory receptor, family 1, subfamily F, member 1	detection of chemical stimulus involved in sensory perception of smell	Biological process	-
BST2	684	bone marrow stromal cell antigen 2	apical plasma membrane	Cellular component	-
ZNF404	342908	zinc finger protein 404	regulation of transcription, DNA-templated	Biological process	-
XPR1	9213	xenotropic and polytropic retrovirus receptor 1	Golgi apparatus	Cellular component	-
IMP3	55272	IMP3, U3 small nucleolar ribonucleoprotein	protein binding	Molecular function	12655004
MAPK8	5599	mitogen-activated protein kinase 8	innate immune response	Biological process	-
CASP9	842	caspase 9, apoptosis-related cysteine peptidase	aging	Biological process	-
CXCL9	4283	chemokine (C-X-C motif) ligand 9	positive regulation of cAMP-mediated signaling	Biological process	12782716
EXOC4	60412	exocyst complex component 4	plasma membrane	Cellular component	-
DICER1	23405	dicer 1, ribonuclease type III	positive regulation of gene expression	Biological process	-
ATP8A1	10396	ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1	cation-transporting ATPase activity	Molecular function	10198212
REV1	51455	REV1, polymerase (DNA directed)	error-prone translesion synthesis	Biological process	11485998
TAF1A	9015	TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa	negative regulation of gene expression, epigenetic	Biological process	-
MICU3	286097	mitochondrial calcium uptake family, member 3	calcium ion binding	Molecular function	-
NACC2	138151	NACC family member 2, BEN and BTB (POZ) domain containing	nucleus	Cellular component	-
SLC26A3	1811	solute carrier family 26 (anion exchanger), member 3	anion:anion antiporter activity	Molecular function	-
NTF3	4908	neurotrophin 3	regulation of neuron differentiation	Biological process	-
RSF1	51773	remodeling and spacing factor 1	nucleosome positioning	Biological process	9836642
TMEM160	54958	transmembrane protein 160	mitochondrion	Cellular component	-
FLVCR1	28982	feline leukemia virus subgroup C cellular receptor 1	erythrocyte maturation	Biological process	-
PAFAH1B1	5048	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	osteoclast development	Biological process	-
CHP1	11261	calcineurin-like EF-hand protein 1	focal adhesion	Cellular component	21423176
EDN1	1906	endothelin 1	in utero embryonic development	Biological process	-
TIGAR	57103	TP53 induced glycolysis regulatory phosphatase	negative regulation of reactive oxygen species metabolic process	Biological process	-
TSPYL2	64061	TSPY-like 2	negative regulation of cell cycle	Biological process	11395479
AEBP1	165	AE binding protein 1	extracellular exosome	Cellular component	19199708
KDM3B	51780	lysine (K)-specific demethylase 3B	regulation of transcription, DNA-templated	Biological process	-
TICRR	90381	TOPBP1-interacting checkpoint and replication regulator	DNA repair	Biological process	-
HMOX1	3162	heme oxygenase 1	signal transducer activity	Molecular function	12761501
MAP3K14	9020	mitogen-activated protein kinase kinase kinase 14	signal transduction by protein phosphorylation	Biological process	-
RALA	5898	v-ral simian leukemia viral oncogene homolog A (ras related)	chemotaxis	Biological process	10848592
PLA2G15	23659	phospholipase A2, group XV	fatty acid catabolic process	Biological process	10092508
PTPN6	5777	protein tyrosine phosphatase, non-receptor type 6	positive regulation of phosphatidylinositol 3-kinase signaling	Biological process	19838216
ASCC1	51008	activating signal cointegrator 1 complex subunit 1	regulation of transcription, DNA-templated	Biological process	12077347
STAB1	23166	stabilin 1	protein disulfide oxidoreductase activity	Molecular function	12077138
PRAMEF10	343071	PRAME family member 10	negative regulation of cell differentiation	Biological process	-
OR11H12	440153	olfactory receptor, family 11, subfamily H, member 12	integral component of membrane	Cellular component	-
CIB1	10519	calcium and integrin binding 1 (calmyrin)	cytoplasm	Cellular component	10366599
CDH1	999	cadherin 1, type 1, E-cadherin (epithelial)	cytoplasmic side of plasma membrane	Cellular component	20189993
CD72	971	CD72 molecule	signal transduction	Biological process	1711157
PNPLA8	50640	patatin-like phospholipase domain containing 8	phosphatidylethanolamine acyl-chain remodeling	Biological process	-
GTSE1	51512	G-2 and S-phase expressed 1	membrane	Cellular component	19946888
TNRC6C	57690	trinucleotide repeat containing 6C	neurotrophin TRK receptor signaling pathway	Biological process	-
NPC1	4864	Niemann-Pick disease, type C1	perinuclear region of cytoplasm	Cellular component	12554680
STAR	6770	steroidogenic acute regulatory protein	cholesterol binding	Molecular function	-
RPL19	6143	ribosomal protein L19	translational initiation	Biological process	-
SLC12A7	10723	solute carrier family 12 (potassium/chloride transporter), member 7	potassium:chloride symporter activity	Molecular function	-
ACAA1	30	acetyl-CoA acyltransferase 1	unsaturated fatty acid metabolic process	Biological process	-
ADCY4	196883	adenylate cyclase 4	cytoplasm	Cellular component	11549699
TMEM216	51259	transmembrane protein 216	cilium	Cellular component	22282472
NQO1	1728	NAD(P)H dehydrogenase, quinone 1	negative regulation of catalytic activity	Biological process	-
SOX8	30812	SRY (sex determining region Y)-box 8	positive regulation of gliogenesis	Biological process	-
TOMM70A	9868	translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)	mitochondrion	Cellular component	-
GSK3B	2932	glycogen synthase kinase 3 beta	glycogen metabolic process	Biological process	8638126
AGRN	375790	agrin	cell surface	Cellular component	-
OR8A1	390275	olfactory receptor, family 8, subfamily A, member 1	odorant binding	Molecular function	-
SLC9A5	6553	solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5	ion transport	Biological process	-
LILRB2	10288	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	negative regulation of immune response	Biological process	22802125
CALCR	799	calcitonin receptor	receptor internalization	Biological process	10882736
MSRA	4482	methionine sulfoxide reductase A	cellular protein modification process	Biological process	10452521
SKAP2	8935	src kinase associated phosphoprotein 2	protein complex assembly	Biological process	9671755
SCAF1	58506	SR-related CTD-associated factor 1	RNA binding	Molecular function	-
JKAMP	51528	JNK1/MAPK8-associated membrane protein	response to unfolded protein	Biological process	-
ZNRF2	223082	zinc and ring finger 2, E3 ubiquitin protein ligase	zinc ion binding	Molecular function	-
NEUROG1	4762	neurogenin 1	nucleus	Cellular component	-
TGFB3	7043	transforming growth factor, beta 3	extracellular region	Cellular component	-
HR	55806	hair growth associated	negative regulation of transcription, DNA-templated	Biological process	-
GNAS	2778	GNAS complex locus	intrinsic component of membrane	Cellular component	7997272
VAV3	10451	vav 3 guanine nucleotide exchange factor	ephrin receptor signaling pathway	Biological process	-
BCAS4	55653	breast carcinoma amplified sequence 4	cytoplasm	Cellular component	-
LDLR	3949	low density lipoprotein receptor	integral component of plasma membrane	Cellular component	6327078
ST3GAL3	6487	ST3 beta-galactoside alpha-2,3-sialyltransferase 3	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity	Molecular function	-
RBPJ	3516	recombination signal binding protein for immunoglobulin kappa J region	dorsal aorta morphogenesis	Biological process	-
RPL37	6167	ribosomal protein L37	cytosolic large ribosomal subunit	Cellular component	7545944
TRIM32	22954	tripartite motif containing 32	myosin binding	Molecular function	-
IFIT5	24138	interferon-induced protein with tetratricopeptide repeats 5	tRNA binding	Molecular function	23317505
TICAM2	353376	toll-like receptor adaptor molecule 2	phospholipid binding	Molecular function	-
ADCYAP1	116	adenylate cyclase activating polypeptide 1 (pituitary)	regulation of G-protein coupled receptor protein signaling pathway	Biological process	11175907
UBE2A	7319	ubiquitin-conjugating enzyme E2A	cytosol	Cellular component	-
RAB11A	8766	RAB11A, member RAS oncogene family	regulation of protein transport	Biological process	-
ERCC4	2072	excision repair cross-complementation group 4	transcription-coupled nucleotide-excision repair	Biological process	-
APH1A	51107	APH1A gamma secretase subunit	protein processing	Biological process	15274632
KLF9	687	Kruppel-like factor 9	nucleus	Cellular component	22711835
TRIM29	23650	tripartite motif containing 29	zinc ion binding	Molecular function	-
TP53	7157	tumor protein p53	positive regulation of release of cytochrome c from mitochondria	Biological process	12667443
TTYH1	57348	tweety family member 1	cell-substrate adhesion	Biological process	-
CD38	952	CD38 molecule	female pregnancy	Biological process	-
CHD7	55636	chromodomain helicase DNA binding protein 7	rRNA processing	Biological process	-
DUSP14	11072	dual specificity phosphatase 14	protein binding	Molecular function	25416956
PGM3	5238	phosphoglucomutase 3	dolichol-linked oligosaccharide biosynthetic process	Biological process	-
TRANK1	9881	tetratricopeptide repeat and ankyrin repeat containing 1	hydrolase activity	Molecular function	-
B3GNT5	84002	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5	central nervous system development	Biological process	11384981
SFRP1	6422	secreted frizzled-related protein 1	negative regulation of epithelial to mesenchymal transition	Biological process	19095296
DAPK2	23604	death-associated protein kinase 2	cytoplasm	Cellular component	10376525
HIST1H4J	8363	histone cluster 1, H4j	negative regulation of gene expression, epigenetic	Biological process	-
XPO6	23214	exportin 6	protein export from nucleus	Biological process	14592989
UGT1A1	54658	UDP glucuronosyltransferase 1 family, polypeptide A1	negative regulation of fatty acid metabolic process	Biological process	20610558
COLEC12	81035	collectin sub-family member 12	signaling pattern recognition receptor activity	Molecular function	11564734
PPP1R17	10842	protein phosphatase 1, regulatory subunit 17	negative regulation of catalytic activity	Biological process	-
CACNG8	59283	calcium channel, voltage-dependent, gamma subunit 8	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity	Biological process	20805473
UTS2	10911	urotensin 2	positive regulation of angiogenesis	Biological process	-
PLXNB1	5364	plexin B1	plasma membrane	Cellular component	-
LATS2	26524	large tumor suppressor kinase 2	protein serine/threonine kinase activity	Molecular function	-
GATA4	2626	GATA binding protein 4	gastrulation with mouth forming second	Biological process	-
SH3BGRL	6451	SH3 domain binding glutamate-rich protein like	positive regulation of signal transduction	Biological process	9642120
ARID3C	138715	AT rich interactive domain 3C (BRIGHT-like)	nucleus	Cellular component	-
NCOA3	8202	nuclear receptor coactivator 3	cellular response to estradiol stimulus	Biological process	15831516
EPHB4	2050	EPH receptor B4	cell adhesion	Biological process	12734395
PPP1R10	5514	protein phosphatase 1, regulatory subunit 10	protein import into nucleus	Biological process	9461602
FLVCR1	28982	feline leukemia virus subgroup C cellular receptor 1	multicellular organism growth	Biological process	-
KLF4	9314	Kruppel-like factor 4 (gut)	transcription from RNA polymerase II promoter	Biological process	-
DNPH1	10591	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	nucleus	Cellular component	-
BRAF	673	B-Raf proto-oncogene, serine/threonine kinase	cell body	Cellular component	-
PARK2	5071	parkin RBR E3 ubiquitin protein ligase	proteasomal protein catabolic process	Biological process	19725078
ZNF623	9831	zinc finger protein 623	metal ion binding	Molecular function	-
ATG7	10533	autophagy related 7	negative stranded viral RNA replication	Biological process	-
EIF3B	8662	eukaryotic translation initiation factor 3, subunit B	regulation of translational initiation	Biological process	8995410
SMAD9	4093	SMAD family member 9	positive regulation of transcription, DNA-templated	Biological process	-
CNOT3	4849	CCR4-NOT transcription complex, subunit 3	gene expression	Biological process	-
SPRY2	10253	sprouty homolog 2 (Drosophila)	microtubule	Cellular component	-
FADD	8772	Fas (TNFRSF6)-associated via death domain	positive regulation of tumor necrosis factor production	Biological process	16127453
PPP1R3F	89801	protein phosphatase 1, regulatory subunit 3F	membrane	Cellular component	21668450
C1orf52	148423	chromosome 1 open reading frame 52	nucleoplasm	Cellular component	-
NPL	80896	N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)	cytosol	Cellular component	-
DDX60	55601	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	single-stranded RNA binding	Molecular function	21791617
KCNJ3	3760	potassium channel, inwardly rectifying subfamily J, member 3	external side of plasma membrane	Cellular component	-
C2	717	complement component 2	extracellular space	Cellular component	8621452
IL23A	51561	interleukin 23, alpha subunit p19	positive regulation of T-helper 17 cell lineage commitment	Biological process	-
ITGB1	3688	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	protein binding	Molecular function	10604475
OR11L1	391189	olfactory receptor, family 11, subfamily L, member 1	integral component of plasma membrane	Cellular component	-
SAV1	60485	salvador family WW domain containing protein 1	negative regulation of epithelial cell proliferation	Biological process	-
ATP6V0A4	50617	ATPase, H+ transporting, lysosomal V0 subunit a4	vacuolar acidification	Biological process	-
RFC4	5984	replication factor C (activator 1) 4, 37kDa	transcription-coupled nucleotide-excision repair	Biological process	-
OR4A8	81315	olfactory receptor, family 4, subfamily A, member 8 (gene/pseudogene)	G-protein coupled receptor signaling pathway	Biological process	-
NDOR1	27158	NADPH dependent diflavin oxidoreductase 1	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	Molecular function	-
LRRC37B	114659	leucine rich repeat containing 37B	cytoplasm	Cellular component	-
POLR1E	64425	polymerase (RNA) I polypeptide E, 53kDa	transcription elongation from RNA polymerase I promoter	Biological process	-
TAGLN2	8407	transgelin 2	vesicle	Cellular component	19190083
RXRA	6256	retinoid X receptor, alpha	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus	Biological process	-
CENPW	387103	centromere protein W	nucleolus	Cellular component	-
POM121	9883	POM121 transmembrane nucleoporin	gene expression	Biological process	-
PFKM	5213	phosphofructokinase, muscle	sperm principal piece	Cellular component	-
IFNAR2	3455	interferon (alpha, beta and omega) receptor 2	cytokine-mediated signaling pathway	Biological process	-
BMP3	651	bone morphogenetic protein 3	extracellular exosome	Cellular component	19199708
PECAM1	5175	platelet/endothelial cell adhesion molecule 1	extracellular matrix organization	Biological process	-
MDM1	56890	Mdm1 nuclear protein homolog (mouse)	retina development in camera-type eye	Biological process	-
INPP5E	56623	inositol polyphosphate-5-phosphatase, 72 kDa	primary cilium	Cellular component	-
PDPN	10630	podoplanin	lymphangiogenesis	Biological process	-
TDP2	51567	tyrosyl-DNA phosphodiesterase 2	nucleoplasm	Cellular component	-
ASB3	51130	ankyrin repeat and SOCS box containing 3	protein binding	Molecular function	25814554
TCTE3	6991	t-complex-associated-testis-expressed 3	motor activity	Molecular function	-
WNK3	65267	WNK lysine deficient protein kinase 3	positive regulation of calcium ion transport	Biological process	18768590
GAS6	2621	growth arrest-specific 6	extracellular space	Cellular component	18395422
LIMK1	3984	LIM domain kinase 1	nervous system development	Biological process	8689688
PFKFB1	5207	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	fructose metabolic process	Biological process	-
TNFSF15	9966	tumor necrosis factor (ligand) superfamily, member 15	extracellular space	Cellular component	-
ANLN	54443	anillin, actin binding protein	actomyosin contractile ring	Cellular component	10931866
SUPV3L1	6832	suppressor of var1, 3-like 1 (S. cerevisiae)	positive regulation of mitochondrial RNA catabolic process	Biological process	19864255
WDR75	84128	WD repeat domain 75	nucleoplasm	Cellular component	-
PRDM13	59336	PR domain containing 13	methylation	Biological process	-
APEX1	328	APEX nuclease (multifunctional DNA repair enzyme) 1	DNA strand elongation involved in DNA replication	Biological process	-
OPRM1	4988	opioid receptor, mu 1	sensory perception	Biological process	9689128
LONP1	9361	lon peptidase 1, mitochondrial	serine-type endopeptidase activity	Molecular function	-
APOA5	116519	apolipoprotein A-V	low-density lipoprotein particle receptor binding	Molecular function	17326667
CEP290	80184	centrosomal protein 290kDa	ciliary transition zone	Cellular component	23943788
PHOX2B	8929	paired-like homeobox 2b	RNA polymerase II core promoter proximal region sequence-specific DNA binding	Molecular function	16144830
PRPF18	8559	pre-mRNA processing factor 18	nucleus	Cellular component	9000057
CYP4F22	126410	cytochrome P450, family 4, subfamily F, polypeptide 22	oxidation-reduction process	Biological process	-
NOSTRIN	115677	nitric oxide synthase trafficking	DNA binding	Molecular function	-
UBE2V2	7336	ubiquitin-conjugating enzyme E2 variant 2	positive regulation of synapse assembly	Biological process	-
UGT1A7	54577	UDP glucuronosyltransferase 1 family, polypeptide A7	coumarin metabolic process	Biological process	19996319
NEXN	91624	nexilin (F actin binding protein)	structural constituent of muscle	Molecular function	19881492
CLDN2	9075	claudin 2	extracellular exosome	Cellular component	23376485
TACO1	51204	translational activator of mitochondrially encoded cytochrome c oxidase I	nucleus	Cellular component	-
KIF19	124602	kinesin family member 19	plus-end specific microtubule depolymerization	Biological process	-
FGF3	2248	fibroblast growth factor 3	growth factor activity	Molecular function	-
BNIP3	664	BCL2/adenovirus E1B 19kDa interacting protein 3	nucleus	Cellular component	-
HIST1H1E	3008	histone cluster 1, H1e	nucleosome assembly	Biological process	-
TGFB1I1	7041	transforming growth factor beta 1 induced transcript 1	androgen receptor binding	Molecular function	15572661
COL4A2	1284	collagen, type IV, alpha 2	extracellular matrix disassembly	Biological process	-
TBX2	6909	T-box 2	cellular senescence	Biological process	22002537
TGFB1	7040	transforming growth factor, beta 1	regulation of branching involved in mammary gland duct morphogenesis	Biological process	-
KRT71	112802	keratin 71, type II	protein binding	Molecular function	25416956
UGT2B7	7364	UDP glucuronosyltransferase 2 family, polypeptide B7	cellular response to hormone stimulus	Biological process	-
IRG1	730249	immunoresponsive 1 homolog (mouse)	inflammatory response	Biological process	-
TDRD9	122402	tudor domain containing 9	poly(A) RNA binding	Molecular function	-
PRELID1	27166	PRELI domain containing 1	mitochondrion	Cellular component	-
HES2	54626	hes family bHLH transcription factor 2	transcription, DNA-templated	Biological process	-
DYRK1A	1859	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	ribonucleoprotein complex	Cellular component	-
SIX1	6495	SIX homeobox 1	regulation of neuron differentiation	Biological process	-
PEX11B	8799	peroxisomal biogenesis factor 11 beta	peroxisome fission	Biological process	17408615
SNRPGP15	100130932	small nuclear ribonucleoprotein polypeptide G pseudogene 15	small nucleolar ribonucleoprotein complex	Cellular component	-
SHARPIN	81858	SHANK-associated RH domain interactor	negative regulation of inflammatory response	Biological process	-
HMG20A	10363	high mobility group 20A	chromatin remodeling	Biological process	-
NEK1	4750	NIMA-related kinase 1	protein serine/threonine kinase activity	Molecular function	-
FETUB	26998	fetuin B	biological_process	Biological process	-
HBEGF	1839	heparin-binding EGF-like growth factor	neurotrophin TRK receptor signaling pathway	Biological process	-
CEP63	80254	centrosomal protein 63kDa	protein binding	Molecular function	12812986
ALDH7A1	501	aldehyde dehydrogenase 7 family, member A1	extracellular exosome	Cellular component	23376485
TUBB	203068	tubulin, beta class I	G2/M transition of mitotic cell cycle	Biological process	-
SUPT4H1	6827	suppressor of Ty 4 homolog 1 (S. cerevisiae)	DSIF complex	Cellular component	9450929
SLC2A1	6513	solute carrier family 2 (facilitated glucose transporter), member 1	D-glucose transmembrane transporter activity	Molecular function	-
CSRP3	8048	cysteine and glycine-rich protein 3 (cardiac LIM protein)	nucleus	Cellular component	-
SARM1	23098	sterile alpha and TIR motif containing 1	toll-like receptor signaling pathway	Biological process	-
CLK2	1196	CDC-like kinase 2	regulation of RNA splicing	Biological process	9637771
APIP	51074	APAF1 interacting protein	methylthioribulose 1-phosphate dehydratase activity	Molecular function	-
EDF1	8721	endothelial differentiation-related factor 1	sequence-specific DNA binding	Molecular function	-
GDPGP1	390637	GDP-D-glucose phosphorylase 1	glucose metabolic process	Biological process	21507950
VDR	7421	vitamin D (1,25- dihydroxyvitamin D3) receptor	sequence-specific DNA binding	Molecular function	-
P2RX7	5027	purinergic receptor P2X, ligand gated ion channel, 7	cell surface receptor signaling pathway	Biological process	-
TP53	7157	tumor protein p53	RNA polymerase II transcription factor binding	Molecular function	18549481
CAPZB	832	capping protein (actin filament) muscle Z-line,